"Checked"	"Protein FDR Confidence: MS Amanda 2.0"	"Protein FDR Confidence: Sequest HT"	"Master"	"Accession"	"Description"	"Exp. q-value: MS Amanda 2.0"	"Exp. q-value: Sequest HT"	"Coverage [%]"	"# Peptides"	"# PSMs"	"# Unique Peptides"	"# AAs"	"MW [kDa]"	"calc. pI"	"Score MS Amanda 2.0: MS Amanda 2.0"	"Score Sequest HT: Sequest HT"	"# Peptides (by Search Engine): MS Amanda 2.0"	"# Peptides (by Search Engine): Sequest HT"	"Biological Process"	"Cellular Component"	"Molecular Function"	"Pfam IDs"	"Entrez Gene ID"	"Ensembl Gene ID"	"Gene Symbol"	"Gene ID"	"WikiPathways"	"Reactome Pathways"	"# Protein Pathway Groups"	"# Razor Peptides"	"Abundances (Grouped): 126"	"Abundances (Grouped): 127N"	"Abundances (Grouped): 127C"	"Abundances (Grouped): 128N"	"Abundances (Grouped): 128C"	"Abundances (Grouped): 129N"	"Abundances (Grouped): 129C"	"Abundances (Grouped): 130N"	"Abundances (Grouped): 130C"	"Abundances (Grouped): 131N"	"Abundances (Grouped): 131C"	"Abundances (Grouped) CV [%]: 126"	"Abundances (Grouped) CV [%]: 127N"	"Abundances (Grouped) CV [%]: 127C"	"Abundances (Grouped) CV [%]: 128N"	"Abundances (Grouped) CV [%]: 128C"	"Abundances (Grouped) CV [%]: 129N"	"Abundances (Grouped) CV [%]: 129C"	"Abundances (Grouped) CV [%]: 130N"	"Abundances (Grouped) CV [%]: 130C"	"Abundances (Grouped) CV [%]: 131N"	"Abundances (Grouped) CV [%]: 131C"	"Found in Sample: F8: 126, Sample"	"Found in Sample: F8: 127N, Sample"	"Found in Sample: F8: 127C, Sample"	"Found in Sample: F8: 128N, Sample"	"Found in Sample: F8: 128C, Sample"	"Found in Sample: F8: 129N, Sample"	"Found in Sample: F8: 129C, Sample"	"Found in Sample: F8: 130N, Sample"	"Found in Sample: F8: 130C, Sample"	"Found in Sample: F8: 131N, Sample"	"Found in Sample: F8: 131C, Sample"	"# Protein Groups"	"Modifications"
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13813"	"Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3"	"0.000"	""	"58"	"142"	"332"	"142"	"2472"	"284.4"	"5.35"	"66310.34"	"716.94"	"119"	"129"	"cell organization and biogenesis"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00018, Pf00435, Pf08726, Pf13499"	"6709"	"ENSG00000197694"	"SPTAN1"	"hsa:6709; Q13186; Q13813; Q15324; Q16606; Q59EF1; Q5VXV5; Q5VXV6; Q7Z6M5; Q9P0V0"	"Fas ligand pathway and stress induction of heat shock proteins"	"Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Interaction between L1 and Ankyrins; RHOV GTPase cycle; COPI-mediated anterograde transport; Neutrophil degranulation; RHOU GTPase cycle; Nephrin family interactions; RAF/MAP kinase cascade; NCAM signaling for neurite out-growth; Caspase-mediated cleavage of cytoskeletal proteins"	"12"	"0"	"6115.4"	"4508.4"	"6316.8"	"5632.0"	"5469.6"	"5651.8"	"7553.1"	"50322.2"	"50554.1"	"101297.7"	"122941.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q01082"	"Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2"	"0.000"	""	"45"	"100"	"254"	"87"	"2364"	"274.4"	"5.57"	"56030.05"	"480.29"	"91"	"90"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00169, Pf00307, Pf00435"	"6711"	"ENSG00000115306"	"SPTBN1"	"B2RP63; hsa:6711; O60837; Q01082; Q16057; Q53R99; Q59ER3; Q8IX99"	"Sudden infant death syndrome (SIDS) susceptibility pathways"	"COPI-mediated anterograde transport; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; RHOV GTPase cycle; RHOU GTPase cycle; Nephrin family interactions; RAF/MAP kinase cascade; NCAM signaling for neurite out-growth; Interaction between L1 and Ankyrins; Signaling by FLT3 fusion proteins"	"11"	"15"	"3710.3"	"2601.7"	"3975.6"	"3564.9"	"3485.1"	"3604.2"	"4757.1"	"33008.2"	"33337.3"	"70548.3"	"87046.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P20700"	"Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2"	"0.000"	""	"75"	"66"	"215"	"58"	"586"	"66.4"	"5.16"	"37389.85"	"459.63"	"56"	"60"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytoskeleton;nucleus"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00038, Pf00932"	"4001"	"ENSG00000113368"	"LMNB1"	"B2R6J6; hsa:4001; P20700; Q3SYN7; Q96EI6"	"Fas ligand pathway and stress induction of heat shock proteins; Familial partial lipodystrophy; Progeria-associated lipodystrophy; Acquired partial lipodystrophy / Barraquer-Simons syndrome"	"Meiotic synapsis; RHOD GTPase cycle; RHOF GTPase cycle; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models; Initiation of Nuclear Envelope (NE) Reformation; Depolymerization of the Nuclear Lamina; Breakdown of the nuclear lamina; Formation of Senescence-Associated Heterochromatin Foci (SAHF)"	"14"	"9"	"11556.0"	"9205.2"	"9751.4"	"9524.4"	"8319.5"	"8783.0"	"12028.4"	"21275.4"	"21230.3"	"42720.0"	"53422.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WXH0"	"Nesprin-2 OS=Homo sapiens OX=9606 GN=SYNE2 PE=1 SV=3"	"0.000"	""	"17"	"98"	"187"	"96"	"6885"	"795.9"	"5.36"	"32023.93"	"380.26"	"80"	"94"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00435, Pf10541"	"23224"	"ENSG00000054654"	"SYNE2"	"B4DND7; B4DPR6; hsa:23224; I6XXQ5; Q540G1; Q86YP9; Q8N1S3; Q8NF49; Q8TER7; Q8WWW3; Q8WWW4; Q8WWW5; Q8WXH0; Q8WXH1; Q9NU50; Q9UFQ4; Q9Y2L4; Q9Y4R1"	"Ovarian infertility; Rett syndrome causing genes; Envelope proteins and their potential roles in EDMD physiopathology"	"Meiotic synapsis"	"4"	"0"	"2119.3"	"1654.4"	"2337.4"	"2165.1"	"2126.0"	"2303.1"	"3059.5"	"14129.4"	"15596.8"	"43786.8"	"53566.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P12270"	"Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3"	"0.000"	""	"30"	"69"	"152"	"68"	"2363"	"267.1"	"5.02"	"32203.26"	"268.04"	"67"	"61"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"other membranes;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf07926"	"7175"	"ENSG00000047410"	"TPR"	"hsa:7175; P12270; Q15624; Q15655; Q5SWY0; Q99968"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; HCMV Late Events; HCMV Early Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Signaling by ALK fusions and activated point mutants"	"29"	"1"	"7442.5"	"5407.3"	"6743.4"	"6092.2"	"5889.9"	"6284.3"	"8233.6"	"15058.5"	"14888.0"	"36384.5"	"55340.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13639"	"Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4"	"0.000"	""	"51"	"50"	"138"	"49"	"858"	"95.3"	"6.83"	"27907.48"	"266.41"	"44"	"44"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00009, Pf00679, Pf03144, Pf03764, Pf14492"	"1938"	"ENSG00000167658"	"EEF2"	"A0A384N6H1; B2RMP5; D6W618; hsa:1938; P13639; Q58J86"	"Translation factors; AMP-activated protein kinase signaling; Brain-derived neurotrophic factor (BDNF) signaling pathway; IL-18 signaling pathway"	"Neutrophil degranulation; Protein methylation; Uptake and function of diphtheria toxin; Peptide chain elongation; Synthesis of diphthamide-EEF2"	"9"	"1"	"1624.8"	"1329.8"	"1757.3"	"1541.2"	"1510.7"	"1557.8"	"2149.4"	"11860.8"	"15216.5"	"42077.8"	"59818.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08670"	"Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4"	"0.000"	""	"74"	"44"	"117"	"40"	"466"	"53.6"	"5.12"	"23301.69"	"239.96"	"33"	"41"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00038, Pf04732"	"7431"	"ENSG00000026025"	"VIM"	"B0YJC2; D3DRU4; hsa:7431; P08670; Q15867; Q15868; Q15869; Q548L2; Q6LER9; Q8N850; Q96ML2; Q9NTM3"	"Allograft rejection; Spinal cord injury; Primary focal segmental glomerulosclerosis (FSGS); Mammary gland development pathway - Puberty (Stage 2 of 4); Apoptosis-related network due to altered Notch3 in ovarian cancer; Striated muscle contraction pathway; TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition; Ciliary landscape; Burn wound healing; CCL18 signaling pathway; TROP2 regulatory signaling; CKAP4 signaling pathway map; A network map of Macrophage-stimulating protein (MSP) signaling; T-cell receptor signaling pathway"	"Aggrephagy; Interleukin-4 and Interleukin-13 signaling; Chaperone Mediated Autophagy; Late endosomal microautophagy; Striated Muscle Contraction; RHOBTB1 GTPase cycle; Caspase-mediated cleavage of cytoskeletal proteins"	"21"	"4"	"6040.7"	"3946.5"	"4936.7"	"4364.9"	"4136.4"	"4298.2"	"6168.3"	"9524.3"	"9041.2"	"17126.2"	"25597.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22626"	"Heterogeneous nuclear ribonucleoproteins A2/B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2"	"0.000"	""	"73"	"27"	"97"	"24"	"353"	"37.4"	"8.95"	"16433.07"	"235.64"	"21"	"25"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"3181"	"ENSG00000122566"	"HNRNPA2B1"	"A0A024RA27; A0A024RA61; A8K064; hsa:3181; P22626; P22627; Q9UC98; Q9UDJ2"	"mRNA processing"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"4"	"3"	"7959.3"	"7454.7"	"7382.5"	"6741.7"	"7052.5"	"6776.3"	"8954.9"	"10668.6"	"9586.0"	"15542.7"	"22857.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15020"	"Spectrin beta chain, non-erythrocytic 2 OS=Homo sapiens OX=9606 GN=SPTBN2 PE=1 SV=3"	"0.000"	""	"28"	"61"	"135"	"48"	"2390"	"271.2"	"6.11"	"28967.28"	"231.96"	"57"	"50"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00435, Pf15410"	"6712"	"ENSG00000173898"	"SPTBN2"	"hsa:6712; O14872; O14873; O15020"	""	"MHC class II antigen presentation; COPI-mediated anterograde transport; RAF/MAP kinase cascade; NCAM signaling for neurite out-growth; Interaction between L1 and Ankyrins"	"5"	"0"	"1972.7"	"1420.6"	"2017.0"	"1834.5"	"1752.2"	"1899.1"	"2466.7"	"9448.0"	"9946.5"	"27388.4"	"34597.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P02545"	"Prelamin-A/C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1"	"0.000"	""	"55"	"53"	"129"	"51"	"664"	"74.1"	"7.02"	"24323.51"	"222.54"	"49"	"50"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00038, Pf00932"	"4000"	"ENSG00000160789"	"LMNA"	"B4DI32; D3DVB0; D6RAQ3; E7EUI9; hsa:4000; P02545; P02546; Q5I6Y4; Q5I6Y6; Q5TCJ2; Q5TCJ3; Q6UYC3; Q969I8; Q96JA2"	"Arrhythmogenic right ventricular cardiomyopathy; Adipogenesis; Fas ligand pathway and stress induction of heat shock proteins; Lamin A-processing pathway; Nephrotic syndrome; Influence of laminopathies on Wnt signaling; Overlap between signal transduction pathways contributing to LMNA laminopathies; Familial partial lipodystrophy; Progeria-associated lipodystrophy; Acquired partial lipodystrophy / Barraquer-Simons syndrome; Primary ovarian insufficiency"	"XBP1(S) activates chaperone genes; Signaling by BRAF and RAF1 fusions"	"13"	"1"	"6700.3"	"4650.4"	"6145.3"	"5469.5"	"5118.7"	"5675.3"	"7970.3"	"14946.0"	"13651.0"	"26486.8"	"30363.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14683"	"Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2"	"0.000"	""	"44"	"55"	"121"	"55"	"1233"	"143.1"	"7.64"	"21467.54"	"214.58"	"48"	"48"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02463, Pf06470"	"8243"	"ENSG00000072501"	"SMC1A"	"hsa:8243; O14995; Q14683; Q16351; Q2M228"	"miRNA regulation of DNA damage response; Cell cycle; Retinoblastoma gene in cancer; Constitutive androstane receptor pathway; Nuclear receptors meta-pathway; Pathways affected in adenoid cystic carcinoma; ATM signaling in development and disease ; mRNA processing; Regulation of sister chromatid separation at the metaphase-anaphase transition; Rett syndrome causing genes; CAMKK2 pathway; Cohesin complex - Cornelia de Lange syndrome; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; 10q22q23 copy number variation; DNA damage response"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Estrogen-dependent gene expression; Meiotic synapsis; SUMOylation of DNA damage response and repair proteins; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"22"	"0"	"6200.5"	"5034.0"	"5916.8"	"5485.9"	"5396.2"	"5731.3"	"7382.5"	"13414.1"	"12996.7"	"27950.7"	"35214.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UQE7"	"Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2"	"0.000"	""	"39"	"54"	"117"	"54"	"1217"	"141.5"	"7.18"	"22903.94"	"207.70"	"50"	"47"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf02463, Pf06470"	"9126"	"ENSG00000108055"	"SMC3"	"A8K156; hsa:9126; O60464; Q5T482; Q9UQE7"	"Cell cycle; Retinoblastoma gene in cancer; MECP2 and associated Rett syndrome; Prion disease pathway; Regulation of sister chromatid separation at the metaphase-anaphase transition; Cohesin complex - Cornelia de Lange syndrome; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; 10q22q23 copy number variation"	"SUMOylation of DNA damage response and repair proteins; Meiotic synapsis; Estrogen-dependent gene expression; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"15"	"0"	"5637.6"	"4395.2"	"5500.9"	"5055.8"	"4946.5"	"5275.6"	"6731.6"	"13351.8"	"12657.9"	"28827.6"	"37133.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q03252"	"Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4"	"0.000"	""	"61"	"47"	"113"	"38"	"620"	"69.9"	"5.59"	"20871.12"	"204.00"	"43"	"44"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytoskeleton;nucleus"	"cytoskeletal activity;other molecular function"	"Pf00038, Pf00932"	"84823"	"ENSG00000176619"	"LMNB2"	"hsa:84823; O75292; Q03252; Q14734; Q96DF6"	"Gastric cancer network 2; Fas ligand pathway and stress induction of heat shock proteins; IL-18 signaling pathway; Familial partial lipodystrophy; Progeria-associated lipodystrophy; Acquired partial lipodystrophy / Barraquer-Simons syndrome"	""	"6"	"0"	"6125.7"	"4606.5"	"5406.3"	"5149.9"	"4399.9"	"4863.9"	"6373.1"	"10214.4"	"10308.0"	"20303.6"	"25120.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q09666"	"Neuroblast differentiation-associated protein AHNAK OS=Homo sapiens OX=9606 GN=AHNAK PE=1 SV=2"	"0.000"	""	"22"	"43"	"91"	"43"	"5890"	"628.7"	"6.15"	"16251.17"	"188.61"	"33"	"42"	"other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	""	"79026"	"ENSG00000124942"	"AHNAK"	"A1A586; hsa:79026; Q09666"	""	""	"0"	"0"	"1714.8"	"1246.0"	"1716.1"	"1495.2"	"1403.2"	"1527.8"	"1884.6"	"6474.9"	"6680.8"	"15291.8"	"22861.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15149"	"Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3"	"0.000"	""	"14"	"52"	"92"	"49"	"4684"	"531.5"	"5.96"	"16880.61"	"188.57"	"43"	"49"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00681, Pf03501, Pf17902, Pf18373"	"5339"	"ENSG00000178209"	"PLEC"	"hsa:5339; Q15148; Q15149; Q16640; Q6S376; Q6S377; Q6S378; Q6S379; Q6S380; Q6S381; Q6S382; Q6S383"	"Envelope proteins and their potential roles in EDMD physiopathology"	"Assembly of collagen fibrils and other multimeric structures; Caspase-mediated cleavage of cytoskeletal proteins; Type I hemidesmosome assembly"	"4"	"3"	"3175.6"	"2550.4"	"3224.0"	"2925.5"	"2886.7"	"2960.5"	"3815.7"	"5990.1"	"5837.6"	"13335.5"	"19604.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08133"	"Annexin A6 OS=Homo sapiens OX=9606 GN=ANXA6 PE=1 SV=3"	"0.000"	""	"57"	"33"	"84"	"33"	"673"	"75.8"	"5.60"	"12919.68"	"185.25"	"20"	"32"	"cell organization and biogenesis;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;mitochondrion;other cytoplasmic organelle;other cell component"	"transporter activity;cytoskeletal activity;other molecular function"	"Pf00191"	"309"	"ENSG00000197043"	"ANXA6"	"B7Z8A7; D3DQH4; E9PGK1; hsa:309; P08133; Q6ZT79"	"Calcium regulation in cardiac cells; Prostaglandin synthesis and regulation"	"Smooth Muscle Contraction"	"3"	"0"	"798.1"	"513.0"	"863.7"	"796.8"	"787.2"	"843.3"	"981.6"	"3112.4"	"2898.5"	"21649.1"	"54355.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61978"	"Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1"	"0.000"	""	"54"	"26"	"88"	"26"	"463"	"50.9"	"5.54"	"17122.43"	"176.82"	"21"	"24"	"RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf08067"	"3190"	"ENSG00000165119"	"HNRNPK"	"hsa:3190; P61978; Q07244; Q15671; Q59F98; Q5T6W4; Q60577; Q6IBN1; Q922Y7; Q96J62"	"mRNA processing; lncRNA in canonical Wnt signaling and colorectal cancer"	"mRNA Splicing - Major Pathway; HCMV Late Events; SUMOylation of RNA binding proteins; Processing of Capped Intron-Containing Pre-mRNA"	"6"	"0"	"4466.5"	"4257.2"	"4598.0"	"4310.4"	"4555.4"	"4335.9"	"5470.0"	"8496.6"	"7994.2"	"16204.7"	"25448.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75643"	"U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2"	"0.000"	""	"27"	"47"	"92"	"47"	"2136"	"244.4"	"6.06"	"17917.04"	"172.67"	"40"	"41"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00270, Pf00271, Pf02889, Pf18149"	"23020"	"ENSG00000144028"	"SNRNP200"	"hsa:23020; O75643; O94884; Q6NZY0; Q6PX59; Q8NBE6; Q96IF2; Q9H7S0"	"2q11.2 copy number variation syndrome"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"3"	"0"	"2295.1"	"1826.5"	"2328.9"	"2165.7"	"1964.4"	"2014.1"	"2879.6"	"5024.0"	"4989.7"	"17120.5"	"31342.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q00839"	"Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6"	"0.000"	""	"43"	"39"	"92"	"38"	"825"	"90.5"	"6.00"	"18105.50"	"155.28"	"27"	"32"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00622, Pf02037, Pf13671"	"3192"	"ENSG00000153187"	"HNRNPU"	"hsa:3192; O75507; Q00839; Q8N174; Q96HY9; Q9BQ09"	"mRNA processing; lncRNA in canonical Wnt signaling and colorectal cancer"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"4"	"1"	"6686.3"	"5455.6"	"6391.3"	"5820.4"	"5617.6"	"5888.0"	"8129.1"	"11140.8"	"10422.8"	"21655.1"	"35276.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q08211"	"ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4"	"0.000"	""	"32"	"33"	"78"	"33"	"1270"	"140.9"	"6.84"	"16864.74"	"152.21"	"29"	"28"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;cytoskeleton;translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00035, Pf00270, Pf00271, Pf04408, Pf07717"	"1660"	"ENSG00000135829"	"DHX9"	"B2RNV4; hsa:1660; Q05CI5; Q08211; Q12803; Q32Q22; Q5VY62; Q6PD69; Q99556"	"MECP2 and associated Rett syndrome; mRNA processing"	"mRNA Splicing - Major Pathway; RIP-mediated NFkB activation via ZBP1; DEx/H-box helicases activate type I IFN and inflammatory cytokines production"	"5"	"0"	"2000.3"	"1871.5"	"1941.6"	"1849.9"	"1831.1"	"1800.3"	"2632.8"	"4079.1"	"3902.7"	"10044.7"	"17181.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11142"	"Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1"	"0.000"	""	"53"	"34"	"77"	"28"	"646"	"70.9"	"5.52"	"14992.77"	"149.06"	"30"	"31"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00012"	"3312"	"ENSG00000109971"	"HSPA8"	"hsa:3312; P11142; Q9H3R6"	"Parkin-ubiquitin proteasomal system pathway; MAPK signaling pathway; Exercise-induced circadian regulation; Measles virus infection; Opioid receptor pathways; Extrafollicular and follicular B cell activation by SARS-CoV-2; 1p36 copy number variation syndrome"	"AUF1 (hnRNP D0) binds and destabilizes mRNA; Neutrophil degranulation; mRNA Splicing - Major Pathway; Golgi Associated Vesicle Biogenesis; Late endosomal microautophagy; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Regulation of HSF1-mediated heat shock response; Lysosome Vesicle Biogenesis; Clathrin-mediated endocytosis; CHL1 interactions; Interleukin-4 and Interleukin-13 signaling; GABA synthesis, release, reuptake and degradation; Lipophagy; Chaperone Mediated Autophagy; Protein methylation; Attenuation phase"	"24"	"7"	"3522.3"	"2517.7"	"3423.2"	"3184.1"	"2952.3"	"3190.1"	"4261.6"	"6999.8"	"7157.0"	"15659.7"	"22459.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14980"	"Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2"	"0.000"	""	"24"	"42"	"78"	"42"	"2115"	"238.1"	"5.78"	"16767.16"	"148.98"	"39"	"36"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	""	"4926"	"ENSG00000137497"	"NUMA1"	"H0YH75; hsa:4926; Q14980; Q14981; Q9BTE9"	"Ectoderm differentiation; Ectoderm differentiation; 8p23.1 copy number variation syndrome"	"Recruitment of NuMA to mitotic centrosomes; Mitotic Prophase"	"5"	"0"	"3302.6"	"2588.1"	"3044.0"	"2764.2"	"2786.9"	"2788.7"	"3579.9"	"5693.3"	"5514.5"	"11932.6"	"17340.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43491"	"Band 4.1-like protein 2 OS=Homo sapiens OX=9606 GN=EPB41L2 PE=1 SV=1"	"0.000"	""	"34"	"32"	"71"	"28"	"1005"	"112.5"	"5.44"	"13170.95"	"145.07"	"28"	"30"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf04382, Pf05902, Pf08736, Pf09379, Pf09380"	"2037"	"ENSG00000079819"	"EPB41L2"	"B4DHI8; E9PPD9; hsa:2037; O43491; Q5T4F0; Q68DV2"	"Splicing factor NOVA regulated synaptic proteins"	"Neurexins and neuroligins"	"2"	"4"	"3180.0"	"2440.1"	"2858.4"	"2778.1"	"2556.3"	"2659.5"	"3438.5"	"6201.5"	"6057.5"	"16473.4"	"20931.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P04264"	"Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6"	"0.000"	""	"37"	"29"	"75"	"25"	"644"	"66.0"	"8.12"	"14381.79"	"141.10"	"27"	"27"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"bone, tooth or skin structural activity;other molecular function"	"Pf00038, Pf16208, Pf16210"	"3848"	"ENSG00000167768"	"KRT1"	"B2RA01; hsa:3848; P04264; P85925; P86104; Q14720; Q6GSJ0; Q9H298"	"Corticotropin-releasing hormone signaling pathway"	"Formation of the cornified envelope; Neutrophil degranulation"	"4"	"4"	"1101.6"	"1545.8"	"8526.9"	"2410.1"	"3251.3"	"1501.2"	"1733.7"	"5574.9"	"8722.9"	"10437.9"	"11806.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43390"	"Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1"	"0.000"	""	"48"	"27"	"69"	"17"	"633"	"70.9"	"8.13"	"12584.65"	"139.07"	"24"	"26"	"RNA metabolism OR transcription;other metabolic processes"	"ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf18360"	"10236"	"ENSG00000125944; ENSG00000282958"	"HNRNPR"	"hsa:10236; O43390; Q2L7G6; Q5TEH1; Q9BV64; S4R3J4"	"mRNA processing"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"3"	"11"	"4232.9"	"3409.4"	"4263.7"	"3717.8"	"3687.8"	"3597.1"	"4971.0"	"6382.5"	"5855.9"	"10316.2"	"15429.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P54577"	"Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4"	"0.000"	""	"63"	"37"	"87"	"37"	"528"	"59.1"	"7.05"	"16631.53"	"138.59"	"35"	"33"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00579, Pf01588"	"8565"	"ENSG00000134684"	"YARS1"	"B3KWK4; D3DPQ4; hsa:8565; O43276; P54577; Q53EN1"	"Nephrotic syndrome"	"Cytosolic tRNA aminoacylation"	"2"	"0"	"3002.6"	"2421.0"	"2740.7"	"2541.2"	"2525.3"	"2647.8"	"3614.9"	"11913.9"	"11843.2"	"31901.3"	"42258.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7KZF4"	"Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1"	"0.000"	""	"37"	"27"	"56"	"27"	"910"	"101.9"	"7.17"	"9867.82"	"135.57"	"20"	"27"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00565, Pf00567"	"27044"	"ENSG00000197157"	"SND1"	"hsa:27044; Q13122; Q7KZF4; Q96AG0"	"VEGFA-VEGFR2 signaling"	"Signaling by BRAF and RAF1 fusions"	"2"	"0"	"1113.7"	"896.3"	"1197.3"	"1054.5"	"1113.7"	"1119.9"	"1456.0"	"3085.2"	"3228.5"	"11460.2"	"19221.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P26639"	"Threonine--tRNA ligase 1, cytoplasmic OS=Homo sapiens OX=9606 GN=TARS1 PE=1 SV=3"	"0.000"	""	"49"	"32"	"65"	"32"	"723"	"83.4"	"6.67"	"11458.95"	"132.31"	"22"	"31"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol"	"nucleic acid binding activity;other molecular function"	"Pf00587, Pf02824, Pf03129, Pf07973"	"6897"	"ENSG00000113407"	"TARS1"	"A8K8I1; B4DEG8; hsa:6897; P26639; Q96FP5; Q9BWA6"	""	"Cytosolic tRNA aminoacylation"	"1"	"0"	"575.8"	"424.6"	"587.8"	"539.6"	"552.6"	"808.5"	"1374.8"	"7683.1"	"7791.7"	"18823.2"	"28385.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5JRX3"	"Presequence protease, mitochondrial OS=Homo sapiens OX=9606 GN=PITRM1 PE=1 SV=3"	"0.000"	""	"32"	"29"	"62"	"29"	"1037"	"117.3"	"6.92"	"11306.71"	"131.70"	"24"	"27"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport"	"mitochondrion"	"enzyme regulator activity;other molecular function"	"Pf00675, Pf05193, Pf08367"	"10531"	"ENSG00000107959"	"PITRM1"	"B3KMJ6; B4E0J8; C9JSL2; E7ES23; hsa:10531; O95204; Q2M2G6; Q4VBR1; Q5JRW7; Q5JRX3; Q7L5Z7; Q9BSI6; Q9BVJ5; Q9UPP8"	""	"Mitochondrial protein import"	"1"	"0"	"615.4"	"522.4"	"655.8"	"616.8"	"638.6"	"732.5"	"1052.4"	"5980.6"	"6222.9"	"18978.2"	"28472.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P2Q9"	"Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2"	"0.000"	""	"18"	"37"	"69"	"37"	"2335"	"273.4"	"8.84"	"11119.09"	"130.76"	"28"	"34"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01398, Pf08082, Pf08083, Pf08084, Pf10596, Pf10597, Pf10598, Pf12134"	"10594"	"ENSG00000174231; ENSG00000274442"	"PRPF8"	"hsa:10594; O14547; O75965; Q6P2Q9"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"3"	"0"	"3027.4"	"2368.1"	"3003.6"	"2677.1"	"2690.3"	"2702.5"	"3604.5"	"5856.9"	"5763.1"	"18453.9"	"33487.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P31943"	"Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4"	"0.000"	""	"48"	"20"	"61"	"9"	"449"	"49.2"	"6.30"	"11044.69"	"129.66"	"14"	"17"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08080"	"3187"	"ENSG00000169045; ENSG00000284254"	"HNRNPH1"	"B3KW86; D3DWQ2; hsa:3187; P31943; Q6IBM4"	"MECP2 and associated Rett syndrome; mRNA processing; Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells"	"mRNA Splicing - Major Pathway; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA"	"6"	"13"	"4007.4"	"3874.5"	"3103.5"	"2927.2"	"2736.1"	"2900.8"	"4336.9"	"6558.5"	"6404.5"	"12153.7"	"17332.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P04406"	"Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3"	"0.000"	""	"64"	"20"	"48"	"20"	"335"	"36.0"	"8.46"	"6835.41"	"128.15"	"12"	"19"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00044, Pf02800"	"2597"	"ENSG00000111640"	"GAPDH"	"E7EUT4; hsa:2597; P00354; P04406; Q53X65"	"Cori cycle; Alzheimer's disease and miRNA effects; HIF1A and PPARG regulation of glycolysis; VEGFA-VEGFR2 signaling; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Aerobic glycolysis; 7q11.23 copy number variation syndrome; Glycolysis in senescence; Alzheimer's disease; Sildenafil treatment; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Glycolysis; Gluconeogenesis"	"16"	"0"	"2426.5"	"1917.4"	"2439.2"	"2145.4"	"1984.2"	"2122.6"	"2992.2"	"4678.1"	"4839.5"	"9539.4"	"14338.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15029"	"116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1"	"0.000"	""	"39"	"31"	"60"	"30"	"972"	"109.4"	"5.00"	"11555.35"	"125.91"	"26"	"30"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf00679, Pf03144, Pf03764, Pf14492, Pf16004"	"9343"	"ENSG00000108883"	"EFTUD2"	"B4DK30; B4DMC0; D3DX58; hsa:9343; K7EJ81; Q15029; Q9BUR0"	"mRNA processing; Ciliary landscape"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"4"	"0"	"1778.6"	"1408.9"	"1764.5"	"1585.6"	"1473.7"	"1576.8"	"2135.1"	"3983.2"	"3696.9"	"11554.5"	"20823.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09874"	"Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4"	"0.000"	""	"31"	"33"	"74"	"33"	"1014"	"113.0"	"8.88"	"16081.11"	"124.93"	"32"	"29"	"cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00533, Pf00644, Pf00645, Pf02877, Pf05406, Pf08063"	"142"	"ENSG00000143799"	"PARP1"	"B1ANJ4; hsa:142; P09874; Q8IUZ9"	"Corticotropin-releasing hormone signaling pathway; Nanoparticle triggered regulated necrosis; Fas ligand pathway and stress induction of heat shock proteins; NAD metabolism, sirtuins and aging; NAD+ metabolism; NAD+ biosynthetic pathways; Breast cancer pathway; Acute viral myocarditis; Joubert syndrome; Male infertility; Base excision repair; IL-18 signaling pathway; DNA repair pathways, full network; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Progeria-associated lipodystrophy; Primary ovarian insufficiency; A network map of Macrophage-stimulating protein (MSP) signaling"	"SUMOylation of DNA damage response and repair proteins; Downregulation of SMAD2/3:SMAD4 transcriptional activity; HDR through MMEJ (alt-NHEJ); Formation of Incision Complex in GG-NER; DNA Damage Recognition in GG-NER; vRNA Synthesis; POLB-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER"	"25"	"0"	"2628.1"	"2013.6"	"2555.9"	"2298.1"	"2255.6"	"2439.3"	"3408.7"	"10185.7"	"9719.8"	"21326.4"	"25087.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P38646"	"Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2"	"0.000"	""	"38"	"26"	"56"	"25"	"679"	"73.6"	"6.16"	"9979.03"	"121.56"	"21"	"26"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00012"	"3313"	"ENSG00000113013"	"HSPA9"	"B2RCM1; hsa:3313; P30036; P31932; P38646; Q1HB43; Q53H23; Q6GU03; Q9BWB7; Q9UC56"	"Parkin-ubiquitin proteasomal system pathway; Iron-sulfur cluster biogenesis"	"Mitochondrial protein import; Regulation of HSF1-mediated heat shock response; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Cristae formation"	"6"	"0"	"3026.1"	"2364.3"	"2977.4"	"2795.0"	"2462.6"	"2559.8"	"3524.8"	"6346.4"	"5893.0"	"11938.1"	"17362.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07814"	"Bifunctional glutamate/proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5"	"0.000"	""	"27"	"35"	"64"	"34"	"1512"	"170.5"	"7.33"	"11415.17"	"121.54"	"25"	"28"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00043, Pf00458, Pf00587, Pf00749, Pf03129, Pf03950, Pf09180"	"2058"	"ENSG00000136628"	"EPRS1"	"A0AVA9; B9EGH3; hsa:2058; P07814; Q05BP6; Q05DF8; Q5DSM1; Q5H9S5; Q6PD57; Q86X73"	"Parkinson's disease pathway; VEGFA-VEGFR2 signaling; Amino acid metabolism"	"tRNA modification in the nucleus and cytosol; Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"6"	"1"	"3394.4"	"2461.1"	"3085.7"	"3060.8"	"2850.6"	"2734.0"	"3727.9"	"7245.4"	"7045.7"	"19536.7"	"27507.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14103"	"Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1"	"0.000"	""	"43"	"23"	"67"	"20"	"355"	"38.4"	"7.81"	"12586.38"	"121.52"	"20"	"21"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08143"	"3184"	"ENSG00000138668"	"HNRNPD"	"A8K9J2; hsa:3184; P07029; Q01858; Q14100; Q14101; Q14102; Q14103; Q4W5A1; Q9UCE8; Q9UCE9"	"mRNA processing"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"3"	"5"	"3882.3"	"3854.9"	"3910.7"	"3378.3"	"3551.9"	"3152.9"	"4638.4"	"5962.2"	"5280.7"	"8693.5"	"13199.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q4VCS5"	"Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1"	"0.000"	""	"29"	"28"	"61"	"25"	"1084"	"118.0"	"7.64"	"10532.26"	"119.32"	"25"	"25"	"cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf12240"	"154796"	"ENSG00000126016"	"AMOT"	"hsa:154796; Q4VCS5; Q504X5; Q9HD27; Q9UPT1"	"VEGFA-VEGFR2 signaling; Hippo-Merlin signaling dysregulation; Pleural mesothelioma"	""	"3"	"3"	"2296.7"	"1897.1"	"2193.7"	"2185.9"	"2083.9"	"2074.9"	"2706.3"	"4117.8"	"4155.2"	"7929.8"	"10990.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13435"	"Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2"	"0.000"	""	"26"	"23"	"57"	"23"	"895"	"100.2"	"5.67"	"11572.77"	"118.91"	"21"	"20"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf02037, Pf04037, Pf04046"	"10992"	"ENSG00000087365"	"SF3B2"	"A8K485; B4DT19; hsa:10992; Q13435; Q7L4T5; Q7Z627; Q969K1; Q96CM6; Q9BWD2"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"3"	"0"	"2743.3"	"2222.7"	"2759.4"	"2538.5"	"2545.4"	"2461.0"	"3237.8"	"3845.1"	"3588.6"	"7519.4"	"11395.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12906"	"Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3"	"0.000"	""	"32"	"22"	"55"	"22"	"894"	"95.3"	"8.76"	"9867.77"	"117.22"	"16"	"20"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00035, Pf07528"	"3609"	"ENSG00000129351"	"ILF3"	"A8K6F2; G5E9M5; hsa:3609; O43409; Q12906; Q6P1X1; Q86XY7; Q99544; Q99545; Q9BZH4; Q9BZH5; Q9NQ95; Q9NQ96; Q9NQ97; Q9NQ98; Q9NQ99; Q9NQA0; Q9NQA1; Q9NQA2; Q9NRN2; Q9NRN3; Q9NRN4; Q9UMZ9; Q9UN00; Q9UN84; Q9UNA2"	""	"Regulation of CDH11 gene transcription"	"1"	"0"	"2247.5"	"1747.7"	"2427.4"	"2134.8"	"2107.0"	"2022.8"	"2773.2"	"4279.0"	"3869.6"	"8270.0"	"12621.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49792"	"E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2"	"0.000"	""	"14"	"33"	"61"	"26"	"3224"	"358.0"	"6.20"	"11904.95"	"116.97"	"28"	"27"	"protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00160, Pf00638, Pf00641, Pf12185"	"5903"	"ENSG00000153201"	"RANBP2"	"hsa:5903; P49792; Q13074; Q15280; Q53TE2; Q59FH7"	""	"HCMV Late Events; HCMV Early Events; Transcriptional regulation by small RNAs; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Signaling by ALK fusions and activated point mutants; tRNA processing in the nucleus; Separation of Sister Chromatids; Viral Messenger RNA Synthesis; SUMOylation of DNA damage response and repair proteins; Rev-mediated nuclear export of HIV RNA; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"35"	"7"	"3073.8"	"2242.3"	"2875.7"	"2877.5"	"2617.6"	"2616.7"	"3396.3"	"5874.1"	"5789.1"	"12622.4"	"16512.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P0DMV9"	"Heat shock 70 kDa protein 1B OS=Homo sapiens OX=9606 GN=HSPA1B PE=1 SV=1"	"0.000"	""	"51"	"30"	"62"	"25"	"641"	"70.0"	"5.66"	"11102.43"	"114.62"	"26"	"28"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00012"	"3303; 3304"	"ENSG00000204388; ENSG00000212866; ENSG00000224501; ENSG00000231555; ENSG00000232804"	"HSPA1B"	"B4E3B6; hsa:3303; hsa:3304; P08107; P0DMV9; P19790; Q5JQI4; Q5SP17; Q9UQL9; Q9UQM0"	"Apoptosis modulation and signaling; Parkin-ubiquitin proteasomal system pathway; MAPK signaling pathway; Apoptosis modulation by HSP70; VEGFA-VEGFR2 signaling; Measles virus infection; CKAP4 signaling pathway map"	"Regulation of HSF1-mediated heat shock response; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Neutrophil degranulation; Attenuation phase"	"12"	"0"	"2597.5"	"1800.2"	"2505.5"	"2380.2"	"2129.1"	"2375.1"	"3150.1"	"5219.0"	"5284.1"	"12388.1"	"17895.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07437"	"Tubulin beta chain OS=Homo sapiens OX=9606 GN=TUBB PE=1 SV=2"	"0.000"	""	"50"	"17"	"58"	"3"	"444"	"49.6"	"4.89"	"9759.26"	"112.61"	"14"	"17"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;other biological processes"	"non-structural extracellular;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00091, Pf03953"	"203068"	"ENSG00000183311; ENSG00000196230; ENSG00000224156; ENSG00000227739; ENSG00000229684; ENSG00000232421; ENSG00000232575; ENSG00000235067"	"TUBB"	"hsa:203068; P05218; P07437; Q8WUC1; Q9CY33"	"Alzheimer's disease and miRNA effects; Pathogenic Escherichia coli infection; Parkin-ubiquitin proteasomal system pathway; Opioid receptor pathways; Alzheimer's disease"	"Potential therapeutics for SARS; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Neutrophil degranulation"	"14"	"19"	"1582.4"	"1278.3"	"1598.0"	"1542.8"	"1282.4"	"1354.7"	"1797.3"	"3153.3"	"2997.5"	"6437.0"	"9114.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92841"	"Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2"	"0.000"	""	"33"	"23"	"64"	"17"	"729"	"80.2"	"8.27"	"12742.09"	"109.48"	"23"	"20"	"RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"10521"	"ENSG00000100201"	"DDX17"	"B1AHM0; H3BLZ8; hsa:10521; Q69YT1; Q6ICD6; Q92841"	"Novel intracellular components of RIG-I-like receptor pathway"	"SUMOylation of transcription cofactors"	"2"	"0"	"1857.4"	"1519.5"	"1830.0"	"1660.9"	"1700.3"	"1602.6"	"2186.6"	"2732.5"	"2667.5"	"5139.5"	"7224.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q93009"	"Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2"	"0.000"	""	"26"	"18"	"44"	"18"	"1102"	"128.2"	"5.55"	"9507.44"	"109.17"	"14"	"17"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00443, Pf00917, Pf12436, Pf14533"	"7874"	"ENSG00000187555"	"USP7"	"A6NMY8; B7Z815; H0Y3G8; hsa:7874; Q93009"	"Nucleotide excision repair in xeroderma pigmentosum ; Warburg effect modulated by deubiquitinating enzymes and their substrates"	"Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Ub-specific processing proteases; Regulation of TP53 Degradation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Regulation of PTEN localization"	"10"	"0"	"930.0"	"879.3"	"971.1"	"927.4"	"878.8"	"887.8"	"1184.4"	"2284.9"	"2238.5"	"6072.3"	"10772.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P12956"	"X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2"	"0.000"	""	"40"	"26"	"56"	"26"	"609"	"69.8"	"6.64"	"12641.59"	"108.61"	"24"	"23"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02037, Pf02735, Pf03730, Pf03731"	"2547"	"ENSG00000196419"	"XRCC6"	"B1AHC8; hsa:2547; P12956; Q6FG89; Q9UCQ2; Q9UCQ3"	"Non-homologous end joining; DNA repair pathways, full network; Primary ovarian insufficiency"	"Neutrophil degranulation; Cytosolic sensors of pathogen-associated DNA ; Nonhomologous End-Joining (NHEJ); 2-LTR circle formation; IRF3-mediated induction of type I IFN"	"8"	"0"	"2953.4"	"2346.2"	"2928.8"	"2641.8"	"2477.9"	"2666.6"	"3543.8"	"5181.6"	"5003.9"	"9471.0"	"13003.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P68371"	"Tubulin beta-4B chain OS=Homo sapiens OX=9606 GN=TUBB4B PE=1 SV=1"	"0.000"	""	"46"	"16"	"56"	"2"	"445"	"49.8"	"4.89"	"9362.70"	"107.93"	"13"	"16"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response"	"non-structural extracellular;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00091, Pf03953"	"10383"	"ENSG00000188229"	"TUBB4B"	"A2BFA2; hsa:10383; P05217; P68371"	"Alzheimer's disease and miRNA effects; Pathogenic Escherichia coli infection; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"MHC class II antigen presentation; COPI-mediated anterograde transport; HCMV Early Events; Neutrophil degranulation; Formation of tubulin folding intermediates by CCT/TriC; Prefoldin mediated transfer of substrate  to CCT/TriC; COPI-dependent Golgi-to-ER retrograde traffic; Recycling pathway of L1; Translocation of SLC2A4 (GLUT4) to the plasma membrane; RHO GTPases activate IQGAPs; RHO GTPases Activate Formins; Intraflagellar transport; Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane; Gap junction assembly; Resolution of Sister Chromatid Cohesion; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Recruitment of NuMA to mitotic centrosomes; Post-chaperonin tubulin folding pathway; COPI-independent Golgi-to-ER retrograde traffic; Carboxyterminal post-translational modifications of tubulin; Assembly and cell surface presentation of NMDA receptors; Activation of AMPK downstream of NMDARs; Aggrephagy; EML4 and NUDC in mitotic spindle formation; Sealing of the nuclear envelope (NE) by ESCRT-III; Kinesins; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Hedgehog 'off' state"	"41"	"0"	"109.5"	"100.5"	"94.5"	"96.8"	"87.0"	"88.1"	"129.7"	"192.2"	"188.1"	"360.5"	"505.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P10809"	"60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2"	"0.000"	""	"37"	"24"	"57"	"24"	"573"	"61.0"	"5.87"	"10821.25"	"107.85"	"22"	"23"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00118"	"3329"	"ENSG00000144381"	"HSPD1"	"B2R5M6; B7Z712; hsa:3329; P10809; Q38L19; Q9UCR6"	"Apoptosis-related network due to altered Notch3 in ovarian cancer; 8p23.1 copy number variation syndrome; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Mitochondrial protein import; TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"	"5"	"0"	"3077.2"	"2169.6"	"2962.4"	"2675.6"	"2438.0"	"2485.1"	"3446.3"	"5512.8"	"5290.0"	"11949.8"	"23230.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08238"	"Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4"	"0.000"	""	"38"	"25"	"50"	"12"	"724"	"83.2"	"5.03"	"8255.15"	"107.10"	"18"	"24"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00183, Pf02518"	"3326"	"ENSG00000096384"	"HSP90AB1"	"B2R5P0; hsa:3326; P08238; Q5T9W7; Q9NQW0; Q9NTK6"	"Nuclear receptors meta-pathway; NRF2 pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway"	"Potential therapeutics for SARS; Regulation of actin dynamics for phagocytic cup formation; The role of GTSE1 in G2/M progression after G2 checkpoint; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Aryl hydrocarbon receptor signalling; Neutrophil degranulation; Estrogen-dependent gene expression; Sema3A PAK dependent Axon repulsion; DDX58/IFIH1-mediated induction of interferon-alpha/beta; The NLRP3 inflammasome; Purinergic signaling in leishmaniasis infection; RHOBTB2 GTPase cycle; Chaperone Mediated Autophagy; HSF1 activation; Attenuation phase; Uptake and function of diphtheria toxin"	"23"	"13"	"2364.2"	"1665.3"	"2248.8"	"2076.4"	"1868.7"	"1976.0"	"2669.1"	"4146.2"	"4074.0"	"8361.8"	"12365.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7KZ85"	"Transcription elongation factor SPT6 OS=Homo sapiens OX=9606 GN=SUPT6H PE=1 SV=2"	"0.000"	""	"21"	"30"	"54"	"30"	"1726"	"198.9"	"4.91"	"9768.99"	"106.68"	"23"	"25"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00575, Pf14632, Pf14633, Pf14635, Pf14639, Pf14641, Pf17674"	"6830"	"ENSG00000109111"	"SUPT6H"	"A7E2B4; hsa:6830; Q15737; Q6GMQ4; Q7KYW9; Q7KZ85; Q7LDK4; Q8N526; Q92775; Q96AH3; Q9BTH9; Q9BTI2"	""	"Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events"	"3"	"0"	"3069.3"	"2472.3"	"3275.2"	"3046.7"	"2731.1"	"2759.4"	"3716.2"	"4747.6"	"4432.1"	"7067.6"	"9286.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75533"	"Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3"	"0.000"	""	"17"	"22"	"53"	"22"	"1304"	"145.7"	"7.09"	"9976.93"	"104.98"	"20"	"19"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf08920"	"23451"	"ENSG00000115524"	"SF3B1"	"E9PCH3; hsa:23451; O75533"	"mRNA processing; 10q11.21q11.23 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression; mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"5"	"0"	"2978.5"	"2161.3"	"3024.2"	"2914.9"	"2812.1"	"2825.6"	"3691.6"	"4625.0"	"4531.6"	"9494.0"	"15083.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2L1"	"Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2"	"0.000"	""	"27"	"24"	"50"	"24"	"958"	"108.9"	"7.14"	"9432.74"	"102.44"	"21"	"21"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00773, Pf13638, Pf17215, Pf17216, Pf17849"	"22894"	"ENSG00000083520"	"DIS3"	"A6NI21; B2RBL2; hsa:22894; Q5W0P7; Q5W0P8; Q658Z7; Q7Z481; Q8WWI2; Q9UG36; Q9Y2L1"	""	"ATF4 activates genes in response to endoplasmic reticulum  stress; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; Major pathway of rRNA processing in the nucleolus and cytosol; KSRP (KHSRP) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	"6"	"0"	"1189.5"	"923.1"	"1145.7"	"1097.0"	"1028.7"	"1060.7"	"1474.9"	"4413.9"	"4545.8"	"9506.9"	"11307.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35579"	"Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4"	"0.000"	""	"18"	"28"	"47"	"24"	"1960"	"226.4"	"5.60"	"8970.53"	"101.48"	"21"	"25"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00063, Pf01576, Pf02736"	"4627"	"ENSG00000100345"	"MYH9"	"A8K6E4; hsa:4627; O60805; P35579; Q60FE2; Q86T83"	"Primary focal segmental glomerulosclerosis (FSGS); VEGFA-VEGFR2 signaling; Nephrotic syndrome"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Signaling by ALK fusions and activated point mutants; RHO GTPases activate CIT; EPHA-mediated growth cone collapse; Sema4D induced cell migration and growth-cone collapse; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; RHO GTPases activate PAKs; CD163 mediating an anti-inflammatory response"	"16"	"4"	"841.2"	"603.9"	"933.8"	"828.0"	"773.4"	"789.3"	"998.4"	"1730.8"	"1718.9"	"7307.8"	"14030.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14979"	"Heterogeneous nuclear ribonucleoprotein D-like OS=Homo sapiens OX=9606 GN=HNRNPDL PE=1 SV=3"	"0.000"	""	"33"	"16"	"53"	"14"	"420"	"46.4"	"9.57"	"12150.15"	"100.67"	"16"	"15"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity"	"Pf00076"	"9987"	"ENSG00000152795"	"HNRNPDL"	"hsa:9987; O14979; Q6SPF2; Q7KZ74; Q7KZ75; Q96IM0; Q96S43"	""	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	"1"	"0"	"2421.5"	"2040.3"	"2164.0"	"2044.9"	"2062.6"	"1708.3"	"2542.5"	"3248.4"	"2843.3"	"4756.9"	"6758.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15459"	"Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1"	"0.000"	""	"29"	"19"	"43"	"19"	"793"	"88.8"	"5.22"	"10021.76"	"100.11"	"17"	"18"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00240, Pf01805, Pf12230"	"10291"	"ENSG00000099995"	"SF3A1"	"E9PAW1; hsa:10291; Q15459"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"1139.6"	"960.4"	"1109.5"	"1062.7"	"1052.1"	"1053.3"	"1384.6"	"3110.2"	"3053.4"	"8489.0"	"12714.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22102"	"Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1"	"0.000"	""	"30"	"28"	"51"	"28"	"1010"	"107.7"	"6.70"	"9832.66"	"99.45"	"24"	"25"	"other metabolic processes;developmental processes;other biological processes"	"cytosol"	"other molecular function"	"Pf00551, Pf00586, Pf01071, Pf02769, Pf02843, Pf02844"	"2618"	"ENSG00000159131; ENSG00000262473"	"GART"	"A8K945; A8KA32; D3DSF3; D3DSF4; hsa:2618; O14659; P22102; Q52M77"	"Folate metabolism; One-carbon metabolism; Metabolic reprogramming in colon cancer"	"Purine ribonucleoside monophosphate biosynthesis"	"4"	"0"	"791.7"	"643.4"	"778.0"	"754.7"	"781.8"	"1323.3"	"2305.2"	"5031.2"	"5089.6"	"13316.7"	"20464.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09651"	"Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5"	"0.000"	""	"36"	"17"	"46"	"14"	"372"	"38.7"	"9.13"	"8963.37"	"98.64"	"12"	"14"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf11627"	"3178"	"ENSG00000135486"	"HNRNPA1"	"A8K4Z8; hsa:3178; P09651; Q3MIB7; Q6PJZ7"	"mRNA processing"	"mRNA Splicing - Major Pathway; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA; SARS-CoV-1-host interactions; SARS-CoV-1 modulates host translation machinery"	"6"	"0"	"2719.4"	"2836.7"	"2674.7"	"2227.3"	"2362.6"	"2359.7"	"3033.0"	"3635.6"	"3037.5"	"4850.9"	"7207.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UQ80"	"Proliferation-associated protein 2G4 OS=Homo sapiens OX=9606 GN=PA2G4 PE=1 SV=3"	"0.000"	""	"49"	"20"	"52"	"19"	"394"	"43.8"	"6.55"	"10053.27"	"97.93"	"18"	"17"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"non-structural extracellular;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00557"	"5036"	"ENSG00000170515"	"PA2G4"	"hsa:5036; O43846; Q9UM59; Q9UQ80"	""	"Neutrophil degranulation"	"1"	"1"	"1465.7"	"1021.3"	"1387.3"	"1222.2"	"1133.6"	"1367.7"	"1833.6"	"7289.3"	"7523.0"	"14355.7"	"14232.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42285"	"Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3"	"0.000"	""	"24"	"23"	"51"	"23"	"1042"	"117.7"	"6.52"	"8803.69"	"97.21"	"20"	"21"	"RNA metabolism OR transcription;other metabolic processes;stress response"	"nucleus"	"other molecular function"	"Pf00270, Pf00271, Pf08148, Pf13234"	"23517"	"ENSG00000039123"	"MTREX"	"hsa:23517; P42285; Q2M386; Q6MZZ8; Q6P170; Q8N5R0; Q8TAG2"	""	"mRNA Splicing - Major Pathway; Major pathway of rRNA processing in the nucleolus and cytosol"	"2"	"0"	"1566.3"	"1179.4"	"1649.6"	"1511.8"	"1352.4"	"1513.8"	"2112.8"	"4575.5"	"4693.2"	"11853.4"	"16962.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14866"	"Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2"	"0.000"	""	"36"	"14"	"45"	"13"	"589"	"64.1"	"8.22"	"9022.76"	"96.38"	"10"	"14"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf11835, Pf13893"	"3191"	"ENSG00000104824; ENSG00000282947"	"HNRNPL"	"A6ND69; A6NIT8; hsa:3191; P14866; Q9H3P3"	"mRNA processing; Hippocampal synaptogenesis and neurogenesis"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"4"	"1"	"2580.3"	"2327.9"	"2377.7"	"2257.7"	"2173.8"	"1995.1"	"2839.9"	"3772.2"	"3208.1"	"5381.3"	"8434.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50991"	"T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4"	"0.000"	""	"42"	"16"	"36"	"16"	"539"	"57.9"	"7.83"	"5969.02"	"94.98"	"9"	"15"	"protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00118"	"10575"	"ENSG00000115484"	"CCT4"	"B2R6I3; B7Z8B1; F5H5W3; hsa:10575; O14870; P50991; Q53QP9; Q96C51"	"16p11.2 proximal deletion syndrome"	"Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; Folding of actin by CCT/TriC"	"7"	"0"	"860.0"	"657.1"	"841.8"	"781.1"	"729.0"	"781.7"	"1001.7"	"2284.5"	"2490.9"	"10179.1"	"21656.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P00558"	"Phosphoglycerate kinase 1 OS=Homo sapiens OX=9606 GN=PGK1 PE=1 SV=3"	"0.000"	""	"50"	"20"	"40"	"20"	"417"	"44.6"	"8.10"	"7160.65"	"94.58"	"13"	"16"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;other membranes;cytosol"	"kinase activity;other molecular function"	"Pf00162"	"5230"	"ENSG00000102144"	"PGK1"	"A8K4W6; B7Z7A9; hsa:5230; P00558; Q5J7W1; Q6IBT6; Q8NI87"	"Cori cycle; Photodynamic therapy-induced HIF-1 survival signaling; VEGFA-VEGFR2 signaling; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Aerobic glycolysis; Glycolysis in senescence; Warburg effect modulated by deubiquitinating enzymes and their substrates; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"Glycolysis; Gluconeogenesis; Manipulation of host energy metabolism"	"13"	"0"	"437.8"	"352.0"	"489.2"	"444.4"	"404.2"	"406.9"	"565.1"	"3742.1"	"3851.5"	"19759.2"	"30618.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y383"	"Putative RNA-binding protein Luc7-like 2 OS=Homo sapiens OX=9606 GN=LUC7L2 PE=1 SV=2"	"0.000"	""	"40"	"16"	"47"	"12"	"392"	"46.5"	"10.01"	"8779.05"	"94.54"	"14"	"16"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03194"	"51631"	"ENSG00000146963"	"LUC7L2"	"B7Z500; hsa:51631; Q8IUP9; Q9NVL3; Q9NVN7; Q9UQN1; Q9Y383"	""	""	"0"	"7"	"1135.9"	"845.7"	"1187.8"	"1061.7"	"1020.9"	"1052.1"	"1431.5"	"4013.4"	"3913.9"	"11399.3"	"14946.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99459"	"Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2"	"0.000"	""	"32"	"25"	"53"	"25"	"802"	"92.2"	"8.18"	"10828.24"	"94.46"	"22"	"18"	"cell cycle OR cell proliferation;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf11831, Pf13921"	"988"	"ENSG00000096401"	"CDC5L"	"hsa:988; Q76N46; Q99459; Q99974"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"1609.5"	"1251.0"	"1574.0"	"1428.1"	"1415.2"	"1566.3"	"2155.3"	"6313.1"	"6274.5"	"18353.8"	"23051.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q01081"	"Splicing factor U2AF 35 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF1 PE=1 SV=3"	"0.000"	""	"48"	"11"	"30"	"11"	"240"	"27.9"	"8.81"	"4721.77"	"94.29"	"5"	"11"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00642"	"102724594; 7307"	"ENSG00000160201"	"U2AF1"	"hsa:102724594; hsa:7307; Q01081; Q701P4; Q71RF1"	"mRNA processing"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript"	"5"	"0"	"479.2"	"395.0"	"425.5"	"417.6"	"395.3"	"325.0"	"542.4"	"1833.5"	"2129.0"	"5982.1"	"7786.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q07157"	"Tight junction protein ZO-1 OS=Homo sapiens OX=9606 GN=TJP1 PE=1 SV=3"	"0.000"	""	"16"	"22"	"46"	"22"	"1748"	"195.3"	"6.70"	"9819.39"	"93.63"	"22"	"22"	"cell adhesion;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00595, Pf00625, Pf00791, Pf07653"	"7082"	"ENSG00000104067; ENSG00000277401"	"TJP1"	"B4E3K1; hsa:7082; Q07157; Q2NKP3; Q4ZGJ6"	"Epithelial to mesenchymal transition in colorectal cancer; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Gastrin signaling pathway; Disruption of postsynaptic signaling by CNV; 1q21.1 copy number variation syndrome; CKAP4 signaling pathway map; 15q11q13 copy number variation"	"RUNX1 regulates expression of components of tight junctions; Signaling by Hippo; Regulation of gap junction activity; SARS-CoV-2 targets PDZ proteins in cell-cell junction; Apoptotic cleavage of cell adhesion  proteins"	"12"	"0"	"1545.7"	"1359.8"	"1583.9"	"1482.1"	"1485.5"	"1451.7"	"1906.8"	"4350.1"	"4216.8"	"10112.1"	"11291.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P68363"	"Tubulin alpha-1B chain OS=Homo sapiens OX=9606 GN=TUBA1B PE=1 SV=1"	"0.000"	""	"43"	"16"	"38"	"2"	"451"	"50.1"	"5.06"	"6194.83"	"91.91"	"11"	"16"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00091, Pf03953"	"10376"	"ENSG00000123416"	"TUBA1B"	"hsa:10376; P04687; P05209; P68363; Q27I68; Q8WU19"	"Alzheimer's disease and miRNA effects; Pathogenic Escherichia coli infection; Allograft rejection; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"HCMV Early Events; RHO GTPases Activate Formins; Intraflagellar transport; Recycling pathway of L1; COPI-dependent Golgi-to-ER retrograde traffic; Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane; Gap junction assembly; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Recruitment of NuMA to mitotic centrosomes; Formation of tubulin folding intermediates by CCT/TriC; Post-chaperonin tubulin folding pathway; RHO GTPases activate IQGAPs; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Carboxyterminal post-translational modifications of tubulin; Assembly and cell surface presentation of NMDA receptors; Activation of AMPK downstream of NMDARs; Aggrephagy; EML4 and NUDC in mitotic spindle formation; Sealing of the nuclear envelope (NE) by ESCRT-III; Kinesins; Hedgehog 'off' state; RHOH GTPase cycle"	"35"	"13"	"1479.1"	"1305.4"	"1316.2"	"1317.9"	"1136.1"	"1300.8"	"1718.6"	"2708.1"	"2780.2"	"6310.2"	"9687.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60506"	"Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2"	"0.000"	""	"37"	"20"	"51"	"10"	"623"	"69.6"	"8.59"	"8601.26"	"89.68"	"17"	"19"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf18360"	"10492"	"ENSG00000135316"	"SYNCRIP"	"E1P501; E1P502; hsa:10492; O60506; Q53H05; Q5TCG2; Q5TCG3; Q8IW78; Q8N599; Q96LC1; Q96LC2; Q9Y583"	""	""	"0"	"0"	"1402.8"	"1178.6"	"1452.0"	"1246.0"	"1225.7"	"1252.5"	"1645.0"	"2292.2"	"2231.1"	"4864.2"	"7584.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P78371"	"T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4"	"0.000"	""	"33"	"15"	"37"	"15"	"535"	"57.5"	"6.46"	"7907.66"	"88.66"	"9"	"13"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00118"	"10576"	"ENSG00000166226"	"CCT2"	"A8K402; B5BTY7; B7Z243; B7Z7K4; B7ZAT2; hsa:10576; P78371; Q14D36; Q6IAT3"	"16p11.2 proximal deletion syndrome"	"Neutrophil degranulation; Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle; Folding of actin by CCT/TriC"	"10"	"0"	"410.7"	"341.2"	"430.6"	"396.5"	"348.1"	"377.6"	"485.4"	"1064.4"	"1104.0"	"5213.8"	"12392.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23246"	"Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2"	"0.000"	""	"27"	"22"	"50"	"21"	"707"	"76.1"	"9.44"	"9643.60"	"88.03"	"19"	"19"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08075"	"6421"	"ENSG00000116560"	"SFPQ"	"hsa:6421; P23246; P30808; Q5SZ71"	"mRNA processing; Type 2 papillary renal cell carcinoma"	"Suppression of apoptosis; PTK6 Regulates Proteins Involved in RNA Processing"	"4"	"1"	"3745.4"	"2999.0"	"3535.7"	"3282.3"	"3287.6"	"3283.2"	"4451.8"	"5398.8"	"5235.8"	"8605.8"	"12315.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52272"	"Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3"	"0.000"	""	"32"	"21"	"40"	"21"	"730"	"77.5"	"8.70"	"7324.75"	"87.99"	"19"	"16"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf11532"	"4670"	"ENSG00000099783"	"HNRNPM"	"hsa:4670; P52272; Q15584; Q8WZ44; Q96H56; Q9BWL9; Q9Y492"	"mRNA processing"	"Processing of Capped Intron-Containing Pre-mRNA; mRNA Splicing - Major Pathway; FGFR2 alternative splicing"	"4"	"0"	"2164.6"	"1602.5"	"2222.0"	"2023.8"	"1988.2"	"2014.7"	"2874.9"	"4436.0"	"4263.2"	"9666.8"	"14283.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22234"	"Multifunctional protein ADE2 OS=Homo sapiens OX=9606 GN=PAICS PE=1 SV=3"	"0.000"	""	"34"	"17"	"43"	"17"	"425"	"47.0"	"7.23"	"8070.05"	"87.91"	"13"	"15"	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00731, Pf01259"	"10606"	"ENSG00000128050"	"PAICS"	"E9PDH9; hsa:10606; P22234; Q68CQ5"	"Metabolic reprogramming in colon cancer"	"Purine ribonucleoside monophosphate biosynthesis"	"2"	"0"	"953.1"	"764.6"	"952.5"	"881.2"	"861.8"	"782.8"	"1105.7"	"2649.4"	"2842.0"	"9538.8"	"13404.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11021"	"Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2"	"0.000"	""	"39"	"24"	"47"	"22"	"654"	"72.3"	"5.16"	"10025.10"	"87.91"	"22"	"20"	"protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;nucleus;other cell component"	"translation activity;other molecular function"	"Pf00012"	"3309"	"ENSG00000044574"	"HSPA5"	"B0QZ61; hsa:3309; P11021; Q2EF78; Q9NPF1; Q9UK02"	"Parkin-ubiquitin proteasomal system pathway; Apoptosis-related network due to altered Notch3 in ovarian cancer; Photodynamic therapy-induced unfolded protein response; Prion disease pathway; Unfolded protein response; Orexin receptor pathway"	"Regulation of HSF1-mediated heat shock response; Platelet degranulation ; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; ATF6B (ATF6-beta) activates chaperones; IRE1alpha activates chaperones; PERK regulates gene expression; ATF6 (ATF6-alpha) activates chaperone genes"	"14"	"0"	"1788.7"	"1406.0"	"1726.6"	"1606.3"	"1494.6"	"1649.8"	"2172.8"	"3844.8"	"3794.6"	"9153.2"	"13748.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50990"	"T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4"	"0.000"	""	"37"	"19"	"38"	"19"	"548"	"59.6"	"5.60"	"7184.31"	"86.95"	"14"	"18"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00118"	"10694"	"ENSG00000156261"	"CCT8"	"A6NN54; B4DEM7; B4DQH4; hsa:10694; P50990; Q4VBP8"	"16p11.2 proximal deletion syndrome"	"Association of TriC/CCT with target proteins during biosynthesis; Neutrophil degranulation; Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; Folding of actin by CCT/TriC"	"8"	"0"	"804.3"	"595.5"	"875.1"	"811.1"	"742.7"	"762.1"	"1032.9"	"2378.7"	"2261.5"	"10890.1"	"23929.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HB71"	"Calcyclin-binding protein OS=Homo sapiens OX=9606 GN=CACYBP PE=1 SV=2"	"0.000"	""	"50"	"16"	"46"	"15"	"228"	"26.2"	"8.25"	"10518.55"	"86.80"	"15"	"13"	"developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf04969, Pf05002, Pf09032"	"27101"	"ENSG00000116161"	"CACYBP"	"B2ZWH2; B3KSF1; hsa:27101; O60666; Q5R370; Q5R371; Q9HB71"	"Gastric cancer network 2"	""	"1"	"1"	"954.3"	"783.6"	"898.3"	"854.9"	"924.3"	"1337.7"	"2217.7"	"6300.6"	"6025.3"	"11392.5"	"18740.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60216"	"Double-strand-break repair protein rad21 homolog OS=Homo sapiens OX=9606 GN=RAD21 PE=1 SV=2"	"0.000"	""	"30"	"16"	"34"	"16"	"631"	"71.6"	"4.65"	"5071.40"	"86.62"	"9"	"15"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04824, Pf04825"	"5885"	"ENSG00000164754"	"RAD21"	"A8K0E0; hsa:5885; O60216; Q15001; Q99568"	"Cell cycle; Prion disease pathway; Regulation of sister chromatid separation at the metaphase-anaphase transition; Cohesin complex - Cornelia de Lange syndrome; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; 10q22q23 copy number variation"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Meiotic synapsis; SUMOylation of DNA damage response and repair proteins; Estrogen-dependent gene expression; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"13"	"0"	"1263.6"	"1003.9"	"1173.6"	"1101.8"	"1056.5"	"1139.3"	"1453.9"	"2324.8"	"2216.2"	"5107.1"	"7347.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19338"	"Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3"	"0.000"	""	"37"	"34"	"62"	"34"	"710"	"76.6"	"4.70"	"12355.12"	"86.34"	"30"	"24"	"developmental processes;other biological processes"	"plasma membrane;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"4691"	"ENSG00000115053"	"NCL"	"hsa:4691; P19338; Q53SK1; Q8NB06; Q9UCF0; Q9UDG1"	"Pathogenic Escherichia coli infection; VEGFA-VEGFR2 signaling"	"Major pathway of rRNA processing in the nucleolus and cytosol"	"3"	"0"	"6697.5"	"5256.0"	"5685.5"	"5628.1"	"5457.9"	"5428.7"	"7153.9"	"9705.0"	"9125.6"	"15184.0"	"17958.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63241"	"Eukaryotic translation initiation factor 5A-1 OS=Homo sapiens OX=9606 GN=EIF5A PE=1 SV=2"	"0.000"	""	"60"	"7"	"40"	"7"	"154"	"16.8"	"5.24"	"6799.61"	"86.01"	"4"	"7"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf01287"	"1984"	"ENSG00000132507; ENSG00000288145"	"EIF5A"	"A8K9A0; D3DTP2; hsa:1984; P10159; P63241; Q16182; Q7L7L3; Q7Z4L1; Q9D0G2"	"Translation factors; eIF5A regulation in response to inhibition of the nuclear export system"	"Hypusine synthesis from eIF5A-lysine"	"3"	"0"	"337.2"	"254.1"	"374.7"	"362.9"	"355.9"	"384.8"	"584.8"	"4056.9"	"4263.4"	"11032.4"	"14557.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q71U36"	"Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1"	"0.000"	""	"43"	"16"	"35"	"2"	"451"	"50.1"	"5.06"	"5799.30"	"85.36"	"11"	"16"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00091, Pf03953"	"7846"	"ENSG00000167552"	"TUBA1A"	"A8K0B8; G3V1U9; hsa:7846; P04687; P05209; Q71U36"	"Alzheimer's disease and miRNA effects; Pathogenic Escherichia coli infection; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease; PAFAH1B1 copy number variation"	"COPI-dependent Golgi-to-ER retrograde traffic; Separation of Sister Chromatids; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Kinesins; The role of GTSE1 in G2/M progression after G2 checkpoint; RHO GTPases activate IQGAPs; HCMV Early Events; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Recycling pathway of L1; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; COPI-mediated anterograde transport; Sealing of the nuclear envelope (NE) by ESCRT-III; Hedgehog 'off' state; Intraflagellar transport; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane; Gap junction assembly; Formation of tubulin folding intermediates by CCT/TriC; Post-chaperonin tubulin folding pathway; COPI-independent Golgi-to-ER retrograde traffic; Carboxyterminal post-translational modifications of tubulin; Assembly and cell surface presentation of NMDA receptors; Activation of AMPK downstream of NMDARs; Aggrephagy; Prefoldin mediated transfer of substrate  to CCT/TriC"	"41"	"0"	"49.7"	"25.6"	"54.2"	"61.8"	"43.9"	"37.3"	"62.7"	"109.8"	"124.3"	"299.1"	"447.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13010"	"X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3"	"0.000"	""	"31"	"21"	"45"	"21"	"732"	"82.7"	"5.81"	"7439.26"	"84.67"	"17"	"19"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf02735, Pf03730, Pf03731, Pf08785"	"7520"	"ENSG00000079246"	"XRCC5"	"A8K3X5; hsa:7520; P13010; Q0Z7V0; Q4VBQ5; Q53HH7; Q7M4N0; Q9UCQ0; Q9UCQ1"	"Non-homologous end joining; Male infertility; DNA repair pathways, full network; p53 transcriptional gene network"	"Neutrophil degranulation; Cytosolic sensors of pathogen-associated DNA ; Nonhomologous End-Joining (NHEJ); 2-LTR circle formation; IRF3-mediated induction of type I IFN"	"9"	"0"	"1672.9"	"1364.7"	"1635.7"	"1560.4"	"1480.4"	"1557.7"	"2070.7"	"3102.5"	"2990.6"	"6444.9"	"9475.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P21333"	"Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4"	"0.000"	""	"12"	"23"	"37"	"22"	"2647"	"280.6"	"6.06"	"6102.77"	"84.62"	"15"	"22"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00307, Pf00630"	"2316"	"ENSG00000196924"	"FLNA"	"E9KL45; hsa:2316; P21333; Q5HY53; Q5HY55; Q8NF52"	"Androgen receptor signaling pathway; Prolactin signaling pathway; Focal adhesion; Hypothesized pathways in pathogenesis of cardiovascular disease; MAPK signaling pathway; IL-4 signaling pathway; Ebola virus infection in host; Joubert syndrome; NPHP1 deletion syndrome"	"OAS antiviral response; Platelet degranulation ; RHO GTPases activate PAKs; GP1b-IX-V activation signalling; Cell-extracellular matrix interactions"	"14"	"1"	"890.3"	"695.1"	"950.4"	"852.2"	"757.9"	"795.1"	"1026.1"	"1904.5"	"1858.5"	"7929.2"	"13165.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49750"	"YLP motif-containing protein 1 OS=Homo sapiens OX=9606 GN=YLPM1 PE=1 SV=4"	"0.000"	""	"11"	"22"	"37"	"22"	"2146"	"241.5"	"6.55"	"5677.74"	"83.31"	"16"	"21"	"other biological processes"	"cytosol;nucleus"	""	"Pf13671"	"56252"	"ENSG00000119596"	"YLPM1"	"hsa:56252; P49750; P49752; Q96I64; Q9P1V7"	""	""	"0"	"0"	"2576.3"	"2063.5"	"2351.7"	"2350.3"	"2070.8"	"2182.0"	"2787.6"	"3602.6"	"3595.7"	"5829.9"	"6841.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14618"	"Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4"	"0.000"	""	"39"	"16"	"34"	"16"	"531"	"57.9"	"7.84"	"7355.94"	"82.32"	"13"	"14"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00224, Pf02887"	"5315"	"ENSG00000067225"	"PKM"	"A6NFK3; B2R5N8; B3KRY0; B4DFX8; B4DUU6; hsa:5315; P14618; P14786; Q53GK4; Q96E76; Q9BWB5; Q9UCV6; Q9UPF2"	"Photodynamic therapy-induced HIF-1 survival signaling; Amino acid metabolism; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Aerobic glycolysis; Glycolysis in senescence; Glucose metabolism in triple-negative breast cancer cells; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"Neutrophil degranulation"	"10"	"0"	"1000.6"	"726.9"	"975.5"	"910.3"	"865.9"	"774.5"	"1194.5"	"2141.9"	"2127.9"	"7045.9"	"13783.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P04075"	"Fructose-bisphosphate aldolase A OS=Homo sapiens OX=9606 GN=ALDOA PE=1 SV=2"	"0.000"	""	"49"	"22"	"47"	"18"	"364"	"39.4"	"8.09"	"10093.20"	"81.67"	"21"	"18"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00274"	"226"	"ENSG00000149925"	"ALDOA"	"B4DXI7; hsa:226; P04075; Q6FH76; Q6FI10; Q96B15; Q9BWD9; Q9UCN2"	"VEGFA-VEGFR2 signaling; Clear cell renal cell carcinoma pathways; Aerobic glycolysis; 16p11.2 proximal deletion syndrome; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Glycolysis; Gluconeogenesis; Neutrophil degranulation; Platelet degranulation"	"11"	"4"	"3217.9"	"2303.2"	"2562.2"	"2215.9"	"2404.9"	"2417.3"	"3336.8"	"5030.2"	"4423.9"	"8583.6"	"14303.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P06733"	"Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2"	"0.000"	""	"38"	"17"	"36"	"17"	"434"	"47.1"	"7.39"	"6979.20"	"81.43"	"13"	"17"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00113, Pf03952"	"2023"	"ENSG00000074800"	"ENO1"	"B2RD59; hsa:2023; P06733; P22712; Q16704; Q4TUS4; Q53FT9; Q53HR3; Q658M5; Q6GMP2; Q71V37; Q7Z3V6; Q8WU71; Q96GV1; Q9BT62; Q9UCH6; Q9UM55"	"Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Aerobic glycolysis; IL-18 signaling pathway; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"Glycolysis; Gluconeogenesis; Manipulation of host energy metabolism"	"9"	"0"	"654.6"	"426.6"	"797.7"	"675.5"	"640.3"	"628.3"	"851.1"	"3172.4"	"3811.3"	"10813.8"	"17682.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46013"	"Proliferation marker protein Ki-67 OS=Homo sapiens OX=9606 GN=MKI67 PE=1 SV=2"	"0.000"	""	"11"	"28"	"51"	"27"	"3256"	"358.5"	"9.45"	"10806.26"	"81.37"	"28"	"23"	"cell cycle OR cell proliferation;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00498, Pf08065, Pf15276"	"4288"	"ENSG00000148773"	"MKI67"	"hsa:4288; P46013; Q5VWH2"	"Primary focal segmental glomerulosclerosis (FSGS)"	""	"1"	"1"	"2628.1"	"2526.1"	"2618.4"	"2560.5"	"2660.2"	"2620.7"	"3365.9"	"4083.3"	"3862.9"	"5540.7"	"6617.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P40926"	"Malate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=MDH2 PE=1 SV=3"	"0.000"	""	"52"	"14"	"44"	"14"	"338"	"35.5"	"8.68"	"7856.11"	"81.32"	"13"	"13"	"other metabolic processes"	"other membranes;mitochondrion;other cell component"	"other molecular function"	"Pf00056, Pf02866"	"4191"	"ENSG00000146701"	"MDH2"	"A8K414; B2RE78; B4DE44; E9PDB2; hsa:4191; O43682; P40926"	"Amino acid metabolism; Metabolic reprogramming in colon cancer; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders; TCA cycle (aka Krebs or citric acid cycle)"	"Gluconeogenesis; Citric acid cycle (TCA cycle)"	"8"	"0"	"2087.8"	"1973.8"	"1959.5"	"1770.7"	"1821.2"	"1800.4"	"2240.5"	"5035.6"	"5151.4"	"11075.9"	"11675.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55795"	"Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1"	"0.000"	""	"35"	"15"	"41"	"6"	"449"	"49.2"	"6.30"	"7344.81"	"81.14"	"12"	"13"	"other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf00076, Pf08080"	"3188"	"ENSG00000126945"	"HNRNPH2"	"A1L400; hsa:3188; P55795; Q9HHA7"	"mRNA processing"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"3"	"0"	"574.5"	"348.5"	"502.4"	"459.5"	"432.5"	"378.4"	"656.9"	"969.7"	"919.7"	"1649.3"	"2441.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P17987"	"T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1"	"0.000"	""	"43"	"18"	"35"	"18"	"556"	"60.3"	"6.11"	"5834.41"	"80.91"	"11"	"17"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf00118"	"6950"	"ENSG00000120438"	"TCP1"	"E1P5B2; hsa:6950; P17987; Q15556; Q5TCM3"	"16p11.2 proximal deletion syndrome"	"Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; Folding of actin by CCT/TriC"	"8"	"0"	"575.6"	"417.4"	"584.1"	"517.6"	"486.2"	"530.8"	"689.6"	"1844.0"	"2099.5"	"8230.1"	"16258.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15393"	"Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4"	"0.000"	""	"19"	"20"	"39"	"20"	"1217"	"135.5"	"5.26"	"6829.89"	"80.16"	"17"	"20"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03178, Pf10433"	"23450"	"ENSG00000189091"	"SF3B3"	"hsa:23450; Q15393; Q6NTI8; Q96GC0; Q9BPY2; Q9UFX7; Q9UJ29"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"3"	"0"	"1517.9"	"1065.4"	"1489.9"	"1327.3"	"1341.5"	"1372.8"	"1871.3"	"3220.3"	"3084.1"	"8659.0"	"15842.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51991"	"Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2"	"0.000"	""	"41"	"17"	"46"	"15"	"378"	"39.6"	"9.01"	"9634.83"	"80.09"	"13"	"16"	"RNA metabolism OR transcription;other metabolic processes;transport"	"nucleus;other cell component"	"transporter activity;nucleic acid binding activity"	"Pf00076"	"220988"	"ENSG00000170144"	"HNRNPA3"	"D3DPF4; hsa:220988; P51991; Q53RW7; Q6URK5"	""	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"2"	"0"	"2117.9"	"2110.7"	"1995.0"	"1909.0"	"1965.1"	"1898.1"	"2559.0"	"3141.4"	"2792.4"	"4673.3"	"6822.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P48643"	"T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1"	"0.000"	""	"33"	"18"	"31"	"18"	"541"	"59.6"	"5.66"	"6522.99"	"80.04"	"10"	"15"	"protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00118"	"22948"	"ENSG00000150753"	"CCT5"	"A8JZY8; A8K2X8; B4DYD8; hsa:22948; P48643"	"16p11.2 proximal deletion syndrome"	"Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; Folding of actin by CCT/TriC"	"7"	"0"	"925.3"	"720.8"	"944.7"	"913.7"	"819.0"	"862.2"	"1136.9"	"2451.1"	"2398.5"	"10382.9"	"22920.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P60891"	"Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2"	"0.000"	""	"55"	"17"	"40"	"7"	"318"	"34.8"	"6.98"	"8386.63"	"79.50"	"15"	"15"	"other metabolic processes;developmental processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf13793, Pf14572"	"5631"	"ENSG00000147224"	"PRPS1"	"B1ALA8; B2R6T7; B4DNL6; D3DUX6; hsa:5631; P09329; P60891"	""	"5-Phosphoribose 1-diphosphate biosynthesis"	"1"	"11"	"1618.4"	"1456.5"	"1706.3"	"1599.4"	"1374.4"	"1490.8"	"2018.1"	"4463.5"	"4224.4"	"9757.6"	"13668.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P17844"	"Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1"	"0.000"	""	"39"	"26"	"48"	"20"	"614"	"69.1"	"8.92"	"9162.37"	"79.45"	"23"	"21"	"RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf08061"	"1655"	"ENSG00000108654"	"DDX5"	"B4DLW8; B5BU21; D3DU32; E7ETL9; hsa:1655; O75681; P17844; Q53Y61"	"Ciliary landscape"	"Estrogen-dependent gene expression; Replication of the SARS-CoV-1 genome; Replication of the SARS-CoV-2 genome; SUMOylation of transcription cofactors; mRNA Splicing - Major Pathway"	"6"	"6"	"4307.4"	"3363.0"	"4120.9"	"3756.6"	"3627.6"	"3623.5"	"4706.0"	"5655.9"	"5416.3"	"9243.6"	"13687.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P15924"	"Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3"	"0.000"	""	"8"	"23"	"46"	"23"	"2871"	"331.6"	"6.81"	"7757.46"	"78.60"	"22"	"22"	"cell adhesion;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00681, Pf17902, Pf18373"	"1832"	"ENSG00000096696"	"DSP"	"B2RTT2; D7RX09; hsa:1832; O75993; P15924; Q14189; Q9UHN4"	"Arrhythmogenic right ventricular cardiomyopathy; Lung fibrosis; Epithelial to mesenchymal transition in colorectal cancer"	"Neutrophil degranulation; Formation of the cornified envelope; RND3 GTPase cycle; RND1 GTPase cycle; Apoptotic cleavage of cell adhesion  proteins"	"9"	"0"	"2394.4"	"1977.2"	"2477.0"	"2213.7"	"2327.9"	"2132.2"	"2696.5"	"4146.2"	"4094.7"	"8234.7"	"11115.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12955"	"Ankyrin-3 OS=Homo sapiens OX=9606 GN=ANK3 PE=1 SV=3"	"0.000"	""	"6"	"23"	"42"	"21"	"4377"	"480.1"	"6.49"	"7970.03"	"77.95"	"21"	"21"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00531, Pf00791, Pf12796, Pf17809"	"288"	"ENSG00000151150"	"ANK3"	"B1AQT2; B4DIL1; E9PE32; hsa:288; Q12955; Q13484; Q5CZH9; Q5VXD5; Q7Z3G4; Q9H0P5"	"Splicing factor NOVA regulated synaptic proteins"	"COPI-mediated anterograde transport; Interaction between L1 and Ankyrins"	"3"	"2"	"2035.3"	"1613.3"	"1796.4"	"1775.7"	"1605.7"	"1647.6"	"2233.4"	"3536.1"	"3513.0"	"6208.7"	"7694.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12874"	"Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1"	"0.000"	""	"38"	"17"	"35"	"17"	"501"	"58.8"	"5.38"	"6615.67"	"77.87"	"13"	"15"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf11931, Pf12108, Pf13297, Pf16837"	"10946"	"ENSG00000183431"	"SF3A3"	"D3DPT5; hsa:10946; Q12874; Q15460; Q5VT87"	"Exercise-induced circadian regulation; mRNA processing"	"mRNA Splicing - Major Pathway"	"3"	"0"	"1281.8"	"1009.7"	"1105.8"	"1111.9"	"927.0"	"1061.7"	"1406.7"	"2797.6"	"2804.8"	"8174.4"	"12943.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96N67"	"Dedicator of cytokinesis protein 7 OS=Homo sapiens OX=9606 GN=DOCK7 PE=1 SV=4"	"0.000"	""	"13"	"23"	"42"	"23"	"2140"	"242.4"	"6.80"	"7275.12"	"77.77"	"19"	"21"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"other cell component"	"enzyme regulator activity;other molecular function"	"Pf06920, Pf11878, Pf14429, Pf20421, Pf20422"	"85440"	"ENSG00000116641"	"DOCK7"	"hsa:85440; Q00M63; Q2PPY7; Q45RE8; Q45RE9; Q5T1B9; Q5T1C0; Q6ZV32; Q8TB82; Q96N67; Q96NG6; Q96NI0; Q9C092"	""	"CDC42 GTPase cycle; RAC1 GTPase cycle; Factors involved in megakaryocyte development and platelet production; MET activates RAP1 and RAC1"	"4"	"0"	"1477.2"	"1132.5"	"1446.5"	"1391.5"	"1345.1"	"1551.8"	"2256.5"	"4514.1"	"4523.7"	"8945.2"	"10457.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BUQ8"	"Probable ATP-dependent RNA helicase DDX23 OS=Homo sapiens OX=9606 GN=DDX23 PE=1 SV=3"	"0.000"	""	"28"	"20"	"44"	"20"	"820"	"95.5"	"9.55"	"7648.73"	"77.69"	"17"	"19"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271"	"9416"	"ENSG00000174243"	"DDX23"	"B2R600; B4DH15; hsa:9416; O43188; Q9BUQ8"	""	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"2"	"0"	"1862.7"	"1536.9"	"1857.5"	"1676.9"	"1597.6"	"1614.1"	"2147.0"	"3292.9"	"3268.8"	"9276.0"	"15366.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P24928"	"DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2"	"0.000"	""	"14"	"22"	"43"	"22"	"1970"	"217.0"	"7.37"	"7846.06"	"77.51"	"20"	"21"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00623, Pf04983, Pf04990, Pf04992, Pf04997, Pf04998, Pf05000, Pf05001"	"5430"	""	"POLR2A"	"A6NN93; B9EH88; hsa:5430; P24928; Q6NX41"	"Pyrimidine metabolism; Eukaryotic transcription initiation; mRNA processing"	"Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; mRNA Splicing - Major Pathway; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"44"	"0"	"1654.2"	"1312.5"	"1712.3"	"1624.7"	"1512.1"	"1590.5"	"2077.3"	"2827.4"	"2711.8"	"5057.1"	"7087.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07910"	"Heterogeneous nuclear ribonucleoproteins C1/C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4"	"0.000"	""	"33"	"15"	"53"	"15"	"306"	"33.7"	"5.08"	"12149.46"	"77.46"	"15"	"13"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"3183"	"ENSG00000092199"	"HNRNPC"	"D3DS19; D3DS22; hsa:3183; P07910; P22628; Q53EX2; Q59FD3; Q5FWE8; Q86SF8; Q86U45; Q96HK7; Q96HM4; Q96IY5; Q9BTS3"	"mRNA processing"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA; SUMOylation of RNA binding proteins; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle"	"6"	"0"	"4426.7"	"4378.4"	"4349.6"	"3650.7"	"3828.2"	"3926.9"	"5040.7"	"5491.2"	"4983.8"	"8583.7"	"13361.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63010"	"AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1"	"0.000"	""	"20"	"17"	"43"	"10"	"937"	"104.5"	"5.38"	"7551.19"	"77.31"	"16"	"16"	"transport;developmental processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01602, Pf02883, Pf09066"	"163"	"ENSG00000006125"	"AP2B1"	"A6NJP3; hsa:163; P21851; P63010; Q7Z451; Q96J19"	"Synaptic vesicle pathway; GABA receptor signaling; EGF/EGFR signaling pathway; Fragile X syndrome; mBDNF and proBDNF regulation of GABA neurotransmission; Markers of kidney cell lineage; 17q12 copy number variation syndrome"	"Recycling pathway of L1; MHC class II antigen presentation; Cargo recognition for clathrin-mediated endocytosis; VLDLR internalisation and degradation; WNT5A-dependent internalization of FZD4; Retrograde neurotrophin signalling; Potential therapeutics for SARS; EPH-ephrin mediated repulsion of cells; LDL clearance; Nef Mediated CD4 Down-regulation; Nef Mediated CD8 Down-regulation; WNT5A-dependent internalization of FZD2, FZD5 and ROR2"	"20"	"7"	"1095.6"	"899.7"	"1186.0"	"1110.4"	"1100.7"	"2121.8"	"4336.1"	"9736.5"	"8502.0"	"9746.5"	"10420.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35580"	"Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3"	"0.000"	""	"12"	"19"	"36"	"15"	"1976"	"228.9"	"5.54"	"6963.94"	"76.39"	"16"	"18"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00063, Pf00612, Pf01576, Pf02736"	"4628"	"ENSG00000133026"	"MYH10"	"B2RWP9; D3DTS1; F8VTL3; hsa:4628; P35580; Q12989; Q149N3; Q149N4; Q16087; Q4LE45; Q6PK16; Q9BWG0"	"Regulation of actin cytoskeleton"	"EPHA-mediated growth cone collapse; RHO GTPases activate PAKs; RHO GTPases activate CIT; Sema4D induced cell migration and growth-cone collapse; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs"	"7"	"1"	"622.5"	"398.1"	"735.2"	"649.1"	"630.3"	"619.4"	"795.3"	"1680.4"	"1569.4"	"5818.2"	"9769.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99729"	"Heterogeneous nuclear ribonucleoprotein A/B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2"	"0.000"	""	"29"	"15"	"45"	"13"	"332"	"36.2"	"8.21"	"9110.37"	"76.38"	"14"	"12"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08143"	"3182"	"ENSG00000197451"	"HNRNPAB"	"B3KNN5; D3DWP7; hsa:3182; Q04150; Q8N7U3; Q99729; Q9BQ99"	"Pre-implantation embryo; mRNA processing"	""	"2"	"0"	"3315.0"	"2762.3"	"3273.1"	"2817.4"	"2916.7"	"2766.6"	"3695.4"	"4069.0"	"3717.4"	"5673.6"	"8659.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05455"	"Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2"	"0.000"	""	"41"	"23"	"48"	"23"	"408"	"46.8"	"7.12"	"10599.74"	"76.25"	"23"	"18"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf05383, Pf08777"	"6741"	"ENSG00000138385"	"SSB"	"hsa:6741; P05455; Q15367; Q53XJ4"	""	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Termination"	"2"	"0"	"3463.5"	"2628.8"	"3209.5"	"2935.4"	"2904.7"	"3255.0"	"4339.1"	"6627.1"	"5965.7"	"11832.4"	"15559.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43290"	"U4/U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1"	"0.000"	""	"27"	"16"	"36"	"16"	"800"	"90.2"	"6.13"	"7188.84"	"75.44"	"15"	"16"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	""	"Pf03343, Pf19252"	"9092"	"ENSG00000175467"	"SART1"	"A6NDN1; hsa:9092; O43290; Q53GB5"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"1561.8"	"1316.6"	"1451.0"	"1371.4"	"1407.5"	"1347.2"	"1784.7"	"2257.5"	"2074.3"	"3848.5"	"5341.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00571"	"ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3"	"0.000"	""	"34"	"25"	"48"	"25"	"662"	"73.2"	"7.18"	"9416.03"	"74.71"	"23"	"21"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;translation activity;nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"1654"	"ENSG00000215301"	"DDX3X"	"A8K538; B4E3E8; hsa:1654; O00571; O15536"	"Novel intracellular components of RIG-I-like receptor pathway; Hepatitis B infection"	"Neutrophil degranulation"	"3"	"0"	"3862.8"	"2987.2"	"3926.9"	"3569.9"	"3433.7"	"3379.3"	"4781.2"	"5805.0"	"5683.6"	"8948.1"	"10736.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BXP5"	"Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1"	"0.000"	""	"26"	"22"	"44"	"22"	"876"	"100.6"	"5.96"	"8930.64"	"74.53"	"21"	"19"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04959, Pf12066"	"51593"	"ENSG00000087087"	"SRRT"	"A4D2E5; A4D2E6; A6NK22; B4DJL4; B4DZA6; hsa:51593; O95808; Q32MI4; Q6NT74; Q8TDQ5; Q9BWP6; Q9BXP4; Q9BXP5; Q9Y4S4"	""	"mRNA Splicing - Major Pathway; RNA polymerase II transcribes snRNA genes"	"2"	"0"	"1726.9"	"1300.2"	"1885.8"	"1638.8"	"1640.2"	"1551.0"	"2113.6"	"3432.3"	"3211.2"	"11692.5"	"19222.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62316"	"Small nuclear ribonucleoprotein Sm D2 OS=Homo sapiens OX=9606 GN=SNRPD2 PE=1 SV=1"	"0.000"	""	"69"	"10"	"54"	"10"	"118"	"13.5"	"9.91"	"13400.40"	"74.47"	"9"	"9"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf01423"	"6633"	"ENSG00000125743"	"SNRPD2"	"A8K797; hsa:6633; J3KPM5; P43330; P62316"	"mRNA processing"	"mRNA Splicing - Major Pathway; SARS-CoV-2 modulates host translation machinery; snRNP Assembly; mRNA Splicing - Minor Pathway"	"5"	"0"	"2038.7"	"1269.3"	"2122.7"	"2062.8"	"1848.1"	"1729.6"	"2217.1"	"2506.4"	"2322.5"	"3723.7"	"5579.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKV3"	"Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2"	"0.000"	""	"19"	"22"	"46"	"22"	"1341"	"151.8"	"6.43"	"9403.62"	"74.34"	"19"	"17"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02037, Pf16294"	"22985"	"ENSG00000100813"	"ACIN1"	"B2RTT4; D3DS45; hsa:22985; O75158; Q9UG91; Q9UKV1; Q9UKV2; Q9UKV3"	""	"mRNA Splicing - Major Pathway; Apoptotic cleavage of cellular proteins"	"2"	"0"	"3953.7"	"3172.5"	"3717.2"	"3448.9"	"3263.7"	"3267.7"	"4264.3"	"5054.0"	"4752.7"	"9355.4"	"14691.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P40939"	"Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2"	"0.000"	""	"29"	"18"	"36"	"18"	"763"	"82.9"	"9.04"	"6240.61"	"73.78"	"15"	"18"	"other metabolic processes;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf00378, Pf00725, Pf02737"	"3030"	"ENSG00000084754"	"HADHA"	"B2R7L4; B4DYP2; hsa:3030; P40939; Q16679; Q53T69; Q53TA2; Q96GT7; Q9UQC5"	"Fatty acid beta-oxidation; Mitochondrial long chain fatty acid beta-oxidation; Valproic acid pathway; Mitochondrial fatty acid oxidation disorders; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Acyl chain remodeling of CL; mitochondrial fatty acid beta-oxidation of unsaturated fatty acids; Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA; Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of myristoyl-CoA to lauroyl-CoA; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA; Beta oxidation of palmitoyl-CoA to myristoyl-CoA"	"13"	"0"	"1140.8"	"844.0"	"1119.0"	"1042.7"	"923.7"	"1060.4"	"1387.1"	"2801.2"	"2846.2"	"8060.2"	"12148.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P78527"	"DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3"	"0.000"	""	"6"	"19"	"39"	"19"	"4128"	"468.8"	"7.12"	"8379.51"	"73.74"	"19"	"18"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00454, Pf02259, Pf02260, Pf08163, Pf19704, Pf20502"	"5591"	"ENSG00000253729"	"PRKDC"	"hsa:5591; P78527; P78528; Q13327; Q13337; Q14175; Q59H99; Q7Z611; Q96SE6; Q9UME3"	"miRNA regulation of DNA damage response; Cell cycle; Retinoblastoma gene in cancer; Fas ligand pathway and stress induction of heat shock proteins; Pathways affected in adenoid cystic carcinoma; ATM signaling in development and disease ; Non-homologous end joining; Osteoblast differentiation and related diseases; DNA repair pathways, full network; DNA damage response"	"E3 ubiquitin ligases ubiquitinate target proteins; Cytosolic sensors of pathogen-associated DNA ; Nonhomologous End-Joining (NHEJ); IRF3-mediated induction of type I IFN"	"14"	"0"	"1204.7"	"957.0"	"1185.4"	"1167.8"	"1118.6"	"1057.2"	"1401.0"	"2827.7"	"3050.5"	"6224.0"	"7779.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23284"	"Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2"	"0.000"	""	"50"	"15"	"41"	"15"	"216"	"23.7"	"9.41"	"7719.58"	"73.61"	"13"	"15"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00160"	"5479"	"ENSG00000166794"	"PPIB"	"A8K534; hsa:5479; P23284; Q6IBH5; Q9BVK5"	"Prolactin signaling pathway; Type I collagen synthesis in the context of osteogenesis imperfecta"	"Collagen biosynthesis and modifying enzymes; SARS-CoV-1 activates/modulates innate immune responses"	"4"	"0"	"1403.4"	"1152.5"	"1588.3"	"1564.2"	"1875.6"	"2737.4"	"4075.9"	"8672.2"	"8405.4"	"10551.5"	"7902.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UHB6"	"LIM domain and actin-binding protein 1 OS=Homo sapiens OX=9606 GN=LIMA1 PE=1 SV=1"	"0.000"	""	"28"	"18"	"36"	"18"	"759"	"85.2"	"6.84"	"5883.09"	"73.59"	"13"	"18"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412"	"51474"	"ENSG00000050405"	"LIMA1"	"B2RB09; hsa:51474; Q2TAN7; Q59FE8; Q9BVF2; Q9H8J1; Q9HBN5; Q9NX96; Q9NXC3; Q9NXU6; Q9P0H8; Q9UHB5; Q9UHB6"	""	""	"0"	"0"	"1772.9"	"1518.1"	"1577.2"	"1585.0"	"1612.9"	"1611.5"	"1946.6"	"3111.9"	"3078.3"	"7221.5"	"8012.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P54136"	"Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2"	"0.000"	""	"29"	"16"	"36"	"16"	"660"	"75.3"	"6.68"	"7581.51"	"73.42"	"16"	"16"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00750, Pf03485, Pf05746"	"5917"	"ENSG00000113643"	"RARS1"	"B2RBS9; hsa:5917; P54136; Q53GY4; Q9BWA1"	"Amino acid metabolism"	"Cytosolic tRNA aminoacylation; Selenoamino acid metabolism"	"3"	"0"	"431.8"	"323.3"	"456.6"	"442.8"	"404.6"	"424.5"	"560.4"	"2120.1"	"2225.0"	"7432.6"	"10918.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35611"	"Alpha-adducin OS=Homo sapiens OX=9606 GN=ADD1 PE=1 SV=2"	"0.000"	""	"25"	"16"	"33"	"14"	"737"	"80.9"	"5.83"	"5732.84"	"73.25"	"13"	"16"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00596"	"118"	"ENSG00000087274"	"ADD1"	"A2A3N8; A2A3P0; B4DI79; D3DVR3; D3DVR4; D3DVR5; hsa:118; P35611; Q13734; Q14729; Q16156; Q86XM2; Q9UJB6"	""	"XBP1(S) activates chaperone genes; Caspase-mediated cleavage of cytoskeletal proteins; Miscellaneous transport and binding events"	"3"	"2"	"1313.0"	"960.2"	"1096.3"	"1100.4"	"1007.0"	"1045.5"	"1327.1"	"3374.0"	"3258.0"	"5963.7"	"6558.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P15311"	"Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4"	"0.000"	""	"36"	"24"	"47"	"14"	"586"	"69.4"	"6.27"	"8888.96"	"72.82"	"23"	"19"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf00769, Pf09379, Pf09380, Pf20492"	"7430"	"ENSG00000092820"	"EZR"	"E1P5A8; hsa:7430; P15311; P23714; Q4VX75; Q96CU8; Q9NSJ4"	"Pathogenic Escherichia coli infection; AGE/RAGE pathway; VEGFA-VEGFR2 signaling; 16p11.2 proximal deletion syndrome; CCL18 signaling pathway; Regulation of actin cytoskeleton; GDNF signaling"	"Recycling pathway of L1; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Netrin-1 signaling"	"11"	"10"	"2758.8"	"2033.6"	"2782.9"	"2392.5"	"2577.7"	"2732.8"	"3437.8"	"7329.1"	"7467.3"	"10737.0"	"9311.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52597"	"Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3"	"0.000"	""	"26"	"13"	"36"	"10"	"415"	"45.6"	"5.58"	"4839.57"	"72.40"	"10"	"12"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf08080"	"3185"	"ENSG00000169813"	"HNRNPF"	"B3KM84; hsa:3185; P52597; Q5T0N2; Q96AU2"	"MECP2 and associated Rett syndrome"	"mRNA Splicing - Major Pathway; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	"5"	"0"	"1948.0"	"1533.6"	"1410.1"	"1400.4"	"1300.0"	"1422.5"	"2046.1"	"3180.0"	"2954.1"	"5215.3"	"6492.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92945"	"Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4"	"0.000"	""	"31"	"16"	"34"	"14"	"711"	"73.1"	"7.30"	"6332.85"	"72.11"	"14"	"14"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf09005"	"8570"	"ENSG00000088247"	"KHSRP"	"hsa:8570; O00301; Q59EZ9; Q5U4P6; Q92945; Q9UNT5; Q9UQH5"	"Pre-implantation embryo"	"ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA"	"3"	"2"	"1657.7"	"1452.8"	"1626.0"	"1518.2"	"1556.8"	"1569.0"	"1950.5"	"2712.1"	"2617.9"	"4745.1"	"6524.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35527"	"Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3"	"0.000"	""	"29"	"18"	"39"	"16"	"623"	"62.0"	"5.24"	"7427.34"	"71.94"	"15"	"15"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton"	"cytoskeletal activity"	"Pf00038"	"3857"	"ENSG00000171403"	"KRT9"	"hsa:3857; O00109; P35527; Q0IJ47; Q14665"	""	"Formation of the cornified envelope"	"2"	"2"	"611.7"	"1426.9"	"8159.7"	"1672.0"	"2354.6"	"999.1"	"836.5"	"4319.5"	"5087.1"	"7014.5"	"8418.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q06830"	"Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1"	"0.000"	""	"60"	"16"	"37"	"15"	"199"	"22.1"	"8.13"	"7636.39"	"71.93"	"14"	"14"	"cell cycle OR cell proliferation;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00578, Pf10417"	"5052"	"ENSG00000117450"	"PRDX1"	"B5BU26; D3DPZ8; hsa:5052; P35703; Q06830; Q2V576; Q5T154; Q5T155"	"Androgen receptor signaling pathway; Selenium micronutrient network; Nuclear receptors meta-pathway; NRF2 pathway"	"Detoxification of Reactive Oxygen Species; TP53 Regulates Metabolic Genes; NFE2L2 regulating anti-oxidant/detoxification enzymes; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"	"8"	"1"	"1657.9"	"1263.6"	"1769.9"	"1517.7"	"1502.4"	"1352.9"	"1851.5"	"3771.6"	"3349.1"	"9406.6"	"14659.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15233"	"Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4"	"0.000"	""	"29"	"16"	"43"	"14"	"471"	"54.2"	"8.95"	"8947.88"	"71.81"	"15"	"15"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08075"	"4841"	"ENSG00000147140"	"NONO"	"B7Z4C2; D3DVV4; F5GYZ3; hsa:4841; O00201; P30807; Q12786; Q15233; Q9BQC5"	"mRNA processing"	""	"1"	"1"	"2958.8"	"2337.0"	"3006.3"	"2844.1"	"2741.3"	"2734.9"	"3509.5"	"4266.8"	"4042.2"	"6358.6"	"8928.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55265"	"Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4"	"0.000"	""	"16"	"15"	"34"	"15"	"1226"	"136.0"	"8.65"	"7163.96"	"71.42"	"13"	"13"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00035, Pf02137, Pf02295"	"103"	"ENSG00000160710"	"ADAR"	"B1AQQ9; B1AQR0; D3DV76; hsa:103; O15223; O43859; O43860; P55265; Q9BYM3; Q9BYM4"	"Measles virus infection; Cytosolic DNA-sensing pathway"	"Interferon alpha/beta signaling; C6 deamination of adenosine; Formation of editosomes by ADAR proteins"	"5"	"0"	"1940.0"	"1422.2"	"1895.8"	"1820.4"	"1720.7"	"1635.9"	"2272.2"	"3163.3"	"2862.5"	"5709.2"	"8226.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14204"	"Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5"	"0.000"	""	"6"	"20"	"35"	"20"	"4646"	"532.1"	"6.40"	"6004.40"	"71.16"	"15"	"19"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03028, Pf08385, Pf08393, Pf12774, Pf12775, Pf12777, Pf12780, Pf12781, Pf17852, Pf18198, Pf18199"	"1778"	"ENSG00000197102"	"DYNC1H1"	"B0I1R0; hsa:1778; Q14204; Q6DKQ7; Q8WU28; Q92814; Q9Y4G5"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein; PAFAH1B1 copy number variation"	"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Neutrophil degranulation; HCMV Early Events; Separation of Sister Chromatids; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; Recruitment of NuMA to mitotic centrosomes; RHO GTPases Activate Formins; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Aggrephagy; EML4 and NUDC in mitotic spindle formation; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"23"	"0"	"660.5"	"510.3"	"669.2"	"607.2"	"628.3"	"655.8"	"772.0"	"1586.5"	"1660.1"	"4889.9"	"6778.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25205"	"DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3"	"0.000"	""	"28"	"18"	"33"	"18"	"808"	"90.9"	"5.77"	"5823.91"	"70.89"	"14"	"15"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf14551, Pf17207, Pf17855"	"4172"	"ENSG00000112118"	"MCM3"	"B4DWW4; hsa:4172; P25205; Q92660; Q9BTR3; Q9NUE7"	"Cell cycle; Retinoblastoma gene in cancer; Ciliary landscape; G1 to S cell cycle control; DNA replication"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"11"	"0"	"2148.4"	"1830.7"	"2016.6"	"1794.7"	"1834.8"	"1925.9"	"2552.6"	"3518.2"	"3119.7"	"6911.3"	"10770.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52948"	"Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4"	"0.000"	""	"11"	"19"	"39"	"19"	"1817"	"197.5"	"6.40"	"6511.10"	"70.60"	"16"	"18"	"cell organization and biogenesis;protein metabolism;transport;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04096, Pf12110"	"4928"	"ENSG00000110713"	"NUP98"	"hsa:4928; P52948; Q8IUT2; Q8WYB0; Q96E54; Q9H3Q4; Q9NT02; Q9UF57; Q9UHX0; Q9Y6J4; Q9Y6J5"	"SARS-CoV-2 innate immunity evasion and cell-specific immune response"	""	"1"	"0"	"1807.4"	"1382.1"	"1658.1"	"1528.2"	"1529.0"	"1608.1"	"2072.3"	"2811.3"	"2792.5"	"5037.4"	"6941.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43776"	"Asparagine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=NARS1 PE=1 SV=1"	"0.000"	""	"35"	"17"	"37"	"17"	"548"	"62.9"	"6.25"	"8804.23"	"69.80"	"14"	"13"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00152, Pf01336"	"4677"	"ENSG00000134440"	"NARS1"	"B4DG16; hsa:4677; O43776; Q53GU6"	"Photodynamic therapy-induced unfolded protein response"	"Cytosolic tRNA aminoacylation"	"2"	"0"	"2489.0"	"2008.4"	"2275.4"	"2194.5"	"2083.0"	"2045.6"	"2855.7"	"6895.5"	"6564.9"	"12333.6"	"11885.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30101"	"Protein disulfide-isomerase A3 OS=Homo sapiens OX=9606 GN=PDIA3 PE=1 SV=4"	"0.000"	""	"43"	"18"	"32"	"18"	"505"	"56.7"	"6.35"	"5225.92"	"69.48"	"12"	"16"	"cell adhesion;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"non-structural extracellular;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00085, Pf13848"	"2923"	"ENSG00000167004"	"PDIA3"	"hsa:2923; P30101; Q13453; Q14255; Q8IYF8; Q9UMU7"	"Prion disease pathway"	"ER-Phagosome pathway; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Calnexin/calreticulin cycle"	"4"	"0"	"480.8"	"374.5"	"585.0"	"503.2"	"513.1"	"576.9"	"726.4"	"1378.9"	"1297.1"	"7332.2"	"17229.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P06748"	"Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2"	"0.000"	""	"46"	"17"	"49"	"17"	"294"	"32.6"	"4.78"	"11946.57"	"69.43"	"16"	"13"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;translation activity;nucleic acid binding activity;other molecular function"	"Pf03066, Pf16276"	"4869"	"ENSG00000181163"	"NPM1"	"A8K3N7; B5BU00; D3DQL6; hsa:4869; P06748; P08693; Q12826; Q13440; Q13441; Q14115; Q5EU94; Q5EU95; Q5EU96; Q5EU97; Q5EU98; Q5EU99; Q6V962; Q8WTW5; Q96AT6; Q96DC4; Q96EA5; Q9BYG9; Q9UDJ7"	""	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain; Nuclear import of Rev protein; Deposition of new CENPA-containing nucleosomes at the centromere; SUMOylation of transcription cofactors; ALK mutants bind TKIs; Nuclear events stimulated by ALK signaling in cancer; TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation; SARS-CoV-1-host interactions"	"9"	"0"	"7987.0"	"6484.9"	"6541.4"	"6154.4"	"5930.2"	"6119.5"	"7930.4"	"10737.2"	"9244.8"	"13600.7"	"15916.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TAF3"	"WD repeat-containing protein 48 OS=Homo sapiens OX=9606 GN=WDR48 PE=1 SV=1"	"0.000"	""	"29"	"14"	"31"	"14"	"677"	"76.2"	"7.03"	"5266.98"	"69.26"	"11"	"13"	"DNA metabolism;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00400, Pf11816"	"57599"	"ENSG00000114742"	"WDR48"	"B4DM86; B4DQI2; B4DY84; hsa:57599; Q63HJ2; Q658Y1; Q8N3Z1; Q8TAF3; Q9NSK8; Q9P279"	"DNA repair pathways, full network"	"Ub-specific processing proteases; Fanconi Anemia Pathway; Signaling by cytosolic PDGFRA and PDGFRB fusion proteins; Recognition of DNA damage by PCNA-containing replication complex"	"5"	"0"	"522.2"	"397.8"	"556.1"	"540.1"	"502.5"	"569.5"	"845.5"	"2819.6"	"2869.0"	"6978.5"	"7159.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P57740"	"Nuclear pore complex protein Nup107 OS=Homo sapiens OX=9606 GN=NUP107 PE=1 SV=1"	"0.000"	""	"13"	"12"	"29"	"12"	"925"	"106.3"	"5.43"	"5922.19"	"69.25"	"10"	"11"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes"	"other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf04121"	"57122"	"ENSG00000111581"	"NUP107"	"B4DZ67; hsa:57122; P57740; Q6PJE1"	"Gastric cancer network 1; Primary ovarian insufficiency"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; SUMOylation of DNA damage response and repair proteins; Vpr-mediated nuclear import of PICs; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Regulation of HSF1-mediated heat shock response; SUMOylation of chromatin organization proteins; HCMV Late Events; HCMV Early Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; snRNP Assembly; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; SUMOylation of SUMOylation proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; Postmitotic nuclear pore complex (NPC) reformation"	"37"	"0"	"1131.8"	"880.3"	"986.8"	"1054.5"	"908.2"	"931.9"	"1247.1"	"1741.5"	"1798.0"	"2758.4"	"3751.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95602"	"DNA-directed RNA polymerase I subunit RPA1 OS=Homo sapiens OX=9606 GN=POLR1A PE=1 SV=2"	"0.000"	""	"14"	"18"	"36"	"18"	"1720"	"194.7"	"7.03"	"7375.95"	"68.89"	"15"	"16"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00623, Pf04983, Pf04997, Pf04998, Pf05000"	"25885"	"ENSG00000068654"	"POLR1A"	"B7Z7T0; D6W5M0; hsa:25885; O95602; Q0VG05; Q9UEH0; Q9UFT9"	"Pyrimidine metabolism; Eukaryotic transcription initiation; 2q13 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"8"	"0"	"562.3"	"444.0"	"588.4"	"569.4"	"521.7"	"570.5"	"799.3"	"3477.1"	"3927.5"	"10030.6"	"13065.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P43243"	"Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2"	"0.000"	""	"23"	"23"	"39"	"23"	"847"	"94.6"	"6.25"	"7613.81"	"68.78"	"20"	"19"	"stress response;developmental processes;other biological processes"	"other membranes;nucleus"	"nucleic acid binding activity;other molecular function"	""	"9782"	"ENSG00000015479"	"MATR3"	"B7ZAV5; D3DQC3; hsa:9782; P43243; Q9UHW0; Q9UQ27"	""	""	"0"	"0"	"2990.1"	"2366.3"	"2793.0"	"2624.7"	"2427.7"	"2467.1"	"3500.3"	"4601.4"	"4169.8"	"8076.6"	"11988.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2W1"	"Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2"	"0.000"	""	"21"	"19"	"42"	"19"	"955"	"108.6"	"10.15"	"8822.40"	"68.67"	"19"	"16"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf15440"	"9967"	"ENSG00000054118"	"THRAP3"	"D3DPS5; hsa:9967; Q5VTK6; Q9Y2W1"	"Interactome of polycomb repressive complex 2 (PRC2)"	"PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation"	"3"	"0"	"2852.5"	"2348.3"	"2431.2"	"2417.2"	"2266.0"	"2258.8"	"2916.7"	"3936.5"	"3643.4"	"8068.6"	"13338.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14678"	"Small nuclear ribonucleoprotein-associated proteins B and B' OS=Homo sapiens OX=9606 GN=SNRPB PE=1 SV=2"	"0.000"	""	"22"	"7"	"30"	"7"	"240"	"24.6"	"11.19"	"3719.49"	"67.81"	"5"	"7"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01423"	"6628"	"ENSG00000125835"	"SNRPB"	"hsa:6628; P14678; Q15490; Q6IB35; Q9UIS5"	"mRNA processing"	"snRNP Assembly; RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway; SARS-CoV-2 modulates host translation machinery; mRNA Splicing - Minor Pathway; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"8"	"0"	"1193.0"	"707.1"	"1235.6"	"1075.4"	"893.6"	"932.1"	"1333.3"	"2116.9"	"1843.5"	"4322.8"	"6775.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P26368"	"Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4"	"0.000"	""	"31"	"11"	"34"	"11"	"475"	"53.5"	"9.09"	"6193.44"	"67.46"	"9"	"10"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"11338"	"ENSG00000063244"	"U2AF2"	"hsa:11338; P26368; Q96HC5"	"mRNA processing; Warburg effect modulated by deubiquitinating enzymes and their substrates"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway"	"6"	"0"	"590.7"	"465.8"	"670.4"	"598.2"	"563.0"	"553.0"	"865.4"	"3912.1"	"4783.0"	"16359.1"	"20614.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2J2"	"Band 4.1-like protein 3 OS=Homo sapiens OX=9606 GN=EPB41L3 PE=1 SV=2"	"0.000"	""	"17"	"17"	"34"	"13"	"1087"	"120.6"	"5.19"	"6200.18"	"67.33"	"14"	"15"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf04382, Pf05902, Pf08736, Pf09379, Pf09380"	"23136"	"ENSG00000082397"	"EPB41L3"	"B7Z4I5; F5GX05; hsa:23136; O95713; Q9BRP5; Q9Y2J2"	"Splicing factor NOVA regulated synaptic proteins"	"Neurexins and neuroligins; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea"	"4"	"0"	"1398.1"	"1096.8"	"1267.9"	"1250.9"	"1180.2"	"1236.9"	"1598.4"	"3225.8"	"3100.3"	"3154.8"	"3664.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92917"	"G-patch domain and KOW motifs-containing protein OS=Homo sapiens OX=9606 GN=GPKOW PE=1 SV=2"	"0.000"	""	"33"	"12"	"28"	"12"	"476"	"52.2"	"6.15"	"5609.09"	"67.25"	"8"	"12"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00467, Pf12656"	"27238"	"ENSG00000068394"	"GPKOW"	"hsa:27238; Q59EK5; Q92917; Q9BQA8"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"509.5"	"451.0"	"587.7"	"560.1"	"549.6"	"599.7"	"778.6"	"2262.6"	"2343.5"	"5381.7"	"7120.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13645"	"Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6"	"0.000"	""	"28"	"16"	"34"	"13"	"584"	"58.8"	"5.21"	"6924.65"	"67.23"	"14"	"15"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;cytosol;cytoskeleton;other cell component"	"bone, tooth or skin structural activity;other molecular function"	"Pf00038"	"3858"	"ENSG00000186395"	"KRT10"	"hsa:3858; P13645; Q14664; Q8N175"	""	"Formation of the cornified envelope"	"2"	"2"	"674.0"	"887.4"	"3521.5"	"1364.2"	"1818.9"	"873.6"	"1246.5"	"3947.4"	"6558.6"	"6239.0"	"5685.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UMS4"	"Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1"	"0.000"	""	"34"	"14"	"35"	"14"	"504"	"55.1"	"6.61"	"5641.57"	"67.18"	"12"	"13"	"cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00400, Pf04564, Pf08606"	"27339"	"ENSG00000110107"	"PRPF19"	"hsa:27339; Q9UMS4"	""	"mRNA Splicing - Major Pathway; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of TC-NER Pre-Incision Complex"	"5"	"0"	"686.2"	"489.3"	"731.2"	"653.6"	"572.7"	"678.8"	"1005.4"	"3936.1"	"4192.1"	"15200.3"	"19069.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q00688"	"Peptidyl-prolyl cis-trans isomerase FKBP3 OS=Homo sapiens OX=9606 GN=FKBP3 PE=1 SV=1"	"0.000"	""	"42"	"16"	"40"	"16"	"224"	"25.2"	"9.28"	"8345.53"	"66.88"	"15"	"13"	""	"nucleus"	"other molecular function"	"Pf00254, Pf18410"	"2287"	"ENSG00000100442"	"FKBP3"	"B2R4Q9; hsa:2287; Q00688; Q14317"	""	""	"0"	"0"	"2354.1"	"1933.8"	"2199.3"	"2004.5"	"1997.8"	"2056.7"	"2769.5"	"5823.8"	"5298.2"	"10285.0"	"12889.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13573"	"SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1"	"0.000"	""	"28"	"14"	"34"	"14"	"536"	"61.5"	"9.52"	"7122.63"	"66.56"	"13"	"13"	"RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus"	"signal transduction activity or receptor binding;other molecular function"	"Pf02731"	"22938"	"ENSG00000100603"	"SNW1"	"A8K8A9; hsa:22938; Q13483; Q13573; Q32N03; Q5D0D6"	"Novel intracellular components of RIG-I-like receptor pathway; Splicing factor NOVA regulated synaptic proteins; Notch signaling pathway"	"mRNA Splicing - Major Pathway; Formation of paraxial mesoderm; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Pre-NOTCH Transcription and Translation; Downregulation of SMAD2/3:SMAD4 transcriptional activity; NOTCH1 Intracellular Domain Regulates Transcription; Notch-HLH transcription pathway; NOTCH3 Intracellular Domain Regulates Transcription; Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells; NOTCH4 Intracellular Domain Regulates Transcription; RUNX3 regulates NOTCH signaling"	"15"	"0"	"2376.9"	"2356.9"	"2074.6"	"2120.1"	"2013.3"	"2050.8"	"2703.0"	"3489.9"	"3250.8"	"6136.9"	"10265.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92878"	"DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1"	"0.000"	""	"15"	"16"	"32"	"16"	"1312"	"153.8"	"6.89"	"4808.37"	"65.85"	"13"	"16"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04423, Pf13476, Pf13558"	"10111"	"ENSG00000113522"	"RAD50"	"B9EGF5; hsa:10111; O43254; Q6GMT7; Q6P5X3; Q92878; Q9UP86"	"miRNA regulation of DNA damage response; Homologous recombination; DDX1 as a regulatory component of the Drosha microprocessor; ATM signaling in development and disease ; Breast cancer pathway; Joubert syndrome; DNA repair pathways, full network; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; DNA damage response"	"Sensing of DNA Double Strand Breaks; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Resolution of D-loop Structures through Holliday Junction Intermediates; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; Meiotic recombination; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; DNA Damage/Telomere Stress Induced Senescence; Nonhomologous End-Joining (NHEJ); HDR through MMEJ (alt-NHEJ)"	"29"	"0"	"922.7"	"677.6"	"896.5"	"853.3"	"789.2"	"801.1"	"1114.6"	"2099.6"	"2145.1"	"5745.0"	"9271.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WUM0"	"Nuclear pore complex protein Nup133 OS=Homo sapiens OX=9606 GN=NUP133 PE=1 SV=2"	"0.000"	""	"20"	"19"	"40"	"19"	"1156"	"128.9"	"5.10"	"8769.09"	"65.47"	"18"	"15"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf03177"	"55746"	"ENSG00000069248"	"NUP133"	"B2RAZ8; hsa:55746; Q5T8N0; Q8WUM0; Q9H9W2; Q9NV71; Q9NVC4"	"Ciliary landscape"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; SUMOylation of DNA replication proteins; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Transport of Mature mRNA derived from an Intron-Containing Transcript; snRNP Assembly; SARS-CoV-2 activates/modulates innate and adaptive immune responses; HCMV Early Events; SUMOylation of DNA damage response and repair proteins; Regulation of HSF1-mediated heat shock response; HCMV Late Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; Postmitotic nuclear pore complex (NPC) reformation"	"36"	"0"	"2049.9"	"1336.2"	"1997.8"	"1970.6"	"1687.0"	"1824.8"	"2414.8"	"3738.2"	"3809.5"	"7125.9"	"9514.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43719"	"HIV Tat-specific factor 1 OS=Homo sapiens OX=9606 GN=HTATSF1 PE=1 SV=1"	"0.000"	""	"21"	"13"	"28"	"13"	"755"	"85.8"	"4.40"	"5385.29"	"65.14"	"10"	"11"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	"Pf00076"	"27336"	"ENSG00000102241"	"HTATSF1"	"D3DWG9; hsa:27336; O43719; Q59G06; Q99730"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"1328.8"	"1004.8"	"1316.4"	"1267.8"	"1201.8"	"1186.3"	"1503.3"	"2317.8"	"2277.4"	"5453.5"	"8838.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07900"	"Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5"	"0.000"	""	"27"	"19"	"35"	"6"	"732"	"84.6"	"5.02"	"5801.21"	"65.04"	"14"	"17"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"non-structural extracellular;extracellular matrix;plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00183, Pf02518"	"3320"	"ENSG00000080824"	"HSP90AA1"	"A8K500; B3KPJ9; hsa:3320; P07900; Q2PP14; Q5CAQ6; Q5CAQ7; Q9BVQ5"	"Nucleotide-binding oligomerization domain (NOD) pathway; TNF-alpha signaling pathway; Corticotropin-releasing hormone signaling pathway; Aryl hydrocarbon receptor pathway; Ebstein-Barr virus LMP1 signaling; Aryl hydrocarbon receptor pathway; Constitutive androstane receptor pathway; Pregnane X receptor pathway; Glucocorticoid receptor pathway; Nuclear receptors meta-pathway; NRF2 pathway; VEGFA-VEGFR2 signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Th17 cell differentiation pathway"	"Neutrophil degranulation; Estrogen-dependent gene expression; Regulation of actin dynamics for phagocytic cup formation; Potential therapeutics for SARS; The role of GTSE1 in G2/M progression after G2 checkpoint; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Recruitment of NuMA to mitotic centrosomes; Aggrephagy; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Extra-nuclear estrogen signaling; vRNP Assembly; Regulation of necroptotic cell death; Interleukin-4 and Interleukin-13 signaling; Downregulation of ERBB2 signaling; Signaling by ERBB2 KD Mutants; Signaling by ERBB2 TMD/JMD mutants; Sema3A PAK dependent Axon repulsion; DDX58/IFIH1-mediated induction of interferon-alpha/beta; PIWI-interacting RNA (piRNA) biogenesis; VEGFR2 mediated vascular permeability; RHOBTB2 GTPase cycle; Chaperone Mediated Autophagy; HSF1 activation; Attenuation phase; eNOS activation; Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation; Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; Constitutive Signaling by EGFRvIII; Signaling by ERBB2 ECD mutants; Uptake and function of diphtheria toxin; Constitutive Signaling by Overexpressed ERBB2; Scavenging by Class F Receptors; Drug-mediated inhibition of ERBB2 signaling; Resistance of ERBB2 KD mutants to trastuzumab; Resistance of ERBB2 KD mutants to sapitinib; Resistance of ERBB2 KD mutants to tesevatinib; Resistance of ERBB2 KD mutants to neratinib; Resistance of ERBB2 KD mutants to osimertinib; Resistance of ERBB2 KD mutants to afatinib; Resistance of ERBB2 KD mutants to AEE788; Resistance of ERBB2 KD mutants to lapatinib; Drug resistance in ERBB2 TMD/JMD mutants"	"67"	"0"	"480.2"	"343.5"	"471.3"	"453.7"	"383.7"	"367.3"	"516.2"	"730.9"	"626.9"	"1170.9"	"1889.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q1KMD3"	"Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1"	"0.000"	""	"28"	"18"	"35"	"18"	"747"	"85.1"	"4.91"	"6223.35"	"64.67"	"16"	"15"	""	"nucleus;other cell component"	""	"Pf00622, Pf02037, Pf13671"	"221092"	"ENSG00000214753"	"HNRNPUL2"	"hsa:221092; Q1KMD3; Q8N3B3"	""	""	"0"	"0"	"1870.0"	"1437.2"	"1889.1"	"1618.9"	"1594.3"	"1673.2"	"2262.7"	"3921.5"	"3373.4"	"7375.8"	"10873.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P12081"	"Histidine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=HARS1 PE=1 SV=2"	"0.000"	""	"42"	"20"	"35"	"15"	"509"	"57.4"	"5.88"	"5962.86"	"63.89"	"14"	"18"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00458, Pf03129, Pf13393"	"3035"	"ENSG00000170445"	"HARS1"	"B4DHQ1; B4DY73; D6REN6; hsa:3035; J3KNE5; P12081"	"Allograft rejection"	"Cytosolic tRNA aminoacylation"	"2"	"5"	"628.8"	"519.5"	"620.9"	"602.9"	"595.7"	"751.1"	"892.5"	"2673.6"	"2779.7"	"8609.0"	"14462.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NTJ3"	"Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2"	"0.000"	""	"18"	"20"	"36"	"20"	"1288"	"147.1"	"6.79"	"6522.76"	"63.28"	"17"	"17"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02463, Pf06470"	"10051"	"ENSG00000113810"	"SMC4"	"A6NLT9; D3DNL8; hsa:10051; O95752; Q8NDL4; Q9NTJ3; Q9UNT9"	"Ciliary landscape"	"Condensation of Prophase Chromosomes; Condensation of Prometaphase Chromosomes"	"3"	"0"	"2020.7"	"1660.8"	"2058.7"	"1853.7"	"1910.9"	"1957.3"	"2484.5"	"3626.7"	"3465.8"	"6275.0"	"8078.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H307"	"Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5"	"0.000"	""	"27"	"14"	"30"	"14"	"717"	"81.6"	"7.14"	"5598.45"	"63.00"	"11"	"13"	"cell adhesion;RNA metabolism OR transcription;other metabolic processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04696, Pf04697"	"5411"	"ENSG00000100941"	"PNN"	"B4DZX8; hsa:5411; O60899; Q53EM7; Q6P5X4; Q7KYL1; Q99738; Q9H307; Q9UHZ9; Q9UQR9"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"1607.4"	"1167.6"	"1521.4"	"1471.5"	"1307.7"	"1410.7"	"1820.1"	"2120.3"	"2060.7"	"3594.7"	"5808.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11940"	"Polyadenylate-binding protein 1 OS=Homo sapiens OX=9606 GN=PABPC1 PE=1 SV=2"	"0.000"	""	"28"	"16"	"37"	"12"	"636"	"70.6"	"9.50"	"6797.79"	"62.77"	"15"	"16"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf00658"	"26986"	"ENSG00000070756"	"PABPC1"	"hsa:26986; P11940; Q15097; Q93004"	"Translation factors; Endoderm differentiation; VEGFA-VEGFR2 signaling; Acute viral myocarditis"	"AUF1 (hnRNP D0) binds and destabilizes mRNA; Regulation of expression of SLITs and ROBOs; Deadenylation of mRNA; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"11"	"3"	"2523.7"	"2100.2"	"2438.0"	"2248.1"	"2148.8"	"2229.6"	"2916.8"	"3492.8"	"3168.4"	"5622.3"	"7995.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35221"	"Catenin alpha-1 OS=Homo sapiens OX=9606 GN=CTNNA1 PE=1 SV=1"	"0.000"	""	"21"	"16"	"30"	"16"	"906"	"100.0"	"6.29"	"5172.23"	"61.83"	"14"	"15"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01044"	"1495"	"ENSG00000044115"	"CTNNA1"	"hsa:1495; P35221; Q12795; Q8N1C0"	"Arrhythmogenic right ventricular cardiomyopathy; Apoptosis-related network due to altered Notch3 in ovarian cancer; VEGFA-VEGFR2 signaling; White fat cell differentiation; Endometrial cancer; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-Merlin signaling dysregulation; Pleural mesothelioma"	"RHO GTPases activate IQGAPs; Myogenesis; Adherens junctions interactions; VEGFR2 mediated vascular permeability; Regulation of CDH11 function; Regulation of CDH19 Expression and Function; CDH11 homotypic and heterotypic interactions"	"15"	"0"	"362.1"	"259.6"	"467.7"	"406.5"	"400.6"	"410.5"	"494.0"	"1864.3"	"1935.6"	"5861.4"	"6742.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P27695"	"DNA-(apurinic or apyrimidinic site) lyase OS=Homo sapiens OX=9606 GN=APEX1 PE=1 SV=2"	"0.000"	""	"53"	"13"	"30"	"13"	"318"	"35.5"	"8.12"	"6451.64"	"61.69"	"11"	"11"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;mitochondrion;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03372"	"328"	"ENSG00000100823"	"APEX1"	"hsa:328; P27695; Q969L5; Q99775"	"Thyroid stimulating hormone (TSH) signaling pathway; Spinal cord injury; Base excision repair; DNA repair pathways, full network"	"Displacement of DNA glycosylase by APEX1; POLB-Dependent Long Patch Base Excision Repair; PCNA-Dependent Long Patch Base Excision Repair; Abasic sugar-phosphate removal via the single-nucleotide replacement pathway"	"10"	"0"	"994.6"	"915.6"	"896.3"	"906.4"	"867.2"	"876.7"	"1217.0"	"3934.2"	"3772.7"	"7079.6"	"6797.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P68104"	"Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1"	"0.000"	""	"42"	"17"	"36"	"9"	"462"	"50.1"	"9.01"	"5821.55"	"61.60"	"13"	"13"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;translational apparatus;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03143, Pf03144"	"1915"	"ENSG00000156508"	"EEF1A1"	"hsa:1915; P04719; P04720; P68104; Q6IQ15"	"Translation factors; Fragile X syndrome; 2q37 copy number variation syndrome"	"Neutrophil degranulation; Chaperone Mediated Autophagy; Protein methylation; Peptide chain elongation; HSF1 activation; SARS-CoV-1 modulates host translation machinery"	"10"	"9"	"3134.1"	"3226.4"	"2392.0"	"2352.8"	"2262.6"	"2521.7"	"3199.3"	"5660.9"	"5441.5"	"11374.1"	"15761.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43852"	"Calumenin OS=Homo sapiens OX=9606 GN=CALU PE=1 SV=2"	"0.000"	""	"51"	"14"	"31"	"14"	"315"	"37.1"	"4.64"	"6352.85"	"61.60"	"13"	"12"	""	"non-structural extracellular;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf13833"	"813"	"ENSG00000128595"	"CALU"	"B3KPG9; D6QS48; D6QS49; D6QS50; D6QS51; D6QS52; D6QS53; D6QS54; D6QS55; D6QS56; D6QS57; D6QS58; D6QS59; F5H1Q9; F5H879; hsa:813; O43852; O60456; Q6FHB9; Q96RL3; Q9NR43"	"NOTCH1 regulation of endothelial cell calcification; VEGFA-VEGFR2 signaling"	"Platelet degranulation ; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation"	"5"	"0"	"2422.3"	"1948.1"	"2272.9"	"2392.9"	"2251.0"	"2224.1"	"2801.0"	"2923.8"	"2881.8"	"3559.8"	"4227.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P29401"	"Transketolase OS=Homo sapiens OX=9606 GN=TKT PE=1 SV=3"	"0.000"	""	"22"	"12"	"25"	"12"	"623"	"67.8"	"7.66"	"4175.42"	"61.55"	"7"	"11"	"other metabolic processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle"	"other molecular function"	"Pf00456, Pf02779, Pf02780"	"7086"	"ENSG00000163931"	"TKT"	"A8K089; B4DE31; E7EPA7; hsa:7086; P29401; Q8TBA3; Q96HH3"	"Pentose phosphate metabolism; VEGFA-VEGFR2 signaling; Metabolic reprogramming in colon cancer; Thiamine metabolic pathways"	"NFE2L2 regulates pentose phosphate pathway genes; Pentose phosphate pathway; Insulin effects increased synthesis of Xylulose-5-Phosphate"	"7"	"0"	"310.0"	"250.0"	"411.9"	"339.8"	"373.0"	"370.8"	"507.3"	"1188.7"	"1243.5"	"5990.9"	"11513.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UQ35"	"Serine/arginine repetitive matrix protein 2 OS=Homo sapiens OX=9606 GN=SRRM2 PE=1 SV=2"	"0.000"	""	"8"	"16"	"29"	"16"	"2752"	"299.4"	"12.06"	"4754.48"	"61.50"	"13"	"15"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf08312"	"23524"	"ENSG00000167978"	"SRRM2"	"A6NKB9; D3DU97; hsa:23524; O15038; O94803; Q6NSL3; Q6PIM3; Q6PK40; Q8IW17; Q96GY7; Q9P0G1; Q9UHA8; Q9UQ35; Q9UQ36; Q9UQ37; Q9UQ38; Q9UQ40"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"1409.3"	"1130.6"	"1365.7"	"1362.3"	"1229.4"	"1214.1"	"1582.4"	"2387.3"	"2179.1"	"5859.1"	"9130.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96AC1"	"Fermitin family homolog 2 OS=Homo sapiens OX=9606 GN=FERMT2 PE=1 SV=1"	"0.000"	""	"21"	"11"	"26"	"11"	"680"	"77.8"	"6.70"	"5585.05"	"61.46"	"8"	"10"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00169, Pf00373, Pf18124"	"10979"	"ENSG00000073712"	"FERMT2"	"B5TJY2; hsa:10979; Q14840; Q86TY7; Q96AC1"	""	"RAC1 GTPase cycle; RAC3 GTPase cycle; Cell-extracellular matrix interactions"	"3"	"0"	"196.9"	"134.3"	"235.6"	"197.2"	"220.4"	"260.6"	"435.4"	"1827.0"	"2142.9"	"6599.9"	"9929.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86XP3"	"ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1"	"0.000"	""	"22"	"19"	"34"	"19"	"938"	"102.9"	"7.02"	"6917.78"	"61.29"	"16"	"17"	"other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"11325"	"ENSG00000198231"	"DDX42"	"A6NML1; A8KA43; hsa:11325; O75619; Q68G51; Q86XP3; Q96BK1; Q96HR7; Q9Y3V8"	""	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"2"	"0"	"2098.2"	"2012.9"	"1901.1"	"1902.6"	"1857.2"	"1820.3"	"2365.4"	"2972.4"	"2769.3"	"4550.2"	"5844.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11908"	"Ribose-phosphate pyrophosphokinase 2 OS=Homo sapiens OX=9606 GN=PRPS2 PE=1 SV=2"	"0.000"	""	"43"	"14"	"30"	"4"	"318"	"34.7"	"6.61"	"6048.28"	"60.92"	"12"	"13"	"other metabolic processes;other biological processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf13793, Pf14572"	"5634"	"ENSG00000101911"	"PRPS2"	"hsa:5634; P11908; Q0VDH9; Q0VDI0; Q15245; Q2TAK7"	""	"5-Phosphoribose 1-diphosphate biosynthesis"	"1"	"0"	"309.3"	"209.1"	"354.6"	"306.0"	"262.4"	"322.0"	"458.6"	"1320.1"	"1265.8"	"3021.4"	"4286.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49959"	"Double-strand break repair protein MRE11 OS=Homo sapiens OX=9606 GN=MRE11 PE=1 SV=3"	"0.000"	""	"20"	"13"	"33"	"13"	"708"	"80.5"	"5.90"	"7338.99"	"60.63"	"13"	"12"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00149, Pf04152"	"4361"	"ENSG00000020922"	"MRE11"	"B3KTC7; hsa:4361; O43475; P49959"	"miRNA regulation of DNA damage response; Homologous recombination; DDX1 as a regulatory component of the Drosha microprocessor; ATM signaling in development and disease ; Breast cancer pathway; Joubert syndrome; DNA repair pathways, full network; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; Neurogenesis regulation in the olfactory epithelium; DNA damage response"	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; Meiotic recombination; DNA Damage/Telomere Stress Induced Senescence; Nonhomologous End-Joining (NHEJ); Resolution of D-loop Structures through Holliday Junction Intermediates; Regulation of TP53 Activity through Phosphorylation; Presynaptic phase of homologous DNA pairing and strand exchange; Cytosolic sensors of pathogen-associated DNA ; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; HDR through MMEJ (alt-NHEJ); Sensing of DNA Double Strand Breaks; IRF3-mediated induction of type I IFN"	"32"	"0"	"1232.6"	"825.6"	"1217.9"	"1162.1"	"1013.8"	"1074.8"	"1454.8"	"2533.2"	"2356.1"	"5607.3"	"8658.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35637"	"RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1"	"0.000"	""	"18"	"11"	"27"	"8"	"526"	"53.4"	"9.36"	"6019.13"	"60.31"	"8"	"8"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00641"	"2521"	"ENSG00000089280"	"FUS"	"hsa:2521; P35637; Q9H4A8"	"MECP2 and associated Rett syndrome; mRNA processing"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"4"	"3"	"2438.2"	"2210.1"	"2300.8"	"1930.0"	"2038.4"	"2041.7"	"2751.9"	"3881.3"	"3261.9"	"6349.3"	"9429.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UHX1"	"Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1"	"0.000"	""	"31"	"15"	"31"	"15"	"559"	"59.8"	"5.29"	"5865.52"	"60.16"	"12"	"12"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"22827"	"ENSG00000179950; ENSG00000274081"	"PUF60"	"A8K8K8; hsa:22827; Q969E7; Q96D94; Q96H63; Q99628; Q9NZA0; Q9UHX1; Q9UJY7"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"1247.0"	"858.8"	"1139.9"	"1064.0"	"1000.5"	"943.1"	"1336.8"	"2712.8"	"3021.8"	"8247.3"	"13358.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14868"	"Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2"	"0.000"	""	"37"	"16"	"34"	"16"	"501"	"57.1"	"6.55"	"6770.61"	"59.75"	"15"	"15"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00152, Pf01336"	"1615"	"ENSG00000115866"	"DARS1"	"A8K3J2; D3DP77; hsa:1615; P14868; Q2TNI3; Q32Q69; Q53HV4; Q53YC5; Q68CR9; Q9BW52"	"Alanine and aspartate metabolism"	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"3"	"0"	"371.8"	"280.2"	"414.5"	"391.7"	"377.9"	"429.2"	"559.3"	"1857.7"	"2050.2"	"6431.9"	"9595.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35908"	"Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2"	"0.000"	""	"23"	"13"	"33"	"9"	"639"	"65.4"	"8.00"	"5921.74"	"59.58"	"13"	"13"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;cytosol;cytoskeleton;other cell component"	"bone, tooth or skin structural activity;cytoskeletal activity"	"Pf00038, Pf16208"	"3849"	"ENSG00000172867"	"KRT2"	"hsa:3849; P35908; Q4VAQ2"	""	"Formation of the cornified envelope"	"2"	"2"	"733.9"	"649.5"	"2877.7"	"1600.9"	"2572.3"	"1059.3"	"1364.3"	"3489.2"	"4167.3"	"3202.9"	"4116.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q07955"	"Serine/arginine-rich splicing factor 1 OS=Homo sapiens OX=9606 GN=SRSF1 PE=1 SV=2"	"0.000"	""	"48"	"15"	"30"	"15"	"248"	"27.7"	"10.36"	"4886.12"	"59.37"	"12"	"13"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6426"	"ENSG00000136450"	"SRSF1"	"B2R6Z7; D3DTZ3; hsa:6426; Q07955; Q13809"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"7"	"0"	"2826.5"	"2761.4"	"2052.6"	"2117.3"	"2131.5"	"2083.2"	"2896.3"	"3397.2"	"2922.0"	"4603.6"	"6585.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P78347"	"General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2"	"0.000"	""	"18"	"16"	"29"	"16"	"998"	"112.3"	"6.39"	"5802.86"	"59.33"	"12"	"15"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02946"	"2969"	"ENSG00000263001"	"GTF2I"	"hsa:2969; O14743; O15359; O43546; O43588; O43589; P78347; Q75M85; Q75M86; Q75M87; Q75M88; Q86U51; Q9BSZ4"	"B cell receptor signaling pathway; 7q11.23 copy number variation syndrome; Genetic causes of porto-sinusoidal vascular disease"	""	"3"	"0"	"847.5"	"665.3"	"908.1"	"804.4"	"753.7"	"798.4"	"1079.7"	"2126.3"	"2185.4"	"5442.9"	"7600.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P2J5"	"Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2"	"0.000"	""	"18"	"16"	"34"	"16"	"1176"	"134.4"	"7.30"	"5725.15"	"59.25"	"12"	"14"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00133, Pf08264"	"51520"	"ENSG00000133706"	"LARS1"	"A2RRR4; A7E266; B4DJ10; hsa:51520; Q2TU79; Q9NSE1; Q9P2J5"	""	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"2"	"0"	"938.1"	"696.4"	"838.9"	"838.7"	"763.6"	"829.1"	"1048.2"	"1857.9"	"1965.5"	"4909.2"	"7371.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49368"	"T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4"	"0.000"	""	"37"	"15"	"24"	"15"	"545"	"60.5"	"6.49"	"3572.16"	"58.85"	"10"	"14"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00118"	"7203"	"ENSG00000163468"	"CCT3"	"A6NE14; hsa:7203; P49368; Q5SZY1; Q9BR64"	"16p11.2 proximal deletion syndrome"	"Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; Folding of actin by CCT/TriC"	"7"	"0"	"333.2"	"247.0"	"388.6"	"359.1"	"308.4"	"329.8"	"435.2"	"1084.6"	"1063.4"	"5316.6"	"11280.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99832"	"T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2"	"0.000"	""	"32"	"13"	"25"	"13"	"543"	"59.3"	"7.65"	"3896.05"	"58.55"	"9"	"11"	"protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00118"	"10574"	"ENSG00000135624"	"CCT7"	"A8K7E6; A8MWI8; B7WNW9; B7Z4T9; B7Z4Z7; hsa:10574; O14871; Q6FI26; Q99832"	"VEGFA-VEGFR2 signaling; 16p11.2 proximal deletion syndrome"	"Formation of tubulin folding intermediates by CCT/TriC; RHOBTB1 GTPase cycle; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; RHOBTB2 GTPase cycle; Folding of actin by CCT/TriC"	"9"	"0"	"298.1"	"216.3"	"332.3"	"294.8"	"258.5"	"282.7"	"380.0"	"897.8"	"910.1"	"4469.5"	"10009.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P31942"	"Heterogeneous nuclear ribonucleoprotein H3 OS=Homo sapiens OX=9606 GN=HNRNPH3 PE=1 SV=2"	"0.000"	""	"26"	"10"	"26"	"9"	"346"	"36.9"	"6.87"	"4057.24"	"58.47"	"7"	"9"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf00076"	"3189"	"ENSG00000096746"	"HNRNPH3"	"A8K682; B3KRE1; hsa:3189; P31942; Q9BSX1; Q9NP53; Q9NP96; Q9NPA7; Q9NPI4; Q9UFU4; Q9Y4J5"	""	""	"0"	"0"	"726.6"	"536.6"	"669.6"	"629.9"	"607.7"	"594.6"	"842.6"	"1121.4"	"1059.7"	"1934.3"	"2855.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62258"	"14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1"	"0.000"	""	"57"	"13"	"36"	"11"	"255"	"29.2"	"4.74"	"7603.99"	"58.43"	"11"	"12"	"stress response;transport;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00244"	"7531"	"ENSG00000108953; ENSG00000274474"	"YWHAE"	"B3KY71; D3DTH5; hsa:7531; P29360; P42655; P62258; Q4VJB6; Q53XZ5; Q63631; Q7M4R4"	"Cell cycle; Myometrial relaxation and contraction pathways; VEGFA-VEGFR2 signaling; Calcium regulation in cardiac cells; 17p13.3 (YWHAE) copy number variation; Sudden infant death syndrome (SIDS) susceptibility pathways"	"TP53 Regulates Metabolic Genes; RAB GEFs exchange GTP for GDP on RABs; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Recruitment of NuMA to mitotic centrosomes; Regulation of HSF1-mediated heat shock response; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Signaling by Hippo; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models; HSF1 activation; NADE modulates death signalling; Activation of BAD and translocation to mitochondria"	"26"	"4"	"2425.7"	"2138.0"	"2066.3"	"1905.5"	"1853.4"	"2194.5"	"2855.1"	"3999.7"	"3829.3"	"7199.5"	"9953.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50570"	"Dynamin-2 OS=Homo sapiens OX=9606 GN=DNM2 PE=1 SV=2"	"0.000"	""	"20"	"13"	"28"	"9"	"870"	"98.0"	"7.44"	"4857.87"	"58.09"	"10"	"12"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00169, Pf00350, Pf01031, Pf02212"	"1785"	"ENSG00000079805"	"DNM2"	"A8K1B6; E7EV30; E9PEQ4; hsa:1785; K7ESI9; P50570; Q5I0Y0; Q7Z5S3; Q9UPH4"	"Synaptic vesicle pathway; Fragile X syndrome; Intracellular trafficking proteins involved in CMT neuropathy"	"Recycling pathway of L1; MHC class II antigen presentation; Clathrin-mediated endocytosis; Lysosome Vesicle Biogenesis; NGF-stimulated transcription; Golgi Associated Vesicle Biogenesis; Toll Like Receptor 4 (TLR4) Cascade; NOSTRIN mediated eNOS trafficking; Retrograde neurotrophin signalling; Formation of annular gap junctions"	"14"	"4"	"494.3"	"367.3"	"554.4"	"511.2"	"504.3"	"567.4"	"788.9"	"1819.3"	"1813.7"	"4360.2"	"6680.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P41252"	"Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2"	"0.000"	""	"15"	"16"	"34"	"16"	"1262"	"144.4"	"6.15"	"7528.44"	"58.08"	"14"	"14"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00133, Pf08264, Pf19302"	"3376"	"ENSG00000196305"	"IARS1"	"A8KAE9; hsa:3376; P41252; Q5TCD0; Q7Z3T4; Q9H588"	"Amino acid metabolism"	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"3"	"0"	"848.9"	"656.1"	"820.0"	"822.5"	"750.6"	"773.8"	"1038.6"	"2244.0"	"2420.7"	"7657.1"	"11647.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00291"	"Huntingtin-interacting protein 1 OS=Homo sapiens OX=9606 GN=HIP1 PE=1 SV=5"	"0.000"	""	"19"	"16"	"29"	"16"	"1037"	"116.1"	"5.30"	"5171.10"	"58.01"	"13"	"14"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf01608, Pf07651, Pf16515"	"3092"	"ENSG00000127946"	"HIP1"	"B4E3I7; E7ES17; hsa:3092; O00291; O00328; Q2TB58; Q8TDL4; V5LU97"	"DYRK1A involvement regarding cell proliferation in brain development; 5q35 copy number variation"	"Clathrin-mediated endocytosis; ALK mutants bind TKIs; Signaling by ALK fusions and activated point mutants"	"5"	"0"	"331.9"	"252.1"	"414.0"	"362.8"	"378.5"	"388.2"	"487.2"	"2164.9"	"2287.2"	"6501.7"	"8806.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25705"	"ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1"	"0.000"	""	"24"	"11"	"30"	"10"	"553"	"59.7"	"9.13"	"5988.57"	"57.82"	"9"	"10"	"other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;transporter activity;other molecular function"	"Pf00006, Pf00306, Pf02874"	"498"	"ENSG00000152234"	"ATP5F1A"	"A8K092; B4DY56; hsa:498; K7ENP3; P25705; Q53XX6; Q8IXV2; Q96FB4; Q96HW2; Q96IR6; Q9BTV8"	"Electron transport chain: OXPHOS system in mitochondria; 7q11.23 copy number variation syndrome; Oxidative phosphorylation"	"Mitochondrial protein import; Cristae formation; Formation of ATP by chemiosmotic coupling"	"6"	"0"	"596.7"	"452.4"	"641.6"	"570.9"	"528.4"	"595.2"	"761.6"	"1699.9"	"1752.3"	"5103.4"	"6896.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P31948"	"Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1"	"0.000"	""	"27"	"14"	"27"	"14"	"543"	"62.6"	"6.80"	"4318.86"	"57.72"	"9"	"14"	"other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00515, Pf13181, Pf17830"	"10963"	"ENSG00000168439"	"STIP1"	"B4DM70; F5H0T1; G3XAD8; hsa:10963; P31948; Q3ZCU9; Q5TZU9"	"VEGFA-VEGFR2 signaling"	"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; RND1 GTPase cycle"	"3"	"0"	"882.4"	"742.2"	"962.2"	"832.6"	"830.4"	"839.6"	"1101.4"	"2247.3"	"2005.9"	"9466.4"	"19508.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NYF8"	"Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2"	"0.000"	""	"20"	"18"	"35"	"18"	"920"	"106.1"	"9.98"	"7104.39"	"57.51"	"16"	"16"	"stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf15440"	"9774"	"ENSG00000029363"	"BCLAF1"	"A2RU75; B7ZM58; E1P586; hsa:9774; Q14673; Q86WU6; Q86WY0; Q9NYF8"	"Interactome of polycomb repressive complex 2 (PRC2)"	""	"1"	"0"	"2201.6"	"1803.9"	"2013.9"	"1851.6"	"1792.6"	"1886.7"	"2420.8"	"3189.7"	"3087.9"	"6867.8"	"11438.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BVJ6"	"U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1"	"0.000"	""	"24"	"16"	"31"	"16"	"771"	"87.9"	"7.87"	"6567.89"	"57.34"	"16"	"15"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf04615"	"10813"	"ENSG00000156697"	"UTP14A"	"A8K7A3; A8MVQ1; B4DQ08; E9PEL7; hsa:10813; Q5JYF1; Q9BVJ6"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"1622.1"	"1160.1"	"1637.2"	"1599.9"	"1474.2"	"1528.9"	"1969.6"	"2646.8"	"2374.5"	"3851.5"	"3898.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49756"	"RNA-binding protein 25 OS=Homo sapiens OX=9606 GN=RBM25 PE=1 SV=3"	"0.000"	""	"17"	"13"	"28"	"13"	"843"	"100.1"	"6.32"	"4942.04"	"57.29"	"11"	"12"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf01480"	"58517"	"ENSG00000119707"	"RBM25"	"A0PJL9; B2RNA8; B3KT03; hsa:58517; P49756; Q2TA72; Q5XJ17; Q6P665; Q9H6A1; Q9UEQ5; Q9UIE9"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"960.1"	"765.6"	"876.8"	"829.1"	"767.9"	"854.4"	"1117.3"	"1909.7"	"1954.3"	"5221.3"	"7933.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P33992"	"DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5"	"0.000"	""	"21"	"13"	"30"	"13"	"734"	"82.2"	"8.37"	"6154.74"	"57.16"	"12"	"11"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf14551, Pf17207, Pf17855"	"4174"	"ENSG00000100297"	"MCM5"	"hsa:4174; O60785; P33992; Q14578; Q9BTJ4; Q9BWL8"	"Cell cycle; Ciliary landscape; G1 to S cell cycle control; DNA replication"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"10"	"0"	"1016.3"	"736.9"	"1135.4"	"1068.3"	"1010.8"	"969.4"	"1478.8"	"2495.3"	"2417.5"	"5564.3"	"8050.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P47897"	"Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1"	"0.000"	""	"20"	"12"	"28"	"11"	"775"	"87.7"	"7.15"	"5220.42"	"56.70"	"9"	"12"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;mitochondrion;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00749, Pf03950, Pf04557, Pf04558"	"5859"	"ENSG00000172053"	"QARS1"	"B4DWJ2; hsa:5859; P47897"	""	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation; Mitochondrial tRNA aminoacylation"	"3"	"0"	"374.8"	"263.1"	"347.4"	"352.1"	"320.6"	"356.4"	"445.0"	"880.1"	"940.4"	"2807.0"	"4447.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75131"	"Copine-3 OS=Homo sapiens OX=9606 GN=CPNE3 PE=1 SV=1"	"0.000"	""	"24"	"10"	"20"	"10"	"537"	"60.1"	"5.85"	"2093.05"	"56.32"	"5"	"10"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;kinase activity;other molecular function"	"Pf00168, Pf07002"	"8895"	"ENSG00000085719"	"CPNE3"	"A8KA47; hsa:8895; O75131; Q8IYA1"	""	"Neutrophil degranulation; Glycerophospholipid biosynthesis"	"2"	"0"	"294.9"	"203.5"	"332.2"	"287.3"	"285.5"	"306.5"	"375.5"	"644.0"	"654.2"	"2325.9"	"10820.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13123"	"Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3"	"0.000"	""	"31"	"21"	"37"	"21"	"557"	"65.6"	"6.64"	"6821.03"	"55.70"	"18"	"17"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf07807, Pf07808"	"3550"	"ENSG00000113141"	"IK"	"hsa:3550; Q13123; Q6IPD8"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"2940.9"	"2412.5"	"2790.3"	"2653.2"	"2401.2"	"2483.8"	"3208.3"	"3939.9"	"3728.7"	"5552.6"	"7433.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NZW5"	"MAGUK p55 subfamily member 6 OS=Homo sapiens OX=9606 GN=MPP6 PE=1 SV=2"	"0.000"	""	"26"	"14"	"29"	"12"	"540"	"61.1"	"6.18"	"5349.47"	"55.22"	"13"	"13"	"cell organization and biogenesis"	"plasma membrane;other membranes;other cell component"	""	"Pf00595, Pf00625, Pf02828, Pf07653"	"51678"	"ENSG00000105926"	"PALS2"	"A4D157; hsa:51678; Q9H0E1; Q9NZW5"	""	""	"0"	"2"	"900.5"	"631.8"	"826.0"	"770.5"	"741.4"	"768.2"	"1056.5"	"2740.5"	"2995.7"	"8844.7"	"11669.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16181"	"Septin-7 OS=Homo sapiens OX=9606 GN=SEPTIN7 PE=1 SV=2"	"0.000"	""	"29"	"12"	"30"	"11"	"437"	"50.6"	"8.63"	"6478.63"	"55.20"	"11"	"11"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00735"	"989"	"ENSG00000122545"	"SEPTIN7"	"hsa:989; Q16181; Q52M76; Q6NX50"	""	"MAPK6/MAPK4 signaling"	"1"	"1"	"1190.2"	"865.4"	"1198.3"	"1085.0"	"1067.8"	"1112.0"	"1530.2"	"3693.4"	"3649.1"	"7395.4"	"10032.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UNX4"	"WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1"	"0.000"	""	"21"	"14"	"28"	"14"	"943"	"106.0"	"6.64"	"5116.59"	"54.98"	"12"	"14"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00400, Pf04003, Pf12894"	"10885"	"ENSG00000065183"	"WDR3"	"hsa:10885; Q9UNX4"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"630.1"	"521.8"	"670.7"	"630.8"	"573.2"	"598.5"	"808.9"	"2418.4"	"2576.2"	"4640.9"	"4283.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BSJ8"	"Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1"	"0.000"	""	"16"	"13"	"22"	"13"	"1104"	"122.8"	"5.83"	"3676.92"	"54.54"	"9"	"13"	"cell organization and biogenesis;transport"	"plasma membrane;other membranes;ER/Golgi"	"transporter activity;other molecular function"	"Pf00168, Pf17047"	"23344"	"ENSG00000139641"	"ESYT1"	"A0FGR7; A8K2S2; hsa:23344; O94848; Q6PJN4; Q9BSJ8; Q9H6J1; Q9H6W2; Q9Y416"	""	"RHOG GTPase cycle; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOD GTPase cycle; Glycosphingolipid metabolism; RHOF GTPase cycle"	"7"	"0"	"280.5"	"232.2"	"464.4"	"448.4"	"558.4"	"1002.3"	"1422.9"	"2746.6"	"2967.3"	"5099.6"	"6292.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UH65"	"Switch-associated protein 70 OS=Homo sapiens OX=9606 GN=SWAP70 PE=1 SV=1"	"0.000"	""	"25"	"15"	"28"	"15"	"585"	"69.0"	"5.87"	"5569.04"	"53.61"	"14"	"14"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00169"	"23075"	"ENSG00000133789"	"SWAP70"	"D3DQV1; hsa:23075; O75135; Q7LCY6; Q9P061; Q9P0Z8; Q9UH65"	""	"RAC1 GTPase cycle; RAC3 GTPase cycle; RAC2 GTPase cycle"	"3"	"0"	"448.7"	"322.8"	"518.3"	"474.4"	"467.9"	"614.5"	"943.1"	"3774.6"	"3833.3"	"10272.6"	"11915.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BXJ9"	"N-alpha-acetyltransferase 15, NatA auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA15 PE=1 SV=1"	"0.000"	""	"17"	"15"	"26"	"11"	"866"	"101.2"	"7.42"	"3594.42"	"53.04"	"9"	"15"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity"	"Pf12569, Pf13181"	"80155"	"ENSG00000164134"	"NAA15"	"D3DNY6; hsa:80155; Q52LG9; Q8IWH4; Q8NEV2; Q9BXJ9; Q9H8P6"	""	""	"0"	"4"	"356.2"	"249.1"	"372.8"	"366.8"	"357.4"	"344.9"	"454.7"	"1522.1"	"1563.0"	"8424.2"	"12814.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11586"	"C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=3"	"0.000"	""	"19"	"14"	"27"	"14"	"935"	"101.5"	"7.30"	"4873.84"	"52.53"	"12"	"13"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"955.8"	"679.4"	"823.3"	"795.5"	"672.2"	"723.3"	"984.3"	"1623.3"	"1552.1"	"3605.5"	"5354.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H9Y6"	"DNA-directed RNA polymerase I subunit RPA2 OS=Homo sapiens OX=9606 GN=POLR1B PE=1 SV=2"	"0.000"	""	"13"	"12"	"30"	"12"	"1135"	"128.1"	"7.83"	"5811.06"	"52.47"	"12"	"12"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00562, Pf04560, Pf04561, Pf04563, Pf04565, Pf06883"	"84172"	"ENSG00000125630"	"POLR1B"	"B7Z6Y7; B7Z823; F5GZX4; F8W898; hsa:84172; Q2TAM4; Q585T5; Q6ZRR2; Q9H9D3; Q9H9Y6"	"Pyrimidine metabolism; Eukaryotic transcription initiation; 2q13 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"8"	"0"	"347.1"	"248.1"	"397.0"	"358.1"	"350.3"	"371.9"	"495.0"	"1602.6"	"1794.7"	"4422.3"	"5859.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P40227"	"T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3"	"0.000"	""	"33"	"15"	"28"	"15"	"531"	"58.0"	"6.68"	"4821.39"	"51.82"	"9"	"13"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00118"	"908"	"ENSG00000146731"	"CCT6A"	"A6NCD2; hsa:908; P40227; Q3KP28; Q75LP4; Q96S46"	"16p11.2 proximal deletion syndrome"	"Formation of tubulin folding intermediates by CCT/TriC; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; RHOBTB2 GTPase cycle; Folding of actin by CCT/TriC"	"7"	"0"	"483.6"	"370.2"	"617.3"	"509.2"	"491.5"	"472.5"	"674.3"	"1576.6"	"1551.6"	"7816.5"	"16824.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13838"	"Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1"	"0.000"	""	"27"	"13"	"27"	"5"	"428"	"49.0"	"5.67"	"4602.06"	"51.71"	"9"	"12"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"7919"	"ENSG00000198563; ENSG00000215425; ENSG00000225073; ENSG00000225859; ENSG00000229496; ENSG00000230624; ENSG00000235439"	"DDX39B"	"B0S8C0; hsa:7919; O43496; Q0EFA1; Q13838; Q2L6F9; Q53GL9; Q5RJ64; Q5RJ66; Q5ST94; Q5STB4; Q5STB5; Q5STB7; Q5STB8; Q5STU4; Q5STU5; Q5STU6; Q5STU8; Q71V76"	""	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; RHOBTB2 GTPase cycle; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"5"	"8"	"780.3"	"594.2"	"860.3"	"789.4"	"721.3"	"727.2"	"1035.9"	"1679.0"	"1582.9"	"3600.1"	"7719.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63104"	"14-3-3 protein zeta/delta OS=Homo sapiens OX=9606 GN=YWHAZ PE=1 SV=1"	"0.000"	""	"45"	"10"	"27"	"8"	"245"	"27.7"	"4.79"	"5285.47"	"51.40"	"8"	"10"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00244"	"7534"	"ENSG00000164924"	"YWHAZ"	"A8K1N0; B7Z465; hsa:7534; P29213; P29312; P63104; Q32P43; Q5XJ08; Q6GPI2; Q6IN74; Q6NUR9; Q6P3U9; Q86V33"	"Cell cycle; Prolactin signaling pathway; Pathogenic Escherichia coli infection; Myometrial relaxation and contraction pathways; Hepatitis B infection; GDNF signaling; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Deactivation of the beta-catenin transactivating complex; Translocation of SLC2A4 (GLUT4) to the plasma membrane; RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Regulation of localization of FOXO transcription factors; Negative regulation of NOTCH4 signaling; Interleukin-3, Interleukin-5 and GM-CSF signaling; TP53 Regulates Metabolic Genes; NOTCH4 Activation and Transmission of Signal to the Nucleus; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; Rap1 signalling; KSRP (KHSRP) binds and destabilizes mRNA; GP1b-IX-V activation signalling; Activation of BAD and translocation to mitochondria"	"23"	"0"	"1432.3"	"1125.4"	"1234.8"	"1220.7"	"1140.3"	"1150.1"	"1538.2"	"2113.1"	"2010.4"	"3365.9"	"4340.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63279"	"SUMO-conjugating enzyme UBC9 OS=Homo sapiens OX=9606 GN=UBE2I PE=1 SV=1"	"0.000"	""	"80"	"9"	"22"	"9"	"158"	"18.0"	"8.66"	"4826.18"	"50.86"	"7"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00179"	"7329"	"ENSG00000103275"	"UBE2I"	"D3DU69; hsa:7329; P50550; P63279; Q15698; Q59GX1; Q86VB3"	"Androgen receptor signaling pathway; TAR syndrome"	"SUMOylation of RNA binding proteins; Meiotic synapsis; SUMOylation of DNA damage response and repair proteins; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Processing of DNA double-strand break ends; Formation of Incision Complex in GG-NER; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SUMOylation of ubiquitinylation proteins; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of DNA replication proteins; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; SUMOylation of intracellular receptors; Vitamin D (calciferol) metabolism; SUMOylation of transcription factors; Postmitotic nuclear pore complex (NPC) reformation; Negative regulation of activity of TFAP2 (AP-2) family transcription factors; Maturation of nucleoprotein; SUMOylation of immune response proteins; SUMOylation of nuclear envelope proteins; Maturation of nucleoprotein; SUMO is transferred from E1 to E2 (UBE2I, UBC9)"	"25"	"0"	"832.7"	"710.2"	"862.5"	"791.7"	"777.8"	"885.8"	"1354.8"	"3220.6"	"3165.9"	"7167.3"	"10120.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UNF0"	"Protein kinase C and casein kinase substrate in neurons protein 2 OS=Homo sapiens OX=9606 GN=PACSIN2 PE=1 SV=2"	"0.000"	""	"29"	"10"	"22"	"10"	"486"	"55.7"	"5.20"	"4410.61"	"50.66"	"8"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00018, Pf00611"	"11252"	"ENSG00000100266"	"PACSIN2"	"hsa:11252; O95921; Q96HV9; Q9H0D3; Q9NPN1; Q9UNF0; Q9Y4V2"	""	"Clathrin-mediated endocytosis"	"1"	"0"	"446.2"	"333.0"	"459.2"	"428.1"	"397.2"	"442.3"	"572.0"	"1602.4"	"1563.4"	"6459.0"	"9983.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35241"	"Radixin OS=Homo sapiens OX=9606 GN=RDX PE=1 SV=1"	"0.000"	""	"24"	"19"	"37"	"7"	"583"	"68.5"	"6.37"	"6994.66"	"50.66"	"19"	"16"	"cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf00769, Pf09379, Pf09380, Pf20492"	"5962"	"ENSG00000137710"	"RDX"	"A7YIJ8; A7YIK0; A7YIK3; B7Z9U6; F5H1A7; hsa:5962; P35241; Q86Y61"	"Regulation of actin cytoskeleton"	"Recycling pathway of L1; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea"	"4"	"2"	"1274.6"	"1106.2"	"1221.7"	"1157.7"	"1211.4"	"1289.2"	"1532.2"	"2304.4"	"2118.9"	"3099.4"	"3055.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P16152"	"Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3"	"0.000"	""	"46"	"11"	"24"	"11"	"277"	"30.4"	"8.32"	"4564.86"	"50.63"	"10"	"11"	"other metabolic processes;other biological processes"	"cytosol"	"other molecular function"	"Pf00106"	"873"	"ENSG00000159228"	"CBR1"	"B2RBZ7; B4DFK7; hsa:873; P16152; Q3LHW8"	"Nuclear receptors meta-pathway; NRF2 pathway; Prostaglandin synthesis and regulation"	"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)"	"4"	"0"	"276.3"	"219.2"	"321.9"	"299.2"	"278.8"	"338.2"	"478.5"	"1646.5"	"1754.9"	"5096.4"	"8046.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L014"	"Probable ATP-dependent RNA helicase DDX46 OS=Homo sapiens OX=9606 GN=DDX46 PE=1 SV=2"	"0.000"	""	"12"	"13"	"30"	"13"	"1031"	"117.3"	"9.29"	"6280.97"	"50.63"	"13"	"12"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"other membranes;nucleus"	"other molecular function"	"Pf00270, Pf00271"	"9879"	"ENSG00000145833"	"DDX46"	"hsa:9879; O94894; Q7L014; Q96EI0; Q9Y658"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"1009.1"	"852.8"	"928.2"	"880.8"	"884.4"	"874.8"	"1106.5"	"2677.4"	"2795.7"	"8117.5"	"12062.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42166"	"Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2"	"0.000"	""	"25"	"12"	"21"	"5"	"694"	"75.4"	"7.66"	"4030.39"	"50.61"	"9"	"11"	""	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03020, Pf08198, Pf11560"	"7112"	"ENSG00000120802"	"TMPO"	"P08918; P08919; P42166; Q14860; Q16295"	"Envelope proteins and their potential roles in EDMD physiopathology; Overlap between signal transduction pathways contributing to LMNA laminopathies"	""	"2"	"7"	"865.7"	"716.1"	"735.0"	"681.2"	"750.3"	"725.1"	"978.1"	"2359.5"	"2342.6"	"4718.3"	"6172.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q71DI3"	"Histone H3.2 OS=Homo sapiens OX=9606 GN=H3C15 PE=1 SV=3"	"0.000"	""	"55"	"9"	"25"	"1"	"136"	"15.4"	"11.27"	"4154.19"	"50.60"	"7"	"9"	"cell organization and biogenesis"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125"	"126961; 333932; 653604"	"ENSG00000183598; ENSG00000203811; ENSG00000203852"	"H3C13; H3C14; H3C15"	"A2BDF6; A6NFS4; hsa:126961; hsa:333932; hsa:653604; Q6B053; Q71DI3"	"Histone modifications; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma"	"Amyloid fiber formation; HCMV Late Events; RUNX1 regulates transcription of genes involved in differentiation of HSCs; HCMV Early Events; Transcriptional regulation by small RNAs; B-WICH complex positively regulates rRNA expression; Formation of the beta-catenin:TCF transactivating complex; Oxidative Stress Induced Senescence; HDACs deacetylate histones; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Pre-NOTCH Transcription and Translation; Senescence-Associated Secretory Phenotype (SASP); RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; HATs acetylate histones; RNA Polymerase I Promoter Escape; Meiotic recombination; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Condensation of Prophase Chromosomes; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis; Interleukin-7 signaling; Factors involved in megakaryocyte development and platelet production; RMTs methylate histone arginines; HDMs demethylate histones; PKMTs methylate histone lysines"	"36"	"0"	"6.1"	"4.5"	"2.3"	"6.7"	"4.8"	"4.3"	"12.2"	"14.5"	"13.4"	"55.7"	"117.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96DI7"	"U5 small nuclear ribonucleoprotein 40 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP40 PE=1 SV=1"	"0.000"	""	"49"	"12"	"26"	"12"	"357"	"39.3"	"8.10"	"4532.70"	"50.38"	"9"	"12"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf00400"	"9410"	"ENSG00000060688"	"SNRNP40"	"B4DQJ1; hsa:9410; O75938; O95320; Q96DI7"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"3"	"0"	"808.8"	"636.5"	"798.3"	"725.0"	"701.4"	"717.7"	"977.9"	"1846.7"	"1778.6"	"4999.0"	"7793.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15046"	"Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3"	"0.000"	""	"20"	"11"	"23"	"11"	"597"	"68.0"	"6.35"	"3805.60"	"50.37"	"9"	"11"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00152, Pf01336"	"3735"	"ENSG00000065427"	"KARS1"	"A8MSK1; D3DUK4; hsa:3735; O14946; Q15046; Q96J25; Q9HB23"	""	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation; Mitochondrial tRNA aminoacylation"	"3"	"0"	"807.0"	"634.6"	"775.6"	"785.2"	"725.6"	"730.0"	"1022.1"	"2408.4"	"2309.4"	"6130.2"	"7033.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62318"	"Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1"	"0.000"	""	"56"	"7"	"18"	"7"	"126"	"13.9"	"10.32"	"3131.65"	"50.19"	"4"	"6"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01423"	"6634"	"ENSG00000100028"	"SNRPD3"	"B4DJP7; B5BU13; hsa:6634; P43331; P62318"	"mRNA processing"	"mRNA Splicing - Major Pathway; RNA Polymerase II Transcription Termination; SARS-CoV-2 modulates host translation machinery; snRNP Assembly; mRNA Splicing - Minor Pathway; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"8"	"0"	"1290.9"	"1045.2"	"1402.3"	"1209.2"	"1138.7"	"1039.3"	"1438.7"	"1964.1"	"1660.5"	"3116.9"	"4667.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96P16"	"Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1"	"0.000"	""	"40"	"13"	"29"	"11"	"312"	"35.7"	"7.55"	"5932.59"	"50.11"	"11"	"11"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf04818, Pf16566"	"55197"	"ENSG00000141425"	"RPRD1A"	"A8KA42; B2RBA3; hsa:55197; Q7Z5G8; Q96FY9; Q96P16; Q9NVL4"	""	"RNA polymerase II transcribes snRNA genes"	"1"	"2"	"1981.1"	"1386.3"	"1883.9"	"1717.1"	"1430.3"	"1645.3"	"2419.4"	"3125.2"	"2839.5"	"4749.0"	"6055.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96AE4"	"Far upstream element-binding protein 1 OS=Homo sapiens OX=9606 GN=FUBP1 PE=1 SV=3"	"0.000"	""	"20"	"13"	"31"	"9"	"644"	"67.5"	"7.61"	"5796.04"	"50.01"	"13"	"12"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00013, Pf09005"	"8880"	"ENSG00000162613"	"FUBP1"	"hsa:8880; Q12828; Q96AE4"	""	""	"0"	"0"	"979.6"	"863.4"	"970.3"	"882.5"	"951.3"	"961.8"	"1243.0"	"1551.6"	"1462.2"	"2542.8"	"3542.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62805"	"Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2"	"0.000"	""	"60"	"10"	"24"	"10"	"103"	"11.4"	"11.36"	"4805.77"	"49.91"	"10"	"8"	"cell organization and biogenesis;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf15511"	"121504; 554313; 8294; 8359; 8360; 8361; 8362; 8363; 8364; 8365; 8366; 8367; 8368; 8370"	"ENSG00000158406; ENSG00000197061; ENSG00000197238; ENSG00000197837; ENSG00000270276; ENSG00000270882; ENSG00000273542; ENSG00000274618; ENSG00000275126; ENSG00000276180; ENSG00000276966; ENSG00000277157; ENSG00000278637; ENSG00000278705"	"H4C1; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9"	"A2VCL0; hsa:121504; hsa:554313; hsa:8294; hsa:8359; hsa:8360; hsa:8361; hsa:8362; hsa:8363; hsa:8364; hsa:8365; hsa:8366; hsa:8367; hsa:8368; hsa:8370; P02304; P02305; P62805; Q6DRA9; Q6FGB8; Q6NWP7"	"Gastric cancer network 1; Histone modifications; 22q11.2 copy number variation syndrome; Male infertility; Type II interferon signaling"	"HDACs deacetylate histones; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; RUNX1 regulates transcription of genes involved in differentiation of HSCs; HCMV Late Events; HCMV Early Events; SUMOylation of chromatin organization proteins; Transcriptional regulation by small RNAs; Amyloid fiber formation; Meiotic synapsis; Deposition of new CENPA-containing nucleosomes at the centromere; B-WICH complex positively regulates rRNA expression; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Formation of the beta-catenin:TCF transactivating complex; Oxidative Stress Induced Senescence; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Pre-NOTCH Transcription and Translation; Senescence-Associated Secretory Phenotype (SASP); RMTs methylate histone arginines; HDMs demethylate histones; PKMTs methylate histone lysines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; HATs acetylate histones; RNA Polymerase I Promoter Escape; Meiotic recombination; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Packaging Of Telomere Ends; Condensation of Prophase Chromosomes; DNA Damage/Telomere Stress Induced Senescence; DNA methylation; Nonhomologous End-Joining (NHEJ); RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis"	"50"	"0"	"1185.6"	"958.3"	"991.8"	"965.1"	"993.2"	"1152.4"	"1440.3"	"1833.2"	"2052.6"	"4112.0"	"6061.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBU9"	"Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1"	"0.000"	""	"22"	"9"	"18"	"9"	"619"	"70.1"	"8.51"	"3321.13"	"49.87"	"7"	"8"	"other metabolic processes;transport"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf02136, Pf03943, Pf09162"	"10482"	"ENSG00000162231"	"NXF1"	"B4E269; hsa:10482; Q99799; Q9UBU9; Q9UQL2"	"mRNA processing"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript"	"5"	"0"	"561.1"	"501.5"	"596.8"	"565.7"	"562.6"	"626.9"	"757.3"	"1046.3"	"1001.6"	"1912.6"	"3068.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P54886"	"Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2"	"0.000"	""	"18"	"12"	"26"	"12"	"795"	"87.2"	"7.12"	"4041.22"	"49.49"	"10"	"12"	"other metabolic processes"	"other membranes;mitochondrion"	"kinase activity;other molecular function"	"Pf00171, Pf00696"	"5832"	"ENSG00000059573"	"ALDH18A1"	"B2R5Q4; B7Z350; B7Z5X8; B7ZLP1; D3DR44; hsa:5832; O95952; P54886; Q3KQU2; Q5T566; Q5T567; Q9UM72"	"Amino acid metabolism"	""	"1"	"0"	"958.5"	"663.4"	"892.3"	"849.7"	"768.8"	"822.4"	"1106.3"	"1804.0"	"1935.0"	"4258.5"	"6256.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92499"	"ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2"	"0.000"	""	"20"	"11"	"25"	"11"	"740"	"82.4"	"7.23"	"5047.64"	"49.47"	"11"	"10"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf00622"	"1653"	"ENSG00000079785"	"DDX1"	"B4DME8; B4DPN6; hsa:1653; Q92499"	"DDX1 as a regulatory component of the Drosha microprocessor; mRNA processing"	"tRNA processing in the nucleus"	"3"	"0"	"1049.1"	"839.2"	"1080.2"	"1002.0"	"991.4"	"929.2"	"1296.3"	"1896.5"	"1779.0"	"3703.8"	"5174.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55196"	"Afadin OS=Homo sapiens OX=9606 GN=AFDN PE=1 SV=3"	"0.000"	""	"10"	"16"	"28"	"16"	"1824"	"206.7"	"6.47"	"5691.52"	"49.38"	"14"	"12"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00498, Pf00595, Pf00788, Pf01843"	"4301"	"ENSG00000130396"	"AFDN"	"hsa:4301; O75087; O75088; O75089; P55196; Q59FP0; Q5TIG6; Q5TIG7; Q9NSN7; Q9NU92"	"VEGFA-VEGFR2 signaling; Ras signaling; 1q21.1 copy number variation syndrome"	""	"3"	"0"	"923.2"	"777.6"	"944.1"	"869.6"	"844.8"	"819.2"	"1107.9"	"2955.0"	"2782.0"	"4993.6"	"5665.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q10570"	"Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2"	"0.000"	""	"13"	"15"	"30"	"15"	"1443"	"160.8"	"6.40"	"5296.63"	"49.35"	"14"	"15"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03178, Pf10433"	"29894"	"ENSG00000071894; ENSG00000285049"	"CPSF1"	"hsa:29894; Q10570; Q96AF0"	"mRNA processing"	"Transport of Mature mRNA Derived from an Intronless Transcript; tRNA processing in the nucleus; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"7"	"0"	"1067.7"	"872.4"	"974.7"	"993.1"	"917.9"	"944.2"	"1291.0"	"2164.7"	"2017.5"	"5198.4"	"7220.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NC51"	"Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2"	"0.000"	""	"28"	"15"	"25"	"15"	"408"	"44.9"	"8.65"	"5309.01"	"49.22"	"12"	"11"	"cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf04774, Pf16174"	"26135"	"ENSG00000142864"	"SERBP1"	"hsa:26135; Q5VU19; Q5VU20; Q5VU22; Q8NC51; Q8WUH0; Q96SE2; Q9BTY3; Q9BUM4; Q9Y367; Q9Y4S3"	"Apoptosis-related network due to altered Notch3 in ovarian cancer"	""	"1"	"0"	"2647.8"	"2281.6"	"2718.8"	"2436.1"	"2666.0"	"2736.8"	"3399.0"	"3708.0"	"3399.2"	"6092.4"	"8952.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86UP2"	"Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1"	"0.000"	""	"11"	"12"	"24"	"12"	"1357"	"156.2"	"5.64"	"4588.85"	"49.18"	"12"	"12"	"transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi"	"cytoskeletal activity"	"Pf05104"	"3895"	"ENSG00000126777"	"KTN1"	"B4DZ88; hsa:3895; Q13999; Q14707; Q15387; Q17RZ5; Q5GGW3; Q86UP2; Q86W57"	"Glucocorticoid receptor pathway; Nuclear receptors meta-pathway"	"RHOA GTPase cycle; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; CDC42 GTPase cycle; RAC1 GTPase cycle; RND2 GTPase cycle; RND3 GTPase cycle; RHOG GTPase cycle; RHO GTPases activate KTN1"	"11"	"0"	"544.5"	"389.9"	"633.6"	"533.2"	"525.0"	"507.3"	"699.5"	"1482.1"	"1477.1"	"3816.9"	"5587.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43395"	"U4/U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2"	"0.000"	""	"20"	"10"	"24"	"10"	"683"	"77.5"	"9.50"	"4911.39"	"48.99"	"8"	"10"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf01480, Pf06544, Pf08572"	"9129"	"ENSG00000117360"	"PRPF3"	"B4DSY9; hsa:9129; O43395; O43446; Q5VT54"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"1305.2"	"1019.5"	"1205.7"	"1155.4"	"1063.5"	"1099.1"	"1396.4"	"2013.5"	"1926.0"	"3604.1"	"5042.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96I24"	"Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2"	"0.000"	""	"25"	"15"	"35"	"12"	"572"	"61.6"	"8.38"	"5911.03"	"48.95"	"13"	"14"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"translational apparatus;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00013"	"8939"	"ENSG00000107164"	"FUBP3"	"A3KFK8; A3KFL0; hsa:8939; Q92946; Q96I24; Q9BVB6"	""	""	"0"	"2"	"2008.3"	"1601.0"	"1941.2"	"1692.4"	"1712.5"	"1727.7"	"2294.7"	"3378.1"	"3257.3"	"6286.8"	"8523.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P68431"	"Histone H3.1 OS=Homo sapiens OX=9606 GN=H3C1 PE=1 SV=2"	"0.000"	""	"55"	"9"	"25"	"1"	"136"	"15.4"	"11.12"	"4154.19"	"48.82"	"7"	"9"	"cell organization and biogenesis;other metabolic processes"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125"	"8350; 8351; 8352; 8353; 8354; 8355; 8356; 8357; 8358; 8968"	"ENSG00000197153; ENSG00000197409; ENSG00000273983; ENSG00000274750; ENSG00000275379; ENSG00000275714; ENSG00000277775; ENSG00000278828; ENSG00000286522; ENSG00000287080"	"H3C1; H3C10; H3C11; H3C12; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8"	"A0PJT7; A5PLR1; hsa:8350; hsa:8351; hsa:8352; hsa:8353; hsa:8354; hsa:8355; hsa:8356; hsa:8357; hsa:8358; hsa:8968; P02295; P02296; P16106; P68431; Q6ISV8; Q6NWP8; Q6NWP9; Q6NXU4; Q71DJ3; Q93081"	"Histone modifications; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma"	"Transcriptional regulation by small RNAs; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; HDACs deacetylate histones; Factors involved in megakaryocyte development and platelet production; HDMs demethylate histones; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; HATs acetylate histones; Oxidative Stress Induced Senescence; Pre-NOTCH Transcription and Translation; Transcriptional regulation of granulopoiesis; Amyloid fiber formation; HCMV Late Events; RUNX1 regulates transcription of genes involved in differentiation of HSCs; HCMV Early Events; B-WICH complex positively regulates rRNA expression; Formation of the beta-catenin:TCF transactivating complex; NoRC negatively regulates rRNA expression; Senescence-Associated Secretory Phenotype (SASP); RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; RNA Polymerase I Promoter Escape; Meiotic recombination; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Defective pyroptosis; Condensation of Prophase Chromosomes; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; RNA Polymerase I Promoter Opening; Interleukin-7 signaling; RMTs methylate histone arginines; PKMTs methylate histone lysines"	"36"	"11"	"2007.6"	"1141.1"	"1736.1"	"1474.5"	"1328.1"	"1522.0"	"2007.8"	"2289.1"	"2243.0"	"4545.1"	"8081.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15366"	"Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1"	"0.000"	""	"33"	"9"	"23"	"3"	"365"	"38.6"	"6.79"	"4727.56"	"48.75"	"7"	"9"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013"	"5094"	"ENSG00000197111"	"PCBP2"	"A8K7X6; B4DXP5; F8VYL7; G3V0E8; hsa:5094; I6L8F9; Q15366; Q32Q82; Q59HD4; Q68Y55; Q6IPF4; Q6PKG5"	"mRNA processing; Ferroptosis; Modulators of TCR signaling and T cell activation"	"mRNA Splicing - Major Pathway; Negative regulators of DDX58/IFIH1 signaling; Processing of Capped Intron-Containing Pre-mRNA; SARS-CoV-1 activates/modulates innate immune responses"	"7"	"8"	"1217.5"	"855.6"	"1215.4"	"1104.6"	"991.3"	"1017.9"	"1481.1"	"2219.5"	"2115.3"	"4617.2"	"6455.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55072"	"Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4"	"0.000"	""	"24"	"16"	"30"	"16"	"806"	"89.3"	"5.26"	"6442.12"	"48.72"	"14"	"13"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"non-structural extracellular;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00004, Pf02359, Pf02933, Pf09336, Pf17862"	"7415"	"ENSG00000165280"	"VCP"	"B2R5T8; hsa:7415; P55072; Q0V924; Q2TAI5; Q969G7; Q9UCD5"	"Alstrom syndrome; Clock-controlled autophagy in bone metabolism"	"Neddylation; E3 ubiquitin ligases ubiquitinate target proteins; ABC-family proteins mediated transport; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Defective CFTR causes cystic fibrosis; KEAP1-NFE2L2 pathway; Aggrephagy; Neutrophil degranulation; Attachment and Entry; Attachment and Entry; Ovarian tumor domain proteases; Josephin domain DUBs; Protein methylation; RHOH GTPase cycle; HSF1 activation; Translesion Synthesis by POLH; N-glycan trimming in the ER and Calnexin/Calreticulin cycle"	"20"	"0"	"2300.5"	"1953.1"	"2101.3"	"1954.0"	"1978.2"	"1929.2"	"2439.6"	"3024.3"	"2871.0"	"4222.2"	"5129.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EE3"	"Nucleoporin SEH1 OS=Homo sapiens OX=9606 GN=SEH1L PE=1 SV=3"	"0.000"	""	"32"	"8"	"19"	"8"	"360"	"39.6"	"8.09"	"3797.77"	"48.70"	"6"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;other biological processes"	"other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00400"	"81929"	"ENSG00000085415"	"SEH1L"	"A8K5B1; hsa:81929; Q8NFU6; Q96EE3; Q96MH3; Q9C069"	""	"Amino acids regulate mTORC1"	"1"	"0"	"433.2"	"310.0"	"468.8"	"411.0"	"410.7"	"396.8"	"546.7"	"903.5"	"835.5"	"2075.7"	"3254.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H6T3"	"RNA polymerase II-associated protein 3 OS=Homo sapiens OX=9606 GN=RPAP3 PE=1 SV=2"	"0.000"	""	"25"	"14"	"28"	"14"	"665"	"75.7"	"6.84"	"5889.18"	"48.55"	"12"	"12"	"other biological processes"	"cytosol;other cell component"	""	"Pf00515, Pf13176, Pf13181, Pf13877"	"79657"	"ENSG00000005175"	"RPAP3"	"B4DRW9; hsa:79657; Q6PHR5; Q9H6T3"	""	""	"0"	"0"	"432.7"	"337.2"	"469.3"	"426.4"	"411.2"	"424.3"	"556.3"	"2295.9"	"2397.2"	"6891.4"	"8020.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P53582"	"Methionine aminopeptidase 1 OS=Homo sapiens OX=9606 GN=METAP1 PE=1 SV=2"	"0.000"	""	"38"	"10"	"15"	"10"	"386"	"43.2"	"7.17"	"1861.50"	"48.43"	"4"	"10"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00557, Pf15801"	"23173"	"ENSG00000164024"	"METAP1"	"B4E2E6; hsa:23173; P53582"	""	"Inactivation, recovery and regulation of the phototransduction cascade"	"1"	"0"	"613.6"	"459.6"	"554.5"	"540.4"	"509.1"	"469.4"	"844.8"	"1888.3"	"1800.4"	"3922.5"	"4649.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14571"	"Inositol 1,4,5-trisphosphate receptor type 2 OS=Homo sapiens OX=9606 GN=ITPR2 PE=1 SV=2"	"0.000"	""	"6"	"13"	"27"	"11"	"2701"	"307.9"	"6.43"	"4915.28"	"48.36"	"11"	"12"	"stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf00520, Pf01365, Pf02815, Pf08454, Pf08709"	"3709"	"ENSG00000123104"	"ITPR2"	"hsa:3709; O94773; Q14571"	"Alzheimer's disease and miRNA effects; Myometrial relaxation and contraction pathways; Vitamin D-sensitive calcium signaling in depression; Thyroid hormones production and peripheral downstream signaling effects; Alzheimer's disease; GDNF signaling; Calcium regulation in cardiac cells"	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Ion homeostasis; Role of phospholipids in phagocytosis; FCERI mediated Ca+2 mobilization; FCGR3A-mediated IL10 synthesis; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Ca2+ pathway; VEGFR2 mediated cell proliferation; Elevation of cytosolic Ca2+ levels; PLC beta mediated events; DAG and IP3 signaling; CLEC7A (Dectin-1) induces NFAT activation; Effects of PIP2 hydrolysis"	"21"	"2"	"664.2"	"527.9"	"657.1"	"625.7"	"608.2"	"664.0"	"807.9"	"1180.1"	"1159.4"	"2419.9"	"3675.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6NVY1"	"3-hydroxyisobutyryl-CoA hydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=HIBCH PE=1 SV=2"	"0.000"	""	"36"	"14"	"31"	"14"	"386"	"43.5"	"8.19"	"6251.62"	"48.24"	"12"	"13"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf16113"	"26275"	"ENSG00000198130"	"HIBCH"	"D3DPI4; hsa:26275; Q53GA8; Q53GF2; Q53RF7; Q53TC6; Q6NVY1; Q92931; Q9BS94"	"Amino acid metabolism"	"Branched-chain amino acid catabolism"	"2"	"0"	"399.2"	"296.2"	"458.3"	"433.3"	"432.2"	"448.6"	"565.1"	"3868.6"	"4191.9"	"12602.7"	"17499.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86VP6"	"Cullin-associated NEDD8-dissociated protein 1 OS=Homo sapiens OX=9606 GN=CAND1 PE=1 SV=2"	"0.000"	""	"14"	"12"	"25"	"12"	"1230"	"136.3"	"5.78"	"4750.95"	"48.16"	"11"	"12"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf08623"	"55832"	"ENSG00000111530"	"CAND1"	"B2RAU3; hsa:55832; O94918; Q6PIY4; Q86VP6; Q8NDJ4; Q96JZ9; Q96T19; Q9BTC4; Q9H0G2; Q9P0H7; Q9UF85"	"Endoderm differentiation"	"Neutrophil degranulation; Neddylation; Iron uptake and transport"	"4"	"0"	"428.0"	"312.5"	"443.9"	"435.9"	"389.3"	"408.6"	"538.0"	"2276.0"	"2606.3"	"6406.4"	"8963.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NR30"	"Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5"	"0.000"	""	"15"	"9"	"22"	"8"	"783"	"87.3"	"9.28"	"5901.38"	"47.95"	"9"	"8"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf08152"	"9188"	"ENSG00000165732"	"DDX21"	"B2RDL0; hsa:9188; Q13436; Q5VX41; Q68D35; Q9NR30"	"10q11.21q11.23 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression; Major pathway of rRNA processing in the nucleolus and cytosol"	"3"	"0"	"846.0"	"581.2"	"838.7"	"773.4"	"737.0"	"789.1"	"997.5"	"2023.3"	"2020.1"	"4032.0"	"5756.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BW27"	"Nuclear pore complex protein Nup85 OS=Homo sapiens OX=9606 GN=NUP85 PE=1 SV=1"	"0.000"	""	"18"	"10"	"20"	"10"	"656"	"75.0"	"5.55"	"3212.12"	"47.87"	"8"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf07575"	"79902"	"ENSG00000125450"	"NUP85"	"B4DMQ3; B4DPW1; hsa:79902; Q8NDI4; Q9BW27; Q9H9U1"	""	"HCMV Late Events; HCMV Early Events; Transcriptional regulation by small RNAs; SARS-CoV-2 activates/modulates innate and adaptive immune responses; tRNA processing in the nucleus; Separation of Sister Chromatids; Viral Messenger RNA Synthesis; SUMOylation of DNA damage response and repair proteins; Rev-mediated nuclear export of HIV RNA; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Postmitotic nuclear pore complex (NPC) reformation"	"35"	"0"	"538.2"	"450.5"	"551.2"	"549.8"	"430.4"	"481.6"	"690.8"	"1197.7"	"1160.3"	"2388.2"	"3238.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00159"	"Unconventional myosin-Ic OS=Homo sapiens OX=9606 GN=MYO1C PE=1 SV=4"	"0.000"	""	"12"	"11"	"24"	"10"	"1063"	"121.6"	"9.41"	"4875.26"	"47.47"	"9"	"11"	"cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00063, Pf00612, Pf06017"	"4641"	"ENSG00000197879"	"MYO1C"	"hsa:4641; O00159; Q4LE56; Q6NVJ7; Q86Y95"	"VEGFA-VEGFR2 signaling; Insulin signaling; 10q11.21q11.23 copy number variation syndrome"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Translocation of SLC2A4 (GLUT4) to the plasma membrane"	"8"	"1"	"360.9"	"293.3"	"375.3"	"355.5"	"376.9"	"432.8"	"601.1"	"1753.4"	"1911.0"	"3182.6"	"3558.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UEY8"	"Gamma-adducin OS=Homo sapiens OX=9606 GN=ADD3 PE=1 SV=1"	"0.000"	""	"18"	"13"	"27"	"12"	"706"	"79.1"	"6.32"	"4480.32"	"47.45"	"10"	"12"	"cell organization and biogenesis"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00596"	"120"	"ENSG00000148700"	"ADD3"	"D3DRA8; hsa:120; O43243; Q5VU09; Q92773; Q9UEY7; Q9UEY8"	""	"Miscellaneous transport and binding events; RHOD GTPase cycle; RHOF GTPase cycle"	"3"	"0"	"960.6"	"772.2"	"831.9"	"893.7"	"807.8"	"804.5"	"1010.0"	"2552.3"	"2542.1"	"4347.7"	"4879.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75475"	"PC4 and SFRS1-interacting protein OS=Homo sapiens OX=9606 GN=PSIP1 PE=1 SV=1"	"0.000"	""	"28"	"12"	"29"	"12"	"530"	"60.1"	"9.13"	"5590.12"	"47.26"	"10"	"11"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00855, Pf11467"	"11168"	"ENSG00000164985"	"PSIP1"	"D3DRI9; hsa:11168; O00256; O75475; O95368; Q6P391; Q86YB9; Q9NZI3; Q9UER6"	"MECP2 and associated Rett syndrome"	"Formation of WDR5-containing histone-modifying complexes; Vpr-mediated nuclear import of PICs; 2-LTR circle formation; Integration of viral DNA into host genomic DNA; Autointegration results in viral DNA circles; APOBEC3G mediated resistance to HIV-1 infection"	"8"	"0"	"1248.9"	"1003.0"	"1219.1"	"1075.2"	"1153.2"	"1168.5"	"1510.9"	"2471.7"	"2332.5"	"3755.6"	"4033.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08708"	"40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2"	"0.000"	""	"56"	"6"	"12"	"6"	"135"	"15.5"	"9.85"	"807.89"	"46.98"	"2"	"6"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00833"	"6218"	"ENSG00000182774; ENSG00000278229"	"RPS17"	"B2R4U4; hsa:6218; P08708; P0CW22"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"540.8"	"540.9"	"583.2"	"522.9"	"552.4"	"570.7"	"760.6"	"901.8"	"873.7"	"1581.1"	"1936.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P29692"	"Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5"	"0.000"	""	"41"	"13"	"26"	"11"	"281"	"31.1"	"5.01"	"5257.02"	"46.70"	"12"	"11"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00736, Pf10587"	"1936"	"ENSG00000104529; ENSG00000273594"	"EEF1D"	"B4DDU4; D3DWK3; E9PBQ9; hsa:1936; P29692; Q4VBZ6; Q969J1; Q96I38"	"Translation factors"	"Eukaryotic Translation Elongation"	"2"	"2"	"1176.1"	"919.9"	"1058.6"	"1057.6"	"969.7"	"979.1"	"1313.5"	"2132.7"	"1996.1"	"4852.8"	"6830.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P33991"	"DNA replication licensing factor MCM4 OS=Homo sapiens OX=9606 GN=MCM4 PE=1 SV=5"	"0.000"	""	"16"	"11"	"19"	"11"	"863"	"96.5"	"6.74"	"2485.06"	"46.57"	"7"	"11"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf14551, Pf17207, Pf17855"	"4173"	"ENSG00000104738"	"MCM4"	"hsa:4173; P33991; Q8NEH1; Q99658"	"Cell cycle; Gastric cancer network 1; Retinoblastoma gene in cancer; Ciliary landscape; G1 to S cell cycle control; DNA replication"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"12"	"0"	"687.9"	"477.1"	"706.7"	"644.1"	"573.4"	"567.8"	"742.3"	"1152.7"	"1190.7"	"3136.7"	"6840.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14498"	"RNA-binding protein 39 OS=Homo sapiens OX=9606 GN=RBM39 PE=1 SV=2"	"0.000"	""	"20"	"9"	"19"	"8"	"530"	"59.3"	"10.10"	"1922.08"	"46.34"	"6"	"9"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00076, Pf15519"	"9584"	"ENSG00000131051"	"RBM39"	"A2RRD3; A5D8W2; B0BLV3; E1P5S0; E1P5S1; hsa:9584; Q14498; Q14499"	"VEGFA-VEGFR2 signaling; mRNA processing"	"mRNA Splicing - Major Pathway"	"3"	"1"	"885.2"	"652.9"	"793.6"	"767.3"	"661.8"	"661.8"	"905.6"	"1339.8"	"1314.5"	"2715.2"	"3458.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15428"	"Splicing factor 3A subunit 2 OS=Homo sapiens OX=9606 GN=SF3A2 PE=1 SV=2"	"0.000"	""	"15"	"7"	"21"	"7"	"464"	"49.2"	"9.64"	"4961.25"	"46.23"	"5"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf12874, Pf16835"	"8175"	"ENSG00000104897"	"SF3A2"	"B2RBU1; D6W605; hsa:8175; O75245; Q15428"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"619.2"	"568.9"	"546.9"	"526.8"	"565.7"	"597.6"	"722.0"	"1796.5"	"1765.1"	"5176.1"	"8002.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P38919"	"Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4"	"0.000"	""	"28"	"10"	"22"	"10"	"411"	"46.8"	"6.73"	"4785.78"	"46.03"	"8"	"9"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"9775"	"ENSG00000141543"	"EIF4A3"	"hsa:9775; P38919; Q15033; Q6IBQ2; Q96A18"	"TAR syndrome"	"mRNA Splicing - Major Pathway; Regulation of expression of SLITs and ROBOs; Deadenylation of mRNA; ISG15 antiviral mechanism; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	"9"	"0"	"717.3"	"584.7"	"724.6"	"619.0"	"570.9"	"657.8"	"852.7"	"1327.8"	"1421.2"	"3929.5"	"6871.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51659"	"Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3"	"0.000"	""	"21"	"12"	"23"	"12"	"736"	"79.6"	"8.84"	"3793.22"	"45.98"	"9"	"12"	"other metabolic processes;developmental processes"	"cytosol;other cytoplasmic organelle"	"other molecular function"	"Pf00106, Pf01575, Pf02036"	"3295"	"ENSG00000133835"	"HSD17B4"	"B4DNV1; B4DVS5; E9PB82; F5HE57; hsa:3295; P51659"	"Androgen receptor network in prostate cancer; Steroid biosynthesis; Disorders of bile acid synthesis and biliary transport; Primary ovarian insufficiency"	"TYSND1 cleaves peroxisomal proteins; Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol; alpha-linolenic acid (ALA) metabolism; Beta-oxidation of pristanoyl-CoA; Beta-oxidation of very long chain fatty acids"	"10"	"0"	"413.9"	"287.4"	"390.9"	"366.5"	"385.4"	"403.9"	"509.4"	"1113.8"	"1164.5"	"3017.5"	"4880.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00267"	"Transcription elongation factor SPT5 OS=Homo sapiens OX=9606 GN=SUPT5H PE=1 SV=1"	"0.000"	""	"17"	"13"	"21"	"13"	"1087"	"120.9"	"5.06"	"3835.94"	"45.92"	"9"	"11"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00467, Pf03439, Pf11942"	"6829"	"ENSG00000196235"	"SUPT5H"	"hsa:6829; O00267; O43279; Q59G52; Q99639"	"Initiation of transcription and translation elongation at the HIV-1 LTR; mRNA processing"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE"	"20"	"0"	"1849.4"	"1538.6"	"1718.2"	"1631.6"	"1554.9"	"1567.0"	"2145.0"	"2882.8"	"2669.5"	"4650.6"	"5968.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVA2"	"Septin-11 OS=Homo sapiens OX=9606 GN=SEPTIN11 PE=1 SV=3"	"0.000"	""	"33"	"12"	"27"	"9"	"429"	"49.4"	"6.81"	"4594.96"	"45.87"	"10"	"11"	"cell cycle OR cell proliferation"	"cytoskeleton;other cell component"	"other molecular function"	"Pf00735"	"55752"	"ENSG00000138758"	"SEPTIN11"	"B7Z7Z6; E9KL32; hsa:55752; Q4W5G1; Q7L4N1; Q96SP1; Q9NVA2; Q9UFY9"	"22q11.2 copy number variation syndrome"	""	"1"	"2"	"519.7"	"377.7"	"508.4"	"455.1"	"478.1"	"509.3"	"670.4"	"1970.2"	"1806.5"	"3988.6"	"5543.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15717"	"ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2"	"0.000"	""	"33"	"9"	"24"	"9"	"326"	"36.1"	"9.17"	"4548.39"	"45.77"	"9"	"9"	"cell organization and biogenesis;transport;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"1994"	"ENSG00000066044"	"ELAVL1"	"B4DVB8; hsa:1994; Q15717; Q53XN6; Q9BTT1"	"AMP-activated protein kinase signaling; Endoderm differentiation; Pre-implantation embryo; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Gastrin signaling pathway; IL-18 signaling pathway; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; 1p36 copy number variation syndrome"	"HuR (ELAVL1) binds and stabilizes mRNA"	"10"	"0"	"900.9"	"702.5"	"948.8"	"837.2"	"777.2"	"716.0"	"1038.0"	"1505.5"	"1475.5"	"3089.3"	"4932.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q2TAY7"	"WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2"	"0.000"	""	"27"	"11"	"24"	"11"	"513"	"57.5"	"7.18"	"4246.38"	"45.74"	"10"	"11"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf00400, Pf17814"	"55234"	"ENSG00000122692"	"SMU1"	"B4E3L0; hsa:55234; Q2TAY7; Q9BU59; Q9HA96; Q9NVD1"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"745.4"	"616.2"	"651.8"	"665.2"	"623.8"	"674.0"	"873.2"	"1487.4"	"1337.6"	"2862.5"	"4041.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46940"	"Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1"	"0.000"	""	"11"	"15"	"26"	"13"	"1657"	"189.1"	"6.48"	"5261.28"	"45.68"	"14"	"12"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00307, Pf00612, Pf00616, Pf03836"	"8826"	"ENSG00000140575"	"IQGAP1"	"A7MBM3; hsa:8826; P46940"	"VEGFA-VEGFR2 signaling; Ebola virus infection in host; Ciliary landscape; EGF/EGFR signaling pathway; Regulation of actin cytoskeleton; G13 signaling pathway"	"Signaling by BRAF and RAF1 fusions; RHOC GTPase cycle; RHOA GTPase cycle; Neutrophil degranulation; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RHO GTPases activate IQGAPs; RAC2 GTPase cycle; RHOV GTPase cycle; RHOU GTPase cycle; Nephrin family interactions; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants"	"25"	"2"	"451.5"	"276.8"	"514.9"	"455.2"	"429.1"	"497.2"	"616.9"	"2063.7"	"2146.5"	"5655.9"	"5840.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15293"	"Reticulocalbin-1 OS=Homo sapiens OX=9606 GN=RCN1 PE=1 SV=1"	"0.000"	""	"36"	"10"	"19"	"10"	"331"	"38.9"	"5.00"	"3582.81"	"45.43"	"7"	"10"	"developmental processes"	"ER/Golgi"	"other molecular function"	"Pf13202"	"5954"	"ENSG00000049449"	"RCN1"	"B7Z1M1; D3DR00; hsa:5954; Q15293"	"VEGFA-VEGFR2 signaling"	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation"	"3"	"0"	"1300.1"	"1070.1"	"1129.5"	"1245.9"	"1078.6"	"1128.5"	"1507.8"	"1726.6"	"1667.0"	"2316.1"	"2784.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23921"	"Ribonucleoside-diphosphate reductase large subunit OS=Homo sapiens OX=9606 GN=RRM1 PE=1 SV=1"	"0.000"	""	"16"	"10"	"21"	"10"	"792"	"90.0"	"7.15"	"3823.47"	"45.32"	"8"	"9"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf00317, Pf02867, Pf03477"	"6240"	"ENSG00000167325"	"RRM1"	"hsa:6240; P23921; Q9UNN2"	"Fluoropyrimidine activity; Retinoblastoma gene in cancer; Pyrimidine metabolism"	"Interconversion of nucleotide di- and triphosphates"	"4"	"0"	"316.8"	"198.4"	"277.6"	"275.6"	"267.2"	"291.3"	"391.2"	"1380.5"	"1441.3"	"3642.1"	"5569.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NQ29"	"Putative RNA-binding protein Luc7-like 1 OS=Homo sapiens OX=9606 GN=LUC7L PE=1 SV=1"	"0.000"	""	"19"	"7"	"22"	"3"	"371"	"43.7"	"9.92"	"3352.36"	"45.27"	"6"	"7"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03194"	"55692"	"ENSG00000007392"	"LUC7L"	"B8ZZ13; hsa:55692; Q96S32; Q9NPH4; Q9NQ29"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"234.1"	"204.6"	"221.7"	"219.3"	"202.9"	"236.8"	"291.4"	"676.8"	"672.6"	"1764.0"	"2363.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30876"	"DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1"	"0.000"	""	"12"	"14"	"28"	"14"	"1174"	"133.8"	"6.87"	"6076.29"	"45.26"	"14"	"12"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00562, Pf04560, Pf04561, Pf04563, Pf04565, Pf04566, Pf04567"	"5431"	"ENSG00000047315"	"POLR2B"	"A8K1A8; hsa:5431; P30876; Q8IZ61"	"Pyrimidine metabolism; Eukaryotic transcription initiation"	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"43"	"0"	"1833.0"	"1431.6"	"1776.7"	"1670.1"	"1558.1"	"1556.2"	"2229.9"	"2770.3"	"2597.4"	"4590.5"	"6337.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WUA2"	"Peptidyl-prolyl cis-trans isomerase-like 4 OS=Homo sapiens OX=9606 GN=PPIL4 PE=1 SV=1"	"0.000"	""	"24"	"12"	"22"	"12"	"492"	"57.2"	"5.92"	"3219.27"	"45.21"	"9"	"12"	"protein metabolism;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf00076, Pf00160"	"85313"	"ENSG00000131013"	"PPIL4"	"B2RD34; hsa:85313; Q7Z3Q5; Q8WUA2"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"457.0"	"387.2"	"609.5"	"496.9"	"513.0"	"515.7"	"631.9"	"2172.1"	"2190.0"	"6314.1"	"8329.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H0D6"	"5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1"	"0.000"	""	"17"	"12"	"25"	"12"	"950"	"108.5"	"7.47"	"5950.39"	"45.20"	"11"	"10"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03159, Pf17846"	"22803"	"ENSG00000088930"	"XRN2"	"hsa:22803; Q3L8N4; Q6KGZ9; Q9BQL1; Q9H0D6; Q9NTW0; Q9NXS6; Q9UL53"	"mRNA processing"	"Major pathway of rRNA processing in the nucleolus and cytosol; Association of TriC/CCT with target proteins during biosynthesis"	"3"	"0"	"1184.8"	"911.8"	"1119.3"	"1109.1"	"1011.2"	"965.6"	"1403.7"	"2131.1"	"1982.8"	"3819.1"	"5366.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75937"	"DnaJ homolog subfamily C member 8 OS=Homo sapiens OX=9606 GN=DNAJC8 PE=1 SV=2"	"0.000"	""	"43"	"11"	"20"	"11"	"253"	"29.8"	"9.06"	"3167.45"	"45.10"	"8"	"10"	""	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00226"	"22826"	"ENSG00000126698; ENSG00000285317"	"DNAJC8"	"B4DUU4; D3DPM0; hsa:22826; O75937; Q6IBA4; Q8N4Z5; Q9P051; Q9P067"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"887.0"	"621.7"	"815.2"	"741.4"	"804.1"	"845.9"	"1168.2"	"3022.9"	"2872.5"	"4792.0"	"5430.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62736"	"Actin, aortic smooth muscle OS=Homo sapiens OX=9606 GN=ACTA2 PE=1 SV=1"	"0.000"	""	"20"	"8"	"29"	"1"	"377"	"42.0"	"5.39"	"5380.75"	"44.74"	"8"	"7"	"developmental processes;other biological processes"	"extracellular matrix;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00022"	"59"	"ENSG00000107796"	"ACTA2"	"B2R8A4; hsa:59; P03996; P04108; P62736; Q6FI19"	"Myometrial relaxation and contraction pathways; Striated muscle contraction pathway; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; 22q11.2 copy number variation syndrome; IL-18 signaling pathway; Regucalcin in proximal tubule epithelial kidney cells; Angiotensin II receptor type 1 pathway; Pleural mesothelioma; CCL18 signaling pathway; Urotensin-II-mediated signaling pathway; Markers of kidney cell lineage; Comprehensive IL-17A signaling; IL-26 signaling pathways; A network map of Macrophage-stimulating protein (MSP) signaling"	"Smooth Muscle Contraction; NOTCH4 Intracellular Domain Regulates Transcription"	"16"	"0"	"177.0"	"173.9"	"187.9"	"165.6"	"146.8"	"166.4"	"196.7"	"414.6"	"405.2"	"918.7"	"1512.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60610"	"Protein diaphanous homolog 1 OS=Homo sapiens OX=9606 GN=DIAPH1 PE=1 SV=2"	"0.000"	""	"11"	"13"	"28"	"13"	"1272"	"141.3"	"5.41"	"5492.32"	"44.68"	"13"	"11"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf02181, Pf06346, Pf06367, Pf06371"	"1729"	"ENSG00000131504"	"DIAPH1"	"A6NF18; B7ZKW2; E9PEZ2; hsa:1729; O60610; Q17RN4; Q59FH8; Q9UC76"	"Microtubule cytoskeleton regulation; AGE/RAGE pathway; Focal adhesion; Type 2 papillary renal cell carcinoma; Regulation of actin cytoskeleton; G13 signaling pathway"	"RHOC GTPase cycle; RHOA GTPase cycle; RHO GTPases Activate Formins; RHOB GTPase cycle; RHOD GTPase cycle; RHOF GTPase cycle; Neutrophil degranulation; ERBB2 Regulates Cell Motility"	"14"	"0"	"1255.4"	"960.6"	"1114.1"	"1131.1"	"958.2"	"1077.8"	"1386.7"	"2000.1"	"1811.9"	"3523.0"	"4554.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43583"	"Density-regulated protein OS=Homo sapiens OX=9606 GN=DENR PE=1 SV=2"	"0.000"	""	"43"	"6"	"18"	"6"	"198"	"22.1"	"5.30"	"2720.31"	"44.64"	"5"	"6"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	""	"nucleic acid binding activity"	"Pf01253"	"8562"	"ENSG00000139726"	"DENR"	"hsa:8562; O43583; Q9H3U6; Q9UKZ0"	""	""	"0"	"0"	"199.1"	"168.4"	"233.3"	"191.7"	"198.8"	"193.6"	"283.4"	"1674.2"	"1645.0"	"3569.3"	"4053.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P84243"	"Histone H3.3 OS=Homo sapiens OX=9606 GN=H3-3A PE=1 SV=2"	"0.000"	""	"55"	"9"	"24"	"1"	"136"	"15.3"	"11.27"	"4154.19"	"44.61"	"7"	"9"	"cell organization and biogenesis;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125"	"3020; 3021"	"ENSG00000132475; ENSG00000163041"	"H3-3A; H3-3B"	"hsa:3020; hsa:3021; P06351; P33155; P84243; Q5VV55; Q5VV56; Q66I33; Q9V3W4"	"Gastric cancer network 1; Histone modifications; Tumor suppressor activity of SMARCB1; Ciliary landscape; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; DYRK1A involvement regarding cell proliferation in brain development; 4p16.3 copy number variation; 5q35 copy number variation"	"Estrogen-dependent gene expression; Senescence-Associated Secretory Phenotype (SASP); RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Amyloid fiber formation; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Transcriptional regulation by small RNAs; B-WICH complex positively regulates rRNA expression; Formation of the beta-catenin:TCF transactivating complex; Oxidative Stress Induced Senescence; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Pre-NOTCH Transcription and Translation; Factors involved in megakaryocyte development and platelet production; RNA Polymerase I Promoter Escape; Meiotic recombination; Inhibition of DNA recombination at telomere; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Condensation of Prophase Chromosomes; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis"	"34"	"0"	"5.7"	"0.0"	"2.9"	"3.5"	"7.2"	"6.8"	"7.4"	"7.6"	"15.1"	"41.9"	"67.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35240"	"Merlin OS=Homo sapiens OX=9606 GN=NF2 PE=1 SV=1"	"0.000"	""	"24"	"15"	"31"	"14"	"595"	"69.6"	"6.47"	"5965.92"	"44.57"	"15"	"12"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity"	"Pf00373, Pf00769, Pf09379, Pf09380, Pf20492"	"4771"	"ENSG00000186575"	"NF2"	"hsa:4771; O95683; P35240; Q8WUJ2; Q969N0; Q969Q3; Q96T30; Q96T31; Q96T32; Q96T33; Q9BTW3; Q9UNG9; Q9UNH3; Q9UNH4"	"Ectoderm differentiation; Ectoderm differentiation; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-YAP signaling; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; 3q29 copy number variation syndrome; Pleural mesothelioma"	"Regulation of actin dynamics for phagocytic cup formation; RHO GTPases activate PAKs"	"10"	"1"	"1383.3"	"997.5"	"1349.4"	"1199.8"	"1183.5"	"1204.1"	"1575.9"	"4301.7"	"4009.1"	"5895.6"	"5611.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42167"	"Lamina-associated polypeptide 2, isoforms beta/gamma OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2"	"0.000"	""	"30"	"11"	"20"	"4"	"454"	"50.6"	"9.38"	"3789.50"	"44.52"	"8"	"10"	""	"other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03020, Pf08198"	"7112"	"ENSG00000120802"	"TMPO"	"A2T926; hsa:7112; P42167; Q14861"	"Envelope proteins and their potential roles in EDMD physiopathology; Overlap between signal transduction pathways contributing to LMNA laminopathies"	"RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOJ GTPase cycle; RHOG GTPase cycle; RHOD GTPase cycle; RHOF GTPase cycle"	"12"	"0"	"477.6"	"414.7"	"481.5"	"426.8"	"438.6"	"467.7"	"509.3"	"872.8"	"833.7"	"1434.3"	"1699.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N1F7"	"Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2"	"0.000"	""	"15"	"13"	"29"	"13"	"819"	"93.4"	"5.72"	"5512.42"	"44.42"	"12"	"11"	"cell organization and biogenesis;other metabolic processes;transport;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus"	"other molecular function"	"Pf04097"	"9688"	"ENSG00000102900"	"NUP93"	"B3KPQ8; hsa:9688; Q14705; Q8N1F7"	""	"SUMOylation of DNA replication proteins; Regulation of HSF1-mediated heat shock response; HCMV Early Events; Transport of Mature mRNA derived from an Intron-Containing Transcript; HCMV Late Events; Transcriptional regulation by small RNAs; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Postmitotic nuclear pore complex (NPC) reformation"	"29"	"0"	"1232.4"	"806.5"	"1093.2"	"1064.8"	"913.2"	"992.9"	"1292.6"	"2108.4"	"2103.5"	"4254.9"	"5566.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WWY3"	"U4/U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2"	"0.000"	""	"28"	"11"	"22"	"11"	"499"	"55.4"	"5.78"	"3747.71"	"44.40"	"9"	"11"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01798, Pf09785"	"26121"	"ENSG00000105618; ENSG00000274144; ENSG00000274651; ENSG00000274894; ENSG00000275117; ENSG00000275885; ENSG00000276421; ENSG00000277154; ENSG00000277707; ENSG00000277953"	"PRPF31"	"E7ESA8; F1T0A4; F1T0A5; hsa:26121; Q17RB4; Q8N7F9; Q8WWY3; Q9H271; Q9Y439"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"1441.1"	"1109.8"	"1169.1"	"1129.4"	"1138.5"	"1095.5"	"1520.3"	"1891.9"	"1852.5"	"3236.1"	"4164.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96BP3"	"Peptidylprolyl isomerase domain and WD repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=PPWD1 PE=1 SV=1"	"0.000"	""	"22"	"10"	"18"	"9"	"646"	"73.5"	"7.15"	"3057.53"	"44.22"	"6"	"9"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00160, Pf00400"	"23398"	"ENSG00000113593"	"PPWD1"	"B4DWR9; hsa:23398; Q15002; Q7KZ89; Q96BP3"	""	"mRNA Splicing - Major Pathway"	"1"	"1"	"452.3"	"379.1"	"434.2"	"393.8"	"384.5"	"402.3"	"530.0"	"1380.0"	"1340.8"	"5339.3"	"7383.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6UN15"	"Pre-mRNA 3'-end-processing factor FIP1 OS=Homo sapiens OX=9606 GN=FIP1L1 PE=1 SV=1"	"0.000"	""	"21"	"8"	"22"	"8"	"594"	"66.5"	"5.59"	"4754.79"	"44.10"	"7"	"7"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	""	"Pf05182"	"81608"	"ENSG00000145216"	"FIP1L1"	"B4DIR3; G3XAD6; hsa:81608; Q0VGE0; Q499Y4; Q49AU3; Q6UN15; Q7Z608; Q8WVN3; Q96F80; Q9H077"	""	"Transport of Mature mRNA Derived from an Intronless Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs; Signaling by cytosolic PDGFRA and PDGFRB fusion proteins"	"6"	"0"	"964.2"	"820.2"	"734.2"	"781.0"	"693.7"	"760.1"	"976.7"	"1257.7"	"1180.2"	"2008.3"	"2807.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P24534"	"Elongation factor 1-beta OS=Homo sapiens OX=9606 GN=EEF1B2 PE=1 SV=3"	"0.000"	""	"57"	"12"	"27"	"10"	"225"	"24.7"	"4.67"	"5507.68"	"44.05"	"11"	"8"	"protein metabolism;other metabolic processes"	"cytosol;other cell component"	"enzyme regulator activity;nucleic acid binding activity"	"Pf00736, Pf10587"	"1933"	"ENSG00000114942; ENSG00000283391"	"EEF1B2"	"A8K795; hsa:1933; P24534; Q6IBH9"	"Translation factors"	"Eukaryotic Translation Elongation"	"2"	"0"	"2226.4"	"1933.0"	"1936.5"	"1886.0"	"1768.4"	"1771.8"	"2293.9"	"3550.9"	"3431.5"	"7575.6"	"10456.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49736"	"DNA replication licensing factor MCM2 OS=Homo sapiens OX=9606 GN=MCM2 PE=1 SV=4"	"0.000"	""	"15"	"9"	"19"	"9"	"904"	"101.8"	"5.52"	"3710.43"	"44.02"	"7"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf12619, Pf14551, Pf17207, Pf17855"	"4171"	"ENSG00000073111"	"MCM2"	"hsa:4171; P49736; Q14577; Q15023; Q8N2V1; Q969W7; Q96AE1; Q9BRM7"	"Cell cycle; Ciliary landscape; G1 to S cell cycle control; DNA replication; 1p36 copy number variation syndrome"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"11"	"0"	"269.2"	"196.5"	"300.1"	"288.0"	"269.0"	"314.6"	"459.9"	"704.1"	"804.4"	"1467.4"	"2593.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96ST2"	"Protein IWS1 homolog OS=Homo sapiens OX=9606 GN=IWS1 PE=1 SV=2"	"0.000"	""	"14"	"10"	"22"	"10"	"819"	"91.9"	"4.69"	"4625.54"	"44.02"	"9"	"8"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus"	""	"Pf08711"	"55677"	"ENSG00000163166"	"IWS1"	"hsa:55677; Q2TB65; Q6P157; Q8N3E8; Q96MI7; Q96ST2; Q9NV97; Q9NWH8"	""	"Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events"	"3"	"0"	"1147.5"	"967.4"	"1178.7"	"1080.6"	"1067.2"	"1042.1"	"1316.6"	"1660.8"	"1576.9"	"2433.4"	"3339.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95747"	"Serine/threonine-protein kinase OSR1 OS=Homo sapiens OX=9606 GN=OXSR1 PE=1 SV=1"	"0.000"	""	"27"	"9"	"18"	"8"	"527"	"58.0"	"6.43"	"3111.27"	"43.98"	"6"	"8"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf12202"	"9943"	"ENSG00000172939"	"OXSR1"	"hsa:9943; O95747; Q3LR53; Q7Z501; Q9UPQ1"	""	""	"0"	"2"	"109.3"	"78.1"	"141.6"	"134.3"	"121.8"	"129.7"	"164.4"	"740.7"	"835.7"	"2773.9"	"3980.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N7H5"	"RNA polymerase II-associated factor 1 homolog OS=Homo sapiens OX=9606 GN=PAF1 PE=1 SV=2"	"0.000"	""	"30"	"14"	"27"	"14"	"531"	"59.9"	"4.63"	"5596.59"	"43.93"	"14"	"11"	"cell-cell signaling;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf03985"	"54623"	"ENSG00000006712"	"PAF1"	"hsa:54623; M0QX35; O75239; Q8N7H5; Q9H166; Q9NUU9"	"Endoderm differentiation"	"E3 ubiquitin ligases ubiquitinate target proteins; Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events"	"5"	"0"	"1760.3"	"1436.2"	"1573.2"	"1550.2"	"1449.1"	"1429.3"	"1967.1"	"2381.8"	"2225.4"	"3698.1"	"5018.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P60709"	"Actin, cytoplasmic 1 OS=Homo sapiens OX=9606 GN=ACTB PE=1 SV=1"	"0.000"	""	"27"	"9"	"24"	"2"	"375"	"41.7"	"5.48"	"4694.71"	"43.73"	"8"	"8"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00022"	"60"	"ENSG00000075624"	"ACTB"	"hsa:60; P02570; P60709; P70514; P99021; Q11211; Q64316; Q75MN2; Q96B34; Q96HG5"	"Arrhythmogenic right ventricular cardiomyopathy; Pathogenic Escherichia coli infection; Common pathways underlying drug addiction; Myometrial relaxation and contraction pathways; Focal adhesion; Fas ligand pathway and stress induction of heat shock proteins; Ebola virus infection in host; Acute viral myocarditis; Thermogenesis; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Overlap between signal transduction pathways contributing to LMNA laminopathies; Pleural mesothelioma; Regulation of actin cytoskeleton; Network map of SARS-CoV-2 signaling pathway"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; UCH proteinases; Clathrin-mediated endocytosis; DNA Damage Recognition in GG-NER; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; Recycling pathway of L1; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; RHO GTPases Activate WASPs and WAVEs; RHO GTPases activate IQGAPs; RHO GTPases Activate Formins; RHOF GTPase cycle; B-WICH complex positively regulates rRNA expression; Signaling by BRAF and RAF1 fusions; EPHB-mediated forward signaling; VEGFA-VEGFR2 Pathway; Factors involved in megakaryocyte development and platelet production; EPH-ephrin mediated repulsion of cells; HATs acetylate histones; Interaction between L1 and Ankyrins; Prefoldin mediated transfer of substrate  to CCT/TriC; Signaling by RAF1 mutants; Adherens junctions interactions; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; Formation of annular gap junctions; Folding of actin by CCT/TriC; Cell-extracellular matrix interactions"	"47"	"9"	"1047.7"	"846.5"	"1169.6"	"983.6"	"893.1"	"863.2"	"1102.3"	"1785.0"	"1832.2"	"3505.0"	"5442.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15042"	"U2 snRNP-associated SURP motif-containing protein OS=Homo sapiens OX=9606 GN=U2SURP PE=1 SV=2"	"0.000"	""	"16"	"15"	"28"	"14"	"1029"	"118.2"	"8.47"	"5656.45"	"43.38"	"14"	"11"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf00076, Pf01805, Pf04818, Pf08312"	"23350"	"ENSG00000163714"	"U2SURP"	"A0PJ60; hsa:23350; O15042; Q0D2M1; Q2NKQ7; Q9BR70"	""	"mRNA Splicing - Major Pathway"	"1"	"1"	"1978.1"	"1562.4"	"1941.0"	"1939.9"	"1758.1"	"1772.0"	"2289.5"	"2891.1"	"2812.9"	"5722.8"	"7850.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60716"	"Catenin delta-1 OS=Homo sapiens OX=9606 GN=CTNND1 PE=1 SV=1"	"0.000"	""	"18"	"16"	"29"	"16"	"968"	"108.1"	"6.23"	"7210.70"	"43.28"	"16"	"12"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00514"	"1500"	"ENSG00000198561"	"CTNND1"	"A8K939; hsa:1500; O15088; O60713; O60714; O60715; O60716; O60935; Q6DHZ7; Q6RBX8; Q9UP71; Q9UP72; Q9UP73"	"VEGFA-VEGFR2 signaling; Wnt signaling pathway and pluripotency"	"VEGFR2 mediated vascular permeability; Adherens junctions interactions; InlA-mediated entry of Listeria monocytogenes into host cells; Regulation of CDH11 function; Regulation of CDH19 Expression and Function; CDH11 homotypic and heterotypic interactions"	"8"	"0"	"1541.0"	"1231.5"	"1402.4"	"1390.5"	"1245.6"	"1334.2"	"1681.6"	"2739.8"	"2793.9"	"5248.8"	"7056.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P38159"	"RNA-binding motif protein, X chromosome OS=Homo sapiens OX=9606 GN=RBMX PE=1 SV=3"	"0.000"	""	"27"	"9"	"26"	"3"	"391"	"42.3"	"10.05"	"5105.55"	"43.28"	"9"	"9"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08081"	"27316"	"ENSG00000147274"	"RBMX"	"B4E3U4; D3DWH0; E9PG86; hsa:27316; P38159; Q5JQ67; Q8N8Y7; Q969R3"	"mRNA processing"	"mRNA Splicing - Major Pathway; RND2 GTPase cycle; RND3 GTPase cycle; RND1 GTPase cycle; Processing of Capped Intron-Containing Pre-mRNA; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle"	"8"	"6"	"2447.6"	"2299.7"	"2405.0"	"2136.6"	"2139.8"	"2095.9"	"2748.8"	"3170.2"	"2878.2"	"4827.4"	"7658.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13247"	"Serine/arginine-rich splicing factor 6 OS=Homo sapiens OX=9606 GN=SRSF6 PE=1 SV=2"	"0.000"	""	"29"	"11"	"24"	"7"	"344"	"39.6"	"11.43"	"3620.45"	"43.27"	"9"	"10"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076"	"6431"	"ENSG00000124193"	"SRSF6"	"B7Z6J3; E1P5W6; hsa:6431; Q13244; Q13245; Q13247; Q96J06; Q9UJB8; Q9Y3N7"	"mRNA processing"	"RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing"	"7"	"4"	"2876.0"	"2290.3"	"2698.4"	"2568.0"	"2463.9"	"2185.0"	"3026.6"	"3582.0"	"3170.0"	"4821.5"	"7145.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15365"	"Poly(rC)-binding protein 1 OS=Homo sapiens OX=9606 GN=PCBP1 PE=1 SV=2"	"0.000"	""	"28"	"8"	"19"	"3"	"356"	"37.5"	"7.09"	"3857.46"	"43.13"	"6"	"8"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013"	"5093"	"ENSG00000169564"	"PCBP1"	"hsa:5093; Q13157; Q14975; Q15365"	"Ferroptosis"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"3"	"0"	"176.3"	"114.4"	"217.0"	"175.9"	"154.3"	"132.6"	"240.8"	"415.5"	"434.2"	"929.5"	"1290.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y490"	"Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3"	"0.000"	""	"7"	"14"	"22"	"14"	"2541"	"269.6"	"6.07"	"4272.63"	"43.07"	"10"	"11"	"cell adhesion;cell organization and biogenesis;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00373, Pf01608, Pf08913, Pf09141, Pf16511"	"7094"	"ENSG00000137076"	"TLN1"	"A6NMY0; hsa:7094; Q86YD0; Q9NZQ2; Q9UHH8; Q9UPX3; Q9Y490"	"Integrin-mediated cell adhesion; Primary focal segmental glomerulosclerosis (FSGS); Focal adhesion; TROP2 regulatory signaling"	"Platelet degranulation ; Signaling by BRAF and RAF1 fusions; XBP1(S) activates chaperone genes; SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion; Smooth Muscle Contraction; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; GRB2:SOS provides linkage to MAPK signaling for Integrins ; p130Cas linkage to MAPK signaling for integrins"	"18"	"0"	"1108.7"	"886.5"	"1029.9"	"969.5"	"909.3"	"974.6"	"1222.2"	"2239.2"	"1917.4"	"3876.2"	"7128.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12905"	"Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2"	"0.000"	""	"25"	"8"	"15"	"8"	"390"	"43.0"	"5.26"	"3413.32"	"43.07"	"6"	"7"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf07528"	"3608"	"ENSG00000143621"	"ILF2"	"A6NDB0; B2R8G7; hsa:3608; Q12905; Q5SR10; Q5SR11; Q7L7R3; Q9BWD4; Q9P1N0"	"B cell receptor signaling pathway"	"Neutrophil degranulation"	"2"	"0"	"1348.3"	"1200.6"	"1207.7"	"1080.7"	"1032.6"	"1156.8"	"1543.0"	"1937.5"	"1732.4"	"3040.3"	"5001.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EK5"	"KIF-binding protein OS=Homo sapiens OX=9606 GN=KIFBP PE=1 SV=1"	"0.000"	""	"21"	"11"	"21"	"11"	"621"	"71.8"	"5.49"	"4897.67"	"43.06"	"10"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes"	"cytoskeleton;mitochondrion"	"cytoskeletal activity"	"Pf12309"	"26128"	"ENSG00000198954"	"KIFBP"	"A8K5M8; hsa:26128; Q96EK5; Q9BR89; Q9ULE1; Q9Y428"	""	""	"0"	"0"	"298.7"	"212.1"	"461.3"	"323.2"	"351.0"	"469.5"	"856.7"	"4700.7"	"4877.6"	"6675.0"	"5041.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52292"	"Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1"	"0.000"	""	"26"	"11"	"22"	"11"	"529"	"57.8"	"5.40"	"4057.18"	"43.03"	"9"	"9"	"DNA metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00514, Pf01749, Pf16186"	"3838"	"ENSG00000182481"	"KPNA2"	"B9EJD6; hsa:3838; P52292; Q53YE3; Q6NVW7; Q9BRU5"	""	"ISG15 antiviral mechanism; NS1 Mediated Effects on Host Pathways; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Estrogen-dependent gene expression; SARS-CoV-1 activates/modulates innate immune responses; Sensing of DNA Double Strand Breaks; CaMK IV-mediated phosphorylation of CREB; CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde"	"8"	"0"	"907.2"	"698.1"	"882.9"	"797.4"	"747.7"	"802.2"	"1096.8"	"1941.3"	"1877.6"	"5196.4"	"7937.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75934"	"Pre-mRNA-splicing factor SPF27 OS=Homo sapiens OX=9606 GN=BCAS2 PE=1 SV=1"	"0.000"	""	"41"	"9"	"20"	"9"	"225"	"26.1"	"5.66"	"3817.42"	"42.89"	"8"	"9"	"RNA metabolism OR transcription;other metabolic processes"	"cytoskeleton;nucleus;other cell component"	""	"Pf05700"	"10286"	"ENSG00000116752"	"BCAS2"	"hsa:10286; O75934; Q6FGS0"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"267.8"	"197.9"	"283.8"	"258.6"	"246.5"	"253.8"	"397.1"	"1285.5"	"1329.2"	"4666.5"	"5906.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WYA6"	"Beta-catenin-like protein 1 OS=Homo sapiens OX=9606 GN=CTNNBL1 PE=1 SV=1"	"0.000"	""	"21"	"11"	"26"	"11"	"563"	"65.1"	"5.05"	"4757.09"	"42.88"	"10"	"11"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf08216"	"56259"	"ENSG00000132792"	"CTNNBL1"	"B4DE16; hsa:56259; Q0VAL9; Q0VAM0; Q53HI8; Q5JWZ2; Q5JWZ3; Q5JWZ7; Q5JWZ8; Q8N454; Q8NCL2; Q8TBD6; Q8WYA6; Q96KD2; Q9H7A5; Q9NQF9; Q9NTX0; Q9Y3M7"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"675.8"	"493.6"	"695.3"	"628.6"	"594.3"	"601.1"	"830.0"	"2120.1"	"2185.8"	"8701.9"	"11583.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15637"	"Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4"	"0.000"	""	"18"	"8"	"20"	"8"	"639"	"68.3"	"8.98"	"3570.27"	"42.82"	"6"	"8"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"translational apparatus;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf00098, Pf16275"	"7536"	"ENSG00000168066"	"SF1"	"B7Z1Q1; C9JJE2; hsa:7536; Q14818; Q14819; Q15637; Q15913; Q8IY00; Q92744; Q92745; Q969H7; Q9BW01; Q9UEI0"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"1383.6"	"1107.4"	"1461.1"	"1308.6"	"1345.1"	"1382.6"	"1684.7"	"2548.7"	"2525.1"	"4325.5"	"5465.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46777"	"60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3"	"0.000"	""	"27"	"10"	"26"	"10"	"297"	"34.3"	"9.72"	"6228.47"	"42.70"	"10"	"8"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf14204, Pf17144"	"6125"	"ENSG00000122406"	"RPL5"	"hsa:6125; P46777; Q32LZ3; Q53HH6; Q9H3F4"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"15"	"0"	"2152.5"	"1642.9"	"1759.0"	"1750.6"	"1754.4"	"1854.3"	"2508.8"	"3181.5"	"2875.6"	"5097.3"	"7359.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P53396"	"ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3"	"0.000"	""	"11"	"10"	"24"	"10"	"1101"	"120.8"	"7.33"	"4747.01"	"42.69"	"10"	"10"	"other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00285, Pf00549, Pf02629, Pf16114"	"47"	"ENSG00000131473"	"ACLY"	"B4DIM0; B4E3P0; hsa:47; P53396; Q13037; Q9BRL0"	"Sterol regulatory element-binding proteins (SREBP) signaling; TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Fatty acid biosynthesis; Amino acid metabolism; Lipid metabolism pathway; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer"	"Neutrophil degranulation; ChREBP activates metabolic gene expression; Fatty acyl-CoA biosynthesis"	"10"	"0"	"511.7"	"424.7"	"504.2"	"469.7"	"435.4"	"459.0"	"657.0"	"1028.0"	"1009.7"	"2751.5"	"4619.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P06576"	"ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3"	"0.000"	""	"18"	"8"	"21"	"8"	"529"	"56.5"	"5.40"	"4998.52"	"42.64"	"8"	"7"	"other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;mitochondrion;other cell component"	"signal transduction activity or receptor binding;transporter activity;other molecular function"	"Pf00006, Pf02874"	"506"	"ENSG00000110955"	"ATP5F1B"	"A8K4X0; hsa:506; P06576; Q14283"	"Electron transport chain: OXPHOS system in mitochondria; 7q11.23 copy number variation syndrome; Oxidative phosphorylation"	"Transcriptional activation of mitochondrial biogenesis; Mitochondrial protein import; Cristae formation; Formation of ATP by chemiosmotic coupling"	"7"	"0"	"433.2"	"334.5"	"469.5"	"408.9"	"375.4"	"397.7"	"546.6"	"1371.0"	"1313.1"	"4581.6"	"7141.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IX12"	"Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2"	"0.000"	""	"14"	"14"	"27"	"14"	"1150"	"132.7"	"5.76"	"4846.49"	"42.64"	"14"	"13"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02037, Pf14443, Pf14444, Pf19256, Pf19257"	"55749"	"ENSG00000060339"	"CCAR1"	"A0JLT7; A1L4P7; A8K9D4; B4DNP8; B4DRK8; hsa:55749; Q32NE3; Q5EBM3; Q5VUP6; Q6PIZ0; Q6X935; Q8IX12; Q9H8N4; Q9NVA7; Q9NVQ0; Q9NWM6"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"1020.4"	"695.0"	"923.6"	"873.3"	"822.9"	"799.8"	"1084.4"	"1538.1"	"1448.3"	"2854.7"	"5117.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NI27"	"THO complex subunit 2 OS=Homo sapiens OX=9606 GN=THOC2 PE=1 SV=2"	"0.000"	""	"9"	"10"	"23"	"10"	"1593"	"182.7"	"8.44"	"4235.69"	"42.60"	"7"	"10"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf11262, Pf11732, Pf16134"	"57187"	"ENSG00000125676"	"THOC2"	"A6NM50; hsa:57187; Q5JZ12; Q6IN92; Q8NI27; Q9H8I6"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"3"	"0"	"1285.9"	"952.7"	"1186.8"	"1149.2"	"1086.7"	"1142.9"	"1443.6"	"2180.9"	"2057.7"	"3485.3"	"4912.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49589"	"Cysteine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=CARS1 PE=1 SV=3"	"0.000"	""	"14"	"8"	"14"	"8"	"748"	"85.4"	"6.76"	"2457.51"	"42.49"	"4"	"8"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01406"	"833"	"ENSG00000110619; ENSG00000278191"	"CARS1"	"hsa:833; P49589; Q53XI8; Q5HYE4; Q9HD24; Q9HD25"	""	"Cytosolic tRNA aminoacylation; Signaling by ALK fusions and activated point mutants"	"2"	"0"	"208.0"	"177.1"	"204.4"	"201.7"	"214.4"	"208.2"	"251.8"	"871.7"	"1024.8"	"3294.9"	"7398.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42704"	"Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3"	"0.000"	""	"10"	"14"	"27"	"14"	"1394"	"157.8"	"6.13"	"5474.77"	"42.30"	"14"	"11"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"other membranes;cytoskeleton;mitochondrion;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf01535"	"10128"	"ENSG00000138095"	"LRPPRC"	"A0PJE3; A8K1V1; hsa:10128; P42704; Q53PC0; Q53QN7; Q6ZUD8; Q7Z7A6; Q96D84"	"Ciliary landscape"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"4"	"0"	"858.1"	"623.0"	"942.8"	"819.2"	"751.9"	"824.0"	"1089.0"	"2020.9"	"2033.9"	"5108.8"	"7756.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99615"	"DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2"	"0.000"	""	"29"	"16"	"33"	"16"	"494"	"56.4"	"6.96"	"6595.97"	"42.20"	"15"	"13"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00226, Pf13181, Pf13414, Pf13432"	"7266"	"ENSG00000168259"	"DNAJC7"	"hsa:7266; Q7Z784; Q99615"	"Constitutive androstane receptor pathway; Pregnane X receptor pathway; Nuclear receptors meta-pathway"	"Regulation of HSF1-mediated heat shock response"	"4"	"0"	"1279.2"	"1001.5"	"1315.7"	"1337.4"	"1265.6"	"1205.1"	"1670.6"	"3783.2"	"3754.2"	"9179.1"	"12555.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P26358"	"DNA (cytosine-5)-methyltransferase 1 OS=Homo sapiens OX=9606 GN=DNMT1 PE=1 SV=2"	"0.000"	""	"10"	"11"	"21"	"11"	"1616"	"183.1"	"7.75"	"3316.49"	"42.13"	"9"	"11"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00145, Pf01426, Pf02008, Pf06464, Pf12047"	"1786"	"ENSG00000130816"	"DNMT1"	"A0AV63; B7ZLW6; hsa:1786; P26358; Q9UHG5; Q9ULA2; Q9UMZ6"	"Trans-sulfuration pathway; One-carbon metabolism; Retinoblastoma gene in cancer; Hematopoietic stem cell gene regulation by GABP alpha/beta complex; MTHFR deficiency"	"SUMOylation of DNA methylation proteins; NoRC negatively regulates rRNA expression; PRC2 methylates histones and DNA; Defective pyroptosis; DNA methylation"	"10"	"0"	"1000.7"	"787.6"	"1012.5"	"1014.6"	"957.2"	"1004.1"	"1302.9"	"1643.7"	"1515.7"	"2133.7"	"2664.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3I0"	"RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1"	"0.000"	""	"23"	"12"	"27"	"12"	"505"	"55.2"	"7.23"	"4077.08"	"41.95"	"12"	"12"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01139"	"51493"	"ENSG00000100220"	"RTCB"	"B2R6A8; hsa:51493; Q6IAI0; Q9BWL4; Q9NTH1; Q9P037; Q9P0J3; Q9Y3I0"	"Unfolded protein response"	"tRNA processing in the nucleus"	"2"	"0"	"1506.2"	"1350.8"	"1648.7"	"1388.1"	"1434.8"	"1466.1"	"1836.1"	"2847.0"	"2965.9"	"4885.7"	"6206.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P67809"	"Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3"	"0.000"	""	"37"	"8"	"18"	"6"	"324"	"35.9"	"9.88"	"3124.46"	"41.79"	"5"	"7"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00313"	"4904"	"ENSG00000065978"	"YBX1"	"hsa:4904; P16990; P16991; P67809; Q14972; Q15325; Q5FVF0"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; MECP2 and associated Rett syndrome; mRNA processing; Sudden infant death syndrome (SIDS) susceptibility pathways"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Interferon gamma signaling; Noncanonical activation of NOTCH3"	"10"	"2"	"731.5"	"557.1"	"620.2"	"619.2"	"640.2"	"666.2"	"807.8"	"978.9"	"866.6"	"1376.8"	"1956.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96AG4"	"Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1"	"0.000"	""	"30"	"8"	"17"	"8"	"307"	"34.9"	"9.57"	"2607.85"	"41.75"	"5"	"8"	""	"other membranes;mitochondrion;ER/Golgi;nucleus;other cell component"	""	"Pf13855"	"55379"	"ENSG00000108829"	"LRRC59"	"B2RE83; D3DTX8; hsa:55379; Q96AG4; Q9P189"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"1128.3"	"1022.6"	"1064.1"	"957.0"	"950.4"	"1019.9"	"1380.3"	"2315.2"	"2278.8"	"4712.3"	"6062.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23381"	"Tryptophan--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=WARS1 PE=1 SV=2"	"0.000"	""	"25"	"8"	"13"	"8"	"471"	"53.1"	"6.23"	"979.42"	"41.57"	"3"	"8"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00458, Pf00579"	"7453"	"ENSG00000140105"	"WARS1"	"A6NGN1; A6NID3; hsa:7453; P23381; P78535; Q502Y0; Q53XB6; Q9UDI5; Q9UDL3"	"Photodynamic therapy-induced unfolded protein response; Amino acid metabolism"	"Cytosolic tRNA aminoacylation"	"3"	"0"	"140.6"	"84.8"	"356.7"	"147.3"	"159.2"	"145.3"	"183.9"	"794.1"	"810.1"	"3277.7"	"5864.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61158"	"Actin-related protein 3 OS=Homo sapiens OX=9606 GN=ACTR3 PE=1 SV=3"	"0.000"	""	"28"	"9"	"19"	"9"	"418"	"47.3"	"5.88"	"3445.96"	"41.28"	"8"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00022"	"10096"	"ENSG00000115091"	"ACTR3"	"hsa:10096; P32391; P61158; Q53QM2"	"Physico-chemical features and toxicity-associated pathways"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Clathrin-mediated endocytosis; EPHB-mediated forward signaling"	"6"	"0"	"477.7"	"381.8"	"438.4"	"394.5"	"421.0"	"428.7"	"615.2"	"1729.7"	"1740.5"	"3829.6"	"5343.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q02790"	"Peptidyl-prolyl cis-trans isomerase FKBP4 OS=Homo sapiens OX=9606 GN=FKBP4 PE=1 SV=3"	"0.000"	""	"25"	"9"	"16"	"9"	"459"	"51.8"	"5.43"	"2944.92"	"41.23"	"5"	"9"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00254, Pf00515"	"2288"	"ENSG00000004478"	"FKBP4"	"D3DUQ1; hsa:2288; Q02790; Q9UCP1; Q9UCV7"	"Androgen receptor signaling pathway"	"Estrogen-dependent gene expression; Potential therapeutics for SARS; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Attenuation phase"	"6"	"0"	"152.0"	"105.3"	"171.9"	"141.3"	"146.9"	"138.7"	"200.4"	"394.5"	"358.3"	"1929.5"	"5609.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N684"	"Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1"	"0.000"	""	"19"	"9"	"20"	"9"	"471"	"52.0"	"8.00"	"4512.20"	"41.03"	"9"	"8"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"79869"	"ENSG00000149532"	"CPSF7"	"B3KU04; C9K0Q4; hsa:79869; Q7Z3H9; Q8N684; Q9H025; Q9H9V1"	""	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs; RHOBTB1 GTPase cycle"	"5"	"0"	"1075.6"	"841.1"	"967.2"	"920.8"	"875.8"	"901.0"	"1206.8"	"2287.8"	"1921.2"	"4240.5"	"5954.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52209"	"6-phosphogluconate dehydrogenase, decarboxylating OS=Homo sapiens OX=9606 GN=PGD PE=1 SV=3"	"0.000"	""	"27"	"11"	"17"	"11"	"483"	"53.1"	"7.23"	"2648.68"	"40.91"	"6"	"11"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf00393, Pf03446"	"5226"	"ENSG00000142657"	"PGD"	"A8K2Y9; B4DQJ8; hsa:5226; P52209; Q9BWD8"	"Pentose phosphate metabolism; Nuclear receptors meta-pathway; NRF2 pathway; VEGFA-VEGFR2 signaling; Metabolic reprogramming in colon cancer"	"NFE2L2 regulates pentose phosphate pathway genes; Pentose phosphate pathway"	"7"	"0"	"778.9"	"503.8"	"749.5"	"716.1"	"637.6"	"626.1"	"878.6"	"2054.7"	"2173.7"	"7892.2"	"12276.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P1J9"	"Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1"	"0.000"	""	"26"	"12"	"23"	"12"	"531"	"60.5"	"9.61"	"4332.23"	"40.85"	"11"	"12"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf05179, Pf16050"	"79577"	"ENSG00000134371"	"CDC73"	"A6NLZ8; B2RBR2; hsa:79577; Q6P1J9; Q6PK51; Q96A07; Q9H245; Q9H5L7"	"Endoderm differentiation"	"Hedgehog 'on' state; E3 ubiquitin ligases ubiquitinate target proteins; Formation of the beta-catenin:TCF transactivating complex; Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events"	"7"	"0"	"1509.0"	"1272.7"	"1501.1"	"1363.5"	"1373.3"	"1417.9"	"1817.7"	"2346.1"	"2252.1"	"3923.4"	"4849.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94826"	"Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1"	"0.000"	""	"17"	"10"	"22"	"10"	"608"	"67.4"	"7.12"	"4154.36"	"40.75"	"9"	"9"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00515, Pf13181"	"9868"	"ENSG00000154174"	"TOMM70"	"D3DN48; hsa:9868; O94826"	"Mitochondrial immune response to SARS-CoV-2; SARS-CoV-2 B.1.1.7 variant antagonises innate immune activation; SARS-CoV-2 mitochondrial chronic oxidative stress and endothelial dysfunction"	"Ub-specific processing proteases; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Mitochondrial protein import; DDX58/IFIH1-mediated induction of interferon-alpha/beta; SARS-CoV-1 activates/modulates innate immune responses; PINK1-PRKN Mediated Mitophagy"	"9"	"0"	"551.5"	"441.8"	"560.7"	"590.9"	"540.4"	"542.0"	"692.7"	"2208.1"	"2461.6"	"5898.3"	"7697.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q04917"	"14-3-3 protein eta OS=Homo sapiens OX=9606 GN=YWHAH PE=1 SV=4"	"0.000"	""	"33"	"7"	"20"	"4"	"246"	"28.2"	"4.84"	"2997.89"	"40.58"	"5"	"7"	"other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00244"	"7533"	"ENSG00000128245"	"YWHAH"	"hsa:7533; Q04917"	"Cell cycle; Myometrial relaxation and contraction pathways; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"TP53 Regulates Metabolic Genes; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RHO GTPases activate PKNs; Translocation of SLC2A4 (GLUT4) to the plasma membrane; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Activation of BAD and translocation to mitochondria"	"11"	"0"	"512.4"	"468.2"	"442.2"	"441.8"	"387.8"	"471.3"	"596.2"	"946.8"	"850.4"	"1634.2"	"2242.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P26641"	"Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3"	"0.000"	""	"25"	"13"	"31"	"13"	"437"	"50.1"	"6.67"	"5506.19"	"40.46"	"13"	"11"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity"	"Pf00043, Pf00647, Pf02798"	"1937"	"ENSG00000254772"	"EEF1G"	"B4DTG2; hsa:1937; P26641; Q6PJ62; Q6PK31; Q96CU2; Q9P196"	"Translation factors"	"Signaling by ALK fusions and activated point mutants; Eukaryotic Translation Elongation"	"3"	"0"	"1970.7"	"1563.3"	"1877.8"	"1756.6"	"1748.0"	"1694.8"	"2276.2"	"3714.3"	"3751.2"	"9362.2"	"11731.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13647"	"Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3"	"0.000"	""	"17"	"12"	"24"	"8"	"590"	"62.3"	"7.74"	"3803.94"	"40.42"	"10"	"12"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;other cell component"	"bone, tooth or skin structural activity;cytoskeletal activity;other molecular function"	"Pf00038, Pf16208"	"3852"	"ENSG00000186081"	"KRT5"	"hsa:3852; P13647; Q6PI71; Q6UBJ0; Q8TA91"	""	"Formation of the cornified envelope; Type I hemidesmosome assembly"	"3"	"0"	"192.5"	"379.7"	"761.8"	"398.7"	"430.3"	"236.7"	"303.8"	"985.5"	"1082.2"	"1114.4"	"1608.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P18754"	"Regulator of chromosome condensation OS=Homo sapiens OX=9606 GN=RCC1 PE=1 SV=1"	"0.000"	""	"26"	"11"	"20"	"11"	"421"	"44.9"	"7.52"	"4084.80"	"40.41"	"9"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00415"	"1104"	"ENSG00000180198"	"RCC1"	"hsa:1104; P18754; Q16269; Q6NT97"	"22q11.2 copy number variation syndrome"	"Rev-mediated nuclear export of HIV RNA; Nuclear import of Rev protein; Postmitotic nuclear pore complex (NPC) reformation"	"4"	"0"	"1201.2"	"878.8"	"1183.6"	"1100.1"	"1058.8"	"1097.4"	"1518.0"	"2138.1"	"2057.4"	"3883.7"	"4222.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61201"	"COP9 signalosome complex subunit 2 OS=Homo sapiens OX=9606 GN=COPS2 PE=1 SV=1"	"0.000"	""	"20"	"8"	"18"	"8"	"443"	"51.6"	"5.53"	"3300.81"	"40.40"	"6"	"8"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01399"	"9318"	"ENSG00000166200"	"COPS2"	"hsa:9318; O88950; P61201; Q15647; Q6FGP4; Q9BY54; Q9R249; Q9UNI2; Q9UNQ5"	"Ciliary landscape"	"Cargo recognition for clathrin-mediated endocytosis; Neddylation; Formation of TC-NER Pre-Incision Complex; RHOBTB1 GTPase cycle; DNA Damage Recognition in GG-NER"	"6"	"0"	"215.4"	"162.0"	"223.7"	"225.2"	"227.0"	"290.4"	"448.1"	"1360.9"	"1421.1"	"4136.9"	"7745.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q05519"	"Serine/arginine-rich splicing factor 11 OS=Homo sapiens OX=9606 GN=SRSF11 PE=1 SV=1"	"0.000"	""	"15"	"8"	"17"	"8"	"484"	"53.5"	"10.52"	"3427.70"	"40.21"	"7"	"8"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00076"	"9295"	"ENSG00000116754"	"SRSF11"	"hsa:9295; Q05519; Q5T758; Q8IWE6"	""	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript"	"5"	"0"	"331.5"	"248.4"	"342.5"	"319.3"	"289.2"	"279.5"	"388.0"	"874.4"	"1007.5"	"3463.0"	"6266.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13263"	"Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5"	"0.000"	""	"11"	"9"	"17"	"9"	"835"	"88.5"	"5.77"	"3124.01"	"39.74"	"6"	"9"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00628, Pf00643, Pf14634"	"10155"	"ENSG00000130726"	"TRIM28"	"hsa:10155; O00677; Q13263; Q7Z632; Q93040; Q96IM1"	"Corticotropin-releasing hormone signaling pathway; Mesodermal commitment pathway; ATM signaling in development and disease"	"Generic Transcription Pathway; HCMV Early Events; SUMOylation of transcription cofactors"	"6"	"0"	"685.9"	"548.9"	"715.6"	"647.2"	"569.9"	"600.2"	"795.9"	"1390.8"	"1368.8"	"4443.2"	"8609.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55084"	"Trifunctional enzyme subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=HADHB PE=1 SV=3"	"0.000"	""	"25"	"13"	"23"	"12"	"474"	"51.3"	"9.41"	"5572.20"	"39.72"	"12"	"10"	"other metabolic processes;other biological processes"	"other membranes;mitochondrion;ER/Golgi"	"nucleic acid binding activity;other molecular function"	"Pf00108, Pf02803"	"3032"	"ENSG00000138029"	"HADHB"	"B2RB16; B4E2W0; hsa:3032; O14969; P55084; Q53TA6; Q96C77; Q9H3F5; Q9T2V8"	"Fatty acid beta-oxidation; Valproic acid pathway; Female steroid hormones in cardiomyocyte energy metabolism; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Acyl chain remodeling of CL; mitochondrial fatty acid beta-oxidation of unsaturated fatty acids; Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA; Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of myristoyl-CoA to lauroyl-CoA; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA; Beta oxidation of palmitoyl-CoA to myristoyl-CoA"	"12"	"0"	"896.1"	"745.6"	"885.4"	"798.6"	"785.1"	"792.1"	"1029.1"	"1566.0"	"1598.5"	"3794.6"	"6375.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08621"	"U1 small nuclear ribonucleoprotein 70 kDa OS=Homo sapiens OX=9606 GN=SNRNP70 PE=1 SV=2"	"0.000"	""	"31"	"11"	"21"	"11"	"437"	"51.5"	"9.94"	"4118.75"	"39.67"	"8"	"10"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf12220"	"6625"	"ENSG00000104852"	"SNRNP70"	"B3KUA3; hsa:6625; P08621; P78493; P78494; Q15364; Q15686; Q15687; Q15689; Q99377; Q9UE45; Q9UE46; Q9UE47; Q9UE48; Q9UFQ6"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"1913.0"	"1395.0"	"1656.8"	"1580.4"	"1446.9"	"1465.9"	"1953.0"	"2440.8"	"2029.4"	"2986.1"	"4729.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P34897"	"Serine hydroxymethyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=SHMT2 PE=1 SV=3"	"0.000"	""	"27"	"12"	"22"	"12"	"504"	"56.0"	"8.53"	"3940.48"	"39.57"	"10"	"11"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00464"	"6472"	"ENSG00000182199"	"SHMT2"	"B7Z9F1; E7EQ19; E7EU43; hsa:6472; O00740; P34897; Q8N1A5"	"Glycine metabolism; Vitamin B12 metabolism; Folate metabolism; One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Neuroinflammation and glutamatergic signaling; Metabolic Epileptic Disorders"	"RHOG GTPase cycle; Metabolism of folate and pterines"	"11"	"0"	"853.4"	"631.6"	"814.2"	"792.7"	"765.5"	"749.7"	"996.5"	"1444.0"	"1397.6"	"2914.5"	"4390.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43175"	"D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4"	"0.000"	""	"20"	"8"	"19"	"8"	"533"	"56.6"	"6.71"	"3382.77"	"39.52"	"6"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;developmental processes;other biological processes"	"cytosol"	"other molecular function"	"Pf00389, Pf02826, Pf19304"	"26227"	"ENSG00000092621"	"PHGDH"	"B2RD08; hsa:26227; O43175; Q5SZU3; Q9BQ01"	"Trans-sulfuration, one-carbon metabolism and related pathways; Clear cell renal cell carcinoma pathways; Neuroinflammation and glutamatergic signaling; Amino acid metabolism in triple-negative breast cancer cells"	"Serine biosynthesis"	"5"	"0"	"722.1"	"504.6"	"628.9"	"615.8"	"580.0"	"708.6"	"1016.7"	"1840.4"	"1879.8"	"4433.0"	"6887.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14966"	"Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2"	"0.000"	""	"8"	"12"	"24"	"12"	"1978"	"220.5"	"6.38"	"5478.53"	"39.45"	"11"	"11"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf12171"	"27332"	"ENSG00000075292"	"ZNF638"	"A0A096LPH6; B5MDV1; B7ZLD1; hsa:27332; Q14966; Q53R34; Q5XJ05; Q68DP3; Q6P2H2; Q7Z3T7; Q8NF92; Q8TCA1; Q9H2G1; Q9NP37"	""	"Transcriptional regulation of white adipocyte differentiation"	"1"	"0"	"1594.3"	"1365.8"	"1559.8"	"1465.5"	"1449.8"	"1516.8"	"1877.5"	"2818.7"	"2766.9"	"4595.1"	"5912.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30040"	"Endoplasmic reticulum resident protein 29 OS=Homo sapiens OX=9606 GN=ERP29 PE=1 SV=4"	"0.000"	""	"48"	"10"	"16"	"10"	"261"	"29.0"	"7.31"	"2026.11"	"39.13"	"6"	"10"	"protein metabolism;other metabolic processes;transport;other biological processes"	"ER/Golgi;other cell component"	"other molecular function"	"Pf07749, Pf07912"	"10961"	"ENSG00000089248"	"ERP29"	"C9J183; hsa:10961; P30040; Q3MJC3; Q6FHT4"	""	""	"0"	"0"	"203.0"	"163.6"	"238.3"	"236.5"	"219.5"	"221.4"	"285.1"	"1013.4"	"1099.7"	"4473.0"	"6013.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62081"	"40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1"	"0.000"	""	"53"	"8"	"15"	"8"	"194"	"22.1"	"10.10"	"2515.51"	"39.07"	"5"	"8"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf01251"	"6201"	"ENSG00000171863"	"RPS7"	"hsa:6201; P23821; P24818; P62081; Q57Z92; Q6IPH1"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery; rRNA modification in the nucleus and cytosol"	"20"	"0"	"501.9"	"421.5"	"501.7"	"470.3"	"446.0"	"475.1"	"632.6"	"1493.0"	"1579.2"	"4007.9"	"4405.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5BKZ1"	"DBIRD complex subunit ZNF326 OS=Homo sapiens OX=9606 GN=ZNF326 PE=1 SV=2"	"0.000"	""	"17"	"8"	"21"	"8"	"582"	"65.6"	"5.15"	"4709.99"	"39.02"	"8"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04988"	"284695"	"ENSG00000162664"	"ZNF326"	"A8MYX1; B4DLN0; B4E179; hsa:284695; Q5BKZ1; Q5VW93; Q5VW94; Q5VW96; Q5VW97; Q6NSA2; Q7Z638; Q7Z6C2"	""	""	"0"	"0"	"1740.1"	"1369.3"	"1774.1"	"1509.4"	"1548.8"	"1557.3"	"2143.9"	"2422.0"	"2118.4"	"3310.6"	"4687.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94906"	"Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1"	"0.000"	""	"17"	"14"	"24"	"14"	"941"	"106.9"	"8.25"	"4201.68"	"38.78"	"13"	"11"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf06424, Pf13181"	"24148"	"ENSG00000101161"	"PRPF6"	"B2RAR5; B3KMC6; hsa:24148; O94906; O95109; Q5VXS5; Q9H3Z1; Q9H4T9; Q9H4U8; Q9NTE6"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"3"	"0"	"1002.6"	"758.9"	"976.5"	"923.4"	"880.2"	"878.1"	"1186.6"	"2023.9"	"1984.3"	"4795.8"	"6717.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92804"	"TATA-binding protein-associated factor 2N OS=Homo sapiens OX=9606 GN=TAF15 PE=1 SV=1"	"0.000"	""	"16"	"7"	"16"	"4"	"592"	"61.8"	"8.02"	"2210.70"	"38.76"	"5"	"6"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00641"	"8148"	"ENSG00000270647; ENSG00000276833"	"TAF15"	"B2R837; hsa:8148; Q86X94; Q92751; Q92804"	"17q12 copy number variation syndrome"	"Regulation of TP53 Activity through Phosphorylation; RNA Polymerase II Pre-transcription Events; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation"	"10"	"0"	"707.5"	"419.7"	"682.5"	"532.4"	"560.1"	"524.8"	"757.2"	"1111.0"	"947.4"	"1683.6"	"2475.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H078"	"Caseinolytic peptidase B protein homolog OS=Homo sapiens OX=9606 GN=CLPB PE=1 SV=1"	"0.000"	""	"19"	"10"	"18"	"10"	"707"	"78.7"	"9.01"	"2785.96"	"38.57"	"8"	"10"	"stress response;signal transduction;other biological processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf07724, Pf10431, Pf12796, Pf13857"	"81570"	"ENSG00000162129"	"CLPB"	"B4DXJ7; B4DXP7; B4DXW4; E7EWN6; F8W7P6; hsa:81570; Q8ND11; Q9H078; Q9H8Y0"	""	""	"0"	"0"	"420.9"	"317.9"	"461.3"	"432.7"	"389.5"	"390.3"	"534.5"	"1179.3"	"1154.8"	"3325.0"	"5512.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11310"	"Medium-chain specific acyl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ACADM PE=1 SV=1"	"0.000"	""	"31"	"8"	"15"	"8"	"421"	"46.6"	"8.37"	"3000.15"	"38.47"	"7"	"8"	"other metabolic processes;stress response;developmental processes;other biological processes"	"other membranes;mitochondrion;other cell component"	"other molecular function"	"Pf00441, Pf02770, Pf02771"	"34"	"ENSG00000117054"	"ACADM"	"hsa:34; P11310; Q5T4U4; Q9NYF1"	"Fatty acid beta-oxidation; PPAR-alpha pathway; Nuclear receptors meta-pathway; Mitochondrial long chain fatty acid beta-oxidation; Amino acid metabolism; PPAR signaling pathway; Mitochondrial fatty acid oxidation disorders; Female steroid hormones in cardiomyocyte energy metabolism; Sudden infant death syndrome (SIDS) susceptibility pathways"	"PPARA activates gene expression; mitochondrial fatty acid beta-oxidation of unsaturated fatty acids; Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA"	"13"	"0"	"193.4"	"175.9"	"189.6"	"172.1"	"182.8"	"185.8"	"241.0"	"570.7"	"612.8"	"1658.7"	"2349.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBL3"	"Set1/Ash2 histone methyltransferase complex subunit ASH2 OS=Homo sapiens OX=9606 GN=ASH2L PE=1 SV=1"	"0.000"	""	"14"	"8"	"17"	"8"	"628"	"68.7"	"5.69"	"3620.18"	"38.45"	"7"	"8"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00622"	"9070"	"ENSG00000129691"	"ASH2L"	"A8K7C3; D3DSW9; hsa:9070; O60659; O60660; Q96B62; Q9UBL3"	"Kleefstra syndrome"	"Deactivation of the beta-catenin transactivating complex; Formation of the beta-catenin:TCF transactivating complex; Activation of anterior HOX genes in hindbrain development during early embryogenesis; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Formation of WDR5-containing histone-modifying complexes; PKMTs methylate histone lysines"	"7"	"0"	"355.3"	"298.0"	"319.6"	"295.3"	"297.5"	"317.5"	"416.2"	"1176.3"	"1193.6"	"3979.8"	"6562.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61981"	"14-3-3 protein gamma OS=Homo sapiens OX=9606 GN=YWHAG PE=1 SV=2"	"0.000"	""	"38"	"8"	"21"	"4"	"247"	"28.3"	"4.89"	"3583.26"	"38.42"	"6"	"8"	"transport;signal transduction;other biological processes"	"cytosol;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00244"	"7532"	"ENSG00000170027"	"YWHAG"	"hsa:7532; O70457; P35214; P61981; Q6FH52; Q9UDP2; Q9UN99"	"Cell cycle; Prolactin signaling pathway; Myometrial relaxation and contraction pathways; Disruption of postsynaptic signaling by CNV; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Regulation of localization of FOXO transcription factors; TP53 Regulates Metabolic Genes; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Activation of BAD and translocation to mitochondria"	"21"	"2"	"762.4"	"642.9"	"659.5"	"606.6"	"632.6"	"675.1"	"861.8"	"1020.3"	"1044.4"	"1400.0"	"1694.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12972"	"Nuclear inhibitor of protein phosphatase 1 OS=Homo sapiens OX=9606 GN=PPP1R8 PE=1 SV=2"	"0.000"	""	"21"	"6"	"15"	"6"	"351"	"38.5"	"7.37"	"3829.30"	"38.36"	"5"	"6"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00498"	"5511"	"ENSG00000117751"	"PPP1R8"	"hsa:5511; Q12972; Q5TEJ2; Q5TEJ4; Q5TIF2; Q6PKF6; Q9UBH1; Q9UBZ0"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"342.6"	"269.1"	"342.5"	"333.5"	"336.4"	"323.3"	"397.1"	"1020.7"	"1129.5"	"2708.8"	"3382.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60306"	"RNA helicase aquarius OS=Homo sapiens OX=9606 GN=AQR PE=1 SV=4"	"0.000"	""	"6"	"8"	"17"	"8"	"1485"	"171.2"	"6.37"	"3245.92"	"38.32"	"7"	"8"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf13086, Pf13087, Pf16399"	"9716"	"ENSG00000021776"	"AQR"	"A0JP17; A5YKK3; hsa:9716; O60306; Q2YDX9; Q6IRU8; Q6PIC8"	""	"mRNA Splicing - Major Pathway; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	"5"	"0"	"386.3"	"282.3"	"420.6"	"383.2"	"353.0"	"379.5"	"489.3"	"815.2"	"800.0"	"2568.9"	"4902.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55010"	"Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2"	"0.000"	""	"21"	"9"	"16"	"9"	"431"	"49.2"	"5.58"	"1965.93"	"38.32"	"4"	"9"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf01873, Pf02020"	"1983"	"ENSG00000100664"	"EIF5"	"hsa:1983; P55010; Q53XB3; Q9H5N2; Q9UG48"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"4"	"0"	"217.1"	"155.0"	"240.1"	"212.6"	"213.5"	"214.2"	"280.9"	"877.1"	"867.9"	"5750.8"	"10012.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q04637"	"Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4"	"0.000"	""	"6"	"8"	"22"	"7"	"1599"	"175.4"	"5.33"	"4183.43"	"38.24"	"8"	"8"	"protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02020, Pf02847, Pf02854"	"1981"	"ENSG00000114867"	"EIF4G1"	"D3DNT2; D3DNT4; D3DNT5; E9PFM1; G5E9S1; hsa:1981; O43177; O95066; Q04637; Q5HYG0; Q6ZN21; Q8N102"	"Translation factors; VEGFA-VEGFR2 signaling; Acute viral myocarditis; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Pleural mesothelioma"	"AUF1 (hnRNP D0) binds and destabilizes mRNA; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Deadenylation of mRNA; ISG15 antiviral mechanism; mTORC1-mediated signalling"	"18"	"1"	"659.1"	"533.0"	"639.0"	"635.0"	"623.6"	"635.7"	"792.9"	"1268.6"	"1257.4"	"3209.6"	"4137.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14566"	"DNA replication licensing factor MCM6 OS=Homo sapiens OX=9606 GN=MCM6 PE=1 SV=1"	"0.000"	""	"15"	"10"	"14"	"10"	"821"	"92.8"	"5.41"	"2167.00"	"37.81"	"5"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf14551, Pf17207, Pf17855, Pf18263"	"4175"	"ENSG00000076003"	"MCM6"	"B2R6H2; hsa:4175; Q13504; Q14566; Q99859"	"Cell cycle; Retinoblastoma gene in cancer; Ciliary landscape; G1 to S cell cycle control; DNA replication"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"11"	"0"	"523.8"	"370.8"	"548.0"	"509.4"	"468.2"	"468.4"	"624.8"	"920.9"	"866.2"	"2094.2"	"5063.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BT78"	"COP9 signalosome complex subunit 4 OS=Homo sapiens OX=9606 GN=COPS4 PE=1 SV=1"	"0.000"	""	"25"	"9"	"18"	"9"	"406"	"46.2"	"5.83"	"3208.85"	"37.81"	"6"	"9"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf01399, Pf18420"	"51138"	"ENSG00000138663"	"COPS4"	"B3KN88; B3KST5; hsa:51138; Q561W7; Q9BT78; Q9NW31; Q9Y677"	"Ciliary landscape"	"Cargo recognition for clathrin-mediated endocytosis; Neddylation; Formation of TC-NER Pre-Incision Complex; DNA Damage Recognition in GG-NER; RHOBTB1 GTPase cycle"	"6"	"0"	"228.7"	"180.2"	"219.4"	"228.9"	"233.4"	"253.3"	"386.7"	"1271.3"	"1258.6"	"5116.8"	"9761.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61604"	"10 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPE1 PE=1 SV=2"	"0.000"	""	"77"	"10"	"19"	"10"	"102"	"10.9"	"8.92"	"4692.87"	"37.75"	"9"	"8"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"mitochondrion"	"other molecular function"	"Pf00166"	"3336"	"ENSG00000115541"	"HSPE1"	"hsa:3336; O95421; P61604; Q04984; Q53X54; Q9UDH0"	""	"RHOG GTPase cycle"	"1"	"0"	"332.8"	"246.8"	"297.6"	"278.1"	"271.8"	"782.4"	"1452.2"	"4036.9"	"4147.9"	"8746.8"	"12190.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NTK5"	"Obg-like ATPase 1 OS=Homo sapiens OX=9606 GN=OLA1 PE=1 SV=2"	"0.000"	""	"31"	"10"	"18"	"10"	"396"	"44.7"	"7.81"	"2776.02"	"37.69"	"8"	"10"	"other metabolic processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cell component"	"translation activity;other molecular function"	"Pf01926, Pf06071"	"29789"	"ENSG00000138430"	"OLA1"	"D7EHM2; hsa:29789; Q5BJD7; Q8NCI8; Q96CU1; Q96SV2; Q9NTK5; Q9P1D3; Q9UNY9; Q9Y6G4"	""	"Platelet degranulation"	"1"	"0"	"665.5"	"535.6"	"614.9"	"614.0"	"570.6"	"664.5"	"864.3"	"1771.4"	"1735.3"	"4685.9"	"6451.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96T58"	"Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1"	"0.000"	""	"3"	"10"	"20"	"10"	"3664"	"402.0"	"7.64"	"4885.14"	"37.55"	"9"	"9"	"signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf07744"	"23013"	"ENSG00000065526"	"SPEN"	"hsa:23013; Q96T58; Q9H9A8; Q9NWH5; Q9UQ01; Q9Y556"	"Notch signaling pathway"	"RHOBTB1 GTPase cycle"	"2"	"0"	"1133.9"	"957.9"	"995.5"	"1027.0"	"940.3"	"1022.6"	"1269.2"	"1658.3"	"1499.4"	"2323.6"	"3069.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30419"	"Glycylpeptide N-tetradecanoyltransferase 1 OS=Homo sapiens OX=9606 GN=NMT1 PE=1 SV=2"	"0.000"	""	"24"	"10"	"20"	"7"	"496"	"56.8"	"7.80"	"3765.99"	"37.42"	"9"	"9"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf01233, Pf02799"	"4836"	"ENSG00000136448"	"NMT1"	"A8K7C1; hsa:4836; P30419; Q9UE09"	""	"Inactivation, recovery and regulation of the phototransduction cascade; Late Phase of HIV Life Cycle; Activation, myristolyation of BID and translocation to mitochondria"	"3"	"3"	"792.4"	"611.6"	"789.4"	"741.9"	"687.9"	"725.7"	"952.6"	"2531.6"	"2570.7"	"4894.0"	"4590.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P45973"	"Chromobox protein homolog 5 OS=Homo sapiens OX=9606 GN=CBX5 PE=1 SV=1"	"0.000"	""	"37"	"6"	"20"	"5"	"191"	"22.2"	"5.86"	"3871.20"	"37.37"	"6"	"5"	"cell organization and biogenesis;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00385, Pf01393"	"23468"	"ENSG00000094916"	"CBX5"	"B2R8T9; hsa:23468; P45973"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; 22q11.2 copy number variation syndrome"	"Factors involved in megakaryocyte development and platelet production; SUMOylation of chromatin organization proteins; Transcriptional Regulation by E2F6"	"5"	"1"	"367.2"	"315.6"	"389.0"	"343.3"	"322.8"	"341.8"	"449.3"	"1696.5"	"1711.7"	"4777.4"	"6651.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q01105"	"Protein SET OS=Homo sapiens OX=9606 GN=SET PE=1 SV=3"	"0.000"	""	"28"	"6"	"15"	"6"	"290"	"33.5"	"4.32"	"2848.23"	"37.25"	"5"	"6"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00956"	"6418"	"ENSG00000119335"	"SET"	"A5A5H4; A6NGV1; B4DUE2; hsa:6418; Q01105; Q15541; Q5VXV1; Q5VXV2; Q6FHZ5"	"Histone modifications; VEGFA-VEGFR2 signaling"	"HuR (ELAVL1) binds and stabilizes mRNA; Condensation of Prophase Chromosomes"	"4"	"0"	"610.5"	"764.4"	"535.8"	"534.9"	"526.3"	"587.7"	"842.9"	"1462.4"	"1176.0"	"2336.1"	"3372.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92922"	"SWI/SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3"	"0.000"	""	"12"	"10"	"20"	"8"	"1105"	"122.8"	"5.76"	"3637.44"	"37.25"	"9"	"9"	"cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00249, Pf04433, Pf16495, Pf16496, Pf16498"	"6599"	"ENSG00000173473"	"SMARCC1"	"hsa:6599; Q17RS0; Q6P172; Q8IWH2; Q92922"	"Androgen receptor network in prostate cancer; Tumor suppressor activity of SMARCB1; Thermogenesis; Kleefstra syndrome"	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; RMTs methylate histone arginines"	"6"	"2"	"683.2"	"538.8"	"708.6"	"656.0"	"606.0"	"637.1"	"856.0"	"1579.6"	"1511.8"	"3519.8"	"4719.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P27816"	"Microtubule-associated protein 4 OS=Homo sapiens OX=9606 GN=MAP4 PE=1 SV=3"	"0.000"	""	"13"	"11"	"21"	"11"	"1152"	"120.9"	"5.43"	"4752.68"	"37.21"	"10"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00418"	"4134"	"ENSG00000047849"	"MAP4"	"hsa:4134; P27816; Q13082; Q59FT2; Q68D74; Q6ZUW9; Q86V26; Q96A76; Q96NS9"	"Splicing factor NOVA regulated synaptic proteins; 2q37 copy number variation syndrome"	""	"2"	"0"	"1434.4"	"1179.4"	"1433.1"	"1409.7"	"1403.8"	"1389.3"	"1761.8"	"2072.6"	"1962.8"	"3093.3"	"4303.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60264"	"SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1"	"0.000"	""	"10"	"11"	"21"	"6"	"1052"	"121.8"	"8.09"	"3849.87"	"37.15"	"10"	"11"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf09110, Pf09111"	"8467"	"ENSG00000153147"	"SMARCA5"	"hsa:8467; O60264"	"10q11.21q11.23 copy number variation syndrome"	"Deposition of new CENPA-containing nucleosomes at the centromere; B-WICH complex positively regulates rRNA expression; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; NoRC negatively regulates rRNA expression"	"5"	"5"	"751.7"	"621.7"	"806.6"	"744.5"	"703.8"	"745.6"	"995.4"	"1875.6"	"1773.0"	"3347.6"	"4135.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P82979"	"SAP domain-containing ribonucleoprotein OS=Homo sapiens OX=9606 GN=SARNP PE=1 SV=3"	"0.000"	""	"31"	"9"	"23"	"9"	"210"	"23.7"	"6.42"	"5140.98"	"37.01"	"9"	"9"	"other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02037"	"84324"	"ENSG00000205323"	"SARNP"	"A8K393; hsa:84324; P82979; Q9P066"	""	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript"	"3"	"0"	"966.9"	"717.0"	"969.6"	"880.1"	"849.6"	"909.0"	"1165.7"	"3682.0"	"3768.0"	"5891.4"	"6084.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P84103"	"Serine/arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1"	"0.000"	""	"41"	"7"	"16"	"7"	"164"	"19.3"	"11.65"	"2034.02"	"36.99"	"4"	"7"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6428"	"ENSG00000112081"	"SRSF3"	"B4E241; hsa:6428; O08831; P23152; P84103; Q5R3K0"	"mRNA processing"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"6"	"0"	"1672.3"	"1443.3"	"1308.5"	"1211.1"	"1227.0"	"1140.1"	"1632.3"	"2183.8"	"1826.1"	"3307.1"	"5241.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14444"	"Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2"	"0.000"	""	"14"	"9"	"20"	"9"	"709"	"78.3"	"5.25"	"3498.00"	"36.95"	"8"	"8"	"cell organization and biogenesis;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf12287, Pf18293"	"4076"	"ENSG00000135387"	"CAPRIN1"	"A6NMY7; D3DR06; hsa:4076; Q14444; Q15074; Q6IMN4; Q6IMN7; Q9BV09"	""	""	"0"	"0"	"573.7"	"463.5"	"512.1"	"480.8"	"512.3"	"495.1"	"658.3"	"1380.4"	"1421.2"	"4489.3"	"6908.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96QC0"	"Serine/threonine-protein phosphatase 1 regulatory subunit 10 OS=Homo sapiens OX=9606 GN=PPP1R10 PE=1 SV=1"	"0.000"	""	"15"	"11"	"19"	"11"	"940"	"99.0"	"9.17"	"3800.68"	"36.57"	"9"	"10"	"transport;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00642, Pf08711"	"5514"	"ENSG00000204569; ENSG00000206489; ENSG00000227804; ENSG00000230995; ENSG00000231737; ENSG00000235291; ENSG00000238104"	"PPP1R10"	"hsa:5514; O00405; Q96QC0"	""	""	"0"	"0"	"1112.3"	"797.2"	"972.8"	"960.5"	"941.2"	"939.9"	"1223.7"	"1688.0"	"1634.3"	"2648.8"	"3425.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q05639"	"Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1"	"0.000"	""	"27"	"10"	"20"	"2"	"463"	"50.4"	"9.03"	"3390.96"	"36.54"	"8"	"8"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03143, Pf03144"	"1917"	"ENSG00000101210"	"EEF1A2"	"B5BUF3; E1P5J1; hsa:1917; P54266; Q05639; Q0VGC7"	"Translation factors"	"Eukaryotic Translation Elongation"	"2"	"0"	"45.1"	"34.2"	"38.7"	"43.8"	"37.5"	"44.1"	"60.2"	"91.3"	"84.4"	"136.9"	"163.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P00367"	"Glutamate dehydrogenase 1, mitochondrial OS=Homo sapiens OX=9606 GN=GLUD1 PE=1 SV=2"	"0.000"	""	"24"	"10"	"19"	"10"	"558"	"61.4"	"7.80"	"3073.83"	"36.43"	"9"	"10"	"other metabolic processes;other biological processes"	"mitochondrion;ER/Golgi;other cell component"	"other molecular function"	"Pf00208, Pf02812"	"2746"	"ENSG00000148672"	"GLUD1"	"B3KV55; B4DGN5; hsa:2746; P00367; Q5TBU3"	"VEGFA-VEGFR2 signaling; Amino acid metabolism; Metabolic reprogramming in colon cancer; 22q11.2 copy number variation syndrome; Amino acid metabolism pathway excerpt: histidine catabolism extension; 10q22q23 copy number variation"	"Transcriptional activation of mitochondrial biogenesis; Glutamate and glutamine metabolism"	"8"	"0"	"440.7"	"364.1"	"456.6"	"430.1"	"389.5"	"406.5"	"501.6"	"995.4"	"992.7"	"3102.8"	"5916.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92576"	"PHD finger protein 3 OS=Homo sapiens OX=9606 GN=PHF3 PE=1 SV=3"	"0.000"	""	"7"	"9"	"17"	"9"	"2039"	"229.3"	"6.96"	"3412.64"	"36.40"	"7"	"8"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00628, Pf07500, Pf07744"	"23469"	"ENSG00000118482"	"PHF3"	"A3KFI8; hsa:23469; Q14CR5; Q5CZI1; Q5T1T6; Q92576; Q9NQ16; Q9UI45"	""	""	"0"	"0"	"747.1"	"546.2"	"776.2"	"681.4"	"705.0"	"692.4"	"880.2"	"1310.7"	"1260.8"	"2450.4"	"3156.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q53GS9"	"U4/U6.U5 tri-snRNP-associated protein 2 OS=Homo sapiens OX=9606 GN=USP39 PE=1 SV=2"	"0.000"	""	"25"	"11"	"20"	"10"	"565"	"65.3"	"8.91"	"3281.56"	"36.35"	"10"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00443, Pf02148"	"10713"	"ENSG00000168883"	"USP39"	"A8K086; B3KM40; B4DHT4; D6W5L4; G5E9H0; hsa:10713; Q53GS9; Q6NX47; Q96RK9; Q9BV89; Q9H381; Q9P050; Q9Y310"	""	"mRNA Splicing - Major Pathway"	"1"	"1"	"690.7"	"560.0"	"608.4"	"633.1"	"604.1"	"588.4"	"803.3"	"1255.3"	"1168.3"	"2597.6"	"3284.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P29966"	"Myristoylated alanine-rich C-kinase substrate OS=Homo sapiens OX=9606 GN=MARCKS PE=1 SV=4"	"0.000"	""	"21"	"7"	"16"	"7"	"332"	"31.5"	"4.45"	"2930.27"	"36.22"	"6"	"7"	"cell organization and biogenesis;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02063"	"4082"	"ENSG00000277443"	"MARCKS"	"E1P560; hsa:4082; P29966; Q2LA83; Q5TDB7"	"Brain-derived neurotrophic factor (BDNF) signaling pathway"	"Acetylcholine regulates insulin secretion"	"2"	"0"	"319.5"	"240.7"	"315.4"	"285.7"	"292.3"	"290.9"	"371.8"	"2084.8"	"2223.4"	"5689.6"	"6663.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96CX2"	"BTB/POZ domain-containing protein KCTD12 OS=Homo sapiens OX=9606 GN=KCTD12 PE=1 SV=1"	"0.000"	""	"32"	"9"	"18"	"9"	"325"	"35.7"	"5.64"	"3521.43"	"36.06"	"9"	"9"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf02214"	"115207"	"ENSG00000178695"	"KCTD12"	"hsa:115207; Q96CX2"	""	""	"0"	"0"	"220.3"	"141.8"	"249.3"	"227.3"	"237.5"	"216.1"	"287.3"	"666.9"	"612.0"	"2133.4"	"3294.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23193"	"Transcription elongation factor A protein 1 OS=Homo sapiens OX=9606 GN=TCEA1 PE=1 SV=2"	"0.000"	""	"43"	"11"	"26"	"9"	"301"	"33.9"	"8.38"	"5359.00"	"35.97"	"11"	"8"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01096, Pf07500, Pf08711"	"6917"	"ENSG00000187735"	"TCEA1"	"A6NF25; A8K339; hsa:6917; P23193; Q15563; Q6FG87"	""	"Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	"15"	"2"	"647.6"	"478.9"	"656.3"	"629.3"	"580.5"	"635.4"	"840.4"	"2232.2"	"2253.0"	"5430.4"	"8166.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19388"	"DNA-directed RNA polymerases I, II, and III subunit RPABC1 OS=Homo sapiens OX=9606 GN=POLR2E PE=1 SV=4"	"0.000"	""	"45"	"8"	"15"	"8"	"210"	"24.5"	"5.95"	"2296.70"	"35.96"	"5"	"8"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01191, Pf03871"	"5434"	"ENSG00000099817"	"POLR2E"	"B2R6L4; D6W5Y1; hsa:5434; O43380; P19388; Q6PIH5; Q9BT06"	"Pyrimidine metabolism; Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"mRNA Splicing - Major Pathway; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Transcriptional regulation by small RNAs; B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; RNA Polymerase I Promoter Escape; Inhibition of DNA recombination at telomere; RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; Viral Messenger RNA Synthesis; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Transcription Termination; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM"	"57"	"0"	"411.0"	"337.6"	"437.3"	"412.8"	"412.5"	"403.9"	"556.4"	"1223.7"	"1247.5"	"3050.8"	"4096.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43172"	"U4/U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2"	"0.000"	""	"20"	"10"	"19"	"10"	"522"	"58.4"	"7.42"	"3958.64"	"35.79"	"9"	"9"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00400, Pf08799"	"9128"	"ENSG00000136875"	"PRPF4"	"hsa:9128; O43172; O43445; O43864; Q5T1M8; Q96DG2; Q96IK4"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"1021.9"	"725.6"	"885.9"	"877.3"	"862.8"	"787.3"	"1118.1"	"1646.3"	"1484.3"	"3089.4"	"4205.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60832"	"H/ACA ribonucleoprotein complex subunit DKC1 OS=Homo sapiens OX=9606 GN=DKC1 PE=1 SV=3"	"0.000"	""	"15"	"7"	"14"	"7"	"514"	"57.6"	"9.42"	"2886.58"	"35.76"	"5"	"7"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01472, Pf01509, Pf08068, Pf16198"	"1736"	"ENSG00000130826"	"DKC1"	"F5BSB3; hsa:1736; O43845; O60832; Q96G67; Q9Y505"	""	"rRNA modification in the nucleus and cytosol; Telomere Extension By Telomerase"	"2"	"0"	"466.1"	"381.9"	"465.6"	"432.5"	"418.5"	"406.3"	"517.5"	"926.4"	"881.4"	"2198.3"	"2911.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VUJ6"	"Leucine-rich repeat and calponin homology domain-containing protein 2 OS=Homo sapiens OX=9606 GN=LRCH2 PE=1 SV=2"	"0.000"	""	"15"	"7"	"13"	"7"	"765"	"84.5"	"6.55"	"2944.77"	"35.73"	"5"	"6"	""	""	""	"Pf00307, Pf13855"	"57631"	"ENSG00000130224"	"LRCH2"	"F5H2T1; hsa:57631; Q08AD5; Q5VUJ6; Q9HA88; Q9P233"	""	""	"0"	"0"	"313.9"	"250.0"	"337.6"	"474.5"	"307.7"	"360.2"	"448.2"	"842.9"	"788.0"	"1428.0"	"1578.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2D5"	"A-kinase anchor protein 2 OS=Homo sapiens OX=9606 GN=AKAP2 PE=1 SV=3"	"0.000"	""	"17"	"9"	"16"	"9"	"859"	"94.6"	"5.11"	"3239.40"	"35.63"	"8"	"8"	""	""	""	"Pf15304"	"445815"	""	"AKAP2"	"B1ALX9; B2RTU4; B3KQ00; B4DTZ2; B7ZW07; B9EJB5; Q9UG26; Q9Y2D5"	""	""	"0"	"0"	"667.5"	"646.9"	"663.4"	"677.5"	"641.0"	"655.7"	"827.1"	"1190.3"	"1184.3"	"2649.5"	"3262.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q29RF7"	"Sister chromatid cohesion protein PDS5 homolog A OS=Homo sapiens OX=9606 GN=PDS5A PE=1 SV=1"	"0.000"	""	"7"	"8"	"14"	"6"	"1337"	"150.7"	"7.91"	"2156.91"	"35.62"	"6"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	""	"Pf20168"	"23244"	"ENSG00000121892"	"PDS5A"	"hsa:23244; Q29RF7; Q2TTR5; Q68DF7; Q8N7J4; Q8NG14; Q9Y4D4"	"Cohesin complex - Cornelia de Lange syndrome; 10q22q23 copy number variation"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"6"	"1"	"489.4"	"383.3"	"456.9"	"448.5"	"441.1"	"467.2"	"579.5"	"1158.3"	"1133.0"	"2297.1"	"2800.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q05682"	"Caldesmon OS=Homo sapiens OX=9606 GN=CALD1 PE=1 SV=3"	"0.000"	""	"16"	"10"	"17"	"10"	"793"	"93.2"	"5.66"	"3051.12"	"35.58"	"8"	"9"	"cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton"	"cytoskeletal activity;other molecular function"	"Pf02029"	"800"	"ENSG00000122786"	"CALD1"	"A8K0X1; hsa:800; Q05682; Q13978; Q13979; Q14741; Q14742; Q9UD91"	"Myometrial relaxation and contraction pathways"	"Smooth Muscle Contraction"	"2"	"0"	"843.4"	"686.2"	"782.2"	"737.0"	"797.4"	"760.8"	"949.9"	"1810.4"	"1820.0"	"3878.5"	"4959.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P41250"	"Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3"	"0.000"	""	"16"	"9"	"14"	"8"	"739"	"83.1"	"7.03"	"1564.25"	"35.28"	"5"	"9"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"non-structural extracellular;cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00458, Pf00587, Pf03129"	"2617"	"ENSG00000106105"	"GARS1"	"A0A090N8G0; B3KQA2; B4DIA0; hsa:2617; P41250; Q969Y1"	""	"Cytosolic tRNA aminoacylation; Mitochondrial tRNA aminoacylation"	"2"	"0"	"276.1"	"213.6"	"338.6"	"300.5"	"302.8"	"289.5"	"353.6"	"688.8"	"654.8"	"2405.1"	"4948.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TCS8"	"Polyribonucleotide nucleotidyltransferase 1, mitochondrial OS=Homo sapiens OX=9606 GN=PNPT1 PE=1 SV=2"	"0.000"	""	"16"	"10"	"20"	"10"	"783"	"85.9"	"7.77"	"3190.72"	"35.17"	"9"	"9"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"other membranes;cytosol;mitochondrion;ER/Golgi;translational apparatus;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf01138, Pf03725, Pf03726"	"87178"	"ENSG00000138035"	"PNPT1"	"hsa:87178; Q53SU0; Q68CN1; Q7Z7D1; Q8IWX1; Q8TCS8; Q96T05; Q9BRU3; Q9BVX0"	"Pyrimidine metabolism; miRNA degrading enzymes"	""	"2"	"0"	"567.7"	"414.1"	"533.1"	"474.0"	"484.8"	"478.2"	"625.3"	"1252.4"	"1300.8"	"3102.9"	"4163.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62753"	"40S ribosomal protein S6 OS=Homo sapiens OX=9606 GN=RPS6 PE=1 SV=1"	"0.000"	""	"31"	"10"	"20"	"10"	"249"	"28.7"	"10.84"	"4332.21"	"35.11"	"10"	"8"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01092"	"6194"	"ENSG00000137154"	"RPS6"	"hsa:6194; P08227; P10660; P62753; Q4VBY7; Q8N6Z7"	"IL-5 signaling pathway; Thyroid stimulating hormone (TSH) signaling pathway; Leptin signaling pathway; Follicle stimulating hormone (FSH) signaling pathway; Prolactin signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; Interleukin-11 signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Kit receptor signaling pathway; MECP2 and associated Rett syndrome; VEGFA-VEGFR2 signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Thermogenesis; Translation inhibitors in chronically activated PDGFRA cells; Gastrin signaling pathway; Head and neck squamous cell carcinoma; Thyroid hormones production and peripheral downstream signaling effects; Cytoplasmic ribosomal proteins; EGFR tyrosine kinase inhibitor resistance; IL-2 signaling pathway; Pleural mesothelioma; 2q37 copy number variation syndrome; A network map of Macrophage-stimulating protein (MSP) signaling; Interferon type I signaling pathways"	"Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SARS-CoV-2 modulates host translation machinery; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; mTORC1-mediated signalling; rRNA modification in the nucleus and cytosol; Nuclear events stimulated by ALK signaling in cancer; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"47"	"0"	"1503.6"	"1401.8"	"1420.2"	"1308.4"	"1365.1"	"1405.2"	"1778.3"	"2326.3"	"2150.3"	"4113.4"	"6339.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46060"	"Ran GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RANGAP1 PE=1 SV=1"	"0.000"	""	"19"	"9"	"19"	"9"	"587"	"63.5"	"4.68"	"3280.75"	"35.06"	"8"	"9"	"protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf07834, Pf13516"	"5905"	"ENSG00000100401"	"RANGAP1"	"hsa:5905; P46060; Q96JJ2"	"22q11.2 copy number variation syndrome; IL-18 signaling pathway"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Rev-mediated nuclear export of HIV RNA; SUMOylation of DNA replication proteins; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Postmitotic nuclear pore complex (NPC) reformation; SUMOylation of nuclear envelope proteins"	"12"	"0"	"374.5"	"248.2"	"368.7"	"334.9"	"332.7"	"326.7"	"464.8"	"684.2"	"711.9"	"1550.8"	"2223.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75400"	"Pre-mRNA-processing factor 40 homolog A OS=Homo sapiens OX=9606 GN=PRPF40A PE=1 SV=2"	"0.000"	""	"14"	"15"	"24"	"15"	"957"	"108.7"	"7.56"	"4687.72"	"35.02"	"13"	"11"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	"Pf00397, Pf01846"	"55660"	"ENSG00000196504"	"PRPF40A"	"hsa:55660; O43856; O75400; O75404; Q8TBQ1; Q9H782; Q9NWU9; Q9P0Q2; Q9Y5A8"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"1384.5"	"1046.7"	"1273.0"	"1162.7"	"1164.4"	"1161.2"	"1586.3"	"2833.9"	"2610.7"	"6063.9"	"8718.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y314"	"Nitric oxide synthase-interacting protein OS=Homo sapiens OX=9606 GN=NOSIP PE=1 SV=1"	"0.000"	""	"32"	"7"	"16"	"7"	"301"	"33.2"	"8.82"	"2810.72"	"34.94"	"5"	"7"	"other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf15906"	"51070"	"ENSG00000142546"	"NOSIP"	"hsa:51070; Q96FD2; Q9Y314"	""	"NOSIP mediated eNOS trafficking"	"1"	"0"	"700.9"	"611.6"	"700.8"	"639.4"	"663.2"	"702.2"	"842.2"	"1616.6"	"1462.8"	"2223.4"	"2525.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9ULC4"	"Malignant T-cell-amplified sequence 1 OS=Homo sapiens OX=9606 GN=MCTS1 PE=1 SV=1"	"0.000"	""	"43"	"6"	"18"	"6"	"181"	"20.5"	"8.82"	"3804.42"	"34.93"	"6"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"other cell component"	"nucleic acid binding activity"	"Pf01472, Pf17832"	"28985"	"ENSG00000232119; ENSG00000288295"	"MCTS1"	"B4DGY2; hsa:28985; Q502X6; Q9ULC4"	""	""	"0"	"0"	"188.6"	"137.5"	"203.1"	"195.4"	"176.5"	"184.2"	"243.2"	"1560.9"	"1718.6"	"4748.8"	"5366.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15056"	"Eukaryotic translation initiation factor 4H OS=Homo sapiens OX=9606 GN=EIF4H PE=1 SV=5"	"0.000"	""	"46"	"8"	"16"	"8"	"248"	"27.4"	"7.23"	"2760.22"	"34.92"	"5"	"7"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"7458"	"ENSG00000106682"	"EIF4H"	"A8K3R1; D3DXF6; D3DXF8; hsa:7458; Q15056"	"Translation factors; 7q11.23 copy number variation syndrome"	"L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Translation initiation complex formation; Ribosomal scanning and start codon recognition"	"7"	"0"	"341.4"	"260.2"	"304.8"	"297.1"	"292.9"	"294.7"	"400.8"	"1300.6"	"1341.9"	"4245.4"	"4955.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P26038"	"Moesin OS=Homo sapiens OX=9606 GN=MSN PE=1 SV=3"	"0.000"	""	"28"	"17"	"28"	"8"	"577"	"67.8"	"6.40"	"6931.74"	"34.89"	"17"	"9"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00373, Pf00769, Pf09379, Pf09380, Pf20492"	"4478"	"ENSG00000147065"	"MSN"	"hsa:4478; P26038"	"Glial cell differentiation; AGE/RAGE pathway; Measles virus infection; 16p11.2 proximal deletion syndrome; Regulation of actin cytoskeleton"	"Recycling pathway of L1; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Signaling by ALK fusions and activated point mutants"	"10"	"0"	"611.4"	"512.9"	"676.8"	"619.7"	"646.2"	"661.3"	"824.9"	"1837.9"	"1833.7"	"2779.7"	"2585.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96E39"	"RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1"	"0.000"	""	"24"	"8"	"21"	"2"	"390"	"42.1"	"9.89"	"3801.65"	"34.86"	"8"	"8"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf08081"	"494115"	"ENSG00000213516"	"RBMXL1"	"hsa:494115; Q96E39"	""	""	"0"	"0"	"314.6"	"308.3"	"344.5"	"300.4"	"299.7"	"291.8"	"395.1"	"471.4"	"419.1"	"851.3"	"1337.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62857"	"40S ribosomal protein S28 OS=Homo sapiens OX=9606 GN=RPS28 PE=1 SV=1"	"0.000"	""	"72"	"7"	"18"	"7"	"69"	"7.8"	"10.70"	"3857.70"	"34.77"	"7"	"7"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01200"	"6234"	"ENSG00000233927"	"RPS28"	"hsa:6234; P25112; P62857"	"Cytoplasmic ribosomal proteins"	"SRP-dependent cotranslational protein targeting to membrane; SARS-CoV-1 modulates host translation machinery; Major pathway of rRNA processing in the nucleolus and cytosol; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"19"	"0"	"1027.9"	"749.3"	"861.1"	"793.0"	"767.1"	"744.2"	"995.7"	"1299.2"	"1277.2"	"2315.5"	"3185.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6I3"	"Epsin-1 OS=Homo sapiens OX=9606 GN=EPN1 PE=1 SV=2"	"0.000"	""	"22"	"8"	"12"	"8"	"576"	"60.3"	"4.83"	"1376.30"	"34.75"	"4"	"8"	"transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle"	"other molecular function"	"Pf01417, Pf02809"	"29924"	"ENSG00000063245"	"EPN1"	"hsa:29924; Q86ST3; Q9HA18; Q9Y6I3"	"VEGFA-VEGFR2 signaling; EGF/EGFR signaling pathway"	"Cargo recognition for clathrin-mediated endocytosis; EGFR downregulation"	"5"	"0"	"216.9"	"181.9"	"300.0"	"362.8"	"589.9"	"918.0"	"1269.1"	"1673.9"	"1574.8"	"2450.6"	"2604.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P27348"	"14-3-3 protein theta OS=Homo sapiens OX=9606 GN=YWHAQ PE=1 SV=1"	"0.000"	""	"29"	"7"	"22"	"4"	"245"	"27.7"	"4.78"	"3973.51"	"34.44"	"7"	"6"	"transport;signal transduction;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00244"	"10971"	"ENSG00000134308"	"YWHAQ"	"D6W4Z5; hsa:10971; P27348; Q567U5; Q5TZU8; Q9UP48"	"Cell cycle; Pathogenic Escherichia coli infection; Primary focal segmental glomerulosclerosis (FSGS); IL-3 signaling pathway; Myometrial relaxation and contraction pathways; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-YAP signaling; Leukocyte-intrinsic Hippo pathway functions; Hepatitis B infection; Opioid receptor pathways; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Regulation of localization of FOXO transcription factors; TP53 Regulates Metabolic Genes; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Activation of BAD and translocation to mitochondria"	"20"	"0"	"327.8"	"260.0"	"322.8"	"301.8"	"315.7"	"417.1"	"665.4"	"782.0"	"745.2"	"1462.3"	"2065.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60231"	"Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2"	"0.000"	""	"13"	"10"	"20"	"10"	"1041"	"119.2"	"6.80"	"4213.35"	"34.23"	"9"	"8"	"RNA metabolism OR transcription;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"8449"	"ENSG00000204560; ENSG00000206486; ENSG00000226171; ENSG00000231377; ENSG00000233049; ENSG00000233418; ENSG00000233561"	"DHX16"	"hsa:8449; O60231; O60322; Q5JP45; Q969X7; Q96QC1"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"520.8"	"395.7"	"500.2"	"507.7"	"500.1"	"492.4"	"627.6"	"1468.4"	"1489.0"	"2716.1"	"3114.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62136"	"Serine/threonine-protein phosphatase PP1-alpha catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CA PE=1 SV=1"	"0.000"	""	"26"	"7"	"18"	"3"	"330"	"37.5"	"6.33"	"3734.86"	"34.22"	"7"	"7"	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00149, Pf16891"	"5499"	"ENSG00000172531"	"PPP1CA"	"A6NNR3; B2R908; hsa:5499; P08129; P20653; P22802; P62136; Q07161"	"Sphingolipid pathway; Nicotine effect on dopaminergic neurons; Common pathways underlying drug addiction; Focal adhesion; VEGFA-VEGFR2 signaling; Hippo-Merlin signaling dysregulation; Fragile X syndrome; Netrin-UNC5B signaling pathway; Neuroinflammation and glutamatergic signaling"	"Triglyceride catabolism; Circadian Clock; Downregulation of TGF-beta receptor signaling; DARPP-32 events"	"13"	"4"	"581.1"	"493.7"	"613.6"	"575.0"	"534.5"	"537.9"	"675.5"	"1398.2"	"1494.9"	"3735.3"	"4773.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P04637"	"Cellular tumor antigen p53 OS=Homo sapiens OX=9606 GN=TP53 PE=1 SV=4"	"0.000"	""	"24"	"9"	"19"	"9"	"393"	"43.6"	"6.79"	"3534.30"	"34.21"	"9"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00870, Pf07710, Pf08563, Pf18521"	"7157"	"ENSG00000141510"	"TP53"	"hsa:7157; P04637; Q15086; Q15087; Q15088; Q16535; Q16807; Q16808; Q16809; Q16810; Q16811; Q16848; Q2XN98; Q3LRW1; Q3LRW2; Q3LRW3; Q3LRW4; Q3LRW5; Q86UG1; Q8J016; Q99659; Q9BTM4; Q9HAQ8; Q9NP68; Q9NPJ2; Q9NZD0; Q9UBI2; Q9UQ61"	"AMP-activated protein kinase signaling; miRNA regulation of DNA damage response; miRNAs involved in DNA damage response; Fluoropyrimidine activity; TP53 network; Folate metabolism; Apoptosis modulation and signaling; Cell cycle; Metastatic brain tumor; Glioblastoma signaling pathways; Gastric cancer network 2; Oncostatin M signaling pathway; Spinal cord injury; Retinoblastoma gene in cancer; Amyotrophic lateral sclerosis (ALS); ATM signaling pathway; Apoptosis; Mammary gland development pathway - Involution (Stage 4 of 4); Bladder cancer; Copper homeostasis; RAC1/PAK1/p38/MMP2 pathway; Photodynamic therapy-induced HIF-1 survival signaling; Hepatitis C and hepatocellular carcinoma; Pathways affected in adenoid cystic carcinoma; lncRNA-mediated mechanisms of therapeutic resistance; MAPK signaling pathway; miRNA regulation of p53 pathway in prostate cancer; Wnt signaling pathway and pluripotency; Endometrial cancer; PI3K-Akt signaling pathway; Caloric restriction and aging; Chromosomal and microsatellite instability in colorectal cancer ; Epithelial to mesenchymal transition in colorectal cancer; Non-small cell lung cancer; Breast cancer pathway; Pancreatic adenocarcinoma pathway; Ultraconserved region 339 modulation of tumor suppressor microRNAs in cancer; Ferroptosis; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; MicroRNA network associated with chronic lymphocytic leukemia; G1 to S cell cycle control; Measles virus infection; 22q11.2 copy number variation syndrome; Small cell lung cancer; Head and neck squamous cell carcinoma; Melanoma; Thyroid hormones production and peripheral downstream signaling effects; Netrin-UNC5B signaling pathway; IL-18 signaling pathway; Unfolded protein response; 16p11.2 proximal deletion syndrome; Pentose phosphate pathway in senescent cells; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Glycolysis in senescence; TCA cycle in senescence; Pleural mesothelioma; Lipid metabolism in senescent cells; DYRK1A involvement regarding cell proliferation in brain development; 2q37 copy number variation syndrome; Autophagy in pancreatic ductal adenocarcinoma; 11p11.2 copy number variation syndrome ; A network map of Macrophage-stimulating protein (MSP) signaling; ErbB signaling pathway; DNA damage response; DNA damage response (only ATM dependent)"	"TP53 Regulates Transcription of DNA Repair Genes; Regulation of PTEN gene transcription; Factors involved in megakaryocyte development and platelet production; TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest; Autodegradation of the E3 ubiquitin ligase COP1; Ub-specific processing proteases; The role of GTSE1 in G2/M progression after G2 checkpoint; TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain; Regulation of TP53 Degradation; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; TP53 Regulates Transcription of Death Receptors and Ligands; Oxidative Stress Induced Senescence; Regulation of TP53 Activity through Phosphorylation; TP53 Regulates Metabolic Genes; Association of TriC/CCT with target proteins during biosynthesis; Interleukin-4 and Interleukin-13 signaling; Pre-NOTCH Transcription and Translation; Oncogene Induced Senescence; Transcriptional Regulation by VENTX; TP53 Regulates Transcription of Caspase Activators and Caspases; Regulation of TP53 Activity through Methylation; G2/M DNA damage checkpoint; Regulation of NF-kappa B signaling; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Activation of PUMA and translocation to mitochondria; TP53 Regulates Transcription of Genes Involved in Cytochrome C Release; TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain; Regulation of TP53 Activity through Association with Co-factors; Ovarian tumor domain proteases; Pyroptosis; SUMOylation of transcription factors; Regulation of TP53 Expression; RUNX3 regulates CDKN1A transcription; Activation of NOXA and translocation to mitochondria; Formation of Senescence-Associated Heterochromatin Foci (SAHF); PI5P Regulates TP53 Acetylation; Transcriptional  activation of  cell cycle inhibitor p21 ; Loss of function of TP53 in cancer due to loss of tetramerization ability"	"107"	"0"	"648.3"	"543.4"	"701.2"	"657.9"	"638.8"	"599.8"	"861.4"	"1208.4"	"1154.1"	"2575.9"	"4083.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15019"	"Septin-2 OS=Homo sapiens OX=9606 GN=SEPTIN2 PE=1 SV=1"	"0.000"	""	"35"	"11"	"20"	"11"	"361"	"41.5"	"6.60"	"4469.58"	"34.11"	"9"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00735"	"4735"	"ENSG00000168385"	"SEPTIN2"	"B4DGE8; hsa:4735; Q14132; Q15019; Q53QU3; Q8IUK9; Q96CB0"	"2q37 copy number variation syndrome"	"Anchoring of the basal body to the plasma membrane"	"2"	"0"	"1026.0"	"836.7"	"952.0"	"857.1"	"909.9"	"940.4"	"1311.2"	"3135.1"	"3109.8"	"5739.6"	"7755.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P98175"	"RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3"	"0.000"	""	"13"	"11"	"20"	"11"	"930"	"103.5"	"5.97"	"3966.16"	"34.06"	"10"	"8"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00641, Pf01585, Pf17780"	"8241"	"ENSG00000182872"	"RBM10"	"A0A0A0MR66; C4AM81; hsa:8241; P98175; Q14136; Q5JRR2; Q9BTE4; Q9BTX0; Q9NTB1"	""	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"2"	"0"	"1409.0"	"1012.5"	"1347.6"	"1348.0"	"1239.5"	"1148.7"	"1524.4"	"2187.6"	"2204.2"	"4610.6"	"5869.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P57721"	"Poly(rC)-binding protein 3 OS=Homo sapiens OX=9606 GN=PCBP3 PE=1 SV=2"	"0.000"	""	"20"	"7"	"16"	"1"	"371"	"39.4"	"8.07"	"3626.36"	"34.02"	"6"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013"	"54039"	"ENSG00000183570"	"PCBP3"	"A8MPS2; A8MQ26; B7WNN9; B7WPC1; hsa:54039; P57721; Q8N9K6; Q96EP6"	""	""	"0"	"0"	"39.6"	"29.6"	"50.5"	"42.6"	"44.4"	"32.6"	"55.0"	"108.9"	"99.4"	"281.6"	"409.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6L8Q7"	"2',5'-phosphodiesterase 12 OS=Homo sapiens OX=9606 GN=PDE12 PE=1 SV=2"	"0.000"	""	"22"	"10"	"17"	"10"	"609"	"67.3"	"6.57"	"2926.04"	"33.91"	"8"	"9"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf03372"	"201626"	"ENSG00000174840"	"PDE12"	"B4DTU8; hsa:201626; Q6L8Q7; Q8IYU3; Q8NDU2; Q8TE78"	"Phosphodiesterases in neuronal function"	"OAS antiviral response"	"2"	"0"	"495.0"	"337.3"	"447.2"	"426.2"	"427.3"	"416.0"	"550.4"	"1530.0"	"1499.7"	"3949.9"	"5928.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94973"	"AP-2 complex subunit alpha-2 OS=Homo sapiens OX=9606 GN=AP2A2 PE=1 SV=2"	"0.000"	""	"13"	"10"	"20"	"7"	"939"	"103.9"	"6.96"	"3616.37"	"33.90"	"9"	"9"	"transport"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01602, Pf02296, Pf02883"	"161"	"ENSG00000183020"	"AP2A2"	"hsa:161; O75403; O94973; Q53ET1; Q96SI8"	"Synaptic vesicle pathway; GABA receptor signaling; mBDNF and proBDNF regulation of GABA neurotransmission"	"Potential therapeutics for SARS; Recycling pathway of L1; MHC class II antigen presentation; Neutrophil degranulation; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; LDL clearance; Nef Mediated CD4 Down-regulation; Retrograde neurotrophin signalling; Nef Mediated CD8 Down-regulation; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; VLDLR internalisation and degradation"	"17"	"0"	"251.3"	"204.8"	"262.6"	"260.4"	"251.4"	"481.8"	"868.0"	"1904.7"	"1685.2"	"2055.1"	"2167.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P36776"	"Lon protease homolog, mitochondrial OS=Homo sapiens OX=9606 GN=LONP1 PE=1 SV=2"	"0.000"	""	"9"	"9"	"19"	"9"	"959"	"106.4"	"6.39"	"3008.28"	"33.85"	"7"	"9"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00004, Pf02190, Pf05362"	"9361"	"ENSG00000196365"	"LONP1"	"B3KPH8; D6W635; E5KMH8; F5GZ27; hsa:9361; P36776; P36777; Q8N8K8; Q9UQ95"	""	""	"0"	"0"	"195.6"	"149.5"	"195.9"	"195.2"	"184.3"	"174.7"	"230.7"	"788.7"	"906.9"	"4481.4"	"6470.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16775"	"Hydroxyacylglutathione hydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=HAGH PE=1 SV=2"	"0.000"	""	"26"	"5"	"13"	"5"	"308"	"33.8"	"8.12"	"2238.22"	"33.85"	"3"	"5"	"other metabolic processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00753, Pf16123"	"3029"	"ENSG00000063854"	"HAGH"	"A8K290; B4DP33; B4DRA7; E7EN93; hsa:3029; Q16775"	""	""	"0"	"0"	"203.8"	"178.4"	"206.1"	"202.0"	"193.5"	"206.7"	"242.2"	"365.7"	"382.1"	"812.3"	"1177.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55081"	"Microfibrillar-associated protein 1 OS=Homo sapiens OX=9606 GN=MFAP1 PE=1 SV=2"	"0.000"	""	"26"	"10"	"17"	"10"	"439"	"51.9"	"4.98"	"3001.44"	"33.80"	"8"	"7"	"RNA metabolism OR transcription;other metabolic processes"	"extracellular matrix;cytoskeleton;nucleus"	""	"Pf06991"	"4236"	"ENSG00000140259"	"MFAP1"	"hsa:4236; P55081; Q86TG6"	"Canonical and non-canonical Notch signaling; Ciliary landscape"	"mRNA Splicing - Major Pathway"	"3"	"0"	"1433.0"	"1303.6"	"1422.1"	"1379.1"	"1333.3"	"1327.8"	"1633.5"	"1953.5"	"1849.5"	"3556.0"	"4710.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96T37"	"RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2"	"0.000"	""	"10"	"8"	"16"	"8"	"977"	"107.1"	"10.08"	"2443.14"	"33.76"	"7"	"8"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"other membranes;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf07744"	"64783"	"ENSG00000162775"	"RBM15"	"A1A693; hsa:64783; Q3ZB86; Q4V760; Q5D058; Q5T613; Q86VW9; Q96PE4; Q96SC5; Q96SC6; Q96SC9; Q96SD0; Q96T37; Q96T38; Q9BRA5; Q9H6R8; Q9H9Y0"	""	""	"0"	"0"	"529.0"	"375.9"	"552.6"	"496.6"	"499.8"	"597.4"	"893.2"	"1590.1"	"1511.9"	"2477.1"	"2806.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95782"	"AP-2 complex subunit alpha-1 OS=Homo sapiens OX=9606 GN=AP2A1 PE=1 SV=3"	"0.000"	""	"13"	"11"	"23"	"8"	"977"	"107.5"	"7.03"	"3911.92"	"33.69"	"10"	"9"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01602, Pf02296, Pf02883"	"160"	"ENSG00000196961"	"AP2A1"	"hsa:160; O95782; Q96CI7; Q96PP6; Q96PP7; Q9H070"	"Synaptic vesicle pathway; VEGFA-VEGFR2 signaling; GABA receptor signaling; EGF/EGFR signaling pathway; Fragile X syndrome; mBDNF and proBDNF regulation of GABA neurotransmission"	"Potential therapeutics for SARS; Recycling pathway of L1; MHC class II antigen presentation; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; LDL clearance; Trafficking of GluR2-containing AMPA receptors; Nef Mediated CD4 Down-regulation; Retrograde neurotrophin signalling; Nef Mediated CD8 Down-regulation; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; VLDLR internalisation and degradation"	"20"	"3"	"463.3"	"403.8"	"496.1"	"466.4"	"464.6"	"915.8"	"1945.5"	"4281.6"	"3732.7"	"3770.8"	"3452.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14654"	"Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1"	"0.000"	""	"9"	"11"	"16"	"11"	"1257"	"133.7"	"8.44"	"1808.51"	"33.68"	"6"	"10"	"signal transduction"	"plasma membrane;other membranes;cytosol"	"signal transduction activity or receptor binding;other molecular function"	"Pf02174"	"8471"	"ENSG00000133124"	"IRS4"	"hsa:8471; O14654"	"Alzheimer's disease and miRNA effects; Adipogenesis; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Leptin-insulin signaling overlap; Insulin signaling; Alzheimer's disease"	"IRS-related events triggered by IGF1R"	"8"	"0"	"1401.4"	"1140.4"	"1220.5"	"1199.9"	"1104.2"	"1137.9"	"1498.0"	"2447.0"	"2362.4"	"4731.8"	"5977.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61247"	"40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2"	"0.000"	""	"42"	"13"	"24"	"13"	"264"	"29.9"	"9.73"	"3904.28"	"33.59"	"10"	"11"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01015"	"6189"	"ENSG00000145425"	"RPS3A"	"B2R4D4; D3DP05; hsa:6189; P33443; P49241; P61247"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Peptide chain elongation; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"1850.8"	"1655.8"	"1856.7"	"1676.2"	"1729.8"	"1836.8"	"2388.7"	"3059.5"	"2885.7"	"5990.2"	"9267.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62826"	"GTP-binding nuclear protein Ran OS=Homo sapiens OX=9606 GN=RAN PE=1 SV=3"	"0.000"	""	"24"	"5"	"13"	"5"	"216"	"24.4"	"7.49"	"1406.25"	"33.54"	"3"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00071"	"5901"	"ENSG00000132341"	"RAN"	"A8K3Z8; hsa:5901; P17080; P28746; P28747; P62826; Q6IPB2; Q86V08; Q8NI90; Q9CSP3; Q9CWI7; Q9CZA2; Q9UDJ5; Q9UEU9"	"Androgen receptor signaling pathway; miRNA biogenesis; 22q11.2 copy number variation syndrome"	"Rev-mediated nuclear export of HIV RNA; NEP/NS2 Interacts with the Cellular Export Machinery; Nuclear import of Rev protein; Transcriptional regulation by small RNAs; tRNA processing in the nucleus; Regulation of cholesterol biosynthesis by SREBP (SREBF); MicroRNA (miRNA) biogenesis; Postmitotic nuclear pore complex (NPC) reformation"	"11"	"0"	"697.2"	"625.3"	"629.4"	"558.4"	"570.3"	"566.5"	"837.8"	"1215.5"	"1138.5"	"2467.7"	"3130.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51610"	"Host cell factor 1 OS=Homo sapiens OX=9606 GN=HCFC1 PE=1 SV=2"	"0.000"	""	"6"	"10"	"19"	"10"	"2035"	"208.6"	"7.46"	"3723.22"	"33.48"	"9"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf01344, Pf13415"	"3054"	"ENSG00000172534"	"HCFC1"	"hsa:3054; P51610; Q6P4G5"	"Mitochondrial gene expression; Pleural mesothelioma"	"UCH proteinases; Formation of WDR5-containing histone-modifying complexes; Transcriptional activation of mitochondrial biogenesis; HATs acetylate histones"	"6"	"0"	"762.1"	"684.8"	"811.3"	"664.1"	"740.8"	"753.6"	"948.1"	"1469.9"	"1448.1"	"3131.8"	"4624.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13148"	"TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1"	"0.000"	""	"24"	"8"	"18"	"8"	"414"	"44.7"	"6.19"	"3695.91"	"33.48"	"5"	"7"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf18694"	"23435"	"ENSG00000120948"	"TARDBP"	"A4GUK4; A4GUK5; A4GUK6; B2R629; B4DJ45; E2PU12; hsa:23435; Q13148; Q53H27; Q6FI92; Q96DJ0"	"MECP2 and associated Rett syndrome"	""	"1"	"0"	"826.6"	"639.3"	"851.4"	"757.9"	"740.3"	"770.7"	"1048.9"	"1514.1"	"1478.2"	"3409.7"	"5105.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKY7"	"Protein CDV3 homolog OS=Homo sapiens OX=9606 GN=CDV3 PE=1 SV=1"	"0.000"	""	"28"	"7"	"16"	"7"	"258"	"27.3"	"6.40"	"3957.74"	"33.38"	"7"	"7"	""	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf15359"	"55573"	"ENSG00000091527"	"CDV3"	"B3KUC2; hsa:55573; Q96IP9; Q9UKY7"	""	""	"0"	"0"	"209.8"	"166.7"	"220.5"	"207.3"	"192.8"	"249.0"	"339.4"	"3083.8"	"3140.2"	"6684.2"	"7282.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16531"	"DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1"	"0.000"	""	"11"	"12"	"21"	"12"	"1140"	"126.9"	"5.26"	"3469.47"	"33.32"	"10"	"11"	"cell-cell signaling;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03178, Pf10433"	"1642"	"ENSG00000167986"	"DDB1"	"A6NG77; B2R648; B4DG00; hsa:1642; O15176; Q13289; Q16531; Q58F96"	"Hippo-Merlin signaling dysregulation; Hepatitis B infection; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"Neddylation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; DNA Damage Recognition in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; Dual Incision in GG-NER"	"14"	"0"	"683.3"	"571.9"	"725.2"	"650.3"	"611.8"	"653.1"	"821.2"	"1588.3"	"1567.0"	"4612.6"	"7340.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P06454"	"Prothymosin alpha OS=Homo sapiens OX=9606 GN=PTMA PE=1 SV=2"	"0.000"	""	"23"	"4"	"14"	"4"	"111"	"12.2"	"3.78"	"3674.39"	"33.29"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf03247"	"5757"	"ENSG00000187514"	"PTMA"	"hsa:5757; P06454; Q15249; Q15592"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"831.4"	"596.2"	"700.8"	"730.3"	"716.7"	"726.9"	"871.5"	"862.8"	"860.5"	"1012.2"	"1149.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49591"	"Serine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=SARS1 PE=1 SV=3"	"0.000"	""	"24"	"12"	"21"	"12"	"514"	"58.7"	"6.43"	"4893.98"	"33.26"	"10"	"9"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00587, Pf02403"	"6301"	"ENSG00000031698"	"SARS1"	"B2R6Y9; hsa:6301; P49591; Q5T5C8; Q9NSE3"	"VEGFA-VEGFR2 signaling"	"Cytosolic tRNA aminoacylation; Selenocysteine synthesis"	"3"	"0"	"689.0"	"524.2"	"547.3"	"551.3"	"542.0"	"603.9"	"774.7"	"2483.2"	"2580.4"	"4744.5"	"5389.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q09028"	"Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3"	"0.000"	""	"19"	"9"	"22"	"3"	"425"	"47.6"	"4.89"	"3692.51"	"33.25"	"9"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400, Pf12265"	"5928"	"ENSG00000162521"	"RBBP4"	"B2R6G9; B4DRH0; D3DPQ3; hsa:5928; P31149; Q09028; Q53H02; Q96BV9"	"Retinoblastoma gene in cancer; Interactome of polycomb repressive complex 2 (PRC2) ; Tumor suppressor activity of SMARCB1; Epithelial to mesenchymal transition in colorectal cancer; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; Pleural mesothelioma; DYRK1A involvement regarding cell proliferation in brain development"	"Activation of anterior HOX genes in hindbrain development during early embryogenesis; HCMV Early Events; Potential therapeutics for SARS; Deposition of new CENPA-containing nucleosomes at the centromere; Oxidative Stress Induced Senescence; HDACs deacetylate histones; PRC2 methylates histones and DNA; Defective pyroptosis; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6; PKMTs methylate histone lysines; RNA Polymerase I Transcription Initiation; G1/S-Specific Transcription; Regulation of TP53 Activity through Acetylation; Polo-like kinase mediated events; Cyclin E associated events during G1/S transition ; Transcription of E2F targets under negative control by DREAM complex; Cyclin A:Cdk2-associated events at S phase entry; Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"	"28"	"7"	"1468.9"	"1147.7"	"1315.0"	"1220.0"	"1096.3"	"1204.4"	"1596.5"	"2567.3"	"2323.0"	"5287.0"	"7255.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96CW1"	"AP-2 complex subunit mu OS=Homo sapiens OX=9606 GN=AP2M1 PE=1 SV=2"	"0.000"	""	"20"	"7"	"17"	"7"	"435"	"49.6"	"9.54"	"3634.92"	"33.09"	"6"	"6"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00928, Pf01217"	"1173"	"ENSG00000161203"	"AP2M1"	"A6NE12; D3DNT1; hsa:1173; P20172; P53679; Q96CW1"	"Synaptic vesicle pathway; GABA receptor signaling; EGF/EGFR signaling pathway; Fragile X syndrome; GDNF signaling"	"Potential therapeutics for SARS; EPH-ephrin mediated repulsion of cells; Cargo recognition for clathrin-mediated endocytosis; VLDLR internalisation and degradation; Recycling pathway of L1; MHC class II antigen presentation; WNT5A-dependent internalization of FZD4; LDL clearance; Nef Mediated CD4 Down-regulation; Retrograde neurotrophin signalling; Nef Mediated CD8 Down-regulation; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; Nef mediated downregulation of CD28 cell surface expression; Formation of annular gap junctions"	"21"	"0"	"194.9"	"177.4"	"244.8"	"218.4"	"234.2"	"465.0"	"895.9"	"2179.5"	"1815.7"	"1997.0"	"2055.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BZZ5"	"Apoptosis inhibitor 5 OS=Homo sapiens OX=9606 GN=API5 PE=1 SV=3"	"0.000"	""	"22"	"11"	"18"	"11"	"524"	"59.0"	"7.34"	"4229.17"	"33.04"	"9"	"9"	"other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf05918"	"8539"	"ENSG00000166181"	"API5"	"B4DGR0; B4DRJ2; B4E283; D3DR21; G3V1C3; hsa:8539; O15441; Q9BZZ5; Q9Y4J7"	""	""	"0"	"0"	"738.8"	"611.3"	"791.3"	"615.1"	"661.6"	"699.7"	"919.8"	"1562.4"	"1669.2"	"4214.9"	"6136.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35659"	"Protein DEK OS=Homo sapiens OX=9606 GN=DEK PE=1 SV=1"	"0.000"	""	"22"	"9"	"18"	"9"	"375"	"42.6"	"8.56"	"3605.44"	"32.81"	"8"	"8"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytoskeleton;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf08766"	"7913"	"ENSG00000124795"	"DEK"	"B2R6K6; B4DN37; hsa:7913; P35659; Q5TGV4; Q5TGV5"	"IL-18 signaling pathway; 10q11.21q11.23 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression; Transcriptional regulation of granulopoiesis; Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors"	"5"	"0"	"318.6"	"247.5"	"310.6"	"281.5"	"275.1"	"302.8"	"380.8"	"1822.2"	"1866.8"	"8988.1"	"7593.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05023"	"Sodium/potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1"	"0.000"	""	"9"	"8"	"19"	"8"	"1023"	"112.8"	"5.49"	"3835.89"	"32.81"	"8"	"7"	"transport;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;other cell component"	"transporter activity;other molecular function"	"Pf00122, Pf00689, Pf00690, Pf13246"	"476"	"ENSG00000163399"	"ATP1A1"	"B2RBR6; B7Z2T5; B7Z3U6; F5H3A1; hsa:476; P05023; Q16689; Q6LDM4; Q9UCN1; Q9UJ20; Q9UJ21"	"Pre-implantation embryo; Proximal tubule transport; Arsenic metabolism and reactive oxygen species generation"	"Potential therapeutics for SARS; Ion homeostasis; Ion transport by P-type ATPases"	"6"	"0"	"452.1"	"317.1"	"458.3"	"442.4"	"396.0"	"372.3"	"505.5"	"1188.4"	"1277.2"	"3601.5"	"4840.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12959"	"Disks large homolog 1 OS=Homo sapiens OX=9606 GN=DLG1 PE=1 SV=2"	"0.000"	""	"13"	"8"	"15"	"8"	"904"	"100.4"	"5.76"	"2693.27"	"32.79"	"7"	"8"	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"extracellular matrix;plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;kinase activity;other molecular function"	"Pf00018, Pf00595, Pf00625, Pf09058, Pf10600, Pf10608"	"1739"	"ENSG00000075711"	"DLG1"	"A5YKK7; B4DGU1; B4DGZ8; B7ZMM0; B9EIQ5; D3DXB8; D3DXB9; E7EWL7; E9PG21; hsa:1739; Q12958; Q12959"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection; Disruption of postsynaptic signaling by CNV; 3q29 copy number variation syndrome"	"Assembly and cell surface presentation of NMDA receptors; RAF/MAP kinase cascade; Ras activation upon Ca2+ influx through NMDA receptor; Unblocking of NMDA receptors, glutamate binding and activation; Synaptic adhesion-like molecules; Negative regulation of NMDA receptor-mediated neuronal transmission; Long-term potentiation; Trafficking of AMPA receptors; NrCAM interactions; Activation of Ca-permeable Kainate Receptor"	"14"	"0"	"273.0"	"212.6"	"280.5"	"271.9"	"267.4"	"271.3"	"342.5"	"924.1"	"955.9"	"2177.8"	"2814.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P78406"	"mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1"	"0.000"	""	"28"	"9"	"18"	"9"	"368"	"40.9"	"7.83"	"4095.06"	"32.77"	"8"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00400"	"8480"	"ENSG00000101146"	"RAE1"	"A8K882; hsa:8480; O15306; P78406; Q3SYL7; Q5TCH8; Q6V708; Q9H100; Q9NQM6"	"IL-18 signaling pathway; SARS-CoV-2 innate immunity evasion and cell-specific immune response"	"ISG15 antiviral mechanism; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Transcriptional regulation by small RNAs; Viral Messenger RNA Synthesis; HCMV Early Events; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; HCMV Late Events; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus"	"30"	"0"	"1454.9"	"961.9"	"1408.5"	"1389.1"	"1307.1"	"1326.1"	"1745.6"	"2896.3"	"2854.7"	"5749.5"	"7489.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12904"	"Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 OS=Homo sapiens OX=9606 GN=AIMP1 PE=1 SV=2"	"0.000"	""	"30"	"9"	"18"	"8"	"312"	"34.3"	"8.43"	"3216.01"	"32.77"	"7"	"9"	"cell-cell signaling;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf01588"	"9255"	"ENSG00000164022"	"AIMP1"	"B3KTR2; B4E1S7; hsa:9255; Q12904; Q6FG28; Q96CQ9"	"Ciliary landscape"	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"3"	"1"	"603.8"	"443.3"	"596.2"	"584.7"	"547.9"	"571.6"	"719.8"	"2003.5"	"2042.4"	"5755.5"	"7478.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P39019"	"40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2"	"0.000"	""	"45"	"9"	"21"	"9"	"145"	"16.1"	"10.32"	"4700.52"	"32.76"	"9"	"9"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01090"	"6223"	"ENSG00000105372"	"RPS19"	"hsa:6223; P39019"	"Complement system; Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"20"	"0"	"1779.8"	"1630.3"	"1830.6"	"1596.7"	"1721.8"	"1734.8"	"2308.5"	"2272.8"	"2201.3"	"2991.2"	"3132.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95831"	"Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1"	"0.000"	""	"17"	"7"	"15"	"7"	"613"	"66.9"	"8.95"	"3083.22"	"32.68"	"6"	"7"	"cell organization and biogenesis;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00070, Pf14721"	"9131"	"ENSG00000156709"	"AIFM1"	"A4QPB4; B1ALN1; B2RB08; D3DTE9; E9PRR0; hsa:9131; O95831; Q1L6K4; Q1L6K6; Q2QKE4; Q5JUZ7; Q6I9X6; Q9Y3I3; Q9Y3I4"	"Apoptosis modulation and signaling; Nanomaterial induced apoptosis; Apoptosis modulation by HSP70"	""	"3"	"0"	"349.1"	"263.8"	"380.5"	"354.4"	"335.7"	"344.2"	"426.1"	"795.8"	"813.0"	"2378.8"	"3600.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P32119"	"Peroxiredoxin-2 OS=Homo sapiens OX=9606 GN=PRDX2 PE=1 SV=5"	"0.000"	""	"26"	"7"	"21"	"6"	"198"	"21.9"	"5.97"	"4568.97"	"32.57"	"7"	"7"	"cell cycle OR cell proliferation;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00578, Pf10417"	"7001"	"ENSG00000167815"	"PRDX2"	"A8K0C0; hsa:7001; P31945; P32118; P32119; P35701; Q6FHG4; Q92763; Q9UC23"	"Selenium micronutrient network; VEGFA-VEGFR2 signaling"	"TP53 Regulates Metabolic Genes; Detoxification of Reactive Oxygen Species; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"	"5"	"0"	"279.3"	"206.6"	"330.5"	"255.8"	"244.8"	"263.2"	"336.5"	"1008.6"	"1206.7"	"3775.8"	"5468.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P12268"	"Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2"	"0.000"	""	"20"	"7"	"15"	"7"	"514"	"55.8"	"6.90"	"4056.03"	"32.56"	"6"	"6"	"cell cycle OR cell proliferation;other metabolic processes;developmental processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00478, Pf00571"	"3615"	"ENSG00000178035"	"IMPDH2"	"hsa:3615; P12268; Q6LEF3"	"Rett syndrome causing genes"	"Potential therapeutics for SARS; Neutrophil degranulation; Purine ribonucleoside monophosphate biosynthesis; Azathioprine ADME"	"5"	"0"	"307.9"	"261.9"	"278.1"	"273.9"	"243.8"	"254.5"	"339.0"	"875.8"	"823.0"	"2542.1"	"4352.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UNS2"	"COP9 signalosome complex subunit 3 OS=Homo sapiens OX=9606 GN=COPS3 PE=1 SV=3"	"0.000"	""	"18"	"5"	"15"	"5"	"423"	"47.8"	"6.65"	"3302.92"	"32.48"	"4"	"5"	"protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf01399"	"8533"	"ENSG00000141030"	"COPS3"	"B2R683; B4DY81; hsa:8533; O43191; Q7LDR6; Q9UNS2"	"Ciliary landscape; Smith-Magenis and Potocki-Lupski syndrome copy number variation"	"Neddylation; Formation of TC-NER Pre-Incision Complex; Cargo recognition for clathrin-mediated endocytosis; DNA Damage Recognition in GG-NER"	"6"	"0"	"136.7"	"120.4"	"151.0"	"149.6"	"134.4"	"175.8"	"217.5"	"517.9"	"514.0"	"1239.9"	"2171.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15371"	"Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1"	"0.000"	""	"22"	"8"	"13"	"8"	"548"	"63.9"	"6.05"	"2093.40"	"32.46"	"5"	"8"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf05091"	"8664"	"ENSG00000100353"	"EIF3D"	"A8MWD3; B2R7D4; B4DTF8; B4DVY1; hsa:8664; O15371; Q3MJD9; Q5M9Q6"	"Translation factors; VEGFA-VEGFR2 signaling; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"9"	"0"	"411.6"	"319.5"	"423.5"	"411.3"	"400.2"	"389.4"	"532.5"	"782.4"	"743.8"	"1570.7"	"3656.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00425"	"Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2"	"0.000"	""	"13"	"6"	"16"	"5"	"579"	"63.7"	"8.87"	"3025.83"	"32.44"	"6"	"6"	"protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf00076"	"10643"	"ENSG00000136231"	"IGF2BP3"	"A0A4Z5; hsa:10643; O00425; Q63HM0; Q6MZZ2; Q86VB1"	""	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"	"1"	"1"	"405.0"	"298.2"	"472.0"	"407.2"	"382.2"	"407.0"	"537.2"	"768.0"	"732.1"	"1582.1"	"2381.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3F4"	"Serine-threonine kinase receptor-associated protein OS=Homo sapiens OX=9606 GN=STRAP PE=1 SV=1"	"0.000"	""	"29"	"6"	"13"	"6"	"350"	"38.4"	"5.12"	"2739.95"	"32.35"	"5"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00400"	"11171"	"ENSG00000023734"	"STRAP"	"B2R5S5; B4DNJ6; hsa:11171; Q5TZT4; Q9NTK0; Q9UQC8; Q9Y3F4"	"Epithelial to mesenchymal transition in colorectal cancer"	"Downregulation of TGF-beta receptor signaling"	"2"	"0"	"322.8"	"251.4"	"288.1"	"285.9"	"267.7"	"279.2"	"347.7"	"676.6"	"660.4"	"1631.9"	"3106.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5S9"	"RNA-binding protein 8A OS=Homo sapiens OX=9606 GN=RBM8A PE=1 SV=1"	"0.000"	""	"31"	"3"	"13"	"3"	"174"	"19.9"	"5.72"	"4371.35"	"32.35"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"9939"	"ENSG00000265241"	"RBM8A"	"B3KQI9; hsa:9939; Q6FHD1; Q6IQ40; Q9GZX8; Q9NZI4; Q9Y5S9"	""	"mRNA Splicing - Major Pathway; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript"	"6"	"0"	"167.5"	"175.5"	"137.2"	"149.4"	"142.8"	"136.0"	"196.6"	"281.3"	"279.2"	"543.2"	"972.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13112"	"Chromatin assembly factor 1 subunit B OS=Homo sapiens OX=9606 GN=CHAF1B PE=1 SV=1"	"0.000"	""	"18"	"8"	"17"	"8"	"559"	"61.5"	"7.50"	"2744.41"	"32.32"	"7"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf00400, Pf15512"	"8208"	"ENSG00000159259"	"CHAF1B"	"hsa:8208; Q13112; Q99548"	""	""	"0"	"0"	"626.3"	"511.9"	"619.3"	"554.4"	"551.7"	"583.3"	"749.8"	"1501.1"	"1489.7"	"2872.2"	"3391.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5UIP0"	"Telomere-associated protein RIF1 OS=Homo sapiens OX=9606 GN=RIF1 PE=1 SV=2"	"0.000"	""	"5"	"8"	"15"	"8"	"2472"	"274.3"	"5.52"	"2930.51"	"32.27"	"7"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	""	"Pf12231"	"55183"	"ENSG00000080345"	"RIF1"	"A6NC27; C9JBR1; hsa:55183; Q5H9R3; Q5UIP0; Q5UIP2; Q66YK6; Q6PRU2; Q8TE94; Q99772; Q9H830; Q9H9B9; Q9NVP5; Q9Y4R4"	"ATM signaling in development and disease ; 10q11.21q11.23 copy number variation syndrome"	"Nonhomologous End-Joining (NHEJ)"	"3"	"0"	"418.4"	"311.5"	"397.4"	"400.2"	"398.4"	"385.8"	"464.6"	"913.1"	"868.1"	"1678.5"	"1976.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16630"	"Cleavage and polyadenylation specificity factor subunit 6 OS=Homo sapiens OX=9606 GN=CPSF6 PE=1 SV=2"	"0.000"	""	"24"	"9"	"15"	"9"	"551"	"59.2"	"7.15"	"2638.16"	"32.25"	"7"	"8"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00076"	"11052"	"ENSG00000111605"	"CPSF6"	"A8K7K9; hsa:11052; Q16630; Q53ES1; Q9BSJ7; Q9BW18"	""	"Signaling by cytosolic FGFR1 fusion mutants; Signaling by FGFR1 in disease"	"2"	"0"	"336.2"	"288.3"	"319.1"	"270.6"	"275.5"	"284.9"	"398.8"	"815.8"	"775.9"	"2569.9"	"4433.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00148"	"ATP-dependent RNA helicase DDX39A OS=Homo sapiens OX=9606 GN=DDX39A PE=1 SV=2"	"0.000"	""	"18"	"9"	"18"	"1"	"427"	"49.1"	"5.68"	"2917.26"	"32.23"	"6"	"8"	"RNA metabolism OR transcription;other metabolic processes;transport"	"nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271"	"10212"	"ENSG00000123136"	"DDX39A"	"B1Q2N1; hsa:10212; O00148; Q8N5M0; Q9BVP6; Q9H5W0"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P31946"	"14-3-3 protein beta/alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3"	"0.000"	""	"32"	"7"	"21"	"3"	"246"	"28.1"	"4.83"	"4108.78"	"32.08"	"7"	"6"	"transport;signal transduction;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00244"	"7529"	"ENSG00000166913"	"YWHAB"	"A8K9K2; E1P616; hsa:7529; P31946"	"Cell cycle; IL-3 signaling pathway; Myometrial relaxation and contraction pathways; Hepatitis B infection; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Regulation of localization of FOXO transcription factors; Signaling by BRAF and RAF1 fusions; mTORC1-mediated signalling; TP53 Regulates Metabolic Genes; Signaling by Hippo; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RAF activation; SHOC2 M1731 mutant abolishes MRAS complex function; Gain-of-function MRAS complexes activate RAF signaling; RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; Rap1 signalling; MAP2K and MAPK activation; Negative regulation of MAPK pathway; Signaling by high-kinase activity BRAF mutants; Frs2-mediated activation; ARMS-mediated activation; Activation of BAD and translocation to mitochondria ; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"	"33"	"0"	"390.5"	"274.2"	"349.4"	"374.9"	"300.5"	"326.7"	"430.1"	"614.6"	"555.2"	"1005.4"	"1296.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07197"	"Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3"	"0.000"	""	"12"	"11"	"21"	"9"	"916"	"102.4"	"4.91"	"4315.84"	"32.06"	"10"	"9"	"cell organization and biogenesis"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf00038, Pf04732"	"4741"	"ENSG00000104722"	"NEFM"	"B4DGN2; E9PBF7; hsa:4741; P07197; Q4QRK6"	"Amyotrophic lateral sclerosis (ALS); Physico-chemical features and toxicity-associated pathways; Ciliary landscape"	""	"3"	"1"	"1389.4"	"1050.3"	"1197.4"	"1123.0"	"1060.1"	"1070.9"	"1389.2"	"2072.3"	"2002.2"	"3193.8"	"4192.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95757"	"Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3"	"0.000"	""	"16"	"10"	"16"	"8"	"839"	"94.5"	"5.88"	"2944.58"	"32.06"	"8"	"8"	"protein metabolism;other metabolic processes;stress response"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00012"	"22824"	"ENSG00000164070"	"HSPA4L"	"A2ICT2; hsa:22824; O95757; Q4W5M5; Q8IWA2"	""	"Regulation of HSF1-mediated heat shock response"	"1"	"0"	"266.9"	"203.3"	"299.9"	"275.4"	"273.0"	"269.5"	"344.1"	"530.0"	"564.8"	"1066.6"	"1497.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WXF1"	"Paraspeckle component 1 OS=Homo sapiens OX=9606 GN=PSPC1 PE=1 SV=1"	"0.000"	""	"16"	"8"	"16"	"7"	"523"	"58.7"	"6.67"	"2241.01"	"32.05"	"7"	"8"	"stress response;other biological processes"	"nucleus;other cell component"	""	"Pf00076, Pf08075"	"55269"	"ENSG00000121390"	"PSPC1"	"hsa:55269; Q5JTQ3; Q8NCZ9; Q8WXE8; Q8WXF1; Q9NV36"	""	""	"0"	"0"	"576.2"	"584.5"	"639.6"	"534.6"	"595.7"	"607.7"	"746.7"	"1056.2"	"993.7"	"2090.4"	"2936.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NBS9"	"Thioredoxin domain-containing protein 5 OS=Homo sapiens OX=9606 GN=TXNDC5 PE=1 SV=2"	"0.000"	""	"24"	"9"	"18"	"9"	"432"	"47.6"	"5.97"	"2469.96"	"31.99"	"7"	"8"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;ER/Golgi;other cytoplasmic organelle"	"other molecular function"	"Pf00085"	"81567"	"ENSG00000239264"	"TXNDC5"	"B2RDM2; hsa:81567; Q5TCQ0; Q8NBS9; Q8ND33; Q8TCT2; Q9BVH9"	"VEGFA-VEGFR2 signaling"	"Golgi Associated Vesicle Biogenesis; Neutrophil degranulation; Lysosome Vesicle Biogenesis"	"4"	"0"	"1108.5"	"1016.4"	"1072.3"	"947.6"	"1012.2"	"1028.2"	"1324.9"	"1797.2"	"1627.1"	"2961.6"	"4360.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9C0J8"	"pre-mRNA 3' end processing protein WDR33 OS=Homo sapiens OX=9606 GN=WDR33 PE=1 SV=2"	"0.000"	""	"8"	"7"	"15"	"7"	"1336"	"145.8"	"9.17"	"3056.96"	"31.99"	"6"	"7"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	""	"Pf00400"	"55339"	"ENSG00000136709"	"WDR33"	"hsa:55339; Q05DP8; Q53FG9; Q587J1; Q69YF7; Q6NUQ0; Q9C0J8; Q9NUL1"	""	"Transport of Mature mRNA Derived from an Intronless Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"5"	"0"	"528.1"	"446.2"	"528.3"	"529.0"	"496.0"	"497.2"	"630.3"	"807.6"	"780.3"	"1545.7"	"2225.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P04908"	"Histone H2A type 1-B/E OS=Homo sapiens OX=9606 GN=H2AC4 PE=1 SV=2"	"0.000"	""	"32"	"4"	"19"	"1"	"130"	"14.1"	"11.05"	"3110.22"	"31.92"	"4"	"4"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125, Pf16211"	"3012; 8335"	"ENSG00000277075; ENSG00000278463"	"H2AC4; H2AC8"	"hsa:3012; hsa:8335; P04908; P28001; Q76P63"	"Proteasome degradation"	"Amyloid fiber formation; Meiotic synapsis; HCMV Late Events; UCH proteinases; Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; HCMV Early Events; Transcriptional regulation by small RNAs; Deposition of new CENPA-containing nucleosomes at the centromere; B-WICH complex positively regulates rRNA expression; Formation of the beta-catenin:TCF transactivating complex; Oxidative Stress Induced Senescence; HDACs deacetylate histones; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Metalloprotease DUBs; Pre-NOTCH Transcription and Translation; Senescence-Associated Secretory Phenotype (SASP); RMTs methylate histone arginines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; HATs acetylate histones; RNA Polymerase I Promoter Escape; Meiotic recombination; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Packaging Of Telomere Ends; Condensation of Prophase Chromosomes; DNA Damage/Telomere Stress Induced Senescence; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis"	"42"	"0"	"37.5"	"86.1"	"47.0"	"35.1"	"48.7"	"39.0"	"53.4"	"94.0"	"78.1"	"124.5"	"207.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92900"	"Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2"	"0.000"	""	"7"	"5"	"11"	"5"	"1129"	"124.3"	"6.61"	"2881.81"	"31.91"	"4"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09416, Pf13086, Pf13087, Pf18141"	"5976"	"ENSG00000005007"	"UPF1"	"hsa:5976; O00239; O43343; Q86Z25; Q92842; Q92900"	"Pathophysiological roles of DUX4 in FSHD1"	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"3"	"0"	"490.2"	"380.4"	"594.4"	"504.6"	"508.9"	"484.3"	"676.3"	"1282.9"	"1400.7"	"3192.8"	"3788.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43684"	"Mitotic checkpoint protein BUB3 OS=Homo sapiens OX=9606 GN=BUB3 PE=1 SV=1"	"0.000"	""	"29"	"9"	"17"	"9"	"328"	"37.1"	"6.84"	"3837.91"	"31.81"	"9"	"8"	"cell cycle OR cell proliferation;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00400"	"9184"	"ENSG00000154473"	"BUB3"	"A6NJ42; B2R6E7; D3DRE9; hsa:9184; O43684; O43685"	"Cell cycle; Regulation of sister chromatid separation at the metaphase-anaphase transition"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of mitotic proteins; APC-Cdc20 mediated degradation of Nek2A"	"12"	"0"	"1041.4"	"838.5"	"988.0"	"912.6"	"854.7"	"923.7"	"1214.2"	"1848.8"	"1757.6"	"3655.0"	"4888.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15185"	"Prostaglandin E synthase 3 OS=Homo sapiens OX=9606 GN=PTGES3 PE=1 SV=1"	"0.000"	""	"47"	"7"	"16"	"7"	"160"	"18.7"	"4.54"	"3998.76"	"31.80"	"7"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf04969"	"10728"	"ENSG00000110958"	"PTGES3"	"A8K7D0; B4DHP2; B4DP11; B4DP21; hsa:10728; Q15185; Q8WU70"	"Aryl hydrocarbon receptor pathway; Glucocorticoid receptor pathway; Nuclear receptors meta-pathway"	"Estrogen-dependent gene expression; Potential therapeutics for SARS; HSF1 activation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Aryl hydrocarbon receptor signalling; Synthesis of Prostaglandins (PG) and Thromboxanes (TX); Attenuation phase"	"11"	"0"	"1207.0"	"942.1"	"1058.1"	"1109.1"	"1049.9"	"948.1"	"1306.3"	"1376.5"	"1304.3"	"1471.0"	"1640.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49006"	"MARCKS-related protein OS=Homo sapiens OX=9606 GN=MARCKSL1 PE=1 SV=2"	"0.000"	""	"37"	"5"	"13"	"5"	"195"	"19.5"	"4.67"	"2420.22"	"31.79"	"4"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02063"	"65108"	"ENSG00000175130"	"MARCKSL1"	"D3DPQ0; hsa:65108; P49006; Q5TEE6; Q6NXS5"	""	""	"0"	"0"	"114.6"	"97.7"	"134.2"	"117.8"	"115.5"	"112.0"	"133.8"	"1591.3"	"1592.0"	"5232.2"	"6076.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P82970"	"High mobility group nucleosome-binding domain-containing protein 5 OS=Homo sapiens OX=9606 GN=HMGN5 PE=1 SV=1"	"0.000"	""	"23"	"5"	"12"	"5"	"282"	"31.5"	"4.55"	"2104.87"	"31.76"	"4"	"5"	"cell organization and biogenesis;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01101"	"79366"	"ENSG00000198157"	"HMGN5"	"hsa:79366; P82970; Q5JSL1"	""	""	"0"	"0"	"80.0"	"49.9"	"103.4"	"88.8"	"80.3"	"76.9"	"96.5"	"934.1"	"891.0"	"4474.6"	"4244.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96PK6"	"RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2"	"0.000"	""	"18"	"11"	"20"	"11"	"669"	"69.4"	"9.67"	"3756.61"	"31.65"	"10"	"10"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00076"	"100526737; 10432"	"ENSG00000239306"	"RBM14"	"B0LM41; B3KMN4; D6RGD8; hsa:100526737; hsa:10432; O75932; Q2PYN1; Q53GV1; Q68DQ9; Q96PK5; Q96PK6"	"Ciliary landscape"	"RUNX2 regulates bone development"	"2"	"0"	"1786.5"	"1683.0"	"1628.4"	"1551.2"	"1586.0"	"1569.0"	"2114.3"	"2552.5"	"2367.0"	"4047.3"	"5821.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15344"	"E3 ubiquitin-protein ligase Midline-1 OS=Homo sapiens OX=9606 GN=MID1 PE=1 SV=1"	"0.000"	""	"16"	"9"	"16"	"9"	"667"	"75.2"	"6.80"	"2809.88"	"31.64"	"7"	"7"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00041, Pf00622, Pf00643, Pf13445, Pf13765, Pf18568"	"4281"	"ENSG00000101871"	"MID1"	"B2RCG2; hsa:4281; O15344; O75361; Q9BZX5"	""	"Interferon gamma signaling"	"1"	"0"	"419.4"	"282.8"	"441.2"	"445.7"	"424.8"	"537.0"	"838.6"	"2056.5"	"2056.0"	"4154.1"	"4388.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P26373"	"60S ribosomal protein L13 OS=Homo sapiens OX=9606 GN=RPL13 PE=1 SV=4"	"0.000"	""	"31"	"8"	"18"	"8"	"211"	"24.2"	"11.65"	"2842.36"	"31.54"	"6"	"8"	"protein metabolism;other metabolic processes;developmental processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01294"	"6137"	"ENSG00000167526"	"RPL13"	"B4DLX3; F5H1S2; hsa:6137; P26373; Q3KQT8; Q567Q8; Q9BPX0"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"1774.3"	"1560.5"	"1722.0"	"1629.0"	"1637.1"	"1719.6"	"2134.7"	"2739.1"	"2449.3"	"5012.4"	"7444.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VTR2"	"E3 ubiquitin-protein ligase BRE1A OS=Homo sapiens OX=9606 GN=RNF20 PE=1 SV=2"	"0.000"	""	"9"	"8"	"17"	"6"	"975"	"113.6"	"5.94"	"3651.73"	"31.47"	"8"	"7"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00097"	"56254"	"ENSG00000155827"	"RNF20"	"A7MCT5; hsa:56254; Q2TB34; Q5VTR2; Q69YL5; Q6P527; Q8N3J4; Q96JD3; Q9H9Y7; Q9HA51; Q9NUR4; Q9NWQ3; Q9NX83"	"ATM signaling in development and disease"	"E3 ubiquitin ligases ubiquitinate target proteins; RHOBTB1 GTPase cycle"	"3"	"2"	"424.7"	"328.8"	"478.7"	"413.0"	"440.9"	"371.5"	"512.9"	"1228.2"	"1277.5"	"2630.3"	"3614.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75521"	"Enoyl-CoA delta isomerase 2, mitochondrial OS=Homo sapiens OX=9606 GN=ECI2 PE=1 SV=4"	"0.000"	""	"21"	"5"	"9"	"5"	"394"	"43.6"	"9.00"	"1400.36"	"31.44"	"3"	"5"	"other metabolic processes"	"cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00378, Pf00887"	"10455"	"ENSG00000198721"	"ECI2"	"hsa:10455; O75521; Q5JYK5; Q5JYK7; Q7L124; Q8N0X0; Q9BUE9; Q9H0T9; Q9NQH1; Q9NYH7; Q9UN55"	""	""	"0"	"0"	"270.4"	"212.3"	"262.6"	"228.8"	"254.8"	"276.6"	"311.7"	"814.2"	"848.2"	"2997.7"	"4423.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62701"	"40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2"	"0.000"	""	"36"	"12"	"21"	"12"	"263"	"29.6"	"10.15"	"3308.32"	"31.32"	"10"	"11"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00467, Pf00900, Pf01479, Pf08071, Pf16121"	"6191"	"ENSG00000198034"	"RPS4X"	"hsa:6191; P12631; P12750; P27576; P55831; P62701; Q14727; Q6IPY4"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"1699.1"	"1318.8"	"1627.2"	"1462.3"	"1525.5"	"1545.0"	"2103.1"	"2923.1"	"2794.4"	"6393.7"	"9850.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P83731"	"60S ribosomal protein L24 OS=Homo sapiens OX=9606 GN=RPL24 PE=1 SV=1"	"0.000"	""	"42"	"8"	"21"	"8"	"157"	"17.8"	"11.25"	"4392.99"	"31.28"	"8"	"6"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01246"	"6152"	"ENSG00000114391"	"RPL24"	"B2R4Y3; hsa:6152; P38663; P83731; Q6IBS3"	"Cytoplasmic ribosomal proteins"	"Major pathway of rRNA processing in the nucleolus and cytosol; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"1557.3"	"1299.9"	"1500.8"	"1347.6"	"1336.1"	"1450.9"	"1940.5"	"2633.2"	"2545.8"	"5229.1"	"8322.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P28340"	"DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2"	"0.000"	""	"10"	"9"	"17"	"9"	"1107"	"123.6"	"7.03"	"3827.50"	"31.23"	"8"	"8"	"DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00136, Pf03104, Pf14260"	"5424"	"ENSG00000062822"	"POLD1"	"hsa:5424; P28340; Q8NER3; Q96H98"	"Homologous recombination; Pyrimidine metabolism; DNA replication; Base excision repair; Nucleotide excision repair; DNA repair pathways, full network; Progeria-associated lipodystrophy; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Cytosolic iron-sulfur cluster assembly; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Polymerase switching on the C-strand of the telomere; Polymerase switching; Removal of the Flap Intermediate; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"27"	"0"	"264.5"	"220.6"	"296.1"	"287.7"	"250.7"	"218.7"	"328.2"	"574.7"	"619.3"	"1334.7"	"2005.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14152"	"Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1"	"0.000"	""	"7"	"10"	"16"	"10"	"1382"	"166.5"	"6.79"	"2375.33"	"31.17"	"7"	"9"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;translational apparatus;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf01399"	"8661"	"ENSG00000107581"	"EIF3A"	"B1AMV5; B4DYS1; F5H335; hsa:8661; O00653; Q14152; Q15778"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"8"	"0"	"739.2"	"609.3"	"718.9"	"680.6"	"676.5"	"625.1"	"786.8"	"1112.1"	"1087.2"	"2318.8"	"6454.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14625"	"Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1"	"0.000"	""	"16"	"10"	"15"	"10"	"803"	"92.4"	"4.84"	"2245.36"	"31.13"	"6"	"9"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00183, Pf02518"	"7184"	"ENSG00000166598"	"HSP90B1"	"hsa:7184; P14625; Q96A97"	"Photodynamic therapy-induced unfolded protein response; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Prion disease pathway; PI3K-Akt signaling pathway; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Interleukin-4 and Interleukin-13 signaling; Trafficking and processing of endosomal TLR; Scavenging by Class A Receptors; ATF6 (ATF6-alpha) activates chaperone genes"	"11"	"0"	"738.4"	"610.2"	"740.5"	"703.1"	"664.7"	"687.6"	"882.1"	"1301.8"	"1214.1"	"2765.3"	"5115.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q10567"	"AP-1 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP1B1 PE=1 SV=2"	"0.000"	""	"11"	"9"	"18"	"2"	"949"	"104.6"	"5.06"	"3157.33"	"31.01"	"8"	"8"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"57.3"	"32.0"	"56.2"	"52.9"	"45.4"	"64.4"	"108.7"	"279.0"	"230.0"	"526.5"	"834.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P39687"	"Acidic leucine-rich nuclear phosphoprotein 32 family member A OS=Homo sapiens OX=9606 GN=ANP32A PE=1 SV=1"	"0.000"	""	"31"	"9"	"16"	"7"	"249"	"28.6"	"4.09"	"2807.15"	"31.01"	"8"	"7"	"transport;signal transduction;other biological processes"	"ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf14580"	"8125"	"ENSG00000140350"	"ANP32A"	"B2R6T4; hsa:8125; P39687; Q53FK4; Q5J8L8; Q7M4N6"	"IL-18 signaling pathway"	"HuR (ELAVL1) binds and stabilizes mRNA"	"2"	"2"	"1284.0"	"1122.1"	"1273.1"	"1111.9"	"1025.7"	"1139.9"	"1592.5"	"2037.0"	"1815.4"	"2945.6"	"3751.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2W2"	"WW domain-binding protein 11 OS=Homo sapiens OX=9606 GN=WBP11 PE=1 SV=1"	"0.000"	""	"13"	"6"	"12"	"6"	"641"	"70.0"	"8.38"	"2047.96"	"31.00"	"5"	"6"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09429"	"51729"	"ENSG00000084463"	"WBP11"	"hsa:51729; Q96AY8; Q9Y2W2"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"474.8"	"436.5"	"450.8"	"429.3"	"454.0"	"433.7"	"597.4"	"879.1"	"811.8"	"1522.4"	"1839.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13242"	"Serine/arginine-rich splicing factor 9 OS=Homo sapiens OX=9606 GN=SRSF9 PE=1 SV=1"	"0.000"	""	"38"	"10"	"21"	"9"	"221"	"25.5"	"8.65"	"3682.73"	"30.94"	"9"	"9"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00076"	"8683"	"ENSG00000111786"	"SRSF9"	"hsa:8683; Q13242; Q52LD1"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript"	"6"	"0"	"1261.7"	"1141.3"	"1101.1"	"1053.8"	"1050.5"	"986.6"	"1349.0"	"1625.2"	"1427.3"	"2300.2"	"3366.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P34932"	"Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4"	"0.000"	""	"18"	"13"	"21"	"10"	"840"	"94.3"	"5.19"	"4767.19"	"30.91"	"12"	"8"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport"	"non-structural extracellular;cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf00012"	"3308"	"ENSG00000170606"	"HSPA4"	"hsa:3308; O95756; P34932; Q2TAL4; Q9BUK9"	"Parkin-ubiquitin proteasomal system pathway"	"Regulation of HSF1-mediated heat shock response"	"2"	"2"	"1350.5"	"1035.0"	"1325.3"	"1258.9"	"1155.4"	"1279.9"	"1566.5"	"2188.3"	"1987.3"	"3570.7"	"5473.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43660"	"Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1"	"0.000"	""	"18"	"7"	"14"	"7"	"514"	"57.2"	"9.17"	"3120.79"	"30.89"	"6"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;nucleus;other cell component"	""	"Pf00400"	"5356"	"ENSG00000171566"	"PLRG1"	"B3KMK4; hsa:5356; O43660; Q3KQY5; Q8WUD8"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"362.3"	"295.4"	"423.4"	"389.7"	"407.2"	"381.8"	"479.2"	"1022.2"	"1041.8"	"2706.3"	"3536.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P16104"	"Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2"	"0.000"	""	"32"	"4"	"16"	"1"	"143"	"15.1"	"10.74"	"2521.77"	"30.89"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125, Pf16211"	"3014"	"ENSG00000188486"	"H2AX"	"hsa:3014; P16104; Q4ZGJ7; Q6IAS5"	"miRNA regulation of DNA damage response; miRNAs involved in DNA damage response; Proteasome degradation; ATM signaling in development and disease ; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; DNA repair pathways, full network; 5q35 copy number variation; DNA damage response"	"RUNX1 regulates transcription of genes involved in differentiation of HSCs; RMTs methylate histone arginines; Assembly of the ORC complex at the origin of replication; Amyloid fiber formation; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Oxidative Stress Induced Senescence; Senescence-Associated Secretory Phenotype (SASP); Processing of DNA double-strand break ends; Meiotic synapsis; Transcriptional regulation by small RNAs; Deposition of new CENPA-containing nucleosomes at the centromere; B-WICH complex positively regulates rRNA expression; Formation of the beta-catenin:TCF transactivating complex; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Pre-NOTCH Transcription and Translation; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; G2/M DNA damage checkpoint; RNA Polymerase I Promoter Escape; Meiotic recombination; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Packaging Of Telomere Ends; Condensation of Prophase Chromosomes; DNA Damage/Telomere Stress Induced Senescence; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; Nonhomologous End-Joining (NHEJ); RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis"	"46"	"3"	"1135.1"	"742.3"	"1320.0"	"1110.8"	"1022.4"	"1119.5"	"1526.7"	"1848.0"	"1784.5"	"3295.3"	"4259.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q07666"	"KH domain-containing, RNA-binding, signal transduction-associated protein 1 OS=Homo sapiens OX=9606 GN=KHDRBS1 PE=1 SV=1"	"0.000"	""	"20"	"8"	"17"	"8"	"443"	"48.2"	"8.66"	"3295.22"	"30.83"	"7"	"7"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf16274, Pf16568"	"10657"	"ENSG00000121774"	"KHDRBS1"	"D3DPP3; hsa:10657; Q07666; Q6PJX7; Q8NB97; Q99760"	"Leptin signaling pathway; Primary ovarian insufficiency"	"PTK6 Regulates Proteins Involved in RNA Processing"	"3"	"0"	"1470.0"	"1482.4"	"1397.9"	"1249.0"	"1247.2"	"1335.5"	"1738.1"	"2241.8"	"1918.2"	"3195.9"	"4804.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4Z0"	"U6 snRNA-associated Sm-like protein LSm4 OS=Homo sapiens OX=9606 GN=LSM4 PE=1 SV=1"	"0.000"	""	"28"	"6"	"18"	"6"	"139"	"15.3"	"9.99"	"4036.17"	"30.63"	"6"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01423"	"25804"	"ENSG00000130520"	"LSM4"	"hsa:25804; Q9Y4Z0"	"Ciliary landscape"	"mRNA Splicing - Major Pathway; mRNA decay by 5' to 3' exoribonuclease"	"3"	"0"	"478.5"	"404.2"	"521.1"	"498.5"	"471.9"	"464.6"	"563.6"	"915.8"	"896.2"	"1869.0"	"3488.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92747"	"Actin-related protein 2/3 complex subunit 1A OS=Homo sapiens OX=9606 GN=ARPC1A PE=2 SV=2"	"0.000"	""	"25"	"9"	"17"	"9"	"370"	"41.5"	"8.18"	"3259.21"	"30.57"	"8"	"9"	"cell organization and biogenesis"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf00400"	"10552"	"ENSG00000241685"	"ARPC1A"	"A4D276; B4DLQ7; D6W5S1; hsa:10552; Q7Z5U8; Q86WU5; Q8IXQ0; Q92747"	"Pathogenic Escherichia coli infection"	"Clathrin-mediated endocytosis; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; EPHB-mediated forward signaling"	"6"	"0"	"417.7"	"307.1"	"366.6"	"368.6"	"356.7"	"362.5"	"495.8"	"2054.9"	"2223.5"	"5404.2"	"6733.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94832"	"Unconventional myosin-Id OS=Homo sapiens OX=9606 GN=MYO1D PE=1 SV=2"	"0.000"	""	"9"	"8"	"17"	"8"	"1006"	"116.1"	"9.39"	"2871.52"	"30.54"	"7"	"8"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00063, Pf00612, Pf06017"	"4642"	"ENSG00000176658"	"MYO1D"	"A6H8V3; hsa:4642; O94832; Q8NHP9"	""	""	"0"	"0"	"384.0"	"305.5"	"400.5"	"347.7"	"369.8"	"387.6"	"526.0"	"1152.6"	"1096.4"	"2598.6"	"4077.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EP5"	"DAZ-associated protein 1 OS=Homo sapiens OX=9606 GN=DAZAP1 PE=1 SV=1"	"0.000"	""	"18"	"5"	"13"	"5"	"407"	"43.4"	"8.56"	"2426.02"	"30.48"	"4"	"5"	"cell cycle OR cell proliferation;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"26528"	"ENSG00000071626"	"DAZAP1"	"hsa:26528; Q96EP5; Q96MJ3; Q9NRR9"	""	""	"0"	"0"	"357.5"	"305.4"	"346.8"	"373.4"	"379.4"	"309.1"	"453.2"	"599.0"	"546.8"	"830.1"	"1071.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96FV9"	"THO complex subunit 1 OS=Homo sapiens OX=9606 GN=THOC1 PE=1 SV=1"	"0.000"	""	"18"	"9"	"16"	"9"	"657"	"75.6"	"4.98"	"3470.71"	"30.45"	"8"	"8"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;transport;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00531, Pf11957"	"9984"	"ENSG00000079134"	"THOC1"	"B2RBP6; hsa:9984; Q15219; Q64I72; Q64I73; Q96FV9"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"3"	"0"	"507.5"	"400.8"	"572.9"	"491.6"	"462.5"	"472.2"	"658.7"	"954.5"	"895.2"	"1702.9"	"2583.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P47813"	"Eukaryotic translation initiation factor 1A, X-chromosomal OS=Homo sapiens OX=9606 GN=EIF1AX PE=1 SV=2"	"0.000"	""	"58"	"8"	"16"	"8"	"144"	"16.5"	"5.24"	"3115.38"	"30.38"	"7"	"7"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf01176"	"1964"	"ENSG00000173674"	"EIF1AX"	"B2R5U5; hsa:1964; P47813; Q0VGC2; Q5JPS5; Q5JPS6"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition"	"8"	"0"	"79.2"	"86.4"	"97.4"	"90.3"	"93.8"	"94.8"	"111.5"	"1293.9"	"1326.3"	"5745.7"	"3189.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43795"	"Unconventional myosin-Ib OS=Homo sapiens OX=9606 GN=MYO1B PE=1 SV=3"	"0.000"	""	"7"	"6"	"15"	"5"	"1136"	"131.9"	"9.38"	"2774.23"	"30.37"	"5"	"6"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00063, Pf00612, Pf06017"	"4430"	"ENSG00000128641"	"MYO1B"	"hsa:4430; O43794; O43795; Q7Z6L5"	""	""	"0"	"0"	"270.9"	"237.4"	"302.7"	"277.4"	"262.3"	"286.7"	"403.7"	"896.8"	"874.0"	"1829.6"	"2561.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96FN4"	"Copine-2 OS=Homo sapiens OX=9606 GN=CPNE2 PE=1 SV=3"	"0.000"	""	"12"	"4"	"10"	"4"	"548"	"61.2"	"6.07"	"1944.01"	"30.30"	"3"	"4"	"other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00168, Pf07002"	"221184"	"ENSG00000140848"	"CPNE2"	"hsa:221184; Q68D19; Q719H8; Q86XP9; Q96FN4"	""	""	"0"	"0"	"46.8"	"37.0"	"69.9"	"49.0"	"52.5"	"54.1"	"78.1"	"281.0"	"280.2"	"1350.7"	"2130.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14978"	"Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2"	"0.000"	""	"14"	"10"	"21"	"10"	"699"	"73.6"	"9.47"	"3844.63"	"30.22"	"9"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05022"	"9221"	"ENSG00000166197"	"NOLC1"	"hsa:9221; Q14978; Q15030; Q5VV70; Q9BUV3"	""	""	"0"	"0"	"1330.1"	"1103.2"	"1247.9"	"1207.5"	"1279.8"	"1292.2"	"1552.5"	"2241.9"	"2169.4"	"3445.8"	"4787.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86V81"	"THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3"	"0.000"	""	"47"	"7"	"10"	"7"	"257"	"26.9"	"11.15"	"1426.59"	"30.15"	"4"	"6"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf13865"	"10189"	""	"ALYREF"	"hsa:10189; O43672; Q86V81"	""	"mRNA Splicing - Major Pathway; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"7"	"0"	"974.2"	"880.1"	"981.8"	"894.5"	"863.6"	"882.9"	"1186.8"	"1560.8"	"1283.4"	"2973.9"	"4754.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95347"	"Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2"	"0.000"	""	"10"	"11"	"20"	"11"	"1197"	"135.6"	"8.43"	"3989.10"	"30.05"	"11"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02463, Pf06470"	"10592"	"ENSG00000136824"	"SMC2"	"hsa:10592; O95347; Q6IEE0; Q9P1P2"	"Retinoblastoma gene in cancer"	"Condensation of Prophase Chromosomes; Condensation of Prometaphase Chromosomes"	"3"	"0"	"1339.9"	"1043.7"	"1245.7"	"1195.3"	"1194.0"	"1225.1"	"1517.1"	"2102.9"	"2020.5"	"3582.1"	"4195.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P24752"	"Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1"	"0.000"	""	"17"	"7"	"16"	"7"	"427"	"45.2"	"8.85"	"2267.36"	"30.04"	"6"	"7"	"other metabolic processes;stress response;developmental processes;other biological processes"	"mitochondrion;ER/Golgi"	"other molecular function"	"Pf00108, Pf02803"	"38"	"ENSG00000075239"	"ACAT1"	"B2R6H1; G3XAB4; hsa:38; P24752; Q96FG8"	"Fatty acid beta-oxidation; Tryptophan metabolism; SARS-CoV-2 and COVID-19 pathway"	"Branched-chain amino acid catabolism; Utilization of Ketone Bodies; Synthesis of Ketone Bodies"	"6"	"0"	"526.1"	"399.1"	"581.1"	"534.2"	"513.9"	"506.5"	"666.6"	"1522.2"	"1441.1"	"4746.4"	"7189.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13185"	"Chromobox protein homolog 3 OS=Homo sapiens OX=9606 GN=CBX3 PE=1 SV=4"	"0.000"	""	"32"	"5"	"13"	"3"	"183"	"20.8"	"5.33"	"2274.27"	"29.84"	"4"	"4"	"cell organization and biogenesis;stress response;other biological processes"	"other membranes;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00385, Pf01393"	"11335"	"ENSG00000122565"	"CBX3"	"hsa:11335; Q13185; Q96CD7; Q99409; Q9BVS3; Q9P0Z6"	"Exercise-induced circadian regulation; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; NIPBL role in DNA damage - Cornelia de Lange syndrome"	"RNA Polymerase I Promoter Escape; Transcriptional Regulation by E2F6; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"	"6"	"2"	"288.0"	"279.1"	"324.4"	"316.4"	"294.8"	"277.7"	"340.3"	"533.5"	"556.2"	"1387.2"	"3733.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NFH4"	"Nucleoporin Nup37 OS=Homo sapiens OX=9606 GN=NUP37 PE=1 SV=1"	"0.000"	""	"25"	"6"	"13"	"6"	"326"	"36.7"	"5.92"	"3345.59"	"29.84"	"6"	"5"	"cell cycle OR cell proliferation;transport;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf00400"	"79023"	"ENSG00000075188"	"NUP37"	"hsa:79023; Q8NFH4; Q9H644"	""	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; ISG15 antiviral mechanism; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Vpr-mediated nuclear import of PICs; Transport of Mature mRNA derived from an Intron-Containing Transcript; tRNA processing in the nucleus; HCMV Late Events; HCMV Early Events; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); SARS-CoV-2 activates/modulates innate and adaptive immune responses; Postmitotic nuclear pore complex (NPC) reformation"	"35"	"0"	"820.1"	"583.0"	"720.5"	"715.8"	"614.5"	"753.3"	"1044.5"	"1783.0"	"1737.2"	"3329.7"	"4224.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q2NL82"	"Pre-rRNA-processing protein TSR1 homolog OS=Homo sapiens OX=9606 GN=TSR1 PE=1 SV=1"	"0.000"	""	"14"	"11"	"19"	"11"	"804"	"91.8"	"7.42"	"3452.35"	"29.82"	"10"	"9"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04950, Pf08142"	"55720"	"ENSG00000167721"	"TSR1"	"hsa:55720; Q2NL82; Q8WUY5; Q9NVT0; Q9P2E6"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"410.2"	"348.1"	"454.9"	"383.7"	"428.5"	"500.2"	"728.0"	"2018.4"	"1913.9"	"4439.1"	"4175.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P39748"	"Flap endonuclease 1 OS=Homo sapiens OX=9606 GN=FEN1 PE=1 SV=1"	"0.000"	""	"25"	"9"	"18"	"9"	"380"	"42.6"	"8.62"	"3855.37"	"29.81"	"9"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00752, Pf00867"	"2237"	"ENSG00000168496"	"FEN1"	"hsa:2237; P39748"	"Base excision repair; DNA repair pathways, full network"	"HDR through MMEJ (alt-NHEJ); Early Phase of HIV Life Cycle; POLB-Dependent Long Patch Base Excision Repair; PCNA-Dependent Long Patch Base Excision Repair; Removal of the Flap Intermediate; Removal of the Flap Intermediate from the C-strand"	"8"	"0"	"1886.3"	"1375.3"	"1733.1"	"1625.5"	"1501.2"	"1603.7"	"2170.1"	"4240.9"	"4000.5"	"6629.2"	"6384.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P40222"	"Alpha-taxilin OS=Homo sapiens OX=9606 GN=TXLNA PE=1 SV=3"	"0.000"	""	"22"	"10"	"18"	"9"	"546"	"61.9"	"6.52"	"3603.14"	"29.74"	"9"	"9"	"transport;other biological processes"	"non-structural extracellular;cytosol;other cell component"	"other molecular function"	"Pf09728"	"200081"	"ENSG00000084652"	"TXLNA"	"D3DPP6; hsa:200081; P40222; Q5TFJ6; Q66K62; Q86T54; Q86T85; Q86T86; Q86Y86; Q86YW3; Q8N2Y3"	""	"Other interleukin signaling"	"1"	"1"	"753.4"	"605.3"	"764.0"	"648.4"	"685.3"	"647.8"	"927.0"	"1861.3"	"1711.8"	"3304.3"	"3774.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q32MZ4"	"Leucine-rich repeat flightless-interacting protein 1 OS=Homo sapiens OX=9606 GN=LRRFIP1 PE=1 SV=2"	"0.000"	""	"12"	"8"	"16"	"8"	"808"	"89.2"	"4.65"	"3053.36"	"29.72"	"8"	"8"	"other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09738"	"9208"	"ENSG00000124831"	"LRRFIP1"	"E9PGZ2; hsa:9208; O75766; O75799; Q32MZ4; Q32MZ5; Q53T49; Q6PKG2; Q9Y607"	"IL-18 signaling pathway; 2q37 copy number variation syndrome"	"Signaling by cytosolic FGFR1 fusion mutants; Signaling by FGFR1 in disease; LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production"	"5"	"0"	"241.2"	"192.1"	"252.7"	"245.9"	"235.5"	"246.8"	"298.7"	"862.7"	"862.6"	"2576.9"	"3427.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15075"	"Early endosome antigen 1 OS=Homo sapiens OX=9606 GN=EEA1 PE=1 SV=2"	"0.000"	""	"7"	"8"	"14"	"8"	"1411"	"162.4"	"5.68"	"2899.33"	"29.68"	"7"	"7"	"cell-cell signaling;cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01363"	"8411"	"ENSG00000102189"	"EEA1"	"hsa:8411; Q14221; Q15075"	"VEGFA-VEGFR2 signaling"	"Toll Like Receptor 9 (TLR9) Cascade"	"2"	"0"	"153.6"	"116.4"	"157.1"	"151.7"	"176.9"	"145.2"	"180.2"	"747.9"	"753.8"	"1980.8"	"2973.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96CT7"	"Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1"	"0.000"	""	"41"	"7"	"15"	"7"	"223"	"25.8"	"9.54"	"2852.13"	"29.60"	"6"	"7"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf06244"	"115098"	"ENSG00000007080"	"CCDC124"	"hsa:115098; Q96CT7"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"1126.0"	"948.8"	"1009.1"	"1023.9"	"1035.2"	"1065.9"	"1309.1"	"1767.1"	"1646.9"	"2500.1"	"2508.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63244"	"Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3"	"0.000"	""	"24"	"7"	"14"	"7"	"317"	"35.1"	"7.69"	"2429.35"	"29.47"	"5"	"7"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;cytosol;mitochondrion;translational apparatus;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;translation activity;other molecular function"	"Pf00400"	"10399"	"ENSG00000204628"	"RACK1"	"B3KTJ0; D3DWS0; hsa:10399; P25388; P63244; P99049; Q53HU2; Q5J8M6; Q5VLR4; Q6FH47"	"Androgen receptor signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; VEGFA-VEGFR2 signaling; Measles virus infection; Angiotensin II receptor type 1 pathway; TROP2 regulatory signaling; Interferon type I signaling pathways"	"Regulation of TNFR1 signaling; TNFR1-induced NF-kappa-B signaling pathway; TNFR1-mediated ceramide production"	"10"	"0"	"396.0"	"269.2"	"467.5"	"352.5"	"325.2"	"379.3"	"520.3"	"1185.6"	"1236.5"	"3165.5"	"7619.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99613"	"Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1"	"0.000"	""	"8"	"7"	"15"	"7"	"913"	"105.3"	"5.68"	"3009.84"	"29.41"	"5"	"6"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf01399, Pf05470"	"8663"	"ENSG00000184110"	"EIF3C"	"A8K7Z0; B2RXG3; B4E1D5; H3BRV0; hsa:8663; O00215; Q99613; Q9BW98"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"8"	"0"	"740.4"	"569.2"	"761.0"	"695.6"	"626.6"	"686.4"	"827.2"	"1066.0"	"952.9"	"1850.5"	"5304.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14126"	"Desmoglein-2 OS=Homo sapiens OX=9606 GN=DSG2 PE=1 SV=2"	"0.000"	""	"7"	"6"	"14"	"6"	"1118"	"122.2"	"5.24"	"3157.82"	"29.37"	"6"	"6"	"cell adhesion;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00028"	"1829"	"ENSG00000046604"	"DSG2"	"hsa:1829; Q14126; Q4KKU6"	"Arrhythmogenic right ventricular cardiomyopathy; GDNF signaling"	"Formation of the cornified envelope; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; Apoptotic cleavage of cell adhesion  proteins"	"8"	"0"	"530.9"	"399.2"	"515.1"	"446.6"	"462.9"	"445.6"	"555.6"	"1072.7"	"1001.6"	"2263.6"	"3263.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43143"	"Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2"	"0.000"	""	"11"	"7"	"15"	"7"	"795"	"90.9"	"7.46"	"3103.38"	"29.32"	"7"	"7"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"1665"	"ENSG00000109606"	"DHX15"	"hsa:1665; O43143; Q9NQT7"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"309.9"	"189.6"	"367.1"	"300.4"	"321.6"	"288.3"	"455.2"	"883.4"	"856.1"	"2443.8"	"4093.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94842"	"TOX high mobility group box family member 4 OS=Homo sapiens OX=9606 GN=TOX4 PE=1 SV=1"	"0.000"	""	"15"	"8"	"16"	"8"	"621"	"66.2"	"5.06"	"3028.54"	"29.27"	"8"	"8"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00505"	"9878"	"ENSG00000092203"	"TOX4"	"B4DPY8; B4DSM0; E7EV69; hsa:9878; O94842"	""	""	"0"	"0"	"547.2"	"378.8"	"460.2"	"470.1"	"444.8"	"448.8"	"551.7"	"1035.4"	"982.8"	"2304.9"	"3066.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6PI48"	"Aspartate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=DARS2 PE=1 SV=1"	"0.000"	""	"11"	"6"	"14"	"6"	"645"	"73.5"	"8.02"	"2733.11"	"29.26"	"6"	"6"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00152, Pf01336, Pf02938"	"55157"	"ENSG00000117593"	"DARS2"	"hsa:55157; Q6PI48"	""	"Mitochondrial tRNA aminoacylation"	"1"	"0"	"368.4"	"298.2"	"401.9"	"370.5"	"338.9"	"316.8"	"488.4"	"852.8"	"825.1"	"2041.0"	"2608.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P15880"	"40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2"	"0.000"	""	"33"	"9"	"18"	"9"	"293"	"31.3"	"10.24"	"3746.05"	"29.22"	"8"	"8"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00333, Pf03719"	"6187"	"ENSG00000140988"	"RPS2"	"B2R5G0; D3DU82; hsa:6187; P15880; Q3MIB1"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; RMTs methylate histone arginines; Protein methylation; Peptide chain elongation; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"22"	"0"	"902.1"	"845.1"	"927.9"	"843.9"	"777.4"	"807.5"	"1224.7"	"2254.6"	"2242.0"	"5655.3"	"8559.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16576"	"Histone-binding protein RBBP7 OS=Homo sapiens OX=9606 GN=RBBP7 PE=1 SV=1"	"0.000"	""	"13"	"7"	"18"	"1"	"425"	"47.8"	"5.05"	"3416.87"	"29.16"	"7"	"7"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400, Pf12265"	"5931"	"ENSG00000102054"	"RBBP7"	"hsa:5931; Q16576; Q5JP00"	"Retinoblastoma gene in cancer; Interactome of polycomb repressive complex 2 (PRC2) ; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"HCMV Early Events; Deposition of new CENPA-containing nucleosomes at the centromere; Neddylation; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Potential therapeutics for SARS; Oxidative Stress Induced Senescence; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6; HDACs deacetylate histones; RMTs methylate histone arginines; PKMTs methylate histone lysines; HATs acetylate histones; RNA Polymerase I Transcription Initiation; PRC2 methylates histones and DNA; Defective pyroptosis; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of TP53 Activity through Acetylation"	"20"	"0"	"230.0"	"276.5"	"160.0"	"159.8"	"169.0"	"198.2"	"261.9"	"346.1"	"281.7"	"638.0"	"1030.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14562"	"ATP-dependent RNA helicase DHX8 OS=Homo sapiens OX=9606 GN=DHX8 PE=1 SV=1"	"0.000"	""	"9"	"8"	"14"	"8"	"1220"	"139.2"	"8.32"	"2001.30"	"29.15"	"6"	"8"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf00271, Pf00575, Pf04408, Pf07717"	"1659"	"ENSG00000067596"	"DHX8"	"hsa:1659; Q14562"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"184.6"	"120.6"	"200.5"	"185.6"	"177.3"	"177.4"	"224.3"	"403.4"	"398.6"	"1076.9"	"1779.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q08170"	"Serine/arginine-rich splicing factor 4 OS=Homo sapiens OX=9606 GN=SRSF4 PE=1 SV=2"	"0.000"	""	"16"	"8"	"19"	"4"	"494"	"56.6"	"11.52"	"3197.84"	"29.10"	"7"	"8"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076"	"6429"	"ENSG00000116350"	"SRSF4"	"hsa:6429; Q08170; Q5VXP1; Q9BUA4; Q9UEB5"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript"	"6"	"0"	"845.2"	"645.5"	"815.0"	"741.9"	"733.0"	"727.2"	"946.5"	"928.3"	"918.9"	"1333.1"	"2258.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15424"	"Scaffold attachment factor B1 OS=Homo sapiens OX=9606 GN=SAFB PE=1 SV=4"	"0.000"	""	"12"	"9"	"20"	"5"	"915"	"102.6"	"5.47"	"3543.41"	"28.98"	"8"	"7"	"cell organization and biogenesis;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf02037"	"6294"	"ENSG00000160633"	"SAFB"	"A0AV56; B7Z5B6; B7ZLP6; F5H0H3; hsa:6294; O60406; Q15424; Q59HH8"	"Interleukin-1 (IL-1) structural pathway"	"SUMOylation of transcription cofactors"	"2"	"4"	"1558.2"	"1330.8"	"1621.9"	"1436.1"	"1411.9"	"1356.0"	"1744.2"	"2037.8"	"1761.5"	"3896.0"	"7203.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P33993"	"DNA replication licensing factor MCM7 OS=Homo sapiens OX=9606 GN=MCM7 PE=1 SV=4"	"0.000"	""	"16"	"10"	"17"	"10"	"719"	"81.3"	"6.46"	"4688.69"	"28.98"	"10"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf14551, Pf17207, Pf17855"	"4176"	"ENSG00000166508"	"MCM7"	"A4D2A1; A4D2A2; E9PGN9; hsa:4176; P33993; Q15076; Q96D34; Q96GL1"	"miRNA regulation of DNA damage response; Cell cycle; Retinoblastoma gene in cancer; Ciliary landscape; G1 to S cell cycle control; DNA replication"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"12"	"0"	"606.0"	"448.8"	"566.4"	"545.6"	"467.8"	"498.1"	"619.6"	"1075.2"	"1049.3"	"2501.8"	"5742.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49454"	"Centromere protein F OS=Homo sapiens OX=9606 GN=CENPF PE=1 SV=3"	"0.000"	""	"4"	"11"	"19"	"10"	"3114"	"357.3"	"5.10"	"3346.50"	"28.91"	"9"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf10473, Pf10481, Pf10490"	"1063"	"ENSG00000117724"	"CENPF"	"hsa:1063; P49454; Q13171; Q13246; Q5VVM7"	"Gastric cancer network 1; Ciliopathies"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Polo-like kinase mediated events"	"9"	"0"	"301.6"	"243.4"	"375.1"	"277.7"	"302.7"	"298.3"	"360.8"	"555.1"	"595.7"	"1140.4"	"1541.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60256"	"Phosphoribosyl pyrophosphate synthase-associated protein 2 OS=Homo sapiens OX=9606 GN=PRPSAP2 PE=1 SV=1"	"0.000"	""	"24"	"9"	"19"	"9"	"369"	"40.9"	"7.44"	"3111.79"	"28.91"	"9"	"8"	"other metabolic processes;developmental processes"	"other cell component"	"enzyme regulator activity;other molecular function"	"Pf13793, Pf14572"	"5636"	"ENSG00000141127"	"PRPSAP2"	"B4E1M8; B4E329; B7ZKZ1; E7EMY2; hsa:5636; O60256; Q6IAS2"	""	""	"0"	"0"	"292.0"	"208.1"	"311.7"	"307.3"	"276.4"	"318.2"	"431.4"	"1353.8"	"1428.5"	"3633.5"	"5243.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3Y2"	"Chromatin target of PRMT1 protein OS=Homo sapiens OX=9606 GN=CHTOP PE=1 SV=2"	"0.000"	""	"31"	"6"	"19"	"6"	"248"	"26.4"	"12.23"	"4069.83"	"28.90"	"6"	"5"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf13865"	"26097"	"ENSG00000160679"	"CHTOP"	"D3DV55; hsa:26097; Q0VAQ8; Q2VPI9; Q5T7Y8; Q5T7Y9; Q5T7Z0; Q6NSM4; Q6PB28; Q8WYT9; Q9BUC5; Q9H034; Q9H2L0; Q9Y3Y2"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"3"	"0"	"1017.5"	"716.6"	"1057.4"	"945.6"	"859.4"	"992.0"	"1258.7"	"1676.9"	"1558.9"	"3124.9"	"5021.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96I25"	"Splicing factor 45 OS=Homo sapiens OX=9606 GN=RBM17 PE=1 SV=1"	"0.000"	""	"20"	"8"	"18"	"7"	"401"	"44.9"	"5.97"	"3600.76"	"28.85"	"8"	"6"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf01585"	"84991"	"ENSG00000134453"	"RBM17"	"hsa:84991; Q96GY6; Q96I25"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"1"	"466.0"	"393.5"	"489.5"	"466.0"	"455.4"	"472.2"	"579.0"	"858.5"	"800.3"	"3142.4"	"5425.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NYL9"	"Tropomodulin-3 OS=Homo sapiens OX=9606 GN=TMOD3 PE=1 SV=1"	"0.000"	""	"21"	"6"	"12"	"6"	"352"	"39.6"	"5.19"	"3025.55"	"28.81"	"6"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton"	"cytoskeletal activity"	"Pf03250"	"29766"	"ENSG00000138594"	"TMOD3"	"B2R6G7; hsa:29766; Q9NT43; Q9NYL9; Q9NZR0"	"VEGFA-VEGFR2 signaling"	"Striated Muscle Contraction; RND3 GTPase cycle; RHOBTB2 GTPase cycle"	"4"	"0"	"520.3"	"366.8"	"468.3"	"458.6"	"446.9"	"411.8"	"534.6"	"807.0"	"814.7"	"1567.7"	"2259.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16836"	"Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=HADH PE=1 SV=3"	"0.000"	""	"31"	"9"	"17"	"9"	"314"	"34.3"	"8.85"	"2783.27"	"28.73"	"8"	"7"	"other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00725, Pf02737"	"3033"	"ENSG00000138796"	"HADH"	"hsa:3033; J3KQ17; O00324; O00397; O00753; Q16836; Q4W5B4"	"Fatty acid beta-oxidation; Fatty acid biosynthesis; Mitochondrial long chain fatty acid beta-oxidation; Amino acid metabolism; IL-18 signaling pathway; Mitochondrial fatty acid oxidation disorders"	"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA; Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of butanoyl-CoA to acetyl-CoA; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA"	"11"	"0"	"824.6"	"645.5"	"772.6"	"779.9"	"757.9"	"728.9"	"947.5"	"2277.2"	"2564.9"	"7098.7"	"9233.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23588"	"Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2"	"0.000"	""	"15"	"7"	"14"	"7"	"611"	"69.1"	"5.73"	"2941.65"	"28.68"	"6"	"6"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus"	"nucleic acid binding activity"	"Pf00076"	"1975"	"ENSG00000063046"	"EIF4B"	"B4DS13; hsa:1975; P23588; Q4G0E3; Q53HQ2; Q6GPH5; Q6IB46; Q8WYK5"	"Translation factors; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Translation inhibitors in chronically activated PDGFRA cells; Perturbations to host-cell autophagy, induced by SARS-CoV-2 proteins; Pleural mesothelioma; Interferon type I signaling pathways"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Deadenylation of mRNA; mTORC1-mediated signalling"	"14"	"0"	"313.3"	"251.9"	"312.5"	"290.7"	"305.6"	"294.1"	"349.7"	"1041.3"	"1042.6"	"3414.4"	"4444.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IY18"	"Structural maintenance of chromosomes protein 5 OS=Homo sapiens OX=9606 GN=SMC5 PE=1 SV=2"	"0.000"	""	"9"	"9"	"16"	"9"	"1101"	"128.7"	"8.38"	"2893.02"	"28.67"	"7"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02463"	"23137"	"ENSG00000198887"	"SMC5"	"A6NM81; hsa:23137; O60335; Q05D92; Q5VZ60; Q8IY18; Q96SB9"	""	"SUMOylation of DNA damage response and repair proteins"	"1"	"0"	"422.4"	"355.0"	"485.1"	"417.3"	"463.7"	"442.6"	"568.5"	"930.9"	"849.5"	"1845.8"	"2270.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6UX04"	"Spliceosome-associated protein CWC27 homolog OS=Homo sapiens OX=9606 GN=CWC27 PE=1 SV=1"	"0.000"	""	"18"	"6"	"13"	"6"	"472"	"53.8"	"5.80"	"2554.60"	"28.59"	"5"	"6"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf00160"	"10283"	"ENSG00000153015"	"CWC27"	"hsa:10283; O60529; O60530; Q6UX04; Q96EM3"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"623.8"	"460.6"	"651.8"	"646.9"	"621.5"	"606.5"	"740.1"	"977.5"	"989.5"	"1699.9"	"2230.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49588"	"Alanine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=AARS1 PE=1 SV=2"	"0.000"	""	"10"	"8"	"12"	"8"	"968"	"106.7"	"5.53"	"1677.56"	"28.59"	"4"	"8"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;mitochondrion;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01411, Pf02272, Pf07973"	"16"	"ENSG00000090861"	"AARS1"	"A6NF14; B4DR45; hsa:16; P49588; Q53GV7; Q96FA0"	"IL-18 signaling pathway"	"Cytosolic tRNA aminoacylation"	"2"	"0"	"294.5"	"240.7"	"319.8"	"300.0"	"279.9"	"285.3"	"356.3"	"704.2"	"660.7"	"3051.9"	"6602.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15144"	"Actin-related protein 2/3 complex subunit 2 OS=Homo sapiens OX=9606 GN=ARPC2 PE=1 SV=1"	"0.000"	""	"36"	"8"	"15"	"8"	"300"	"34.3"	"7.36"	"2496.21"	"28.58"	"6"	"7"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity"	"Pf04045"	"10109"	"ENSG00000163466"	"ARPC2"	"hsa:10109; O15144; Q92801; Q9P1D4"	"Pathogenic Escherichia coli infection"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Clathrin-mediated endocytosis; EPHB-mediated forward signaling"	"6"	"0"	"315.1"	"207.1"	"288.6"	"250.9"	"266.1"	"289.6"	"353.6"	"1292.9"	"1329.6"	"3926.4"	"5060.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15291"	"Retinoblastoma-binding protein 5 OS=Homo sapiens OX=9606 GN=RBBP5 PE=1 SV=2"	"0.000"	""	"14"	"5"	"11"	"5"	"538"	"59.1"	"5.10"	"1307.94"	"28.47"	"3"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00400"	"5929"	"ENSG00000117222"	"RBBP5"	"A8K272; hsa:5929; Q15291; Q7Z6D8; Q8NDZ7"	"Kleefstra syndrome"	"Neddylation; Formation of WDR5-containing histone-modifying complexes; Formation of the beta-catenin:TCF transactivating complex; Deactivation of the beta-catenin transactivating complex; Activation of anterior HOX genes in hindbrain development during early embryogenesis; PKMTs methylate histone lysines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"	"8"	"0"	"139.3"	"95.2"	"150.4"	"143.6"	"138.5"	"169.1"	"173.0"	"358.0"	"392.7"	"1214.0"	"1691.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14157"	"Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2"	"0.000"	""	"9"	"7"	"13"	"7"	"1087"	"114.5"	"7.11"	"2561.51"	"28.45"	"6"	"7"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	""	"Pf12478"	"9898"	"ENSG00000143569"	"UBAP2L"	"B4E0U8; hsa:9898; Q14157; Q5VU75; Q5VU76; Q9BTU3; Q9UGL2; Q9UGL3; Q9UGL4; Q9UGL5"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"764.2"	"600.8"	"710.1"	"717.9"	"676.0"	"683.9"	"893.1"	"1235.8"	"1180.3"	"2122.3"	"2575.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5JSL3"	"Dedicator of cytokinesis protein 11 OS=Homo sapiens OX=9606 GN=DOCK11 PE=1 SV=2"	"0.000"	""	"7"	"11"	"19"	"11"	"2073"	"237.5"	"7.74"	"4791.74"	"28.42"	"10"	"8"	"signal transduction;other biological processes"	"cytosol"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf06920, Pf11878, Pf14429, Pf20421, Pf20422"	"139818"	"ENSG00000147251"	"DOCK11"	"A6NMF0; hsa:139818; Q5JSL3; Q66M66; Q6ZUJ5; Q86VU8; Q96MN3"	""	"Factors involved in megakaryocyte development and platelet production; CDC42 GTPase cycle; RAC1 GTPase cycle"	"3"	"0"	"466.3"	"382.4"	"495.8"	"498.2"	"606.0"	"1862.1"	"3243.9"	"2437.5"	"1664.2"	"1257.8"	"1666.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14776"	"Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2"	"0.000"	""	"8"	"9"	"17"	"8"	"1098"	"123.8"	"8.65"	"3097.79"	"28.41"	"9"	"8"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00397, Pf01846"	"10915"	"ENSG00000113649"	"TCERG1"	"hsa:10915; O14776; Q2NKN2; Q59EA1"	""	"mRNA Splicing - Major Pathway"	"1"	"1"	"1175.6"	"892.0"	"1140.0"	"1050.7"	"1003.1"	"1080.3"	"1358.3"	"2148.6"	"1998.3"	"3679.0"	"4943.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P54819"	"Adenylate kinase 2, mitochondrial OS=Homo sapiens OX=9606 GN=AK2 PE=1 SV=2"	"0.000"	""	"38"	"8"	"13"	"8"	"239"	"26.5"	"7.81"	"2854.43"	"28.40"	"6"	"7"	"other metabolic processes"	"cytoskeleton;mitochondrion;other cell component"	"kinase activity;other molecular function"	"Pf00406, Pf05191"	"204"	"ENSG00000004455"	"AK2"	"A8K6L1; B4DHH7; B4DL64; hsa:204; P54819; Q16856; Q5EB54; Q5TIF7; Q8TCY2; Q8TCY3"	""	"Interconversion of nucleotide di- and triphosphates"	"1"	"0"	"236.9"	"156.6"	"317.1"	"279.3"	"247.4"	"265.5"	"316.4"	"708.0"	"717.0"	"2887.0"	"6259.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55209"	"Nucleosome assembly protein 1-like 1 OS=Homo sapiens OX=9606 GN=NAP1L1 PE=1 SV=1"	"0.000"	""	"20"	"6"	"15"	"5"	"391"	"45.3"	"4.46"	"2843.16"	"28.40"	"6"	"5"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00956"	"4673"	"ENSG00000187109"	"NAP1L1"	"B3KNT8; B3KV44; hsa:4673; P55209"	"VEGFA-VEGFR2 signaling; Overlap between signal transduction pathways contributing to LMNA laminopathies"	""	"2"	"1"	"375.3"	"286.6"	"358.8"	"407.7"	"358.3"	"427.1"	"515.5"	"875.0"	"830.2"	"1949.6"	"3186.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P28370"	"Probable global transcription activator SNF2L1 OS=Homo sapiens OX=9606 GN=SMARCA1 PE=1 SV=2"	"0.000"	""	"8"	"10"	"19"	"5"	"1054"	"122.5"	"8.09"	"3702.59"	"28.34"	"10"	"9"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf09110, Pf09111"	"6594"	"ENSG00000102038"	"SMARCA1"	"hsa:6594; P28370; Q5JV41; Q5JV42"	"Nuclear receptors meta-pathway; Rett syndrome causing genes"	""	"2"	"0"	"555.7"	"436.3"	"528.2"	"497.3"	"533.7"	"554.7"	"723.8"	"1210.0"	"1152.3"	"1668.3"	"1728.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14257"	"Reticulocalbin-2 OS=Homo sapiens OX=9606 GN=RCN2 PE=1 SV=1"	"0.000"	""	"33"	"5"	"9"	"5"	"317"	"36.9"	"4.40"	"2371.52"	"28.22"	"4"	"5"	""	"ER/Golgi;nucleus"	"other molecular function"	"Pf13202"	"5955"	"ENSG00000117906"	"RCN2"	"A8MTG6; F8WCY5; hsa:5955; Q14257; Q53XN8"	""	""	"0"	"0"	"673.6"	"541.6"	"507.8"	"551.1"	"515.2"	"555.9"	"697.9"	"799.8"	"788.4"	"1212.2"	"1406.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11177"	"Pyruvate dehydrogenase E1 component subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=PDHB PE=1 SV=3"	"0.000"	""	"26"	"7"	"15"	"7"	"359"	"39.2"	"6.65"	"2543.90"	"28.16"	"6"	"7"	"other metabolic processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf02779, Pf02780"	"5162"	"ENSG00000168291"	"PDHB"	"B2R7L0; B4DDD7; hsa:5162; P11177; Q6FH45; Q9BQ27; Q9UFK3"	"Metabolic reprogramming in colon cancer; Orexin receptor pathway"	"Glyoxylate metabolism and glycine degradation; Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid"	"6"	"0"	"503.7"	"407.6"	"558.3"	"460.3"	"449.2"	"522.4"	"637.9"	"881.8"	"880.5"	"1813.0"	"2527.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IX01"	"SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2"	"0.000"	""	"11"	"9"	"16"	"9"	"1082"	"120.1"	"7.28"	"3022.35"	"28.07"	"8"	"8"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf01585, Pf01805"	"10147"	"ENSG00000064607"	"SUGP2"	"C9JI71; hsa:10147; O15071; O60369; Q5JPH7; Q8IX01; Q8WUF7"	"mRNA processing"	""	"1"	"0"	"534.1"	"453.9"	"578.1"	"514.8"	"507.4"	"518.2"	"678.9"	"854.6"	"871.8"	"1617.8"	"2372.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P80303"	"Nucleobindin-2 OS=Homo sapiens OX=9606 GN=NUCB2 PE=1 SV=3"	"0.000"	""	"25"	"6"	"9"	"6"	"420"	"50.2"	"5.12"	"1552.39"	"28.04"	"3"	"6"	"signal transduction"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf13499"	"4925"	"ENSG00000070081"	"NUCB2"	"A8K642; D3DQX5; hsa:4925; P80303; Q8NFT5; V9HW75"	""	""	"0"	"0"	"514.7"	"431.7"	"466.9"	"514.3"	"434.9"	"446.1"	"589.9"	"702.3"	"646.8"	"912.5"	"1130.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P41091"	"Eukaryotic translation initiation factor 2 subunit 3 OS=Homo sapiens OX=9606 GN=EIF2S3 PE=1 SV=3"	"0.000"	""	"21"	"8"	"15"	"8"	"472"	"51.1"	"8.40"	"3077.35"	"27.99"	"7"	"8"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03144, Pf09173"	"1968"	"ENSG00000130741"	"EIF2S3"	"A0A024RBY4; A8K2Y2; B2R5N2; B5BTZ4; hsa:1968; P41091; Q53HK3"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"ABC-family proteins mediated transport; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK1 (HRI) to heme deficiency; PERK regulates gene expression; Recycling of eIF2:GDP; Response of EIF2AK4 (GCN2) to amino acid deficiency"	"12"	"0"	"755.4"	"604.5"	"715.5"	"647.5"	"623.8"	"718.9"	"1021.2"	"3466.5"	"3522.3"	"4265.1"	"3921.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63208"	"S-phase kinase-associated protein 1 OS=Homo sapiens OX=9606 GN=SKP1 PE=1 SV=2"	"0.000"	""	"42"	"5"	"10"	"5"	"163"	"18.6"	"4.54"	"2377.02"	"27.89"	"4"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf01466, Pf03931"	"6500"	"ENSG00000113558"	"SKP1"	"D3DQ97; D3DQ98; hsa:6500; P34991; P63208; Q8TAY2"	"Cell cycle; TNF-alpha signaling pathway; Breast cancer pathway; Small cell lung cancer; Notch signaling pathway"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; SCF-beta-TrCP mediated degradation of Emi1; Vpu mediated degradation of CD4; Degradation of beta-catenin by the destruction complex; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; NIK-->noncanonical NF-kB signaling; Orc1 removal from chromatin; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Neddylation; SCF(Skp2)-mediated degradation of p27/p21; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Regulation of PLK1 Activity at G2/M Transition; Circadian Clock; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Cyclin D associated events in G1; Regulation of BACH1 activity; MAP3K8 (TPL2)-dependent MAPK1/3 activation; NOTCH1 Intracellular Domain Regulates Transcription; Prolactin receptor signaling; Iron uptake and transport; Nuclear events stimulated by ALK signaling in cancer; Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling"	"38"	"0"	"486.6"	"302.9"	"496.5"	"463.1"	"450.3"	"453.8"	"586.8"	"1231.3"	"1135.6"	"2658.4"	"3511.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14160"	"Protein scribble homolog OS=Homo sapiens OX=9606 GN=SCRIB PE=1 SV=4"	"0.000"	""	"7"	"8"	"16"	"8"	"1630"	"174.8"	"5.07"	"3147.68"	"27.89"	"8"	"8"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"508.8"	"409.8"	"431.4"	"450.9"	"405.2"	"431.6"	"528.6"	"823.4"	"847.7"	"1732.3"	"2682.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96G61"	"Diphosphoinositol polyphosphate phosphohydrolase 3-beta OS=Homo sapiens OX=9606 GN=NUDT11 PE=1 SV=1"	"0.000"	""	"49"	"7"	"13"	"1"	"164"	"18.5"	"5.99"	"2470.49"	"27.84"	"5"	"6"	"other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00293"	"55190"	"ENSG00000196368"	"NUDT11"	"hsa:55190; Q96G61; Q9NVN0"	""	"Synthesis of pyrophosphates in the cytosol"	"1"	"0"	"17.4"	"12.9"	"23.1"	"21.4"	"20.5"	"31.3"	"46.3"	"206.9"	"235.9"	"533.6"	"771.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22061"	"Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens OX=9606 GN=PCMT1 PE=1 SV=4"	"0.000"	""	"26"	"5"	"16"	"5"	"227"	"24.6"	"7.21"	"3735.85"	"27.78"	"5"	"5"	"protein metabolism;other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf01135"	"5110"	"ENSG00000120265"	"PCMT1"	"A8K109; hsa:5110; J3KP72; P22061; Q14661; Q16556; Q5VYC1; Q5VYC2; Q93061; Q96II9; Q99625; Q9BQV7; Q9BQV8; Q9NP03"	"Primary ovarian insufficiency"	"Protein repair"	"2"	"0"	"1060.3"	"907.7"	"1324.3"	"1084.3"	"1110.5"	"1159.7"	"1523.0"	"1840.7"	"1651.4"	"2259.4"	"2797.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BZJ0"	"Crooked neck-like protein 1 OS=Homo sapiens OX=9606 GN=CRNKL1 PE=1 SV=4"	"0.000"	""	"11"	"7"	"13"	"7"	"848"	"100.4"	"8.00"	"2699.14"	"27.75"	"6"	"7"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf02184"	"51340"	"ENSG00000101343"	"CRNKL1"	"A8K9T4; hsa:51340; Q5JY64; Q8WYI5; Q9BZI9; Q9BZJ0; Q9BZJ1; Q9BZJ2; Q9GZW7; Q9H8F8; Q9NQH5; Q9NYD8"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"288.1"	"228.8"	"312.9"	"290.2"	"305.1"	"280.9"	"375.5"	"894.0"	"919.3"	"2885.8"	"4663.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12996"	"Cleavage stimulation factor subunit 3 OS=Homo sapiens OX=9606 GN=CSTF3 PE=1 SV=1"	"0.000"	""	"17"	"8"	"14"	"8"	"717"	"82.9"	"8.12"	"3043.07"	"27.73"	"7"	"7"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf05843"	"1479"	"ENSG00000176102"	"CSTF3"	"A8K471; D3DR04; E9PB40; hsa:1479; Q12996; Q32P22; Q96FQ8; Q96QD6; Q96QK4"	"mRNA processing"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"5"	"0"	"275.1"	"215.9"	"260.2"	"228.2"	"232.6"	"215.9"	"335.7"	"769.8"	"863.2"	"2255.1"	"3354.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N488"	"RING1 and YY1-binding protein OS=Homo sapiens OX=9606 GN=RYBP PE=1 SV=2"	"0.000"	""	"43"	"7"	"10"	"6"	"228"	"24.8"	"9.63"	"1138.46"	"27.64"	"3"	"7"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00641, Pf17219"	"23429"	"ENSG00000163602; ENSG00000281766"	"RYBP"	"hsa:23429; Q8N488; Q9P2W5; Q9UMW4"	""	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Transcriptional Regulation by E2F6"	"2"	"1"	"935.6"	"662.4"	"842.4"	"827.7"	"761.1"	"719.3"	"959.2"	"1712.4"	"1624.6"	"2560.8"	"2876.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P258"	"Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2"	"0.000"	""	"19"	"8"	"16"	"8"	"522"	"56.0"	"8.78"	"3535.64"	"27.54"	"8"	"6"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00415"	"55920"	"ENSG00000179051; ENSG00000281540"	"RCC2"	"hsa:55920; Q8IVL9; Q9BSN6; Q9NPV8; Q9P258"	""	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"6"	"0"	"626.1"	"628.2"	"591.9"	"579.9"	"583.4"	"618.7"	"850.4"	"1430.8"	"1398.9"	"3490.3"	"3924.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WYP5"	"Protein ELYS OS=Homo sapiens OX=9606 GN=AHCTF1 PE=1 SV=3"	"0.000"	""	"4"	"6"	"13"	"6"	"2266"	"252.3"	"6.60"	"2339.79"	"27.45"	"5"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf13934, Pf16687"	"25909"	"ENSG00000153207"	"AHCTF1"	"A6NGM0; A8MSG9; A8MZ86; hsa:25909; Q7Z4E3; Q8IZA4; Q8WYP5; Q96EH9; Q9Y4Q6"	"Gastric cancer network 2"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Postmitotic nuclear pore complex (NPC) reformation"	"8"	"0"	"291.0"	"220.9"	"269.1"	"275.3"	"235.3"	"252.9"	"325.9"	"524.1"	"542.7"	"1120.8"	"1442.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5JWF2"	"Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas OS=Homo sapiens OX=9606 GN=GNAS PE=1 SV=2"	"0.000"	""	"8"	"7"	"13"	"6"	"1037"	"111.0"	"5.03"	"1862.89"	"27.36"	"6"	"7"	"cell adhesion;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00503"	"2778"	"ENSG00000087460"	"GNAS"	"A2A2S3; E1P5G3; O75684; O75685; Q5JW67; Q5JWF1; Q5JWF2; Q9NY42"	"Thyroid stimulating hormone (TSH) signaling pathway; Endothelin pathways; Corticotropin-releasing hormone signaling pathway; Common pathways underlying drug addiction; Myometrial relaxation and contraction pathways; G protein signaling pathways; Thermogenesis; Hippo signaling regulation pathways; Purinergic signaling; GPR143 in melanocytes and retinal pigment epithelium cells; Prostaglandin and leukotriene metabolism in senescence ; Primary ovarian insufficiency; Prostaglandin and leukotriene metabolism in senescence ; Calcium regulation in cardiac cells; Estrogen signaling pathway; Serotonin receptor 4/6/7 and NR3C signaling"	"G alpha (i) signalling events; G alpha (z) signalling events; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Prostacyclin signalling through prostacyclin receptor; Glucagon-type ligand receptors; Vasopressin regulates renal water homeostasis via Aquaporins; PKA activation in glucagon signalling; Hedgehog 'off' state"	"28"	"1"	"324.8"	"292.8"	"332.7"	"278.1"	"271.6"	"263.4"	"343.5"	"739.9"	"786.9"	"2448.4"	"3789.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P60660"	"Myosin light polypeptide 6 OS=Homo sapiens OX=9606 GN=MYL6 PE=1 SV=2"	"0.000"	""	"54"	"7"	"15"	"7"	"151"	"16.9"	"4.65"	"3017.28"	"26.94"	"7"	"6"	"other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	""	"4637"	"ENSG00000092841"	"MYL6"	"hsa:4637; P16475; P24572; P24573; P60660; Q12790; Q561V9; Q6IAZ0; Q6IPY5"	"Ciliary landscape"	"RHO GTPases activate CIT; EPHA-mediated growth cone collapse; Sema4D induced cell migration and growth-cone collapse; Smooth Muscle Contraction; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; RHO GTPases activate PAKs"	"8"	"0"	"296.7"	"229.5"	"303.5"	"261.1"	"253.3"	"228.1"	"319.5"	"787.3"	"715.8"	"2396.4"	"3758.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13283"	"Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1"	"0.000"	""	"25"	"8"	"14"	"8"	"466"	"52.1"	"5.52"	"2441.81"	"26.88"	"7"	"7"	"cell organization and biogenesis;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00076, Pf02136"	"10146"	"ENSG00000145907"	"G3BP1"	"hsa:10146; Q13283; Q5HYE9"	""	"SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"1"	"0"	"297.7"	"264.9"	"345.9"	"298.3"	"308.2"	"336.9"	"444.3"	"755.3"	"723.0"	"1468.0"	"1907.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P99999"	"Cytochrome c OS=Homo sapiens OX=9606 GN=CYCS PE=1 SV=2"	"0.000"	""	"55"	"6"	"16"	"6"	"105"	"11.7"	"9.57"	"2855.96"	"26.86"	"5"	"6"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"other membranes;cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf00034"	"54205"	"ENSG00000172115"	"CYCS"	"A4D166; B2R4I1; hsa:54205; P00001; P99999; Q6NUR2; Q6NX69; Q96BV4"	"miRNA regulation of DNA damage response; Apoptosis modulation and signaling; Alzheimer's disease and miRNA effects; AGE/RAGE pathway; Parkinson's disease pathway; Nanomaterial induced apoptosis; Apoptosis; Fas ligand pathway and stress induction of heat shock proteins; Apoptosis modulation by HSP70; VEGFA-VEGFR2 signaling; Oxidative damage response; NO/cGMP/PKG mediated neuroprotection; Chromosomal and microsatellite instability in colorectal cancer ; Non-small cell lung cancer; Acute viral myocarditis; Nonalcoholic fatty liver disease; Measles virus infection; Small cell lung cancer; Hepatitis B infection; IL-18 signaling pathway; Pleural mesothelioma; Complement system in neuronal development and plasticity; Alzheimer's disease; DNA damage response"	"Respiratory electron transport; Detoxification of Reactive Oxygen Species; Transcriptional activation of mitochondrial biogenesis; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1; Activation of caspases through apoptosome-mediated cleavage; SMAC (DIABLO) binds to IAPs ; SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes ; Regulation of the apoptosome activity; Release of apoptotic factors from the mitochondria; Pyroptosis"	"36"	"0"	"1611.4"	"2082.0"	"1693.1"	"1771.4"	"2226.5"	"2148.5"	"3100.6"	"1863.8"	"1589.9"	"2298.4"	"2953.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14151"	"Scaffold attachment factor B2 OS=Homo sapiens OX=9606 GN=SAFB2 PE=1 SV=1"	"0.000"	""	"9"	"7"	"15"	"3"	"953"	"107.4"	"6.16"	"2226.53"	"26.84"	"5"	"6"	"developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf02037"	"9667"	"ENSG00000130254"	"SAFB2"	"B4DKG3; hsa:9667; Q14151; Q8TB13"	""	""	"0"	"0"	"192.0"	"133.8"	"212.8"	"166.4"	"172.0"	"185.3"	"239.7"	"396.8"	"364.4"	"986.1"	"1448.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y230"	"RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3"	"0.000"	""	"21"	"9"	"19"	"9"	"463"	"51.1"	"5.64"	"3199.79"	"26.81"	"9"	"9"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06068, Pf17856"	"10856"	"ENSG00000183207"	"RUVBL2"	"B3KQ59; E7ETE5; hsa:10856; Q6FIB9; Q6PK27; Q9Y230; Q9Y361"	""	"HATs acetylate histones; Telomere Extension By Telomerase"	"2"	"0"	"477.8"	"393.7"	"487.1"	"403.0"	"385.4"	"424.8"	"540.8"	"986.0"	"958.6"	"2304.7"	"3470.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86VM9"	"Zinc finger CCCH domain-containing protein 18 OS=Homo sapiens OX=9606 GN=ZC3H18 PE=1 SV=2"	"0.000"	""	"12"	"12"	"19"	"12"	"953"	"106.3"	"8.32"	"3241.21"	"26.80"	"11"	"8"	"other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf18044"	"124245"	"ENSG00000158545"	"ZC3H18"	"hsa:124245; Q86VM9; Q96DG4; Q96MP7"	""	""	"0"	"0"	"2079.8"	"1721.6"	"1861.3"	"1878.2"	"1740.0"	"1774.1"	"2247.8"	"2447.6"	"2309.6"	"3384.8"	"4808.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P2I0"	"Cleavage and polyadenylation specificity factor subunit 2 OS=Homo sapiens OX=9606 GN=CPSF2 PE=1 SV=2"	"0.000"	""	"15"	"8"	"13"	"8"	"782"	"88.4"	"5.11"	"1514.84"	"26.74"	"5"	"8"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf07521, Pf10996, Pf13299, Pf16661"	"53981"	"ENSG00000165934"	"CPSF2"	"B3KME1; hsa:53981; Q6NSJ1; Q9H3W7; Q9P2I0"	"mRNA processing"	"Transport of Mature mRNA Derived from an Intronless Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"6"	"0"	"383.2"	"314.2"	"379.6"	"313.2"	"351.8"	"324.0"	"443.1"	"730.1"	"720.8"	"1606.1"	"2330.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14839"	"Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2"	"0.000"	""	"5"	"8"	"15"	"8"	"1912"	"217.9"	"5.86"	"2458.37"	"26.73"	"7"	"8"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf00385, Pf00628, Pf06461, Pf06465, Pf08073, Pf08074"	"1108"	"ENSG00000111642"	"CHD4"	"hsa:1108; Q14839; Q8IXZ5"	"Rett syndrome causing genes; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"Potential therapeutics for SARS; HDACs deacetylate histones; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of PTEN gene transcription; RNA Polymerase I Transcription Initiation; Regulation of TP53 Activity through Acetylation; NGF-stimulated transcription"	"9"	"0"	"638.7"	"482.6"	"663.5"	"590.1"	"558.9"	"588.0"	"792.5"	"1317.5"	"1299.4"	"3141.8"	"3637.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05387"	"60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1"	"0.000"	""	"75"	"5"	"12"	"4"	"115"	"11.7"	"4.54"	"2701.27"	"26.73"	"4"	"4"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf00428"	"6181"	"ENSG00000177600"	"RPLP2"	"hsa:6181; P05387; Q6FG96"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins; Opioid receptor pathways"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"16"	"1"	"226.1"	"182.3"	"301.2"	"242.6"	"226.5"	"254.5"	"337.6"	"943.4"	"895.5"	"1768.1"	"2766.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62263"	"40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3"	"0.000"	""	"41"	"6"	"10"	"6"	"151"	"16.3"	"10.05"	"1783.63"	"26.73"	"4"	"6"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00411"	"6208"	"ENSG00000164587"	"RPS14"	"B2R5G5; D3DQG5; hsa:6208; P06366; P62263; Q5BJI0"	"Cytoplasmic ribosomal proteins"	"Major pathway of rRNA processing in the nucleolus and cytosol; Regulation of expression of SLITs and ROBOs; rRNA modification in the nucleus and cytosol; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"20"	"0"	"290.7"	"214.1"	"251.5"	"236.9"	"243.5"	"274.7"	"358.5"	"442.7"	"507.0"	"856.7"	"1249.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BY77"	"Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2"	"0.000"	""	"25"	"7"	"12"	"7"	"421"	"46.1"	"9.99"	"2296.22"	"26.71"	"5"	"6"	"other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"84271"	"ENSG00000100227"	"POLDIP3"	"A8K6F8; A8K6V9; hsa:84271; Q009A7; Q5H972; Q6PGN6; Q7Z6Z0; Q9BY77; Q9NSP5; Q9NSP6"	""	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript"	"3"	"0"	"549.6"	"453.0"	"563.4"	"549.5"	"490.7"	"517.8"	"639.7"	"858.9"	"826.7"	"1362.3"	"2136.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NTI5"	"Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens OX=9606 GN=PDS5B PE=1 SV=1"	"0.000"	""	"7"	"7"	"12"	"5"	"1447"	"164.6"	"8.47"	"1709.40"	"26.60"	"5"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf20168"	"23047"	"ENSG00000083642"	"PDS5B"	"hsa:23047; Q5R3S3; Q5W0K8; Q6NSC3; Q8IXT6; Q9H5N8; Q9NTI5; Q9Y2I5; Q9Y451"	"Cohesin complex - Cornelia de Lange syndrome; 10q22q23 copy number variation"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"6"	"0"	"214.0"	"197.9"	"260.7"	"269.2"	"240.4"	"246.3"	"307.6"	"517.5"	"541.8"	"970.3"	"1247.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13428"	"Treacle protein OS=Homo sapiens OX=9606 GN=TCOF1 PE=1 SV=3"	"0.000"	""	"8"	"11"	"20"	"11"	"1488"	"152.0"	"9.04"	"4710.14"	"26.53"	"11"	"8"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf03546"	"6949"	"ENSG00000070814"	"TCOF1"	"A0JLU0; B4E111; hsa:6949; Q13428; Q6SC72; Q7Z5W9; Q96A52; Q99408; Q99860"	""	""	"0"	"0"	"1520.8"	"1291.9"	"1374.5"	"1347.1"	"1270.0"	"1306.8"	"1658.6"	"2288.9"	"2190.7"	"3409.0"	"4176.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q04837"	"Single-stranded DNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SSBP1 PE=1 SV=1"	"0.000"	""	"50"	"7"	"12"	"7"	"148"	"17.2"	"9.60"	"1894.29"	"26.50"	"5"	"7"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00436"	"6742"	"ENSG00000106028; ENSG00000262771"	"SSBP1"	"hsa:6742; Q04837"	""	"Transcriptional activation of mitochondrial biogenesis"	"1"	"0"	"393.6"	"325.6"	"375.9"	"379.0"	"370.1"	"383.5"	"523.3"	"818.8"	"743.6"	"2002.9"	"2647.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NFP7"	"Diphosphoinositol polyphosphate phosphohydrolase 3-alpha OS=Homo sapiens OX=9606 GN=NUDT10 PE=1 SV=1"	"0.000"	""	"49"	"7"	"13"	"1"	"164"	"18.5"	"5.68"	"2248.11"	"26.49"	"5"	"6"	"other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00293"	"170685"	"ENSG00000122824"	"NUDT10"	"A8K7D7; D3DX69; hsa:170685; Q86VK1; Q86VR0; Q8NFP7"	""	"Synthesis of pyrophosphates in the cytosol"	"1"	"6"	"193.5"	"133.1"	"214.7"	"197.1"	"230.5"	"436.3"	"793.7"	"2361.1"	"2353.0"	"5698.5"	"7399.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12769"	"Nuclear pore complex protein Nup160 OS=Homo sapiens OX=9606 GN=NUP160 PE=1 SV=3"	"0.000"	""	"4"	"6"	"14"	"6"	"1436"	"162.0"	"5.50"	"2990.58"	"26.39"	"6"	"6"	"other metabolic processes;transport;developmental processes"	"cytosol;nucleus"	"other molecular function"	"Pf11715"	"23279"	"ENSG00000030066"	"NUP160"	"B4DYE8; B4E2J9; hsa:23279; Q08AD3; Q12769; Q7Z5X6; Q96GB3; Q9H660"	""	"Rev-mediated nuclear export of HIV RNA; Nuclear import of Rev protein; Postmitotic nuclear pore complex (NPC) reformation; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; HCMV Late Events; HCMV Early Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"35"	"0"	"795.7"	"569.0"	"797.2"	"753.3"	"636.2"	"702.2"	"965.5"	"1282.0"	"1278.1"	"2524.7"	"3112.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NUP9"	"Protein lin-7 homolog C OS=Homo sapiens OX=9606 GN=LIN7C PE=1 SV=1"	"0.000"	""	"22"	"7"	"17"	"4"	"197"	"21.8"	"8.43"	"3486.37"	"26.34"	"7"	"6"	"cell-cell signaling;transport;other biological processes"	"plasma membrane;other membranes;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00595, Pf02828"	"55327"	"ENSG00000148943"	"LIN7C"	"hsa:55327; Q9NUP9"	""	"Neurexins and neuroligins; Assembly and cell surface presentation of NMDA receptors; Dopamine Neurotransmitter Release Cycle"	"3"	"3"	"969.9"	"722.6"	"929.0"	"792.4"	"725.1"	"750.4"	"1008.9"	"2364.6"	"2415.8"	"5591.4"	"6577.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05141"	"ADP/ATP translocase 2 OS=Homo sapiens OX=9606 GN=SLC25A5 PE=1 SV=7"	"0.000"	""	"29"	"8"	"17"	"3"	"298"	"32.8"	"9.69"	"3446.22"	"26.28"	"7"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytoskeleton;mitochondrion"	"transporter activity;other molecular function"	"Pf00153"	"292"	"ENSG00000005022"	"SLC25A5"	"B2RCV1; hsa:292; O43350; P05141"	"Electron transport chain: OXPHOS system in mitochondria; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane; Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization"	"5"	"5"	"797.3"	"641.9"	"803.2"	"750.9"	"675.0"	"730.0"	"994.5"	"1699.5"	"1689.8"	"4175.0"	"5817.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16629"	"Serine/arginine-rich splicing factor 7 OS=Homo sapiens OX=9606 GN=SRSF7 PE=1 SV=1"	"0.000"	""	"26"	"6"	"11"	"6"	"238"	"27.4"	"11.82"	"928.86"	"26.20"	"3"	"6"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6432"	"ENSG00000115875"	"SRSF7"	"B4DLU6; G5E9M3; hsa:6432; Q16629; Q564D3"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; mRNA Splicing - Minor Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript"	"7"	"0"	"838.4"	"718.6"	"773.7"	"730.1"	"689.8"	"696.1"	"1012.0"	"1373.5"	"1134.9"	"2107.8"	"3296.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P53621"	"Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2"	"0.000"	""	"9"	"9"	"16"	"9"	"1224"	"138.3"	"7.66"	"2888.55"	"26.16"	"8"	"8"	"transport;signal transduction"	"non-structural extracellular;other membranes;cytosol;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00400, Pf04053, Pf06957, Pf12894"	"1314"	"ENSG00000122218"	"COPA"	"hsa:1314; P53621; Q5T201; Q8IXZ9"	""	"COPI-mediated anterograde transport; COPI-dependent Golgi-to-ER retrograde traffic"	"2"	"0"	"490.7"	"391.8"	"497.6"	"472.2"	"455.9"	"445.8"	"559.0"	"887.3"	"891.9"	"1977.8"	"2889.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61160"	"Actin-related protein 2 OS=Homo sapiens OX=9606 GN=ACTR2 PE=1 SV=1"	"0.000"	""	"25"	"9"	"16"	"9"	"394"	"44.7"	"6.74"	"3003.01"	"26.13"	"9"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00022"	"10097"	"ENSG00000138071"	"ACTR2"	"B2RCP5; D6W5F4; E9PF41; hsa:10097; O15142; P61160; Q96C82"	"Physico-chemical features and toxicity-associated pathways; Embryonic stem cell pluripotency pathways"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Neutrophil degranulation; Clathrin-mediated endocytosis; EPHB-mediated forward signaling"	"8"	"0"	"512.9"	"340.6"	"480.7"	"437.3"	"453.1"	"436.8"	"581.8"	"1933.6"	"1823.3"	"4030.5"	"4844.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30405"	"Peptidyl-prolyl cis-trans isomerase F, mitochondrial OS=Homo sapiens OX=9606 GN=PPIF PE=1 SV=1"	"0.000"	""	"40"	"7"	"17"	"5"	"207"	"22.0"	"9.38"	"2783.19"	"26.13"	"6"	"6"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"other membranes;mitochondrion;other cell component"	"other molecular function"	"Pf00160"	"10105"	"ENSG00000108179"	"PPIF"	"hsa:10105; P30405; Q2YDB7; Q5W131"	"Alzheimer's disease and miRNA effects; Alzheimer's disease"	""	"2"	"1"	"1861.8"	"1726.5"	"2083.9"	"1899.1"	"1807.5"	"1729.5"	"2275.2"	"3410.6"	"2998.6"	"6445.4"	"7341.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62995"	"Transformer-2 protein homolog beta OS=Homo sapiens OX=9606 GN=TRA2B PE=1 SV=1"	"0.000"	""	"26"	"7"	"14"	"7"	"288"	"33.6"	"11.25"	"1903.31"	"26.11"	"5"	"7"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6434"	"ENSG00000136527"	"TRA2B"	"B4DVK2; D3DNU3; hsa:6434; O15449; P62995; Q15815; Q64283"	"mRNA processing"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle"	"5"	"0"	"1358.6"	"1123.4"	"1199.9"	"1101.1"	"1110.1"	"1075.1"	"1412.1"	"1481.3"	"1337.2"	"1938.0"	"2974.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14936"	"Peripheral plasma membrane protein CASK OS=Homo sapiens OX=9606 GN=CASK PE=1 SV=3"	"0.000"	""	"9"	"7"	"13"	"7"	"926"	"105.1"	"6.43"	"2398.49"	"26.10"	"6"	"7"	"cell adhesion;protein metabolism;other metabolic processes;transport;other biological processes"	"extracellular matrix;plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;kinase activity;other molecular function"	"Pf00018, Pf00069, Pf00595, Pf00625, Pf02828"	"8573"	"ENSG00000147044"	"CASK"	"A6NES1; B7ZKY0; hsa:8573; O14936; O43215; Q17RI4; Q59HA0; Q5VT16; Q5VT17; Q5VT18; Q5VT19; Q66T42; Q9BYH6; Q9NYB2; Q9NYB3"	"Parkin-ubiquitin proteasomal system pathway; Splicing factor NOVA regulated synaptic proteins"	"Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Assembly and cell surface presentation of NMDA receptors; Nephrin family interactions; Neurexins and neuroligins; Dopamine Neurotransmitter Release Cycle; Syndecan interactions"	"9"	"0"	"368.0"	"280.4"	"387.1"	"351.2"	"324.8"	"309.0"	"411.4"	"1138.8"	"1196.5"	"2854.0"	"3389.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P12236"	"ADP/ATP translocase 3 OS=Homo sapiens OX=9606 GN=SLC25A6 PE=1 SV=4"	"0.000"	""	"23"	"7"	"16"	"1"	"298"	"32.8"	"9.74"	"2816.13"	"26.09"	"6"	"7"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity"	"Pf00153"	"293"	"ENSG00000169100"	"SLC25A6"	"hsa:293; P12236; Q96C49"	"Electron transport chain: OXPHOS system in mitochondria; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Mitochondrial protein import; Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane; Influenza Virus Induced Apoptosis; Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization"	"7"	"1"	"112.1"	"84.9"	"145.9"	"104.2"	"118.5"	"123.5"	"158.7"	"358.7"	"392.3"	"873.5"	"1256.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50395"	"Rab GDP dissociation inhibitor beta OS=Homo sapiens OX=9606 GN=GDI2 PE=1 SV=2"	"0.000"	""	"14"	"5"	"9"	"5"	"445"	"50.6"	"6.47"	"1272.41"	"26.07"	"2"	"5"	"transport;signal transduction;other biological processes"	"non-structural extracellular;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00996"	"2665"	"ENSG00000057608"	"GDI2"	"hsa:2665; O43928; P50395; Q5SX88; Q9UQM6"	""	"Neutrophil degranulation; RAB GEFs exchange GTP for GDP on RABs"	"2"	"0"	"91.2"	"67.7"	"118.2"	"110.0"	"93.9"	"91.6"	"121.7"	"256.0"	"262.6"	"1180.4"	"4209.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q00610"	"Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5"	"0.000"	""	"5"	"7"	"14"	"7"	"1675"	"191.5"	"5.69"	"3049.95"	"26.04"	"7"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00637, Pf01394, Pf09268, Pf13838"	"1213"	"ENSG00000141367"	"CLTC"	"D3DU00; hsa:1213; Q00610; Q6N0A0; Q86TF2"	"Synaptic vesicle pathway; VEGFA-VEGFR2 signaling; Ebola virus infection in host; Fragile X syndrome; 7q11.23 copy number variation syndrome; Complement and coagulation cascades"	"ALK mutants bind TKIs; Nuclear events stimulated by ALK signaling in cancer; Recycling pathway of L1; MHC class II antigen presentation; RHOV GTPase cycle; Lysosome Vesicle Biogenesis; RHOU GTPase cycle; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; LDL clearance; Retrograde neurotrophin signalling; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; VLDLR internalisation and degradation; Entry of Influenza Virion into Host Cell via Endocytosis; Formation of annular gap junctions"	"25"	"0"	"787.3"	"693.9"	"652.4"	"594.6"	"633.5"	"599.3"	"882.3"	"1429.8"	"1334.1"	"2327.5"	"3223.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BQ61"	"Telomerase RNA component interacting RNase OS=Homo sapiens OX=9606 GN=TRIR PE=1 SV=1"	"0.000"	""	"32"	"7"	"8"	"7"	"176"	"18.4"	"9.44"	"463.74"	"25.98"	"2"	"6"	"RNA metabolism OR transcription;other metabolic processes"	""	"nucleic acid binding activity;other molecular function"	""	"79002"	"ENSG00000123144"	"TRIR"	"hsa:79002; Q9BQ61"	""	""	"0"	"0"	"762.2"	"653.5"	"723.2"	"695.1"	"708.3"	"629.4"	"901.2"	"1746.2"	"1681.6"	"3266.7"	"3407.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P31689"	"DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2"	"0.000"	""	"21"	"7"	"12"	"6"	"397"	"44.8"	"7.08"	"1959.77"	"25.96"	"6"	"5"	"protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00226, Pf00684, Pf01556"	"3301"	"ENSG00000086061"	"DNAJA1"	"hsa:3301; P31689; Q5T7Q0; Q86TL9"	"VEGFA-VEGFR2 signaling; Exercise-induced circadian regulation"	"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand"	"3"	"1"	"671.0"	"493.4"	"696.1"	"643.2"	"589.5"	"614.1"	"789.2"	"1703.8"	"1632.1"	"4042.7"	"5113.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N1G4"	"Leucine-rich repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=LRRC47 PE=1 SV=1"	"0.000"	""	"14"	"7"	"13"	"7"	"583"	"63.4"	"8.28"	"2365.41"	"25.93"	"6"	"7"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	""	"other molecular function"	"Pf00560, Pf03483, Pf12799"	"57470"	"ENSG00000130764"	"LRRC47"	"hsa:57470; Q8N1G4; Q9ULN5"	""	""	"0"	"0"	"397.0"	"292.0"	"397.6"	"350.0"	"331.9"	"368.1"	"475.8"	"1383.4"	"1318.3"	"2123.2"	"2135.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P36873"	"Serine/threonine-protein phosphatase PP1-gamma catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CC PE=1 SV=1"	"0.000"	""	"23"	"6"	"12"	"2"	"323"	"37.0"	"6.54"	"2645.48"	"25.78"	"6"	"6"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00149, Pf16891"	"5501"	"ENSG00000186298"	"PPP1CC"	"hsa:5501; P36873"	"Common pathways underlying drug addiction; Focal adhesion; Hippo-Merlin signaling dysregulation; Neuroinflammation and glutamatergic signaling"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Downregulation of TGF-beta receptor signaling; Triglyceride catabolism; Circadian Clock; RAF activation; SHOC2 M1731 mutant abolishes MRAS complex function; Gain-of-function MRAS complexes activate RAF signaling"	"16"	"0"	"472.7"	"366.7"	"450.3"	"448.5"	"445.7"	"427.8"	"526.9"	"826.2"	"794.2"	"1656.1"	"1873.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P0DP25"	"Calmodulin-3 OS=Homo sapiens OX=9606 GN=CALM3 PE=1 SV=1"	"0.000"	""	"32"	"7"	"13"	"7"	"149"	"16.8"	"4.22"	"2713.23"	"25.72"	"6"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;mitochondrion;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf13499"	"801; 805; 808"	"ENSG00000160014"	"CALM3"	"hsa:801; hsa:805; hsa:808; P02593; P0DP25; P62158; P70667; P99014; Q13942; Q53S29; Q61379; Q61380; Q96HK3"	"Physiological and pathological hypertrophy of the heart; MicroRNAs in cardiomyocyte hypertrophy; Alzheimer's disease and miRNA effects; T cell receptor and co-stimulatory signaling; Cardiac hypertrophic response; Myometrial relaxation and contraction pathways; G protein signaling pathways; Ras signaling; Melanoma; Endochondral ossification; Endochondral ossification with skeletal dysplasias; CAMKK2 pathway; Glycogen synthesis and degradation; Neuroinflammation and glutamatergic signaling; Alzheimer's disease; G13 signaling pathway; Calcium regulation in cardiac cells"	""	"17"	"0"	"1179.3"	"953.4"	"1083.9"	"967.3"	"933.5"	"1031.1"	"1344.1"	"2565.4"	"2354.6"	"4095.9"	"5597.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11387"	"DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2"	"0.000"	""	"12"	"8"	"16"	"8"	"765"	"90.7"	"9.31"	"2577.11"	"25.68"	"7"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf01028, Pf02919, Pf14370"	"7150"	"ENSG00000198900"	"TOP1"	"A8KA78; E1P5W3; hsa:7150; O43256; P11387; Q12855; Q12856; Q15610; Q5TFY3; Q9UJN0"	"Ebola virus infection in host; 15q25 copy number variation"	"SUMOylation of DNA replication proteins"	"3"	"0"	"428.2"	"337.2"	"396.6"	"398.3"	"395.4"	"409.5"	"490.1"	"1252.8"	"1189.8"	"2283.9"	"2544.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q07021"	"Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1"	"0.000"	""	"27"	"5"	"12"	"5"	"282"	"31.3"	"4.84"	"2582.91"	"25.67"	"4"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;translation activity;nucleic acid binding activity;other molecular function"	"Pf02330"	"708"	"ENSG00000108561"	"C1QBP"	"hsa:708; Q07021; Q2HXR8; Q9NNY8"	"Complement system; Mesodermal commitment pathway; Ebola virus infection in host"	"RHOC GTPase cycle; RHOA GTPase cycle; Intrinsic Pathway of Fibrin Clot Formation; Apoptotic factor-mediated response; Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function"	"8"	"0"	"576.1"	"381.7"	"503.1"	"491.9"	"472.7"	"488.2"	"620.2"	"766.1"	"735.9"	"1345.3"	"1811.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49790"	"Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2"	"0.000"	""	"6"	"7"	"14"	"7"	"1475"	"153.8"	"8.73"	"2929.05"	"25.61"	"7"	"7"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00641, Pf08604, Pf10599"	"9972"	"ENSG00000124789"	"NUP153"	"B4DIK2; E7EPX5; F6QR24; hsa:9972; P49790; Q4LE47; Q5T9I7; Q7Z743"	""	"Nuclear import of Rev protein; HCMV Late Events; HCMV Early Events; Transcriptional regulation by small RNAs; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"28"	"0"	"655.3"	"421.7"	"641.0"	"585.3"	"500.8"	"501.7"	"698.1"	"1144.7"	"1029.8"	"1911.7"	"2309.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95639"	"Cleavage and polyadenylation specificity factor subunit 4 OS=Homo sapiens OX=9606 GN=CPSF4 PE=1 SV=1"	"0.000"	""	"35"	"6"	"9"	"6"	"269"	"30.2"	"8.31"	"1001.78"	"25.60"	"3"	"5"	""	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00098, Pf00642, Pf15663"	"10898"	"ENSG00000160917"	"CPSF4"	"D6W5S8; hsa:10898; O95639; Q6FGE6; Q86TF8; Q9BTW6"	"mRNA processing"	"Transport of Mature mRNA Derived from an Intronless Transcript; tRNA processing in the nucleus; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs; Inhibition of Host mRNA Processing and RNA Silencing"	"8"	"0"	"328.9"	"272.4"	"300.5"	"293.5"	"287.1"	"233.1"	"403.6"	"623.0"	"571.1"	"1558.7"	"2691.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13523"	"Serine/threonine-protein kinase PRP4 homolog OS=Homo sapiens OX=9606 GN=PRPF4B PE=1 SV=3"	"0.000"	""	"9"	"9"	"18"	"9"	"1007"	"116.9"	"10.26"	"3573.97"	"25.60"	"8"	"5"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"8899"	"ENSG00000112739"	"PRPF4B"	"A8K5C9; hsa:8899; Q13523; Q5D0F6; Q5TAY8; Q8IVC3; Q8TDP2; Q96QT7; Q9UEE6"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"1152.5"	"942.0"	"1209.1"	"1075.8"	"1095.5"	"1075.3"	"1414.7"	"2231.5"	"2092.1"	"4977.0"	"7184.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5T2T1"	"MAGUK p55 subfamily member 7 OS=Homo sapiens OX=9606 GN=MPP7 PE=1 SV=1"	"0.000"	""	"21"	"8"	"13"	"8"	"576"	"65.5"	"7.14"	"2960.31"	"25.49"	"6"	"6"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00018, Pf00595, Pf00625, Pf02828"	"143098"	"ENSG00000150054"	"MPP7"	"B2RCC9; B4DWL9; B5MDZ3; D3DRW3; hsa:143098; Q5T2T0; Q5T2T1; Q8IY28"	""	"RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOQ GTPase cycle; RHOG GTPase cycle; RHOJ GTPase cycle"	"6"	"0"	"210.7"	"149.8"	"223.0"	"214.8"	"208.8"	"215.6"	"290.6"	"597.8"	"608.7"	"1166.4"	"1413.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q00341"	"Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2"	"0.000"	""	"8"	"8"	"13"	"8"	"1268"	"141.4"	"6.87"	"1965.93"	"25.40"	"5"	"8"	"other metabolic processes;transport"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013"	"3069"	"ENSG00000115677"	"HDLBP"	"B4DTQ2; E7EM71; hsa:3069; Q00341; Q53QU2; Q9UCY3"	"2q37 copy number variation syndrome"	"HDL clearance"	"2"	"0"	"420.8"	"317.8"	"449.0"	"411.6"	"433.0"	"453.7"	"527.0"	"949.4"	"949.4"	"2365.4"	"2988.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VTL8"	"Pre-mRNA-splicing factor 38B OS=Homo sapiens OX=9606 GN=PRPF38B PE=1 SV=1"	"0.000"	""	"15"	"7"	"14"	"7"	"546"	"64.4"	"10.54"	"2517.96"	"25.35"	"7"	"7"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf03371"	"55119"	"ENSG00000134186"	"PRPF38B"	"hsa:55119; Q05DD6; Q32Q58; Q5VTL8; Q5VTL9; Q6PK39; Q7Z6E2; Q86WF3; Q8IWG9; Q9NW40"	""	""	"0"	"0"	"615.0"	"445.2"	"560.0"	"482.2"	"489.7"	"517.1"	"638.5"	"1003.8"	"890.4"	"1801.4"	"2485.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5SRE5"	"Nucleoporin NUP188 homolog OS=Homo sapiens OX=9606 GN=NUP188 PE=1 SV=1"	"0.000"	""	"6"	"8"	"15"	"8"	"1749"	"195.9"	"6.73"	"3238.87"	"25.18"	"8"	"7"	"transport"	"cytosol;nucleus"	"other molecular function"	"Pf10487"	"23511"	"ENSG00000095319"	"NUP188"	"hsa:23511; Q14675; Q2TA87; Q5SRE5; Q7Z3K8; Q8IWF1"	""	"SARS-CoV-2 activates/modulates innate and adaptive immune responses; Regulation of HSF1-mediated heat shock response; HCMV Late Events; HCMV Early Events; Transcriptional regulation by small RNAs; SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Transport of Mature mRNA Derived from an Intronless Transcript; tRNA processing in the nucleus; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; SUMOylation of SUMOylation proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); Postmitotic nuclear pore complex (NPC) reformation"	"29"	"0"	"239.8"	"177.3"	"202.1"	"212.1"	"193.5"	"190.6"	"233.3"	"447.6"	"453.4"	"986.0"	"1239.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NQG5"	"Regulation of nuclear pre-mRNA domain-containing protein 1B OS=Homo sapiens OX=9606 GN=RPRD1B PE=1 SV=1"	"0.000"	""	"24"	"8"	"16"	"6"	"326"	"36.9"	"5.97"	"3696.89"	"25.14"	"8"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf04818, Pf16566"	"58490"	"ENSG00000101413"	"RPRD1B"	"hsa:58490; Q1WDE7; Q6PKF4; Q9NQG5"	"Modulators of TCR signaling and T cell activation"	"RNA polymerase II transcribes snRNA genes"	"2"	"0"	"209.3"	"139.2"	"207.7"	"199.3"	"196.7"	"204.8"	"253.2"	"518.4"	"505.6"	"1450.2"	"2177.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13769"	"THO complex subunit 5 homolog OS=Homo sapiens OX=9606 GN=THOC5 PE=1 SV=2"	"0.000"	""	"12"	"6"	"13"	"6"	"683"	"78.5"	"6.87"	"2438.96"	"25.07"	"5"	"6"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf09766"	"8563"	"ENSG00000100296"	"THOC5"	"hsa:8563; O60839; Q13769; Q9UPZ5"	""	"Signaling by CSF1 (M-CSF) in myeloid cells; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"4"	"0"	"369.3"	"254.1"	"439.3"	"381.3"	"362.1"	"359.8"	"484.4"	"711.8"	"680.2"	"1292.8"	"1830.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14927"	"Cytochrome b-c1 complex subunit 7 OS=Homo sapiens OX=9606 GN=UQCRB PE=1 SV=2"	"0.000"	""	"55"	"6"	"11"	"6"	"111"	"13.5"	"8.78"	"2211.54"	"25.00"	"5"	"6"	"other metabolic processes;transport"	"other membranes;mitochondrion"	""	"Pf02271"	"7381"	"ENSG00000156467"	"UQCRB"	"E5RJU0; hsa:7381; P14927; Q6FGD1"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex III assembly"	"Respiratory electron transport"	"4"	"0"	"542.0"	"452.5"	"598.6"	"531.4"	"546.1"	"559.5"	"705.0"	"1056.0"	"1064.1"	"1971.5"	"2756.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NRZ9"	"Lymphoid-specific helicase OS=Homo sapiens OX=9606 GN=HELLS PE=1 SV=1"	"0.000"	""	"12"	"7"	"11"	"7"	"838"	"97.0"	"7.93"	"2138.00"	"24.97"	"5"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00176, Pf00271"	"3070"	"ENSG00000119969"	"HELLS"	"B2RB41; hsa:3070; Q3LID1; Q6I7N7; Q76H76; Q76H77; Q76H78; Q76H79; Q76H80; Q76H81; Q7Z397; Q7Z5X2; Q8N6P4; Q9H4P5; Q9NRZ9"	"Apoptosis; Apoptosis-related network due to altered Notch3 in ovarian cancer"	""	"2"	"0"	"578.2"	"492.5"	"564.8"	"549.4"	"516.5"	"530.6"	"680.0"	"1102.4"	"1034.7"	"1782.1"	"2171.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P48444"	"Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1"	"0.000"	""	"17"	"7"	"14"	"7"	"511"	"57.2"	"6.21"	"2655.24"	"24.97"	"7"	"7"	"transport;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi"	""	"Pf00928, Pf01217"	"372"	"ENSG00000095139"	"ARCN1"	"B4E1X2; E9PEU4; hsa:372; P48444; Q52M80"	"miR-517 relationship with ARCN1 and USP1"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport"	"3"	"0"	"312.4"	"268.0"	"298.4"	"270.3"	"285.0"	"314.7"	"342.8"	"650.1"	"674.6"	"2295.2"	"3210.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P06744"	"Glucose-6-phosphate isomerase OS=Homo sapiens OX=9606 GN=GPI PE=1 SV=4"	"0.000"	""	"17"	"7"	"13"	"7"	"558"	"63.1"	"8.32"	"2011.97"	"24.95"	"5"	"6"	"other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00342"	"2821"	"ENSG00000105220"	"GPI"	"B4DG39; hsa:2821; P06744; Q9BRD3; Q9BSK5; Q9UHE6"	"Cori cycle; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Aerobic glycolysis; N-glycan biosynthesis; Disorders of fructose metabolism; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders; UDP-derived sugars synthesis in fibroblasts"	"Neutrophil degranulation; TP53 Regulates Metabolic Genes; Glycolysis; Gluconeogenesis"	"13"	"0"	"351.4"	"298.7"	"426.0"	"405.3"	"378.4"	"410.4"	"488.5"	"1250.4"	"1436.1"	"4497.4"	"7269.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q05048"	"Cleavage stimulation factor subunit 1 OS=Homo sapiens OX=9606 GN=CSTF1 PE=1 SV=1"	"0.000"	""	"25"	"8"	"11"	"8"	"431"	"48.3"	"6.58"	"1865.47"	"24.82"	"5"	"6"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf00400, Pf16699"	"1477"	"ENSG00000101138"	"CSTF1"	"hsa:1477; Q05048; Q5QPD8"	"mRNA processing"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"5"	"0"	"409.0"	"333.5"	"378.1"	"366.4"	"338.6"	"335.7"	"476.8"	"966.7"	"873.2"	"2689.5"	"4511.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13642"	"Four and a half LIM domains protein 1 OS=Homo sapiens OX=9606 GN=FHL1 PE=1 SV=4"	"0.000"	""	"21"	"6"	"11"	"6"	"323"	"36.2"	"8.97"	"1967.02"	"24.81"	"4"	"5"	"other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00412"	"2273"	"ENSG00000022267"	"FHL1"	"B7Z5T4; B7Z793; hsa:2273; O95212; Q13230; Q13642; Q13645; Q5JXI7; Q5M7Y6; Q6IB30; Q9NZ40; Q9UKZ8; Q9Y630"	"Notch signaling pathway"	""	"1"	"0"	"1197.6"	"944.9"	"1018.0"	"1042.0"	"930.7"	"852.0"	"1303.8"	"1811.5"	"1653.7"	"2584.1"	"2642.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P56192"	"Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2"	"0.000"	""	"9"	"6"	"13"	"6"	"900"	"101.1"	"6.16"	"2288.31"	"24.79"	"5"	"6"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00043, Pf00458, Pf09334, Pf18485, Pf19303"	"4141"	"ENSG00000166986"	"MARS1"	"B3KVK7; hsa:4141; P56192; Q14895; Q53H14; Q96A15; Q96BZ0; Q9NSE0"	""	"Cytosolic tRNA aminoacylation; Selenoamino acid metabolism"	"2"	"0"	"194.4"	"168.6"	"175.6"	"181.5"	"157.5"	"166.3"	"211.8"	"491.0"	"563.2"	"1505.3"	"2282.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09661"	"U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2"	"0.000"	""	"31"	"7"	"14"	"7"	"255"	"28.4"	"8.62"	"3007.28"	"24.67"	"6"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf14580"	"6627"	"ENSG00000131876"	"SNRPA1"	"B2R5I6; hsa:6627; P09661; Q8TBD2"	"mRNA processing"	"mRNA Splicing - Major Pathway; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	"3"	"0"	"934.1"	"966.5"	"725.5"	"744.0"	"747.4"	"733.8"	"974.6"	"1208.4"	"1167.4"	"1915.9"	"2725.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05114"	"Non-histone chromosomal protein HMG-14 OS=Homo sapiens OX=9606 GN=HMGN1 PE=1 SV=3"	"0.000"	""	"55"	"6"	"11"	"6"	"100"	"10.7"	"9.60"	"1342.17"	"24.67"	"3"	"6"	"cell organization and biogenesis;DNA metabolism;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01101"	"3150"	"ENSG00000205581"	"HMGN1"	"hsa:3150; P05114; Q3KQR8"	"ATM signaling in development and disease ; p38 MAPK signaling pathway; Pleural mesothelioma; Nucleotide excision repair in xeroderma pigmentosum"	"Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	"8"	"0"	"662.9"	"524.4"	"598.5"	"588.6"	"606.7"	"634.2"	"767.6"	"944.6"	"822.4"	"895.2"	"759.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P15170"	"Eukaryotic peptide chain release factor GTP-binding subunit ERF3A OS=Homo sapiens OX=9606 GN=GSPT1 PE=1 SV=1"	"0.000"	""	"19"	"9"	"15"	"9"	"499"	"55.7"	"5.62"	"3118.88"	"24.66"	"8"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03143, Pf03144"	"2935"	"ENSG00000103342"	"GSPT1"	"hsa:2935; J3KQG6; P15170; Q96GF2"	""	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"4"	"0"	"199.3"	"138.0"	"297.8"	"241.8"	"252.5"	"245.0"	"274.5"	"1011.1"	"1084.1"	"6550.9"	"8478.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P06730"	"Eukaryotic translation initiation factor 4E OS=Homo sapiens OX=9606 GN=EIF4E PE=1 SV=2"	"0.000"	""	"32"	"6"	"12"	"6"	"217"	"25.1"	"6.15"	"2344.37"	"24.58"	"6"	"6"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01652"	"1977"	"ENSG00000151247"	"EIF4E"	"B7Z6V1; D6RCQ6; hsa:1977; P06730; Q96E95"	"Translation factors; Leptin signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Interleukin-1 (IL-1) structural pathway; Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4); Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; 4-hydroxytamoxifen, dexamethasone, and retinoic acids regulation of p27 expression; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Prader-Willi and Angelman syndrome; PI3K-Akt signaling pathway; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Head and neck squamous cell carcinoma; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; Host-pathogen interaction of human coronaviruses - MAPK signaling; Hypertrophy model; Interferon type I signaling pathways"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Deadenylation of mRNA; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; mTORC1-mediated signalling"	"31"	"0"	"134.4"	"126.3"	"154.4"	"142.0"	"148.9"	"165.6"	"222.1"	"1186.5"	"1277.7"	"3788.4"	"6216.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WW12"	"PEST proteolytic signal-containing nuclear protein OS=Homo sapiens OX=9606 GN=PCNP PE=1 SV=2"	"0.000"	""	"43"	"6"	"12"	"6"	"178"	"18.9"	"7.49"	"2834.37"	"24.56"	"6"	"6"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes"	"nucleus"	""	"Pf15473"	"57092"	"ENSG00000081154"	"PCNP"	"B2RBE7; D3DN52; hsa:57092; Q53GF3; Q6AI44; Q8WW12; Q96CU3; Q9NS81"	""	""	"0"	"0"	"497.7"	"382.0"	"522.4"	"513.1"	"427.0"	"437.2"	"564.5"	"831.7"	"801.6"	"2631.2"	"4476.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q08752"	"Peptidyl-prolyl cis-trans isomerase D OS=Homo sapiens OX=9606 GN=PPID PE=1 SV=3"	"0.000"	""	"21"	"7"	"12"	"6"	"370"	"40.7"	"7.21"	"1807.01"	"24.51"	"4"	"6"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00160, Pf13176"	"5481"	"ENSG00000171497"	"PPID"	"B2R9V2; hsa:5481; Q08752"	"Alzheimer's disease and miRNA effects; NO/cGMP/PKG mediated neuroprotection; Alzheimer's disease"	"ESR-mediated signaling"	"4"	"0"	"194.1"	"166.4"	"225.6"	"204.5"	"193.4"	"207.5"	"253.3"	"781.0"	"860.6"	"2699.2"	"4127.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75369"	"Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2"	"0.000"	""	"4"	"7"	"11"	"6"	"2602"	"278.0"	"5.73"	"1618.97"	"24.51"	"4"	"7"	"cell organization and biogenesis;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00630"	"2317"	"ENSG00000136068"	"FLNB"	"B2ZZ83; B2ZZ84; B2ZZ85; C9JKE6; C9JMC4; hsa:2317; O75369; Q13706; Q59EC2; Q60FE7; Q6MZJ1; Q8WXS9; Q8WXT0; Q8WXT1; Q8WXT2; Q8WXT3; Q9NRB5; Q9NT26; Q9UEV9"	"Focal adhesion; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Ebola virus infection in host; NPHP1 deletion syndrome"	"ISG15 antiviral mechanism"	"6"	"0"	"186.3"	"144.9"	"173.5"	"159.2"	"154.8"	"146.6"	"173.2"	"299.9"	"272.5"	"757.6"	"1508.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11171"	"Protein 4.1 OS=Homo sapiens OX=9606 GN=EPB41 PE=1 SV=4"	"0.000"	""	"11"	"9"	"17"	"8"	"864"	"97.0"	"5.58"	"3341.30"	"24.48"	"9"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf04382, Pf05902, Pf08736, Pf09379, Pf09380"	"2035"	"ENSG00000159023"	"EPB41"	"B1ALH8; B1ALH9; D3DPM9; D3DPN0; hsa:2035; P11171; P11176; Q14245; Q5TB35; Q5VXN8; Q8IXV9; Q9Y578; Q9Y579"	"VEGFA-VEGFR2 signaling; Splicing factor NOVA regulated synaptic proteins; IL-18 signaling pathway"	"Neurexins and neuroligins"	"4"	"0"	"914.9"	"711.0"	"852.0"	"834.4"	"794.3"	"844.5"	"1106.4"	"2147.5"	"2049.4"	"1769.9"	"1886.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23396"	"40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2"	"0.000"	""	"49"	"9"	"15"	"9"	"243"	"26.7"	"9.66"	"2698.03"	"24.46"	"8"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;translational apparatus;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00189, Pf07650"	"6188"	"ENSG00000149273"	"RPS3"	"B2R7N5; hsa:6188; J3KN86; P23396; Q498B5; Q8NI95"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"432.0"	"334.7"	"490.8"	"440.1"	"425.9"	"487.2"	"603.5"	"868.7"	"920.8"	"2025.4"	"2817.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35232"	"Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1"	"0.000"	""	"32"	"7"	"13"	"7"	"272"	"29.8"	"5.76"	"3280.48"	"24.34"	"6"	"6"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01145"	"5245"	"ENSG00000167085"	"PHB1"	"B4DY47; hsa:5245; P35232; Q4VBQ0"	""	"RAF activation; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Processing of SMDT1"	"5"	"0"	"802.4"	"740.0"	"718.6"	"652.1"	"698.1"	"755.1"	"926.4"	"1440.5"	"1524.0"	"3036.1"	"4001.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09012"	"U1 small nuclear ribonucleoprotein A OS=Homo sapiens OX=9606 GN=SNRPA PE=1 SV=3"	"0.000"	""	"12"	"4"	"17"	"2"	"282"	"31.3"	"9.83"	"2613.70"	"24.09"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6626"	"ENSG00000077312"	"SNRPA"	"hsa:6626; P09012"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"1365.1"	"887.7"	"1180.0"	"1201.6"	"1045.3"	"976.8"	"1233.9"	"1312.5"	"1057.9"	"1131.3"	"1654.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q08J23"	"RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2"	"0.000"	""	"9"	"4"	"8"	"4"	"767"	"86.4"	"6.77"	"1380.63"	"24.01"	"2"	"4"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytoskeleton;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01189"	"54888"	"ENSG00000037474"	"NSUN2"	"A8K529; B2RNR4; B3KP09; B4DQW2; G3V1R4; hsa:54888; Q08J23; Q9BVN4; Q9H858; Q9NXD9"	""	"tRNA modification in the nucleus and cytosol"	"1"	"0"	"121.0"	"93.2"	"115.3"	"108.6"	"106.6"	"121.1"	"158.5"	"205.3"	"182.2"	"328.5"	"432.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UK61"	"Protein TASOR OS=Homo sapiens OX=9606 GN=TASOR PE=1 SV=3"	"0.000"	""	"6"	"7"	"12"	"7"	"1670"	"188.9"	"5.80"	"1817.12"	"23.94"	"5"	"7"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf12509"	"23272"	"ENSG00000163946"	"TASOR"	"A1L3A4; B5ME28; hsa:23272; Q9H2F7; Q9UK61; Q9UPP7"	""	""	"0"	"0"	"252.8"	"231.5"	"268.5"	"245.0"	"238.7"	"277.0"	"403.9"	"901.9"	"880.4"	"1915.4"	"2392.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y450"	"HBS1-like protein OS=Homo sapiens OX=9606 GN=HBS1L PE=1 SV=1"	"0.000"	""	"12"	"6"	"12"	"6"	"684"	"75.4"	"6.61"	"2801.16"	"23.90"	"5"	"6"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03143, Pf03144, Pf08938"	"10767"	"ENSG00000112339"	"HBS1L"	"B7Z365; hsa:10767; Q4VX89; Q4VX90; Q5T7G3; Q8NDW9; Q9UPW3; Q9Y450"	""	"mRNA decay by 3' to 5' exoribonuclease"	"1"	"0"	"506.0"	"411.2"	"490.1"	"479.1"	"468.4"	"600.0"	"851.5"	"1937.1"	"1756.8"	"1301.3"	"1141.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62304"	"Small nuclear ribonucleoprotein E OS=Homo sapiens OX=9606 GN=SNRPE PE=1 SV=1"	"0.000"	""	"65"	"4"	"12"	"4"	"92"	"10.8"	"9.44"	"1940.59"	"23.89"	"3"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01423"	"6635"	"ENSG00000182004"	"SNRPE"	"B2R5B9; hsa:6635; P08578; P62304; Q15498; Q5BKT2"	"mRNA processing"	"SARS-CoV-2 modulates host translation machinery; snRNP Assembly; RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"8"	"0"	"281.7"	"227.0"	"264.0"	"269.2"	"227.5"	"228.3"	"320.4"	"413.5"	"420.5"	"811.6"	"1521.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52701"	"DNA mismatch repair protein Msh6 OS=Homo sapiens OX=9606 GN=MSH6 PE=1 SV=2"	"0.000"	""	"7"	"8"	"11"	"8"	"1360"	"152.7"	"6.90"	"842.09"	"23.87"	"3"	"8"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00488, Pf00855, Pf01624, Pf05188, Pf05190, Pf05192"	"2956"	"ENSG00000116062"	"MSH6"	"B4DF41; B4E3I4; F5H2F9; hsa:2956; O43706; O43917; P52701; Q8TCX4; Q9BTB5"	"Glioblastoma signaling pathways; Retinoblastoma gene in cancer; Chromosomal and microsatellite instability in colorectal cancer ; DNA repair pathways, full network; DNA mismatch repair"	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Defective Mismatch Repair Associated With MSH2; Defective Mismatch Repair Associated With MSH6"	"8"	"0"	"416.7"	"337.4"	"464.6"	"441.5"	"385.3"	"415.8"	"531.4"	"921.0"	"911.7"	"2421.0"	"3731.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6PKG0"	"La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2"	"0.000"	""	"9"	"7"	"11"	"7"	"1096"	"123.4"	"8.82"	"2196.57"	"23.79"	"5"	"6"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf05383"	"23367"	"ENSG00000155506"	"LARP1"	"hsa:23367; O94836; Q6PKG0; Q8N4M2; Q8NB73; Q9UFD7"	"Perturbations to host-cell autophagy, induced by SARS-CoV-2 proteins; SARS-CoV-2 innate immunity evasion and cell-specific immune response; Network map of SARS-CoV-2 signaling pathway"	"SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"4"	"0"	"478.5"	"386.3"	"488.5"	"476.4"	"477.0"	"459.7"	"580.0"	"818.0"	"830.6"	"1633.9"	"2194.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TAQ2"	"SWI/SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1"	"0.000"	""	"7"	"7"	"14"	"5"	"1214"	"132.8"	"5.69"	"2841.90"	"23.77"	"7"	"5"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00249, Pf04433, Pf16495, Pf16496, Pf16498"	"6601"	"ENSG00000139613"	"SMARCC2"	"F8VTJ5; hsa:6601; Q59GV3; Q8TAQ2; Q92923; Q96E12; Q96GY4"	"Androgen receptor network in prostate cancer; Tumor suppressor activity of SMARCB1; Thermogenesis; Kleefstra syndrome; 10q11.21q11.23 copy number variation syndrome"	"RMTs methylate histone arginines; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"	"7"	"0"	"330.7"	"303.1"	"309.7"	"313.0"	"304.2"	"306.9"	"399.0"	"627.9"	"597.9"	"1363.7"	"2149.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5SW79"	"Centrosomal protein of 170 kDa OS=Homo sapiens OX=9606 GN=CEP170 PE=1 SV=1"	"0.000"	""	"5"	"7"	"15"	"6"	"1584"	"175.2"	"7.11"	"2686.79"	"23.72"	"7"	"6"	""	"cytosol;cytoskeleton;other cell component"	""	"Pf00498, Pf15308"	"9859"	"ENSG00000143702; ENSG00000276725"	"CEP170"	"hsa:9859; O75058; Q5SW77; Q5SW78; Q5SW79; Q7LGA9; Q86W31; Q9UQ08; Q9UQ09"	"Ciliary landscape"	""	"1"	"1"	"773.8"	"648.6"	"803.5"	"775.2"	"735.2"	"765.1"	"976.0"	"1203.7"	"1161.9"	"1892.2"	"2269.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75390"	"Citrate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=CS PE=1 SV=2"	"0.000"	""	"15"	"7"	"16"	"7"	"466"	"51.7"	"8.32"	"3179.98"	"23.71"	"7"	"7"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00285"	"1431"	"ENSG00000062485"	"CS"	"hsa:1431; O75390; Q71UT9; Q7KZH0; Q96FZ8; Q9BWN8"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Fluoroacetic acid toxicity; TCA cycle (aka Krebs or citric acid cycle)"	"Citric acid cycle (TCA cycle); Mitochondrial protein import"	"6"	"0"	"1063.3"	"840.6"	"1006.6"	"944.2"	"889.3"	"941.1"	"1212.7"	"1515.1"	"1457.0"	"2791.1"	"4492.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q06124"	"Tyrosine-protein phosphatase non-receptor type 11 OS=Homo sapiens OX=9606 GN=PTPN11 PE=1 SV=3"	"0.000"	""	"20"	"9"	"17"	"9"	"593"	"68.0"	"7.30"	"4079.13"	"23.65"	"9"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00017, Pf00102"	"5781"	"ENSG00000179295"	"PTPN11"	"A8K1D9; hsa:5781; Q06124; Q96HD7"	"IL-5 signaling pathway; Heart development; IL-1 signaling pathway; Leptin signaling pathway; Prolactin signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; Pilocytic astrocytoma; Androgen receptor network in prostate cancer; B cell receptor signaling pathway; Interleukin-11 signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Alpha 6 beta 4 signaling pathway; IL-3 signaling pathway; Kit receptor signaling pathway; Hepatocyte growth factor receptor signaling; RAC1/PAK1/p38/MMP2 pathway; IL6 signaling pathway; Hepatitis C and hepatocellular carcinoma; VEGFA-VEGFR2 signaling; Embryonic stem cell pluripotency pathways; IL-4 signaling pathway; Ras signaling; EGF/EGFR signaling pathway; Fragile X syndrome; Cancer immunotherapy by CTLA4 blockade; Cancer immunotherapy by PD-1 blockade; Gastrin signaling pathway; Netrin-UNC5B signaling pathway; Insulin signaling; IL-2 signaling pathway; Angiotensin II receptor type 1 pathway; Kallmann syndrome; Orexin receptor pathway; GDNF signaling; Interferon type I signaling pathways; Type II interferon signaling; T-cell receptor signaling pathway"	"PIP3 activates AKT signaling; GPVI-mediated activation cascade; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Platelet sensitization by LDL; CTLA4 inhibitory signaling; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Interleukin-3, Interleukin-5 and GM-CSF signaling; PD-1 signaling; Activation of IRF3, IRF7 mediated by TBK1, IKBKE; Signal regulatory protein family interactions; Constitutive Signaling by Aberrant PI3K in Cancer; RET signaling; PI3K Cascade; Signaling by SCF-KIT; Downstream signal transduction; Tie2 Signaling; Interleukin-6 signaling; Signaling by Leptin; Regulation of IFNG signaling; Regulation of IFNA/IFNB signaling; Signaling by CSF3 (G-CSF); GAB1 signalosome; Signaling by CSF1 (M-CSF) in myeloid cells; PI-3K cascade:FGFR1; FRS-mediated FGFR1 signaling; PI-3K cascade:FGFR2; FRS-mediated FGFR2 signaling; FRS-mediated FGFR3 signaling; PI-3K cascade:FGFR3; FRS-mediated FGFR4 signaling; PI-3K cascade:FGFR4; Activated NTRK2 signals through FRS2 and FRS3; Spry regulation of FGF signaling; MAPK3 (ERK1) activation; MAPK1 (ERK2) activation; Prolactin receptor signaling; Interleukin-20 family signaling; Netrin mediated repulsion signals; Interleukin-37 signaling; PECAM1 interactions; MET activates PTPN11; STAT5 activation downstream of FLT3 ITD mutants; Regulation of RUNX1 Expression and Activity; STAT5 Activation"	"90"	"0"	"270.3"	"195.6"	"289.2"	"270.1"	"283.2"	"275.4"	"356.2"	"1234.7"	"1211.4"	"2657.8"	"3085.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92599"	"Septin-8 OS=Homo sapiens OX=9606 GN=SEPTIN8 PE=1 SV=4"	"0.000"	""	"16"	"6"	"13"	"3"	"483"	"55.7"	"6.28"	"2061.99"	"23.62"	"4"	"5"	"cell cycle OR cell proliferation;other biological processes"	"other membranes;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf00735"	"23176"	"ENSG00000164402"	"SEPTIN8"	"A6NC65; A6NKP6; F6W7K9; hsa:23176; Q8IX36; Q8IX37; Q92599; Q9BVB3"	"22q11.2 copy number variation syndrome"	""	"1"	"0"	"55.0"	"45.3"	"53.8"	"60.8"	"48.5"	"51.4"	"73.3"	"226.1"	"238.6"	"443.8"	"596.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62280"	"40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3"	"0.000"	""	"39"	"7"	"14"	"7"	"158"	"18.4"	"10.30"	"2729.00"	"23.60"	"7"	"7"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00366, Pf16205"	"6205"	"ENSG00000142534"	"RPS11"	"B2R4F5; hsa:6205; P04643; P62280; Q498Y6; Q6IRY0"	"VEGFA-VEGFR2 signaling; IL-18 signaling pathway; Cytoplasmic ribosomal proteins"	"Major pathway of rRNA processing in the nucleolus and cytosol; Regulation of expression of SLITs and ROBOs; SRP-dependent cotranslational protein targeting to membrane; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"21"	"0"	"1006.2"	"741.7"	"1038.6"	"925.3"	"945.6"	"935.9"	"1268.6"	"1493.6"	"1509.9"	"2684.7"	"4136.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25398"	"40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3"	"0.000"	""	"39"	"6"	"10"	"6"	"132"	"14.5"	"7.21"	"2074.22"	"23.54"	"4"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01248"	"6206"	"ENSG00000112306"	"RPS12"	"hsa:6206; P25398; Q76M58"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"564.2"	"470.2"	"553.7"	"489.0"	"508.7"	"422.0"	"733.1"	"1266.1"	"1191.3"	"3432.4"	"6367.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UII2"	"ATPase inhibitor, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5IF1 PE=1 SV=1"	"0.000"	""	"42"	"7"	"16"	"7"	"106"	"12.2"	"9.35"	"2612.11"	"23.50"	"6"	"7"	"cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"mitochondrion;other cell component"	"enzyme regulator activity;other molecular function"	"Pf04568"	"93974"	"ENSG00000130770; ENSG00000285390"	"ATP5IF1"	"hsa:93974; Q5JXL8; Q6IAQ7; Q9BSL9; Q9UII2"	"Electron transport chain: OXPHOS system in mitochondria"	""	"1"	"0"	"1667.1"	"1570.2"	"1404.9"	"1366.1"	"1278.3"	"1309.7"	"1721.7"	"2634.8"	"2469.0"	"4606.4"	"5617.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22033"	"Methylmalonyl-CoA mutase, mitochondrial OS=Homo sapiens OX=9606 GN=MMUT PE=1 SV=4"	"0.000"	""	"12"	"6"	"10"	"6"	"750"	"83.1"	"6.93"	"1494.62"	"23.49"	"4"	"6"	"other metabolic processes;developmental processes;other biological processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf01642, Pf02310"	"4594"	"ENSG00000146085"	"MMUT"	"A8K953; hsa:4594; P22033; Q5SYZ3; Q96B11; Q9UD64"	"Vitamin B12 metabolism; Amino acid metabolism"	"Propionyl-CoA catabolism; Defective MMAA causes MMA, cblA type; Defective MUT causes MMAM; Cobalamin (Cbl) metabolism"	"6"	"0"	"105.8"	"77.2"	"252.6"	"112.1"	"141.2"	"138.2"	"200.9"	"630.3"	"597.0"	"1382.4"	"2182.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99543"	"DnaJ homolog subfamily C member 2 OS=Homo sapiens OX=9606 GN=DNAJC2 PE=1 SV=4"	"0.000"	""	"13"	"7"	"14"	"7"	"621"	"72.0"	"8.70"	"2419.59"	"23.45"	"7"	"7"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"translation activity;other molecular function"	"Pf00226, Pf00249, Pf16717"	"27000"	"ENSG00000105821"	"DNAJC2"	"A4VCI0; hsa:27000; Q99543; Q9BVX1"	""	"Regulation of HSF1-mediated heat shock response"	"1"	"0"	"481.9"	"386.5"	"468.4"	"419.1"	"436.8"	"436.7"	"546.1"	"1341.4"	"1280.7"	"2917.1"	"3458.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKF6"	"Cleavage and polyadenylation specificity factor subunit 3 OS=Homo sapiens OX=9606 GN=CPSF3 PE=1 SV=1"	"0.000"	""	"13"	"7"	"14"	"7"	"684"	"77.4"	"5.60"	"2965.33"	"23.45"	"7"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00753, Pf07521, Pf10996, Pf11718"	"51692"	"ENSG00000119203"	"CPSF3"	"hsa:51692; O14769; Q53RS2; Q96F36; Q9UKF6"	"mRNA processing"	"Transport of Mature mRNA Derived from an Intronless Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"6"	"0"	"477.3"	"347.6"	"455.2"	"446.4"	"414.0"	"482.7"	"575.7"	"937.5"	"1000.8"	"2530.6"	"3939.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55735"	"Protein SEC13 homolog OS=Homo sapiens OX=9606 GN=SEC13 PE=1 SV=3"	"0.000"	""	"21"	"5"	"12"	"5"	"322"	"35.5"	"5.48"	"2404.72"	"23.33"	"5"	"5"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00400"	"6396"	"ENSG00000157020"	"SEC13"	"A8MV37; B4DXJ1; hsa:6396; P55735; Q5BJF0; Q9BRM6; Q9BUG7"	"Sterol regulatory element-binding proteins (SREBP) signaling"	"ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; snRNP Assembly; Separation of Sister Chromatids; HCMV Late Events; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; HCMV Early Events; EML4 and NUDC in mitotic spindle formation; Amino acids regulate mTORC1; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; COPII-mediated vesicle transport; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Postmitotic nuclear pore complex (NPC) reformation"	"40"	"0"	"421.4"	"255.2"	"430.4"	"389.4"	"353.1"	"400.8"	"578.7"	"1085.7"	"1089.3"	"2101.8"	"2626.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92733"	"Proline-rich protein PRCC OS=Homo sapiens OX=9606 GN=PRCC PE=1 SV=1"	"0.000"	""	"11"	"5"	"9"	"4"	"491"	"52.4"	"5.10"	"1565.00"	"23.30"	"4"	"4"	"cell cycle OR cell proliferation;other biological processes"	"nucleus"	""	"Pf10253"	"5546"	"ENSG00000143294"	"PRCC"	"A8K1F7; hsa:5546; O00665; O00724; Q5SZ06; Q92733"	"Type 2 papillary renal cell carcinoma; IL-18 signaling pathway"	"mRNA Splicing - Major Pathway"	"3"	"1"	"647.3"	"542.0"	"642.2"	"627.1"	"595.2"	"555.8"	"694.8"	"924.3"	"838.3"	"1538.9"	"1765.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VT25"	"Serine/threonine-protein kinase MRCK alpha OS=Homo sapiens OX=9606 GN=CDC42BPA PE=1 SV=1"	"0.000"	""	"5"	"8"	"14"	"7"	"1732"	"197.2"	"6.58"	"2326.91"	"23.19"	"7"	"7"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00130, Pf00433, Pf00780, Pf08826, Pf15796"	"8476"	"ENSG00000143776"	"CDC42BPA"	"hsa:8476; O75039; Q59GZ1; Q5H9N9; Q5T797; Q5VT25; Q5VT26; Q5VT27; Q86XX2; Q86XX3; Q99646"	"Male infertility"	"CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RHOJ GTPase cycle"	"5"	"1"	"403.7"	"297.1"	"433.9"	"428.7"	"423.4"	"932.5"	"1489.3"	"2377.0"	"2134.6"	"2372.1"	"2987.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00505"	"Importin subunit alpha-4 OS=Homo sapiens OX=9606 GN=KPNA3 PE=1 SV=2"	"0.000"	""	"11"	"4"	"8"	"3"	"521"	"57.8"	"4.94"	"1434.91"	"23.18"	"3"	"4"	"cell organization and biogenesis;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00514, Pf01749, Pf16186"	"3839"	"ENSG00000102753"	"KPNA3"	"hsa:3839; O00191; O00505; O43195; Q5JVM9; Q8IYQ9; Q96AA7"	""	"ISG15 antiviral mechanism; NS1 Mediated Effects on Host Pathways"	"2"	"1"	"286.1"	"200.8"	"289.8"	"261.2"	"208.4"	"241.7"	"341.4"	"622.7"	"622.5"	"1808.8"	"3146.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UHD8"	"Septin-9 OS=Homo sapiens OX=9606 GN=SEPTIN9 PE=1 SV=2"	"0.000"	""	"9"	"6"	"12"	"6"	"586"	"65.4"	"8.97"	"2513.82"	"22.99"	"6"	"6"	"cell cycle OR cell proliferation;other biological processes"	"cytoskeleton;other cell component"	"other molecular function"	"Pf00735"	"10801"	"ENSG00000184640"	"SEPTIN9"	"A8K2V3; B3KPM0; B4DTL9; B4E0N2; B4E274; B7Z654; hsa:10801; Q96QF3; Q96QF4; Q96QF5; Q9HA04; Q9UG40; Q9UHD8; Q9Y5W4"	""	""	"0"	"0"	"684.7"	"559.7"	"664.4"	"596.6"	"630.7"	"625.0"	"775.0"	"1420.5"	"1401.7"	"2661.8"	"3597.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95232"	"Luc7-like protein 3 OS=Homo sapiens OX=9606 GN=LUC7L3 PE=1 SV=2"	"0.000"	""	"14"	"7"	"15"	"7"	"432"	"51.4"	"9.79"	"2385.11"	"22.96"	"6"	"7"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf03194"	"51747"	"ENSG00000108848"	"LUC7L3"	"B3KN54; D3DTY1; hsa:51747; O95232; Q6PHR9; Q9NUY0; Q9P2S7"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"770.7"	"569.0"	"687.6"	"681.4"	"609.9"	"591.8"	"816.8"	"1800.6"	"1745.2"	"5953.8"	"9353.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62269"	"40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3"	"0.000"	""	"39"	"8"	"17"	"8"	"152"	"17.7"	"10.99"	"3901.55"	"22.92"	"8"	"6"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00416"	"6222"	"ENSG00000096150; ENSG00000223367; ENSG00000226225; ENSG00000231500; ENSG00000235650"	"RPS18"	"hsa:6222; P25232; P62269; Q5SUJ3; Q6IPF8"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"742.4"	"602.5"	"737.1"	"712.1"	"637.3"	"734.1"	"973.1"	"1429.9"	"1372.1"	"2654.5"	"3874.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46776"	"60S ribosomal protein L27a OS=Homo sapiens OX=9606 GN=RPL27A PE=1 SV=2"	"0.000"	""	"34"	"6"	"14"	"6"	"148"	"16.6"	"11.00"	"2773.69"	"22.85"	"5"	"5"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;other cell component"	"other molecular function"	"Pf00828"	"6157"	"ENSG00000166441"	"RPL27A"	"B2R4B3; hsa:6157; P46776"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"677.7"	"499.3"	"794.4"	"664.3"	"631.4"	"636.3"	"912.0"	"1429.6"	"1268.4"	"3639.6"	"6047.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62140"	"Serine/threonine-protein phosphatase PP1-beta catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CB PE=1 SV=3"	"0.000"	""	"20"	"5"	"10"	"1"	"327"	"37.2"	"6.19"	"2289.08"	"22.77"	"5"	"5"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00149, Pf16891"	"5500"	"ENSG00000213639"	"PPP1CB"	"B2R5V4; D6W565; hsa:5500; P37140; P62140; Q5U087; Q6FG45"	"Common pathways underlying drug addiction; Focal adhesion; Hippo-Merlin signaling dysregulation; 22q11.2 copy number variation syndrome; Airway smooth muscle cell contraction; Neuroinflammation and glutamatergic signaling; G13 signaling pathway"	"RHO GTPases activate CIT; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; Triglyceride catabolism; Regulation of PLK1 Activity at G2/M Transition; Circadian Clock; RAF activation; SHOC2 M1731 mutant abolishes MRAS complex function; Gain-of-function MRAS complexes activate RAF signaling; RHO GTPases activate PAKs; Downregulation of TGF-beta receptor signaling"	"18"	"0"	"37.6"	"40.0"	"58.3"	"50.9"	"49.3"	"44.0"	"50.0"	"122.3"	"132.9"	"346.2"	"487.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P43490"	"Nicotinamide phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=NAMPT PE=1 SV=1"	"0.000"	""	"16"	"7"	"12"	"7"	"491"	"55.5"	"7.15"	"1903.74"	"22.69"	"5"	"6"	"cell-cell signaling;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf04095, Pf18127"	"10135"	"ENSG00000105835"	"NAMPT"	"A4D0Q9; A4D0R0; hsa:10135; P43490; Q3KQV0; Q8WW95"	"Adipogenesis; NAD metabolism, sirtuins and aging; NAD+ metabolism; NAD+ biosynthetic pathways; Caloric restriction and aging; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence"	"NPAS4 regulates expression of target genes; BMAL1:CLOCK,NPAS2 activates circadian gene expression; Nicotinamide salvaging"	"9"	"0"	"537.9"	"482.0"	"494.5"	"486.6"	"457.2"	"488.9"	"681.4"	"1354.0"	"1506.6"	"3183.9"	"4307.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86UE4"	"Protein LYRIC OS=Homo sapiens OX=9606 GN=MTDH PE=1 SV=2"	"0.000"	""	"18"	"7"	"12"	"7"	"582"	"63.8"	"9.32"	"2866.58"	"22.57"	"6"	"6"	"signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf15686"	"92140"	"ENSG00000147649"	"MTDH"	"hsa:92140; Q05DH2; Q52QU9; Q6PK07; Q86UE4; Q8TCX3"	"Gastric cancer network 2; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; CCL18 signaling pathway"	""	"3"	"0"	"505.9"	"422.3"	"508.0"	"470.4"	"468.3"	"496.9"	"613.8"	"1213.4"	"1171.9"	"2124.7"	"2191.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99873"	"Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3"	"0.000"	""	"16"	"6"	"8"	"6"	"371"	"42.4"	"5.35"	"995.72"	"22.48"	"2"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13649"	"3276"	"ENSG00000126457"	"PRMT1"	"A0A087X1W2; B4E3C3; G5E9B6; H7C2I1; hsa:3276; Q15529; Q2VP93; Q6LEU5; Q8WUW5; Q99872; Q99873; Q99874; Q9NZ04; Q9NZ05; Q9NZ06"	"Energy metabolism; mRNA processing; Nitric oxide metabolism in cystic fibrosis; 16p11.2 distal deletion syndrome; Interferon type I signaling pathways"	"Estrogen-dependent gene expression; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Extra-nuclear estrogen signaling; RMTs methylate histone arginines; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Maturation of nucleoprotein"	"11"	"0"	"136.9"	"101.1"	"138.1"	"132.8"	"148.6"	"128.2"	"164.3"	"394.4"	"391.7"	"1108.3"	"2242.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NE71"	"ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2"	"0.000"	""	"8"	"6"	"12"	"6"	"845"	"95.9"	"6.80"	"3195.57"	"22.47"	"6"	"4"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00005, Pf12848"	"23"	"ENSG00000204574; ENSG00000206490; ENSG00000225989; ENSG00000231129; ENSG00000232169; ENSG00000236149; ENSG00000236342"	"ABCF1"	"A2BF75; hsa:23; O14897; Q69YP6; Q8NE71"	"IL-18 signaling pathway"	"ABC-family proteins mediated transport"	"2"	"0"	"622.8"	"433.0"	"578.2"	"541.9"	"530.3"	"546.9"	"708.0"	"1015.2"	"951.3"	"1389.4"	"1447.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N3R9"	"MAGUK p55 subfamily member 5 OS=Homo sapiens OX=9606 GN=MPP5 PE=1 SV=3"	"0.000"	""	"13"	"7"	"14"	"7"	"675"	"77.2"	"6.14"	"3615.13"	"22.46"	"7"	"6"	"cell organization and biogenesis;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf00595, Pf00625, Pf02828, Pf07653, Pf09060"	"64398"	"ENSG00000072415"	"PALS1"	"A1L380; hsa:64398; Q7Z631; Q86T98; Q8N3R9; Q8N7I5; Q9H9Q0"	"Epithelial to mesenchymal transition in colorectal cancer; Complement system in neuronal development and plasticity"	"Tight junction interactions; SARS-CoV-2 targets PDZ proteins in cell-cell junction; SARS-CoV-1 targets PDZ proteins in cell-cell junction"	"5"	"0"	"612.2"	"457.0"	"622.8"	"603.2"	"549.0"	"601.1"	"753.3"	"1571.8"	"1518.1"	"3634.4"	"4900.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P37802"	"Transgelin-2 OS=Homo sapiens OX=9606 GN=TAGLN2 PE=1 SV=3"	"0.000"	""	"39"	"5"	"8"	"5"	"199"	"22.4"	"8.25"	"1414.74"	"22.43"	"3"	"5"	"cell organization and biogenesis;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton"	"cytoskeletal activity"	"Pf00307, Pf00402"	"8407"	"ENSG00000158710"	"TAGLN2"	"E9KL39; hsa:8407; P37802; Q5JRQ6; Q5JRQ7; Q6FGI1; Q9BUH5; Q9H4P0"	""	"Platelet degranulation"	"1"	"0"	"92.6"	"69.5"	"108.4"	"111.3"	"103.7"	"89.5"	"109.9"	"218.9"	"221.2"	"693.0"	"1931.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14168"	"MAGUK p55 subfamily member 2 OS=Homo sapiens OX=9606 GN=MPP2 PE=1 SV=3"	"0.000"	""	"13"	"5"	"10"	"4"	"576"	"64.5"	"6.77"	"2096.25"	"22.42"	"5"	"5"	"cell-cell signaling;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	""	"Pf00595, Pf00625, Pf02828, Pf07653"	"4355"	"ENSG00000108852"	"MPP2"	"B4DGE9; B4DRJ0; B7Z3G8; E7EV80; E7EV91; E7EX01; hsa:4355; Q14168; Q53ES9; Q5CZB9; Q9BQJ2"	""	""	"0"	"0"	"52.9"	"39.2"	"55.5"	"55.7"	"47.8"	"43.3"	"61.4"	"300.5"	"296.2"	"1093.9"	"1637.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NZI8"	"Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2"	"0.000"	""	"8"	"4"	"10"	"3"	"577"	"63.4"	"9.20"	"1904.05"	"22.34"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf00076"	"10642"	"ENSG00000159217"	"IGF2BP1"	"C9JT33; hsa:10642; Q9NZI8"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; eIF5A regulation in response to inhibition of the nuclear export system"	"MAPK6/MAPK4 signaling; Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"	"4"	"0"	"295.3"	"250.4"	"304.9"	"268.3"	"277.0"	"270.3"	"335.2"	"509.3"	"487.5"	"909.3"	"1282.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UNE7"	"E3 ubiquitin-protein ligase CHIP OS=Homo sapiens OX=9606 GN=STUB1 PE=1 SV=2"	"0.000"	""	"29"	"7"	"12"	"7"	"303"	"34.8"	"5.87"	"2198.06"	"22.33"	"6"	"6"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf04564, Pf12895, Pf18391"	"10273"	"ENSG00000103266"	"STUB1"	"A2IDB9; hsa:10273; O60526; Q969U2; Q9HBT1; Q9UNE7"	"Androgen receptor signaling pathway; Parkin-ubiquitin proteasomal system pathway"	"Antigen processing: Ubiquitination & Proteasome degradation; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Regulation of TNFR1 signaling; Regulation of necroptotic cell death; Downregulation of ERBB2 signaling; Downregulation of TGF-beta receptor signaling"	"10"	"0"	"394.9"	"314.2"	"367.9"	"351.3"	"345.4"	"348.0"	"459.0"	"857.3"	"779.5"	"2066.9"	"3205.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13217"	"DnaJ homolog subfamily C member 3 OS=Homo sapiens OX=9606 GN=DNAJC3 PE=1 SV=1"	"0.000"	""	"17"	"9"	"14"	"9"	"504"	"57.5"	"6.15"	"2495.23"	"22.29"	"7"	"7"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00226, Pf00515, Pf13181, Pf13432"	"5611"	"ENSG00000102580"	"DNAJC3"	"hsa:5611; Q13217; Q86WT9; Q8N4N2"	"Photodynamic therapy-induced unfolded protein response"	"Neutrophil degranulation; Viral mRNA Translation; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; XBP1(S) activates chaperone genes"	"6"	"0"	"476.1"	"399.4"	"466.1"	"410.9"	"466.2"	"485.1"	"585.1"	"1843.4"	"1890.1"	"4685.6"	"5876.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q06587"	"E3 ubiquitin-protein ligase RING1 OS=Homo sapiens OX=9606 GN=RING1 PE=1 SV=2"	"0.000"	""	"18"	"4"	"8"	"3"	"406"	"42.4"	"5.62"	"1427.65"	"22.25"	"2"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00097, Pf16207"	"6015"	"ENSG00000204227; ENSG00000206287; ENSG00000226788; ENSG00000228520; ENSG00000231115; ENSG00000235107"	"RING1"	"A8JZZ0; hsa:6015; Q06587; Q5JP96; Q5SQW2; Q86V19"	"Pleural mesothelioma; Notch signaling pathway"	"Oxidative Stress Induced Senescence; SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6"	"11"	"0"	"91.5"	"82.3"	"102.0"	"102.4"	"80.4"	"66.4"	"115.9"	"222.1"	"197.4"	"450.4"	"600.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y265"	"RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1 PE=1 SV=1"	"0.000"	""	"17"	"6"	"12"	"6"	"456"	"50.2"	"6.42"	"2117.81"	"22.24"	"6"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf06068, Pf17856"	"8607"	"ENSG00000175792; ENSG00000284901"	"RUVBL1"	"B2R5S0; hsa:8607; P82276; Q1KMR0; Q53HK5; Q53HL7; Q53Y27; Q9BSX9; Q9Y265"	"Gastric cancer network 1; lncRNA in canonical Wnt signaling and colorectal cancer"	"Ub-specific processing proteases; DNA Damage Recognition in GG-NER; UCH proteinases; Deposition of new CENPA-containing nucleosomes at the centromere; Formation of the beta-catenin:TCF transactivating complex; Telomere Extension By Telomerase; HATs acetylate histones"	"9"	"0"	"275.4"	"200.5"	"286.0"	"253.2"	"226.8"	"262.0"	"335.1"	"609.2"	"622.7"	"1633.3"	"2322.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UN86"	"Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2"	"0.000"	""	"14"	"6"	"13"	"6"	"482"	"54.1"	"5.55"	"2233.74"	"22.20"	"5"	"6"	"cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf02136"	"9908"	"ENSG00000138757"	"G3BP2"	"A8K6X1; hsa:9908; O60606; O75149; Q9UN86; Q9UPA1"	""	"SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"1"	"0"	"752.5"	"594.8"	"772.8"	"658.1"	"660.5"	"726.9"	"932.7"	"1182.7"	"1234.7"	"2482.0"	"3809.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"E9PAV3"	"Nascent polypeptide-associated complex subunit alpha, muscle-specific form OS=Homo sapiens OX=9606 GN=NACA PE=1 SV=1"	"0.000"	""	"3"	"5"	"12"	"5"	"2078"	"205.3"	"9.58"	"2353.55"	"22.18"	"5"	"5"	"transport"	"translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01849, Pf19026"	""	"ENSG00000196531"	"NACA"	"E9PAV3"	""	""	"0"	"0"	"122.5"	"82.7"	"144.4"	"109.3"	"126.9"	"129.4"	"160.8"	"309.2"	"317.7"	"1233.9"	"2149.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92614"	"Unconventional myosin-XVIIIa OS=Homo sapiens OX=9606 GN=MYO18A PE=1 SV=3"	"0.000"	""	"4"	"5"	"10"	"5"	"2054"	"233.0"	"6.30"	"2776.84"	"22.03"	"5"	"5"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00063, Pf01576, Pf17820"	"399687"	"ENSG00000196535"	"MYO18A"	"hsa:399687; Q5H9U3; Q5QD01; Q5W9F9; Q5W9G1; Q8IXP8; Q92614"	""	"Signaling by cytosolic FGFR1 fusion mutants; Signaling by FGFR1 in disease; Signaling by FLT3 fusion proteins"	"3"	"0"	"121.8"	"97.0"	"132.0"	"119.5"	"122.4"	"118.9"	"158.8"	"229.5"	"216.4"	"483.3"	"686.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15160"	"DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1"	"0.000"	""	"22"	"6"	"10"	"6"	"346"	"39.2"	"5.50"	"1642.72"	"21.97"	"4"	"6"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01000, Pf01193"	"9533"	"ENSG00000171453"	"POLR1C"	"hsa:9533; O15160; O75395; Q5JTE3"	"Pyrimidine metabolism; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"15"	"0"	"177.0"	"148.9"	"165.7"	"173.1"	"167.8"	"182.7"	"266.5"	"994.0"	"1015.1"	"2451.7"	"3272.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13995"	"Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD2 PE=1 SV=2"	"0.000"	""	"13"	"6"	"12"	"6"	"350"	"37.9"	"8.73"	"1998.97"	"21.94"	"5"	"6"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00763, Pf02882"	"10797"	"ENSG00000065911"	"MTHFD2"	"hsa:10797; P13995; Q53G90; Q53GV5; Q53S36; Q7Z650"	"Folate metabolism; One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways"	"Metabolism of folate and pterines"	"4"	"0"	"668.2"	"434.1"	"688.8"	"621.8"	"542.6"	"577.9"	"755.0"	"1567.1"	"1547.9"	"3656.9"	"4515.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L7X3"	"Serine/threonine-protein kinase TAO1 OS=Homo sapiens OX=9606 GN=TAOK1 PE=1 SV=1"	"0.000"	""	"4"	"4"	"10"	"3"	"1001"	"116.0"	"7.65"	"2347.71"	"21.93"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;cytoskeletal activity;kinase activity;other molecular function"	"Pf00069"	"57551"	"ENSG00000160551"	"TAOK1"	"A2RUT8; B7ZLV6; hsa:57551; Q7L7X3; Q96L75; Q9H2K7; Q9H7S5; Q9P2I6"	"Microtubule cytoskeleton regulation; MAPK signaling pathway"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"8"	"1"	"167.7"	"126.4"	"206.8"	"185.6"	"184.9"	"179.6"	"280.3"	"590.2"	"565.9"	"1018.4"	"1128.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62937"	"Peptidyl-prolyl cis-trans isomerase A OS=Homo sapiens OX=9606 GN=PPIA PE=1 SV=2"	"0.000"	""	"32"	"6"	"11"	"6"	"165"	"18.0"	"7.81"	"2167.17"	"21.89"	"5"	"6"	"cell adhesion;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00160"	"5478"	"ENSG00000196262"	"PPIA"	"A8K220; hsa:5478; P05092; P62937; Q3KQW3; Q567Q0; Q6IBU5; Q96IX3; Q9BRU4; Q9BTY9; Q9UC61"	"Prolactin signaling pathway"	"Neutrophil degranulation; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Budding and maturation of HIV virion; Platelet degranulation ; Basigin interactions; SARS-CoV-1 activates/modulates innate immune responses; Integration of provirus; APOBEC3G mediated resistance to HIV-1 infection; Calcineurin activates NFAT; Binding and entry of HIV virion; Assembly Of The HIV Virion; Uncoating of the HIV Virion; Minus-strand DNA synthesis; Plus-strand DNA synthesis"	"16"	"0"	"409.9"	"295.6"	"570.0"	"388.6"	"340.8"	"331.5"	"431.8"	"612.7"	"505.6"	"1039.2"	"5572.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12872"	"Splicing factor, suppressor of white-apricot homolog OS=Homo sapiens OX=9606 GN=SFSWAP PE=1 SV=3"	"0.000"	""	"5"	"5"	"14"	"5"	"951"	"104.8"	"8.05"	"2376.48"	"21.82"	"5"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf01805, Pf09750"	"6433"	"ENSG00000061936"	"SFSWAP"	"B2RN45; B7ZM97; F5H6B8; hsa:6433; Q12872; Q6PJF7"	"mRNA processing"	""	"1"	"0"	"587.5"	"514.9"	"567.3"	"542.3"	"530.7"	"547.2"	"702.7"	"883.0"	"866.4"	"1484.7"	"1820.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14684"	"Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3"	"0.000"	""	"14"	"6"	"9"	"6"	"758"	"84.4"	"9.76"	"1606.26"	"21.72"	"4"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf05997"	"23076"	"ENSG00000160208"	"RRP1B"	"hsa:23076; Q14684; Q8TBZ4"	""	""	"0"	"0"	"266.9"	"240.3"	"287.0"	"255.8"	"255.5"	"269.6"	"356.0"	"505.2"	"489.9"	"830.7"	"1005.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q01085"	"Nucleolysin TIAR OS=Homo sapiens OX=9606 GN=TIAL1 PE=1 SV=1"	"0.000"	""	"11"	"6"	"12"	"3"	"375"	"41.6"	"7.74"	"2205.52"	"21.72"	"6"	"6"	"cell cycle OR cell proliferation;stress response;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"7073"	"ENSG00000151923"	"TIAL1"	"A8K3T0; A8K4L9; hsa:7073; Q01085"	""	"FGFR2 alternative splicing"	"1"	"3"	"976.6"	"823.9"	"950.0"	"943.6"	"962.4"	"871.4"	"1181.7"	"1441.7"	"1397.3"	"2230.8"	"2892.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60934"	"Nibrin OS=Homo sapiens OX=9606 GN=NBN PE=1 SV=1"	"0.000"	""	"11"	"8"	"12"	"8"	"754"	"84.9"	"6.90"	"2383.23"	"21.59"	"6"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00498, Pf08599, Pf16508"	"4683"	"ENSG00000104320"	"NBN"	"B2R626; B2RNC5; hsa:4683; O60672; O60934; Q32NF7; Q53FM6; Q63HR6; Q7LDM2"	"miRNA regulation of DNA damage response; Homologous recombination; DDX1 as a regulatory component of the Drosha microprocessor; ATM signaling in development and disease ; Breast cancer pathway; DNA repair pathways, full network; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; Primary ovarian insufficiency; DNA damage response"	"Resolution of D-loop Structures through Holliday Junction Intermediates; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; Meiotic recombination; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; DNA Damage/Telomere Stress Induced Senescence; Nonhomologous End-Joining (NHEJ); HDR through MMEJ (alt-NHEJ); Sensing of DNA Double Strand Breaks"	"29"	"0"	"257.9"	"200.7"	"284.4"	"260.5"	"242.1"	"244.6"	"320.3"	"786.4"	"821.1"	"2188.3"	"3614.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H3P2"	"Negative elongation factor A OS=Homo sapiens OX=9606 GN=NELFA PE=1 SV=3"	"0.000"	""	"13"	"5"	"11"	"5"	"528"	"57.2"	"9.03"	"2009.74"	"21.55"	"4"	"5"	"other biological processes"	"cytosol;nucleus"	"other molecular function"	""	"7469"	"ENSG00000185049"	"NELFA"	"A2A2T1; hsa:7469; O95392; Q9H3P2"	"Initiation of transcription and translation elongation at the HIV-1 LTR; 4p16.3 copy number variation"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes"	"16"	"0"	"280.5"	"222.7"	"285.2"	"273.2"	"249.3"	"251.8"	"327.0"	"464.6"	"427.2"	"788.3"	"954.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25098"	"Beta-adrenergic receptor kinase 1 OS=Homo sapiens OX=9606 GN=GRK2 PE=1 SV=2"	"0.000"	""	"11"	"5"	"6"	"5"	"689"	"79.5"	"7.28"	"539.25"	"21.55"	"2"	"4"	"cell-cell signaling;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"signal transduction activity or receptor binding;kinase activity;other molecular function"	"Pf00069, Pf00169, Pf00615"	"156"	"ENSG00000173020"	"GRK2"	"B0ZBE1; hsa:156; P25098; Q13837; Q6GTT3"	"Chemokine signaling pathway; Hedgehog signaling pathway; Hedgehog signaling pathway"	"G alpha (q) signalling events; Activation of SMO; G alpha (s) signalling events; Cargo recognition for clathrin-mediated endocytosis; Calmodulin induced events"	"8"	"0"	"99.8"	"81.3"	"122.7"	"112.0"	"99.7"	"96.9"	"145.9"	"533.7"	"549.0"	"1922.2"	"2297.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49411"	"Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2"	"0.000"	""	"19"	"7"	"12"	"7"	"452"	"49.5"	"7.61"	"2331.61"	"21.53"	"6"	"6"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"676.4"	"590.9"	"570.6"	"579.3"	"516.3"	"606.3"	"727.8"	"1055.6"	"1033.2"	"2334.7"	"3084.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L5N1"	"COP9 signalosome complex subunit 6 OS=Homo sapiens OX=9606 GN=COPS6 PE=1 SV=1"	"0.000"	""	"23"	"6"	"9"	"6"	"327"	"36.1"	"5.73"	"1792.52"	"21.48"	"4"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf01398, Pf13012"	"10980"	"ENSG00000168090"	"COPS6"	"A4D2A3; hsa:10980; O15387; Q7L5N1"	"Nucleotide-binding oligomerization domain (NOD) pathway; Ciliary landscape"	"Neddylation; Formation of TC-NER Pre-Incision Complex; DNA Damage Recognition in GG-NER; Cargo recognition for clathrin-mediated endocytosis"	"6"	"0"	"145.2"	"117.3"	"149.4"	"146.3"	"132.4"	"145.2"	"223.2"	"748.1"	"741.0"	"3045.3"	"5820.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49915"	"GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1"	"0.000"	""	"10"	"4"	"8"	"4"	"693"	"76.7"	"6.87"	"2036.91"	"21.48"	"2"	"4"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf00117, Pf00958, Pf02540"	"8833"	"ENSG00000163655"	"GMPS"	"A8K639; B4DXV7; F8W720; hsa:8833; P49915"	""	"Purine ribonucleoside monophosphate biosynthesis; Azathioprine ADME"	"2"	"0"	"41.5"	"34.8"	"55.2"	"44.5"	"39.9"	"36.5"	"59.2"	"145.1"	"144.7"	"631.0"	"1455.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16658"	"Fascin OS=Homo sapiens OX=9606 GN=FSCN1 PE=1 SV=3"	"0.000"	""	"12"	"5"	"9"	"5"	"493"	"54.5"	"7.24"	"1721.92"	"21.47"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf06268"	"6624"	"ENSG00000075618"	"FSCN1"	"A6NI89; B2RE97; hsa:6624; Q16658; Q96IC5; Q96IH1; Q9BRF1"	"VEGFA-VEGFR2 signaling; Urotensin-II-mediated signaling pathway"	"Interleukin-4 and Interleukin-13 signaling"	"3"	"0"	"61.4"	"41.8"	"65.7"	"63.7"	"50.5"	"51.1"	"81.1"	"148.6"	"176.9"	"1001.1"	"2877.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5X1"	"Sorting nexin-9 OS=Homo sapiens OX=9606 GN=SNX9 PE=1 SV=1"	"0.000"	""	"10"	"5"	"13"	"5"	"595"	"66.6"	"5.58"	"2721.81"	"21.47"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf00018, Pf00787, Pf10456"	"51429"	"ENSG00000130340"	"SNX9"	"hsa:51429; Q9BSI7; Q9BVM1; Q9UJH6; Q9UP20; Q9Y5X1"	""	"Clathrin-mediated endocytosis; Golgi Associated Vesicle Biogenesis"	"2"	"0"	"287.0"	"178.3"	"352.6"	"336.6"	"427.0"	"895.8"	"1598.1"	"2270.0"	"1689.6"	"1712.2"	"1878.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13554"	"Calcium/calmodulin-dependent protein kinase type II subunit beta OS=Homo sapiens OX=9606 GN=CAMK2B PE=1 SV=3"	"0.000"	""	"9"	"5"	"11"	"1"	"666"	"72.6"	"7.27"	"2580.37"	"21.47"	"5"	"4"	"protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;kinase activity;other molecular function"	"Pf00069, Pf08332"	"816"	"ENSG00000058404"	"CAMK2B"	"A4D2K0; A4D2K1; A4D2K2; A4D2K3; A4D2K4; A4D2K5; A4D2K6; hsa:816; O95437; O95438; O95599; Q13554; Q9UGH7; Q9UGH8; Q9UGH9; Q9UNX0; Q9UNX7; Q9UP00; Q9Y5N4; Q9Y6F4"	"Primary focal segmental glomerulosclerosis (FSGS); Myometrial relaxation and contraction pathways; Serotonin and anxiety; NO/cGMP/PKG mediated neuroprotection; Wnt signaling; Non-genomic actions of 1,25 dihydroxyvitamin D3; Synaptic signaling pathways associated with autism spectrum disorder; Fragile X syndrome; Disruption of postsynaptic signaling by CNV; Neuroinflammation and glutamatergic signaling; GDNF signaling; Hippocampal synaptogenesis and neurogenesis; Calcium regulation in cardiac cells; ErbB signaling pathway"	"Signaling by BRAF and RAF1 fusions; Ion transport by P-type ATPases; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; Assembly and cell surface presentation of NMDA receptors; Ion homeostasis; Interferon gamma signaling; RAF activation; Ras activation upon Ca2+ influx through NMDA receptor; Regulation of MECP2 expression and activity; Unblocking of NMDA receptors, glutamate binding and activation; Negative regulation of NMDA receptor-mediated neuronal transmission; Long-term potentiation; Trafficking of AMPA receptors; Phase 0 - rapid depolarisation; HSF1-dependent transactivation; CaMK IV-mediated phosphorylation of CREB; CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde"	"35"	"0"	"163.5"	"152.1"	"154.8"	"157.8"	"140.4"	"145.3"	"191.4"	"362.6"	"336.3"	"732.3"	"920.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12931"	"Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3"	"0.000"	""	"11"	"6"	"12"	"5"	"704"	"80.1"	"8.21"	"2199.12"	"21.42"	"6"	"6"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00183, Pf02518"	"10131"	"ENSG00000126602"	"TRAP1"	"B4DR68; D3DUC8; F5H897; hsa:10131; O43642; O75235; Q12931; Q9UHL5"	"TNF-alpha signaling pathway; Clock-controlled autophagy in bone metabolism"	"Respiratory electron transport"	"3"	"0"	"341.0"	"221.7"	"319.0"	"308.6"	"287.5"	"344.0"	"410.4"	"662.2"	"724.3"	"1430.3"	"1832.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKX7"	"Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2"	"0.000"	""	"16"	"5"	"9"	"5"	"468"	"50.1"	"7.06"	"1958.91"	"21.40"	"4"	"4"	"transport"	"other membranes;nucleus"	""	"Pf00638, Pf08911"	"10762"	"ENSG00000093000"	"NUP50"	"B1AHA4; B2RB15; hsa:10762; O75644; Q8N6V5; Q9NPM9; Q9NPR6; Q9P1K5; Q9UKX7"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; SUMOylation of DNA replication proteins; Regulation of HSF1-mediated heat shock response; ISG15 antiviral mechanism; HCMV Early Events; HCMV Late Events; Transcriptional regulation by small RNAs; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"28"	"0"	"185.7"	"140.6"	"175.7"	"156.0"	"163.0"	"153.9"	"192.0"	"386.9"	"410.5"	"1119.3"	"1599.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H2U2"	"Inorganic pyrophosphatase 2, mitochondrial OS=Homo sapiens OX=9606 GN=PPA2 PE=1 SV=2"	"0.000"	""	"19"	"4"	"7"	"4"	"334"	"37.9"	"7.39"	"1119.40"	"21.37"	"2"	"4"	"other metabolic processes;other biological processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf00719"	"27068"	"ENSG00000138777"	"PPA2"	"B4DLP7; F8WDN9; hsa:27068; I6L9B6; Q4W5E9; Q6PG51; Q8TBW0; Q96E55; Q9H0T0; Q9H2U2; Q9NX37; Q9P033; Q9ULX0"	""	"Mitochondrial tRNA aminoacylation; Pyrophosphate hydrolysis"	"2"	"0"	"59.2"	"49.8"	"86.9"	"78.6"	"71.1"	"78.7"	"76.5"	"218.6"	"232.8"	"1159.8"	"2348.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14974"	"Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2"	"0.000"	""	"8"	"5"	"9"	"5"	"876"	"97.1"	"4.78"	"1682.81"	"21.36"	"4"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;signal transduction;other biological processes"	"non-structural extracellular;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00514, Pf03810"	"3837"	"ENSG00000108424"	"KPNB1"	"B7ZAV6; D3DTT3; hsa:3837; Q14637; Q14974; Q53XN2; Q96J27"	"Sterol regulatory element-binding proteins (SREBP) signaling; 22q11.2 copy number variation syndrome"	"Neutrophil degranulation; Assembly of the ORC complex at the origin of replication; ISG15 antiviral mechanism; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Nuclear import of Rev protein; Interferon alpha/beta signaling; Apoptosis induced DNA fragmentation; Regulation of cholesterol biosynthesis by SREBP (SREBF); SARS-CoV-1 activates/modulates innate immune responses; Initiation of Nuclear Envelope (NE) Reformation; Postmitotic nuclear pore complex (NPC) reformation; Inhibition of nitric oxide production"	"15"	"0"	"226.3"	"160.0"	"240.5"	"236.5"	"219.8"	"226.8"	"311.9"	"603.9"	"715.4"	"1940.0"	"2867.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P41227"	"N-alpha-acetyltransferase 10 OS=Homo sapiens OX=9606 GN=NAA10 PE=1 SV=1"	"0.000"	""	"28"	"5"	"7"	"5"	"235"	"26.4"	"5.64"	"740.38"	"21.26"	"2"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00583"	"8260"	"ENSG00000102030"	"NAA10"	"A6NM98; hsa:8260; P41227"	""	""	"0"	"0"	"99.1"	"61.0"	"129.0"	"114.3"	"122.8"	"104.3"	"129.1"	"480.6"	"452.4"	"2568.5"	"3540.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IWX8"	"Calcium homeostasis endoplasmic reticulum protein OS=Homo sapiens OX=9606 GN=CHERP PE=1 SV=3"	"0.000"	""	"10"	"6"	"9"	"6"	"916"	"103.6"	"9.04"	"1148.37"	"21.24"	"4"	"5"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf01585, Pf01805, Pf04818"	"10523"	"ENSG00000085872"	"CHERP"	"hsa:10523; O00302; Q4G0Y5; Q8IWX8; Q8WU30; Q99492"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"571.9"	"492.6"	"581.5"	"540.6"	"505.1"	"546.8"	"684.1"	"926.5"	"850.3"	"1813.2"	"2542.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6N069"	"N-alpha-acetyltransferase 16, NatA auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA16 PE=1 SV=2"	"0.000"	""	"8"	"6"	"11"	"2"	"864"	"101.4"	"7.87"	"1250.35"	"21.18"	"3"	"6"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity"	"Pf07719, Pf12569"	"79612"	"ENSG00000172766"	"NAA16"	"B0QZ59; hsa:79612; Q5VSP9; Q6N069; Q6P2D5; Q8N5J3; Q8N870"	""	""	"0"	"0"	"32.0"	"33.1"	"36.0"	"26.1"	"30.4"	"46.6"	"65.6"	"177.7"	"210.6"	"395.6"	"420.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P31939"	"Bifunctional purine biosynthesis protein PURH OS=Homo sapiens OX=9606 GN=ATIC PE=1 SV=3"	"0.000"	""	"15"	"8"	"10"	"8"	"592"	"64.6"	"6.71"	"880.06"	"21.18"	"3"	"6"	"other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol"	"other molecular function"	"Pf01808, Pf02142"	"471"	"ENSG00000138363"	"ATIC"	"A8K202; E9PBU3; hsa:471; P31939; Q13856; Q53S28"	"One-carbon metabolism"	"Signaling by ALK fusions and activated point mutants; Purine ribonucleoside monophosphate biosynthesis"	"3"	"0"	"143.1"	"101.2"	"160.1"	"146.5"	"150.4"	"145.9"	"181.0"	"387.1"	"379.1"	"1976.7"	"5071.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55036"	"26S proteasome non-ATPase regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMD4 PE=1 SV=1"	"0.000"	""	"16"	"5"	"11"	"5"	"377"	"40.7"	"4.79"	"2302.37"	"21.15"	"5"	"4"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf02809, Pf13519"	"5710"	"ENSG00000159352"	"PSMD4"	"D3DV16; hsa:5710; P55036; Q5VWC5; Q9NS92"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; VEGFA-VEGFR2 signaling; Alzheimer's disease"	"Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Regulation of expression of SLITs and ROBOs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"64"	"0"	"200.1"	"123.7"	"201.6"	"190.1"	"180.9"	"181.7"	"232.4"	"672.4"	"647.8"	"3113.5"	"3984.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23528"	"Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3"	"0.000"	""	"49"	"9"	"14"	"9"	"166"	"18.5"	"8.09"	"3525.61"	"21.13"	"9"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf00241"	"1072"	"ENSG00000172757"	"CFL1"	"B3KUQ1; hsa:1072; P23528; Q53Y87; Q9UCA2"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; VEGFA-VEGFR2 signaling; EGF/EGFR signaling pathway; Envelope proteins and their potential roles in EDMD physiopathology; 7q11.23 copy number variation syndrome; Neuroinflammation and glutamatergic signaling; CCL18 signaling pathway; Regulation of actin cytoskeleton; G13 signaling pathway"	"Regulation of actin dynamics for phagocytic cup formation; EPHB-mediated forward signaling; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Platelet degranulation ; Sema3A PAK dependent Axon repulsion; RHO GTPases Activate ROCKs"	"15"	"0"	"1252.0"	"929.5"	"1349.6"	"1196.1"	"997.5"	"928.2"	"1265.9"	"2205.5"	"1997.2"	"4027.9"	"6617.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q69YN2"	"CWF19-like protein 1 OS=Homo sapiens OX=9606 GN=CWF19L1 PE=1 SV=2"	"0.000"	""	"10"	"4"	"10"	"4"	"538"	"60.6"	"7.24"	"2202.92"	"21.11"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"enzyme regulator activity"	"Pf04676, Pf04677"	"55280"	"ENSG00000095485"	"CWF19L1"	"B4DHX1; D3DR66; hsa:55280; Q5W0I3; Q69YN2; Q96HC3; Q9H865; Q9NV13"	""	""	"0"	"0"	"127.0"	"94.0"	"168.9"	"131.9"	"133.9"	"139.8"	"177.0"	"562.6"	"583.6"	"1320.8"	"1617.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z6Z7"	"E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3"	"0.000"	""	"2"	"5"	"10"	"5"	"4374"	"481.6"	"5.22"	"1036.32"	"21.09"	"2"	"5"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00627, Pf00632, Pf02825, Pf06012, Pf06025, Pf14377"	"10075"	"ENSG00000086758"	"HUWE1"	"hsa:10075; O15029; Q4G2Z2; Q5H961; Q6P4D0; Q7Z6Z7; Q8NG67; Q9BUI0; Q9HCJ4; Q9NSL6; Q9P0A9"	""	"Antigen processing: Ubiquitination & Proteasome degradation; Neutrophil degranulation"	"2"	"0"	"114.1"	"100.1"	"110.2"	"107.7"	"109.7"	"100.5"	"131.6"	"196.0"	"192.6"	"393.8"	"531.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86U42"	"Polyadenylate-binding protein 2 OS=Homo sapiens OX=9606 GN=PABPN1 PE=1 SV=3"	"0.000"	""	"22"	"7"	"13"	"7"	"306"	"32.7"	"5.06"	"2399.16"	"20.98"	"6"	"6"	"RNA metabolism OR transcription;other metabolic processes;transport;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"8106"	"ENSG00000100836"	"PABPN1"	"D3DS49; hsa:8106; O43484; Q86U42"	"mRNA processing"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs; Inhibition of Host mRNA Processing and RNA Silencing"	"6"	"0"	"1067.1"	"843.5"	"1091.7"	"963.9"	"968.1"	"932.4"	"1252.2"	"1540.6"	"1439.4"	"2615.2"	"4148.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NUQ3"	"Gamma-taxilin OS=Homo sapiens OX=9606 GN=TXLNG PE=1 SV=2"	"0.000"	""	"14"	"5"	"10"	"4"	"528"	"60.5"	"7.52"	"1664.12"	"20.93"	"5"	"5"	"cell cycle OR cell proliferation;other biological processes"	"other membranes;cytosol;nucleus"	"other molecular function"	"Pf09728"	"55787"	"ENSG00000086712"	"TXLNG"	"hsa:55787; Q2KQ75; Q5JNZ7; Q9NUQ3; Q9P0X1"	""	""	"0"	"0"	"99.3"	"72.7"	"91.7"	"88.3"	"90.3"	"99.7"	"127.0"	"358.4"	"374.8"	"922.8"	"1130.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q07020"	"60S ribosomal protein L18 OS=Homo sapiens OX=9606 GN=RPL18 PE=1 SV=2"	"0.000"	""	"24"	"5"	"12"	"5"	"188"	"21.6"	"11.72"	"1894.46"	"20.90"	"5"	"5"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf17135"	"6141"	"ENSG00000063177"	"RPL18"	"F8VWC5; hsa:6141; Q07020; Q8WTZ6"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis"	"14"	"0"	"282.2"	"204.7"	"323.7"	"272.0"	"270.9"	"307.2"	"392.6"	"560.7"	"561.4"	"1222.2"	"1816.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVM6"	"DnaJ homolog subfamily C member 17 OS=Homo sapiens OX=9606 GN=DNAJC17 PE=1 SV=1"	"0.000"	""	"24"	"5"	"11"	"5"	"304"	"34.7"	"8.53"	"2442.83"	"20.90"	"5"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf00226"	"55192"	"ENSG00000104129"	"DNAJC17"	"hsa:55192; Q9NVM6"	""	""	"0"	"0"	"128.1"	"74.7"	"158.2"	"144.2"	"141.3"	"133.1"	"184.2"	"439.3"	"460.1"	"1346.8"	"1941.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62241"	"40S ribosomal protein S8 OS=Homo sapiens OX=9606 GN=RPS8 PE=1 SV=2"	"0.000"	""	"36"	"7"	"12"	"7"	"208"	"24.2"	"10.32"	"1460.67"	"20.89"	"5"	"7"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01201"	"6202"	"ENSG00000142937"	"RPS8"	"hsa:6202; P09058; P62241; Q6IRL7"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"790.4"	"756.0"	"722.0"	"686.3"	"712.6"	"709.3"	"958.5"	"1283.2"	"1223.7"	"2349.0"	"3614.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P20042"	"Eukaryotic translation initiation factor 2 subunit 2 OS=Homo sapiens OX=9606 GN=EIF2S2 PE=1 SV=2"	"0.000"	""	"27"	"7"	"14"	"7"	"333"	"38.4"	"5.80"	"3337.05"	"20.85"	"6"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01873"	"8894"	"ENSG00000125977"	"EIF2S2"	"hsa:8894; P20042; Q9BVU0; Q9UJE4"	"Translation factors; Brain-derived neurotrophic factor (BDNF) signaling pathway; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell; Primary ovarian insufficiency"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; ABC-family proteins mediated transport; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK1 (HRI) to heme deficiency; PERK regulates gene expression; Recycling of eIF2:GDP; Response of EIF2AK4 (GCN2) to amino acid deficiency"	"14"	"0"	"1032.2"	"842.1"	"1051.3"	"1000.6"	"987.2"	"1024.5"	"1407.7"	"3654.6"	"3441.9"	"3158.0"	"2641.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N3U4"	"Cohesin subunit SA-2 OS=Homo sapiens OX=9606 GN=STAG2 PE=1 SV=3"	"0.000"	""	"7"	"6"	"10"	"3"	"1231"	"141.2"	"5.43"	"1298.62"	"20.85"	"4"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf08514"	"10735"	"ENSG00000101972"	"STAG2"	"B1AMT5; D3DTF5; hsa:10735; O00540; Q5JTI6; Q68DE9; Q8N3U4; Q9H1N8"	"Cell cycle; Cohesin complex - Cornelia de Lange syndrome"	"Resolution of Sister Chromatid Cohesion; SUMOylation of DNA damage response and repair proteins; Separation of Sister Chromatids; Meiotic synapsis; Estrogen-dependent gene expression; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"9"	"2"	"107.6"	"73.7"	"116.4"	"97.2"	"104.9"	"97.0"	"132.8"	"324.4"	"330.5"	"1222.2"	"1767.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P36578"	"60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5"	"0.000"	""	"12"	"6"	"16"	"6"	"427"	"47.7"	"11.06"	"2955.46"	"20.83"	"6"	"5"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00573, Pf14374"	"6124"	"ENSG00000174444"	"RPL4"	"A8K502; hsa:6124; P36578; P39029; Q4VBR0; Q969Z9"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"945.8"	"814.2"	"967.2"	"839.7"	"850.9"	"926.7"	"1214.2"	"1834.3"	"1692.6"	"4080.2"	"6672.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P18583"	"Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4"	"0.000"	""	"3"	"8"	"15"	"8"	"2426"	"263.7"	"5.64"	"2776.91"	"20.80"	"7"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf01585, Pf14709, Pf17069"	"6651"	"ENSG00000159140"	"SON"	"D3DSF5; D3DSF6; E7ETE8; E7EU67; E7EVW3; E9PFQ2; hsa:6651; O14487; O95981; P18583; Q14120; Q6PKE0; Q9H7B1; Q9P070; Q9P072; Q9UKP9; Q9UPY0"	""	""	"0"	"0"	"734.0"	"615.4"	"809.5"	"705.4"	"694.4"	"734.8"	"865.0"	"1230.3"	"1146.8"	"2731.7"	"4086.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P06899"	"Histone H2B type 1-J OS=Homo sapiens OX=9606 GN=H2BC11 PE=1 SV=3"	"0.000"	""	"35"	"4"	"12"	"1"	"126"	"13.9"	"10.32"	"2259.04"	"20.76"	"4"	"4"	"cell organization and biogenesis;stress response;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125"	"8970"	"ENSG00000124635"	"H2BC11"	"B2R4J4; hsa:8970; O60816; P06899"	""	"E3 ubiquitin ligases ubiquitinate target proteins; Deposition of new CENPA-containing nucleosomes at the centromere; Amyloid fiber formation; Meiotic synapsis; HCMV Late Events; Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; HCMV Early Events; Transcriptional regulation by small RNAs; B-WICH complex positively regulates rRNA expression; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Formation of the beta-catenin:TCF transactivating complex; Oxidative Stress Induced Senescence; HDACs deacetylate histones; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Pre-NOTCH Transcription and Translation; Senescence-Associated Secretory Phenotype (SASP); RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; HATs acetylate histones; RNA Polymerase I Promoter Escape; Meiotic recombination; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Packaging Of Telomere Ends; Condensation of Prophase Chromosomes; DNA Damage/Telomere Stress Induced Senescence; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; Nonhomologous End-Joining (NHEJ); RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis"	"43"	"0"	"90.3"	"133.0"	"58.3"	"72.4"	"59.5"	"75.5"	"114.1"	"251.5"	"225.9"	"577.5"	"1154.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H2P0"	"Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1"	"0.000"	""	"5"	"5"	"10"	"5"	"1102"	"123.5"	"7.34"	"2094.86"	"20.53"	"5"	"5"	"cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00046, Pf19627"	"23394"	"ENSG00000101126"	"ADNP"	"E1P5Y2; hsa:23394; O94881; Q5BKU2; Q9H2P0; Q9UG34"	""	""	"0"	"0"	"415.2"	"306.4"	"424.3"	"383.4"	"369.2"	"349.8"	"464.4"	"568.5"	"560.7"	"1000.4"	"1488.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60814"	"Histone H2B type 1-K OS=Homo sapiens OX=9606 GN=H2BC12 PE=1 SV=3"	"0.000"	""	"36"	"5"	"13"	"2"	"126"	"13.9"	"10.32"	"2878.99"	"20.53"	"5"	"4"	"stress response;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125"	"85236"	"ENSG00000197903"	"H2BC12"	"A8K7P7; hsa:85236; O60814; Q2VPI7"	""	"Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Formation of the beta-catenin:TCF transactivating complex; E3 ubiquitin ligases ubiquitinate target proteins; Amyloid fiber formation; Meiotic synapsis; HCMV Late Events; HCMV Early Events; Transcriptional regulation by small RNAs; Deposition of new CENPA-containing nucleosomes at the centromere; B-WICH complex positively regulates rRNA expression; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Oxidative Stress Induced Senescence; HDACs deacetylate histones; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Pre-NOTCH Transcription and Translation; Senescence-Associated Secretory Phenotype (SASP); RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; HATs acetylate histones; RNA Polymerase I Promoter Escape; Meiotic recombination; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Packaging Of Telomere Ends; Condensation of Prophase Chromosomes; DNA Damage/Telomere Stress Induced Senescence; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; Nonhomologous End-Joining (NHEJ); RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis"	"43"	"5"	"780.2"	"920.9"	"653.6"	"586.2"	"551.8"	"630.6"	"936.8"	"1332.0"	"1363.8"	"2711.6"	"4747.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19387"	"DNA-directed RNA polymerase II subunit RPB3 OS=Homo sapiens OX=9606 GN=POLR2C PE=1 SV=2"	"0.000"	""	"26"	"5"	"9"	"5"	"275"	"31.4"	"4.92"	"1776.61"	"20.46"	"4"	"5"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01000, Pf01193"	"5432"	"ENSG00000102978"	"POLR2C"	"hsa:5432; O15161; P19387"	"Pyrimidine metabolism; Eukaryotic transcription initiation; Primary ovarian insufficiency"	"Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; mRNA Splicing - Major Pathway; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"44"	"0"	"281.9"	"191.9"	"295.0"	"254.4"	"259.4"	"267.3"	"378.0"	"636.0"	"606.7"	"1429.4"	"1932.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08579"	"U2 small nuclear ribonucleoprotein B'' OS=Homo sapiens OX=9606 GN=SNRPB2 PE=1 SV=1"	"0.000"	""	"18"	"5"	"15"	"3"	"225"	"25.5"	"9.72"	"2344.54"	"20.46"	"5"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6629"	"ENSG00000125870"	"SNRPB2"	"B2R7J3; D3DW21; hsa:6629; P08579; Q9UJD4"	"mRNA processing; Ciliary landscape"	"mRNA Splicing - Major Pathway"	"3"	"3"	"1812.2"	"1373.5"	"1668.2"	"1566.1"	"1490.5"	"1470.9"	"1929.4"	"2360.6"	"2074.4"	"3462.1"	"4675.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99623"	"Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2"	"0.000"	""	"23"	"7"	"14"	"7"	"299"	"33.3"	"9.83"	"2960.88"	"20.41"	"7"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01145"	"11331"	"ENSG00000215021"	"PHB2"	"B4DP75; hsa:11331; Q2YDA4; Q7KYU3; Q92978; Q99623"	""	"Processing of SMDT1"	"1"	"0"	"809.7"	"778.5"	"779.5"	"706.0"	"758.1"	"780.4"	"975.8"	"1435.6"	"1416.2"	"2737.2"	"3490.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q00535"	"Cyclin-dependent-like kinase 5 OS=Homo sapiens OX=9606 GN=CDK5 PE=1 SV=3"	"0.000"	""	"24"	"6"	"12"	"6"	"292"	"33.3"	"7.66"	"2381.75"	"20.37"	"5"	"5"	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;kinase activity;other molecular function"	"Pf00069"	"1020"	"ENSG00000164885"	"CDK5"	"A1XKG3; hsa:1020; Q00535"	"miRNA regulation of DNA damage response; Nicotine effect on dopaminergic neurons; Alzheimer's disease and miRNA effects; Brain-derived neurotrophic factor (BDNF) signaling pathway; ATM signaling in development and disease ; Alzheimer's disease; Neurogenesis regulation in the olfactory epithelium; DNA damage response"	"DARPP-32 events; NPAS4 regulates expression of target genes; NGF-stimulated transcription; Regulation of TP53 Activity through Phosphorylation; Factors involved in megakaryocyte development and platelet production; CRMPs in Sema3A signaling; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models; Activated NTRK2 signals through CDK5"	"16"	"0"	"109.5"	"85.6"	"117.2"	"118.3"	"124.5"	"267.8"	"470.4"	"1132.8"	"1212.8"	"2786.6"	"4468.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5T8P6"	"RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3"	"0.000"	""	"6"	"6"	"12"	"5"	"1007"	"113.5"	"9.16"	"2403.83"	"20.36"	"6"	"6"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf01480"	"64062"	"ENSG00000139746"	"RBM26"	"B4DZE0; hsa:64062; Q2NKM2; Q2NKQ2; Q5CZH8; Q5T8P5; Q5T8P6; Q5T8P8; Q5U5P5; Q5W0G7; Q8N3H5; Q96K92; Q96SZ3; Q9H2F8; Q9H7F9; Q9P1G7"	""	""	"0"	"1"	"363.5"	"291.0"	"377.8"	"368.6"	"363.7"	"324.3"	"444.7"	"760.6"	"732.7"	"1807.8"	"2469.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16637"	"Survival motor neuron protein OS=Homo sapiens OX=9606 GN=SMN1 PE=1 SV=1"	"0.000"	""	"15"	"5"	"10"	"5"	"294"	"31.8"	"6.55"	"1545.30"	"20.32"	"3"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06003"	"6606; 6607"	"ENSG00000172062; ENSG00000205571; ENSG00000273772; ENSG00000275349; ENSG00000277773"	"SMN1; SMN2"	"A8K0V4; hsa:6606; hsa:6607; Q13119; Q16637; Q549U5; Q96J51"	""	"SARS-CoV-2 modulates host translation machinery; snRNP Assembly"	"2"	"0"	"447.7"	"366.2"	"428.1"	"455.2"	"430.3"	"394.5"	"504.7"	"737.9"	"725.0"	"1438.8"	"1898.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBU8"	"Mortality factor 4-like protein 1 OS=Homo sapiens OX=9606 GN=MORF4L1 PE=1 SV=2"	"0.000"	""	"14"	"5"	"10"	"5"	"362"	"41.4"	"9.28"	"1968.10"	"20.20"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf05712, Pf11717"	"10933"	"ENSG00000185787"	"MORF4L1"	"B4DKN6; B7Z6R1; D3DW88; hsa:10933; O95899; Q5QTS1; Q6NVX8; Q86YT7; Q9HBP6; Q9NSW5; Q9UBU8"	"Pathways affected in adenoid cystic carcinoma"	"HATs acetylate histones"	"2"	"0"	"408.0"	"383.9"	"352.3"	"338.4"	"356.6"	"359.4"	"465.9"	"588.4"	"534.6"	"962.4"	"1272.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O76094"	"Signal recognition particle subunit SRP72 OS=Homo sapiens OX=9606 GN=SRP72 PE=1 SV=3"	"0.000"	""	"11"	"5"	"10"	"5"	"671"	"74.6"	"9.26"	"1398.10"	"20.18"	"3"	"5"	"transport"	"cytosol;ER/Golgi;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf08492, Pf13181, Pf17004"	"6731"	"ENSG00000174780"	"SRP72"	"G5E9Z8; hsa:6731; O76094; Q7Z3C0"	""	"SRP-dependent cotranslational protein targeting to membrane"	"1"	"0"	"58.9"	"41.7"	"68.8"	"68.9"	"60.3"	"61.4"	"82.6"	"161.1"	"145.1"	"424.5"	"890.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30153"	"Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4"	"0.000"	""	"12"	"6"	"12"	"6"	"589"	"65.3"	"5.11"	"2264.15"	"20.12"	"6"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02985"	"5518"	"ENSG00000105568"	"PPP2R1A"	"hsa:5518; P30153; Q13773; Q6ICQ3; Q96DH3"	"Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Wnt signaling pathway and pluripotency; PI3K-Akt signaling pathway; 16p11.2 proximal deletion syndrome; Glycogen synthesis and degradation; Cohesin complex - Cornelia de Lange syndrome"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); RAF activation; Negative regulation of MAPK pathway; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Regulation of TP53 Degradation; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Cyclin D associated events in G1; Disassembly of the destruction complex and recruitment of AXIN to the membrane; Cyclin A/B1/B2 associated events during G2/M transition; Beta-catenin phosphorylation cascade; Signaling by GSK3beta mutants; CTNNB1 S33 mutants aren't phosphorylated; CTNNB1 S37 mutants aren't phosphorylated; CTNNB1 S45 mutants aren't phosphorylated; CTNNB1 T41 mutants aren't phosphorylated; APC truncation mutants have impaired AXIN binding; AXIN missense mutants destabilize the destruction complex; Truncations of AMER1 destabilize the destruction complex; Spry regulation of FGF signaling; MASTL Facilitates Mitotic Progression; Regulation of glycolysis by fructose 2,6-bisphosphate metabolism; Initiation of Nuclear Envelope (NE) Reformation; Platelet sensitization by LDL; CTLA4 inhibitory signaling; Inhibition of replication initiation of damaged DNA by RB1/E2F1; DARPP-32 events; PP2A-mediated dephosphorylation of key metabolic factors; ERKs are inactivated"	"49"	"0"	"470.9"	"350.0"	"465.9"	"443.6"	"384.3"	"431.3"	"584.3"	"1113.1"	"1047.7"	"2472.9"	"3670.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62979"	"Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2"	"0.000"	""	"54"	"7"	"10"	"7"	"156"	"18.0"	"9.64"	"1836.28"	"20.12"	"5"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;translational apparatus;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00240, Pf01599"	"6233"	"ENSG00000143947"	"RPS27A"	"hsa:6233; P02248; P02249; P02250; P14798; P62979; P62988; Q29120; Q6LBL4; Q6LDU5; Q8WYN8; Q91887; Q91888; Q9BQ77; Q9BWD6; Q9BX98; Q9UEF2; Q9UEG1; Q9UEK8; Q9UPK7"	"Cytoplasmic ribosomal proteins"	"Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Aggrephagy; Oxidative Stress Induced Senescence; ISG15 antiviral mechanism; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; InlA-mediated entry of Listeria monocytogenes into host cells; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; Orc1 removal from chromatin; Assembly of the pre-replicative complex; Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; Recognition of DNA damage by PCNA-containing replication complex; Dual Incision in GG-NER; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER; Cargo recognition for clathrin-mediated endocytosis; EGFR downregulation; Negative regulation of MET activity; InlB-mediated entry of Listeria monocytogenes into host cell; Degradation of GLI1 by the proteasome; Hedgehog 'on' state; Activated NOTCH1 Transmits Signal to the Nucleus; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery; FCERI mediated NF-kB activation; Downstream TCR signaling; E3 ubiquitin ligases ubiquitinate target proteins; Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Antigen processing: Ubiquitination & Proteasome degradation; Stimuli-sensing channels; Amyloid fiber formation; Fanconi Anemia Pathway; Budding and maturation of HIV virion; Membrane binding and targetting of GAG proteins; Endosomal Sorting Complex Required For Transport (ESCRT); Late endosomal microautophagy; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Regulation of PLK1 Activity at G2/M Transition; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; NOTCH2 Activation and Transmission of Signal to the Nucleus; NOTCH3 Activation and Transmission of Signal to the Nucleus; Peroxisomal protein import; Regulation of TP53 Degradation; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Activation of IRF3, IRF7 mediated by TBK1, IKBKE; IKK complex recruitment mediated by RIP1; TRAF6-mediated induction of TAK1 complex within TLR4 complex; IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; ER Quality Control Compartment (ERQC); SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Deactivation of the beta-catenin transactivating complex; Circadian Clock; Regulation of signaling by CBL; Metalloprotease DUBs; Regulation of necroptotic cell death; Oncogene Induced Senescence; Cyclin D associated events in G1; APC/C:Cdc20 mediated degradation of Cyclin B; APC-Cdc20 mediated degradation of Nek2A; Senescence-Associated Secretory Phenotype (SASP); Negative regulation of FLT3; Downregulation of ERBB2:ERBB3 signaling; Interferon alpha/beta signaling; Inactivation of CSF3 (G-CSF) signaling; JNK (c-Jun kinases) phosphorylation and  activation mediated by activated human TAK1; Regulation of TP53 Activity through Methylation; Regulation of BACH1 activity; NOD1/2 Signaling Pathway; TICAM1, RIP1-mediated IKK complex recruitment; p75NTR recruits signalling complexes; NF-kB is activated and signals survival; TAK1-dependent IKK and NF-kappa-B activation  ; Regulation of TNFR1 signaling; TNFR1-induced NF-kappa-B signaling pathway; MAP3K8 (TPL2)-dependent MAPK1/3 activation; IRAK1 recruits IKK complex; IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation; Regulation of NF-kappa B signaling; Negative regulators of DDX58/IFIH1 signaling; Prevention of phagosomal-lysosomal fusion; Downregulation of TGF-beta receptor signaling; Downregulation of SMAD2/3:SMAD4 transcriptional activity; Signaling by CSF1 (M-CSF) in myeloid cells; NOTCH1 Intracellular Domain Regulates Transcription; TICAM1-dependent activation of IRF3/IRF7; TICAM1,TRAF6-dependent induction of TAK1 complex; Glycogen synthesis; Formation of TC-NER Pre-Incision Complex; Modulation by Mtb of host immune system; activated TAK1 mediates p38 MAPK activation; IRAK2 mediated activation of TAK1 complex; SARS-CoV-1 activates/modulates innate immune responses; Alpha-protein kinase 1 signaling pathway; Ovarian tumor domain proteases; Spry regulation of FGF signaling; RAS processing; PINK1-PRKN Mediated Mitophagy; Josephin domain DUBs; Regulation of FZD by ubiquitination; Chaperone Mediated Autophagy; Formation of Incision Complex in GG-NER; Iron uptake and transport; VLDLR internalisation and degradation; Myoclonic epilepsy of Lafora; DNA Damage Recognition in GG-NER; Negative regulation of MAPK pathway; TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition); NRIF signals cell death from the nucleus; Assembly Of The HIV Virion; Downregulation of ERBB4 signaling; Regulation of innate immune responses to cytosolic DNA; N-glycan trimming in the ER and Calnexin/Calreticulin cycle; PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1; Regulation of PTEN localization; Pexophagy; Maturation of protein E; Maturation of protein E; FLT3 signaling by CBL mutants; TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling"	"201"	"0"	"1554.2"	"1227.8"	"1442.3"	"1369.5"	"1380.9"	"1291.2"	"1809.8"	"2510.0"	"2310.9"	"4565.3"	"6425.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H3G5"	"Probable serine carboxypeptidase CPVL OS=Homo sapiens OX=9606 GN=CPVL PE=1 SV=2"	"0.000"	""	"9"	"3"	"7"	"3"	"476"	"54.1"	"5.62"	"1133.94"	"20.10"	"2"	"3"	"protein metabolism"	""	"other molecular function"	"Pf00450"	"54504"	"ENSG00000106066"	"CPVL"	"A4D1A4; hsa:54504; Q6UX20; Q8NBL7; Q96AR7; Q9H3G5; Q9HB41"	""	""	"0"	"0"	"72.4"	"55.2"	"76.7"	"75.9"	"70.2"	"86.3"	"108.1"	"342.3"	"377.5"	"1346.8"	"2530.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BY44"	"Eukaryotic translation initiation factor 2A OS=Homo sapiens OX=9606 GN=EIF2A PE=1 SV=3"	"0.000"	""	"14"	"5"	"8"	"5"	"585"	"64.9"	"8.87"	"1172.20"	"20.09"	"3"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;translational apparatus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf08662"	"83939"	"ENSG00000144895"	"EIF2A"	"A8MPS6; B4DF96; B4DQ14; D3DNI9; hsa:83939; Q5QTR2; Q7Z4E9; Q8NFM1; Q96EW9; Q96K81; Q9BY44"	"Photodynamic therapy-induced unfolded protein response; VEGFA-VEGFR2 signaling; 7q11.23 copy number variation syndrome"	""	"3"	"0"	"198.2"	"190.4"	"214.3"	"193.2"	"208.5"	"192.6"	"247.7"	"457.5"	"441.7"	"954.4"	"1079.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75150"	"E3 ubiquitin-protein ligase BRE1B OS=Homo sapiens OX=9606 GN=RNF40 PE=1 SV=5"	"0.000"	""	"5"	"5"	"10"	"3"	"1001"	"113.6"	"6.29"	"2082.59"	"19.89"	"5"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00097"	"9810"	"ENSG00000103549"	"RNF40"	"A0A024QZG0; hsa:9810; O75150; Q6AHZ6; Q6N005; Q7L3T6; Q8N615; Q96T18; Q9BSV9; Q9HC82"	"ATM signaling in development and disease"	"E3 ubiquitin ligases ubiquitinate target proteins"	"2"	"0"	"272.5"	"213.6"	"236.0"	"220.4"	"235.7"	"227.0"	"284.8"	"612.8"	"596.9"	"1313.9"	"1709.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UMR2"	"ATP-dependent RNA helicase DDX19B OS=Homo sapiens OX=9606 GN=DDX19B PE=1 SV=1"	"0.000"	""	"10"	"4"	"7"	"2"	"479"	"53.9"	"6.30"	"1329.18"	"19.75"	"3"	"4"	"other metabolic processes;transport"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"11269"	"ENSG00000157349"	"DDX19B"	"B3KNE9; B4DXS6; E7EMK4; hsa:11269; Q6FIB7; Q6IAE0; Q96KE7; Q9H0U0; Q9UMR2"	""	""	"0"	"2"	"273.6"	"173.8"	"313.3"	"309.1"	"287.8"	"284.4"	"371.4"	"573.4"	"544.2"	"1269.7"	"1596.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EI5"	"Transcription elongation factor A protein-like 4 OS=Homo sapiens OX=9606 GN=TCEAL4 PE=1 SV=2"	"0.000"	""	"35"	"5"	"8"	"5"	"215"	"24.6"	"5.20"	"1004.24"	"19.66"	"3"	"5"	""	"nucleus"	""	"Pf04538"	"79921"	"ENSG00000133142"	"TCEAL4"	"hsa:79921; Q8WY12; Q96EI5; Q9H2H1; Q9H775"	""	""	"0"	"0"	"390.9"	"358.9"	"409.9"	"423.9"	"412.9"	"418.6"	"506.6"	"861.5"	"836.9"	"1295.4"	"1406.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P43246"	"DNA mismatch repair protein Msh2 OS=Homo sapiens OX=9606 GN=MSH2 PE=1 SV=1"	"0.000"	""	"11"	"7"	"11"	"7"	"934"	"104.7"	"5.77"	"1511.83"	"19.61"	"5"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00488, Pf01624, Pf05188, Pf05190, Pf05192"	"4436"	"ENSG00000095002"	"MSH2"	"B4E2Z2; hsa:4436; O75488; P43246"	"RAC1/PAK1/p38/MMP2 pathway; Chromosomal and microsatellite instability in colorectal cancer ; Ciliary landscape; DNA repair pathways, full network; p53 transcriptional gene network; DNA mismatch repair"	"TP53 Regulates Transcription of DNA Repair Genes; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta); Defective Mismatch Repair Associated With MSH3; Defective Mismatch Repair Associated With MSH2; Defective Mismatch Repair Associated With MSH6"	"12"	"0"	"330.2"	"244.3"	"322.8"	"322.4"	"277.4"	"309.0"	"370.6"	"620.1"	"679.1"	"1545.1"	"2276.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14910"	"Protein lin-7 homolog A OS=Homo sapiens OX=9606 GN=LIN7A PE=1 SV=2"	"0.000"	""	"22"	"7"	"15"	"4"	"233"	"26.0"	"8.72"	"3098.57"	"19.50"	"7"	"6"	"cell-cell signaling;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00595, Pf02828"	"8825"	"ENSG00000111052"	"LIN7A"	"A4FTY3; hsa:8825; O14910; Q147W1; Q6LES3; Q7LDS4"	""	"Assembly and cell surface presentation of NMDA receptors; Neurexins and neuroligins; Dopamine Neurotransmitter Release Cycle"	"3"	"0"	"192.6"	"170.6"	"188.7"	"182.5"	"178.0"	"188.5"	"243.7"	"675.2"	"744.3"	"2009.4"	"2861.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3A5"	"Ribosome maturation protein SBDS OS=Homo sapiens OX=9606 GN=SBDS PE=1 SV=4"	"0.000"	""	"24"	"6"	"12"	"6"	"250"	"28.7"	"8.75"	"2474.63"	"19.49"	"6"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;translation activity;nucleic acid binding activity"	"Pf01172, Pf09377, Pf20268"	"51119"	"ENSG00000126524"	"SBDS"	"A8K0P4; hsa:51119; Q96FX0; Q9NV53; Q9Y3A5"	"Genetic causes of porto-sinusoidal vascular disease"	""	"1"	"0"	"756.3"	"551.3"	"650.7"	"604.1"	"636.0"	"685.5"	"900.4"	"2045.6"	"2051.4"	"3627.9"	"3916.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9ULV4"	"Coronin-1C OS=Homo sapiens OX=9606 GN=CORO1C PE=1 SV=1"	"0.000"	""	"18"	"10"	"16"	"10"	"474"	"53.2"	"7.08"	"3783.22"	"19.47"	"10"	"6"	"cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400, Pf08953, Pf16300"	"23603"	"ENSG00000110880"	"CORO1C"	"A7MAP0; A7MAP1; B3KU12; hsa:23603; Q9NSK5; Q9ULV4"	""	""	"0"	"0"	"1147.2"	"906.4"	"999.3"	"909.3"	"968.2"	"983.2"	"1266.7"	"2173.6"	"2034.0"	"4794.9"	"6184.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95292"	"Vesicle-associated membrane protein-associated protein B/C OS=Homo sapiens OX=9606 GN=VAPB PE=1 SV=3"	"0.000"	""	"19"	"4"	"8"	"3"	"243"	"27.2"	"7.30"	"1882.25"	"19.41"	"4"	"4"	"cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00635"	"9217"	"ENSG00000124164"	"VAPB"	"A2A2F2; hsa:9217; O95292; O95293; Q9P0H0"	"Ciliary landscape"	"RHOC GTPase cycle; RHOA GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RHOD GTPase cycle; Sphingolipid de novo biosynthesis"	"7"	"0"	"52.7"	"44.6"	"70.2"	"63.6"	"50.2"	"66.0"	"85.2"	"426.5"	"435.3"	"1356.1"	"2133.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q01130"	"Serine/arginine-rich splicing factor 2 OS=Homo sapiens OX=9606 GN=SRSF2 PE=1 SV=4"	"0.000"	""	"17"	"4"	"8"	"4"	"221"	"25.5"	"11.85"	"1139.76"	"19.36"	"3"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00076"	"6427"	"ENSG00000161547"	"SRSF2"	"B3KWD5; B4DN89; H0YG49; hsa:6427; Q01130"	"mRNA processing"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; mRNA Splicing - Minor Pathway"	"7"	"0"	"429.5"	"355.1"	"408.8"	"374.8"	"367.9"	"390.6"	"484.4"	"658.4"	"538.1"	"1068.5"	"1707.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P36954"	"DNA-directed RNA polymerase II subunit RPB9 OS=Homo sapiens OX=9606 GN=POLR2I PE=1 SV=1"	"0.000"	""	"56"	"5"	"7"	"5"	"125"	"14.5"	"5.14"	"645.57"	"19.33"	"2"	"5"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01096, Pf02150"	"5438"	"ENSG00000105258"	"POLR2I"	"B2R5J2; hsa:5438; P36954; Q6NW05"	"Pyrimidine metabolism; Eukaryotic transcription initiation"	"mRNA Splicing - Major Pathway; Transcriptional regulation by small RNAs; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Inhibition of DNA recombination at telomere; PIWI-interacting RNA (piRNA) biogenesis; Processing of Capped Intron-Containing Pre-mRNA; Viral Messenger RNA Synthesis; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; MicroRNA (miRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Signaling by FGFR2 IIIa TM"	"43"	"0"	"402.4"	"358.3"	"309.5"	"358.5"	"346.4"	"296.5"	"435.5"	"535.7"	"486.5"	"682.9"	"929.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N6M0"	"Deubiquitinase OTUD6B OS=Homo sapiens OX=9606 GN=OTUD6B PE=1 SV=1"	"0.000"	""	"18"	"6"	"10"	"6"	"293"	"33.8"	"6.05"	"1703.46"	"19.31"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	""	"other molecular function"	"Pf02338"	"51633"	"ENSG00000155100"	"OTUD6B"	"A8K6I1; B4DEY0; hsa:51633; Q8N6M0; Q9NTA4; Q9Y387"	"Warburg effect modulated by deubiquitinating enzymes and their substrates"	""	"1"	"0"	"111.1"	"88.6"	"136.2"	"109.9"	"112.2"	"129.9"	"160.8"	"662.3"	"669.0"	"1415.6"	"1388.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P0L0"	"Vesicle-associated membrane protein-associated protein A OS=Homo sapiens OX=9606 GN=VAPA PE=1 SV=3"	"0.000"	""	"26"	"5"	"10"	"4"	"249"	"27.9"	"8.62"	"1957.17"	"19.25"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00635"	"9218"	"ENSG00000101558"	"VAPA"	"A6NDZ0; D3DUI3; hsa:9218; O75453; Q5U0E7; Q9P0L0; Q9UBZ2"	"Exercise-induced circadian regulation; Cholesterol metabolism"	"Neutrophil degranulation; Insertion of tail-anchored proteins into the endoplasmic reticulum membrane; Sphingolipid de novo biosynthesis"	"5"	"1"	"165.1"	"144.4"	"211.6"	"168.7"	"176.6"	"199.5"	"243.0"	"746.2"	"785.8"	"1746.9"	"2547.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NNW5"	"WD repeat-containing protein 6 OS=Homo sapiens OX=9606 GN=WDR6 PE=1 SV=1"	"0.000"	""	"6"	"6"	"12"	"6"	"1121"	"121.6"	"6.87"	"2094.07"	"19.13"	"6"	"6"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf00400"	"11180"	"ENSG00000178252"	"WDR6"	"B4DHK2; hsa:11180; Q3MIT1; Q9NNW5; Q9UF63"	""	"RND2 GTPase cycle; RHOV GTPase cycle; RHOU GTPase cycle; RND3 GTPase cycle; RND1 GTPase cycle"	"5"	"0"	"256.1"	"208.1"	"265.6"	"238.0"	"247.8"	"219.8"	"320.3"	"686.7"	"710.6"	"2084.1"	"3292.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25685"	"DnaJ homolog subfamily B member 1 OS=Homo sapiens OX=9606 GN=DNAJB1 PE=1 SV=4"	"0.000"	""	"21"	"6"	"13"	"5"	"340"	"38.0"	"8.63"	"2575.50"	"19.08"	"6"	"5"	"protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00226, Pf01556"	"3337"	"ENSG00000132002"	"DNAJB1"	"B4DX52; hsa:3337; P25685"	"Nuclear receptors meta-pathway; NRF2 pathway"	"MAPK6/MAPK4 signaling; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Regulation of HSF1-mediated heat shock response; Attenuation phase"	"7"	"1"	"933.8"	"817.4"	"905.7"	"865.6"	"836.6"	"826.1"	"1110.8"	"1440.4"	"1398.6"	"2280.1"	"2898.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35268"	"60S ribosomal protein L22 OS=Homo sapiens OX=9606 GN=RPL22 PE=1 SV=2"	"0.000"	""	"51"	"4"	"8"	"4"	"128"	"14.8"	"9.19"	"1022.51"	"19.07"	"3"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01776"	"6146"	"ENSG00000116251"	"RPL22"	"B2R495; hsa:6146; P35268; Q6IBD1"	"Cytoplasmic ribosomal proteins"	"SRP-dependent cotranslational protein targeting to membrane; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"412.5"	"355.6"	"383.1"	"353.2"	"379.1"	"383.9"	"502.1"	"455.5"	"402.7"	"504.6"	"615.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P68400"	"Casein kinase II subunit alpha OS=Homo sapiens OX=9606 GN=CSNK2A1 PE=1 SV=1"	"0.000"	""	"15"	"5"	"10"	"5"	"391"	"45.1"	"7.74"	"1833.60"	"19.03"	"5"	"5"	"cell-cell signaling;cell cycle OR cell proliferation;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"1457"	"ENSG00000101266"	"CSNK2A1"	"B4DYS6; D3DVV8; hsa:1457; P19138; P20426; P68400; Q14013; Q5U065"	"Alzheimer's disease and miRNA effects; TNF-alpha signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; lncRNA in canonical Wnt signaling and colorectal cancer; Breast cancer pathway; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Translation inhibitors in chronically activated PDGFRA cells; Measles virus infection; Pleural mesothelioma; Alzheimer's disease"	"Regulation of PTEN stability and activity; KEAP1-NFE2L2 pathway; Regulation of TP53 Activity through Phosphorylation; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; WNT mediated activation of DVL; Signal transduction by L1; Receptor Mediated Mitophagy; Condensation of Prometaphase Chromosomes; Synthesis of PC"	"21"	"0"	"201.4"	"166.6"	"219.3"	"203.4"	"201.1"	"208.6"	"273.2"	"463.7"	"448.2"	"1354.5"	"1982.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62750"	"60S ribosomal protein L23a OS=Homo sapiens OX=9606 GN=RPL23A PE=1 SV=1"	"0.000"	""	"49"	"7"	"13"	"7"	"156"	"17.7"	"10.45"	"2749.15"	"18.97"	"6"	"6"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00276, Pf03939"	"6147"	"ENSG00000198242"	"RPL23A"	"B2R5B2; hsa:6147; P29316; P39024; P62750; Q92774"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"866.4"	"774.9"	"819.1"	"735.6"	"773.8"	"799.5"	"1000.4"	"1387.8"	"1374.5"	"2374.2"	"3525.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13555"	"Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sapiens OX=9606 GN=CAMK2G PE=1 SV=4"	"0.000"	""	"13"	"6"	"10"	"2"	"558"	"62.6"	"7.83"	"2651.43"	"18.88"	"6"	"4"	"cell-cell signaling;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf08332"	"818"	"ENSG00000148660"	"CAMK2G"	"A0A0A0MS52; A0A0A0MT11; hsa:818; O00561; O15378; Q13279; Q13282; Q13555; Q13556; Q5SQZ3; Q5SQZ4; Q5SWX4; Q7KYX5; Q8N4I3; Q8NIA4"	"Energy metabolism; Myometrial relaxation and contraction pathways; NO/cGMP/PKG mediated neuroprotection; Splicing factor NOVA regulated synaptic proteins; Wnt signaling; Non-genomic actions of 1,25 dihydroxyvitamin D3; Disruption of postsynaptic signaling by CNV; Neuroinflammation and glutamatergic signaling; Calcium regulation in cardiac cells; ErbB signaling pathway"	"Signaling by BRAF and RAF1 fusions; Ion transport by P-type ATPases; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; Assembly and cell surface presentation of NMDA receptors; Ion homeostasis; Interferon gamma signaling; RAF activation; Ras activation upon Ca2+ influx through NMDA receptor; Regulation of MECP2 expression and activity; Unblocking of NMDA receptors, glutamate binding and activation; Negative regulation of NMDA receptor-mediated neuronal transmission; Long-term potentiation; Trafficking of AMPA receptors; Phase 0 - rapid depolarisation; HSF1-dependent transactivation; CaMK IV-mediated phosphorylation of CREB; CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde"	"31"	"3"	"465.2"	"363.6"	"443.4"	"399.7"	"389.4"	"390.4"	"543.4"	"937.6"	"959.3"	"2428.5"	"3377.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05198"	"Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3"	"0.000"	""	"27"	"8"	"13"	"7"	"315"	"36.1"	"5.08"	"2188.44"	"18.88"	"7"	"6"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf00575, Pf07541"	"1965"	"ENSG00000134001"	"EIF2S1"	"hsa:1965; P05198"	"Translation factors; Alzheimer's disease and miRNA effects; Brain-derived neurotrophic factor (BDNF) signaling pathway; Ebola virus infection in host; Nonalcoholic fatty liver disease; Measles virus infection; Unfolded protein response; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell; Alzheimer's disease"	"ABC-family proteins mediated transport; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK1 (HRI) to heme deficiency; PERK regulates gene expression; Recycling of eIF2:GDP; Response of EIF2AK4 (GCN2) to amino acid deficiency"	"19"	"0"	"312.2"	"262.2"	"267.4"	"273.3"	"260.4"	"306.5"	"414.5"	"1600.0"	"1529.9"	"2610.0"	"2830.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95202"	"Mitochondrial proton/calcium exchanger protein OS=Homo sapiens OX=9606 GN=LETM1 PE=1 SV=1"	"0.000"	""	"9"	"5"	"9"	"5"	"739"	"83.3"	"6.70"	"1355.88"	"18.87"	"4"	"5"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;translation activity;other molecular function"	"Pf07766"	"3954"	"ENSG00000168924"	"LETM1"	"B4DED2; hsa:3954; O95202; Q9UF65"	"4p16.3 copy number variation"	"RHOG GTPase cycle; Mitochondrial calcium ion transport"	"3"	"0"	"267.6"	"208.4"	"281.1"	"255.5"	"267.3"	"261.8"	"343.9"	"661.2"	"683.5"	"1748.3"	"2233.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60841"	"Eukaryotic translation initiation factor 5B OS=Homo sapiens OX=9606 GN=EIF5B PE=1 SV=4"	"0.000"	""	"7"	"6"	"9"	"6"	"1220"	"138.7"	"5.49"	"2232.20"	"18.81"	"5"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03144, Pf11987"	"9669"	"ENSG00000158417"	"EIF5B"	"hsa:9669; O60841; O95805; Q53RV7; Q53SI8; Q9UF81; Q9UMN7"	"Translation factors; Ciliary landscape"	"GTP hydrolysis and joining of the 60S ribosomal subunit"	"3"	"0"	"269.9"	"169.2"	"286.0"	"248.4"	"243.5"	"261.4"	"308.5"	"906.2"	"887.6"	"1863.1"	"2077.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P013"	"Spliceosome-associated protein CWC15 homolog OS=Homo sapiens OX=9606 GN=CWC15 PE=1 SV=2"	"0.000"	""	"25"	"4"	"8"	"4"	"229"	"26.6"	"5.71"	"1286.06"	"18.80"	"3"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity"	"Pf04889"	"51503"	"ENSG00000150316"	"CWC15"	"B2RC17; hsa:51503; Q05BV9; Q05DM1; Q9P013; Q9UI29"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"333.9"	"287.4"	"295.2"	"264.9"	"283.2"	"272.6"	"346.8"	"558.3"	"596.0"	"1680.7"	"2777.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H0G5"	"Nuclear speckle splicing regulatory protein 1 OS=Homo sapiens OX=9606 GN=NSRP1 PE=1 SV=1"	"0.000"	""	"13"	"6"	"12"	"6"	"558"	"66.4"	"8.84"	"2208.01"	"18.77"	"6"	"6"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf09745, Pf20427"	"84081"	"ENSG00000126653"	"NSRP1"	"hsa:84081; Q6FI71; Q9H0G5"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"388.3"	"301.2"	"370.5"	"360.7"	"364.8"	"342.6"	"457.6"	"713.7"	"666.4"	"1308.0"	"1700.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14011"	"Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1"	"0.000"	""	"27"	"3"	"6"	"3"	"172"	"18.6"	"9.51"	"752.49"	"18.69"	"2"	"3"	"cell organization and biogenesis;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"1153"	"ENSG00000099622"	"CIRBP"	"B3KT17; B4E2X2; hsa:1153; Q14011"	""	""	"0"	"0"	"449.5"	"479.2"	"439.8"	"398.8"	"434.9"	"426.9"	"528.5"	"652.2"	"570.1"	"885.5"	"1256.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N1G2"	"Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 OS=Homo sapiens OX=9606 GN=CMTR1 PE=1 SV=1"	"0.000"	""	"8"	"6"	"8"	"6"	"835"	"95.3"	"7.05"	"1255.82"	"18.68"	"3"	"5"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01585, Pf01728"	"23070"	"ENSG00000137200"	"CMTR1"	"A8K949; hsa:23070; Q14670; Q8N1G2; Q96FJ9"	""	""	"0"	"0"	"173.6"	"138.2"	"181.7"	"180.6"	"175.5"	"179.2"	"234.5"	"853.5"	"984.3"	"2109.6"	"2264.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15145"	"Actin-related protein 2/3 complex subunit 3 OS=Homo sapiens OX=9606 GN=ARPC3 PE=1 SV=3"	"0.000"	""	"25"	"5"	"11"	"5"	"178"	"20.5"	"8.59"	"2642.63"	"18.67"	"5"	"5"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf04062"	"10094"	"ENSG00000111229"	"ARPC3"	"hsa:10094; O00554; O15145"	"Pathogenic Escherichia coli infection"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Clathrin-mediated endocytosis; EPHB-mediated forward signaling"	"6"	"0"	"303.0"	"232.7"	"284.1"	"259.5"	"275.4"	"264.4"	"372.2"	"1216.3"	"1271.8"	"2637.9"	"3356.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q02878"	"60S ribosomal protein L6 OS=Homo sapiens OX=9606 GN=RPL6 PE=1 SV=3"	"0.000"	""	"18"	"5"	"12"	"5"	"288"	"32.7"	"10.58"	"2212.21"	"18.65"	"5"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01159, Pf03868"	"6128"	"ENSG00000089009"	"RPL6"	"hsa:6128; Q02878; Q2M3Q3; Q8WW97"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"433.7"	"395.7"	"441.2"	"378.1"	"382.6"	"411.6"	"551.6"	"853.1"	"774.8"	"1747.8"	"2823.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86W42"	"THO complex subunit 6 homolog OS=Homo sapiens OX=9606 GN=THOC6 PE=1 SV=1"	"0.000"	""	"23"	"5"	"9"	"5"	"341"	"37.5"	"7.43"	"1713.06"	"18.60"	"4"	"5"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00400"	"79228"	"ENSG00000131652"	"THOC6"	"B2RA85; hsa:79228; Q86W42; Q8NBR1; Q9BTV9"	""	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript"	"3"	"0"	"347.7"	"290.6"	"295.3"	"293.7"	"274.7"	"266.4"	"381.6"	"613.4"	"573.6"	"1100.3"	"1687.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86YQ8"	"Copine-8 OS=Homo sapiens OX=9606 GN=CPNE8 PE=1 SV=2"	"0.000"	""	"13"	"7"	"11"	"7"	"564"	"63.1"	"5.96"	"1541.53"	"18.57"	"5"	"6"	"other biological processes"	"plasma membrane;other membranes"	"other molecular function"	"Pf00168, Pf07002"	"144402"	"ENSG00000139117"	"CPNE8"	"hsa:144402; Q2TB41; Q86VY2; Q86YQ8"	""	"RHOD GTPase cycle; CDC42 GTPase cycle; RHOQ GTPase cycle; RHOJ GTPase cycle"	"4"	"0"	"159.2"	"124.9"	"155.7"	"159.0"	"153.8"	"149.1"	"190.2"	"550.9"	"567.6"	"2272.5"	"3852.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99496"	"E3 ubiquitin-protein ligase RING2 OS=Homo sapiens OX=9606 GN=RNF2 PE=1 SV=1"	"0.000"	""	"14"	"4"	"9"	"3"	"336"	"37.6"	"6.84"	"1669.90"	"18.56"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf13923, Pf16207"	"6045"	"ENSG00000121481"	"RNF2"	"B2RBS7; B3KRH1; hsa:6045; Q5TEN1; Q5TEN2; Q99496"	"FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; Pleural mesothelioma"	"Oxidative Stress Induced Senescence; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6; SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"	"11"	"1"	"312.0"	"255.6"	"270.2"	"254.3"	"248.2"	"292.8"	"372.8"	"554.4"	"572.7"	"1200.6"	"1755.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62841"	"40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2"	"0.000"	""	"23"	"2"	"7"	"2"	"145"	"17.0"	"10.39"	"929.73"	"18.56"	"1"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00203"	"6209"	"ENSG00000115268"	"RPS15"	"A5D8V9; hsa:6209; P11174; P62841; Q3KRA1; Q9UDC2"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; SRP-dependent cotranslational protein targeting to membrane; Response of EIF2AK4 (GCN2) to amino acid deficiency; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"328.7"	"269.2"	"366.0"	"294.9"	"302.1"	"321.7"	"412.6"	"594.4"	"604.0"	"1186.8"	"1831.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NSD9"	"Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3"	"0.000"	""	"14"	"8"	"13"	"8"	"589"	"66.1"	"6.84"	"2721.30"	"18.54"	"8"	"5"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03483, Pf03484, Pf17759, Pf18262"	"10056"	"ENSG00000116120"	"FARSB"	"B4DFM0; hsa:10056; O95708; Q4ZFX1; Q57ZJ5; Q9NSD9; Q9NZZ6"	"VEGFA-VEGFR2 signaling; Amino acid metabolism"	"Cytosolic tRNA aminoacylation"	"3"	"0"	"605.5"	"390.4"	"501.1"	"469.5"	"515.4"	"540.2"	"665.8"	"1040.1"	"863.9"	"1745.3"	"2310.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95218"	"Zinc finger Ran-binding domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ZRANB2 PE=1 SV=2"	"0.000"	""	"18"	"4"	"8"	"4"	"330"	"37.4"	"10.01"	"2205.77"	"18.52"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00641"	"9406"	"ENSG00000132485"	"ZRANB2"	"D3DQ75; hsa:9406; O95218; Q53GS3; Q59F92; Q5VV33; Q5VV34; Q8IXN6; Q9UP63"	""	""	"0"	"0"	"660.8"	"491.1"	"577.6"	"614.0"	"588.0"	"566.4"	"737.3"	"852.0"	"798.4"	"1152.8"	"1499.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14562"	"Ubiquitin domain-containing protein UBFD1 OS=Homo sapiens OX=9606 GN=UBFD1 PE=1 SV=2"	"0.000"	""	"19"	"5"	"8"	"5"	"309"	"33.4"	"5.77"	"1539.09"	"18.43"	"4"	"4"	""	""	""	"Pf00240"	"56061"	"ENSG00000103353"	"UBFD1"	"A8MW58; D3DWF2; hsa:56061; O14562"	""	""	"0"	"0"	"106.6"	"72.0"	"112.4"	"112.7"	"83.1"	"97.4"	"132.6"	"475.0"	"491.3"	"1881.0"	"2510.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60508"	"Pre-mRNA-processing factor 17 OS=Homo sapiens OX=9606 GN=CDC40 PE=1 SV=1"	"0.000"	""	"13"	"6"	"10"	"6"	"579"	"65.5"	"7.06"	"1560.78"	"18.42"	"5"	"5"	"RNA metabolism OR transcription;other metabolic processes;developmental processes"	"nucleus"	"nucleic acid binding activity"	"Pf00400"	"51362"	"ENSG00000168438"	"CDC40"	"B2RBC5; hsa:51362; O60508; O75471; Q5SRN0; Q9UPG1"	"mRNA processing"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway"	"5"	"0"	"388.4"	"311.6"	"392.3"	"361.0"	"350.9"	"333.5"	"421.5"	"570.3"	"568.1"	"1378.6"	"2504.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BTC0"	"Death-inducer obliterator 1 OS=Homo sapiens OX=9606 GN=DIDO1 PE=1 SV=5"	"0.000"	""	"3"	"4"	"8"	"4"	"2240"	"243.7"	"7.88"	"1891.18"	"18.42"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;signal transduction"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00628, Pf07500, Pf07744"	"11083"	"ENSG00000101191"	"DIDO1"	"A8MY65; B9EH82; E1P5I1; hsa:11083; O15043; Q3ZTL7; Q3ZTL8; Q4VXS1; Q4VXS2; Q4VXV8; Q4VXV9; Q96D72; Q9BQW0; Q9BTC0; Q9BW03; Q9H4G6; Q9H4G7; Q9NTU8; Q9NUM8; Q9UFB6"	""	""	"0"	"0"	"223.5"	"150.0"	"219.4"	"181.4"	"195.3"	"194.5"	"254.3"	"382.5"	"351.0"	"705.1"	"939.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P78344"	"Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1"	"0.000"	""	"9"	"5"	"8"	"5"	"907"	"102.3"	"7.14"	"1081.43"	"18.39"	"3"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus"	"nucleic acid binding activity"	"Pf02020, Pf02847, Pf02854"	"1982"	"ENSG00000110321"	"EIF4G2"	"hsa:1982; O60877; P78344; P78404; Q0VH00; Q0VH01; Q2NKW9; Q49A79; Q53EU1; Q58EZ2; Q8NI71; Q96C16"	"VEGFA-VEGFR2 signaling; Exercise-induced circadian regulation; Acute viral myocarditis"	"ISG15 antiviral mechanism"	"4"	"0"	"195.9"	"125.0"	"202.8"	"201.0"	"171.1"	"197.6"	"225.1"	"384.3"	"379.1"	"692.3"	"877.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99590"	"Protein SCAF11 OS=Homo sapiens OX=9606 GN=SCAF11 PE=1 SV=2"	"0.000"	""	"5"	"9"	"14"	"7"	"1463"	"164.6"	"8.41"	"2954.46"	"18.36"	"9"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	""	"9169"	"ENSG00000139218"	"SCAF11"	"A6NEU9; A6NLW5; hsa:9169; Q8IW59; Q99590"	"Apoptosis"	""	"1"	"2"	"1046.9"	"823.8"	"959.2"	"921.2"	"899.3"	"914.3"	"1274.1"	"2013.7"	"1823.9"	"2976.4"	"3189.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15555"	"Microtubule-associated protein RP/EB family member 2 OS=Homo sapiens OX=9606 GN=MAPRE2 PE=1 SV=1"	"0.000"	""	"11"	"3"	"7"	"3"	"327"	"37.0"	"5.57"	"972.97"	"18.36"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf03271"	"10982"	"ENSG00000166974"	"MAPRE2"	"B2RE21; B3KR39; B4DJV4; B7Z2L3; E9PHR3; F5H1V8; G5E9I6; hsa:10982; Q15555; Q9UQ33"	"Ciliary landscape"	""	"1"	"0"	"52.4"	"42.5"	"67.7"	"65.6"	"62.5"	"54.6"	"76.6"	"344.0"	"340.2"	"884.2"	"944.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62314"	"Small nuclear ribonucleoprotein Sm D1 OS=Homo sapiens OX=9606 GN=SNRPD1 PE=1 SV=1"	"0.000"	""	"37"	"3"	"10"	"3"	"119"	"13.3"	"11.56"	"1786.68"	"18.33"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01423"	"6632"	"ENSG00000167088"	"SNRPD1"	"B5BTZ1; hsa:6632; P13641; P62314"	"mRNA processing"	"mRNA Splicing - Major Pathway; SARS-CoV-2 modulates host translation machinery; snRNP Assembly; mRNA Splicing - Minor Pathway"	"5"	"0"	"93.5"	"102.5"	"129.2"	"92.7"	"89.6"	"102.6"	"119.4"	"190.5"	"191.7"	"353.3"	"686.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P62633"	"Cellular nucleic acid-binding protein OS=Homo sapiens OX=9606 GN=CNBP PE=1 SV=1"	""	""	"18"	"3"	"4"	"3"	"177"	"19.5"	"7.71"	""	"18.31"	""	"3"	"DNA metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00098"	"7555"	"ENSG00000169714"	"CNBP"	"A8K7V4; B2RAV9; B4DP17; D3DNB9; D3DNC0; D3DNC1; E9PDR7; hsa:7555; P20694; P62633; Q4JGY0; Q4JGY1; Q5QJR0; Q5U0E9; Q6PJI7; Q96NV3"	""	"SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"1"	"0"	"194.4"	"242.6"	"122.1"	"139.7"	"140.2"	"76.3"	"185.5"	"447.3"	"385.9"	"831.4"	"808.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P43897"	"Elongation factor Ts, mitochondrial OS=Homo sapiens OX=9606 GN=TSFM PE=1 SV=2"	"0.000"	""	"17"	"5"	"9"	"5"	"325"	"35.4"	"8.38"	"1364.27"	"18.24"	"4"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"mitochondrion;nucleus"	"nucleic acid binding activity"	"Pf00889"	"10102"	"ENSG00000123297"	"TSFM"	"B4E391; F5H2T7; hsa:10102; P43897; Q561V7; Q8TBC2; Q9UQK0"	""	"Mitochondrial translation elongation"	"1"	"0"	"126.4"	"97.0"	"133.0"	"127.5"	"122.6"	"115.2"	"164.6"	"854.2"	"924.3"	"3759.5"	"4779.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P10515"	"Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3"	"0.000"	""	"11"	"5"	"7"	"5"	"647"	"69.0"	"7.84"	"629.11"	"18.20"	"2"	"5"	"other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf00198, Pf00364, Pf02817"	"1737"	"ENSG00000150768"	"DLAT"	"hsa:1737; P10515; Q16783; Q53EP3"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Neuroinflammation and glutamatergic signaling; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"Glyoxylate metabolism and glycine degradation; Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid"	"8"	"0"	"531.2"	"403.1"	"534.9"	"520.5"	"437.7"	"461.9"	"565.9"	"866.6"	"809.2"	"1646.8"	"2459.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5H9R7"	"Serine/threonine-protein phosphatase 6 regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PPP6R3 PE=1 SV=2"	"0.000"	""	"8"	"5"	"8"	"5"	"873"	"97.6"	"4.60"	"990.52"	"18.17"	"3"	"5"	"other biological processes"	"plasma membrane;other membranes;cytosol;nucleus"	"enzyme regulator activity;other molecular function"	"Pf04499"	"55291"	"ENSG00000110075"	"PPP6R3"	"hsa:55291; Q3B7I1; Q3I4Y0; Q3KR35; Q5H9R7; Q68CR3; Q7L4R8; Q8N3B2; Q96MB2; Q9H2K5; Q9H2K6; Q9HCL4; Q9NUY3"	""	"Telomere Extension By Telomerase; COPII-mediated vesicle transport"	"2"	"0"	"386.0"	"282.7"	"396.3"	"360.4"	"343.5"	"327.2"	"466.8"	"769.2"	"784.6"	"1500.1"	"1966.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94905"	"Erlin-2 OS=Homo sapiens OX=9606 GN=ERLIN2 PE=1 SV=1"	"0.000"	""	"19"	"6"	"10"	"6"	"339"	"37.8"	"5.62"	"2112.99"	"18.15"	"5"	"5"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf01145"	"11160"	"ENSG00000147475"	"ERLIN2"	"A0JLQ1; A8K5S9; B4DM38; D3DSW0; hsa:11160; O94905; Q6NW21; Q86VS6; Q86W49"	""	"ABC-family proteins mediated transport; Defective CFTR causes cystic fibrosis; Signaling by FGFR1 in disease; Signaling by plasma membrane FGFR1 fusions"	"4"	"0"	"387.4"	"339.1"	"349.4"	"330.3"	"320.9"	"372.3"	"453.5"	"893.0"	"890.4"	"2202.1"	"3105.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99584"	"Protein S100-A13 OS=Homo sapiens OX=9606 GN=S100A13 PE=1 SV=1"	"0.000"	""	"41"	"4"	"6"	"4"	"98"	"11.5"	"6.16"	"710.97"	"18.11"	"2"	"3"	"transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01023"	"6284"	"ENSG00000189171"	"S100A13"	"hsa:6284; Q52PI9; Q6FGF8; Q99584"	""	""	"0"	"0"	"88.0"	"74.7"	"90.2"	"85.6"	"79.2"	"80.4"	"102.6"	"296.8"	"264.2"	"2638.7"	"5394.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5T9A4"	"ATPase family AAA domain-containing protein 3B OS=Homo sapiens OX=9606 GN=ATAD3B PE=1 SV=1"	"0.000"	""	"8"	"5"	"9"	"2"	"648"	"72.5"	"9.20"	"1417.19"	"18.09"	"4"	"5"	"cell organization and biogenesis"	"plasma membrane;other membranes;mitochondrion"	"other molecular function"	"Pf00004, Pf12037"	"83858"	"ENSG00000160072"	"ATAD3B"	"A8K3H1; hsa:83858; Q5T9A4; Q6ZRB5; Q9BUK4; Q9ULE7"	"1p36 copy number variation syndrome"	"Neutrophil degranulation"	"2"	"3"	"337.7"	"320.7"	"308.5"	"282.4"	"313.2"	"316.5"	"412.1"	"592.1"	"617.0"	"1196.3"	"1903.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07196"	"Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3"	"0.000"	""	"13"	"6"	"11"	"5"	"543"	"61.5"	"4.65"	"2109.18"	"18.03"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00038, Pf04732"	"4747"	"ENSG00000277586"	"NEFL"	"B9ZVN2; hsa:4747; P07196; Q16154; Q8IU72"	"Amyotrophic lateral sclerosis (ALS); Physico-chemical features and toxicity-associated pathways; NO/cGMP/PKG mediated neuroprotection; Ciliary landscape; Intracellular trafficking proteins involved in CMT neuropathy; CCL18 signaling pathway"	"Assembly and cell surface presentation of NMDA receptors; RAF/MAP kinase cascade; Ras activation upon Ca2+ influx through NMDA receptor; Unblocking of NMDA receptors, glutamate binding and activation; Negative regulation of NMDA receptor-mediated neuronal transmission; Long-term potentiation"	"12"	"0"	"938.0"	"699.7"	"765.1"	"773.3"	"708.2"	"745.4"	"900.2"	"1132.8"	"1065.4"	"1757.0"	"2372.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14980"	"Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1"	"0.000"	""	"6"	"5"	"10"	"5"	"1071"	"123.3"	"6.06"	"1489.04"	"18.01"	"3"	"5"	"other metabolic processes;transport;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03810, Pf08389, Pf08767, Pf18777, Pf18784, Pf18787"	"7514"	"ENSG00000082898"	"XPO1"	"A6NL14; A8K1K5; D6W5E2; hsa:7514; O14980; Q63HP8; Q68CP3; Q99433"	"eIF5A regulation in response to inhibition of the nuclear export system; 22q11.2 copy number variation syndrome"	"Separation of Sister Chromatids; MAPK6/MAPK4 signaling; NPAS4 regulates expression of target genes; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Rev-mediated nuclear export of HIV RNA; NEP/NS2 Interacts with the Cellular Export Machinery; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Heme signaling; Deactivation of the beta-catenin transactivating complex; Estrogen-dependent nuclear events downstream of ESR-membrane signaling; Downregulation of TGF-beta receptor signaling; HuR (ELAVL1) binds and stabilizes mRNA; Cyclin A/B1/B2 associated events during G2/M transition"	"18"	"0"	"70.1"	"41.3"	"64.4"	"66.6"	"53.9"	"64.0"	"76.8"	"264.9"	"320.9"	"1329.5"	"2006.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13098"	"COP9 signalosome complex subunit 1 OS=Homo sapiens OX=9606 GN=GPS1 PE=1 SV=4"	"0.000"	""	"12"	"5"	"9"	"5"	"491"	"55.5"	"6.74"	"2066.63"	"17.98"	"5"	"4"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf01399, Pf10602"	"2873"	"ENSG00000169727"	"GPS1"	"hsa:2873; Q13098; Q8NA10; Q9BWL1"	""	"Neddylation; Cargo recognition for clathrin-mediated endocytosis; Formation of TC-NER Pre-Incision Complex; RHOBTB1 GTPase cycle; DNA Damage Recognition in GG-NER"	"5"	"0"	"75.3"	"48.7"	"75.7"	"77.7"	"88.6"	"83.1"	"114.5"	"410.0"	"417.5"	"1670.8"	"2875.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00567"	"Nucleolar protein 56 OS=Homo sapiens OX=9606 GN=NOP56 PE=1 SV=4"	"0.000"	""	"12"	"5"	"9"	"5"	"594"	"66.0"	"9.19"	"2015.06"	"17.91"	"5"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01798, Pf08156"	"10528"	"ENSG00000101361"	"NOP56"	"hsa:10528; O00567; Q2M3T6; Q9NQ05"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol; Association of TriC/CCT with target proteins during biosynthesis"	"3"	"0"	"183.7"	"149.2"	"247.7"	"191.8"	"182.7"	"181.7"	"207.1"	"458.1"	"459.1"	"524.9"	"528.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P016"	"Thymocyte nuclear protein 1 OS=Homo sapiens OX=9606 GN=THYN1 PE=1 SV=1"	"0.000"	""	"25"	"6"	"12"	"6"	"225"	"25.7"	"9.25"	"1990.98"	"17.89"	"6"	"6"	""	""	""	"Pf01878"	"29087"	"ENSG00000151500"	"THYN1"	"hsa:29087; Q567Q2; Q9H3L4; Q9HC20; Q9P016"	""	""	"0"	"0"	"768.7"	"669.8"	"818.1"	"755.0"	"777.0"	"828.9"	"1026.6"	"1364.3"	"1203.5"	"1862.8"	"2008.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96A72"	"Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1"	"0.000"	""	"41"	"5"	"9"	"5"	"148"	"17.3"	"6.39"	"1553.26"	"17.89"	"4"	"5"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf02792"	"55110"	"ENSG00000111196"	"MAGOHB"	"hsa:55110; Q96A72"	""	"Regulation of expression of SLITs and ROBOs; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	"6"	"0"	"252.3"	"201.9"	"264.5"	"208.2"	"222.7"	"246.7"	"314.5"	"564.1"	"513.8"	"1416.1"	"2584.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43809"	"Cleavage and polyadenylation specificity factor subunit 5 OS=Homo sapiens OX=9606 GN=NUDT21 PE=1 SV=1"	"0.000"	""	"29"	"8"	"15"	"8"	"227"	"26.2"	"8.82"	"3315.59"	"17.89"	"8"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13869"	"11051"	"ENSG00000167005"	"NUDT21"	"hsa:11051; O43809; Q6IB85; Q6NE84"	"mRNA processing"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"5"	"0"	"1246.4"	"1106.4"	"1089.2"	"947.3"	"1048.9"	"1022.6"	"1383.1"	"2056.5"	"1988.9"	"4083.0"	"6983.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P78332"	"RNA-binding protein 6 OS=Homo sapiens OX=9606 GN=RBM6 PE=1 SV=5"	"0.000"	""	"7"	"5"	"10"	"5"	"1123"	"128.6"	"6.32"	"1575.68"	"17.89"	"4"	"5"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf01585, Pf17780"	"10180"	"ENSG00000004534"	"RBM6"	"B4E0G6; hsa:10180; O60549; O75524; P78332; Q86SS3"	""	""	"0"	"0"	"420.9"	"338.5"	"399.9"	"413.2"	"403.3"	"397.7"	"496.5"	"625.4"	"606.1"	"906.1"	"975.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NWB6"	"Arginine and glutamate-rich protein 1 OS=Homo sapiens OX=9606 GN=ARGLU1 PE=1 SV=1"	"0.000"	""	"20"	"7"	"14"	"7"	"273"	"33.2"	"10.35"	"2463.34"	"17.81"	"7"	"5"	""	"cytosol;mitochondrion;nucleus"	""	"Pf15346"	"55082"	"ENSG00000134884"	"ARGLU1"	"B4E0Y3; hsa:55082; Q5T257; Q6IQ34; Q9NWB6"	""	""	"0"	"0"	"1139.0"	"839.7"	"1072.3"	"1013.7"	"916.3"	"968.6"	"1232.0"	"2454.0"	"2108.2"	"3881.3"	"4897.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13868"	"Exosome complex component RRP4 OS=Homo sapiens OX=9606 GN=EXOSC2 PE=1 SV=2"	"0.000"	""	"17"	"4"	"10"	"4"	"293"	"32.8"	"7.50"	"2240.80"	"17.75"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf14382, Pf15985"	"23404"	"ENSG00000130713"	"EXOSC2"	"A3KFL3; A3KFL4; B4DKK6; hsa:23404; Q13868; Q9NUY4"	"Ciliary landscape"	"ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Major pathway of rRNA processing in the nucleolus and cytosol; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	"7"	"0"	"210.5"	"176.8"	"240.0"	"216.5"	"198.7"	"226.4"	"266.3"	"438.8"	"388.5"	"1150.3"	"1955.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99426"	"Tubulin-folding cofactor B OS=Homo sapiens OX=9606 GN=TBCB PE=1 SV=2"	"0.000"	""	"8"	"2"	"8"	"2"	"244"	"27.3"	"5.15"	"1858.10"	"17.70"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf01302, Pf14560"	"1155"	"ENSG00000105254"	"TBCB"	"hsa:1155; O00111; O00674; O14728; Q6FGY5; Q99426"	""	"Post-chaperonin tubulin folding pathway"	"1"	"0"	"23.3"	"27.1"	"36.5"	"29.5"	"30.2"	"38.7"	"33.7"	"85.5"	"88.7"	"468.6"	"1135.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9C0C2"	"182 kDa tankyrase-1-binding protein OS=Homo sapiens OX=9606 GN=TNKS1BP1 PE=1 SV=4"	"0.000"	""	"6"	"8"	"13"	"8"	"1729"	"181.7"	"4.86"	"2421.21"	"17.67"	"8"	"5"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf15327"	"85456"	"ENSG00000149115"	"TNKS1BP1"	"A7E2F8; hsa:85456; Q6PJ35; Q6ZV74; Q9C0C2"	"Ciliary landscape"	"Deadenylation of mRNA; TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"	"3"	"0"	"324.4"	"289.8"	"366.4"	"364.4"	"328.3"	"323.9"	"377.6"	"619.7"	"636.5"	"1391.3"	"1479.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P18621"	"60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3"	"0.000"	""	"22"	"5"	"11"	"5"	"184"	"21.4"	"10.17"	"1914.32"	"17.59"	"4"	"5"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf00237"	"6139"	"ENSG00000265681"	"RPL17"	"B2R4H3; B4E3C2; B5ME31; hsa:6139; J3QL51; P18621; Q3KQW2; Q6NZ54; Q7M4M5"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"487.1"	"462.8"	"492.0"	"445.5"	"494.3"	"475.8"	"624.2"	"905.3"	"872.5"	"1576.9"	"2351.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P6C2"	"RNA demethylase ALKBH5 OS=Homo sapiens OX=9606 GN=ALKBH5 PE=1 SV=2"	"0.000"	""	"14"	"4"	"6"	"4"	"394"	"44.2"	"9.09"	"1413.02"	"17.55"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;ER/Golgi;nucleus"	"other molecular function"	"Pf13532"	"54890"	"ENSG00000091542"	"ALKBH5"	"B4DVJ4; D3DXC6; hsa:54890; Q6P6C2; Q9NXD6"	"Smith-Magenis and Potocki-Lupski syndrome copy number variation"	"Reversal of alkylation damage by DNA dioxygenases"	"2"	"0"	"242.0"	"213.4"	"201.8"	"236.9"	"220.3"	"218.2"	"294.4"	"360.6"	"332.7"	"547.0"	"664.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13151"	"Heterogeneous nuclear ribonucleoprotein A0 OS=Homo sapiens OX=9606 GN=HNRNPA0 PE=1 SV=1"	"0.000"	""	"17"	"5"	"18"	"3"	"305"	"30.8"	"9.29"	"4379.13"	"17.51"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"10949"	"ENSG00000177733"	"HNRNPA0"	"hsa:10949; Q13151; Q6IB18"	""	""	"0"	"0"	"673.5"	"593.2"	"657.8"	"611.8"	"599.8"	"624.6"	"752.7"	"912.7"	"767.2"	"1297.0"	"1833.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55769"	"NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3"	"0.000"	""	"63"	"6"	"8"	"6"	"128"	"14.2"	"8.46"	"1547.78"	"17.50"	"4"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01248"	"4809"	"ENSG00000100138"	"SNU13"	"hsa:4809; P55769"	"mRNA processing"	"mRNA Splicing - Major Pathway; Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"4"	"0"	"587.9"	"322.8"	"478.0"	"430.4"	"335.2"	"280.1"	"528.3"	"854.4"	"1029.3"	"1694.9"	"2063.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60828"	"Polyglutamine-binding protein 1 OS=Homo sapiens OX=9606 GN=PQBP1 PE=1 SV=1"	"0.000"	""	"23"	"4"	"8"	"4"	"265"	"30.5"	"6.33"	"1937.82"	"17.50"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	""	"10084"	"ENSG00000102103"	"PQBP1"	"C9JQA1; hsa:10084; O60828; Q4VY25; Q4VY26; Q4VY27; Q4VY29; Q4VY30; Q4VY34; Q4VY35; Q4VY36; Q4VY37; Q4VY38; Q9GZP2; Q9GZU4; Q9GZZ4"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"597.1"	"545.2"	"528.2"	"517.6"	"506.8"	"550.8"	"684.9"	"1117.2"	"1060.0"	"2130.4"	"2480.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NW64"	"Pre-mRNA-splicing factor RBM22 OS=Homo sapiens OX=9606 GN=RBM22 PE=1 SV=1"	"0.000"	""	"14"	"5"	"10"	"5"	"420"	"46.9"	"8.54"	"2447.19"	"17.48"	"5"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"55696"	"ENSG00000086589"	"RBM22"	"A6NDM5; B4DLI9; hsa:55696; O95607; Q9NW64"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"760.5"	"742.5"	"639.8"	"591.3"	"657.3"	"672.2"	"878.8"	"1228.4"	"1086.7"	"2182.0"	"3373.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H0C8"	"Integrin-linked kinase-associated serine/threonine phosphatase 2C OS=Homo sapiens OX=9606 GN=ILKAP PE=1 SV=1"	"0.000"	""	"10"	"4"	"9"	"4"	"392"	"42.9"	"7.09"	"1498.16"	"17.47"	"4"	"4"	"protein metabolism;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf00481"	"80895"	"ENSG00000132323"	"ILKAP"	"B3KM39; hsa:80895; Q9H0C8"	"2q37 copy number variation syndrome"	""	"1"	"0"	"166.8"	"131.1"	"165.1"	"149.2"	"141.4"	"140.8"	"183.0"	"1092.8"	"1161.5"	"3247.8"	"4137.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q53F19"	"Nuclear cap-binding protein subunit 3 OS=Homo sapiens OX=9606 GN=NCBP3 PE=1 SV=2"	"0.000"	""	"13"	"7"	"14"	"7"	"620"	"70.5"	"5.73"	"2800.50"	"17.42"	"7"	"5"	"RNA metabolism OR transcription;other metabolic processes;stress response;transport"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf10309"	"55421"	"ENSG00000074356"	"NCBP3"	"B3KWG7; hsa:55421; Q53F19; Q7L406; Q96FK1; Q9NXZ4"	""	""	"0"	"0"	"1163.4"	"1000.0"	"999.1"	"984.9"	"924.8"	"929.7"	"1163.0"	"1745.0"	"1624.1"	"3995.4"	"5719.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96SY0"	"Integrator complex subunit 14 OS=Homo sapiens OX=9606 GN=INTS14 PE=1 SV=2"	"0.000"	""	"11"	"4"	"10"	"4"	"518"	"57.4"	"5.12"	"1943.13"	"17.42"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	"Pf13519, Pf19435, Pf20504"	"81556"	"ENSG00000138614"	"INTS14"	"B4DDI6; B4DVD5; hsa:81556; Q49AH8; Q96HX5; Q96SY0; Q9H0S5"	"1p36 copy number variation syndrome"	"RNA polymerase II transcribes snRNA genes"	"2"	"0"	"55.0"	"36.8"	"40.0"	"48.4"	"46.5"	"48.4"	"67.1"	"134.5"	"160.4"	"402.2"	"633.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15355"	"Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1"	"0.000"	""	"13"	"6"	"13"	"6"	"546"	"59.2"	"4.36"	"2473.83"	"17.40"	"6"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf00481"	"5496"	"ENSG00000115241"	"PPM1G"	"hsa:5496; O15355"	"VEGFA-VEGFR2 signaling; mRNA processing"	""	"2"	"0"	"503.9"	"390.2"	"541.4"	"491.1"	"464.8"	"472.5"	"671.4"	"941.2"	"819.4"	"1585.9"	"2233.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96RP9"	"Elongation factor G, mitochondrial OS=Homo sapiens OX=9606 GN=GFM1 PE=1 SV=2"	"0.000"	""	"5"	"4"	"10"	"4"	"751"	"83.4"	"7.01"	"1917.28"	"17.39"	"4"	"4"	"protein metabolism;other metabolic processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf00679, Pf03144, Pf03764, Pf14492"	"85476"	"ENSG00000168827"	"GFM1"	"A6NCI9; B2RCB9; B3KRW1; hsa:85476; Q6GTN2; Q96RP9; Q96T39"	""	"Mitochondrial translation elongation"	"1"	"0"	"103.9"	"81.0"	"116.5"	"99.9"	"114.1"	"100.7"	"133.5"	"291.7"	"310.5"	"1068.8"	"1474.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99460"	"26S proteasome non-ATPase regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PSMD1 PE=1 SV=2"	"0.000"	""	"6"	"5"	"10"	"5"	"953"	"105.8"	"5.39"	"1996.32"	"17.37"	"5"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf01851, Pf13646, Pf18004"	"5707"	"ENSG00000173692"	"PSMD1"	"B8ZZH9; hsa:5707; Q24JU0; Q53TI2; Q6GMU5; Q6P2P4; Q6PJM7; Q6PKG9; Q86VU1; Q8IV79; Q99460"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"Neutrophil degranulation; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; MAPK6/MAPK4 signaling; The role of GTSE1 in G2/M progression after G2 checkpoint; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"64"	"0"	"441.4"	"306.0"	"421.5"	"406.5"	"356.0"	"359.5"	"477.7"	"597.0"	"545.5"	"1216.5"	"2411.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86YS7"	"C2 domain-containing protein 5 OS=Homo sapiens OX=9606 GN=C2CD5 PE=1 SV=1"	"0.000"	""	"8"	"6"	"9"	"6"	"1000"	"110.4"	"5.69"	"1295.53"	"17.32"	"4"	"5"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00168"	"9847"	"ENSG00000111731"	"C2CD5"	"B4DJ03; B4DRN7; B7ZLL0; F5H2A1; F5H5R1; hsa:9847; O60280; Q17RY7; Q7Z619; Q86SU3; Q86YS7"	""	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"	"1"	"0"	"182.8"	"126.6"	"178.0"	"176.3"	"182.1"	"493.4"	"1016.8"	"1873.7"	"1736.7"	"2497.9"	"2976.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49321"	"Nuclear autoantigenic sperm protein OS=Homo sapiens OX=9606 GN=NASP PE=1 SV=2"	"0.000"	""	"7"	"6"	"11"	"5"	"788"	"85.2"	"4.30"	"2006.78"	"17.28"	"5"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf10516"	"4678"	"ENSG00000132780"	"NASP"	"A8K6H2; B4DQP3; D3DQ07; F5H3J2; hsa:4678; P49321; Q53GW5; Q5T622; Q5T625; Q96A69; Q9BTW2"	""	""	"0"	"0"	"704.6"	"525.3"	"640.4"	"584.9"	"611.3"	"642.3"	"750.9"	"1102.6"	"1019.3"	"1552.0"	"2162.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15126"	"Phosphomevalonate kinase OS=Homo sapiens OX=9606 GN=PMVK PE=1 SV=3"	"0.000"	""	"44"	"8"	"14"	"8"	"192"	"22.0"	"5.73"	"2995.81"	"17.26"	"8"	"6"	"other metabolic processes;other biological processes"	"cytosol;other cytoplasmic organelle"	"kinase activity;other molecular function"	"Pf04275"	"10654"	"ENSG00000163344"	"PMVK"	"hsa:10654; Q15126; Q5TZW9"	"Cholesterol biosynthesis pathway; Mevalonate pathway; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Cholesterol synthesis disorders; Cholesterol metabolism; Enterocyte cholesterol metabolism"	"Activation of gene expression by SREBF (SREBP); Cholesterol biosynthesis"	"8"	"0"	"159.0"	"111.2"	"167.0"	"159.5"	"159.7"	"216.9"	"329.0"	"1755.5"	"1836.3"	"4196.3"	"6361.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13310"	"Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1"	"0.000"	""	"11"	"5"	"10"	"1"	"644"	"70.7"	"9.26"	"1774.40"	"17.23"	"5"	"5"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf00658"	"8761"	"ENSG00000090621"	"PABPC4"	"B1ANQ8; hsa:8761; Q13310; Q4VC03; Q6P0N3"	""	""	"0"	"0"	"87.0"	"65.2"	"77.0"	"71.3"	"69.4"	"79.9"	"101.7"	"155.4"	"132.4"	"281.3"	"396.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P2E9"	"Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5"	"0.000"	""	"18"	"9"	"14"	"8"	"1410"	"152.4"	"8.60"	"3590.46"	"17.23"	"9"	"5"	"protein metabolism;other metabolic processes;transport"	"other membranes;ER/Golgi;translational apparatus"	"other molecular function"	"Pf05104"	"6238"	"ENSG00000125844"	"RRBP1"	"A0A0A0MRV0; A2A2S6; A6NCN6; hsa:6238; O75300; O75301; Q5W165; Q96SB2; Q9BWP1; Q9H476; Q9P2E9"	"Ectoderm differentiation"	"Signaling by ALK fusions and activated point mutants"	"2"	"0"	"796.9"	"730.7"	"798.1"	"752.1"	"797.8"	"742.2"	"1015.7"	"1420.9"	"1330.1"	"2143.8"	"2729.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15084"	"Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1"	"0.000"	""	"15"	"5"	"10"	"5"	"440"	"48.1"	"5.08"	"2060.47"	"17.20"	"5"	"5"	"protein metabolism;other metabolic processes;stress response"	"non-structural extracellular;plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00085"	"10130"	"ENSG00000143870"	"PDIA6"	"B3KY95; B5MCQ5; B7Z254; B7Z4M8; F8WA83; hsa:10130; Q15084; Q53RC7; Q6ZSH5; Q99778"	"Photodynamic therapy-induced unfolded protein response; VEGFA-VEGFR2 signaling"	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; XBP1(S) activates chaperone genes"	"5"	"0"	"595.3"	"428.0"	"607.5"	"542.8"	"543.8"	"604.8"	"713.1"	"956.6"	"940.6"	"1412.4"	"1714.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P54578"	"Ubiquitin carboxyl-terminal hydrolase 14 OS=Homo sapiens OX=9606 GN=USP14 PE=1 SV=3"	"0.000"	""	"14"	"4"	"5"	"4"	"494"	"56.0"	"5.30"	"377.71"	"17.19"	"1"	"4"	"cell-cell signaling;protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00443"	"9097"	"ENSG00000101557"	"USP14"	"B7Z4N8; hsa:9097; J3QRZ5; P54578; Q53XY5"	""	"Ub-specific processing proteases; Regulation of NF-kappa B signaling"	"2"	"0"	"76.3"	"50.5"	"66.6"	"71.6"	"59.5"	"58.0"	"84.8"	"154.1"	"133.8"	"543.0"	"1751.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62829"	"60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1"	"0.000"	""	"47"	"5"	"9"	"5"	"140"	"14.9"	"10.51"	"1444.69"	"17.17"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00238"	"9349"	"ENSG00000125691"	"RPL23"	"hsa:9349; P23131; P24048; P62829; Q29246; Q3SWV7; Q6P5S1"	"Cytoplasmic ribosomal proteins; 17q12 copy number variation syndrome"	"Regulation of expression of SLITs and ROBOs; SRP-dependent cotranslational protein targeting to membrane; Response of EIF2AK4 (GCN2) to amino acid deficiency; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"15"	"0"	"459.3"	"394.2"	"422.5"	"402.2"	"392.5"	"385.4"	"548.1"	"908.6"	"820.5"	"1859.1"	"2745.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49757"	"Protein numb homolog OS=Homo sapiens OX=9606 GN=NUMB PE=1 SV=2"	"0.000"	""	"8"	"4"	"8"	"4"	"651"	"70.8"	"8.51"	"1261.89"	"17.14"	"2"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00640, Pf06311"	"8650"	"ENSG00000133961"	"NUMB"	"B1P2N5; B1P2N6; B1P2N7; B1P2N8; B1P2N9; B4E2B1; hsa:8650; P49757; Q6NUQ7; Q86SY1; Q8WW73; Q9UBG1; Q9UEQ4; Q9UKE8; Q9UKE9; Q9UKF0; Q9UQJ4"	"Notch signaling; VEGFA-VEGFR2 signaling; Head and neck squamous cell carcinoma; Neurogenesis regulation in the olfactory epithelium; TROP2 regulatory signaling; Notch signaling pathway"	"Recycling pathway of L1; Degradation of GLI1 by the proteasome; Hedgehog 'on' state; Activated NOTCH1 Transmits Signal to the Nucleus"	"10"	"0"	"122.9"	"106.3"	"130.8"	"111.3"	"121.7"	"142.9"	"224.2"	"601.0"	"577.3"	"1005.1"	"1007.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H410"	"Kinetochore-associated protein DSN1 homolog OS=Homo sapiens OX=9606 GN=DSN1 PE=1 SV=2"	"0.000"	""	"14"	"4"	"8"	"4"	"356"	"40.0"	"7.05"	"1555.62"	"17.14"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cytoplasmic organelle;other cell component"	""	"Pf08202"	"79980"	"ENSG00000149636"	"DSN1"	"B4DWT2; E1P5U9; hsa:79980; Q5JW55; Q5JW56; Q9H410; Q9H8P4"	""	"Neutrophil degranulation; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"7"	"0"	"109.2"	"81.5"	"130.2"	"106.7"	"106.9"	"104.8"	"146.3"	"480.1"	"517.5"	"1312.2"	"1731.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q09161"	"Nuclear cap-binding protein subunit 1 OS=Homo sapiens OX=9606 GN=NCBP1 PE=1 SV=1"	"0.000"	""	"9"	"6"	"11"	"6"	"790"	"91.8"	"6.43"	"2240.67"	"17.12"	"5"	"5"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02854, Pf09088, Pf09090"	"4686"	"ENSG00000136937"	"NCBP1"	"B2R718; hsa:4686; Q09161; Q59G76; Q5T1V0; Q5T7X2"	"mRNA processing; 3q29 copy number variation syndrome"	"mRNA Splicing - Major Pathway; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; snRNP Assembly; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Abortive elongation of HIV-1 transcript in the absence of Tat; RNA Polymerase II Pre-transcription Events; RNA polymerase II transcribes snRNA genes; mRNA Capping; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Signaling by FGFR2 IIIa TM; Processing of Intronless Pre-mRNAs; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"29"	"0"	"291.9"	"216.6"	"289.0"	"277.5"	"258.3"	"259.7"	"377.0"	"641.7"	"641.8"	"1689.1"	"2619.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y697"	"Cysteine desulfurase, mitochondrial OS=Homo sapiens OX=9606 GN=NFS1 PE=1 SV=3"	"0.000"	""	"13"	"4"	"8"	"4"	"457"	"50.2"	"8.31"	"1790.07"	"17.05"	"4"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf00266"	"9054"	"ENSG00000244005"	"NFS1"	"B3KMA5; B4DXK9; E1P5R8; F5GYK5; hsa:9054; Q6P0L8; Q9NTZ5; Q9Y481; Q9Y697"	"Iron-sulfur cluster biogenesis"	""	"1"	"0"	"131.1"	"115.0"	"126.7"	"118.2"	"117.6"	"121.3"	"170.2"	"382.5"	"369.9"	"974.5"	"1313.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVI7"	"ATPase family AAA domain-containing protein 3A OS=Homo sapiens OX=9606 GN=ATAD3A PE=1 SV=2"	"0.000"	""	"7"	"4"	"7"	"1"	"634"	"71.3"	"8.98"	"1092.01"	"17.04"	"3"	"4"	"cell organization and biogenesis;stress response;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf00004, Pf12037"	"55210"	"ENSG00000197785"	"ATAD3A"	"B3KPB3; D2K8Q1; G3V1I6; hsa:55210; Q5SV23; Q8N275; Q96A50; Q9NVI7"	"1p36 copy number variation syndrome"	""	"1"	"0"	"30.2"	"18.4"	"28.6"	"24.2"	"22.5"	"28.9"	"35.0"	"52.5"	"55.0"	"141.6"	"209.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60885"	"Bromodomain-containing protein 4 OS=Homo sapiens OX=9606 GN=BRD4 PE=1 SV=2"	"0.000"	""	"4"	"5"	"10"	"4"	"1362"	"152.1"	"9.19"	"1885.90"	"17.02"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00439, Pf17035, Pf17105"	"23476"	"ENSG00000141867"	"BRD4"	"hsa:23476; O60433; O60885; Q4G0X8; Q86YS8; Q96PD3"	"VEGFA-VEGFR2 signaling; 7q11.23 copy number variation syndrome"	"Potential therapeutics for SARS"	"3"	"1"	"530.7"	"415.0"	"532.3"	"499.3"	"497.6"	"489.4"	"617.7"	"1048.5"	"1013.9"	"2025.7"	"2597.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95400"	"CD2 antigen cytoplasmic tail-binding protein 2 OS=Homo sapiens OX=9606 GN=CD2BP2 PE=1 SV=1"	"0.000"	""	"22"	"6"	"11"	"6"	"341"	"37.6"	"4.61"	"3183.41"	"17.02"	"6"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf02213"	"10421"	"ENSG00000169217"	"CD2BP2"	"B2RDX2; hsa:10421; O95400; Q9ULP2"	"mRNA processing; Ciliary landscape"	""	"2"	"0"	"443.1"	"358.7"	"416.4"	"371.2"	"347.0"	"370.6"	"525.4"	"1034.6"	"964.9"	"3598.6"	"6670.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3B9"	"RRP15-like protein OS=Homo sapiens OX=9606 GN=RRP15 PE=1 SV=2"	"0.000"	""	"15"	"3"	"6"	"3"	"282"	"31.5"	"5.52"	"693.42"	"17.01"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"other cell component"	""	"Pf07890"	"51018"	"ENSG00000067533"	"RRP15"	"hsa:51018; Q9Y3B9"	""	""	"0"	"0"	"213.3"	"176.6"	"240.8"	"225.3"	"227.6"	"235.3"	"298.5"	"430.4"	"384.8"	"668.4"	"837.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95785"	"Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2"	"0.000"	""	"3"	"3"	"5"	"3"	"1651"	"178.6"	"6.86"	"873.80"	"16.90"	"2"	"3"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	""	"58525"	"ENSG00000011451"	"WIZ"	"B3KVH1; B7ZM82; hsa:58525; M0QY21; O95785; Q4G0E0; Q6P6B0; Q6ZN24; Q7LDY6; Q7LDZ1; Q96IG5; Q96SQ6; Q9BUR8; Q9NPT1"	""	""	"0"	"0"	"123.1"	"83.6"	"131.0"	"127.6"	"121.4"	"96.7"	"146.5"	"243.4"	"223.0"	"435.4"	"510.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35612"	"Beta-adducin OS=Homo sapiens OX=9606 GN=ADD2 PE=1 SV=3"	"0.000"	""	"11"	"7"	"11"	"5"	"726"	"80.8"	"5.92"	"1773.48"	"16.90"	"5"	"6"	"cell adhesion;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00596"	"119"	"ENSG00000075340"	"ADD2"	"A8K4P2; B4DM17; D6W5G7; D6W5G8; hsa:119; P35612; Q13482; Q16412; Q59G82; Q5U5P4; Q6P0P2; Q6PGQ4; Q7Z688; Q7Z689; Q7Z690; Q7Z691"	""	"Miscellaneous transport and binding events"	"1"	"0"	"194.9"	"150.6"	"181.0"	"190.8"	"166.5"	"172.8"	"228.7"	"640.8"	"666.0"	"1392.2"	"1692.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14008"	"Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3"	"0.000"	""	"2"	"5"	"8"	"5"	"2032"	"225.4"	"7.80"	"1644.87"	"16.88"	"3"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02985, Pf12348"	"9793"	"ENSG00000175216"	"CKAP5"	"hsa:9793; Q05D70; Q0VAX7; Q0VAX8; Q14008; Q14668; Q2TA89; Q6NSH4"	"4p16.3 copy number variation"	"Separation of Sister Chromatids; Regulation of PLK1 Activity at G2/M Transition; RHO GTPases Activate Formins; Resolution of Sister Chromatid Cohesion; Recruitment of NuMA to mitotic centrosomes; EML4 and NUDC in mitotic spindle formation; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"14"	"0"	"367.2"	"338.4"	"369.7"	"340.0"	"374.3"	"379.5"	"484.1"	"658.2"	"645.0"	"1282.1"	"1711.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L576"	"Cytoplasmic FMR1-interacting protein 1 OS=Homo sapiens OX=9606 GN=CYFIP1 PE=1 SV=1"	"0.000"	""	"5"	"5"	"10"	"1"	"1253"	"145.1"	"6.90"	"1862.73"	"16.76"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf05994, Pf07159"	"23191"	"ENSG00000273749; ENSG00000288461"	"CYFIP1"	"A8K6D9; hsa:23191; Q14467; Q5IED0; Q6ZSX1; Q7L576; Q9BSD9; Q9BVC7"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; Prader-Willi and Angelman syndrome; Fragile X syndrome; Disruption of postsynaptic signaling by CNV; 15q11.2 copy number variation syndrome; G13 signaling pathway"	"VEGFA-VEGFR2 Pathway; Neutrophil degranulation; RAC3 GTPase cycle; RAC1 GTPase cycle; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHOG GTPase cycle; RHO GTPases Activate WASPs and WAVEs; RAC2 GTPase cycle"	"15"	"0"	"62.4"	"48.2"	"45.8"	"47.0"	"47.1"	"48.1"	"62.9"	"128.1"	"128.5"	"204.8"	"264.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62249"	"40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2"	"0.000"	""	"28"	"4"	"12"	"4"	"146"	"16.4"	"10.21"	"2204.56"	"16.76"	"4"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00380"	"6217"	"ENSG00000105193"	"RPS16"	"B2RDD5; hsa:6217; P17008; P62249"	"Cytoplasmic ribosomal proteins"	"SRP-dependent cotranslational protein targeting to membrane; SARS-CoV-1 modulates host translation machinery; Major pathway of rRNA processing in the nucleolus and cytosol; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"19"	"0"	"503.5"	"516.4"	"534.8"	"493.0"	"489.7"	"544.6"	"712.4"	"850.5"	"898.4"	"1635.3"	"2162.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13616"	"Cullin-1 OS=Homo sapiens OX=9606 GN=CUL1 PE=1 SV=2"	"0.000"	""	"11"	"7"	"11"	"7"	"776"	"89.6"	"8.00"	"1871.97"	"16.73"	"5"	"5"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00888, Pf10557"	"8454"	"ENSG00000055130"	"CUL1"	"D3DWG3; hsa:8454; O60719; Q08AL6; Q13616; Q8IYW1"	"Cell cycle; TNF-alpha signaling pathway; Parkin-ubiquitin proteasomal system pathway; Apoptosis-related network due to altered Notch3 in ovarian cancer; Glucocorticoid receptor pathway; Nuclear receptors meta-pathway; Pleural mesothelioma; Notch signaling pathway"	"Circadian Clock; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; SCF-beta-TrCP mediated degradation of Emi1; Degradation of beta-catenin by the destruction complex; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; NIK-->noncanonical NF-kB signaling; Orc1 removal from chromatin; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Neddylation; SCF(Skp2)-mediated degradation of p27/p21; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Regulation of PLK1 Activity at G2/M Transition; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Cyclin D associated events in G1; Regulation of BACH1 activity; MAP3K8 (TPL2)-dependent MAPK1/3 activation; NOTCH1 Intracellular Domain Regulates Transcription; Prolactin receptor signaling; Iron uptake and transport; Nuclear events stimulated by ALK signaling in cancer; Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling"	"40"	"0"	"357.5"	"253.7"	"404.2"	"356.5"	"322.3"	"333.8"	"445.3"	"1454.3"	"1603.1"	"3953.6"	"5055.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6IBS0"	"Twinfilin-2 OS=Homo sapiens OX=9606 GN=TWF2 PE=1 SV=2"	"0.000"	""	"19"	"4"	"6"	"3"	"349"	"39.5"	"6.84"	"1194.83"	"16.73"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00241"	"11344"	"ENSG00000247596"	"TWF2"	"hsa:11344; Q6IBS0; Q9Y3F5"	""	"Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea"	"2"	"1"	"126.5"	"81.9"	"176.1"	"122.9"	"118.0"	"121.2"	"168.3"	"471.9"	"507.0"	"1447.4"	"1653.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P26599"	"Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1"	"0.000"	""	"14"	"6"	"12"	"5"	"531"	"57.2"	"9.17"	"2780.87"	"16.69"	"5"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf11835, Pf13893"	"749887"	"ENSPPYG00000009289; ENSPTRG00000010165"	"PTBP1"	"A0A2J8IKP3; A0A2J8RA51; A0A6D2WFY9; A0A8I5YPF9; K7AXA8"	""	""	"0"	"2"	"990.3"	"797.2"	"1093.2"	"941.2"	"945.3"	"935.8"	"1277.0"	"1776.2"	"1652.6"	"3593.9"	"5060.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15061"	"WD repeat-containing protein 43 OS=Homo sapiens OX=9606 GN=WDR43 PE=1 SV=3"	"0.000"	""	"11"	"5"	"8"	"5"	"677"	"74.8"	"5.57"	"1977.17"	"16.67"	"3"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00400, Pf04003"	"23160"	"ENSG00000163811"	"WDR43"	"hsa:23160; Q15061; Q15395; Q92577"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"454.8"	"387.5"	"453.7"	"427.8"	"418.2"	"417.9"	"562.4"	"1108.1"	"1057.7"	"1764.2"	"2030.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N8S7"	"Protein enabled homolog OS=Homo sapiens OX=9606 GN=ENAH PE=1 SV=2"	"0.000"	""	"12"	"4"	"8"	"4"	"591"	"66.5"	"6.93"	"1834.33"	"16.65"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00568, Pf08776"	"55740"	"ENSG00000154380"	"ENAH"	"D0PQI2; hsa:55740; Q502W5; Q5T5M7; Q5VTQ9; Q5VTR0; Q8N8S7; Q9NVF3; Q9UFB8"	"Regulation of actin cytoskeleton"	"Generation of second messenger molecules; Signaling by ROBO receptors"	"3"	"0"	"277.9"	"203.6"	"274.9"	"260.8"	"254.3"	"257.2"	"291.8"	"364.8"	"366.4"	"650.1"	"899.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6SPF0"	"Atherin OS=Homo sapiens OX=9606 GN=SAMD1 PE=1 SV=1"	"0.000"	""	"6"	"3"	"7"	"3"	"538"	"56.0"	"7.58"	"964.95"	"16.64"	"2"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"other molecular function"	"Pf00536"	"90378"	"ENSG00000288488"	"SAMD1"	"hsa:90378; Q6P0R3; Q6PIS7; Q6SPF0; Q96IM4"	""	""	"0"	"0"	"202.9"	"165.3"	"173.3"	"169.1"	"183.6"	"191.5"	"211.2"	"295.5"	"282.6"	"482.4"	"648.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13595"	"Transformer-2 protein homolog alpha OS=Homo sapiens OX=9606 GN=TRA2A PE=1 SV=1"	"0.000"	""	"17"	"5"	"12"	"5"	"282"	"32.7"	"11.27"	"1808.43"	"16.63"	"4"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf00076"	"29896"	"ENSG00000164548"	"TRA2A"	"B4DQI6; B4DUA9; E9PD75; hsa:29896; Q13595"	"Orexin receptor pathway"	""	"1"	"0"	"512.5"	"470.9"	"435.5"	"387.3"	"400.0"	"380.5"	"552.0"	"856.7"	"728.3"	"1442.6"	"2257.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96JM3"	"Chromosome alignment-maintaining phosphoprotein 1 OS=Homo sapiens OX=9606 GN=CHAMP1 PE=1 SV=2"	"0.000"	""	"9"	"6"	"10"	"6"	"812"	"89.0"	"8.44"	"2049.63"	"16.61"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	""	"283489"	"ENSG00000198824"	"CHAMP1"	"B3KU06; hsa:283489; Q6P181; Q8NC88; Q96JM3; Q9BST0"	""	""	"0"	"0"	"446.6"	"336.2"	"392.7"	"390.6"	"347.6"	"378.3"	"436.7"	"675.4"	"675.4"	"1172.2"	"1187.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TDN6"	"Ribosome biogenesis protein BRX1 homolog OS=Homo sapiens OX=9606 GN=BRIX1 PE=1 SV=2"	"0.000"	""	"13"	"4"	"10"	"4"	"353"	"41.4"	"9.92"	"1794.55"	"16.60"	"4"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf04427"	"55299"	"ENSG00000113460"	"BRIX1"	"A8K0P5; hsa:55299; Q3ZTT4; Q8N453; Q8TDN6; Q96DH1"	"Gastric cancer network 2"	""	"1"	"0"	"126.8"	"92.0"	"221.9"	"152.5"	"171.7"	"168.2"	"185.1"	"305.2"	"296.7"	"697.0"	"1020.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96NC0"	"Zinc finger matrin-type protein 2 OS=Homo sapiens OX=9606 GN=ZMAT2 PE=1 SV=1"	"0.000"	""	"27"	"7"	"14"	"7"	"199"	"23.6"	"9.01"	"2337.54"	"16.59"	"7"	"5"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf12171"	"153527"	"ENSG00000146007"	"ZMAT2"	"hsa:153527; Q96NC0"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"1920.0"	"1368.9"	"1748.6"	"1698.1"	"1588.3"	"1556.8"	"2078.4"	"3163.9"	"2809.3"	"4306.1"	"4900.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HAU0"	"Pleckstrin homology domain-containing family A member 5 OS=Homo sapiens OX=9606 GN=PLEKHA5 PE=1 SV=1"	"0.000"	""	"5"	"5"	"10"	"5"	"1116"	"127.4"	"7.53"	"1864.23"	"16.56"	"5"	"5"	"developmental processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00169, Pf00397"	"54477"	"ENSG00000052126"	"PLEKHA5"	"A0JP03; B4DGS1; E9PHQ3; F5H0I0; hsa:54477; Q6NSF8; Q86ST7; Q8N3K6; Q96DY9; Q9BVR4; Q9C0H7; Q9H924; Q9HAU0; Q9NVK8"	""	"Synthesis of PIPs at the plasma membrane"	"1"	"0"	"447.0"	"393.4"	"417.9"	"422.4"	"402.9"	"418.5"	"478.6"	"729.2"	"673.5"	"1177.9"	"1343.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P33176"	"Kinesin-1 heavy chain OS=Homo sapiens OX=9606 GN=KIF5B PE=1 SV=1"	"0.000"	""	"6"	"5"	"9"	"5"	"963"	"109.6"	"6.51"	"1334.01"	"16.55"	"4"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225"	"3799"	"ENSG00000170759"	"KIF5B"	"A0AVB2; hsa:3799; P33176; Q5VZ85"	"Alzheimer's disease and miRNA effects; Envelope proteins and their potential roles in EDMD physiopathology; Insulin signaling; CCL18 signaling pathway; Alzheimer's disease"	"COPI-dependent Golgi-to-ER retrograde traffic; MHC class II antigen presentation; Kinesins; Insulin processing; Nuclear events stimulated by ALK signaling in cancer; RHO GTPases activate KTN1"	"12"	"0"	"137.1"	"87.5"	"177.1"	"139.2"	"152.5"	"166.2"	"201.4"	"495.2"	"522.2"	"1564.8"	"1918.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P20248"	"Cyclin-A2 OS=Homo sapiens OX=9606 GN=CCNA2 PE=1 SV=2"	"0.000"	""	"12"	"3"	"5"	"3"	"432"	"48.5"	"6.54"	"1033.90"	"16.55"	"2"	"3"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00134, Pf02984, Pf16500"	"890"	"ENSG00000145386"	"CCNA2"	"A8K7B6; hsa:890; P20248; Q2M3U6; Q4W5P4; Q6LER8"	"AMP-activated protein kinase signaling; Cell cycle; Retinoblastoma gene in cancer; IL-18 signaling pathway"	"TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; Regulation of TP53 Degradation; SCF(Skp2)-mediated degradation of p27/p21; Regulation of TP53 Activity through Phosphorylation; G2 Phase; Telomere Extension By Telomerase; Regulation of APC/C activators between G1/S and early anaphase; Senescence-Associated Secretory Phenotype (SASP); Processing of DNA double-strand break ends; DNA Damage/Telomere Stress Induced Senescence; p53-Dependent G1 DNA Damage Response; Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1; Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes"	"24"	"0"	"188.2"	"138.7"	"155.2"	"145.8"	"119.2"	"207.1"	"184.4"	"417.3"	"416.0"	"988.2"	"1358.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96F07"	"Cytoplasmic FMR1-interacting protein 2 OS=Homo sapiens OX=9606 GN=CYFIP2 PE=1 SV=2"	"0.000"	""	"5"	"5"	"10"	"1"	"1278"	"148.3"	"7.31"	"1856.74"	"16.42"	"5"	"5"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf05994, Pf07159"	"26999"	"ENSG00000055163"	"CYFIP2"	"A6NLT2; D3DQJ3; hsa:26999; Q53EN5; Q96F07; Q9NTK4; Q9ULQ2; Q9UN29"	"Fragile X syndrome; Regulation of actin cytoskeleton"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RAC1 GTPase cycle; RHO GTPases Activate WASPs and WAVEs; VEGFA-VEGFR2 Pathway"	"7"	"4"	"292.5"	"173.2"	"269.2"	"275.0"	"273.3"	"251.2"	"370.4"	"907.0"	"971.8"	"1718.3"	"2197.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92905"	"COP9 signalosome complex subunit 5 OS=Homo sapiens OX=9606 GN=COPS5 PE=1 SV=4"	"0.000"	""	"21"	"6"	"9"	"6"	"334"	"37.6"	"6.54"	"1263.76"	"16.38"	"4"	"5"	"protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01398, Pf18323"	"10987"	"ENSG00000121022"	"COPS5"	"hsa:10987; O15386; Q6AW95; Q86WQ4; Q92905; Q9BQ17"	""	"Cargo recognition for clathrin-mediated endocytosis; Neddylation; Formation of TC-NER Pre-Incision Complex; DNA Damage Recognition in GG-NER"	"4"	"0"	"48.1"	"29.2"	"51.4"	"44.5"	"51.4"	"59.2"	"80.4"	"342.2"	"350.7"	"1634.4"	"3431.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60749"	"Sorting nexin-2 OS=Homo sapiens OX=9606 GN=SNX2 PE=1 SV=2"	"0.000"	""	"10"	"5"	"9"	"4"	"519"	"58.4"	"5.12"	"1520.39"	"16.34"	"4"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00787, Pf03700, Pf09325"	"6643"	"ENSG00000205302"	"SNX2"	"B3KN44; B4DEK4; B7Z408; hsa:6643; O43650; O60749; P82862; Q53XK8; Q597H6; Q9BTS8"	""	"Golgi Associated Vesicle Biogenesis"	"1"	"1"	"98.2"	"84.7"	"117.6"	"106.6"	"106.2"	"108.3"	"128.8"	"262.4"	"271.8"	"1099.5"	"2072.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NBJ5"	"Procollagen galactosyltransferase 1 OS=Homo sapiens OX=9606 GN=COLGALT1 PE=1 SV=1"	"0.000"	""	"9"	"5"	"11"	"5"	"622"	"71.6"	"7.31"	"2008.35"	"16.25"	"5"	"4"	"cell organization and biogenesis;other biological processes"	"ER/Golgi"	"other molecular function"	"Pf01755, Pf13704"	"79709"	"ENSG00000130309"	"COLGALT1"	"hsa:79709; Q8NBJ5; Q8NC64"	"Type I collagen synthesis in the context of osteogenesis imperfecta"	"Collagen biosynthesis and modifying enzymes"	"2"	"0"	"333.5"	"247.3"	"334.2"	"319.5"	"306.7"	"295.5"	"434.1"	"986.0"	"937.8"	"2497.6"	"3664.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NWH9"	"SAFB-like transcription modulator OS=Homo sapiens OX=9606 GN=SLTM PE=1 SV=2"	"0.000"	""	"5"	"5"	"10"	"5"	"1034"	"117.1"	"7.87"	"1794.41"	"16.23"	"5"	"5"	"other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf02037"	"79811"	"ENSG00000137776"	"SLTM"	"A8K5V8; B2RTX3; hsa:79811; Q2VPK7; Q52MB3; Q658J7; Q6ZNF2; Q86TK6; Q9H7C3; Q9H8U9; Q9NWH9"	""	""	"0"	"0"	"463.4"	"410.5"	"478.5"	"456.9"	"438.8"	"435.9"	"563.3"	"747.1"	"749.4"	"1460.0"	"2181.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P18124"	"60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1"	"0.000"	""	"19"	"4"	"9"	"4"	"248"	"29.2"	"10.65"	"1682.86"	"16.23"	"3"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00327, Pf08079"	"6129"	"ENSG00000147604"	"RPL7"	"A8K504; hsa:6129; P18124; Q15289; Q3KQU0; Q5I0X1; Q6IBM9"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"15"	"0"	"474.5"	"308.1"	"531.8"	"441.5"	"417.0"	"474.6"	"612.7"	"815.0"	"743.9"	"1625.9"	"2344.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14745"	"Na(+)/H(+) exchange regulatory cofactor NHE-RF1 OS=Homo sapiens OX=9606 GN=SLC9A3R1 PE=1 SV=4"	"0.000"	""	"14"	"5"	"10"	"5"	"358"	"38.8"	"5.77"	"1700.08"	"16.17"	"5"	"5"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;transporter activity;cytoskeletal activity;other molecular function"	"Pf00595, Pf09007"	"9368"	"ENSG00000109062"	"NHERF1"	"B3KY21; hsa:9368; O14745; O43552; Q86WQ5"	"TAR syndrome"	""	"1"	"0"	"109.6"	"77.7"	"142.9"	"121.3"	"110.7"	"111.7"	"136.5"	"361.5"	"406.8"	"1290.8"	"1885.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52789"	"Hexokinase-2 OS=Homo sapiens OX=9606 GN=HK2 PE=1 SV=2"	"0.000"	""	"7"	"6"	"11"	"5"	"917"	"102.3"	"6.05"	"1814.03"	"16.08"	"6"	"5"	"cell organization and biogenesis;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;other cell component"	"kinase activity;other molecular function"	"Pf00349, Pf03727"	"3099"	"ENSG00000159399"	"HK2"	"D6W5J2; hsa:3099; P52789; Q8WU87; Q9UN82"	"Clear cell renal cell carcinoma pathways; Warburg effect modulated by deubiquitinating enzymes and their substrates; Glycolysis and gluconeogenesis; A network map of Macrophage-stimulating protein (MSP) signaling; Metabolic Epileptic Disorders; UDP-derived sugars synthesis in fibroblasts"	"Glycolysis"	"7"	"1"	"176.2"	"133.5"	"171.4"	"149.3"	"154.1"	"176.0"	"217.6"	"777.5"	"875.4"	"2360.3"	"3620.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15226"	"NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2"	"0.000"	""	"10"	"5"	"8"	"5"	"690"	"77.6"	"8.79"	"1794.49"	"16.05"	"4"	"4"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01424, Pf01585"	"55922"	"ENSG00000186416"	"NKRF"	"G3V1N1; hsa:55922; O15226; Q4VC41; Q9UJ91"	"Pathogenesis of SARS-CoV-2 mediated by nsp9-nsp10 complex; Network map of SARS-CoV-2 signaling pathway"	""	"2"	"0"	"462.6"	"400.8"	"375.8"	"376.1"	"379.1"	"414.3"	"535.2"	"656.5"	"640.3"	"1001.5"	"1470.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P12235"	"ADP/ATP translocase 1 OS=Homo sapiens OX=9606 GN=SLC25A4 PE=1 SV=4"	"0.000"	""	"18"	"5"	"10"	"1"	"298"	"33.0"	"9.76"	"1738.64"	"16.04"	"4"	"5"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;mitochondrion"	"transporter activity"	"Pf00153"	"291"	"ENSG00000151729"	"SLC25A4"	"D3DP59; hsa:291; P12235"	"Electron transport chain: OXPHOS system in mitochondria; Alzheimer's disease and miRNA effects; Synaptic vesicle pathway; Alzheimer's disease; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane; Mitochondrial protein import; Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization"	"8"	"0"	"22.6"	"23.3"	"31.7"	"23.2"	"28.1"	"34.1"	"31.2"	"54.0"	"58.8"	"117.3"	"165.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49590"	"Histidine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=HARS2 PE=1 SV=1"	"0.000"	""	"12"	"6"	"12"	"1"	"506"	"56.9"	"8.24"	"1987.64"	"16.03"	"6"	"6"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf03129, Pf13393"	"23438"	"ENSG00000112855"	"HARS2"	"B4DDY8; hsa:23438; P49590"	"Primary ovarian insufficiency"	"Mitochondrial tRNA aminoacylation"	"2"	"0"	"8.0"	"5.9"	"7.9"	"11.7"	"10.7"	"7.1"	"9.1"	"22.0"	"22.9"	"49.3"	"57.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43148"	"mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1"	"0.000"	""	"11"	"5"	"10"	"5"	"476"	"54.8"	"6.61"	"1879.79"	"16.01"	"5"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03291"	"8731"	"ENSG00000101654"	"RNMT"	"B0YJ90; D3DUJ5; hsa:8731; O43148; O94996; Q9UIJ9"	"mRNA processing; 15q25 copy number variation"	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE"	"5"	"0"	"303.9"	"246.1"	"298.5"	"274.2"	"267.1"	"281.9"	"356.7"	"653.9"	"630.6"	"1310.7"	"1760.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UIG0"	"Tyrosine-protein kinase BAZ1B OS=Homo sapiens OX=9606 GN=BAZ1B PE=1 SV=2"	"0.000"	""	"4"	"5"	"11"	"5"	"1483"	"170.8"	"8.48"	"2205.53"	"16.00"	"5"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00439, Pf00628, Pf10537, Pf15612, Pf15613"	"9031"	"ENSG00000009954"	"BAZ1B"	"B9EGK3; D3DXE9; hsa:9031; O95039; O95247; O95277; Q6P1K4; Q86UJ6; Q9UIG0"	"IL-18 signaling pathway; 7q11.23 copy number variation syndrome; 10q11.21q11.23 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"	"5"	"0"	"468.5"	"364.8"	"456.2"	"408.7"	"420.8"	"415.2"	"538.2"	"1033.8"	"1007.3"	"1796.7"	"2134.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BQ52"	"Zinc phosphodiesterase ELAC protein 2 OS=Homo sapiens OX=9606 GN=ELAC2 PE=1 SV=2"	"0.000"	""	"5"	"3"	"6"	"3"	"826"	"92.2"	"7.90"	"693.84"	"15.98"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf12706, Pf13691"	"60528"	"ENSG00000006744"	"ELAC2"	"B4DPL9; hsa:60528; Q6IA94; Q9BQ52; Q9HAS8; Q9HAS9; Q9NVT1"	""	"tRNA processing in the nucleus; tRNA processing in the mitochondrion; rRNA processing in the mitochondrion; tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis"	"4"	"0"	"28.8"	"12.4"	"36.7"	"29.5"	"27.5"	"25.4"	"48.8"	"98.5"	"90.9"	"287.4"	"447.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16555"	"Dihydropyrimidinase-related protein 2 OS=Homo sapiens OX=9606 GN=DPYSL2 PE=1 SV=1"	"0.000"	""	"7"	"3"	"7"	"3"	"572"	"62.3"	"6.38"	"1175.50"	"15.95"	"2"	"3"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton"	"other molecular function"	"Pf01979"	"1808"	"ENSG00000092964"	"DPYSL2"	"A8K5H2; B4DR31; D3DSS7; hsa:1808; O00424; Q16555"	"Microtubule cytoskeleton regulation; Brain-derived neurotrophic factor (BDNF) signaling pathway"	"Recycling pathway of L1; CRMPs in Sema3A signaling"	"4"	"0"	"38.8"	"30.4"	"36.4"	"28.6"	"34.3"	"37.3"	"55.5"	"89.7"	"84.5"	"262.1"	"531.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P67870"	"Casein kinase II subunit beta OS=Homo sapiens OX=9606 GN=CSNK2B PE=1 SV=1"	"0.000"	""	"20"	"4"	"8"	"4"	"215"	"24.9"	"5.55"	"1400.04"	"15.87"	"4"	"4"	"cell-cell signaling;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;kinase activity;other molecular function"	"Pf01214"	"1460"	"ENSG00000204435; ENSG00000206406; ENSG00000224398; ENSG00000224774; ENSG00000228875; ENSG00000230700; ENSG00000232960"	"CSNK2B"	"B0UXA9; hsa:1460; P07312; P13862; P67870; Q4VX47"	"Alzheimer's disease and miRNA effects; lncRNA in canonical Wnt signaling and colorectal cancer; Breast cancer pathway; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Measles virus infection; Pleural mesothelioma; Alzheimer's disease"	"Neutrophil degranulation; Condensation of Prometaphase Chromosomes; Regulation of PTEN stability and activity; KEAP1-NFE2L2 pathway; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Regulation of TP53 Activity through Phosphorylation; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; WNT mediated activation of DVL; Signal transduction by L1; Receptor Mediated Mitophagy; Synthesis of PC"	"19"	"0"	"432.7"	"305.9"	"336.0"	"344.9"	"334.4"	"305.1"	"474.0"	"694.1"	"572.2"	"1914.2"	"4027.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WU90"	"Zinc finger CCCH domain-containing protein 15 OS=Homo sapiens OX=9606 GN=ZC3H15 PE=1 SV=1"	"0.000"	""	"13"	"5"	"10"	"5"	"426"	"48.6"	"5.31"	"2310.68"	"15.85"	"5"	"4"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00642, Pf16543"	"55854"	"ENSG00000065548"	"ZC3H15"	"B4DMW2; D3DPG7; hsa:55854; Q5QTQ4; Q8WU90; Q8WZ06; Q9NUZ3; Q9NZ37; Q9P079"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"713.8"	"640.2"	"692.6"	"649.3"	"688.8"	"715.5"	"910.1"	"1147.6"	"1084.7"	"1995.0"	"1883.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TF01"	"Arginine/serine-rich protein PNISR OS=Homo sapiens OX=9606 GN=PNISR PE=1 SV=2"	"0.000"	""	"8"	"6"	"11"	"6"	"805"	"92.5"	"10.02"	"1901.91"	"15.84"	"6"	"5"	""	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	""	"Pf15996"	"25957"	"ENSG00000132424"	"PNISR"	"A8K540; E1P5D2; hsa:25957; Q5T064; Q5T065; Q6P2B4; Q6P2N4; Q6PJ93; Q6PK36; Q7Z640; Q8N2L1; Q8TF00; Q8TF01; Q96K10; Q96SI3; Q96SM5; Q9P076; Q9P0C0; Q9Y4N3"	""	""	"0"	"0"	"682.7"	"531.4"	"673.2"	"662.0"	"592.3"	"582.9"	"722.6"	"868.2"	"883.9"	"1206.5"	"1547.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H9A6"	"Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1"	"0.000"	""	"8"	"4"	"10"	"4"	"602"	"68.2"	"6.43"	"1765.68"	"15.82"	"4"	"4"	""	""	""	"Pf00560, Pf13855"	"55631"	"ENSG00000066557"	"LRRC40"	"hsa:55631; Q9BTR7; Q9H9A6; Q9NSK1; Q9NXC1"	""	""	"0"	"0"	"79.7"	"57.7"	"88.8"	"74.5"	"80.7"	"66.5"	"93.4"	"231.9"	"288.1"	"1215.6"	"1672.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13576"	"Ras GTPase-activating-like protein IQGAP2 OS=Homo sapiens OX=9606 GN=IQGAP2 PE=1 SV=4"	"0.000"	""	"4"	"5"	"8"	"3"	"1575"	"180.5"	"5.64"	"1258.56"	"15.81"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00307, Pf00612, Pf00616, Pf03836"	"10788"	"ENSG00000145703"	"IQGAP2"	"A8K4V1; B7Z8A4; hsa:10788; J3KR91; Q13576"	"Ciliary landscape; G13 signaling pathway"	"Neutrophil degranulation; RHO GTPases activate IQGAPs; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOG GTPase cycle"	"7"	"0"	"44.0"	"33.5"	"50.9"	"53.5"	"40.1"	"53.1"	"75.4"	"247.8"	"250.1"	"641.7"	"748.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14561"	"Acyl carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFAB1 PE=1 SV=3"	"0.000"	""	"19"	"4"	"8"	"4"	"156"	"17.4"	"4.93"	"1683.60"	"15.80"	"4"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"other membranes;cytosol;mitochondrion;nucleus"	"translation activity;other molecular function"	"Pf00550"	"4706"	"ENSG00000004779"	"NDUFAB1"	"B2R4M1; hsa:4706; O14561; Q9UNV1"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Glyoxylate metabolism and glycine degradation; Mitochondrial Fatty Acid Beta-Oxidation; Complex I biogenesis"	"7"	"0"	"217.6"	"179.9"	"217.7"	"191.1"	"195.3"	"217.2"	"322.9"	"890.2"	"813.5"	"2337.0"	"3469.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43447"	"Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1"	"0.000"	""	"28"	"5"	"10"	"5"	"177"	"19.2"	"8.07"	"1916.34"	"15.79"	"4"	"5"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00160"	"10465"	"ENSG00000171960"	"PPIH"	"A6NNE7; hsa:10465; O43447"	""	"mRNA Splicing - Major Pathway; SARS-CoV-1 activates/modulates innate immune responses"	"2"	"0"	"482.5"	"384.4"	"545.5"	"502.0"	"468.3"	"457.1"	"666.0"	"1025.2"	"943.6"	"1805.1"	"2703.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P27708"	"CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3"	"0.000"	""	"3"	"5"	"8"	"5"	"2225"	"242.8"	"6.46"	"1452.87"	"15.79"	"4"	"4"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00117, Pf00185, Pf00988, Pf01979, Pf02142, Pf02729, Pf02786, Pf02787"	"790"	"ENSG00000084774"	"CAD"	"D6W552; hsa:790; P27708; Q6P0Q0; Q96CK3"	"Endothelin pathways; Amino acid metabolism; Pyrimidine metabolism"	"Pyrimidine biosynthesis"	"4"	"0"	"173.9"	"122.7"	"162.9"	"161.0"	"155.3"	"148.5"	"190.3"	"348.3"	"372.2"	"1086.9"	"1695.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15022"	"Polycomb protein SUZ12 OS=Homo sapiens OX=9606 GN=SUZ12 PE=1 SV=3"	"0.000"	""	"7"	"3"	"5"	"3"	"739"	"83.0"	"8.81"	"963.22"	"15.71"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf09733"	"23512"	"ENSG00000178691"	"SUZ12"	"hsa:23512; Q15022; Q96BD9"	"Interactome of polycomb repressive complex 2 (PRC2) ; Tumor suppressor activity of SMARCB1; Epithelial to mesenchymal transition in colorectal cancer; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; Pleural mesothelioma"	"HCMV Early Events; Oxidative Stress Induced Senescence; Activation of anterior HOX genes in hindbrain development during early embryogenesis; PRC2 methylates histones and DNA; Defective pyroptosis; SUMOylation of chromatin organization proteins; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6; PKMTs methylate histone lysines"	"14"	"0"	"41.4"	"32.6"	"39.1"	"40.3"	"31.3"	"40.4"	"57.8"	"130.6"	"135.2"	"279.0"	"329.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92688"	"Acidic leucine-rich nuclear phosphoprotein 32 family member B OS=Homo sapiens OX=9606 GN=ANP32B PE=1 SV=1"	"0.000"	""	"22"	"5"	"10"	"3"	"251"	"28.8"	"4.06"	"1905.72"	"15.69"	"5"	"4"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf12799"	"10541"	"ENSG00000136938"	"ANP32B"	"B2R9C7; hsa:10541; O00655; P78458; P78459; Q92688"	""	""	"0"	"0"	"212.9"	"220.9"	"275.2"	"245.9"	"234.3"	"234.0"	"324.4"	"491.6"	"442.0"	"1070.1"	"1622.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15007"	"Pre-mRNA-splicing regulator WTAP OS=Homo sapiens OX=9606 GN=WTAP PE=1 SV=2"	"0.000"	""	"12"	"3"	"6"	"3"	"396"	"44.2"	"5.19"	"1452.65"	"15.69"	"3"	"3"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf17098"	"9589"	"ENSG00000146457"	"WTAP"	"hsa:9589; Q15007; Q5TCL8; Q5TCL9; Q96T28; Q9BYJ7; Q9H4E2"	""	"Processing of Capped Intron-Containing Pre-mRNA"	"1"	"0"	"89.8"	"53.8"	"100.5"	"80.6"	"81.9"	"93.0"	"114.5"	"261.6"	"271.4"	"863.8"	"1691.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q02818"	"Nucleobindin-1 OS=Homo sapiens OX=9606 GN=NUCB1 PE=1 SV=4"	"0.000"	""	"12"	"4"	"6"	"4"	"461"	"53.8"	"5.25"	"696.84"	"15.68"	"2"	"4"	"signal transduction"	"ER/Golgi"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf13499"	"4924"	"ENSG00000104805"	"NUCB1"	"B2RD64; hsa:4924; Q02818; Q15838; Q7Z4J7; Q9BUR1"	""	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation"	"2"	"0"	"418.3"	"333.9"	"379.8"	"396.4"	"345.3"	"342.7"	"441.1"	"591.1"	"584.3"	"1084.5"	"1595.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P06493"	"Cyclin-dependent kinase 1 OS=Homo sapiens OX=9606 GN=CDK1 PE=1 SV=3"	"0.000"	""	"15"	"4"	"8"	"3"	"297"	"34.1"	"8.40"	"1674.82"	"15.67"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069"	"983"	"ENSG00000170312"	"CDK1"	"A8K7C4; C9J497; hsa:983; O60764; P06493"	"miRNA regulation of DNA damage response; Cell cycle; Microtubule cytoskeleton regulation; Spinal cord injury; Retinoblastoma gene in cancer; ATM signaling pathway; PPAR-alpha pathway; Nuclear receptors meta-pathway; ATM signaling in development and disease ; G1 to S cell cycle control; Cohesin complex - Cornelia de Lange syndrome; Urotensin-II-mediated signaling pathway; DNA damage response"	"Golgi Cisternae Pericentriolar Stack Reorganization; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; MAPK6/MAPK4 signaling; The role of GTSE1 in G2/M progression after G2 checkpoint; Resolution of Sister Chromatid Cohesion; Recruitment of NuMA to mitotic centrosomes; Nuclear Pore Complex (NPC) Disassembly; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Regulation of TP53 Degradation; APC/C:Cdc20 mediated degradation of Cyclin B; Phosphorylation of the APC/C; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Transcriptional regulation by RUNX2; Ovarian tumor domain proteases; MASTL Facilitates Mitotic Progression; E2F-enabled inhibition of pre-replication complex formation; MAPK3 (ERK1) activation; Condensation of Prophase Chromosomes; G1/S-Specific Transcription; Initiation of Nuclear Envelope (NE) Reformation; Condensation of Prometaphase Chromosomes; Activation of NIMA Kinases NEK9, NEK6, NEK7; G2/M DNA replication checkpoint; Depolymerization of the Nuclear Lamina; Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1; Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes; Phosphorylation of Emi1"	"49"	"1"	"223.8"	"164.3"	"236.0"	"194.7"	"197.9"	"205.5"	"274.3"	"747.1"	"798.3"	"2466.8"	"3699.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P83916"	"Chromobox protein homolog 1 OS=Homo sapiens OX=9606 GN=CBX1 PE=1 SV=1"	"0.000"	""	"19"	"3"	"8"	"2"	"185"	"21.4"	"4.93"	"1515.75"	"15.67"	"3"	"3"	"cell organization and biogenesis;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00385, Pf01393"	"10951"	"ENSG00000108468"	"CBX1"	"hsa:10951; P23197; P83916"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"HCMV Early Events"	"2"	"0"	"356.5"	"308.1"	"287.8"	"282.3"	"255.5"	"280.3"	"346.9"	"484.9"	"438.3"	"750.8"	"1197.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WVC0"	"RNA polymerase-associated protein LEO1 OS=Homo sapiens OX=9606 GN=LEO1 PE=1 SV=1"	"0.000"	""	"12"	"6"	"12"	"6"	"666"	"75.4"	"4.51"	"2591.34"	"15.66"	"6"	"4"	"cell-cell signaling;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytoskeleton;nucleus"	"other molecular function"	"Pf04004"	"123169"	"ENSG00000166477"	"LEO1"	"hsa:123169; Q8WVC0; Q96N99"	"Endoderm differentiation"	"E3 ubiquitin ligases ubiquitinate target proteins; Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events; Formation of the beta-catenin:TCF transactivating complex"	"6"	"0"	"488.4"	"409.9"	"460.1"	"422.8"	"411.0"	"454.3"	"565.0"	"832.5"	"803.9"	"1376.7"	"1769.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6I9Y2"	"THO complex subunit 7 homolog OS=Homo sapiens OX=9606 GN=THOC7 PE=1 SV=3"	"0.000"	""	"25"	"5"	"9"	"5"	"204"	"23.7"	"5.67"	"1577.39"	"15.66"	"4"	"5"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf05615"	"80145"	"ENSG00000163634"	"THOC7"	"hsa:80145; Q6I9Y2; Q6P1L3; Q8WUF2; Q9H5H0"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"3"	"0"	"910.7"	"634.6"	"804.4"	"750.3"	"691.8"	"740.0"	"932.8"	"1298.6"	"1182.3"	"2148.9"	"3193.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z6E9"	"E3 ubiquitin-protein ligase RBBP6 OS=Homo sapiens OX=9606 GN=RBBP6 PE=1 SV=1"	"0.000"	""	"3"	"4"	"8"	"4"	"1792"	"201.4"	"9.64"	"1544.49"	"15.63"	"4"	"4"	"protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf04564, Pf08783, Pf13696"	"5930"	"ENSG00000122257"	"RBBP6"	"hsa:5930; Q147T5; Q15290; Q6DKH4; Q6P4C2; Q6YNC9; Q7Z6E8; Q7Z6E9; Q8N0V2; Q96PH3; Q9H3I8; Q9H5M5; Q9NPX4"	""	"RHOBTB1 GTPase cycle; Antigen processing: Ubiquitination & Proteasome degradation"	"2"	"0"	"439.0"	"323.5"	"427.4"	"402.1"	"391.8"	"399.8"	"507.7"	"646.1"	"639.3"	"1175.0"	"1430.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75494"	"Serine/arginine-rich splicing factor 10 OS=Homo sapiens OX=9606 GN=SRSF10 PE=1 SV=1"	"0.000"	""	"23"	"4"	"6"	"3"	"262"	"31.3"	"11.27"	"990.46"	"15.57"	"2"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"10772"	"ENSG00000188529"	"SRSF10"	"A6NFM6; A6NI42; A6NIU7; B4DJP9; hsa:10772; O60572; O75494; Q5JRH9; Q5JRI0; Q5JRI2; Q5JRI3; Q5JRI4; Q96G09; Q96P17"	"mRNA processing"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"3"	"1"	"217.7"	"178.9"	"184.1"	"197.7"	"191.5"	"178.7"	"256.8"	"401.3"	"343.6"	"617.9"	"817.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62888"	"60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2"	"0.000"	""	"42"	"4"	"11"	"4"	"115"	"12.8"	"9.63"	"1947.62"	"15.56"	"4"	"3"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01248"	"6156"	"ENSG00000156482"	"RPL30"	"B2R591; hsa:6156; P04645; P62888; Q502Z6"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"65.3"	"44.1"	"71.3"	"73.7"	"65.0"	"77.6"	"99.2"	"197.7"	"200.0"	"517.8"	"821.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4E8"	"Ubiquitin carboxyl-terminal hydrolase 15 OS=Homo sapiens OX=9606 GN=USP15 PE=1 SV=3"	"0.000"	""	"5"	"5"	"10"	"5"	"981"	"112.3"	"5.22"	"1749.75"	"15.52"	"5"	"5"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00443, Pf06337, Pf14533, Pf14836"	"9958"	"ENSG00000135655"	"USP15"	"hsa:9958; Q08AL5; Q9H8G9; Q9HCA6; Q9UNP0; Q9Y4E8; Q9Y5B5"	""	"Ub-specific processing proteases; UCH proteinases; Downregulation of TGF-beta receptor signaling"	"3"	"0"	"358.4"	"278.9"	"324.3"	"341.6"	"293.8"	"297.3"	"439.1"	"716.6"	"700.6"	"1246.0"	"1534.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4J8"	"Dystrobrevin alpha OS=Homo sapiens OX=9606 GN=DTNA PE=1 SV=2"	"0.000"	""	"8"	"5"	"8"	"5"	"743"	"83.8"	"6.89"	"1405.52"	"15.47"	"4"	"4"	"cell-cell signaling;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00569, Pf09068, Pf09069"	"1837"	"ENSG00000134769"	"DTNA"	"A8K541; A8MSZ0; A8MUY4; B4DGS6; B4DIR0; B4DIU8; hsa:1837; M0QYX6; M0R397; O15332; O15333; O75697; Q13197; Q13198; Q13199; Q13498; Q13499; Q13500; Q59GK7; Q9BS59; Q9Y4J8"	"13q12.12 copy number variation"	""	"1"	"0"	"174.9"	"142.9"	"181.9"	"174.5"	"172.8"	"154.8"	"236.1"	"442.8"	"390.2"	"871.7"	"991.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6W2J9"	"BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1"	"0.000"	""	"4"	"4"	"6"	"4"	"1755"	"192.1"	"6.48"	"878.81"	"15.44"	"2"	"4"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf12796, Pf15808, Pf16553"	"54880"	"ENSG00000183337"	"BCOR"	"D3DWB3; D3DWB4; hsa:54880; Q29RF6; Q6P4B6; Q6W2J9; Q7Z2K7; Q8TEB4; Q96DB3; Q9H232; Q9H233; Q9HCJ7; Q9NXF2"	"Ectoderm differentiation; Pathways affected in adenoid cystic carcinoma; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma"	""	"3"	"0"	"172.5"	"107.9"	"163.8"	"170.3"	"154.6"	"157.3"	"173.7"	"281.2"	"268.8"	"500.9"	"597.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UQ16"	"Dynamin-3 OS=Homo sapiens OX=9606 GN=DNM3 PE=1 SV=4"	"0.000"	""	"8"	"5"	"8"	"1"	"869"	"97.7"	"8.35"	"941.13"	"15.43"	"3"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytoskeleton;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00169, Pf00350, Pf01031, Pf02212"	"26052"	"ENSG00000197959"	"DNM3"	"A9Z1Y1; hsa:26052; O14982; O95555; Q1MTM8; Q5W129; Q6P2G1; Q9H0P3; Q9H548; Q9NQ68; Q9NQN6; Q9UQ16"	"Synaptic vesicle pathway; Alstrom syndrome; 15q25 copy number variation"	"Recycling pathway of L1; MHC class II antigen presentation; Toll Like Receptor 4 (TLR4) Cascade; Clathrin-mediated endocytosis; Retrograde neurotrophin signalling"	"8"	"0"	"0.0"	"0.0"	"2.9"	"3.2"	"3.1"	"4.6"	"6.9"	"19.0"	"16.6"	"30.3"	"43.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5S2"	"Serine/threonine-protein kinase MRCK beta OS=Homo sapiens OX=9606 GN=CDC42BPB PE=1 SV=2"	"0.000"	""	"5"	"6"	"9"	"6"	"1711"	"194.2"	"6.37"	"1585.07"	"15.43"	"5"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00130, Pf00780, Pf08826, Pf15796"	"9578"	"ENSG00000198752"	"CDC42BPB"	"A9JR72; hsa:9578; Q2L7A5; Q86TJ1; Q9ULU5; Q9Y5S2"	"VEGFA-VEGFR2 signaling; 15q11q13 copy number variation"	"CDC42 GTPase cycle; RHOQ GTPase cycle; RHOJ GTPase cycle"	"5"	"0"	"230.8"	"176.9"	"280.7"	"266.2"	"242.7"	"274.0"	"377.6"	"984.8"	"951.0"	"1541.8"	"1902.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q0VDF9"	"Heat shock 70 kDa protein 14 OS=Homo sapiens OX=9606 GN=HSPA14 PE=1 SV=1"	"0.000"	""	"8"	"3"	"7"	"3"	"509"	"54.8"	"5.59"	"1279.18"	"15.42"	"2"	"3"	"protein metabolism;other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00012"	"51182"	"ENSG00000187522"	"HSPA14"	"A8K8F8; B0YIY9; hsa:51182; Q0VDF9; Q9P0X2; Q9UI07"	"Parkin-ubiquitin proteasomal system pathway"	"Regulation of HSF1-mediated heat shock response"	"2"	"0"	"81.0"	"62.3"	"111.6"	"92.5"	"86.7"	"83.0"	"110.3"	"246.6"	"236.0"	"514.3"	"670.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13427"	"Peptidyl-prolyl cis-trans isomerase G OS=Homo sapiens OX=9606 GN=PPIG PE=1 SV=2"	"0.000"	""	"9"	"6"	"11"	"6"	"754"	"88.6"	"10.29"	"2029.71"	"15.42"	"6"	"5"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00160"	"9360"	"ENSG00000138398"	"PPIG"	"D3DPC5; D3DPC6; hsa:9360; O00706; Q13427; Q53R40; Q53SN4; Q96DG9"	""	"SARS-CoV-1 activates/modulates innate immune responses; mRNA Splicing - Major Pathway"	"2"	"0"	"351.1"	"282.9"	"353.4"	"360.9"	"336.4"	"334.5"	"470.0"	"675.6"	"620.5"	"1269.9"	"1819.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63167"	"Dynein light chain 1, cytoplasmic OS=Homo sapiens OX=9606 GN=DYNLL1 PE=1 SV=1"	"0.000"	""	"34"	"3"	"6"	"3"	"89"	"10.4"	"7.40"	"589.28"	"15.41"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01221"	"8655"	"ENSG00000088986"	"DYNLL1"	"hsa:8655; P63167; Q15701"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein; Genes related to primary cilium development (based on CRISPR); 3q29 copy number variation syndrome"	"HCMV Early Events; MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Aggrephagy; Separation of Sister Chromatids; Intraflagellar transport; Resolution of Sister Chromatid Cohesion; Recruitment of NuMA to mitotic centrosomes; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Neutrophil degranulation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Macroautophagy; Activation of BIM and translocation to mitochondria"	"27"	"0"	"354.9"	"435.5"	"369.3"	"347.6"	"364.4"	"360.6"	"465.2"	"601.2"	"573.5"	"1144.4"	"1659.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12788"	"Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2"	"0.000"	""	"7"	"4"	"10"	"4"	"808"	"89.0"	"6.90"	"1824.92"	"15.39"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00400, Pf08625"	"10607"	"ENSG00000183751"	"TBL3"	"hsa:10607; Q12788; Q59GD6; Q8IVB7; Q96A78"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"86.5"	"62.7"	"93.8"	"89.1"	"82.4"	"83.3"	"104.4"	"232.7"	"268.0"	"619.2"	"791.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15530"	"3-phosphoinositide-dependent protein kinase 1 OS=Homo sapiens OX=9606 GN=PDPK1 PE=1 SV=1"	"0.000"	""	"6"	"2"	"6"	"2"	"556"	"63.1"	"7.36"	"1594.65"	"15.32"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069, Pf14593"	"5170"	"ENSG00000140992"	"PDPK1"	"H0Y4Z0; hsa:5170; O15530; Q59EH6; Q6FI20; Q8IV52; Q9BRD5"	"MicroRNAs in cardiomyocyte hypertrophy; Integrin-mediated cell adhesion; Thyroid stimulating hormone (TSH) signaling pathway; Glioblastoma signaling pathways; B cell receptor signaling pathway; Interleukin-11 signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Cardiac hypertrophic response; Focal adhesion; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Leptin-insulin signaling overlap; PPAR signaling pathway; Endometrial cancer; PI3K-Akt signaling pathway; EGF/EGFR signaling pathway; Head and neck squamous cell carcinoma; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; Modulators of TCR signaling and T cell activation; GDNF signaling; Primary ovarian insufficiency; A network map of Macrophage-stimulating protein (MSP) signaling; ErbB signaling pathway; T-cell receptor signaling pathway; Serotonin HTR1 group and FOS pathway"	"Role of LAT2/NTAL/LAB on calcium mobilization; FCERI mediated NF-kB activation; Downstream TCR signaling; CLEC7A (Dectin-1) signaling; Constitutive Signaling by AKT1 E17K in Cancer; PIP3 activates AKT signaling; Regulation of TP53 Degradation; GPVI-mediated activation cascade; CD28 dependent PI3K/Akt signaling; G beta:gamma signalling through PI3Kgamma; RHO GTPases activate PKNs; Activation of AKT2; Integrin signaling; RSK activation; VEGFR2 mediated vascular permeability; VEGFR2 mediated cell proliferation; Estrogen-stimulated signaling through PRKCZ; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways"	"46"	"0"	"11.7"	"14.6"	"16.2"	"8.6"	"25.5"	"51.2"	"85.6"	"191.2"	"160.8"	"316.3"	"459.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NI35"	"InaD-like protein OS=Homo sapiens OX=9606 GN=PATJ PE=1 SV=3"	"0.000"	""	"2"	"4"	"7"	"4"	"1801"	"196.2"	"4.94"	"1011.08"	"15.15"	"3"	"4"	"cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	""	"Pf00595, Pf09045"	""	"ENSG00000132849"	"PATJ"	"O15249; O43742; O60833; Q5VUA5; Q5VUA6; Q5VUA7; Q5VUA8; Q5VUA9; Q5VUB0; Q8NI35; Q8WU78; Q9H3N9"	""	"Tight junction interactions; SARS-CoV-2 targets PDZ proteins in cell-cell junction"	"2"	"0"	"254.7"	"203.5"	"267.5"	"253.1"	"228.3"	"235.8"	"291.2"	"500.3"	"485.9"	"1132.8"	"1778.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62424"	"60S ribosomal protein L7a OS=Homo sapiens OX=9606 GN=RPL7A PE=1 SV=2"	"0.000"	""	"18"	"6"	"11"	"6"	"266"	"30.0"	"10.61"	"2018.13"	"15.07"	"6"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01248"	"6130"	"ENSG00000148303; ENSG00000280858"	"RPL7A"	"hsa:6130; P11518; P62424; Q5T8U4"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"412.2"	"341.3"	"448.0"	"384.7"	"405.4"	"430.8"	"562.8"	"784.0"	"777.4"	"1598.4"	"2432.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q0ZGT2"	"Nexilin OS=Homo sapiens OX=9606 GN=NEXN PE=1 SV=1"	"0.000"	""	"7"	"3"	"5"	"3"	"675"	"80.6"	"5.33"	"860.21"	"15.06"	"2"	"3"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf07679"	"91624"	"ENSG00000162614"	"NEXN"	"A0PJ84; B4DPZ7; hsa:91624; Q0D2H2; Q0ZGT2; Q14CC2; Q14CC3; Q16081; Q7Z2X0; Q96DL0; Q9Y2V1"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"157.8"	"163.1"	"168.9"	"174.6"	"176.5"	"159.1"	"223.6"	"314.1"	"312.8"	"709.3"	"1529.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05388"	"60S acidic ribosomal protein P0 OS=Homo sapiens OX=9606 GN=RPLP0 PE=1 SV=1"	"0.000"	""	"13"	"4"	"8"	"4"	"317"	"34.3"	"5.97"	"1482.04"	"15.05"	"4"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00428, Pf00466, Pf17777"	"6175"	"ENSG00000089157"	"RPLP0"	"hsa:6175; P05388; Q3B7A4; Q9BVK4"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"15"	"0"	"342.1"	"249.7"	"357.6"	"323.1"	"302.0"	"319.1"	"423.0"	"760.1"	"715.5"	"1736.3"	"2865.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43768"	"Alpha-endosulfine OS=Homo sapiens OX=9606 GN=ENSA PE=1 SV=1"	"0.000"	""	"45"	"4"	"8"	"4"	"121"	"13.4"	"7.24"	"1770.00"	"15.04"	"4"	"4"	"cell cycle OR cell proliferation;other biological processes"	"nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf04667"	"2029"	"ENSG00000143420"	"ENSA"	"A8K1Z9; E9PB69; hsa:2029; O43768; Q5T5H2; Q68D48; Q6FHW0; Q6IAM4; Q6NUL2; Q6VUC6; Q6VUC7; Q6VUC8; Q6VUC9; Q6VUD0; Q6VUD1; Q9NRZ0"	""	"MASTL Facilitates Mitotic Progression"	"1"	"0"	"145.4"	"109.2"	"140.1"	"130.4"	"126.3"	"133.2"	"158.8"	"1015.8"	"1059.6"	"3138.9"	"3895.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N163"	"Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2"	"0.000"	""	"5"	"5"	"10"	"5"	"923"	"102.8"	"5.22"	"1469.85"	"15.01"	"5"	"5"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytoskeleton;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf14443, Pf14444, Pf19256, Pf19257"	"57805"	"ENSG00000158941"	"CCAR2"	"A6NL03; B2RB79; D3DSR6; hsa:57805; Q6P0Q9; Q8N163; Q8N3G7; Q8N8M1; Q8TF34; Q9H9Q9; Q9HD12; Q9NT55"	"TAR syndrome"	"Regulation of HSF1-mediated heat shock response"	"2"	"0"	"349.4"	"267.5"	"361.6"	"475.6"	"435.0"	"335.1"	"398.5"	"568.7"	"497.5"	"1002.8"	"1430.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P10599"	"Thioredoxin OS=Homo sapiens OX=9606 GN=TXN PE=1 SV=3"	"0.000"	""	"40"	"4"	"7"	"4"	"105"	"11.7"	"4.92"	"1184.19"	"14.97"	"3"	"4"	"other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00085"	"7295"	"ENSG00000136810"	"TXN"	"B1ALW1; hsa:7295; O60744; P10599; Q53X69; Q96KI3; Q9UDG5"	"Selenium micronutrient network; Folic acid network; Selenium micronutrient network ; Folic acid network; Selenium micronutrient network; TNF-alpha signaling pathway; Complement system; Nuclear receptors meta-pathway; NRF2 pathway; VEGFA-VEGFR2 signaling; TAR syndrome"	"TP53 Regulates Metabolic Genes; Detoxification of Reactive Oxygen Species; Oxidative Stress Induced Senescence; Interconversion of nucleotide di- and triphosphates; The NLRP3 inflammasome; Purinergic signaling in leishmaniasis infection; Regulation of FOXO transcriptional activity by acetylation; Protein repair"	"19"	"0"	"472.1"	"311.9"	"629.7"	"472.9"	"444.5"	"343.4"	"501.1"	"732.2"	"676.8"	"1109.0"	"1595.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92890"	"Ubiquitin recognition factor in ER-associated degradation protein 1 OS=Homo sapiens OX=9606 GN=UFD1 PE=1 SV=3"	"0.000"	""	"16"	"4"	"8"	"4"	"307"	"34.5"	"6.70"	"1644.04"	"14.95"	"4"	"4"	"protein metabolism;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf03152"	"7353"	"ENSG00000070010"	"UFD1"	"A8MW31; hsa:7353; Q92890; Q9Y5N0"	"22q11.2 copy number variation syndrome"	"Ub-specific processing proteases; Neddylation; KEAP1-NFE2L2 pathway; Translesion Synthesis by POLH"	"5"	"0"	"274.8"	"257.4"	"274.3"	"247.6"	"260.6"	"270.9"	"323.7"	"591.2"	"627.1"	"1897.1"	"2498.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P27694"	"Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2"	"0.000"	""	"8"	"4"	"8"	"4"	"616"	"68.1"	"7.21"	"1733.59"	"14.94"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01336, Pf04057, Pf08646, Pf16900"	"6117"	"ENSG00000132383"	"RPA1"	"A8K0Y9; hsa:6117; P27694; Q59ES9"	"Homologous recombination; Retinoblastoma gene in cancer; ATR signaling; G1 to S cell cycle control; DNA replication; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"SUMOylation of DNA damage response and repair proteins; PCNA-Dependent Long Patch Base Excision Repair; Fanconi Anemia Pathway; Regulation of HSF1-mediated heat shock response; Regulation of TP53 Activity through Phosphorylation; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Meiotic recombination; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; HSF1 activation; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; Dual Incision in GG-NER; Removal of the Flap Intermediate; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"39"	"0"	"71.1"	"52.7"	"69.0"	"63.4"	"62.6"	"57.6"	"86.8"	"177.7"	"166.5"	"422.1"	"767.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52434"	"DNA-directed RNA polymerases I, II, and III subunit RPABC3 OS=Homo sapiens OX=9606 GN=POLR2H PE=1 SV=4"	"0.000"	""	"26"	"3"	"8"	"3"	"150"	"17.1"	"4.68"	"1592.50"	"14.91"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf03870"	"5437"	"ENSG00000163882"	"POLR2H"	"C9J413; C9JBJ6; C9JCU7; C9JUA8; hsa:5437; P52434; P53802; Q969R0"	"Pyrimidine metabolism; Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"Gap-filling DNA repair synthesis and ligation in TC-NER; mRNA Splicing - Major Pathway; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; Estrogen-dependent gene expression; Formation of the Early Elongation Complex; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; B-WICH complex positively regulates rRNA expression; Abortive elongation of HIV-1 transcript in the absence of Tat; Activation of anterior HOX genes in hindbrain development during early embryogenesis; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"57"	"0"	"379.7"	"310.2"	"336.3"	"342.7"	"314.6"	"325.0"	"389.3"	"749.2"	"756.1"	"1615.0"	"2284.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00422"	"Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1"	"0.000"	""	"48"	"7"	"13"	"7"	"153"	"17.6"	"9.35"	"3259.79"	"14.89"	"6"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf06487"	"10284"	"ENSG00000150459"	"SAP18"	"B2R494; hsa:10284; O00422; Q2TTR4; Q6IAW9; Q8N606; Q9UF14; X6RAL5"	"Hedgehog signaling pathway"	"Potential therapeutics for SARS; HDACs deacetylate histones; NoRC negatively regulates rRNA expression; mRNA Splicing - Major Pathway"	"5"	"0"	"1980.6"	"1610.1"	"1804.4"	"1756.3"	"1683.9"	"1800.7"	"2290.0"	"2558.3"	"2216.0"	"3282.6"	"4718.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q05397"	"Focal adhesion kinase 1 OS=Homo sapiens OX=9606 GN=PTK2 PE=1 SV=2"	"0.000"	""	"5"	"5"	"9"	"5"	"1052"	"119.2"	"6.62"	"1036.26"	"14.88"	"4"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;kinase activity;other molecular function"	"Pf00373, Pf03623, Pf07714, Pf18038"	"5747"	"ENSG00000169398"	"PTK2"	"B4E2N6; F5H4S4; hsa:5747; J3QT16; Q05397; Q14291; Q8IYN9; Q9UD85"	"Androgen receptor signaling pathway; Integrin-mediated cell adhesion; RANKL/RANK signaling pathway; Leptin signaling pathway; Prolactin signaling pathway; Corticotropin-releasing hormone signaling pathway; Alpha 6 beta 4 signaling pathway; Primary focal segmental glomerulosclerosis (FSGS); Apoptosis-related network due to altered Notch3 in ovarian cancer; Focal adhesion; Hepatocyte growth factor receptor signaling; Overview of nanoparticle effects; MFAP5-mediated ovarian cancer cell motility and invasiveness; RAC1/PAK1/p38/MMP2 pathway; Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Prion disease pathway; PI3K-Akt signaling pathway; EGF/EGFR signaling pathway; Hippo-Merlin signaling dysregulation; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Small cell lung cancer; Gastrin signaling pathway; Netrin-UNC5B signaling pathway; Pleural mesothelioma; Regulation of actin cytoskeleton; 2q13 copy number variation syndrome; TROP2 regulatory signaling; A network map of Macrophage-stimulating protein (MSP) signaling; ErbB signaling pathway"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; EPHB-mediated forward signaling; Signal regulatory protein family interactions; DCC mediated attractive signaling; RAF/MAP kinase cascade; VEGFA-VEGFR2 Pathway; Estrogen-dependent nuclear events downstream of ESR-membrane signaling; NCAM signaling for neurite out-growth; MET activates PTK2 signaling; GRB2:SOS provides linkage to MAPK signaling for Integrins ; p130Cas linkage to MAPK signaling for integrins; Apoptotic cleavage of cellular proteins"	"48"	"0"	"244.1"	"204.6"	"233.3"	"228.5"	"231.6"	"389.9"	"668.0"	"1726.9"	"1726.8"	"2754.0"	"2479.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WWM7"	"Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2"	"0.000"	""	"6"	"5"	"9"	"5"	"1075"	"113.3"	"8.59"	"1320.29"	"14.87"	"3"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf06741, Pf07145, Pf14438"	"11273"	"ENSG00000168488"	"ATXN2L"	"A8K1R6; B9EGM2; E9PAR9; hsa:11273; O95135; Q63ZY4; Q6NVJ8; Q6PJW6; Q8IU61; Q8IU95; Q8WWM3; Q8WWM4; Q8WWM5; Q8WWM6; Q8WWM7; Q99703"	"16p11.2 distal deletion syndrome"	""	"1"	"0"	"451.7"	"367.6"	"420.3"	"439.1"	"462.8"	"447.3"	"528.6"	"744.0"	"701.5"	"1546.7"	"2124.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L9B9"	"Endonuclease/exonuclease/phosphatase family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=EEPD1 PE=1 SV=2"	"0.000"	""	"8"	"3"	"5"	"3"	"569"	"62.4"	"8.41"	"679.59"	"14.82"	"2"	"3"	"DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes"	"nucleic acid binding activity"	"Pf12836"	"80820"	"ENSG00000122547"	"EEPD1"	"hsa:80820; Q7L9B9; Q96K64; Q9C0F7"	""	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"	"1"	"0"	"55.7"	"41.5"	"46.9"	"51.9"	"55.1"	"51.7"	"63.7"	"162.2"	"153.4"	"451.9"	"645.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00629"	"Importin subunit alpha-3 OS=Homo sapiens OX=9606 GN=KPNA4 PE=1 SV=1"	"0.000"	""	"11"	"3"	"4"	"2"	"521"	"57.9"	"4.96"	"591.99"	"14.80"	"1"	"3"	"cell-cell signaling;other metabolic processes;transport"	"other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00514, Pf01749, Pf16186"	"3840"	"ENSG00000186432"	"KPNA4"	"A8K4S6; D3DNM2; hsa:3840; O00190; O00629"	"Leptin signaling pathway"	"ISG15 antiviral mechanism; NS1 Mediated Effects on Host Pathways"	"3"	"0"	"23.5"	"15.9"	"21.9"	"42.3"	"22.5"	"23.7"	"27.1"	"65.3"	"62.4"	"190.6"	"313.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35249"	"Replication factor C subunit 4 OS=Homo sapiens OX=9606 GN=RFC4 PE=1 SV=2"	"0.000"	""	"15"	"5"	"10"	"5"	"363"	"39.7"	"8.02"	"1734.92"	"14.79"	"5"	"5"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00004, Pf08542"	"5984"	"ENSG00000163918"	"RFC4"	"B4DM41; D3DNV2; hsa:5984; P35249; Q6FHX7"	"Gastric cancer network 2; Retinoblastoma gene in cancer; DNA replication; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"Activation of ATR in response to replication stress; Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Polymerase switching on the C-strand of the telomere; Polymerase switching; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER"	"28"	"0"	"390.2"	"445.5"	"382.4"	"363.9"	"336.1"	"361.6"	"458.4"	"683.6"	"709.7"	"1495.2"	"1996.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99569"	"Plakophilin-4 OS=Homo sapiens OX=9606 GN=PKP4 PE=1 SV=2"	"0.000"	""	"5"	"4"	"8"	"4"	"1192"	"131.8"	"8.94"	"1562.13"	"14.78"	"4"	"4"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00514"	"8502"	"ENSG00000144283"	"PKP4"	"hsa:8502; Q86W91; Q99569"	""	"Formation of the cornified envelope; RND2 GTPase cycle; RND3 GTPase cycle; RND1 GTPase cycle"	"5"	"0"	"45.0"	"33.2"	"43.6"	"46.3"	"37.9"	"40.0"	"66.7"	"100.8"	"100.6"	"235.6"	"346.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UJS0"	"Calcium-binding mitochondrial carrier protein Aralar2 OS=Homo sapiens OX=9606 GN=SLC25A13 PE=1 SV=2"	"0.000"	""	"7"	"3"	"8"	"3"	"675"	"74.1"	"8.62"	"1661.64"	"14.77"	"3"	"3"	"other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00153"	"10165"	"ENSG00000004864"	"SLC25A13"	"hsa:10165; O14566; O14575; Q546F9; Q9NZW1; Q9UJS0; Q9UNI7"	""	"Gluconeogenesis; Mitochondrial protein import; Aspartate and asparagine metabolism"	"3"	"0"	"66.4"	"58.1"	"61.9"	"56.5"	"48.1"	"63.1"	"67.1"	"121.9"	"136.4"	"295.3"	"404.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75792"	"Ribonuclease H2 subunit A OS=Homo sapiens OX=9606 GN=RNASEH2A PE=1 SV=2"	"0.000"	""	"12"	"3"	"8"	"3"	"299"	"33.4"	"5.25"	"1463.41"	"14.72"	"3"	"3"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01351"	"10535"	"ENSG00000104889"	"RNASEH2A"	"B2RCY1; hsa:10535; O75792; Q96F11"	""	""	"0"	"0"	"130.1"	"98.0"	"149.9"	"147.9"	"128.9"	"116.0"	"168.6"	"502.4"	"609.2"	"1450.5"	"1874.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NP97"	"Dynein light chain roadblock-type 1 OS=Homo sapiens OX=9606 GN=DYNLRB1 PE=1 SV=3"	"0.000"	""	"29"	"2"	"8"	"2"	"96"	"10.9"	"7.25"	"1812.12"	"14.71"	"2"	"2"	"other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03259"	"83658"	"ENSG00000125971"	"DYNLRB1"	"B1AKR5; hsa:83658; Q5TC72; Q96IV3; Q9NP97; Q9NQM2"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein; 3q29 copy number variation syndrome"	"Intraflagellar transport"	"4"	"0"	"90.2"	"60.7"	"103.9"	"94.1"	"98.6"	"88.3"	"129.6"	"214.2"	"191.0"	"419.0"	"584.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NUU7"	"ATP-dependent RNA helicase DDX19A OS=Homo sapiens OX=9606 GN=DDX19A PE=1 SV=1"	"0.000"	""	"10"	"3"	"5"	"1"	"478"	"53.9"	"6.58"	"857.06"	"14.71"	"2"	"3"	"other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"55308"	"ENSG00000168872"	"DDX19A"	"B2RPL0; B4DRZ7; hsa:55308; Q53FM0; Q9NUU7"	""	""	"0"	"0"	"14.7"	"12.1"	"20.5"	"20.4"	"18.2"	"14.6"	"32.0"	"59.5"	"68.2"	"238.7"	"389.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6UXN9"	"WD repeat-containing protein 82 OS=Homo sapiens OX=9606 GN=WDR82 PE=1 SV=1"	"0.000"	""	"10"	"3"	"4"	"3"	"313"	"35.1"	"7.69"	"248.45"	"14.68"	"1"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00400"	"80335"	"ENSG00000164091"	"WDR82"	"A8K5R5; hsa:80335; Q6UXN9; Q8TEB2"	""	"Formation of WDR5-containing histone-modifying complexes"	"1"	"0"	"203.4"	"151.8"	"211.5"	"208.7"	"206.1"	"216.4"	"254.9"	"422.0"	"425.1"	"862.9"	"1311.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z794"	"Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3"	"0.000"	""	"5"	"3"	"8"	"1"	"578"	"61.9"	"5.99"	"1446.38"	"14.64"	"3"	"3"	"other biological processes"	"plasma membrane;cytosol;cytoskeleton"	"bone, tooth or skin structural activity"	"Pf00038, Pf16208"	"374454"	"ENSG00000189182"	"KRT77"	"hsa:374454; Q7RTS8; Q7Z794"	""	"Formation of the cornified envelope"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P16949"	"Stathmin OS=Homo sapiens OX=9606 GN=STMN1 PE=1 SV=3"	"0.000"	""	"23"	"3"	"8"	"3"	"149"	"17.3"	"5.97"	"1482.95"	"14.60"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf00836"	"3925"	"ENSG00000117632"	"STMN1"	"A2A2D1; B2R4E7; B7Z8N4; D3DPJ5; hsa:3925; P16949"	"Microtubule cytoskeleton regulation; Retinoblastoma gene in cancer; RAC1/PAK1/p38/MMP2 pathway; MAPK signaling pathway; EGF/EGFR signaling pathway; IL-18 signaling pathway"	"Nuclear signaling by ERBB4"	"7"	"0"	"280.4"	"219.0"	"306.2"	"317.3"	"278.4"	"257.3"	"336.7"	"450.9"	"410.3"	"775.6"	"2239.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TAT6"	"Nuclear protein localization protein 4 homolog OS=Homo sapiens OX=9606 GN=NPLOC4 PE=1 SV=3"	"0.000"	""	"7"	"3"	"6"	"3"	"608"	"68.1"	"6.38"	"1616.28"	"14.59"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf05020, Pf05021, Pf11543"	"55666"	"ENSG00000182446"	"NPLOC4"	"hsa:55666; Q8N3J1; Q8TAT6; Q9H8V2; Q9H964; Q9NWR5; Q9P229"	""	"Neddylation; KEAP1-NFE2L2 pathway; Translesion Synthesis by POLH"	"3"	"0"	"126.0"	"116.2"	"130.2"	"118.9"	"125.4"	"126.1"	"136.3"	"277.7"	"300.9"	"1034.7"	"1412.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14635"	"G2/mitotic-specific cyclin-B1 OS=Homo sapiens OX=9606 GN=CCNB1 PE=1 SV=1"	"0.000"	""	"7"	"3"	"8"	"3"	"433"	"48.3"	"7.47"	"1828.35"	"14.57"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00134, Pf02984"	"891"	"ENSG00000134057"	"CCNB1"	"A8K066; hsa:891; P14635; Q5TZP9"	"AMP-activated protein kinase signaling; miRNA regulation of DNA damage response; Cell cycle; Retinoblastoma gene in cancer; ATM signaling pathway; G1 to S cell cycle control; GDNF signaling; DNA damage response"	"The role of GTSE1 in G2/M progression after G2 checkpoint; Resolution of Sister Chromatid Cohesion; Nuclear Pore Complex (NPC) Disassembly; Regulation of PLK1 Activity at G2/M Transition; APC/C:Cdc20 mediated degradation of Cyclin B; Phosphorylation of the APC/C; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Cyclin A/B1/B2 associated events during G2/M transition; Transcriptional regulation by RUNX2; MASTL Facilitates Mitotic Progression; E2F-enabled inhibition of pre-replication complex formation; Golgi Cisternae Pericentriolar Stack Reorganization; Condensation of Prophase Chromosomes; Initiation of Nuclear Envelope (NE) Reformation; Polo-like kinase mediated events; Condensation of Prometaphase Chromosomes; Activation of NIMA Kinases NEK9, NEK6, NEK7; G2/M DNA replication checkpoint; Depolymerization of the Nuclear Lamina; Phosphorylation of Emi1"	"31"	"0"	"353.8"	"279.9"	"340.1"	"340.7"	"311.6"	"314.1"	"445.8"	"740.7"	"783.9"	"1460.3"	"1644.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HAW4"	"Claspin OS=Homo sapiens OX=9606 GN=CLSPN PE=1 SV=3"	"0.000"	""	"5"	"5"	"10"	"5"	"1339"	"151.0"	"4.82"	"1808.97"	"14.55"	"5"	"5"	"cell cycle OR cell proliferation;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"ER/Golgi;nucleus"	"nucleic acid binding activity;other molecular function"	""	"63967"	"ENSG00000092853"	"CLSPN"	"A6NFL4; hsa:63967; Q1RMC6; Q2KHM3; Q5VYG0; Q6P6H5; Q8IWI1; Q9HAW4"	""	"Ub-specific processing proteases; Activation of ATR in response to replication stress; Processing of DNA double-strand break ends; Apoptotic cleavage of cellular proteins"	"4"	"0"	"321.4"	"263.4"	"318.4"	"327.9"	"302.0"	"329.1"	"399.0"	"450.6"	"422.0"	"643.1"	"779.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51948"	"CDK-activating kinase assembly factor MAT1 OS=Homo sapiens OX=9606 GN=MNAT1 PE=1 SV=1"	"0.000"	""	"16"	"3"	"4"	"3"	"309"	"35.8"	"6.09"	"281.58"	"14.51"	"1"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus"	"enzyme regulator activity;other molecular function"	"Pf06391, Pf17121"	"4331"	"ENSG00000020426"	"MNAT1"	"G3V1U8; hsa:4331; P51948; Q15817; Q6ICQ7"	"Eukaryotic transcription initiation; G1 to S cell cycle control; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"RUNX1 regulates transcription of genes involved in differentiation of HSCs; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; NoRC negatively regulates rRNA expression; RNA Polymerase I Promoter Escape; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Cyclin D associated events in G1; Cyclin A/B1/B2 associated events during G2/M transition; RNA Polymerase I Transcription Initiation; RNA Polymerase I Transcription Termination; Formation of Incision Complex in GG-NER; Cyclin E associated events during G1/S transition ; Cyclin A:Cdk2-associated events at S phase entry"	"38"	"0"	"44.8"	"39.5"	"49.6"	"50.1"	"54.1"	"50.7"	"79.5"	"222.0"	"247.1"	"651.2"	"962.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92665"	"28S ribosomal protein S31, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS31 PE=1 SV=3"	"0.000"	""	"14"	"4"	"7"	"4"	"395"	"45.3"	"9.29"	"1145.83"	"14.49"	"3"	"4"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf15433"	"10240"	"ENSG00000102738"	"MRPS31"	"B2RCS3; hsa:10240; Q5VYC8; Q8WTV8; Q92665"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"264.7"	"212.8"	"264.1"	"227.2"	"241.2"	"253.9"	"322.3"	"459.2"	"469.5"	"828.5"	"1187.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q3SY69"	"Mitochondrial 10-formyltetrahydrofolate dehydrogenase OS=Homo sapiens OX=9606 GN=ALDH1L2 PE=1 SV=2"	"0.000"	""	"6"	"4"	"7"	"4"	"923"	"101.7"	"6.52"	"1059.62"	"14.44"	"3"	"4"	"other metabolic processes"	"mitochondrion;nucleus"	"other molecular function"	"Pf00171, Pf00550, Pf00551, Pf02911"	"160428"	"ENSG00000136010"	"ALDH1L2"	"hsa:160428; Q3SY68; Q3SY69; Q68D62; Q6AI55; Q8N922"	""	"Metabolism of folate and pterines"	"1"	"0"	"142.6"	"95.2"	"156.2"	"151.9"	"135.0"	"139.7"	"180.2"	"347.4"	"387.9"	"988.3"	"1453.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P33240"	"Cleavage stimulation factor subunit 2 OS=Homo sapiens OX=9606 GN=CSTF2 PE=1 SV=1"	"0.000"	""	"9"	"4"	"9"	"4"	"577"	"60.9"	"6.83"	"1309.00"	"14.43"	"3"	"4"	"other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf14304, Pf14327"	"1478"	"ENSG00000101811"	"CSTF2"	"hsa:1478; P33240; Q5H951; Q6LA74; Q8N502"	"mRNA processing"	"tRNA processing in the nucleus; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"6"	"0"	"629.2"	"427.9"	"651.4"	"561.6"	"528.4"	"530.6"	"703.9"	"937.8"	"906.7"	"1894.8"	"2486.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y520"	"Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4"	"0.000"	""	"2"	"6"	"10"	"5"	"2896"	"316.7"	"9.13"	"2027.87"	"14.39"	"6"	"4"	"cell organization and biogenesis;other biological processes"	"cytosol;other cell component"	""	"Pf07001"	"23215"	"ENSG00000117523"	"PRRC2C"	"hsa:23215; Q05DM8; Q49A39; Q6PD54; Q9H2N2; Q9HA05; Q9NSM8; Q9NXL3; Q9UF29; Q9UPQ6; Q9Y520"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"310.2"	"263.1"	"226.2"	"255.0"	"209.9"	"222.8"	"303.0"	"379.0"	"379.2"	"576.3"	"748.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60869"	"Endothelial differentiation-related factor 1 OS=Homo sapiens OX=9606 GN=EDF1 PE=1 SV=1"	"0.000"	""	"21"	"4"	"10"	"4"	"148"	"16.4"	"9.95"	"2302.18"	"14.38"	"4"	"2"	"other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01381, Pf08523"	"8721"	"ENSG00000107223"	"EDF1"	"hsa:8721; O60869; Q5T5T2; Q9UIM1"	""	""	"0"	"0"	"1355.1"	"1212.1"	"1321.9"	"1199.9"	"1357.3"	"1271.4"	"1663.8"	"1594.1"	"1396.0"	"1377.5"	"1519.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5T200"	"Zinc finger CCCH domain-containing protein 13 OS=Homo sapiens OX=9606 GN=ZC3H13 PE=1 SV=1"	"0.000"	""	"3"	"4"	"8"	"4"	"1668"	"196.5"	"9.42"	"1647.60"	"14.36"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00642"	"23091"	"ENSG00000123200"	"ZC3H13"	"A2A323; hsa:23091; O94936; Q5T1Z9; Q5T200; Q7Z7J3; Q8NDT6; Q9H0L6"	""	""	"0"	"0"	"190.8"	"143.2"	"144.2"	"149.0"	"140.1"	"144.3"	"203.4"	"324.5"	"330.3"	"662.6"	"922.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46783"	"40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1"	"0.000"	""	"42"	"7"	"19"	"6"	"165"	"18.9"	"10.15"	"4698.25"	"14.36"	"7"	"4"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf03501"	"6204"	"ENSG00000124614"	"RPS10"	"B2R4E3; hsa:6204; P46783; Q5TZC0"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"1713.8"	"1827.7"	"1807.9"	"1644.5"	"1763.1"	"1666.1"	"2085.3"	"2164.4"	"2023.4"	"2694.5"	"3074.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P10606"	"Cytochrome c oxidase subunit 5B, mitochondrial OS=Homo sapiens OX=9606 GN=COX5B PE=1 SV=2"	"0.000"	""	"45"	"5"	"8"	"5"	"129"	"13.7"	"8.81"	"1576.25"	"14.36"	"4"	"4"	"other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf01215"	"1329"	"ENSG00000135940"	"COX5B"	"hsa:1329; P10606; Q53YB7; Q96J18; Q99610"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex IV assembly; 5q35 copy number variation"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"7"	"0"	"249.3"	"225.5"	"253.8"	"244.6"	"235.3"	"233.2"	"282.4"	"512.6"	"520.6"	"1421.9"	"2019.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55884"	"Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3"	"0.000"	""	"7"	"3"	"5"	"3"	"814"	"92.4"	"5.00"	"772.37"	"14.35"	"2"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08662"	"8662"	"ENSG00000106263"	"EIF3B"	"A4D208; hsa:8662; P55884; Q2NL77; Q9UMF9"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"8"	"0"	"44.1"	"33.1"	"54.6"	"56.1"	"56.2"	"64.5"	"63.4"	"117.8"	"141.2"	"247.6"	"416.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BVP2"	"Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2"	"0.000"	""	"13"	"5"	"8"	"5"	"549"	"62.0"	"9.16"	"1423.82"	"14.34"	"4"	"4"	"cell cycle OR cell proliferation;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01926, Pf08701"	"26354"	"ENSG00000163938"	"GNL3"	"B2RDC1; hsa:26354; Q5PU80; Q96SV6; Q96SV7; Q9BVP2; Q9UJY0"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"94.7"	"81.1"	"96.7"	"90.9"	"90.1"	"91.0"	"122.3"	"254.7"	"255.9"	"581.4"	"876.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P37108"	"Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2"	"0.000"	""	"40"	"7"	"12"	"7"	"136"	"14.6"	"10.04"	"2801.99"	"14.34"	"6"	"4"	"transport"	"non-structural extracellular;cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02290"	"6727"	"ENSG00000140319"	"SRP14"	"B5BUF5; hsa:6727; P37108; Q6B0K5; Q96Q14"	""	"Neutrophil degranulation; SRP-dependent cotranslational protein targeting to membrane"	"2"	"0"	"2385.0"	"1813.7"	"2073.6"	"2017.2"	"1911.9"	"1933.7"	"2701.4"	"2787.0"	"2422.9"	"2122.0"	"3212.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92620"	"Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 OS=Homo sapiens OX=9606 GN=DHX38 PE=1 SV=2"	"0.000"	""	"5"	"4"	"8"	"4"	"1227"	"140.4"	"6.54"	"1515.98"	"14.31"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"9785"	"ENSG00000140829"	"DHX38"	"B4DVG8; D3DWS7; hsa:9785; O75212; Q92620; Q96HN7"	"mRNA processing"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"5"	"0"	"155.5"	"121.5"	"169.8"	"159.7"	"157.2"	"147.2"	"183.4"	"312.0"	"310.1"	"598.3"	"739.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62913"	"60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2"	"0.000"	""	"16"	"3"	"7"	"3"	"178"	"20.2"	"9.60"	"1120.43"	"14.31"	"2"	"3"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00281, Pf00673"	"6135"	"ENSG00000142676"	"RPL11"	"hsa:6135; P25121; P39026; P62913; Q8TDH2; Q9Y674"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"537.7"	"427.5"	"545.3"	"506.4"	"496.2"	"520.3"	"721.1"	"828.5"	"842.2"	"1263.1"	"1376.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14241"	"Elongin-A OS=Homo sapiens OX=9606 GN=ELOA PE=1 SV=2"	"0.000"	""	"7"	"5"	"10"	"5"	"798"	"89.9"	"9.57"	"2705.41"	"14.29"	"5"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf06881, Pf08711"	"6924"	"ENSG00000011007"	"ELOA"	"B2R7Q8; hsa:6924; Q14241; Q8IXH1"	"VEGFA-VEGFR2 signaling; 10q11.21q11.23 copy number variation syndrome"	"Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes"	"13"	"0"	"462.0"	"366.3"	"405.5"	"421.9"	"403.4"	"465.5"	"610.8"	"1289.8"	"1343.4"	"1687.0"	"1594.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52907"	"F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3"	"0.000"	""	"17"	"3"	"6"	"3"	"286"	"32.9"	"5.69"	"1204.95"	"14.29"	"3"	"3"	"cell organization and biogenesis"	"non-structural extracellular;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf01267"	"829"	"ENSG00000116489"	"CAPZA1"	"hsa:829; P52907; Q53FQ6; Q6FHD5"	""	"Sensory processing of sound by inner hair cells of the cochlea; MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Factors involved in megakaryocyte development and platelet production; Advanced glycosylation endproduct receptor signaling"	"8"	"0"	"50.8"	"32.5"	"57.7"	"56.9"	"56.6"	"54.1"	"77.3"	"173.1"	"177.3"	"443.8"	"680.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75592"	"E3 ubiquitin-protein ligase MYCBP2 OS=Homo sapiens OX=9606 GN=MYCBP2 PE=1 SV=4"	"0.000"	""	"1"	"4"	"10"	"4"	"4678"	"513.3"	"7.02"	"1632.36"	"14.27"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00415, Pf03256, Pf08005, Pf08239, Pf13540, Pf13639"	"23077"	"ENSG00000005810"	"MYCBP2"	"A6NJC6; hsa:23077; O75592; Q5JSX8; Q5VZN6; Q6PIB6; Q9UQ11; Q9Y6E4"	"3q29 copy number variation syndrome"	""	"1"	"0"	"236.7"	"216.1"	"232.9"	"231.0"	"204.8"	"222.7"	"278.4"	"511.5"	"509.3"	"858.4"	"1167.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q01844"	"RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1"	"0.000"	""	"8"	"4"	"7"	"4"	"656"	"68.4"	"9.33"	"1184.58"	"14.27"	"3"	"4"	"other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00076, Pf00641"	"2130"	"ENSG00000182944"	"EWSR1"	"B0QYK1; hsa:2130; Q01844; Q5THL0; Q92635; Q96FE8; Q96MN4; Q96MX4; Q9BWA2"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"402.9"	"370.3"	"397.0"	"381.9"	"395.3"	"403.6"	"479.0"	"709.9"	"630.4"	"1194.0"	"1556.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99567"	"Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2"	"0.000"	""	"7"	"4"	"7"	"4"	"741"	"83.5"	"5.69"	"1509.83"	"14.23"	"3"	"4"	"cell cycle OR cell proliferation;other metabolic processes;transport"	"cytosol;nucleus"	"other molecular function"	"Pf10168"	"4927"	"ENSG00000108559"	"NUP88"	"D3DTM2; hsa:4927; Q99567; Q9BWE5"	"Ciliary landscape"	"ISG15 antiviral mechanism; NS1 Mediated Effects on Host Pathways; HCMV Early Events; SUMOylation of DNA replication proteins; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; SUMOylation of DNA damage response and repair proteins; Transport of Mature mRNA derived from an Intron-Containing Transcript; HCMV Late Events; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"29"	"0"	"297.2"	"190.2"	"290.5"	"275.2"	"225.9"	"255.6"	"337.5"	"506.0"	"584.1"	"1203.1"	"1670.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5T653"	"39S ribosomal protein L2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL2 PE=1 SV=2"	"0.000"	""	"17"	"3"	"5"	"3"	"305"	"33.3"	"11.30"	"996.11"	"14.21"	"2"	"3"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf00181, Pf03947"	"51069"	"ENSG00000112651"	"MRPL2"	"B2RC56; hsa:51069; Q5T653; Q8WUL1; Q96Q56; Q9Y311"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"42.2"	"30.5"	"39.7"	"35.8"	"40.2"	"32.3"	"46.5"	"80.0"	"70.8"	"149.7"	"250.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14715"	"RANBP2-like and GRIP domain-containing protein 8 OS=Homo sapiens OX=9606 GN=RGPD8 PE=1 SV=2"	"0.000"	""	"4"	"7"	"12"	"1"	"1765"	"198.9"	"6.49"	"2633.12"	"14.19"	"7"	"3"	"transport"	"nucleus;other cell component"	"other molecular function"	"Pf00638, Pf01465, Pf16704"	"727851"	"ENSG00000169629"	"RGPD8"	"hsa:727851; O14715; Q5CZA8"	"2q13 copy number variation syndrome"	""	"1"	"0"	"31.9"	"20.5"	"23.9"	"29.3"	"34.0"	"28.9"	"37.7"	"55.6"	"57.6"	"120.3"	"229.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25786"	"Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1"	"0.000"	""	"16"	"3"	"6"	"3"	"263"	"29.5"	"6.61"	"712.43"	"14.19"	"2"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00227, Pf10584"	"5682"	"ENSG00000129084"	"PSMA1"	"A8K400; hsa:5682; P25786; Q53YE8; Q9BRV9"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"ER-Phagosome pathway; Ub-specific processing proteases; MAPK6/MAPK4 signaling; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; UCH proteinases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"62"	"0"	"202.7"	"172.3"	"248.8"	"216.3"	"207.8"	"224.3"	"265.5"	"395.0"	"396.4"	"976.4"	"1839.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94901"	"SUN domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SUN1 PE=1 SV=3"	"0.000"	""	"6"	"3"	"6"	"3"	"812"	"90.0"	"7.08"	"1501.03"	"14.17"	"3"	"3"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"111.2"	"86.7"	"125.7"	"117.4"	"120.9"	"110.3"	"148.3"	"248.4"	"257.0"	"526.9"	"645.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UNH7"	"Sorting nexin-6 OS=Homo sapiens OX=9606 GN=SNX6 PE=1 SV=1"	"0.000"	""	"11"	"4"	"7"	"4"	"406"	"46.6"	"6.16"	"1077.97"	"14.16"	"3"	"4"	"transport;other biological processes"	"other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00787, Pf09325"	"58533"	"ENSG00000129515"	"SNX6"	"C0H5W9; hsa:58533; Q9UNH7; Q9Y449"	""	""	"0"	"0"	"146.9"	"109.8"	"138.3"	"122.6"	"110.9"	"132.8"	"161.3"	"468.5"	"465.6"	"1877.5"	"3065.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14166"	"Tubulin--tyrosine ligase-like protein 12 OS=Homo sapiens OX=9606 GN=TTLL12 PE=1 SV=2"	"0.000"	""	"9"	"3"	"4"	"3"	"644"	"74.4"	"5.53"	"457.59"	"14.15"	"1"	"3"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03133"	"23170"	"ENSG00000100304"	"TTLL12"	"hsa:23170; Q14166; Q20WK5; Q9UGU3"	""	"Carboxyterminal post-translational modifications of tubulin"	"1"	"0"	"156.7"	"126.7"	"171.6"	"172.4"	"143.7"	"129.4"	"183.5"	"293.6"	"291.3"	"509.2"	"775.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15031"	"Probable leucine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=LARS2 PE=1 SV=2"	"0.000"	""	"5"	"4"	"8"	"4"	"903"	"101.9"	"8.22"	"893.92"	"14.15"	"3"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00133, Pf08264"	"23395"	"ENSG00000011376"	"LARS2"	"hsa:23395; Q15031"	"Amino acid metabolism; IL-18 signaling pathway; Primary ovarian insufficiency"	"Mitochondrial tRNA aminoacylation"	"4"	"0"	"207.6"	"162.7"	"196.3"	"200.8"	"190.8"	"206.2"	"234.5"	"535.3"	"550.2"	"1164.1"	"1498.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y606"	"tRNA pseudouridine synthase A OS=Homo sapiens OX=9606 GN=PUS1 PE=1 SV=3"	"0.000"	""	"16"	"5"	"8"	"5"	"427"	"47.4"	"8.41"	"1375.41"	"14.14"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01416"	"80324"	"ENSG00000177192"	"PUS1"	"A8K877; B3KQC1; hsa:80324; Q8WYT2; Q9BU44; Q9Y606"	""	""	"0"	"0"	"98.6"	"69.2"	"88.9"	"86.3"	"103.3"	"106.5"	"122.7"	"280.6"	"307.3"	"506.5"	"486.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14CX7"	"N-alpha-acetyltransferase 25, NatB auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA25 PE=1 SV=1"	"0.000"	""	"6"	"5"	"9"	"5"	"972"	"112.2"	"6.64"	"1783.47"	"14.12"	"5"	"4"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;other cell component"	""	"Pf09797"	"80018"	"ENSG00000111300"	"NAA25"	"A0JLU7; hsa:80018; Q14CX7; Q6MZH1; Q7Z4N6; Q9H911"	""	""	"0"	"0"	"68.5"	"46.5"	"94.9"	"80.0"	"73.3"	"102.6"	"150.0"	"792.4"	"771.5"	"1781.0"	"1934.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A6NHR9"	"Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2"	"0.000"	""	"2"	"4"	"7"	"4"	"2005"	"226.2"	"7.30"	"1384.21"	"14.11"	"3"	"4"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06470, Pf13589"	"23347"	"ENSG00000101596"	"SMCHD1"	"A6NHR9; hsa:23347; O75141; Q6AHX6; Q6ZTQ8; Q9H6Q2; Q9UG39"	""	""	"0"	"0"	"203.2"	"157.6"	"229.1"	"194.1"	"198.8"	"207.6"	"262.9"	"405.9"	"391.3"	"780.4"	"1161.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P36542"	"ATP synthase subunit gamma, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1C PE=1 SV=1"	"0.000"	""	"19"	"6"	"11"	"6"	"298"	"33.0"	"9.22"	"1610.72"	"14.07"	"6"	"4"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf00231"	"509"	"ENSG00000165629"	"ATP5F1C"	"A8KA31; hsa:509; P36542; Q5VYP3; Q6I9V2; Q96AS8"	"Electron transport chain: OXPHOS system in mitochondria"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"3"	"0"	"315.3"	"223.4"	"313.6"	"306.5"	"284.4"	"299.8"	"388.9"	"814.2"	"795.6"	"2051.1"	"2751.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P27797"	"Calreticulin OS=Homo sapiens OX=9606 GN=CALR PE=1 SV=1"	"0.000"	""	"17"	"5"	"7"	"5"	"417"	"48.1"	"4.44"	"847.11"	"14.06"	"3"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;extracellular matrix;plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00262"	"811"	"ENSG00000179218"	"CALR"	"hsa:811; P27797; Q6IAT4; Q9UDG2"	"Androgen receptor signaling pathway; Complement system; Photodynamic therapy-induced unfolded protein response; VEGFA-VEGFR2 signaling; GDNF signaling; Calcium regulation in cardiac cells"	"Scavenging by Class A Receptors; Scavenging by Class F Receptors; ER-Phagosome pathway; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Assembly of Viral Components at the Budding Site; ATF6 (ATF6-alpha) activates chaperone genes; Calnexin/calreticulin cycle"	"13"	"0"	"746.7"	"555.1"	"572.4"	"586.8"	"516.1"	"582.8"	"756.1"	"954.1"	"897.2"	"1185.6"	"1367.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08559"	"Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial OS=Homo sapiens OX=9606 GN=PDHA1 PE=1 SV=3"	"0.000"	""	"17"	"5"	"11"	"5"	"390"	"43.3"	"8.06"	"2095.75"	"14.02"	"5"	"5"	"other metabolic processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00676"	"5160"	"ENSG00000131828"	"PDHA1"	"A5YVE9; B2R5P7; B7Z3T7; B7Z3X5; hsa:5160; P08559; Q53H41; Q5JPT8; Q9NP12; Q9UBJ8; Q9UBU0; Q9UNG4; Q9UNG5"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Lipid metabolism pathway; PI3K/AKT/mTOR - vitamin D3 signaling; Metabolic reprogramming in colon cancer; Thiamine metabolic pathways; TCA cycle in senescence; Neuroinflammation and glutamatergic signaling; Acetylcholine synthesis; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"Glyoxylate metabolism and glycine degradation; Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid"	"15"	"0"	"273.5"	"198.6"	"285.7"	"258.0"	"264.0"	"247.3"	"345.3"	"534.8"	"493.9"	"1165.3"	"1464.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UHR5"	"SAP30-binding protein OS=Homo sapiens OX=9606 GN=SAP30BP PE=1 SV=1"	"0.000"	""	"14"	"4"	"8"	"4"	"308"	"33.9"	"4.84"	"1735.87"	"14.02"	"4"	"4"	"other biological processes"	"cytoskeleton;nucleus"	""	"Pf07818"	"29115"	"ENSG00000161526"	"SAP30BP"	"B3KML7; hsa:29115; Q8N1R5; Q8TDR8; Q96D27; Q9UHR5"	""	"NoRC negatively regulates rRNA expression"	"1"	"0"	"221.6"	"194.9"	"217.4"	"194.2"	"199.3"	"206.0"	"270.0"	"379.1"	"357.5"	"707.0"	"1089.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P17980"	"26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3 PE=1 SV=3"	"0.000"	""	"15"	"4"	"8"	"4"	"439"	"49.2"	"5.24"	"2590.88"	"14.00"	"4"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf16450, Pf17862"	"5702"	"ENSG00000165916"	"PSMC3"	"B2R8V1; hsa:5702; P17980; Q3B757; Q3B865; Q53HU5; Q6GPG8; Q6IBS1; Q96HD3"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Neutrophil degranulation; Asymmetric localization of PCP proteins; Degradation of DVL; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Regulation of expression of SLITs and ROBOs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Degradation of AXIN; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"64"	"0"	"250.8"	"200.4"	"233.6"	"202.6"	"204.5"	"213.2"	"279.0"	"367.7"	"345.2"	"663.7"	"1449.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P04843"	"Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1"	"0.000"	""	"7"	"4"	"6"	"4"	"607"	"68.5"	"6.38"	"877.31"	"14.00"	"2"	"4"	"protein metabolism;other metabolic processes"	"other membranes;cytosol;ER/Golgi;other cell component"	""	"Pf04597"	"6184"	"ENSG00000163902"	"RPN1"	"B2R5Z0; D3DNB6; hsa:6184; P04843; Q68DT1"	"Proteasome degradation; N-glycan biosynthesis"	"SRP-dependent cotranslational protein targeting to membrane; Asparagine N-linked glycosylation; Maturation of spike protein"	"5"	"0"	"169.2"	"147.4"	"197.6"	"186.7"	"185.3"	"175.5"	"236.4"	"529.5"	"519.9"	"1563.5"	"2420.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22087"	"rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2"	"0.000"	""	"12"	"3"	"6"	"3"	"321"	"33.8"	"10.18"	"1424.57"	"13.97"	"3"	"3"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf01269"	"2091"	"ENSG00000105202; ENSG00000280548"	"FBL"	"B5BUE8; hsa:2091; O75259; P22087; Q6IAT5; Q9UPI6"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"367.7"	"319.9"	"347.0"	"324.0"	"293.8"	"321.8"	"435.6"	"540.8"	"537.2"	"998.2"	"1697.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9C005"	"Protein dpy-30 homolog OS=Homo sapiens OX=9606 GN=DPY30 PE=1 SV=1"	"0.000"	""	"33"	"3"	"7"	"3"	"99"	"11.2"	"4.88"	"1798.74"	"13.89"	"3"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport"	"ER/Golgi;nucleus"	"other molecular function"	"Pf05186"	"84661"	"ENSG00000162961"	"DPY30"	"D6W578; hsa:84661; Q9C005"	"Kleefstra syndrome"	"Activation of anterior HOX genes in hindbrain development during early embryogenesis; PKMTs methylate histone lysines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Formation of WDR5-containing histone-modifying complexes"	"5"	"0"	"169.4"	"132.2"	"175.3"	"176.1"	"169.8"	"162.6"	"215.7"	"383.2"	"414.5"	"1150.5"	"1889.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBQ5"	"Eukaryotic translation initiation factor 3 subunit K OS=Homo sapiens OX=9606 GN=EIF3K PE=1 SV=1"	"0.000"	""	"20"	"3"	"6"	"3"	"218"	"25.0"	"4.93"	"1275.66"	"13.85"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf10075"	"27335"	"ENSG00000178982; ENSG00000282986"	"EIF3K"	"A8K0I9; B7ZAM9; hsa:27335; Q96IQ0; Q9UBQ5; Q9Y6D1"	""	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"6"	"0"	"151.2"	"150.9"	"136.0"	"137.9"	"132.4"	"123.9"	"179.4"	"356.6"	"330.8"	"886.1"	"2571.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKM9"	"RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1"	"0.000"	""	"18"	"5"	"7"	"5"	"306"	"32.4"	"9.17"	"1450.26"	"13.81"	"4"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00076"	"22913"	"ENSG00000125970"	"RALY"	"hsa:22913; Q14621; Q2M365; Q5QPL8; Q9BQX6; Q9UJE3; Q9UKM9"	""	""	"0"	"0"	"611.9"	"408.0"	"647.3"	"522.5"	"536.3"	"564.5"	"725.3"	"1191.7"	"1058.9"	"2190.4"	"3225.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q02809"	"Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 OS=Homo sapiens OX=9606 GN=PLOD1 PE=1 SV=2"	"0.000"	""	"6"	"3"	"6"	"3"	"727"	"83.5"	"6.95"	"1175.11"	"13.76"	"3"	"3"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf03171"	"5351"	"ENSG00000083444"	"PLOD1"	"B4DR87; hsa:5351; Q02809; Q96AV9; Q9H132"	"Type I collagen synthesis in the context of osteogenesis imperfecta"	"Collagen biosynthesis and modifying enzymes"	"2"	"0"	"109.2"	"74.4"	"116.5"	"118.2"	"98.0"	"114.7"	"137.0"	"239.7"	"245.9"	"645.8"	"972.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z417"	"Nuclear fragile X mental retardation-interacting protein 2 OS=Homo sapiens OX=9606 GN=NUFIP2 PE=1 SV=1"	"0.000"	""	"11"	"5"	"6"	"5"	"695"	"76.1"	"8.70"	"921.69"	"13.73"	"3"	"3"	""	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity"	"Pf15293"	"57532"	"ENSG00000108256"	"NUFIP2"	"A1L3A6; A1L3A7; hsa:57532; Q7Z417; Q9P2M5"	""	""	"0"	"0"	"498.2"	"397.3"	"441.9"	"423.1"	"395.6"	"410.0"	"501.4"	"693.8"	"677.7"	"1014.8"	"1201.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NU22"	"Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2"	"0.000"	""	"1"	"7"	"11"	"7"	"5596"	"632.4"	"5.68"	"2417.94"	"13.68"	"7"	"4"	"cell organization and biogenesis;transport"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf07728, Pf17865, Pf17867"	"23195"	"ENSG00000112159; ENSG00000288121"	"MDN1"	"hsa:23195; O15019; Q5T794; Q9NU22"	""	""	"0"	"0"	"282.1"	"209.9"	"247.9"	"239.1"	"242.3"	"257.2"	"315.8"	"757.7"	"827.1"	"1880.3"	"2567.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NX58"	"Cell growth-regulating nucleolar protein OS=Homo sapiens OX=9606 GN=LYAR PE=1 SV=2"	"0.000"	""	"12"	"4"	"8"	"4"	"379"	"43.6"	"9.54"	"1370.97"	"13.67"	"4"	"4"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"341.7"	"279.5"	"359.7"	"335.4"	"355.6"	"373.0"	"482.6"	"794.1"	"700.4"	"1365.3"	"1556.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P41214"	"Eukaryotic translation initiation factor 2D OS=Homo sapiens OX=9606 GN=EIF2D PE=1 SV=3"	"0.000"	""	"9"	"4"	"7"	"4"	"584"	"64.7"	"7.65"	"1067.08"	"13.65"	"3"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01253, Pf17832"	"1939"	"ENSG00000143486"	"EIF2D"	"hsa:1939; P41214; Q5SY40; Q8IXV3; Q96DG3; Q96TG7; Q9NR27; Q9NSN0; Q9NV18; Q9NZ21"	""	""	"0"	"0"	"187.9"	"158.5"	"194.6"	"186.4"	"179.8"	"183.9"	"214.7"	"309.1"	"350.9"	"509.5"	"542.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75663"	"TIP41-like protein OS=Homo sapiens OX=9606 GN=TIPRL PE=1 SV=2"	"0.000"	""	"17"	"4"	"8"	"4"	"272"	"31.4"	"5.91"	"1429.61"	"13.63"	"4"	"4"	"stress response;signal transduction;other biological processes"	"cytosol"	""	"Pf04176"	"261726"	"ENSG00000143155"	"TIPRL"	"B2R8V3; hsa:261726; O75663; Q5HYB2; Q8IZ86"	"Ciliary landscape"	""	"1"	"0"	"495.9"	"423.7"	"480.0"	"460.5"	"450.8"	"466.0"	"575.2"	"859.9"	"774.8"	"1357.9"	"1972.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q01484"	"Ankyrin-2 OS=Homo sapiens OX=9606 GN=ANK2 PE=1 SV=4"	"0.000"	""	"1"	"5"	"9"	"3"	"3957"	"433.4"	"5.14"	"1539.26"	"13.63"	"5"	"4"	"cell-cell signaling;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00023, Pf00531, Pf00791, Pf12796, Pf17809"	"287"	"ENSG00000145362"	"ANK2"	"hsa:287; Q01484; Q01485; Q08AC7; Q08AC8; Q7Z3L5"	""	"Interaction between L1 and Ankyrins; COPI-mediated anterograde transport"	"2"	"0"	"49.6"	"38.3"	"36.5"	"46.0"	"41.5"	"40.4"	"46.0"	"97.2"	"106.6"	"235.0"	"274.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q06330"	"Recombining binding protein suppressor of hairless OS=Homo sapiens OX=9606 GN=RBPJ PE=1 SV=3"	"0.000"	""	"13"	"4"	"5"	"4"	"500"	"55.6"	"7.18"	"305.72"	"13.59"	"1"	"4"	"cell cycle OR cell proliferation;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09270, Pf09271, Pf20144"	"3516"	"ENSG00000168214"	"RBPJ"	"B4DY22; hsa:3516; Q06330; Q5XKH9; Q6P1N3"	"Neural crest differentiation; Notch signaling; Canonical and non-canonical Notch signaling; PTF1A related regulatory pathway; Epithelial to mesenchymal transition in colorectal cancer; Osteoblast differentiation and related diseases; Genetic causes of porto-sinusoidal vascular disease; Notch signaling pathway"	"Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; NOTCH1 Intracellular Domain Regulates Transcription; Notch-HLH transcription pathway; Somitogenesis; Formation of paraxial mesoderm; Pre-NOTCH Transcription and Translation; NOTCH3 Intracellular Domain Regulates Transcription; Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells; NOTCH2 intracellular domain regulates transcription; NOTCH4 Intracellular Domain Regulates Transcription; RUNX3 regulates NOTCH signaling"	"20"	"0"	"96.2"	"71.5"	"108.8"	"102.8"	"102.3"	"111.3"	"136.8"	"544.8"	"555.3"	"880.3"	"728.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13347"	"Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens OX=9606 GN=EIF3I PE=1 SV=1"	"0.000"	""	"14"	"4"	"8"	"4"	"325"	"36.5"	"5.64"	"1460.54"	"13.56"	"4"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf00400"	"8668"	"ENSG00000084623"	"EIF3I"	"hsa:8668; Q13347"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"8"	"0"	"250.7"	"196.6"	"281.2"	"249.0"	"251.9"	"238.9"	"289.6"	"469.8"	"433.3"	"1064.4"	"2656.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61289"	"Proteasome activator complex subunit 3 OS=Homo sapiens OX=9606 GN=PSME3 PE=1 SV=1"	"0.000"	""	"24"	"5"	"8"	"5"	"254"	"29.5"	"5.95"	"1546.35"	"13.54"	"4"	"4"	"cell cycle OR cell proliferation;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02251, Pf02252"	"10197"	"ENSG00000131467"	"PSME3"	"A8K9A3; hsa:10197; O35563; P61289; P97373; Q12920; Q13172; Q9BQD9"	"Proteasome degradation"	"ER-Phagosome pathway; Separation of Sister Chromatids; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"60"	"0"	"276.3"	"192.9"	"312.3"	"250.2"	"262.4"	"293.3"	"379.3"	"789.6"	"745.7"	"2236.3"	"3829.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P80723"	"Brain acid soluble protein 1 OS=Homo sapiens OX=9606 GN=BASP1 PE=1 SV=2"	"0.000"	""	"30"	"5"	"9"	"5"	"227"	"22.7"	"4.63"	"2299.47"	"13.52"	"4"	"4"	"developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05466"	"10409"	"ENSG00000176788"	"BASP1"	"B4DJA8; D3DTD5; hsa:10409; O43596; P80723; Q5U0S0; Q9BWA5"	""	"RHOF GTPase cycle"	"1"	"0"	"213.0"	"241.7"	"206.1"	"203.1"	"214.8"	"222.9"	"253.8"	"563.6"	"543.5"	"1697.7"	"3007.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96HC4"	"PDZ and LIM domain protein 5 OS=Homo sapiens OX=9606 GN=PDLIM5 PE=1 SV=5"	"0.000"	""	"5"	"2"	"5"	"2"	"596"	"63.9"	"8.21"	"1237.67"	"13.50"	"1"	"2"	"cell organization and biogenesis;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412, Pf00595, Pf15936"	"10611"	"ENSG00000163110"	"PDLIM5"	"A8K6F9; D6RB78; E9PBF5; hsa:10611; O60705; Q56VN4; Q5UW38; Q8WVK0; Q96HC4"	"Extracellular vesicles in the crosstalk of cardiac cells"	"Neurexins and neuroligins"	"2"	"0"	"126.3"	"122.8"	"121.1"	"110.3"	"108.1"	"116.1"	"136.5"	"261.5"	"290.5"	"621.2"	"897.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14247"	"Src substrate cortactin OS=Homo sapiens OX=9606 GN=CTTN PE=1 SV=2"	"0.000"	""	"9"	"4"	"8"	"4"	"550"	"61.5"	"5.40"	"1684.60"	"13.49"	"4"	"4"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf02218, Pf14604"	"2017"	"ENSG00000085733; ENSG00000288401"	"CTTN"	"hsa:2017; Q14247; Q8N707; Q96H99"	"Pathogenic Escherichia coli infection; Hepatitis C and hepatocellular carcinoma"	"Clathrin-mediated endocytosis; RHO GTPases activate PAKs"	"4"	"0"	"292.4"	"246.4"	"257.3"	"244.5"	"261.3"	"260.7"	"333.1"	"882.6"	"875.8"	"3095.3"	"5097.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62333"	"26S proteasome regulatory subunit 10B OS=Homo sapiens OX=9606 GN=PSMC6 PE=1 SV=1"	"0.000"	""	"10"	"3"	"6"	"3"	"389"	"44.1"	"7.49"	"1268.88"	"13.43"	"3"	"3"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf16450, Pf17862"	"5706"	"ENSG00000100519"	"PSMC6"	"B2R975; hsa:5706; P49719; P62333; Q6IBU3; Q92524"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Ciliary landscape; Alzheimer's disease"	"The role of GTSE1 in G2/M progression after G2 checkpoint; Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; SARS-CoV-1 targets host intracellular signalling and regulatory pathways"	"65"	"0"	"143.9"	"119.0"	"167.2"	"150.5"	"150.7"	"146.8"	"169.1"	"300.5"	"272.6"	"599.8"	"1172.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13045"	"Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2"	"0.000"	""	"4"	"4"	"7"	"4"	"1269"	"144.7"	"6.05"	"1503.47"	"13.43"	"4"	"3"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00626, Pf12799, Pf13855"	"2314"	"ENSG00000177731; ENSG00000284571"	"FLII"	"B4DIL0; F5H407; hsa:2314; J3QLG3; Q13045"	"VEGFA-VEGFR2 signaling; Smith-Magenis and Potocki-Lupski syndrome copy number variation"	""	"2"	"0"	"76.8"	"70.1"	"90.5"	"91.3"	"93.4"	"69.7"	"116.3"	"253.4"	"267.5"	"915.7"	"1438.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P28331"	"NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS1 PE=1 SV=3"	"0.000"	""	"6"	"5"	"10"	"5"	"727"	"79.4"	"6.23"	"1479.99"	"13.42"	"5"	"5"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00384, Pf09326, Pf10588, Pf13510"	"4719"	"ENSG00000023228; ENSG00000283447"	"NDUFS1"	"B4DIN9; B4DJA0; B4DPG1; B4DUC1; E7ENF3; hsa:4719; P28331; Q53TR8; Q8N1C4; Q8TCC9"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"200.3"	"155.7"	"208.8"	"200.4"	"204.5"	"196.6"	"269.6"	"650.2"	"690.3"	"1631.3"	"2032.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NW82"	"WD repeat-containing protein 70 OS=Homo sapiens OX=9606 GN=WDR70 PE=1 SV=1"	"0.000"	""	"8"	"4"	"8"	"4"	"654"	"73.2"	"6.33"	"1608.82"	"13.40"	"4"	"4"	""	"nucleus;other cell component"	"other molecular function"	"Pf00400"	"55100"	"ENSG00000082068"	"WDR70"	"hsa:55100; Q9H053; Q9NW82"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"79.3"	"52.2"	"86.9"	"83.6"	"91.5"	"67.9"	"95.1"	"130.9"	"142.4"	"255.8"	"317.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P53041"	"Serine/threonine-protein phosphatase 5 OS=Homo sapiens OX=9606 GN=PPP5C PE=1 SV=1"	"0.000"	""	"8"	"4"	"7"	"4"	"499"	"56.8"	"6.28"	"961.57"	"13.38"	"3"	"4"	"cell cycle OR cell proliferation;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00149, Pf00515, Pf08321"	"5536"	"ENSG00000011485"	"PPP5C"	"hsa:5536; P53041; Q16722; Q53XV2"	"MAPK signaling pathway; ATM signaling in development and disease"	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Negative regulation of MAPK pathway; ESR-mediated signaling"	"5"	"0"	"176.8"	"127.8"	"174.2"	"161.2"	"156.8"	"182.6"	"231.9"	"848.8"	"975.5"	"2731.9"	"4087.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09417"	"Dihydropteridine reductase OS=Homo sapiens OX=9606 GN=QDPR PE=1 SV=2"	"0.000"	""	"18"	"3"	"6"	"3"	"244"	"25.8"	"7.37"	"1303.85"	"13.38"	"3"	"3"	"other metabolic processes;developmental processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00106"	"5860"	"ENSG00000151552"	"QDPR"	"A8K158; B3KW71; hsa:5860; P09417; Q53F52; Q9H3M5"	""	"Phenylalanine metabolism"	"1"	"0"	"50.4"	"24.8"	"53.5"	"46.4"	"39.6"	"41.4"	"75.1"	"139.6"	"156.6"	"526.5"	"846.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95071"	"E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2"	"0.000"	""	"4"	"9"	"10"	"9"	"2799"	"309.2"	"5.85"	"1398.00"	"13.36"	"5"	"5"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00632, Pf00658, Pf11547"	"51366"	"ENSG00000104517"	"UBR5"	"B2RP24; hsa:51366; J3KMW7; O94970; O95071; Q9NPL3"	"Mesodermal commitment pathway"	""	"1"	"0"	"685.9"	"534.1"	"611.5"	"611.5"	"564.2"	"620.8"	"769.7"	"949.2"	"867.7"	"1389.1"	"1754.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VT52"	"Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1"	"0.000"	""	"4"	"4"	"7"	"4"	"1461"	"155.9"	"7.42"	"1050.49"	"13.28"	"3"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf04818"	"23248"	"ENSG00000163125"	"RPRD2"	"A8K6N8; B3KPT1; B4E2Q6; hsa:23248; O75048; Q5VT51; Q5VT52; Q5VT53; Q6MZL4; Q86XD2; Q9P0D7"	""	"RNA polymerase II transcribes snRNA genes"	"1"	"0"	"251.4"	"176.2"	"234.7"	"200.4"	"186.7"	"198.5"	"251.3"	"412.0"	"405.4"	"871.5"	"1225.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19525"	"Interferon-induced, double-stranded RNA-activated protein kinase OS=Homo sapiens OX=9606 GN=EIF2AK2 PE=1 SV=2"	"0.000"	""	"11"	"5"	"8"	"5"	"551"	"62.1"	"8.40"	"1432.51"	"13.25"	"4"	"4"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;kinase activity;other molecular function"	"Pf00035, Pf00069"	"5610"	"ENSG00000055332"	"EIF2AK2"	"A8K3P0; D6W584; E9PC80; hsa:5610; P19525; Q52M43; Q7Z6F6; Q9UIR4"	"Translation factors; Alzheimer's disease and miRNA effects; Ebola virus infection in host; Measles virus infection; Type I interferon induction and signaling during SARS-CoV-2 infection; Host-pathogen interaction of human coronaviruses - interferon induction; Alzheimer's disease; Roles of ceramides in development of insulin resistance; Type II interferon signaling"	"ISG15 antiviral mechanism; Interferon alpha/beta signaling; Inhibition of PKR"	"12"	"0"	"201.0"	"149.2"	"210.0"	"179.9"	"169.4"	"200.7"	"235.7"	"417.4"	"443.3"	"928.2"	"1289.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13620"	"Cullin-4B OS=Homo sapiens OX=9606 GN=CUL4B PE=1 SV=4"	"0.000"	""	"4"	"4"	"7"	"2"	"913"	"103.9"	"7.37"	"1252.38"	"13.25"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00888, Pf10557"	"8450"	"ENSG00000158290"	"CUL4B"	"B1APK5; B3KVX4; B7Z5K8; hsa:8450; Q13620; Q6PIE4; Q6UP07; Q7Z673; Q9BY37; Q9UEB7; Q9UED7"	"Mesodermal commitment pathway; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"Neddylation; Formation of Incision Complex in GG-NER; DNA Damage Recognition in GG-NER; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Recognition of DNA damage by PCNA-containing replication complex; Dual Incision in GG-NER"	"13"	"2"	"121.1"	"70.1"	"128.5"	"116.9"	"116.3"	"119.0"	"145.8"	"502.0"	"601.1"	"1900.3"	"2820.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96SK2"	"Transmembrane protein 209 OS=Homo sapiens OX=9606 GN=TMEM209 PE=1 SV=2"	"0.000"	""	"8"	"2"	"4"	"2"	"561"	"62.9"	"8.63"	"358.61"	"13.24"	"1"	"2"	""	"other membranes"	""	"Pf09786"	"84928"	"ENSG00000146842"	"TMEM209"	"A4D1L1; hsa:84928; Q49A50; Q6PF00; Q8NCH3; Q96SK2; Q96SL6"	""	""	"0"	"0"	"38.4"	"34.8"	"31.5"	"41.1"	"32.4"	"34.2"	"45.6"	"83.6"	"75.4"	"148.2"	"197.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96MU7"	"YTH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=YTHDC1 PE=1 SV=3"	"0.000"	""	"9"	"4"	"6"	"4"	"727"	"84.6"	"6.23"	"707.62"	"13.22"	"2"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;nucleus"	"nucleic acid binding activity"	"Pf04146"	"91746"	"ENSG00000083896; ENSG00000275272"	"YTHDC1"	"hsa:91746; Q4W5Q3; Q7Z622; Q8TF35; Q96MU7"	""	""	"0"	"0"	"216.8"	"222.9"	"183.5"	"176.7"	"171.7"	"175.7"	"216.3"	"367.5"	"355.5"	"663.7"	"839.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EK6"	"Glucosamine 6-phosphate N-acetyltransferase OS=Homo sapiens OX=9606 GN=GNPNAT1 PE=1 SV=1"	"0.000"	""	"22"	"3"	"6"	"3"	"184"	"20.7"	"7.99"	"1298.63"	"13.19"	"3"	"3"	"other metabolic processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle"	"other molecular function"	"Pf00583"	"64841"	"ENSG00000100522"	"GNPNAT1"	"hsa:64841; Q96EK6"	""	"Synthesis of UDP-N-acetyl-glucosamine"	"1"	"0"	"161.8"	"139.2"	"170.7"	"155.3"	"162.9"	"153.3"	"187.5"	"237.8"	"226.3"	"583.4"	"1057.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKL0"	"REST corepressor 1 OS=Homo sapiens OX=9606 GN=RCOR1 PE=1 SV=2"	"0.000"	""	"7"	"3"	"6"	"3"	"485"	"53.3"	"7.03"	"1280.73"	"13.17"	"3"	"3"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00249, Pf01448"	"23186"	"ENSG00000089902"	"RCOR1"	"hsa:23186; J3KN32; Q15044; Q6P2I9; Q86VG5; Q9UKL0"	""	"Regulation of PTEN gene transcription; Factors involved in megakaryocyte development and platelet production; Potential therapeutics for SARS; HDACs deacetylate histones"	"4"	"0"	"215.8"	"154.8"	"179.8"	"175.3"	"153.3"	"164.3"	"216.8"	"422.2"	"430.3"	"1206.9"	"2068.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O96000"	"NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 OS=Homo sapiens OX=9606 GN=NDUFB10 PE=1 SV=3"	"0.000"	""	"23"	"4"	"7"	"4"	"172"	"20.8"	"8.48"	"989.80"	"13.16"	"3"	"4"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf10249"	"4716"	"ENSG00000140990"	"NDUFB10"	"hsa:4716; O96000; Q96II6"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Modulators of TCR signaling and T cell activation; Oxidative phosphorylation"	"Complex I biogenesis"	"6"	"0"	"127.3"	"95.3"	"119.9"	"92.6"	"110.0"	"123.5"	"143.3"	"311.6"	"352.7"	"782.5"	"982.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5J9"	"Mitochondrial import inner membrane translocase subunit Tim8 B OS=Homo sapiens OX=9606 GN=TIMM8B PE=1 SV=1"	"0.000"	""	"45"	"4"	"7"	"4"	"83"	"9.3"	"5.12"	"1020.46"	"13.13"	"3"	"4"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf02953"	"26521"	"ENSG00000150779"	"TIMM8B"	"B0YJA5; hsa:26521; Q3KQS9; Q9UN04; Q9Y5J9"	""	"Mitochondrial protein import"	"1"	"0"	"237.8"	"178.4"	"252.0"	"229.3"	"244.1"	"259.3"	"300.6"	"592.4"	"584.9"	"1859.8"	"2891.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NV70"	"Exocyst complex component 1 OS=Homo sapiens OX=9606 GN=EXOC1 PE=1 SV=4"	"0.000"	""	"5"	"3"	"5"	"3"	"894"	"101.9"	"6.61"	"1052.56"	"13.12"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf09763, Pf15277"	"55763"	"ENSG00000090989"	"EXOC1"	"hsa:55763; Q504V4; Q8WUE7; Q96T15; Q9NV70; Q9NZE4"	"Ciliary landscape"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"4"	"0"	"17.0"	"16.2"	"16.5"	"18.9"	"18.0"	"39.6"	"61.6"	"195.7"	"210.3"	"425.6"	"409.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6NSI4"	"RPA-related protein RADX OS=Homo sapiens OX=9606 GN=RADX PE=1 SV=2"	"0.000"	""	"5"	"3"	"6"	"3"	"855"	"97.5"	"8.41"	"1252.65"	"13.09"	"2"	"3"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf17659"	"55086"	"ENSG00000147231"	"RADX"	"H7BY89; hsa:55086; Q4G0L7; Q5JQS1; Q5JRF9; Q6NSI4; Q6PHY5; Q6PII9; Q6PJU8; Q9H7W5; Q9NWA6"	""	""	"0"	"0"	"84.7"	"89.6"	"90.7"	"85.9"	"95.5"	"106.9"	"125.2"	"268.3"	"264.8"	"647.5"	"897.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22392"	"Nucleoside diphosphate kinase B OS=Homo sapiens OX=9606 GN=NME2 PE=1 SV=1"	"0.000"	""	"24"	"3"	"6"	"2"	"152"	"17.3"	"8.41"	"1368.49"	"13.06"	"3"	"3"	"cell adhesion;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00334"	"4831; 654364"	"ENSG00000243678"	"NME2"	"A8MWA3; hsa:4831; hsa:654364; P22392; Q1WM23; Q6LCT6"	"Pyrimidine metabolism"	"Neutrophil degranulation; Azathioprine ADME; Interconversion of nucleotide di- and triphosphates; Ribavirin ADME"	"5"	"1"	"390.6"	"310.3"	"428.1"	"367.0"	"321.9"	"307.6"	"414.1"	"758.6"	"643.2"	"1320.9"	"2559.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P31483"	"Nucleolysin TIA-1 isoform p40 OS=Homo sapiens OX=9606 GN=TIA1 PE=1 SV=3"	"0.000"	""	"8"	"4"	"8"	"1"	"386"	"42.9"	"7.74"	"1265.01"	"13.04"	"4"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"7072"	"ENSG00000116001"	"TIA1"	"hsa:7072; P31483; Q53SS9; Q96B58"	""	"FGFR2 alternative splicing"	"1"	"0"	"297.0"	"287.5"	"251.7"	"255.0"	"257.5"	"261.8"	"327.9"	"360.9"	"326.3"	"457.2"	"497.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75821"	"Eukaryotic translation initiation factor 3 subunit G OS=Homo sapiens OX=9606 GN=EIF3G PE=1 SV=2"	"0.000"	""	"14"	"3"	"5"	"3"	"320"	"35.6"	"6.13"	"763.98"	"13.03"	"2"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf12353"	"8666"	"ENSG00000130811"	"EIF3G"	"hsa:8666; O14801; O75821; Q969U5"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"8"	"0"	"144.6"	"118.0"	"161.5"	"150.5"	"135.0"	"139.2"	"182.8"	"291.0"	"285.5"	"677.0"	"1494.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9ULR0"	"Pre-mRNA-splicing factor ISY1 homolog OS=Homo sapiens OX=9606 GN=ISY1 PE=1 SV=3"	"0.000"	""	"16"	"4"	"9"	"4"	"285"	"33.0"	"5.17"	"1592.53"	"13.01"	"4"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf06246"	"100534599; 57461"	"ENSG00000240682"	"ISY1"	"hsa:100534599; hsa:57461; Q96IL2; Q9BT05; Q9ULR0"	""	"mRNA Splicing - Major Pathway; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	"5"	"0"	"217.0"	"183.7"	"237.4"	"194.4"	"220.0"	"217.0"	"260.4"	"362.8"	"340.3"	"873.0"	"1559.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15511"	"Actin-related protein 2/3 complex subunit 5 OS=Homo sapiens OX=9606 GN=ARPC5 PE=1 SV=3"	"0.000"	""	"21"	"3"	"8"	"3"	"151"	"16.3"	"5.67"	"1538.65"	"13.01"	"3"	"2"	"cell organization and biogenesis;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf04699"	"10092"	"ENSG00000162704"	"ARPC5"	"A6NEC4; hsa:10092; O15511; Q6PG42"	"Pathogenic Escherichia coli infection; Regulation of actin cytoskeleton"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Neutrophil degranulation; Clathrin-mediated endocytosis; EPHB-mediated forward signaling"	"8"	"0"	"154.5"	"122.9"	"130.9"	"123.3"	"131.5"	"135.1"	"174.9"	"621.3"	"659.8"	"1497.4"	"1929.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75909"	"Cyclin-K OS=Homo sapiens OX=9606 GN=CCNK PE=1 SV=2"	"0.000"	""	"6"	"2"	"6"	"2"	"580"	"64.2"	"8.41"	"1370.02"	"13.01"	"2"	"2"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00134"	"8812"	"ENSG00000090061"	"CCNK"	"hsa:8812; O75909; Q59FT6; Q86U16; Q96B63; Q9NNY9"	"Male infertility"	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes"	"10"	"0"	"30.1"	"29.7"	"38.2"	"36.4"	"36.8"	"37.9"	"42.8"	"102.5"	"114.5"	"294.6"	"404.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HCD5"	"Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2"	"0.000"	""	"11"	"5"	"8"	"5"	"579"	"65.5"	"9.60"	"1320.61"	"13.00"	"4"	"4"	"signal transduction;other biological processes"	"cytoskeleton;nucleus"	"other molecular function"	""	"57727"	"ENSG00000124160"	"NCOA5"	"B2RTV9; E1P5R0; hsa:57727; Q6HA99; Q9H1F2; Q9H2T2; Q9H4Y9; Q9HCD5"	""	""	"0"	"0"	"231.3"	"169.1"	"264.8"	"222.8"	"219.2"	"232.0"	"269.6"	"363.2"	"352.6"	"649.1"	"801.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35658"	"Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2"	"0.000"	""	"2"	"4"	"7"	"3"	"2090"	"213.5"	"7.47"	"1151.43"	"12.98"	"3"	"4"	"cell cycle OR cell proliferation;other metabolic processes;transport;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf18617"	"8021"	"ENSG00000126883"	"NUP214"	"A6NFQ0; hsa:8021; P35658; Q15010; Q3KQZ0; Q5JUP7; Q75R47; Q86XD3"	""	"Rev-mediated nuclear export of HIV RNA; Nuclear import of Rev protein; HCMV Late Events; HCMV Early Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; HuR (ELAVL1) binds and stabilizes mRNA"	"29"	"0"	"400.9"	"297.9"	"345.8"	"337.3"	"323.8"	"360.4"	"433.2"	"623.1"	"610.2"	"1305.3"	"1879.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50502"	"Hsc70-interacting protein OS=Homo sapiens OX=9606 GN=ST13 PE=1 SV=2"	"0.000"	""	"13"	"6"	"10"	"6"	"369"	"41.3"	"5.27"	"2443.71"	"12.95"	"6"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf17830, Pf18253"	"6767"	"ENSG00000100380"	"ST13"	"hsa:6767; O14999; P50502; Q2TU77"	""	"Regulation of HSF1-mediated heat shock response"	"1"	"0"	"849.8"	"691.5"	"1017.4"	"923.1"	"868.8"	"806.8"	"1112.8"	"1838.7"	"1612.9"	"2632.6"	"3386.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51003"	"Poly(A) polymerase alpha OS=Homo sapiens OX=9606 GN=PAPOLA PE=1 SV=4"	"0.000"	""	"8"	"4"	"7"	"3"	"745"	"82.8"	"7.37"	"950.47"	"12.95"	"3"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01909, Pf04926, Pf04928"	"10914"	"ENSG00000090060"	"PAPOLA"	"hsa:10914; P51003; Q86SX4; Q86TV0; Q8IYF5; Q9BVU2"	"mRNA processing"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"5"	"1"	"38.6"	"29.7"	"61.1"	"47.8"	"49.0"	"42.9"	"57.2"	"175.8"	"222.5"	"666.9"	"827.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9ULP9"	"TBC1 domain family member 24 OS=Homo sapiens OX=9606 GN=TBC1D24 PE=1 SV=2"	"0.000"	""	"6"	"3"	"6"	"3"	"559"	"62.9"	"7.36"	"1338.41"	"12.94"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;other cell component"	"enzyme regulator activity"	"Pf00566, Pf07534"	"57465"	"ENSG00000162065"	"TBC1D24"	"A0JNW3; B9A6M6; hsa:57465; Q2KJ08; Q9ULP9"	""	"TBC/RABGAPs"	"1"	"0"	"67.2"	"50.7"	"77.4"	"61.7"	"70.0"	"100.3"	"186.0"	"615.2"	"643.4"	"973.5"	"1118.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46782"	"40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4"	"0.000"	""	"31"	"5"	"9"	"5"	"204"	"22.9"	"9.72"	"1837.75"	"12.94"	"5"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00177"	"6193"	"ENSG00000083845"	"RPS5"	"B2R4T2; hsa:6193; P46782; Q96BN0"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Peptide chain elongation; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"419.0"	"396.8"	"388.4"	"358.8"	"354.1"	"368.1"	"536.3"	"731.7"	"746.5"	"1116.8"	"1469.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99575"	"Ribonucleases P/MRP protein subunit POP1 OS=Homo sapiens OX=9606 GN=POP1 PE=1 SV=2"	"0.000"	""	"4"	"3"	"5"	"3"	"1024"	"114.6"	"9.22"	"269.98"	"12.90"	"1"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06978, Pf08170"	"10940"	"ENSG00000104356"	"POP1"	"A8K5W9; hsa:10940; Q15037; Q99575"	""	"tRNA processing in the nucleus"	"1"	"0"	"317.0"	"69.9"	"546.9"	"398.0"	"378.0"	"391.3"	"490.9"	"453.0"	"459.2"	"557.4"	"681.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5QJE6"	"Deoxynucleotidyltransferase terminal-interacting protein 2 OS=Homo sapiens OX=9606 GN=DNTTIP2 PE=1 SV=2"	"0.000"	""	"5"	"3"	"6"	"3"	"756"	"84.4"	"6.16"	"1207.37"	"12.89"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf08698"	"30836"	"ENSG00000067334"	"DNTTIP2"	"hsa:30836; Q12987; Q53H59; Q5QJE6; Q5TFJ4; Q6TLI0; Q76MJ8; Q86WX9"	""	""	"0"	"0"	"178.2"	"150.4"	"172.1"	"176.1"	"163.2"	"161.7"	"204.0"	"328.5"	"333.9"	"704.7"	"988.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14818"	"Proteasome subunit alpha type-7 OS=Homo sapiens OX=9606 GN=PSMA7 PE=1 SV=1"	"0.000"	""	"15"	"4"	"8"	"4"	"248"	"27.9"	"8.46"	"1449.46"	"12.86"	"4"	"4"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00227, Pf10584"	"5688"	"ENSG00000101182"	"PSMA7"	"B2R515; hsa:5688; O14818; Q5JXJ2; Q9BR53; Q9H4K5; Q9UEU8"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"62"	"0"	"238.0"	"215.8"	"270.3"	"264.7"	"215.8"	"241.6"	"317.6"	"656.7"	"648.4"	"1445.1"	"2605.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UPT8"	"Zinc finger CCCH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=ZC3H4 PE=1 SV=3"	"0.000"	""	"5"	"4"	"7"	"4"	"1303"	"140.2"	"6.27"	"1136.81"	"12.86"	"3"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00642, Pf14608, Pf18044"	"23211"	"ENSG00000130749"	"ZC3H4"	"hsa:23211; Q9UPT8; Q9Y420"	""	""	"0"	"0"	"226.9"	"210.4"	"231.6"	"224.6"	"216.5"	"235.7"	"272.2"	"412.7"	"391.2"	"703.3"	"995.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H993"	"Damage-control phosphatase ARMT1 OS=Homo sapiens OX=9606 GN=ARMT1 PE=1 SV=1"	"0.000"	""	"10"	"3"	"4"	"3"	"441"	"51.1"	"5.76"	"603.91"	"12.84"	"1"	"3"	"other metabolic processes;stress response"	""	"other molecular function"	"Pf01937"	"79624"	"ENSG00000146476"	"ARMT1"	"hsa:79624; Q96FC6; Q9H993; Q9UFY5"	""	""	"0"	"0"	"46.5"	"33.2"	"55.9"	"50.2"	"44.5"	"59.2"	"77.5"	"206.9"	"253.0"	"760.6"	"1516.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BZK7"	"F-box-like/WD repeat-containing protein TBL1XR1 OS=Homo sapiens OX=9606 GN=TBL1XR1 PE=1 SV=1"	"0.000"	""	"8"	"3"	"5"	"3"	"514"	"55.6"	"5.55"	"1184.04"	"12.83"	"2"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400, Pf08513"	"79718"	"ENSG00000177565"	"TBL1XR1"	"D3DNQ9; hsa:79718; Q14DC3; Q9BZK7; Q9H2I1; Q9H9A1"	"Rett syndrome causing genes"	"Heme signaling; Transcriptional activation of mitochondrial biogenesis; HCMV Early Events; HDACs deacetylate histones; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; NOTCH1 Intracellular Domain Regulates Transcription; PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; BMAL1:CLOCK,NPAS2 activates circadian gene expression; Cytoprotection by HMOX1; Activation of gene expression by SREBF (SREBP); Notch-HLH transcription pathway; Loss of MECP2 binding ability to the NCoR/SMRT complex; Regulation of MECP2 expression and activity; NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux; RORA activates gene expression"	"20"	"0"	"647.6"	"269.3"	"1066.9"	"903.8"	"920.4"	"853.0"	"1131.9"	"1179.6"	"1135.0"	"1524.3"	"1510.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13136"	"Liprin-alpha-1 OS=Homo sapiens OX=9606 GN=PPFIA1 PE=1 SV=1"	"0.000"	""	"7"	"7"	"11"	"6"	"1202"	"135.7"	"6.29"	"2712.45"	"12.80"	"7"	"4"	"cell adhesion;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;other cell component"	""	"Pf00536, Pf07647"	"8500"	"ENSG00000131626"	"PPFIA1"	"A6NLE3; hsa:8500; Q13135; Q13136; Q14567; Q8N4I2"	""	"Glutamate Neurotransmitter Release Cycle; Serotonin Neurotransmitter Release Cycle; Norepinephrine Neurotransmitter Release Cycle; Dopamine Neurotransmitter Release Cycle; Acetylcholine Neurotransmitter Release Cycle; Receptor-type tyrosine-protein phosphatases"	"6"	"0"	"195.0"	"169.6"	"164.1"	"161.6"	"157.8"	"168.1"	"205.2"	"272.8"	"259.8"	"446.1"	"698.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WVV9"	"Heterogeneous nuclear ribonucleoprotein L-like OS=Homo sapiens OX=9606 GN=HNRNPLL PE=1 SV=1"	"0.000"	""	"6"	"3"	"8"	"2"	"542"	"60.0"	"7.72"	"1209.31"	"12.77"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf11835, Pf13893"	"92906"	"ENSG00000143889"	"HNRNPLL"	"hsa:92906; Q53T80; Q5JB51; Q5JB52; Q659B9; Q8IVH5; Q8IVH6; Q8WVV9; Q96HR5"	""	""	"0"	"0"	"43.5"	"37.3"	"62.2"	"40.8"	"47.5"	"41.7"	"65.8"	"129.8"	"138.4"	"389.7"	"623.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92621"	"Nuclear pore complex protein Nup205 OS=Homo sapiens OX=9606 GN=NUP205 PE=1 SV=3"	"0.000"	""	"2"	"4"	"6"	"4"	"2012"	"227.8"	"6.19"	"1037.99"	"12.75"	"3"	"3"	"cell organization and biogenesis;transport"	"other membranes;cytosol;nucleus"	"other molecular function"	"Pf11894"	"23165"	"ENSG00000155561"	"NUP205"	"A6H8X3; hsa:23165; Q86YC1; Q92621"	""	"Rev-mediated nuclear export of HIV RNA; Nuclear import of Rev protein; Postmitotic nuclear pore complex (NPC) reformation; HCMV Late Events; HCMV Early Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"29"	"0"	"77.4"	"60.4"	"87.4"	"87.3"	"75.6"	"55.4"	"86.4"	"209.1"	"248.6"	"606.7"	"855.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y224"	"RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1"	"0.000"	""	"23"	"4"	"7"	"4"	"244"	"28.1"	"6.65"	"1706.80"	"12.69"	"4"	"3"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf10036"	"51637"	"ENSG00000087302"	"RTRAF"	"hsa:51637; Q9Y224"	""	"tRNA processing in the nucleus"	"1"	"0"	"246.0"	"205.2"	"192.9"	"180.5"	"199.2"	"196.4"	"262.2"	"368.1"	"359.9"	"726.9"	"949.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5JSZ5"	"Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2"	"0.000"	""	"2"	"3"	"5"	"3"	"2229"	"242.8"	"8.34"	"810.15"	"12.69"	"2"	"3"	"other biological processes"	""	""	"Pf07001"	"84726"	"ENSG00000288701"	"PRRC2B"	"hsa:84726; O60270; Q5JSZ5; Q5JSZ7; Q66VZ2; Q68CR0; Q96EI9; Q9H683"	""	""	"0"	"0"	"150.0"	"158.3"	"128.5"	"147.1"	"118.0"	"136.0"	"164.4"	"207.1"	"203.4"	"305.5"	"388.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TDP1"	"Ribonuclease H2 subunit C OS=Homo sapiens OX=9606 GN=RNASEH2C PE=1 SV=1"	"0.000"	""	"28"	"3"	"4"	"3"	"164"	"17.8"	"5.03"	"382.11"	"12.65"	"1"	"3"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response"	"nucleus;other cell component"	""	"Pf08615"	"84153"	"ENSG00000172922"	"RNASEH2C"	"hsa:84153; Q8TDP1; Q9H7F5"	""	""	"0"	"0"	"99.4"	"68.9"	"106.4"	"96.9"	"94.6"	"92.9"	"118.5"	"487.0"	"487.2"	"1163.4"	"1372.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19367"	"Hexokinase-1 OS=Homo sapiens OX=9606 GN=HK1 PE=1 SV=3"	"0.000"	""	"7"	"5"	"9"	"4"	"917"	"102.4"	"6.80"	"2147.12"	"12.65"	"5"	"4"	"other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;mitochondrion"	"kinase activity;other molecular function"	"Pf00349, Pf03727"	"3098"	"ENSG00000156515"	"HK1"	"E9PCK0; hsa:3098; O43443; O43444; O75574; P19367; Q5VTC3; Q96HC8; Q9NNZ4; Q9NNZ5"	"Cori cycle; Photodynamic therapy-induced HIF-1 survival signaling; Clear cell renal cell carcinoma pathways; Aerobic glycolysis; Disorders of fructose metabolism; Glucose metabolism in triple-negative breast cancer cells; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders; UDP-derived sugars synthesis in fibroblasts; Glucuronidation"	"Glycolysis; Defective HK1 causes hexokinase deficiency (HK deficiency)"	"12"	"0"	"132.6"	"93.0"	"166.1"	"145.7"	"121.2"	"126.4"	"163.6"	"379.5"	"405.9"	"1310.1"	"1666.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62495"	"Eukaryotic peptide chain release factor subunit 1 OS=Homo sapiens OX=9606 GN=ETF1 PE=1 SV=3"	"0.000"	""	"11"	"5"	"9"	"5"	"437"	"49.0"	"5.71"	"1918.18"	"12.63"	"5"	"4"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"enzyme regulator activity;translation activity;nucleic acid binding activity;other molecular function"	"Pf03463, Pf03464, Pf03465"	"2107"	"ENSG00000120705"	"ETF1"	"B2R6B4; D3DQC1; hsa:2107; P46055; P62495; Q5M7Z7; Q96CG1"	"Translation factors"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"5"	"0"	"184.3"	"119.7"	"186.1"	"175.4"	"165.2"	"173.8"	"231.9"	"750.9"	"786.1"	"1811.1"	"1914.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35269"	"General transcription factor IIF subunit 1 OS=Homo sapiens OX=9606 GN=GTF2F1 PE=1 SV=2"	"0.000"	""	"10"	"4"	"8"	"4"	"517"	"58.2"	"7.49"	"2260.15"	"12.62"	"4"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf05793"	"2962"	"ENSG00000125651"	"GTF2F1"	"B2RCS0; hsa:2962; P35269; Q9BWN0"	""	"Viral Messenger RNA Synthesis; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; mRNA Splicing - Major Pathway; Estrogen-dependent gene expression; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM"	"32"	"0"	"177.4"	"134.1"	"149.2"	"165.3"	"159.6"	"189.0"	"211.7"	"355.3"	"335.9"	"704.0"	"1076.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P21127"	"Cyclin-dependent kinase 11B OS=Homo sapiens OX=9606 GN=CDK11B PE=1 SV=4"	"0.000"	""	"7"	"4"	"6"	"4"	"795"	"92.6"	"5.54"	"1286.11"	"12.61"	"3"	"3"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"984"	"ENSG00000248333"	"CDK11B"	"B7ZVY7; hsa:984; J3KTL7; J3QR29; J3QR44; O95265; P21127; Q12817; Q12818; Q12819; Q12820; Q12822; Q8N530; Q9NZS5; Q9UBJ0; Q9UBQ1; Q9UBR0; Q9UNY2; Q9UP57; Q9UP58; Q9UP59"	"1p36 copy number variation syndrome"	"Recruitment of mitotic centrosome proteins and complexes"	"2"	"0"	"306.8"	"267.4"	"311.5"	"308.3"	"265.8"	"276.0"	"365.1"	"454.5"	"444.8"	"860.2"	"1467.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96GQ7"	"Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2"	"0.000"	""	"7"	"5"	"9"	"5"	"796"	"89.8"	"9.28"	"1823.77"	"12.58"	"5"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271"	"55661"	""	"DDX27"	"A0AVB6; B7ZLY1; hsa:55661; Q5VXM7; Q8WYG4; Q969N7; Q96F57; Q96GQ7; Q96L97; Q9BWY9; Q9BXF0; Q9H990; Q9NWU3; Q9P0C2; Q9UGD6"	""	""	"0"	"0"	"52.6"	"50.8"	"64.9"	"58.4"	"56.8"	"54.4"	"79.8"	"119.6"	"110.7"	"287.4"	"335.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H910"	"Jupiter microtubule associated homolog 2 OS=Homo sapiens OX=9606 GN=JPT2 PE=1 SV=1"	"0.000"	""	"16"	"2"	"6"	"2"	"190"	"20.1"	"9.26"	"1426.75"	"12.57"	"2"	"2"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	""	"Pf17054"	"90861"	"ENSG00000206053"	"JPT2"	"B1AJY2; B4DLH4; hsa:90861; Q6EIC7; Q9H910"	""	""	"0"	"0"	"85.5"	"70.0"	"82.6"	"90.5"	"85.7"	"85.9"	"106.6"	"190.3"	"185.6"	"463.5"	"556.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75940"	"Survival of motor neuron-related-splicing factor 30 OS=Homo sapiens OX=9606 GN=SMNDC1 PE=1 SV=1"	"0.000"	""	"22"	"4"	"7"	"4"	"238"	"26.7"	"7.24"	"1002.20"	"12.56"	"3"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf06003"	"10285"	"ENSG00000119953"	"SMNDC1"	"B2RA27; D3DRB1; hsa:10285; O75940; Q5T3K6"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"377.7"	"298.1"	"332.2"	"341.1"	"345.5"	"344.5"	"406.7"	"587.7"	"553.8"	"800.0"	"775.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UEW8"	"STE20/SPS1-related proline-alanine-rich protein kinase OS=Homo sapiens OX=9606 GN=STK39 PE=1 SV=3"	"0.000"	""	"7"	"3"	"8"	"2"	"545"	"59.4"	"6.29"	"1279.03"	"12.54"	"3"	"3"	"protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf12202"	"27347"	"ENSG00000198648"	"STK39"	"hsa:27347; O14774; Q53S90; Q53SL7; Q53SS1; Q9UER4; Q9UEW8; X5D9C8"	""	""	"0"	"0"	"61.4"	"50.3"	"82.5"	"73.9"	"69.0"	"80.8"	"107.0"	"197.9"	"217.6"	"488.8"	"641.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99549"	"M-phase phosphoprotein 8 OS=Homo sapiens OX=9606 GN=MPHOSPH8 PE=1 SV=2"	"0.000"	""	"3"	"2"	"6"	"2"	"860"	"97.1"	"6.06"	"1712.03"	"12.52"	"2"	"2"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00385, Pf12796"	"54737"	"ENSG00000196199"	"MPHOSPH8"	"B7Z6F9; hsa:54737; Q5JPE5; Q5JTQ0; Q86TK3; Q96MK4; Q99549; Q9BTP1"	""	""	"0"	"0"	"214.8"	"166.0"	"203.8"	"207.7"	"202.8"	"204.5"	"237.7"	"429.8"	"412.6"	"926.1"	"1031.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96GM8"	"Target of EGR1 protein 1 OS=Homo sapiens OX=9606 GN=TOE1 PE=1 SV=1"	"0.000"	""	"10"	"4"	"6"	"4"	"510"	"56.5"	"7.18"	"1014.92"	"12.52"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00642, Pf04857"	"114034"	"ENSG00000132773"	"TOE1"	"B4DEM6; hsa:114034; Q6IA35; Q8IWN5; Q96GM8; Q9H846"	""	""	"0"	"0"	"186.8"	"174.0"	"175.7"	"152.2"	"170.5"	"163.9"	"223.0"	"475.2"	"483.5"	"1222.4"	"1549.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13619"	"Cullin-4A OS=Homo sapiens OX=9606 GN=CUL4A PE=1 SV=3"	"0.000"	""	"5"	"4"	"8"	"2"	"759"	"87.6"	"8.13"	"1420.20"	"12.51"	"4"	"4"	"cell cycle OR cell proliferation;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00888, Pf10557"	"8451"	"ENSG00000139842"	"CUL4A"	"A2A2W2; hsa:8451; O75834; Q13619; Q589T6; Q5TC62; Q6UP08; Q9UP17"	"Hippo-Merlin signaling dysregulation; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"Neddylation; Formation of Incision Complex in GG-NER; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Recognition of DNA damage by PCNA-containing replication complex; DNA Damage Recognition in GG-NER; Dual Incision in GG-NER"	"13"	"0"	"88.2"	"91.4"	"85.3"	"79.4"	"79.3"	"89.8"	"109.0"	"276.1"	"271.7"	"703.3"	"1031.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WVM7"	"Cohesin subunit SA-1 OS=Homo sapiens OX=9606 GN=STAG1 PE=1 SV=3"	"0.000"	""	"4"	"4"	"6"	"1"	"1258"	"144.3"	"5.59"	"564.33"	"12.51"	"2"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf08514"	"10274"	"ENSG00000118007"	"STAG1"	"hsa:10274; O00539; Q6P275; Q8WVM7"	"Cell cycle; Regulation of sister chromatid separation at the metaphase-anaphase transition; 10q22q23 copy number variation"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Meiotic synapsis; Estrogen-dependent gene expression; SUMOylation of DNA damage response and repair proteins; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"10"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15294"	"UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Homo sapiens OX=9606 GN=OGT PE=1 SV=3"	"0.000"	""	"5"	"4"	"7"	"4"	"1046"	"116.9"	"6.70"	"872.65"	"12.51"	"3"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00515, Pf13181, Pf13414, Pf13424, Pf13844"	"8473"	"ENSG00000147162"	"OGT"	"hsa:8473; O15294; Q7Z3K0; Q8WWM8; Q96CC1; Q9UG57"	"Ectoderm differentiation; Ectoderm differentiation; Pleural mesothelioma"	"UCH proteinases; Formation of WDR5-containing histone-modifying complexes; Regulation of necroptotic cell death; HATs acetylate histones"	"8"	"0"	"109.9"	"88.8"	"100.2"	"113.6"	"86.1"	"106.4"	"129.8"	"218.9"	"225.3"	"587.5"	"1020.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30533"	"Alpha-2-macroglobulin receptor-associated protein OS=Homo sapiens OX=9606 GN=LRPAP1 PE=1 SV=1"	"0.000"	""	"13"	"4"	"8"	"4"	"357"	"41.4"	"8.78"	"1296.85"	"12.50"	"3"	"4"	"transport;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf06400, Pf06401"	"4043"	"ENSG00000163956"	"LRPAP1"	"D3DVR9; hsa:4043; P30533; Q2M310; Q53HQ3; Q53HS6"	"Cholesterol metabolism"	""	"1"	"0"	"275.3"	"200.8"	"278.8"	"247.7"	"240.6"	"293.2"	"364.2"	"1486.3"	"1381.1"	"2714.8"	"2246.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05787"	"Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7"	"0.000"	""	"11"	"7"	"11"	"1"	"483"	"53.7"	"5.59"	"1917.10"	"12.48"	"6"	"5"	"cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00038, Pf16208"	"3856"	"ENSG00000170421"	"KRT8"	"A8K4H3; B0AZN5; F8VXB4; hsa:3856; P05787; Q14099; Q14716; Q14717; Q53GJ0; Q6DHW5; Q6GMY0; Q6P4C7; Q96J60"	"Primary focal segmental glomerulosclerosis (FSGS); Acute viral myocarditis"	"Formation of the cornified envelope"	"4"	"0"	"25.9"	"11.1"	"19.9"	"16.7"	"15.7"	"12.4"	"19.6"	"40.0"	"48.1"	"86.3"	"114.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P16403"	"Histone H1.2 OS=Homo sapiens OX=9606 GN=H1-2 PE=1 SV=2"	"0.000"	""	"23"	"6"	"10"	"6"	"213"	"21.4"	"10.93"	"2302.14"	"12.46"	"6"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00538"	"3006"	"ENSG00000187837"	"H1-2"	"A8K4I2; hsa:3006; P16403"	""	"Apoptosis induced DNA fragmentation; Formation of Senescence-Associated Heterochromatin Foci (SAHF)"	"2"	"0"	"707.4"	"559.9"	"693.7"	"566.6"	"574.0"	"630.1"	"878.2"	"1486.3"	"1491.4"	"3210.3"	"5044.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6PD62"	"RNA polymerase-associated protein CTR9 homolog OS=Homo sapiens OX=9606 GN=CTR9 PE=1 SV=1"	"0.000"	""	"3"	"5"	"10"	"5"	"1173"	"133.4"	"6.77"	"2261.83"	"12.45"	"5"	"4"	"cell-cell signaling;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf13181"	"9646"	"ENSG00000198730"	"CTR9"	"D3DQV8; hsa:9646; Q15015; Q6PD62"	"Endoderm differentiation"	"E3 ubiquitin ligases ubiquitinate target proteins; RNA Polymerase II Pre-transcription Events; Formation of RNA Pol II elongation complex"	"5"	"0"	"262.1"	"288.4"	"188.7"	"207.5"	"191.8"	"232.8"	"294.0"	"459.2"	"451.3"	"1004.6"	"1562.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00308"	"NEDD4-like E3 ubiquitin-protein ligase WWP2 OS=Homo sapiens OX=9606 GN=WWP2 PE=1 SV=2"	"0.000"	""	"3"	"2"	"6"	"2"	"870"	"98.9"	"7.12"	"1253.46"	"12.45"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00397, Pf00632"	"11060"	"ENSG00000198373"	"WWP2"	"A6NEP1; B2R706; B4DTL5; F5H213; H3BRF3; hsa:11060; I3RSG8; O00308; Q6ZTQ5; Q96CZ2; Q9BWN6"	""	"RHOQ GTPase cycle; Regulation of PTEN stability and activity; RHOJ GTPase cycle; NOTCH3 Activation and Transmission of Signal to the Nucleus; RHOU GTPase cycle"	"5"	"0"	"15.9"	"12.2"	"32.3"	"23.7"	"24.3"	"23.3"	"28.7"	"48.5"	"52.2"	"120.5"	"167.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3C6"	"Peptidyl-prolyl cis-trans isomerase-like 1 OS=Homo sapiens OX=9606 GN=PPIL1 PE=1 SV=1"	"0.000"	""	"30"	"4"	"8"	"4"	"166"	"18.2"	"7.99"	"1683.11"	"12.43"	"4"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes"	"nucleus"	"other molecular function"	"Pf00160"	"51645"	"ENSG00000137168"	"PPIL1"	"hsa:51645; O15001; Q5TDC9; Q9Y3C6"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"359.5"	"317.3"	"298.8"	"308.7"	"269.7"	"294.9"	"414.3"	"599.1"	"550.6"	"1236.3"	"2143.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WXA9"	"Splicing regulatory glutamine/lysine-rich protein 1 OS=Homo sapiens OX=9606 GN=SREK1 PE=1 SV=1"	"0.000"	""	"7"	"2"	"3"	"2"	"508"	"59.3"	"10.39"	"577.90"	"12.42"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf00076"	"140890"	"ENSG00000153914"	"SREK1"	"A4FTW3; hsa:140890; Q2M1J0; Q86X37; Q8WXA9"	"mRNA processing"	""	"1"	"0"	"93.1"	"64.8"	"103.9"	"79.1"	"75.0"	"90.5"	"117.9"	"199.2"	"277.0"	"647.9"	"976.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13618"	"Cullin-3 OS=Homo sapiens OX=9606 GN=CUL3 PE=1 SV=2"	"0.000"	""	"5"	"4"	"8"	"4"	"768"	"88.9"	"8.48"	"1326.93"	"12.41"	"4"	"4"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00888, Pf10557"	"8452"	"ENSG00000036257"	"CUL3"	"A8K536; B8ZZC3; hsa:8452; O75415; Q13618; Q569L3; Q9UBI8; Q9UET7"	"Hedgehog signaling pathway; NRF2-ARE regulation; 22q11.2 copy number variation syndrome; Head and neck squamous cell carcinoma; 1p36 copy number variation syndrome"	"Hedgehog 'on' state; Potential therapeutics for SARS; Antigen processing: Ubiquitination & Proteasome degradation; Degradation of DVL; Regulation of RAS by GAPs; Neddylation; KEAP1-NFE2L2 pathway; RHOBTB3 ATPase cycle; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle"	"15"	"0"	"150.0"	"107.6"	"173.1"	"156.8"	"142.0"	"165.2"	"211.6"	"630.6"	"681.6"	"1419.0"	"1880.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08754"	"Guanine nucleotide-binding protein G(i) subunit alpha OS=Homo sapiens OX=9606 GN=GNAI3 PE=1 SV=3"	"0.000"	""	"11"	"4"	"7"	"3"	"354"	"40.5"	"5.69"	"918.61"	"12.39"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00503"	"2773"	"ENSG00000065135"	"GNAI3"	"hsa:2773; P08754; P17539; Q5TZX1"	"Thyroid stimulating hormone (TSH) signaling pathway; S1P receptor signal transduction; Complement system; G protein signaling pathways; Chemokine signaling pathway; Hippo signaling regulation pathways; Purinergic signaling; Calcium regulation in cardiac cells; 5q35 copy number variation; Serotonin HTR1 group and FOS pathway"	"G alpha (i) signalling events; G alpha (z) signalling events; Adenylate cyclase inhibitory pathway; ADP signalling through P2Y purinoceptor 12; Extra-nuclear estrogen signaling; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production"	"18"	"0"	"301.6"	"210.7"	"313.6"	"314.7"	"286.4"	"273.9"	"330.5"	"613.0"	"606.1"	"1405.2"	"2121.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25787"	"Proteasome subunit alpha type-2 OS=Homo sapiens OX=9606 GN=PSMA2 PE=1 SV=2"	"0.000"	""	"15"	"2"	"5"	"2"	"234"	"25.9"	"7.43"	"878.88"	"12.37"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	""	"Pf00227, Pf10584"	"5683"	"ENSG00000106588"	"PSMA2"	"hsa:5683; P25787; Q6ICS6; Q9BU45"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Neutrophil degranulation; Antigen processing: Ubiquitination & Proteasome degradation; FCERI mediated NF-kB activation; Downstream TCR signaling; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"63"	"0"	"68.9"	"56.7"	"70.5"	"69.6"	"66.2"	"63.5"	"94.1"	"153.9"	"158.2"	"412.4"	"895.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P17480"	"Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF PE=1 SV=1"	"0.000"	""	"5"	"3"	"6"	"3"	"764"	"89.4"	"5.81"	"1400.23"	"12.31"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00505, Pf09011, Pf14887"	"7343"	"ENSG00000108312"	"UBTF"	"A8K6R8; hsa:7343; P17480"	"Ectoderm differentiation"	"NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; RNA Polymerase I Promoter Opening"	"6"	"0"	"162.1"	"138.0"	"183.5"	"162.5"	"179.7"	"156.6"	"212.0"	"378.6"	"326.9"	"582.4"	"609.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3E1"	"Hepatoma-derived growth factor-related protein 3 OS=Homo sapiens OX=9606 GN=HDGFL3 PE=1 SV=1"	"0.000"	""	"22"	"3"	"5"	"3"	"203"	"22.6"	"7.99"	"801.12"	"12.31"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus"	"signal transduction activity or receptor binding;cytoskeletal activity"	"Pf00855"	"50810"	"ENSG00000166503"	"HDGFL3"	"hsa:50810; Q9Y3E1"	""	""	"0"	"0"	"211.5"	"159.9"	"195.0"	"181.3"	"184.3"	"176.6"	"233.4"	"914.5"	"850.1"	"1920.8"	"1757.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12979"	"Active breakpoint cluster region-related protein OS=Homo sapiens OX=9606 GN=ABR PE=1 SV=2"	"0.000"	""	"7"	"5"	"6"	"5"	"859"	"97.5"	"6.55"	"492.12"	"12.30"	"2"	"4"	"signal transduction;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity"	"Pf00168, Pf00169, Pf00620, Pf00621"	"29"	"ENSG00000159842; ENSG00000276016; ENSG00000278741"	"ABR"	"B3KW89; B7Z6H7; D3DTH3; D3DTH4; F5H3S2; F5H8B3; hsa:29; Q12979; Q13693; Q13694"	""	"RAC1 GTPase cycle; NRAGE signals death through JNK; G alpha (12/13) signalling events; RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOB GTPase cycle"	"9"	"0"	"262.1"	"210.3"	"260.0"	"269.5"	"254.8"	"255.7"	"319.6"	"779.1"	"809.1"	"1868.9"	"2295.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16795"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFA9 PE=1 SV=2"	"0.000"	""	"12"	"3"	"6"	"3"	"377"	"42.5"	"9.80"	"1297.28"	"12.30"	"3"	"3"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf01370"	"4704"	"ENSG00000139180"	"NDUFA9"	"hsa:4704; Q14076; Q16795; Q2NKX0"	"Electron transport chain: OXPHOS system in mitochondria; Ciliary landscape; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"6"	"0"	"48.1"	"33.1"	"50.9"	"40.3"	"38.1"	"49.7"	"61.7"	"140.9"	"144.6"	"326.3"	"366.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60739"	"Eukaryotic translation initiation factor 1b OS=Homo sapiens OX=9606 GN=EIF1B PE=1 SV=2"	"0.000"	""	"24"	"2"	"6"	"1"	"113"	"12.8"	"7.37"	"1248.37"	"12.29"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"translational apparatus"	"translation activity;nucleic acid binding activity"	"Pf01253"	"10289"	"ENSG00000114784"	"EIF1B"	"hsa:10289; O60739; Q9UQF8"	""	""	"0"	"1"	"96.0"	"61.7"	"105.9"	"102.4"	"95.2"	"112.5"	"140.3"	"598.1"	"589.1"	"1096.5"	"1096.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13330"	"Metastasis-associated protein MTA1 OS=Homo sapiens OX=9606 GN=MTA1 PE=1 SV=2"	"0.000"	""	"6"	"4"	"7"	"4"	"715"	"80.7"	"9.26"	"1446.46"	"12.25"	"4"	"3"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00249, Pf00320, Pf01426, Pf01448, Pf17226"	"9112"	"ENSG00000182979"	"MTA1"	"A5PLK4; hsa:9112; Q13330; Q86SW2; Q8NFI8; Q96GI8"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; TAR syndrome"	"Potential therapeutics for SARS; Regulation of PTEN gene transcription; HDACs deacetylate histones; RNA Polymerase I Transcription Initiation; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; SUMOylation of transcription factors"	"8"	"0"	"113.4"	"75.4"	"115.2"	"98.2"	"81.4"	"106.7"	"134.5"	"286.3"	"286.3"	"803.7"	"1171.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H425"	"Uncharacterized protein C1orf198 OS=Homo sapiens OX=9606 GN=C1orf198 PE=1 SV=1"	"0.000"	""	"11"	"3"	"5"	"3"	"327"	"36.3"	"5.72"	"1047.07"	"12.20"	"2"	"3"	""	"cytosol"	""	"Pf15797"	"84886"	"ENSG00000119280"	"C1orf198"	"A8K8R8; B3KTW1; G5EA08; hsa:84886; Q9H425"	""	""	"0"	"0"	"61.4"	"56.6"	"59.5"	"53.6"	"54.1"	"61.8"	"75.7"	"137.7"	"124.3"	"230.6"	"272.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92598"	"Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1"	"0.000"	""	"5"	"4"	"7"	"3"	"858"	"96.8"	"5.39"	"892.04"	"12.14"	"3"	"4"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00012"	"10808"	"ENSG00000120694"	"HSPH1"	"B4DYH1; hsa:10808; O95739; Q5TBM6; Q5TBM7; Q5TBM8; Q92598; Q9UPC4"	""	"Regulation of HSF1-mediated heat shock response; Scavenging by Class F Receptors"	"2"	"0"	"237.9"	"195.6"	"257.5"	"244.1"	"215.5"	"234.3"	"274.0"	"463.0"	"421.4"	"893.2"	"1203.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BTE3"	"Mini-chromosome maintenance complex-binding protein OS=Homo sapiens OX=9606 GN=MCMBP PE=1 SV=2"	"0.000"	""	"9"	"3"	"5"	"3"	"642"	"72.9"	"5.87"	"758.21"	"12.14"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf09739"	"79892"	"ENSG00000197771"	"MCMBP"	"B3KSP7; hsa:79892; Q6IA56; Q9BTE3; Q9BVT9; Q9H916"	""	""	"0"	"0"	"112.0"	"109.8"	"86.7"	"96.9"	"88.8"	"95.0"	"120.5"	"263.0"	"278.1"	"686.6"	"880.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75822"	"Eukaryotic translation initiation factor 3 subunit J OS=Homo sapiens OX=9606 GN=EIF3J PE=1 SV=2"	"0.000"	""	"20"	"3"	"4"	"3"	"258"	"29.0"	"4.83"	"950.77"	"12.13"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf08597"	"8669"	"ENSG00000104131"	"EIF3J"	"B4DUI3; F5H425; hsa:8669; O75822; Q9BUD2; Q9H8Q2; Q9UI65"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"8"	"0"	"63.8"	"41.5"	"69.6"	"60.5"	"55.0"	"65.8"	"81.5"	"386.1"	"363.0"	"2361.7"	"3375.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NQ48"	"Leucine zipper transcription factor-like protein 1 OS=Homo sapiens OX=9606 GN=LZTFL1 PE=1 SV=1"	""	""	"11"	"2"	"3"	"2"	"299"	"34.6"	"5.36"	""	"12.10"	""	"2"	"other biological processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf15294"	"54585"	"ENSG00000163818"	"LZTFL1"	"B3KSI9; B4E0K7; hsa:54585; Q8TC61; Q9NQ48; Q9NQ56"	"Ciliary landscape; Genes related to primary cilium development (based on CRISPR); Ciliopathies; Bardet-Biedl syndrome"	"BBSome-mediated cargo-targeting to cilium"	"5"	"0"	"16.5"	"13.2"	"24.5"	"23.3"	"20.9"	"18.5"	"28.8"	"64.7"	"67.9"	"386.9"	"606.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BTT0"	"Acidic leucine-rich nuclear phosphoprotein 32 family member E OS=Homo sapiens OX=9606 GN=ANP32E PE=1 SV=1"	"0.000"	""	"11"	"2"	"6"	"2"	"268"	"30.7"	"3.85"	"1331.74"	"12.08"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf14580"	"81611"	"ENSG00000143401"	"ANP32E"	"B4E0I6; E9PEA6; hsa:81611; Q5TB18; Q5TB20; Q8N1S4; Q8WWW9; Q9BTT0"	""	""	"0"	"0"	"105.8"	"78.9"	"117.2"	"96.6"	"90.1"	"107.8"	"144.5"	"284.4"	"257.3"	"606.8"	"861.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14320"	"Protein FAM50A OS=Homo sapiens OX=9606 GN=FAM50A PE=1 SV=2"	"0.000"	""	"11"	"4"	"8"	"4"	"339"	"40.2"	"6.83"	"1365.66"	"12.05"	"4"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	"Pf04921"	"9130"	"ENSG00000071859"	"FAM50A"	"A8KAQ4; B2R997; hsa:9130; Q14320; Q5HY37; Q6PJH5"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"226.4"	"185.9"	"211.8"	"200.6"	"210.6"	"210.9"	"259.9"	"783.3"	"774.4"	"1951.5"	"2314.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15287"	"RNA-binding protein with serine-rich domain 1 OS=Homo sapiens OX=9606 GN=RNPS1 PE=1 SV=1"	"0.000"	""	"11"	"3"	"7"	"3"	"305"	"34.2"	"11.84"	"1373.92"	"12.03"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"10921"	"ENSG00000205937"	"RNPS1"	"A8K1P0; B4DDU8; B4DZU7; B7ZA17; hsa:10921; O75308; Q15287; Q32P25; Q8WY42; Q9NYG3"	"mRNA processing"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"7"	"0"	"478.4"	"478.2"	"436.0"	"414.7"	"422.4"	"416.0"	"537.4"	"671.8"	"628.8"	"1225.9"	"1890.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y237"	"Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 OS=Homo sapiens OX=9606 GN=PIN4 PE=1 SV=1"	"0.000"	""	"31"	"4"	"8"	"4"	"131"	"13.8"	"9.77"	"1231.35"	"11.99"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13616"	"5303"	"ENSG00000102309"	"PIN4"	"A8E0G6; B3KXM0; F5H1P5; hsa:5303; Q0D2H3; Q3MHV0; Q52M21; Q5HYW6; Q6IRW4; Q9Y237"	""	""	"0"	"0"	"526.3"	"546.7"	"660.5"	"653.9"	"728.7"	"715.7"	"1094.0"	"1094.5"	"886.3"	"1511.4"	"1784.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NZJ9"	"Diphosphoinositol polyphosphate phosphohydrolase 2 OS=Homo sapiens OX=9606 GN=NUDT4 PE=1 SV=2"	"0.000"	""	"18"	"5"	"8"	"2"	"180"	"20.3"	"6.35"	"1162.35"	"11.98"	"4"	"4"	"other metabolic processes;signal transduction"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00293"	"11163"	"ENSG00000173598"	"NUDT4"	"B7Z916; hsa:11163; Q4AEJ6; Q53EZ2; Q68DD7; Q9NPC5; Q9NS30; Q9NZJ9; Q9NZK0; Q9NZK1"	""	"Synthesis of pyrophosphates in the cytosol"	"1"	"0"	"46.9"	"35.5"	"62.1"	"59.3"	"63.1"	"97.3"	"133.9"	"213.5"	"202.7"	"356.8"	"465.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WUQ7"	"Cactin OS=Homo sapiens OX=9606 GN=CACTIN PE=1 SV=3"	"0.000"	""	"6"	"3"	"6"	"3"	"758"	"88.6"	"9.14"	"1254.61"	"11.98"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf09732, Pf10312"	"58509"	"ENSG00000105298"	"CACTIN"	"A6NNA9; A9UL12; hsa:58509; O75229; Q7LE08; Q8WUQ7; Q9BTA6; Q9Y5A4"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"92.7"	"82.9"	"103.8"	"116.0"	"89.3"	"109.5"	"123.0"	"221.2"	"187.8"	"524.1"	"619.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8N1G0"	"Zinc finger protein 687 OS=Homo sapiens OX=9606 GN=ZNF687 PE=1 SV=1"	""	""	"3"	"2"	"3"	"2"	"1237"	"129.4"	"8.19"	""	"11.96"	""	"2"	""	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00096, Pf16622"	"57592"	"ENSG00000143373"	"ZNF687"	"D3DV17; hsa:57592; Q68DQ8; Q8N1G0; Q9H937; Q9P2A7"	""	""	"0"	"0"	"65.0"	"23.1"	"103.6"	"77.0"	"79.4"	"76.0"	"106.6"	"301.8"	"314.3"	"697.5"	"575.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99733"	"Nucleosome assembly protein 1-like 4 OS=Homo sapiens OX=9606 GN=NAP1L4 PE=1 SV=1"	"0.000"	""	"13"	"5"	"9"	"4"	"375"	"42.8"	"4.69"	"1587.37"	"11.95"	"5"	"4"	"cell organization and biogenesis"	"nucleus;other cell component"	"other molecular function"	"Pf00956"	"4676"	"ENSG00000205531; ENSG00000273562"	"NAP1L4"	"B2R6J4; F5HFY4; hsa:4676; Q99733"	""	""	"0"	"0"	"558.5"	"464.4"	"524.5"	"465.4"	"396.5"	"466.6"	"632.9"	"849.5"	"751.9"	"1563.9"	"2500.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07237"	"Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3"	"0.000"	""	"10"	"3"	"5"	"3"	"508"	"57.1"	"4.87"	"596.75"	"11.93"	"2"	"3"	"protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00085, Pf13848"	"5034"	"ENSG00000185624"	"P4HB"	"B2RDQ2; hsa:5034; P07237; P30037; P32079; Q15205; Q6LDE5"	"VEGFA-VEGFR2 signaling; Type I collagen synthesis in the context of osteogenesis imperfecta"	"Hedgehog ligand biogenesis; Collagen biosynthesis and modifying enzymes; Detoxification of Reactive Oxygen Species; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Insulin processing; Interleukin-12 signaling; Interleukin-23 signaling; Chylomicron assembly; VLDL assembly; LDL remodeling"	"13"	"0"	"172.5"	"124.9"	"182.9"	"154.3"	"140.8"	"148.6"	"205.8"	"280.9"	"269.5"	"452.0"	"578.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15014"	"Mortality factor 4-like protein 2 OS=Homo sapiens OX=9606 GN=MORF4L2 PE=1 SV=1"	"0.000"	""	"10"	"3"	"6"	"3"	"288"	"32.3"	"9.72"	"1120.41"	"11.92"	"3"	"3"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	""	"Pf05712"	"9643"	"ENSG00000123562"	"MORF4L2"	"B3KP92; D3DXA5; hsa:9643; Q15014; Q567V0; Q8J026"	""	"HATs acetylate histones"	"1"	"0"	"184.6"	"151.0"	"180.9"	"179.7"	"183.0"	"175.6"	"223.5"	"293.5"	"282.7"	"513.9"	"601.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N6N3"	"UPF0690 protein C1orf52 OS=Homo sapiens OX=9606 GN=C1orf52 PE=1 SV=1"	"0.000"	""	"24"	"4"	"7"	"4"	"182"	"20.6"	"5.21"	"1637.01"	"11.90"	"4"	"3"	""	"nucleus"	""	"Pf15559"	"148423"	"ENSG00000162642"	"C1orf52"	"B3KX89; hsa:148423; Q8N6N3; Q8TDK5; Q8TDK6"	""	""	"0"	"0"	"609.3"	"539.1"	"572.0"	"581.6"	"546.6"	"489.6"	"635.8"	"781.4"	"746.4"	"1166.1"	"1688.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61964"	"WD repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=WDR5 PE=1 SV=1"	"0.000"	""	"14"	"4"	"7"	"4"	"334"	"36.6"	"8.27"	"1205.43"	"11.86"	"4"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00400"	"11091"	"ENSG00000196363"	"WDR5"	"hsa:11091; P61964; Q91VA5; Q9NWX7; Q9UGP9"	"Pleural mesothelioma; Kleefstra syndrome"	"Activation of anterior HOX genes in hindbrain development during early embryogenesis; PKMTs methylate histone lysines; Neddylation; Formation of WDR5-containing histone-modifying complexes; RMTs methylate histone arginines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; HATs acetylate histones; Cardiogenesis"	"10"	"0"	"69.2"	"62.8"	"81.1"	"85.7"	"72.4"	"84.6"	"104.7"	"221.3"	"243.0"	"709.6"	"1027.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13667"	"Protein disulfide-isomerase A4 OS=Homo sapiens OX=9606 GN=PDIA4 PE=1 SV=2"	"0.000"	""	"9"	"5"	"7"	"4"	"645"	"72.9"	"5.07"	"1265.09"	"11.86"	"4"	"3"	"protein metabolism;other metabolic processes;stress response;transport"	"non-structural extracellular;ER/Golgi;other cell component"	"other molecular function"	"Pf00085, Pf13848"	"9601"	"ENSG00000155660"	"PDIA4"	"A8K4K6; hsa:9601; P13667; Q549T6"	""	""	"0"	"1"	"627.8"	"539.4"	"543.3"	"584.9"	"506.4"	"522.2"	"668.1"	"883.8"	"751.2"	"1077.0"	"1602.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14203"	"Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3"	"0.000"	""	"5"	"4"	"6"	"3"	"1278"	"141.6"	"5.81"	"1327.55"	"11.84"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01302, Pf12455"	"1639"	"ENSG00000204843"	"DCTN1"	"A8MY36; B4DM45; E9PFS5; E9PGE1; G5E9H4; hsa:1639; O95296; Q14203; Q6IQ37; Q9BRM9; Q9UIU1; Q9UIU2"	""	"MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Signaling by ALK fusions and activated point mutants; XBP1(S) activates chaperone genes"	"6"	"0"	"34.7"	"22.5"	"48.6"	"29.1"	"23.5"	"35.6"	"44.3"	"82.1"	"70.0"	"202.5"	"364.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UPT5"	"Exocyst complex component 7 OS=Homo sapiens OX=9606 GN=EXOC7 PE=1 SV=3"	"0.000"	""	"4"	"2"	"6"	"2"	"735"	"83.3"	"6.79"	"1429.78"	"11.83"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf03081"	"23265"	"ENSG00000182473"	"EXOC7"	"B5MC69; B8XXP2; hsa:23265; Q8ND93; Q8WV91; Q96FF0; Q9H8C3; Q9H9X3; Q9HA32; Q9UPT5"	"Angiopoietin-like protein 8 regulatory pathway; Ciliary landscape"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"5"	"0"	"32.8"	"20.7"	"40.3"	"41.1"	"38.9"	"56.9"	"71.4"	"221.1"	"251.7"	"434.2"	"473.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75306"	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2"	"0.000"	""	"7"	"2"	"6"	"2"	"463"	"52.5"	"7.55"	"1162.82"	"11.82"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"other membranes;mitochondrion;nucleus"	"transporter activity;other molecular function"	"Pf00346"	"4720"	"ENSG00000158864"	"NDUFS2"	"D3DVG7; hsa:4720; J3KPM7; O75306; Q5VTW0; Q969P3; Q9UEV3"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"83.2"	"66.3"	"87.4"	"83.4"	"82.4"	"81.7"	"96.4"	"227.5"	"253.4"	"551.7"	"685.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62851"	"40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1"	"0.000"	""	"28"	"4"	"8"	"4"	"125"	"13.7"	"10.11"	"1176.68"	"11.82"	"4"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf03297"	"6230"	"ENSG00000118181; ENSG00000280831"	"RPS25"	"B2R4M7; hsa:6230; P25111; P62851"	"Cytoplasmic ribosomal proteins"	"Major pathway of rRNA processing in the nucleolus and cytosol; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"710.9"	"598.9"	"739.2"	"697.6"	"660.0"	"635.5"	"940.7"	"979.8"	"940.1"	"1344.9"	"1506.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HCS7"	"Pre-mRNA-splicing factor SYF1 OS=Homo sapiens OX=9606 GN=XAB2 PE=1 SV=2"	"0.000"	""	"5"	"3"	"6"	"3"	"855"	"99.9"	"6.23"	"1402.94"	"11.81"	"3"	"3"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes"	"nucleus;other cell component"	""	"Pf13181"	"56949"	"ENSG00000076924"	"XAB2"	"hsa:56949; Q8TET6; Q96HB0; Q96IW0; Q9HCS7; Q9NRG6; Q9ULP3"	"Rett syndrome causing genes; Nucleotide excision repair in xeroderma pigmentosum"	"mRNA Splicing - Major Pathway; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	"7"	"0"	"109.3"	"73.3"	"135.0"	"113.5"	"109.8"	"113.6"	"129.1"	"226.0"	"228.6"	"515.2"	"785.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BYW2"	"Histone-lysine N-methyltransferase SETD2 OS=Homo sapiens OX=9606 GN=SETD2 PE=1 SV=3"	"0.000"	""	"1"	"4"	"9"	"4"	"2564"	"287.4"	"6.14"	"1618.85"	"11.81"	"4"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00397, Pf00856, Pf08236, Pf17907"	"29072"	"ENSG00000181555"	"SETD2"	"hsa:29072; O75397; O75405; Q17RW8; Q5BKS9; Q5QGN2; Q69YI5; Q6IN64; Q6ZN53; Q6ZS25; Q8N3R0; Q8TCN0; Q9BYW2; Q9C0D1; Q9H696; Q9NZW9"	"Histone modifications; Mesodermal commitment pathway; Mesodermal commitment pathway; Pathways affected in adenoid cystic carcinoma; Clear cell renal cell carcinoma pathways; Type 2 papillary renal cell carcinoma; Pleural mesothelioma"	"PKMTs methylate histone lysines"	"8"	"0"	"390.5"	"305.0"	"367.1"	"347.0"	"326.5"	"351.1"	"409.5"	"595.3"	"623.1"	"1121.2"	"1443.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TAD8"	"Smad nuclear-interacting protein 1 OS=Homo sapiens OX=9606 GN=SNIP1 PE=1 SV=1"	"0.000"	""	"10"	"2"	"4"	"2"	"396"	"45.8"	"9.99"	"1277.19"	"11.80"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity"	"Pf00498"	"79753"	"ENSG00000163877"	"SNIP1"	"hsa:79753; Q8TAD8; Q96SP9; Q9H9T7"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"38.6"	"32.6"	"36.2"	"32.6"	"34.1"	"32.9"	"52.1"	"102.9"	"101.3"	"424.6"	"652.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UG63"	"ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2"	"0.000"	""	"7"	"3"	"6"	"3"	"623"	"71.2"	"7.37"	"1071.25"	"11.79"	"3"	"3"	""	""	"other molecular function"	"Pf00005, Pf12848"	"10061; 114483834"	"ENSG00000033050"	"ABCF2"	"hsa:10061; hsa:114483834; O60864; Q75MJ0; Q75MJ1; Q96TE8; Q9UG63"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"79.2"	"76.3"	"98.4"	"104.4"	"90.8"	"91.3"	"90.1"	"143.3"	"116.4"	"158.9"	"155.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00231"	"26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3"	"0.000"	""	"11"	"3"	"4"	"3"	"422"	"47.4"	"6.48"	"416.29"	"11.78"	"1"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf01399, Pf18055, Pf18503"	"5717"	"ENSG00000108671"	"PSMD11"	"A8K3I7; E1P663; hsa:5717; O00231; O00495; Q53FT5"	"Proteasome degradation; Parkin-ubiquitin proteasomal system pathway; VEGFA-VEGFR2 signaling"	"Separation of Sister Chromatids; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"63"	"0"	"66.0"	"63.0"	"86.6"	"79.2"	"65.5"	"63.2"	"84.6"	"189.4"	"182.4"	"624.8"	"1286.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q2NKX8"	"DNA excision repair protein ERCC-6-like OS=Homo sapiens OX=9606 GN=ERCC6L PE=1 SV=1"	"0.000"	""	"3"	"3"	"5"	"3"	"1250"	"141.0"	"5.31"	"1003.43"	"11.74"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271"	"54821"	"ENSG00000186871"	"ERCC6L"	"hsa:54821; Q2NKX8; Q8NCI1; Q96H93; Q9NXQ8"	""	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"6"	"0"	"96.5"	"77.0"	"88.6"	"78.9"	"87.7"	"71.3"	"103.2"	"180.3"	"181.5"	"429.4"	"551.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P18859"	"ATP synthase-coupling factor 6, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PF PE=1 SV=1"	"0.000"	""	"36"	"2"	"3"	"2"	"108"	"12.6"	"9.52"	"329.32"	"11.73"	"1"	"2"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf05511"	"522"	"ENSG00000154723"	"ATP5PF"	"hsa:522; J3KQ83; P18859"	"Electron transport chain: OXPHOS system in mitochondria; Oxidative phosphorylation"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"4"	"0"	"91.7"	"70.8"	"78.9"	"82.6"	"83.3"	"89.2"	"116.5"	"148.5"	"156.7"	"312.5"	"404.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96T88"	"E3 ubiquitin-protein ligase UHRF1 OS=Homo sapiens OX=9606 GN=UHRF1 PE=1 SV=1"	"0.000"	""	"5"	"2"	"6"	"2"	"793"	"89.8"	"7.56"	"1199.69"	"11.70"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00240, Pf00628, Pf02182, Pf12148"	"29128"	"ENSG00000276043"	"UHRF1"	"A0JBR2; A8K024; B2RBA9; hsa:29128; Q2HIX7; Q8J022; Q96T88; Q9H6S6; Q9P115; Q9P1U7"	"Pathways affected in adenoid cystic carcinoma; Pleural mesothelioma"	"DNA methylation"	"3"	"0"	"81.8"	"80.5"	"89.5"	"77.2"	"73.8"	"77.7"	"95.5"	"164.5"	"141.7"	"293.0"	"341.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96B26"	"Exosome complex component RRP43 OS=Homo sapiens OX=9606 GN=EXOSC8 PE=1 SV=1"	""	""	"17"	"2"	"2"	"2"	"276"	"30.0"	"5.30"	""	"11.70"	""	"2"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01138, Pf03725"	"11340"	"ENSG00000120699"	"EXOSC8"	"hsa:11340; O43480; Q5TBA5; Q96B26"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	"6"	"0"	"16.2"	"13.6"	"18.5"	"20.8"	"14.5"	"12.7"	"24.2"	"59.4"	"50.2"	"137.5"	"219.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y2L5"	"Trafficking protein particle complex subunit 8 OS=Homo sapiens OX=9606 GN=TRAPPC8 PE=1 SV=2"	""	""	"4"	"3"	"3"	"3"	"1435"	"160.9"	"6.87"	""	"11.69"	""	"3"	"cell organization and biogenesis;transport"	"cytosol;ER/Golgi;other cell component"	""	"Pf12739"	"22878"	"ENSG00000153339"	"TRAPPC8"	"A0JP15; B3KME5; hsa:22878; Q9H0L2; Q9Y2L5"	""	"RAB GEFs exchange GTP for GDP on RABs"	"1"	"0"	"11.4"	"5.7"	"9.5"	"8.8"	"9.6"	"8.6"	"18.2"	"79.3"	"74.0"	"265.4"	"451.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60568"	"Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 OS=Homo sapiens OX=9606 GN=PLOD3 PE=1 SV=1"	"0.000"	""	"6"	"3"	"6"	"3"	"738"	"84.7"	"6.05"	"1220.13"	"11.68"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"non-structural extracellular;extracellular matrix;other membranes;ER/Golgi"	"other molecular function"	"Pf03171"	"8985"	"ENSG00000106397"	"PLOD3"	"B2R6W6; hsa:8985; O60568; Q540C3"	"VEGFA-VEGFR2 signaling; IL-18 signaling pathway"	"Collagen biosynthesis and modifying enzymes"	"3"	"0"	"64.2"	"43.6"	"72.2"	"60.5"	"61.5"	"65.7"	"74.0"	"123.7"	"147.3"	"300.8"	"449.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBW8"	"COP9 signalosome complex subunit 7a OS=Homo sapiens OX=9606 GN=COPS7A PE=1 SV=1"	"0.000"	""	"15"	"3"	"6"	"3"	"275"	"30.3"	"8.22"	"1268.33"	"11.67"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf01399, Pf18392"	"50813"	"ENSG00000111652"	"COPS7A"	"A8K9A6; hsa:50813; Q9NVX3; Q9UBW8; Q9UJW4"	"Ciliary landscape"	"Cargo recognition for clathrin-mediated endocytosis; Formation of TC-NER Pre-Incision Complex; DNA Damage Recognition in GG-NER; Neddylation"	"5"	"0"	"31.3"	"17.4"	"25.2"	"32.6"	"35.1"	"39.6"	"64.1"	"180.2"	"213.2"	"547.0"	"1006.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BQG0"	"Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2"	"0.000"	""	"7"	"5"	"5"	"5"	"1328"	"148.8"	"9.28"	"423.58"	"11.64"	"1"	"4"	"cell organization and biogenesis;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04931"	"10514"	"ENSG00000132382"	"MYBBP1A"	"hsa:10514; Q86VM3; Q9BQG0; Q9BW49; Q9P0V5; Q9UF99"	"Energy metabolism; 10q11.21q11.23 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression"	"3"	"0"	"80.9"	"73.7"	"233.9"	"97.7"	"96.5"	"81.0"	"93.5"	"134.7"	"138.6"	"162.6"	"224.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UJV9"	"Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2"	"0.000"	""	"9"	"5"	"9"	"5"	"622"	"69.8"	"6.84"	"1495.02"	"11.60"	"5"	"4"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00270, Pf00271"	"51428"	"ENSG00000183258"	"DDX41"	"B2RDC8; hsa:51428; Q96BK6; Q96K05; Q9NT96; Q9NW04; Q9UJV9"	"5q35 copy number variation"	"mRNA Splicing - Major Pathway; Regulation of innate immune responses to cytosolic DNA; IRF3-mediated induction of type I IFN"	"5"	"0"	"71.0"	"41.6"	"85.2"	"74.1"	"75.6"	"75.4"	"87.0"	"199.4"	"204.0"	"598.3"	"881.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52739"	"Zinc finger protein 131 OS=Homo sapiens OX=9606 GN=ZNF131 PE=1 SV=2"	"0.000"	""	"4"	"2"	"6"	"2"	"623"	"71.4"	"5.19"	"1183.22"	"11.58"	"2"	"2"	"other biological processes"	"cytoskeleton;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00651, Pf12874"	"7690"	"ENSG00000172262"	"ZNF131"	"B4DRL3; hsa:7690; P52739; Q6PIF0"	""	"SUMOylation of transcription cofactors"	"1"	"0"	"23.1"	"10.5"	"35.2"	"27.2"	"22.9"	"24.8"	"38.4"	"101.8"	"101.1"	"344.4"	"426.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N6H7"	"ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1"	"0.000"	""	"8"	"4"	"7"	"4"	"521"	"56.7"	"7.99"	"1198.11"	"11.56"	"3"	"4"	"cell organization and biogenesis;transport"	"plasma membrane;other membranes;cytosol;ER/Golgi"	"enzyme regulator activity;other molecular function"	"Pf01412"	"84364"	"ENSG00000149182"	"ARFGAP2"	"B4DX29; B7Z9M7; D3DQQ9; hsa:84364; Q3LIF2; Q8N3I1; Q8N6H7; Q96SX7"	"IL-18 signaling pathway; 5q35 copy number variation"	"COPI-dependent Golgi-to-ER retrograde traffic; CDC42 GTPase cycle; COPI-mediated anterograde transport"	"5"	"0"	"431.0"	"398.4"	"403.9"	"398.5"	"412.5"	"412.2"	"494.8"	"809.9"	"784.6"	"1320.4"	"1537.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q68E01"	"Integrator complex subunit 3 OS=Homo sapiens OX=9606 GN=INTS3 PE=1 SV=1"	""	""	"5"	"2"	"2"	"2"	"1043"	"118.0"	"5.80"	""	"11.55"	""	"2"	"cell cycle OR cell proliferation;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	""	"Pf10189"	"65123"	"ENSG00000143624; ENSG00000262826"	"INTS3"	"A8K1W0; B4DQC8; B4E3U9; D3DV57; hsa:65123; Q4G0E5; Q5VUQ5; Q5VUQ6; Q5VUR0; Q5VUR1; Q68DJ1; Q68E01; Q69YR5; Q6AI57; Q6DKG7; Q6MZQ4; Q6MZZ9; Q8NC46; Q8TB23; Q9H6S9"	""	"RNA polymerase II transcribes snRNA genes"	"1"	"0"	"53.4"	"34.6"	"63.2"	"56.3"	"54.6"	"65.6"	"73.1"	"99.0"	"102.4"	"178.7"	"245.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75534"	"Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2"	"0.000"	""	"4"	"5"	"7"	"5"	"798"	"88.8"	"6.25"	"1079.10"	"11.54"	"3"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"nucleic acid binding activity"	"Pf00313, Pf12901"	"7812"	"ENSG00000009307"	"CSDE1"	"A8K281; E9PGZ0; G5E9Q2; hsa:7812; O75534; O94961; Q5TF04; Q5TF05; Q68DF1; Q68DI9; Q9Y2S4"	""	""	"0"	"0"	"322.5"	"259.8"	"345.4"	"307.6"	"294.4"	"290.7"	"382.0"	"667.3"	"623.1"	"1762.1"	"3251.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35998"	"26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3"	"0.000"	""	"15"	"5"	"9"	"5"	"433"	"48.6"	"5.95"	"1884.51"	"11.51"	"4"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf17862"	"5701"	"ENSG00000161057"	"PSMC2"	"A4D0Q1; B7Z5E2; hsa:5701; P35998; Q3LIA5; Q9UDI3"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"Neutrophil degranulation; ABC-family proteins mediated transport; Defective CFTR causes cystic fibrosis; UCH proteinases; Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; The role of GTSE1 in G2/M progression after G2 checkpoint; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; MAPK6/MAPK4 signaling; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"64"	"0"	"77.7"	"56.6"	"73.8"	"67.4"	"70.2"	"54.2"	"81.3"	"143.6"	"169.0"	"393.8"	"914.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61218"	"DNA-directed RNA polymerases I, II, and III subunit RPABC2 OS=Homo sapiens OX=9606 GN=POLR2F PE=1 SV=1"	"0.000"	""	"32"	"3"	"5"	"3"	"127"	"14.5"	"4.22"	"577.64"	"11.50"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01192"	"5435"	"ENSG00000100142"	"POLR2F"	"hsa:5435; P41584; P61218; Q6IAY3"	"Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"mRNA Splicing - Major Pathway; Transcriptional regulation by small RNAs; B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; RNA Polymerase I Promoter Escape; Inhibition of DNA recombination at telomere; RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; Viral Messenger RNA Synthesis; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Transcription Termination; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM"	"56"	"0"	"368.9"	"333.2"	"355.3"	"336.0"	"356.2"	"380.6"	"569.5"	"842.2"	"800.5"	"1537.9"	"1868.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P53618"	"Coatomer subunit beta OS=Homo sapiens OX=9606 GN=COPB1 PE=1 SV=3"	"0.000"	""	"2"	"1"	"4"	"1"	"953"	"107.1"	"6.05"	"1118.29"	"11.48"	"1"	"1"	"transport"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf01602, Pf07718, Pf14806"	"1315"	"ENSG00000129083"	"COPB1"	"D3DQX0; hsa:1315; P53618; Q6GTT7; Q9NTK2; Q9UNW7"	""	"COPI-dependent Golgi-to-ER retrograde traffic; Neutrophil degranulation; COPI-mediated anterograde transport"	"3"	"0"	"68.8"	"48.2"	"51.9"	"53.5"	"57.5"	"52.5"	"62.0"	"129.3"	"136.4"	"234.6"	"336.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NX55"	"Huntingtin-interacting protein K OS=Homo sapiens OX=9606 GN=HYPK PE=1 SV=2"	"0.000"	""	"33"	"4"	"8"	"4"	"129"	"14.7"	"4.93"	"1923.32"	"11.47"	"4"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf04419, Pf19026"	"100137436; 101127706; 104002286; 104679625; 105491324; 105549422; 105588143; 108521295; 25764; 713266"	"ENSCATG00000038565; ENSGGOG00000014809; ENSMFAG00000057677; ENSMLEG00000000898; ENSMMUG00000022768; ENSMNEG00000018318; ENSPANG00000018102; ENSPPAG00000034659; ENSPTEG00000009792; ENSPTEG00000019135; ENSPTRG00000038721; ENSRBIG00000028237; ENSRROG00000039445; ENSTGEG00000007663"	"HYPK; LOC113219833"	"A0A024R5Q1; A0A1D5R5K3; A0A2I2YQJ1; A0A2J8NTT0; A0A2K5N035; A0A2K5TR12; A0A2K5XAQ0; A0A2K6AXP0; A0A2K6KBN5; A0A2K6QRU2; A0A2R9B6N1; A0A663DGD1; A0A6D2Y1W8; A0A8C9GZF6; A0A8D2ERJ4; A0A8J8XMG0; A9X1C4; F7GC11; G7MX15; G7PB77; H2Q9B3; hsa:25764; mcc:713266; mleu:105549422; mni:105491324; panu:100137436; ptr:104002286; rbb:108521295; rro:104679625"	""	""	"0"	"0"	"45.5"	"39.9"	"53.3"	"57.4"	"41.1"	"56.8"	"73.1"	"399.8"	"389.4"	"1676.6"	"2213.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60645"	"Exocyst complex component 3 OS=Homo sapiens OX=9606 GN=EXOC3 PE=1 SV=3"	"0.000"	""	"3"	"3"	"7"	"3"	"745"	"85.5"	"6.29"	"1556.94"	"11.45"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf06046"	"11336"	"ENSG00000180104"	"EXOC3"	"hsa:11336; O60645; Q6P2E8; Q8TEN6; Q8WUW0; Q96DI4"	"Ciliary landscape"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"4"	"0"	"71.8"	"51.2"	"69.5"	"76.3"	"70.0"	"80.9"	"111.6"	"474.2"	"487.6"	"685.5"	"590.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12797"	"Aspartyl/asparaginyl beta-hydroxylase OS=Homo sapiens OX=9606 GN=ASPH PE=1 SV=3"	"0.000"	""	"8"	"4"	"7"	"4"	"758"	"85.8"	"5.01"	"1869.41"	"11.44"	"4"	"3"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi"	"other molecular function"	"Pf05118, Pf05279, Pf13432"	"444"	"ENSG00000198363"	"ASPH"	"A0A0A0MSK8; A6NDF4; A6NHI2; B4DIC9; B4E2K4; B7ZM95; E5RGP5; F5H667; hsa:444; Q12797; Q6NXR7; Q8TB28; Q9H291; Q9H2C4; Q9NRI0; Q9NRI1; Q9Y4J0"	""	"Stimuli-sensing channels; Ion homeostasis"	"2"	"0"	"79.1"	"62.8"	"90.3"	"80.8"	"71.3"	"76.9"	"97.4"	"355.4"	"436.1"	"1221.6"	"1396.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60313"	"Dynamin-like 120 kDa protein, mitochondrial OS=Homo sapiens OX=9606 GN=OPA1 PE=1 SV=3"	"0.000"	""	"4"	"3"	"5"	"3"	"960"	"111.6"	"7.87"	"865.25"	"11.42"	"2"	"3"	"cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00350, Pf19434"	"4976"	"ENSG00000198836"	"OPA1"	"D3DNW4; E5KLJ5; E5KLJ6; E5KLJ7; E5KLK1; E5KLK2; hsa:4976; O60313"	"Orexin receptor pathway"	"Regulation of Apoptosis"	"2"	"0"	"54.4"	"41.5"	"57.4"	"55.4"	"47.9"	"54.8"	"70.2"	"143.5"	"141.5"	"359.9"	"527.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UQR0"	"Sex comb on midleg-like protein 2 OS=Homo sapiens OX=9606 GN=SCML2 PE=1 SV=1"	"0.000"	""	"6"	"3"	"6"	"3"	"700"	"77.2"	"8.54"	"957.55"	"11.42"	"3"	"3"	"other biological processes"	"nucleus"	""	"Pf00536, Pf02820, Pf12140, Pf17208"	"10389"	"ENSG00000102098"	"SCML2"	"hsa:10389; Q5JXE6; Q86U98; Q8IWD0; Q8NDP2; Q9UGC5; Q9UQR0"	""	""	"0"	"0"	"234.2"	"189.5"	"234.1"	"231.0"	"214.9"	"229.0"	"276.8"	"447.4"	"467.3"	"872.2"	"1176.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P289"	"Serine/threonine-protein kinase 26 OS=Homo sapiens OX=9606 GN=STK26 PE=1 SV=2"	"0.000"	""	"11"	"3"	"5"	"3"	"416"	"46.5"	"5.29"	"318.41"	"11.41"	"1"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"51765"	"ENSG00000134602"	"STK26"	"B2RAU2; hsa:51765; Q3ZB77; Q8NC04; Q9BXC3; Q9BXC4; Q9P289"	""	"Apoptotic cleavage of cellular proteins"	"1"	"0"	"211.0"	"131.0"	"230.4"	"201.0"	"187.0"	"183.2"	"228.2"	"586.6"	"560.9"	"1325.0"	"2338.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H9A5"	"CCR4-NOT transcription complex subunit 10 OS=Homo sapiens OX=9606 GN=CNOT10 PE=1 SV=1"	"0.000"	""	"4"	"2"	"4"	"2"	"744"	"82.3"	"7.78"	"401.58"	"11.32"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	""	"25904"	"ENSG00000182973"	"CNOT10"	"B7Z7L1; F8WAF2; hsa:25904; Q9BU30; Q9H5J7; Q9H8X1; Q9H9A5; Q9H9W0; Q9HAH3; Q9UFJ2"	"Ciliary landscape"	"Deadenylation of mRNA; TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"	"3"	"0"	"8.6"	"6.8"	"7.0"	"6.2"	"7.1"	"9.2"	"9.8"	"61.8"	"72.8"	"216.9"	"316.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P0U3"	"Sentrin-specific protease 1 OS=Homo sapiens OX=9606 GN=SENP1 PE=1 SV=2"	"0.000"	""	"7"	"3"	"6"	"3"	"644"	"73.4"	"8.47"	"1035.02"	"11.32"	"3"	"3"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf02902"	"29843"	"ENSG00000079387"	"SENP1"	"A8K7P5; hsa:29843; Q86XC8; Q9P0U3"	""	"RHOF GTPase cycle; SUMO is proteolytically processed"	"2"	"0"	"146.2"	"124.3"	"147.6"	"144.2"	"158.7"	"139.7"	"180.2"	"266.2"	"263.5"	"521.5"	"721.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96C57"	"Protein CUSTOS OS=Homo sapiens OX=9606 GN=CUSTOS PE=1 SV=2"	"0.000"	""	"15"	"3"	"6"	"3"	"262"	"28.2"	"9.42"	"2468.09"	"11.30"	"3"	"2"	"cell-cell signaling;signal transduction;other biological processes"	"nucleus"	""	""	"64897"	"ENSG00000157895"	"CUSTOS"	"hsa:64897; Q53HF0; Q96C57; Q9H9Z7"	""	""	"0"	"0"	"81.5"	"65.6"	"94.0"	"84.5"	"86.7"	"87.8"	"107.8"	"163.2"	"148.2"	"275.4"	"320.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NWS0"	"PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1"	"0.000"	""	"14"	"3"	"5"	"3"	"290"	"32.3"	"5.14"	"541.83"	"11.26"	"2"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf08190, Pf18201"	"55011"	"ENSG00000104872"	"PIH1D1"	"B4DGN7; B4E2X7; hsa:55011; Q9BVL0; Q9NWS0"	""	""	"0"	"0"	"101.7"	"72.4"	"120.8"	"109.1"	"101.5"	"99.3"	"143.0"	"478.2"	"475.8"	"1421.5"	"1458.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75955"	"Flotillin-1 OS=Homo sapiens OX=9606 GN=FLOT1 PE=1 SV=3"	"0.000"	""	"10"	"3"	"6"	"3"	"427"	"47.3"	"7.49"	"1064.17"	"11.23"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01145"	"10211"	"ENSG00000137312; ENSG00000206379; ENSG00000206480; ENSG00000230143; ENSG00000232280"	"FLOT1"	"B4DVY7; hsa:10211; O75955; Q969J8; Q9UHW1; Q9UNV8"	"Angiopoietin-like protein 8 regulatory pathway; Insulin signaling"	"RHOC GTPase cycle; RHOA GTPase cycle; RHOB GTPase cycle; Regulation of necroptotic cell death; Synaptic adhesion-like molecules"	"8"	"0"	"154.6"	"139.3"	"120.6"	"136.7"	"112.2"	"131.0"	"170.1"	"308.6"	"284.5"	"612.4"	"873.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P60842"	"Eukaryotic initiation factor 4A-I OS=Homo sapiens OX=9606 GN=EIF4A1 PE=1 SV=1"	"0.000"	""	"6"	"2"	"6"	"1"	"406"	"46.1"	"5.48"	"1479.61"	"11.21"	"2"	"2"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"1973"	"ENSG00000161960"	"EIF4A1"	"B2R6L8; D3DTP9; hsa:1973; J3QLC4; P04765; P60842; Q5U018; Q61516"	"Translation factors; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Interferon type I signaling pathways"	"ISG15 antiviral mechanism; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Deadenylation of mRNA"	"11"	"0"	"33.9"	"47.8"	"34.9"	"35.5"	"29.9"	"34.6"	"47.2"	"68.3"	"60.1"	"97.6"	"229.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5TBB1"	"Ribonuclease H2 subunit B OS=Homo sapiens OX=9606 GN=RNASEH2B PE=1 SV=1"	"0.000"	""	"15"	"4"	"5"	"4"	"312"	"35.1"	"9.13"	"904.31"	"11.20"	"2"	"3"	"cell cycle OR cell proliferation;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	""	"Pf09468, Pf17745"	"79621"	"ENSG00000136104"	"RNASEH2B"	"G3XAJ1; hsa:79621; Q05DR2; Q5TBB1; Q6PK48; Q9HAF7"	""	""	"0"	"0"	"160.6"	"124.7"	"178.9"	"156.7"	"153.0"	"169.7"	"205.9"	"870.1"	"890.7"	"2081.5"	"2773.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UEE9"	"Craniofacial development protein 1 OS=Homo sapiens OX=9606 GN=CFDP1 PE=1 SV=1"	"0.000"	""	"11"	"3"	"5"	"3"	"299"	"33.6"	"4.81"	"900.55"	"11.20"	"2"	"3"	"cell adhesion;cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	""	"Pf07572"	"10428"	"ENSG00000153774"	"CFDP1"	"hsa:10428; O00393; O00404; Q9UEE9; Q9UEF0; Q9UEF1; Q9UEF8"	""	""	"0"	"0"	"214.3"	"189.4"	"215.1"	"201.8"	"196.3"	"202.5"	"240.3"	"366.0"	"351.8"	"639.9"	"866.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IYB3"	"Serine/arginine repetitive matrix protein 1 OS=Homo sapiens OX=9606 GN=SRRM1 PE=1 SV=2"	"0.000"	""	"5"	"4"	"8"	"4"	"904"	"102.3"	"11.84"	"2270.41"	"11.19"	"4"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity"	"Pf01480"	"10250"	"ENSG00000133226"	"SRRM1"	"hsa:10250; O60585; Q5VVN4; Q8IYB3"	"mRNA processing"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle"	"7"	"0"	"136.9"	"99.1"	"145.6"	"127.7"	"142.8"	"155.7"	"188.1"	"505.1"	"511.4"	"1886.1"	"2990.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P32969"	"60S ribosomal protein L9 OS=Homo sapiens OX=9606 GN=RPL9 PE=1 SV=1"	"0.000"	""	"18"	"3"	"6"	"3"	"192"	"21.9"	"9.95"	"1098.05"	"11.17"	"3"	"3"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00347"	"6133"	"ENSG00000163682"	"RPL9; RPL9P7; RPL9P8; RPL9P9"	"hsa:6133; P32969"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis"	"14"	"0"	"129.7"	"121.6"	"124.3"	"115.9"	"126.5"	"131.4"	"160.6"	"278.4"	"284.5"	"717.9"	"1068.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51970"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 OS=Homo sapiens OX=9606 GN=NDUFA8 PE=1 SV=3"	"0.000"	""	"27"	"5"	"10"	"5"	"172"	"20.1"	"7.65"	"1853.37"	"11.12"	"5"	"3"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf06747"	"4702"	"ENSG00000119421"	"NDUFA8"	"B1AM93; hsa:4702; P51970; Q9Y6N0"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"832.5"	"813.1"	"614.9"	"620.7"	"717.8"	"634.9"	"871.3"	"1872.5"	"1753.2"	"4927.1"	"6432.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15143"	"Actin-related protein 2/3 complex subunit 1B OS=Homo sapiens OX=9606 GN=ARPC1B PE=1 SV=3"	"0.000"	""	"10"	"4"	"7"	"4"	"372"	"40.9"	"8.35"	"966.32"	"11.12"	"3"	"4"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400"	"10095"	"ENSG00000130429"	"ARPC1B"	"hsa:10095; O15143; Q9BU00"	"Pathogenic Escherichia coli infection; Microglia pathogen phagocytosis pathway"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; EPHB-mediated forward signaling"	"6"	"0"	"276.9"	"205.2"	"243.5"	"226.7"	"240.4"	"231.2"	"296.9"	"650.8"	"701.5"	"1542.5"	"2061.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15514"	"DNA-directed RNA polymerase II subunit RPB4 OS=Homo sapiens OX=9606 GN=POLR2D PE=1 SV=1"	"0.000"	""	"34"	"4"	"6"	"4"	"142"	"16.3"	"4.79"	"903.72"	"11.09"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf03874"	"5433"	"ENSG00000144231"	"POLR2D"	"hsa:5433; O15514; Q52LT4"	"Pyrimidine metabolism"	"Transcriptional regulation by small RNAs; Viral Messenger RNA Synthesis; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; mRNA Splicing - Major Pathway; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"42"	"0"	"362.3"	"232.6"	"354.1"	"300.0"	"290.0"	"302.9"	"415.1"	"526.5"	"488.3"	"748.9"	"973.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15437"	"Protein transport protein Sec23B OS=Homo sapiens OX=9606 GN=SEC23B PE=1 SV=2"	"0.000"	""	"3"	"2"	"7"	"1"	"767"	"86.4"	"6.89"	"1486.96"	"11.08"	"2"	"2"	"cell organization and biogenesis;transport"	"other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00626, Pf04810, Pf04811, Pf04815, Pf08033"	"10483"	"ENSG00000101310"	"SEC23B"	"D3DW33; hsa:10483; Q15437; Q503A9; Q5W183; Q9BS15; Q9BSI2; Q9H1D7"	"Sterol regulatory element-binding proteins (SREBP) signaling"	""	"1"	"1"	"88.4"	"68.3"	"98.0"	"89.4"	"95.8"	"74.9"	"105.5"	"194.9"	"188.5"	"412.8"	"559.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96A33"	"Coiled-coil domain-containing protein 47 OS=Homo sapiens OX=9606 GN=CCDC47 PE=1 SV=1"	"0.000"	""	"9"	"2"	"3"	"2"	"483"	"55.8"	"4.87"	"451.87"	"11.07"	"1"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;other cell component"	"translation activity;other molecular function"	"Pf07946"	"57003"	"ENSG00000108588"	"CCDC47"	"B2RAS8; D3DU20; hsa:57003; Q96A33; Q96D00; Q96JZ7; Q9H3E4; Q9NRG3"	""	""	"0"	"0"	"64.9"	"52.0"	"59.7"	"55.8"	"54.5"	"54.4"	"63.6"	"148.8"	"142.8"	"417.7"	"677.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8IXT5"	"RNA-binding protein 12B OS=Homo sapiens OX=9606 GN=RBM12B PE=1 SV=2"	""	""	"4"	"2"	"2"	"2"	"1001"	"118.0"	"6.81"	""	"11.01"	""	"2"	"other biological processes"	"nucleus;other cell component"	""	"Pf00076"	"389677"	"ENSG00000183808"	"RBM12B"	"A8MYB5; hsa:389677; Q8IXT5"	""	""	"0"	"0"	"48.5"	"57.7"	"44.3"	"55.7"	"60.6"	"62.9"	"68.0"	"106.5"	"97.9"	"191.1"	"292.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q00013"	"55 kDa erythrocyte membrane protein OS=Homo sapiens OX=9606 GN=MPP1 PE=1 SV=2"	"0.000"	""	"10"	"4"	"7"	"4"	"466"	"52.3"	"7.37"	"1048.76"	"11.01"	"3"	"4"	"other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;kinase activity"	"Pf00018, Pf00595, Pf00625"	"4354"	"ENSG00000130830"	"MPP1"	"B4DZV5; G3XAI1; hsa:4354; Q00013; Q2TSB6; Q5J7V5"	"MECP2 and associated Rett syndrome"	"Sensory processing of sound by outer hair cells of the cochlea"	"2"	"0"	"147.9"	"108.3"	"123.8"	"116.4"	"117.1"	"136.8"	"163.7"	"552.0"	"617.0"	"1178.0"	"1373.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BUJ2"	"Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2"	"0.000"	""	"5"	"5"	"8"	"4"	"856"	"95.7"	"6.92"	"1477.80"	"11.00"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00622, Pf02037, Pf13671"	"11100"	"ENSG00000105323"	"HNRNPUL1"	"B3KMW7; hsa:11100; O76022; Q6ZSZ0; Q7L8P4; Q8N6Z4; Q96G37; Q9BUJ2; Q9HAL3; Q9UG75"	""	""	"0"	"0"	"331.9"	"291.3"	"308.0"	"324.8"	"333.6"	"323.0"	"405.6"	"586.1"	"534.7"	"1021.9"	"1456.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60884"	"DnaJ homolog subfamily A member 2 OS=Homo sapiens OX=9606 GN=DNAJA2 PE=1 SV=1"	"0.000"	""	"10"	"2"	"3"	"2"	"412"	"45.7"	"6.48"	"321.39"	"11.00"	"1"	"2"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;other cell component"	"other molecular function"	"Pf00226, Pf00684, Pf01556"	"10294"	"ENSG00000069345"	"DNAJA2"	"B2R7L7; hsa:10294; O14711; O60884"	""	"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand"	"1"	"0"	"87.7"	"62.7"	"105.3"	"88.8"	"83.4"	"87.8"	"113.6"	"227.0"	"225.6"	"563.0"	"635.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61313"	"60S ribosomal protein L15 OS=Homo sapiens OX=9606 GN=RPL15 PE=1 SV=2"	"0.000"	""	"14"	"3"	"7"	"3"	"204"	"24.1"	"11.62"	"1573.84"	"10.96"	"3"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00827"	"6138"	"ENSG00000174748"	"RPL15"	"hsa:6138; P39030; P41051; P61313; Q5U0C0; Q642I1; Q6IPX6; Q8WYP2; Q96C44; Q9H2E5"	"Cytoplasmic ribosomal proteins"	"Major pathway of rRNA processing in the nucleolus and cytosol; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"309.3"	"285.3"	"328.6"	"311.4"	"322.3"	"312.7"	"445.9"	"750.3"	"697.5"	"1854.0"	"2977.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95793"	"Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2"	"0.000"	""	"6"	"3"	"6"	"3"	"577"	"63.1"	"9.44"	"1114.81"	"10.93"	"3"	"3"	"cell organization and biogenesis;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00035, Pf16482"	"6780"	"ENSG00000124214"	"STAU1"	"A8K9Z4; E1P5Y1; E1P608; hsa:6780; O95793; Q5JW29; Q6GTM4; Q9H5B4; Q9H5B5; Q9Y3Q2"	""	""	"0"	"0"	"84.3"	"65.6"	"100.5"	"85.2"	"94.4"	"88.1"	"92.6"	"147.6"	"144.6"	"274.2"	"325.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H4G4"	"Golgi-associated plant pathogenesis-related protein 1 OS=Homo sapiens OX=9606 GN=GLIPR2 PE=1 SV=3"	"0.000"	""	"17"	"2"	"6"	"2"	"154"	"17.2"	"9.41"	"1494.27"	"10.90"	"2"	"2"	"other biological processes"	"non-structural extracellular;other membranes;ER/Golgi"	"other molecular function"	"Pf00188"	"152007"	"ENSG00000122694"	"GLIPR2"	"hsa:152007; Q5VZR1; Q8N2S6; Q8WWC9; Q8WX36; Q9H4G4"	""	""	"0"	"0"	"211.5"	"203.5"	"173.4"	"161.3"	"184.9"	"203.6"	"264.0"	"392.2"	"331.0"	"630.8"	"911.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95248"	"Myotubularin-related protein 5 OS=Homo sapiens OX=9606 GN=SBF1 PE=1 SV=4"	"0.000"	""	"2"	"4"	"8"	"4"	"1868"	"208.3"	"6.90"	"1675.71"	"10.88"	"4"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf02141, Pf02893, Pf03456, Pf06602, Pf12335"	"6305"	"ENSG00000100241"	"SBF1"	"A0A024R4Z9; A6PVG9; G5E933; hsa:6305; O60228; O95248; Q5JXD8; Q5PPM2; Q96GR9; Q9UGB8"	""	"RAB GEFs exchange GTP for GDP on RABs; Synthesis of PIPs at the ER membrane"	"2"	"0"	"225.3"	"182.6"	"238.9"	"207.9"	"232.8"	"392.7"	"655.6"	"1763.1"	"1762.3"	"2156.8"	"2009.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P38606"	"V-type proton ATPase catalytic subunit A OS=Homo sapiens OX=9606 GN=ATP6V1A PE=1 SV=2"	"0.000"	""	"6"	"3"	"6"	"3"	"617"	"68.3"	"5.52"	"1163.58"	"10.87"	"3"	"3"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf00006, Pf02874, Pf16886"	"523"	"ENSG00000114573"	"ATP6V1A"	"B2RBR8; B7Z1R5; D3DN75; hsa:523; P38606; Q53YD9; Q96DY6; Q9UHY3"	"Proximal tubule transport"	"Amino acids regulate mTORC1; ROS and RNS production in phagocytes; Insulin receptor recycling; Transferrin endocytosis and recycling; Ion channel transport"	"6"	"0"	"87.5"	"88.1"	"87.3"	"78.7"	"76.4"	"76.8"	"102.7"	"186.6"	"184.1"	"386.0"	"685.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q07065"	"Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2"	"0.000"	""	"6"	"3"	"6"	"3"	"602"	"66.0"	"5.92"	"1003.03"	"10.85"	"3"	"3"	""	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	""	""	"10970"	"ENSG00000136026"	"CKAP4"	"hsa:10970; Q07065; Q504S5; Q53ES6"	""	"Neutrophil degranulation; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; RND2 GTPase cycle; RND3 GTPase cycle; Surfactant metabolism"	"6"	"0"	"106.8"	"79.6"	"107.6"	"95.5"	"91.0"	"95.7"	"128.5"	"244.0"	"212.5"	"448.9"	"658.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75052"	"Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein OS=Homo sapiens OX=9606 GN=NOS1AP PE=1 SV=3"	"0.000"	""	"9"	"3"	"5"	"3"	"506"	"56.1"	"6.30"	"690.22"	"10.83"	"2"	"3"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00640"	"9722"	"ENSG00000198929"	"NOS1AP"	"B7ZLF5; hsa:9722; O43564; O75052; Q3T551; Q5VU95"	"Sudden infant death syndrome (SIDS) susceptibility pathways"	""	"1"	"0"	"260.8"	"198.9"	"248.6"	"242.3"	"219.2"	"226.3"	"306.1"	"455.8"	"453.9"	"851.3"	"961.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61962"	"DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1"	"0.000"	""	"11"	"3"	"5"	"3"	"342"	"38.9"	"5.52"	"798.35"	"10.83"	"2"	"3"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00400"	"10238"	"ENSG00000136485"	"DCAF7"	"B4E039; D3DU14; hsa:10238; O15491; P61962; Q9DAE4"	"Ciliary landscape; DYRK1A involvement regarding cell proliferation in brain development"	"Neddylation; Association of TriC/CCT with target proteins during biosynthesis"	"4"	"0"	"192.8"	"161.6"	"201.6"	"192.2"	"184.8"	"199.3"	"256.7"	"386.9"	"369.4"	"714.9"	"936.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IUD2"	"ELKS/Rab6-interacting/CAST family member 1 OS=Homo sapiens OX=9606 GN=ERC1 PE=1 SV=1"	"0.000"	""	"3"	"3"	"6"	"3"	"1116"	"128.0"	"5.97"	"1162.21"	"10.83"	"3"	"3"	"cell-cell signaling;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf09457, Pf10174"	"23085"	"ENSG00000082805"	"ERC1"	"A2RU77; A7E295; D3DUP7; D3DUP8; hsa:23085; Q6NVK2; Q8IUD2; Q8IUD3; Q8IUD4; Q8IUD5; Q8NAS1; Q9NXN5; Q9UIK7; Q9UPS1"	""	""	"0"	"0"	"49.6"	"33.0"	"71.8"	"43.8"	"46.1"	"57.6"	"80.9"	"161.3"	"167.0"	"397.7"	"542.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2E4"	"Disco-interacting protein 2 homolog C OS=Homo sapiens OX=9606 GN=DIP2C PE=1 SV=2"	"0.000"	""	"3"	"3"	"6"	"3"	"1556"	"170.7"	"7.39"	"1009.13"	"10.81"	"3"	"3"	""	""	""	"Pf00501, Pf06464"	"22982"	"ENSG00000151240"	"DIP2C"	"B4DPI5; hsa:22982; Q5SS78; Q9Y2E4"	""	""	"0"	"0"	"48.1"	"34.8"	"40.0"	"37.1"	"33.0"	"41.0"	"60.4"	"138.0"	"163.4"	"403.8"	"600.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13693"	"Translationally-controlled tumor protein OS=Homo sapiens OX=9606 GN=TPT1 PE=1 SV=1"	"0.000"	""	"16"	"2"	"3"	"2"	"172"	"19.6"	"4.93"	"453.64"	"10.81"	"1"	"2"	"transport;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00838"	"7178"	"ENSG00000133112"	"TPT1"	"B2R7E5; hsa:7178; P13693; Q6YLS2; Q7Z4J4; Q8TBK7; Q96EE2; Q9UC70"	""	""	"0"	"0"	"22.8"	"15.1"	"32.6"	"24.8"	"28.3"	"18.6"	"29.0"	"144.2"	"127.3"	"493.7"	"2131.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NY12"	"H/ACA ribonucleoprotein complex subunit 1 OS=Homo sapiens OX=9606 GN=GAR1 PE=1 SV=1"	"0.000"	""	"22"	"4"	"6"	"4"	"217"	"22.3"	"10.92"	"836.93"	"10.79"	"3"	"3"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf04410"	"54433"	"ENSG00000109534"	"GAR1"	"hsa:54433; Q5MJQ2; Q9NY12"	""	"rRNA modification in the nucleus and cytosol; Telomere Extension By Telomerase"	"2"	"0"	"368.8"	"311.8"	"347.6"	"310.8"	"317.8"	"361.6"	"451.1"	"795.8"	"727.4"	"1900.4"	"2569.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NFH3"	"Nucleoporin Nup43 OS=Homo sapiens OX=9606 GN=NUP43 PE=1 SV=1"	"0.000"	""	"6"	"2"	"6"	"2"	"380"	"42.1"	"5.63"	"1168.33"	"10.78"	"2"	"2"	"cell cycle OR cell proliferation;transport;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf00400"	"348995"	"ENSG00000120253"	"NUP43"	"B4E2F0; hsa:348995; Q8NFH3; Q9H8S0"	""	"Regulation of HSF1-mediated heat shock response; SUMOylation of DNA damage response and repair proteins; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; RHO GTPases Activate Formins; Transport of Mature mRNA derived from an Intron-Containing Transcript; HCMV Late Events; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; HCMV Early Events; EML4 and NUDC in mitotic spindle formation; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Postmitotic nuclear pore complex (NPC) reformation"	"35"	"0"	"151.4"	"75.8"	"142.0"	"126.2"	"116.7"	"121.9"	"174.5"	"266.4"	"224.4"	"338.8"	"371.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBC3"	"DNA (cytosine-5)-methyltransferase 3B OS=Homo sapiens OX=9606 GN=DNMT3B PE=1 SV=1"	"0.000"	""	"4"	"2"	"5"	"2"	"853"	"95.7"	"8.43"	"588.56"	"10.77"	"1"	"2"	"DNA metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00145, Pf00855, Pf17980"	"1789"	"ENSG00000088305"	"DNMT3B"	"A2A2E2; B4DSM8; B4DSU1; E1P5M6; E1P5M7; E7EN63; E9PBF2; hsa:1789; Q9UBC3; Q9UBD4; Q9UJQ5; Q9UKA6; Q9UNE5; Q9Y5R9; Q9Y5S0"	"One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways; Mesodermal commitment pathway; Hematopoietic stem cell gene regulation by GABP alpha/beta complex; MTHFR deficiency"	"NoRC negatively regulates rRNA expression; PRC2 methylates histones and DNA; Defective pyroptosis; DNA methylation; SUMOylation of DNA methylation proteins"	"10"	"0"	"28.5"	"22.9"	"36.5"	"36.7"	"38.3"	"37.4"	"41.7"	"59.8"	"62.1"	"108.0"	"135.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UFW8"	"CGG triplet repeat-binding protein 1 OS=Homo sapiens OX=9606 GN=CGGBP1 PE=1 SV=2"	"0.000"	""	"19"	"3"	"6"	"3"	"167"	"18.8"	"8.95"	"991.88"	"10.76"	"3"	"3"	"cell organization and biogenesis;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	""	"8545"	"ENSG00000163320"	"CGGBP1"	"D3DU38; hsa:8545; O15183; Q9UFW8"	""	""	"0"	"0"	"231.2"	"188.7"	"222.0"	"218.5"	"229.0"	"218.8"	"287.5"	"425.7"	"391.7"	"627.7"	"699.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92879"	"CUGBP Elav-like family member 1 OS=Homo sapiens OX=9606 GN=CELF1 PE=1 SV=2"	"0.000"	""	"6"	"3"	"5"	"3"	"486"	"52.0"	"8.46"	"807.84"	"10.74"	"2"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"10658"	"ENSG00000149187"	"CELF1"	"B4E2U5; D3DQS0; F8W940; hsa:10658; Q4LE52; Q92879; Q9NP83; Q9NR06"	"Adipogenesis; mRNA processing"	""	"2"	"0"	"196.2"	"175.6"	"181.2"	"174.5"	"160.2"	"147.4"	"229.6"	"329.3"	"361.7"	"824.2"	"1175.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99986"	"Serine/threonine-protein kinase VRK1 OS=Homo sapiens OX=9606 GN=VRK1 PE=1 SV=1"	"0.000"	""	"14"	"5"	"7"	"5"	"396"	"45.4"	"8.91"	"1273.47"	"10.74"	"4"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;ER/Golgi;nucleus"	"kinase activity;other molecular function"	"Pf00069"	"7443"	"ENSG00000100749"	"VRK1"	"hsa:7443; Q3SYL2; Q99986"	""	"Nuclear Envelope Breakdown; Initiation of Nuclear Envelope (NE) Reformation"	"2"	"0"	"1075.6"	"791.3"	"1037.8"	"935.5"	"952.1"	"971.2"	"1281.5"	"1116.7"	"855.7"	"828.4"	"1039.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8NBT2"	"Kinetochore protein Spc24 OS=Homo sapiens OX=9606 GN=SPC24 PE=1 SV=2"	""	""	"17"	"2"	"2"	"1"	"197"	"22.5"	"4.70"	""	"10.72"	""	"2"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"24.2"	"23.3"	"33.4"	"32.4"	"25.7"	"27.8"	"33.6"	"43.0"	"44.8"	"91.6"	"111.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NQW7"	"Xaa-Pro aminopeptidase 1 OS=Homo sapiens OX=9606 GN=XPNPEP1 PE=1 SV=3"	"0.000"	""	"5"	"3"	"5"	"3"	"623"	"69.9"	"5.67"	"800.40"	"10.71"	"2"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00557, Pf01321, Pf16188, Pf16189"	"7511"	"ENSG00000108039"	"XPNPEP1"	"A8K071; G5E9Y2; G8JLB2; hsa:7511; O15250; Q53EX6; Q8N3Q0; Q96D23; Q9NQW7"	""	""	"0"	"0"	"66.7"	"52.9"	"69.1"	"62.4"	"68.6"	"70.3"	"97.1"	"267.6"	"273.4"	"869.2"	"1741.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N9N8"	"Probable RNA-binding protein EIF1AD OS=Homo sapiens OX=9606 GN=EIF1AD PE=1 SV=1"	"0.000"	""	"15"	"2"	"5"	"2"	"165"	"19.0"	"5.21"	"640.85"	"10.70"	"1"	"2"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01176"	"84285"	"ENSG00000175376"	"EIF1AD"	"B2R4N5; hsa:84285; Q8N9N8; Q9BSC1"	""	""	"0"	"0"	"124.3"	"111.3"	"734.3"	"184.2"	"242.5"	"176.2"	"178.2"	"329.4"	"325.6"	"738.8"	"1148.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99497"	"Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2"	"0.000"	""	"17"	"3"	"6"	"3"	"189"	"19.9"	"6.79"	"1121.80"	"10.68"	"3"	"3"	"cell-cell signaling;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf01965"	"11315"	"ENSG00000116288"	"PARK7"	"B2R4Z1; hsa:11315; O14805; Q6DR95; Q7LFU2; Q99497"	"Androgen receptor signaling pathway; Synaptic vesicle pathway; Parkinson's disease pathway"	"Late endosomal microautophagy; Aggrephagy; SUMOylation of transcription cofactors; Chaperone Mediated Autophagy"	"7"	"0"	"734.6"	"527.2"	"678.2"	"565.1"	"533.6"	"578.6"	"716.0"	"782.3"	"687.5"	"992.5"	"1264.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P39023"	"60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2"	"0.000"	""	"8"	"4"	"8"	"4"	"403"	"46.1"	"10.18"	"1202.86"	"10.67"	"4"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00297"	"6122"	"ENSG00000100316"	"RPL3"	"B2RDV9; hsa:6122; P39023; Q15548; Q5I0G0"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"407.5"	"310.6"	"402.8"	"337.1"	"360.7"	"399.4"	"531.3"	"870.9"	"761.7"	"1990.2"	"3104.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96D46"	"60S ribosomal export protein NMD3 OS=Homo sapiens OX=9606 GN=NMD3 PE=1 SV=1"	"0.000"	""	"6"	"3"	"5"	"3"	"503"	"57.6"	"7.14"	"845.63"	"10.67"	"2"	"3"	"transport;other biological processes"	"nucleus;other cell component"	"translation activity;other molecular function"	"Pf04981"	"51068"	"ENSG00000169251"	"NMD3"	"D3DNM7; hsa:51068; Q96D46; Q9Y2Z6"	""	""	"0"	"0"	"114.8"	"82.4"	"96.2"	"100.4"	"104.9"	"106.5"	"140.4"	"400.0"	"376.4"	"1432.8"	"1851.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62847"	"40S ribosomal protein S24 OS=Homo sapiens OX=9606 GN=RPS24 PE=1 SV=1"	"0.000"	""	"11"	"2"	"6"	"2"	"133"	"15.4"	"10.78"	"1093.35"	"10.66"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01282"	"6229"	"ENSG00000138326"	"RPS24"	"E7EPK6; hsa:6229; P16632; P62847; Q5T0P7; Q5T0P8; Q7Z3D1"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"66.9"	"44.6"	"71.9"	"63.6"	"52.7"	"63.0"	"95.7"	"146.1"	"170.5"	"377.2"	"629.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96SU4"	"Oxysterol-binding protein-related protein 9 OS=Homo sapiens OX=9606 GN=OSBPL9 PE=1 SV=2"	"0.000"	""	"9"	"5"	"9"	"5"	"736"	"83.1"	"6.18"	"2517.55"	"10.64"	"5"	"3"	"other metabolic processes;transport"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf00169, Pf01237"	"114883"	"ENSG00000117859"	"OSBPL9"	"B1AKJ8; B3KPQ4; D3DQ31; hsa:114883; Q5TFC0; Q6IA67; Q86YQ3; Q8NB17; Q8TAS8; Q96SK4; Q96SU4; Q9H9X2"	""	"Synthesis of bile acids and bile salts"	"1"	"0"	"283.9"	"236.7"	"274.7"	"246.7"	"244.2"	"268.1"	"330.2"	"590.6"	"596.2"	"1428.2"	"2008.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15381"	"Nuclear valosin-containing protein-like OS=Homo sapiens OX=9606 GN=NVL PE=1 SV=1"	"0.000"	""	"3"	"2"	"4"	"2"	"856"	"95.0"	"6.48"	"471.06"	"10.64"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00004, Pf16725, Pf17862"	"4931"	"ENSG00000143748"	"NVL"	"B4DMC4; B4DP98; hsa:4931; O15381; Q96EM7"	""	""	"0"	"0"	"58.5"	"57.6"	"78.8"	"72.6"	"87.0"	"84.3"	"94.9"	"130.1"	"115.6"	"229.6"	"283.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52435"	"DNA-directed RNA polymerase II subunit RPB11-a OS=Homo sapiens OX=9606 GN=POLR2J PE=1 SV=1"	"0.000"	""	"26"	"2"	"3"	"2"	"117"	"13.3"	"5.86"	"308.58"	"10.64"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf13656"	"5439"	"ENSG00000005075"	"POLR2J"	"A5D6V8; hsa:5439; O43375; P52435"	"Pyrimidine metabolism; Eukaryotic transcription initiation"	"Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; mRNA Splicing - Major Pathway; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"43"	"0"	"107.3"	"98.0"	"123.4"	"114.6"	"101.7"	"107.0"	"148.1"	"245.4"	"233.4"	"691.3"	"1107.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EY8"	"Corrinoid adenosyltransferase OS=Homo sapiens OX=9606 GN=MMAB PE=1 SV=1"	"0.000"	""	"16"	"3"	"6"	"3"	"250"	"27.4"	"8.60"	"1213.43"	"10.63"	"3"	"3"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf01923"	"326625"	"ENSG00000139428"	"MMAB"	"C5HU05; hsa:326625; Q96EY8; Q9BSH0"	"Vitamin B12 metabolism"	"Cobalamin (Cbl) metabolism; Defective MMAB causes MMA, cblB type"	"3"	"0"	"158.2"	"107.4"	"146.9"	"143.4"	"138.1"	"143.4"	"152.3"	"619.5"	"622.4"	"1364.3"	"1527.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P60520"	"Gamma-aminobutyric acid receptor-associated protein-like 2 OS=Homo sapiens OX=9606 GN=GABARAPL2 PE=1 SV=1"	"0.000"	""	"26"	"3"	"6"	"2"	"117"	"13.7"	"8.10"	"1032.25"	"10.63"	"3"	"3"	"cell organization and biogenesis;other metabolic processes;stress response;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf02991"	"11345"	"ENSG00000034713"	"GABARAPL2"	"hsa:11345; O08765; P60520; Q6FG91; Q9DCP8; Q9UQF7"	"Network map of SARS-CoV-2 signaling pathway; 2q37 copy number variation syndrome"	"Macroautophagy; TBC/RABGAPs"	"4"	"0"	"40.2"	"46.7"	"40.4"	"38.6"	"40.7"	"47.0"	"59.6"	"291.5"	"278.3"	"909.2"	"1233.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H8E8"	"Cysteine-rich protein 2-binding protein OS=Homo sapiens OX=9606 GN=KAT14 PE=1 SV=3"	"0.000"	""	"5"	"3"	"5"	"3"	"782"	"88.8"	"6.57"	"1027.12"	"10.63"	"2"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf13673"	"57325"	"ENSG00000149474"	"KAT14"	"A2A2I5; hsa:57325; Q96GW6; Q96IH3; Q9H8E8; Q9HBF0; Q9UIY5"	""	"Formation of WDR5-containing histone-modifying complexes; HATs acetylate histones"	"2"	"0"	"18.8"	"19.9"	"16.4"	"19.4"	"17.7"	"14.7"	"23.5"	"43.7"	"44.1"	"100.0"	"111.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q4G0J3"	"La-related protein 7 OS=Homo sapiens OX=9606 GN=LARP7 PE=1 SV=1"	"0.000"	""	"6"	"3"	"6"	"3"	"582"	"66.9"	"9.55"	"1224.73"	"10.62"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf05383, Pf08777"	"51574"	"ENSG00000174720"	"LARP7"	"B2ZHN6; hsa:51574; Q3B7A9; Q4G0J3; Q9P1S7; Q9Y3Z8"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"196.3"	"111.4"	"208.6"	"197.3"	"193.2"	"187.8"	"257.5"	"297.0"	"284.2"	"440.7"	"521.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96NB3"	"Zinc finger protein 830 OS=Homo sapiens OX=9606 GN=ZNF830 PE=1 SV=2"	"0.000"	""	"12"	"4"	"5"	"3"	"372"	"42.0"	"5.31"	"650.77"	"10.59"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf12874"	"91603"	"ENSG00000198783"	"ZNF830"	"hsa:91603; Q96F60; Q96GZ5; Q96NB3; Q9BU38"	"17q12 copy number variation syndrome"	"mRNA Splicing - Major Pathway; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	"6"	"0"	"172.6"	"132.6"	"197.2"	"178.2"	"175.9"	"137.5"	"201.5"	"264.1"	"232.6"	"454.9"	"749.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P67775"	"Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform OS=Homo sapiens OX=9606 GN=PPP2CA PE=1 SV=1"	"0.000"	""	"15"	"3"	"5"	"3"	"309"	"35.6"	"5.54"	"729.99"	"10.57"	"2"	"3"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00149"	"5515"	"ENSG00000113575"	"PPP2CA"	"hsa:5515; P05323; P13197; P67775"	"Sphingolipid pathway; TNF-alpha signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Dopamine metabolism; Mesodermal commitment pathway; Mesodermal commitment pathway; Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Wnt signaling pathway and pluripotency; PI3K-Akt signaling pathway; Cancer immunotherapy by CTLA4 blockade; FGFR3 signaling in chondrocyte proliferation and terminal differentiation; 16p11.2 proximal deletion syndrome; Glycogen synthesis and degradation; Cohesin complex - Cornelia de Lange syndrome"	"Separation of Sister Chromatids; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Regulation of TP53 Degradation; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Cyclin D associated events in G1; Disassembly of the destruction complex and recruitment of AXIN to the membrane; RAF activation; Cyclin A/B1/B2 associated events during G2/M transition; Beta-catenin phosphorylation cascade; Signaling by GSK3beta mutants; CTNNB1 S33 mutants aren't phosphorylated; CTNNB1 S37 mutants aren't phosphorylated; CTNNB1 S45 mutants aren't phosphorylated; CTNNB1 T41 mutants aren't phosphorylated; APC truncation mutants have impaired AXIN binding; AXIN missense mutants destabilize the destruction complex; Truncations of AMER1 destabilize the destruction complex; Spry regulation of FGF signaling; MASTL Facilitates Mitotic Progression; Regulation of glycolysis by fructose 2,6-bisphosphate metabolism; Initiation of Nuclear Envelope (NE) Reformation; Negative regulation of MAPK pathway; Platelet sensitization by LDL; CTLA4 inhibitory signaling; Inhibition of replication initiation of damaged DNA by RB1/E2F1; DARPP-32 events; PP2A-mediated dephosphorylation of key metabolic factors; ERKs are inactivated"	"52"	"0"	"151.0"	"119.3"	"112.9"	"130.8"	"123.6"	"114.6"	"160.1"	"281.9"	"252.4"	"547.0"	"692.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P28066"	"Proteasome subunit alpha type-5 OS=Homo sapiens OX=9606 GN=PSMA5 PE=1 SV=3"	"0.000"	""	"11"	"2"	"5"	"2"	"241"	"26.4"	"4.79"	"687.50"	"10.55"	"2"	"2"	"protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	""	"Pf00227, Pf10584"	"5686"	"ENSG00000143106"	"PSMA5"	"B2R8F6; B4E2V4; hsa:5686; P28066; Q3T1C1; Q6IBF7"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"63"	"0"	"50.3"	"34.2"	"54.5"	"52.8"	"48.9"	"59.3"	"83.3"	"150.9"	"123.6"	"374.7"	"1005.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96J01"	"THO complex subunit 3 OS=Homo sapiens OX=9606 GN=THOC3 PE=1 SV=1"	"0.000"	""	"8"	"3"	"6"	"3"	"351"	"38.7"	"6.09"	"1184.94"	"10.52"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00400, Pf08662, Pf12894"	"84321"	"ENSG00000051596"	"THOC3"	"hsa:84321; Q6NZ53; Q96J01"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"3"	"0"	"390.0"	"274.3"	"348.5"	"313.0"	"297.9"	"317.7"	"440.5"	"671.6"	"628.7"	"1423.1"	"2192.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23378"	"Glycine dehydrogenase (decarboxylating), mitochondrial OS=Homo sapiens OX=9606 GN=GLDC PE=1 SV=2"	"0.000"	""	"5"	"3"	"5"	"3"	"1020"	"112.7"	"7.11"	"797.51"	"10.50"	"2"	"3"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01212, Pf02347"	"2731"	"ENSG00000178445"	"GLDC"	"hsa:2731; P23378; Q2M2F8"	"Metabolic Epileptic Disorders"	"Glycine degradation"	"2"	"0"	"87.8"	"58.9"	"88.9"	"75.7"	"75.9"	"84.5"	"116.5"	"381.6"	"394.7"	"722.4"	"899.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2Z4"	"Tyrosine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=YARS2 PE=1 SV=2"	"0.000"	""	"8"	"2"	"6"	"2"	"477"	"53.2"	"8.98"	"950.37"	"10.48"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00579"	"51067"	"ENSG00000139131"	"YARS2"	"D3DUW8; hsa:51067; Q9H817; Q9Y2Z4"	"Orexin receptor pathway"	"Mitochondrial tRNA aminoacylation"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NFW8"	"N-acylneuraminate cytidylyltransferase OS=Homo sapiens OX=9606 GN=CMAS PE=1 SV=2"	"0.000"	""	"7"	"2"	"6"	"2"	"434"	"48.3"	"7.93"	"1251.65"	"10.48"	"2"	"2"	"other metabolic processes"	"nucleus"	"other molecular function"	"Pf02348"	"55907"	"ENSG00000111726"	"CMAS"	"hsa:55907; Q8NFW8; Q96AX5; Q9NQZ0"	""	"Sialic acid metabolism"	"1"	"0"	"92.8"	"73.8"	"91.8"	"83.8"	"80.9"	"81.4"	"129.5"	"243.8"	"241.7"	"532.9"	"781.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P00505"	"Aspartate aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=GOT2 PE=1 SV=3"	"0.000"	""	"6"	"2"	"5"	"2"	"430"	"47.5"	"9.01"	"1497.16"	"10.46"	"2"	"1"	"other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;mitochondrion"	"other molecular function"	"Pf00155"	"2806"	"ENSG00000125166"	"GOT2"	"B4DJA6; E7ERW2; hsa:2806; P00505; Q53FL3; Q9BWA3"	"Alanine and aspartate metabolism; Amino acid metabolism; Metabolic reprogramming in colon cancer; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"Glyoxylate metabolism and glycine degradation; Gluconeogenesis; Aspartate and asparagine metabolism; Glutamate and glutamine metabolism; Degradation of cysteine and homocysteine"	"11"	"0"	"314.6"	"178.2"	"323.4"	"282.9"	"288.6"	"341.0"	"466.2"	"455.4"	"532.9"	"798.1"	"1206.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P0C0S5"	"Histone H2A.Z OS=Homo sapiens OX=9606 GN=H2AZ1 PE=1 SV=2"	"0.000"	""	"20"	"2"	"7"	"1"	"128"	"13.5"	"10.58"	"1057.90"	"10.40"	"2"	"2"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125, Pf16211"	"3015"	"ENSG00000164032"	"H2AZ1"	"B2RD56; hsa:3015; P0C0S5; P17317; Q6I9U0"	"Proteasome degradation; Retinoblastoma gene in cancer; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma"	"Amyloid fiber formation"	"4"	"0"	"43.0"	"22.1"	"49.4"	"38.1"	"41.0"	"39.2"	"54.4"	"83.9"	"89.0"	"153.1"	"203.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86UV5"	"Ubiquitin carboxyl-terminal hydrolase 48 OS=Homo sapiens OX=9606 GN=USP48 PE=1 SV=1"	"0.000"	""	"5"	"4"	"7"	"4"	"1035"	"119.0"	"6.05"	"1889.71"	"10.39"	"4"	"3"	"protein metabolism;other metabolic processes"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf00443"	"84196"	"ENSG00000090686"	"USP48"	"B7ZKS7; hsa:84196; Q2M3I4; Q5SZI4; Q5T3T5; Q6NX53; Q86UV5; Q8N3F6; Q96F64; Q96IQ3; Q9H5N3; Q9H5T7; Q9NUJ6; Q9NXR0"	""	"Ub-specific processing proteases"	"1"	"0"	"23.6"	"24.4"	"31.0"	"20.5"	"25.6"	"32.4"	"35.5"	"196.9"	"217.7"	"620.5"	"706.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q3B7T1"	"Erythroid differentiation-related factor 1 OS=Homo sapiens OX=9606 GN=EDRF1 PE=1 SV=1"	"0.000"	""	"4"	"5"	"8"	"5"	"1238"	"138.4"	"6.33"	"1016.28"	"10.39"	"4"	"4"	"other biological processes"	"nucleus"	""	""	"26098"	"ENSG00000107938"	"EDRF1"	"B2RC65; hsa:26098; Q3B7T1; Q3KR40; Q4G190; Q5VZQ4; Q8IZ74; Q9Y3W4"	""	""	"0"	"0"	"56.8"	"49.5"	"47.0"	"51.7"	"49.0"	"46.2"	"58.7"	"193.6"	"187.4"	"493.9"	"705.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43865"	"S-adenosylhomocysteine hydrolase-like protein 1 OS=Homo sapiens OX=9606 GN=AHCYL1 PE=1 SV=2"	"0.000"	""	"6"	"4"	"7"	"4"	"530"	"58.9"	"6.89"	"1930.99"	"10.38"	"4"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00670, Pf05221"	"10768"	"ENSG00000168710"	"AHCYL1"	"B4E168; hsa:10768; O43865; Q2TAJ6; Q502W8; Q5VSM0; Q6P171; Q96PK4; Q9UG84"	"Trans-sulfuration, one-carbon metabolism and related pathways"	"Role of phospholipids in phagocytosis; FCERI mediated Ca+2 mobilization; FCGR3A-mediated IL10 synthesis; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Ion homeostasis; Regulation of insulin secretion; VEGFR2 mediated cell proliferation; PLC beta mediated events; DAG and IP3 signaling; CLEC7A (Dectin-1) induces NFAT activation"	"11"	"0"	"473.4"	"437.0"	"450.8"	"430.2"	"414.4"	"450.6"	"532.0"	"772.6"	"779.1"	"1739.9"	"2944.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UHR4"	"Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 OS=Homo sapiens OX=9606 GN=BAIAP2L1 PE=1 SV=2"	"0.000"	""	"8"	"3"	"6"	"3"	"511"	"56.8"	"8.68"	"1227.48"	"10.38"	"3"	"3"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus"	"cytoskeletal activity;other molecular function"	"Pf08397, Pf14604"	"55971"	"ENSG00000006453"	"BAIAP2L1"	"A4D268; hsa:55971; Q75L21; Q75L22; Q96CV4; Q9H5F5; Q9UHR4; Q9Y2M8"	""	"RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOF GTPase cycle"	"4"	"0"	"209.9"	"111.0"	"250.9"	"217.8"	"210.2"	"239.5"	"307.2"	"268.6"	"242.7"	"264.1"	"291.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UQ13"	"Leucine-rich repeat protein SHOC-2 OS=Homo sapiens OX=9606 GN=SHOC2 PE=1 SV=2"	"0.000"	""	"8"	"2"	"3"	"2"	"582"	"64.8"	"8.46"	"304.87"	"10.37"	"1"	"2"	"signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf13855"	"8036"	"ENSG00000108061"	"SHOC2"	"A8K9W8; B3KR23; hsa:8036; O76063; Q5VZS8; Q5VZS9; Q9UQ13"	"Ras signaling; 22q11.2 copy number variation syndrome; Autophagy in pancreatic ductal adenocarcinoma"	"RAF activation; SHOC2 M1731 mutant abolishes MRAS complex function; Gain-of-function MRAS complexes activate RAF signaling"	"6"	"0"	"36.9"	"22.4"	"38.9"	"37.6"	"35.5"	"32.5"	"52.7"	"86.3"	"74.0"	"118.2"	"122.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15020"	"Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1"	"0.000"	""	"4"	"4"	"6"	"4"	"963"	"109.9"	"5.57"	"778.75"	"10.31"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00076, Pf05391, Pf16605"	"9733"	"ENSG00000075856"	"SART3"	"A8K2E4; B7ZKM0; hsa:9733; Q15020; Q2M2H0; Q58F06; Q8IUS1; Q96J95"	""	""	"0"	"0"	"603.5"	"504.6"	"533.4"	"493.2"	"492.8"	"481.5"	"601.0"	"699.7"	"685.3"	"896.9"	"1175.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13131"	"5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens OX=9606 GN=PRKAA1 PE=1 SV=4"	"0.000"	""	"8"	"3"	"6"	"3"	"559"	"64.0"	"8.12"	"1124.78"	"10.29"	"2"	"3"	"cell-cell signaling;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;kinase activity;other molecular function"	"Pf00069, Pf16579"	"5562"	"ENSG00000132356"	"PRKAA1"	"A8MTQ6; B2R7E1; hsa:5562; O00286; Q13131; Q5D0E1; Q86VS1; Q9UNQ4"	"AMP-activated protein kinase signaling; Target of rapamycin signaling; Energy metabolism; Thyroxine (thyroid hormone) production; Sterol regulatory element-binding proteins (SREBP) signaling; SREBF and miR33 in cholesterol and lipid homeostasis; Leptin signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; mir-124 predicted interactions with cell cycle and differentiation ; ATM signaling in development and disease ; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Leptin and adiponectin; Lipid metabolism pathway; PI3K-Akt signaling pathway; Thermogenesis; Nonalcoholic fatty liver disease; Synaptic signaling pathways associated with autism spectrum disorder; Hippo signaling regulation pathways; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Head and neck squamous cell carcinoma; IL-18 signaling pathway; Insulin signaling; 1q21.1 copy number variation syndrome; Autophagy; p53 transcriptional gene network; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Pleural mesothelioma; Disturbed pathways in Duchenne Muscular Dystrophy"	"Activation of AMPK downstream of NMDARs; Regulation of TP53 Activity through Phosphorylation; TP53 Regulates Metabolic Genes; Macroautophagy; Energy dependent regulation of mTOR by LKB1-AMPK"	"35"	"0"	"81.1"	"50.7"	"88.2"	"68.5"	"71.5"	"75.1"	"99.8"	"207.7"	"226.3"	"639.2"	"885.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15067"	"Peroxisomal acyl-coenzyme A oxidase 1 OS=Homo sapiens OX=9606 GN=ACOX1 PE=1 SV=3"	"0.000"	""	"7"	"3"	"4"	"3"	"660"	"74.4"	"8.16"	"452.04"	"10.26"	"1"	"3"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle"	"other molecular function"	"Pf01756, Pf02770, Pf14749"	"51"	"ENSG00000161533"	"ACOX1"	"A8K6X8; A8KAA0; B4DK61; F5GYQ8; hsa:51; Q12863; Q15067; Q15068; Q15101; Q16131; Q7Z3W5; Q9UD31"	"Estrogen receptor pathway; Nuclear receptors meta-pathway; PPAR signaling pathway; Eicosanoid metabolism via cyclooxygenases (COX); Eicosanoid metabolism via lipooxygenases (LOX); Omega-3 / omega-6 fatty acid synthesis"	"TYSND1 cleaves peroxisomal proteins"	"8"	"0"	"63.7"	"37.6"	"62.8"	"55.5"	"51.9"	"63.4"	"88.0"	"239.8"	"228.6"	"708.3"	"1095.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6G9"	"Cytoplasmic dynein 1 light intermediate chain 1 OS=Homo sapiens OX=9606 GN=DYNC1LI1 PE=1 SV=3"	"0.000"	""	"7"	"3"	"6"	"3"	"523"	"56.5"	"6.42"	"1101.43"	"10.25"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf05783"	"51143"	"ENSG00000144635"	"DYNC1LI1"	"A2RRG7; hsa:51143; Q53HC8; Q53HK7; Q9Y6G9"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; MHC class II antigen presentation; HCMV Early Events; Neutrophil degranulation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Aggrephagy"	"15"	"0"	"189.1"	"156.0"	"175.9"	"176.3"	"166.0"	"172.8"	"215.7"	"338.3"	"325.4"	"830.5"	"1152.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16513"	"Serine/threonine-protein kinase N2 OS=Homo sapiens OX=9606 GN=PKN2 PE=1 SV=1"	"0.000"	""	"3"	"3"	"6"	"3"	"984"	"112.0"	"6.30"	"1071.42"	"10.22"	"3"	"3"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00433, Pf02185"	"5586"	"ENSG00000065243"	"PKN2"	"B4DQ21; B4DTP5; B4DVG1; D3DT24; hsa:5586; Q08AF4; Q16513; Q9H1W4"	"PI3K-Akt signaling pathway"	"RAC1 GTPase cycle; RHO GTPases activate PKNs; RHOC GTPase cycle; RHOA GTPase cycle; RHOB GTPase cycle"	"6"	"0"	"38.3"	"36.9"	"44.3"	"49.2"	"40.0"	"40.4"	"53.4"	"133.5"	"120.4"	"320.2"	"387.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O43301"	"Heat shock 70 kDa protein 12A OS=Homo sapiens OX=9606 GN=HSPA12A PE=1 SV=2"	""	""	"6"	"3"	"3"	"3"	"675"	"74.9"	"6.77"	""	"10.19"	""	"3"	""	"nucleus;other cell component"	"other molecular function"	""	"259217"	"ENSG00000165868"	"HSPA12A"	"hsa:259217; O43301"	""	"Regulation of HSF1-mediated heat shock response"	"1"	"0"	"54.9"	"54.8"	"47.1"	"61.3"	"55.4"	"48.6"	"64.5"	"148.9"	"157.7"	"332.8"	"476.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14314"	"Glucosidase 2 subunit beta OS=Homo sapiens OX=9606 GN=PRKCSH PE=1 SV=2"	"0.000"	""	"8"	"5"	"8"	"5"	"528"	"59.4"	"4.41"	"1973.57"	"10.19"	"5"	"3"	"protein metabolism;other metabolic processes;developmental processes;signal transduction"	"ER/Golgi;other cell component"	"other molecular function"	"Pf12999, Pf13015, Pf13202"	"5589"	"ENSG00000130175"	"PRKCSH"	"A8K318; hsa:5589; P14314; Q96BU9; Q96D06; Q9P0W9"	""	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Advanced glycosylation endproduct receptor signaling; Maturation of spike protein; Calnexin/calreticulin cycle; Maturation of spike protein"	"7"	"0"	"1142.7"	"857.5"	"1041.9"	"917.6"	"933.8"	"967.6"	"1172.1"	"1220.6"	"1224.7"	"1510.5"	"1881.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09884"	"DNA polymerase alpha catalytic subunit OS=Homo sapiens OX=9606 GN=POLA1 PE=1 SV=2"	"0.000"	""	"2"	"3"	"5"	"3"	"1462"	"165.8"	"5.85"	"574.95"	"10.19"	"2"	"3"	"cell cycle OR cell proliferation;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00136, Pf03104, Pf08996, Pf12254"	"5422"	"ENSG00000101868"	"POLA1"	"hsa:5422; P09884; Q86UQ7"	"Retinoblastoma gene in cancer; Pyrimidine metabolism; DNA replication"	"Activation of the pre-replicative complex; Defective pyroptosis; G1/S-Specific Transcription; Inhibition of replication initiation of damaged DNA by RB1/E2F1; Polymerase switching on the C-strand of the telomere; Telomere C-strand synthesis initiation; DNA replication initiation; Polymerase switching; Removal of the Flap Intermediate"	"13"	"0"	"73.0"	"61.0"	"78.3"	"73.1"	"61.4"	"68.8"	"83.3"	"238.8"	"239.2"	"900.0"	"1069.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IYB5"	"Stromal membrane-associated protein 1 OS=Homo sapiens OX=9606 GN=SMAP1 PE=1 SV=2"	"0.000"	""	"7"	"2"	"3"	"2"	"467"	"50.4"	"8.75"	"371.78"	"10.18"	"1"	"2"	"other biological processes"	"plasma membrane;other membranes;other cell component"	"enzyme regulator activity;other molecular function"	"Pf01412"	"60682"	"ENSG00000112305"	"SMAP1"	"hsa:60682; Q53H70; Q5SYQ2; Q6PK24; Q8IYB5; Q8NDH4; Q96L38; Q96L39; Q9H8X4"	""	""	"0"	"0"	"39.2"	"39.4"	"43.6"	"48.7"	"46.7"	"31.5"	"50.1"	"118.9"	"132.3"	"260.0"	"276.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43813"	"Glutathione S-transferase LANCL1 OS=Homo sapiens OX=9606 GN=LANCL1 PE=1 SV=1"	"0.000"	""	"9"	"3"	"6"	"3"	"399"	"45.3"	"7.75"	"1091.99"	"10.16"	"3"	"3"	"other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf05147"	"10314"	"ENSG00000115365"	"LANCL1"	"hsa:10314; O43813"	""	""	"0"	"0"	"116.9"	"122.6"	"115.1"	"104.0"	"122.3"	"92.8"	"147.6"	"270.9"	"310.0"	"750.2"	"1158.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H9B1"	"Histone-lysine N-methyltransferase EHMT1 OS=Homo sapiens OX=9606 GN=EHMT1 PE=1 SV=4"	"0.000"	""	"4"	"4"	"7"	"4"	"1298"	"141.4"	"5.76"	"1402.14"	"10.15"	"4"	"3"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00856, Pf05033, Pf12796"	"79813"	"ENSG00000181090"	"EHMT1"	"B1AQ58; B1AQ59; hsa:79813; Q86X08; Q8TCN7; Q96F53; Q96JF1; Q96KH4; Q9H9B1"	"Histone modifications; MTHFR deficiency; Kleefstra syndrome"	"Senescence-Associated Secretory Phenotype (SASP); Regulation of TP53 Activity through Methylation; Transcriptional Regulation by E2F6; Transcriptional Regulation by VENTX; PKMTs methylate histone lysines"	"8"	"0"	"149.7"	"118.1"	"139.8"	"135.4"	"133.9"	"121.2"	"154.9"	"207.6"	"196.1"	"407.4"	"588.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q02218"	"2-oxoglutarate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=OGDH PE=1 SV=3"	"0.000"	""	"4"	"3"	"6"	"3"	"1023"	"115.9"	"6.86"	"1061.92"	"10.15"	"3"	"3"	"protein metabolism;other metabolic processes;developmental processes"	"other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00676, Pf02779, Pf16078, Pf16870"	"4967"	"ENSG00000105953"	"OGDH"	"B4E2U9; D3DVL0; E9PBM1; hsa:4967; Q02218; Q96DD3; Q9UDX0"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Thiamine metabolic pathways; 7q11.23 copy number variation syndrome; TCA cycle (aka Krebs or citric acid cycle)"	"Lysine catabolism; Glyoxylate metabolism and glycine degradation; Citric acid cycle (TCA cycle)"	"8"	"0"	"177.9"	"141.8"	"206.1"	"190.5"	"162.1"	"174.3"	"206.0"	"250.0"	"237.6"	"360.7"	"542.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13451"	"Peptidyl-prolyl cis-trans isomerase FKBP5 OS=Homo sapiens OX=9606 GN=FKBP5 PE=1 SV=2"	"0.000"	""	"9"	"2"	"3"	"2"	"457"	"51.2"	"5.90"	"476.04"	"10.13"	"1"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00254, Pf00515"	"2289"	"ENSG00000096060"	"FKBP5"	"F5H7R1; hsa:2289; Q13451; Q59EB8; Q5TGM6"	"Androgen receptor network in prostate cancer; Farnesoid X receptor pathway; Nuclear receptors meta-pathway; MECP2 and associated Rett syndrome"	"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; ESR-mediated signaling; MECP2 regulates neuronal receptors and channels"	"7"	"0"	"6.0"	"8.5"	"9.5"	"7.7"	"8.7"	"7.9"	"8.6"	"25.5"	"16.2"	"135.3"	"284.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75530"	"Polycomb protein EED OS=Homo sapiens OX=9606 GN=EED PE=1 SV=2"	"0.000"	""	"5"	"2"	"5"	"2"	"441"	"50.2"	"7.03"	"682.39"	"10.10"	"1"	"2"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00400"	"8726"	"ENSG00000074266"	"EED"	"A8K7V5; hsa:8726; O00149; O75530; Q6NTH2; Q7LDA5; Q7LDG8; Q86VV2; Q9UNY7"	"Histone modifications; Interactome of polycomb repressive complex 2 (PRC2) ; Tumor suppressor activity of SMARCB1; Epithelial to mesenchymal transition in colorectal cancer; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; Pleural mesothelioma; 5q35 copy number variation"	"HCMV Early Events; Oxidative Stress Induced Senescence; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6; Activation of anterior HOX genes in hindbrain development during early embryogenesis; PKMTs methylate histone lysines; PRC2 methylates histones and DNA; Defective pyroptosis"	"15"	"0"	"19.0"	"17.5"	"31.4"	"31.1"	"24.7"	"33.7"	"38.9"	"94.5"	"88.5"	"380.9"	"517.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5K6"	"CD2-associated protein OS=Homo sapiens OX=9606 GN=CD2AP PE=1 SV=1"	"0.000"	""	"5"	"3"	"6"	"3"	"639"	"71.4"	"6.40"	"1070.69"	"10.09"	"3"	"3"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00018, Pf14604"	"23607"	"ENSG00000198087"	"CD2AP"	"A6NL34; hsa:23607; Q5VYA3; Q9UG97; Q9Y5K6"	"Primary focal segmental glomerulosclerosis (FSGS); Nephrotic syndrome; Genes controlling nephrogenesis; GDNF signaling"	"Nephrin family interactions"	"5"	"0"	"150.1"	"129.1"	"161.4"	"145.0"	"129.9"	"138.9"	"172.9"	"340.3"	"356.1"	"860.0"	"1184.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P48735"	"Isocitrate dehydrogenase [NADP], mitochondrial OS=Homo sapiens OX=9606 GN=IDH2 PE=1 SV=2"	"0.000"	""	"7"	"3"	"7"	"3"	"452"	"50.9"	"8.69"	"1460.96"	"10.08"	"3"	"2"	"other metabolic processes"	"cytosol;mitochondrion;other cytoplasmic organelle"	"other molecular function"	"Pf00180"	"3418"	"ENSG00000182054"	"IDH2"	"B2R6L6; B4DFL2; hsa:3418; P48735; Q96GT3"	"VEGFA-VEGFR2 signaling; Metabolic reprogramming in colon cancer; Cerebral organic acidurias, including diseases; TCA cycle (aka Krebs or citric acid cycle)"	"Transcriptional activation of mitochondrial biogenesis; Citric acid cycle (TCA cycle)"	"6"	"0"	"239.7"	"205.9"	"205.8"	"193.0"	"219.2"	"212.2"	"290.6"	"424.2"	"427.2"	"819.5"	"918.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P98179"	"RNA-binding protein 3 OS=Homo sapiens OX=9606 GN=RBM3 PE=1 SV=1"	"0.000"	""	"22"	"2"	"5"	"2"	"157"	"17.2"	"8.91"	"690.65"	"10.08"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"translation activity"	"Pf00076"	"5935"	"ENSG00000102317"	"RBM3"	"hsa:5935; P98179"	""	""	"0"	"0"	"200.4"	"623.9"	"41.2"	"64.6"	"88.0"	"87.2"	"147.4"	"298.2"	"204.5"	"488.7"	"987.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13243"	"Serine/arginine-rich splicing factor 5 OS=Homo sapiens OX=9606 GN=SRSF5 PE=1 SV=1"	"0.000"	""	"17"	"4"	"6"	"3"	"272"	"31.2"	"11.59"	"838.08"	"10.08"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00076"	"6430"	"ENSG00000100650"	"SRSF5"	"hsa:6430; O14797; Q13243; Q16662; Q49AD6; Q6FGE0"	"mRNA processing"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"6"	"0"	"430.4"	"365.6"	"391.4"	"371.4"	"367.1"	"362.5"	"478.9"	"609.6"	"527.6"	"986.3"	"1553.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5Q9"	"General transcription factor 3C polypeptide 3 OS=Homo sapiens OX=9606 GN=GTF3C3 PE=1 SV=1"	"0.000"	""	"2"	"2"	"6"	"2"	"886"	"101.2"	"5.07"	"1199.17"	"10.08"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13181"	"9330"	"ENSG00000119041"	"GTF3C3"	"hsa:9330; Q4ZG48; Q86XJ8; Q8WX84; Q96B44; Q9H5I8; Q9NT97; Q9Y5Q9"	""	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter"	"3"	"0"	"252.1"	"182.9"	"243.3"	"232.9"	"224.7"	"225.4"	"253.7"	"364.0"	"376.5"	"885.4"	"1303.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14C86"	"GTPase-activating protein and VPS9 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=GAPVD1 PE=1 SV=2"	"0.000"	""	"3"	"3"	"6"	"3"	"1478"	"164.9"	"5.22"	"951.41"	"10.07"	"3"	"3"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00616, Pf02204, Pf18151"	"26130"	"ENSG00000165219"	"GAPVD1"	"A8MYK3; B0QZ62; B0QZ63; B0QZ64; hsa:26130; Q14C76; Q14C86; Q2Q1W1; Q8ND92; Q8WU86; Q96CZ4; Q9NXQ1; Q9P207; Q9Y4N0"	""	"RAB GEFs exchange GTP for GDP on RABs; Clathrin-mediated endocytosis"	"2"	"0"	"126.4"	"100.7"	"123.5"	"130.0"	"127.2"	"127.0"	"156.7"	"239.0"	"245.9"	"595.1"	"761.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96PZ0"	"Pseudouridylate synthase 7 homolog OS=Homo sapiens OX=9606 GN=PUS7 PE=1 SV=2"	"0.000"	""	"7"	"3"	"5"	"3"	"661"	"75.0"	"6.37"	"638.80"	"10.05"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf01142"	"54517"	"ENSG00000091127"	"PUS7"	"hsa:54517; Q75MG4; Q96PZ0; Q9NX19"	""	"tRNA modification in the nucleus and cytosol"	"1"	"0"	"102.3"	"66.3"	"95.1"	"90.6"	"91.9"	"97.3"	"116.3"	"207.7"	"225.1"	"473.6"	"701.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46063"	"ATP-dependent DNA helicase Q1 OS=Homo sapiens OX=9606 GN=RECQL PE=1 SV=3"	"0.000"	""	"6"	"3"	"5"	"3"	"649"	"73.4"	"7.88"	"949.40"	"10.05"	"2"	"3"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf16124"	"5965"	"ENSG00000004700"	"RECQL"	"A8K6G2; hsa:5965; P46063"	"Progeria-associated lipodystrophy"	""	"1"	"0"	"132.7"	"113.6"	"116.3"	"126.9"	"128.6"	"154.9"	"209.4"	"387.6"	"406.0"	"729.5"	"849.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8IUF8"	"Ribosomal oxygenase 2 OS=Homo sapiens OX=9606 GN=RIOX2 PE=1 SV=1"	""	""	"6"	"1"	"2"	"1"	"465"	"52.8"	"6.70"	""	"10.04"	""	"1"	"cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf08007, Pf20514"	"84864"	"ENSG00000170854"	"RIOX2"	"D3DN35; hsa:84864; Q6AHW4; Q6SKS0; Q8IU69; Q8IUF6; Q8IUF7; Q8IUF8; Q96C17; Q96KB0"	""	"HDMs demethylate histones"	"1"	"0"	"6.2"	"0.0"	"8.6"	"6.9"	"5.8"	"6.2"	"10.1"	"25.8"	"22.4"	"78.7"	"89.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46939"	"Utrophin OS=Homo sapiens OX=9606 GN=UTRN PE=1 SV=2"	"0.000"	""	"1"	"3"	"7"	"3"	"3433"	"394.2"	"5.33"	"1573.16"	"10.04"	"3"	"2"	"cell-cell signaling;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00307, Pf00435, Pf00569, Pf09068, Pf09069"	"7402"	"ENSG00000152818"	"UTRN"	"hsa:7402; P46939; Q5SYY1; Q5SZ57; Q9UJ40"	"Primary focal segmental glomerulosclerosis (FSGS)"	"EGR2 and SOX10-mediated initiation of Schwann cell myelination"	"2"	"0"	"72.5"	"60.0"	"74.1"	"74.0"	"70.8"	"81.9"	"86.2"	"145.3"	"148.0"	"316.0"	"419.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5T1M5"	"FK506-binding protein 15 OS=Homo sapiens OX=9606 GN=FKBP15 PE=1 SV=2"	"0.000"	""	"3"	"2"	"3"	"2"	"1219"	"133.5"	"5.20"	"284.59"	"10.03"	"1"	"2"	"transport"	"other membranes;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00254"	"23307"	"ENSG00000119321"	"FKBP15"	"hsa:23307; Q05DK8; Q5T1M2; Q5T1M5; Q6DD85; Q9Y4D0"	"TYROBP causal network in microglia"	""	"1"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"2.5"	"0.0"	"7.7"	"9.4"	"50.4"	"98.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UHB9"	"Signal recognition particle subunit SRP68 OS=Homo sapiens OX=9606 GN=SRP68 PE=1 SV=2"	"0.000"	""	"6"	"3"	"5"	"3"	"627"	"70.7"	"8.56"	"589.65"	"10.03"	"2"	"3"	"transport;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf16969"	"6730"	"ENSG00000167881"	"SRP68"	"B3KUU5; B3KWY7; G3V1U4; hsa:6730; Q8NCJ4; Q8WUK2; Q9UHB9"	""	"SRP-dependent cotranslational protein targeting to membrane"	"1"	"0"	"103.2"	"81.1"	"112.6"	"122.5"	"103.4"	"71.4"	"151.7"	"227.9"	"214.1"	"574.7"	"1171.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00161"	"Synaptosomal-associated protein 23 OS=Homo sapiens OX=9606 GN=SNAP23 PE=1 SV=1"	"0.000"	""	"15"	"2"	"4"	"2"	"211"	"23.3"	"5.01"	"960.80"	"10.02"	"2"	"2"	"cell-cell signaling;cell organization and biogenesis;stress response;transport"	"plasma membrane;other membranes;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00835"	"8773"	"ENSG00000092531"	"SNAP23"	"hsa:8773; O00161; O00162; Q13602; Q6IAE3"	"Insulin signaling"	"RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; ER-Phagosome pathway; Translocation of SLC2A4 (GLUT4) to the plasma membrane; RAC3 GTPase cycle; RHOB GTPase cycle; RHOJ GTPase cycle; RHOF GTPase cycle; Neutrophil degranulation; trans-Golgi Network Vesicle Budding"	"13"	"0"	"100.3"	"89.8"	"116.1"	"95.7"	"91.6"	"103.6"	"114.0"	"184.1"	"187.9"	"382.2"	"570.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H974"	"Queuine tRNA-ribosyltransferase accessory subunit 2 OS=Homo sapiens OX=9606 GN=QTRT2 PE=1 SV=1"	"0.000"	""	"9"	"2"	"3"	"2"	"415"	"46.7"	"6.81"	"551.90"	"10.02"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"other membranes;mitochondrion;other cell component"	"other molecular function"	"Pf01702"	"79691"	"ENSG00000151576"	"QTRT2"	"A6NGE9; B7Z472; B7Z5R2; hsa:79691; J3KR78; Q6IA59; Q9H974"	""	"tRNA modification in the nucleus and cytosol"	"1"	"0"	"33.0"	"38.5"	"33.8"	"37.8"	"35.4"	"38.0"	"48.3"	"118.0"	"123.8"	"365.3"	"539.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O75528"	"Transcriptional adapter 3 OS=Homo sapiens OX=9606 GN=TADA3 PE=1 SV=1"	""	""	"6"	"1"	"2"	"1"	"432"	"48.9"	"6.27"	""	"10.01"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf10198"	"10474"	"ENSG00000171148"	"TADA3"	"hsa:10474; O75528; Q6FI83; Q9UFS2"	""	"Ub-specific processing proteases; Formation of WDR5-containing histone-modifying complexes; HATs acetylate histones"	"3"	"0"	"17.5"	"9.9"	"15.8"	"17.1"	"17.6"	"16.2"	"13.6"	"41.9"	"40.3"	"64.3"	"72.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H4L7"	"SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 OS=Homo sapiens OX=9606 GN=SMARCAD1 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"1026"	"117.3"	"5.55"	"1208.95"	"9.99"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271"	"56916"	"ENSG00000163104"	"SMARCAD1"	"B7Z799; hsa:56916; Q05D56; Q96SX1; Q9H017; Q9H4L7; Q9H860; Q9NPU9; Q9ULU7"	""	""	"0"	"0"	"147.0"	"94.5"	"150.8"	"146.3"	"130.0"	"130.6"	"152.4"	"229.0"	"218.9"	"468.0"	"717.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P24941"	"Cyclin-dependent kinase 2 OS=Homo sapiens OX=9606 GN=CDK2 PE=1 SV=2"	"0.000"	""	"16"	"4"	"7"	"3"	"298"	"33.9"	"8.68"	"1508.66"	"9.99"	"4"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"1017"	"ENSG00000123374"	"CDK2"	"A8K7C6; hsa:1017; O75100; P24941"	"miRNA regulation of DNA damage response; Cell cycle; Thyroid stimulating hormone (TSH) signaling pathway; Glioblastoma signaling pathways; Oncostatin M signaling pathway; Spinal cord injury; Retinoblastoma gene in cancer; Aryl hydrocarbon receptor pathway; Vitamin D receptor pathway; PI3K-Akt signaling pathway; G1 to S cell cycle control; Measles virus infection; Small cell lung cancer; DNA replication; p53 transcriptional gene network; Pleural mesothelioma; Sphingolipid metabolism in senescence; Urotensin-II-mediated signaling pathway; ID signaling pathway; TROP2 regulatory signaling; DNA damage response"	"TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; Regulation of TP53 Degradation; SCF(Skp2)-mediated degradation of p27/p21; Regulation of TP53 Activity through Phosphorylation; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; G2 Phase; Cyclin D associated events in G1; Defective binding of RB1 mutants to E2F1,(E2F2, E2F3); Telomere Extension By Telomerase; Regulation of APC/C activators between G1/S and early anaphase; Senescence-Associated Secretory Phenotype (SASP); Factors involved in megakaryocyte development and platelet production; Processing of DNA double-strand break ends; Cyclin A/B1/B2 associated events during G2/M transition; Meiotic recombination; DNA Damage/Telomere Stress Induced Senescence; Transcriptional regulation of granulopoiesis; G0 and Early G1; Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes; p53-Dependent G1 DNA Damage Response; PTK6 Regulates Cell Cycle"	"47"	"0"	"71.1"	"67.8"	"77.9"	"71.4"	"71.7"	"66.5"	"107.4"	"231.4"	"212.6"	"548.4"	"795.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12849"	"G-rich sequence factor 1 OS=Homo sapiens OX=9606 GN=GRSF1 PE=1 SV=3"	"0.000"	""	"9"	"3"	"5"	"3"	"480"	"53.1"	"6.19"	"643.83"	"9.91"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"2926"	"ENSG00000132463"	"GRSF1"	"B3KPW0; hsa:2926; Q12849; Q4W5S5; Q6ZST3; Q8IWD6; Q8NBD2"	"VEGFA-VEGFR2 signaling"	"Viral mRNA Translation"	"2"	"0"	"103.7"	"97.1"	"120.4"	"106.5"	"106.9"	"104.1"	"135.6"	"227.7"	"209.4"	"449.6"	"745.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62917"	"60S ribosomal protein L8 OS=Homo sapiens OX=9606 GN=RPL8 PE=1 SV=2"	"0.000"	""	"10"	"4"	"7"	"4"	"257"	"28.0"	"11.03"	"1241.18"	"9.90"	"4"	"3"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00181, Pf03947"	"6132"	"ENSG00000161016"	"RPL8"	"A8K094; D3DWN2; hsa:6132; P25120; P62917; Q567Q7; Q969V7; Q9BWQ9"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"528.6"	"439.6"	"580.2"	"502.0"	"502.1"	"554.4"	"754.6"	"1084.6"	"946.4"	"2249.7"	"3295.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HAJ7"	"Histone deacetylase complex subunit SAP30L OS=Homo sapiens OX=9606 GN=SAP30L PE=1 SV=1"	"0.000"	""	"17"	"3"	"6"	"3"	"183"	"20.9"	"9.36"	"1032.16"	"9.90"	"3"	"3"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf13866, Pf13867"	"79685"	"ENSG00000164576"	"SAP30L"	"E9PAU7; E9PAY2; hsa:79685; Q9HAJ7"	""	"Potential therapeutics for SARS; HDACs deacetylate histones; NoRC negatively regulates rRNA expression"	"3"	"0"	"87.7"	"52.5"	"88.5"	"76.9"	"90.0"	"69.5"	"114.5"	"279.1"	"263.0"	"785.2"	"1211.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5B9"	"FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1"	"0.000"	""	"3"	"3"	"6"	"3"	"1047"	"119.8"	"5.66"	"873.54"	"9.88"	"3"	"3"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus"	"other molecular function"	"Pf00557, Pf08512, Pf08644, Pf14826"	"11198"	"ENSG00000092201"	"SUPT16H"	"hsa:11198; Q6GMT8; Q6P2F1; Q6PJM1; Q9NRX0; Q9Y5B9"	""	"Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; Regulation of TP53 Activity through Phosphorylation"	"12"	"0"	"253.5"	"211.8"	"236.6"	"228.5"	"219.4"	"247.5"	"323.1"	"691.4"	"632.7"	"1748.4"	"2870.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12800"	"Alpha-globin transcription factor CP2 OS=Homo sapiens OX=9606 GN=TFCP2 PE=1 SV=2"	"0.000"	""	"4"	"2"	"6"	"2"	"502"	"57.2"	"5.80"	"941.24"	"9.88"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04516, Pf18016"	"7024"	"ENSG00000135457"	"TFCP2"	"A8K5E9; hsa:7024; Q12800; Q12801; Q9UD75; Q9UD77"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"181.1"	"158.0"	"204.5"	"168.4"	"168.0"	"197.2"	"284.7"	"1319.3"	"1329.4"	"3109.9"	"2904.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00186"	"Syntaxin-binding protein 3 OS=Homo sapiens OX=9606 GN=STXBP3 PE=1 SV=2"	"0.000"	""	"6"	"3"	"6"	"3"	"592"	"67.7"	"7.80"	"920.25"	"9.85"	"3"	"3"	"cell adhesion;cell-cell signaling;stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00995"	"6814"	"ENSG00000116266"	"STXBP3"	"A8K269; A8K5K7; hsa:6814; O00186; Q53FW1; Q86YJ3; Q9UPD7"	"Insulin signaling"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Disinhibition of SNARE formation"	"3"	"0"	"12.0"	"8.9"	"12.6"	"13.5"	"18.6"	"14.1"	"15.7"	"51.5"	"46.3"	"128.7"	"140.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09972"	"Fructose-bisphosphate aldolase C OS=Homo sapiens OX=9606 GN=ALDOC PE=1 SV=2"	"0.000"	""	"11"	"5"	"7"	"1"	"364"	"39.4"	"6.87"	"1196.69"	"9.83"	"4"	"3"	"other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00274"	"230"	"ENSG00000109107"	"ALDOC"	"B2R5R3; hsa:230; P09972; Q3SYL3; Q6FH94; Q6P0L5"	"Clear cell renal cell carcinoma pathways; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"Neutrophil degranulation; Glycolysis; Gluconeogenesis"	"6"	"0"	"18.8"	"9.1"	"18.5"	"19.0"	"23.1"	"18.2"	"19.5"	"50.4"	"45.6"	"129.0"	"162.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BY89"	"Uncharacterized protein KIAA1671 OS=Homo sapiens OX=9606 GN=KIAA1671 PE=1 SV=2"	"0.000"	""	"2"	"2"	"4"	"2"	"1806"	"196.6"	"8.47"	"1157.35"	"9.83"	"2"	"2"	""	""	""	"Pf15327"	"85379"	"ENSG00000197077"	"KIAA1671"	"B0QYF2; B7ZW08; hsa:85379; Q5THZ5; Q9BY89"	""	""	"0"	"0"	"68.4"	"62.9"	"56.0"	"64.8"	"53.5"	"64.1"	"77.9"	"104.7"	"104.2"	"197.3"	"271.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46109"	"Crk-like protein OS=Homo sapiens OX=9606 GN=CRKL PE=1 SV=1"	"0.000"	""	"13"	"3"	"5"	"3"	"303"	"33.8"	"6.74"	"709.08"	"9.82"	"2"	"3"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00017, Pf00018, Pf07653"	"1399"	"ENSG00000099942"	"CRKL"	"A8KA44; D3DX35; hsa:1399; P46109"	"Androgen receptor network in prostate cancer; B cell receptor signaling pathway; IL-3 signaling pathway; Kit receptor signaling pathway; Focal adhesion; Hepatocyte growth factor receptor signaling; MAPK signaling pathway; Chemokine signaling pathway; EGF/EGFR signaling pathway; 22q11.2 copy number variation syndrome; IL-2 signaling pathway; A network map of Macrophage-stimulating protein (MSP) signaling; Interferon type I signaling pathways; ErbB signaling pathway; T-cell receptor signaling pathway"	"Regulation of signaling by CBL; Downstream signal transduction; Erythropoietin activates RAS; Frs2-mediated activation; MET activates RAP1 and RAC1; MET receptor recycling"	"21"	"0"	"157.8"	"113.8"	"149.5"	"141.8"	"151.9"	"145.6"	"187.4"	"220.4"	"200.0"	"299.8"	"378.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BPW8"	"Protein NipSnap homolog 1 OS=Homo sapiens OX=9606 GN=NIPSNAP1 PE=1 SV=1"	"0.000"	""	"13"	"3"	"5"	"2"	"284"	"33.3"	"9.31"	"1354.75"	"9.82"	"3"	"2"	"other biological processes"	"plasma membrane;other membranes;mitochondrion"	"other molecular function"	"Pf07978"	"8508"	"ENSG00000184117"	"NIPSNAP1"	"B2RAY3; hsa:8508; O43800; Q9BPW8"	""	""	"0"	"0"	"44.4"	"32.5"	"40.4"	"44.5"	"51.8"	"39.6"	"50.5"	"109.9"	"92.0"	"253.8"	"346.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96DH6"	"RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1"	"0.000"	""	"11"	"2"	"3"	"2"	"328"	"35.2"	"8.48"	"333.04"	"9.81"	"1"	"2"	"developmental processes;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"124540"	"ENSG00000153944"	"MSI2"	"hsa:124540; Q7Z6M7; Q8N9T4; Q96DH6"	""	"RHOBTB2 GTPase cycle"	"1"	"0"	"175.6"	"158.6"	"159.3"	"181.5"	"160.4"	"139.3"	"205.0"	"267.3"	"234.1"	"414.6"	"571.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TEA8"	"D-aminoacyl-tRNA deacylase 1 OS=Homo sapiens OX=9606 GN=DTD1 PE=1 SV=2"	"0.000"	""	"13"	"3"	"6"	"3"	"209"	"23.4"	"8.24"	"1072.44"	"9.81"	"3"	"3"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02580"	"92675"	"ENSG00000125821"	"DTD1"	"A8K5X5; D3DW37; hsa:92675; Q496D1; Q5W184; Q8TEA8; Q8WXU8; Q9BW67; Q9H464; Q9H474"	""	""	"0"	"0"	"70.7"	"56.6"	"75.1"	"74.7"	"67.7"	"66.2"	"83.2"	"288.6"	"307.5"	"814.6"	"874.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A0FGR8"	"Extended synaptotagmin-2 OS=Homo sapiens OX=9606 GN=ESYT2 PE=1 SV=1"	"0.000"	""	"4"	"2"	"3"	"2"	"921"	"102.3"	"9.26"	"378.94"	"9.78"	"1"	"2"	"cell organization and biogenesis;transport"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00168, Pf17047"	"57488"	"ENSG00000117868"	"ESYT2"	"A0FGR8; A4D229; hsa:57488; Q69YJ2; Q6UKI4; Q6ZTU0; Q6ZVU1; Q9BQS0; Q9NW47; Q9ULJ2"	""	"Glycosphingolipid metabolism"	"1"	"0"	"31.4"	"21.8"	"38.7"	"48.0"	"60.3"	"106.5"	"189.1"	"284.2"	"272.8"	"291.9"	"262.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86VN1"	"Vacuolar protein-sorting-associated protein 36 OS=Homo sapiens OX=9606 GN=VPS36 PE=1 SV=1"	"0.000"	""	"8"	"3"	"6"	"3"	"386"	"43.8"	"7.20"	"1018.55"	"9.78"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport"	"other membranes;cytosol;nucleus;other cytoplasmic organelle"	"other molecular function"	"Pf04157, Pf11605"	"51028"	"ENSG00000136100"	"VPS36"	"A8K125; hsa:51028; Q3ZCV7; Q5H9S1; Q5VXB6; Q86VN1; Q9H8Z5; Q9Y3E3"	"Network map of SARS-CoV-2 signaling pathway"	"Endosomal Sorting Complex Required For Transport (ESCRT); HCMV Late Events"	"3"	"0"	"58.3"	"42.3"	"63.3"	"64.9"	"77.0"	"120.0"	"189.3"	"554.1"	"584.3"	"1262.7"	"1572.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P00374"	"Dihydrofolate reductase OS=Homo sapiens OX=9606 GN=DHFR PE=1 SV=2"	"0.000"	""	"27"	"4"	"6"	"4"	"187"	"21.4"	"7.42"	"1149.01"	"9.78"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00186"	"1719"	"ENSG00000228716"	"DHFR"	"B4DDD2; hsa:1719; P00374; Q14130; Q6IRW8"	"Fluoropyrimidine activity; Folate metabolism; One-carbon metabolism; Retinoblastoma gene in cancer; Trans-sulfuration, one-carbon metabolism and related pathways; Ethanol effects on histone modifications"	"G1/S-Specific Transcription; Metabolism of folate and pterines; Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"	"9"	"0"	"90.4"	"67.2"	"110.1"	"91.4"	"96.4"	"92.5"	"141.1"	"352.9"	"345.3"	"1025.7"	"1588.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55145"	"Mesencephalic astrocyte-derived neurotrophic factor OS=Homo sapiens OX=9606 GN=MANF PE=1 SV=3"	"0.000"	""	"21"	"5"	"8"	"5"	"182"	"20.7"	"8.69"	"2006.64"	"9.78"	"5"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf10208, Pf20145"	"7873"	"ENSG00000145050"	"MANF"	"hsa:7873; P55145; Q14CX4; Q86U67; Q96IS4"	"Orexin receptor pathway"	"Platelet degranulation"	"2"	"0"	"546.3"	"378.9"	"532.5"	"442.7"	"500.8"	"453.9"	"736.8"	"2346.9"	"2176.3"	"3191.1"	"2999.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3B4"	"Splicing factor 3B subunit 6 OS=Homo sapiens OX=9606 GN=SF3B6 PE=1 SV=1"	"0.000"	""	"18"	"2"	"6"	"2"	"125"	"14.6"	"9.38"	"960.92"	"9.78"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076"	"51639"	"ENSG00000115128"	"SF3B6"	"hsa:51639; Q53TM1; Q9Y3B4"	""	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"2"	"0"	"143.5"	"111.8"	"190.5"	"144.0"	"145.5"	"149.1"	"228.6"	"496.0"	"452.7"	"1407.9"	"2388.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96SB4"	"SRSF protein kinase 1 OS=Homo sapiens OX=9606 GN=SRPK1 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"655"	"74.3"	"6.16"	"896.86"	"9.78"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"6732"	"ENSG00000096063"	"SRPK1"	"B4DS61; hsa:6732; Q12890; Q5R364; Q5R365; Q8IY12; Q96SB4"	"VEGFA-VEGFR2 signaling; mRNA processing"	"Maturation of nucleoprotein"	"3"	"0"	"112.7"	"80.6"	"124.7"	"105.2"	"113.3"	"119.3"	"127.9"	"227.2"	"221.5"	"759.0"	"1271.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43242"	"26S proteasome non-ATPase regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PSMD3 PE=1 SV=2"	"0.000"	""	"7"	"2"	"3"	"2"	"534"	"60.9"	"8.44"	"344.85"	"9.75"	"1"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf01399, Pf08375"	"5709"	"ENSG00000108344"	"PSMD3"	"B3KMW9; B4DT72; hsa:5709; O43242; Q96EI2; Q9BQA4"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"64"	"0"	"13.6"	"16.6"	"24.1"	"19.8"	"21.9"	"22.7"	"24.5"	"36.1"	"41.9"	"93.6"	"187.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16881"	"Thioredoxin reductase 1, cytoplasmic OS=Homo sapiens OX=9606 GN=TXNRD1 PE=1 SV=3"	"0.000"	""	"6"	"2"	"3"	"2"	"649"	"70.9"	"7.39"	"326.60"	"9.75"	"1"	"2"	"cell cycle OR cell proliferation;developmental processes;signal transduction;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00462, Pf02852, Pf07992"	"7296"	"ENSG00000198431"	"TXNRD1"	"B7Z1F4; B7Z3Y8; B7Z904; E9PMY9; F5H780; hsa:7296; Q16881; Q6FI31; Q6VB40; Q6VB41; Q6VB42; Q6VBP2; Q6VBP3; Q6VBP4; Q6VBP5; Q6VBP9; Q6VBQ0; Q6YNQ1; Q76P53; Q7LA96; Q8WVC8; Q99475; Q9UES8; Q9UH79"	"Selenium micronutrient network; Selenium micronutrient network ; Selenium micronutrient network; Nuclear receptors meta-pathway; NRF2 pathway; Oxidative stress response; Ferroptosis"	"PPARA activates gene expression; NFE2L2 regulating anti-oxidant/detoxification enzymes; Detoxification of Reactive Oxygen Species; TP53 Regulates Metabolic Genes; Interconversion of nucleotide di- and triphosphates; Metabolism of ingested H2SeO4 and H2SeO3 into H2Se; Uptake and function of diphtheria toxin; Metabolism of ingested MeSeO2H into MeSeH"	"15"	"0"	"10.7"	"11.7"	"17.8"	"19.2"	"16.9"	"13.5"	"23.5"	"49.3"	"60.6"	"223.4"	"343.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13442"	"28 kDa heat- and acid-stable phosphoprotein OS=Homo sapiens OX=9606 GN=PDAP1 PE=1 SV=1"	"0.000"	""	"23"	"5"	"8"	"5"	"181"	"20.6"	"8.87"	"1991.03"	"9.74"	"5"	"3"	"signal transduction"	"non-structural extracellular;plasma membrane;other membranes;cytosol;other cell component"	""	"Pf10252"	"11333"	"ENSG00000106244"	"PDAP1"	"D6W5S5; hsa:11333; Q13442; Q92906"	""	"Neutrophil degranulation"	"1"	"0"	"541.1"	"414.4"	"493.6"	"461.7"	"490.9"	"492.6"	"622.8"	"1287.3"	"1218.4"	"1766.2"	"1782.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7RTV0"	"PHD finger-like domain-containing protein 5A OS=Homo sapiens OX=9606 GN=PHF5A PE=1 SV=1"	"0.000"	""	"27"	"3"	"5"	"3"	"110"	"12.4"	"8.41"	"622.59"	"9.74"	"2"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03660"	"84844"	"ENSG00000100410"	"PHF5A"	"hsa:84844; Q7RTV0; Q9UH06"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"704.4"	"596.6"	"671.2"	"619.9"	"604.6"	"548.6"	"781.2"	"940.9"	"827.9"	"1724.5"	"2706.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19793"	"Retinoic acid receptor RXR-alpha OS=Homo sapiens OX=9606 GN=RXRA PE=1 SV=1"	"0.000"	""	"7"	"2"	"4"	"2"	"462"	"50.8"	"7.80"	"280.98"	"9.73"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00104, Pf00105, Pf11825"	"6256"	"ENSG00000186350"	"RXRA"	"B3KY83; hsa:6256; P19793; Q2NL52; Q2V504"	"Vitamin D metabolism; Energy metabolism; Nuclear receptors; Adipogenesis; Liver X receptor pathway; Constitutive androstane receptor pathway; Pregnane X receptor pathway; Vitamin D receptor pathway; PPAR-alpha pathway; Farnesoid X receptor pathway; Glucocorticoid receptor pathway; Nuclear receptors meta-pathway; NRF2 pathway; Transcription factor regulation in adipogenesis; Angiopoietin-like protein 8 regulatory pathway; PPAR signaling pathway; Prion disease pathway; PI3K/AKT/mTOR - vitamin D3 signaling; Non-small cell lung cancer; Non-genomic actions of 1,25 dihydroxyvitamin D3; Vitamins A and D - action mechanisms; Nonalcoholic fatty liver disease; Vitamin D in inflammatory diseases; Small cell lung cancer; Vitamin D-sensitive calcium signaling in depression; Thyroid hormones production and peripheral downstream signaling effects; Antiviral and anti-inflammatory effects of Nrf2 on SARS-CoV-2 pathway; Th17 cell differentiation pathway; Kleefstra syndrome; Vitamin A1 and A5/X pathways; Vitamin A and carotenoid metabolism"	"Activation of anterior HOX genes in hindbrain development during early embryogenesis; NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux; Transcriptional activation of mitochondrial biogenesis; PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; Endogenous sterols; Heme signaling; BMAL1:CLOCK,NPAS2 activates circadian gene expression; Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid; Nuclear Receptor transcription pathway; SUMOylation of intracellular receptors; Cytoprotection by HMOX1; Carnitine metabolism; Activation of gene expression by SREBF (SREBP); NR1H2 & NR1H3 regulate gene expression linked to lipogenesis; Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol; Recycling of bile acids and salts; NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose; Transcriptional regulation of granulopoiesis; RORA activates gene expression; NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis; Synthesis of bile acids and bile salts via 27-hydroxycholesterol; NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake ; NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis"	"59"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96KR1"	"Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2"	"0.000"	""	"3"	"3"	"6"	"3"	"1074"	"116.9"	"9.04"	"1257.15"	"9.72"	"3"	"3"	""	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf07528, Pf12874"	"51663"	"ENSG00000056097"	"ZFR"	"B2RNR5; hsa:51663; Q05C08; Q3B7X5; Q6P5A3; Q86UA0; Q96KR1; Q9H6V4; Q9NTI1; Q9Y687"	"Exercise-induced circadian regulation"	""	"1"	"0"	"321.5"	"252.5"	"316.0"	"280.1"	"295.8"	"304.7"	"378.2"	"353.2"	"374.0"	"511.2"	"703.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95239"	"Chromosome-associated kinesin KIF4A OS=Homo sapiens OX=9606 GN=KIF4A PE=1 SV=3"	"0.000"	""	"4"	"4"	"6"	"4"	"1232"	"139.8"	"6.27"	"1052.92"	"9.72"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00225"	"24137"	"ENSG00000090889"	"KIF4A"	"B2R7V5; D3DVU4; hsa:24137; O95239; Q86TN3; Q86XX7; Q9NNY6; Q9NY24; Q9UMW3"	"Retinoblastoma gene in cancer"	"Recycling pathway of L1; COPI-dependent Golgi-to-ER retrograde traffic; MHC class II antigen presentation; Kinesins"	"5"	"0"	"87.7"	"66.7"	"90.7"	"66.1"	"94.6"	"75.2"	"96.0"	"216.2"	"230.8"	"442.3"	"613.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96J02"	"E3 ubiquitin-protein ligase Itchy homolog OS=Homo sapiens OX=9606 GN=ITCH PE=1 SV=2"	"0.000"	""	"4"	"3"	"5"	"3"	"903"	"102.7"	"6.30"	"672.87"	"9.67"	"2"	"3"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00168, Pf00397, Pf00632"	"83737"	"ENSG00000078747"	"ITCH"	"A6NEW4; B4E234; E1P5P3; F5H217; hsa:83737; O43584; Q5QP37; Q5TEL0; Q96F66; Q96J02; Q9BY75; Q9H451; Q9H4U5"	"VEGFA-VEGFR2 signaling; EGF/EGFR signaling pathway; Nonalcoholic fatty liver disease; 10q11.21q11.23 copy number variation syndrome; Notch signaling pathway"	"Antigen processing: Ubiquitination & Proteasome degradation; Degradation of GLI1 by the proteasome; Hedgehog 'on' state; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Activated NOTCH1 Transmits Signal to the Nucleus; Regulation of necroptotic cell death; NOD1/2 Signaling Pathway; Negative regulators of DDX58/IFIH1 signaling; SARS-CoV-1 activates/modulates innate immune responses; Downregulation of ERBB4 signaling"	"15"	"0"	"77.4"	"40.0"	"77.3"	"57.8"	"77.7"	"71.7"	"89.4"	"250.1"	"255.6"	"879.4"	"1158.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H5V9"	"UPF0428 protein CXorf56 OS=Homo sapiens OX=9606 GN=CXorf56 PE=1 SV=1"	"0.000"	""	"14"	"3"	"6"	"3"	"222"	"25.6"	"8.73"	"968.20"	"9.67"	"3"	"2"	"cell organization and biogenesis;transport"	"cytoskeleton;nucleus;other cell component"	""	""	"63932"	"ENSG00000018610"	"STEEP1"	"A8MPX7; B4DQN2; D3DWH9; F5GWL7; hsa:63932; O43351; Q9H5V9"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"517.1"	"408.9"	"496.0"	"442.8"	"467.5"	"422.9"	"576.4"	"808.8"	"739.0"	"1304.1"	"1351.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09234"	"U1 small nuclear ribonucleoprotein C OS=Homo sapiens OX=9606 GN=SNRPC PE=1 SV=1"	"0.000"	""	"13"	"2"	"5"	"2"	"159"	"17.4"	"9.67"	"805.39"	"9.67"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf06220"	"6631"	"ENSG00000124562"	"SNRPC"	"hsa:6631; P09234; Q5TAL3"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"353.6"	"166.2"	"344.7"	"298.7"	"273.9"	"280.9"	"380.7"	"572.4"	"525.2"	"1049.7"	"2291.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92797"	"Symplekin OS=Homo sapiens OX=9606 GN=SYMPK PE=1 SV=2"	"0.000"	""	"4"	"2"	"3"	"2"	"1274"	"141.1"	"6.13"	"476.41"	"9.64"	"1"	"2"	"cell adhesion;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	""	"Pf11935, Pf12295"	"8189"	"ENSG00000125755"	"SYMPK"	"hsa:8189; O00521; O00689; O00733; Q59GT5; Q8N2U5; Q92797"	""	"Transport of Mature mRNA Derived from an Intronless Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"5"	"0"	"50.9"	"41.1"	"58.5"	"50.8"	"53.5"	"48.6"	"60.8"	"136.8"	"124.0"	"326.2"	"444.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NWU1"	"3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial OS=Homo sapiens OX=9606 GN=OXSM PE=1 SV=1"	"0.000"	""	"8"	"2"	"3"	"2"	"459"	"48.8"	"7.66"	"380.50"	"9.64"	"1"	"2"	"other metabolic processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf00109, Pf02801"	"54995"	"ENSG00000151093"	"OXSM"	"hsa:54995; Q9NWU1"	"Mitochondrial fatty acid synthesis pathway"	""	"1"	"0"	"100.2"	"91.6"	"93.0"	"87.5"	"72.6"	"101.1"	"137.9"	"260.7"	"289.9"	"558.5"	"834.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P12277"	"Creatine kinase B-type OS=Homo sapiens OX=9606 GN=CKB PE=1 SV=1"	"0.000"	""	"12"	"3"	"5"	"3"	"381"	"42.6"	"5.59"	"735.99"	"9.63"	"2"	"3"	"other metabolic processes;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00217, Pf02807"	"1152"	"ENSG00000166165"	"CKB"	"A8K236; B2R5R4; hsa:1152; P12277; Q2LE07; Q6FG40; Q9UC66"	""	"RND3 GTPase cycle; Creatine metabolism"	"2"	"0"	"172.3"	"134.7"	"194.8"	"176.8"	"145.7"	"133.2"	"174.2"	"257.4"	"245.5"	"399.6"	"544.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22415"	"Upstream stimulatory factor 1 OS=Homo sapiens OX=9606 GN=USF1 PE=1 SV=1"	"0.000"	""	"12"	"2"	"3"	"1"	"310"	"33.5"	"5.54"	"270.37"	"9.63"	"1"	"2"	"stress response;other biological processes"	"ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00010"	"7391"	"ENSG00000158773"	"USF1"	"B2RBZ4; hsa:7391; P22415; Q5SY46; Q7Z5Y1"	"7q11.23 copy number variation syndrome; Familial hyperlipidemia type 2"	"Estrogen-dependent gene expression"	"3"	"0"	"21.2"	"21.7"	"33.4"	"35.1"	"27.2"	"28.0"	"36.9"	"98.0"	"95.3"	"219.6"	"276.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P21796"	"Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2"	"0.000"	""	"12"	"3"	"5"	"3"	"283"	"30.8"	"8.54"	"816.08"	"9.62"	"2"	"3"	"cell-cell signaling;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;mitochondrion;other cell component"	"transporter activity;other molecular function"	"Pf01459"	"7416"	"ENSG00000213585"	"VDAC1"	"B3KVK4; D3DQ93; hsa:7416; P21796; Q5FVE7; Q9UIQ5; Q9UPL0"	"Alzheimer's disease and miRNA effects; Alzheimer's disease; Arsenic metabolism and reactive oxygen species generation; Cholesterol metabolism; Fatty Acids and Lipoproteins Transport in Hepatocytes"	"Ub-specific processing proteases; Pyruvate metabolism; Mitochondrial protein import; PINK1-PRKN Mediated Mitophagy; Mitochondrial calcium ion transport"	"10"	"0"	"51.8"	"38.6"	"66.9"	"52.0"	"44.0"	"56.2"	"62.1"	"177.8"	"185.6"	"501.0"	"711.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75380"	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS6 PE=1 SV=1"	"0.000"	""	"21"	"2"	"4"	"2"	"124"	"13.7"	"8.28"	"1135.59"	"9.61"	"2"	"2"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf10276"	"4726"	"ENSG00000145494"	"NDUFS6"	"hsa:4726; O75380"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"79.7"	"79.1"	"86.8"	"91.5"	"85.8"	"92.3"	"103.0"	"184.4"	"193.7"	"417.6"	"508.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62906"	"60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2"	"0.000"	""	"15"	"3"	"6"	"3"	"217"	"24.8"	"9.94"	"1183.23"	"9.61"	"3"	"3"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf00687"	"4736"	"ENSG00000198755"	"RPL10A"	"B2R801; hsa:4736; P52859; P53025; P62906; Q5TZT6; Q8J013"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; SRP-dependent cotranslational protein targeting to membrane; Selenocysteine synthesis; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"15"	"0"	"214.1"	"156.0"	"258.0"	"185.7"	"197.8"	"206.7"	"293.0"	"490.2"	"483.1"	"1147.9"	"1869.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15651"	"High mobility group nucleosome-binding domain-containing protein 3 OS=Homo sapiens OX=9606 GN=HMGN3 PE=1 SV=2"	"0.000"	""	"42"	"3"	"5"	"3"	"99"	"10.7"	"9.66"	"859.22"	"9.61"	"2"	"3"	"cell organization and biogenesis"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01101"	"9324"	"ENSG00000118418"	"HMGN3"	"B2RD37; hsa:9324; Q15651; Q5HYD3; Q7RTT0; Q969M5; Q9BZT7"	""	""	"0"	"0"	"193.9"	"156.9"	"175.1"	"175.1"	"177.2"	"166.5"	"225.2"	"266.8"	"269.2"	"325.8"	"301.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P41240"	"Tyrosine-protein kinase CSK OS=Homo sapiens OX=9606 GN=CSK PE=1 SV=1"	"0.000"	""	"8"	"3"	"6"	"3"	"450"	"50.7"	"7.06"	"1009.80"	"9.58"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00017, Pf00018, Pf07714"	"1445"	"ENSG00000103653"	"CSK"	"hsa:1445; P41240; Q2M3N2; Q6FGZ6"	"Integrin-mediated cell adhesion; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; EGF/EGFR signaling pathway; Regulation of actin cytoskeleton"	"Phosphorylation of CD3 and TCR zeta chains; PD-1 signaling; Signaling by BRAF and RAF1 fusions; Negative regulation of FLT3; GAB1 signalosome; Integrin signaling; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; RHOH GTPase cycle; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants"	"18"	"0"	"14.2"	"12.5"	"17.8"	"17.7"	"19.2"	"13.5"	"25.0"	"47.2"	"55.4"	"178.1"	"331.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23919"	"Thymidylate kinase OS=Homo sapiens OX=9606 GN=DTYMK PE=1 SV=4"	"0.000"	""	"11"	"3"	"6"	"3"	"212"	"23.8"	"8.27"	"1195.76"	"9.57"	"3"	"3"	"other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf02223"	"1841"	"ENSG00000168393"	"DTYMK"	"B7ZW70; hsa:1841; P23919; Q6FGX1; Q9BUX4"	"Pyrimidine metabolism; 2q37 copy number variation syndrome"	"Interconversion of nucleotide di- and triphosphates"	"3"	"0"	"68.9"	"49.9"	"60.5"	"58.1"	"55.4"	"62.4"	"80.4"	"142.9"	"140.1"	"375.5"	"499.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IZP0"	"Abl interactor 1 OS=Homo sapiens OX=9606 GN=ABI1 PE=1 SV=4"	"0.000"	""	"7"	"2"	"4"	"2"	"508"	"55.0"	"7.06"	"1169.74"	"9.57"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00018, Pf07815"	"10006"	"ENSG00000136754"	"ABI1"	"A9Z1Y6; B3KX62; B4DQ58; H7BXI6; hsa:10006; O15147; O76049; O95060; Q5T2R3; Q5T2R4; Q5T2R6; Q5T2R7; Q5T2R9; Q5W070; Q5W072; Q8IZP0; Q8TB63; Q96S81; Q9NXZ9; Q9NYB8"	"EGF/EGFR signaling pathway"	"Regulation of actin dynamics for phagocytic cup formation; VEGFA-VEGFR2 Pathway; FCGR3A-mediated phagocytosis; RAC1 GTPase cycle; RHO GTPases Activate WASPs and WAVEs; RAC2 GTPase cycle; RAC3 GTPase cycle"	"8"	"0"	"76.4"	"66.0"	"71.3"	"73.1"	"69.0"	"71.1"	"89.9"	"149.3"	"140.2"	"224.7"	"274.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NX63"	"MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1"	"0.000"	""	"9"	"3"	"6"	"3"	"227"	"26.1"	"8.28"	"1060.57"	"9.56"	"3"	"3"	"cell organization and biogenesis"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf05300"	"54927"	"ENSG00000106554"	"CHCHD3"	"hsa:54927; Q9NX63"	""	"Mitochondrial protein import; Cristae formation"	"2"	"0"	"178.2"	"122.0"	"171.9"	"136.3"	"166.9"	"160.0"	"221.3"	"563.6"	"531.7"	"1584.5"	"2350.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16698"	"2,4-dienoyl-CoA reductase, mitochondrial OS=Homo sapiens OX=9606 GN=DECR1 PE=1 SV=1"	"0.000"	""	"10"	"2"	"3"	"2"	"335"	"36.0"	"9.28"	"507.21"	"9.56"	"1"	"2"	"other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf13561"	"1666"	"ENSG00000104325"	"DECR1"	"B7Z6B8; hsa:1666; Q16698; Q2M304; Q93085"	"Fatty acid beta-oxidation; Fatty acid biosynthesis; VEGFA-VEGFR2 signaling"	"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids"	"4"	"0"	"52.7"	"52.3"	"60.4"	"56.3"	"52.1"	"63.2"	"82.8"	"203.7"	"238.9"	"547.6"	"832.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92769"	"Histone deacetylase 2 OS=Homo sapiens OX=9606 GN=HDAC2 PE=1 SV=2"	"0.000"	""	"9"	"3"	"6"	"3"	"488"	"55.3"	"5.91"	"1187.23"	"9.56"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00850"	"3066"	"ENSG00000196591"	"HDAC2"	"B3KRS5; B4DL58; E1P561; hsa:3066; Q5SRI8; Q5SZ86; Q8NEH4; Q92769"	"Cell cycle; Neural crest differentiation; Notch signaling; Initiation of transcription and translation elongation at the HIV-1 LTR; Ethanol effects on histone modifications; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; Ciliary landscape; 7q11.23 copy number variation syndrome; SARS-CoV-2 innate immunity evasion and cell-specific immune response; TAR syndrome; Notch signaling pathway"	"Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; NOTCH1 Intracellular Domain Regulates Transcription; NoRC negatively regulates rRNA expression; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; RNA Polymerase I Transcription Initiation; Regulation of TP53 Activity through Acetylation; Potential therapeutics for SARS; SUMOylation of chromatin organization proteins; HDACs deacetylate histones; FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes; Regulation of PTEN gene transcription; Factors involved in megakaryocyte development and platelet production; p75NTR negatively regulates cell cycle via SC1; Notch-HLH transcription pathway; Regulation of MECP2 expression and activity; STAT3 nuclear events downstream of ALK signaling; EGR2 and SOX10-mediated initiation of Schwann cell myelination; MECP2 regulates neuronal receptors and channels"	"30"	"0"	"237.6"	"200.4"	"210.4"	"209.4"	"202.3"	"220.9"	"241.8"	"375.5"	"365.8"	"866.0"	"1373.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42566"	"Epidermal growth factor receptor substrate 15 OS=Homo sapiens OX=9606 GN=EPS15 PE=1 SV=2"	"0.000"	""	"5"	"4"	"7"	"4"	"896"	"98.6"	"4.64"	"1307.41"	"9.52"	"4"	"3"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	""	"2060"	"ENSG00000085832"	"EPS15"	"B2R8J7; D3DPJ2; hsa:2060; P42566; Q5SRH4"	"VEGFA-VEGFR2 signaling; Ebola virus infection in host; EGF/EGFR signaling pathway"	"Cargo recognition for clathrin-mediated endocytosis; EGFR downregulation; Negative regulation of MET activity; InlB-mediated entry of Listeria monocytogenes into host cell"	"8"	"0"	"118.6"	"105.9"	"110.4"	"113.6"	"102.3"	"113.7"	"180.6"	"371.7"	"404.6"	"664.8"	"662.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3T9"	"Nucleolar complex protein 2 homolog OS=Homo sapiens OX=9606 GN=NOC2L PE=1 SV=4"	"0.000"	""	"6"	"4"	"7"	"4"	"749"	"84.9"	"5.62"	"1329.70"	"9.51"	"4"	"3"	"cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf03715"	"26155"	"ENSG00000188976"	"NOC2L"	"hsa:26155; Q5SVA3; Q9BTN6; Q9Y3T9"	"1p36 copy number variation syndrome"	"Regulation of TP53 Activity through Phosphorylation"	"2"	"0"	"289.3"	"260.9"	"282.5"	"268.5"	"232.8"	"278.1"	"314.9"	"414.0"	"405.7"	"741.9"	"973.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13825"	"Methylglutaconyl-CoA hydratase, mitochondrial OS=Homo sapiens OX=9606 GN=AUH PE=1 SV=1"	"0.000"	""	"10"	"3"	"6"	"3"	"339"	"35.6"	"9.48"	"1136.48"	"9.50"	"3"	"3"	"other metabolic processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00378"	"549"	"ENSG00000148090"	"AUH"	"B1ALV7; B1ALV8; hsa:549; Q13825; Q8WUE4"	"Amino acid metabolism"	"Branched-chain amino acid catabolism"	"2"	"0"	"277.3"	"237.0"	"290.6"	"242.5"	"272.0"	"288.1"	"369.1"	"269.8"	"237.4"	"308.1"	"446.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y608"	"Leucine-rich repeat flightless-interacting protein 2 OS=Homo sapiens OX=9606 GN=LRRFIP2 PE=1 SV=1"	"0.000"	""	"4"	"2"	"4"	"2"	"721"	"82.1"	"6.95"	"908.36"	"9.50"	"2"	"2"	"cell-cell signaling;signal transduction;other biological processes"	""	"other molecular function"	"Pf09738"	"9209"	"ENSG00000093167"	"LRRFIP2"	"A8K649; A8MXR0; B4DY63; hsa:9209; Q68CV3; Q9NXH5; Q9Y608"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"15.6"	"6.9"	"11.2"	"12.3"	"6.4"	"8.7"	"14.5"	"45.8"	"49.0"	"169.6"	"287.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IYB8"	"ATP-dependent RNA helicase SUPV3L1, mitochondrial OS=Homo sapiens OX=9606 GN=SUPV3L1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"4"	"1"	"786"	"87.9"	"7.99"	"874.08"	"9.50"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cytoplasmic organelle"	"nucleic acid binding activity;other molecular function"	"Pf00271, Pf12513, Pf18114, Pf18147"	"6832"	"ENSG00000156502"	"SUPV3L1"	"A8K301; hsa:6832; O43630; Q8IYB8"	""	""	"0"	"0"	"140.2"	"128.7"	"122.5"	"128.8"	"146.5"	"133.6"	"167.0"	"219.5"	"226.0"	"318.4"	"379.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TEM1"	"Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3"	"0.000"	""	"2"	"4"	"7"	"4"	"1887"	"205.0"	"6.81"	"1330.82"	"9.49"	"4"	"3"	"transport"	"other membranes;ER/Golgi;nucleus"	""	"Pf02368"	"23225"	"ENSG00000132182"	"NUP210"	"A6NN56; hsa:23225; O94980; Q6NXG6; Q8NBJ1; Q8TEM1; Q9H6C8; Q9UFP3"	""	"ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; snRNP Assembly; HCMV Late Events; HCMV Early Events; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"28"	"0"	"76.4"	"54.3"	"68.0"	"64.4"	"62.7"	"69.0"	"84.3"	"184.3"	"185.5"	"669.2"	"1084.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5D862"	"Filaggrin-2 OS=Homo sapiens OX=9606 GN=FLG2 PE=1 SV=1"	"0.000"	""	"1"	"2"	"6"	"2"	"2391"	"247.9"	"8.31"	"861.18"	"9.49"	"2"	"2"	"cell adhesion;other biological processes"	"non-structural extracellular;plasma membrane;other cell component"	"other molecular function"	"Pf01023"	"388698"	"ENSG00000143520"	"FLG2"	"hsa:388698; Q5D862; Q9H4U1"	""	"Neutrophil degranulation"	"1"	"0"	"36.4"	"44.2"	"245.4"	"88.4"	"103.1"	"39.4"	"48.2"	"167.0"	"232.2"	"270.8"	"257.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15427"	"Splicing factor 3B subunit 4 OS=Homo sapiens OX=9606 GN=SF3B4 PE=1 SV=1"	"0.000"	""	"10"	"3"	"5"	"3"	"424"	"44.4"	"8.56"	"529.42"	"9.48"	"2"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00076"	"10262"	"ENSG00000143368"	"SF3B4"	"hsa:10262; Q15427; Q5SZ63"	"mRNA processing; 10q22q23 copy number variation"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"4"	"0"	"414.2"	"400.4"	"376.7"	"338.6"	"378.4"	"356.8"	"484.4"	"590.3"	"537.3"	"1173.0"	"1792.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HD33"	"39S ribosomal protein L47, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL47 PE=1 SV=2"	"0.000"	""	"11"	"3"	"5"	"3"	"250"	"29.4"	"10.37"	"613.52"	"9.46"	"2"	"3"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf06984"	"57129"	"ENSG00000136522"	"MRPL47"	"hsa:57129; Q6XRG1; Q8N5D1; Q9HD33"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"62.1"	"35.1"	"69.1"	"60.0"	"58.5"	"55.1"	"94.2"	"147.3"	"169.5"	"372.6"	"637.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BQP7"	"Mitochondrial genome maintenance exonuclease 1 OS=Homo sapiens OX=9606 GN=MGME1 PE=1 SV=1"	"0.000"	""	"9"	"3"	"5"	"3"	"344"	"39.4"	"7.68"	"772.52"	"9.40"	"2"	"3"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response"	"mitochondrion"	"other molecular function"	"Pf12705"	"92667"	"ENSG00000125871"	"MGME1"	"B2RDG5; D3DW29; hsa:92667; Q96SW3; Q9BQP7"	"Primary ovarian insufficiency"	""	"1"	"0"	"51.0"	"32.5"	"55.6"	"50.1"	"53.0"	"46.4"	"59.2"	"235.6"	"256.7"	"699.4"	"1062.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BWS9"	"Chitinase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHID1 PE=1 SV=1"	"0.000"	""	"6"	"3"	"6"	"3"	"393"	"44.9"	"8.63"	"1003.15"	"9.39"	"3"	"3"	"other metabolic processes;stress response;other biological processes"	"non-structural extracellular;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00704"	"66005"	"ENSG00000177830"	"CHID1"	"B3KWB0; hsa:66005; Q8NBM9; Q96CZ3; Q96S93; Q96SK0; Q9BWS9; Q9BY52"	""	"Platelet degranulation"	"1"	"0"	"539.4"	"473.6"	"424.6"	"396.0"	"427.9"	"437.5"	"573.6"	"790.7"	"674.9"	"902.9"	"1027.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00255"	"Menin OS=Homo sapiens OX=9606 GN=MEN1 PE=1 SV=4"	"0.000"	""	"8"	"4"	"6"	"4"	"615"	"68.0"	"6.55"	"1006.93"	"9.36"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05053"	"4221"	"ENSG00000133895"	"MEN1"	"A5HBC6; A5HBC7; A5HBC8; A5HBC9; A5HBD0; A5HBD1; A5HBD2; hsa:4221; O00255; O00632; Q9BUF0; Q9BUK2"	"10q11.21q11.23 copy number variation syndrome"	"RHO GTPases activate IQGAPs; Formation of WDR5-containing histone-modifying complexes; Formation of the beta-catenin:TCF transactivating complex; SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Deactivation of the beta-catenin transactivating complex; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation"	"8"	"0"	"273.4"	"144.9"	"316.1"	"240.0"	"242.8"	"244.1"	"286.8"	"400.0"	"427.2"	"788.2"	"924.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86TU7"	"Actin-histidine N-methyltransferase OS=Homo sapiens OX=9606 GN=SETD3 PE=1 SV=1"	"0.000"	""	"7"	"3"	"5"	"3"	"594"	"67.2"	"5.96"	"1073.67"	"9.35"	"3"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00856, Pf09273"	"84193"	"ENSG00000183576"	"SETD3"	"A0PJU3; A5PLP0; B4DZE8; hsa:84193; Q0VAQ2; Q659C0; Q86TU7; Q86TU8; Q96GY9; Q9H5U5"	"Histone modifications"	"PKMTs methylate histone lysines"	"2"	"0"	"66.9"	"64.0"	"76.6"	"65.4"	"68.8"	"60.3"	"99.9"	"403.1"	"391.6"	"1133.4"	"1245.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BVG4"	"Protein PBDC1 OS=Homo sapiens OX=9606 GN=PBDC1 PE=1 SV=1"	"0.000"	""	"16"	"3"	"6"	"3"	"233"	"26.0"	"4.79"	"982.14"	"9.35"	"3"	"3"	""	""	""	"Pf04669"	"51260"	"ENSG00000102390"	"PBDC1"	"hsa:51260; Q9BVG4"	""	""	"0"	"0"	"98.9"	"71.0"	"116.4"	"111.5"	"93.2"	"100.2"	"127.2"	"316.3"	"322.3"	"751.5"	"921.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22570"	"NADPH:adrenodoxin oxidoreductase, mitochondrial OS=Homo sapiens OX=9606 GN=FDXR PE=1 SV=3"	"0.000"	""	"8"	"3"	"5"	"3"	"491"	"53.8"	"8.44"	"565.11"	"9.35"	"2"	"3"	"other metabolic processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf07992"	"2232"	"ENSG00000161513"	"FDXR"	"B4DDI7; B4DHX5; B4DQQ4; B4DX24; B7Z7G2; E7EQC1; hsa:2232; P22570; Q13716; Q4PJI0; Q9BU12"	"Iron-sulfur cluster biogenesis"	"Endogenous sterols; Pregnenolone biosynthesis; Defective CYP11A1 causes AICSR; Electron transport from NADPH to Ferredoxin"	"5"	"0"	"75.7"	"51.8"	"73.6"	"77.4"	"63.6"	"75.2"	"99.6"	"223.1"	"305.1"	"693.3"	"999.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q03188"	"Centromere protein C OS=Homo sapiens OX=9606 GN=CENPC PE=1 SV=2"	"0.000"	""	"5"	"3"	"5"	"3"	"943"	"106.8"	"9.39"	"609.54"	"9.34"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf11699, Pf15620, Pf15622"	"1060"	"ENSG00000145241"	"CENPC"	"hsa:1060; Q03188; Q6PIR0; Q8IW27; Q9P0M5"	""	"Separation of Sister Chromatids; Deposition of new CENPA-containing nucleosomes at the centromere; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"7"	"0"	"73.8"	"55.6"	"63.0"	"59.8"	"71.2"	"71.8"	"86.3"	"165.5"	"157.1"	"272.4"	"333.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NFH5"	"Nucleoporin NUP35 OS=Homo sapiens OX=9606 GN=NUP35 PE=1 SV=1"	"0.000"	""	"13"	"3"	"5"	"3"	"326"	"34.8"	"9.09"	"1104.88"	"9.33"	"3"	"2"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf05172"	"129401"	"ENSG00000163002"	"NUP35"	"B4DP57; B4DYB4; hsa:129401; Q4ZFZ9; Q53S95; Q8NFH5; Q8TDJ1"	""	"SARS-CoV-2 activates/modulates innate and adaptive immune responses; HCMV Early Events; ISG15 antiviral mechanism; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; HCMV Late Events; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; Postmitotic nuclear pore complex (NPC) reformation"	"29"	"0"	"316.5"	"242.3"	"284.0"	"281.7"	"265.4"	"261.7"	"325.9"	"427.1"	"405.5"	"838.1"	"1125.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14974"	"Protein phosphatase 1 regulatory subunit 12A OS=Homo sapiens OX=9606 GN=PPP1R12A PE=1 SV=1"	"0.000"	""	"4"	"3"	"4"	"3"	"1030"	"115.2"	"5.40"	"303.13"	"9.33"	"1"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00023, Pf15898"	"4659"	"ENSG00000058272"	"PPP1R12A"	"B4DZ09; F8VWB4; hsa:4659; O14974; Q2NKL4; Q569H0; Q86WU3; Q8NFR6; Q9BYH0"	"Focal adhesion; Hippo-Merlin signaling dysregulation; Regulation of actin cytoskeleton"	"Regulation of PLK1 Activity at G2/M Transition; RHO GTPases activate CIT; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; RHO GTPases activate PAKs"	"8"	"0"	"121.8"	"100.6"	"113.5"	"109.7"	"98.5"	"98.5"	"153.1"	"238.7"	"190.4"	"447.4"	"579.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WWI1"	"LIM domain only protein 7 OS=Homo sapiens OX=9606 GN=LMO7 PE=1 SV=3"	"0.000"	""	"3"	"4"	"6"	"4"	"1683"	"192.6"	"8.09"	"1124.89"	"9.33"	"3"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00307, Pf00412, Pf00595, Pf15949"	"4008"	"ENSG00000136153"	"LMO7"	"E9PLH4; hsa:4008; O15462; O95346; Q5TBK6; Q8WWI1; Q9UKC1; Q9UQM5; Q9Y6A7"	""	"Antigen processing: Ubiquitination & Proteasome degradation; Neddylation; Signaling by ALK fusions and activated point mutants"	"3"	"0"	"187.3"	"161.0"	"173.4"	"179.6"	"169.4"	"156.4"	"184.4"	"308.4"	"325.3"	"650.5"	"825.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13952"	"Nuclear transcription factor Y subunit gamma OS=Homo sapiens OX=9606 GN=NFYC PE=1 SV=3"	"0.000"	""	"7"	"2"	"4"	"2"	"458"	"50.3"	"6.10"	"949.67"	"9.32"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125"	"4802"	"ENSG00000066136"	"NFYC"	"B4DUS6; B4DW63; D3DPV9; F8VWM3; hsa:4802; Q13952; Q59GY4; Q5T6K8; Q5T6K9; Q5T6L1; Q5TZR6; Q92869; Q9HBX1; Q9NXB5; Q9UM67; Q9UML0; Q9UMT7"	""	"PPARA activates gene expression; Activation of gene expression by SREBF (SREBP); FOXO-mediated transcription of cell death genes; ATF4 activates genes in response to endoplasmic reticulum  stress; ATF6 (ATF6-alpha) activates chaperone genes"	"5"	"0"	"49.7"	"30.9"	"62.8"	"61.5"	"44.8"	"70.6"	"74.5"	"116.8"	"148.1"	"322.4"	"398.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H501"	"ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1"	"0.000"	""	"3"	"2"	"4"	"2"	"851"	"98.7"	"5.11"	"893.50"	"9.31"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf08159"	"51575"	"ENSG00000089048"	"ESF1"	"hsa:51575; Q86X92; Q9H501; Q9H9Q5; Q9HA35; Q9NX93; Q9P1S6"	""	""	"0"	"0"	"159.9"	"141.1"	"175.2"	"143.1"	"147.4"	"158.7"	"184.4"	"217.4"	"210.0"	"361.7"	"496.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15691"	"Microtubule-associated protein RP/EB family member 1 OS=Homo sapiens OX=9606 GN=MAPRE1 PE=1 SV=3"	"0.000"	""	"21"	"3"	"4"	"3"	"268"	"30.0"	"5.14"	"795.55"	"9.27"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf03271"	"22919"	"ENSG00000101367"	"MAPRE1"	"B2R6I7; E1P5M8; hsa:22919; Q15691; Q3KQS8"	"Microtubule cytoskeleton regulation"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; The role of GTSE1 in G2/M progression after G2 checkpoint"	"15"	"0"	"63.5"	"71.9"	"73.8"	"63.9"	"75.9"	"68.5"	"82.5"	"175.3"	"146.6"	"457.1"	"1602.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A6NMY6"	"Putative annexin A2-like protein OS=Homo sapiens OX=9606 GN=ANXA2P2 PE=5 SV=2"	"0.000"	""	"10"	"3"	"6"	"3"	"339"	"38.6"	"6.95"	"1002.52"	"9.27"	"3"	"3"	"transport"	"non-structural extracellular;extracellular matrix;plasma membrane;other membranes;nucleus;other cell component"	"transporter activity;enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00191"	""	""	"ANXA2P2"	"A6NMY6"	""	""	"0"	"0"	"63.3"	"74.8"	"127.8"	"85.8"	"70.3"	"70.8"	"86.4"	"222.7"	"194.5"	"405.5"	"800.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NR56"	"Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2"	"0.000"	""	"10"	"3"	"5"	"3"	"388"	"41.8"	"8.90"	"684.54"	"9.27"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00642, Pf14608"	"4154"	"ENSG00000152601"	"MBNL1"	"E9PBW7; hsa:4154; O43311; O43797; Q86UV8; Q86UV9; Q96P92; Q96RE3; Q9NR56"	"Adipogenesis"	""	"1"	"0"	"237.8"	"224.9"	"233.5"	"232.3"	"236.6"	"200.2"	"271.3"	"400.6"	"394.5"	"745.1"	"961.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y295"	"Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1"	"0.000"	""	"10"	"3"	"6"	"3"	"367"	"40.5"	"8.90"	"1051.45"	"9.26"	"3"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01926, Pf02824, Pf16897"	"4733"	"ENSG00000185721"	"DRG1"	"B2RDS8; hsa:4733; Q6FGP8; Q8WW69; Q9UGF2; Q9Y295"	""	""	"0"	"0"	"212.7"	"211.1"	"258.5"	"229.2"	"255.3"	"248.7"	"313.2"	"434.2"	"421.6"	"952.9"	"937.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13425"	"Beta-2-syntrophin OS=Homo sapiens OX=9606 GN=SNTB2 PE=1 SV=1"	"0.000"	""	"6"	"3"	"7"	"3"	"540"	"57.9"	"8.82"	"1717.44"	"9.25"	"3"	"3"	""	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00595, Pf18012"	"6645"	"ENSG00000168807"	"SNTB2"	"hsa:6645; Q13425; Q9BY09"	""	""	"0"	"0"	"206.5"	"112.9"	"203.7"	"185.8"	"189.1"	"157.7"	"248.5"	"399.8"	"461.3"	"926.7"	"1055.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49207"	"60S ribosomal protein L34 OS=Homo sapiens OX=9606 GN=RPL34 PE=1 SV=3"	"0.000"	""	"21"	"3"	"6"	"3"	"117"	"13.3"	"11.47"	"1017.38"	"9.25"	"3"	"3"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01199"	"6164"	"ENSG00000109475"	"RPL34"	"hsa:6164; P49207; Q6FG66; Q9BUZ2"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"511.6"	"518.2"	"406.9"	"372.8"	"391.4"	"369.0"	"608.7"	"1133.9"	"1005.4"	"2377.5"	"3886.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14696"	"LRP chaperone MESD OS=Homo sapiens OX=9606 GN=MESD PE=1 SV=2"	"0.000"	""	"10"	"2"	"6"	"2"	"234"	"26.1"	"7.78"	"1342.67"	"9.24"	"2"	"2"	"cell-cell signaling;protein metabolism;other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi"	"signal transduction activity or receptor binding;other molecular function"	"Pf10185"	"23184"	"ENSG00000117899"	"MESD"	"B4DW84; D3DW96; hsa:23184; Q14696; Q969U1"	""	""	"0"	"0"	"46.6"	"36.3"	"55.4"	"40.7"	"50.7"	"64.7"	"79.1"	"484.4"	"543.6"	"981.5"	"1382.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09110"	"3-ketoacyl-CoA thiolase, peroxisomal OS=Homo sapiens OX=9606 GN=ACAA1 PE=1 SV=2"	"0.000"	""	"8"	"2"	"4"	"2"	"424"	"44.3"	"8.44"	"934.88"	"9.23"	"2"	"2"	"other metabolic processes"	"non-structural extracellular;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00108, Pf02803"	"30"	"ENSG00000060971"	"ACAA1"	"G5E935; hsa:30; P09110; Q96CA6"	"PPAR-alpha pathway; Nuclear receptors meta-pathway; Amino acid metabolism; PPAR signaling pathway; Eicosanoid metabolism via cyclooxygenases (COX); Eicosanoid metabolism via lipooxygenases (LOX)"	"Neutrophil degranulation; TYSND1 cleaves peroxisomal proteins; alpha-linolenic acid (ALA) metabolism; Beta-oxidation of very long chain fatty acids"	"11"	"0"	"85.9"	"58.6"	"83.1"	"74.6"	"67.2"	"65.1"	"100.1"	"185.5"	"186.9"	"449.7"	"624.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBS4"	"DnaJ homolog subfamily B member 11 OS=Homo sapiens OX=9606 GN=DNAJB11 PE=1 SV=1"	"0.000"	""	"13"	"3"	"5"	"3"	"358"	"40.5"	"6.18"	"1438.03"	"9.23"	"3"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"non-structural extracellular;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00226, Pf01556"	"51726"	"ENSG00000090520"	"DNAJB11"	"hsa:51726; Q542Y5; Q542Y9; Q6IAQ8; Q96JC6; Q9UBS4"	"Photodynamic therapy-induced unfolded protein response"	"XBP1(S) activates chaperone genes"	"2"	"0"	"332.1"	"233.9"	"348.8"	"334.8"	"288.2"	"301.1"	"398.4"	"639.9"	"574.4"	"944.8"	"1144.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4L1"	"Hypoxia up-regulated protein 1 OS=Homo sapiens OX=9606 GN=HYOU1 PE=1 SV=1"	"0.000"	""	"3"	"2"	"3"	"2"	"999"	"111.3"	"5.22"	"286.30"	"9.22"	"1"	"2"	"protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"non-structural extracellular;ER/Golgi;other cell component"	"other molecular function"	"Pf00012"	"10525"	"ENSG00000149428; ENSG00000280682"	"HYOU1"	"A8C1Z0; B7Z909; hsa:10525; Q2I204; Q53H25; Q9Y4L1"	"VEGFA-VEGFR2 signaling"	"XBP1(S) activates chaperone genes; Scavenging by Class F Receptors"	"3"	"0"	"69.0"	"54.0"	"76.4"	"73.4"	"77.6"	"75.9"	"92.4"	"188.9"	"190.8"	"683.2"	"1160.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H2U1"	"ATP-dependent DNA/RNA helicase DHX36 OS=Homo sapiens OX=9606 GN=DHX36 PE=1 SV=2"	"0.000"	""	"4"	"2"	"3"	"2"	"1008"	"114.7"	"7.68"	"557.90"	"9.22"	"1"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"170506"	"ENSG00000174953"	"DHX36"	"B2RB00; hsa:170506; Q70JU3; Q8IYE5; Q9H2U1; Q9P240"	"VEGFA-VEGFR2 signaling"	"DEx/H-box helicases activate type I IFN and inflammatory cytokines production"	"2"	"0"	"34.3"	"22.8"	"36.6"	"41.4"	"36.1"	"32.8"	"42.7"	"61.3"	"75.2"	"135.5"	"181.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52298"	"Nuclear cap-binding protein subunit 2 OS=Homo sapiens OX=9606 GN=NCBP2 PE=1 SV=1"	"0.000"	""	"23"	"3"	"6"	"3"	"156"	"18.0"	"8.21"	"1174.69"	"9.20"	"3"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"22916"	"ENSG00000114503"	"NCBP2"	"B2RE91; B4DMK7; E9PAR5; hsa:22916; P52298; Q14924; Q2TS50"	"mRNA processing; 3q29 copy number variation syndrome"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Abortive elongation of HIV-1 transcript in the absence of Tat; RNA Polymerase II Pre-transcription Events; RNA polymerase II transcribes snRNA genes; mRNA Capping; mRNA Splicing - Major Pathway; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Signaling by FGFR2 IIIa TM; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; snRNP Assembly; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"29"	"0"	"336.5"	"198.1"	"336.4"	"275.2"	"274.2"	"284.0"	"401.1"	"543.7"	"494.6"	"1118.9"	"1497.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14573"	"Inositol 1,4,5-trisphosphate receptor type 3 OS=Homo sapiens OX=9606 GN=ITPR3 PE=1 SV=2"	"0.000"	""	"1"	"4"	"7"	"2"	"2671"	"303.9"	"6.48"	"1210.23"	"9.20"	"4"	"3"	"transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf00520, Pf01365, Pf02815, Pf08454, Pf08709"	"3710"	"ENSG00000096433"	"ITPR3"	"hsa:3710; Q14573; Q14649; Q5TAQ2"	"Alzheimer's disease and miRNA effects; Myometrial relaxation and contraction pathways; MFAP5-mediated ovarian cancer cell motility and invasiveness; GPR40 pathway; Vitamin D-sensitive calcium signaling in depression; Airway smooth muscle cell contraction; Pleural mesothelioma; Alzheimer's disease; GDNF signaling; Calcium regulation in cardiac cells"	"Ion homeostasis; Role of phospholipids in phagocytosis; FCERI mediated Ca+2 mobilization; FCGR3A-mediated IL10 synthesis; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Sensory perception of sweet, bitter, and umami (glutamate) taste; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Ca2+ pathway; VEGFR2 mediated cell proliferation; Elevation of cytosolic Ca2+ levels; PLC beta mediated events; DAG and IP3 signaling; CLEC7A (Dectin-1) induces NFAT activation; Effects of PIP2 hydrolysis"	"25"	"0"	"21.2"	"12.3"	"18.2"	"16.5"	"14.6"	"15.6"	"21.4"	"47.9"	"52.7"	"137.9"	"254.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q06787"	"Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1"	"0.000"	""	"5"	"3"	"6"	"2"	"632"	"71.1"	"7.42"	"911.74"	"9.18"	"3"	"3"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"cytoskeletal activity;translation activity;nucleic acid binding activity;other molecular function"	"Pf00013, Pf05641, Pf12235, Pf16098, Pf17904, Pf18336"	"2332"	"ENSG00000102081"	"FMR1"	"A6NNH4; D3DWT0; D3DWT1; D3DWT2; G8JL90; hsa:2332; Q06787; Q16578; Q5PQZ6; Q99054"	"Ovarian infertility; Serotonin and anxiety; Prader-Willi and Angelman syndrome; Fragile X syndrome; Disruption of postsynaptic signaling by CNV; 15q11.2 copy number variation syndrome; Primary ovarian insufficiency"	""	"7"	"1"	"252.6"	"200.1"	"307.3"	"257.1"	"239.2"	"263.6"	"323.6"	"561.7"	"474.8"	"1067.9"	"1312.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L4I2"	"Arginine/serine-rich coiled-coil protein 2 OS=Homo sapiens OX=9606 GN=RSRC2 PE=1 SV=1"	"0.000"	""	"10"	"6"	"9"	"6"	"434"	"50.5"	"11.33"	"1841.89"	"9.18"	"6"	"3"	""	""	""	"Pf15477"	"65117"	"ENSG00000111011"	"RSRC2"	"hsa:65117; Q6N040; Q6NW16; Q7L4I2; Q9H864"	""	""	"0"	"0"	"1250.8"	"884.5"	"1021.6"	"1019.0"	"878.6"	"967.6"	"1218.8"	"1919.8"	"1726.9"	"3056.4"	"3779.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35244"	"Replication protein A 14 kDa subunit OS=Homo sapiens OX=9606 GN=RPA3 PE=1 SV=1"	"0.000"	""	"32"	"2"	"3"	"2"	"121"	"13.6"	"5.08"	"435.83"	"9.16"	"1"	"2"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf08661"	"6119"	"ENSG00000106399"	"RPA3"	"hsa:6119; P35244; Q549U6"	"Retinoblastoma gene in cancer; G1 to S cell cycle control; DNA replication; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"HSF1 activation; Fanconi Anemia Pathway; Regulation of HSF1-mediated heat shock response; Regulation of TP53 Activity through Phosphorylation; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Meiotic recombination; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Removal of the Flap Intermediate; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"36"	"0"	"92.3"	"80.9"	"102.8"	"113.4"	"90.7"	"96.3"	"118.8"	"197.5"	"208.6"	"411.4"	"595.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y3Z3"	"Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 OS=Homo sapiens OX=9606 GN=SAMHD1 PE=1 SV=2"	""	""	"5"	"3"	"3"	"3"	"626"	"72.2"	"7.14"	""	"9.15"	""	"3"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01966, Pf07647"	"25939"	"ENSG00000101347"	"SAMHD1"	"B4E2A5; E1P5V2; hsa:25939; Q5JXG8; Q8N491; Q9H004; Q9H005; Q9H3U9; Q9Y3Z3"	""	"Interferon alpha/beta signaling; Nucleotide catabolism"	"2"	"0"	"35.3"	"25.5"	"42.2"	"40.3"	"33.8"	"33.1"	"48.0"	"99.9"	"89.2"	"303.1"	"453.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15785"	"Mitochondrial import receptor subunit TOM34 OS=Homo sapiens OX=9606 GN=TOMM34 PE=1 SV=2"	"0.000"	""	"10"	"2"	"4"	"2"	"309"	"34.5"	"8.98"	"812.62"	"9.13"	"2"	"2"	"cell organization and biogenesis;transport"	"other membranes;cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00515"	"10953"	"ENSG00000025772"	"TOMM34"	"hsa:10953; Q15785; Q53GH9; Q6IBN7; Q9NTZ3"	""	""	"0"	"0"	"130.5"	"80.2"	"156.4"	"157.3"	"146.0"	"133.0"	"179.9"	"248.8"	"269.8"	"511.6"	"555.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H8H0"	"Nucleolar protein 11 OS=Homo sapiens OX=9606 GN=NOL11 PE=1 SV=1"	"0.000"	""	"5"	"3"	"4"	"3"	"719"	"81.1"	"6.07"	"388.02"	"9.12"	"1"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	"Pf08168"	"25926"	"ENSG00000130935"	"NOL11"	"B7Z5V9; hsa:25926; Q7L5S1; Q9H8H0; Q9UG18"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"45.8"	"36.7"	"55.7"	"52.6"	"51.9"	"44.2"	"55.7"	"85.0"	"88.9"	"169.8"	"231.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62861"	"40S ribosomal protein S30 OS=Homo sapiens OX=9606 GN=FAU PE=1 SV=1"	"0.000"	""	"20"	"3"	"5"	"3"	"59"	"6.6"	"12.15"	"745.49"	"9.12"	"2"	"3"	"protein metabolism;other metabolic processes;stress response"	"non-structural extracellular;cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf04758"	""	"ENSCHIG00000017446; ENSJHYG00000000624; ENSLLEG00000000574"	"Fau; FAU"	"A0A452F0A8; A0A7L0YXB0; A0A8C5IE60; A0A8C5LQJ8; P0C2F0; P62860; P62863; P62864; P62866; P62867; Q05472; Q5RC12; Q8HYI8; Q920W7; Q95261"	""	""	"0"	"0"	"229.0"	"191.1"	"235.9"	"197.0"	"208.6"	"233.0"	"295.5"	"344.6"	"354.3"	"549.1"	"674.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13084"	"39S ribosomal protein L28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL28 PE=1 SV=4"	"0.000"	""	"16"	"3"	"4"	"3"	"256"	"30.1"	"8.29"	"780.48"	"9.11"	"2"	"2"	"protein metabolism;other metabolic processes"	"other membranes;cytosol;mitochondrion;translational apparatus"	"other molecular function"	"Pf00830"	"10573"	"ENSG00000086504"	"MRPL28"	"B2RCM4; D3DU46; hsa:10573; Q13084; Q4TT39; Q96S26; Q9BQD8; Q9BR04"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"290.5"	"250.1"	"250.7"	"242.8"	"236.7"	"248.5"	"332.3"	"466.1"	"444.5"	"969.8"	"1755.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IUH3"	"RNA-binding protein 45 OS=Homo sapiens OX=9606 GN=RBM45 PE=1 SV=1"	"0.000"	""	"6"	"3"	"6"	"3"	"476"	"53.5"	"7.17"	"1161.29"	"9.10"	"3"	"3"	"developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"129831"	"ENSG00000155636"	"RBM45"	"hsa:129831; Q6NYL0; Q8IUH3; Q8NFC9"	""	""	"0"	"0"	"487.9"	"415.5"	"481.6"	"445.6"	"384.9"	"447.8"	"553.7"	"612.5"	"592.7"	"1023.9"	"1430.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKS6"	"Protein kinase C and casein kinase substrate in neurons protein 3 OS=Homo sapiens OX=9606 GN=PACSIN3 PE=1 SV=2"	"0.000"	""	"5"	"3"	"6"	"3"	"424"	"48.5"	"6.18"	"1183.79"	"9.08"	"3"	"3"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00611, Pf14604"	"29763"	"ENSG00000165912"	"PACSIN3"	"A6NH84; hsa:29763; Q9H331; Q9NWV9; Q9UKS6"	""	"Clathrin-mediated endocytosis"	"1"	"0"	"107.1"	"108.5"	"127.0"	"106.9"	"122.6"	"114.1"	"152.4"	"363.3"	"350.3"	"1072.5"	"1592.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2S6"	"Translation machinery-associated protein 7 OS=Homo sapiens OX=9606 GN=TMA7 PE=1 SV=1"	"0.000"	""	"36"	"4"	"9"	"3"	"64"	"7.1"	"9.99"	"1929.93"	"9.08"	"4"	"2"	""	""	""	"Pf09072"	"51372"	"ENSG00000232112"	"TMA7"	"hsa:51372; Q9P052; Q9Y2S6"	""	""	"0"	"1"	"1554.6"	"1335.0"	"1518.5"	"1444.4"	"1327.5"	"1308.9"	"1754.3"	"2137.7"	"1969.9"	"1772.0"	"1800.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9GZN8"	"UPF0687 protein C20orf27 OS=Homo sapiens OX=9606 GN=C20orf27 PE=1 SV=3"	"0.000"	""	"20"	"2"	"3"	"2"	"174"	"19.3"	"6.84"	"398.51"	"9.07"	"1"	"2"	"other metabolic processes;other biological processes"	"non-structural extracellular"	"other molecular function"	"Pf15006"	"54976"	"ENSG00000101220"	"ADISSP"	"A8K4J0; D3DVX8; hsa:54976; Q5JX81; Q9GZN8; Q9NWX3"	""	""	"0"	"0"	"34.3"	"20.1"	"38.1"	"32.0"	"29.9"	"31.6"	"44.2"	"214.2"	"207.0"	"600.4"	"831.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43314"	"Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 OS=Homo sapiens OX=9606 GN=PPIP5K2 PE=1 SV=3"	"0.000"	""	"4"	"4"	"6"	"3"	"1243"	"140.3"	"8.22"	"966.52"	"9.04"	"3"	"3"	"other metabolic processes;other biological processes"	"cytosol"	"kinase activity;other molecular function"	"Pf00328, Pf18086"	"23262"	"ENSG00000145725"	"PPIP5K2"	"A1NI53; A6NGS8; hsa:23262; O43314; Q8TB50"	""	"Synthesis of pyrophosphates in the cytosol"	"1"	"0"	"59.4"	"43.0"	"74.9"	"65.0"	"64.6"	"61.7"	"81.6"	"175.7"	"178.9"	"370.0"	"405.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75367"	"Core histone macro-H2A.1 OS=Homo sapiens OX=9606 GN=MACROH2A1 PE=1 SV=4"	"0.000"	""	"5"	"3"	"6"	"3"	"372"	"39.6"	"9.79"	"970.86"	"9.04"	"3"	"3"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00125, Pf01661, Pf16211"	"100394084; 100998964; 101131222; 101381952; 101564704; 101706296; 102008188; 102123677; 103079324; 104855290; 105467125; 105506940; 105531308; 105816031; 105869993; 108529540; 462076; 481514; 711836"	"ENSAMEG00000017887; ENSBMSG00010001156; ENSCAFG00000001076; ENSCAFG00020007175; ENSCAFG00030007355; ENSCAFG00040009734; ENSCANG00000022762; ENSCJAG00000005818; ENSCLAG00000016530; ENSCWAG00000001657; ENSFCAG00000013924; ENSGGOG00000001707; ENSLCNG00005003680; ENSMICG00000005677; ENSMLEG00000037795; ENSMMNG00015002866; ENSMNEG00000031666; ENSMPUG00000010011; ENSPANG00000002758; ENSPCOG00000013464; ENSPCTG00005011747; ENSPLOG00000000479; ENSPPAG00000029258; ENSPPYG00000015799; ENSPSMG00000021213; ENSPSNG00000019193; ENSPTRG00000017256; ENSRBIG00000034425; ENSRROG00000045755; ENSSBOG00000034640; ENSSSUG00005001976; ENSSVLG00005008251; ENSTGEG00000021330; ENSVVUG00000017487"	"H2afy; H2AFY; LOC100466888; LOC101338325; LOC101381952; LOC101564704; LOC102987354; LOC103079324; LOC103663804; LOC105869993; LOC106989149; LOC110591142; LOC111141291; LOC111182462; LOC112404331; LOC112625777; LOC112815157; LOC112861289; LOC112917035; LOC113928700; LOC114891795; LOC115516119; LOC116529369; LOC116750637; MACROH2A1"	"A0A091CNU6; A0A096N0E8; A0A2J8LRK8; A0A2J8VQ67; A0A2K5HRC8; A0A2K5W7N1; A0A2K5ZHE4; A0A2K6BUT6; A0A2K6EU20; A0A2K6LBL0; A0A2K6RXM8; A0A2K6UYW1; A0A2R9A926; A0A2U3WAW1; A0A2Y9IU30; A0A2Y9PFA0; A0A2Y9SS16; A0A340XJ26; A0A341BZA5; A0A3Q7NDG6; A0A3Q7S763; A0A484GVZ9; A0A485NYK5; A0A5S6R987; A0A667GC30; A0A673T0D7; A0A6G1ASZ6; A0A6J2AVA7; A0A6J2DX40; A0A6J3FC37; A0A6J3R528; A0A6P3F5E4; A0A6P6HX24; A0A8B7G616; A0A8C0C880; A0A8C0K484; A0A8C0S4U0; A0A8C2W4Z6; A0A8C3VQP8; A0A8C6F240; A0A8C8WAC0; A0A8C9AAB1; A0A8C9CK62; A0A8D2BC14; A0A8D2FWT2; A0A8I5UBU0; A0A8J8XTA7; A0A8M1F844; A0A8M1MQV0; A0A8P0N4A7; aju:106989149; cang:105506940; D2GVK3; dle:111182462; elk:111141291; F7HN69; G3QH59; G5BQ26; G7MUD7; ggo:101131222; H2QRI8; I2CUE9; lve:103079324; M3WJR3; M3YF29; mcf:102123677; mleu:105531308; mmur:105869993; mni:105467125; mpuf:101692673; nsu:110591142; oro:101381952; panu:100998964; pcad:102987354; pcoq:105816031; ptr:462076; rbb:108529540; sbq:101050376; umr:103663804; vvp:112917035; zca:113928700"	""	""	"0"	"0"	"232.7"	"184.4"	"286.2"	"222.7"	"215.4"	"226.0"	"313.1"	"517.9"	"513.7"	"1066.8"	"1501.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43181"	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS4 PE=1 SV=1"	"0.000"	""	"21"	"3"	"4"	"3"	"175"	"20.1"	"10.30"	"393.13"	"9.04"	"1"	"3"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;mitochondrion"	"transporter activity"	"Pf04800"	"4724"	"ENSG00000164258"	"NDUFS4"	"hsa:4724; O43181; Q9BS69"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"107.9"	"86.9"	"117.2"	"116.7"	"122.3"	"114.6"	"133.2"	"314.3"	"293.0"	"602.2"	"697.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q02952"	"A-kinase anchor protein 12 OS=Homo sapiens OX=9606 GN=AKAP12 PE=1 SV=4"	""	""	"2"	"3"	"3"	"3"	"1782"	"191.4"	"4.41"	""	"9.02"	""	"3"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf03832, Pf10522"	"9590"	"ENSG00000131016"	"AKAP12"	"hsa:9590; O00310; O00498; Q02952; Q4LE68; Q5SZ80; Q5TGN1; Q68D82; Q99970"	"G protein signaling pathways"	"RHOD GTPase cycle; RHOF GTPase cycle"	"3"	"0"	"188.0"	"158.5"	"201.1"	"185.5"	"161.4"	"168.2"	"216.5"	"285.5"	"251.4"	"539.9"	"953.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P57076"	"Cilia- and flagella-associated protein 298 OS=Homo sapiens OX=9606 GN=CFAP298 PE=1 SV=1"	"0.000"	""	"11"	"2"	"3"	"2"	"290"	"33.2"	"7.44"	"289.42"	"9.02"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	""	"Pf11069"	"56683"	"ENSG00000159079"	"CFAP298"	"hsa:56683; P57076; Q53FH0"	"Ciliopathies"	""	"1"	"0"	"71.6"	"80.3"	"82.6"	"71.8"	"85.5"	"91.3"	"104.2"	"196.3"	"209.4"	"453.0"	"534.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96C36"	"Pyrroline-5-carboxylate reductase 2 OS=Homo sapiens OX=9606 GN=PYCR2 PE=1 SV=1"	"0.000"	""	"9"	"2"	"4"	"2"	"320"	"33.6"	"7.77"	"780.56"	"8.97"	"2"	"2"	"other metabolic processes;stress response"	"mitochondrion"	"other molecular function"	"Pf03807, Pf14748"	"29920"	"ENSG00000143811"	"PYCR2"	"A8K798; hsa:29920; Q7Z515; Q96C36; Q9Y5J4"	"Metabolic reprogramming in colon cancer"	"Glutamate and glutamine metabolism"	"2"	"0"	"63.9"	"50.5"	"64.9"	"67.4"	"73.5"	"61.1"	"82.0"	"129.4"	"132.0"	"261.0"	"362.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46100"	"Transcriptional regulator ATRX OS=Homo sapiens OX=9606 GN=ATRX PE=1 SV=5"	"0.000"	""	"1"	"2"	"3"	"2"	"2492"	"282.4"	"6.58"	"302.90"	"8.97"	"1"	"2"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"100.3"	"68.8"	"117.3"	"89.1"	"98.4"	"97.4"	"126.0"	"195.0"	"207.1"	"529.2"	"797.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43823"	"A-kinase anchor protein 8 OS=Homo sapiens OX=9606 GN=AKAP8 PE=1 SV=1"	"0.000"	""	"7"	"2"	"3"	"2"	"692"	"76.1"	"5.15"	"630.18"	"8.96"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"mitochondrion;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04988"	"10270"	"ENSG00000105127"	"AKAP8"	"hsa:10270; O43823"	"G protein signaling pathways"	""	"1"	"0"	"58.9"	"59.9"	"76.8"	"64.2"	"69.4"	"57.0"	"79.7"	"103.7"	"87.9"	"147.4"	"191.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96HP4"	"Oxidoreductase NAD-binding domain-containing protein 1 OS=Homo sapiens OX=9606 GN=OXNAD1 PE=1 SV=1"	"0.000"	""	"10"	"2"	"4"	"2"	"312"	"34.8"	"8.37"	"797.34"	"8.94"	"2"	"2"	""	""	"other molecular function"	"Pf00175"	"92106"	"ENSG00000154814"	"OXNAD1"	"hsa:92106; Q2HYC7; Q59FA4; Q96HP4"	""	""	"0"	"0"	"29.4"	"21.8"	"28.3"	"34.4"	"29.4"	"34.4"	"53.4"	"155.1"	"148.8"	"410.4"	"544.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NFJ9"	"Bardet-Biedl syndrome 1 protein OS=Homo sapiens OX=9606 GN=BBS1 PE=1 SV=1"	"0.000"	""	"5"	"2"	"4"	"2"	"593"	"65.0"	"7.93"	"1010.98"	"8.93"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf14779"	"582"	"ENSG00000174483"	"BBS1"	"hsa:582; Q32MM9; Q32MN0; Q8NFJ9; Q96SN4"	"Ciliary landscape; Genes related to primary cilium development (based on CRISPR); Joubert syndrome; Ciliopathies; Bardet-Biedl syndrome"	"BBSome-mediated cargo-targeting to cilium"	"6"	"0"	"21.6"	"16.2"	"26.9"	"24.6"	"12.7"	"21.4"	"36.9"	"137.7"	"158.0"	"363.5"	"403.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WVY7"	"Ubiquitin-like domain-containing CTD phosphatase 1 OS=Homo sapiens OX=9606 GN=UBLCP1 PE=1 SV=2"	"0.000"	""	"10"	"3"	"6"	"3"	"318"	"36.8"	"6.46"	"1170.22"	"8.92"	"3"	"3"	"protein metabolism;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00240, Pf03031"	"134510"	"ENSG00000164332"	"UBLCP1"	"D3DQJ7; hsa:134510; Q8WVY7; Q96DK5"	""	""	"0"	"0"	"100.6"	"64.0"	"101.8"	"86.3"	"85.7"	"87.9"	"108.1"	"997.0"	"1109.5"	"2800.1"	"2826.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NSY1"	"BMP-2-inducible protein kinase OS=Homo sapiens OX=9606 GN=BMP2K PE=1 SV=2"	"0.000"	""	"3"	"2"	"3"	"2"	"1161"	"129.1"	"6.51"	"398.11"	"8.92"	"1"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069, Pf15282"	"55589"	"ENSG00000138756"	"BMP2K"	"hsa:55589; O94791; Q4W5H2; Q8IYF2; Q8N2G7; Q8NHG9; Q9NSY1; Q9NTG8"	""	""	"0"	"0"	"87.6"	"65.0"	"71.3"	"79.8"	"69.0"	"74.4"	"88.6"	"152.2"	"151.5"	"225.3"	"264.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O76021"	"Ribosomal L1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RSL1D1 PE=1 SV=3"	"0.000"	""	"8"	"3"	"5"	"3"	"490"	"54.9"	"10.13"	"1120.00"	"8.92"	"3"	"2"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00687"	"26156"	"ENSG00000171490"	"RSL1D1"	"B4DJ58; D3DUG7; hsa:26156; O76021; Q2M1T7; Q6PL22; Q8IWS7; Q8WUZ1; Q9HDA9; Q9Y3Z9"	""	""	"0"	"0"	"253.8"	"212.6"	"260.0"	"219.9"	"247.2"	"249.7"	"294.6"	"329.3"	"309.0"	"546.4"	"772.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13206"	"Probable ATP-dependent RNA helicase DDX10 OS=Homo sapiens OX=9606 GN=DDX10 PE=1 SV=2"	"0.000"	""	"2"	"1"	"4"	"1"	"875"	"100.8"	"8.63"	"1295.85"	"8.87"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00270, Pf00271, Pf13959"	"1662"	"ENSG00000178105"	"DDX10"	"B2RCQ3; hsa:1662; Q13206; Q5BJD8"	""	""	"0"	"0"	"60.7"	"49.2"	"63.1"	"51.5"	"55.7"	"55.6"	"73.7"	"135.8"	"146.9"	"346.8"	"512.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95208"	"Epsin-2 OS=Homo sapiens OX=9606 GN=EPN2 PE=1 SV=3"	"0.000"	""	"4"	"3"	"6"	"3"	"641"	"68.4"	"7.52"	"966.88"	"8.87"	"3"	"3"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01417"	"22905"	"ENSG00000072134"	"EPN2"	"A8MTV8; B3KRX8; E9PBC2; hsa:22905; O95207; O95208; Q52LD0; Q9H7Z2; Q9UPT7"	""	"Cargo recognition for clathrin-mediated endocytosis"	"2"	"0"	"95.2"	"102.5"	"201.0"	"228.0"	"253.6"	"332.6"	"394.4"	"543.5"	"513.8"	"845.0"	"946.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75323"	"Protein NipSnap homolog 2 OS=Homo sapiens OX=9606 GN=NIPSNAP2 PE=1 SV=1"	"0.000"	""	"11"	"3"	"5"	"2"	"286"	"33.7"	"9.36"	"1001.76"	"8.86"	"3"	"2"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"other membranes;mitochondrion"	""	"Pf07978"	"2631"	"ENSG00000146729"	"NIPSNAP2"	"C9IYJ3; hsa:2631; O43801; O75323; Q53X96"	""	"RHOJ GTPase cycle; RHOH GTPase cycle"	"2"	"0"	"197.8"	"169.0"	"165.0"	"165.6"	"167.3"	"174.1"	"211.5"	"345.5"	"312.1"	"693.3"	"850.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IWI9"	"MAX gene-associated protein OS=Homo sapiens OX=9606 GN=MGA PE=1 SV=4"	"0.000"	""	"1"	"3"	"5"	"3"	"3065"	"336.0"	"6.90"	"575.43"	"8.86"	"2"	"3"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00010, Pf00907, Pf16059"	"23269"	"ENSG00000174197"	"MGA"	"B9EGR5; E7ENI0; F5H7K2; hsa:23269; Q8IWI9; Q9H8R3; Q9H9N7; Q9UG69; Q9Y4E9"	"Pathways affected in adenoid cystic carcinoma"	"Transcriptional Regulation by E2F6"	"2"	"0"	"207.4"	"173.3"	"177.4"	"170.2"	"159.0"	"159.0"	"201.9"	"292.8"	"307.3"	"521.0"	"643.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q5T5C0"	"Syntaxin-binding protein 5 OS=Homo sapiens OX=9606 GN=STXBP5 PE=1 SV=1"	""	""	"3"	"2"	"2"	"2"	"1151"	"127.5"	"7.28"	""	"8.84"	""	"2"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00400, Pf08366, Pf08596"	"134957"	"ENSG00000164506"	"STXBP5"	"hsa:134957; Q14DF3; Q5T5C0; Q5T5C1; Q5T5C2; Q8NBG8; Q96NG9"	""	""	"0"	"0"	"10.0"	"8.0"	"5.9"	"13.1"	"5.5"	"6.8"	"16.4"	"64.7"	"75.7"	"249.9"	"413.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75179"	"Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3"	"0.000"	""	"1"	"3"	"6"	"3"	"2603"	"274.1"	"6.52"	"1031.82"	"8.83"	"3"	"3"	"stress response;developmental processes;other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf00013, Pf12796"	"26057"	"ENSG00000132466"	"ANKRD17"	"E7EUV3; G5E964; hsa:26057; O75179; Q6PJ85; Q6PK85; Q6PKA2; Q86XI3; Q8NDR5; Q96I86; Q9H288; Q9H6J9"	""	""	"0"	"0"	"72.9"	"65.3"	"75.7"	"68.6"	"66.1"	"69.4"	"97.6"	"144.2"	"133.1"	"249.0"	"272.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62873"	"Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 OS=Homo sapiens OX=9606 GN=GNB1 PE=1 SV=3"	"0.000"	""	"9"	"2"	"4"	"2"	"340"	"37.4"	"6.00"	"703.26"	"8.82"	"2"	"2"	"cell-cell signaling;cell cycle OR cell proliferation;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00400"	"2782"	"ENSG00000078369"	"GNB1"	"B1AJZ7; hsa:2782; P04697; P04901; P62873; Q1RMY8"	"Nicotine effect on dopaminergic neurons; Thyroid stimulating hormone (TSH) signaling pathway; Corticotropin-releasing hormone signaling pathway; Myometrial relaxation and contraction pathways; G protein signaling pathways; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Ras signaling; 1p36 copy number variation syndrome; Calcium regulation in cardiac cells; Estrogen signaling pathway"	"G alpha (q) signalling events; G alpha (12/13) signalling events; Olfactory Signaling Pathway; G alpha (i) signalling events; G alpha (z) signalling events; Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1); ADP signalling through P2Y purinoceptor 12; Extra-nuclear estrogen signaling; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production; Sensory perception of sweet, bitter, and umami (glutamate) taste; Thrombin signalling through proteinase activated receptors (PARs); Activation of G protein gated Potassium channels; G-protein activation; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; G beta:gamma signalling through PI3Kgamma; Prostacyclin signalling through prostacyclin receptor; Adrenaline,noradrenaline inhibits insulin secretion; Ca2+ pathway; G beta:gamma signalling through PLC beta; ADP signalling through P2Y purinoceptor 1; Glucagon-type ligand receptors; Thromboxane signalling through TP receptor; Vasopressin regulates renal water homeostasis via Aquaporins; Presynaptic function of Kainate receptors; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; G beta:gamma signalling through BTK; G beta:gamma signalling through CDC42; Inhibition  of voltage gated Ca2+ channels via Gbeta/gamma subunits; Inactivation, recovery and regulation of the phototransduction cascade; Glucagon signaling in metabolic regulation; Activation of the phototransduction cascade"	"45"	"0"	"82.3"	"83.0"	"79.1"	"82.1"	"81.5"	"76.9"	"101.6"	"280.0"	"283.0"	"1043.2"	"1607.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P60174"	"Triosephosphate isomerase OS=Homo sapiens OX=9606 GN=TPI1 PE=1 SV=3"	"0.000"	""	"9"	"2"	"4"	"2"	"286"	"30.8"	"5.92"	"1004.57"	"8.81"	"2"	"2"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf00121"	""	"ENSPPYG00000004207; ENSPTRG00000004595"	"TPI1"	"A0A2J8JEI5; A0A2J8JEJ3; A0A2J8TBG7; A0A6D2X563; H2NGA4"	""	""	"0"	"0"	"175.1"	"113.6"	"285.6"	"208.5"	"170.7"	"127.5"	"186.5"	"250.1"	"200.4"	"223.4"	"342.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P53597"	"Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLG1 PE=1 SV=4"	"0.000"	""	"9"	"2"	"4"	"2"	"346"	"36.2"	"8.79"	"818.14"	"8.80"	"2"	"2"	"other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf00549, Pf02629"	"8802"	"ENSG00000163541"	"SUCLG1"	"hsa:8802; P53597; Q9BWB0; Q9UNP6"	"Amino acid metabolism; TCA cycle (aka Krebs or citric acid cycle)"	"Citric acid cycle (TCA cycle)"	"3"	"0"	"56.1"	"34.5"	"52.9"	"46.2"	"54.7"	"49.2"	"65.3"	"105.5"	"105.6"	"300.1"	"578.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96A65"	"Exocyst complex component 4 OS=Homo sapiens OX=9606 GN=EXOC4 PE=1 SV=1"	"0.000"	""	"3"	"3"	"6"	"3"	"974"	"110.4"	"6.49"	"1001.48"	"8.77"	"3"	"3"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf04048"	"60412"	"ENSG00000131558"	"EXOC4"	"E9PED2; hsa:60412; Q541U8; Q96A65; Q9C0G4; Q9H9K0; Q9P102"	"Ciliary landscape"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"4"	"0"	"342.2"	"141.4"	"620.4"	"440.2"	"438.2"	"393.6"	"472.6"	"954.0"	"1121.1"	"1517.2"	"1430.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14789"	"Golgin subfamily B member 1 OS=Homo sapiens OX=9606 GN=GOLGB1 PE=1 SV=2"	"0.000"	""	"1"	"3"	"6"	"2"	"3259"	"375.8"	"5.00"	"881.29"	"8.76"	"3"	"3"	"cell organization and biogenesis;other biological processes"	"other membranes;cytosol;ER/Golgi"	"nucleic acid binding activity"	""	"2804"	"ENSG00000173230"	"GOLGB1"	"B2ZZ91; D3DN92; E7EP74; F1T0J2; hsa:2804; Q14398; Q14789"	""	"Golgi Associated Vesicle Biogenesis; COPI-mediated anterograde transport; Signaling by FLT3 fusion proteins"	"3"	"0"	"18.6"	"11.2"	"15.0"	"9.4"	"14.9"	"13.9"	"20.2"	"59.0"	"62.4"	"163.0"	"268.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25440"	"Bromodomain-containing protein 2 OS=Homo sapiens OX=9606 GN=BRD2 PE=1 SV=2"	"0.000"	""	"4"	"2"	"4"	"1"	"801"	"88.0"	"9.09"	"854.48"	"8.75"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00439, Pf17035"	"6046"	"ENSG00000204256; ENSG00000215077; ENSG00000234507; ENSG00000234704; ENSG00000235307"	"BRD2"	"A2AAU0; B0S7P0; B1AZT1; hsa:6046; O00699; O00700; P25440; Q15310; Q5STC9; Q63HQ9; Q658Y7; Q6P3U2; Q969U4"	""	"RUNX3 regulates p14-ARF"	"1"	"0"	"6.1"	"7.4"	"7.8"	"9.2"	"8.6"	"11.8"	"15.2"	"38.7"	"38.3"	"89.7"	"104.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96QZ7"	"Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 OS=Homo sapiens OX=9606 GN=MAGI1 PE=1 SV=3"	"0.000"	""	"3"	"3"	"5"	"2"	"1491"	"164.5"	"7.58"	"1159.77"	"8.74"	"3"	"2"	"cell adhesion;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00397, Pf00595, Pf00625, Pf16663, Pf16666"	"9223"	"ENSG00000151276; ENSG00000282956"	"MAGI1"	"A8K188; hsa:9223; O00309; O43863; O75085; Q96QZ7; Q96QZ8; Q96QZ9"	"Pathways affected in adenoid cystic carcinoma"	""	"1"	"1"	"121.9"	"92.6"	"131.3"	"119.8"	"119.5"	"120.4"	"157.0"	"281.3"	"284.3"	"647.9"	"804.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HAU5"	"Regulator of nonsense transcripts 2 OS=Homo sapiens OX=9606 GN=UPF2 PE=1 SV=1"	"0.000"	""	"2"	"2"	"4"	"2"	"1272"	"147.7"	"5.69"	"972.45"	"8.73"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02854, Pf04050"	"26019"	"ENSG00000151461"	"UPF2"	"A6NLJ5; D3DRS0; hsa:26019; Q14BM1; Q5W0J4; Q8N8U1; Q9H1J2; Q9HAU5; Q9NWL1; Q9P2D9; Q9Y4M9"	""	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	"2"	"0"	"202.4"	"184.1"	"208.5"	"211.3"	"188.3"	"198.2"	"229.1"	"330.6"	"298.2"	"514.7"	"681.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15091"	"Mitochondrial ribonuclease P catalytic subunit OS=Homo sapiens OX=9606 GN=PRORP PE=1 SV=2"	"0.000"	""	"5"	"2"	"4"	"2"	"583"	"67.3"	"8.78"	"822.76"	"8.72"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;nucleus"	"other molecular function"	"Pf16953"	"9692"	"ENSG00000100890"	"PRORP"	"B4DXD9; B4E0S8; B4E211; C4AM93; D3DS99; D3DSA1; hsa:9692; O15091; Q86SZ4; Q86YB5; Q8N5L5"	""	"tRNA processing in the mitochondrion; tRNA modification in the mitochondrion; rRNA processing in the mitochondrion"	"3"	"0"	"46.5"	"46.7"	"51.4"	"49.2"	"49.9"	"55.2"	"71.5"	"97.4"	"90.5"	"179.3"	"224.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60678"	"Protein arginine N-methyltransferase 3 OS=Homo sapiens OX=9606 GN=PRMT3 PE=1 SV=4"	"0.000"	""	"8"	"3"	"6"	"3"	"531"	"59.9"	"5.35"	"980.65"	"8.71"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity;other molecular function"	"Pf06325"	"10196"	"ENSG00000185238"	"PRMT3"	"A0A0A0MSN7; B4DUC7; hsa:10196; O60678"	"Nitric oxide metabolism in cystic fibrosis"	"RMTs methylate histone arginines; Protein methylation"	"3"	"0"	"77.4"	"60.2"	"89.5"	"81.9"	"76.7"	"77.8"	"109.4"	"179.7"	"172.0"	"366.4"	"501.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BRG1"	"Vacuolar protein-sorting-associated protein 25 OS=Homo sapiens OX=9606 GN=VPS25 PE=1 SV=1"	"0.000"	""	"22"	"4"	"8"	"4"	"176"	"20.7"	"6.34"	"2110.73"	"8.70"	"4"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf05871"	"84313"	"ENSG00000131475"	"VPS25"	"B2R581; hsa:84313; Q9BRG1"	""	"HCMV Late Events; Endosomal Sorting Complex Required For Transport (ESCRT)"	"2"	"0"	"134.8"	"104.7"	"167.2"	"163.6"	"169.6"	"209.0"	"275.7"	"567.7"	"560.0"	"1243.6"	"1569.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q3B726"	"DNA-directed RNA polymerase I subunit RPA43 OS=Homo sapiens OX=9606 GN=TWISTNB PE=1 SV=1"	"0.000"	""	"14"	"2"	"3"	"2"	"338"	"37.4"	"6.98"	"633.81"	"8.69"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	"Pf17875"	"221830"	"ENSG00000105849"	"POLR1F"	"A0PJ45; B7Z724; hsa:221830; Q3B726"	"Pyrimidine metabolism; 2q13 copy number variation syndrome"	"NoRC negatively regulates rRNA expression; B-WICH complex positively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"7"	"0"	"5.5"	"15.0"	"6.5"	"4.8"	"9.7"	"7.4"	"14.6"	"24.2"	"32.2"	"62.7"	"86.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P36957"	"Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLST PE=1 SV=4"	"0.000"	""	"6"	"3"	"5"	"3"	"453"	"48.7"	"8.95"	"1219.05"	"8.68"	"3"	"2"	"protein metabolism;other metabolic processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00198, Pf00364"	"1743"	"ENSG00000119689"	"DLST"	"B7Z5W8; E7ESY5; hsa:1743; P36957; Q7LDY7; Q9BQ32"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Metabolic reprogramming in colon cancer; 7q11.23 copy number variation syndrome; 1p36 copy number variation syndrome; 10q11.21q11.23 copy number variation syndrome; TCA cycle (aka Krebs or citric acid cycle)"	"Citric acid cycle (TCA cycle); Lysine catabolism; Glyoxylate metabolism and glycine degradation"	"10"	"0"	"583.8"	"452.5"	"485.2"	"494.4"	"471.3"	"472.6"	"569.0"	"741.9"	"758.5"	"1115.2"	"1500.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96ST3"	"Paired amphipathic helix protein Sin3a OS=Homo sapiens OX=9606 GN=SIN3A PE=1 SV=2"	"0.000"	""	"2"	"3"	"6"	"3"	"1273"	"145.1"	"7.25"	"1045.77"	"8.68"	"3"	"3"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02671, Pf08295, Pf16879"	"25942"	"ENSG00000169375"	"SIN3A"	"B2RNS5; hsa:25942; Q8N8N4; Q8NC83; Q8WV18; Q96L98; Q96ST3; Q9UFQ1"	"Androgen receptor signaling pathway; Retinoblastoma gene in cancer; MECP2 and associated Rett syndrome; Transcription co-factors SKI and SKIL protein partners; Hedgehog signaling pathway; 15q11q13 copy number variation"	"Factors involved in megakaryocyte development and platelet production; NoRC negatively regulates rRNA expression; MECP2 regulates neuronal receptors and channels; FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes; SUMOylation of transcription cofactors; Cytoprotection by HMOX1; MECP2 regulates transcription of neuronal ligands; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Regulation of lipid metabolism by PPARalpha; Regulation of MECP2 expression and activity; STAT3 nuclear events downstream of ALK signaling; Loss of MECP2 binding ability to 5mC-DNA"	"18"	"0"	"157.7"	"136.5"	"152.4"	"134.8"	"130.5"	"146.5"	"181.4"	"316.2"	"295.7"	"873.3"	"1530.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46781"	"40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3"	"0.000"	""	"15"	"4"	"7"	"4"	"194"	"22.6"	"10.65"	"1561.56"	"8.68"	"4"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00163, Pf01479"	"6203"	"ENSG00000170889; ENSG00000274005; ENSG00000274626; ENSG00000274646; ENSG00000274950; ENSG00000275323; ENSG00000277079; ENSG00000277359; ENSG00000278081; ENSG00000278270"	"RPS9"	"A9C4C1; hsa:6203; P46781; Q4QRK7; Q9BVZ0"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Peptide chain elongation; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"20"	"0"	"323.8"	"303.8"	"335.8"	"295.6"	"289.0"	"342.1"	"428.5"	"623.2"	"618.3"	"1349.4"	"1958.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00178"	"GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=GTPBP1 PE=1 SV=3"	"0.000"	""	"7"	"3"	"4"	"3"	"669"	"72.4"	"8.34"	"265.04"	"8.64"	"1"	"3"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;other cytoplasmic organelle"	"nucleic acid binding activity;other molecular function"	"Pf00009"	"9567"	"ENSG00000100226"	"GTPBP1"	"hsa:9567; O00178; Q6IC67"	""	""	"0"	"0"	"64.6"	"55.9"	"78.2"	"68.2"	"64.9"	"64.1"	"95.7"	"134.9"	"160.2"	"358.8"	"568.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16656"	"Nuclear respiratory factor 1 OS=Homo sapiens OX=9606 GN=NRF1 PE=1 SV=1"	"0.000"	""	"4"	"1"	"4"	"1"	"503"	"53.5"	"5.05"	"1026.54"	"8.63"	"1"	"1"	"other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf10491"	"4899"	"ENSG00000106459"	"NRF1"	"A8K4C6; B4DDV6; hsa:4899; Q15305; Q16656; Q96AN2"	"Energy metabolism; Interactions between LOXL4 and oxidative stress pathway; Mitochondrial gene expression; Sildenafil treatment"	"PPARA activates gene expression; Transcriptional activation of mitochondrial biogenesis"	"6"	"0"	"54.2"	"45.0"	"54.7"	"55.2"	"43.5"	"49.0"	"58.3"	"99.2"	"116.6"	"255.0"	"519.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UI30"	"Multifunctional methyltransferase subunit TRM112-like protein OS=Homo sapiens OX=9606 GN=TRMT112 PE=1 SV=1"	"0.000"	""	"22"	"2"	"4"	"2"	"125"	"14.2"	"5.26"	"329.07"	"8.62"	"1"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf03966"	"51504"	"ENSG00000173113"	"TRMT112"	"B2R539; hsa:51504; J3KNG5; Q3MHC7; Q8N2Z4; Q9UI30"	""	"Eukaryotic Translation Termination; Methylation; rRNA modification in the nucleus and cytosol; tRNA modification in the nucleus and cytosol"	"4"	"0"	"91.4"	"69.4"	"98.1"	"95.3"	"98.6"	"92.4"	"102.3"	"168.1"	"168.5"	"338.7"	"468.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60343"	"TBC1 domain family member 4 OS=Homo sapiens OX=9606 GN=TBC1D4 PE=1 SV=2"	"0.000"	""	"3"	"4"	"7"	"4"	"1298"	"146.5"	"7.01"	"1181.08"	"8.61"	"4"	"3"	"transport;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity"	"Pf00566, Pf00640, Pf11830"	"9882"	"ENSG00000136111"	"TBC1D4"	"A7E2X8; B4DU25; B4E235; B6ETN8; B6ETN9; hsa:9882; O60343; Q5W0B9; Q68D14"	"Ciliary landscape; Thyroid hormones production and peripheral downstream signaling effects; Insulin signaling"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"	"4"	"0"	"173.0"	"143.8"	"151.9"	"156.5"	"144.8"	"141.6"	"190.2"	"312.0"	"318.0"	"979.6"	"1463.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O96019"	"Actin-like protein 6A OS=Homo sapiens OX=9606 GN=ACTL6A PE=1 SV=1"	"0.000"	""	"7"	"2"	"4"	"2"	"429"	"47.4"	"5.60"	"744.74"	"8.61"	"2"	"2"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00022"	"86"	"ENSG00000136518"	"ACTL6A"	"B3KMN1; D3DNR9; hsa:86; O96019; Q8TAE5; Q9BVS8; Q9H0W6"	"Androgen receptor network in prostate cancer; Gastric cancer network 1; Tumor suppressor activity of SMARCB1; Thermogenesis; Kleefstra syndrome"	"RMTs methylate histone arginines; UCH proteinases; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; HATs acetylate histones; DNA Damage Recognition in GG-NER"	"10"	"0"	"53.4"	"42.3"	"60.2"	"55.6"	"53.2"	"52.0"	"69.9"	"130.2"	"123.8"	"293.0"	"484.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z406"	"Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2"	"0.000"	""	"2"	"3"	"4"	"1"	"1995"	"227.7"	"5.60"	"441.23"	"8.59"	"1"	"3"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00063, Pf01576, Pf02736"	"79784"	"ENSG00000105357"	"MYH14"	"B0I1S2; C3TTN4; hsa:79784; Q5CZ75; Q6XYE4; Q76B62; Q7Z406; Q8WV23; Q96I22; Q9BT27; Q9BW35; Q9H882"	""	"RHO GTPases activate CIT; RHO GTPases activate PKNs; RHO GTPases activate PAKs; EPHA-mediated growth cone collapse; Sema4D induced cell migration and growth-cone collapse; RHO GTPases Activate ROCKs"	"6"	"0"	"84.9"	"28.0"	"117.7"	"92.5"	"91.9"	"105.3"	"122.9"	"179.5"	"200.6"	"335.4"	"334.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16891"	"MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1"	"0.000"	""	"6"	"4"	"6"	"4"	"758"	"83.6"	"6.48"	"928.70"	"8.59"	"3"	"3"	"cell organization and biogenesis;other biological processes"	"other membranes;mitochondrion"	""	"Pf09731"	"10989"	"ENSG00000132305"	"IMMT"	"B1H0U5; B2R5N6; hsa:10989; Q14539; Q15092; Q16891; Q68D41; Q69HW5; Q6IBL0; Q7Z3X1; Q8TAJ5; Q9P0V2"	""	"Cristae formation"	"1"	"0"	"214.8"	"170.2"	"219.0"	"191.4"	"202.6"	"205.1"	"246.9"	"521.8"	"537.7"	"1262.7"	"1790.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6W5"	"Wiskott-Aldrich syndrome protein family member 2 OS=Homo sapiens OX=9606 GN=WASF2 PE=1 SV=3"	"0.000"	""	"5"	"2"	"4"	"1"	"498"	"54.3"	"5.53"	"910.75"	"8.59"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02205"	"10163"	"ENSG00000158195"	"WASF2"	"B4DZN0; hsa:10163; O60794; Q9UDY7; Q9Y6W5"	"Regulation of actin cytoskeleton"	"RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; VEGFA-VEGFR2 Pathway"	"8"	"0"	"17.8"	"10.6"	"11.2"	"17.7"	"12.3"	"12.6"	"17.2"	"46.8"	"43.4"	"76.6"	"72.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVX2"	"Notchless protein homolog 1 OS=Homo sapiens OX=9606 GN=NLE1 PE=1 SV=4"	"0.000"	""	"7"	"2"	"3"	"2"	"485"	"53.3"	"7.34"	"336.62"	"8.58"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"nucleus"	""	"Pf00400, Pf08154"	"54475"	"ENSG00000073536"	"NLE1"	"hsa:54475; O60868; Q59GJ8; Q9BU54; Q9NVX2"	"17q12 copy number variation syndrome"	""	"1"	"0"	"27.2"	"22.9"	"32.6"	"30.8"	"23.7"	"27.2"	"38.7"	"74.0"	"77.3"	"210.2"	"262.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HC52"	"Chromobox protein homolog 8 OS=Homo sapiens OX=9606 GN=CBX8 PE=1 SV=3"	"0.000"	""	"8"	"2"	"4"	"2"	"389"	"43.4"	"9.91"	"703.01"	"8.57"	"2"	"2"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00385, Pf17218"	"57332"	"ENSG00000141570"	"CBX8"	"hsa:57332; Q96H39; Q9HC52; Q9NR07"	""	"SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Oxidative Stress Induced Senescence; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Regulation of PTEN gene transcription"	"8"	"0"	"83.6"	"91.8"	"78.3"	"71.9"	"89.5"	"82.8"	"99.9"	"150.5"	"163.4"	"379.3"	"601.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BYD3"	"39S ribosomal protein L4, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL4 PE=1 SV=1"	"0.000"	""	"9"	"2"	"4"	"2"	"311"	"34.9"	"9.72"	"867.49"	"8.56"	"2"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00573"	"51073"	"ENSG00000105364"	"MRPL4"	"A6NNV7; hsa:51073; Q9BW07; Q9BYD3; Q9H4N2; Q9Y317"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"87.7"	"50.4"	"124.1"	"86.2"	"79.9"	"92.1"	"118.4"	"236.2"	"218.7"	"570.9"	"949.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IWS0"	"PHD finger protein 6 OS=Homo sapiens OX=9606 GN=PHF6 PE=1 SV=1"	"0.000"	""	"9"	"2"	"3"	"2"	"365"	"41.3"	"8.68"	"389.14"	"8.55"	"1"	"2"	"developmental processes;other biological processes"	"nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf13771"	"84295"	"ENSG00000156531"	"PHF6"	"A8K230; B4E0G4; D3DTG3; E9PC97; hsa:84295; Q5JRC7; Q5JRC8; Q8IWS0; Q96JK3; Q9BRU0"	"Mesodermal commitment pathway"	""	"1"	"0"	"80.2"	"56.4"	"69.1"	"75.8"	"66.4"	"61.1"	"105.0"	"175.8"	"168.2"	"278.7"	"275.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NQ50"	"39S ribosomal protein L40, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL40 PE=1 SV=1"	"0.000"	""	"16"	"2"	"4"	"2"	"206"	"24.5"	"9.63"	"1125.42"	"8.52"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	""	"Pf09812"	"64976"	"ENSG00000185608"	"MRPL40"	"B3KVZ7; hsa:64976; O95134; Q9NQ50"	"22q11.2 copy number variation syndrome"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"4"	"0"	"56.0"	"48.2"	"74.8"	"47.9"	"66.4"	"73.8"	"88.2"	"98.4"	"94.1"	"167.0"	"223.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P41223"	"Protein BUD31 homolog OS=Homo sapiens OX=9606 GN=BUD31 PE=1 SV=2"	"0.000"	""	"21"	"4"	"6"	"4"	"144"	"17.0"	"8.82"	"1766.09"	"8.51"	"4"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf01125"	"8896"	"ENSG00000106245"	"BUD31"	"A4D274; B7Z4S9; D6W5S6; hsa:8896; P41223; Q6IB53; Q9UDV1"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"195.3"	"172.0"	"207.7"	"167.3"	"205.3"	"192.8"	"248.5"	"385.6"	"345.3"	"667.5"	"971.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6GYQ0"	"Ral GTPase-activating protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=RALGAPA1 PE=1 SV=1"	"0.000"	""	"2"	"3"	"5"	"3"	"2036"	"229.7"	"6.19"	"960.09"	"8.51"	"3"	"2"	"other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02145, Pf20412"	"253959"	"ENSG00000174373"	"RALGAPA1"	"A6NMA4; B9EK38; C5NU19; hsa:253959; O94960; Q6GYP9; Q6GYQ0; Q6ZT23; Q86YF3; Q86YF5; Q8ND69"	""	"RHOH GTPase cycle"	"1"	"0"	"79.2"	"54.1"	"96.1"	"85.0"	"81.0"	"103.4"	"140.3"	"387.0"	"380.9"	"739.0"	"807.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96CP2"	"FLYWCH family member 2 OS=Homo sapiens OX=9606 GN=FLYWCH2 PE=1 SV=1"	"0.000"	""	"19"	"2"	"4"	"2"	"140"	"14.6"	"8.46"	"788.61"	"8.50"	"2"	"2"	""	""	""	"Pf15423"	"114984"	"ENSG00000162076"	"FLYWCH2"	"hsa:114984; Q96CP2"	""	""	"0"	"0"	"66.9"	"59.4"	"73.9"	"60.7"	"64.1"	"58.7"	"81.9"	"286.0"	"289.8"	"656.9"	"876.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2R9"	"28S ribosomal protein S7, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS7 PE=1 SV=2"	"0.000"	""	"10"	"2"	"4"	"2"	"242"	"28.1"	"9.99"	"805.63"	"8.48"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00177"	"51081"	"ENSG00000125445"	"MRPS7"	"B2R9N5; hsa:51081; Q53GD6; Q9Y2R9"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"100.4"	"81.0"	"110.2"	"111.9"	"98.6"	"97.1"	"139.4"	"214.3"	"207.2"	"390.9"	"527.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43427"	"Acidic fibroblast growth factor intracellular-binding protein OS=Homo sapiens OX=9606 GN=FIBP PE=1 SV=3"	"0.000"	""	"9"	"4"	"7"	"4"	"364"	"41.9"	"6.48"	"1134.31"	"8.46"	"4"	"3"	"signal transduction"	"other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf05427"	"9158"	"ENSG00000172500"	"FIBP"	"A8K0J7; hsa:9158; O43427; Q27Q85; Q6IBQ3; Q9HD65"	"Modulators of TCR signaling and T cell activation"	""	"1"	"0"	"80.9"	"65.9"	"102.1"	"88.3"	"102.8"	"244.2"	"505.6"	"1145.0"	"1207.9"	"1783.9"	"1909.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H9Q2"	"COP9 signalosome complex subunit 7b OS=Homo sapiens OX=9606 GN=COPS7B PE=1 SV=1"	"0.000"	""	"9"	"2"	"4"	"2"	"264"	"29.6"	"6.15"	"697.87"	"8.46"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf01399, Pf18392"	"64708"	"ENSG00000144524"	"COPS7B"	"hsa:64708; Q53S22; Q5BJG3; Q9H7V6; Q9H9Q2"	"Ciliary landscape"	"Neddylation; Formation of TC-NER Pre-Incision Complex; Cargo recognition for clathrin-mediated endocytosis; DNA Damage Recognition in GG-NER"	"5"	"0"	"22.9"	"16.7"	"21.2"	"23.3"	"26.6"	"27.9"	"31.9"	"93.1"	"81.2"	"262.4"	"462.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NXE4"	"Sphingomyelin phosphodiesterase 4 OS=Homo sapiens OX=9606 GN=SMPD4 PE=1 SV=3"	""	""	"3"	"1"	"2"	"1"	"866"	"97.7"	"8.27"	""	"8.44"	""	"1"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus"	"other molecular function"	"Pf14724"	"55627"	"ENSG00000136699"	"SMPD4"	"B1PBA3; B4DM23; B4DQ31; B4DRB8; B4DWK7; B4E0L6; E7ESA2; E9PCE6; hsa:55627; Q6FI76; Q6P1P7; Q6ZT43; Q9H0M2; Q9NW20; Q9NWL2; Q9NXE4; Q9P2C9"	""	"Glycosphingolipid metabolism"	"1"	"0"	"5.1"	"4.5"	"8.1"	"3.9"	"5.9"	"7.1"	"9.9"	"13.8"	"17.1"	"33.7"	"45.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q969G3"	"SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Homo sapiens OX=9606 GN=SMARCE1 PE=1 SV=2"	"0.000"	""	"6"	"2"	"4"	"2"	"411"	"46.6"	"4.88"	"787.51"	"8.42"	"2"	"2"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00505"	"6605"	"ENSG00000073584"	"SMARCE1"	"B3KMC1; B4DFR4; C0IMW4; C0IMW5; C0IMW7; H7C3F6; hsa:6605; O43539; Q969G3"	"Androgen receptor signaling pathway; Pathways affected in adenoid cystic carcinoma; Tumor suppressor activity of SMARCB1; Thermogenesis"	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; RMTs methylate histone arginines"	"6"	"0"	"80.9"	"67.3"	"89.8"	"91.0"	"69.8"	"78.1"	"103.6"	"191.8"	"173.2"	"436.0"	"617.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99417"	"c-Myc-binding protein OS=Homo sapiens OX=9606 GN=MYCBP PE=1 SV=3"	"0.000"	""	"30"	"2"	"3"	"2"	"103"	"12.0"	"5.91"	"657.51"	"8.41"	"1"	"2"	"other biological processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	""	"26292"	"ENSG00000214114"	"MYCBP"	"B2R4N0; hsa:26292; Q5TA64; Q96HE2; Q99417"	"Pathways affected in adenoid cystic carcinoma"	""	"1"	"0"	"10.3"	"11.9"	"10.8"	"19.3"	"18.5"	"18.9"	"23.1"	"104.0"	"107.5"	"273.3"	"503.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UPY6"	"Wiskott-Aldrich syndrome protein family member 3 OS=Homo sapiens OX=9606 GN=WASF3 PE=1 SV=2"	"0.000"	""	"5"	"2"	"4"	"1"	"502"	"55.3"	"6.43"	"921.32"	"8.39"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02205"	"10810"	"ENSG00000132970"	"WASF3"	"hsa:10810; O94974; Q86VQ2; Q9UPY6"	""	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; RAC1 GTPase cycle; VEGFA-VEGFR2 Pathway"	"5"	"1"	"18.4"	"21.2"	"17.5"	"19.5"	"19.5"	"16.6"	"23.9"	"58.9"	"62.7"	"104.1"	"142.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13492"	"Phosphatidylinositol-binding clathrin assembly protein OS=Homo sapiens OX=9606 GN=PICALM PE=1 SV=2"	"0.000"	""	"6"	"3"	"5"	"3"	"652"	"70.7"	"7.90"	"1350.56"	"8.37"	"3"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf07651"	"8301"	"ENSG00000073921"	"PICALM"	"B4DTM3; E9PN05; F8VPG7; hsa:8301; O60700; Q13492; Q4LE54; Q6GMQ6; Q86XZ9"	""	"Cargo recognition for clathrin-mediated endocytosis; Golgi Associated Vesicle Biogenesis; RND3 GTPase cycle"	"4"	"0"	"146.5"	"116.5"	"138.3"	"116.1"	"133.1"	"168.1"	"212.9"	"444.0"	"436.2"	"809.4"	"983.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UNY4"	"Transcription termination factor 2 OS=Homo sapiens OX=9606 GN=TTF2 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"1162"	"129.5"	"8.37"	"935.56"	"8.36"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf06839"	"8458"	"ENSG00000116830"	"TTF2"	"A8K4Q2; hsa:8458; O75921; Q5T2K7; Q5VVU8; Q8N6I8; Q9UNY4"	"Thyroid stimulating hormone (TSH) signaling pathway; Thyroid hormones production and peripheral downstream signaling effects"	""	"2"	"0"	"84.8"	"84.6"	"88.8"	"84.4"	"88.1"	"84.0"	"109.8"	"202.1"	"196.9"	"446.5"	"545.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14950"	"Myosin regulatory light chain 12B OS=Homo sapiens OX=9606 GN=MYL12B PE=1 SV=2"	"0.000"	""	"23"	"3"	"5"	"3"	"172"	"19.8"	"4.84"	"1285.58"	"8.35"	"3"	"2"	"other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf08976, Pf13405"	"103910; 10627"	"ENSG00000118680"	"MYL12B"	"D3DUH6; hsa:103910; O14950; Q13182; Q7Z5Z4"	"Thyroid stimulating hormone (TSH) signaling pathway; Focal adhesion"	"RHO GTPases activate CIT; EPHA-mediated growth cone collapse; Sema4D induced cell migration and growth-cone collapse; Smooth Muscle Contraction; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; RHO GTPases activate PAKs"	"9"	"0"	"186.8"	"122.0"	"188.1"	"167.8"	"172.6"	"173.8"	"236.2"	"434.3"	"392.3"	"1645.0"	"3131.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5T4S7"	"E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens OX=9606 GN=UBR4 PE=1 SV=1"	"0.000"	""	"1"	"2"	"3"	"2"	"5183"	"573.5"	"6.04"	"337.81"	"8.35"	"1"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus"	"other molecular function"	"Pf02207, Pf13764, Pf19423"	"23352"	"ENSG00000127481"	"UBR4"	"A8MPT2; A8MQ33; A8MQB1; hsa:23352; O60646; O75050; Q4QRK5; Q5T4S7; Q5T4S8; Q5T4S9; Q5TBN8; Q5TBP2; Q6DKH8; Q6P4A4; Q7L8P7; Q8IXJ4; Q8TDN5; Q8WV67; Q9HA46; Q9P2N9; Q9UG82"	""	"Antigen processing: Ubiquitination & Proteasome degradation; Neutrophil degranulation"	"2"	"0"	"27.1"	"21.0"	"25.7"	"25.0"	"28.1"	"32.3"	"38.4"	"55.5"	"58.0"	"118.2"	"138.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99961"	"Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1"	"0.000"	""	"7"	"2"	"4"	"2"	"368"	"41.5"	"5.43"	"750.64"	"8.34"	"2"	"2"	"cell organization and biogenesis;transport;developmental processes;signal transduction"	"other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00018, Pf03114"	"6455"	"ENSG00000141985"	"SH3GL1"	"B4DRA1; E7EVZ4; hsa:6455; M0QZV5; Q99668; Q99961"	"Fragile X syndrome"	"Cargo recognition for clathrin-mediated endocytosis; EGFR downregulation; Negative regulation of MET activity; InlB-mediated entry of Listeria monocytogenes into host cell"	"6"	"0"	"29.7"	"21.5"	"43.2"	"47.3"	"37.2"	"34.8"	"46.5"	"101.1"	"95.8"	"372.9"	"821.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62266"	"40S ribosomal protein S23 OS=Homo sapiens OX=9606 GN=RPS23 PE=1 SV=3"	"0.000"	""	"8"	"1"	"4"	"1"	"143"	"15.8"	"10.49"	"899.45"	"8.31"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00164"	"6228"	"ENSG00000186468"	"RPS23"	"hsa:6228; P39028; P62266; Q6IB08"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"171.8"	"150.7"	"134.4"	"131.7"	"140.4"	"161.1"	"214.5"	"392.9"	"370.8"	"933.5"	"1531.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15047"	"Histone-lysine N-methyltransferase SETD1A OS=Homo sapiens OX=9606 GN=SETD1A PE=1 SV=3"	"0.000"	""	"2"	"2"	"4"	"2"	"1707"	"185.9"	"5.14"	"765.29"	"8.31"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00856, Pf11764"	"9739"	"ENSG00000099381"	"SETD1A"	"A6NP62; hsa:9739; O15047; Q6PIF3; Q8TAJ6"	"Histone modifications"	"Formation of WDR5-containing histone-modifying complexes; PKMTs methylate histone lysines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"	"4"	"0"	"23.8"	"20.5"	"28.3"	"22.9"	"25.8"	"24.0"	"33.4"	"47.0"	"45.7"	"101.4"	"172.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92796"	"Disks large homolog 3 OS=Homo sapiens OX=9606 GN=DLG3 PE=1 SV=2"	"0.000"	""	"5"	"2"	"3"	"2"	"817"	"90.3"	"7.03"	"531.79"	"8.31"	"1"	"2"	"cell-cell signaling;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00018, Pf00595, Pf00625, Pf10600"	"1741"	"ENSG00000082458"	"DLG3"	"B4E0H1; D3DVU5; hsa:1741; Q5JUW6; Q5JUW7; Q92796; Q9ULI8"	""	"Assembly and cell surface presentation of NMDA receptors; RAF/MAP kinase cascade; Neurexins and neuroligins; Ras activation upon Ca2+ influx through NMDA receptor; Unblocking of NMDA receptors, glutamate binding and activation; Synaptic adhesion-like molecules; Negative regulation of NMDA receptor-mediated neuronal transmission; Long-term potentiation; NrCAM interactions; Activation of Ca-permeable Kainate Receptor"	"10"	"0"	"44.7"	"21.1"	"49.8"	"46.8"	"44.1"	"41.2"	"56.3"	"114.1"	"119.2"	"232.8"	"267.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NY61"	"Protein AATF OS=Homo sapiens OX=9606 GN=AATF PE=1 SV=1"	"0.000"	""	"7"	"2"	"3"	"2"	"560"	"63.1"	"4.94"	"386.21"	"8.30"	"1"	"2"	"cell adhesion;stress response;developmental processes;other biological processes"	"ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf08164, Pf13339"	"26574"	"ENSG00000275700; ENSG00000276072"	"AATF"	"A6NCJ6; B3KQ26; hsa:26574; Q9NY61; Q9P0A4; Q9UNX5"	"17q12 copy number variation syndrome"	"NRAGE signals death through JNK"	"2"	"0"	"33.0"	"26.0"	"40.1"	"32.6"	"29.7"	"31.4"	"39.7"	"80.5"	"88.7"	"208.2"	"307.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6NZY4"	"Zinc finger CCHC domain-containing protein 8 OS=Homo sapiens OX=9606 GN=ZCCHC8 PE=1 SV=2"	"0.000"	""	"4"	"2"	"4"	"2"	"707"	"78.5"	"4.87"	"845.11"	"8.28"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00098, Pf04046"	"55596"	"ENSG00000033030"	"ZCCHC8"	"hsa:55596; Q6NZY4; Q7L2P6; Q8N2K5; Q96SK7; Q9NSS2; Q9NSS3"	""	""	"0"	"0"	"152.5"	"153.0"	"159.1"	"147.9"	"130.1"	"133.0"	"178.5"	"236.3"	"192.0"	"389.3"	"556.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BTD8"	"RNA-binding protein 42 OS=Homo sapiens OX=9606 GN=RBM42 PE=1 SV=1"	"0.000"	""	"7"	"4"	"7"	"4"	"480"	"50.4"	"9.63"	"1139.53"	"8.25"	"4"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"79171"	"ENSG00000126254"	"RBM42"	"hsa:79171; O00320; Q8N5R7; Q9BTD8; Q9BU66"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"626.9"	"485.2"	"452.1"	"464.7"	"403.3"	"420.8"	"572.5"	"888.1"	"849.7"	"1668.8"	"2409.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y617"	"Phosphoserine aminotransferase OS=Homo sapiens OX=9606 GN=PSAT1 PE=1 SV=2"	""	""	"9"	"2"	"2"	"2"	"370"	"40.4"	"7.66"	""	"8.25"	""	"2"	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00266"	"29968"	"ENSG00000135069"	"PSAT1"	"hsa:29968; Q5T7G5; Q5T7G6; Q96AW2; Q9BQ12; Q9Y617"	"Trans-sulfuration, one-carbon metabolism and related pathways; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Male infertility; Neuroinflammation and glutamatergic signaling; Amino acid metabolism in triple-negative breast cancer cells"	"Serine biosynthesis"	"7"	"0"	"24.6"	"17.5"	"38.5"	"32.6"	"29.2"	"25.6"	"34.5"	"64.0"	"67.7"	"169.4"	"583.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P84098"	"60S ribosomal protein L19 OS=Homo sapiens OX=9606 GN=RPL19 PE=1 SV=1"	"0.000"	""	"17"	"4"	"6"	"3"	"196"	"23.5"	"11.47"	"1352.02"	"8.22"	"4"	"2"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01280"	"6143"	"ENSG00000108298"	"RPL19"	"B2R4K2; hsa:6143; P14118; P22908; P84098; Q502Y6; Q7Z6E4"	"Cytoplasmic ribosomal proteins"	"Major pathway of rRNA processing in the nucleolus and cytosol; Regulation of expression of SLITs and ROBOs; SRP-dependent cotranslational protein targeting to membrane; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"163.0"	"150.1"	"172.5"	"140.5"	"158.6"	"176.4"	"197.1"	"257.9"	"280.8"	"525.2"	"706.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62834"	"Ras-related protein Rap-1A OS=Homo sapiens OX=9606 GN=RAP1A PE=1 SV=1"	"0.000"	""	"15"	"2"	"3"	"2"	"184"	"21.0"	"6.67"	"548.93"	"8.21"	"1"	"2"	"cell-cell signaling;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00071"	"5906"	"ENSG00000116473"	"RAP1A"	"hsa:5906; P10113; P62834"	"Integrin-mediated cell adhesion; Thyroid stimulating hormone (TSH) signaling pathway; Androgen receptor network in prostate cancer; Brain-derived neurotrophic factor (BDNF) signaling pathway; Common pathways underlying drug addiction; Focal adhesion; Hepatocyte growth factor receptor signaling; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Ras signaling; EGF/EGFR signaling pathway; Leukocyte-intrinsic Hippo pathway functions; DNA repair pathways, full network; GDNF signaling; Interferon type I signaling pathways; Serotonin HTR1 group and FOS pathway; Serotonin receptor 4/6/7 and NR3C signaling"	"Neutrophil degranulation; Signaling by BRAF and RAF1 fusions; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; Rap1 signalling; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; Frs2-mediated activation; ARMS-mediated activation; GRB2:SOS provides linkage to MAPK signaling for Integrins ; p130Cas linkage to MAPK signaling for integrins; MET activates RAP1 and RAC1"	"34"	"0"	"115.2"	"91.9"	"97.8"	"97.3"	"94.3"	"87.5"	"152.9"	"236.1"	"276.9"	"479.5"	"559.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H6R4"	"Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2"	"0.000"	""	"2"	"2"	"4"	"2"	"1146"	"127.5"	"7.64"	"933.40"	"8.20"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"mitochondrion;nucleus;other cell component"	""	"Pf03813, Pf17403, Pf17404, Pf17405, Pf17406, Pf17407"	"65083"	"ENSG00000165271"	"NOL6"	"hsa:65083; Q5T5M3; Q5T5M4; Q7L4G6; Q8N6I0; Q8TEY9; Q8TEZ0; Q8TEZ1; Q9H675; Q9H6R4"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"79.2"	"50.5"	"71.7"	"74.0"	"65.0"	"74.8"	"99.2"	"221.1"	"248.5"	"556.8"	"761.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62191"	"26S proteasome regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMC1 PE=1 SV=1"	"0.000"	""	"4"	"2"	"4"	"2"	"440"	"49.2"	"6.21"	"833.37"	"8.19"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf16450, Pf17862"	"5700"	"ENSG00000100764"	"PSMC1"	"B4DR63; hsa:5700; P49014; P62191; Q03527; Q6IAW0; Q6NW36; Q96AZ3"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; N-glycan trimming in the ER and Calnexin/Calreticulin cycle"	"64"	"0"	"69.3"	"46.8"	"92.7"	"84.4"	"71.0"	"70.2"	"83.5"	"136.6"	"137.1"	"319.8"	"490.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BT09"	"Protein canopy homolog 3 OS=Homo sapiens OX=9606 GN=CNPY3 PE=1 SV=1"	"0.000"	""	"11"	"2"	"4"	"2"	"278"	"30.7"	"5.49"	"855.94"	"8.19"	"2"	"2"	"stress response"	"ER/Golgi"	"signal transduction activity or receptor binding"	"Pf11938"	"10695"	"ENSG00000137161"	"CNPY3"	"hsa:10695; O15412; Q0P6I2; Q8NF54; Q8WTU8; Q9BT09; Q9P0F2"	""	"Trafficking and processing of endosomal TLR"	"1"	"0"	"13.5"	"13.2"	"15.4"	"14.0"	"16.1"	"15.2"	"19.6"	"218.9"	"234.2"	"529.8"	"595.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14531"	"Dihydropyrimidinase-related protein 4 OS=Homo sapiens OX=9606 GN=DPYSL4 PE=1 SV=2"	"0.000"	""	"6"	"3"	"6"	"3"	"572"	"61.8"	"7.09"	"1025.65"	"8.17"	"3"	"3"	"developmental processes"	"cytosol"	"cytoskeletal activity;other molecular function"	"Pf01979"	"10570"	"ENSG00000151640"	"DPYSL4"	"B2RMQ1; D3DRG5; hsa:10570; O00240; O14531; Q5T0Q7"	""	"CRMPs in Sema3A signaling"	"1"	"0"	"23.5"	"24.6"	"29.4"	"24.6"	"22.3"	"23.5"	"24.6"	"128.1"	"154.4"	"750.7"	"1133.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BWJ5"	"Splicing factor 3B subunit 5 OS=Homo sapiens OX=9606 GN=SF3B5 PE=1 SV=1"	"0.000"	""	"17"	"1"	"4"	"1"	"86"	"10.1"	"6.35"	"779.72"	"8.14"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf07189"	"83443"	"ENSG00000169976"	"SF3B5"	"B2R568; hsa:83443; Q7RTV1; Q9BWJ5"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"3"	"0"	"108.7"	"86.7"	"119.8"	"119.0"	"110.6"	"97.4"	"139.1"	"200.2"	"191.5"	"401.9"	"637.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HCC0"	"Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC2 PE=1 SV=1"	"0.000"	""	"8"	"5"	"8"	"5"	"563"	"61.3"	"7.68"	"2062.72"	"8.12"	"5"	"3"	"other metabolic processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf01039"	"64087"	"ENSG00000131844"	"MCCC2"	"A6NIY9; hsa:64087; Q96C27; Q9HCC0; Q9Y4L7"	""	"Biotin transport and metabolism; Branched-chain amino acid catabolism; Defective HLCS causes multiple carboxylase deficiency"	"3"	"0"	"513.0"	"569.3"	"345.2"	"416.9"	"370.9"	"397.1"	"527.1"	"746.4"	"654.8"	"1217.8"	"1553.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19784"	"Casein kinase II subunit alpha' OS=Homo sapiens OX=9606 GN=CSNK2A2 PE=1 SV=1"	"0.000"	""	"9"	"3"	"5"	"3"	"350"	"41.2"	"8.56"	"682.21"	"8.12"	"2"	"3"	"cell-cell signaling;cell cycle OR cell proliferation;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"1459"	"ENSG00000070770"	"CSNK2A2"	"hsa:1459; P19784"	"Alzheimer's disease and miRNA effects; Allograft rejection; lncRNA in canonical Wnt signaling and colorectal cancer; Breast cancer pathway; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Measles virus infection; Pleural mesothelioma; Alzheimer's disease"	"Regulation of PTEN stability and activity; KEAP1-NFE2L2 pathway; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Regulation of TP53 Activity through Phosphorylation; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; WNT mediated activation of DVL; Signal transduction by L1; Receptor Mediated Mitophagy; Condensation of Prometaphase Chromosomes; Synthesis of PC"	"19"	"0"	"149.5"	"131.5"	"148.8"	"120.1"	"125.5"	"135.8"	"168.9"	"317.0"	"297.5"	"771.8"	"1227.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y333"	"U6 snRNA-associated Sm-like protein LSm2 OS=Homo sapiens OX=9606 GN=LSM2 PE=1 SV=1"	"0.000"	""	"29"	"2"	"4"	"2"	"95"	"10.8"	"6.52"	"856.78"	"8.12"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01423"	"57819"	"ENSG00000172850; ENSG00000204392; ENSG00000224979; ENSG00000225998; ENSG00000231502; ENSG00000236826"	"LSM2"	"hsa:57819; Q6FGG1; Q9Y333"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA decay by 5' to 3' exoribonuclease"	"3"	"0"	"193.7"	"179.8"	"173.0"	"177.6"	"174.4"	"171.4"	"202.7"	"325.0"	"264.0"	"712.9"	"1553.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16352"	"Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2"	"0.000"	""	"8"	"4"	"6"	"2"	"499"	"55.4"	"5.40"	"1214.26"	"8.10"	"3"	"3"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf00038, Pf04732"	"9118"	"ENSG00000148798"	"INA"	"B1AQK0; hsa:9118; Q16352; Q9BRC5"	""	""	"0"	"0"	"124.2"	"77.1"	"118.7"	"95.0"	"84.6"	"88.8"	"138.7"	"298.2"	"266.0"	"704.0"	"1095.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P1U0"	"DNA-directed RNA polymerase I subunit RPA12 OS=Homo sapiens OX=9606 GN=ZNRD1 PE=1 SV=1"	"0.000"	""	"19"	"2"	"3"	"2"	"126"	"13.9"	"5.06"	"292.33"	"8.05"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01096"	"30834"	"ENSG00000066379; ENSG00000206502; ENSG00000224859; ENSG00000233795; ENSG00000235176; ENSG00000235443; ENSG00000236808; ENSG00000236949"	"POLR1H"	"hsa:30834; Q9P1U0"	"Pyrimidine metabolism; 2q13 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"7"	"0"	"84.5"	"51.5"	"82.6"	"89.3"	"78.0"	"84.4"	"96.6"	"407.2"	"416.5"	"881.8"	"1048.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P16989"	"Y-box-binding protein 3 OS=Homo sapiens OX=9606 GN=YBX3 PE=1 SV=4"	"0.000"	""	"12"	"3"	"5"	"1"	"372"	"40.1"	"9.77"	"964.96"	"8.05"	"3"	"2"	"stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00313"	"8531"	"ENSG00000060138"	"YBX3"	"B2RBW6; hsa:8531; P16989; Q14121; Q969N6; Q96B76"	"RalA downstream regulated genes; Apoptosis-related network due to altered Notch3 in ovarian cancer"	""	"2"	"0"	"13.6"	"9.9"	"15.8"	"15.2"	"19.0"	"12.7"	"13.5"	"23.3"	"30.4"	"50.0"	"57.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52756"	"RNA-binding protein 5 OS=Homo sapiens OX=9606 GN=RBM5 PE=1 SV=2"	"0.000"	""	"6"	"4"	"6"	"4"	"815"	"92.1"	"6.28"	"1588.65"	"8.05"	"4"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00641, Pf01585, Pf17780"	"10181"	"ENSG00000003756"	"RBM5"	"B2RA45; B4DM16; B4DMF9; B4DZ63; hsa:10181; P52756; Q93021; Q9BU14; Q9HDA6; Q9UKY8; Q9UL24"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"315.9"	"260.4"	"308.4"	"288.3"	"284.8"	"249.5"	"353.3"	"446.5"	"451.5"	"808.9"	"1150.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3C1"	"Nucleolar protein 16 OS=Homo sapiens OX=9606 GN=NOP16 PE=1 SV=2"	"0.000"	""	"9"	"1"	"4"	"1"	"178"	"21.2"	"9.94"	"824.50"	"8.04"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	""	"Pf09420"	"51491"	"ENSG00000048162"	"NOP16"	"B4DV13; D6RGD3; hsa:51491; Q05D05; Q6IAI6; Q6PIM0; Q8IXL5; Q9Y3C1"	"5q35 copy number variation"	""	"1"	"0"	"73.1"	"70.5"	"67.5"	"71.6"	"75.2"	"79.6"	"100.6"	"157.1"	"162.8"	"291.3"	"396.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96RN5"	"Mediator of RNA polymerase II transcription subunit 15 OS=Homo sapiens OX=9606 GN=MED15 PE=1 SV=2"	"0.000"	""	"2"	"1"	"4"	"1"	"788"	"86.7"	"9.42"	"981.41"	"8.02"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf09606"	"51586"	"ENSG00000099917"	"MED15"	"D3DX31; D3DX32; hsa:51586; O15413; Q6IC31; Q8NF16; Q96CT0; Q96IH7; Q96RN5; Q9P1T3"	"Sterol regulatory element-binding proteins (SREBP) signaling; SREBF and miR33 in cholesterol and lipid homeostasis; 22q11.2 copy number variation syndrome"	"PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; Generic Transcription Pathway"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BQA1"	"Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1"	"0.000"	""	"9"	"3"	"5"	"3"	"342"	"36.7"	"5.17"	"587.37"	"8.02"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400"	"79084"	"ENSG00000116455"	"WDR77"	"B3KMW6; B4DP38; hsa:79084; Q3LID2; Q53FU2; Q6JZZ5; Q96GK4; Q9BQA1; Q9BWY3"	""	"snRNP Assembly; RMTs methylate histone arginines"	"2"	"0"	"77.7"	"46.7"	"89.2"	"63.0"	"61.1"	"65.6"	"95.3"	"199.9"	"159.6"	"538.3"	"897.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14677"	"Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1"	"0.000"	""	"5"	"3"	"6"	"3"	"625"	"68.2"	"6.42"	"827.75"	"8.02"	"3"	"3"	"transport"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01417"	"9685"	"ENSG00000113282"	"CLINT1"	"B7Z6F8; D3DQJ6; hsa:9685; Q14677; Q8NAF1; Q96E05"	""	"Golgi Associated Vesicle Biogenesis"	"1"	"0"	"304.6"	"214.6"	"289.4"	"285.8"	"262.8"	"282.5"	"335.2"	"566.4"	"552.4"	"1267.5"	"1847.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94776"	"Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1"	"0.000"	""	"5"	"2"	"4"	"2"	"668"	"75.0"	"9.66"	"789.08"	"8.01"	"2"	"2"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00320, Pf01426, Pf01448, Pf17226"	"9219"	"ENSG00000149480"	"MTA2"	"hsa:9219; O94776; Q68DB1; Q9UQB5"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"Potential therapeutics for SARS; Regulation of PTEN gene transcription; HDACs deacetylate histones; RNA Polymerase I Transcription Initiation; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of TP53 Activity through Acetylation"	"7"	"0"	"90.0"	"66.7"	"91.9"	"92.1"	"78.9"	"95.3"	"119.3"	"179.1"	"195.3"	"408.7"	"510.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96IZ0"	"PRKC apoptosis WT1 regulator protein OS=Homo sapiens OX=9606 GN=PAWR PE=1 SV=1"	"0.000"	""	"11"	"2"	"3"	"2"	"340"	"36.5"	"5.41"	"420.66"	"8.01"	"1"	"2"	"cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	""	"5074"	"ENSG00000177425"	"PAWR"	"hsa:5074; O75796; Q6FHY9; Q8N700; Q96IZ0"	""	""	"0"	"0"	"27.2"	"18.0"	"29.2"	"23.9"	"24.7"	"28.3"	"24.7"	"73.9"	"79.5"	"219.2"	"222.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N5K1"	"CDGSH iron-sulfur domain-containing protein 2 OS=Homo sapiens OX=9606 GN=CISD2 PE=1 SV=1"	"0.000"	""	"21"	"2"	"4"	"2"	"135"	"15.3"	"9.61"	"776.29"	"8.00"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"other membranes;mitochondrion;ER/Golgi;other cell component"	"other molecular function"	"Pf09360, Pf10660"	"493856"	"ENSG00000145354"	"CISD2"	"hsa:493856; Q7Z3D5; Q8N5K1"	""	""	"0"	"0"	"36.6"	"33.3"	"45.8"	"47.0"	"36.3"	"40.0"	"47.0"	"161.0"	"180.2"	"405.0"	"552.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14795"	"Protein unc-13 homolog B OS=Homo sapiens OX=9606 GN=UNC13B PE=1 SV=2"	"0.000"	""	"3"	"4"	"6"	"4"	"1591"	"180.6"	"5.99"	"1757.34"	"7.99"	"4"	"2"	"cell-cell signaling;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00130, Pf00168, Pf06292"	"10497"	"ENSG00000198722"	"UNC13B"	"hsa:10497; O14795; Q2NKJ5; Q5VYM8"	"Synaptic vesicle pathway; 16p11.2 proximal deletion syndrome; Monoamine transport"	"Glutamate Neurotransmitter Release Cycle; Serotonin Neurotransmitter Release Cycle; Norepinephrine Neurotransmitter Release Cycle; Dopamine Neurotransmitter Release Cycle; Acetylcholine Neurotransmitter Release Cycle"	"8"	"0"	"64.5"	"47.5"	"70.4"	"60.8"	"66.0"	"96.6"	"146.3"	"417.5"	"478.8"	"677.8"	"659.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6UB35"	"Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1"	"0.000"	""	"3"	"2"	"4"	"2"	"978"	"105.7"	"8.06"	"771.06"	"7.95"	"2"	"2"	"other metabolic processes;developmental processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf00763, Pf01268, Pf02882"	"25902"	"ENSG00000120254"	"MTHFD1L"	"hsa:25902; Q2TBF3; Q6UB35; Q8WVW0; Q96HG8; Q9H789; Q9UFU8"	"One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways"	"Metabolism of folate and pterines"	"3"	"0"	"65.8"	"47.3"	"60.6"	"54.6"	"56.9"	"54.9"	"70.4"	"151.7"	"155.9"	"398.6"	"528.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5JXB2"	"Putative ubiquitin-conjugating enzyme E2 N-like OS=Homo sapiens OX=9606 GN=UBE2NL PE=1 SV=1"	"0.000"	""	"20"	"2"	"4"	"2"	"153"	"17.4"	"5.92"	"964.91"	"7.94"	"2"	"2"	"protein metabolism;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00179"	"389898"	""	"UBE2NL"	"E9KL27; hsa:389898; Q5JXB2"	""	""	"0"	"0"	"41.3"	"31.6"	"48.8"	"45.6"	"55.8"	"44.9"	"55.0"	"109.5"	"102.9"	"420.0"	"1146.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14373"	"Zinc finger protein RFP OS=Homo sapiens OX=9606 GN=TRIM27 PE=1 SV=1"	"0.000"	""	"3"	"1"	"4"	"1"	"513"	"58.5"	"6.21"	"938.78"	"7.94"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"other membranes;cytosol;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00622, Pf00643, Pf13765, Pf15227"	"5987"	"ENSG00000204713; ENSG00000215641; ENSG00000229006; ENSG00000234495; ENSG00000237071"	"TRIM27"	"A2BE15; hsa:5987; P14373; Q5RJA8; Q5ST26; Q6LA73; Q6NXR9; Q9BZY6; Q9UJL3"	""	"Regulation of PTEN stability and activity; SUMOylation of ubiquitinylation proteins; Suppression of apoptosis"	"3"	"0"	"98.9"	"58.5"	"80.0"	"71.7"	"79.6"	"79.3"	"108.1"	"138.5"	"137.0"	"263.7"	"349.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BY42"	"Replication termination factor 2 OS=Homo sapiens OX=9606 GN=RTF2 PE=1 SV=3"	"0.000"	""	"9"	"3"	"5"	"3"	"306"	"33.9"	"8.59"	"975.68"	"7.93"	"3"	"2"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf04641"	"51507"	"ENSG00000022277"	"RTF2"	"E1P5Z9; hsa:51507; Q9BY42; Q9BYL7; Q9HCV9; Q9NX29; Q9NZZ8; Q9P002; Q9UHW3"	""	""	"0"	"0"	"72.8"	"76.7"	"95.4"	"79.8"	"85.2"	"78.8"	"104.0"	"297.1"	"307.7"	"521.0"	"678.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P83881"	"60S ribosomal protein L36a OS=Homo sapiens OX=9606 GN=RPL36A PE=1 SV=2"	"0.000"	""	"29"	"4"	"6"	"4"	"106"	"12.4"	"10.58"	"838.92"	"7.92"	"3"	"3"	"protein metabolism;other metabolic processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;translational apparatus"	"other molecular function"	"Pf00935"	"6173"	"ENSG00000241343"	"RPL36A"	"hsa:6173; P09896; P10661; P83881; Q08ES5; Q5J9I6"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"771.2"	"729.2"	"674.5"	"629.8"	"686.9"	"672.2"	"929.0"	"1163.9"	"1104.5"	"2097.6"	"3255.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00151"	"PDZ and LIM domain protein 1 OS=Homo sapiens OX=9606 GN=PDLIM1 PE=1 SV=4"	"0.000"	""	"6"	"2"	"6"	"2"	"329"	"36.0"	"7.02"	"973.92"	"7.90"	"2"	"2"	"cell organization and biogenesis;stress response;developmental processes;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412, Pf00595, Pf15936"	"9124"	"ENSG00000107438"	"PDLIM1"	"B2RBS6; hsa:9124; O00151; Q5VZH5; Q9BPZ9"	""	""	"0"	"0"	"106.4"	"87.5"	"116.0"	"109.9"	"94.9"	"99.0"	"125.8"	"225.3"	"216.4"	"677.1"	"1138.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35606"	"Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"906"	"102.4"	"5.27"	"1030.63"	"7.89"	"2"	"2"	"transport"	"other membranes;cytosol;ER/Golgi"	"other molecular function"	"Pf00400, Pf04053"	"9276"	"ENSG00000184432"	"COPB2"	"B4DZI8; hsa:9276; P35606"	""	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport"	"2"	"0"	"84.9"	"66.4"	"66.1"	"68.2"	"57.1"	"78.0"	"88.9"	"147.0"	"146.0"	"341.5"	"645.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15560"	"Transcription elongation factor A protein 2 OS=Homo sapiens OX=9606 GN=TCEA2 PE=1 SV=1"	"0.000"	""	"12"	"3"	"6"	"1"	"299"	"33.6"	"9.13"	"1413.00"	"7.87"	"3"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01096, Pf07500, Pf08711"	"6919"	"ENSG00000171703"	"TCEA2"	"B3KNM1; hsa:6919; Q15560; Q8TD37; Q8TD38"	""	""	"0"	"0"	"65.6"	"46.4"	"63.7"	"65.5"	"62.7"	"57.4"	"90.8"	"136.4"	"131.9"	"216.7"	"294.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q1L5Z9"	"LON peptidase N-terminal domain and RING finger protein 2 OS=Homo sapiens OX=9606 GN=LONRF2 PE=2 SV=3"	"0.000"	""	"4"	"2"	"4"	"2"	"754"	"83.6"	"5.90"	"934.33"	"7.87"	"2"	"2"	""	"other cell component"	"other molecular function"	"Pf02190, Pf13923"	"164832"	"ENSG00000170500"	"LONRF2"	"B9A006; hsa:164832; Q1L5Z9; Q6ZSR4"	""	""	"0"	"0"	"3.4"	"6.1"	"7.1"	"6.6"	"8.0"	"8.7"	"7.8"	"36.2"	"37.5"	"147.4"	"273.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P2N5"	"RNA-binding protein 27 OS=Homo sapiens OX=9606 GN=RBM27 PE=1 SV=2"	"0.000"	""	"2"	"2"	"4"	"1"	"1060"	"118.6"	"9.19"	"821.74"	"7.87"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf00076, Pf00642, Pf01480"	"54439"	"ENSG00000091009"	"RBM27"	"hsa:54439; Q8IYW9; Q9P2N5"	""	""	"0"	"0"	"47.5"	"40.7"	"40.8"	"44.0"	"48.3"	"34.9"	"62.9"	"128.4"	"145.0"	"362.7"	"526.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q02543"	"60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2"	"0.000"	""	"14"	"3"	"6"	"3"	"176"	"20.7"	"10.71"	"800.79"	"7.86"	"3"	"3"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01775"	"6142"	"ENSG00000105640"	"RPL18A"	"hsa:6142; Q02543"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"15"	"0"	"433.4"	"415.4"	"423.8"	"440.9"	"435.9"	"410.0"	"540.5"	"817.0"	"774.9"	"1631.7"	"2921.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BYD6"	"39S ribosomal protein L1, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL1 PE=1 SV=2"	"0.000"	""	"13"	"4"	"7"	"4"	"325"	"36.9"	"8.78"	"1752.12"	"7.86"	"4"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00687"	"65008"	"ENSG00000169288"	"MRPL1"	"A6NG03; hsa:65008; Q4W5B8; Q6IAG4; Q96BW3; Q9BYD6; Q9H793; Q9NRL5"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"409.8"	"291.4"	"430.6"	"379.4"	"362.5"	"449.2"	"651.5"	"2616.5"	"2494.9"	"3651.3"	"4204.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19022"	"Cadherin-2 OS=Homo sapiens OX=9606 GN=CDH2 PE=1 SV=4"	"0.000"	""	"4"	"3"	"5"	"3"	"906"	"99.7"	"4.81"	"1076.16"	"7.85"	"3"	"2"	"cell adhesion;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00028, Pf01049, Pf08758"	"1000"	"ENSG00000170558"	"CDH2"	"A8MWK3; B0YIY6; hsa:1000; P19022; Q14923; Q8N173"	"Neural crest differentiation; Arrhythmogenic right ventricular cardiomyopathy; Brain-derived neurotrophic factor (BDNF) signaling pathway; Primary focal segmental glomerulosclerosis (FSGS); Splicing factor NOVA regulated synaptic proteins; Epithelial to mesenchymal transition in colorectal cancer; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; Pleural mesothelioma; CCL18 signaling pathway; GDNF signaling; A network map of Macrophage-stimulating protein (MSP) signaling"	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Myogenesis; Adherens junctions interactions"	"16"	"0"	"186.4"	"293.4"	"193.9"	"186.4"	"166.6"	"200.0"	"225.4"	"341.9"	"341.4"	"652.1"	"820.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P0K7"	"Ankycorbin OS=Homo sapiens OX=9606 GN=RAI14 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"980"	"110.0"	"6.21"	"929.12"	"7.83"	"2"	"2"	"other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf00023, Pf12796"	"26064"	"ENSG00000039560"	"RAI14"	"E9PED3; hsa:26064; Q6V1W9; Q7Z5I4; Q7Z733; Q9P0K7; Q9P2L2; Q9Y3T5"	""	""	"0"	"0"	"81.5"	"64.4"	"81.7"	"71.3"	"72.5"	"83.9"	"104.2"	"175.7"	"168.5"	"323.2"	"404.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15372"	"Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1"	"0.000"	""	"9"	"2"	"4"	"2"	"352"	"39.9"	"6.54"	"828.38"	"7.83"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01398, Pf19445"	"8667"	"ENSG00000147677"	"EIF3H"	"hsa:8667; O15372"	"Translation factors; VEGFA-VEGFR2 signaling; Measles virus infection; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"10"	"0"	"23.0"	"15.8"	"34.1"	"26.9"	"23.7"	"30.6"	"35.5"	"61.3"	"66.8"	"120.3"	"195.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86W92"	"Liprin-beta-1 OS=Homo sapiens OX=9606 GN=PPFIBP1 PE=1 SV=2"	"0.000"	""	"4"	"3"	"5"	"3"	"1011"	"114.0"	"5.55"	"527.54"	"7.83"	"2"	"3"	"cell adhesion;cell organization and biogenesis"	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf00536, Pf07647"	"8496"	"ENSG00000110841"	"PPFIBP1"	"hsa:8496; O75336; Q86W92; Q86X70; Q9NY03; Q9ULJ0"	""	"Signaling by ALK fusions and activated point mutants; Receptor-type tyrosine-protein phosphatases"	"2"	"0"	"53.9"	"52.3"	"66.0"	"56.8"	"52.5"	"51.1"	"70.8"	"96.3"	"73.8"	"116.7"	"165.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P60866"	"40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1"	"0.000"	""	"13"	"2"	"4"	"2"	"119"	"13.4"	"9.94"	"812.93"	"7.83"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00338"	"6224"	"ENSG00000008988"	"RPS20"	"B2R4F4; B4DW28; hsa:6224; P17075; P60866; Q5M8S9"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"96.7"	"86.5"	"113.3"	"101.2"	"100.9"	"111.2"	"124.8"	"168.2"	"182.7"	"311.7"	"386.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z4Q2"	"HEAT repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=HEATR3 PE=1 SV=2"	"0.000"	""	"2"	"1"	"6"	"1"	"680"	"74.5"	"5.11"	"972.44"	"7.82"	"1"	"1"	"transport;other biological processes"	""	"other molecular function"	"Pf13513"	"55027"	"ENSG00000155393"	"HEATR3"	"A8K1N4; hsa:55027; Q7Z4Q2; Q8N525; Q8WV56; Q96CC9; Q9NWN7"	""	""	"0"	"0"	"0.0"	"0.0"	"9.0"	"8.8"	"3.9"	"7.6"	"8.4"	"24.4"	"32.8"	"88.4"	"145.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P2T1"	"GMP reductase 2 OS=Homo sapiens OX=9606 GN=GMPR2 PE=1 SV=1"	"0.000"	""	"6"	"2"	"3"	"1"	"348"	"37.9"	"7.23"	"367.16"	"7.81"	"1"	"2"	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00478"	"51292"	"ENSG00000100938; ENSG00000284752"	"GMPR2"	"D3DS66; hsa:51292; Q567T0; Q6IAJ8; Q86T14; Q9P2T1"	""	"Purine salvage"	"1"	"1"	"31.5"	"25.4"	"30.6"	"30.1"	"29.6"	"36.2"	"69.8"	"379.9"	"388.7"	"1474.3"	"2624.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y285"	"Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3"	"0.000"	""	"2"	"2"	"4"	"2"	"508"	"57.5"	"7.80"	"868.90"	"7.76"	"2"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01409, Pf18552, Pf18553, Pf18554"	"2193"	"ENSG00000179115"	"FARSA"	"B4E363; hsa:2193; Q9NSD8; Q9Y285; Q9Y4W8"	""	"Cytosolic tRNA aminoacylation"	"1"	"0"	"151.4"	"128.4"	"180.1"	"149.9"	"162.6"	"170.1"	"198.4"	"277.8"	"259.3"	"446.3"	"554.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61011"	"Signal recognition particle 54 kDa protein OS=Homo sapiens OX=9606 GN=SRP54 PE=1 SV=1"	"0.000"	""	"6"	"2"	"4"	"2"	"504"	"55.7"	"8.75"	"739.76"	"7.76"	"2"	"2"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00448, Pf02881, Pf02978"	"6729"	"ENSG00000100883"	"SRP54"	"B2R759; B4DUW6; hsa:6729; P13624; P61011"	"VEGFA-VEGFR2 signaling; mRNA processing"	"SRP-dependent cotranslational protein targeting to membrane"	"3"	"0"	"27.4"	"22.2"	"34.3"	"30.4"	"31.3"	"29.7"	"40.1"	"77.3"	"80.3"	"159.2"	"230.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60701"	"UDP-glucose 6-dehydrogenase OS=Homo sapiens OX=9606 GN=UGDH PE=1 SV=1"	"0.000"	""	"5"	"2"	"5"	"2"	"494"	"55.0"	"7.12"	"920.10"	"7.75"	"2"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes"	"cytosol;nucleus"	"other molecular function"	"Pf00984, Pf03720, Pf03721"	"7358"	"ENSG00000109814"	"UGDH"	"B3KUU2; B4DN25; hsa:7358; O60589; O60701"	"UDP-derived sugars synthesis in fibroblasts; Glucuronidation"	"Formation of the active cofactor, UDP-glucuronate"	"3"	"0"	"79.0"	"54.3"	"100.0"	"93.1"	"84.3"	"90.4"	"121.9"	"219.4"	"230.0"	"465.3"	"584.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3D7"	"Mitochondrial import inner membrane translocase subunit TIM16 OS=Homo sapiens OX=9606 GN=PAM16 PE=1 SV=2"	"0.000"	""	"27"	"2"	"3"	"2"	"125"	"13.8"	"9.70"	"252.24"	"7.74"	"1"	"2"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion;other cell component"	""	"Pf03656"	"51025"	"ENSG00000217930; ENSG00000282228"	"PAM16"	"hsa:51025; Q6I9Z3; Q9H5X3; Q9Y3D7"	""	"Mitochondrial protein import"	"1"	"0"	"51.0"	"42.1"	"47.9"	"47.9"	"40.0"	"34.2"	"54.1"	"95.5"	"101.3"	"208.2"	"275.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75794"	"Cell division cycle protein 123 homolog OS=Homo sapiens OX=9606 GN=CDC123 PE=1 SV=1"	"0.000"	""	"5"	"2"	"6"	"2"	"336"	"39.1"	"4.81"	"926.93"	"7.73"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"other cell component"	""	"Pf07065"	"8872"	"ENSG00000151465"	"CDC123"	"A8JZZ7; hsa:8872; O75794; Q14107; Q5T0L4; Q5T0L5; Q5T0L7; Q5T0L8; Q5T0L9"	""	""	"0"	"0"	"82.8"	"70.1"	"107.5"	"92.2"	"79.0"	"61.3"	"95.0"	"2090.6"	"2125.1"	"3262.3"	"2235.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P82650"	"28S ribosomal protein S22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS22 PE=1 SV=1"	"0.000"	""	"9"	"3"	"7"	"3"	"360"	"41.3"	"7.90"	"1279.24"	"7.70"	"3"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf10245"	"56945"	"ENSG00000175110"	"MRPS22"	"hsa:56945; P82650; Q9H3I1"	"Primary ovarian insufficiency"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"4"	"0"	"206.9"	"167.4"	"212.3"	"183.9"	"218.0"	"183.5"	"257.8"	"358.8"	"359.9"	"706.1"	"952.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P16220"	"Cyclic AMP-responsive element-binding protein 1 OS=Homo sapiens OX=9606 GN=CREB1 PE=1 SV=2"	"0.000"	""	"8"	"2"	"3"	"2"	"341"	"36.7"	"5.57"	"664.00"	"7.69"	"1"	"2"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00170, Pf02173"	"100351999; 100477711; 100586647; 100675162; 100974672; 101010524; 101356881; 101383024; 101608568; 101964691; 102141699; 102246867; 102428529; 102531048; 102748542; 103217717; 103744440; 104680220; 105468005; 105517357; 105549382; 105580103; 105864304; 106967098; 108540349; 109691946; 1385; 459901; 607922; 708717"	"ENSAMEG00000015152; ENSCAFG00000013510; ENSCAFG00030010510; ENSCAFG00040025786; ENSCAFG00845022020; ENSCANG00000030079; ENSCATG00000037133; ENSCCNG00000003127; ENSCSAG00000010111; ENSFCAG00000008220; ENSGGOG00000024394; ENSJJAG00000013846; ENSLAFG00000013257; ENSLCNG00005016477; ENSMFAG00000039629; ENSMICG00000009731; ENSMLEG00000033904; ENSMLUG00000016119; ENSMMMG00000014914; ENSMMUG00000022601; ENSMNEG00000030274; ENSNGAG00000018967; ENSNLEG00000007124; ENSOCUG00000005427; ENSPANG00000009083; ENSPLOG00000007090; ENSPPAG00000042817; ENSPPYG00000013115; ENSPTIG00000011848; ENSPTRG00000043959; ENSRBIG00000040701; ENSRFEG00010020193; ENSRROG00000035316; ENSSDAG00000020160; ENSSSCG00005034714; ENSSSCG00015008370; ENSSSCG00025020324; ENSSSCG00030035186; ENSSSCG00035079382; ENSSSCG00040036512; ENSSSCG00045023175; ENSSSCG00050037141; ENSSSCG00055008554; ENSSSCG00060058264; ENSSSCG00065052126; ENSSSCG00070020566; ENSSSUG00005001816; ENSSTOG00000016482; ENSSVLG00005003093; ENSTGEG00000004249; ENSUAMG00000018783; ENSUMAG00000022656; ENSUPAG00010007984; ENSVVUG00000011892"	"Creb1; CREB1; LOC101356881"	"A0A024R401; A0A096MS95; A0A0D9RCK8; A0A286ZWB0; A0A2I2YCF6; A0A2J8N5U5; A0A2J8WUF2; A0A2K5I9K2; A0A2K5MQP0; A0A2K5X536; A0A2K5X539; A0A2K5YUX5; A0A2K6BKD0; A0A2K6MDT5; A0A2K6Q2B5; A0A2R9CPF8; A0A2U3WAS2; A0A2U3XPQ5; A0A2Y9R2V7; A0A384BST9; A0A3Q7QRU5; A0A3Q7SQX8; A0A452RWS8; A0A4X1V0B9; A0A5E4AFY5; A0A5N4E668; A0A667HEB5; A0A671G6M8; A0A673T0V2; A0A6D2VSK7; A0A6D2WEQ2; A0A6G1BFF3; A0A6I9IA29; A0A6J1YUG6; A0A6J2CMJ0; A0A6J2LK21; A0A6P6GX89; A0A7J7WGC8; A0A7J7XTS6; A0A7J8FQY6; A0A811ZBK8; A0A8B7V7Z4; A0A8B8T0S6; A0A8C0N7M6; A0A8C5KHE0; A0A8C5V357; A0A8C6EUY0; A0A8C6RKM3; A0A8C8WVH7; A0A8C9JRV6; A0A8C9Q947; A0A8D2AN63; A0A8D2EE05; A0A8D2H908; A0A8I3S2U7; A0A8J8XE04; A0A8J8XJ71; A0A8M1M6Z7; aju:106967098; aml:100477711; cang:105517357; caty:105580103; ccan:109691946; cfa:607922; cfr:102508765; csab:103217717; D2H8G8; F7AUB4; G1PTV7; G1R662; G1SNW9; G3TAZ1; G7N8R8; H2P8F2; H2R2Y2; I3MRM5; lav:100675162; lww:102748542; M3W964; mcc:708717; mcf:102141699; mleu:105549382; mlf:102428529; mmur:105864304; myb:102246867; ngi:103744440; ocu:100351999; oro:101383024; pdic:114495167; ptr:459901; Q5U0J5; rbb:108540349; rro:104680220; S7N6N9; tmu:101356881; umr:103659802; vpc:102531048; vvp:112922611; zca:113919503"	"IL-2 signaling pathway; EGFR1 signaling pathway; Adipogenesis; Androgen receptor signaling pathway; p38 MAPK signaling pathway; G1 to S cell cycle control; Androgen receptor signaling pathway; miRNA regulation of DNA damage response; Energy metabolism; miRNAs involved in DNA damage response; Folate-alcohol and cancer pathway hypotheses; Thyroid stimulating hormone (TSH) signaling pathway; Leptin signaling pathway; Follicle stimulating hormone (FSH) signaling pathway; B cell receptor signaling pathway; Interleukin-11 signaling pathway; Corticotropin-releasing hormone signaling pathway; Adipogenesis; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; ATM signaling pathway; Myometrial relaxation and contraction pathways; VEGFA-VEGFR2 signaling; Mitochondrial gene expression; p38 MAPK signaling pathway; EGF/EGFR signaling pathway; G1 to S cell cycle control; Gastrin signaling pathway; CAMKK2 pathway; Galanin receptor pathway; Neuroinflammation and glutamatergic signaling; GDNF signaling; Interferon type I signaling pathways; T-cell receptor signaling pathway; Sudden infant death syndrome (SIDS) susceptibility pathways; DNA damage response; Estrogen signaling pathway; Serotonin HTR1 group and FOS pathway; Serotonin receptor 4/6/7 and NR3C signaling; EGFR1 signaling pathway; Adipogenesis; Androgen receptor signaling pathway; p38 MAPK signaling pathway; G1 to S cell cycle control"	"NCAM signaling for neurite out-growth; CREB phosphorylation; CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling; Gastrin-CREB signalling pathway via PKC and MAPK; NGF-stimulated transcription"	"49"	"0"	"89.6"	"58.8"	"103.3"	"91.4"	"80.4"	"78.6"	"110.5"	"194.8"	"205.6"	"530.9"	"715.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15853"	"Upstream stimulatory factor 2 OS=Homo sapiens OX=9606 GN=USF2 PE=1 SV=1"	"0.000"	""	"7"	"3"	"6"	"1"	"346"	"36.9"	"5.10"	"803.29"	"7.69"	"3"	"3"	"transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00010"	"7392"	"ENSG00000105698"	"USF2"	"hsa:7392; O00671; O00709; Q05750; Q07952; Q15851; Q15852; Q15853; Q6FI33; Q6YI47"	"Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4)"	"Estrogen-dependent gene expression"	"2"	"1"	"331.6"	"234.8"	"307.8"	"320.7"	"296.1"	"237.2"	"379.3"	"577.7"	"595.0"	"1102.7"	"1380.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60551"	"Glycylpeptide N-tetradecanoyltransferase 2 OS=Homo sapiens OX=9606 GN=NMT2 PE=1 SV=1"	"0.000"	""	"8"	"3"	"5"	"1"	"498"	"56.9"	"7.58"	"1267.70"	"7.68"	"3"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf01233, Pf02799"	"9397"	"ENSG00000152465"	"NMT2"	"B0YJ49; hsa:9397; O60551; Q53Y38; Q5VUC8; Q9BRB4"	""	"Membrane binding and targetting of GAG proteins; Inactivation, recovery and regulation of the phototransduction cascade"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P53985"	"Monocarboxylate transporter 1 OS=Homo sapiens OX=9606 GN=SLC16A1 PE=1 SV=3"	"0.000"	""	"6"	"2"	"4"	"2"	"500"	"53.9"	"8.66"	"821.92"	"7.66"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"transporter activity;other molecular function"	"Pf07690"	"6566"	"ENSG00000155380; ENSG00000281917"	"SLC16A1"	"hsa:6566; P53985; Q49A45; Q5T8R6; Q9NSJ9"	"Photodynamic therapy-induced HIF-1 survival signaling; Fragile X syndrome; Glucose metabolism in triple-negative breast cancer cells"	"Pyruvate metabolism; Aspirin ADME; Basigin interactions; Proton-coupled monocarboxylate transport; Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT)"	"8"	"0"	"55.5"	"50.7"	"47.8"	"50.8"	"52.0"	"44.5"	"64.6"	"107.2"	"100.3"	"198.2"	"262.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49821"	"NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV1 PE=1 SV=4"	"0.000"	""	"6"	"2"	"4"	"2"	"464"	"50.8"	"8.21"	"834.71"	"7.66"	"2"	"2"	"other metabolic processes;transport"	"other membranes;cytosol;mitochondrion"	"transporter activity;other molecular function"	"Pf01512, Pf10531, Pf10589"	"4723"	"ENSG00000167792"	"NDUFV1"	"hsa:4723; O60924; O60940; P49821; Q16104; Q6IBR3; Q96BF8; Q96HS7"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"73.6"	"51.8"	"74.3"	"84.6"	"84.5"	"72.6"	"90.0"	"205.1"	"209.8"	"517.6"	"693.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50579"	"Methionine aminopeptidase 2 OS=Homo sapiens OX=9606 GN=METAP2 PE=1 SV=1"	"0.000"	""	"9"	"2"	"3"	"2"	"478"	"52.9"	"5.82"	"299.21"	"7.66"	"1"	"2"	"protein metabolism;other metabolic processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00557"	"10988"	"ENSG00000111142"	"METAP2"	"B2RDI8; B4DUX5; G3XA91; hsa:10988; P50579; Q8NB11"	""	"Inactivation, recovery and regulation of the phototransduction cascade"	"1"	"0"	"0.0"	"0.0"	"2.2"	"2.6"	"0.0"	"3.4"	"3.7"	"24.2"	"23.1"	"50.3"	"44.2"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12789"	"General transcription factor 3C polypeptide 1 OS=Homo sapiens OX=9606 GN=GTF3C1 PE=1 SV=4"	"0.000"	""	"2"	"3"	"5"	"3"	"2109"	"238.7"	"7.30"	"1310.36"	"7.64"	"3"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04182"	"2975"	"ENSG00000077235"	"GTF3C1"	"B2RP21; hsa:2975; Q12789; Q12838; Q6DKN9; Q9Y4W9"	""	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter"	"3"	"0"	"52.0"	"30.4"	"61.3"	"46.8"	"41.7"	"48.9"	"67.9"	"120.6"	"122.2"	"420.5"	"600.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16718"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 OS=Homo sapiens OX=9606 GN=NDUFA5 PE=1 SV=3"	"0.000"	""	"24"	"2"	"4"	"2"	"116"	"13.5"	"5.99"	"682.10"	"7.63"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf04716"	"4698"	"ENSG00000128609"	"NDUFA5"	"B2RD98; hsa:4698; Q16718; Q5H9R2; Q6IRX7"	"Electron transport chain: OXPHOS system in mitochondria; Ciliary landscape; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis; RHOG GTPase cycle"	"7"	"0"	"53.4"	"35.2"	"51.4"	"36.6"	"44.8"	"52.7"	"68.2"	"148.1"	"155.1"	"361.0"	"412.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14923"	"Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3"	"0.000"	""	"5"	"3"	"5"	"2"	"745"	"81.7"	"6.14"	"1006.94"	"7.63"	"3"	"2"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00514"	"3728"	"ENSG00000173801"	"JUP"	"hsa:3728; P14923; Q15093; Q15151; Q7L3S5; Q86W21; Q9BWC4; Q9HCX9"	"Arrhythmogenic right ventricular cardiomyopathy; Corticotropin-releasing hormone signaling pathway; Ectoderm differentiation; Ectoderm differentiation; Epithelial to mesenchymal transition in colorectal cancer; Opioid receptor pathways"	"Neutrophil degranulation; RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RHOB GTPase cycle; Formation of the cornified envelope; RHOQ GTPase cycle; RHOJ GTPase cycle; VEGFR2 mediated vascular permeability; Adherens junctions interactions; Regulation of CDH11 function; Regulation of CDH19 Expression and Function; CDH11 homotypic and heterotypic interactions; RHOH GTPase cycle"	"21"	"0"	"137.9"	"114.7"	"210.3"	"138.8"	"166.5"	"107.9"	"161.8"	"287.5"	"321.5"	"584.8"	"820.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y678"	"Coatomer subunit gamma-1 OS=Homo sapiens OX=9606 GN=COPG1 PE=1 SV=1"	"0.000"	""	"3"	"2"	"4"	"2"	"874"	"97.7"	"5.47"	"946.16"	"7.62"	"2"	"2"	"transport;other biological processes"	"other membranes;cytosol;ER/Golgi"	"other molecular function"	"Pf01602, Pf08752, Pf16381"	"22820"	"ENSG00000181789"	"COPG1"	"A8K6M8; B3KMF6; hsa:22820; Q54AC4; Q9Y678"	"VEGFA-VEGFR2 signaling"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport"	"3"	"0"	"159.6"	"118.2"	"118.5"	"133.5"	"113.6"	"123.0"	"141.0"	"209.7"	"194.0"	"383.8"	"540.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94763"	"Unconventional prefoldin RPB5 interactor 1 OS=Homo sapiens OX=9606 GN=URI1 PE=1 SV=3"	"0.000"	""	"7"	"3"	"6"	"2"	"535"	"59.8"	"5.05"	"871.97"	"7.60"	"3"	"3"	"other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02996"	"8725"	"ENSG00000105176"	"URI1"	"A8K805; H7BY42; hsa:8725; O94763; Q8TC23; Q9UNU3"	""	""	"0"	"0"	"4.4"	"3.1"	"4.8"	"5.3"	"3.8"	"4.2"	"6.3"	"21.3"	"19.8"	"60.3"	"87.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11233"	"Ras-related protein Ral-A OS=Homo sapiens OX=9606 GN=RALA PE=1 SV=1"	"0.000"	""	"14"	"3"	"5"	"3"	"206"	"23.6"	"7.11"	"1009.05"	"7.60"	"3"	"2"	"cell cycle OR cell proliferation;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;mitochondrion;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00071"	"5898"	"ENSG00000006451"	"RALA"	"A4D1W3; hsa:5898; P11233"	"RalA downstream regulated genes; Chromosomal and microsatellite instability in colorectal cancer ; Ras signaling; Pancreatic adenocarcinoma pathway; EGF/EGFR signaling pathway"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; p38MAPK events"	"8"	"0"	"196.6"	"156.5"	"204.3"	"191.3"	"175.0"	"188.2"	"252.0"	"659.9"	"653.4"	"1416.1"	"1548.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15436"	"Protein transport protein Sec23A OS=Homo sapiens OX=9606 GN=SEC23A PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"1"	"765"	"86.1"	"7.08"	"755.14"	"7.59"	"2"	"2"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00626, Pf04810, Pf04811, Pf04815, Pf08033"	"10484"	"ENSG00000100934"	"SEC23A"	"B2R5P4; B3KXI2; hsa:10484; Q15436; Q8NE16"	"Sterol regulatory element-binding proteins (SREBP) signaling"	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC; COPII-mediated vesicle transport; MHC class II antigen presentation; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Cargo concentration in the ER; Regulation of cholesterol biosynthesis by SREBP (SREBF)"	"7"	"0"	"59.5"	"50.0"	"64.2"	"48.2"	"61.6"	"51.7"	"75.8"	"105.3"	"105.4"	"232.7"	"372.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5B6"	"PAX3- and PAX7-binding protein 1 OS=Homo sapiens OX=9606 GN=PAXBP1 PE=1 SV=2"	"0.000"	""	"5"	"3"	"5"	"3"	"917"	"104.7"	"5.68"	"973.32"	"7.58"	"3"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf07842"	"94104"	"ENSG00000159086; ENSG00000263141"	"PAXBP1"	"D3DSE7; hsa:94104; Q96DU8; Q9NYQ0; Q9Y5B6"	""	""	"0"	"0"	"153.9"	"149.0"	"159.1"	"149.6"	"152.0"	"141.0"	"180.0"	"217.0"	"213.9"	"508.9"	"866.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2A7"	"Nck-associated protein 1 OS=Homo sapiens OX=9606 GN=NCKAP1 PE=1 SV=1"	"0.000"	""	"4"	"4"	"5"	"4"	"1128"	"128.7"	"6.62"	"1077.66"	"7.58"	"3"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	""	"Pf09735"	"10787"	"ENSG00000061676"	"NCKAP1"	"hsa:10787; O60329; Q53QN5; Q53S94; Q53Y35; Q9Y2A7"	"Exercise-induced circadian regulation; Regulation of actin cytoskeleton"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; VEGFA-VEGFR2 Pathway"	"9"	"0"	"175.9"	"134.6"	"171.2"	"179.5"	"176.1"	"158.4"	"235.1"	"505.7"	"503.3"	"962.2"	"1152.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVH1"	"DnaJ homolog subfamily C member 11 OS=Homo sapiens OX=9606 GN=DNAJC11 PE=1 SV=2"	"0.000"	""	"5"	"2"	"3"	"2"	"559"	"63.2"	"8.40"	"695.81"	"7.58"	"1"	"2"	"cell organization and biogenesis"	"other membranes;mitochondrion;nucleus"	""	"Pf00226, Pf11875"	"55735"	"ENSG00000007923"	"DNAJC11"	"hsa:55735; Q4VWF5; Q5VZN0; Q6PK20; Q6PK70; Q8NDM2; Q96CL7; Q9NVH1"	""	"Cristae formation"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96HS1"	"Serine/threonine-protein phosphatase PGAM5, mitochondrial OS=Homo sapiens OX=9606 GN=PGAM5 PE=1 SV=2"	"0.000"	""	"8"	"2"	"5"	"2"	"289"	"32.0"	"8.68"	"1222.66"	"7.55"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion"	"enzyme regulator activity;other molecular function"	"Pf00300"	"192111"	"ENSG00000247077"	"PGAM5"	"A9LN06; C9IZY7; hsa:192111; Q96HS1; Q96JB0"	"NRF2-ARE regulation"	""	"1"	"0"	"93.1"	"71.3"	"107.8"	"95.8"	"94.1"	"104.7"	"113.8"	"191.3"	"214.2"	"501.7"	"773.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08237"	"ATP-dependent 6-phosphofructokinase, muscle type OS=Homo sapiens OX=9606 GN=PFKM PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"780"	"85.1"	"7.99"	"731.07"	"7.51"	"2"	"2"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus"	"kinase activity;other molecular function"	"Pf00365"	"5213"	"ENSG00000152556"	"PFKM"	"hsa:5213; J3KNX3; P08237; Q16814; Q16815; Q6ZTT1"	"Clear cell renal cell carcinoma pathways; Aerobic glycolysis; Insulin signaling; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"Glycolysis"	"6"	"0"	"127.0"	"102.2"	"121.1"	"115.4"	"119.3"	"108.3"	"149.5"	"262.3"	"254.1"	"490.5"	"631.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P36959"	"GMP reductase 1 OS=Homo sapiens OX=9606 GN=GMPR PE=1 SV=1"	""	""	"9"	"2"	"2"	"1"	"345"	"37.4"	"7.06"	""	"7.50"	""	"2"	"other metabolic processes;stress response"	"cytosol;other cell component"	"other molecular function"	"Pf00478"	"2766"	"ENSG00000137198"	"GMPR"	"hsa:2766; P36959; Q96HQ6"	""	"Purine salvage"	"1"	"0"	"5.9"	"3.0"	"7.6"	"5.7"	"5.6"	"9.3"	"6.8"	"30.9"	"38.5"	"102.2"	"190.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5RKV6"	"Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1"	"0.000"	""	"12"	"2"	"3"	"2"	"272"	"28.2"	"6.28"	"248.83"	"7.50"	"1"	"2"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	""	"Pf01138"	"118460"	"ENSG00000223496"	"EXOSC6"	"hsa:118460; Q5RKV6"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	"6"	"0"	"22.9"	"15.8"	"30.2"	"35.5"	"26.7"	"24.8"	"31.2"	"47.0"	"48.7"	"114.3"	"201.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q86X55"	"Histone-arginine methyltransferase CARM1 OS=Homo sapiens OX=9606 GN=CARM1 PE=1 SV=3"	""	""	"4"	"1"	"1"	"1"	"608"	"65.8"	"6.73"	""	"7.50"	""	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06325, Pf11531"	"10498"	"ENSG00000142453"	"CARM1"	"A6NN38; hsa:10498; Q86X55"	"Androgen receptor signaling pathway; Nitric oxide metabolism in cystic fibrosis"	"Estrogen-dependent gene expression; RMTs methylate histone arginines; PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; Heme signaling; BMAL1:CLOCK,NPAS2 activates circadian gene expression; Transcriptional activation of mitochondrial biogenesis; Cytoprotection by HMOX1; Activation of gene expression by SREBF (SREBP); TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; RORA activates gene expression"	"15"	"0"	"15.2"	"12.5"	"17.2"	"15.7"	"17.8"	"18.1"	"17.2"	"38.8"	"37.6"	"95.6"	"125.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12899"	"Tripartite motif-containing protein 26 OS=Homo sapiens OX=9606 GN=TRIM26 PE=1 SV=1"	"0.000"	""	"5"	"2"	"4"	"2"	"539"	"62.1"	"5.03"	"1071.91"	"7.50"	"2"	"2"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00622, Pf00643, Pf13765, Pf15227"	"7726"	"ENSG00000137313; ENSG00000226060; ENSG00000228881; ENSG00000230230; ENSG00000231002; ENSG00000231641; ENSG00000234046; ENSG00000234127"	"TRIM26"	"A6NG96; hsa:7726; Q12899; Q5SRL2"	""	"Interferon gamma signaling"	"1"	"0"	"30.5"	"22.8"	"24.7"	"24.3"	"27.5"	"22.2"	"29.8"	"42.2"	"45.0"	"83.3"	"128.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60245"	"Protocadherin-7 OS=Homo sapiens OX=9606 GN=PCDH7 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"1069"	"116.0"	"5.19"	"805.16"	"7.49"	"2"	"2"	"cell adhesion"	"plasma membrane;other membranes"	"other molecular function"	"Pf00028, Pf08266, Pf08374"	"5099"	"ENSG00000169851"	"PCDH7"	"hsa:5099; O60245; O60246; O60247; Q4W5C4"	""	"RHOA GTPase cycle; RHOB GTPase cycle; Platelet degranulation"	"3"	"0"	"36.6"	"27.0"	"33.4"	"34.5"	"32.4"	"38.9"	"50.5"	"157.1"	"186.7"	"582.7"	"932.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35250"	"Replication factor C subunit 2 OS=Homo sapiens OX=9606 GN=RFC2 PE=1 SV=3"	"0.000"	""	"9"	"2"	"4"	"2"	"354"	"39.1"	"6.44"	"802.60"	"7.49"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00004, Pf08542"	"5982"	"ENSG00000049541"	"RFC2"	"B5BU07; D3DXG3; hsa:5982; P32846; P35250; Q9BU93"	"DNA replication; Nucleotide excision repair; 7q11.23 copy number variation syndrome; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; HDR through Homologous Recombination (HRR); HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Dual incision in TC-NER; Dual Incision in GG-NER; Activation of ATR in response to replication stress; Termination of translesion DNA synthesis; Gap-filling DNA repair synthesis and ligation in TC-NER; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Polymerase switching on the C-strand of the telomere; Polymerase switching; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER"	"27"	"0"	"42.7"	"36.7"	"51.5"	"49.6"	"54.3"	"49.4"	"75.8"	"129.7"	"125.2"	"251.4"	"304.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75717"	"WD repeat and HMG-box DNA-binding protein 1 OS=Homo sapiens OX=9606 GN=WDHD1 PE=1 SV=1"	"0.000"	""	"2"	"2"	"4"	"2"	"1129"	"125.9"	"5.62"	"930.02"	"7.48"	"2"	"2"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400, Pf12341, Pf12894"	"11169"	"ENSG00000198554"	"WDHD1"	"C9JW18; F6W0U7; hsa:11169; O75717"	"Mesodermal commitment pathway"	""	"1"	"0"	"124.2"	"107.6"	"132.5"	"109.3"	"114.0"	"110.8"	"151.8"	"305.6"	"290.1"	"711.6"	"947.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09493"	"Tropomyosin alpha-1 chain OS=Homo sapiens OX=9606 GN=TPM1 PE=1 SV=2"	"0.000"	""	"15"	"4"	"6"	"4"	"284"	"32.7"	"4.74"	"1600.25"	"7.48"	"4"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00261"	"7168"	"ENSG00000140416"	"TPM1"	"B7Z5T7; D9YZV2; D9YZV3; D9YZV8; hsa:7168; P09493; P09494; P10469; Q6DV89; Q6DV90; Q7Z6L8; Q86W64; Q96IK2; Q9UCI1; Q9UCI2; Q9UCY9; Q9Y427"	"Vitamin D receptor pathway; Striated muscle contraction pathway"	"Smooth Muscle Contraction; Striated Muscle Contraction"	"4"	"0"	"211.6"	"147.3"	"220.2"	"204.4"	"183.4"	"170.7"	"201.3"	"463.5"	"437.2"	"1468.9"	"2053.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09496"	"Clathrin light chain A OS=Homo sapiens OX=9606 GN=CLTA PE=1 SV=1"	"0.000"	""	"15"	"5"	"8"	"5"	"248"	"27.1"	"4.51"	"1478.56"	"7.46"	"5"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01086"	"1211"	"ENSG00000122705"	"CLTA"	"A8K4W3; B4DIN1; F5H6N3; hsa:1211; P09496; Q2XPN5; Q53XZ1"	"Synaptic vesicle pathway; Ebola virus infection in host; Fragile X syndrome"	"Cargo recognition for clathrin-mediated endocytosis; LDL clearance; Recycling pathway of L1; MHC class II antigen presentation; Lysosome Vesicle Biogenesis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; Retrograde neurotrophin signalling; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; VLDLR internalisation and degradation; Entry of Influenza Virion into Host Cell via Endocytosis; Formation of annular gap junctions"	"17"	"0"	"1254.2"	"1058.6"	"1107.3"	"1043.8"	"987.2"	"941.9"	"1263.7"	"1413.0"	"1341.1"	"1874.6"	"2382.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q52LJ0"	"Protein FAM98B OS=Homo sapiens OX=9606 GN=FAM98B PE=1 SV=2"	"0.000"	""	"5"	"2"	"4"	"2"	"433"	"45.5"	"8.69"	"709.79"	"7.43"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf10239"	"283742"	"ENSG00000171262"	"FAM98B"	"A8MUW5; hsa:283742; Q52LJ0; Q8N935"	""	"tRNA processing in the nucleus"	"1"	"0"	"37.5"	"30.9"	"38.0"	"23.4"	"34.1"	"32.7"	"37.0"	"55.9"	"53.0"	"126.4"	"214.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94979"	"Protein transport protein Sec31A OS=Homo sapiens OX=9606 GN=SEC31A PE=1 SV=3"	"0.000"	""	"3"	"4"	"7"	"4"	"1220"	"132.9"	"6.89"	"1292.62"	"7.43"	"4"	"3"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf12931"	"22872"	"ENSG00000138674"	"SEC31A"	"B4DIW6; B7ZKZ7; B7ZL00; H7C2W3; hsa:22872; O94979; Q17RR5; Q5H9P6; Q5XG74; Q659G7; Q6ZU90; Q7LCX9; Q86TJ0; Q8IZH4; Q9P048; Q9P0A6; Q9UM05; Q9UM06"	"Sterol regulatory element-binding proteins (SREBP) signaling"	"MHC class II antigen presentation; Signaling by ALK fusions and activated point mutants; COPII-mediated vesicle transport; XBP1(S) activates chaperone genes; Antigen Presentation: Folding, assembly and peptide loading of class I MHC"	"6"	"0"	"242.0"	"208.2"	"234.1"	"250.3"	"242.5"	"218.4"	"250.3"	"657.3"	"669.5"	"1874.0"	"2851.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19404"	"NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV2 PE=1 SV=2"	"0.000"	""	"12"	"3"	"4"	"3"	"249"	"27.4"	"8.06"	"557.29"	"7.43"	"2"	"2"	"other metabolic processes;transport;developmental processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf01257"	"4729"	"ENSG00000178127"	"NDUFV2"	"hsa:4729; P19404; Q9BV41"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"129.7"	"113.3"	"140.9"	"110.5"	"138.5"	"124.7"	"140.3"	"350.1"	"319.1"	"693.1"	"798.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96B36"	"Proline-rich AKT1 substrate 1 OS=Homo sapiens OX=9606 GN=AKT1S1 PE=1 SV=1"	"0.000"	""	"5"	"1"	"4"	"1"	"256"	"27.4"	"4.75"	"671.92"	"7.43"	"1"	"1"	"cell organization and biogenesis;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf15798"	"84335"	"ENSG00000204673"	"AKT1S1"	"A8MTQ1; B2RE93; hsa:84335; J3KPM3; Q96B36; Q96BI4; Q96IK7; Q96NG2; Q9BWR5"	"Target of rapamycin signaling; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; VEGFA-VEGFR2 signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Clear cell renal cell carcinoma pathways; Thermogenesis; Fragile X syndrome; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Thyroid hormones production and peripheral downstream signaling effects; Autophagy; Perturbations to host-cell autophagy, induced by SARS-CoV-2 proteins; p53 transcriptional gene network; Pleural mesothelioma; Network map of SARS-CoV-2 signaling pathway; DYRK1A involvement regarding cell proliferation in brain development; JAK-STAT signaling in the regulation of Beta-cells"	"HSF1-dependent transactivation; Constitutive Signaling by AKT1 E17K in Cancer; mTORC1-mediated signalling; AKT phosphorylates targets in the cytosol"	"21"	"0"	"102.9"	"84.7"	"104.6"	"101.7"	"95.8"	"92.3"	"113.5"	"139.1"	"135.2"	"208.8"	"235.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P15531"	"Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1"	"0.000"	""	"24"	"2"	"3"	"1"	"152"	"17.1"	"6.19"	"375.25"	"7.43"	"1"	"2"	"DNA metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"translation activity;kinase activity;other molecular function"	"Pf00334"	"4830"	"ENSG00000239672"	"NME1"	"hsa:4830; P15531; Q6FGK3; Q86XQ2; Q9UDJ6"	"Pyrimidine metabolism"	"Interconversion of nucleotide di- and triphosphates; Azathioprine ADME; Ribavirin ADME"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09497"	"Clathrin light chain B OS=Homo sapiens OX=9606 GN=CLTB PE=1 SV=1"	"0.000"	""	"8"	"2"	"4"	"2"	"229"	"25.2"	"4.64"	"725.12"	"7.42"	"2"	"2"	"transport"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf01086"	"1212"	"ENSG00000175416"	"CLTB"	"hsa:1212; P09497; Q53Y37; Q6FHW1"	"Ebola virus infection in host; Fragile X syndrome; 5q35 copy number variation"	"Lysosome Vesicle Biogenesis; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; Formation of annular gap junctions"	"11"	"0"	"316.1"	"298.9"	"329.6"	"291.0"	"328.3"	"321.6"	"364.1"	"409.5"	"386.5"	"601.6"	"700.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96MX6"	"WD repeat-containing protein 92 OS=Homo sapiens OX=9606 GN=WDR92 PE=1 SV=1"	"0.000"	""	"7"	"2"	"4"	"2"	"357"	"39.7"	"8.09"	"797.00"	"7.42"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"other cell component"	"other molecular function"	"Pf00400"	"116143"	"ENSG00000243667"	"DNAAF10"	"hsa:116143; Q96CR6; Q96MX6"	""	""	"0"	"0"	"87.1"	"64.7"	"85.8"	"78.7"	"71.5"	"84.9"	"110.5"	"362.6"	"353.1"	"1108.9"	"1497.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IY57"	"YY1-associated factor 2 OS=Homo sapiens OX=9606 GN=YAF2 PE=1 SV=3"	"0.000"	""	"15"	"2"	"3"	"1"	"180"	"19.9"	"9.72"	"314.10"	"7.39"	"1"	"2"	"other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00641, Pf17219"	"10138"	"ENSG00000015153"	"YAF2"	"A8K5P0; B4DFU3; G3V465; hsa:10138; Q8IY57; Q99710"	""	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Transcriptional Regulation by E2F6"	"2"	"0"	"23.0"	"19.2"	"22.8"	"21.0"	"19.3"	"21.4"	"23.2"	"42.8"	"36.6"	"73.8"	"92.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P18848"	"Cyclic AMP-dependent transcription factor ATF-4 OS=Homo sapiens OX=9606 GN=ATF4 PE=1 SV=3"	"0.000"	""	"5"	"2"	"4"	"2"	"351"	"38.6"	"4.96"	"849.51"	"7.39"	"2"	"2"	"cell-cell signaling;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00170"	"468"	"ENSG00000128272"	"ATF4"	"hsa:468; P18848; Q96AQ3; Q9UH31"	"Alzheimer's disease and miRNA effects; Myometrial relaxation and contraction pathways; Photodynamic therapy-induced unfolded protein response; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; mRNA, protein, and metabolite inducation pathway by cyclosporin A; PI3K-Akt signaling pathway; Nonalcoholic fatty liver disease; Joubert syndrome; Hepatitis B infection; Unfolded protein response; 7q11.23 copy number variation syndrome; Alzheimer's disease"	"NFE2L2 regulating anti-oxidant/detoxification enzymes; Response of EIF2AK1 (HRI) to heme deficiency; ATF4 activates genes in response to endoplasmic reticulum  stress; Response of EIF2AK4 (GCN2) to amino acid deficiency; ATF6 (ATF6-alpha) activates chaperone genes"	"20"	"0"	"418.4"	"363.8"	"331.6"	"342.0"	"312.4"	"300.1"	"415.1"	"519.2"	"496.2"	"707.1"	"740.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62899"	"60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1"	"0.000"	""	"18"	"2"	"4"	"2"	"125"	"14.5"	"10.54"	"707.43"	"7.35"	"2"	"2"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01198"	"6160"	"ENSG00000071082"	"RPL31"	"B7Z4K2; D3DVJ4; hsa:6160; P12947; P62899; Q53SQ5; Q6IRZ0; Q6LBJ6"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"210.4"	"157.3"	"200.1"	"162.8"	"172.4"	"185.0"	"261.1"	"379.5"	"357.0"	"820.3"	"1181.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P41567"	"Eukaryotic translation initiation factor 1 OS=Homo sapiens OX=9606 GN=EIF1 PE=1 SV=1"	"0.000"	""	"24"	"2"	"4"	"1"	"113"	"12.7"	"7.44"	"693.88"	"7.33"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf01253"	"10209"	"ENSG00000173812"	"EIF1"	"hsa:10209; P41567; Q9UNQ9"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IVM0"	"Coiled-coil domain-containing protein 50 OS=Homo sapiens OX=9606 GN=CCDC50 PE=1 SV=1"	"0.000"	""	"7"	"2"	"4"	"2"	"306"	"35.8"	"6.65"	"852.06"	"7.31"	"2"	"2"	"other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf15295"	"152137"	"ENSG00000152492"	"CCDC50"	"hsa:152137; Q86VH7; Q8IVM0"	""	""	"0"	"0"	"111.2"	"113.9"	"117.8"	"109.6"	"109.3"	"115.7"	"154.0"	"399.0"	"397.1"	"728.0"	"869.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07947"	"Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3"	"0.000"	""	"6"	"3"	"4"	"2"	"543"	"60.8"	"6.74"	"970.54"	"7.29"	"2"	"2"	"protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi"	"signal transduction activity or receptor binding;kinase activity;other molecular function"	"Pf00017, Pf00018, Pf07714"	"7525"	"ENSG00000176105"	"YES1"	"A6NLB3; D3DUH1; hsa:7525; P07947"	"Thymic stromal lymphopoietin (TSLP) signaling pathway; Interleukin-11 signaling pathway; NRF2-ARE regulation; Gastrin signaling pathway; GDNF signaling"	"FCGR activation; FCGR3A-mediated IL10 synthesis; FCGR3A-mediated phagocytosis; Regulation of signaling by CBL; EPHB-mediated forward signaling; Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants; Regulation of KIT signaling; Signaling by ERBB2; EPH-ephrin mediated repulsion of cells; EPHA-mediated growth cone collapse; Signaling by CSF1 (M-CSF) in myeloid cells; RUNX2 regulates osteoblast differentiation; CD28 co-stimulation; PECAM1 interactions; CTLA4 inhibitory signaling"	"22"	"1"	"142.0"	"114.5"	"137.7"	"127.2"	"154.4"	"139.9"	"171.9"	"317.5"	"331.5"	"852.0"	"1523.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BQ39"	"ATP-dependent RNA helicase DDX50 OS=Homo sapiens OX=9606 GN=DDX50 PE=1 SV=1"	"0.000"	""	"5"	"3"	"5"	"2"	"737"	"82.5"	"9.17"	"984.14"	"7.29"	"3"	"2"	""	"plasma membrane;other membranes;nucleus"	"other molecular function"	"Pf00270, Pf00271, Pf08152"	"79009"	"ENSG00000107625"	"DDX50"	"hsa:79009; Q5VX37; Q8WV76; Q9BQ39; Q9BWI8"	""	""	"0"	"0"	"73.4"	"58.2"	"97.0"	"87.6"	"87.0"	"80.6"	"102.1"	"153.6"	"153.6"	"371.4"	"597.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P47755"	"F-actin-capping protein subunit alpha-2 OS=Homo sapiens OX=9606 GN=CAPZA2 PE=1 SV=3"	"0.000"	""	"13"	"2"	"4"	"2"	"286"	"32.9"	"5.85"	"861.56"	"7.28"	"2"	"2"	"cell organization and biogenesis"	"non-structural extracellular;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf01267"	"830"	"ENSG00000198898"	"CAPZA2"	"B4DG50; hsa:830; P47755"	""	"MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Sensory processing of sound by inner hair cells of the cochlea; Factors involved in megakaryocyte development and platelet production; Advanced glycosylation endproduct receptor signaling"	"7"	"0"	"12.6"	"9.2"	"15.8"	"12.4"	"15.3"	"16.6"	"17.5"	"37.1"	"35.0"	"131.0"	"198.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95881"	"Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1"	"0.000"	""	"21"	"4"	"5"	"4"	"172"	"19.2"	"5.40"	"1078.38"	"7.28"	"3"	"2"	"other biological processes"	"ER/Golgi"	"other molecular function"	"Pf13899"	"51060"	"ENSG00000117862"	"TXNDC12"	"B3KQS0; hsa:51060; O95881; Q5T1T4; Q96H50"	""	""	"0"	"0"	"862.4"	"651.9"	"928.8"	"892.3"	"891.9"	"880.6"	"1120.7"	"1471.8"	"1298.7"	"1851.5"	"2139.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P38432"	"Coilin OS=Homo sapiens OX=9606 GN=COIL PE=1 SV=1"	"0.000"	""	"4"	"2"	"4"	"2"	"576"	"62.6"	"9.07"	"807.33"	"7.28"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf15862"	"8161"	"ENSG00000121058"	"COIL"	"B2R931; hsa:8161; P38432"	""	""	"0"	"0"	"105.9"	"97.5"	"91.0"	"97.8"	"94.2"	"94.7"	"124.2"	"230.5"	"221.8"	"386.5"	"444.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P58107"	"Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3"	"0.000"	""	"2"	"2"	"3"	"1"	"5088"	"555.3"	"5.62"	"571.49"	"7.27"	"1"	"2"	"cell organization and biogenesis;stress response;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00681"	"83481"	"ENSG00000261150"	"EPPK1"	"A0A087X1U6; hsa:83481; P58107; Q76E58; Q9NSU9"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14697"	"Neutral alpha-glucosidase AB OS=Homo sapiens OX=9606 GN=GANAB PE=1 SV=3"	"0.000"	""	"3"	"2"	"3"	"2"	"944"	"106.8"	"6.14"	"474.44"	"7.25"	"1"	"2"	"protein metabolism;other metabolic processes"	"ER/Golgi;other cell component"	"other molecular function"	"Pf01055, Pf13802"	"23193"	"ENSG00000089597"	"GANAB"	"A6NC20; hsa:23193; Q14697; Q8WTS9; Q9P0X0"	"N-glycan biosynthesis"	"Maturation of spike protein; Calnexin/calreticulin cycle; Maturation of spike protein"	"5"	"0"	"67.0"	"59.9"	"44.2"	"49.5"	"48.3"	"49.2"	"74.6"	"112.5"	"114.8"	"180.3"	"289.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96SB8"	"Structural maintenance of chromosomes protein 6 OS=Homo sapiens OX=9606 GN=SMC6 PE=1 SV=2"	"0.000"	""	"3"	"3"	"5"	"3"	"1091"	"126.2"	"6.99"	"1124.56"	"7.25"	"3"	"2"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02463"	"79677"	"ENSG00000163029"	"SMC6"	"A8K8Q6; D6W518; hsa:79677; Q05BV4; Q96SB8; Q9H0X3; Q9H6M0"	""	"SUMOylation of DNA damage response and repair proteins"	"1"	"0"	"24.4"	"21.9"	"29.0"	"29.1"	"29.7"	"26.8"	"48.2"	"82.4"	"89.1"	"278.3"	"358.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NB78"	"Lysine-specific histone demethylase 1B OS=Homo sapiens OX=9606 GN=KDM1B PE=1 SV=3"	"0.000"	""	"5"	"3"	"5"	"3"	"822"	"92.0"	"7.87"	"1380.25"	"7.24"	"3"	"2"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf01593, Pf04433, Pf07496"	"221656"	"ENSG00000165097"	"KDM1B"	"A2A2C5; A2A2C6; hsa:221656; Q5TGV3; Q6AI15; Q6ZUU4; Q8N258; Q8NB78; Q96EL7"	"Vitamin D-sensitive calcium signaling in depression"	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux; UCH proteinases; HDMs demethylate histones"	"4"	"0"	"66.9"	"57.8"	"57.6"	"56.3"	"53.9"	"77.7"	"85.3"	"275.2"	"281.9"	"717.9"	"834.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UPN9"	"E3 ubiquitin-protein ligase TRIM33 OS=Homo sapiens OX=9606 GN=TRIM33 PE=1 SV=3"	"0.000"	""	"2"	"2"	"3"	"2"	"1127"	"122.5"	"6.67"	"323.46"	"7.24"	"1"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00439, Pf00628, Pf00643, Pf13445"	"51592"	"ENSG00000197323"	"TRIM33"	"hsa:51592; O95855; Q5TG72; Q5TG73; Q5TG74; Q9C017; Q9UJ79; Q9UPN9"	"Ectoderm differentiation"	"Downregulation of SMAD2/3:SMAD4 transcriptional activity; Germ layer formation at gastrulation"	"3"	"0"	"61.8"	"61.2"	"63.9"	"64.3"	"57.8"	"41.6"	"75.5"	"121.8"	"102.8"	"222.9"	"296.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UNS1"	"Protein timeless homolog OS=Homo sapiens OX=9606 GN=TIMELESS PE=1 SV=2"	"0.000"	""	"2"	"2"	"4"	"2"	"1208"	"138.6"	"5.40"	"747.58"	"7.23"	"2"	"2"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04821, Pf05029"	"8914"	"ENSG00000111602"	"TIMELESS"	"B2ZAV0; hsa:8914; O94802; Q86VM1; Q8IWH3; Q9UNS1"	""	"Processing of DNA double-strand break ends"	"1"	"0"	"15.5"	"12.7"	"14.0"	"15.7"	"10.1"	"13.4"	"24.8"	"34.5"	"34.2"	"166.5"	"311.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00232"	"26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3"	"0.000"	""	"7"	"2"	"3"	"2"	"456"	"52.9"	"7.65"	"408.04"	"7.23"	"1"	"2"	"protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	""	"Pf01399, Pf18098"	"5718"	"ENSG00000197170"	"PSMD12"	"A6NP15; hsa:5718; O00232; Q53HA2; Q6P053"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Ciliary landscape; Alzheimer's disease"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"65"	"0"	"14.2"	"10.2"	"7.8"	"8.9"	"11.2"	"8.6"	"16.8"	"22.0"	"27.7"	"89.2"	"179.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q03001"	"Dystonin OS=Homo sapiens OX=9606 GN=DST PE=1 SV=4"	"0.000"	""	"0"	"3"	"5"	"1"	"7570"	"860.1"	"5.25"	"1219.55"	"7.22"	"3"	"2"	"cell adhesion;cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"extracellular matrix;plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00307, Pf00435, Pf00681, Pf02187, Pf13499, Pf17902, Pf18373"	"667"	"ENSG00000151914"	"DST"	"B7Z3H1; E7ERU0; hsa:667; O94833; Q03001; Q12825; Q13266; Q13267; Q13775; Q5TBT0; Q5TBT2; Q5TF23; Q5TF24; Q8N1T8; Q8N8J3; Q8WXK8; Q8WXK9; Q96AK9; Q96DQ5; Q96J76; Q96QT5; Q9H555; Q9UGD7; Q9UGD8; Q9UN10"	""	"RND1 GTPase cycle; RND2 GTPase cycle; RHOV GTPase cycle; RHOU GTPase cycle; RND3 GTPase cycle; Type I hemidesmosome assembly"	"6"	"1"	"90.6"	"65.6"	"89.6"	"73.6"	"85.2"	"77.5"	"116.3"	"187.9"	"222.2"	"429.9"	"547.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WXF0"	"Serine/arginine-rich splicing factor 12 OS=Homo sapiens OX=9606 GN=SRSF12 PE=2 SV=1"	"0.000"	""	"10"	"2"	"4"	"1"	"261"	"30.5"	"11.69"	"842.75"	"7.21"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00076"	"135295"	"ENSG00000154548"	"SRSF12"	"B2RA22; hsa:135295; Q5T7K0; Q8WW25; Q8WXF0"	""	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"2"	"0"	"28.7"	"18.3"	"26.7"	"27.5"	"23.8"	"28.3"	"36.5"	"49.7"	"42.4"	"75.9"	"95.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBB9"	"Tuftelin-interacting protein 11 OS=Homo sapiens OX=9606 GN=TFIP11 PE=1 SV=1"	"0.000"	""	"3"	"2"	"4"	"2"	"837"	"96.8"	"5.67"	"742.64"	"7.19"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"extracellular matrix;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01585, Pf07842, Pf12457"	"24144"	"ENSG00000100109"	"TFIP11"	"hsa:24144; O95908; Q20WL0; Q5H8V8; Q9UBB9; Q9UGV7; Q9Y2Q8"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"28.2"	"33.8"	"34.1"	"25.0"	"36.0"	"36.2"	"37.6"	"62.4"	"51.6"	"152.8"	"229.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WVK2"	"U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP27 PE=1 SV=1"	"0.000"	""	"19"	"2"	"4"	"2"	"155"	"18.8"	"11.62"	"683.00"	"7.18"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf08648"	"11017"	"ENSG00000124380"	"SNRNP27"	"hsa:11017; Q15410; Q8WVK2"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"75.6"	"53.1"	"70.3"	"68.5"	"53.6"	"63.2"	"79.6"	"201.4"	"209.1"	"568.3"	"635.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BRP8"	"Partner of Y14 and mago OS=Homo sapiens OX=9606 GN=PYM1 PE=1 SV=1"	"0.000"	""	"15"	"2"	"5"	"2"	"204"	"22.6"	"9.45"	"956.98"	"7.15"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity"	"Pf09282"	"84305"	"ENSG00000170473"	"PYM1"	"B6ZDM5; hsa:84305; Q8IXJ8; Q8N8E7; Q9BRP8"	"TAR syndrome"	""	"1"	"0"	"46.1"	"38.7"	"51.1"	"47.9"	"44.5"	"48.2"	"69.3"	"89.7"	"91.2"	"172.7"	"204.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95251"	"Histone acetyltransferase KAT7 OS=Homo sapiens OX=9606 GN=KAT7 PE=1 SV=1"	"0.000"	""	"6"	"2"	"3"	"2"	"611"	"70.6"	"8.85"	"249.18"	"7.13"	"1"	"2"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01530, Pf01853, Pf17772"	"11143"	"ENSG00000136504"	"KAT7"	"B3KN74; B4DF85; B4DFB4; B4DFE0; B4DGY4; E7ER15; G5E9K7; hsa:11143; O95251"	"Androgen receptor signaling pathway"	"HATs acetylate histones"	"2"	"0"	"13.8"	"4.1"	"12.2"	"13.9"	"10.3"	"9.0"	"11.2"	"25.6"	"19.9"	"60.9"	"66.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05386"	"60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1"	"0.000"	""	"34"	"3"	"6"	"2"	"114"	"11.5"	"4.32"	"1518.06"	"7.13"	"3"	"2"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00428"	"6176"	"ENSG00000137818"	"RPLP1"	"A6NIB2; hsa:6176; P05386"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"269.7"	"183.3"	"301.4"	"278.0"	"234.1"	"231.8"	"358.4"	"716.2"	"604.8"	"1511.6"	"2504.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62306"	"Small nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=SNRPF PE=1 SV=1"	"0.000"	""	"15"	"1"	"4"	"1"	"86"	"9.7"	"4.67"	"785.18"	"7.12"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01423"	"6636"	"ENSG00000139343"	"SNRPF"	"A2VCR2; B2R498; hsa:6636; P62306; Q15356; Q6IBQ1; Q6P4I0"	"mRNA processing"	"snRNP Assembly; RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway; SARS-CoV-2 modulates host translation machinery; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"8"	"0"	"21.5"	"25.4"	"27.6"	"29.7"	"26.3"	"24.1"	"33.5"	"51.0"	"51.6"	"100.9"	"187.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H0E9"	"Bromodomain-containing protein 8 OS=Homo sapiens OX=9606 GN=BRD8 PE=1 SV=2"	"0.000"	""	"2"	"2"	"4"	"2"	"1235"	"135.3"	"4.60"	"776.53"	"7.12"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00439"	"10902"	"ENSG00000112983"	"BRD8"	"hsa:10902; O43178; Q15355; Q58AB0; Q59GN0; Q969M9; Q9H0E9"	""	"HATs acetylate histones"	"1"	"0"	"95.2"	"74.9"	"99.9"	"93.9"	"97.5"	"85.7"	"106.5"	"179.8"	"166.4"	"314.7"	"421.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P53992"	"Protein transport protein Sec24C OS=Homo sapiens OX=9606 GN=SEC24C PE=1 SV=3"	"0.000"	""	"2"	"2"	"4"	"2"	"1094"	"118.2"	"7.06"	"684.55"	"7.12"	"2"	"2"	"cell organization and biogenesis;transport;developmental processes"	"other membranes;cytosol;ER/Golgi"	"other molecular function"	"Pf00626, Pf04810, Pf04811, Pf04815, Pf08033"	"9632"	"ENSG00000176986"	"SEC24C"	"B4DZT4; hsa:9632; P53992; Q8WV25"	"Sterol regulatory element-binding proteins (SREBP) signaling"	"COPII-mediated vesicle transport; MHC class II antigen presentation; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Cargo concentration in the ER; Regulation of cholesterol biosynthesis by SREBP (SREBF)"	"7"	"0"	"63.4"	"59.2"	"73.7"	"62.3"	"68.9"	"64.1"	"81.5"	"140.8"	"149.8"	"360.8"	"602.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IY63"	"Angiomotin-like protein 1 OS=Homo sapiens OX=9606 GN=AMOTL1 PE=1 SV=1"	"0.000"	""	"3"	"3"	"6"	"1"	"956"	"106.5"	"7.11"	"741.81"	"7.12"	"3"	"3"	"cell-cell signaling;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf12240"	"154810"	"ENSG00000166025"	"AMOTL1"	"hsa:154810; Q63HK7; Q8IY63; Q8NDN0; Q8TEN8; Q8WXD1; Q96CM5"	""	"Signaling by Hippo"	"1"	"0"	"8.1"	"13.9"	"5.4"	"7.4"	"6.9"	"5.4"	"4.4"	"10.6"	"9.1"	"32.5"	"50.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BQ24"	"Zinc finger FYVE domain-containing protein 21 OS=Homo sapiens OX=9606 GN=ZFYVE21 PE=1 SV=1"	"0.000"	""	"15"	"2"	"3"	"2"	"234"	"26.5"	"8.41"	"360.73"	"7.11"	"1"	"2"	""	"other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01363, Pf16696"	"79038"	"ENSG00000100711"	"ZFYVE21"	"A8K3A4; hsa:79038; Q86T05; Q96LT1; Q9BQ24"	""	""	"0"	"0"	"16.2"	"14.0"	"20.1"	"20.8"	"12.7"	"18.4"	"23.5"	"35.3"	"38.6"	"58.7"	"68.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13409"	"Cytoplasmic dynein 1 intermediate chain 2 OS=Homo sapiens OX=9606 GN=DYNC1I2 PE=1 SV=3"	"0.000"	""	"3"	"1"	"4"	"1"	"638"	"71.4"	"5.20"	"629.42"	"7.10"	"1"	"1"	"transport;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400, Pf11540"	"1781"	"ENSG00000077380"	"DYNC1I2"	"B7ZA04; D3DPD4; D3DPD5; D3DPD6; hsa:1781; Q13409; Q32LY9; Q53S84; Q5BJF8; Q7Z4X1; Q96NG7; Q96S87; Q9BXZ5; Q9NT58"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein"	"HCMV Early Events; MHC class II antigen presentation; Separation of Sister Chromatids; Aggrephagy; Regulation of PLK1 Activity at G2/M Transition; RHO GTPases Activate Formins; COPI-mediated anterograde transport; Resolution of Sister Chromatid Cohesion; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Recruitment of NuMA to mitotic centrosomes; COPI-independent Golgi-to-ER retrograde traffic; EML4 and NUDC in mitotic spindle formation; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"21"	"0"	"61.5"	"44.5"	"52.2"	"41.3"	"50.8"	"43.4"	"66.3"	"89.4"	"96.9"	"211.7"	"337.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5L4"	"Mitochondrial import inner membrane translocase subunit Tim13 OS=Homo sapiens OX=9606 GN=TIMM13 PE=1 SV=1"	"0.000"	""	"12"	"1"	"4"	"1"	"95"	"10.5"	"8.18"	"625.27"	"7.05"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf02953"	"26517"	"ENSG00000099800"	"TIMM13"	"hsa:26517; P62206; Q9UHL8; Q9WTL1; Q9Y5L4"	""	"Mitochondrial protein import"	"1"	"0"	"44.0"	"22.0"	"41.3"	"33.0"	"39.2"	"44.7"	"68.8"	"135.6"	"140.2"	"371.2"	"650.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EY1"	"DnaJ homolog subfamily A member 3, mitochondrial OS=Homo sapiens OX=9606 GN=DNAJA3 PE=1 SV=2"	"0.000"	""	"5"	"2"	"3"	"2"	"480"	"52.5"	"9.26"	"511.99"	"7.04"	"1"	"2"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00226, Pf00684, Pf01556"	"9093"	"ENSG00000103423; ENSG00000276726"	"DNAJA3"	"B2RAJ5; B4DI33; E7ES32; hsa:9093; O75472; Q8WUJ6; Q8WXJ3; Q96D76; Q96EY1; Q96IV1; Q9NYH8"	""	""	"0"	"0"	"47.9"	"34.3"	"51.7"	"48.0"	"56.6"	"48.2"	"63.9"	"123.3"	"114.1"	"222.8"	"280.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75489"	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS3 PE=1 SV=1"	"0.000"	""	"16"	"3"	"5"	"3"	"264"	"30.2"	"7.50"	"1375.36"	"7.03"	"3"	"2"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion;nucleus"	"transporter activity;other molecular function"	"Pf00329"	"4722"	"ENSG00000213619; ENSG00000285387"	"NDUFS3"	"B2R9J1; B4DFM8; hsa:4722; O75489; Q9UNQ8"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"RHOG GTPase cycle; Complex I biogenesis"	"6"	"0"	"142.0"	"108.0"	"134.2"	"113.8"	"108.5"	"132.8"	"190.8"	"395.9"	"410.2"	"1071.0"	"1321.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86UK7"	"E3 ubiquitin-protein ligase ZNF598 OS=Homo sapiens OX=9606 GN=ZNF598 PE=1 SV=1"	"0.000"	""	"4"	"2"	"3"	"2"	"904"	"98.6"	"8.40"	"370.10"	"7.01"	"1"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus"	"enzyme regulator activity;translation activity;other molecular function"	""	"90850"	""	"ZNF598"	"hsa:90850; Q86UK7; Q8IW49; Q8N3D9; Q96FG3; Q9H7J3"	""	""	"0"	"0"	"23.4"	"21.4"	"22.3"	"26.0"	"25.2"	"24.4"	"24.8"	"41.7"	"37.9"	"71.6"	"59.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7RTP6"	"[F-actin]-monooxygenase MICAL3 OS=Homo sapiens OX=9606 GN=MICAL3 PE=1 SV=2"	"0.000"	""	"1"	"2"	"4"	"2"	"2002"	"224.2"	"5.55"	"805.13"	"6.99"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00412, Pf01494, Pf12130"	"57553"	"ENSG00000243156"	"MICAL3"	"B2RXJ5; E9PEF0; hsa:57553; O94909; Q5U4P4; Q6ICK4; Q7RTP6; Q96DF2; Q9P2I3"	""	""	"0"	"0"	"12.8"	"15.5"	"15.9"	"16.3"	"14.7"	"12.9"	"15.7"	"15.7"	"21.4"	"55.5"	"67.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NP79"	"Vacuolar protein sorting-associated protein VTA1 homolog OS=Homo sapiens OX=9606 GN=VTA1 PE=1 SV=1"	"0.000"	""	"9"	"2"	"4"	"2"	"307"	"33.9"	"6.29"	"678.55"	"6.99"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	""	"Pf04652, Pf18097"	"51534"	"ENSG00000009844"	"VTA1"	"B4DW55; E1P594; E7ETQ7; hsa:51534; Q5TGM1; Q6IAE8; Q9H0R2; Q9H3K9; Q9NP79; Q9P0Q0"	""	"Budding and maturation of HIV virion; Endosomal Sorting Complex Required For Transport (ESCRT)"	"2"	"0"	"40.8"	"24.9"	"37.8"	"38.5"	"37.6"	"35.5"	"48.5"	"78.0"	"56.9"	"414.0"	"987.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P54727"	"UV excision repair protein RAD23 homolog B OS=Homo sapiens OX=9606 GN=RAD23B PE=1 SV=1"	"0.000"	""	"6"	"2"	"3"	"2"	"409"	"43.1"	"4.84"	"422.64"	"6.98"	"1"	"2"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00240, Pf00627, Pf09280"	"5887"	"ENSG00000119318"	"RAD23B"	"B3KWK8; G5E9P0; hsa:5887; P54727; Q7Z5K8; Q8WUB0"	"Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle; Formation of Incision Complex in GG-NER; Josephin domain DUBs; DNA Damage Recognition in GG-NER"	"7"	"0"	"230.4"	"201.3"	"245.9"	"206.2"	"238.4"	"235.5"	"279.3"	"425.0"	"412.9"	"676.7"	"966.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NCN4"	"E3 ubiquitin-protein ligase RNF169 OS=Homo sapiens OX=9606 GN=RNF169 PE=1 SV=2"	"0.000"	""	"5"	"3"	"5"	"3"	"708"	"77.1"	"9.10"	"972.66"	"6.98"	"3"	"2"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf13920"	"254225"	"ENSG00000166439"	"RNF169"	"hsa:254225; Q6N015; Q8NCN4"	""	""	"0"	"0"	"242.8"	"280.2"	"165.6"	"204.7"	"196.0"	"216.8"	"251.3"	"295.2"	"292.8"	"418.1"	"504.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14737"	"Programmed cell death protein 5 OS=Homo sapiens OX=9606 GN=PDCD5 PE=1 SV=3"	"0.000"	""	"18"	"2"	"4"	"2"	"125"	"14.3"	"6.04"	"765.27"	"6.94"	"2"	"2"	"other biological processes"	"cytosol;nucleus"	"enzyme regulator activity;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf01984"	"9141"	"ENSG00000105185"	"PDCD5"	"B4DE64; hsa:9141; O14737; Q53YC9; Q6IB70"	""	""	"0"	"0"	"173.3"	"149.4"	"186.1"	"162.4"	"164.3"	"179.7"	"187.8"	"287.2"	"250.4"	"588.3"	"1569.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2Q3"	"Glutathione S-transferase kappa 1 OS=Homo sapiens OX=9606 GN=GSTK1 PE=1 SV=3"	"0.000"	""	"9"	"2"	"4"	"2"	"226"	"25.5"	"8.41"	"833.95"	"6.92"	"2"	"2"	"other metabolic processes;other biological processes"	"cytosol;mitochondrion;other cytoplasmic organelle"	"other molecular function"	"Pf01323"	"373156"	"ENSG00000197448"	"GSTK1"	"B4DIH1; B4DSY2; hsa:373156; Q6P4H0; Q7Z520; Q9P1S4; Q9Y2Q3"	"Metapathway biotransformation Phase I and II"	"Peroxisomal protein import; Glutathione conjugation"	"3"	"0"	"53.3"	"35.0"	"56.9"	"62.4"	"63.8"	"70.2"	"88.3"	"225.9"	"256.1"	"814.7"	"1013.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14136"	"Glial fibrillary acidic protein OS=Homo sapiens OX=9606 GN=GFAP PE=1 SV=1"	"0.000"	""	"8"	"3"	"4"	"1"	"432"	"49.9"	"5.52"	"309.51"	"6.91"	"1"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00038, Pf04732"	"2670"	"ENSG00000131095"	"GFAP"	"A7REI1; B2RD44; D3DX59; E9PAX3; hsa:2670; P14136; Q53H98; Q5D055; Q6ZQS3; Q7Z5J6; Q7Z5J7; Q96KS4; Q96P18; Q9UFD0"	"Neural crest differentiation; Spinal cord injury; Neuroinflammation and glutamatergic signaling"	"Nuclear signaling by ERBB4; Chaperone Mediated Autophagy"	"5"	"0"	"13.2"	"17.4"	"7.4"	"8.0"	"10.7"	"13.4"	"14.9"	"39.1"	"42.9"	"108.8"	"176.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9GZT9"	"Egl nine homolog 1 OS=Homo sapiens OX=9606 GN=EGLN1 PE=1 SV=1"	"0.000"	""	"6"	"2"	"4"	"2"	"426"	"46.0"	"8.53"	"816.72"	"6.91"	"2"	"2"	"protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01753, Pf13640"	"54583"	"ENSG00000135766"	"EGLN1"	"hsa:54583; Q8N3M8; Q9BZS8; Q9BZT0; Q9GZT9"	"Photodynamic therapy-induced HIF-1 survival signaling; Type 2 papillary renal cell carcinoma; Markers of kidney cell lineage"	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"	"4"	"0"	"124.7"	"117.3"	"110.3"	"111.7"	"121.9"	"106.2"	"138.1"	"225.5"	"189.4"	"351.2"	"460.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z3K3"	"Pogo transposable element with ZNF domain OS=Homo sapiens OX=9606 GN=POGZ PE=1 SV=2"	"0.000"	""	"2"	"2"	"4"	"2"	"1410"	"155.2"	"7.40"	"679.42"	"6.91"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03184, Pf03221"	"23126"	"ENSG00000143442"	"POGZ"	"B4DTP8; B4DYL9; B7ZBY5; E9PM80; hsa:23126; O75049; Q3LIC4; Q5SZS1; Q5SZS2; Q5SZS3; Q5SZS4; Q7Z3K3; Q8TDZ7; Q9Y4X7"	""	""	"0"	"0"	"48.9"	"46.0"	"46.0"	"42.6"	"49.4"	"40.7"	"56.8"	"74.3"	"70.3"	"122.3"	"175.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15003"	"Condensin complex subunit 2 OS=Homo sapiens OX=9606 GN=NCAPH PE=1 SV=3"	"0.000"	""	"3"	"2"	"4"	"2"	"741"	"82.5"	"5.06"	"826.32"	"6.90"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf05786"	"23397"	"ENSG00000121152"	"NCAPH"	"B4E189; hsa:23397; Q15003; Q8TB87"	"2q11.2 copy number variation syndrome"	"Condensation of Prometaphase Chromosomes"	"2"	"0"	"61.5"	"55.3"	"74.1"	"77.3"	"74.8"	"69.4"	"88.8"	"163.6"	"160.0"	"305.5"	"379.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00471"	"Exocyst complex component 5 OS=Homo sapiens OX=9606 GN=EXOC5 PE=1 SV=1"	"0.000"	""	"4"	"2"	"4"	"2"	"708"	"81.8"	"6.71"	"583.93"	"6.88"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf07393"	"10640"	"ENSG00000070367"	"EXOC5"	"B2R6C5; hsa:10640; O00471; Q8IW24"	"Ciliary landscape"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"4"	"0"	"22.1"	"13.0"	"20.9"	"17.9"	"15.2"	"24.8"	"31.8"	"120.2"	"131.9"	"300.3"	"361.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y262"	"Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1"	"0.000"	""	"4"	"2"	"3"	"2"	"564"	"66.7"	"6.34"	"427.72"	"6.84"	"1"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity"	"Pf10255"	"51386"	"ENSG00000100129"	"EIF3L"	"B2RDG6; B4DYB2; G8JLH4; hsa:51386; Q53HQ1; Q53HT4; Q5QTR1; Q5TI15; Q6ICD2; Q9Y262"	""	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition"	"6"	"0"	"14.4"	"15.9"	"27.9"	"24.3"	"24.0"	"29.5"	"28.2"	"59.0"	"70.2"	"131.7"	"316.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99536"	"Synaptic vesicle membrane protein VAT-1 homolog OS=Homo sapiens OX=9606 GN=VAT1 PE=1 SV=2"	"0.000"	""	"8"	"2"	"4"	"2"	"393"	"41.9"	"6.29"	"953.19"	"6.80"	"2"	"2"	"other biological processes"	"non-structural extracellular;other membranes;mitochondrion;other cytoplasmic organelle"	"other molecular function"	"Pf08240, Pf13602"	"10493"	"ENSG00000108828"	"VAT1"	"A8K345; B0AZP7; B4DPX4; hsa:10493; Q13035; Q5BKZ7; Q96A39; Q99536; Q9BUT8"	""	"Neutrophil degranulation"	"1"	"0"	"110.1"	"60.2"	"103.0"	"100.9"	"90.7"	"90.4"	"125.7"	"257.1"	"285.2"	"600.6"	"614.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O96017"	"Serine/threonine-protein kinase Chk2 OS=Homo sapiens OX=9606 GN=CHEK2 PE=1 SV=1"	"0.000"	""	"5"	"2"	"3"	"2"	"543"	"60.9"	"5.91"	"411.47"	"6.80"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"ER/Golgi;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00498"	"11200"	"ENSG00000183765"	"CHEK2"	"A8K3Y9; B7ZBF3; B7ZBF4; B7ZBF5; hsa:11200; O96017; Q6QA03; Q6QA04; Q6QA05; Q6QA06; Q6QA07; Q6QA08; Q6QA10; Q6QA11; Q6QA12; Q6QA13; Q9HBS5; Q9HCQ8; Q9UGF0; Q9UGF1"	"miRNA regulation of DNA damage response; Cell cycle; ATM signaling in development and disease ; miRNA regulation of p53 pathway in prostate cancer; DNA damage response"	"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Regulation of TP53 Degradation; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Regulation of TP53 Activity through Phosphorylation; Regulation of TP53 Activity through Methylation; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; Stabilization of p53"	"13"	"0"	"31.2"	"13.8"	"35.0"	"29.6"	"33.2"	"27.8"	"29.5"	"91.6"	"97.3"	"302.8"	"458.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TDN4"	"CDK5 and ABL1 enzyme substrate 1 OS=Homo sapiens OX=9606 GN=CABLES1 PE=1 SV=2"	"0.000"	""	"4"	"2"	"4"	"2"	"633"	"67.6"	"9.17"	"975.10"	"6.79"	"2"	"2"	"cell cycle OR cell proliferation;developmental processes;other biological processes"	"cytosol;nucleus"	""	"Pf00134"	"91768"	"ENSG00000134508"	"CABLES1"	"B4DK60; hsa:91768; Q8N3Y8; Q8NA22; Q8TDN4; Q9BTG1"	""	"Factors involved in megakaryocyte development and platelet production; Cyclin E associated events during G1/S transition ; Cyclin A:Cdk2-associated events at S phase entry"	"3"	"0"	"11.9"	"5.8"	"8.2"	"7.7"	"8.3"	"39.8"	"87.4"	"184.7"	"165.5"	"224.9"	"222.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P28288"	"ATP-binding cassette sub-family D member 3 OS=Homo sapiens OX=9606 GN=ABCD3 PE=1 SV=1"	"0.000"	""	"3"	"3"	"6"	"2"	"659"	"75.4"	"9.36"	"892.33"	"6.79"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf00005, Pf06472"	"5825"	"ENSG00000117528"	"ABCD3"	"D3DT46; hsa:5825; P28288; Q15271; Q6NUN5; Q96DA3; Q9H529"	"Nuclear receptors in lipid metabolism and toxicity; Fragile X syndrome"	"RHOC GTPase cycle; RHOA GTPase cycle; Class I peroxisomal membrane protein import; ABC transporters in lipid homeostasis"	"6"	"1"	"330.7"	"273.8"	"314.9"	"276.8"	"277.8"	"253.8"	"378.5"	"783.3"	"783.1"	"1852.9"	"2239.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NRN9"	"rRNA N6-adenosine-methyltransferase METTL5 OS=Homo sapiens OX=9606 GN=METTL5 PE=1 SV=1"	"0.000"	""	"11"	"2"	"4"	"2"	"209"	"23.7"	"6.68"	"667.68"	"6.78"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05175"	"29081"	"ENSG00000138382"	"METTL5"	"D3DPC9; hsa:29081; Q9NRN9; Q9NVX1"	""	""	"0"	"0"	"61.4"	"41.4"	"56.7"	"59.5"	"69.2"	"60.5"	"81.1"	"276.4"	"301.5"	"869.7"	"1237.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61956"	"Small ubiquitin-related modifier 2 OS=Homo sapiens OX=9606 GN=SUMO2 PE=1 SV=3"	"0.000"	""	"23"	"2"	"3"	"2"	"95"	"10.9"	"5.50"	"328.01"	"6.77"	"1"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf11976"	"6613"	"ENSG00000188612"	"SUMO2"	"B2R4I2; hsa:6613; P55855; P61956; Q32Q42; Q6IPZ6; Q96HK1"	"TAR syndrome"	"SUMOylation of transcription cofactors; Formation of Incision Complex in GG-NER; SUMOylation of DNA damage response and repair proteins; Processing of DNA double-strand break ends; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; SUMOylation of intracellular receptors; Vitamin D (calciferol) metabolism; SUMOylation of transcription factors; SUMO is conjugated to E1 (UBA2:SAE1); SUMO is transferred from E1 to E2 (UBE2I, UBC9); SUMO is proteolytically processed"	"15"	"0"	"55.8"	"37.6"	"56.2"	"53.2"	"46.2"	"52.6"	"62.1"	"129.7"	"155.5"	"385.9"	"1184.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00257"	"E3 SUMO-protein ligase CBX4 OS=Homo sapiens OX=9606 GN=CBX4 PE=1 SV=3"	"0.000"	""	"4"	"1"	"4"	"1"	"560"	"61.3"	"9.36"	"688.31"	"6.77"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00385, Pf17218"	"8535"	"ENSG00000141582"	"CBX4"	"B1PJR7; hsa:8535; O00257; Q6TPI8; Q96C04"	""	"SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Oxidative Stress Induced Senescence; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Regulation of PTEN gene transcription"	"8"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q68CQ4"	"Digestive organ expansion factor homolog OS=Homo sapiens OX=9606 GN=DIEXF PE=1 SV=2"	"0.000"	""	"5"	"4"	"7"	"4"	"756"	"87.0"	"5.88"	"1529.58"	"6.74"	"4"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf06862"	"27042"	"ENSG00000117597"	"UTP25"	"hsa:27042; O75992; Q4VY00; Q63HL9; Q68CQ4"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"376.7"	"328.7"	"352.0"	"328.2"	"329.9"	"340.1"	"417.3"	"434.0"	"428.7"	"639.0"	"1016.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BXS6"	"Nucleolar and spindle-associated protein 1 OS=Homo sapiens OX=9606 GN=NUSAP1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"4"	"1"	"441"	"49.4"	"9.91"	"623.73"	"6.73"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity"	"Pf16006"	"51203"	"ENSG00000137804"	"NUSAP1"	"B4DDF1; E7ERR5; hsa:51203; J3KN21; Q53GW2; Q8TBT4; Q96E58; Q96FJ1; Q9BXS6; Q9GZM9; Q9NZ85; Q9UI70"	""	""	"0"	"0"	"29.0"	"18.3"	"42.0"	"36.9"	"32.5"	"34.8"	"48.3"	"188.5"	"192.6"	"419.0"	"473.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P12532"	"Creatine kinase U-type, mitochondrial OS=Homo sapiens OX=9606 GN=CKMT1A PE=1 SV=1"	"0.000"	""	"6"	"2"	"4"	"2"	"417"	"47.0"	"8.34"	"617.03"	"6.73"	"2"	"2"	"other metabolic processes"	"other membranes;mitochondrion"	"kinase activity;other molecular function"	"Pf00217, Pf02807"	"1159; 548596"	"ENSG00000223572; ENSG00000237289"	"CKMT1A; CKMT1B"	"B4DIT8; B7ZA09; hsa:1159; hsa:548596; P12532; Q0VAM3; Q32NF6; Q53FC4"	""	"Creatine metabolism"	"1"	"0"	"86.0"	"102.2"	"57.5"	"68.9"	"78.2"	"66.6"	"97.7"	"139.3"	"130.1"	"263.4"	"368.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N392"	"Rho GTPase-activating protein 18 OS=Homo sapiens OX=9606 GN=ARHGAP18 PE=1 SV=3"	"0.000"	""	"6"	"2"	"3"	"2"	"663"	"74.9"	"6.44"	"303.56"	"6.73"	"1"	"2"	"cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity"	"Pf00620"	"93663"	"ENSG00000146376"	"ARHGAP18"	"E1P575; hsa:93663; Q58EZ3; Q6P679; Q6PJD7; Q8N392; Q96S64"	""	"RHOC GTPase cycle; RHOA GTPase cycle"	"2"	"0"	"14.4"	"13.9"	"7.3"	"9.8"	"13.7"	"14.0"	"14.1"	"43.1"	"44.6"	"157.3"	"173.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P48047"	"ATP synthase subunit O, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PO PE=1 SV=1"	"0.000"	""	"12"	"2"	"4"	"2"	"213"	"23.3"	"9.96"	"705.51"	"6.72"	"2"	"2"	"other metabolic processes;transport"	"plasma membrane;other membranes;mitochondrion"	"transporter activity"	"Pf00213"	"539"	"ENSG00000241837"	"ATP5PO"	"B2R4E2; hsa:539; P48047; Q5U042; Q6IBI2"	"Electron transport chain: OXPHOS system in mitochondria; 7q11.23 copy number variation syndrome; Oxidative phosphorylation"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13200"	"26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3"	"0.000"	""	"3"	"2"	"4"	"2"	"908"	"100.1"	"5.20"	"708.07"	"6.70"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf01851, Pf17781, Pf18051"	"5708"	"ENSG00000175166"	"PSMD2"	"B4DX07; B4DXY1; E7EW34; E9PCS3; hsa:5708; Q12932; Q13200; Q15321; Q53XQ4; Q96I12"	"Proteasome degradation; Alzheimer's disease and miRNA effects; TNF-alpha signaling pathway; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"Neutrophil degranulation; Antigen processing: Ubiquitination & Proteasome degradation; FCERI mediated NF-kB activation; Downstream TCR signaling; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"65"	"0"	"84.6"	"78.8"	"100.1"	"100.6"	"92.8"	"83.7"	"120.6"	"191.4"	"190.3"	"419.1"	"750.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H9J2"	"39S ribosomal protein L44, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL44 PE=1 SV=1"	"0.000"	""	"6"	"2"	"4"	"2"	"332"	"37.5"	"8.40"	"589.51"	"6.69"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"plasma membrane;other membranes;mitochondrion;translational apparatus;nucleus"	"nucleic acid binding activity;other molecular function"	""	"65080"	"ENSG00000135900"	"MRPL44"	"hsa:65080; Q53S16; Q6IA62; Q9H821; Q9H9J2"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"164.2"	"126.2"	"189.3"	"175.4"	"183.6"	"181.3"	"229.9"	"358.2"	"357.9"	"600.3"	"931.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13356"	"RING-type E3 ubiquitin-protein ligase PPIL2 OS=Homo sapiens OX=9606 GN=PPIL2 PE=1 SV=1"	"0.000"	""	"4"	"2"	"4"	"2"	"520"	"58.8"	"8.78"	"737.72"	"6.67"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00160"	"23759"	"ENSG00000100023"	"PPIL2"	"hsa:23759; Q13356; Q13357; Q8TAH2; Q9BWR8"	""	"mRNA Splicing - Major Pathway; Basigin interactions"	"2"	"0"	"333.7"	"257.0"	"311.4"	"285.1"	"308.1"	"301.5"	"371.7"	"475.9"	"458.4"	"842.4"	"1079.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95391"	"Pre-mRNA-splicing factor SLU7 OS=Homo sapiens OX=9606 GN=SLU7 PE=1 SV=2"	"0.000"	""	"6"	"3"	"4"	"3"	"586"	"68.3"	"7.14"	"516.47"	"6.66"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;transport"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf11708"	"10569"	"ENSG00000164609"	"SLU7"	"D3DQK2; hsa:10569; O95391; Q3LUJ0; Q3LUJ1; Q6RXQ5; Q96FM9"	""	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"4"	"0"	"423.5"	"346.7"	"345.7"	"352.8"	"285.7"	"310.8"	"430.7"	"648.3"	"587.8"	"1075.9"	"1279.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q02252"	"Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial OS=Homo sapiens OX=9606 GN=ALDH6A1 PE=1 SV=2"	"0.000"	""	"4"	"2"	"4"	"2"	"535"	"57.8"	"8.50"	"905.67"	"6.65"	"2"	"2"	"other metabolic processes;other biological processes"	"mitochondrion;nucleus"	"other molecular function"	"Pf00171"	"4329"	"ENSG00000119711"	"ALDH6A1"	"B2R609; B4DFS8; hsa:4329; J3KNU8; Q02252; Q9UKM8"	""	"Branched-chain amino acid catabolism"	"1"	"0"	"66.3"	"63.4"	"64.6"	"64.2"	"63.5"	"71.2"	"85.9"	"151.1"	"154.0"	"312.2"	"465.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75122"	"CLIP-associating protein 2 OS=Homo sapiens OX=9606 GN=CLASP2 PE=1 SV=3"	"0.000"	""	"2"	"2"	"4"	"2"	"1294"	"141.0"	"8.40"	"728.91"	"6.65"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf12348"	"23122"	"ENSG00000163539"	"CLASP2"	"B2RTR1; F5H604; hsa:23122; O75122; Q7L8F6; Q8N6R6; Q9BQT3; Q9BQT4; Q9H7A3; Q9NSZ2"	"7q11.23 copy number variation syndrome"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Role of ABL in ROBO-SLIT signaling"	"8"	"0"	"15.5"	"19.6"	"19.1"	"21.1"	"17.9"	"22.7"	"28.5"	"31.0"	"35.7"	"69.7"	"83.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P40429"	"60S ribosomal protein L13a OS=Homo sapiens OX=9606 GN=RPL13A PE=1 SV=2"	"0.000"	""	"13"	"3"	"4"	"3"	"203"	"23.6"	"10.93"	"522.37"	"6.65"	"2"	"2"	"protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00572"	"23521"	"ENSG00000142541"	"RPL13A"	"A8K505; hsa:23521; P40429"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"15"	"0"	"232.3"	"213.9"	"233.8"	"188.2"	"190.9"	"231.5"	"305.2"	"467.9"	"498.7"	"1077.0"	"1729.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVM9"	"Integrator complex subunit 13 OS=Homo sapiens OX=9606 GN=INTS13 PE=1 SV=2"	"0.000"	""	"8"	"4"	"5"	"4"	"706"	"80.2"	"6.70"	"1046.33"	"6.64"	"3"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf10221"	"55726"	"ENSG00000064102"	"INTS13"	"B4DNK1; hsa:55726; Q86WE2; Q96HM2; Q9BTX2; Q9NTB6; Q9NVM5; Q9NVM9"	"1p36 copy number variation syndrome"	"RNA polymerase II transcribes snRNA genes"	"2"	"0"	"56.9"	"40.1"	"64.0"	"58.3"	"49.1"	"49.8"	"69.6"	"137.6"	"157.4"	"397.2"	"611.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15120"	"[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial OS=Homo sapiens OX=9606 GN=PDK3 PE=1 SV=1"	"0.000"	""	"7"	"2"	"4"	"2"	"406"	"46.9"	"8.37"	"871.85"	"6.64"	"2"	"2"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"mitochondrion;nucleus"	"kinase activity;other molecular function"	"Pf02518, Pf10436"	"5165"	"ENSG00000067992"	"PDK3"	"B4DXG6; hsa:5165; Q15120"	""	"Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid"	"2"	"0"	"109.4"	"89.0"	"112.2"	"118.9"	"96.3"	"120.4"	"128.3"	"279.2"	"324.4"	"623.5"	"671.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14554"	"Protein disulfide-isomerase A5 OS=Homo sapiens OX=9606 GN=PDIA5 PE=1 SV=1"	"0.000"	""	"4"	"2"	"4"	"2"	"519"	"59.6"	"7.91"	"807.17"	"6.64"	"2"	"2"	"protein metabolism;other metabolic processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf00085"	"10954"	"ENSG00000065485"	"PDIA5"	"D3DN95; hsa:10954; Q14554; Q9BV43"	""	"XBP1(S) activates chaperone genes"	"1"	"0"	"206.7"	"189.4"	"189.3"	"160.7"	"172.0"	"211.3"	"291.5"	"785.6"	"717.9"	"1020.8"	"994.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P587"	"Acylpyruvase FAHD1, mitochondrial OS=Homo sapiens OX=9606 GN=FAHD1 PE=1 SV=2"	"0.000"	""	"9"	"2"	"4"	"2"	"224"	"24.8"	"7.39"	"753.73"	"6.63"	"2"	"2"	"other metabolic processes"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf01557"	"81889"	"ENSG00000180185"	"FAHD1"	"B1AK40; B1AK41; hsa:81889; Q6FIC7; Q6P587; Q96RY1; Q9H0N6"	""	"Citric acid cycle (TCA cycle)"	"1"	"0"	"57.7"	"45.0"	"72.3"	"69.3"	"63.8"	"63.0"	"80.6"	"255.9"	"293.2"	"784.7"	"1176.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q49A26"	"Putative oxidoreductase GLYR1 OS=Homo sapiens OX=9606 GN=GLYR1 PE=1 SV=4"	"0.000"	""	"5"	"2"	"4"	"2"	"553"	"60.5"	"9.17"	"1125.31"	"6.62"	"2"	"2"	"cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00855, Pf03446, Pf14833"	"84656"	"ENSG00000140632"	"GLYR1"	"B4DL47; C9JJ40; C9JJ60; hsa:84656; Q49A26; Q5U632; Q6P1Q2; Q6V3W7; Q9BTI1; Q9BXK2"	""	""	"0"	"0"	"21.2"	"19.8"	"24.0"	"21.8"	"22.9"	"23.1"	"30.1"	"51.6"	"50.4"	"95.0"	"119.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2D4"	"Exocyst complex component 6B OS=Homo sapiens OX=9606 GN=EXOC6B PE=1 SV=3"	"0.000"	""	"5"	"3"	"4"	"3"	"811"	"94.1"	"6.46"	"801.79"	"6.62"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport"	"other cell component"	""	"Pf04091"	"23233"	"ENSG00000144036"	"EXOC6B"	"B8ZZY3; hsa:23233; Q9Y2D4"	"Ciliary landscape"	""	"1"	"0"	"22.4"	"21.0"	"29.4"	"25.1"	"23.5"	"33.4"	"50.2"	"155.1"	"153.6"	"300.8"	"378.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q53H47"	"Histone-lysine N-methyltransferase SETMAR OS=Homo sapiens OX=9606 GN=SETMAR PE=1 SV=2"	"0.000"	""	"6"	"3"	"4"	"3"	"684"	"78.0"	"7.14"	"612.54"	"6.59"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00856, Pf01359, Pf05033, Pf17906"	"6419"	"ENSG00000170364"	"SETMAR"	"B4DY74; E7EN68; hsa:6419; Q13579; Q1G668; Q53H47; Q96F41"	"Histone modifications"	""	"1"	"0"	"49.1"	"30.1"	"51.4"	"43.6"	"40.9"	"46.6"	"60.4"	"145.1"	"164.8"	"511.0"	"651.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96IY1"	"Kinetochore-associated protein NSL1 homolog OS=Homo sapiens OX=9606 GN=NSL1 PE=1 SV=3"	"0.000"	""	"10"	"2"	"4"	"2"	"281"	"32.1"	"6.79"	"658.38"	"6.59"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf08641"	"25936"	"ENSG00000117697"	"NSL1"	"E7ETD5; hsa:25936; Q5SY75; Q96IY1; Q9H2M5; Q9NRN8; Q9Y415"	""	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"6"	"0"	"43.1"	"36.1"	"60.5"	"46.5"	"43.1"	"42.8"	"80.3"	"128.4"	"138.9"	"344.5"	"474.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P000"	"COMM domain-containing protein 9 OS=Homo sapiens OX=9606 GN=COMMD9 PE=1 SV=2"	"0.000"	""	"11"	"2"	"3"	"2"	"198"	"21.8"	"5.88"	"239.28"	"6.58"	"1"	"2"	"transport;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;nucleus;other cell component"	""	"Pf07258"	"29099"	"ENSG00000110442"	"COMMD9"	"E9PAN2; hsa:29099; Q96FI2; Q9H0R0; Q9P000"	""	"Neddylation; Neutrophil degranulation"	"2"	"0"	"28.1"	"16.4"	"20.3"	"16.7"	"24.7"	"22.4"	"21.9"	"53.1"	"69.6"	"224.2"	"435.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBD5"	"Origin recognition complex subunit 3 OS=Homo sapiens OX=9606 GN=ORC3 PE=1 SV=1"	"0.000"	""	"3"	"2"	"4"	"2"	"711"	"82.2"	"7.61"	"664.85"	"6.58"	"2"	"2"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf07034, Pf18137, Pf19675"	"23595"	"ENSG00000135336"	"ORC3"	"A2A2T5; B4E025; hsa:23595; Q13565; Q53GY6; Q5T159; Q6IUY7; Q86TN5; Q9UBD5; Q9UG44; Q9UNT6"	"Cell cycle; G1 to S cell cycle control; DNA replication"	"Orc1 removal from chromatin; Activation of the pre-replicative complex; Assembly of the ORC complex at the origin of replication; Activation of ATR in response to replication stress; E2F-enabled inhibition of pre-replication complex formation; CDC6 association with the ORC:origin complex"	"10"	"0"	"39.7"	"26.1"	"35.0"	"31.7"	"32.1"	"32.3"	"44.5"	"100.1"	"115.3"	"254.0"	"310.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95425"	"Supervillin OS=Homo sapiens OX=9606 GN=SVIL PE=1 SV=2"	"0.000"	""	"1"	"2"	"3"	"2"	"2214"	"247.6"	"6.98"	"388.42"	"6.58"	"1"	"2"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00626, Pf02209"	"6840"	"ENSG00000197321"	"SVIL"	"D3DRW9; hsa:6840; M1J557; O60611; O60612; O95425; Q5VZK5; Q5VZK6; Q9H1R7"	""	""	"0"	"0"	"19.3"	"22.8"	"17.0"	"23.4"	"16.2"	"22.5"	"29.8"	"35.7"	"59.2"	"140.9"	"170.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00170"	"AH receptor-interacting protein OS=Homo sapiens OX=9606 GN=AIP PE=1 SV=2"	"0.000"	""	"5"	"1"	"2"	"1"	"330"	"37.6"	"6.29"	"578.44"	"6.56"	"1"	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"48.2"	"44.7"	"53.5"	"45.2"	"53.5"	"51.4"	"61.0"	"93.6"	"83.3"	"136.0"	"172.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15370"	"Elongin-B OS=Homo sapiens OX=9606 GN=ELOB PE=1 SV=1"	"0.000"	""	"14"	"2"	"4"	"2"	"118"	"13.1"	"4.88"	"727.54"	"6.55"	"2"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00240"	"6923"	"ENSG00000103363"	"ELOB"	"B7WPD3; hsa:6923; Q15370"	"Dual hijack model of Vif in HIV infection; Type 2 papillary renal cell carcinoma; Hijack of ubiquitination by SARS-CoV-2; Modulators of TCR signaling and T cell activation"	"Regulation of expression of SLITs and ROBOs; Antigen processing: Ubiquitination & Proteasome degradation; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Vif-mediated degradation of APOBEC3G; Neddylation; Inactivation of CSF3 (G-CSF) signaling; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes"	"21"	"0"	"186.1"	"150.1"	"208.9"	"179.5"	"170.4"	"176.5"	"227.1"	"470.2"	"421.9"	"982.0"	"1295.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q56P03"	"E2F-associated phosphoprotein OS=Homo sapiens OX=9606 GN=EAPP PE=1 SV=4"	"0.000"	""	"4"	"1"	"4"	"1"	"285"	"32.7"	"5.12"	"963.81"	"6.55"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	""	"Pf10238"	"55837"	"ENSG00000129518"	"EAPP"	"hsa:55837; Q56P03; Q9BVF4; Q9NWV5; Q9NZ86"	""	""	"0"	"0"	"43.7"	"34.6"	"40.0"	"40.8"	"45.4"	"38.8"	"47.7"	"72.7"	"72.7"	"152.5"	"236.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UHD1"	"Cysteine and histidine-rich domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHORDC1 PE=1 SV=2"	"0.000"	""	"7"	"2"	"3"	"2"	"332"	"37.5"	"7.87"	"249.13"	"6.54"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	""	"other molecular function"	"Pf04968, Pf04969"	"26973"	"ENSG00000110172; ENSG00000285023"	"CHORDC1"	"B2R6P8; hsa:26973; Q6IN49; Q8WVL9; Q9H3D6; Q9UHD1"	""	""	"0"	"0"	"35.3"	"37.0"	"47.1"	"45.9"	"38.0"	"38.5"	"46.5"	"140.1"	"110.9"	"874.2"	"2774.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y223"	"Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase OS=Homo sapiens OX=9606 GN=GNE PE=1 SV=1"	"0.000"	""	"3"	"2"	"4"	"2"	"722"	"79.2"	"6.80"	"440.84"	"6.54"	"1"	"2"	"cell adhesion;other metabolic processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00480, Pf02350"	"10020"	"ENSG00000159921"	"GNE"	"A6PZH2; A6PZH3; A7UNU7; B2R6E1; B7Z372; B7Z428; D3DRP7; F5H499; H0YFA7; hsa:10020; Q0VA94; Q9Y223"	""	"Sialic acid metabolism; Defective GNE causes sialuria, NK and IBM2"	"2"	"0"	"51.6"	"36.2"	"41.5"	"42.4"	"48.7"	"47.3"	"60.6"	"162.8"	"149.3"	"561.1"	"957.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UK45"	"U6 snRNA-associated Sm-like protein LSm7 OS=Homo sapiens OX=9606 GN=LSM7 PE=1 SV=1"	"0.000"	""	"40"	"3"	"4"	"3"	"103"	"11.6"	"5.27"	"559.39"	"6.54"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01423"	"51690"	"ENSG00000130332"	"LSM7"	"hsa:51690; Q9UK45"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA decay by 5' to 3' exoribonuclease"	"3"	"0"	"238.8"	"193.6"	"260.7"	"236.6"	"218.9"	"238.6"	"309.4"	"483.7"	"427.8"	"1201.0"	"2593.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H4M9"	"EH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=EHD1 PE=1 SV=2"	"0.000"	""	"5"	"2"	"4"	"2"	"534"	"60.6"	"6.83"	"680.17"	"6.53"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00350, Pf12763, Pf16880, Pf18150"	"10938"	"ENSG00000110047"	"EHD1"	"hsa:10938; O14611; Q2M3Q4; Q9H4M9; Q9UNR3"	"Insulin signaling"	"Factors involved in megakaryocyte development and platelet production"	"2"	"0"	"37.9"	"26.9"	"47.8"	"42.1"	"38.3"	"40.5"	"50.3"	"98.0"	"101.3"	"228.3"	"279.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P20962"	"Parathymosin OS=Homo sapiens OX=9606 GN=PTMS PE=1 SV=2"	"0.000"	""	"11"	"1"	"4"	"1"	"102"	"11.5"	"4.16"	"752.31"	"6.51"	"1"	"1"	"DNA metabolism;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf03247"	"5763"	"ENSG00000159335"	"PTMS"	"hsa:5763; P20962"	"IL-18 signaling pathway"	""	"1"	"0"	"422.5"	"329.4"	"327.5"	"343.7"	"344.7"	"354.5"	"400.5"	"528.7"	"531.9"	"674.2"	"662.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P1N9"	"Putative deoxyribonuclease TATDN1 OS=Homo sapiens OX=9606 GN=TATDN1 PE=1 SV=2"	"0.000"	""	"5"	"2"	"4"	"2"	"297"	"33.6"	"6.96"	"693.97"	"6.49"	"2"	"2"	"DNA metabolism"	"nucleus"	"other molecular function"	"Pf01026"	"83940"	"ENSG00000147687"	"TATDN1"	"B2R5J0; hsa:83940; Q6P1N9; Q8TD02; Q9BY40"	""	""	"0"	"0"	"12.0"	"10.4"	"18.3"	"14.6"	"12.3"	"11.6"	"22.5"	"34.7"	"57.7"	"121.1"	"183.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N9N5"	"Protein BANP OS=Homo sapiens OX=9606 GN=BANP PE=1 SV=3"	"0.000"	""	"8"	"3"	"4"	"3"	"519"	"56.5"	"5.49"	"638.92"	"6.48"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf10523"	"54971"	"ENSG00000172530"	"BANP"	"A8MU25; A8MX25; B2RCF7; B4DNJ9; F5GZM0; hsa:54971; Q8N9N5; Q96GJ7; Q9NWY1"	""	"Regulation of TP53 Activity through Association with Co-factors"	"1"	"0"	"286.8"	"198.1"	"209.8"	"222.1"	"195.5"	"224.2"	"286.5"	"393.4"	"450.0"	"730.1"	"816.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BQ04"	"RNA-binding protein 4B OS=Homo sapiens OX=9606 GN=RBM4B PE=1 SV=1"	"0.000"	""	"10"	"2"	"2"	"2"	"359"	"40.1"	"6.74"	"256.95"	"6.48"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00076, Pf00098"	"83759"	"ENSG00000173914"	"RBM4B"	"B3KT83; hsa:83759; Q9BQ04"	""	""	"0"	"0"	"184.8"	"139.4"	"176.7"	"173.0"	"160.2"	"149.3"	"217.0"	"316.7"	"273.9"	"631.7"	"888.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86TJ2"	"Transcriptional adapter 2-beta OS=Homo sapiens OX=9606 GN=TADA2B PE=1 SV=2"	"0.000"	""	"5"	"2"	"4"	"2"	"420"	"48.4"	"7.83"	"740.83"	"6.48"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00249"	"93624"	"ENSG00000173011"	"TADA2B"	"A0AUJ8; A4QMR7; B3KSN0; B3KU86; hsa:93624; Q6MZG9; Q86TJ2"	""	"HATs acetylate histones; Ub-specific processing proteases"	"2"	"0"	"29.4"	"22.7"	"18.1"	"20.3"	"20.3"	"21.3"	"32.5"	"76.0"	"72.5"	"126.7"	"143.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96G46"	"tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like OS=Homo sapiens OX=9606 GN=DUS3L PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"650"	"72.5"	"8.05"	"601.60"	"6.48"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	""	"other molecular function"	"Pf01207, Pf18044"	"56931"	"ENSG00000141994"	"DUS3L"	"hsa:56931; Q96G46; Q96HM5; Q9BSU4; Q9H877; Q9NPR1"	""	""	"0"	"0"	"49.3"	"38.4"	"46.1"	"42.7"	"48.7"	"41.7"	"54.1"	"74.1"	"67.5"	"113.6"	"137.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14155"	"Rho guanine nucleotide exchange factor 7 OS=Homo sapiens OX=9606 GN=ARHGEF7 PE=1 SV=2"	"0.000"	""	"4"	"2"	"3"	"2"	"803"	"90.0"	"7.09"	"1004.92"	"6.47"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00169, Pf00307, Pf00621, Pf07653, Pf16614, Pf16615"	"8874"	"ENSG00000102606"	"ARHGEF7"	"B1ALK6; B1ALK8; hsa:8874; Q14155; Q3LIA4; Q5W9H0; Q6P9G3; Q6PII2; Q86W63; Q8N3M1"	"Integrin-mediated cell adhesion; CAMKK2 pathway; Regulation of actin cytoskeleton"	"RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; NRAGE signals death through JNK; G alpha (12/13) signalling events; RHOJ GTPase cycle; Ephrin signaling; RHOQ GTPase cycle; RHOV GTPase cycle; RHOU GTPase cycle; EGFR downregulation"	"14"	"0"	"161.0"	"144.6"	"149.0"	"154.7"	"142.6"	"138.7"	"183.1"	"383.2"	"384.2"	"875.3"	"1202.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6PFW1"	"Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 OS=Homo sapiens OX=9606 GN=PPIP5K1 PE=1 SV=1"	"0.000"	""	"2"	"2"	"4"	"1"	"1433"	"159.4"	"5.40"	"818.16"	"6.46"	"2"	"2"	"other metabolic processes"	"plasma membrane;other membranes;cytosol"	"kinase activity;other molecular function"	"Pf00328, Pf18086"	"9677"	"ENSG00000168781"	"PPIP5K1"	"hsa:9677; O15082; Q5HYF8; Q6PFW1; Q7Z3A7; Q86TE7; Q86UV3; Q86UV4; Q86XW8; Q8IZN0"	""	"Synthesis of pyrophosphates in the cytosol"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q13416"	"Origin recognition complex subunit 2 OS=Homo sapiens OX=9606 GN=ORC2 PE=1 SV=2"	""	""	"4"	"1"	"1"	"1"	"577"	"65.9"	"6.51"	""	"6.45"	""	"1"	"DNA metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity"	"Pf04084"	"4999"	"ENSG00000115942"	"ORC2"	"hsa:4999; Q13204; Q13416; Q53TX5"	"Cell cycle; G1 to S cell cycle control; DNA replication"	"Orc1 removal from chromatin; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; E2F-enabled inhibition of pre-replication complex formation; Assembly of the ORC complex at the origin of replication; CDC6 association with the ORC:origin complex"	"10"	"0"	"15.8"	"16.7"	"16.4"	"21.3"	"14.2"	"14.2"	"19.5"	"47.1"	"40.0"	"102.9"	"113.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P27448"	"MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens OX=9606 GN=MARK3 PE=1 SV=5"	"0.000"	""	"4"	"2"	"4"	"2"	"753"	"84.4"	"9.57"	"947.05"	"6.45"	"2"	"2"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"cytoskeletal activity;kinase activity;other molecular function"	"Pf00069, Pf00627, Pf02149"	"4140"	"ENSG00000075413"	"MARK3"	"A0A0A0MQR8; A0A0A0MST9; A0A0A0MT23; hsa:4140; O60219; P27448; Q86TT8; Q8TB41; Q8WX83; Q96RG1; Q9UMY9; Q9UN34"	"Complement system in neuronal development and plasticity"	"Signaling by BRAF and RAF1 fusions; RAF activation; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Negative regulation of MAPK pathway; Signaling by high-kinase activity BRAF mutants"	"10"	"0"	"37.3"	"24.6"	"32.5"	"30.6"	"29.2"	"32.1"	"40.8"	"96.2"	"104.7"	"205.8"	"237.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23786"	"Carnitine O-palmitoyltransferase 2, mitochondrial OS=Homo sapiens OX=9606 GN=CPT2 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"658"	"73.7"	"8.18"	"686.26"	"6.43"	"2"	"2"	"other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf00755"	"1376"	"ENSG00000157184"	"CPT2"	"B2R6S0; hsa:1376; P23786; Q5SW68; Q9BQ26"	"Fatty acid beta-oxidation; PPAR-alpha pathway; Nuclear receptors meta-pathway; Mitochondrial long chain fatty acid beta-oxidation; PPAR signaling pathway; Thermogenesis; Mitochondrial fatty acid oxidation disorders"	"PPARA activates gene expression; Carnitine metabolism"	"9"	"0"	"14.0"	"11.2"	"18.4"	"14.5"	"18.0"	"14.4"	"24.7"	"39.7"	"32.5"	"69.6"	"103.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P36551"	"Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3"	"0.000"	""	"4"	"1"	"2"	"1"	"454"	"50.1"	"8.25"	"716.98"	"6.43"	"1"	"1"	"other metabolic processes;other biological processes"	"other membranes;cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf01218"	"1371"	"ENSG00000080819"	"CPOX"	"A8K275; B4DSD5; hsa:1371; P36551; Q14060; Q53F08; Q8IZ45; Q96AF3"	"Hemesynthesis defects and porphyrias; Heme biosynthesis"	"Heme biosynthesis"	"3"	"0"	"6.8"	"7.6"	"12.7"	"6.7"	"6.4"	"9.2"	"11.1"	"24.2"	"26.2"	"207.0"	"639.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13596"	"Sorting nexin-1 OS=Homo sapiens OX=9606 GN=SNX1 PE=1 SV=3"	"0.000"	""	"4"	"2"	"3"	"1"	"522"	"59.0"	"5.15"	"295.08"	"6.43"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00787, Pf03700, Pf09325"	"6642"	"ENSG00000028528"	"SNX1"	"A6NM19; A8K6T7; H0Y2M5; hsa:6642; O60750; O60751; Q13596; Q6ZRJ8"	""	""	"0"	"0"	"5.5"	"4.8"	"3.5"	"3.7"	"4.8"	"6.2"	"5.4"	"24.8"	"28.9"	"115.1"	"278.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P45877"	"Peptidyl-prolyl cis-trans isomerase C OS=Homo sapiens OX=9606 GN=PPIC PE=1 SV=1"	"0.000"	""	"11"	"2"	"3"	"2"	"212"	"22.7"	"8.40"	"364.19"	"6.42"	"1"	"2"	"protein metabolism;other metabolic processes"	"other cell component"	"other molecular function"	"Pf00160"	"5480"	"ENSG00000168938"	"PPIC"	"A4LBB5; hsa:5480; P45877"	""	""	"0"	"0"	"40.0"	"30.7"	"53.0"	"51.1"	"43.3"	"49.6"	"66.7"	"125.8"	"158.3"	"384.2"	"493.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51452"	"Dual specificity protein phosphatase 3 OS=Homo sapiens OX=9606 GN=DUSP3 PE=1 SV=1"	"0.000"	""	"13"	"2"	"4"	"2"	"185"	"20.5"	"7.80"	"667.41"	"6.40"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00782"	"1845"	"ENSG00000108861"	"DUSP3"	"D3DX45; hsa:1845; P51452; Q5U0J1; Q8IYJ9"	"MAPK signaling pathway; Fragile X syndrome"	"ERKs are inactivated"	"3"	"0"	"32.9"	"25.0"	"28.6"	"29.1"	"27.9"	"26.7"	"35.5"	"64.3"	"60.4"	"172.5"	"214.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H2H8"	"Peptidyl-prolyl cis-trans isomerase-like 3 OS=Homo sapiens OX=9606 GN=PPIL3 PE=1 SV=1"	"0.000"	""	"16"	"3"	"5"	"3"	"161"	"18.1"	"6.79"	"861.15"	"6.40"	"3"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00160"	"53938"	"ENSG00000240344"	"PPIL3"	"hsa:53938; Q86WF9; Q96IA9; Q9BXZ1; Q9H2H8"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"329.0"	"254.5"	"284.6"	"299.5"	"265.0"	"312.7"	"373.8"	"758.7"	"723.0"	"1580.7"	"1809.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EY7"	"Pentatricopeptide repeat domain-containing protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=PTCD3 PE=1 SV=3"	"0.000"	""	"4"	"2"	"4"	"2"	"689"	"78.5"	"6.42"	"717.57"	"6.40"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;translational apparatus;nucleus"	"translation activity;nucleic acid binding activity"	"Pf13041, Pf13812"	"55037"	"ENSG00000132300"	"PTCD3"	"A6NHD2; D6W5M1; hsa:55037; Q597H0; Q658Y9; Q96EY7; Q9BUZ8; Q9NWL0"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"19.9"	"22.1"	"25.3"	"28.1"	"23.6"	"27.4"	"35.9"	"54.6"	"49.8"	"89.1"	"135.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q66LE6"	"Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform OS=Homo sapiens OX=9606 GN=PPP2R2D PE=1 SV=1"	"0.000"	""	"6"	"2"	"4"	"2"	"453"	"52.0"	"6.39"	"693.22"	"6.39"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity"	""	"55844"	"ENSG00000175470"	"PPP2R2D"	"A8KAK0; hsa:55844; Q5SQJ2; Q66LE6; Q9P1Y7"	"Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway"	"MASTL Facilitates Mitotic Progression"	"3"	"0"	"49.0"	"32.3"	"59.1"	"44.3"	"40.5"	"52.4"	"65.0"	"116.8"	"118.1"	"346.2"	"688.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P38117"	"Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3"	"0.000"	""	"9"	"2"	"3"	"2"	"255"	"27.8"	"8.10"	"476.93"	"6.39"	"1"	"2"	"other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf01012"	"2109"	"ENSG00000105379"	"ETFB"	"A8K766; B3KNY2; hsa:2109; P38117; Q6IBH7; Q71RF6; Q9Y3S7"	""	"Respiratory electron transport; Protein methylation"	"2"	"0"	"123.0"	"65.1"	"121.8"	"96.3"	"108.5"	"108.8"	"137.5"	"265.8"	"210.9"	"478.8"	"826.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86WJ1"	"Chromodomain-helicase-DNA-binding protein 1-like OS=Homo sapiens OX=9606 GN=CHD1L PE=1 SV=3"	"0.000"	""	"3"	"2"	"3"	"2"	"897"	"100.9"	"6.90"	"307.98"	"6.38"	"1"	"2"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00176, Pf00271"	"9557"	"ENSG00000131778"	"CHD1L"	"A5YM64; B4DDE1; B5MDZ7; hsa:9557; Q53EZ3; Q5VXX7; Q6DD94; Q6PK83; Q86WJ1; Q86XH3; Q96HF7; Q96SP3; Q9BVJ1; Q9NVV8"	"1q21.1 copy number variation syndrome; Nucleotide excision repair in xeroderma pigmentosum"	"Formation of Incision Complex in GG-NER; Dual Incision in GG-NER"	"4"	"0"	"83.6"	"69.9"	"87.4"	"81.7"	"79.9"	"90.3"	"105.6"	"167.2"	"166.8"	"357.1"	"414.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62487"	"DNA-directed RNA polymerase II subunit RPB7 OS=Homo sapiens OX=9606 GN=POLR2G PE=1 SV=1"	"0.000"	""	"19"	"2"	"3"	"2"	"172"	"19.3"	"5.54"	"303.05"	"6.38"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00575, Pf03876"	"5436"	"ENSG00000168002"	"POLR2G"	"B2R5C0; hsa:5436; P52433; P62487; Q2M1Z4"	"Pyrimidine metabolism; Eukaryotic transcription initiation"	"Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; mRNA Splicing - Major Pathway; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"43"	"0"	"12.8"	"11.8"	"10.5"	"8.8"	"6.8"	"12.4"	"17.3"	"24.6"	"20.4"	"42.1"	"62.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BYD1"	"39S ribosomal protein L13, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL13 PE=1 SV=1"	"0.000"	""	"8"	"1"	"2"	"1"	"178"	"20.7"	"9.16"	"620.62"	"6.38"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00572"	"28998"	"ENSG00000172172"	"MRPL13"	"B2R4R8; hsa:28998; Q9BYD1; Q9UI04"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"23.4"	"22.4"	"23.2"	"31.8"	"34.4"	"31.9"	"31.7"	"51.0"	"49.7"	"107.9"	"159.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L266"	"Isoaspartyl peptidase/L-asparaginase OS=Homo sapiens OX=9606 GN=ASRGL1 PE=1 SV=2"	"0.000"	""	"8"	"2"	"3"	"2"	"308"	"32.0"	"6.24"	"269.99"	"6.38"	"1"	"2"	"protein metabolism;other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf01112"	"80150"	"ENSG00000162174"	"ASRGL1"	"B2R7Q0; hsa:80150; Q567Q4; Q6P1P0; Q7L266; Q8NI34; Q9H6F7"	""	"Phenylalanine metabolism"	"1"	"0"	"57.9"	"23.2"	"70.6"	"70.7"	"61.1"	"63.7"	"85.5"	"191.1"	"188.0"	"430.9"	"583.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HB21"	"Pleckstrin homology domain-containing family A member 1 OS=Homo sapiens OX=9606 GN=PLEKHA1 PE=1 SV=2"	"0.000"	""	"5"	"2"	"4"	"2"	"404"	"45.5"	"8.56"	"717.79"	"6.37"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00169"	"59338"	"ENSG00000107679"	"PLEKHA1"	"B3KQ55; D3DRE2; hsa:59338; Q9BVK0; Q9HB21"	""	"Synthesis of PIPs at the plasma membrane"	"1"	"0"	"44.8"	"39.3"	"44.0"	"40.3"	"59.1"	"88.6"	"148.7"	"340.8"	"335.2"	"524.5"	"426.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WV22"	"Non-structural maintenance of chromosomes element 1 homolog OS=Homo sapiens OX=9606 GN=NSMCE1 PE=1 SV=5"	"0.001"	""	"12"	"2"	"3"	"2"	"266"	"30.8"	"7.47"	"231.57"	"6.36"	"1"	"2"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf07574, Pf08746"	"197370"	"ENSG00000169189"	"NSMCE1"	"D3DWF6; hsa:197370; Q8WV22; Q9P045; Q9P049"	""	"SUMOylation of DNA damage response and repair proteins"	"1"	"0"	"118.4"	"107.1"	"126.2"	"111.1"	"117.0"	"120.6"	"151.2"	"239.7"	"222.0"	"511.0"	"661.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BZI7"	"Regulator of nonsense transcripts 3B OS=Homo sapiens OX=9606 GN=UPF3B PE=1 SV=1"	"0.000"	""	"7"	"3"	"5"	"3"	"483"	"57.7"	"9.48"	"1320.74"	"6.34"	"3"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity"	"Pf03467"	"65109"	"ENSG00000125351"	"UPF3B"	"D3DWI3; D3DWI4; hsa:65109; Q0VAK8; Q9BZI7; Q9H1J0"	""	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing"	"6"	"0"	"457.6"	"416.5"	"469.0"	"462.0"	"448.5"	"465.8"	"622.5"	"590.3"	"555.8"	"711.6"	"867.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BRP1"	"Programmed cell death protein 2-like OS=Homo sapiens OX=9606 GN=PDCD2L PE=1 SV=1"	"0.000"	""	"9"	"2"	"3"	"2"	"358"	"39.4"	"4.86"	"729.33"	"6.34"	"1"	"2"	"cell cycle OR cell proliferation;other biological processes"	"other cell component"	""	"Pf04194"	"84306"	"ENSG00000126249"	"PDCD2L"	"hsa:84306; Q9BRP1"	""	""	"0"	"0"	"167.9"	"115.0"	"162.7"	"172.1"	"156.8"	"121.1"	"192.8"	"403.8"	"388.1"	"614.9"	"557.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62195"	"26S proteasome regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMC5 PE=1 SV=1"	"0.000"	""	"6"	"2"	"4"	"2"	"406"	"45.6"	"7.55"	"615.08"	"6.33"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00004, Pf16450, Pf17862"	"5705"	"ENSG00000087191"	"PSMC5"	"A8K3Z3; A8K763; hsa:5705; O35051; O43208; P47210; P52915; P52916; P62195"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Pregnane X receptor pathway; Nuclear receptors meta-pathway; Alzheimer's disease"	"ABC-family proteins mediated transport; Regulation of expression of SLITs and ROBOs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Interleukin-1 signaling; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"65"	"0"	"8.3"	"4.8"	"7.8"	"9.9"	"5.3"	"7.1"	"14.8"	"29.4"	"26.7"	"67.2"	"154.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42677"	"40S ribosomal protein S27 OS=Homo sapiens OX=9606 GN=RPS27 PE=1 SV=3"	"0.000"	""	"25"	"2"	"4"	"2"	"84"	"9.5"	"9.45"	"574.56"	"6.32"	"2"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01667"	"6232"	"ENSG00000177954"	"RPS27"	"hsa:6232; P42677; Q5T4L6"	"Cytoplasmic ribosomal proteins"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"25"	"0"	"175.5"	"172.5"	"190.2"	"181.0"	"167.1"	"157.6"	"228.6"	"327.3"	"314.1"	"611.6"	"822.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P1K2"	"Polyamine-modulated factor 1 OS=Homo sapiens OX=9606 GN=PMF1 PE=1 SV=2"	"0.000"	""	"11"	"2"	"4"	"2"	"205"	"23.3"	"5.49"	"591.77"	"6.32"	"2"	"2"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf03980"	"100527963; 11243"	"ENSG00000160783"	"PMF1"	"A8K0C5; hsa:100527963; hsa:11243; Q5TCJ8; Q5TCJ9; Q5TCK0; Q5TCK1; Q5TCK3; Q69YZ9; Q6P1K2; Q6PHR4; Q6ZVE6; Q86VJ6; Q8N4T6; Q9UBQ3"	""	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"6"	"0"	"59.9"	"38.4"	"57.1"	"56.8"	"53.2"	"61.7"	"70.5"	"206.1"	"232.0"	"688.8"	"949.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NAV1"	"Pre-mRNA-splicing factor 38A OS=Homo sapiens OX=9606 GN=PRPF38A PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"312"	"37.5"	"9.96"	"643.20"	"6.31"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf03371, Pf12871"	"84950"	"ENSG00000134748"	"PRPF38A"	"hsa:84950; Q8NAV1; Q96JW1; Q9BVZ8"	"MECP2 and associated Rett syndrome"	"mRNA Splicing - Major Pathway"	"2"	"0"	"54.5"	"39.7"	"51.7"	"48.6"	"41.6"	"42.0"	"57.1"	"95.5"	"90.4"	"237.4"	"300.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6PJT7"	"Zinc finger CCCH domain-containing protein 14 OS=Homo sapiens OX=9606 GN=ZC3H14 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"736"	"82.8"	"7.31"	"574.28"	"6.31"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf14608"	"79882"	"ENSG00000100722"	"ZC3H14"	"A8MY46; B4DXU8; B4DZW7; B4E2H4; G3V5R4; hsa:79882; Q6MZU4; Q6PJ32; Q6PJT7; Q6PUI6; Q6PUI8; Q86TQ5; Q86TW0; Q86TW1; Q8NCT6; Q8NCZ3; Q8TDE2; Q9HAC9; Q9Y5A0"	""	""	"0"	"0"	"16.5"	"21.3"	"11.3"	"12.0"	"17.9"	"17.2"	"15.0"	"25.0"	"19.6"	"36.6"	"56.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86U44"	"N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2"	"0.000"	""	"9"	"3"	"4"	"3"	"580"	"64.4"	"6.42"	"1620.31"	"6.29"	"3"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05063"	"56339"	"ENSG00000165819"	"METTL3"	"hsa:56339; O14736; Q86U44; Q86V05; Q9HB32"	"mRNA processing"	"Processing of Capped Intron-Containing Pre-mRNA"	"2"	"0"	"125.1"	"89.9"	"110.6"	"137.3"	"111.0"	"114.2"	"116.7"	"223.1"	"222.0"	"544.8"	"619.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P00492"	"Hypoxanthine-guanine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=HPRT1 PE=1 SV=2"	"0.000"	""	"13"	"2"	"4"	"2"	"218"	"24.6"	"6.68"	"846.26"	"6.28"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;developmental processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00156"	"3251"	"ENSG00000165704"	"HPRT1"	"A6NHF0; B2R8M9; hsa:3251; P00492"	"Mesodermal commitment pathway"	"Azathioprine ADME; Purine salvage; Defective HPRT1 disrupts guanine and hypoxanthine salvage"	"4"	"0"	"51.4"	"42.0"	"63.7"	"47.7"	"38.7"	"36.0"	"55.1"	"77.5"	"78.7"	"148.9"	"203.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75152"	"Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3"	"0.000"	""	"5"	"4"	"6"	"4"	"810"	"89.1"	"8.37"	"1621.58"	"6.28"	"4"	"2"	"other metabolic processes;transport"	"nucleus"	"other molecular function"	"Pf15663"	"9877"	"ENSG00000058673"	"ZC3H11A"	"hsa:9877; O75152; Q6AHY4; Q6AHY9; Q6AW79; Q6AWA1; Q6PJK4; Q86XZ7"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"3"	"0"	"279.3"	"243.0"	"280.0"	"265.7"	"250.9"	"247.7"	"327.6"	"305.2"	"313.4"	"403.3"	"600.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z392"	"Trafficking protein particle complex subunit 11 OS=Homo sapiens OX=9606 GN=TRAPPC11 PE=1 SV=2"	"0.000"	""	"4"	"3"	"4"	"3"	"1133"	"128.8"	"7.14"	"789.36"	"6.27"	"2"	"2"	"cell organization and biogenesis;transport;other biological processes"	"cytosol;ER/Golgi;other cell component"	""	"Pf11817, Pf12742"	"60684"	"ENSG00000168538"	"TRAPPC11"	"A4QPB8; B2RCD6; hsa:60684; Q5U5I7; Q6FI73; Q7Z392; Q86T25; Q9H0L1; Q9H5K9; Q9H8Q1; Q9H9I7"	"Genes related to primary cilium development (based on CRISPR)"	"RAB GEFs exchange GTP for GDP on RABs"	"2"	"0"	"8.7"	"12.7"	"16.3"	"21.4"	"13.0"	"10.5"	"27.4"	"88.7"	"78.2"	"172.8"	"309.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IXQ4"	"GPALPP motifs-containing protein 1 OS=Homo sapiens OX=9606 GN=GPALPP1 PE=1 SV=1"	"0.000"	""	"6"	"2"	"4"	"2"	"340"	"38.1"	"5.41"	"600.50"	"6.25"	"2"	"2"	""	""	""	"Pf12572"	"55425"	"ENSG00000133114"	"GPALPP1"	"A8K8X8; hsa:55425; Q05BX8; Q05D87; Q5T3Z3; Q5T3Z5; Q8IXQ4; Q9C0F9; Q9H2R0; Q9P0W6"	""	""	"0"	"0"	"190.6"	"164.4"	"202.5"	"178.6"	"223.3"	"213.4"	"253.3"	"279.4"	"290.5"	"402.6"	"472.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2X3"	"Nucleolar protein 58 OS=Homo sapiens OX=9606 GN=NOP58 PE=1 SV=1"	"0.000"	""	"7"	"3"	"5"	"3"	"529"	"59.5"	"8.92"	"1114.92"	"6.24"	"3"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01798, Pf08156"	"51602"	"ENSG00000055044"	"NOP58"	"hsa:51602; Q53SA4; Q6PK08; Q9P036; Q9UFN3; Q9Y2X3"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; SUMOylation of RNA binding proteins; rRNA modification in the nucleus and cytosol"	"3"	"0"	"165.4"	"115.4"	"166.1"	"151.2"	"154.0"	"169.1"	"198.4"	"319.5"	"333.5"	"689.9"	"985.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BX40"	"Protein LSM14 homolog B OS=Homo sapiens OX=9606 GN=LSM14B PE=1 SV=1"	"0.000"	""	"8"	"3"	"3"	"2"	"385"	"42.0"	"9.69"	"252.82"	"6.23"	"1"	"2"	"other biological processes"	"other cell component"	"nucleic acid binding activity"	"Pf09532, Pf12701"	"149986"	"ENSG00000149657"	"LSM14B"	"hsa:149986; Q6PFW8; Q96LH8; Q9BX40"	""	""	"0"	"0"	"58.3"	"44.6"	"58.4"	"45.6"	"48.8"	"50.9"	"62.3"	"78.3"	"86.7"	"162.4"	"193.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96LB3"	"Intraflagellar transport protein 74 homolog OS=Homo sapiens OX=9606 GN=IFT74 PE=1 SV=1"	"0.000"	""	"6"	"2"	"3"	"2"	"600"	"69.2"	"6.00"	"397.74"	"6.23"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	""	"80173"	"ENSG00000096872"	"IFT74"	"hsa:80173; Q3B789; Q5VY34; Q6PGQ8; Q96LB3; Q9H643; Q9H8G7"	"Ciliary landscape; Genes related to primary cilium development (based on CRISPR); Alstrom syndrome; Bardet-Biedl syndrome"	"Intraflagellar transport"	"5"	"0"	"203.3"	"54.4"	"288.0"	"206.9"	"196.9"	"210.4"	"255.8"	"327.4"	"341.9"	"579.8"	"573.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51649"	"Succinate-semialdehyde dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH5A1 PE=1 SV=2"	"0.000"	""	"8"	"2"	"3"	"2"	"535"	"57.2"	"8.28"	"290.07"	"6.23"	"1"	"2"	"other metabolic processes;developmental processes"	"mitochondrion"	"other molecular function"	"Pf00171"	"7915"	"ENSG00000112294"	"ALDH5A1"	"B2RD26; G5E949; hsa:7915; P51649; Q546H9; Q8N3W6"	"Fragile X syndrome"	"Degradation of GABA"	"2"	"0"	"7.0"	"5.4"	"6.6"	"3.7"	"6.6"	"4.2"	"7.8"	"19.9"	"20.1"	"60.1"	"103.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75970"	"Multiple PDZ domain protein OS=Homo sapiens OX=9606 GN=MPDZ PE=1 SV=2"	"0.000"	""	"1"	"2"	"3"	"2"	"2070"	"221.5"	"5.06"	"250.25"	"6.22"	"1"	"2"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;other cell component"	""	"Pf00595, Pf09045, Pf16667"	"8777"	"ENSG00000107186"	"MPDZ"	"A6NLC2; B2RTS3; B7ZMI4; hsa:8777; O43798; O75970; Q4LE30; Q5CZ80; Q5JTX3; Q5JTX6; Q5JTX7; Q5JUC3; Q5JUC4; Q5VZ62; Q8N790"	""	""	"0"	"0"	"140.7"	"100.9"	"132.7"	"121.7"	"107.2"	"120.5"	"154.1"	"340.9"	"339.8"	"861.8"	"1251.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75962"	"Triple functional domain protein OS=Homo sapiens OX=9606 GN=TRIO PE=1 SV=2"	"0.000"	""	"1"	"2"	"3"	"2"	"3097"	"346.7"	"6.37"	"301.95"	"6.22"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00018, Pf00069, Pf00169, Pf00435, Pf00621, Pf00650, Pf07679, Pf16609"	"7204"	"ENSG00000038382"	"TRIO"	"D3DTD1; hsa:7204; O75962; Q13458; Q59EQ7; Q6PJC9; Q6ZN05; Q8IWK8"	"Microtubule cytoskeleton regulation; Neural crest cell migration during development; Neural crest cell migration in cancer"	"RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; NRAGE signals death through JNK; G alpha (12/13) signalling events; RHOG GTPase cycle; G alpha (q) signalling events; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOJ GTPase cycle; DCC mediated attractive signaling"	"14"	"0"	"19.6"	"14.0"	"23.6"	"19.1"	"15.5"	"24.8"	"30.7"	"75.6"	"69.6"	"133.1"	"167.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EH3"	"Mitochondrial assembly of ribosomal large subunit protein 1 OS=Homo sapiens OX=9606 GN=MALSU1 PE=1 SV=1"	"0.000"	""	"8"	"2"	"3"	"2"	"234"	"26.2"	"5.49"	"404.30"	"6.22"	"1"	"2"	"other biological processes"	"cytosol;mitochondrion"	"translation activity"	"Pf02410"	"115416"	"ENSG00000156928"	"MALSU1"	"A4D154; hsa:115416; Q96EH3"	""	""	"0"	"0"	"59.2"	"50.2"	"59.1"	"56.4"	"55.8"	"54.0"	"77.3"	"220.2"	"211.9"	"565.8"	"933.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15212"	"Prefoldin subunit 6 OS=Homo sapiens OX=9606 GN=PFDN6 PE=1 SV=1"	"0.000"	""	"16"	"2"	"3"	"2"	"129"	"14.6"	"8.88"	"382.70"	"6.21"	"1"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"other cell component"	"other molecular function"	"Pf01920"	"10471"	"ENSG00000204220; ENSG00000206283; ENSG00000224782; ENSG00000235692; ENSG00000237335"	"PFDN6"	"hsa:10471; O15212"	"Cellular proteostasis"	"Prefoldin mediated transfer of substrate  to CCT/TriC"	"2"	"0"	"47.4"	"32.3"	"57.2"	"47.6"	"44.5"	"44.8"	"59.0"	"211.3"	"198.4"	"869.7"	"1312.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BZF1"	"Oxysterol-binding protein-related protein 8 OS=Homo sapiens OX=9606 GN=OSBPL8 PE=1 SV=3"	"0.000"	""	"4"	"3"	"5"	"3"	"889"	"101.1"	"6.96"	"1156.06"	"6.21"	"3"	"2"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf00169, Pf01237"	"114882"	"ENSG00000091039"	"OSBPL8"	"A8K1T2; E9PE66; E9PE68; hsa:114882; Q52LQ3; Q68D75; Q8WXP8; Q9BZF1; Q9P277"	""	"Acyl chain remodelling of PS"	"1"	"0"	"109.9"	"100.4"	"122.7"	"115.1"	"112.1"	"120.7"	"165.5"	"237.8"	"244.5"	"461.0"	"602.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IX18"	"Probable ATP-dependent RNA helicase DHX40 OS=Homo sapiens OX=9606 GN=DHX40 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"779"	"88.5"	"8.65"	"730.90"	"6.20"	"2"	"2"	""	""	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"79665"	"ENSG00000108406"	"DHX40"	"B3KTJ5; C9JR60; hsa:79665; Q5JPH4; Q8IX18; Q8TC86; Q8WY53; Q9BXM1; Q9H6M9"	""	""	"0"	"0"	"44.7"	"36.1"	"49.7"	"54.4"	"45.0"	"48.4"	"52.4"	"215.6"	"244.5"	"639.9"	"817.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q99538"	"Legumain OS=Homo sapiens OX=9606 GN=LGMN PE=1 SV=1"	""	""	"6"	"1"	"1"	"1"	"433"	"49.4"	"6.55"	""	"6.19"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01650"	"5641"	"ENSG00000100600"	"LGMN"	"hsa:5641; O00123; Q86TV2; Q86TV3; Q99538; Q9BTY1"	"Involvement of d-secretase in neurodegenerative diseases"	"MHC class II antigen presentation; Trafficking and processing of endosomal TLR; Vitamin D (calciferol) metabolism"	"4"	"0"	"24.9"	"19.4"	"17.5"	"23.1"	"19.0"	"21.0"	"31.2"	"80.7"	"79.9"	"191.4"	"304.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z2W4"	"Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3"	"0.000"	""	"2"	"2"	"4"	"2"	"902"	"101.4"	"8.40"	"560.38"	"6.18"	"2"	"2"	"stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00644, Pf02825, Pf18606, Pf18633"	"56829"	"ENSG00000105939"	"ZC3HAV1"	"A4D1R2; A4D1S4; hsa:56829; Q7Z2W4; Q8IW57; Q8TAJ3; Q96N79; Q9H8R9; Q9P0Y7"	""	"Signaling by BRAF and RAF1 fusions"	"1"	"0"	"125.3"	"91.2"	"134.3"	"138.1"	"141.4"	"139.8"	"152.5"	"240.9"	"236.1"	"474.1"	"564.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95573"	"Long-chain-fatty-acid--CoA ligase 3 OS=Homo sapiens OX=9606 GN=ACSL3 PE=1 SV=3"	"0.000"	""	"4"	"2"	"3"	"2"	"720"	"80.4"	"8.38"	"319.26"	"6.16"	"1"	"2"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00501"	"2181"	"ENSG00000123983"	"ACSL3"	"hsa:2181; O95573; Q60I92; Q8IUM9"	"Fatty acid beta-oxidation; Fatty acid biosynthesis; Mitochondrial long chain fatty acid beta-oxidation; PPAR signaling pathway; Ferroptosis; Thermogenesis; Ciliary landscape; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Omega-3 / omega-6 fatty acid synthesis; Omega-9 fatty acid synthesis; Fatty acid transporters; Mitochondrial fatty acid oxidation disorders"	"Synthesis of very long-chain fatty acyl-CoAs; Intracellular metabolism of fatty acids regulates insulin secretion"	"14"	"0"	"66.0"	"35.5"	"88.9"	"60.7"	"62.9"	"64.6"	"94.5"	"147.6"	"158.5"	"316.2"	"381.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51858"	"Hepatoma-derived growth factor OS=Homo sapiens OX=9606 GN=HDGF PE=1 SV=1"	"0.000"	""	"10"	"2"	"3"	"2"	"240"	"26.8"	"4.73"	"453.73"	"6.16"	"1"	"2"	"cell organization and biogenesis;signal transduction;other biological processes"	"nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00855"	"3068"	"ENSG00000143321"	"HDGF"	"B3KU21; D3DVC9; hsa:3068; P51858; Q5SZ07; Q5SZ08; Q5SZ09"	"IL-18 signaling pathway"	"XBP1(S) activates chaperone genes"	"2"	"0"	"108.5"	"64.3"	"120.4"	"113.9"	"114.0"	"106.8"	"117.8"	"191.9"	"198.2"	"517.8"	"1214.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13177"	"Serine/threonine-protein kinase PAK 2 OS=Homo sapiens OX=9606 GN=PAK2 PE=1 SV=3"	"0.000"	""	"4"	"2"	"3"	"2"	"524"	"58.0"	"5.96"	"321.21"	"6.15"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069, Pf00786"	"5062"	"ENSG00000180370"	"PAK2"	"hsa:5062; Q13154; Q13177; Q6ISC3"	"Integrin-mediated cell adhesion; Apoptosis-related network due to altered Notch3 in ovarian cancer; Focal adhesion; Fas ligand pathway and stress induction of heat shock proteins; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Ras signaling; Pancreatic adenocarcinoma pathway; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-Merlin signaling dysregulation; Neural crest cell migration during development; Neural crest cell migration in cancer; 3q29 copy number variation syndrome; Pleural mesothelioma; Regulation of actin cytoskeleton; ErbB signaling pathway"	"Regulation of activated PAK-2p34 by proteasome mediated degradation; MAPK6/MAPK4 signaling; RHOV GTPase cycle; Smooth Muscle Contraction; FCERI mediated MAPK activation; Generation of second messenger molecules; Regulation of PAK-2p34 activity by PS-GAP/RHG10; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOJ GTPase cycle; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; RHOU GTPase cycle; Ephrin signaling; Sema3A PAK dependent Axon repulsion; RHO GTPases activate PAKs; VEGFR2 mediated vascular permeability; Activation of RAC1; RHOH GTPase cycle; CD209 (DC-SIGN) signaling; CD28 dependent Vav1 pathway; Nef and signal transduction; Stimulation of the cell death response by PAK-2p34"	"43"	"0"	"7.5"	"7.1"	"9.7"	"6.5"	"6.0"	"6.7"	"10.5"	"41.3"	"48.9"	"267.1"	"646.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92820"	"Gamma-glutamyl hydrolase OS=Homo sapiens OX=9606 GN=GGH PE=1 SV=2"	"0.000"	""	"10"	"3"	"4"	"3"	"318"	"35.9"	"7.11"	"932.37"	"6.15"	"2"	"2"	"other metabolic processes"	"non-structural extracellular;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf07722"	"8836"	"ENSG00000137563"	"GGH"	"hsa:8836; Q92820"	"Fluoropyrimidine activity"	"Neutrophil degranulation"	"2"	"0"	"49.4"	"42.5"	"47.0"	"45.4"	"43.7"	"89.0"	"139.0"	"341.1"	"362.0"	"860.5"	"1323.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14690"	"Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3"	"0.000"	""	"1"	"2"	"4"	"2"	"1871"	"208.6"	"8.87"	"698.09"	"6.14"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00575, Pf05843"	"22984"	"ENSG00000148843"	"PDCD11"	"hsa:22984; Q14690; Q2TA92; Q5W093; Q6P2J3; Q86VQ8; Q9H4P1"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"123.9"	"109.1"	"124.0"	"113.0"	"115.0"	"104.4"	"154.7"	"282.9"	"297.0"	"643.3"	"868.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61353"	"60S ribosomal protein L27 OS=Homo sapiens OX=9606 GN=RPL27 PE=1 SV=2"	"0.000"	""	"12"	"2"	"4"	"2"	"136"	"15.8"	"10.56"	"606.51"	"6.14"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00467, Pf01777"	"6155"	"ENSG00000131469"	"RPL27"	"hsa:6155; P08526; P61353; Q4G0A9"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"15"	"0"	"282.4"	"233.1"	"357.3"	"291.2"	"304.1"	"321.5"	"400.0"	"564.6"	"489.4"	"1143.7"	"1846.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BQ15"	"SOSS complex subunit B1 OS=Homo sapiens OX=9606 GN=NABP2 PE=1 SV=1"	"0.000"	""	"10"	"2"	"4"	"2"	"211"	"22.3"	"9.06"	"705.13"	"6.13"	"2"	"2"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01336"	"79035"	"ENSG00000139579"	"NABP2"	"A6NDF8; hsa:79035; Q6XYC8; Q9BQ15"	"Mesodermal commitment pathway"	"RNA polymerase II transcribes snRNA genes"	"2"	"0"	"142.6"	"99.8"	"151.9"	"167.1"	"144.9"	"153.7"	"175.3"	"275.5"	"275.8"	"562.8"	"770.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UPN3"	"Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4"	"0.000"	""	"1"	"3"	"5"	"3"	"7388"	"837.8"	"5.39"	"964.51"	"6.12"	"3"	"2"	"cell-cell signaling;cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00435, Pf00681, Pf02187, Pf13499, Pf17902, Pf18373"	"23499"	"ENSG00000127603"	"MACF1"	"B1ALC5; E9PJT0; hsa:23499; O75053; Q5VW20; Q8WXY1; Q8WXY2; Q96PK2; Q9H540; Q9UKP0; Q9ULG9; Q9UPN3"	"Mesodermal commitment pathway; Mesodermal commitment pathway"	""	"2"	"0"	"20.8"	"19.4"	"27.7"	"20.3"	"19.0"	"19.6"	"31.0"	"51.4"	"59.4"	"200.7"	"275.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P51397"	"Death-associated protein 1 OS=Homo sapiens OX=9606 GN=DAP PE=1 SV=3"	""	""	"25"	"1"	"1"	"1"	"102"	"11.2"	"9.32"	""	"6.10"	""	"1"	"other metabolic processes;stress response;signal transduction;other biological processes"	""	"other molecular function"	"Pf15228"	"1611"	"ENSG00000112977"	"DAP"	"hsa:1611; P51397; Q6FGC3; Q9BUC9"	""	""	"0"	"0"	"62.2"	"43.1"	"55.4"	"56.0"	"62.2"	"49.7"	"63.0"	"111.2"	"95.7"	"354.2"	"515.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15910"	"Histone-lysine N-methyltransferase EZH2 OS=Homo sapiens OX=9606 GN=EZH2 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"746"	"85.3"	"7.02"	"801.30"	"6.10"	"2"	"2"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00856, Pf11616, Pf18118, Pf18264"	"2146"	"ENSG00000106462"	"EZH2"	"B2RAQ1; B3KS30; B7Z1D6; B7Z7L6; hsa:2146; Q15755; Q15910; Q75MG3; Q92857; Q96FI6"	"Cell differentiation - expanded index; Histone modifications; Endoderm differentiation; Interactome of polycomb repressive complex 2 (PRC2) ; MECP2 and associated Rett syndrome; Tumor suppressor activity of SMARCB1; Epithelial to mesenchymal transition in colorectal cancer; lncRNA in canonical Wnt signaling and colorectal cancer; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; Pleural mesothelioma"	"Defective pyroptosis; HCMV Early Events; Oxidative Stress Induced Senescence; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6; Activation of anterior HOX genes in hindbrain development during early embryogenesis; PKMTs methylate histone lysines; PRC2 methylates histones and DNA"	"19"	"0"	"122.0"	"101.3"	"116.1"	"109.2"	"109.5"	"104.2"	"140.3"	"229.5"	"222.4"	"544.5"	"638.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NRG9"	"Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1"	"0.000"	""	"4"	"2"	"4"	"2"	"546"	"59.5"	"7.50"	"666.01"	"6.09"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus"	""	"Pf00400"	"8086"	"ENSG00000094914"	"AAAS"	"hsa:8086; Q5JB47; Q9NRG9; Q9NWI6; Q9UG19"	""	"SARS-CoV-2 activates/modulates innate and adaptive immune responses; HCMV Early Events; ISG15 antiviral mechanism; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; HCMV Late Events; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; RHOA GTPase cycle"	"29"	"0"	"104.7"	"66.5"	"133.1"	"126.6"	"111.8"	"96.6"	"128.1"	"220.5"	"233.4"	"599.2"	"705.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P18858"	"DNA ligase 1 OS=Homo sapiens OX=9606 GN=LIG1 PE=1 SV=1"	""	""	"4"	"2"	"2"	"2"	"919"	"101.7"	"5.62"	""	"6.09"	""	"2"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01068, Pf04675, Pf04679"	"3978"	"ENSG00000105486"	"LIG1"	"B2RAI8; B4DTU4; hsa:3978; P18858; Q2TB12; Q32P23"	"Base excision repair; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"Gap-filling DNA repair synthesis and ligation in TC-NER; Early Phase of HIV Life Cycle; POLB-Dependent Long Patch Base Excision Repair; PCNA-Dependent Long Patch Base Excision Repair; Processive synthesis on the lagging strand; Gap-filling DNA repair synthesis and ligation in GG-NER; Processive synthesis on the C-strand of the telomere; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"14"	"0"	"21.2"	"22.2"	"29.4"	"27.1"	"24.1"	"28.1"	"25.1"	"53.6"	"59.1"	"131.7"	"202.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UDY4"	"DnaJ homolog subfamily B member 4 OS=Homo sapiens OX=9606 GN=DNAJB4 PE=1 SV=1"	"0.000"	""	"9"	"2"	"4"	"1"	"337"	"37.8"	"8.50"	"615.17"	"6.09"	"2"	"2"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus"	"other molecular function"	"Pf00226, Pf01556"	"11080"	"ENSG00000162616"	"DNAJB4"	"B2R824; hsa:11080; Q13431; Q9UDY4"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"8.4"	"5.5"	"7.4"	"7.3"	"5.9"	"8.2"	"8.7"	"18.0"	"12.3"	"31.0"	"36.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVI1"	"Fanconi anemia group I protein OS=Homo sapiens OX=9606 GN=FANCI PE=1 SV=4"	"0.000"	""	"2"	"2"	"4"	"2"	"1328"	"149.2"	"6.74"	"702.71"	"6.08"	"2"	"2"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf14674, Pf14675, Pf14676, Pf14677, Pf14678, Pf14679, Pf14680"	"55215"	"ENSG00000140525"	"FANCI"	"A4ZVE4; A5YMH4; A6NJZ0; hsa:55215; Q96JN1; Q96ST0; Q9BT96; Q9NVI1"	"Gastric cancer network 2; DNA repair pathways, full network; 15q11q13 copy number variation"	"TP53 Regulates Transcription of DNA Repair Genes; Fanconi Anemia Pathway"	"5"	"0"	"48.0"	"41.7"	"44.4"	"35.6"	"32.8"	"36.9"	"47.5"	"138.8"	"178.2"	"412.6"	"502.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00541"	"Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1"	"0.000"	""	"4"	"2"	"4"	"2"	"588"	"68.0"	"7.33"	"700.47"	"6.07"	"2"	"2"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf06732, Pf16589"	"23481"	"ENSG00000100029"	"PES1"	"hsa:23481; O00541; Q6IC29"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"126.2"	"103.5"	"123.2"	"97.3"	"111.0"	"106.5"	"177.7"	"190.3"	"147.0"	"239.8"	"458.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q99618"	"Cell division cycle-associated protein 3 OS=Homo sapiens OX=9606 GN=CDCA3 PE=1 SV=1"	""	""	"10"	"1"	"1"	"1"	"268"	"29.0"	"6.43"	""	"6.06"	""	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	""	""	"83461"	"ENSG00000111665"	"CDCA3"	"A8K5V6; D3DUS6; hsa:83461; Q99618"	""	""	"0"	"0"	"12.5"	"14.8"	"19.2"	"20.6"	"14.1"	"20.2"	"17.2"	"34.7"	"37.3"	"82.5"	"121.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WUD4"	"Coiled-coil domain-containing protein 12 OS=Homo sapiens OX=9606 GN=CCDC12 PE=1 SV=1"	"0.000"	""	"18"	"2"	"2"	"2"	"166"	"19.2"	"7.34"	"249.26"	"6.06"	"1"	"1"	""	"nucleus"	""	"Pf08315"	"151903"	"ENSG00000160799"	"CCDC12"	"hsa:151903; Q8N8I4; Q8WUD4"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"68.1"	"57.7"	"74.0"	"73.7"	"72.3"	"65.9"	"80.7"	"262.8"	"255.6"	"628.4"	"894.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11532"	"Dystrophin OS=Homo sapiens OX=9606 GN=DMD PE=1 SV=3"	"0.000"	""	"1"	"2"	"3"	"1"	"3685"	"426.5"	"5.88"	"839.26"	"6.06"	"2"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00397, Pf00435, Pf00569, Pf09068, Pf09069"	"1756"	"ENSG00000198947"	"DMD"	"A1L0U9; E7EQR9; E7EQS5; E7ESB2; E9PDN1; E9PDN5; F5GZY3; F8VX32; hsa:1756; P11532; Q02295; Q14169; Q14170; Q5JYU0; Q6NSJ9; Q7KZ48; Q8N754; Q9UCW3; Q9UCW4"	"Arrhythmogenic right ventricular cardiomyopathy; Ectoderm differentiation; Striated muscle contraction pathway; Acute viral myocarditis; Disturbed pathways in Duchenne Muscular Dystrophy; 13q12.12 copy number variation"	"Non-integrin membrane-ECM interactions; Striated Muscle Contraction"	"8"	"0"	"80.6"	"68.4"	"63.1"	"61.1"	"59.9"	"61.5"	"79.8"	"121.2"	"127.5"	"193.9"	"193.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14643"	"Inositol 1,4,5-trisphosphate receptor type 1 OS=Homo sapiens OX=9606 GN=ITPR1 PE=1 SV=3"	"0.000"	""	"1"	"3"	"5"	"1"	"2758"	"313.7"	"6.04"	"966.71"	"6.05"	"3"	"2"	"cell-cell signaling;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf00520, Pf01365, Pf02815, Pf08454, Pf08709"	"3708"	"ENSG00000150995"	"ITPR1"	"E7EPX7; E9PDE9; hsa:3708; Q14643; Q14660; Q99897"	"Alzheimer's disease and miRNA effects; Myometrial relaxation and contraction pathways; G protein signaling pathways; Cell-type dependent selectivity of CCK2R signaling; Resistin as a regulator of inflammation; Fragile X syndrome; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Vitamin D-sensitive calcium signaling in depression; PKC-gamma calcium signaling pathway in ataxia; Type I collagen synthesis in the context of osteogenesis imperfecta; GPR143 in melanocytes and retinal pigment epithelium cells; STING pathway in Kawasaki-like disease and COVID-19; Alzheimer's disease; GDNF signaling; Calcium regulation in cardiac cells; 15q25 copy number variation; T-cell receptor signaling pathway; Serotonin HTR1 group and FOS pathway; Serotonin receptor 2 and ELK-SRF/GATA4 signaling"	"Role of phospholipids in phagocytosis; FCERI mediated Ca+2 mobilization; FCGR3A-mediated IL10 synthesis; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Ion homeostasis; cGMP effects; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Ca2+ pathway; VEGFR2 mediated cell proliferation; Elevation of cytosolic Ca2+ levels; PLC beta mediated events; DAG and IP3 signaling; CLEC7A (Dectin-1) induces NFAT activation; Effects of PIP2 hydrolysis"	"34"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NZM3"	"Intersectin-2 OS=Homo sapiens OX=9606 GN=ITSN2 PE=1 SV=3"	"0.000"	""	"1"	"2"	"3"	"2"	"1697"	"193.3"	"8.12"	"319.35"	"6.04"	"1"	"2"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00018, Pf00168, Pf00621, Pf07653, Pf12763, Pf14604, Pf16652"	"50618"	"ENSG00000198399"	"ITSN2"	"hsa:50618; O95062; Q15812; Q9HAK4; Q9NXE6; Q9NYG0; Q9NZM2; Q9NZM3; Q9ULG4"	""	"Cargo recognition for clathrin-mediated endocytosis; RHOU GTPase cycle"	"3"	"0"	"31.9"	"21.6"	"33.7"	"34.1"	"34.8"	"54.3"	"102.6"	"166.1"	"174.8"	"252.5"	"242.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NR50"	"Translation initiation factor eIF-2B subunit gamma OS=Homo sapiens OX=9606 GN=EIF2B3 PE=1 SV=1"	"0.000"	""	"4"	"2"	"3"	"2"	"452"	"50.2"	"6.47"	"357.30"	"6.04"	"1"	"2"	"protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00483"	"8891"	"ENSG00000070785"	"EIF2B3"	"B2RBH8; D3DPZ2; hsa:8891; Q5QP89; Q5QP90; Q8NDB5; Q8WV57; Q9H850; Q9NR50"	"Translation factors; Primary ovarian insufficiency"	"Recycling of eIF2:GDP"	"3"	"0"	"27.6"	"25.9"	"34.6"	"28.5"	"31.8"	"23.1"	"35.3"	"97.4"	"93.8"	"275.2"	"483.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52294"	"Importin subunit alpha-5 OS=Homo sapiens OX=9606 GN=KPNA1 PE=1 SV=3"	"0.000"	""	"8"	"3"	"4"	"1"	"538"	"60.2"	"5.01"	"653.82"	"6.03"	"2"	"2"	"cell-cell signaling;cell cycle OR cell proliferation;transport;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00514, Pf01749, Pf16186"	"3836"	"ENSG00000114030"	"KPNA1"	"D3DN93; hsa:3836; P52294; Q6IBQ9; Q9BQ56"	"Ebola virus infection in host"	"ISG15 antiviral mechanism; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Vpr-mediated nuclear import of PICs; Apoptosis induced DNA fragmentation; Interferon alpha/beta signaling; Assembly of the ORC complex at the origin of replication; Integration of provirus; Inhibition of nitric oxide production"	"10"	"0"	"10.3"	"8.2"	"11.1"	"8.5"	"6.8"	"7.1"	"12.7"	"29.0"	"27.6"	"73.2"	"129.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z478"	"ATP-dependent RNA helicase DHX29 OS=Homo sapiens OX=9606 GN=DHX29 PE=1 SV=2"	"0.000"	""	"4"	"5"	"8"	"5"	"1369"	"155.1"	"8.09"	"1710.60"	"6.03"	"5"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"54505"	"ENSG00000067248"	"DHX29"	"hsa:54505; O75549; Q63HN0; Q63HN3; Q7Z478; Q8IWW2; Q8N3A1; Q9UMH2"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"174.4"	"139.6"	"166.4"	"137.7"	"162.4"	"167.2"	"194.7"	"385.9"	"347.1"	"1042.0"	"1398.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A5PLN9"	"Trafficking protein particle complex subunit 13 OS=Homo sapiens OX=9606 GN=TRAPPC13 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"417"	"46.5"	"5.60"	"574.11"	"6.02"	"1"	"1"	"cell organization and biogenesis;transport"	"cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf06159"	"80006"	"ENSG00000113597"	"TRAPPC13"	"A5PLN9; hsa:80006; Q17RZ9; Q49A23; Q4JHG0; Q6MZG4; Q8TCM2; Q9H8I3"	""	"RAB GEFs exchange GTP for GDP on RABs"	"1"	"0"	"12.1"	"8.6"	"9.5"	"9.7"	"11.7"	"10.3"	"24.0"	"105.6"	"104.2"	"255.6"	"468.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75689"	"Arf-GAP with dual PH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ADAP1 PE=1 SV=2"	"0.000"	""	"10"	"4"	"6"	"4"	"374"	"43.4"	"8.97"	"1256.24"	"6.02"	"4"	"2"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf01412"	"11033"	"ENSG00000105963"	"ADAP1"	"A4D2Q2; B3KRZ4; B4DVA6; F6XZ68; H7C2Q4; hsa:11033; O75689"	""	"Nuclear signaling by ERBB4"	"1"	"0"	"147.7"	"109.3"	"151.1"	"154.8"	"147.7"	"288.4"	"467.6"	"1120.9"	"1105.2"	"1313.3"	"1089.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4W2"	"Ribosomal biogenesis protein LAS1L OS=Homo sapiens OX=9606 GN=LAS1L PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"734"	"83.0"	"4.73"	"734.02"	"6.00"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf04031"	"81887"	"ENSG00000001497"	"LAS1L"	"A9X410; hsa:81887; Q5JXQ0; Q8TEN5; Q9H9V5; Q9Y4W2"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"24.2"	"34.1"	"27.0"	"25.2"	"24.2"	"16.5"	"34.3"	"68.6"	"55.3"	"173.9"	"303.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5M775"	"Cytospin-B OS=Homo sapiens OX=9606 GN=SPECC1 PE=1 SV=1"	"0.000"	""	"3"	"2"	"4"	"2"	"1068"	"118.5"	"6.70"	"797.44"	"6.00"	"2"	"2"	"cell organization and biogenesis;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	""	"Pf00307"	"92521"	"ENSG00000128487"	"SPECC1"	"B4DHH0; B7WNS8; hsa:92521; Q5IBP1; Q5IBP2; Q5IBP3; Q5IBP4; Q5M772; Q5M773; Q5M774; Q5M775; Q86XT8; Q8N4U4; Q8WU84; Q9HCQ3"	""	""	"0"	"0"	"46.4"	"26.8"	"35.4"	"33.3"	"33.1"	"29.9"	"36.9"	"79.9"	"65.5"	"132.0"	"220.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86U06"	"Probable RNA-binding protein 23 OS=Homo sapiens OX=9606 GN=RBM23 PE=1 SV=1"	"0.000"	""	"5"	"2"	"4"	"1"	"439"	"48.7"	"9.85"	"550.17"	"6.00"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf15519"	"55147"	"ENSG00000100461"	"RBM23"	"D3DS32; hsa:55147; Q86U06; Q8ND16; Q8TB88; Q8WY40; Q9BUJ1; Q9NVV7"	""	""	"0"	"0"	"10.2"	"4.9"	"9.7"	"6.6"	"7.8"	"5.2"	"7.7"	"15.0"	"14.3"	"28.9"	"42.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q05823"	"2-5A-dependent ribonuclease OS=Homo sapiens OX=9606 GN=RNASEL PE=1 SV=2"	"0.000"	""	"3"	"2"	"3"	"2"	"741"	"83.5"	"6.65"	"400.45"	"6.00"	"1"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00023, Pf00069, Pf06479"	"6041"	"ENSG00000135828"	"RNASEL"	"hsa:6041; Q05823; Q5W0L2; Q6AI46"	""	"OAS antiviral response; Interferon alpha/beta signaling"	"2"	"0"	"7.6"	"8.6"	"11.6"	"14.4"	"10.7"	"11.8"	"13.1"	"26.6"	"36.6"	"84.9"	"67.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15276"	"Rab GTPase-binding effector protein 1 OS=Homo sapiens OX=9606 GN=RABEP1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"862"	"99.2"	"5.01"	"596.37"	"6.00"	"1"	"1"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"other membranes;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf03528, Pf09311"	"9135"	"ENSG00000029725"	"RABEP1"	"B2RAG7; hsa:9135; O95369; Q15276; Q8IVX3"	"GDNF signaling"	"TBC/RABGAPs"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H6U6"	"Breast carcinoma-amplified sequence 3 OS=Homo sapiens OX=9606 GN=BCAS3 PE=1 SV=3"	"0.000"	""	"3"	"2"	"3"	"2"	"928"	"101.2"	"6.70"	"379.77"	"5.99"	"1"	"2"	"cell-cell signaling;other metabolic processes;stress response;developmental processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf12490"	"54828"	"ENSG00000141376"	"BCAS3"	"hsa:54828; Q17RM0; Q6KF21; Q8IXI6; Q8NDR8; Q8TDL9; Q8TDM1; Q8WY55; Q9BVF0; Q9H6U6; Q9H957; Q9H9Y9; Q9NXP4"	"Ectoderm differentiation"	""	"1"	"0"	"32.9"	"22.4"	"23.1"	"22.2"	"24.5"	"26.3"	"36.5"	"56.9"	"68.2"	"124.4"	"127.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NPJ3"	"Acyl-coenzyme A thioesterase 13 OS=Homo sapiens OX=9606 GN=ACOT13 PE=1 SV=1"	"0.000"	""	"18"	"2"	"4"	"2"	"140"	"15.0"	"9.14"	"582.48"	"5.99"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;mitochondrion"	"other molecular function"	"Pf03061"	"55856"	"ENSG00000112304"	"ACOT13"	"F5H2L4; hsa:55856; O95549; Q9NPJ3"	""	"Mitochondrial Fatty Acid Beta-Oxidation"	"1"	"0"	"25.8"	"17.1"	"20.7"	"23.1"	"25.1"	"22.1"	"31.2"	"56.6"	"61.8"	"137.6"	"192.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60763"	"General vesicular transport factor p115 OS=Homo sapiens OX=9606 GN=USO1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"962"	"107.8"	"4.91"	"452.30"	"5.97"	"1"	"1"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	""	"Pf04869, Pf04871, Pf18770"	"8615"	"ENSG00000138768"	"USO1"	"B2RAQ0; hsa:8615; O60763; Q6PK63; Q86TB8; Q8N592"	""	"COPI-mediated anterograde transport; COPII-mediated vesicle transport; Golgi Cisternae Pericentriolar Stack Reorganization"	"3"	"0"	"30.2"	"23.9"	"39.3"	"40.4"	"29.6"	"41.8"	"43.1"	"62.0"	"54.0"	"70.1"	"85.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96GA3"	"Protein LTV1 homolog OS=Homo sapiens OX=9606 GN=LTV1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"4"	"1"	"475"	"54.8"	"4.91"	"734.73"	"5.97"	"1"	"1"	"transport;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf04180"	"84946"	"ENSG00000135521"	"LTV1"	"hsa:84946; Q96GA3; Q96JX8"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"34.2"	"27.8"	"36.9"	"32.0"	"39.2"	"29.9"	"41.1"	"62.8"	"53.6"	"86.2"	"125.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95453"	"Poly(A)-specific ribonuclease PARN OS=Homo sapiens OX=9606 GN=PARN PE=1 SV=1"	"0.000"	""	"3"	"2"	"3"	"2"	"639"	"73.4"	"6.20"	"288.69"	"5.96"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04857, Pf08675"	"5073"	"ENSG00000140694; ENSG00000274829"	"PARN"	"B2RCB3; B4DDG8; B4DSB0; B4DWR4; B4E1H6; hsa:5073; O95453"	"Lung fibrosis"	"Deadenylation of mRNA; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA"	"4"	"0"	"122.4"	"92.4"	"111.2"	"102.7"	"98.5"	"95.1"	"150.4"	"239.3"	"254.8"	"919.3"	"1597.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y4Y9"	"U6 snRNA-associated Sm-like protein LSm5 OS=Homo sapiens OX=9606 GN=LSM5 PE=1 SV=3"	""	""	"25"	"1"	"1"	"1"	"91"	"9.9"	"4.54"	""	"5.96"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01423"	"23658"	"ENSG00000106355"	"LSM5"	"hsa:23658; Q9Y4Y9"	""	"mRNA Splicing - Major Pathway; mRNA decay by 5' to 3' exoribonuclease"	"2"	"0"	"11.9"	"9.2"	"14.6"	"15.4"	"10.6"	"13.6"	"13.7"	"29.3"	"25.7"	"76.1"	"140.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2S7"	"Polymerase delta-interacting protein 2 OS=Homo sapiens OX=9606 GN=POLDIP2 PE=1 SV=1"	"0.000"	""	"6"	"2"	"4"	"2"	"368"	"42.0"	"8.63"	"718.27"	"5.96"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytoskeleton;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity"	"Pf04379, Pf08755"	"26073"	"ENSG00000004142"	"POLDIP2"	"B2R846; hsa:26073; Q96JE4; Q9Y2S7"	""	""	"0"	"0"	"116.1"	"99.3"	"97.2"	"98.7"	"96.9"	"107.2"	"131.3"	"159.3"	"190.5"	"365.5"	"894.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9BU23"	"Lipase maturation factor 2 OS=Homo sapiens OX=9606 GN=LMF2 PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"707"	"79.6"	"10.10"	""	"5.95"	""	"1"	"protein metabolism;other metabolic processes"	"other membranes;ER/Golgi"	""	"Pf06762"	"91289"	"ENSG00000100258"	"LMF2"	"A6NEZ0; hsa:91289; Q13392; Q6ZNR2; Q8WU74; Q96C62; Q9BU23"	""	"Assembly of active LPL and LIPC lipase complexes"	"1"	"0"	"10.9"	"7.8"	"10.0"	"8.8"	"10.5"	"6.2"	"13.9"	"17.8"	"15.5"	"24.3"	"28.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75348"	"V-type proton ATPase subunit G 1 OS=Homo sapiens OX=9606 GN=ATP6V1G1 PE=1 SV=3"	"0.000"	""	"17"	"2"	"4"	"2"	"118"	"13.7"	"8.79"	"726.97"	"5.91"	"2"	"2"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf03179"	"9550"	"ENSG00000136888"	"ATP6V1G1"	"hsa:9550; O75348; Q6IB33"	"Osteoclast signaling; Proximal tubule transport"	"Amino acids regulate mTORC1; ROS and RNS production in phagocytes; Insulin receptor recycling; Transferrin endocytosis and recycling; Ion channel transport"	"7"	"0"	"189.7"	"159.0"	"149.4"	"160.6"	"155.4"	"149.4"	"199.3"	"310.5"	"276.2"	"555.6"	"773.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKN8"	"General transcription factor 3C polypeptide 4 OS=Homo sapiens OX=9606 GN=GTF3C4 PE=1 SV=2"	"0.000"	""	"4"	"3"	"4"	"3"	"822"	"91.9"	"6.65"	"651.28"	"5.91"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf12657, Pf12660, Pf19336"	"9329"	"ENSG00000125484"	"GTF3C4"	"hsa:9329; Q5VZJ7; Q9UKN8"	""	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter"	"3"	"0"	"21.9"	"13.9"	"17.9"	"16.5"	"20.3"	"12.9"	"24.7"	"61.9"	"68.9"	"254.6"	"388.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14240"	"Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2"	"0.000"	""	"6"	"2"	"4"	"1"	"407"	"46.4"	"5.48"	"720.77"	"5.90"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"1974"	"ENSG00000156976"	"EIF4A2"	"D3DNU9; hsa:1974; Q14240; Q53XJ6; Q96B90; Q96EA8"	"Translation factors; Translation inhibitors in chronically activated PDGFRA cells"	"Deadenylation of mRNA; ISG15 antiviral mechanism; L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Translation initiation complex formation; Ribosomal scanning and start codon recognition"	"9"	"1"	"160.2"	"119.3"	"193.6"	"160.8"	"146.4"	"150.4"	"186.8"	"245.2"	"242.6"	"393.6"	"603.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O95229"	"ZW10 interactor OS=Homo sapiens OX=9606 GN=ZWINT PE=1 SV=2"	""	""	"13"	"2"	"2"	"2"	"277"	"31.3"	"5.15"	""	"5.90"	""	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf15556"	"11130"	"ENSG00000122952"	"ZWINT"	"A6NNV6; hsa:11130; O95229; Q0D2I3; Q9BWD0"	""	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"6"	"0"	"6.0"	"4.7"	"9.0"	"4.4"	"4.6"	"5.4"	"5.8"	"11.4"	"12.5"	"23.5"	"35.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UNP9"	"Peptidyl-prolyl cis-trans isomerase E OS=Homo sapiens OX=9606 GN=PPIE PE=1 SV=1"	"0.000"	""	"7"	"2"	"4"	"1"	"301"	"33.4"	"5.60"	"791.69"	"5.90"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00160"	"10450"	"ENSG00000084072"	"PPIE"	"B2R971; hsa:10450; O43634; O43635; Q32Q72; Q3S611; Q5TGA0; Q5TGA2; Q5TGA3; Q9UIZ5; Q9UNP9"	""	"mRNA Splicing - Major Pathway; Neutrophil degranulation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	"6"	"0"	"92.8"	"78.6"	"109.9"	"93.1"	"100.2"	"103.1"	"107.7"	"160.3"	"142.8"	"357.2"	"693.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UQN3"	"Charged multivesicular body protein 2b OS=Homo sapiens OX=9606 GN=CHMP2B PE=1 SV=1"	"0.000"	""	"12"	"3"	"5"	"3"	"213"	"23.9"	"8.76"	"1058.79"	"5.90"	"3"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf03357"	"25978"	"ENSG00000083937"	"CHMP2B"	"B4DJG8; hsa:25978; Q53HC7; Q9UQN3; Q9Y4U6"	""	"Macroautophagy; Budding and maturation of HIV virion; Endosomal Sorting Complex Required For Transport (ESCRT); HCMV Late Events; Sealing of the nuclear envelope (NE) by ESCRT-III; Late endosomal microautophagy; Pyroptosis; Translation of Replicase and Assembly of the Replication Transcription Complex; Translation of Replicase and Assembly of the Replication Transcription Complex"	"9"	"0"	"287.4"	"253.3"	"285.6"	"312.5"	"294.5"	"287.5"	"332.8"	"490.2"	"484.1"	"1125.0"	"1207.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NYY8"	"FAST kinase domain-containing protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=FASTKD2 PE=1 SV=1"	"0.000"	""	"3"	"2"	"4"	"2"	"710"	"81.4"	"8.05"	"667.19"	"5.90"	"2"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"mitochondrion;other cell component"	"nucleic acid binding activity"	"Pf06743, Pf08368, Pf08373"	"22868"	"ENSG00000118246"	"FASTKD2"	"hsa:22868; Q9NVX6; Q9NYY8; Q9Y2H7"	""	""	"0"	"0"	"150.9"	"108.6"	"142.7"	"121.9"	"116.5"	"125.0"	"170.7"	"273.2"	"249.4"	"704.1"	"1111.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13489"	"Ribonuclease inhibitor OS=Homo sapiens OX=9606 GN=RNH1 PE=1 SV=2"	"0.000"	""	"5"	"2"	"4"	"2"	"461"	"49.9"	"4.82"	"645.11"	"5.90"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf13516, Pf18779"	"6050"	"ENSG00000023191; ENSG00000276230"	"RNH1"	"hsa:6050; P13489; Q8IZK8; Q96FD7; Q9BQ80; Q9UDK6"	""	""	"0"	"0"	"15.5"	"11.8"	"23.2"	"18.8"	"19.6"	"15.7"	"19.7"	"40.2"	"44.8"	"99.0"	"117.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96Q89"	"Kinesin-like protein KIF20B OS=Homo sapiens OX=9606 GN=KIF20B PE=1 SV=3"	"0.000"	""	"1"	"2"	"4"	"2"	"1820"	"210.5"	"5.67"	"692.03"	"5.89"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225"	"9585"	"ENSG00000138182"	"KIF20B"	"A8MXM7; hsa:9585; O43277; Q09471; Q2KQ73; Q32NE1; Q561V3; Q58EX8; Q5T9M8; Q5T9M9; Q5T9N0; Q5T9N1; Q7KZ68; Q7Z5E0; Q7Z5E1; Q7Z6M9; Q86X82; Q96Q89; Q9H3R8; Q9H6Q9; Q9H755; Q9NTC1; Q9UFR5"	"Gastric cancer network 1"	"COPI-dependent Golgi-to-ER retrograde traffic; Kinesins"	"3"	"0"	"86.8"	"82.2"	"73.5"	"79.5"	"61.2"	"72.4"	"93.3"	"105.0"	"101.9"	"145.8"	"192.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BVC5"	"Ashwin OS=Homo sapiens OX=9606 GN=C2orf49 PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"232"	"25.8"	"9.74"	"552.83"	"5.88"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes"	"nucleus;other cell component"	""	"Pf15323"	"79074"	"ENSG00000135974"	"C2orf49"	"B3KXN3; B4E2G9; hsa:79074; Q9BVC5"	""	"tRNA processing in the nucleus"	"1"	"0"	"111.2"	"83.9"	"107.1"	"100.5"	"102.3"	"94.5"	"129.4"	"174.6"	"160.3"	"278.8"	"354.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13601"	"KRR1 small subunit processome component homolog OS=Homo sapiens OX=9606 GN=KRR1 PE=1 SV=4"	"0.000"	""	"5"	"3"	"5"	"3"	"381"	"43.6"	"9.77"	"1309.27"	"5.87"	"3"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf17903"	"11103"	"ENSG00000111615"	"KRR1"	"A0FIK6; A0JLP0; B2R989; E7EUQ0; hsa:11103; Q13601; Q8NEA8; Q8TC37; Q96AT5"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"334.5"	"305.4"	"338.9"	"321.9"	"335.5"	"347.6"	"433.7"	"719.2"	"646.9"	"1127.6"	"1360.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P43034"	"Platelet-activating factor acetylhydrolase IB subunit alpha OS=Homo sapiens OX=9606 GN=PAFAH1B1 PE=1 SV=2"	"0.000"	""	"6"	"3"	"5"	"3"	"410"	"46.6"	"7.37"	"838.01"	"5.86"	"3"	"2"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400, Pf08513"	"5048"	"ENSG00000007168"	"PAFAH1B1"	"B2R7Q7; hsa:5048; P43034; Q8WZ88; Q8WZ89"	"Wnt signaling pathway and pluripotency; Ciliary landscape; Neurogenesis regulation in the olfactory epithelium; PAFAH1B1 copy number variation"	"Resolution of Sister Chromatid Cohesion; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Separation of Sister Chromatids; RHO GTPases Activate Formins; COPI-independent Golgi-to-ER retrograde traffic; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"18"	"0"	"133.1"	"98.0"	"138.4"	"117.3"	"125.7"	"117.1"	"144.8"	"398.1"	"397.4"	"1334.5"	"2082.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UMN6"	"Histone-lysine N-methyltransferase 2B OS=Homo sapiens OX=9606 GN=KMT2B PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"2715"	"293.3"	"8.22"	"643.72"	"5.86"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00628, Pf00856, Pf02008, Pf05964, Pf05965, Pf13771"	"9757"	"ENSG00000272333"	"KMT2B"	"O15022; O95836; Q96GP2; Q96IP3; Q9UK25; Q9UMN6; Q9Y668; Q9Y669"	"Histone modifications"	"PKMTs methylate histone lysines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Formation of WDR5-containing histone-modifying complexes"	"4"	"0"	"60.3"	"48.0"	"56.5"	"49.9"	"50.6"	"50.4"	"69.6"	"115.4"	"115.6"	"288.3"	"430.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IWA0"	"WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1"	"0.000"	""	"3"	"2"	"3"	"2"	"830"	"94.4"	"5.96"	"313.79"	"5.85"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf00400"	"84128"	"ENSG00000115368"	"WDR75"	"hsa:84128; Q8IWA0; Q96J10; Q9H8U8; Q9H9U5; Q9H9V8; Q9UIX2"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"63.3"	"54.3"	"82.2"	"81.8"	"67.0"	"65.1"	"73.1"	"127.4"	"153.8"	"303.3"	"391.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43432"	"Eukaryotic translation initiation factor 4 gamma 3 OS=Homo sapiens OX=9606 GN=EIF4G3 PE=1 SV=2"	"0.000"	""	"1"	"2"	"4"	"1"	"1585"	"176.5"	"5.38"	"742.69"	"5.84"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf02020, Pf02847, Pf02854"	"8672"	"ENSG00000075151"	"EIF4G3"	"B9EGQ7; hsa:8672; O43432; Q15597; Q504Z1; Q5SWC3; Q8NEN1"	"Translation factors; Translation inhibitors in chronically activated PDGFRA cells"	"ISG15 antiviral mechanism"	"3"	"0"	"68.4"	"54.9"	"75.1"	"70.8"	"68.0"	"60.4"	"79.6"	"130.5"	"136.5"	"277.4"	"325.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N1B4"	"Vacuolar protein sorting-associated protein 52 homolog OS=Homo sapiens OX=9606 GN=VPS52 PE=1 SV=1"	"0.000"	""	"2"	"1"	"3"	"1"	"723"	"82.2"	"5.99"	"315.29"	"5.84"	"1"	"1"	"transport;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf04129"	"6293"	"ENSG00000206286; ENSG00000223501; ENSG00000224455; ENSG00000225590; ENSG00000228425; ENSG00000236014"	"VPS52"	"A2BF38; B0UZZ4; B4DNI9; hsa:6293; Q53GR4; Q5JPA0; Q5SQW1; Q8IUN6; Q8N1B4; Q9NPT5"	""	"Retrograde transport at the Trans-Golgi-Network"	"1"	"0"	"20.4"	"14.6"	"20.7"	"22.0"	"18.8"	"14.0"	"24.7"	"39.7"	"45.1"	"79.6"	"82.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NTX5"	"Ethylmalonyl-CoA decarboxylase OS=Homo sapiens OX=9606 GN=ECHDC1 PE=1 SV=2"	"0.000"	""	"4"	"1"	"3"	"1"	"307"	"33.7"	"8.21"	"256.42"	"5.83"	"1"	"1"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf00378"	"55862"	"ENSG00000093144"	"ECHDC1"	"A6NFJ5; B7Z8S0; E9PEN7; E9PR31; F8W851; hsa:55862; Q5TEF6; Q5TEF7; Q5TEG0; Q5TEG4; Q9NTX5; Q9NZ30; V9HW18"	"Fatty acid biosynthesis"	""	"1"	"0"	"4.5"	"2.9"	"9.9"	"7.6"	"5.1"	"7.6"	"15.1"	"70.3"	"78.9"	"217.3"	"305.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P07858"	"Cathepsin B OS=Homo sapiens OX=9606 GN=CTSB PE=1 SV=3"	""	""	"5"	"2"	"2"	"2"	"339"	"37.8"	"6.30"	""	"5.82"	""	"2"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00112, Pf08127"	"1508"	"ENSG00000164733; ENSG00000285132"	"CTSB"	"B3KQR5; B3KRR5; hsa:1508; P07858; Q503A6; Q96D87"	"Ebola virus infection in host; 8p23.1 copy number variation syndrome"	"Neutrophil degranulation; MHC class II antigen presentation; Collagen degradation; Assembly of collagen fibrils and other multimeric structures; Trafficking and processing of endosomal TLR"	"7"	"0"	"88.9"	"71.4"	"83.9"	"83.2"	"80.7"	"77.1"	"108.9"	"221.3"	"206.1"	"658.1"	"1481.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NR33"	"DNA polymerase epsilon subunit 4 OS=Homo sapiens OX=9606 GN=POLE4 PE=1 SV=2"	"0.000"	""	"18"	"2"	"3"	"2"	"117"	"12.2"	"4.92"	"304.74"	"5.82"	"1"	"2"	"DNA metabolism;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00808"	"56655"	"ENSG00000115350"	"POLE4"	"hsa:56655; Q53TR2; Q9NR33"	"Pyrimidine metabolism; Base excision repair; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"Activation of the pre-replicative complex; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; DNA replication initiation; Gap-filling DNA repair synthesis and ligation in GG-NER"	"16"	"0"	"21.8"	"18.9"	"25.0"	"18.8"	"19.3"	"20.4"	"31.1"	"59.5"	"56.6"	"111.4"	"202.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HCG8"	"Pre-mRNA-splicing factor CWC22 homolog OS=Homo sapiens OX=9606 GN=CWC22 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"908"	"105.4"	"7.03"	"514.08"	"5.81"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity"	"Pf02847"	"57703"	"ENSG00000163510"	"CWC22"	"hsa:57703; Q05DC2; Q4G135; Q52LF0; Q6PEX2; Q7Z6I0; Q9H5L3; Q9H6Q6; Q9HCG8"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"33.9"	"24.2"	"32.9"	"22.1"	"23.3"	"35.9"	"41.8"	"60.4"	"53.9"	"192.1"	"384.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P31151"	"Protein S100-A7 OS=Homo sapiens OX=9606 GN=S100A7 PE=1 SV=4"	"0.000"	""	"35"	"3"	"4"	"3"	"101"	"11.5"	"6.77"	"1000.97"	"5.81"	"2"	"2"	"stress response;developmental processes;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01023"	"6278"	"ENSG00000143556"	"S100A7"	"hsa:6278; P31151; Q5SY67; Q6FGE3; Q9H1E2"	""	"Neutrophil degranulation; Metal sequestration by antimicrobial proteins"	"2"	"0"	"99.3"	"124.3"	"427.1"	"360.0"	"217.6"	"107.5"	"148.8"	"292.0"	"321.9"	"1238.0"	"794.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46821"	"Microtubule-associated protein 1B OS=Homo sapiens OX=9606 GN=MAP1B PE=1 SV=2"	"0.000"	""	"1"	"2"	"4"	"2"	"2468"	"270.5"	"4.81"	"685.95"	"5.81"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00414"	"4131"	"ENSG00000131711"	"MAP1B"	"A2BDK5; hsa:4131; P46821"	"Microtubule cytoskeleton regulation; Fragile X syndrome; Neurogenesis regulation in the olfactory epithelium"	""	"3"	"0"	"101.8"	"85.4"	"104.1"	"91.3"	"98.9"	"112.9"	"123.8"	"194.8"	"204.7"	"317.2"	"394.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6IQ49"	"Replication stress response regulator SDE2 OS=Homo sapiens OX=9606 GN=SDE2 PE=1 SV=1"	"0.000"	""	"8"	"3"	"5"	"3"	"451"	"49.7"	"6.05"	"1108.46"	"5.78"	"3"	"2"	"cell cycle OR cell proliferation;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity"	"Pf13019, Pf13297"	"163859"	"ENSG00000143751"	"SDE2"	"A8K4P3; hsa:163859; Q5TD36; Q6IQ49; Q6ZS26; Q8NAG7"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"620.9"	"531.5"	"611.4"	"582.6"	"532.2"	"494.9"	"655.2"	"990.7"	"1009.5"	"1820.5"	"2281.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50914"	"60S ribosomal protein L14 OS=Homo sapiens OX=9606 GN=RPL14 PE=1 SV=4"	"0.000"	""	"9"	"2"	"3"	"2"	"215"	"23.4"	"10.93"	"290.38"	"5.78"	"1"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01929"	"9045"	"ENSG00000188846"	"RPL14"	"hsa:9045; P50914; Q45RF0; Q53G20; Q8TBD5; Q8WUT0; Q92579; Q96GR0; Q9BSB8; Q9BW65; Q9BYF6"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"88.1"	"63.6"	"116.9"	"94.9"	"195.1"	"104.0"	"118.0"	"171.9"	"182.5"	"378.3"	"577.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00442"	"RNA 3'-terminal phosphate cyclase OS=Homo sapiens OX=9606 GN=RTCA PE=1 SV=1"	"0.000"	""	"3"	"1"	"4"	"1"	"366"	"39.3"	"7.85"	"570.35"	"5.78"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf01137, Pf05189"	"8634"	"ENSG00000137996"	"RTCA"	"hsa:8634; O00442; Q5VVL5; Q5VVL6; Q96E99"	""	""	"0"	"0"	"26.0"	"14.2"	"29.2"	"24.1"	"20.6"	"26.7"	"36.5"	"71.2"	"87.7"	"268.2"	"345.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96IZ7"	"Serine/Arginine-related protein 53 OS=Homo sapiens OX=9606 GN=RSRC1 PE=1 SV=1"	"0.000"	""	"7"	"2"	"4"	"2"	"334"	"38.7"	"11.08"	"601.04"	"5.77"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	""	""	"51319"	"ENSG00000174891"	"RSRC1"	"A8K2R9; hsa:51319; Q96IZ7; Q96QK2; Q9NZE5"	""	""	"0"	"0"	"75.8"	"65.8"	"81.1"	"65.6"	"67.7"	"63.9"	"80.4"	"114.5"	"106.3"	"261.0"	"422.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NX24"	"H/ACA ribonucleoprotein complex subunit 2 OS=Homo sapiens OX=9606 GN=NHP2 PE=1 SV=1"	"0.000"	""	"19"	"2"	"4"	"2"	"153"	"17.2"	"8.22"	"846.92"	"5.77"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf01248"	"55651"	"ENSG00000145912"	"NHP2"	"A6NKY8; hsa:55651; Q9NX24; Q9P095"	""	"rRNA modification in the nucleus and cytosol; Telomere Extension By Telomerase"	"2"	"0"	"97.9"	"76.7"	"96.9"	"99.5"	"78.6"	"77.9"	"101.9"	"315.5"	"326.9"	"641.1"	"704.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15283"	"Ras GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=RASA2 PE=1 SV=3"	"0.000"	""	"1"	"1"	"4"	"1"	"850"	"96.6"	"7.20"	"525.94"	"5.73"	"1"	"1"	"signal transduction;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00168, Pf00169, Pf00616, Pf00779"	"5922"	"ENSG00000155903"	"RASA2"	"A8K7K1; G3V0F9; hsa:5922; O00695; Q15283; Q15284; Q92594; Q99577; Q9UEQ2"	"MAPK signaling pathway; Ebola virus infection in host; Ras signaling; Modulators of TCR signaling and T cell activation"	"Regulation of RAS by GAPs"	"5"	"0"	"4.6"	"0.0"	"4.8"	"3.9"	"6.1"	"8.9"	"28.0"	"59.5"	"46.1"	"52.2"	"59.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60293"	"Zinc finger C3H1 domain-containing protein OS=Homo sapiens OX=9606 GN=ZFC3H1 PE=1 SV=3"	"0.000"	""	"2"	"3"	"5"	"3"	"1989"	"226.2"	"8.13"	"1308.60"	"5.72"	"3"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf10650"	"196441"	"ENSG00000133858"	"ZFC3H1"	"hsa:196441; O60293; Q6GMU1; Q6P2S9; Q6ZV36; Q96BE7"	""	""	"0"	"0"	"97.9"	"91.8"	"105.4"	"87.1"	"82.2"	"90.4"	"127.8"	"151.7"	"140.7"	"234.9"	"286.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O43678"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 OS=Homo sapiens OX=9606 GN=NDUFA2 PE=1 SV=3"	""	""	"21"	"1"	"1"	"1"	"99"	"10.9"	"9.57"	""	"5.72"	""	"1"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes"	"other membranes;mitochondrion"	"transporter activity"	"Pf05047"	"4695"	"ENSG00000131495"	"NDUFA2"	"D6RJD6; hsa:4695; O43678; Q6IAY8"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"17.5"	"11.5"	"16.4"	"18.0"	"17.1"	"15.3"	"30.3"	"55.7"	"53.1"	"126.6"	"141.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49327"	"Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3"	"0.000"	""	"1"	"2"	"3"	"2"	"2511"	"273.3"	"6.44"	"409.25"	"5.71"	"1"	"2"	"other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00107, Pf00109, Pf00550, Pf00698, Pf00975, Pf02801, Pf08242, Pf08659, Pf14765, Pf16197"	"2194"	"ENSG00000169710"	"FASN"	"hsa:2194; P49327; Q13479; Q16702; Q4LE83; Q6P4U5; Q6SS02; Q969R1; Q96C68; Q96IT0"	"AMP-activated protein kinase signaling; Sterol regulatory element-binding proteins (SREBP) signaling; SREBF and miR33 in cholesterol and lipid homeostasis; Liver X receptor pathway; Nuclear receptors meta-pathway; Fatty acid biosynthesis; Angiopoietin-like protein 8 regulatory pathway; Lipid metabolism pathway; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Omega-9 fatty acid synthesis; FOXA2 pathway"	"ChREBP activates metabolic gene expression; Activation of gene expression by SREBF (SREBP); Fatty acyl-CoA biosynthesis; NR1H2 & NR1H3 regulate gene expression linked to lipogenesis; Vitamin B5 (pantothenate) metabolism"	"18"	"0"	"7.9"	"4.6"	"9.8"	"8.5"	"5.5"	"7.5"	"8.3"	"17.8"	"15.0"	"22.9"	"50.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BWU0"	"Kanadaptin OS=Homo sapiens OX=9606 GN=SLC4A1AP PE=1 SV=1"	"0.000"	""	"4"	"3"	"5"	"3"	"796"	"88.8"	"5.19"	"1163.45"	"5.70"	"3"	"2"	""	"plasma membrane;other membranes;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00498"	"22950"	"ENSG00000163798"	"SLC4A1AP"	"A6NJ39; hsa:22950; Q4KMT1; Q4KMX0; Q7Z5Q9; Q9BWU0; Q9NVN2"	""	""	"0"	"0"	"108.7"	"98.3"	"121.9"	"104.4"	"104.2"	"111.2"	"163.3"	"218.5"	"184.8"	"581.1"	"1170.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11413"	"Glucose-6-phosphate 1-dehydrogenase OS=Homo sapiens OX=9606 GN=G6PD PE=1 SV=4"	"0.000"	""	"3"	"2"	"3"	"2"	"515"	"59.2"	"6.84"	"376.05"	"5.69"	"1"	"2"	"other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00479, Pf02781"	"2539"	"ENSG00000160211"	"G6PD"	"D3DWX9; hsa:2539; P11413; Q16000; Q16765; Q8IU70; Q8IU88; Q8IUA6; Q96PQ2"	"Glutathione metabolism; Pentose phosphate metabolism; Cori cycle; Vitamin D receptor pathway; Nuclear receptors meta-pathway; NRF2 pathway; ATM signaling in development and disease ; Metabolic reprogramming in colon cancer; Vitamin D-sensitive calcium signaling in depression; Pentose phosphate pathway in senescent cells; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Glycolysis in senescence; Sulfation biotransformation reaction"	"TP53 Regulates Metabolic Genes; NFE2L2 regulates pentose phosphate pathway genes; Pentose phosphate pathway"	"16"	"0"	"103.4"	"73.9"	"102.1"	"97.5"	"87.4"	"98.6"	"141.5"	"258.8"	"310.5"	"767.4"	"1384.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42695"	"Condensin-2 complex subunit D3 OS=Homo sapiens OX=9606 GN=NCAPD3 PE=1 SV=2"	"0.000"	""	"1"	"1"	"4"	"1"	"1498"	"168.8"	"7.50"	"582.58"	"5.69"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf12717"	"23310"	"ENSG00000151503"	"NCAPD3"	"A6NFS2; hsa:23310; P42695; Q4KMQ9"	""	"Condensation of Prophase Chromosomes"	"1"	"0"	"8.7"	"5.5"	"14.4"	"12.8"	"8.1"	"9.3"	"12.9"	"25.5"	"30.5"	"61.6"	"80.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H7B2"	"Ribosome production factor 2 homolog OS=Homo sapiens OX=9606 GN=RPF2 PE=1 SV=2"	"0.000"	""	"6"	"1"	"2"	"1"	"306"	"35.6"	"9.99"	"591.42"	"5.69"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf04427"	"84154"	"ENSG00000197498"	"RPF2"	"hsa:84154; Q5VXN1; Q8N4A1; Q9H7B2"	""	""	"0"	"0"	"52.9"	"27.5"	"56.8"	"47.9"	"55.8"	"55.2"	"62.2"	"89.4"	"100.5"	"180.0"	"260.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52815"	"39S ribosomal protein L12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL12 PE=1 SV=2"	"0.000"	""	"12"	"2"	"4"	"2"	"198"	"21.3"	"8.87"	"559.01"	"5.68"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00542, Pf16320"	"6182"	"ENSG00000262814"	"MRPL12"	"hsa:6182; P52815; Q969U0; Q9HCA2; Q9UQJ3"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"24.6"	"16.5"	"31.0"	"28.4"	"23.1"	"27.0"	"39.4"	"89.7"	"83.2"	"208.5"	"336.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P00390"	"Glutathione reductase, mitochondrial OS=Homo sapiens OX=9606 GN=GSR PE=1 SV=2"	"0.000"	""	"4"	"2"	"3"	"2"	"522"	"56.2"	"8.50"	"377.15"	"5.67"	"1"	"2"	"other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion"	"other molecular function"	"Pf00070, Pf02852"	"2936"	"ENSG00000104687"	"GSR"	"C8KIL8; C8KIL9; C8KIM0; D3DSV3; hsa:2936; P00390; Q7Z5C9; Q9NP63"	"Glutathione metabolism; Selenium micronutrient network; Trans-sulfuration, one-carbon metabolism and related pathways; Nuclear receptors meta-pathway; NRF2 pathway; Amino acid metabolism; Oxidative stress response; Vitamin D-sensitive calcium signaling in depression; Sulfation biotransformation reaction; Metapathway biotransformation Phase I and II"	""	"10"	"0"	"19.7"	"19.2"	"13.9"	"17.5"	"19.0"	"24.0"	"31.4"	"58.3"	"56.4"	"252.2"	"479.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15434"	"RNA-binding motif, single-stranded-interacting protein 2 OS=Homo sapiens OX=9606 GN=RBMS2 PE=1 SV=1"	"0.000"	""	"6"	"3"	"4"	"3"	"407"	"43.9"	"9.07"	"565.67"	"5.66"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"5939"	"ENSG00000076067"	"RBMS2"	"hsa:5939; Q15434"	""	""	"0"	"0"	"303.1"	"291.6"	"258.3"	"282.0"	"264.8"	"270.2"	"341.3"	"425.6"	"390.1"	"656.7"	"917.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99719"	"Septin-5 OS=Homo sapiens OX=9606 GN=SEPTIN5 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"369"	"42.8"	"6.67"	"504.43"	"5.65"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;transport;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf00735"	"5413"	"ENSG00000184702"	"SEPTIN5"	"hsa:5413; O15251; Q96MY5; Q99719"	"Parkin-ubiquitin proteasomal system pathway; Parkinson's disease pathway; 22q11.2 copy number variation syndrome"	""	"3"	"0"	"11.3"	"6.3"	"8.3"	"7.9"	"10.9"	"7.2"	"16.6"	"24.7"	"25.3"	"50.2"	"65.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4W6"	"AFG3-like protein 2 OS=Homo sapiens OX=9606 GN=AFG3L2 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"797"	"88.5"	"8.66"	"693.06"	"5.65"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf00004, Pf01434, Pf06480, Pf17862"	"10939"	"ENSG00000141385"	"AFG3L2"	"hsa:10939; Q6P1L0; Q9Y4W6"	"Ciliary landscape; 10q22q23 copy number variation"	"Processing of SMDT1"	"3"	"0"	"79.4"	"71.2"	"75.5"	"73.8"	"81.9"	"84.5"	"84.9"	"168.6"	"156.4"	"349.9"	"507.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HC35"	"Echinoderm microtubule-associated protein-like 4 OS=Homo sapiens OX=9606 GN=EML4 PE=1 SV=3"	"0.000"	""	"2"	"3"	"4"	"3"	"981"	"108.8"	"6.40"	"634.29"	"5.65"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400, Pf03451, Pf07714"	"27436"	"ENSG00000143924"	"EML4"	"A6H8Y6; A6P4T4; A6P4V4; B2RBK3; B2RTW7; B5MCW9; hsa:27436; Q3SWW0; Q53R29; Q53TW8; Q6PJ45; Q9HC35; Q9NV40"	"Non-small cell lung cancer"	"EML4 and NUDC in mitotic spindle formation; ALK mutants bind TKIs; Nuclear events stimulated by ALK signaling in cancer"	"5"	"0"	"182.1"	"159.8"	"156.1"	"154.4"	"166.4"	"164.5"	"194.5"	"438.2"	"384.6"	"1098.2"	"1449.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P26640"	"Valine--tRNA ligase OS=Homo sapiens OX=9606 GN=VARS1 PE=1 SV=4"	"0.000"	""	"2"	"3"	"5"	"3"	"1264"	"140.4"	"7.59"	"1278.42"	"5.64"	"3"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol"	"other molecular function"	"Pf00043, Pf00133, Pf08264"	"7407"	"ENSG00000096171; ENSG00000204394; ENSG00000224264; ENSG00000226589; ENSG00000231116"	"VARS1"	"B0V1N1; B4DZ61; hsa:7407; P26640; Q5JQ90; Q96E77; Q9UQM2"	"Amino acid metabolism"	"Cytosolic tRNA aminoacylation"	"2"	"0"	"293.7"	"268.2"	"292.7"	"272.4"	"258.8"	"269.6"	"333.8"	"386.1"	"379.5"	"575.9"	"841.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P60002"	"Transcription elongation factor 1 homolog OS=Homo sapiens OX=9606 GN=ELOF1 PE=1 SV=1"	""	""	"22"	"1"	"1"	"1"	"83"	"9.5"	"8.00"	""	"5.64"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf05129"	"84337"	"ENSG00000130165"	"ELOF1"	"hsa:84337; P60002; Q8R1J7; Q96II4"	""	""	"0"	"0"	"57.9"	"49.1"	"61.8"	"61.9"	"50.9"	"55.7"	"80.8"	"230.6"	"214.5"	"287.5"	"181.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5MNZ6"	"WD repeat domain phosphoinositide-interacting protein 3 OS=Homo sapiens OX=9606 GN=WDR45B PE=1 SV=2"	"0.000"	""	"9"	"2"	"4"	"2"	"344"	"38.1"	"7.59"	"724.23"	"5.63"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	""	"56270"	"ENSG00000141580"	"WDR45B"	"A0A024R8U4; A0A218N098; hsa:56270; O95328; Q2MCP6; Q5MNZ6; Q6IBN2"	""	"Macroautophagy"	"1"	"0"	"30.1"	"42.4"	"29.2"	"28.8"	"32.3"	"29.6"	"41.6"	"105.4"	"94.8"	"296.9"	"395.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q08378"	"Golgin subfamily A member 3 OS=Homo sapiens OX=9606 GN=GOLGA3 PE=1 SV=2"	"0.000"	""	"1"	"2"	"4"	"2"	"1498"	"167.3"	"5.44"	"565.01"	"5.63"	"2"	"2"	""	"other membranes;cytosol;ER/Golgi;nucleus"	""	""	"2802"	"ENSG00000090615"	"GOLGA3"	"A5PKX6; hsa:2802; O43241; Q08378; Q6P9C7; Q86XW3; Q8TDA9; Q8WZA3"	""	"RND2 GTPase cycle"	"1"	"0"	"11.5"	"8.7"	"16.1"	"13.3"	"9.4"	"14.3"	"16.9"	"59.6"	"55.1"	"127.1"	"155.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15369"	"Elongin-C OS=Homo sapiens OX=9606 GN=ELOC PE=1 SV=1"	"0.000"	""	"18"	"1"	"2"	"1"	"112"	"12.5"	"4.78"	"514.48"	"5.63"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf03931"	"6921"	"ENSG00000154582"	"ELOC"	"E5RGD9; hsa:6921; Q15369; Q567Q6"	"Dual hijack model of Vif in HIV infection; VEGFA-VEGFR2 signaling; Type 2 papillary renal cell carcinoma; Hijack of ubiquitination by SARS-CoV-2"	"Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; Antigen processing: Ubiquitination & Proteasome degradation; Regulation of expression of SLITs and ROBOs; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Vif-mediated degradation of APOBEC3G; Neddylation; Inactivation of CSF3 (G-CSF) signaling"	"21"	"0"	"18.3"	"14.5"	"21.8"	"19.0"	"21.8"	"20.0"	"21.0"	"48.9"	"49.8"	"103.7"	"136.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00139"	"Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3"	"0.000"	""	"4"	"3"	"5"	"3"	"706"	"79.9"	"6.68"	"909.62"	"5.61"	"3"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225"	"3796"	"ENSG00000068796"	"KIF2A"	"A5YM42; A5YM54; B4DY54; D3DW97; E9PB70; hsa:3796; O00139; Q7Z5I3; Q8N5Q7"	""	"COPI-dependent Golgi-to-ER retrograde traffic; Separation of Sister Chromatids; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Kinesins; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"9"	"0"	"265.4"	"210.1"	"238.0"	"257.0"	"229.0"	"245.0"	"305.7"	"339.0"	"320.4"	"544.9"	"738.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HD42"	"Charged multivesicular body protein 1a OS=Homo sapiens OX=9606 GN=CHMP1A PE=1 SV=1"	"0.000"	""	"8"	"2"	"4"	"2"	"196"	"21.7"	"8.06"	"646.68"	"5.61"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf03357"	"5119"	"ENSG00000131165"	"CHMP1A"	"A2RU09; hsa:5119; Q14468; Q15779; Q96G31; Q9HD42"	""	"HCMV Late Events"	"1"	"0"	"92.1"	"66.7"	"101.6"	"93.0"	"119.2"	"112.4"	"151.8"	"542.8"	"570.3"	"1875.3"	"2252.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BU02"	"Thiamine-triphosphatase OS=Homo sapiens OX=9606 GN=THTPA PE=1 SV=3"	"0.000"	""	"6"	"1"	"3"	"1"	"230"	"25.6"	"4.82"	"236.94"	"5.58"	"1"	"1"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf01928"	"79178"	"ENSG00000259431"	"THTPA"	"D3DS50; G3V4J3; hsa:79178; Q9BU02"	""	"Vitamin B1 (thiamin) metabolism"	"1"	"0"	"76.9"	"52.4"	"67.9"	"62.1"	"63.1"	"68.7"	"77.9"	"111.6"	"115.2"	"168.7"	"204.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9GZL7"	"Ribosome biogenesis protein WDR12 OS=Homo sapiens OX=9606 GN=WDR12 PE=1 SV=2"	"0.000"	""	"5"	"1"	"2"	"1"	"423"	"47.7"	"5.90"	"491.63"	"5.57"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00400, Pf08154"	"55759"	"ENSG00000138442"	"WDR12"	"B3KPA9; hsa:55759; Q96HU0; Q9GZL7; Q9NV80; Q9NYI8"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"29.7"	"34.4"	"36.1"	"37.2"	"35.3"	"42.6"	"51.9"	"73.7"	"75.7"	"171.5"	"341.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25789"	"Proteasome subunit alpha type-4 OS=Homo sapiens OX=9606 GN=PSMA4 PE=1 SV=1"	"0.000"	""	"6"	"2"	"4"	"2"	"261"	"29.5"	"7.72"	"684.92"	"5.56"	"2"	"2"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf00227, Pf10584"	"5685"	"ENSG00000041357"	"PSMA4"	"D3DW86; hsa:5685; P25789; Q53XP2; Q567Q5; Q8TBD1"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Exercise-induced circadian regulation; Alzheimer's disease"	"MAPK6/MAPK4 signaling; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"63"	"0"	"204.3"	"157.9"	"225.7"	"169.7"	"194.5"	"206.1"	"247.9"	"426.8"	"401.6"	"1111.2"	"2037.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08397"	"Porphobilinogen deaminase OS=Homo sapiens OX=9606 GN=HMBS PE=1 SV=2"	"0.000"	""	"6"	"1"	"2"	"1"	"361"	"39.3"	"7.18"	"545.05"	"5.56"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf01379, Pf03900"	"3145"	"ENSG00000256269"	"HMBS"	"A8K2L0; G3V1P4; G5EA58; hsa:3145; P08396; P08397; Q16012"	"Hemesynthesis defects and porphyrias; Heme biosynthesis"	"Heme biosynthesis"	"3"	"0"	"3.1"	"3.8"	"5.3"	"6.9"	"6.4"	"3.9"	"7.0"	"9.1"	"10.1"	"45.0"	"69.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9H0W5"	"Coiled-coil domain-containing protein 8 OS=Homo sapiens OX=9606 GN=CCDC8 PE=1 SV=2"	""	""	"4"	"1"	"1"	"1"	"538"	"59.3"	"8.63"	""	"5.55"	""	"1"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	""	"Pf14893"	"83987"	"ENSG00000169515"	"CCDC8"	"hsa:83987; Q8TB26; Q9H0W5"	""	"Neddylation"	"1"	"0"	"15.5"	"12.3"	"9.0"	"12.3"	"9.3"	"10.3"	"16.6"	"20.4"	"17.2"	"32.7"	"26.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BZ29"	"Dedicator of cytokinesis protein 9 OS=Homo sapiens OX=9606 GN=DOCK9 PE=1 SV=2"	"0.000"	""	"1"	"2"	"4"	"2"	"2069"	"236.3"	"7.49"	"660.11"	"5.55"	"2"	"2"	"signal transduction;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity"	"Pf00169, Pf06920, Pf11878, Pf14429, Pf20421, Pf20422"	"23348"	"ENSG00000088387"	"DOCK9"	"B3KX25; E9PFM9; hsa:23348; Q5JUD4; Q5JUD6; Q5T2Q1; Q5TAN8; Q9BZ25; Q9BZ26; Q9BZ27; Q9BZ28; Q9BZ29; Q9UPU4"	""	"CDC42 GTPase cycle; RAC1 GTPase cycle; Factors involved in megakaryocyte development and platelet production"	"3"	"0"	"38.2"	"26.7"	"30.0"	"40.2"	"53.5"	"157.7"	"267.7"	"241.9"	"149.5"	"128.7"	"157.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6A4"	"Cilia- and flagella-associated protein 20 OS=Homo sapiens OX=9606 GN=CFAP20 PE=1 SV=1"	"0.000"	""	"13"	"2"	"4"	"2"	"193"	"22.8"	"9.76"	"700.95"	"5.55"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	""	"Pf05018"	"29105"	"ENSG00000070761"	"CFAP20"	"hsa:29105; Q9Y6A4"	""	""	"0"	"0"	"87.7"	"86.3"	"76.7"	"75.5"	"72.5"	"77.9"	"90.1"	"142.1"	"146.1"	"276.5"	"408.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96L73"	"Histone-lysine N-methyltransferase, H3 lysine-36 specific OS=Homo sapiens OX=9606 GN=NSD1 PE=1 SV=1"	"0.000"	""	"1"	"2"	"4"	"2"	"2696"	"296.5"	"8.03"	"627.44"	"5.54"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00855, Pf00856, Pf17907, Pf17982"	"64324"	"ENSG00000165671"	"NSD1"	"hsa:64324; Q96L73; Q96PD8; Q96RN7"	"Histone modifications; Pathways affected in adenoid cystic carcinoma; 5q35 copy number variation"	"PKMTs methylate histone lysines"	"4"	"0"	"40.0"	"31.2"	"49.8"	"45.3"	"39.8"	"41.1"	"55.0"	"103.8"	"96.2"	"227.4"	"278.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P43487"	"Ran-specific GTPase-activating protein OS=Homo sapiens OX=9606 GN=RANBP1 PE=1 SV=1"	"0.000"	""	"11"	"2"	"4"	"2"	"201"	"23.3"	"5.29"	"652.09"	"5.53"	"2"	"2"	"transport;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00638"	"5902"	"ENSG00000099901"	"RANBP1"	"hsa:5902; P43487; Q53EY3"	"22q11.2 copy number variation syndrome"	"Rev-mediated nuclear export of HIV RNA"	"2"	"0"	"201.5"	"158.3"	"213.5"	"183.5"	"172.3"	"175.2"	"232.1"	"356.9"	"341.6"	"646.3"	"1275.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4A5"	"Transformation/transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3"	"0.000"	""	"1"	"2"	"4"	"2"	"3859"	"437.3"	"8.19"	"600.87"	"5.53"	"2"	"2"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00454, Pf02259, Pf20175, Pf20206"	"8295"	"ENSG00000196367"	"TRRAP"	"A4D265; hsa:8295; O75218; Q9Y4A5; Q9Y631; Q9Y6H4"	"Rett syndrome causing genes"	"Ub-specific processing proteases; HATs acetylate histones; Formation of the beta-catenin:TCF transactivating complex"	"4"	"0"	"56.6"	"55.8"	"63.7"	"65.9"	"63.5"	"71.2"	"70.8"	"150.9"	"140.4"	"352.6"	"457.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15006"	"ER membrane protein complex subunit 2 OS=Homo sapiens OX=9606 GN=EMC2 PE=1 SV=1"	"0.000"	""	"8"	"2"	"3"	"2"	"297"	"34.8"	"6.57"	"313.37"	"5.52"	"1"	"2"	"cell organization and biogenesis"	"other membranes;ER/Golgi;other cell component"	""	"Pf14559"	"9694"	"ENSG00000104412"	"EMC2"	"hsa:9694; Q15006; Q8WUE1"	""	""	"0"	"0"	"90.3"	"69.7"	"90.3"	"83.5"	"89.7"	"86.7"	"86.8"	"197.3"	"186.9"	"382.7"	"508.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00273"	"DNA fragmentation factor subunit alpha OS=Homo sapiens OX=9606 GN=DFFA PE=1 SV=1"	"0.000"	""	"6"	"2"	"3"	"2"	"331"	"36.5"	"4.79"	"245.77"	"5.50"	"1"	"2"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02017, Pf09033"	"1676"	"ENSG00000160049"	"DFFA"	"hsa:1676; O00273; Q5T6G5; Q5T6G6; Q96I97; Q9Y6C6"	"Apoptosis; Fas ligand pathway and stress induction of heat shock proteins; Acute viral myocarditis"	"Apoptosis induced DNA fragmentation"	"4"	"0"	"140.1"	"94.7"	"144.8"	"139.2"	"114.5"	"104.2"	"169.2"	"211.9"	"199.6"	"383.8"	"712.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H0S4"	"Probable ATP-dependent RNA helicase DDX47 OS=Homo sapiens OX=9606 GN=DDX47 PE=1 SV=1"	"0.000"	""	"8"	"2"	"3"	"2"	"455"	"50.6"	"9.10"	"1136.12"	"5.50"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes;signal transduction"	"nucleus"	"other molecular function"	"Pf00270, Pf00271"	"51202"	"ENSG00000213782"	"DDX47"	"B3KXP4; G5E955; hsa:51202; Q96GM0; Q96NV8; Q9H0S4; Q9UI98"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"73.7"	"86.5"	"88.8"	"76.3"	"71.6"	"74.6"	"101.7"	"124.8"	"112.2"	"213.5"	"280.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2X0"	"Mediator of RNA polymerase II transcription subunit 16 OS=Homo sapiens OX=9606 GN=MED16 PE=1 SV=2"	"0.000"	""	"2"	"2"	"3"	"2"	"877"	"96.7"	"7.37"	"278.38"	"5.50"	"1"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf11635"	"10025"	"ENSG00000175221"	"MED16"	"hsa:10025; Q6PJT2; Q96AD4; Q96I35; Q9Y2X0; Q9Y652"	""	"PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; Generic Transcription Pathway"	"3"	"0"	"16.6"	"5.4"	"23.0"	"20.5"	"18.5"	"15.5"	"22.9"	"44.5"	"58.1"	"117.9"	"148.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63220"	"40S ribosomal protein S21 OS=Homo sapiens OX=9606 GN=RPS21 PE=1 SV=1"	"0.000"	""	"23"	"2"	"4"	"2"	"83"	"9.1"	"8.50"	"622.22"	"5.48"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01249"	"6227"	"ENSG00000171858"	"RPS21"	"hsa:6227; P35265; P63220"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"337.0"	"271.9"	"386.9"	"360.6"	"348.8"	"335.9"	"476.9"	"701.5"	"600.1"	"1001.7"	"1315.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5HYJ3"	"Protein FAM76B OS=Homo sapiens OX=9606 GN=FAM76B PE=1 SV=3"	"0.000"	""	"6"	"2"	"3"	"2"	"339"	"38.7"	"9.25"	"367.13"	"5.48"	"1"	"2"	""	"nucleus"	""	"Pf16046"	"143684"	"ENSG00000077458"	"FAM76B"	"B2R9C2; hsa:143684; Q5HYJ3; Q6PIU3; Q8TC53"	""	""	"0"	"0"	"140.0"	"128.9"	"143.8"	"143.8"	"135.9"	"109.8"	"187.7"	"336.7"	"313.3"	"450.3"	"513.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92522"	"Histone H1.10 OS=Homo sapiens OX=9606 GN=H1-10 PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"213"	"22.5"	"10.76"	"575.25"	"5.48"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00538"	"8971"	"ENSG00000184897"	"H1-10"	"hsa:8971; Q92522"	""	""	"0"	"0"	"45.1"	"48.9"	"42.6"	"39.6"	"44.4"	"41.9"	"49.9"	"62.3"	"55.9"	"101.5"	"145.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75874"	"Isocitrate dehydrogenase [NADP] cytoplasmic OS=Homo sapiens OX=9606 GN=IDH1 PE=1 SV=2"	"0.000"	""	"4"	"2"	"4"	"2"	"414"	"46.6"	"7.01"	"605.68"	"5.48"	"2"	"2"	"other metabolic processes;stress response;developmental processes;other biological processes"	"non-structural extracellular;cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00180"	"3417"	"ENSG00000138413"	"IDH1"	"hsa:3417; O75874; Q567U4; Q6FHQ6; Q7Z3V0; Q93090; Q9NTJ9; Q9UKW8"	"Glutathione metabolism; TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism"	"Peroxisomal protein import; Neutrophil degranulation; Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate; NADPH regeneration; NFE2L2 regulating TCA cycle genes"	"8"	"0"	"60.1"	"50.9"	"72.9"	"58.7"	"55.0"	"52.5"	"80.1"	"123.8"	"117.5"	"400.3"	"842.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94874"	"E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2"	"0.000"	""	"4"	"2"	"3"	"2"	"794"	"89.5"	"6.79"	"273.71"	"5.47"	"1"	"2"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf09743"	"23376"	"ENSG00000014123"	"UFL1"	"A0PJ53; B4DJ57; C0H5X5; hsa:23376; O94874; Q8N765; Q9NTQ0"	""	"Antigen processing: Ubiquitination & Proteasome degradation"	"1"	"0"	"106.2"	"67.5"	"111.4"	"91.3"	"90.4"	"95.7"	"137.0"	"243.3"	"224.5"	"439.7"	"489.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q02040"	"A-kinase anchor protein 17A OS=Homo sapiens OX=9606 GN=AKAP17A PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"695"	"80.7"	"9.73"	"609.34"	"5.46"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus"	"other molecular function"	""	"8227"	"ENSG00000197976"	"AKAP17A"	"hsa:8227; Q02040; Q02832; Q2TB98; Q5JQ74; Q5JQ76; Q8N6U9"	""	""	"0"	"0"	"79.6"	"52.2"	"102.2"	"69.8"	"71.5"	"73.1"	"103.8"	"320.7"	"297.2"	"610.8"	"833.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BZF9"	"Uveal autoantigen with coiled-coil domains and ankyrin repeats OS=Homo sapiens OX=9606 GN=UACA PE=1 SV=2"	"0.000"	""	"1"	"2"	"4"	"1"	"1416"	"162.4"	"7.03"	"613.24"	"5.46"	"2"	"2"	"other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus"	"cytoskeletal activity"	"Pf12796"	"55075"	"ENSG00000137831"	"UACA"	"G3XAG2; hsa:55075; Q14DD3; Q8N3B8; Q96NH6; Q9BZF9; Q9HCL1; Q9NWC6"	""	"Regulation of the apoptosome activity; RHOH GTPase cycle"	"2"	"0"	"28.7"	"18.5"	"27.7"	"26.8"	"26.9"	"33.2"	"53.2"	"157.0"	"146.9"	"275.6"	"277.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95983"	"Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1"	"0.000"	""	"12"	"3"	"6"	"2"	"291"	"32.8"	"5.34"	"1919.85"	"5.46"	"3"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01429, Pf14048, Pf16564"	"53615"	"ENSG00000071655"	"MBD3"	"A8K4B7; D6W5Z2; hsa:53615; O95983; Q6PIL9; Q6PJZ9; Q86XF4"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"Potential therapeutics for SARS; HDACs deacetylate histones; Regulation of PTEN gene transcription; RNA Polymerase I Transcription Initiation; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of TP53 Activity through Acetylation"	"7"	"1"	"378.1"	"290.6"	"304.9"	"296.2"	"283.1"	"297.3"	"380.5"	"527.3"	"516.6"	"1032.1"	"1484.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKA9"	"Polypyrimidine tract-binding protein 2 OS=Homo sapiens OX=9606 GN=PTBP2 PE=1 SV=1"	"0.000"	""	"7"	"3"	"5"	"2"	"531"	"57.5"	"8.66"	"1308.88"	"5.45"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf11835, Pf13893"	"58155"	"ENSG00000117569"	"PTBP2"	"hsa:58155; Q8N0Z1; Q8N160; Q8NFB0; Q8NFB1; Q969N9; Q96Q76; Q9UKA9"	"Genes targeted by miRNAs in adipocytes; mRNA processing"	""	"2"	"0"	"98.7"	"96.5"	"109.2"	"91.9"	"113.2"	"106.0"	"149.5"	"277.3"	"301.2"	"792.3"	"1144.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P53680"	"AP-2 complex subunit sigma OS=Homo sapiens OX=9606 GN=AP2S1 PE=1 SV=2"	"0.000"	""	"18"	"3"	"5"	"3"	"142"	"17.0"	"6.18"	"755.26"	"5.45"	"3"	"2"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01217"	"1175"	"ENSG00000042753"	"AP2S1"	"B2R4Z4; hsa:1175; O75977; P53680; Q6PK67"	"Synaptic vesicle pathway; VEGFA-VEGFR2 signaling; GABA receptor signaling; EGF/EGFR signaling pathway; Fragile X syndrome"	"Cargo recognition for clathrin-mediated endocytosis; LDL clearance; Recycling pathway of L1; MHC class II antigen presentation; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; Retrograde neurotrophin signalling; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; VLDLR internalisation and degradation; Potential therapeutics for SARS; Nef Mediated CD4 Down-regulation; Nef Mediated CD8 Down-regulation"	"18"	"0"	"122.1"	"91.6"	"143.0"	"132.3"	"129.1"	"241.4"	"417.1"	"906.7"	"843.9"	"1051.7"	"1095.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62277"	"40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2"	"0.000"	""	"32"	"5"	"6"	"5"	"151"	"17.2"	"10.54"	"1415.63"	"5.44"	"4"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00312, Pf08069"	"6207"	"ENSG00000110700"	"RPS13"	"B2R549; hsa:6207; P19116; P62277; Q02546; Q29200; Q498Y0"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"629.1"	"531.7"	"611.2"	"527.1"	"539.7"	"551.2"	"766.8"	"1058.6"	"1030.9"	"2191.8"	"3095.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WWH5"	"Probable tRNA pseudouridine synthase 1 OS=Homo sapiens OX=9606 GN=TRUB1 PE=1 SV=1"	"0.000"	""	"6"	"2"	"4"	"2"	"349"	"37.2"	"8.25"	"651.18"	"5.44"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01509"	"142940"	"ENSG00000165832"	"TRUB1"	"B2R716; hsa:142940; Q53ES2; Q8WWH5"	""	""	"0"	"0"	"57.2"	"45.5"	"50.5"	"55.1"	"59.2"	"49.0"	"76.1"	"129.6"	"133.4"	"468.8"	"685.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96CS3"	"FAS-associated factor 2 OS=Homo sapiens OX=9606 GN=FAF2 PE=1 SV=2"	"0.000"	""	"6"	"2"	"4"	"2"	"445"	"52.6"	"5.62"	"534.66"	"5.44"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport"	"non-structural extracellular;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00789, Pf14555"	"23197"	"ENSG00000113194"	"FAF2"	"hsa:23197; O94963; Q8IUF2; Q96CS3; Q9BRP2; Q9BVM7"	"5q35 copy number variation"	"Neutrophil degranulation; RHOA GTPase cycle"	"3"	"0"	"48.4"	"37.9"	"66.0"	"53.5"	"46.3"	"47.0"	"70.0"	"208.3"	"199.0"	"664.9"	"1047.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42765"	"3-ketoacyl-CoA thiolase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAA2 PE=1 SV=2"	"0.000"	""	"4"	"2"	"4"	"2"	"397"	"41.9"	"8.09"	"635.38"	"5.44"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;stress response;transport"	"mitochondrion"	"other molecular function"	"Pf00108, Pf02803"	"10449"	"ENSG00000167315"	"ACAA2"	"hsa:10449; P42765; Q9BUT6"	"Fatty acid biosynthesis"	"Mitochondrial Fatty Acid Beta-Oxidation"	"2"	"0"	"97.4"	"73.1"	"92.0"	"78.7"	"109.5"	"75.2"	"117.0"	"326.8"	"368.5"	"1146.3"	"1615.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43670"	"BUB3-interacting and GLEBS motif-containing protein ZNF207 OS=Homo sapiens OX=9606 GN=ZNF207 PE=1 SV=1"	"0.000"	""	"4"	"2"	"4"	"2"	"478"	"50.7"	"9.10"	"673.62"	"5.42"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	""	"7756"	"ENSG00000010244"	"ZNF207"	"A8K6Y6; E1P660; E1P661; E1P662; hsa:7756; O43670; Q53XS9; Q96HW5; Q9BUQ7"	""	""	"0"	"0"	"306.1"	"223.1"	"292.5"	"281.8"	"353.5"	"290.8"	"425.9"	"663.3"	"655.0"	"1016.3"	"1144.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NW13"	"RNA-binding protein 28 OS=Homo sapiens OX=9606 GN=RBM28 PE=1 SV=3"	"0.000"	""	"2"	"2"	"4"	"2"	"759"	"85.7"	"9.22"	"605.09"	"5.42"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf00076"	"55131"	"ENSG00000106344"	"RBM28"	"A4D100; B4DU52; E9PDD9; hsa:55131; Q53H65; Q96CV3; Q9NW13"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"274.4"	"219.0"	"331.2"	"287.7"	"289.1"	"256.3"	"348.8"	"614.5"	"627.2"	"978.2"	"1273.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96F85"	"CB1 cannabinoid receptor-interacting protein 1 OS=Homo sapiens OX=9606 GN=CNRIP1 PE=1 SV=1"	""	""	"14"	"1"	"1"	"1"	"164"	"18.6"	"7.94"	""	"5.42"	""	"1"	"other biological processes"	"plasma membrane;other membranes;other cell component"	"signal transduction activity or receptor binding"	"Pf15043"	"25927"	"ENSG00000119865"	"CNRIP1"	"B2R4D0; hsa:25927; Q49AN4; Q96F85; Q9UFZ0"	""	""	"0"	"0"	"4.2"	"2.7"	"5.6"	"2.0"	"6.9"	"13.1"	"16.1"	"34.0"	"32.3"	"48.6"	"56.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12929"	"Epidermal growth factor receptor kinase substrate 8 OS=Homo sapiens OX=9606 GN=EPS8 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"822"	"91.8"	"7.50"	"619.66"	"5.42"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00018, Pf08416, Pf18016"	"2059"	"ENSG00000151491"	"EPS8"	"A6NMC3; A8K6W2; A8KA66; B4DX66; hsa:2059; Q12929; Q8N6J0"	"EGF/EGFR signaling pathway; IL-18 signaling pathway"	"Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea"	"4"	"0"	"52.0"	"22.4"	"65.0"	"57.4"	"50.4"	"55.6"	"71.0"	"60.7"	"61.5"	"78.2"	"85.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L2J0"	"7SK snRNA methylphosphate capping enzyme OS=Homo sapiens OX=9606 GN=MEPCE PE=1 SV=1"	"0.000"	""	"4"	"2"	"4"	"2"	"689"	"74.3"	"9.57"	"553.99"	"5.42"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06859, Pf13847"	"56257"	"ENSG00000146834"	"MEPCE"	"B3KP86; D6W5V7; hsa:56257; Q7L2J0; Q9NPD4"	"IL-18 signaling pathway; 1p36 copy number variation syndrome"	""	"2"	"0"	"40.1"	"22.4"	"49.6"	"47.8"	"42.1"	"45.0"	"52.4"	"94.2"	"84.4"	"183.7"	"243.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14174"	"Macrophage migration inhibitory factor OS=Homo sapiens OX=9606 GN=MIF PE=1 SV=4"	"0.000"	""	"8"	"1"	"4"	"1"	"115"	"12.5"	"7.88"	"643.55"	"5.42"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;stress response;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01187"	"4282"	"ENSG00000240972; ENSG00000276701"	"MIF"	"A5Z1R8; B2R4S3; hsa:4282; P14174; Q2V4Y5; Q6FHV0"	"Adipogenesis; Spinal cord injury"	"Neutrophil degranulation; Cell surface interactions at the vascular wall; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	"5"	"0"	"240.7"	"150.6"	"284.9"	"244.7"	"237.0"	"226.4"	"363.7"	"464.7"	"389.3"	"642.5"	"993.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61254"	"60S ribosomal protein L26 OS=Homo sapiens OX=9606 GN=RPL26 PE=1 SV=1"	"0.000"	""	"12"	"2"	"4"	"2"	"145"	"17.2"	"10.55"	"613.05"	"5.38"	"2"	"2"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00467, Pf16906"	"6154"	"ENSG00000161970"	"RPL26"	"B2R4F0; D3DTR8; hsa:6154; P61254; Q02877; Q6IPY2"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Peptide chain elongation; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"15"	"0"	"337.4"	"304.6"	"349.4"	"320.8"	"312.9"	"330.0"	"435.9"	"593.1"	"520.5"	"1013.1"	"1415.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14671"	"Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1186"	"126.4"	"6.84"	"459.61"	"5.36"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00806"	"9698"	"ENSG00000134644"	"PUM1"	"A8K6W4; B4DG92; D3DPN3; E9PCJ0; hsa:9698; Q14671; Q53HH5; Q5VXY7; Q9HAN1"	""	"Golgi Associated Vesicle Biogenesis"	"1"	"0"	"31.0"	"38.8"	"33.3"	"35.7"	"38.6"	"35.9"	"39.4"	"68.2"	"56.5"	"95.7"	"111.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95104"	"SR-related and CTD-associated factor 4 OS=Homo sapiens OX=9606 GN=SCAF4 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1147"	"125.8"	"9.55"	"365.76"	"5.36"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf04818"	"57466"	"ENSG00000156304"	"SCAF4"	"C9JLZ0; hsa:57466; O95104; Q0P5W8; Q6P1M5; Q8N3I8; Q9UFM1; Q9ULP8"	""	""	"0"	"0"	"25.7"	"18.0"	"30.4"	"32.5"	"24.1"	"32.5"	"33.9"	"42.3"	"44.4"	"96.7"	"113.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P61077"	"Ubiquitin-conjugating enzyme E2 D3 OS=Homo sapiens OX=9606 GN=UBE2D3 PE=1 SV=1"	""	""	"16"	"1"	"1"	"1"	"147"	"16.7"	"7.80"	""	"5.36"	""	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00179"	"7323"	"ENSG00000109332"	"UBE2D3"	"A6NJ93; A6NJB1; A6NM99; hsa:7323; P47986; P61077; Q6IB88; Q6NXS4; Q8N924"	"Proteasome degradation"	"Peroxisomal protein import; Antigen processing: Ubiquitination & Proteasome degradation; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Neddylation; E3 ubiquitin ligases ubiquitinate target proteins; IKK complex recruitment mediated by RIP1; Signaling by BMP; Inactivation of CSF3 (G-CSF) signaling; TICAM1, RIP1-mediated IKK complex recruitment; Regulation of TNFR1 signaling; Negative regulators of DDX58/IFIH1 signaling; Downregulation of SMAD2/3:SMAD4 transcriptional activity"	"13"	"0"	"9.9"	"6.0"	"16.9"	"13.3"	"18.7"	"14.2"	"18.5"	"24.4"	"21.7"	"57.5"	"79.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P48634"	"Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3"	"0.000"	""	"2"	"2"	"2"	"2"	"2157"	"228.7"	"9.45"	"397.70"	"5.35"	"1"	"1"	"other biological processes"	"plasma membrane;other membranes;cytosol;nucleus"	""	"Pf07001"	"7916"	"ENSG00000204469; ENSG00000206427; ENSG00000225164; ENSG00000225748; ENSG00000226618; ENSG00000231370; ENSG00000231825"	"PRRC2A"	"B0UX77; B0UZE9; B0UZL3; hsa:7916; O95875; P48634; Q05BK4; Q4LE37; Q5SQ29; Q5SQ30; Q5ST84; Q5STX6; Q5STX7; Q68DW9; Q6P9P7; Q6PIN1; Q8MGQ9; Q96QC6"	""	""	"0"	"0"	"58.3"	"67.7"	"55.0"	"49.2"	"54.0"	"58.9"	"81.0"	"113.4"	"112.7"	"203.7"	"269.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96RT1"	"Erbin OS=Homo sapiens OX=9606 GN=ERBIN PE=1 SV=2"	"0.000"	""	"2"	"2"	"4"	"2"	"1412"	"158.2"	"5.50"	"610.10"	"5.35"	"2"	"2"	"cell adhesion;cell organization and biogenesis;transport;signal transduction;other biological processes"	"extracellular matrix;plasma membrane;other membranes;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity"	"Pf00595, Pf13855"	"55914"	"ENSG00000112851"	"ERBIN"	"A0AVR1; B4E3F1; B7ZLV9; E7EQW9; E9PCR8; hsa:55914; Q1RMD0; Q86W38; Q96RT1; Q9NR18; Q9NW48; Q9ULJ5"	"Nucleotide-binding oligomerization domain (NOD) pathway; Nod-like receptor (NLR) signaling pathway; Pathways affected in adenoid cystic carcinoma"	"RHOC GTPase cycle; RHOA GTPase cycle; RHOB GTPase cycle; RAC1 GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; Downregulation of ERBB2 signaling; Signaling by ERBB2 KD Mutants; Signaling by ERBB2 TMD/JMD mutants; Signaling by ERBB2 ECD mutants; Constitutive Signaling by Overexpressed ERBB2; Drug-mediated inhibition of ERBB2 signaling; Resistance of ERBB2 KD mutants to trastuzumab; Resistance of ERBB2 KD mutants to sapitinib; Resistance of ERBB2 KD mutants to tesevatinib; Resistance of ERBB2 KD mutants to neratinib; Resistance of ERBB2 KD mutants to osimertinib; Resistance of ERBB2 KD mutants to afatinib; Resistance of ERBB2 KD mutants to AEE788; Resistance of ERBB2 KD mutants to lapatinib; Drug resistance in ERBB2 TMD/JMD mutants"	"26"	"0"	"9.3"	"5.7"	"13.8"	"9.8"	"10.8"	"10.5"	"11.8"	"33.3"	"29.2"	"74.2"	"106.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q76FK4"	"Nucleolar protein 8 OS=Homo sapiens OX=9606 GN=NOL8 PE=1 SV=1"	"0.000"	""	"2"	"2"	"4"	"2"	"1167"	"131.5"	"7.09"	"632.19"	"5.35"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf00076"	"55035"	"ENSG00000198000"	"NOL8"	"hsa:55035; Q5TCC7; Q5TCC8; Q5TCD3; Q5TCD5; Q5TCD6; Q5TCD7; Q76D35; Q76FK4; Q7L3E2; Q9H586; Q9H795; Q9H7W7; Q9H9J6; Q9NWA4; Q9NWM4"	""	""	"0"	"0"	"13.6"	"11.0"	"14.0"	"11.4"	"13.8"	"11.4"	"21.1"	"32.1"	"28.7"	"45.4"	"48.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49458"	"Signal recognition particle 9 kDa protein OS=Homo sapiens OX=9606 GN=SRP9 PE=1 SV=2"	"0.000"	""	"22"	"2"	"4"	"2"	"86"	"10.1"	"7.97"	"596.58"	"5.34"	"2"	"2"	"transport;other biological processes"	"other membranes;cytosol;ER/Golgi;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf05486"	"6726"	"ENSG00000143742"	"SRP9"	"A8K0N0; hsa:6726; P49458; Q6NVX0; Q8WTW0"	""	"SRP-dependent cotranslational protein targeting to membrane"	"1"	"0"	"159.9"	"123.7"	"122.9"	"133.4"	"134.2"	"140.4"	"218.7"	"440.9"	"378.7"	"640.6"	"1037.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86SX6"	"Glutaredoxin-related protein 5, mitochondrial OS=Homo sapiens OX=9606 GN=GLRX5 PE=1 SV=2"	"0.000"	""	"11"	"2"	"4"	"2"	"157"	"16.6"	"6.79"	"605.57"	"5.33"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00462"	"51218"	"ENSG00000182512"	"GLRX5"	"hsa:51218; Q0X088; Q3YML0; Q86SX6; Q86WY3; Q8IZ54"	"Iron-sulfur cluster biogenesis"	"Mitochondrial iron-sulfur cluster biogenesis"	"2"	"0"	"14.1"	"12.4"	"11.1"	"10.1"	"13.1"	"14.6"	"13.9"	"23.2"	"14.3"	"38.3"	"40.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50213"	"Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3A PE=1 SV=1"	"0.000"	""	"5"	"2"	"4"	"2"	"366"	"39.6"	"6.92"	"556.51"	"5.32"	"2"	"2"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00180"	"3419"	"ENSG00000166411"	"IDH3A"	"D3DW83; hsa:3419; P50213; Q9H3X0"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Metabolic reprogramming in colon cancer; TCA cycle (aka Krebs or citric acid cycle)"	"Citric acid cycle (TCA cycle)"	"4"	"0"	"59.3"	"52.0"	"53.2"	"60.7"	"55.7"	"60.8"	"58.2"	"116.2"	"90.0"	"444.6"	"870.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IXS8"	"Protein FAM126B OS=Homo sapiens OX=9606 GN=FAM126B PE=1 SV=1"	"0.000"	""	"4"	"2"	"3"	"2"	"530"	"58.6"	"7.90"	"299.35"	"5.32"	"1"	"2"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol"	""	"Pf09790"	"285172"	"ENSG00000155744"	"HYCC2"	"B2RCG7; hsa:285172; Q4ZG87; Q53TX6; Q8IXS8"	""	""	"0"	"0"	"41.4"	"25.5"	"40.8"	"42.2"	"33.9"	"33.5"	"48.1"	"89.4"	"102.1"	"280.5"	"355.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NEY8"	"Periphilin-1 OS=Homo sapiens OX=9606 GN=PPHLN1 PE=1 SV=2"	"0.000"	""	"3"	"2"	"5"	"2"	"458"	"52.7"	"9.11"	"933.73"	"5.31"	"2"	"1"	"cell organization and biogenesis;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	""	"Pf11488"	"51535"	"ENSG00000134283"	"PPHLN1"	"E9PAX8; hsa:51535; Q86YT2; Q8IXN3; Q8NEY8; Q8TB09; Q96NB9; Q9NXL4; Q9P0P6; Q9P0R9"	""	""	"0"	"0"	"750.3"	"666.5"	"701.0"	"696.5"	"617.5"	"632.8"	"828.1"	"1026.3"	"910.2"	"1669.4"	"2253.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IWF6"	"Protein DENND6A OS=Homo sapiens OX=9606 GN=DENND6A PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"608"	"69.5"	"8.27"	"584.78"	"5.30"	"1"	"1"	"other biological processes"	"cytosol;other cytoplasmic organelle;other cell component"	"enzyme regulator activity"	"Pf08616, Pf09794"	"201627"	"ENSG00000174839"	"DENND6A"	"hsa:201627; Q7Z5T4; Q8IWF6; Q8N235; Q8TEG8"	""	"RAB GEFs exchange GTP for GDP on RABs"	"1"	"0"	"30.4"	"28.3"	"22.2"	"27.1"	"26.9"	"28.3"	"32.5"	"44.5"	"40.0"	"70.2"	"83.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BTL3"	"RNA guanine-N7 methyltransferase activating subunit OS=Homo sapiens OX=9606 GN=RAMAC PE=1 SV=1"	"0.000"	""	"19"	"2"	"3"	"2"	"118"	"14.4"	"8.94"	"934.86"	"5.30"	"2"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf15320"	"83640"	"ENSG00000169612"	"RAMAC"	"hsa:83640; Q2M1J8; Q9BTL3"	"15q25 copy number variation"	""	"1"	"0"	"194.8"	"147.0"	"240.9"	"181.6"	"181.5"	"172.2"	"206.8"	"364.3"	"365.0"	"642.0"	"786.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50750"	"Cyclin-dependent kinase 9 OS=Homo sapiens OX=9606 GN=CDK9 PE=1 SV=3"	"0.000"	""	"6"	"3"	"4"	"2"	"372"	"42.8"	"8.79"	"563.41"	"5.29"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00069"	"1025"	"ENSG00000136807"	"CDK9"	"hsa:1025; P50750; Q5JU24; Q5JU25; Q5U006; Q96TF1"	"MicroRNAs in cardiomyocyte hypertrophy; IL-9 signaling pathway; Cardiac hypertrophic response; Initiation of transcription and translation elongation at the HIV-1 LTR; Male infertility"	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; Estrogen-dependent gene expression; Interactions of Tat with host cellular proteins"	"20"	"0"	"164.5"	"139.1"	"150.8"	"155.5"	"139.0"	"136.7"	"193.4"	"306.7"	"324.5"	"547.1"	"692.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4P3"	"Transducin beta-like protein 2 OS=Homo sapiens OX=9606 GN=TBL2 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"447"	"49.8"	"9.44"	"546.39"	"5.28"	"1"	"1"	"stress response;signal transduction"	"other membranes;ER/Golgi"	"other molecular function"	"Pf00400"	"26608"	"ENSG00000106638"	"TBL2"	"hsa:26608; Q9UQE2; Q9Y4P3"	"7q11.23 copy number variation syndrome"	""	"1"	"0"	"32.8"	"14.5"	"40.3"	"33.5"	"37.8"	"27.3"	"33.4"	"64.9"	"69.4"	"170.6"	"198.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BWT3"	"Poly(A) polymerase gamma OS=Homo sapiens OX=9606 GN=PAPOLG PE=1 SV=2"	"0.000"	""	"2"	"2"	"4"	"1"	"736"	"82.8"	"9.14"	"538.72"	"5.26"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01909, Pf04926, Pf04928"	"64895"	"ENSG00000115421"	"PAPOLG"	"B2RBH4; hsa:64895; Q59G05; Q969N1; Q9BWT3; Q9H8L2; Q9HAD0"	""	""	"0"	"0"	"13.0"	"8.8"	"12.1"	"16.4"	"11.7"	"17.5"	"18.0"	"35.2"	"48.6"	"87.0"	"103.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60684"	"Importin subunit alpha-7 OS=Homo sapiens OX=9606 GN=KPNA6 PE=1 SV=1"	"0.000"	""	"5"	"3"	"5"	"1"	"536"	"60.0"	"4.98"	"903.17"	"5.26"	"3"	"2"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00514, Pf01749, Pf16186"	"23633"	"ENSG00000025800"	"KPNA6"	"B2RDC7; D3DPP5; hsa:23633; O60684; Q5VVU3"	""	"Assembly of the ORC complex at the origin of replication"	"1"	"1"	"262.2"	"220.0"	"260.0"	"224.2"	"219.6"	"251.2"	"300.3"	"459.6"	"472.1"	"1281.8"	"1960.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9GZN1"	"Actin-related protein 6 OS=Homo sapiens OX=9606 GN=ACTR6 PE=1 SV=1"	""	""	"6"	"1"	"1"	"1"	"396"	"45.8"	"5.03"	""	"5.24"	""	"1"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00022"	"64431"	"ENSG00000075089"	"ACTR6"	"B3KW37; B4DLG9; hsa:64431; Q53GH2; Q9BY39; Q9GZN1; Q9H8H6"	""	""	"0"	"0"	"9.8"	"7.3"	"12.4"	"10.5"	"10.7"	"10.4"	"17.1"	"45.9"	"60.0"	"209.8"	"264.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P48739"	"Phosphatidylinositol transfer protein beta isoform OS=Homo sapiens OX=9606 GN=PITPNB PE=1 SV=2"	""	""	"9"	"1"	"1"	"1"	"271"	"31.5"	"6.87"	""	"5.23"	""	"1"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;ER/Golgi;other cell component"	"transporter activity;other molecular function"	"Pf02121"	"23760"	"ENSG00000180957"	"PITPNB"	"B3KYB8; B7Z7Q0; hsa:23760; P48739; Q8N5W1"	""	"PI and PC transport between ER and Golgi membranes"	"1"	"0"	"14.0"	"13.6"	"14.1"	"6.6"	"15.1"	"9.2"	"14.0"	"23.0"	"21.2"	"38.3"	"63.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q04206"	"Transcription factor p65 OS=Homo sapiens OX=9606 GN=RELA PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"551"	"60.2"	"5.68"	""	"5.23"	""	"1"	"cell-cell signaling;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00554, Pf16179"	"5970"	"ENSG00000173039"	"RELA"	"hsa:5970; Q04206; Q6GTV1; Q6SLK1"	"Androgen receptor signaling pathway; Nucleotide-binding oligomerization domain (NOD) pathway; Osteopontin signaling; Selenium micronutrient network; Vitamin B12 metabolism; Folate metabolism; IL-1 signaling pathway; RANKL/RANK signaling pathway; Leptin signaling pathway; TNF-related weak inducer of apoptosis (TWEAK) signaling pathway; Prolactin signaling pathway; Alzheimer's disease and miRNA effects; IL-17 signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; B cell receptor signaling pathway; AGE/RAGE pathway; Interleukin-11 signaling pathway; Corticotropin-releasing hormone signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Apoptosis; Aryl hydrocarbon receptor pathway; Ebstein-Barr virus LMP1 signaling; Interleukin-1 (IL-1) structural pathway; Nod-like receptor (NLR) signaling pathway; RAC1/PAK1/p38/MMP2 pathway; Initiation of transcription and translation elongation at the HIV-1 LTR; Photodynamic therapy-induced NF-kB survival signaling; MAPK signaling pathway; Toll-like receptor signaling related to MyD88; Novel intracellular components of RIG-I-like receptor pathway; VEGFA-VEGFR2 signaling; ApoE and miR-146 in inflammation and atherosclerosis; Chemokine signaling pathway; IL-4 signaling pathway; NO/cGMP/PKG mediated neuroprotection; Fibrin complement receptor 3 signaling pathway; PI3K/AKT/mTOR - vitamin D3 signaling; PI3K-Akt signaling pathway; Ebola virus infection in host; Ras signaling; Pancreatic adenocarcinoma pathway; miRNA role in immune response in sepsis; ncRNAs involved in STAT3 signaling in hepatocellular carcinoma; Nonalcoholic fatty liver disease; Supression of HMGB1 mediated inflammation by THBD; Altered glycosylation of MUC1 in tumor microenvironment; Resistin as a regulator of inflammation; Vitamin D in inflammatory diseases; Signal transduction through IL1R; Canonical NF-kB pathway; Measles virus infection; Cytosolic DNA-sensing pathway; Small cell lung cancer; Gastrin signaling pathway; Hepatitis B infection; Head and neck squamous cell carcinoma; IL-18 signaling pathway; CAMKK2 pathway; Activation of NLRP3 inflammasome by SARS-CoV-2; Neuroinflammation; STING pathway in Kawasaki-like disease and COVID-19; Modulators of TCR signaling and T cell activation; Opioid receptor pathways; CCL18 signaling pathway; Antiviral and anti-inflammatory effects of Nrf2 on SARS-CoV-2 pathway; Alzheimer's disease; GDNF signaling; IL-26 signaling pathways; A network map of Macrophage-stimulating protein (MSP) signaling; Role of hypoxia, angiogenesis, and FGF pathway in OA chondrocyte hypertrophy; 15q11q13 copy number variation; T-cell receptor signaling pathway; Toll-like receptor signaling pathway"	"Senescence-Associated Secretory Phenotype (SASP); FCERI mediated NF-kB activation; Downstream TCR signaling; Transcriptional regulation of white adipocyte differentiation; Activation of NF-kappaB in B cells; Dectin-1 mediated noncanonical NF-kB signaling; Transcriptional Regulation by VENTX; PKMTs methylate histone lysines; RIP-mediated NFkB activation via ZBP1; NF-kB is activated and signals survival; TAK1-dependent IKK and NF-kappa-B activation  ; IkBA variant leads to EDA-ID; TRAF6 mediated NF-kB activation; The NLRP3 inflammasome; Purinergic signaling in leishmaniasis infection; SARS-CoV-1 activates/modulates innate immune responses; CD209 (DC-SIGN) signaling; Interleukin-1 processing; CLEC7A/inflammasome pathway; Regulated proteolysis of p75NTR; DEx/H-box helicases activate type I IFN and inflammatory cytokines production ; SUMOylation of immune response proteins"	"98"	"0"	"20.8"	"15.7"	"22.2"	"25.1"	"20.9"	"18.8"	"30.0"	"54.4"	"42.5"	"86.0"	"102.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6UWE0"	"E3 ubiquitin-protein ligase LRSAM1 OS=Homo sapiens OX=9606 GN=LRSAM1 PE=1 SV=1"	"0.000"	""	"3"	"2"	"3"	"2"	"723"	"83.5"	"5.94"	"304.18"	"5.23"	"1"	"2"	"protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;other cell component"	"other molecular function"	"Pf07647, Pf13855, Pf13920"	"90678"	"ENSG00000148356"	"LRSAM1"	"hsa:90678; Q5VVV0; Q6UWE0; Q8NB40; Q96GT5; Q96MX5; Q96MZ7"	"Intracellular trafficking proteins involved in CMT neuropathy"	"Antigen processing: Ubiquitination & Proteasome degradation"	"2"	"0"	"23.9"	"20.8"	"29.2"	"24.9"	"22.6"	"26.8"	"33.6"	"72.4"	"64.0"	"180.0"	"269.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UER7"	"Death domain-associated protein 6 OS=Homo sapiens OX=9606 GN=DAXX PE=1 SV=2"	"0.001"	""	"3"	"2"	"3"	"2"	"740"	"81.3"	"4.87"	"231.44"	"5.21"	"1"	"2"	"cell organization and biogenesis;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf03344"	"1616"	"ENSG00000204209; ENSG00000206206; ENSG00000206279; ENSG00000227046; ENSG00000231617"	"DAXX"	"B4E1I3; F5ANJ6; F5ANJ7; F5H082; hsa:1616; O14747; O15141; O15208; Q5STK9; Q9BWI3; Q9UER7"	"Androgen receptor signaling pathway; Amyotrophic lateral sclerosis (ALS); Fas ligand pathway and stress induction of heat shock proteins; MAPK signaling pathway; p38 MAPK signaling pathway"	"HCMV Early Events; SUMOylation of transcription cofactors; Inhibition of DNA recombination at telomere; Regulation of TP53 Degradation; Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations; Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations"	"11"	"0"	"23.2"	"19.9"	"28.2"	"29.0"	"26.0"	"25.1"	"40.3"	"59.9"	"52.4"	"130.2"	"160.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96RL1"	"BRCA1-A complex subunit RAP80 OS=Homo sapiens OX=9606 GN=UIMC1 PE=1 SV=2"	"0.000"	""	"4"	"2"	"3"	"2"	"719"	"79.7"	"5.45"	"715.67"	"5.19"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf18282"	"51720"	"ENSG00000087206"	"UIMC1"	"A8MSA1; B3KMZ1; B4E3N2; hsa:51720; Q5XKQ1; Q7Z3W7; Q8N5B9; Q96RL1; Q9BZR1; Q9BZR5; Q9UHX7"	"5q35 copy number variation"	"Processing of DNA double-strand break ends; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; G2/M DNA damage checkpoint; Nonhomologous End-Joining (NHEJ); Metalloprotease DUBs"	"6"	"0"	"331.4"	"219.6"	"329.2"	"316.3"	"295.6"	"298.0"	"376.2"	"495.7"	"504.7"	"727.5"	"853.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P20618"	"Proteasome subunit beta type-1 OS=Homo sapiens OX=9606 GN=PSMB1 PE=1 SV=2"	"0.000"	""	"8"	"1"	"2"	"1"	"241"	"26.5"	"8.13"	"378.09"	"5.18"	"1"	"1"	"protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	""	"Pf00227"	"5689"	"ENSG00000008018"	"PSMB1"	"B5BU76; hsa:5689; P20618; Q9BWA8"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Neutrophil degranulation; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; MAPK6/MAPK4 signaling; The role of GTSE1 in G2/M progression after G2 checkpoint; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"63"	"0"	"21.7"	"18.3"	"32.2"	"32.1"	"18.1"	"25.8"	"36.5"	"55.0"	"39.8"	"115.5"	"221.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96KP1"	"Exocyst complex component 2 OS=Homo sapiens OX=9606 GN=EXOC2 PE=1 SV=1"	"0.000"	""	"3"	"2"	"5"	"2"	"924"	"104.0"	"6.90"	"1010.16"	"5.17"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf01833, Pf15469"	"55770"	"ENSG00000112685"	"EXOC2"	"B2RBE6; hsa:55770; Q5JPC8; Q96AN6; Q96KP1; Q9NUZ8; Q9UJM7"	"RalA downstream regulated genes; Chromosomal and microsatellite instability in colorectal cancer ; Ras signaling; Ciliary landscape"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"7"	"0"	"0.0"	"0.0"	"0.0"	"1.9"	"0.0"	"0.0"	"0.0"	"18.1"	"24.9"	"35.3"	"46.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P59998"	"Actin-related protein 2/3 complex subunit 4 OS=Homo sapiens OX=9606 GN=ARPC4 PE=1 SV=3"	"0.000"	""	"10"	"2"	"4"	"2"	"168"	"19.7"	"8.43"	"617.86"	"5.17"	"2"	"2"	"cell organization and biogenesis"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf05856"	"10093"	"ENSG00000241553"	"ARPC4"	"C9JWM7; E7ETI0; F6TTL5; hsa:10093; O15509; P59998; Q6P0W5; Q96QJ3"	"Pathogenic Escherichia coli infection"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Clathrin-mediated endocytosis; EPHB-mediated forward signaling"	"6"	"0"	"110.8"	"65.2"	"91.0"	"92.3"	"79.6"	"95.1"	"125.4"	"454.4"	"590.3"	"1399.7"	"1885.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q07889"	"Son of sevenless homolog 1 OS=Homo sapiens OX=9606 GN=SOS1 PE=1 SV=1"	"0.000"	""	"2"	"2"	"4"	"2"	"1333"	"152.4"	"6.84"	"692.32"	"5.15"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00169, Pf00617, Pf00618, Pf00621"	"6654"	"ENSG00000115904"	"SOS1"	"A8K2G3; B4DXG2; hsa:6654; Q07889"	"IL-5 signaling pathway; Integrin-mediated cell adhesion; Leptin signaling pathway; Prolactin signaling pathway; Pilocytic astrocytoma; Androgen receptor network in prostate cancer; B cell receptor signaling pathway; TNF-alpha signaling pathway; Oncostatin M signaling pathway; Alpha 6 beta 4 signaling pathway; IL-3 signaling pathway; Kit receptor signaling pathway; Focal adhesion; Hepatocyte growth factor receptor signaling; RAC1/PAK1/p38/MMP2 pathway; IL6 signaling pathway; Hepatitis C and hepatocellular carcinoma; BDNF-TrkB signaling; Physico-chemical features and toxicity-associated pathways; MAPK signaling pathway; T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection; Angiopoietin-like protein 8 regulatory pathway; Chemokine signaling pathway; Embryonic stem cell pluripotency pathways; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; IL-4 signaling pathway; Endometrial cancer; PI3K-Akt signaling pathway; MAPK cascade; Ras signaling; Epithelial to mesenchymal transition in colorectal cancer; Non-small cell lung cancer; Breast cancer pathway; Acute viral myocarditis; Thermogenesis; EGF/EGFR signaling pathway; Envelope proteins and their potential roles in EDMD physiopathology; Fragile X syndrome; Gastrin signaling pathway; Hepatitis B infection; Melanoma; Thyroid hormones production and peripheral downstream signaling effects; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; IL-2 signaling pathway; MAPK pathway in congenital thyroid cancer; Pleural mesothelioma; Regulation of actin cytoskeleton; 4p16.3 copy number variation; 5q35 copy number variation; EPO receptor signaling; ErbB signaling pathway; T-cell receptor signaling pathway; DNA damage response (only ATM dependent)"	"Role of LAT2/NTAL/LAB on calcium mobilization; RET signaling; Downstream signal transduction; Tie2 Signaling; Signaling by CSF1 (M-CSF) in myeloid cells; FRS-mediated FGFR1 signaling; FRS-mediated FGFR2 signaling; FRS-mediated FGFR3 signaling; FRS-mediated FGFR4 signaling; FLT3 Signaling; Activated NTRK2 signals through FRS2 and FRS3; Signaling by FLT3 ITD and TKD mutants; FCERI mediated MAPK activation; FCERI mediated Ca+2 mobilization; Potential therapeutics for SARS; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; RAC1 GTPase cycle; NRAGE signals death through JNK; G alpha (12/13) signalling events; Interleukin receptor SHC signaling; RAF/MAP kinase cascade; DAP12 signaling; Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants; Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants; Signaling by PDGFRA extracellular domain mutants; Regulation of KIT signaling; SHC1 events in ERBB2 signaling; SHC1 events in ERBB4 signaling; GRB2 events in ERBB2 signaling; Signaling by ERBB2 KD Mutants; Signaling by ERBB2 TMD/JMD mutants; GRB2 events in EGFR signaling; SHC1 events in EGFR signaling; NCAM signaling for neurite out-growth; Signaling by FGFR1 in disease; SHC-mediated cascade:FGFR1; SHC-mediated cascade:FGFR2; Signaling by FGFR2 in disease; SHC-mediated cascade:FGFR3; SHC-mediated cascade:FGFR4; Signaling by FGFR3 in disease; Activation of RAC1; Erythropoietin activates RAS; Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; EGFR Transactivation by Gastrin; Constitutive Signaling by EGFRvIII; Signaling by ERBB2 ECD mutants; SOS-mediated signalling; Signalling to RAS; SHC-related events triggered by IGF1R; Signaling by FGFR4 in disease; MET activates RAS signaling; Activated NTRK2 signals through RAS; Activated NTRK3 signals through RAS; Constitutive Signaling by Overexpressed ERBB2; Signaling by FLT3 fusion proteins; Signal attenuation; GRB2:SOS provides linkage to MAPK signaling for Integrins ; Interleukin-15 signaling"	"115"	"0"	"22.4"	"15.8"	"20.6"	"23.9"	"25.9"	"23.8"	"50.9"	"172.5"	"153.3"	"403.5"	"542.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61024"	"Cyclin-dependent kinases regulatory subunit 1 OS=Homo sapiens OX=9606 GN=CKS1B PE=1 SV=1"	"0.000"	""	"20"	"1"	"2"	"1"	"79"	"9.7"	"8.94"	"636.21"	"5.14"	"1"	"1"	"cell cycle OR cell proliferation;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf01111"	"1163"	"ENSG00000173207"	"CKS1B"	"hsa:1163; P33551; P61024"	"Small cell lung cancer"	"SCF(Skp2)-mediated degradation of p27/p21; Cyclin D associated events in G1"	"3"	"0"	"31.6"	"41.6"	"24.1"	"19.6"	"19.7"	"27.7"	"31.4"	"107.5"	"131.8"	"373.2"	"759.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00116"	"Alkyldihydroxyacetonephosphate synthase, peroxisomal OS=Homo sapiens OX=9606 GN=AGPS PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"658"	"72.9"	"7.34"	"555.78"	"5.14"	"1"	"1"	"other metabolic processes"	"cytosol;other cytoplasmic organelle"	"other molecular function"	"Pf01565, Pf02913"	"8540"	"ENSG00000018510"	"AGPS"	"A5D8U9; hsa:8540; O00116; Q2TU35"	"Triacylglyceride synthesis"	"Plasmalogen biosynthesis; TYSND1 cleaves peroxisomal proteins"	"4"	"0"	"70.1"	"45.7"	"68.4"	"63.2"	"58.8"	"54.8"	"80.9"	"102.8"	"116.5"	"153.0"	"133.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3A3"	"MOB-like protein phocein OS=Homo sapiens OX=9606 GN=MOB4 PE=1 SV=1"	"0.000"	""	"13"	"3"	"5"	"3"	"225"	"26.0"	"5.78"	"1034.61"	"5.13"	"3"	"2"	""	"other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf03637"	"25843"	"ENSG00000115540"	"MOB4"	"B4DML0; hsa:25843; Q53SE0; Q7Z4Y6; Q9H2P3; Q9H5J1; Q9Y3A3; Q9Y4T8"	""	""	"0"	"0"	"144.7"	"119.3"	"137.6"	"124.8"	"111.3"	"124.8"	"154.9"	"259.9"	"271.2"	"694.4"	"876.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q02224"	"Centromere-associated protein E OS=Homo sapiens OX=9606 GN=CENPE PE=1 SV=2"	"0.000"	""	"1"	"2"	"3"	"1"	"2701"	"316.2"	"5.64"	"288.39"	"5.12"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225"	"1062"	"ENSG00000138778"	"CENPE"	"A6NKY9; A8K2U7; hsa:1062; Q02224; Q4LE75"	"Regulation of sister chromatid separation at the metaphase-anaphase transition"	"RHO GTPases Activate Formins; COPI-dependent Golgi-to-ER retrograde traffic; Separation of Sister Chromatids; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; EML4 and NUDC in mitotic spindle formation; Kinesins; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"10"	"0"	"8.9"	"4.5"	"3.9"	"7.4"	"4.6"	"6.3"	"8.1"	"15.9"	"15.4"	"31.5"	"37.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51114"	"Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3"	"0.000"	""	"3"	"2"	"4"	"1"	"621"	"69.7"	"6.15"	"618.28"	"5.12"	"2"	"2"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf05641, Pf12235, Pf16096, Pf16097, Pf17904, Pf18336"	"8087"	"ENSG00000114416"	"FXR1"	"A8K9B8; hsa:8087; P51114; Q7Z450; Q8N6R8"	"Bile acids synthesis and enterohepatic circulation"	"Signaling by BRAF and RAF1 fusions"	"2"	"0"	"124.4"	"94.3"	"114.5"	"115.9"	"121.6"	"110.0"	"143.6"	"211.6"	"212.9"	"495.8"	"601.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WYQ5"	"Microprocessor complex subunit DGCR8 OS=Homo sapiens OX=9606 GN=DGCR8 PE=1 SV=1"	"0.000"	""	"3"	"2"	"3"	"2"	"773"	"86.0"	"5.95"	"315.32"	"5.12"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00035"	"54487"	"ENSG00000128191"	"DGCR8"	"B2R8G1; hsa:54487; Q6DCB2; Q6MZE9; Q6Y2L0; Q8WYQ5; Q96G39; Q96GP8; Q9H6L8; Q9H6T7; Q9NRW2"	"miRNA biogenesis; exRNA mechanism of action and biogenesis; DDX1 as a regulatory component of the Drosha microprocessor; 22q11.2 copy number variation syndrome"	"Transcriptional Regulation by MECP2; MicroRNA (miRNA) biogenesis"	"6"	"0"	"31.4"	"26.3"	"29.0"	"31.1"	"28.6"	"34.7"	"44.5"	"69.5"	"61.6"	"111.8"	"146.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y2Q9"	"28S ribosomal protein S28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS28 PE=1 SV=1"	""	""	"13"	"1"	"1"	"1"	"187"	"20.8"	"9.10"	""	"5.11"	""	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	""	"Pf10246"	"28957"	"ENSG00000147586"	"MRPS28"	"B2RDZ7; hsa:28957; Q96Q21; Q9Y2Q9"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"23.4"	"24.0"	"40.9"	"22.0"	"21.4"	"22.5"	"39.9"	"56.5"	"56.1"	"114.6"	"147.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q13884"	"Beta-1-syntrophin OS=Homo sapiens OX=9606 GN=SNTB1 PE=1 SV=3"	""	""	"4"	"1"	"1"	"1"	"538"	"58.0"	"8.63"	""	"5.11"	""	"1"	"other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00169, Pf00595, Pf18012"	"6641"	"ENSG00000172164"	"SNTB1"	"A8K9E0; hsa:6641; O14912; Q13884; Q4KMG8"	"IL-18 signaling pathway; 13q12.12 copy number variation"	""	"2"	"0"	"17.9"	"13.7"	"17.3"	"15.3"	"12.6"	"9.6"	"14.0"	"25.8"	"24.3"	"46.8"	"63.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9C037"	"E3 ubiquitin-protein ligase TRIM4 OS=Homo sapiens OX=9606 GN=TRIM4 PE=1 SV=2"	""	""	"2"	"1"	"4"	"1"	"500"	"57.4"	"8.10"	""	"5.11"	""	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00622, Pf00643, Pf15227"	"89122"	"ENSG00000146833"	"TRIM4"	"A4D298; hsa:89122; Q75MK1; Q96F06; Q9C036; Q9C037"	""	"Antigen processing: Ubiquitination & Proteasome degradation; SARS-CoV-2 activates/modulates innate and adaptive immune responses; TRAF6 mediated NF-kB activation; NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10; Negative regulators of DDX58/IFIH1 signaling; Ovarian tumor domain proteases; TRAF3-dependent IRF activation pathway; TRAF6 mediated IRF7 activation"	"9"	"0"	"265.5"	"212.2"	"154.1"	"161.1"	"134.2"	"172.5"	"263.1"	"638.1"	"721.5"	"2094.8"	"3189.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y512"	"Sorting and assembly machinery component 50 homolog OS=Homo sapiens OX=9606 GN=SAMM50 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"469"	"51.9"	"6.90"	"531.29"	"5.10"	"1"	"1"	"cell organization and biogenesis;transport"	"other membranes;mitochondrion"	""	"Pf01103"	"25813"	"ENSG00000100347"	"SAMM50"	"hsa:25813; Q53HC4; Q56VW7; Q969Y9; Q96I46; Q9NW85; Q9UQM9; Q9Y512"	""	"RAC2 GTPase cycle; Mitochondrial protein import; Cristae formation"	"3"	"0"	"46.7"	"30.2"	"43.3"	"55.9"	"43.6"	"40.2"	"66.3"	"176.2"	"225.5"	"569.1"	"861.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3X0"	"Coiled-coil domain-containing protein 9 OS=Homo sapiens OX=9606 GN=CCDC9 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"531"	"59.7"	"5.40"	"609.32"	"5.10"	"1"	"1"	""	"nucleus"	"nucleic acid binding activity"	"Pf15266"	"26093"	"ENSG00000105321"	"CCDC9"	"hsa:26093; Q9Y3X0"	"IL-18 signaling pathway"	""	"1"	"0"	"9.7"	"7.7"	"11.7"	"7.2"	"6.6"	"7.4"	"12.3"	"13.9"	"14.1"	"29.3"	"49.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NRL2"	"Bromodomain adjacent to zinc finger domain protein 1A OS=Homo sapiens OX=9606 GN=BAZ1A PE=1 SV=2"	"0.000"	""	"2"	"3"	"5"	"3"	"1556"	"178.6"	"6.60"	"927.26"	"5.09"	"3"	"2"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00439, Pf00628, Pf02791, Pf10537, Pf15612, Pf15613"	"11177"	"ENSG00000198604"	"BAZ1A"	"hsa:11177; Q9NRL2; Q9NZ15; Q9P065; Q9UIG1; Q9Y3V3"	"Ectoderm differentiation"	""	"1"	"0"	"73.6"	"61.2"	"78.6"	"67.4"	"81.1"	"73.6"	"95.3"	"195.1"	"189.4"	"485.1"	"554.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VZE5"	"N-alpha-acetyltransferase 35, NatC auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA35 PE=1 SV=1"	"0.000"	""	"3"	"2"	"4"	"2"	"725"	"83.6"	"7.05"	"530.95"	"5.09"	"2"	"2"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	""	"Pf04112"	"60560"	"ENSG00000135040"	"NAA35"	"hsa:60560; Q5VZE5; Q5VZE6; Q9H631; Q9H703"	""	"Retrograde transport at the Trans-Golgi-Network"	"1"	"0"	"0.0"	"0.0"	"7.3"	"0.0"	"2.4"	"4.2"	"4.9"	"21.4"	"22.3"	"51.7"	"61.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95819"	"Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens OX=9606 GN=MAP4K4 PE=1 SV=2"	"0.000"	""	"2"	"2"	"4"	"1"	"1239"	"142.0"	"7.46"	"530.44"	"5.08"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"other cell component"	"cytoskeletal activity;kinase activity;other molecular function"	"Pf00069, Pf00780"	"9448"	"ENSG00000071054"	"MAP4K4"	"E7ESS2; hsa:9448; O75172; O95819; Q9NST7"	"MAPK signaling pathway; Angiopoietin-like protein 8 regulatory pathway; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-YAP signaling; Insulin signaling; Pleural mesothelioma"	"Oxidative Stress Induced Senescence"	"7"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P06400"	"Retinoblastoma-associated protein OS=Homo sapiens OX=9606 GN=RB1 PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"928"	"106.1"	"7.94"	""	"5.08"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01857, Pf01858, Pf08934, Pf11934"	"5925"	"ENSG00000139687"	"RB1"	"A8K5E3; hsa:5925; P06400; P78499; Q5VW46; Q8IZL4"	"Androgen receptor signaling pathway; miRNA regulation of DNA damage response; Cell cycle; Thyroid stimulating hormone (TSH) signaling pathway; Glioblastoma signaling pathways; Adipogenesis; Spinal cord injury; Retinoblastoma gene in cancer; Aryl hydrocarbon receptor pathway; Bladder cancer; Fas ligand pathway and stress induction of heat shock proteins; H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity; Tumor suppressor activity of SMARCB1; Non-small cell lung cancer; Breast cancer pathway; Pancreatic adenocarcinoma pathway; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; Ciliary landscape; G1 to S cell cycle control; Small cell lung cancer; Head and neck squamous cell carcinoma; Melanoma; Overlap between signal transduction pathways contributing to LMNA laminopathies; 7q11.23 copy number variation syndrome; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Glycolysis in senescence; Sphingolipid metabolism in senescence; Prostaglandin and leukotriene metabolism in senescence ; ID signaling pathway; TROP2 regulatory signaling; Prostaglandin and leukotriene metabolism in senescence ; DNA damage response"	"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Oncogene Induced Senescence; Cyclin D associated events in G1; Defective binding of RB1 mutants to E2F1,(E2F2, E2F3); Aberrant regulation of mitotic exit in cancer due to RB1 defects; RUNX2 regulates osteoblast differentiation; Condensation of Prophase Chromosomes; Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes; Cyclin A:Cdk2-associated events at S phase entry; Formation of Senescence-Associated Heterochromatin Foci (SAHF); Inhibition of replication initiation of damaged DNA by RB1/E2F1; Defective translocation of RB1 mutants to the nucleus; Replication of the SARS-CoV-1 genome; Replication of the SARS-CoV-2 genome"	"47"	"0"	"26.1"	"13.1"	"31.2"	"27.1"	"28.5"	"29.3"	"28.3"	"55.2"	"51.8"	"100.2"	"115.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BQC6"	"Ribosomal protein 63, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL57 PE=1 SV=1"	"0.000"	""	"13"	"1"	"2"	"1"	"102"	"12.3"	"11.44"	"500.38"	"5.07"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf14978"	"78988"	"ENSG00000173141"	"MRPL57"	"A2A332; hsa:78988; Q9BQC6"	""	"Mitochondrial translation elongation; Mitochondrial translation initiation; Mitochondrial translation termination"	"3"	"0"	"53.6"	"47.4"	"62.8"	"60.3"	"56.1"	"54.9"	"79.5"	"125.5"	"115.6"	"244.8"	"403.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62879"	"Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 OS=Homo sapiens OX=9606 GN=GNB2 PE=1 SV=3"	"0.000"	""	"5"	"1"	"2"	"1"	"340"	"37.3"	"6.00"	"414.17"	"5.07"	"1"	"1"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00400"	"2783"	"ENSG00000172354"	"GNB2"	"B3KPU1; hsa:2783; P11016; P54312; P62879"	"Corticotropin-releasing hormone signaling pathway; Myometrial relaxation and contraction pathways; G protein signaling pathways; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Ras signaling; Calcium regulation in cardiac cells"	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; G alpha (12/13) signalling events; G alpha (q) signalling events; G alpha (i) signalling events; G alpha (z) signalling events; ADP signalling through P2Y purinoceptor 12; Extra-nuclear estrogen signaling; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production; Thrombin signalling through proteinase activated receptors (PARs); Activation of G protein gated Potassium channels; G-protein activation; G beta:gamma signalling through PI3Kgamma; Prostacyclin signalling through prostacyclin receptor; Adrenaline,noradrenaline inhibits insulin secretion; Ca2+ pathway; G beta:gamma signalling through PLC beta; ADP signalling through P2Y purinoceptor 1; Glucagon-type ligand receptors; Thromboxane signalling through TP receptor; Vasopressin regulates renal water homeostasis via Aquaporins; Presynaptic function of Kainate receptors; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; G beta:gamma signalling through BTK; G beta:gamma signalling through CDC42; Inhibition  of voltage gated Ca2+ channels via Gbeta/gamma subunits; Glucagon signaling in metabolic regulation"	"36"	"0"	"14.6"	"10.7"	"18.5"	"16.2"	"17.7"	"19.6"	"20.8"	"38.5"	"46.0"	"141.5"	"269.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVR2"	"Integrator complex subunit 10 OS=Homo sapiens OX=9606 GN=INTS10 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"710"	"82.2"	"7.44"	"629.47"	"5.07"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	""	"55174"	"ENSG00000104613"	"INTS10"	"hsa:55174; Q6IA93; Q7L538; Q7L8C8; Q9H3W8; Q9NVR2"	"1p36 copy number variation syndrome"	"RNA polymerase II transcribes snRNA genes"	"2"	"0"	"77.6"	"64.8"	"80.9"	"83.7"	"78.1"	"61.7"	"99.3"	"195.0"	"182.7"	"487.3"	"694.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P10644"	"cAMP-dependent protein kinase type I-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR1A PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"381"	"43.0"	"5.35"	"443.11"	"5.06"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00027, Pf02197"	"5573"	"ENSG00000108946"	"PRKAR1A"	"hsa:5573; K7ER48; P10644; Q567S7"	"Mesodermal commitment pathway; Myometrial relaxation and contraction pathways; Mesodermal commitment pathway; G protein signaling pathways; Cannabinoid receptor signaling; Lipid metabolism pathway; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; Fragile X syndrome; Cardiomyocyte signaling pathways converging on Titin; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"FCGR3A-mediated IL10 synthesis; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production; ALK mutants bind TKIs; Signaling by ALK fusions and activated point mutants; Factors involved in megakaryocyte development and platelet production; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Vasopressin regulates renal water homeostasis via Aquaporins; PKA activation; PKA activation in glucagon signalling; Hedgehog 'off' state; DARPP-32 events; CREB1 phosphorylation through the activation of Adenylate Cyclase"	"25"	"0"	"32.5"	"22.4"	"29.8"	"36.2"	"27.8"	"34.1"	"41.8"	"71.1"	"67.2"	"151.0"	"228.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H2K8"	"Serine/threonine-protein kinase TAO3 OS=Homo sapiens OX=9606 GN=TAOK3 PE=1 SV=2"	"0.000"	""	"3"	"3"	"5"	"2"	"898"	"105.3"	"7.30"	"888.85"	"5.06"	"3"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069"	"51347"	"ENSG00000135090"	"TAOK3"	"hsa:51347; Q658N1; Q8IUM4; Q9H2K8; Q9HC79; Q9NZM9; Q9UHG7"	"MAPK signaling pathway"	"RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle"	"4"	"0"	"29.1"	"14.3"	"26.8"	"21.8"	"33.0"	"43.1"	"72.0"	"137.3"	"121.3"	"132.9"	"121.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WXC6"	"COP9 signalosome complex subunit 9 OS=Homo sapiens OX=9606 GN=COPS9 PE=1 SV=3"	"0.000"	""	"35"	"1"	"2"	"1"	"57"	"6.2"	"3.83"	"466.08"	"5.06"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	""	"Pf15004"	"150678"	"ENSG00000172428"	"COPS9"	"hsa:150678; Q8N110; Q8WXC6"	"2q37 copy number variation syndrome"	""	"1"	"0"	"6.0"	"2.2"	"1.6"	"2.5"	"4.0"	"8.1"	"10.5"	"17.3"	"21.1"	"46.9"	"79.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q01968"	"Inositol polyphosphate 5-phosphatase OCRL OS=Homo sapiens OX=9606 GN=OCRL PE=1 SV=3"	"0.000"	""	"4"	"2"	"3"	"2"	"901"	"104.1"	"6.55"	"341.51"	"5.05"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00620, Pf03372, Pf16726"	"4952"	"ENSG00000122126"	"OCRL"	"A6NKI1; A8KAP2; B7ZLX2; hsa:4952; O60800; Q01968; Q15684; Q15774; Q4VY09; Q4VY10; Q5JQF1; Q5JQF2; Q9UJG5; Q9UMA5"	"VEGFA-VEGFR2 signaling; Ciliopathies; Bardet-Biedl syndrome"	"Clathrin-mediated endocytosis; RAC3 GTPase cycle; RHOJ GTPase cycle; Golgi Associated Vesicle Biogenesis; Synthesis of PIPs at the plasma membrane; Synthesis of PIPs at the Golgi membrane; Synthesis of IP2, IP, and Ins in the cytosol; Synthesis of IP3 and IP4 in the cytosol"	"11"	"0"	"11.4"	"4.7"	"9.9"	"10.1"	"13.9"	"15.2"	"12.4"	"30.2"	"32.3"	"73.5"	"111.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H6E4"	"Coiled-coil domain-containing protein 134 OS=Homo sapiens OX=9606 GN=CCDC134 PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"229"	"26.5"	"8.85"	"557.29"	"5.05"	"1"	"1"	"developmental processes;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;nucleus;other cell component"	""	"Pf15002"	"79879"	"ENSG00000100147"	"CCDC134"	"hsa:79879; Q9H6E4"	""	""	"0"	"0"	"28.3"	"22.0"	"26.0"	"26.2"	"35.0"	"27.8"	"44.1"	"97.4"	"101.5"	"182.9"	"231.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92734"	"Protein TFG OS=Homo sapiens OX=9606 GN=TFG PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"400"	"43.4"	"5.10"	"461.40"	"5.04"	"1"	"1"	"cell organization and biogenesis;transport"	"cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00564"	"10342"	"ENSG00000114354"	"TFG"	"D3DN49; G5E9V1; hsa:10342; K0J5S8; K0J6K2; Q15656; Q92734; Q969I2"	""	"Signaling by ALK fusions and activated point mutants; COPII-mediated vesicle transport"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99633"	"Pre-mRNA-splicing factor 18 OS=Homo sapiens OX=9606 GN=PRPF18 PE=1 SV=1"	"0.000"	""	"9"	"3"	"5"	"3"	"342"	"39.8"	"8.15"	"1194.01"	"5.04"	"3"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf02840, Pf08799"	"8559"	"ENSG00000165630"	"PRPF18"	"hsa:8559; Q5T9P9; Q99633; Q9BUI9"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"298.7"	"212.0"	"315.4"	"263.7"	"247.9"	"307.0"	"449.8"	"769.7"	"587.3"	"651.6"	"747.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9H008"	"Phospholysine phosphohistidine inorganic pyrophosphate phosphatase OS=Homo sapiens OX=9606 GN=LHPP PE=1 SV=2"	""	""	"8"	"1"	"1"	"1"	"270"	"29.1"	"6.15"	""	"5.03"	""	"1"	"other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf13242, Pf13344"	"64077"	"ENSG00000107902"	"LHPP"	"B3KP20; hsa:64077; Q2TBE9; Q5VUV9; Q5VUW0; Q9H008"	""	"Pyrophosphate hydrolysis"	"1"	"0"	"9.0"	"8.1"	"14.8"	"14.1"	"12.5"	"11.2"	"20.3"	"28.7"	"32.2"	"94.2"	"125.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15599"	"Na(+)/H(+) exchange regulatory cofactor NHE-RF2 OS=Homo sapiens OX=9606 GN=SLC9A3R2 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"337"	"37.4"	"7.93"	"672.14"	"5.03"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00595, Pf09007"	"9351"	"ENSG00000065054"	"NHERF2"	"D3DU84; D3DU85; H3BSV6; hsa:9351; O00272; O00556; Q15599; Q3KQY7"	""	""	"0"	"0"	"39.5"	"39.0"	"26.3"	"47.2"	"34.7"	"35.3"	"36.8"	"37.0"	"30.8"	"47.8"	"52.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75175"	"CCR4-NOT transcription complex subunit 3 OS=Homo sapiens OX=9606 GN=CNOT3 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"753"	"81.8"	"6.20"	"611.75"	"5.02"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf04065, Pf04153"	"4849"	"ENSG00000088038; ENSG00000273943; ENSG00000274176; ENSG00000274616; ENSG00000274941; ENSG00000275979; ENSG00000276082; ENSG00000277114; ENSG00000277600; ENSG00000277615"	"CNOT3"	"hsa:4849; O75175; Q9NZN7; Q9UF76"	""	"Deadenylation of mRNA; TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"	"2"	"0"	"32.4"	"13.3"	"36.1"	"29.0"	"26.6"	"29.2"	"44.9"	"96.4"	"101.1"	"332.6"	"706.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6Y7W6"	"GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1299"	"150.0"	"5.54"	"570.33"	"5.02"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf02213"	"26058"	"ENSG00000204120"	"GIGYF2"	"A6H8W4; B9EG55; E9PBB0; hsa:26058; O75137; Q6Y7W6; Q7Z2Z8; Q7Z3I2; Q96HU4; Q9NV82"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"46.3"	"42.8"	"44.6"	"41.7"	"43.0"	"47.2"	"54.6"	"65.5"	"65.2"	"96.0"	"118.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O75396"	"Vesicle-trafficking protein SEC22b OS=Homo sapiens OX=9606 GN=SEC22B PE=1 SV=4"	""	""	"10"	"1"	"1"	"1"	"215"	"24.6"	"6.92"	""	"5.02"	""	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"24.8"	"15.9"	"24.4"	"21.9"	"23.2"	"23.6"	"33.0"	"77.2"	"96.7"	"248.3"	"333.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16537"	"Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform OS=Homo sapiens OX=9606 GN=PPP2R5E PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"467"	"54.7"	"6.95"	"532.23"	"5.01"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction"	"cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf01603"	"5529"	"ENSG00000154001"	"PPP2R5E"	"A4FU37; B7ZAW5; B7ZKK8; B7ZKK9; hsa:5529; J3KQN6; Q16537; Q52LW4"	"Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Wnt signaling pathway and pluripotency; PI3K-Akt signaling pathway; Glycogen synthesis and degradation; Cohesin complex - Cornelia de Lange syndrome; DNA damage response (only ATM dependent)"	"Resolution of Sister Chromatid Cohesion; CTLA4 inhibitory signaling; Separation of Sister Chromatids; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Negative regulation of MAPK pathway; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Disassembly of the destruction complex and recruitment of AXIN to the membrane; RAF activation; Beta-catenin phosphorylation cascade; Signaling by GSK3beta mutants; CTNNB1 S33 mutants aren't phosphorylated; CTNNB1 S37 mutants aren't phosphorylated; CTNNB1 S45 mutants aren't phosphorylated; CTNNB1 T41 mutants aren't phosphorylated; APC truncation mutants have impaired AXIN binding; AXIN missense mutants destabilize the destruction complex; Truncations of AMER1 destabilize the destruction complex; Platelet sensitization by LDL"	"28"	"0"	"29.6"	"18.2"	"41.8"	"29.5"	"21.1"	"26.3"	"35.2"	"59.5"	"71.5"	"139.9"	"172.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IZH2"	"5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1"	"0.000"	""	"1"	"2"	"3"	"2"	"1706"	"194.0"	"7.21"	"255.16"	"5.01"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03159, Pf17846, Pf18129, Pf18332, Pf18334"	"54464"	"ENSG00000114127"	"XRN1"	"hsa:54464; Q4G0S3; Q68D88; Q6AI24; Q6MZS8; Q86WS7; Q8IZH2; Q8N8U4; Q9UF39"	"miRNA degrading enzymes"	"mRNA decay by 5' to 3' exoribonuclease; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"	"4"	"0"	"25.4"	"11.2"	"28.1"	"29.3"	"27.3"	"21.5"	"39.3"	"53.6"	"57.9"	"130.3"	"153.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30038"	"Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH4A1 PE=1 SV=3"	"0.000"	""	"4"	"2"	"4"	"2"	"563"	"61.7"	"8.07"	"666.59"	"5.00"	"2"	"2"	"other metabolic processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf00171"	"8659"	"ENSG00000159423"	"ALDH4A1"	"A8K1Q7; B4DGE4; D2D4A3; hsa:8659; P30038; Q16882; Q53HU4; Q5JNV6; Q8IZ38; Q96IF0; Q9UDI6"	"22q11.2 copy number variation syndrome; p53 transcriptional gene network"	"Glyoxylate metabolism and glycine degradation; Proline catabolism"	"4"	"0"	"44.9"	"30.8"	"45.0"	"49.5"	"41.2"	"37.5"	"54.8"	"228.0"	"210.3"	"769.8"	"1034.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15843"	"NEDD8 OS=Homo sapiens OX=9606 GN=NEDD8 PE=1 SV=1"	"0.000"	""	"17"	"1"	"2"	"1"	"81"	"9.1"	"8.43"	"585.24"	"5.00"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00240"	"4738"	"ENSG00000129559; ENSG00000285246"	"NEDD8"	"hsa:4738; Q15843; Q3SXN8; Q6LES6"	"EGF/EGFR signaling pathway; 2q37 copy number variation syndrome"	"Cargo recognition for clathrin-mediated endocytosis; Neddylation; UCH proteinases; Iron uptake and transport; TGF-beta receptor signaling activates SMADs"	"7"	"0"	"116.9"	"89.9"	"147.1"	"124.5"	"96.1"	"95.4"	"129.7"	"203.6"	"178.4"	"470.9"	"920.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P28070"	"Proteasome subunit beta type-4 OS=Homo sapiens OX=9606 GN=PSMB4 PE=1 SV=4"	""	""	"9"	"1"	"1"	"1"	"264"	"29.2"	"5.97"	""	"4.99"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00227"	"5692"	"ENSG00000159377"	"PSMB4"	"B2R9L3; hsa:5692; P28070; P31148; Q5SZS5; Q6IBI4; Q969L6"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Regulation of expression of SLITs and ROBOs; Regulation of PTEN stability and activity; KEAP1-NFE2L2 pathway; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Neddylation; Interleukin-1 signaling; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"62"	"0"	"7.6"	"9.8"	"7.2"	"6.9"	"6.3"	"7.6"	"9.2"	"8.5"	"8.9"	"20.5"	"62.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86YB8"	"ERO1-like protein beta OS=Homo sapiens OX=9606 GN=ERO1B PE=1 SV=2"	"0.000"	""	"2"	"1"	"4"	"1"	"467"	"53.5"	"7.99"	"531.77"	"4.99"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf04137"	"56605"	"ENSG00000086619"	"ERO1B"	"B4DF57; hsa:56605; Q5T1H4; Q86YB8; Q8IZ11; Q9NR62"	""	"Insulin processing"	"1"	"0"	"19.8"	"10.6"	"22.8"	"15.2"	"21.4"	"21.7"	"19.2"	"72.8"	"98.6"	"153.2"	"209.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16763"	"Ubiquitin-conjugating enzyme E2 S OS=Homo sapiens OX=9606 GN=UBE2S PE=1 SV=2"	"0.000"	""	"7"	"1"	"2"	"1"	"222"	"23.8"	"8.38"	"507.24"	"4.98"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00179"	"27338"	"ENSG00000108106"	"UBE2S"	"hsa:27338; Q16763; Q9BTC1"	""	"Senescence-Associated Secretory Phenotype (SASP); Antigen processing: Ubiquitination & Proteasome degradation; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Separation of Sister Chromatids; CDK-mediated phosphorylation and removal of Cdc6; Autodegradation of Cdh1 by Cdh1:APC/C; Assembly of the pre-replicative complex; Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of Cyclin B; Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase; Regulation of APC/C activators between G1/S and early anaphase; Phosphorylation of the APC/C; APC-Cdc20 mediated degradation of Nek2A; Transcriptional Regulation by VENTX; Aberrant regulation of mitotic exit in cancer due to RB1 defects"	"19"	"0"	"9.9"	"8.6"	"11.9"	"8.5"	"10.5"	"14.1"	"14.7"	"36.5"	"36.2"	"80.8"	"110.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HAV0"	"Guanine nucleotide-binding protein subunit beta-4 OS=Homo sapiens OX=9606 GN=GNB4 PE=1 SV=3"	"0.000"	""	"5"	"1"	"2"	"1"	"340"	"37.5"	"6.00"	"428.14"	"4.96"	"1"	"1"	"signal transduction"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00400"	"59345"	"ENSG00000114450"	"GNB4"	"B3KMH5; D3DNR8; hsa:59345; Q9HAV0"	"Myometrial relaxation and contraction pathways; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Ras signaling; Calcium regulation in cardiac cells"	"G alpha (i) signalling events; G alpha (z) signalling events; ADP signalling through P2Y purinoceptor 12; Extra-nuclear estrogen signaling; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production; G alpha (12/13) signalling events; G alpha (q) signalling events; Thrombin signalling through proteinase activated receptors (PARs); Activation of G protein gated Potassium channels; G-protein activation; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; G beta:gamma signalling through PI3Kgamma; Prostacyclin signalling through prostacyclin receptor; Adrenaline,noradrenaline inhibits insulin secretion; Ca2+ pathway; G beta:gamma signalling through PLC beta; ADP signalling through P2Y purinoceptor 1; Glucagon-type ligand receptors; Thromboxane signalling through TP receptor; Vasopressin regulates renal water homeostasis via Aquaporins; Presynaptic function of Kainate receptors; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; G beta:gamma signalling through BTK; G beta:gamma signalling through CDC42; Inhibition  of voltage gated Ca2+ channels via Gbeta/gamma subunits; Glucagon signaling in metabolic regulation"	"34"	"0"	"15.7"	"13.1"	"19.9"	"19.1"	"16.7"	"15.6"	"17.5"	"49.0"	"58.4"	"182.9"	"306.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96E11"	"Ribosome-recycling factor, mitochondrial OS=Homo sapiens OX=9606 GN=MRRF PE=1 SV=1"	"0.000"	""	"13"	"2"	"3"	"2"	"262"	"29.3"	"9.79"	"251.44"	"4.96"	"1"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"mitochondrion"	"translation activity"	"Pf01765"	"92399"	"ENSG00000148187"	"MRRF"	"A8K6D8; A8K6Z4; B7Z4X5; B7Z6P7; hsa:92399; Q5RKT1; Q5T7T0; Q5T7T1; Q5T7T2; Q5T7T3; Q5T7T4; Q5T7T5; Q96E11"	""	"Mitochondrial translation termination"	"1"	"0"	"144.4"	"86.1"	"117.6"	"126.7"	"133.8"	"183.1"	"178.4"	"217.0"	"215.3"	"255.0"	"297.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6ZN04"	"RNA-binding protein MEX3B OS=Homo sapiens OX=9606 GN=MEX3B PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"569"	"58.8"	"6.90"	"446.84"	"4.96"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf13920"	"84206"	"ENSG00000183496"	"MEX3B"	"hsa:84206; Q4G0W1; Q6ZN04; Q8IVG2; Q9H0J0"	""	""	"0"	"0"	"10.7"	"15.9"	"12.6"	"9.7"	"11.0"	"16.6"	"15.4"	"22.5"	"21.5"	"35.8"	"46.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P63272"	"Transcription elongation factor SPT4 OS=Homo sapiens OX=9606 GN=SUPT4H1 PE=1 SV=1"	""	""	"17"	"1"	"1"	"1"	"117"	"13.2"	"8.06"	""	"4.96"	""	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf06093"	"6827"	"ENSG00000213246"	"SUPT4H1"	"B2R4X8; D3DTZ4; hsa:6827; P63272; Q16550; Q62387; Q6ZP89"	"Initiation of transcription and translation elongation at the HIV-1 LTR"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes"	"16"	"0"	"50.4"	"48.6"	"31.5"	"36.6"	"36.5"	"18.8"	"56.5"	"103.8"	"83.1"	"135.3"	"192.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NF91"	"Nesprin-1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=4"	"0.000"	""	"0"	"2"	"3"	"1"	"8797"	"1010.5"	"5.53"	"257.45"	"4.96"	"1"	"2"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00435, Pf10541"	"23345"	"ENSG00000131018"	"SYNE1"	"B3W695; E7EQI5; H0Y4C0; hsa:23345; O94890; Q3ZCV0; Q5JV19; Q5JV22; Q8N9P7; Q8NF91; Q8TCP1; Q8WWW6; Q8WWW7; Q8WXF6; Q96N17; Q9C0A7; Q9H525; Q9H526; Q9NS36; Q9NU50; Q9UJ06; Q9UJ07; Q9ULF8"	"Envelope proteins and their potential roles in EDMD physiopathology"	"Meiotic synapsis"	"2"	"0"	"13.3"	"7.9"	"15.5"	"15.7"	"14.6"	"11.4"	"16.3"	"59.5"	"58.7"	"310.0"	"526.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16204"	"Coiled-coil domain-containing protein 6 OS=Homo sapiens OX=9606 GN=CCDC6 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"474"	"53.3"	"7.34"	"440.54"	"4.95"	"1"	"1"	"cell organization and biogenesis"	"cytosol;cytoskeleton"	"cytoskeletal activity;other molecular function"	"Pf09755"	"8030"	"ENSG00000108091"	"CCDC6"	"hsa:8030; Q15250; Q16204; Q6GSG7"	"Retinoblastoma gene in cancer; Mesodermal commitment pathway; 16p11.2 proximal deletion syndrome"	""	"3"	"0"	"84.0"	"55.0"	"75.3"	"75.9"	"77.3"	"76.5"	"102.2"	"210.1"	"191.7"	"360.0"	"446.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9ULU4"	"Protein kinase C-binding protein 1 OS=Homo sapiens OX=9606 GN=ZMYND8 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"1186"	"131.6"	"7.20"	""	"4.94"	""	"1"	"cell organization and biogenesis;DNA metabolism;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00439, Pf00855, Pf12064"	"23613"	"ENSG00000101040"	"ZMYND8"	"B3KVL2; B7Z2A8; B7Z3E0; B7Z680; B7ZM62; E1P5U5; F5H0X3; H7C0U2; hsa:23613; J3KPU3; Q13517; Q2HXV1; Q2HXV2; Q2HXV3; Q2HXV4; Q2HXV7; Q2HXV8; Q2HXV9; Q2HXW0; Q2HXW1; Q2HXW2; Q4JJ94; Q4JJ95; Q5TH09; Q5TH11; Q6MZM1; Q8WXC5; Q9H1F3; Q9H1F4; Q9H1F5; Q9H1L8; Q9H1L9; Q9H2G5; Q9NYN3; Q9UIX6; Q9ULU4"	""	""	"0"	"0"	"13.9"	"6.7"	"12.2"	"12.8"	"10.7"	"14.5"	"12.9"	"20.5"	"17.7"	"42.5"	"81.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P10155"	"60 kDa SS-A/Ro ribonucleoprotein OS=Homo sapiens OX=9606 GN=RO60 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"538"	"60.6"	"8.03"	"556.05"	"4.93"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05731"	"6738"	"ENSG00000116747"	"RO60"	"B2RBB9; hsa:6738; P10155; Q5LJ98; Q5LJ99; Q5LJA0; Q86WL3; Q86WL4; Q92787; Q9H1W6"	""	""	"0"	"0"	"119.0"	"98.2"	"129.2"	"112.1"	"114.4"	"121.2"	"168.4"	"231.3"	"212.7"	"364.8"	"487.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52926"	"High mobility group protein HMGI-C OS=Homo sapiens OX=9606 GN=HMGA2 PE=1 SV=1"	"0.000"	""	"50"	"3"	"4"	"3"	"109"	"11.8"	"10.62"	"1034.25"	"4.93"	"2"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02178"	"8091"	"ENSG00000149948"	"HMGA2"	"E7EP85; E7EWA2; hsa:8091; P52926; Q1M182; Q1M185; Q1M186; Q1M187; Q1M188"	"Mesodermal commitment pathway; Mesodermal commitment pathway; Influence of laminopathies on Wnt signaling; Overlap between signal transduction pathways contributing to LMNA laminopathies; Orexin receptor pathway"	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"	"6"	"0"	"70.4"	"75.1"	"82.5"	"75.9"	"74.4"	"83.6"	"97.7"	"148.7"	"166.0"	"387.0"	"430.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O75691"	"Small subunit processome component 20 homolog OS=Homo sapiens OX=9606 GN=UTP20 PE=1 SV=3"	""	""	"1"	"1"	"2"	"1"	"2785"	"318.2"	"7.39"	""	"4.93"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	""	"Pf07539, Pf20416"	"27340"	"ENSG00000120800"	"UTP20"	"hsa:27340; O75691; Q9H3H4"	""	"rRNA modification in the nucleus and cytosol; Major pathway of rRNA processing in the nucleolus and cytosol"	"2"	"0"	"287.3"	"74.7"	"502.9"	"342.2"	"385.5"	"382.3"	"457.9"	"517.5"	"567.9"	"935.1"	"1040.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UFC0"	"Leucine-rich repeat and WD repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=LRWD1 PE=1 SV=2"	"0.000"	""	"2"	"2"	"4"	"2"	"647"	"70.8"	"7.21"	"568.04"	"4.92"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	""	"222229"	"ENSG00000161036"	"LRWD1"	"A8K4K2; B2R9G2; hsa:222229; Q8N0T9; Q8WV43; Q96GJ2; Q9UFC0"	"Male infertility"	""	"1"	"0"	"66.6"	"47.3"	"61.7"	"57.8"	"50.1"	"58.3"	"77.7"	"171.6"	"221.3"	"573.5"	"814.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BXY0"	"Protein MAK16 homolog OS=Homo sapiens OX=9606 GN=MAK16 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"300"	"35.3"	"5.38"	"452.24"	"4.91"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf01778, Pf04874"	"84549"	"ENSG00000198042"	"MAK16"	"B2RB44; hsa:84549; Q5U5T1; Q86UC4; Q96SY6; Q9BXY0"	""	""	"0"	"0"	"101.2"	"94.6"	"112.4"	"107.0"	"93.9"	"92.8"	"118.3"	"148.5"	"139.7"	"221.4"	"352.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P12931"	"Proto-oncogene tyrosine-protein kinase Src OS=Homo sapiens OX=9606 GN=SRC PE=1 SV=3"	"0.000"	""	"5"	"2"	"3"	"1"	"536"	"59.8"	"7.42"	"949.32"	"4.91"	"2"	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;kinase activity;other molecular function"	"Pf00017, Pf00018, Pf07714"	"6714"	"ENSG00000197122"	"SRC"	"E1P5V4; hsa:6714; P12931; Q76P87; Q86VB9; Q9H5A8"	"Androgen receptor signaling pathway; Angiogenesis; Integrin-mediated cell adhesion; RANKL/RANK signaling pathway; Thyroid stimulating hormone (TSH) signaling pathway; Leptin signaling pathway; Follicle stimulating hormone (FSH) signaling pathway; Prolactin signaling pathway; Microtubule cytoskeleton regulation; Thymic stromal lymphopoietin (TSLP) signaling pathway; Glioblastoma signaling pathways; AGE/RAGE pathway; Interleukin-11 signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Alpha 6 beta 4 signaling pathway; Aryl hydrocarbon receptor pathway; Bladder cancer; IL-3 signaling pathway; Aryl hydrocarbon receptor pathway; Pregnane X receptor pathway; Nuclear receptors meta-pathway; Kit receptor signaling pathway; Focal adhesion; Hepatocyte growth factor receptor signaling; RAC1/PAK1/p38/MMP2 pathway; Amplification and expansion of oncogenic pathways as metastatic traits; Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; Robo4 and VEGF signaling pathways crosstalk; Fibrin complement receptor 3 signaling pathway; Acute viral myocarditis; NRF2-ARE regulation; EGF/EGFR signaling pathway; Relationship between inflammation, COX-2 and EGFR; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Fragile X syndrome; Gastrin signaling pathway; Hepatitis B infection; Thyroid hormones production and peripheral downstream signaling effects; Netrin-UNC5B signaling pathway; EGFR tyrosine kinase inhibitor resistance; Pleural mesothelioma; CCL18 signaling pathway; GDNF signaling; TROP2 regulatory signaling; A network map of Macrophage-stimulating protein (MSP) signaling; 5q35 copy number variation; EPO receptor signaling; Notch signaling pathway; ErbB signaling pathway"	"G alpha (i) signalling events; Extra-nuclear estrogen signaling; GPER1 signaling; PIP3 activates AKT signaling; Signaling by BRAF and RAF1 fusions; Regulation of RUNX3 expression and activity; RHOU GTPase cycle; Constitutive Signaling by Aberrant PI3K in Cancer; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; DCC mediated attractive signaling; Downstream signal transduction; Signaling by ERBB2; Nuclear signaling by ERBB4; RAF activation; GAB1 signalosome; MET activates PTK2 signaling; Signaling by CSF1 (M-CSF) in myeloid cells; RUNX2 regulates osteoblast differentiation; Long-term potentiation; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; InlA-mediated entry of Listeria monocytogenes into host cells; Regulation of commissural axon pathfinding by SLIT and ROBO; Netrin mediated repulsion signals; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; GRB2:SOS provides linkage to MAPK signaling for Integrins ; p130Cas linkage to MAPK signaling for integrins; Activated NTRK2 signals through FYN; Downregulation of ERBB4 signaling; Regulation of RUNX1 Expression and Activity; Activated NTRK3 signals through PI3K"	"87"	"0"	"15.7"	"4.7"	"7.9"	"7.0"	"6.6"	"7.0"	"10.9"	"51.4"	"55.0"	"210.0"	"453.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96LT9"	"RNA-binding region-containing protein 3 OS=Homo sapiens OX=9606 GN=RNPC3 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"517"	"58.5"	"7.72"	"503.88"	"4.89"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076"	"55599"	"ENSG00000185946"	"RNPC3"	"A8K1C9; D3DT74; hsa:55599; Q5TZ87; Q96FK7; Q96JI8; Q96LT9; Q9NSU7; Q9NXX2"	""	"mRNA Splicing - Minor Pathway"	"1"	"0"	"29.7"	"22.0"	"33.9"	"40.6"	"42.2"	"21.6"	"33.0"	"54.1"	"56.3"	"112.1"	"139.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94813"	"Slit homolog 2 protein OS=Homo sapiens OX=9606 GN=SLIT2 PE=1 SV=1"	"0.000"	""	"2"	"2"	"3"	"2"	"1529"	"169.8"	"7.06"	"1041.17"	"4.88"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;other membranes;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00008, Pf01462, Pf01463, Pf02210, Pf12661, Pf13855"	"9353"	"ENSG00000145147"	"SLIT2"	"A0A0A6YYB8; B7ZLR5; hsa:9353; O94813; O95710; Q17RU3; Q9Y5Q7"	"Spinal cord injury; Robo4 and VEGF signaling pathways crosstalk; Genes controlling nephrogenesis; GDNF/RET signaling axis; Development of ureteric collection system"	"Regulation of expression of SLITs and ROBOs; Netrin-1 signaling; Inactivation of CDC42 and RAC1; Activation of RAC1; Regulation of commissural axon pathfinding by SLIT and ROBO; Role of ABL in ROBO-SLIT signaling; SLIT2:ROBO1 increases RHOA activity"	"13"	"0"	"117.7"	"93.8"	"130.9"	"95.6"	"115.1"	"74.5"	"149.3"	"238.8"	"218.7"	"470.0"	"665.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UFF9"	"CCR4-NOT transcription complex subunit 8 OS=Homo sapiens OX=9606 GN=CNOT8 PE=1 SV=1"	""	""	"8"	"2"	"2"	"2"	"292"	"33.5"	"4.81"	""	"4.88"	""	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04857"	"9337"	"ENSG00000155508"	"CNOT8"	"B0AZS3; B2RAR8; B7Z8R1; D3DQI8; hsa:9337; O95709; Q7Z521; Q9H6Y1; Q9UFF9"	""	"Deadenylation of mRNA; TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"	"2"	"0"	"35.2"	"29.1"	"54.6"	"39.2"	"43.8"	"38.2"	"47.1"	"70.9"	"55.9"	"138.8"	"150.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q6P161"	"39S ribosomal protein L54, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL54 PE=1 SV=1"	""	""	"19"	"1"	"1"	"1"	"138"	"15.8"	"9.60"	""	"4.87"	""	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf08561"	"116541"	"ENSG00000183617"	"MRPL54"	"hsa:116541; Q6P161"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"27.3"	"21.8"	"30.0"	"29.0"	"25.6"	"21.9"	"36.3"	"46.9"	"51.2"	"79.9"	"91.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q00796"	"Sorbitol dehydrogenase OS=Homo sapiens OX=9606 GN=SORD PE=1 SV=4"	"0.000"	""	"5"	"2"	"4"	"2"	"357"	"38.3"	"7.97"	"596.48"	"4.86"	"2"	"2"	"other metabolic processes;stress response;other biological processes"	"non-structural extracellular;other membranes;cytosol;cytoskeleton;mitochondrion"	"other molecular function"	"Pf00107, Pf08240"	"6652"	"ENSG00000140263"	"SORD"	"B2R655; B7Z3A6; hsa:6652; J3JZZ5; Q00796; Q16682; Q9UMD6"	"Disorders of fructose metabolism; Polyol pathway"	"Formation of xylulose-5-phosphate; Fructose biosynthesis"	"4"	"0"	"135.5"	"131.7"	"170.6"	"152.2"	"176.6"	"161.3"	"209.8"	"239.5"	"217.8"	"423.9"	"635.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UHB7"	"AF4/FMR2 family member 4 OS=Homo sapiens OX=9606 GN=AFF4 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"1163"	"127.4"	"9.31"	"525.37"	"4.86"	"1"	"1"	"stress response;other biological processes"	"nucleus;other cell component"	""	"Pf05110, Pf18875, Pf18876"	"27125"	"ENSG00000072364"	"AFF4"	"B2RP19; B7WPD2; hsa:27125; Q498B2; Q59FB3; Q6P592; Q8TDR1; Q9P0E4; Q9UHB7"	""	"Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13155"	"Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 OS=Homo sapiens OX=9606 GN=AIMP2 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"320"	"35.3"	"8.22"	"365.52"	"4.86"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf14497, Pf16780, Pf18569"	"7965"	"ENSG00000106305"	"AIMP2"	"F8W950; hsa:7965; Q13155; Q75MR1; Q96CZ5; Q9P1L2"	"Osteoclast signaling; Transcriptional activation by NRF2 in response to phytochemicals; NRF2-ARE regulation"	"Cytosolic tRNA aminoacylation; Selenoamino acid metabolism"	"5"	"0"	"16.2"	"10.2"	"18.4"	"19.3"	"18.0"	"13.1"	"26.4"	"66.6"	"71.8"	"251.0"	"355.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96PY5"	"Formin-like protein 2 OS=Homo sapiens OX=9606 GN=FMNL2 PE=1 SV=3"	"0.000"	""	"2"	"2"	"4"	"2"	"1086"	"123.2"	"7.40"	"697.80"	"4.86"	"2"	"2"	"cell organization and biogenesis;other biological processes"	"cytosol"	"cytoskeletal activity;other molecular function"	"Pf02181, Pf06367, Pf06371"	"114793"	"ENSG00000157827"	"FMNL2"	"B2RZH5; hsa:114793; Q14CC9; Q4ZG52; Q8N3E0; Q96PY5"	"Epithelial to mesenchymal transition in colorectal cancer"	"RHO GTPases Activate Formins; CDC42 GTPase cycle; RHOC GTPase cycle"	"4"	"0"	"46.0"	"38.6"	"38.9"	"38.1"	"41.9"	"37.3"	"55.8"	"70.4"	"65.9"	"98.1"	"163.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60673"	"DNA polymerase zeta catalytic subunit OS=Homo sapiens OX=9606 GN=REV3L PE=1 SV=2"	"0.000"	""	"1"	"2"	"4"	"1"	"3130"	"352.6"	"8.47"	"548.66"	"4.85"	"2"	"2"	"DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00136, Pf03104, Pf14260, Pf15735"	"5980"	"ENSG00000009413"	"REV3L"	"hsa:5980; O43214; O60673; Q5TC33"	"DNA repair pathways, full network"	"Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UBQ7"	"Glyoxylate reductase/hydroxypyruvate reductase OS=Homo sapiens OX=9606 GN=GRHPR PE=1 SV=1"	""	""	"7"	"1"	"1"	"1"	"328"	"35.6"	"7.39"	""	"4.85"	""	"1"	"other metabolic processes"	"cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00389, Pf02826"	"9380"	"ENSG00000137106"	"GRHPR"	"hsa:9380; Q5T945; Q9H3E9; Q9H636; Q9UBQ7; Q9UKX1"	""	"Glyoxylate metabolism and glycine degradation"	"1"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"4.0"	"5.3"	"28.2"	"109.3"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96ES7"	"SAGA-associated factor 29 OS=Homo sapiens OX=9606 GN=SGF29 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"293"	"33.2"	"8.10"	"571.48"	"4.85"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf07039"	"112869"	"ENSG00000176476"	"SGF29"	"hsa:112869; Q96ES7; Q96MF5"	""	"HATs acetylate histones; Formation of WDR5-containing histone-modifying complexes"	"2"	"0"	"20.1"	"18.6"	"26.7"	"20.2"	"20.1"	"22.5"	"35.4"	"70.2"	"67.0"	"102.1"	"99.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BW85"	"Splicing factor YJU2 OS=Homo sapiens OX=9606 GN=YJU2 PE=1 SV=1"	"0.000"	""	"10"	"2"	"3"	"2"	"323"	"37.1"	"5.92"	"1097.15"	"4.84"	"2"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf04502"	"55702"	"ENSG00000105248"	"YJU2"	"hsa:55702; O75270; Q9BW85; Q9H862; Q9NW16"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"53.4"	"45.1"	"62.1"	"52.7"	"61.0"	"59.9"	"64.5"	"96.1"	"103.1"	"274.3"	"418.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H1A4"	"Anaphase-promoting complex subunit 1 OS=Homo sapiens OX=9606 GN=ANAPC1 PE=1 SV=1"	"0.000"	""	"2"	"3"	"5"	"3"	"1944"	"216.4"	"6.30"	"874.02"	"4.84"	"3"	"2"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf12859, Pf18122, Pf19521, Pf20518"	"64682"	"ENSG00000153107"	"ANAPC1"	"hsa:64682; Q2M3H8; Q9BSE6; Q9H1A4; Q9H8D0"	"Cell cycle; 2q13 copy number variation syndrome"	"Senescence-Associated Secretory Phenotype (SASP); Separation of Sister Chromatids; Antigen processing: Ubiquitination & Proteasome degradation; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; CDK-mediated phosphorylation and removal of Cdc6; Autodegradation of Cdh1 by Cdh1:APC/C; Assembly of the pre-replicative complex; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of Cyclin B; Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase; Regulation of APC/C activators between G1/S and early anaphase; Phosphorylation of the APC/C; APC-Cdc20 mediated degradation of Nek2A; Transcriptional Regulation by VENTX; Aberrant regulation of mitotic exit in cancer due to RB1 defects"	"20"	"0"	"80.2"	"55.1"	"91.4"	"74.1"	"65.6"	"77.8"	"101.3"	"178.0"	"165.0"	"375.4"	"503.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O60232"	"Protein ZNRD2 OS=Homo sapiens OX=9606 GN=ZNRD2 PE=1 SV=1"	""	""	"9"	"1"	"1"	"1"	"199"	"21.5"	"5.24"	""	"4.81"	""	"1"	"cell cycle OR cell proliferation;other biological processes"	""	""	"Pf06677"	"10534"	"ENSG00000173465"	"ZNRD2"	"hsa:10534; O60232"	""	""	"0"	"0"	"60.9"	"54.2"	"76.2"	"68.7"	"70.7"	"48.1"	"74.1"	"127.4"	"118.1"	"185.1"	"240.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15154"	"Pericentriolar material 1 protein OS=Homo sapiens OX=9606 GN=PCM1 PE=1 SV=5"	"0.000"	""	"1"	"2"	"4"	"1"	"2024"	"228.4"	"5.02"	"697.68"	"4.80"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf15717"	"5108"	"ENSG00000078674"	"PCM1"	"A6NNN6; B4DYD5; E7ETA6; E7EV56; hsa:5108; Q15154; Q58F13; Q6P1K7; Q8NB85; Q9BWC1; Q9H4A2"	"Prader-Willi and Angelman syndrome; Joubert syndrome"	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"9"	"0"	"108.1"	"106.0"	"80.2"	"88.1"	"80.2"	"66.4"	"115.1"	"157.9"	"132.6"	"200.9"	"318.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61758"	"Prefoldin subunit 3 OS=Homo sapiens OX=9606 GN=VBP1 PE=1 SV=4"	"0.000"	""	"16"	"2"	"3"	"2"	"197"	"22.6"	"7.11"	"281.68"	"4.80"	"1"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02996"	"7411"	"ENSG00000155959"	"VBP1"	"B2R8L5; B4DWR3; F5H2A7; hsa:7411; O55228; P61758; Q15765; Q5JT81; Q86X96"	"Cellular proteostasis"	"Prefoldin mediated transfer of substrate  to CCT/TriC"	"2"	"0"	"73.1"	"59.9"	"73.1"	"72.7"	"57.9"	"60.7"	"83.1"	"154.0"	"142.9"	"401.4"	"692.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y371"	"Endophilin-B1 OS=Homo sapiens OX=9606 GN=SH3GLB1 PE=1 SV=1"	""	""	"6"	"1"	"1"	"1"	"365"	"40.8"	"6.04"	""	"4.79"	""	"1"	"cell organization and biogenesis;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf03114, Pf14604"	"51100"	"ENSG00000097033"	"SH3GLB1"	"B4E182; hsa:51100; Q5H8U5; Q9H3Z0; Q9NR47; Q9NYA9; Q9Y371"	"Nanoparticle triggered autophagic cell death"	""	"1"	"0"	"9.9"	"6.3"	"7.1"	"7.7"	"11.1"	"8.2"	"5.8"	"16.2"	"15.5"	"54.6"	"66.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NYJ1"	"Cytochrome c oxidase assembly factor 4 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=COA4 PE=1 SV=2"	"0.000"	""	"20"	"2"	"3"	"2"	"87"	"10.1"	"6.04"	"1071.27"	"4.79"	"2"	"1"	"cell organization and biogenesis"	"mitochondrion"	""	""	"51287"	"ENSG00000181924"	"COA4"	"B2RAA0; hsa:51287; Q69YU4; Q9NYJ1"	""	"Mitochondrial protein import"	"1"	"0"	"136.8"	"113.1"	"166.9"	"156.6"	"149.3"	"138.2"	"165.5"	"193.2"	"181.8"	"214.6"	"248.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61221"	"ATP-binding cassette sub-family E member 1 OS=Homo sapiens OX=9606 GN=ABCE1 PE=1 SV=1"	"0.000"	""	"5"	"2"	"2"	"2"	"599"	"67.3"	"8.34"	"267.68"	"4.79"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;mitochondrion;translational apparatus;other cell component"	"enzyme regulator activity;translation activity;other molecular function"	"Pf00005, Pf00037, Pf04068"	"6059"	"ENSG00000164163"	"ABCE1"	"hsa:6059; O88793; P61221; Q13181; Q13864; Q6NR76; Q96AL0; Q96B10; Q99K66"	""	"OAS antiviral response; Interferon alpha/beta signaling"	"2"	"0"	"94.8"	"76.9"	"110.4"	"99.0"	"97.4"	"106.4"	"129.7"	"275.2"	"289.8"	"565.9"	"732.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BXB4"	"Oxysterol-binding protein-related protein 11 OS=Homo sapiens OX=9606 GN=OSBPL11 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"747"	"83.6"	"7.06"	"479.12"	"4.79"	"1"	"1"	"transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf00169, Pf01237"	"114885"	"ENSG00000144909"	"OSBPL11"	"A8K9I7; hsa:114885; Q9BXB4"	""	"RHOH GTPase cycle"	"1"	"0"	"21.8"	"13.9"	"16.3"	"17.2"	"13.8"	"17.7"	"22.2"	"26.9"	"34.5"	"59.6"	"75.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UHR6"	"Zinc finger HIT domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ZNHIT2 PE=1 SV=1"	""	""	"7"	"1"	"1"	"1"	"403"	"42.9"	"5.99"	""	"4.78"	""	"1"	""	""	"other molecular function"	"Pf04438"	"741"	"ENSG00000174276"	"ZNHIT2"	"hsa:741; Q3SY14; Q8IUV0; Q9UHR6"	""	""	"0"	"0"	"11.8"	"8.4"	"9.8"	"14.4"	"9.9"	"12.9"	"14.8"	"22.8"	"19.2"	"42.9"	"67.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96HR8"	"H/ACA ribonucleoprotein complex non-core subunit NAF1 OS=Homo sapiens OX=9606 GN=NAF1 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"494"	"53.7"	"4.87"	"388.38"	"4.78"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04410"	"92345"	"ENSG00000145414"	"NAF1"	"D3DP28; E9PAZ2; hsa:92345; Q96HR8"	""	""	"0"	"0"	"17.7"	"14.5"	"29.3"	"22.7"	"18.0"	"21.3"	"34.6"	"59.6"	"51.4"	"130.6"	"180.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15643"	"Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3"	"0.000"	""	"1"	"3"	"5"	"1"	"1979"	"227.4"	"5.26"	"786.33"	"4.78"	"3"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;cytoskeleton;ER/Golgi"	"other molecular function"	""	"9321"	"ENSG00000100815"	"TRIP11"	"B2RUT2; hsa:9321; O14689; O15154; O95949; Q15643; Q6MZL5"	""	"Intraflagellar transport; Intra-Golgi traffic; Signaling by FLT3 fusion proteins"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P34896"	"Serine hydroxymethyltransferase, cytosolic OS=Homo sapiens OX=9606 GN=SHMT1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"483"	"53.0"	"7.71"	"412.31"	"4.77"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00464"	"6470"	"ENSG00000176974; ENSG00000284320"	"SHMT1"	"B4DPM9; D3DXD0; hsa:6470; P34896; Q96HY0; Q9UMD1; Q9UMD2"	"Glycine metabolism; Folate metabolism; One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways; Clear cell renal cell carcinoma pathways; Male infertility; Neuroinflammation and glutamatergic signaling; Metabolic Epileptic Disorders; Smith-Magenis and Potocki-Lupski syndrome copy number variation"	"Metabolism of folate and pterines; Carnitine synthesis"	"11"	"0"	"57.4"	"50.4"	"69.8"	"63.2"	"50.9"	"56.7"	"76.7"	"120.2"	"98.3"	"236.3"	"341.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12923"	"Tyrosine-protein phosphatase non-receptor type 13 OS=Homo sapiens OX=9606 GN=PTPN13 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"2485"	"276.7"	"6.42"	"469.17"	"4.77"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00102, Pf00373, Pf00595, Pf09379, Pf09380, Pf16599"	"5783"	"ENSG00000163629"	"PTPN13"	"B2RTR0; hsa:5783; Q12923; Q15159; Q15263; Q15264; Q15265; Q15674; Q16826; Q8IWH7; Q9NYN9; Q9UDA8"	"Apoptosis modulation and signaling; Ectoderm differentiation; Ectoderm differentiation"	"RND2 GTPase cycle; Synthesis of PIPs at the plasma membrane; RND3 GTPase cycle; RND1 GTPase cycle; Interleukin-37 signaling"	"8"	"0"	"21.4"	"14.1"	"26.7"	"22.9"	"20.0"	"20.8"	"29.5"	"49.7"	"49.7"	"129.4"	"195.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95671"	"Probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein OS=Homo sapiens OX=9606 GN=ASMTL PE=1 SV=3"	"0.000"	""	"4"	"2"	"3"	"2"	"621"	"68.8"	"6.07"	"779.52"	"4.76"	"2"	"1"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf00891, Pf02545, Pf16864"	"8623"	"ENSG00000169093"	"ASMTL"	"B4DX75; F5GXH4; hsa:8623; J3JS33; O95671; Q5JQ53; Q8NBH5; Q96G02; Q9BUL6"	""	""	"0"	"0"	"8.2"	"7.7"	"6.3"	"7.0"	"10.7"	"13.7"	"10.7"	"22.2"	"27.3"	"94.1"	"150.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WWQ0"	"PH-interacting protein OS=Homo sapiens OX=9606 GN=PHIP PE=1 SV=2"	"0.000"	""	"1"	"2"	"3"	"2"	"1821"	"206.6"	"8.85"	"274.69"	"4.75"	"1"	"2"	"cell organization and biogenesis;signal transduction;other biological processes"	"nucleus"	"signal transduction activity or receptor binding;other molecular function"	"Pf00400, Pf00439"	"55023"	"ENSG00000146247"	"PHIP"	"A7J992; B2RPK4; hsa:55023; Q05CQ9; Q5VVH4; Q66I29; Q69YV1; Q8NBZ5; Q8WWQ0; Q96H52; Q96ME2; Q9H261"	""	"RHOBTB2 GTPase cycle"	"1"	"0"	"188.7"	"161.3"	"173.9"	"180.2"	"162.3"	"175.2"	"216.2"	"249.1"	"239.7"	"471.7"	"744.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H000"	"Probable E3 ubiquitin-protein ligase makorin-2 OS=Homo sapiens OX=9606 GN=MKRN2 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"416"	"46.9"	"7.61"	"377.17"	"4.74"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00097, Pf00642, Pf14608, Pf18044"	"23609"	"ENSG00000075975"	"MKRN2"	"A6NIA2; B3KRC5; B4DPR4; hsa:23609; Q8N391; Q96BD4; Q9BUY2; Q9H000; Q9NRY1"	""	""	"0"	"0"	"35.2"	"24.8"	"55.2"	"44.5"	"39.7"	"40.5"	"57.7"	"101.4"	"98.8"	"282.6"	"408.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q53EL6"	"Programmed cell death protein 4 OS=Homo sapiens OX=9606 GN=PDCD4 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"469"	"51.7"	"5.21"	"347.77"	"4.73"	"1"	"1"	"developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf02847"	"27250"	"ENSG00000150593"	"PDCD4"	"B2RCV4; B5ME91; hsa:27250; O15501; Q53EL6; Q5VZS6; Q6PJI5; Q8TAR5; Q99834"	"Translation inhibitors in chronically activated PDGFRA cells; A network map of Macrophage-stimulating protein (MSP) signaling; Interferon type I signaling pathways"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	"4"	"0"	"6.7"	"7.7"	"6.5"	"14.6"	"11.2"	"8.3"	"15.9"	"33.0"	"33.4"	"142.1"	"344.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q93034"	"Cullin-5 OS=Homo sapiens OX=9606 GN=CUL5 PE=1 SV=4"	"0.000"	""	"2"	"1"	"2"	"1"	"780"	"90.9"	"7.94"	"355.40"	"4.73"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;transport;signal transduction"	"cytosol;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf00888, Pf10557"	"8065"	"ENSG00000166266"	"CUL5"	"A8K960; hsa:8065; O14766; Q93034; Q9BZC6"	"Apoptosis-related network due to altered Notch3 in ovarian cancer; Dual hijack model of Vif in HIV infection; Modulators of TCR signaling and T cell activation; 10q11.21q11.23 copy number variation syndrome"	"Antigen processing: Ubiquitination & Proteasome degradation; Vif-mediated degradation of APOBEC3G; Neddylation; Inactivation of CSF3 (G-CSF) signaling; Downregulation of ERBB2 signaling"	"9"	"0"	"7.1"	"3.4"	"4.3"	"5.3"	"9.1"	"10.8"	"10.2"	"40.6"	"45.0"	"160.0"	"256.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P31040"	"Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHA PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"664"	"72.6"	"7.39"	"547.47"	"4.72"	"2"	"2"	"other metabolic processes;developmental processes"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf00890, Pf02910"	"6389"	"ENSG00000073578"	"SDHA"	"A8K5J6; B4DJ60; E9PBJ5; hsa:6389; P31040; Q16395; Q59GW8; Q8IW48; Q9UMY5"	"Electron transport chain: OXPHOS system in mitochondria; TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Nonalcoholic fatty liver disease; Mitochondrial complex II assembly; Arsenic metabolism and reactive oxygen species generation; TCA cycle (aka Krebs or citric acid cycle)"	"Respiratory electron transport; Citric acid cycle (TCA cycle)"	"9"	"0"	"115.4"	"85.6"	"101.3"	"94.3"	"88.1"	"94.6"	"131.2"	"204.0"	"208.7"	"425.0"	"589.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9ULJ8"	"Neurabin-1 OS=Homo sapiens OX=9606 GN=PPP1R9A PE=1 SV=2"	"0.000"	""	"2"	"3"	"4"	"3"	"1098"	"123.3"	"5.10"	"590.89"	"4.72"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf00595, Pf07647, Pf17817"	"55607"	"ENSG00000158528"	"PPP1R9A"	"A1L494; B2RWQ1; E9PCA0; E9PCK6; E9PDX1; F8W7J9; hsa:55607; O76059; Q9NXT2; Q9ULJ8"	"Perturbations to host-cell autophagy, induced by SARS-CoV-2 proteins"	""	"1"	"0"	"234.1"	"190.7"	"215.9"	"216.6"	"202.0"	"243.3"	"296.8"	"480.3"	"478.0"	"1218.3"	"2018.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5PRF9"	"Protein Smaug homolog 2 OS=Homo sapiens OX=9606 GN=SAMD4B PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"694"	"75.4"	"6.83"	"503.95"	"4.71"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00536"	"55095"	"ENSG00000179134"	"SAMD4B"	"A5Z0M6; hsa:55095; Q5PRF9; Q6P194"	""	""	"0"	"0"	"7.6"	"4.3"	"7.4"	"7.7"	"5.2"	"6.7"	"6.8"	"17.8"	"21.0"	"62.3"	"80.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08195"	"4F2 cell-surface antigen heavy chain OS=Homo sapiens OX=9606 GN=SLC3A2 PE=1 SV=3"	"0.000"	""	"4"	"2"	"4"	"2"	"630"	"68.0"	"5.01"	"766.40"	"4.70"	"2"	"2"	"other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;nucleus;other cytoplasmic organelle;other cell component"	"transporter activity;nucleic acid binding activity"	"Pf00128, Pf16028"	"6520"	"ENSG00000168003"	"SLC3A2"	"hsa:6520; J3KPF3; P08195; Q13543"	"mRNA, protein, and metabolite inducation pathway by cyclosporin A; Ferroptosis; Proximal tubule transport; Pleural mesothelioma"	"Tryptophan catabolism; Basigin interactions; Amino acid transport across the plasma membrane; Defective SLC7A7 causes lysinuric protein intolerance (LPI)"	"8"	"0"	"6.9"	"0.0"	"12.1"	"6.9"	"4.4"	"6.7"	"7.4"	"15.0"	"20.3"	"56.5"	"69.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6UVY6"	"DBH-like monooxygenase protein 1 OS=Homo sapiens OX=9606 GN=MOXD1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"613"	"69.6"	"6.43"	"504.58"	"4.70"	"1"	"1"	"other metabolic processes"	"non-structural extracellular;other membranes;ER/Golgi"	"other molecular function"	"Pf01082, Pf03351, Pf03712"	"26002"	"ENSG00000079931"	"MOXD1"	"hsa:26002; Q5THU6; Q6UVY6; Q8NC97; Q8WV49; Q9H4M6; Q9Y4U3"	""	""	"0"	"0"	"21.9"	"16.0"	"14.0"	"19.8"	"17.0"	"21.4"	"22.6"	"72.5"	"64.2"	"302.0"	"579.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NYB9"	"Abl interactor 2 OS=Homo sapiens OX=9606 GN=ABI2 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"513"	"55.6"	"6.16"	"398.15"	"4.70"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf07815, Pf14604"	"10152"	"ENSG00000138443"	"ABI2"	"B4DSN1; hsa:10152; Q13147; Q13249; Q13801; Q9BV70; Q9NYB9"	"Regulation of actin cytoskeleton"	"VEGFA-VEGFR2 Pathway; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs"	"8"	"0"	"61.3"	"53.6"	"76.7"	"58.9"	"69.9"	"68.4"	"89.3"	"170.8"	"170.0"	"346.9"	"417.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z4G4"	"tRNA (guanine(10)-N2)-methyltransferase homolog OS=Homo sapiens OX=9606 GN=TRMT11 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"463"	"53.4"	"7.78"	"528.87"	"4.70"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01170"	"60487"	"ENSG00000066651"	"TRMT11"	"E1P570; hsa:60487; Q5JY11; Q6PGQ5; Q7Z4G4; Q9HC13"	""	"tRNA modification in the nucleus and cytosol"	"1"	"0"	"70.0"	"41.3"	"54.4"	"54.4"	"53.4"	"60.5"	"58.1"	"159.3"	"158.0"	"496.8"	"831.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8IV48"	"3'-5' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=ERI1 PE=1 SV=3"	""	""	"2"	"1"	"2"	"1"	"349"	"40.0"	"6.70"	""	"4.68"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00929, Pf02037"	"90459"	"ENSG00000104626"	"ERI1"	"A8K4U7; hsa:90459; Q8IV48; Q9NSX3"	"exRNA mechanism of action and biogenesis; 8p23.1 copy number variation syndrome; 4p16.3 copy number variation"	"Major pathway of rRNA processing in the nucleolus and cytosol"	"4"	"0"	"42.5"	"38.0"	"43.3"	"38.4"	"41.2"	"39.3"	"54.1"	"253.1"	"337.4"	"710.0"	"629.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09132"	"Signal recognition particle 19 kDa protein OS=Homo sapiens OX=9606 GN=SRP19 PE=1 SV=3"	"0.000"	""	"10"	"1"	"2"	"1"	"144"	"16.1"	"9.85"	"435.41"	"4.67"	"1"	"1"	"cell organization and biogenesis;transport"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01922"	"6728"	"ENSG00000153037"	"SRP19"	"B2R4E9; D6RCQ5; hsa:6728; P09132; Q05D77; Q96FG6"	""	"SRP-dependent cotranslational protein targeting to membrane"	"1"	"0"	"69.3"	"54.3"	"78.6"	"69.0"	"67.9"	"73.0"	"97.2"	"126.7"	"118.9"	"254.0"	"449.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q6WRX3"	"Protein zyg-11 homolog A OS=Homo sapiens OX=9606 GN=ZYG11A PE=2 SV=3"	""	""	"3"	"1"	"2"	"1"	"759"	"85.8"	"7.97"	""	"4.67"	""	"1"	""	"other cell component"	""	""	"440590"	"ENSG00000203995"	"ZYG11A"	"A6NCK5; hsa:440590; Q6WRX3"	""	""	"0"	"0"	"24.0"	"16.4"	"28.4"	"22.8"	"27.6"	"21.6"	"35.4"	"241.0"	"232.5"	"517.2"	"809.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8IU81"	"Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"584"	"61.6"	"8.18"	""	"4.67"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00097, Pf11261"	"26145"	"ENSG00000170604"	"IRF2BP1"	"hsa:26145; Q53EL7; Q6DC95; Q8IU81; Q9BRZ9; Q9Y4P4"	""	""	"0"	"0"	"31.2"	"25.2"	"27.3"	"23.9"	"32.7"	"39.1"	"56.6"	"175.0"	"201.6"	"431.6"	"592.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q69YQ0"	"Cytospin-A OS=Homo sapiens OX=9606 GN=SPECC1L PE=1 SV=2"	"0.000"	""	"2"	"3"	"5"	"1"	"1117"	"124.5"	"5.72"	"930.13"	"4.66"	"2"	"2"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"68.5"	"52.1"	"64.4"	"57.2"	"51.6"	"50.6"	"72.3"	"125.5"	"130.9"	"260.7"	"295.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EV2"	"RNA-binding protein 33 OS=Homo sapiens OX=9606 GN=RBM33 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"1170"	"129.9"	"6.93"	"553.28"	"4.66"	"1"	"1"	""	""	""	""	"155435"	"ENSG00000184863"	"RBM33"	"A4D244; B5MC24; hsa:155435; Q52LF5; Q75LN9; Q75ML5; Q96EV2; Q9NSV0"	""	""	"0"	"0"	"89.5"	"71.7"	"94.4"	"88.2"	"94.4"	"90.5"	"106.1"	"172.8"	"159.4"	"294.0"	"337.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H081"	"Protein MIS12 homolog OS=Homo sapiens OX=9606 GN=MIS12 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"205"	"24.1"	"5.69"	"403.48"	"4.66"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf05859"	"79003"	"ENSG00000167842"	"MIS12"	"hsa:79003; Q96N24; Q9H081"	""	"Resolution of Sister Chromatid Cohesion; Separation of Sister Chromatids; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"6"	"0"	"46.8"	"28.1"	"49.1"	"39.2"	"44.3"	"41.4"	"51.0"	"392.0"	"391.9"	"924.3"	"1121.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94966"	"Ubiquitin carboxyl-terminal hydrolase 19 OS=Homo sapiens OX=9606 GN=USP19 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"1318"	"145.6"	"6.28"	"662.67"	"4.65"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;ER/Golgi"	"other molecular function"	"Pf00443, Pf01753, Pf04969, Pf16602"	"10869"	"ENSG00000172046"	"USP19"	"A5PKX8; A6H8U2; B4DGT3; B4DTZ0; E7EN22; E7ETS0; E9PEG8; hsa:10869; O94966; Q3KQW4; Q641Q9; Q6NZY8; Q86XV9"	"Warburg effect modulated by deubiquitinating enzymes and their substrates"	"Ub-specific processing proteases"	"2"	"0"	"6.0"	"0.0"	"5.9"	"5.8"	"3.5"	"4.6"	"6.7"	"18.2"	"24.6"	"53.2"	"91.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VWN6"	"Protein TASOR 2 OS=Homo sapiens OX=9606 GN=TASOR2 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"2430"	"268.7"	"5.90"	"493.26"	"4.64"	"1"	"1"	"cell organization and biogenesis"	"cytosol;nucleus"	""	"Pf12480, Pf12509"	"54906"	"ENSG00000108021"	"TASOR2"	"hsa:54906; Q2YD91; Q5VWN5; Q5VWN6; Q6ZRQ8; Q8IVG4; Q9BUZ7; Q9H5J9; Q9H7A4; Q9H996; Q9NXA1"	""	""	"0"	"0"	"19.8"	"18.0"	"19.2"	"19.2"	"17.7"	"22.2"	"24.3"	"41.5"	"40.1"	"69.4"	"78.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BRT2"	"Ubiquinol-cytochrome-c reductase complex assembly factor 2 OS=Homo sapiens OX=9606 GN=UQCC2 PE=1 SV=1"	"0.000"	""	"10"	"1"	"2"	"1"	"126"	"14.9"	"7.37"	"369.11"	"4.64"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"other membranes;mitochondrion;nucleus"	""	"Pf20180"	"84300"	"ENSG00000137288"	"UQCC2"	"B2R4I0; hsa:84300; Q9BRT2"	"Mitochondrial complex III assembly"	""	"1"	"0"	"64.3"	"45.3"	"62.4"	"54.5"	"61.5"	"66.3"	"97.8"	"175.0"	"171.6"	"275.7"	"276.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IVL6"	"Prolyl 3-hydroxylase 3 OS=Homo sapiens OX=9606 GN=P3H3 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"736"	"81.8"	"6.32"	"464.50"	"4.63"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"ER/Golgi;other cell component"	"other molecular function"	"Pf13640"	"10536"	"ENSG00000110811"	"P3H3"	"hsa:10536; Q13512; Q15740; Q66K32; Q6NX61; Q7L2T1; Q8IVL6"	""	"Collagen biosynthesis and modifying enzymes"	"1"	"0"	"16.2"	"15.7"	"18.4"	"17.6"	"17.8"	"7.1"	"17.4"	"26.9"	"27.2"	"41.2"	"43.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99871"	"HAUS augmin-like complex subunit 7 OS=Homo sapiens OX=9606 GN=HAUS7 PE=1 SV=3"	"0.000"	""	"5"	"1"	"2"	"1"	"368"	"40.8"	"4.83"	"491.37"	"4.63"	"1"	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"3.1"	"7.4"	"9.5"	"9.7"	"6.7"	"7.6"	"8.7"	"22.3"	"23.4"	"51.4"	"70.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30050"	"60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1"	"0.000"	""	"15"	"3"	"5"	"3"	"165"	"17.8"	"9.42"	"936.08"	"4.63"	"3"	"2"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00298, Pf03946"	"6136"	"ENSG00000197958"	"RPL12"	"hsa:6136; P30050; Q5VVV2; Q6PB27"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"386.4"	"280.6"	"453.4"	"369.4"	"345.2"	"372.5"	"556.0"	"785.5"	"705.9"	"1501.9"	"2406.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P57772"	"Selenocysteine-specific elongation factor OS=Homo sapiens OX=9606 GN=EEFSEC PE=1 SV=4"	"0.000"	""	"3"	"2"	"4"	"2"	"596"	"65.3"	"8.35"	"531.32"	"4.62"	"2"	"2"	"protein metabolism;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009"	"60678"	"ENSG00000132394; ENSG00000284869"	"EEFSEC"	"hsa:60678; P57772; Q96HZ6"	""	"Selenocysteine synthesis"	"1"	"0"	"152.1"	"103.1"	"143.8"	"125.0"	"136.4"	"187.9"	"290.5"	"512.6"	"421.6"	"387.2"	"444.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96T23"	"Remodeling and spacing factor 1 OS=Homo sapiens OX=9606 GN=RSF1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1441"	"163.7"	"5.01"	"558.89"	"4.62"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00628, Pf15612"	"51773"	"ENSG00000048649"	"RSF1"	"hsa:51773; Q86X86; Q96T23; Q9H3L8; Q9NVZ8; Q9NYU0"	""	"Deposition of new CENPA-containing nucleosomes at the centromere"	"1"	"0"	"32.3"	"22.6"	"39.6"	"39.8"	"37.2"	"37.0"	"51.6"	"86.0"	"79.0"	"168.4"	"209.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y2Z0"	"Protein SGT1 homolog OS=Homo sapiens OX=9606 GN=SUGT1 PE=1 SV=3"	""	""	"6"	"1"	"1"	"1"	"365"	"41.0"	"5.16"	""	"4.61"	""	"1"	"cell cycle OR cell proliferation;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf04969, Pf05002"	"10910"	"ENSG00000165416"	"SUGT1"	"A2A303; hsa:10910; Q5JAK5; Q5TAM6; Q6VXY6; Q9Y2Z0"	"Nucleotide-binding oligomerization domain (NOD) pathway"	"The NLRP3 inflammasome; Purinergic signaling in leishmaniasis infection"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15182"	"Centrin-3 OS=Homo sapiens OX=9606 GN=CETN3 PE=1 SV=2"	"0.000"	""	"12"	"1"	"2"	"1"	"167"	"19.5"	"4.74"	"420.17"	"4.61"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf13499"	"1070"	"ENSG00000153140"	"CETN3"	"hsa:1070; O15182; Q53YD2; Q9BS23"	"Breast cancer pathway"	""	"1"	"0"	"15.3"	"10.3"	"23.1"	"16.8"	"19.8"	"29.7"	"44.6"	"98.6"	"108.8"	"227.3"	"270.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NWY4"	"Histone PARylation factor 1 OS=Homo sapiens OX=9606 GN=HPF1 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"346"	"39.4"	"6.80"	"562.07"	"4.59"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf10228"	"54969"	"ENSG00000056050"	"HPF1"	"hsa:54969; Q9NWY4"	""	""	"0"	"0"	"28.7"	"23.9"	"30.1"	"31.5"	"27.7"	"27.1"	"33.9"	"92.4"	"111.1"	"284.9"	"390.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"A8K8P3"	"Protein SFI1 homolog OS=Homo sapiens OX=9606 GN=SFI1 PE=1 SV=2"	""	""	"1"	"1"	"2"	"1"	"1242"	"147.6"	"10.81"	""	"4.59"	""	"1"	""	"cytosol;cytoskeleton"	"other molecular function"	""	"9814"	"ENSG00000198089"	"SFI1"	"A1L373; A1L387; A2A2L2; A8K8P3; B1AKL9; B5MDB7; B7Z1V6; B7Z8G3; B7ZBE2; B7ZBE3; hsa:9814; O60289; Q2TAN8; Q5W1B5; Q86TK0; Q8N4U8; Q8N8C1; Q8WU14"	""	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"7"	"0"	"211.6"	"89.9"	"309.0"	"255.0"	"232.0"	"235.0"	"288.0"	"294.1"	"315.4"	"377.5"	"314.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P08574"	"Cytochrome c1, heme protein, mitochondrial OS=Homo sapiens OX=9606 GN=CYC1 PE=1 SV=3"	""	""	"7"	"1"	"1"	"1"	"325"	"35.4"	"9.00"	""	"4.59"	""	"1"	"other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf02167"	"1537"	"ENSG00000179091"	"CYC1"	"hsa:1537; P08574; Q5U062; Q6FHS7"	"Nonalcoholic fatty liver disease; Mitochondrial complex III assembly"	"Respiratory electron transport; Mitochondrial protein import"	"4"	"0"	"29.6"	"24.3"	"26.1"	"27.7"	"27.7"	"27.1"	"39.4"	"58.8"	"52.3"	"112.1"	"121.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P82673"	"28S ribosomal protein S35, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS35 PE=1 SV=1"	"0.001"	""	"10"	"2"	"2"	"2"	"323"	"36.8"	"8.24"	"232.55"	"4.57"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf10213"	"60488"	"ENSG00000061794"	"MRPS35"	"hsa:60488; P82673; Q32LZ1; Q6P4C6; Q7L1M6; Q8NBP4; Q96AI0; Q9H044; Q9HC14; Q9P1R5"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"308.0"	"268.0"	"270.2"	"280.4"	"251.7"	"274.6"	"354.0"	"428.2"	"387.5"	"726.7"	"1227.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P48729"	"Casein kinase I isoform alpha OS=Homo sapiens OX=9606 GN=CSNK1A1 PE=1 SV=2"	""	""	"6"	"1"	"1"	"1"	"337"	"38.9"	"9.57"	""	"4.56"	""	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"1452"	"ENSG00000113712"	"CSNK1A1"	"D3DQG0; D3DQG1; hsa:1452; P48729; Q4JJA0; Q5U046; Q5U047; Q6FGA2; Q71TU5; Q96HD2; Q9UDK3"	"Alzheimer's disease and miRNA effects; T cell receptor and co-stimulatory signaling; Complement system; Wnt signaling pathway; Wnt/beta-catenin signaling pathway in leukemia; Regulation of Wnt / B-catenin signaling by small molecule compounds; Chromosomal and microsatellite instability in colorectal cancer ; Hedgehog signaling pathway; lncRNA in canonical Wnt signaling and colorectal cancer; Breast cancer pathway; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Influence of laminopathies on Wnt signaling; Overlap between signal transduction pathways contributing to LMNA laminopathies; Pleural mesothelioma; Alzheimer's disease; DYRK1A involvement regarding cell proliferation in brain development"	"Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Activation of SMO; Disassembly of the destruction complex and recruitment of AXIN to the membrane; Beta-catenin phosphorylation cascade; Signaling by GSK3beta mutants; CTNNB1 S33 mutants aren't phosphorylated; CTNNB1 S37 mutants aren't phosphorylated; CTNNB1 S45 mutants aren't phosphorylated; CTNNB1 T41 mutants aren't phosphorylated; APC truncation mutants have impaired AXIN binding; AXIN missense mutants destabilize the destruction complex; Truncations of AMER1 destabilize the destruction complex; Maturation of nucleoprotein"	"32"	"0"	"22.6"	"36.0"	"27.9"	"26.8"	"32.3"	"27.4"	"27.0"	"50.6"	"45.2"	"77.6"	"81.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UJA5"	"tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 OS=Homo sapiens OX=9606 GN=TRMT6 PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"497"	"55.8"	"7.55"	""	"4.56"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf04189"	"51605"	"ENSG00000089195"	"TRMT6"	"B4DUV6; hsa:51605; Q76P92; Q9BQV5; Q9UJA5; Q9ULR7; Q9Y2Z8"	""	"tRNA modification in the nucleus and cytosol"	"1"	"0"	"23.9"	"25.4"	"21.0"	"17.1"	"24.9"	"28.8"	"38.0"	"52.6"	"46.6"	"88.1"	"139.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15084"	"Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A OS=Homo sapiens OX=9606 GN=ANKRD28 PE=1 SV=5"	"0.000"	""	"1"	"1"	"2"	"1"	"1053"	"112.9"	"6.25"	"478.13"	"4.55"	"1"	"1"	""	"cytosol;nucleus"	""	"Pf00023, Pf13637"	"23243"	"ENSG00000206560"	"ANKRD28"	"B4DES5; hsa:23243; O15084; Q1WWL4; Q29RW6; Q3B857; Q6ULS0; Q6ZT57"	""	"Telomere Extension By Telomerase; COPII-mediated vesicle transport"	"2"	"0"	"9.3"	"3.3"	"18.3"	"9.8"	"9.9"	"8.6"	"11.1"	"27.8"	"25.8"	"66.5"	"96.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95166"	"Gamma-aminobutyric acid receptor-associated protein OS=Homo sapiens OX=9606 GN=GABARAP PE=1 SV=1"	"0.000"	""	"32"	"4"	"5"	"3"	"117"	"13.9"	"8.79"	"1291.69"	"4.55"	"4"	"1"	"cell-cell signaling;cell organization and biogenesis;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf02991"	"11337"	"ENSG00000170296"	"GABARAP"	"hsa:11337; O95166"	"2q37 copy number variation syndrome"	"Macroautophagy; TBC/RABGAPs"	"3"	"1"	"413.3"	"279.9"	"471.2"	"431.9"	"407.5"	"443.1"	"469.9"	"960.3"	"937.7"	"1720.7"	"2069.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P60953"	"Cell division control protein 42 homolog OS=Homo sapiens OX=9606 GN=CDC42 PE=1 SV=2"	"0.000"	""	"6"	"1"	"2"	"1"	"191"	"21.2"	"6.55"	"512.95"	"4.55"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00071"	"998"	"ENSG00000070831"	"CDC42"	"hsa:998; P21181; P25763; P60953; Q7L8R5; Q9UDI2"	"Androgen receptor signaling pathway; Target of rapamycin signaling; Integrin-mediated cell adhesion; RANKL/RANK signaling pathway; Leptin signaling pathway; Microtubule cytoskeleton regulation; Metastatic brain tumor; Pathogenic Escherichia coli infection; RalA downstream regulated genes; B cell receptor signaling pathway; AGE/RAGE pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Spinal cord injury; Focal adhesion; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Oxidative damage response; p38 MAPK signaling pathway; Ebola virus infection in host; Ras signaling; Pancreatic adenocarcinoma pathway; EGF/EGFR signaling pathway; Nonalcoholic fatty liver disease; Hippo signaling regulation pathways; 22q11.2 copy number variation syndrome; Gastrin signaling pathway; Regulation of actin cytoskeleton; G13 signaling pathway; Genetic causes of porto-sinusoidal vascular disease; 13q12.12 copy number variation; T-cell receptor signaling pathway; DNA damage response (only ATM dependent)"	"RHO GTPases Activate Formins; MAPK6/MAPK4 signaling; RHO GTPases activate IQGAPs; RAC1 GTPase cycle; RHOV GTPase cycle; RHOU GTPase cycle; VEGFA-VEGFR2 Pathway; RHOG GTPase cycle; EPHB-mediated forward signaling; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; CDC42 GTPase cycle; RHOQ GTPase cycle; RHO GTPases Activate WASPs and WAVEs; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOJ GTPase cycle; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; DCC mediated attractive signaling; GPVI-mediated activation cascade; Myogenesis; Factors involved in megakaryocyte development and platelet production; G beta:gamma signalling through CDC42; EGFR downregulation; RHO GTPases activate PAKs; Inactivation of CDC42 and RAC1; CD28 dependent Vav1 pathway; RHO GTPases activate KTN1"	"61"	"0"	"345.8"	"241.3"	"309.5"	"268.1"	"280.9"	"293.9"	"357.3"	"503.5"	"523.3"	"1111.7"	"1372.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3D8"	"Adenylate kinase isoenzyme 6 OS=Homo sapiens OX=9606 GN=AK6 PE=1 SV=1"	"0.000"	""	"9"	"1"	"2"	"1"	"172"	"20.0"	"4.58"	"441.15"	"4.55"	"1"	"1"	"other metabolic processes"	"cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf13238"	"102157402"	"ENSG00000085231; ENSG00000279247"	"AK6"	"A8MSZ6; hsa:102157402; Q5F2S9; Q9Y3D8"	""	"Interconversion of nucleotide di- and triphosphates"	"1"	"0"	"32.1"	"25.1"	"32.6"	"31.6"	"26.8"	"33.1"	"50.5"	"67.9"	"79.8"	"291.7"	"484.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P0C7P4"	"Putative cytochrome b-c1 complex subunit Rieske-like protein 1 OS=Homo sapiens OX=9606 GN=UQCRFS1P1 PE=5 SV=1"	"0.000"	""	"5"	"2"	"3"	"2"	"283"	"30.8"	"8.87"	"246.28"	"4.54"	"1"	"2"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00355, Pf02921, Pf09165"	""	""	"UQCRFS1P1"	"P0C7P4"	""	""	"0"	"0"	"111.3"	"115.6"	"83.1"	"95.9"	"92.3"	"92.1"	"122.2"	"175.2"	"159.0"	"276.9"	"361.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IWC1"	"MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"876"	"98.4"	"9.32"	"676.53"	"4.53"	"1"	"1"	"cell organization and biogenesis"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf05672"	"79649"	"ENSG00000129680"	"MAP7D3"	"A2A2J0; A6NCZ7; A6NHR4; B4DWD2; H7BY77; hsa:79649; Q5JXI5; Q5JXI6; Q6P2S1; Q8IWC1; Q9H9M8"	""	""	"0"	"0"	"120.0"	"103.0"	"122.9"	"125.6"	"124.0"	"116.6"	"144.3"	"167.7"	"169.2"	"197.7"	"198.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NRP0"	"Oligosaccharyltransferase complex subunit OSTC OS=Homo sapiens OX=9606 GN=OSTC PE=1 SV=1"	"0.000"	""	"8"	"1"	"2"	"1"	"149"	"16.8"	"9.13"	"371.30"	"4.53"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;ER/Golgi"	""	"Pf04756"	"58505"	"ENSG00000198856"	"OSTC"	"A8MYS2; B2R5H1; D6RH22; hsa:58505; Q9NRP0; Q9P075; Q9P1R4"	""	""	"0"	"0"	"35.6"	"27.2"	"34.7"	"38.4"	"37.7"	"36.6"	"41.8"	"113.5"	"130.7"	"281.0"	"384.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBE0"	"SUMO-activating enzyme subunit 1 OS=Homo sapiens OX=9606 GN=SAE1 PE=1 SV=1"	"0.000"	""	"5"	"2"	"3"	"2"	"346"	"38.4"	"5.30"	"255.09"	"4.53"	"1"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00899"	"10055"	"ENSG00000142230"	"SAE1"	"B2RDP5; B3KMQ2; F5GXX7; G3XAK6; hsa:10055; O95717; Q9P020; Q9UBE0"	""	"SUMO is conjugated to E1 (UBA2:SAE1); SUMO is transferred from E1 to E2 (UBE2I, UBC9)"	"2"	"0"	"17.0"	"16.8"	"20.6"	"12.9"	"16.1"	"11.6"	"19.2"	"35.0"	"32.0"	"81.8"	"169.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q15050"	"Ribosome biogenesis regulatory protein homolog OS=Homo sapiens OX=9606 GN=RRS1 PE=1 SV=2"	""	""	"7"	"1"	"1"	"1"	"365"	"41.2"	"10.70"	""	"4.53"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity"	"Pf04939"	"23212"	"ENSG00000179041"	"RRS1"	"hsa:23212; Q15050; Q9BUX8"	""	""	"0"	"0"	"6.2"	"3.6"	"7.2"	"5.7"	"6.7"	"8.4"	"10.9"	"14.7"	"14.9"	"29.8"	"42.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22830"	"Ferrochelatase, mitochondrial OS=Homo sapiens OX=9606 GN=FECH PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"423"	"47.8"	"8.73"	"364.19"	"4.52"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"other membranes;mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00762"	"2235"	"ENSG00000066926"	"FECH"	"A8KA72; hsa:2235; P22830; Q8IXN1; Q8NAN0"	"Hemesynthesis defects and porphyrias; Heme biosynthesis"	"Heme biosynthesis"	"3"	"0"	"21.5"	"16.5"	"33.7"	"42.6"	"24.1"	"28.5"	"31.9"	"79.8"	"89.9"	"245.7"	"477.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92558"	"Wiskott-Aldrich syndrome protein family member 1 OS=Homo sapiens OX=9606 GN=WASF1 PE=1 SV=1"	"0.000"	""	"4"	"2"	"3"	"2"	"559"	"61.6"	"6.46"	"612.65"	"4.51"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02205"	"8936"	"ENSG00000112290"	"WASF1"	"E1P5F2; hsa:8936; Q5SZK7; Q92558"	"VEGFA-VEGFR2 signaling; Regulation of actin cytoskeleton"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RAC1 GTPase cycle; RHO GTPases Activate WASPs and WAVEs; RAC3 GTPase cycle; VEGFA-VEGFR2 Pathway"	"8"	"0"	"53.1"	"47.0"	"42.1"	"43.4"	"40.4"	"42.2"	"67.1"	"145.4"	"147.4"	"272.1"	"365.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5TCQ9"	"Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAGI3 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1481"	"162.8"	"8.09"	"416.81"	"4.51"	"1"	"1"	"other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00397, Pf00595, Pf00625"	"260425"	"ENSG00000081026"	"MAGI3"	"A0A024R0E9; A0A024R0H3; hsa:260425; Q5TCQ8; Q5TCQ9; Q5TCR0; Q9H2V6; Q9H5Y8; Q9HBC4; Q9HCD8"	""	""	"0"	"0"	"23.9"	"27.4"	"29.0"	"30.0"	"28.2"	"31.1"	"35.0"	"76.8"	"73.8"	"172.6"	"185.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VYK3"	"Proteasome adapter and scaffold protein ECM29 OS=Homo sapiens OX=9606 GN=ECPAS PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1845"	"204.2"	"7.12"	"470.12"	"4.49"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response"	"cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf13001"	""	"ENSG00000136813"	"ECPAS"	"O15074; Q5VYK3; Q8WU82"	""	""	"0"	"0"	"9.1"	"7.0"	"11.3"	"8.8"	"10.1"	"8.6"	"14.4"	"36.5"	"36.3"	"122.1"	"143.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P04844"	"Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Homo sapiens OX=9606 GN=RPN2 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"631"	"69.2"	"5.69"	"505.08"	"4.49"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;ER/Golgi;nucleus;other cytoplasmic organelle"	"translation activity"	"Pf05817"	"6185"	"ENSG00000118705"	"RPN2"	"hsa:6185; P04844; Q5JYR6; Q6IBA5; Q96E21; Q9BUQ3; Q9UBE1"	"Proteasome degradation; N-glycan biosynthesis"	"SRP-dependent cotranslational protein targeting to membrane; Asparagine N-linked glycosylation; Maturation of spike protein"	"5"	"0"	"4.5"	"4.2"	"7.1"	"5.7"	"5.3"	"2.2"	"5.5"	"21.6"	"25.9"	"80.0"	"119.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VT06"	"Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"3117"	"350.7"	"6.33"	"548.72"	"4.48"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf01302, Pf14309"	"9857"	"ENSG00000135837"	"CEP350"	"hsa:9857; O75068; Q5VT06; Q8TDK3; Q8WY20"	"3q29 copy number variation syndrome"	""	"1"	"0"	"12.5"	"11.1"	"14.3"	"16.1"	"14.1"	"8.5"	"18.4"	"29.8"	"22.6"	"53.1"	"64.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49459"	"Ubiquitin-conjugating enzyme E2 A OS=Homo sapiens OX=9606 GN=UBE2A PE=1 SV=2"	"0.000"	""	"9"	"1"	"2"	"1"	"152"	"17.3"	"5.15"	"508.86"	"4.48"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00179"	"7319"	"ENSG00000077721"	"UBE2A"	"A6NFE9; A6NGR2; A6NMF5; B2R7R9; D3DWI1; hsa:7319; P49459; Q4TTG1; Q96FX4"	""	"E3 ubiquitin ligases ubiquitinate target proteins; Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Antigen processing: Ubiquitination & Proteasome degradation"	"3"	"0"	"29.0"	"23.9"	"38.3"	"43.9"	"42.8"	"36.8"	"45.2"	"80.3"	"78.6"	"180.8"	"219.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BRD0"	"BUD13 homolog OS=Homo sapiens OX=9606 GN=BUD13 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"619"	"70.5"	"9.86"	"541.46"	"4.48"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf09736"	"84811"	"ENSG00000137656"	"BUD13"	"A8K0S0; hsa:84811; Q96LS7; Q9BRD0"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"9.7"	"10.3"	"7.6"	"6.9"	"9.4"	"8.6"	"13.7"	"32.2"	"32.7"	"102.9"	"97.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2U8"	"Inner nuclear membrane protein Man1 OS=Homo sapiens OX=9606 GN=LEMD3 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"911"	"99.9"	"7.55"	"629.49"	"4.47"	"1"	"1"	"other biological processes"	"other membranes;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03020, Pf09402"	"23592"	"ENSG00000174106"	"LEMD3"	"hsa:23592; Q9NT47; Q9NYA5; Q9Y2U8"	"Envelope proteins and their potential roles in EDMD physiopathology"	"RND3 GTPase cycle; RND2 GTPase cycle; RAC1 GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOD GTPase cycle; RND1 GTPase cycle; Initiation of Nuclear Envelope (NE) Reformation; Depolymerization of the Nuclear Lamina"	"12"	"0"	"43.1"	"51.7"	"29.1"	"34.9"	"38.0"	"32.4"	"53.1"	"126.0"	"127.9"	"279.2"	"323.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BWW4"	"Single-stranded DNA-binding protein 3 OS=Homo sapiens OX=9606 GN=SSBP3 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"388"	"40.4"	"6.90"	"479.22"	"4.47"	"1"	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04503"	"23648"	"ENSG00000157216"	"SSBP3"	"A8K0A9; hsa:23648; Q5T860; Q5T861; Q9BTM0; Q9BWW3; Q9BWW4"	""	""	"0"	"0"	"46.4"	"35.1"	"45.2"	"47.7"	"44.1"	"50.9"	"51.5"	"109.9"	"114.9"	"273.4"	"395.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y4B4"	"Helicase ARIP4 OS=Homo sapiens OX=9606 GN=RAD54L2 PE=1 SV=4"	""	""	"1"	"1"	"1"	"1"	"1467"	"162.7"	"6.09"	""	"4.47"	""	"1"	"cell organization and biogenesis"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271"	"23132"	"ENSG00000164080"	"RAD54L2"	"hsa:23132; Q8TB57; Q9BV54; Q9Y4B4"	"DYRK1A involvement regarding cell proliferation in brain development"	""	"1"	"0"	"12.2"	"7.7"	"11.8"	"9.3"	"8.6"	"11.6"	"12.6"	"21.1"	"20.9"	"27.3"	"43.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P42696"	"RNA-binding protein 34 OS=Homo sapiens OX=9606 GN=RBM34 PE=1 SV=2"	""	""	"5"	"1"	"1"	"1"	"430"	"48.5"	"10.11"	""	"4.47"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"23029"	"ENSG00000188739"	"RBM34"	"A8K8J7; hsa:23029; P42696; Q8N2Z8; Q9H5A1"	""	""	"0"	"0"	"26.3"	"21.3"	"17.8"	"23.6"	"23.8"	"25.7"	"22.5"	"40.4"	"40.2"	"73.4"	"108.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35914"	"Hydroxymethylglutaryl-CoA lyase, mitochondrial OS=Homo sapiens OX=9606 GN=HMGCL PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"325"	"34.3"	"8.54"	"425.17"	"4.46"	"1"	"1"	"cell organization and biogenesis;other metabolic processes"	"cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00682"	"3155"	"ENSG00000117305"	"HMGCL"	"B4DUP4; B7UCC6; D3Y5K7; hsa:3155; P35914; Q6IBC0; Q96FP8"	"Amino acid metabolism"	"Peroxisomal protein import; Synthesis of Ketone Bodies"	"3"	"0"	"52.3"	"36.5"	"57.3"	"62.3"	"40.1"	"49.7"	"68.6"	"143.8"	"131.6"	"307.9"	"464.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P18077"	"60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A PE=1 SV=2"	"0.000"	""	"11"	"1"	"2"	"1"	"110"	"12.5"	"11.06"	"478.27"	"4.46"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01247"	"6165"	"ENSG00000182899"	"RPL35A"	"hsa:6165; P18077; Q08ES9; Q9BVN7"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"152.1"	"63.6"	"207.2"	"189.6"	"174.1"	"192.8"	"255.8"	"402.4"	"478.4"	"1040.8"	"1583.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96DT7"	"Zinc finger and BTB domain-containing protein 10 OS=Homo sapiens OX=9606 GN=ZBTB10 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"871"	"94.8"	"5.16"	"494.97"	"4.45"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00651, Pf13909"	"65986"	"ENSG00000205189"	"ZBTB10"	"A4FVD0; hsa:65986; Q86W96; Q8IXI9; Q96DT7; Q96MH9"	""	""	"0"	"0"	"52.7"	"37.4"	"49.8"	"50.4"	"47.0"	"51.4"	"64.8"	"89.2"	"91.8"	"142.9"	"184.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P26196"	"Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"483"	"54.4"	"8.66"	"571.61"	"4.45"	"1"	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"1656"	"ENSG00000110367"	"DDX6"	"hsa:1656; P26196; Q5D048"	""	"mRNA decay by 5' to 3' exoribonuclease"	"1"	"0"	"62.4"	"52.9"	"65.5"	"64.0"	"60.9"	"63.6"	"74.6"	"100.8"	"103.3"	"203.0"	"260.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H857"	"5'-nucleotidase domain-containing protein 2 OS=Homo sapiens OX=9606 GN=NT5DC2 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"520"	"60.7"	"6.77"	"541.83"	"4.43"	"1"	"1"	""	""	"other molecular function"	"Pf05761"	"64943"	"ENSG00000168268"	"NT5DC2"	"C9JTZ6; E9PAL9; hsa:64943; O95888; Q96C80; Q9H857; Q9H9Z8"	""	""	"0"	"0"	"18.1"	"11.2"	"20.1"	"14.3"	"16.5"	"18.5"	"26.9"	"44.2"	"41.1"	"104.1"	"121.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13011"	"Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial OS=Homo sapiens OX=9606 GN=ECH1 PE=1 SV=2"	"0.000"	""	"7"	"3"	"4"	"3"	"328"	"35.8"	"8.00"	"860.84"	"4.43"	"2"	"2"	"other metabolic processes"	"cytosol;mitochondrion;other cytoplasmic organelle"	"other molecular function"	"Pf00378"	"1891"	"ENSG00000104823; ENSG00000282853"	"ECH1"	"A8K745; hsa:1891; Q13011; Q8WVX0; Q96EZ9"	"Fatty acid biosynthesis; IL-18 signaling pathway"	"Peroxisomal protein import"	"3"	"0"	"133.2"	"111.0"	"111.4"	"127.7"	"125.8"	"126.5"	"163.4"	"368.8"	"357.1"	"1215.7"	"1904.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P28074"	"Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3"	"0.000"	""	"5"	"1"	"2"	"1"	"263"	"28.5"	"6.92"	"568.08"	"4.43"	"1"	"1"	"protein metabolism;other metabolic processes;stress response"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00227"	"5693"	"ENSG00000100804"	"PSMB5"	"B2R4N9; B4DUM9; D3DS43; E9PAV2; hsa:5693; P28074; Q16242; Q6PEW2; Q7Z3B5; Q86T01; Q9TNN9"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Asymmetric localization of PCP proteins; Degradation of DVL; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Regulation of expression of SLITs and ROBOs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Degradation of AXIN; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"62"	"0"	"4.4"	"2.8"	"3.8"	"4.1"	"3.0"	"0.0"	"3.3"	"10.0"	"10.8"	"24.0"	"52.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N5F7"	"NF-kappa-B-activating protein OS=Homo sapiens OX=9606 GN=NKAP PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"415"	"47.1"	"10.11"	"390.10"	"4.43"	"1"	"1"	"cell cycle OR cell proliferation;signal transduction;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf06047, Pf15692"	"79576"	"ENSG00000101882"	"NKAP"	"hsa:79576; Q6IPW6; Q8N5F7; Q96BQ2; Q9H638"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"51.5"	"34.9"	"58.5"	"54.5"	"52.1"	"51.6"	"63.8"	"84.0"	"94.7"	"177.5"	"266.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O00487"	"26S proteasome non-ATPase regulatory subunit 14 OS=Homo sapiens OX=9606 GN=PSMD14 PE=1 SV=1"	""	""	"11"	"1"	"1"	"1"	"310"	"34.6"	"6.52"	""	"4.42"	""	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf01398, Pf13012"	"10213"	"ENSG00000115233"	"PSMD14"	"B3KNW2; hsa:10213; O00176; O00487"	"Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Metalloprotease DUBs"	"64"	"0"	"4.9"	"3.2"	"4.1"	"5.2"	"6.8"	"4.2"	"4.8"	"12.6"	"9.1"	"36.0"	"65.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q06210"	"Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3"	"0.000"	""	"3"	"2"	"3"	"2"	"699"	"78.8"	"7.11"	"787.46"	"4.42"	"2"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol"	"other molecular function"	"Pf01380, Pf13522"	"2673"	"ENSG00000198380"	"GFPT1"	"hsa:2673; Q06210; Q53QE6; Q9BXF8"	"UDP-derived sugars synthesis in fibroblasts"	"XBP1(S) activates chaperone genes; Synthesis of UDP-N-acetyl-glucosamine; Defective GFPT1 causes CMSTA1"	"4"	"0"	"32.2"	"18.5"	"42.2"	"31.3"	"33.9"	"30.0"	"48.1"	"130.1"	"134.2"	"334.3"	"418.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13017"	"Rho GTPase-activating protein 5 OS=Homo sapiens OX=9606 GN=ARHGAP5 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1502"	"172.4"	"6.62"	"424.40"	"4.41"	"1"	"1"	"cell adhesion;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00071, Pf00620, Pf01846, Pf16512, Pf19518"	"394"	"ENSG00000100852"	"ARHGAP5"	"A1L375; A1L376; A8KAA1; D3DS89; D3DS90; hsa:394; Q05BE8; Q05BU8; Q13017; Q59ER0; Q6DHZ3"	"Focal adhesion"	"RHOC GTPase cycle; RND2 GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RHOG GTPase cycle; RAC3 GTPase cycle; RHOB GTPase cycle; RHOD GTPase cycle; RHOJ GTPase cycle; RHOF GTPase cycle; RND3 GTPase cycle; RND1 GTPase cycle"	"15"	"0"	"13.2"	"7.7"	"18.8"	"14.1"	"15.7"	"12.8"	"12.5"	"50.6"	"56.1"	"92.8"	"161.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P20674"	"Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A PE=1 SV=2"	"0.000"	""	"10"	"1"	"2"	"1"	"150"	"16.8"	"6.79"	"439.27"	"4.41"	"1"	"1"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf02284"	"9377"	"ENSG00000178741"	"COX5A"	"hsa:9377; P20674; P30045; Q8TB65"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex IV assembly; 5q35 copy number variation; Arachidonate epoxygenase / epoxide hydrolase"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"8"	"0"	"13.4"	"8.3"	"12.2"	"19.7"	"19.2"	"11.7"	"18.3"	"57.9"	"63.4"	"254.1"	"373.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BW92"	"Threonine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=TARS2 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"718"	"81.0"	"7.30"	"369.90"	"4.40"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00587, Pf02824, Pf03129, Pf07973"	"80222"	"ENSG00000143374"	"TARS2"	"hsa:80222; Q53GW7; Q96I50; Q9BW92; Q9H9V2"	""	"Mitochondrial tRNA aminoacylation"	"1"	"0"	"18.6"	"13.8"	"45.4"	"20.1"	"21.6"	"29.6"	"28.2"	"69.4"	"81.8"	"272.5"	"388.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q0JRZ9"	"F-BAR domain only protein 2 OS=Homo sapiens OX=9606 GN=FCHO2 PE=1 SV=2"	"0.000"	""	"2"	"2"	"3"	"1"	"810"	"88.9"	"6.86"	"252.42"	"4.40"	"1"	"2"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00611, Pf10291"	"115548"	"ENSG00000157107"	"FCHO2"	"A8K6W7; B2RNQ9; B4DHK0; E9PG79; hsa:115548; Q0JRZ9; Q0JTJ3; Q96CF5"	""	"Cargo recognition for clathrin-mediated endocytosis"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5Q8"	"General transcription factor 3C polypeptide 5 OS=Homo sapiens OX=9606 GN=GTF3C5 PE=1 SV=2"	"0.000"	""	"7"	"3"	"4"	"3"	"519"	"59.5"	"6.90"	"1004.58"	"4.40"	"3"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09734, Pf17682"	"9328"	"ENSG00000148308"	"GTF3C5"	"A6NI44; A6NJB9; hsa:9328; Q5T7U2; Q5T7U3; Q8N2U7; Q8N857; Q96GD9; Q9H4P2; Q9Y5Q8"	""	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter"	"3"	"0"	"107.4"	"74.1"	"121.5"	"112.8"	"118.8"	"96.9"	"126.4"	"242.0"	"225.7"	"583.7"	"908.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P53355"	"Death-associated protein kinase 1 OS=Homo sapiens OX=9606 GN=DAPK1 PE=1 SV=6"	"0.000"	""	"2"	"2"	"3"	"2"	"1430"	"159.9"	"6.83"	"1038.47"	"4.39"	"2"	"1"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00023, Pf00069, Pf00531"	"1612"	"ENSG00000196730"	"DAPK1"	"B7ZLD2; B7ZLE7; hsa:1612; P53355; Q14CQ7; Q1W5W0; Q68CP8; Q6ZRZ3; Q9BTL8"	"Bladder cancer; Netrin-UNC5B signaling pathway"	"Caspase activation via Dependence Receptors in the absence of ligand"	"3"	"0"	"70.5"	"47.1"	"68.3"	"56.3"	"48.3"	"50.2"	"75.8"	"92.9"	"94.7"	"138.3"	"151.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H2W6"	"39S ribosomal protein L46, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL46 PE=1 SV=1"	"0.000"	""	"8"	"2"	"3"	"2"	"279"	"31.7"	"7.05"	"614.60"	"4.39"	"2"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf11788"	"26589"	"ENSG00000259494"	"MRPL46"	"B2RD75; hsa:26589; Q9H2W6; Q9HBU8"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"285.0"	"223.4"	"267.5"	"243.5"	"243.5"	"262.2"	"339.4"	"468.9"	"425.2"	"880.3"	"1091.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9ULD4"	"Bromodomain and PHD finger-containing protein 3 OS=Homo sapiens OX=9606 GN=BRPF3 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"1205"	"135.7"	"6.58"	""	"4.39"	""	"1"	"cell organization and biogenesis;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00439, Pf00855, Pf10513, Pf13831, Pf13832"	"27154"	"ENSG00000096070"	"BRPF3"	"A6ND56; A6NJE2; B7ZLN5; E7EX85; hsa:27154; Q17RB6; Q5R3K8; Q9ULD4"	""	"HATs acetylate histones; Platelet degranulation ; Regulation of TP53 Activity through Acetylation"	"3"	"0"	"18.5"	"12.3"	"16.3"	"13.8"	"18.7"	"11.2"	"17.5"	"30.3"	"23.9"	"40.5"	"51.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P07948"	"Tyrosine-protein kinase Lyn OS=Homo sapiens OX=9606 GN=LYN PE=1 SV=3"	""	""	"2"	"1"	"1"	"1"	"512"	"58.5"	"7.11"	""	"4.38"	""	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;kinase activity;other molecular function"	"Pf00017, Pf00018, Pf07714"	"4067"	"ENSG00000254087"	"LYN"	"A0AVQ5; hsa:4067; P07948"	"IL-5 signaling pathway; RANKL/RANK signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; B cell receptor signaling pathway; IL-3 signaling pathway; Kit receptor signaling pathway; Chemokine signaling pathway; Microglia pathogen phagocytosis pathway; GDNF signaling"	"FCGR activation; FCGR3A-mediated IL10 synthesis; FCGR3A-mediated phagocytosis; Regulation of signaling by CBL; EPHB-mediated forward signaling; Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants; Regulation of KIT signaling; EPH-ephrin mediated repulsion of cells; EPHA-mediated growth cone collapse; Signaling by CSF1 (M-CSF) in myeloid cells; CD28 co-stimulation; PECAM1 interactions; CTLA4 inhibitory signaling; Role of LAT2/NTAL/LAB on calcium mobilization; FCERI mediated MAPK activation; FCERI mediated Ca+2 mobilization; FCERI mediated NF-kB activation; CD22 mediated BCR regulation; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Erythropoietin activates Phosphoinositide-3-kinase (PI3K); GPVI-mediated activation cascade; Cyclin D associated events in G1; Growth hormone receptor signaling; Inactivation of CSF3 (G-CSF) signaling; Erythropoietin activates Phospholipase C gamma (PLCG); Erythropoietin activates STAT5; Erythropoietin activates RAS; Platelet Adhesion to exposed collagen; CD209 (DC-SIGN) signaling; Dectin-2 family"	"45"	"0"	"78.5"	"47.1"	"96.4"	"72.5"	"84.5"	"70.2"	"87.4"	"161.9"	"163.8"	"368.1"	"543.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P37198"	"Nuclear pore glycoprotein p62 OS=Homo sapiens OX=9606 GN=NUP62 PE=1 SV=3"	"0.000"	""	"4"	"2"	"3"	"2"	"522"	"53.2"	"5.31"	"681.74"	"4.38"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"other membranes;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf05064"	"23636"	"ENSG00000213024"	"NUP62"	"B3KWU5; hsa:23636; P37198; Q503A4; Q6GTM2; Q96C43; Q9NSL1"	"7q11.23 copy number variation syndrome"	"Regulation of HSF1-mediated heat shock response; Nuclear Pore Complex (NPC) Disassembly; HCMV Late Events; HCMV Early Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Postmitotic nuclear pore complex (NPC) reformation"	"30"	"0"	"164.3"	"104.2"	"155.5"	"153.6"	"114.9"	"128.0"	"180.0"	"291.1"	"297.7"	"623.0"	"932.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P1X5"	"Transcription initiation factor TFIID subunit 2 OS=Homo sapiens OX=9606 GN=TAF2 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"1199"	"136.9"	"8.19"	"501.82"	"4.37"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	""	"6873"	"ENSG00000064313"	"TAF2"	"B2RE82; hsa:6873; O43487; O43604; O60668; Q6P1X5; Q86WW7; Q8IWK4"	""	"RNA Polymerase II Pre-transcription Events; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; Regulation of TP53 Activity through Phosphorylation; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation"	"9"	"0"	"13.4"	"7.9"	"11.4"	"11.0"	"15.1"	"9.3"	"17.9"	"28.7"	"33.2"	"63.8"	"97.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8WZ42"	"Titin OS=Homo sapiens OX=9606 GN=TTN PE=1 SV=4"	""	""	"0"	"2"	"2"	"2"	"34350"	"3813.7"	"6.35"	""	"4.37"	""	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus"	"cytoskeletal activity;kinase activity;other molecular function"	"Pf00041, Pf00069, Pf02818, Pf07679, Pf09042, Pf18362"	"7273"	"ENSG00000155657"	"TTN"	"A6NKB1; E7EQE6; E7ET18; hsa:7273; K7ENY1; Q10465; Q10466; Q15598; Q2XUS3; Q32Q60; Q4U1Z6; Q4ZG20; Q6NSG0; Q6PDB1; Q6PJP0; Q7KYM2; Q7KYN4; Q7KYN5; Q7LDM3; Q7Z2X3; Q8TCG8; Q8WZ42; Q8WZ51; Q8WZ52; Q8WZ53; Q8WZB3; Q92761; Q92762; Q9UD97; Q9UP84; Q9Y6L9"	"Striated muscle contraction pathway; Cardiomyocyte signaling pathways converging on Titin"	"Platelet degranulation ; Striated Muscle Contraction"	"4"	"0"	"228.5"	"203.1"	"158.1"	"163.3"	"136.0"	"161.2"	"226.3"	"589.1"	"672.6"	"1204.8"	"1298.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5A7"	"NEDD8 ultimate buster 1 OS=Homo sapiens OX=9606 GN=NUB1 PE=1 SV=2"	"0.000"	""	"3"	"2"	"3"	"1"	"615"	"70.5"	"5.96"	"580.33"	"4.36"	"2"	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus"	""	"Pf00627, Pf18037"	"51667"	"ENSG00000013374"	"NUB1"	"hsa:51667; O95422; Q75MR9; Q8IX22; Q9BXR2; Q9Y5A7"	""	""	"0"	"0"	"13.0"	"12.5"	"18.3"	"16.0"	"18.5"	"22.7"	"19.3"	"80.3"	"67.0"	"276.3"	"488.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKJ3"	"G patch domain-containing protein 8 OS=Homo sapiens OX=9606 GN=GPATCH8 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1502"	"164.1"	"8.66"	"343.41"	"4.36"	"1"	"1"	""	"nucleus"	"other molecular function"	"Pf01585, Pf12171"	"23131"	"ENSG00000186566"	"GPATCH8"	"B9EGP9; hsa:23131; O60300; Q8TB99; Q9UKJ3"	""	""	"0"	"0"	"52.7"	"37.7"	"59.8"	"57.4"	"48.7"	"44.3"	"54.3"	"75.5"	"77.8"	"143.4"	"201.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86TV6"	"Tetratricopeptide repeat protein 7B OS=Homo sapiens OX=9606 GN=TTC7B PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"843"	"94.1"	"6.89"	"548.60"	"4.36"	"1"	"1"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol"	""	"Pf12895, Pf13181, Pf13424, Pf19440"	"145567"	"ENSG00000165914"	"TTC7B"	"hsa:145567; Q86TV6; Q86U24; Q86VT3"	""	""	"0"	"0"	"14.4"	"15.6"	"22.0"	"21.6"	"20.7"	"15.2"	"26.0"	"72.7"	"94.9"	"203.3"	"269.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H773"	"dCTP pyrophosphatase 1 OS=Homo sapiens OX=9606 GN=DCTPP1 PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"170"	"18.7"	"5.03"	"473.95"	"4.35"	"1"	"1"	"DNA metabolism;other metabolic processes;stress response"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf12643"	"79077"	"ENSG00000179958"	"DCTPP1"	"hsa:79077; Q9H773"	"Pyrimidine metabolism"	"Interconversion of nucleotide di- and triphosphates"	"2"	"0"	"40.2"	"38.3"	"47.5"	"44.4"	"35.0"	"30.5"	"60.6"	"94.6"	"104.3"	"181.6"	"263.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H6F5"	"Coiled-coil domain-containing protein 86 OS=Homo sapiens OX=9606 GN=CCDC86 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"360"	"40.2"	"10.33"	"487.36"	"4.34"	"1"	"1"	""	"nucleus;other cell component"	""	"Pf03879"	"79080"	"ENSG00000110104"	"CCDC86"	"B4DY99; hsa:79080; Q9H6F5"	""	""	"0"	"0"	"15.1"	"11.2"	"9.4"	"11.1"	"12.3"	"11.3"	"18.2"	"13.9"	"16.6"	"26.6"	"50.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NQC8"	"Intraflagellar transport protein 46 homolog OS=Homo sapiens OX=9606 GN=IFT46 PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"304"	"34.3"	"4.54"	"461.73"	"4.34"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"cytoskeleton;other cell component"	""	"Pf12317"	"56912"	"ENSG00000118096"	"IFT46"	"A8K0F6; hsa:56912; Q9H6V5; Q9NQC8"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein; Genes related to primary cilium development (based on CRISPR)"	"Intraflagellar transport"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P84101"	"Small EDRK-rich factor 2 OS=Homo sapiens OX=9606 GN=SERF2 PE=1 SV=1"	"0.000"	""	"17"	"1"	"3"	"1"	"59"	"6.9"	"10.45"	"667.41"	"4.33"	"1"	"1"	"other biological processes"	"cytosol;nucleus"	""	"Pf04419"	"10169"	"ENSG00000140264"	"SERF2"	"A6NL45; B5MCG1; B9A026; hsa:10169; O75918; O88891; P84101; Q9BZH7"	""	""	"0"	"0"	"107.6"	"103.7"	"176.7"	"219.1"	"188.4"	"177.9"	"222.9"	"337.6"	"314.5"	"364.0"	"409.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N122"	"Regulatory-associated protein of mTOR OS=Homo sapiens OX=9606 GN=RPTOR PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1335"	"148.9"	"6.89"	"424.88"	"4.32"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00400, Pf02985, Pf14538"	"57521"	"ENSG00000141564"	"RPTOR"	"B2RN36; C6KEF2; F5H7J5; hsa:57521; Q8N122; Q8N4V9; Q8TB32; Q9P2P3"	"AMP-activated protein kinase signaling; Target of rapamycin signaling; PI3K-AKT-mTOR signaling pathway and therapeutic opportunities in prostate cancer; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Clear cell renal cell carcinoma pathways; PI3K-Akt signaling pathway; Thermogenesis; Synaptic signaling pathways associated with autism spectrum disorder; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Head and neck squamous cell carcinoma; Thyroid hormones production and peripheral downstream signaling effects; IL-18 signaling pathway; CAMKK2 pathway; Autophagy; p53 transcriptional gene network; Pleural mesothelioma; Network map of SARS-CoV-2 signaling pathway; GDNF signaling; DYRK1A involvement regarding cell proliferation in brain development; JAK-STAT signaling in the regulation of Beta-cells; Interferon type I signaling pathways"	"Regulation of PTEN gene transcription; TP53 Regulates Metabolic Genes; mTORC1-mediated signalling; Amino acids regulate mTORC1; Macroautophagy; Energy dependent regulation of mTOR by LKB1-AMPK; HSF1-dependent transactivation"	"33"	"0"	"13.0"	"15.4"	"18.0"	"20.0"	"15.8"	"13.3"	"23.5"	"38.4"	"47.1"	"132.7"	"170.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14919"	"Dr1-associated corepressor OS=Homo sapiens OX=9606 GN=DRAP1 PE=1 SV=3"	"0.000"	""	"6"	"1"	"2"	"1"	"205"	"22.3"	"5.17"	"303.55"	"4.32"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00808"	"10589"	"ENSG00000175550"	"DRAP1"	"hsa:10589; Q13448; Q14919"	""	"Signaling by NODAL; Signaling by Activin"	"2"	"0"	"43.0"	"33.9"	"49.9"	"42.1"	"50.2"	"47.4"	"54.3"	"104.9"	"101.6"	"289.6"	"623.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WUR7"	"UPF0235 protein C15orf40 OS=Homo sapiens OX=9606 GN=C15orf40 PE=1 SV=2"	"0.000"	""	"14"	"2"	"3"	"2"	"153"	"16.3"	"9.83"	"721.58"	"4.31"	"2"	"1"	""	"other cell component"	""	"Pf02594"	"123207"	"ENSG00000169609"	"C15orf40"	"A6NIC9; B2R5E7; F5GX92; F8WD31; G5EA00; hsa:123207; Q8WUR7"	"15q25 copy number variation"	""	"1"	"0"	"168.4"	"122.3"	"169.0"	"133.1"	"147.6"	"152.1"	"202.8"	"448.9"	"434.4"	"673.4"	"752.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14694"	"Ubiquitin carboxyl-terminal hydrolase 10 OS=Homo sapiens OX=9606 GN=USP10 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"798"	"87.1"	"5.31"	"496.67"	"4.31"	"1"	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00443, Pf07145"	"9100"	"ENSG00000103194"	"USP10"	"B2RDJ8; B4DS84; hsa:9100; Q14694; Q9BWG7; Q9NSL7"	"VEGFA-VEGFR2 signaling"	"Ub-specific processing proteases; Termination of translesion DNA synthesis"	"3"	"0"	"11.8"	"8.3"	"15.3"	"12.3"	"9.9"	"9.2"	"15.7"	"25.3"	"26.8"	"61.2"	"73.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6IBW4"	"Condensin-2 complex subunit H2 OS=Homo sapiens OX=9606 GN=NCAPH2 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"605"	"68.2"	"4.74"	"512.70"	"4.30"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf06278, Pf16858, Pf16869"	"29781"	"ENSG00000025770"	"NCAPH2"	"B7WPH1; hsa:29781; O43788; Q13391; Q6IBW4; Q96C14; Q96GJ0; Q9BQ71; Q9BUT3; Q9BVD1"	"IL-18 signaling pathway"	"Condensation of Prophase Chromosomes"	"2"	"0"	"72.9"	"81.0"	"78.8"	"71.1"	"77.4"	"71.6"	"95.7"	"135.0"	"121.8"	"205.2"	"299.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P015"	"39S ribosomal protein L15, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL15 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"296"	"33.4"	"10.01"	"469.40"	"4.29"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00828"	"29088"	"ENSG00000137547"	"MRPL15"	"hsa:29088; Q96Q54; Q9H0Y1; Q9P015"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"120.1"	"100.6"	"117.4"	"113.7"	"108.9"	"123.5"	"148.8"	"203.0"	"209.3"	"436.4"	"806.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UPQ9"	"Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens OX=9606 GN=TNRC6B PE=1 SV=4"	""	""	"1"	"1"	"1"	"1"	"1833"	"193.9"	"6.76"	""	"4.27"	""	"1"	"other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf10427, Pf16608"	"23112"	"ENSG00000100354"	"TNRC6B"	"B0QY73; B0QY78; B4DGC0; hsa:23112; Q5TH52; Q8TBX2; Q9UPQ9"	""	"Oxidative Stress Induced Senescence; MAPK6/MAPK4 signaling; Estrogen-dependent gene expression; Pre-NOTCH Transcription and Translation; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; TP53 Regulates Metabolic Genes; Oncogene Induced Senescence; Transcriptional Regulation by VENTX; Ca2+ pathway; Regulation of MECP2 expression and activity; NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux; Regulation of RUNX1 Expression and Activity; Regulation of CDH11 mRNA translation by microRNAs; Regulation of NPAS4 mRNA translation; Post-transcriptional silencing by small RNAs; Competing endogenous RNAs (ceRNAs) regulate PTEN translation"	"18"	"0"	"6.9"	"0.0"	"4.2"	"4.1"	"6.5"	"3.6"	"11.0"	"13.0"	"12.2"	"29.8"	"44.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z2Z2"	"Elongation factor-like GTPase 1 OS=Homo sapiens OX=9606 GN=EFL1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"1120"	"125.4"	"5.91"	"398.04"	"4.27"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00009, Pf00679, Pf14492"	"79631"	"ENSG00000140598"	"EFL1"	"A6NKY5; B7Z6I0; hsa:79631; Q7Z2Z2; Q9H8Z6"	"Genetic causes of porto-sinusoidal vascular disease"	""	"1"	"0"	"3.0"	"2.8"	"5.4"	"7.3"	"4.3"	"5.0"	"2.6"	"27.7"	"22.2"	"248.2"	"390.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9ULX6"	"A-kinase anchor protein 8-like OS=Homo sapiens OX=9606 GN=AKAP8L PE=1 SV=4"	"0.000"	""	"2"	"1"	"2"	"1"	"646"	"71.6"	"5.05"	"383.10"	"4.27"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04988"	"26993"	"ENSG00000011243"	"AKAP8L"	"B4DJ74; B5BU90; hsa:26993; O94792; Q96J58; Q9NRQ0; Q9UGM0; Q9ULX6"	""	"Formation of WDR5-containing histone-modifying complexes"	"1"	"0"	"52.9"	"24.4"	"49.5"	"48.5"	"40.4"	"49.9"	"64.6"	"127.8"	"115.3"	"331.9"	"467.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96FK6"	"WD repeat-containing protein 89 OS=Homo sapiens OX=9606 GN=WDR89 PE=2 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"387"	"43.2"	"6.13"	"568.33"	"4.25"	"1"	"1"	"developmental processes"	""	""	"Pf00400"	"112840"	"ENSG00000140006"	"WDR89"	"hsa:112840; Q96FK6"	""	""	"0"	"0"	"30.1"	"21.0"	"33.1"	"29.8"	"30.1"	"28.0"	"40.8"	"117.7"	"108.2"	"518.9"	"581.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q07866"	"Kinesin light chain 1 OS=Homo sapiens OX=9606 GN=KLC1 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"573"	"65.3"	"6.20"	"525.09"	"4.24"	"1"	"1"	"cell adhesion;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf00515, Pf13374, Pf13424"	"3831"	"ENSG00000126214"	"KLC1"	"A6NF62; F8VTM4; hsa:3831; Q07866; Q7RTM2; Q7RTM3; Q7RTM5; Q7RTP9; Q7RTQ3; Q7RTQ5; Q7RTQ6; Q86SF5; Q86TF5; Q86V74; Q86V75; Q86V76; Q86V77; Q86V78; Q86V79; Q96H62"	"Alzheimer's disease and miRNA effects; IL-18 signaling pathway; Alzheimer's disease"	"COPI-dependent Golgi-to-ER retrograde traffic; MHC class II antigen presentation; Kinesins; Signaling by ALK fusions and activated point mutants; RHO GTPases activate KTN1"	"8"	"0"	"31.1"	"27.9"	"38.5"	"34.7"	"31.4"	"31.3"	"44.6"	"118.4"	"120.3"	"351.6"	"443.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P00338"	"L-lactate dehydrogenase A chain OS=Homo sapiens OX=9606 GN=LDHA PE=1 SV=2"	"0.000"	""	"5"	"2"	"4"	"2"	"332"	"36.7"	"8.27"	"556.18"	"4.23"	"2"	"2"	"other metabolic processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00056, Pf02866"	"3939"	"ENSG00000134333; ENSG00000288299"	"LDHA"	"B4DKQ2; B7Z5E3; D3DQY3; F8W819; hsa:3939; P00338; Q53G53; Q6IBM7; Q6ZNV1; Q9UDE8; Q9UDE9"	"Cori cycle; HIF1A and PPARG regulation of glycolysis; Photodynamic therapy-induced HIF-1 survival signaling; VEGFA-VEGFR2 signaling; Amino acid metabolism; Clear cell renal cell carcinoma pathways; PI3K/AKT/mTOR - vitamin D3 signaling; Metabolic reprogramming in colon cancer; Aerobic glycolysis; Glycolysis in senescence; Orexin receptor pathway; CCL18 signaling pathway; Glucose metabolism in triple-negative breast cancer cells; Warburg effect modulated by deubiquitinating enzymes and their substrates; Lactate shuttle in glial cells; Glycolysis and gluconeogenesis; A network map of Macrophage-stimulating protein (MSP) signaling; Metabolic Epileptic Disorders"	"Pyruvate metabolism"	"19"	"0"	"27.9"	"20.6"	"35.7"	"31.8"	"20.5"	"28.6"	"27.9"	"46.2"	"50.0"	"79.9"	"127.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8TF76"	"Serine/threonine-protein kinase haspin OS=Homo sapiens OX=9606 GN=HASPIN PE=1 SV=3"	""	""	"3"	"1"	"1"	"1"	"798"	"88.4"	"9.16"	""	"4.23"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf12330"	"83903"	"ENSG00000177602"	"HASPIN"	"hsa:83903; Q5U5K3; Q8TF76; Q96MN1; Q9BXS7"	""	""	"0"	"0"	"15.9"	"9.3"	"15.1"	"16.6"	"15.9"	"15.6"	"20.0"	"36.5"	"33.7"	"79.6"	"85.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14949"	"Cytochrome b-c1 complex subunit 8 OS=Homo sapiens OX=9606 GN=UQCRQ PE=1 SV=4"	"0.000"	""	"13"	"2"	"2"	"2"	"82"	"9.9"	"10.08"	"382.22"	"4.22"	"1"	"1"	"other metabolic processes;developmental processes"	"other membranes;mitochondrion"	""	"Pf02939"	"27089"	"ENSG00000164405"	"UQCRQ"	"hsa:27089; O14949; Q5FVE2; Q9BV88; Q9T2V7"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex III assembly"	"Respiratory electron transport"	"4"	"0"	"188.3"	"109.8"	"186.0"	"192.0"	"167.1"	"176.3"	"215.2"	"332.5"	"319.7"	"577.0"	"638.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H0W8"	"Protein SMG9 OS=Homo sapiens OX=9606 GN=SMG9 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"520"	"57.6"	"7.01"	"581.39"	"4.22"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes"	"cytosol"	"other molecular function"	"Pf10220"	"56006"	"ENSG00000105771"	"SMG9"	"hsa:56006; O60429; Q9H0W8; Q9H9A9"	""	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	"1"	"0"	"21.2"	"21.7"	"17.9"	"12.6"	"18.8"	"14.8"	"20.0"	"30.6"	"21.3"	"43.6"	"67.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P27635"	"60S ribosomal protein L10 OS=Homo sapiens OX=9606 GN=RPL10 PE=1 SV=4"	"0.000"	""	"5"	"1"	"2"	"1"	"214"	"24.6"	"10.08"	"491.04"	"4.22"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00252"	"100137264; 100146244; 100172946; 100415355; 100468790; 100724614; 100982236; 101083663; 101136536; 101344695; 101444008; 101539056; 101690567; 101867181; 101975002; 102028809; 102257301; 102442647; 102878669; 102890423; 102923570; 102957760; 103127392; 103211225; 103250904; 103731218; 104667036; 104872587; 105294701; 105302495; 105467951; 105521640; 105579731; 105727260; 105824536; 105867804; 106000161; 107160308; 108513162; 108518769; 109696857; 110954; 465944; 700795; 81764"	"ENSAMEG00000000227; ENSANAG00000036053; ENSCAFG00020009114; ENSCAFG00030015144; ENSCAFG00040021422; ENSCAFG00845028627; ENSCANG00000032226; ENSCATG00000030970; ENSCCAG00000024992; ENSCGRG00001008387; ENSCJAG00000011822; ENSCLAG00000003108; ENSCPOG00000002355; ENSECAG00000017154; ENSFCAG00000011395; ENSGGOG00000000131; ENSLCNG00005021252; ENSMFAG00000040824; ENSMLUG00000014337; ENSMMMG00000014279; ENSMMUG00000005494; ENSMNEG00000038094; ENSMPUG00000009320; ENSMUSG00000008682; ENSMUSG00000058443; ENSNGAG00000023746; ENSNLEG00000028143; ENSNVIG00000023818; ENSPANG00000008309; ENSPCOG00000027122; ENSPPAG00000034160; ENSPPYG00000020874; ENSPSMG00000015404; ENSPTIG00000005599; ENSPTRG00000043378; ENSRBIG00000042996; ENSRNOG00000056765; ENSRROG00000019247; ENSSSUG00005010590; ENSSTOG00000011857; ENSTGEG00000012563; ENSUAMG00000020454; ENSUMAG00000019583; ENSUPAG00010000252"	"LOC100768740; LOC101344695; LOC105294701; LOC112632580; Rpl10; RPL10"	"A0A091D943; A0A1S3APJ4; A0A1S3GPT7; A0A1U7SU42; A0A250YCK6; A0A286XQR8; A0A2I3FV08; A0A2J8IN69; A0A2J8RLU6; A0A2K5EV78; A0A2K5ILK8; A0A2K5LLF2; A0A2K5QER4; A0A2K5U275; A0A2K6D043; A0A2K6GRP4; A0A2K6MTH0; A0A2K6NK39; A0A2R9B361; A0A2Y9G5G6; A0A384DKX1; A0A3Q0CF07; A0A3Q7NJC4; A0A452S2Z9; A0A485PEW4; A0A667IJV2; A0A673U4F8; A0A6D2WIN2; A0A6D2XTB8; A0A6I9ME29; A0A6J0A9X4; A0A6J2E7G1; A0A6J3GU06; A0A6P3QFP2; A0A6P5P1X6; A0A6P6DLY1; A0A7J7YFN8; A0A7J8J7V5; A0A822A0T4; A0A8B7B976; A0A8B7FW91; A0A8C0K7J7; A0A8C0TBM4; A0A8C2LMI8; A0A8C2UVN1; A0A8C5ZPE8; A0A8C6S1T7; A0A8C7BXJ2; A0A8C8ZPD3; A0A8C9J452; A0A8D2F5T2; A0A8D2GF85; A0A8I3PXJ3; A0A8J8XDM4; A0A8M1M1S6; A0A9B0U593; A2AM97; A6KRS1; A9CB60; aju:106987320; aml:100468790; B0KWW6; B1MTV1; B3RFD9; C3PT02; cang:105521640; caty:105579731; ccan:109696857; cpoc:100724614; csyr:103250904; D3YC00; dnm:101444008; dord:106000161; ecb:100146244; F7AYR2; F7GKJ8; fca:101083663; G1PPT9; G2HFW2; G3S9Q9; G7Q3B3; ggo:101136536; H2PX84; I2CYS4; I3MI39; L5KDV0; L8Y8T7; M3WF14; M3YD39; mcal:110286529; mcc:700795; mcf:101867181; mlf:102442647; mmu:110954; mmur:105867804; mni:105467951; mpuf:101690567; myb:102257301; nsu:110578606; P45634; pale:102878669; pale:102890423; panu:100137264; pcoq:105824536; pps:100982236; ptg:102957760; ptr:465944; pvp:105294701; pvp:105302495; Q569M8; Q5M9K8; Q6PDV7; Q6ZWV3; rbb:108513162; rbb:108518769; rno:81764; rro:104667036; S7NR49; sara:101539056; tmu:101344695; umr:103679662; zca:113931110"	"Cytoplasmic ribosomal proteins"	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; SRP-dependent cotranslational protein targeting to membrane; Major pathway of rRNA processing in the nucleolus and cytosol; L13a-mediated translational silencing of Ceruloplasmin expression; SRP-dependent cotranslational protein targeting to membrane; Major pathway of rRNA processing in the nucleolus and cytosol; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	"15"	"0"	"68.2"	"55.5"	"71.6"	"72.3"	"75.2"	"54.2"	"88.0"	"126.4"	"113.7"	"216.4"	"338.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14699"	"Raftlin OS=Homo sapiens OX=9606 GN=RFTN1 PE=1 SV=4"	"0.000"	""	"2"	"1"	"2"	"1"	"578"	"63.1"	"5.67"	"434.22"	"4.22"	"1"	"1"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity"	"Pf15250"	"23180"	"ENSG00000131378"	"RFTN1"	"hsa:23180; Q0D2G0; Q14699; Q496Y2; Q4QQI7; Q5JB48; Q7Z7P2"	""	""	"0"	"0"	"69.7"	"59.2"	"68.9"	"66.2"	"57.4"	"62.1"	"85.1"	"307.0"	"324.4"	"740.5"	"891.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P266"	"Junctional protein associated with coronary artery disease OS=Homo sapiens OX=9606 GN=JCAD PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1359"	"148.3"	"7.09"	"496.96"	"4.22"	"1"	"1"	"cell adhesion;other biological processes"	"plasma membrane;other membranes;other cell component"	""	"Pf15351"	"57608"	"ENSG00000165757"	"JCAD"	"hsa:57608; Q5HYA7; Q5T992; Q86WZ9; Q9BYJ2; Q9P266"	""	""	"0"	"0"	"17.8"	"12.3"	"26.5"	"18.8"	"22.1"	"13.0"	"28.3"	"36.8"	"42.9"	"66.6"	"95.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q01664"	"Transcription factor AP-4 OS=Homo sapiens OX=9606 GN=TFAP4 PE=1 SV=2"	""	""	"7"	"1"	"1"	"1"	"338"	"38.7"	"5.87"	""	"4.19"	""	"1"	"cell organization and biogenesis;stress response;signal transduction;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00010"	"7023"	"ENSG00000090447"	"TFAP4"	"hsa:7023; O60409; Q01664"	"DYRK1A involvement regarding cell proliferation in brain development"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5T280"	"Putative methyltransferase C9orf114 OS=Homo sapiens OX=9606 GN=SPOUT1 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"376"	"42.0"	"7.43"	"496.36"	"4.18"	"1"	"1"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02598"	"51490"	"ENSG00000198917"	"SPOUT1"	"hsa:51490; Q0D2P6; Q5T280; Q6P469; Q6PGP9; Q6PIJ1; Q6PJV9"	""	""	"0"	"0"	"64.0"	"44.8"	"62.7"	"59.0"	"64.0"	"57.5"	"75.5"	"87.4"	"91.6"	"128.2"	"157.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NRY2"	"SOSS complex subunit C OS=Homo sapiens OX=9606 GN=INIP PE=1 SV=1"	"0.000"	""	"15"	"1"	"2"	"1"	"104"	"11.4"	"9.25"	"334.89"	"4.18"	"1"	"1"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	""	"Pf15925"	"58493"	"ENSG00000148153"	"INIP"	"hsa:58493; Q5VWJ7; Q96E04; Q9NRY2; Q9P090"	""	""	"0"	"0"	"41.5"	"31.8"	"38.5"	"50.3"	"56.3"	"42.9"	"53.5"	"86.6"	"64.5"	"161.9"	"162.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62875"	"DNA-directed RNA polymerases I, II, and III subunit RPABC5 OS=Homo sapiens OX=9606 GN=POLR2L PE=1 SV=1"	"0.000"	""	"16"	"1"	"2"	"1"	"67"	"7.6"	"7.77"	"466.77"	"4.16"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01194"	"5441"	"ENSG00000177700"	"POLR2L"	"hsa:5441; P52436; P62875; Q6FHX3"	"Pyrimidine metabolism; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"Activation of anterior HOX genes in hindbrain development during early embryogenesis; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; mRNA Splicing - Major Pathway; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; B-WICH complex positively regulates rRNA expression; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; Estrogen-dependent gene expression; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"56"	"0"	"73.7"	"60.1"	"97.8"	"80.7"	"80.0"	"71.2"	"124.7"	"255.6"	"256.4"	"647.4"	"987.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P2W1"	"Homologous-pairing protein 2 homolog OS=Homo sapiens OX=9606 GN=PSMC3IP PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"217"	"24.9"	"7.81"	"478.96"	"4.15"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf07106, Pf18517"	"29893"	"ENSG00000131470"	"PSMC3IP"	"C5ILB7; hsa:29893; Q14458; Q8WXG2; Q96HA2; Q9P2W1"	"Androgen receptor signaling pathway; Primary ovarian insufficiency"	"Meiotic recombination"	"3"	"0"	"63.6"	"48.2"	"62.8"	"54.5"	"52.1"	"54.0"	"67.1"	"98.6"	"92.7"	"149.9"	"216.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P17858"	"ATP-dependent 6-phosphofructokinase, liver type OS=Homo sapiens OX=9606 GN=PFKL PE=1 SV=6"	"0.000"	""	"1"	"1"	"2"	"1"	"780"	"85.0"	"7.50"	"377.62"	"4.15"	"1"	"1"	"other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00365"	"5211"	"ENSG00000141959"	"PFKL"	"hsa:5211; P17858; Q96A64; Q96IH4; Q9BR91"	"Photodynamic therapy-induced HIF-1 survival signaling; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Insulin signaling; Disorders of fructose metabolism; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"Neutrophil degranulation; Glycolysis"	"9"	"0"	"54.5"	"36.8"	"46.9"	"40.1"	"39.3"	"48.3"	"59.7"	"90.2"	"88.1"	"161.2"	"181.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P53999"	"Activated RNA polymerase II transcriptional coactivator p15 OS=Homo sapiens OX=9606 GN=SUB1 PE=1 SV=3"	"0.000"	""	"10"	"1"	"2"	"1"	"127"	"14.4"	"9.60"	"372.78"	"4.14"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02229"	"10923"	"ENSG00000113387"	"SUB1"	"hsa:10923; P53999; Q96L29"	""	""	"0"	"0"	"89.2"	"76.6"	"81.1"	"85.5"	"79.0"	"89.0"	"110.1"	"174.8"	"150.9"	"352.8"	"715.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14907"	"Tax1-binding protein 3 OS=Homo sapiens OX=9606 GN=TAX1BP3 PE=1 SV=2"	"0.000"	""	"14"	"1"	"2"	"1"	"124"	"13.7"	"8.48"	"470.02"	"4.14"	"1"	"1"	"cell-cell signaling;protein metabolism;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00595, Pf02163"	"30851"	"ENSG00000213977"	"TAX1BP3"	"B2RD53; D3DTJ6; hsa:30851; O14907; Q7LCQ4"	""	"RHO GTPases Activate Rhotekin and Rhophilins"	"1"	"0"	"28.3"	"25.0"	"33.8"	"27.0"	"32.9"	"36.2"	"41.4"	"110.6"	"116.5"	"356.3"	"453.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15392"	"Baculoviral IAP repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=BIRC5 PE=1 SV=3"	"0.000"	""	"8"	"1"	"2"	"1"	"142"	"16.4"	"5.90"	"398.27"	"4.13"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00653"	"332"	"ENSG00000089685"	"BIRC5"	"A2SUH6; B2R4R1; hsa:332; O15392; Q2I3N8; Q4VGX0; Q53F61; Q5MGC6; Q6FHL2; Q75SP2; Q9P2W8"	"Apoptosis modulation and signaling; Interleukin-11 signaling pathway; Apoptosis; Apoptosis-related network due to altered Notch3 in ovarian cancer; RAC1/PAK1/p38/MMP2 pathway; Photodynamic therapy-induced HIF-1 survival signaling; Photodynamic therapy-induced NF-kB survival signaling; Hepatitis C and hepatocellular carcinoma; VEGFA-VEGFR2 signaling; IL-4 signaling pathway; Chromosomal and microsatellite instability in colorectal cancer ; Extracellular vesicles in the crosstalk of cardiac cells; Gastrin signaling pathway; Hepatitis B infection"	"Separation of Sister Chromatids; Neddylation; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; SUMOylation of DNA replication proteins; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Interleukin-4 and Interleukin-13 signaling; TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"	"24"	"0"	"75.8"	"51.7"	"82.9"	"73.0"	"74.0"	"69.5"	"109.5"	"178.8"	"155.6"	"298.2"	"353.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16594"	"Transcription initiation factor TFIID subunit 9 OS=Homo sapiens OX=9606 GN=TAF9 PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"264"	"29.0"	"8.66"	"495.66"	"4.13"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02291"	"6880"	"ENSG00000273841; ENSG00000276463"	"TAF9"	"D3DWA3; hsa:6880; Q16594; Q5U0D1; Q9BTS1"	"Eukaryotic transcription initiation"	"HATs acetylate histones; RNA Polymerase II Pre-transcription Events; RNA polymerase II transcribes snRNA genes; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Regulation of TP53 Activity through Phosphorylation"	"12"	"0"	"27.8"	"19.3"	"26.8"	"30.3"	"21.3"	"20.6"	"30.5"	"50.4"	"46.3"	"117.9"	"156.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N5A5"	"Zinc finger CCCH-type with G patch domain-containing protein OS=Homo sapiens OX=9606 GN=ZGPAT PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"531"	"57.3"	"5.43"	"525.68"	"4.13"	"1"	"1"	"other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01585, Pf18044"	"84619"	"ENSG00000197114"	"ZGPAT"	"E1P5K1; hsa:84619; Q4VXN9; Q5JWI9; Q5JWJ0; Q8N5A5; Q8NC55; Q8WUV4; Q96JI0; Q96JU4; Q9H401"	""	""	"0"	"0"	"72.6"	"44.6"	"68.7"	"69.3"	"55.9"	"47.5"	"89.6"	"112.3"	"124.7"	"200.1"	"236.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NXW9"	"Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 OS=Homo sapiens OX=9606 GN=ALKBH4 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"302"	"33.8"	"6.67"	"435.57"	"4.13"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"cytoskeletal activity;other molecular function"	""	"54784"	"ENSG00000160993"	"ALKBH4"	"hsa:54784; Q53H92; Q9H6A4; Q9NXW9"	""	""	"0"	"0"	"68.2"	"57.5"	"63.6"	"61.1"	"53.9"	"75.5"	"130.3"	"311.0"	"350.3"	"541.8"	"483.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16643"	"Drebrin OS=Homo sapiens OX=9606 GN=DBN1 PE=1 SV=4"	"0.000"	""	"2"	"1"	"2"	"1"	"649"	"71.4"	"4.45"	"447.89"	"4.12"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00241"	"1627"	"ENSG00000113758"	"DBN1"	"A8MV58; B2RBG0; hsa:1627; Q16643; Q9UFZ5"	"5q35 copy number variation"	"RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle; RHOH GTPase cycle; RHOD GTPase cycle"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61586"	"Transforming protein RhoA OS=Homo sapiens OX=9606 GN=RHOA PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"193"	"21.8"	"6.10"	"405.09"	"4.11"	"1"	"1"	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00071"	"387"	"ENSG00000067560"	"RHOA"	"hsa:387; P06749; P61586; Q53HM4; Q5U024; Q9UDJ0; Q9UEJ4"	"Androgen receptor signaling pathway; Physiological and pathological hypertrophy of the heart; MicroRNAs in cardiomyocyte hypertrophy; Leptin signaling pathway; Pathogenic Escherichia coli infection; AGE/RAGE pathway; Corticotropin-releasing hormone signaling pathway; Spinal cord injury; Alpha 6 beta 4 signaling pathway; Focal adhesion; G protein signaling pathways; Wnt signaling pathway; Hypothetical craniofacial development pathway; Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; Wnt signaling pathway and pluripotency; Fibrin complement receptor 3 signaling pathway; Wnt signaling in kidney disease; Chromosomal and microsatellite instability in colorectal cancer ; Ebola virus infection in host; Ras signaling; Pancreatic adenocarcinoma pathway; Wnt signaling; Envelope proteins and their potential roles in EDMD physiopathology; Hippo signaling regulation pathways; Leukocyte-intrinsic Hippo pathway functions; Neural crest cell migration during development; Neural crest cell migration in cancer; Joubert syndrome; Gastrin signaling pathway; Netrin-UNC5B signaling pathway; mBDNF and proBDNF regulation of GABA neurotransmission; MAP3K1 role in promoting and blocking gonadal determination; Airway smooth muscle cell contraction; RAS and bradykinin pathways in COVID-19; Regulation of actin cytoskeleton; GDNF signaling; PtdIns(4,5)P2 in cytokinesis pathway; 2q11.2 copy number variation syndrome; 2q21.1 copy number variation syndrome; G13 signaling pathway; 13q12.12 copy number variation; DNA damage response (only ATM dependent); Serotonin HTR1 group and FOS pathway"	"VEGFA-VEGFR2 Pathway; RHOC GTPase cycle; RHOA GTPase cycle; G alpha (12/13) signalling events; RHO GTPases Activate Formins; Neutrophil degranulation; EPHB-mediated forward signaling; GPVI-mediated activation cascade; PI3K/AKT activation; ERBB2 Regulates Cell Motility; RHO GTPases activate CIT; G beta:gamma signalling through PI3Kgamma; PCP/CE pathway; RHO GTPases Activate Rhotekin and Rhophilins; EPHA-mediated growth cone collapse; Sema4D induced cell migration and growth-cone collapse; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; Sema4D mediated inhibition of cell attachment and migration; Ovarian tumor domain proteases; SLIT2:ROBO1 increases RHOA activity; PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases; TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition); Axonal growth stimulation; Axonal growth inhibition (RHOA activation); RHO GTPases activate KTN1"	"70"	"0"	"26.3"	"18.8"	"30.2"	"28.3"	"21.8"	"24.0"	"28.6"	"42.9"	"43.2"	"74.1"	"94.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51398"	"28S ribosomal protein S29, mitochondrial OS=Homo sapiens OX=9606 GN=DAP3 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"398"	"45.5"	"8.88"	"464.02"	"4.11"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf10236"	"7818"	"ENSG00000132676"	"DAP3"	"B4DP59; B4DY62; E7EM60; hsa:7818; P51398; Q13044; Q68CT7; Q96Q20"	"CKAP4 signaling pathway map"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"4"	"0"	"31.4"	"24.7"	"32.8"	"41.2"	"33.5"	"32.2"	"36.3"	"64.6"	"54.9"	"128.6"	"187.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46778"	"60S ribosomal protein L21 OS=Homo sapiens OX=9606 GN=RPL21 PE=1 SV=2"	"0.000"	""	"16"	"2"	"3"	"2"	"160"	"18.6"	"10.49"	"697.13"	"4.11"	"2"	"1"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;other cell component"	"other molecular function"	"Pf01157"	"6144"	"ENSG00000122026"	"RPL21"	"hsa:6144; P46778; Q16699"	"Cytoplasmic ribosomal proteins"	"SRP-dependent cotranslational protein targeting to membrane; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"140.6"	"121.1"	"180.3"	"158.9"	"160.8"	"187.1"	"218.9"	"321.0"	"361.4"	"750.5"	"1219.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q13685"	"Angio-associated migratory cell protein OS=Homo sapiens OX=9606 GN=AAMP PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"434"	"46.7"	"4.42"	""	"4.10"	""	"1"	"developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00400"	"14"	"ENSG00000127837"	"AAMP"	"hsa:14; Q13685; Q8WUJ9; Q96H92"	"Nucleotide-binding oligomerization domain (NOD) pathway"	"NOD1/2 Signaling Pathway; Thromboxane signalling through TP receptor; Signaling by EGFR; Signaling by VEGF"	"5"	"0"	"20.5"	"11.6"	"20.2"	"18.1"	"21.2"	"21.1"	"22.3"	"38.6"	"41.2"	"74.0"	"135.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4B6"	"DDB1- and CUL4-associated factor 1 OS=Homo sapiens OX=9606 GN=DCAF1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1507"	"168.9"	"5.06"	"354.50"	"4.10"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	""	"9730"	"ENSG00000145041"	"DCAF1"	"hsa:9730; Q2YD74; Q8TBD9; Q9HCA1; Q9UG37; Q9Y4B6"	"Hippo-Merlin signaling dysregulation"	"Antigen processing: Ubiquitination & Proteasome degradation"	"2"	"0"	"33.8"	"27.2"	"23.7"	"37.4"	"29.5"	"33.8"	"41.4"	"73.1"	"64.7"	"151.2"	"218.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H939"	"Proline-serine-threonine phosphatase-interacting protein 2 OS=Homo sapiens OX=9606 GN=PSTPIP2 PE=1 SV=4"	"0.000"	""	"4"	"1"	"2"	"1"	"334"	"38.8"	"8.48"	"260.85"	"4.09"	"1"	"1"	"cell organization and biogenesis"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf00611"	"9050"	"ENSG00000152229"	"PSTPIP2"	"hsa:9050; Q9H939"	""	""	"0"	"0"	"43.7"	"25.0"	"45.8"	"46.5"	"44.3"	"39.5"	"55.7"	"72.8"	"69.1"	"100.7"	"116.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q4V328"	"GRIP1-associated protein 1 OS=Homo sapiens OX=9606 GN=GRIPAP1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"841"	"95.9"	"5.11"	"378.98"	"4.09"	"1"	"1"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	""	"56850"	"ENSG00000068400"	"GRIPAP1"	"A6NL78; hsa:56850; Q3MJ75; Q4V327; Q4V328; Q4V330; Q5HYG1; Q6N046; Q96DH8; Q9NQ43; Q9ULQ3"	""	""	"0"	"0"	"17.9"	"14.2"	"24.9"	"22.5"	"15.4"	"15.2"	"25.1"	"78.1"	"84.9"	"207.0"	"262.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NUQ8"	"ATP-binding cassette sub-family F member 3 OS=Homo sapiens OX=9606 GN=ABCF3 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"709"	"79.7"	"6.34"	"406.22"	"4.08"	"1"	"1"	"stress response"	""	"other molecular function"	"Pf00005, Pf12848"	"55324"	"ENSG00000161204"	"ABCF3"	"A8K241; hsa:55324; Q86UA2; Q8NAN1; Q96GS8; Q9H7A8; Q9NUQ8"	""	""	"0"	"0"	"35.0"	"28.8"	"40.5"	"37.9"	"32.0"	"28.1"	"43.2"	"92.1"	"80.2"	"137.5"	"151.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UIA9"	"Exportin-7 OS=Homo sapiens OX=9606 GN=XPO7 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"1087"	"123.8"	"6.32"	"481.22"	"4.08"	"1"	"1"	"transport"	"nucleus;other cell component"	"other molecular function"	"Pf03810"	"23039"	"ENSG00000130227"	"XPO7"	"hsa:23039; O94846; Q6PJK9; Q8NEK7; Q9UIA9"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75153"	"Clustered mitochondria protein homolog OS=Homo sapiens OX=9606 GN=CLUH PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"1309"	"146.6"	"6.13"	"418.63"	"4.07"	"1"	"1"	"cell organization and biogenesis"	"other cell component"	"nucleic acid binding activity"	"Pf12807, Pf13236, Pf13374, Pf13424, Pf15044"	"23277"	"ENSG00000132361"	"CLUH"	"hsa:23277; O75153; Q6AHY2; Q6P3X7; Q6ZUG8; Q8N4U7; Q9BTA3; Q9H979"	"Translation factors"	""	"1"	"0"	"4.3"	"0.0"	"4.7"	"6.1"	"5.2"	"3.8"	"6.1"	"17.1"	"19.5"	"42.6"	"54.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5X3"	"Sorting nexin-5 OS=Homo sapiens OX=9606 GN=SNX5 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"404"	"46.8"	"6.76"	"314.59"	"4.07"	"1"	"1"	"protein metabolism;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00787, Pf09325"	"27131"	"ENSG00000089006"	"SNX5"	"B7ZKN3; D3DW26; hsa:27131; Q52LC4; Q7KZN0; Q9BWP0; Q9Y5X3"	""	"Golgi Associated Vesicle Biogenesis"	"1"	"0"	"16.0"	"7.0"	"25.1"	"19.9"	"18.0"	"16.6"	"23.2"	"74.0"	"59.1"	"252.1"	"312.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P82664"	"28S ribosomal protein S10, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS10 PE=1 SV=2"	"0.000"	""	"7"	"1"	"2"	"1"	"201"	"23.0"	"8.00"	"449.37"	"4.06"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	""	"Pf00338"	"55173"	"ENSG00000048544"	"MRPS10"	"B2RE89; hsa:55173; P82664; Q9H3E5; Q9NVR3"	""	"Mitochondrial translation elongation; Mitochondrial translation initiation; Mitochondrial translation termination"	"3"	"0"	"14.1"	"7.0"	"11.9"	"12.0"	"7.8"	"14.1"	"17.6"	"48.7"	"42.5"	"131.7"	"200.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5T447"	"E3 ubiquitin-protein ligase HECTD3 OS=Homo sapiens OX=9606 GN=HECTD3 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"861"	"97.1"	"5.64"	"657.08"	"4.06"	"1"	"1"	"protein metabolism;other metabolic processes"	"other cell component"	"other molecular function"	"Pf00632, Pf03256"	"79654"	"ENSG00000126107"	"HECTD3"	"B3KPV7; B3KRH4; hsa:79654; Q5T447; Q5T448; Q9H783"	""	"Antigen processing: Ubiquitination & Proteasome degradation"	"1"	"0"	"5.1"	"3.6"	"5.3"	"3.6"	"2.7"	"1.8"	"8.2"	"17.1"	"16.2"	"38.5"	"62.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q02978"	"Mitochondrial 2-oxoglutarate/malate carrier protein OS=Homo sapiens OX=9606 GN=SLC25A11 PE=1 SV=3"	"0.000"	""	"4"	"1"	"2"	"1"	"314"	"34.0"	"9.91"	"503.43"	"4.05"	"1"	"1"	"other metabolic processes;transport"	"plasma membrane;other membranes;mitochondrion"	"transporter activity"	"Pf00153"	"8402"	"ENSG00000108528"	"SLC25A11"	"F5GY65; hsa:8402; O75537; Q02978; Q969P7"	"VEGFA-VEGFR2 signaling"	"Gluconeogenesis"	"2"	"0"	"8.0"	"2.4"	"4.5"	"6.3"	"4.9"	"7.0"	"7.6"	"15.5"	"21.6"	"57.2"	"83.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61244"	"Protein max OS=Homo sapiens OX=9606 GN=MAX PE=1 SV=1"	"0.000"	""	"11"	"2"	"3"	"2"	"160"	"18.3"	"6.30"	"721.70"	"4.05"	"2"	"1"	"cell organization and biogenesis;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00010"	"4149"	"ENSG00000125952"	"MAX"	"A6NH73; A8K265; A8K4G4; A8K824; hsa:4149; P25912; P52163; P61244; Q14803; Q96CY8"	"B cell receptor signaling pathway; Pathways affected in adenoid cystic carcinoma; MAPK signaling pathway; p38 MAPK signaling pathway; Small cell lung cancer; Pleural mesothelioma; 5q35 copy number variation"	"Transcriptional Regulation by E2F6; Cyclin E associated events during G1/S transition ; Transcription of E2F targets under negative control by DREAM complex; Cyclin A:Cdk2-associated events at S phase entry"	"11"	"0"	"319.5"	"262.4"	"291.9"	"288.0"	"255.2"	"241.8"	"331.6"	"519.7"	"508.2"	"1328.9"	"1804.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P47914"	"60S ribosomal protein L29 OS=Homo sapiens OX=9606 GN=RPL29 PE=1 SV=2"	"0.000"	""	"9"	"1"	"2"	"1"	"159"	"17.7"	"11.66"	"420.76"	"4.05"	"1"	"1"	"protein metabolism;other metabolic processes;developmental processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01779"	"6159"	"ENSG00000162244"	"RPL29"	"A8K0H3; B2R4M8; hsa:6159; P47914; Q6IPY3"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"52.1"	"59.1"	"59.4"	"53.3"	"58.4"	"62.0"	"73.4"	"93.2"	"112.4"	"178.6"	"266.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UPN4"	"Centrosomal protein of 131 kDa OS=Homo sapiens OX=9606 GN=CEP131 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1083"	"122.1"	"8.69"	"393.05"	"4.04"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	""	"22994"	"ENSG00000141577"	"CEP131"	"A6NHI8; B2RN11; hsa:22994; Q96F50; Q9UPN4"	""	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"7"	"0"	"23.0"	"16.5"	"27.1"	"29.8"	"28.8"	"25.0"	"34.8"	"54.9"	"60.2"	"119.0"	"161.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9H9H4"	"Vacuolar protein sorting-associated protein 37B OS=Homo sapiens OX=9606 GN=VPS37B PE=1 SV=1"	""	""	"9"	"1"	"1"	"1"	"285"	"31.3"	"7.34"	""	"4.04"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf07200"	"79720"	"ENSG00000139722"	"VPS37B"	"hsa:79720; Q9H9H4"	"7q11.23 copy number variation syndrome"	"HCMV Late Events; Budding and maturation of HIV virion; Membrane binding and targetting of GAG proteins; Endosomal Sorting Complex Required For Transport (ESCRT); Late endosomal microautophagy"	"6"	"0"	"5.8"	"0.0"	"3.2"	"6.2"	"6.9"	"6.0"	"9.0"	"16.4"	"13.5"	"31.4"	"31.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BRR8"	"G patch domain-containing protein 1 OS=Homo sapiens OX=9606 GN=GPATCH1 PE=1 SV=1"	"0.000"	""	"4"	"2"	"2"	"2"	"931"	"103.3"	"7.05"	"488.64"	"4.04"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf01585, Pf07713"	"55094"	"ENSG00000076650"	"GPATCH1"	"hsa:55094; Q8IZV6; Q8N3B7; Q9BRR8; Q9NW94"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"31.8"	"17.5"	"33.6"	"27.4"	"32.2"	"28.7"	"53.2"	"70.1"	"89.9"	"184.4"	"295.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9GZR7"	"ATP-dependent RNA helicase DDX24 OS=Homo sapiens OX=9606 GN=DDX24 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"859"	"96.3"	"9.06"	"458.11"	"4.04"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00270, Pf00271"	"57062"	"ENSG00000089737; ENSG00000273761"	"DDX24"	"E7EMJ4; hsa:57062; Q4V9L5; Q9GZR7"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43663"	"Protein regulator of cytokinesis 1 OS=Homo sapiens OX=9606 GN=PRC1 PE=1 SV=2"	"0.000"	""	"7"	"4"	"6"	"3"	"620"	"71.6"	"6.68"	"2179.93"	"4.03"	"4"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03999"	"9055"	"ENSG00000198901"	"PRC1"	"A6NC44; B4DLR1; H9KV59; hsa:9055; O43663; Q9BSB6"	""	"RHO GTPases activate CIT"	"1"	"0"	"212.7"	"195.6"	"179.3"	"192.3"	"184.4"	"202.6"	"249.5"	"467.5"	"454.2"	"730.3"	"866.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96L93"	"Kinesin-like protein KIF16B OS=Homo sapiens OX=9606 GN=KIF16B PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1317"	"151.9"	"6.16"	"420.83"	"4.03"	"1"	"1"	"other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225, Pf00498, Pf00787"	"55614"	"ENSG00000089177"	"KIF16B"	"A6NKJ9; A7E2A8; B1AKG3; B1AKT7; C9JDN5; C9JI52; C9JSM8; C9JWJ7; hsa:55614; Q2TBF5; Q5HYC0; Q5HYK1; Q5JWW3; Q5TFK5; Q86VL9; Q86YS5; Q8IYU0; Q96L93; Q9BQJ8; Q9BQM0; Q9BQM1; Q9BQM5; Q9H5U0; Q9HCI2; Q9NXN9"	""	"COPI-dependent Golgi-to-ER retrograde traffic; Kinesins"	"2"	"0"	"35.4"	"22.1"	"40.8"	"35.3"	"29.6"	"40.0"	"46.6"	"110.3"	"101.9"	"125.7"	"141.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BXK1"	"Krueppel-like factor 16 OS=Homo sapiens OX=9606 GN=KLF16 PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"252"	"25.4"	"9.88"	"491.18"	"4.02"	"1"	"1"	"signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00096"	"83855"	"ENSG00000129911"	"KLF16"	"hsa:83855; Q9BXK1"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96L91"	"E1A-binding protein p400 OS=Homo sapiens OX=9606 GN=EP400 PE=1 SV=4"	"0.000"	""	"0"	"1"	"2"	"1"	"3159"	"343.3"	"9.19"	"456.37"	"4.02"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf07529, Pf15790"	"57634"	"ENSG00000183495"	"EP400"	"hsa:57634; O15411; Q6P2F5; Q8N8Q7; Q8NE05; Q96JK7; Q96L91; Q9P230"	""	"Formation of Senescence-Associated Heterochromatin Foci (SAHF); HATs acetylate histones"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15005"	"Signal peptidase complex subunit 2 OS=Homo sapiens OX=9606 GN=SPCS2 PE=1 SV=3"	"0.000"	""	"8"	"1"	"2"	"1"	"226"	"25.0"	"8.47"	"551.42"	"4.02"	"1"	"1"	"protein metabolism;other metabolic processes;transport"	"other membranes;ER/Golgi"	""	"Pf06703"	"9789"	"ENSG00000118363"	"SPCS2"	"hsa:9789; Q15005; Q15507; Q3KQT0; Q641R4; Q6FG65; Q6IRX0; Q6P1P4; Q96HU9"	"15q25 copy number variation"	"SRP-dependent cotranslational protein targeting to membrane; Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1); Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP); Synthesis, secretion, and deacylation of Ghrelin"	"5"	"0"	"3.4"	"4.2"	"4.6"	"6.0"	"8.3"	"5.4"	"8.7"	"21.0"	"20.8"	"52.3"	"75.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6IA86"	"Elongator complex protein 2 OS=Homo sapiens OX=9606 GN=ELP2 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"826"	"92.4"	"5.96"	"303.92"	"4.01"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00400"	"55250"	"ENSG00000134759"	"ELP2"	"A8KAI6; B4DTG0; B4DXP0; E7EP23; E9PCX0; hsa:55250; Q53GZ0; Q687Y8; Q6IA86; Q8N5C2; Q96GV4; Q96PI7; Q9H9N0; Q9NV81"	""	"HATs acetylate histones"	"1"	"0"	"10.6"	"6.5"	"13.9"	"10.4"	"7.5"	"9.5"	"14.6"	"26.7"	"22.4"	"181.8"	"453.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BYG3"	"MKI67 FHA domain-interacting nucleolar phosphoprotein OS=Homo sapiens OX=9606 GN=NIFK PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"293"	"34.2"	"9.88"	"416.30"	"4.01"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf12196"	"84365"	"ENSG00000155438"	"NIFK"	"A8K788; hsa:84365; Q8TB66; Q96ED4; Q9BYG3"	""	""	"0"	"0"	"35.6"	"24.5"	"33.0"	"31.7"	"41.6"	"32.3"	"48.7"	"74.1"	"62.2"	"137.4"	"237.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BV81"	"ER membrane protein complex subunit 6 OS=Homo sapiens OX=9606 GN=EMC6 PE=1 SV=1"	"0.000"	""	"12"	"1"	"2"	"1"	"110"	"12.0"	"10.07"	"504.16"	"4.01"	"1"	"1"	"cell organization and biogenesis;other metabolic processes"	"other membranes;ER/Golgi"	""	"Pf07019"	"83460"	"ENSG00000127774"	"EMC6"	"hsa:83460; Q9BV81"	""	""	"0"	"0"	"5.5"	"6.3"	"5.7"	"6.9"	"5.1"	"7.4"	"7.3"	"17.9"	"15.9"	"33.0"	"38.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NQA3"	"WAS protein family homolog 6 OS=Homo sapiens OX=9606 GN=WASH6P PE=1 SV=3"	"0.000"	""	"4"	"1"	"2"	"1"	"447"	"48.0"	"5.67"	"385.91"	"4.00"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"cytoskeletal activity"	"Pf11945"	""	""	"WASH6P"	"A6NGF1; Q8N305; Q9NQA3"	""	""	"0"	"0"	"16.0"	"9.1"	"22.8"	"14.3"	"17.0"	"17.2"	"14.0"	"32.2"	"25.6"	"39.5"	"58.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A8MT69"	"Centromere protein X OS=Homo sapiens OX=9606 GN=CENPX PE=1 SV=1"	"0.000"	""	"17"	"1"	"2"	"1"	"81"	"9.0"	"5.90"	"400.62"	"3.98"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf09415"	"201254"	"ENSG00000169689"	"CENPX"	"A8MT69; hsa:201254; O00281; O00282; Q96DD4; Q96F51"	"DNA repair pathways, full network"	"Fanconi Anemia Pathway; Deposition of new CENPA-containing nucleosomes at the centromere"	"3"	"0"	"3.5"	"3.1"	"4.1"	"0.0"	"0.0"	"0.0"	"2.8"	"16.6"	"21.8"	"96.3"	"175.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NRW3"	"DNA dC->dU-editing enzyme APOBEC-3C OS=Homo sapiens OX=9606 GN=APOBEC3C PE=1 SV=2"	"0.001"	""	"12"	"2"	"2"	"2"	"190"	"22.8"	"7.59"	"232.10"	"3.98"	"1"	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf18782"	"27350"	"ENSG00000244509"	"APOBEC3C"	"B2R884; hsa:27350; Q5JZ92; Q7Z2N7; Q96F12; Q9NRW3"	""	"Formation of the Editosome"	"2"	"0"	"83.9"	"42.2"	"72.0"	"73.6"	"58.0"	"67.0"	"101.0"	"156.4"	"148.9"	"442.6"	"609.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42025"	"Beta-centractin OS=Homo sapiens OX=9606 GN=ACTR1B PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"376"	"42.3"	"6.40"	"401.84"	"3.97"	"1"	"1"	""	"non-structural extracellular;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00022"	"10120"	"ENSG00000115073"	"ACTR1B"	"D3DVH2; hsa:10120; P42025; Q53SK5; Q9BRB7"	""	"Neutrophil degranulation; MHC class II antigen presentation"	"2"	"0"	"57.4"	"41.5"	"75.8"	"53.2"	"59.2"	"57.6"	"71.8"	"138.4"	"159.1"	"434.2"	"528.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NYB0"	"Telomeric repeat-binding factor 2-interacting protein 1 OS=Homo sapiens OX=9606 GN=TERF2IP PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"399"	"44.2"	"4.73"	"460.76"	"3.96"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf08914, Pf11626, Pf16589"	"54386"	"ENSG00000166848"	"TERF2IP"	"B4DQN4; hsa:54386; Q4W4Y2; Q8WYZ3; Q9NWR2; Q9NYB0"	"Splicing factor NOVA regulated synaptic proteins; SARS-CoV-2 mitochondrial chronic oxidative stress and endothelial dysfunction"	"DNA Damage/Telomere Stress Induced Senescence; Meiotic synapsis; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; Packaging Of Telomere Ends; Polymerase switching on the C-strand of the telomere; Telomere Extension By Telomerase; Telomere C-strand synthesis initiation; Removal of the Flap Intermediate from the C-strand"	"16"	"0"	"17.4"	"16.3"	"21.4"	"11.1"	"12.4"	"11.2"	"23.8"	"38.7"	"33.4"	"64.3"	"84.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O14734"	"Acyl-coenzyme A thioesterase 8 OS=Homo sapiens OX=9606 GN=ACOT8 PE=1 SV=1"	""	""	"7"	"1"	"1"	"1"	"319"	"35.9"	"7.56"	""	"3.96"	""	"1"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"cytosol;other cytoplasmic organelle"	"other molecular function"	"Pf13622"	"10005"	"ENSG00000101473"	"ACOT8"	"hsa:10005; O14734; O15261; Q17RX4"	""	"Peroxisomal protein import; Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol; alpha-linolenic acid (ALA) metabolism; Beta-oxidation of pristanoyl-CoA; Beta-oxidation of very long chain fatty acids"	"5"	"0"	"27.1"	"10.7"	"23.7"	"28.1"	"23.5"	"18.9"	"26.7"	"51.5"	"50.6"	"92.6"	"124.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96ME7"	"Zinc finger protein 512 OS=Homo sapiens OX=9606 GN=ZNF512 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"567"	"64.6"	"9.76"	"573.57"	"3.95"	"1"	"1"	""	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00096"	"84450"	"ENSG00000243943"	"ZNF512"	"B4DSM5; hsa:84450; Q53RZ7; Q86XK6; Q96JM0; Q96ME7"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86X10"	"Ral GTPase-activating protein subunit beta OS=Homo sapiens OX=9606 GN=RALGAPB PE=1 SV=1"	"0.000"	""	"2"	"2"	"3"	"2"	"1494"	"166.7"	"6.79"	"703.49"	"3.95"	"2"	"1"	"other biological processes"	""	"enzyme regulator activity;other molecular function"	"Pf20412"	"57148"	"ENSG00000170471"	"RALGAPB"	"A2A2E8; A2A2E9; hsa:57148; Q5TG31; Q86X10; Q8N3D1; Q8WWC0; Q9H3X8; Q9UJR1; Q9ULK1; Q9Y3G9"	""	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"	"1"	"0"	"41.4"	"33.5"	"51.2"	"48.9"	"44.9"	"57.5"	"71.2"	"218.0"	"223.7"	"406.4"	"500.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NT62"	"Ubiquitin-like-conjugating enzyme ATG3 OS=Homo sapiens OX=9606 GN=ATG3 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"314"	"35.8"	"4.74"	"369.83"	"3.94"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf03987"	"64422"	"ENSG00000144848"	"ATG3"	"hsa:64422; Q6PKC5; Q9H6L9; Q9NT62"	"Nanoparticle triggered autophagic cell death; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Autophagy; Clock-controlled autophagy in bone metabolism"	"Macroautophagy"	"5"	"0"	"44.4"	"38.9"	"34.8"	"33.9"	"37.2"	"35.5"	"42.8"	"69.9"	"63.5"	"108.9"	"138.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z4I7"	"LIM and senescent cell antigen-like-containing domain protein 2 OS=Homo sapiens OX=9606 GN=LIMS2 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"341"	"38.9"	"8.05"	"472.42"	"3.94"	"1"	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00412"	"55679"	"ENSG00000072163"	"LIMS2"	"A6NLH0; B4DMV1; F5H6E6; hsa:55679; Q7Z4I2; Q7Z4I6; Q7Z4I7; Q7Z4I8; Q8NFE7; Q9HA13"	""	"Cell-extracellular matrix interactions"	"1"	"0"	"80.0"	"59.3"	"83.5"	"69.2"	"77.1"	"59.1"	"95.5"	"456.4"	"449.7"	"942.8"	"962.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H3U1"	"Protein unc-45 homolog A OS=Homo sapiens OX=9606 GN=UNC45A PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"944"	"103.0"	"6.07"	"400.39"	"3.93"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf11701, Pf13181, Pf13432"	"55898"	"ENSG00000140553"	"UNC45A"	"A8K6F7; hsa:55898; Q7L3Y6; Q9H3U1; Q9H3U8; Q9NSE8; Q9NSE9"	""	""	"0"	"0"	"11.9"	"9.0"	"9.3"	"9.8"	"8.8"	"10.3"	"15.6"	"52.3"	"45.5"	"162.2"	"250.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9GZS3"	"WD repeat-containing protein 61 OS=Homo sapiens OX=9606 GN=WDR61 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"305"	"33.6"	"5.47"	"346.87"	"3.93"	"1"	"1"	"cell-cell signaling;protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf00400"	"80349"	"ENSG00000140395"	"SKIC8"	"D3DW84; hsa:80349; Q6IA22; Q7Z4X4; Q9GZS3"	""	"E3 ubiquitin ligases ubiquitinate target proteins; Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events; mRNA decay by 3' to 5' exoribonuclease"	"5"	"0"	"23.8"	"18.3"	"25.8"	"20.7"	"20.3"	"18.7"	"27.4"	"66.7"	"54.5"	"200.2"	"375.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99700"	"Ataxin-2 OS=Homo sapiens OX=9606 GN=ATXN2 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1313"	"140.2"	"9.57"	"414.99"	"3.93"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity"	"Pf06741, Pf07145, Pf14438"	"6311"	"ENSG00000204842"	"ATXN2"	"A6NLD4; hsa:6311; Q24JQ7; Q6ZQZ7; Q99493; Q99700"	"Parkinson's disease pathway; EGF/EGFR signaling pathway"	""	"2"	"0"	"20.2"	"9.7"	"23.5"	"26.1"	"31.9"	"18.1"	"27.3"	"35.3"	"31.7"	"56.9"	"52.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q93096"	"Protein tyrosine phosphatase type IVA 1 OS=Homo sapiens OX=9606 GN=PTP4A1 PE=1 SV=2"	"0.000"	""	"7"	"1"	"3"	"1"	"173"	"19.8"	"8.97"	"793.78"	"3.92"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00782"	"7803"	"ENSG00000112245"	"PTP4A1"	"B2R6C8; hsa:7803; O00648; Q49A54; Q93096"	""	""	"0"	"0"	"26.6"	"16.3"	"25.0"	"15.5"	"31.9"	"25.0"	"38.5"	"62.9"	"81.9"	"119.5"	"137.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35226"	"Polycomb complex protein BMI-1 OS=Homo sapiens OX=9606 GN=BMI1 PE=1 SV=2"	"0.000"	""	"6"	"2"	"2"	"2"	"326"	"36.9"	"8.63"	"248.90"	"3.92"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf13923, Pf16207"	"100532731; 648"	"ENSG00000168283"	"BMI1"	"hsa:100532731; hsa:648; P35226; Q16030; Q5T8Z3; Q96F37"	"Pleural mesothelioma; Interactions of natural killer cells in pancreatic cancer; CCL18 signaling pathway"	"SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Oxidative Stress Induced Senescence; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6"	"12"	"0"	"99.3"	"66.3"	"124.9"	"108.3"	"78.7"	"86.3"	"116.2"	"382.9"	"397.5"	"886.1"	"1167.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13042"	"Cell division cycle protein 16 homolog OS=Homo sapiens OX=9606 GN=CDC16 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"620"	"71.6"	"5.85"	"447.08"	"3.92"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	""	"Pf12895, Pf13424"	"8881"	"ENSG00000130177"	"CDC16"	"A2A365; hsa:8881; Q13042; Q5T8C8; Q7Z651; Q96AE6; Q9Y564"	"Cell cycle"	"Assembly of the pre-replicative complex; Separation of Sister Chromatids; Antigen processing: Ubiquitination & Proteasome degradation; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; CDK-mediated phosphorylation and removal of Cdc6; Autodegradation of Cdh1 by Cdh1:APC/C; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of Cyclin B; Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase; Regulation of APC/C activators between G1/S and early anaphase; Phosphorylation of the APC/C; APC-Cdc20 mediated degradation of Nek2A; Senescence-Associated Secretory Phenotype (SASP); Transcriptional Regulation by VENTX; Aberrant regulation of mitotic exit in cancer due to RB1 defects"	"19"	"0"	"30.2"	"14.9"	"26.6"	"30.4"	"29.3"	"18.5"	"31.5"	"62.3"	"62.8"	"159.1"	"183.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UPY3"	"Endoribonuclease Dicer OS=Homo sapiens OX=9606 GN=DICER1 PE=1 SV=3"	""	""	"1"	"1"	"1"	"1"	"1922"	"218.5"	"5.68"	""	"3.92"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00271, Pf00636, Pf02170, Pf03368, Pf04851"	"23405"	"ENSG00000100697"	"DICER1"	"A7E2D3; B3KRG4; E0AD28; hsa:23405; O95943; Q9UPY3; Q9UQ02"	"miRNA biogenesis; exRNA mechanism of action and biogenesis; Hypoxia-mediated EMT and stemness; mRNA processing; Fragile X syndrome; Influence of laminopathies on Wnt signaling; Overlap between signal transduction pathways contributing to LMNA laminopathies"	"MicroRNA (miRNA) biogenesis; Small interfering RNA (siRNA) biogenesis; tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis"	"10"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14669"	"E3 ubiquitin-protein ligase TRIP12 OS=Homo sapiens OX=9606 GN=TRIP12 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1992"	"220.3"	"8.48"	"335.63"	"3.90"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00632"	"9320"	"ENSG00000153827"	"TRIP12"	"D4HL82; hsa:9320; Q14669; Q14CA3; Q14CF1; Q15644; Q53R87; Q53TE7"	""	"Antigen processing: Ubiquitination & Proteasome degradation"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96H20"	"Vacuolar-sorting protein SNF8 OS=Homo sapiens OX=9606 GN=SNF8 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"258"	"28.8"	"6.65"	"334.46"	"3.90"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf04157"	"11267"	"ENSG00000159210"	"SNF8"	"hsa:11267; Q8IXY3; Q96H20; Q9UN50"	""	"Endosomal Sorting Complex Required For Transport (ESCRT); HCMV Late Events"	"2"	"0"	"38.4"	"28.7"	"46.9"	"40.2"	"57.8"	"90.6"	"117.8"	"260.0"	"291.5"	"540.2"	"591.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BZX2"	"Uridine-cytidine kinase 2 OS=Homo sapiens OX=9606 GN=UCK2 PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"261"	"29.3"	"6.70"	"523.49"	"3.89"	"1"	"1"	"other metabolic processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00485"	"7371"	"ENSG00000143179"	"UCK2"	"hsa:7371; Q5VV91; Q7KZV3; Q92528; Q96KG5; Q9BU42; Q9BZX2"	"Fluoropyrimidine activity; Pyrimidine metabolism"	"Pyrimidine salvage"	"3"	"0"	"9.4"	"4.0"	"10.0"	"9.1"	"7.5"	"11.1"	"11.7"	"20.7"	"23.7"	"56.6"	"78.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14254"	"Flotillin-2 OS=Homo sapiens OX=9606 GN=FLOT2 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"428"	"47.0"	"5.25"	"495.15"	"3.88"	"1"	"1"	"cell adhesion;transport;other biological processes"	"plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	""	"Pf01145"	"2319"	"ENSG00000132589"	"FLOT2"	"hsa:2319; Q14254"	"Angiopoietin-like protein 8 regulatory pathway; Insulin signaling"	"RHOA GTPase cycle; RHOB GTPase cycle; Regulation of necroptotic cell death; RND1 GTPase cycle; RND3 GTPase cycle; RHOC GTPase cycle; Synaptic adhesion-like molecules"	"10"	"0"	"17.2"	"8.5"	"13.0"	"9.9"	"11.5"	"12.3"	"14.3"	"26.8"	"28.8"	"102.5"	"201.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19174"	"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 OS=Homo sapiens OX=9606 GN=PLCG1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1290"	"148.4"	"6.05"	"532.34"	"3.88"	"1"	"1"	"other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00017, Pf00018, Pf00168, Pf00387, Pf00388"	"5335"	"ENSG00000124181"	"PLCG1"	"B7ZLY7; B9EGH4; E1P5W4; hsa:5335; P19174; Q2V575"	"Angiogenesis; IL-1 signaling pathway; RANKL/RANK signaling pathway; Leptin signaling pathway; Glioblastoma signaling pathways; B cell receptor signaling pathway; Corticotropin-releasing hormone signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; PDGF pathway; Primary focal segmental glomerulosclerosis (FSGS); T cell receptor and co-stimulatory signaling; Myometrial relaxation and contraction pathways; Kit receptor signaling pathway; MFAP5-mediated ovarian cancer cell motility and invasiveness; BDNF-TrkB signaling; Physico-chemical features and toxicity-associated pathways; T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection; VEGFA-VEGFR2 signaling; GPR40 pathway; Ras signaling; Non-small cell lung cancer; EGF/EGFR signaling pathway; Resistin as a regulator of inflammation; Fragile X syndrome; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Gastrin signaling pathway; IL-18 signaling pathway; EGFR tyrosine kinase inhibitor resistance; mBDNF and proBDNF regulation of GABA neurotransmission; Modulators of TCR signaling and T cell activation; CCL18 signaling pathway; Th17 cell differentiation pathway; GDNF signaling; A network map of Macrophage-stimulating protein (MSP) signaling; 4p16.3 copy number variation; 5q35 copy number variation; ErbB signaling pathway; T-cell receptor signaling pathway"	"ISG15 antiviral mechanism; Role of phospholipids in phagocytosis; FCERI mediated MAPK activation; FCERI mediated Ca+2 mobilization; FCGR3A-mediated IL10 synthesis; Generation of second messenger molecules; Signaling by ALK fusions and activated point mutants; RET signaling; Downstream signal transduction; Signaling by ALK; DAP12 signaling; Signaling by ERBB2 KD Mutants; Signaling by ERBB2 TMD/JMD mutants; EGFR interacts with phospholipase C-gamma; Signaling by FGFR1 in disease; Synthesis of IP3 and IP4 in the cytosol; Phospholipase C-mediated cascade: FGFR1; Phospholipase C-mediated cascade; FGFR2; Signaling by FGFR2 in disease; VEGFR2 mediated cell proliferation; Phospholipase C-mediated cascade; FGFR3; Phospholipase C-mediated cascade; FGFR4; Signaling by FGFR3 in disease; DAG and IP3 signaling; Erythropoietin activates Phospholipase C gamma (PLCG); Role of second messengers in netrin-1 signaling; Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; PLCG1 events in ERBB2 signaling; Constitutive Signaling by EGFRvIII; Signaling by ERBB2 ECD mutants; Signaling by FGFR4 in disease; PLC-gamma1 signalling; PECAM1 interactions; Activated NTRK2 signals through PLCG1; Activated NTRK3 signals through PLCG1"	"73"	"0"	"3.3"	"7.1"	"5.0"	"5.3"	"5.3"	"6.9"	"10.5"	"41.3"	"25.7"	"127.3"	"167.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75718"	"Cartilage-associated protein OS=Homo sapiens OX=9606 GN=CRTAP PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"401"	"46.5"	"5.73"	"341.31"	"3.88"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;ER/Golgi;other cell component"	""	""	"10491"	"ENSG00000170275"	"CRTAP"	"B2RBL6; hsa:10491; O75718"	"Type I collagen synthesis in the context of osteogenesis imperfecta"	"Collagen biosynthesis and modifying enzymes"	"2"	"0"	"37.4"	"25.4"	"41.0"	"32.8"	"29.2"	"32.1"	"44.9"	"90.5"	"110.0"	"212.4"	"294.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H2F5"	"Enhancer of polycomb homolog 1 OS=Homo sapiens OX=9606 GN=EPC1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"836"	"93.4"	"8.59"	"330.80"	"3.87"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf06752, Pf10513"	"80314"	"ENSG00000120616"	"EPC1"	"B4DSC3; D3DRX7; hsa:80314; Q5VW54; Q5VW56; Q5VW58; Q8NAQ4; Q8NE21; Q96LF4; Q96RR6; Q9H2F5; Q9H7T7"	""	"Transcriptional Regulation by E2F6; HATs acetylate histones"	"2"	"0"	"10.2"	"33.4"	"13.5"	"9.0"	"11.5"	"4.7"	"13.5"	"22.8"	"14.4"	"40.5"	"44.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UIJ7"	"GTP:AMP phosphotransferase AK3, mitochondrial OS=Homo sapiens OX=9606 GN=AK3 PE=1 SV=4"	"0.000"	""	"5"	"1"	"2"	"1"	"227"	"25.6"	"9.16"	"391.97"	"3.87"	"1"	"1"	"other metabolic processes;stress response"	"mitochondrion;other cell component"	"kinase activity;other molecular function"	"Pf00406, Pf05191"	"50808"	"ENSG00000147853"	"AK3"	"B4DP58; D3DRI1; E7ET30; hsa:50808; Q5VYW6; Q9H576; Q9HC01; Q9NPB4; Q9UIJ7"	""	"Factors involved in megakaryocyte development and platelet production"	"1"	"0"	"8.3"	"6.1"	"6.2"	"6.0"	"4.2"	"8.5"	"7.1"	"16.4"	"25.3"	"89.1"	"262.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43929"	"Origin recognition complex subunit 4 OS=Homo sapiens OX=9606 GN=ORC4 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"436"	"50.3"	"8.00"	"392.25"	"3.87"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13191, Pf14629"	"5000"	"ENSG00000115947"	"ORC4"	"B7Z3D0; B7Z5F1; D3DP86; F5H069; hsa:5000; O43929; Q96C42"	"Cell cycle; G1 to S cell cycle control; DNA replication"	"Orc1 removal from chromatin; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; E2F-enabled inhibition of pre-replication complex formation; Assembly of the ORC complex at the origin of replication; CDC6 association with the ORC:origin complex"	"10"	"0"	"34.0"	"20.0"	"34.6"	"32.1"	"30.1"	"30.0"	"45.3"	"68.2"	"66.3"	"140.7"	"171.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95163"	"Elongator complex protein 1 OS=Homo sapiens OX=9606 GN=ELP1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1332"	"150.2"	"5.94"	"463.28"	"3.86"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04762"	"8518"	"ENSG00000070061"	"ELP1"	"hsa:8518; O95163; Q5JSV2; Q9H327; Q9UG87"	""	"HATs acetylate histones"	"1"	"0"	"30.4"	"15.5"	"22.3"	"29.2"	"28.4"	"23.2"	"30.6"	"59.3"	"54.8"	"140.4"	"213.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P27144"	"Adenylate kinase 4, mitochondrial OS=Homo sapiens OX=9606 GN=AK4 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"223"	"25.3"	"8.40"	"380.33"	"3.85"	"1"	"1"	"other metabolic processes;stress response;other biological processes"	"mitochondrion;other cell component"	"kinase activity;other molecular function"	"Pf00406, Pf05191"	"205"	"ENSG00000162433"	"AK4"	"B2R927; D3DQ62; hsa:205; P27144; Q6IBH4; Q6NXQ5; Q8IUU9"	"CCL18 signaling pathway"	"Interconversion of nucleotide di- and triphosphates"	"2"	"0"	"3.8"	"2.3"	"6.3"	"4.4"	"2.4"	"3.3"	"5.0"	"15.1"	"20.9"	"107.4"	"310.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H223"	"EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"541"	"61.1"	"6.76"	"330.01"	"3.85"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00350, Pf12763, Pf16880, Pf18150"	"30844"	"ENSG00000103966"	"EHD4"	"hsa:30844; Q9H223; Q9HAR1; Q9NZN2"	""	""	"0"	"0"	"22.3"	"18.6"	"26.6"	"26.0"	"20.2"	"24.9"	"37.0"	"117.8"	"131.9"	"271.7"	"343.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NP50"	"SIN3-HDAC complex-associated factor OS=Homo sapiens OX=9606 GN=SINHCAF PE=1 SV=1"	""	""	"10"	"1"	"1"	"1"	"221"	"24.8"	"9.41"	""	"3.85"	""	"1"	"other biological processes"	"nucleus"	""	"Pf15396"	"58516"	"ENSG00000139146; ENSG00000276371"	"SINHCAF"	"D3DUV8; hsa:58516; Q9BSZ8; Q9NP50"	""	""	"0"	"0"	"7.8"	"4.1"	"6.2"	"8.0"	"9.5"	"9.5"	"8.0"	"15.5"	"13.1"	"32.2"	"40.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HD47"	"Ran guanine nucleotide release factor OS=Homo sapiens OX=9606 GN=RANGRF PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"186"	"20.4"	"4.94"	"424.18"	"3.84"	"1"	"1"	"transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf04603"	"29098"	"ENSG00000108961"	"RANGRF"	"D3DTR6; hsa:29098; Q68DI3; Q9BR68; Q9HD47; Q9HD48; Q9NRU9; Q9P001; Q9P0P2"	""	"Phase 0 - rapid depolarisation"	"1"	"0"	"9.7"	"7.3"	"7.7"	"8.8"	"6.2"	"3.9"	"10.5"	"15.5"	"12.5"	"26.9"	"32.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O00469"	"Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 OS=Homo sapiens OX=9606 GN=PLOD2 PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"737"	"84.6"	"6.71"	""	"3.84"	""	"1"	"protein metabolism;other metabolic processes;stress response"	"other membranes;ER/Golgi"	"other molecular function"	"Pf03171"	"5352"	"ENSG00000152952"	"PLOD2"	"B3KWS3; hsa:5352; O00469; Q59ED2; Q8N170"	"Clear cell renal cell carcinoma pathways; Type I collagen synthesis in the context of osteogenesis imperfecta"	"Collagen biosynthesis and modifying enzymes"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62310"	"U6 snRNA-associated Sm-like protein LSm3 OS=Homo sapiens OX=9606 GN=LSM3 PE=1 SV=2"	"0.000"	""	"9"	"2"	"3"	"2"	"102"	"11.8"	"4.70"	"552.90"	"3.84"	"2"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01423"	"27258"	"ENSG00000170860"	"LSM3"	"hsa:27258; P62310; Q6IAH0; Q9Y4Z1"	""	"mRNA Splicing - Major Pathway; mRNA decay by 5' to 3' exoribonuclease"	"2"	"0"	"108.2"	"57.7"	"134.7"	"97.9"	"108.8"	"111.1"	"136.9"	"230.5"	"205.8"	"448.2"	"727.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P20936"	"Ras GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RASA1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1047"	"116.3"	"6.54"	"313.36"	"3.83"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00017, Pf00018, Pf00168, Pf00169, Pf00616"	"5921"	"ENSG00000145715"	"RASA1"	"B2R6W3; B4DTL2; hsa:5921; P20936; Q68CU6; Q9UDI1"	"Androgen receptor network in prostate cancer; PDGF pathway; T cell receptor and co-stimulatory signaling; Hepatocyte growth factor receptor signaling; RAC1/PAK1/p38/MMP2 pathway; MAPK signaling pathway; Ras signaling; Acute viral myocarditis; EGF/EGFR signaling pathway; GDNF signaling; EPO receptor signaling"	"Downstream signal transduction; Regulation of RAS by GAPs; EPHB-mediated forward signaling; VEGFR2 mediated cell proliferation; PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"	"16"	"0"	"3.9"	"2.8"	"8.3"	"7.7"	"6.6"	"6.1"	"7.4"	"76.1"	"104.1"	"333.5"	"492.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N4J0"	"Carnosine N-methyltransferase OS=Homo sapiens OX=9606 GN=CARNMT1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"409"	"47.2"	"6.32"	"405.53"	"3.83"	"1"	"1"	"other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf07942"	"138199"	"ENSG00000156017"	"CARNMT1"	"hsa:138199; Q7Z383; Q8N4J0; Q8N7C5"	""	"Histidine catabolism"	"1"	"0"	"8.7"	"6.7"	"10.2"	"7.8"	"6.2"	"8.4"	"10.7"	"24.3"	"24.0"	"79.4"	"109.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43435"	"T-box transcription factor TBX1 OS=Homo sapiens OX=9606 GN=TBX1 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"398"	"43.1"	"8.16"	"366.01"	"3.82"	"1"	"1"	"cell cycle OR cell proliferation;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00907"	"6899"	"ENSG00000184058"	"TBX1"	"C6G493; C6G494; hsa:6899; O43435; O43436; Q96RJ2"	"Heart development; Mesodermal commitment pathway; Mesodermal commitment pathway; FTO obesity variant mechanism; 22q11.2 copy number variation syndrome"	"Cardiogenesis"	"6"	"0"	"23.9"	"24.3"	"33.7"	"25.8"	"24.7"	"17.6"	"27.8"	"40.8"	"46.8"	"69.5"	"75.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UGJ0"	"5'-AMP-activated protein kinase subunit gamma-2 OS=Homo sapiens OX=9606 GN=PRKAG2 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"569"	"63.0"	"9.35"	"447.01"	"3.82"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00571"	"51422"	"ENSG00000106617"	"PRKAG2"	"hsa:51422; Q53Y07; Q6NUI0; Q75MP4; Q9NUZ9; Q9UDN8; Q9UGJ0; Q9ULX8"	"AMP-activated protein kinase signaling; Target of rapamycin signaling; Energy metabolism; Sterol regulatory element-binding proteins (SREBP) signaling; Ectoderm differentiation; Angiopoietin-like protein 8 regulatory pathway; Lipid metabolism pathway; Thermogenesis; Nonalcoholic fatty liver disease; Synaptic signaling pathways associated with autism spectrum disorder; Hippo signaling regulation pathways; 1q21.1 copy number variation syndrome; Autophagy; p53 transcriptional gene network; Pleural mesothelioma"	"Regulation of TP53 Activity through Phosphorylation; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Activation of AMPK downstream of NMDARs; TP53 Regulates Metabolic Genes; Carnitine metabolism; Macroautophagy; Energy dependent regulation of mTOR by LKB1-AMPK; AMPK inhibits chREBP transcriptional activation activity; Activation of PPARGC1A (PGC-1alpha) by phosphorylation; Lipophagy"	"25"	"0"	"35.4"	"39.7"	"40.4"	"42.6"	"42.2"	"39.3"	"52.2"	"88.9"	"108.5"	"266.8"	"404.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14908"	"PDZ domain-containing protein GIPC1 OS=Homo sapiens OX=9606 GN=GIPC1 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"333"	"36.0"	"6.28"	"506.60"	"3.82"	"1"	"1"	"cell-cell signaling;transport;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00595"	"10755"	"ENSG00000123159"	"GIPC1"	"A8K4I3; A8MZG3; hsa:10755; O14908; Q9BTC9"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"10.1"	"7.4"	"10.2"	"8.0"	"7.8"	"6.2"	"10.0"	"13.0"	"14.5"	"23.2"	"46.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6ZW49"	"PAX-interacting protein 1 OS=Homo sapiens OX=9606 GN=PAXIP1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1069"	"121.3"	"6.70"	"468.03"	"3.81"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	""	"Pf00533, Pf12738"	"22976"	"ENSG00000157212"	"PAXIP1"	"hsa:22976; O15404; Q6N099; Q6ZW49; Q6ZWH9; Q7Z315; Q86UN0; Q8N4P9; Q96HP2"	"16p11.2 proximal deletion syndrome; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; Kleefstra syndrome"	"Nonhomologous End-Joining (NHEJ); Activation of anterior HOX genes in hindbrain development during early embryogenesis; Formation of WDR5-containing histone-modifying complexes"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y535"	"DNA-directed RNA polymerase III subunit RPC8 OS=Homo sapiens OX=9606 GN=POLR3H PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"204"	"22.9"	"4.58"	"457.61"	"3.81"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;stress response"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03876, Pf08292"	"171568"	"ENSG00000100413"	"POLR3H"	"B0QYH9; hsa:171568; Q5M7Y8; Q96AE3; Q9BY95; Q9Y535"	"Pyrimidine metabolism; Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway; Primary ovarian insufficiency"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation"	"11"	"0"	"7.6"	"5.5"	"5.8"	"8.4"	"6.7"	"9.2"	"13.0"	"16.2"	"20.1"	"40.5"	"74.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P00568"	"Adenylate kinase isoenzyme 1 OS=Homo sapiens OX=9606 GN=AK1 PE=1 SV=3"	""	""	"6"	"1"	"1"	"1"	"194"	"21.6"	"8.63"	""	"3.81"	""	"1"	"other metabolic processes"	"cytosol;cytoskeleton;other cell component"	"kinase activity;other molecular function"	"Pf00406"	"203"	"ENSG00000106992"	"AK1"	"hsa:203; P00568; Q9BVK9; Q9UQC7"	""	"Interconversion of nucleotide di- and triphosphates"	"1"	"0"	"4.1"	"4.8"	"9.3"	"9.6"	"5.9"	"7.9"	"9.1"	"25.6"	"28.2"	"121.8"	"312.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UL63"	"Muskelin OS=Homo sapiens OX=9606 GN=MKLN1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"735"	"84.7"	"6.34"	"424.59"	"3.81"	"1"	"1"	"cell adhesion;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01344, Pf06588, Pf13415"	"4289"	"ENSG00000128585"	"MKLN1"	"A4D1M8; A6NG43; hsa:4289; Q9NSK4; Q9NUS8; Q9UL63"	"Ciliary landscape"	""	"1"	"0"	"7.4"	"4.0"	"7.1"	"8.3"	"5.6"	"8.8"	"10.1"	"17.4"	"14.7"	"34.3"	"67.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H2G2"	"STE20-like serine/threonine-protein kinase OS=Homo sapiens OX=9606 GN=SLK PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1235"	"142.6"	"5.15"	"372.86"	"3.80"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf12474"	"9748"	"ENSG00000065613"	"SLK"	"D3DRA0; D3DRA1; hsa:9748; O00211; Q6P1Z4; Q86WU7; Q86WW1; Q92603; Q9H2G2; Q9NQL0; Q9NQL1"	"TAR syndrome"	"RHOA GTPase cycle; RHOC GTPase cycle; RHOB GTPase cycle"	"4"	"0"	"57.2"	"35.5"	"74.8"	"57.1"	"59.2"	"56.3"	"68.5"	"101.5"	"110.7"	"314.2"	"410.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NYK5"	"39S ribosomal protein L39, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL39 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"338"	"38.7"	"7.65"	"334.34"	"3.80"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	""	"54148"	"ENSG00000154719"	"MRPL39"	"C9JYA5; hsa:54148; Q32Q74; Q5QTR3; Q96Q65; Q9BSQ7; Q9BZV6; Q9NX44; Q9NYK5"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"18.7"	"18.1"	"18.9"	"22.6"	"15.9"	"13.6"	"22.9"	"119.7"	"118.9"	"437.4"	"656.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94903"	"Pyridoxal phosphate homeostasis protein OS=Homo sapiens OX=9606 GN=PLPBP PE=1 SV=1"	"0.000"	""	"8"	"2"	"3"	"2"	"275"	"30.3"	"7.50"	"596.82"	"3.79"	"2"	"1"	""	"cytosol;other cell component"	"other molecular function"	"Pf01168"	"11212"	"ENSG00000147471"	"PLPBP"	"hsa:11212; O94903; Q6FI94"	""	""	"0"	"0"	"206.2"	"160.6"	"213.3"	"173.2"	"167.5"	"182.7"	"240.1"	"943.7"	"907.6"	"2747.0"	"2602.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N300"	"Small vasohibin-binding protein OS=Homo sapiens OX=9606 GN=SVBP PE=1 SV=1"	"0.000"	""	"23"	"1"	"2"	"1"	"66"	"7.8"	"9.16"	"361.88"	"3.78"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;transport;developmental processes;other biological processes"	"non-structural extracellular;cytoskeleton;other cell component"	"enzyme regulator activity;cytoskeletal activity"	"Pf15674"	"374969"	"ENSG00000177868"	"SVBP"	"A8K5P1; D3DPW7; hsa:374969; Q8N300"	""	"Carboxyterminal post-translational modifications of tubulin"	"1"	"0"	"42.3"	"34.3"	"45.9"	"47.3"	"46.8"	"45.8"	"65.5"	"155.5"	"150.3"	"247.6"	"246.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q00403"	"Transcription initiation factor IIB OS=Homo sapiens OX=9606 GN=GTF2B PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"316"	"34.8"	"8.35"	"422.30"	"3.78"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00382, Pf08271"	"2959"	"ENSG00000137947"	"GTF2B"	"A8K1A7; hsa:2959; Q00403; Q5JS30"	"Eukaryotic transcription initiation"	"RNA Polymerase II Pre-transcription Events; RNA polymerase II transcribes snRNA genes; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation"	"10"	"0"	"9.7"	"11.8"	"9.0"	"9.2"	"9.5"	"9.5"	"12.0"	"22.9"	"21.3"	"34.8"	"20.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22670"	"MHC class II regulatory factor RFX1 OS=Homo sapiens OX=9606 GN=RFX1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"979"	"104.7"	"6.29"	"319.35"	"3.78"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02257, Pf04589"	"5989"	"ENSG00000132005; ENSG00000288283"	"RFX1"	"hsa:5989; P22670"	"Alstrom syndrome"	""	"1"	"0"	"26.5"	"18.2"	"30.8"	"21.9"	"31.6"	"33.3"	"25.2"	"66.4"	"74.2"	"205.3"	"387.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H7E2"	"Tudor domain-containing protein 3 OS=Homo sapiens OX=9606 GN=TDRD3 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"651"	"73.1"	"9.23"	"363.81"	"3.78"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00567, Pf00627, Pf08585"	"81550"	"ENSG00000083544"	"TDRD3"	"B2MWP9; hsa:81550; Q53XA6; Q6P992; Q9H7E2"	""	""	"0"	"0"	"5.9"	"4.6"	"4.9"	"3.4"	"3.3"	"3.0"	"6.0"	"7.7"	"10.9"	"26.6"	"41.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51946"	"Cyclin-H OS=Homo sapiens OX=9606 GN=CCNH PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"323"	"37.6"	"7.15"	"349.15"	"3.77"	"1"	"1"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"enzyme regulator activity"	"Pf00134, Pf16899"	"902"	"ENSG00000134480"	"CCNH"	"hsa:902; P51946; Q53X72; Q8TBL9"	"Cell cycle; Eukaryotic transcription initiation; G1 to S cell cycle control; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"RUNX1 regulates transcription of genes involved in differentiation of HSCs; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; Formation of the Early Elongation Complex; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; Cyclin D associated events in G1; Cyclin A/B1/B2 associated events during G2/M transition; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Formation of Incision Complex in GG-NER; Cyclin E associated events during G1/S transition ; Cyclin A:Cdk2-associated events at S phase entry"	"39"	"0"	"8.7"	"4.3"	"15.0"	"7.8"	"6.0"	"8.2"	"12.7"	"68.8"	"68.7"	"214.2"	"288.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15021"	"Condensin complex subunit 1 OS=Homo sapiens OX=9606 GN=NCAPD2 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1401"	"157.1"	"6.61"	"348.81"	"3.76"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf12717, Pf12922"	"9918"	"ENSG00000010292"	"NCAPD2"	"D3DUR4; hsa:9918; Q15021; Q8N6U3"	""	"Condensation of Prometaphase Chromosomes"	"1"	"0"	"18.1"	"16.4"	"24.4"	"21.5"	"21.2"	"21.3"	"24.0"	"62.6"	"64.2"	"185.6"	"228.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95985"	"DNA topoisomerase 3-beta-1 OS=Homo sapiens OX=9606 GN=TOP3B PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"862"	"96.6"	"8.12"	"413.97"	"3.75"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01131, Pf01751"	"8940"	"ENSG00000100038"	"TOP3B"	"A0M8Q3; hsa:8940; O95985; Q9BUP5"	""	""	"0"	"0"	"8.3"	"10.3"	"8.9"	"11.8"	"13.6"	"16.3"	"13.7"	"18.5"	"22.6"	"52.1"	"87.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BV38"	"WD repeat-containing protein 18 OS=Homo sapiens OX=9606 GN=WDR18 PE=1 SV=2"	"0.000"	""	"6"	"2"	"3"	"2"	"432"	"47.4"	"6.70"	"713.18"	"3.75"	"2"	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf00400, Pf14077"	"57418"	"ENSG00000065268"	"WDR18"	"hsa:57418; O60390; Q9BV38; Q9BWR2"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"139.8"	"95.0"	"131.2"	"118.5"	"126.1"	"126.5"	"162.9"	"224.0"	"225.4"	"366.6"	"411.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H7N4"	"Splicing factor, arginine/serine-rich 19 OS=Homo sapiens OX=9606 GN=SCAF1 PE=1 SV=3"	"0.000"	""	"1"	"2"	"3"	"1"	"1312"	"139.2"	"9.25"	"592.52"	"3.75"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	""	"58506"	"ENSG00000126461"	"SCAF1"	"hsa:58506; Q7Z5V7; Q8WVA1; Q9H7N4; Q9NR59"	""	""	"0"	"0"	"109.0"	"90.6"	"121.7"	"100.7"	"97.6"	"97.1"	"133.3"	"165.7"	"141.7"	"221.6"	"335.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5C9Z4"	"Nucleolar MIF4G domain-containing protein 1 OS=Homo sapiens OX=9606 GN=NOM1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"860"	"96.2"	"8.10"	"315.61"	"3.74"	"1"	"1"	"other biological processes"	"nucleus"	""	"Pf02847, Pf02854"	"64434"	"ENSG00000146909"	"NOM1"	"hsa:64434; Q5C9Z4; Q96I08"	""	""	"0"	"0"	"29.9"	"26.5"	"45.1"	"36.6"	"39.6"	"37.3"	"43.0"	"80.4"	"85.6"	"189.6"	"237.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q63HQ0"	"AP-1 complex-associated regulatory protein OS=Homo sapiens OX=9606 GN=AP1AR PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"302"	"34.3"	"4.87"	"388.01"	"3.74"	"1"	"1"	"cell adhesion;transport;other biological processes"	"cytosol;ER/Golgi;other cytoplasmic organelle"	"cytoskeletal activity;other molecular function"	"Pf15745"	"55435"	"ENSG00000138660"	"AP1AR"	"B2RCV7; hsa:55435; Q63HQ0; Q96GG6; Q9H0V0; Q9P1L4"	""	""	"0"	"0"	"12.9"	"6.3"	"12.7"	"10.9"	"10.6"	"17.2"	"10.7"	"32.7"	"30.7"	"65.3"	"113.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P85037"	"Forkhead box protein K1 OS=Homo sapiens OX=9606 GN=FOXK1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"733"	"75.4"	"9.32"	"369.69"	"3.74"	"1"	"1"	"other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00250, Pf00498"	"221937"	"ENSG00000164916"	"FOXK1"	"hsa:221937; P85037"	""	"UCH proteinases"	"1"	"0"	"29.5"	"18.1"	"29.8"	"28.1"	"33.6"	"16.7"	"31.5"	"57.4"	"63.8"	"146.6"	"236.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NZN8"	"CCR4-NOT transcription complex subunit 2 OS=Homo sapiens OX=9606 GN=CNOT2 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"540"	"59.7"	"7.66"	"415.91"	"3.73"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf04153"	"4848"	"ENSG00000111596"	"CNOT2"	"hsa:4848; Q9H3E0; Q9NSX5; Q9NWR6; Q9NZN8; Q9P028"	""	"Deadenylation of mRNA; TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07741"	"Adenine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=APRT PE=1 SV=2"	"0.000"	""	"10"	"1"	"2"	"1"	"180"	"19.6"	"6.02"	"293.00"	"3.71"	"1"	"1"	"other metabolic processes;transport;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00156"	"353"	"ENSG00000198931"	"APRT"	"G5E9J2; hsa:353; P07741; Q3KP55; Q68DF9"	""	"Neutrophil degranulation; Purine salvage; Defective APRT disrupts adenine salvage"	"3"	"0"	"11.3"	"8.4"	"14.6"	"11.3"	"14.4"	"15.5"	"15.4"	"30.4"	"33.5"	"92.1"	"121.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H9F9"	"Actin-related protein 5 OS=Homo sapiens OX=9606 GN=ACTR5 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"607"	"68.3"	"5.27"	"291.98"	"3.71"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	""	"Pf00022"	"79913"	"ENSG00000101442"	"ACTR5"	"hsa:79913; Q86WF7; Q8IUY5; Q8N724; Q9BRN0; Q9BVB7; Q9H9F9"	""	"UCH proteinases; DNA Damage Recognition in GG-NER"	"2"	"0"	"21.8"	"16.7"	"24.7"	"16.9"	"18.9"	"18.4"	"24.7"	"61.4"	"70.4"	"227.2"	"271.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14579"	"Coatomer subunit epsilon OS=Homo sapiens OX=9606 GN=COPE PE=1 SV=3"	"0.000"	""	"6"	"1"	"2"	"1"	"308"	"34.5"	"5.12"	"376.32"	"3.70"	"1"	"1"	"transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus"	"other molecular function"	"Pf04733"	"11316"	"ENSG00000105669"	"COPE"	"A6NE29; A6NKA3; hsa:11316; O14579; O76097; Q6IBB8; Q9UGP6"	""	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport"	"2"	"0"	"31.8"	"24.7"	"36.1"	"35.8"	"33.1"	"38.4"	"48.4"	"159.4"	"146.1"	"477.1"	"657.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15057"	"Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ACAP2 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"778"	"88.0"	"6.80"	"379.65"	"3.70"	"1"	"1"	"transport;other biological processes"	"other membranes;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf01412, Pf12796, Pf16746"	"23527"	"ENSG00000114331"	"ACAP2"	"A8K2V4; hsa:23527; Q15057; Q8N5Z8; Q9UQR3"	""	""	"0"	"0"	"27.2"	"28.4"	"28.1"	"27.6"	"33.3"	"49.0"	"68.3"	"117.4"	"117.2"	"249.6"	"311.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UJ83"	"2-hydroxyacyl-CoA lyase 1 OS=Homo sapiens OX=9606 GN=HACL1 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"578"	"63.7"	"7.36"	"558.43"	"3.70"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00205, Pf02775, Pf02776"	"26061"	"ENSG00000131373"	"HACL1"	"B4DWI1; B4DXI5; E9PEN4; hsa:26061; Q9BV42; Q9P0A2; Q9UJ83"	""	"Peroxisomal protein import; Alpha-oxidation of phytanate"	"2"	"0"	"24.7"	"19.0"	"56.2"	"28.7"	"26.2"	"23.8"	"38.9"	"123.4"	"149.6"	"225.5"	"261.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NVS2"	"39S ribosomal protein S18a, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS18A PE=1 SV=1"	""	""	"8"	"1"	"1"	"1"	"196"	"22.2"	"10.33"	""	"3.69"	""	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf01084"	"55168"	"ENSG00000096080"	"MRPS18A"	"A6XND3; hsa:55168; Q5QPA4; Q9NVS2"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14770"	"Homeobox protein Meis2 OS=Homo sapiens OX=9606 GN=MEIS2 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"477"	"51.8"	"6.40"	"396.82"	"3.68"	"1"	"1"	"developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05920, Pf16493"	"4212"	"ENSG00000134138"	"MEIS2"	"A6NJI5; A8MWD5; B3KP98; B3KPQ6; hsa:4212; O14770; Q96DI2; Q96KI4; Q96KI5; Q9NRS1; Q9NRS2; Q9NRS3"	""	""	"0"	"0"	"10.1"	"9.3"	"12.1"	"10.4"	"10.6"	"7.9"	"12.0"	"22.4"	"16.4"	"45.2"	"65.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EY5"	"Multivesicular body subunit 12A OS=Homo sapiens OX=9606 GN=MVB12A PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"273"	"28.8"	"8.91"	"343.70"	"3.68"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf10240"	"93343"	"ENSG00000141971"	"MVB12A"	"hsa:93343; Q96EY5; Q96I18"	"7q11.23 copy number variation syndrome"	"Budding and maturation of HIV virion; Membrane binding and targetting of GAG proteins; Endosomal Sorting Complex Required For Transport (ESCRT); Late endosomal microautophagy; HCMV Late Events"	"6"	"0"	"26.1"	"19.9"	"24.7"	"19.5"	"31.6"	"33.0"	"54.6"	"144.5"	"147.0"	"361.6"	"435.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13797"	"Plastin-3 OS=Homo sapiens OX=9606 GN=PLS3 PE=1 SV=4"	"0.000"	""	"2"	"1"	"2"	"1"	"630"	"70.8"	"5.60"	"410.06"	"3.67"	"1"	"1"	"cell organization and biogenesis;developmental processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf13499"	"5358"	"ENSG00000102024"	"PLS3"	"A8K579; B1AQ09; B4DGB4; B7Z6M1; hsa:5358; P13797; Q86YI6"	""	""	"0"	"0"	"33.7"	"34.6"	"54.1"	"42.5"	"33.9"	"28.0"	"31.9"	"51.7"	"48.9"	"91.1"	"154.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NPB8"	"Glycerophosphocholine phosphodiesterase GPCPD1 OS=Homo sapiens OX=9606 GN=GPCPD1 PE=1 SV=2"	"0.000"	""	"4"	"2"	"3"	"2"	"672"	"76.0"	"5.53"	"945.95"	"3.67"	"2"	"1"	"other metabolic processes;other biological processes"	"cytosol"	"other molecular function"	"Pf00686, Pf03009"	"56261"	"ENSG00000125772"	"GPCPD1"	"D3DW06; hsa:56261; Q9BQL8; Q9NPB8; Q9NUX0"	""	"Hydrolysis of LPC; Hydrolysis of LPE"	"2"	"0"	"4.4"	"4.4"	"4.4"	"6.2"	"4.3"	"10.3"	"11.9"	"131.3"	"146.9"	"537.1"	"730.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BPU6"	"Dihydropyrimidinase-related protein 5 OS=Homo sapiens OX=9606 GN=DPYSL5 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"564"	"61.4"	"7.20"	"291.01"	"3.67"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf01979"	"56896"	"ENSG00000157851"	"DPYSL5"	"hsa:56896; Q8TCL6; Q9BPU6; Q9NQC4; Q9NRY9"	""	"CRMPs in Sema3A signaling"	"1"	"0"	"28.2"	"14.3"	"28.2"	"24.1"	"24.5"	"25.5"	"24.2"	"80.8"	"81.9"	"198.7"	"323.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P78537"	"Biogenesis of lysosome-related organelles complex 1 subunit 1 OS=Homo sapiens OX=9606 GN=BLOC1S1 PE=1 SV=2"	"0.000"	""	"7"	"1"	"2"	"1"	"153"	"17.3"	"9.33"	"413.33"	"3.67"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	""	"Pf06320"	"2647"	"ENSG00000135441"	"BLOC1S1"	"A1L4Q9; hsa:2647; P78537; Q6NZ45"	"Alstrom syndrome"	"Lysosome Vesicle Biogenesis; Golgi Associated Vesicle Biogenesis"	"3"	"0"	"2.8"	"3.9"	"5.8"	"4.3"	"4.3"	"4.9"	"11.6"	"15.1"	"19.5"	"56.0"	"109.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P0U4"	"CXXC-type zinc finger protein 1 OS=Homo sapiens OX=9606 GN=CXXC1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"656"	"75.7"	"8.24"	"367.61"	"3.66"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00628, Pf02008, Pf12269"	"30827"	"ENSG00000154832"	"CXXC1"	"B2RC03; hsa:30827; Q8N2W4; Q96BC8; Q9P0U4; Q9P2V7"	"Male infertility"	"XBP1(S) activates chaperone genes; Formation of WDR5-containing histone-modifying complexes"	"3"	"0"	"42.2"	"37.5"	"39.5"	"41.2"	"41.2"	"52.3"	"44.0"	"70.8"	"66.7"	"119.8"	"157.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P11717"	"Cation-independent mannose-6-phosphate receptor OS=Homo sapiens OX=9606 GN=IGF2R PE=1 SV=3"	""	""	"0"	"1"	"1"	"1"	"2491"	"274.2"	"5.94"	""	"3.66"	""	"1"	"transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf00040, Pf00878"	"3482"	"ENSG00000197081"	"IGF2R"	"hsa:3482; P11717; Q7Z7G9; Q96PT5"	"TROP2 regulatory signaling"	"Neutrophil degranulation; Golgi Associated Vesicle Biogenesis; Cargo recognition for clathrin-mediated endocytosis; Retrograde transport at the Trans-Golgi-Network"	"6"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"2.1"	"0.0"	"0.0"	"7.7"	"8.5"	"63.4"	"116.8"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43847"	"Nardilysin OS=Homo sapiens OX=9606 GN=NRDC PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1151"	"131.6"	"4.98"	"360.90"	"3.66"	"1"	"1"	"protein metabolism;other biological processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00675, Pf05193, Pf16187"	"4898"	"ENSG00000078618"	"NRDC"	"A6NI41; hsa:4898; O15241; O15242; O43847; Q5VUL0; Q96HB2; Q9NU57"	""	""	"0"	"0"	"8.4"	"7.0"	"7.7"	"6.3"	"4.7"	"6.5"	"8.7"	"13.5"	"11.1"	"16.2"	"29.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22314"	"Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1058"	"117.8"	"5.76"	"426.95"	"3.66"	"1"	"1"	"protein metabolism;other metabolic processes;stress response"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00899, Pf09358, Pf10585, Pf16190, Pf16191"	"7317"	"ENSG00000130985"	"UBA1"	"hsa:7317; P22314; Q5JRR8; Q96E13"	"Proteasome degradation; Parkin-ubiquitin proteasomal system pathway; Parkinson's disease pathway"	"Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Antigen processing: Ubiquitination & Proteasome degradation"	"5"	"0"	"7.5"	"9.9"	"12.6"	"13.8"	"7.1"	"9.2"	"8.3"	"26.7"	"19.4"	"47.4"	"205.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P33316"	"Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=DUT PE=1 SV=4"	"0.000"	""	"5"	"1"	"2"	"1"	"252"	"26.5"	"9.36"	"351.79"	"3.65"	"1"	"1"	"DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;mitochondrion;nucleus"	"signal transduction activity or receptor binding;other molecular function"	"Pf00692"	"1854"	"ENSG00000128951"	"DUT"	"A8K650; B4DPR5; hsa:1854; O14785; P33316; Q16708; Q16860; Q6FHN1; Q6NSA3; Q96Q81"	"Pyrimidine metabolism"	""	"1"	"0"	"4.8"	"5.5"	"8.8"	"6.8"	"6.4"	"10.5"	"9.8"	"14.1"	"23.6"	"46.7"	"85.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q93075"	"Putative deoxyribonuclease TATDN2 OS=Homo sapiens OX=9606 GN=TATDN2 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"761"	"85.0"	"7.39"	"443.97"	"3.65"	"1"	"1"	""	"nucleus"	"other molecular function"	"Pf01026"	"9797"	"ENSG00000157014"	"TATDN2"	"hsa:9797; Q3MIL9; Q5BKU0; Q93075"	""	"XBP1(S) activates chaperone genes"	"1"	"0"	"10.0"	"4.3"	"4.5"	"8.2"	"1.7"	"8.1"	"11.6"	"15.6"	"13.9"	"21.1"	"19.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P56182"	"Ribosomal RNA processing protein 1 homolog A OS=Homo sapiens OX=9606 GN=RRP1 PE=1 SV=1"	""	""	"5"	"1"	"1"	"1"	"461"	"52.8"	"9.33"	""	"3.64"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf05997"	"8568"	"ENSG00000160214"	"RRP1"	"hsa:8568; P56182; Q9NST5"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"10.4"	"7.4"	"7.4"	"6.6"	"9.0"	"4.1"	"9.0"	"9.5"	"8.8"	"23.2"	"40.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92738"	"USP6 N-terminal-like protein OS=Homo sapiens OX=9606 GN=USP6NL PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"828"	"94.0"	"9.07"	"434.28"	"3.64"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00566"	"9712"	"ENSG00000148429"	"USP6NL"	"A8KA79; hsa:9712; Q15400; Q5VV10; Q7L0K9; Q92738"	"EGF/EGFR signaling pathway"	"Retrograde transport at the Trans-Golgi-Network"	"2"	"0"	"26.2"	"25.5"	"14.9"	"18.6"	"22.8"	"21.9"	"29.1"	"35.2"	"30.4"	"47.2"	"57.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q68CP9"	"AT-rich interactive domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ARID2 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1835"	"197.3"	"7.42"	"353.50"	"3.64"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01388, Pf02257"	"196528"	"ENSG00000189079"	"ARID2"	"hsa:196528; Q15KG9; Q5EB51; Q645I3; Q68CP9; Q6ZRY5; Q7Z3I5; Q86T28; Q96SJ6; Q9HCL5"	""	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; RMTs methylate histone arginines"	"2"	"0"	"22.9"	"15.8"	"23.5"	"16.2"	"20.8"	"19.3"	"24.4"	"31.2"	"34.3"	"55.2"	"65.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IUR0"	"Trafficking protein particle complex subunit 5 OS=Homo sapiens OX=9606 GN=TRAPPC5 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"188"	"20.8"	"9.66"	"393.87"	"3.64"	"1"	"1"	"cell organization and biogenesis;transport"	"cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf04051"	"126003"	"ENSG00000181029"	"TRAPPC5"	"A8K7I6; hsa:126003; Q8IUR0"	""	"COPII-mediated vesicle transport; RAB GEFs exchange GTP for GDP on RABs"	"2"	"0"	"25.3"	"18.3"	"40.4"	"38.7"	"28.7"	"34.3"	"60.6"	"180.2"	"220.3"	"575.4"	"946.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07711"	"Cathepsin L1 OS=Homo sapiens OX=9606 GN=CTSL PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"333"	"37.5"	"5.45"	"398.37"	"3.64"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00112, Pf08246"	"1514"	"ENSG00000135047"	"CTSL"	"hsa:1514; P07711; Q6IAV1; Q96QJ0"	"Primary focal segmental glomerulosclerosis (FSGS); Ebola virus infection in host; Mitochondrial immune response to SARS-CoV-2"	"MHC class II antigen presentation; Collagen degradation; Assembly of collagen fibrils and other multimeric structures; Attachment and Entry; RUNX1 regulates transcription of genes involved in differentiation of keratinocytes; Attachment and Entry; Trafficking and processing of endosomal TLR; Endosomal/Vacuolar pathway"	"12"	"0"	"14.8"	"9.8"	"11.5"	"13.1"	"13.6"	"23.9"	"39.6"	"256.1"	"250.6"	"572.6"	"621.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H2K0"	"Translation initiation factor IF-3, mitochondrial OS=Homo sapiens OX=9606 GN=MTIF3 PE=1 SV=4"	"0.000"	""	"5"	"1"	"2"	"1"	"278"	"31.7"	"9.69"	"565.04"	"3.63"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"mitochondrion"	"translation activity;nucleic acid binding activity"	"Pf05198"	"219402"	"ENSG00000122033"	"MTIF3"	"hsa:219402; Q05BL8; Q5W0V0; Q86X68; Q9H2K0"	""	"Mitochondrial translation initiation"	"1"	"0"	"174.0"	"144.4"	"174.0"	"155.1"	"170.0"	"171.2"	"197.5"	"295.1"	"284.8"	"385.9"	"342.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16342"	"Programmed cell death protein 2 OS=Homo sapiens OX=9606 GN=PDCD2 PE=1 SV=2"	"0.000"	""	"5"	"1"	"2"	"1"	"344"	"38.6"	"5.38"	"397.06"	"3.63"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01753, Pf04194"	"5134"	"ENSG00000071994"	"PDCD2"	"E9PCU7; F5GYS7; hsa:5134; Q16342; Q58HM9; Q58HN0; Q9UH12"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P54098"	"DNA polymerase subunit gamma-1 OS=Homo sapiens OX=9606 GN=POLG PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"1239"	"139.5"	"6.90"	"419.69"	"3.63"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response"	"mitochondrion;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00476, Pf18136"	"5428"	"ENSG00000140521"	"POLG"	"hsa:5428; P54098; Q8NFM2; Q92515"	"Male infertility; Primary ovarian insufficiency"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13674"	"Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2"	"0.000"	""	"5"	"2"	"3"	"2"	"534"	"61.0"	"6.01"	"675.57"	"3.63"	"2"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"ER/Golgi;other cell component"	"other molecular function"	"Pf08336, Pf13640"	"5033"	"ENSG00000122884"	"P4HA1"	"C9JL12; hsa:5033; P13674; Q15082; Q15083; Q5VSQ5"	"Type I collagen synthesis in the context of osteogenesis imperfecta"	"Collagen biosynthesis and modifying enzymes"	"2"	"0"	"86.7"	"64.2"	"96.4"	"81.9"	"70.2"	"70.0"	"110.3"	"192.8"	"177.6"	"368.7"	"521.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07737"	"Profilin-1 OS=Homo sapiens OX=9606 GN=PFN1 PE=1 SV=2"	"0.000"	""	"11"	"1"	"2"	"1"	"140"	"15.0"	"8.27"	"311.29"	"3.62"	"1"	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00235"	"5216"	"ENSG00000108518"	"PFN1"	"hsa:5216; P07737; Q53Y44"	"Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; Burn wound healing; Regulation of actin cytoskeleton; G13 signaling pathway"	"RHO GTPases Activate Formins; Platelet degranulation ; PCP/CE pathway; Signaling by ROBO receptors"	"9"	"0"	"42.2"	"61.6"	"58.7"	"46.0"	"43.8"	"35.7"	"41.2"	"76.7"	"63.3"	"110.5"	"194.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13614"	"Myotubularin-related protein 2 OS=Homo sapiens OX=9606 GN=MTMR2 PE=1 SV=4"	"0.000"	""	"3"	"1"	"2"	"1"	"643"	"73.3"	"7.40"	"341.68"	"3.62"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf02893, Pf06602"	"8898"	"ENSG00000087053"	"MTMR2"	"A6NN98; hsa:8898; Q13614; Q9UPS9"	"Intracellular trafficking proteins involved in CMT neuropathy"	"Synthesis of PIPs at the ER membrane; Synthesis of PIPs at the plasma membrane; Synthesis of PIPs at the early endosome membrane; Synthesis of PIPs at the late endosome membrane"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9ULM3"	"YEATS domain-containing protein 2 OS=Homo sapiens OX=9606 GN=YEATS2 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1422"	"150.7"	"8.98"	"396.20"	"3.61"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf03366"	"55689"	"ENSG00000163872"	"YEATS2"	"A7E2B9; D3DNS9; hsa:55689; Q641P6; Q9NW96; Q9ULM3"	""	"Formation of WDR5-containing histone-modifying complexes; HATs acetylate histones"	"2"	"0"	"4.9"	"7.7"	"2.8"	"3.8"	"3.7"	"4.0"	"4.9"	"17.2"	"16.9"	"54.7"	"95.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N806"	"Putative E3 ubiquitin-protein ligase UBR7 OS=Homo sapiens OX=9606 GN=UBR7 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"425"	"48.0"	"4.81"	"445.61"	"3.60"	"1"	"1"	"protein metabolism;other metabolic processes"	""	"other molecular function"	"Pf02207"	"55148"	"ENSG00000012963; ENSG00000278787"	"UBR7"	"hsa:55148; Q86U21; Q86UA9; Q8N806; Q96BY0; Q9NVV6"	""	""	"0"	"0"	"17.6"	"10.4"	"15.4"	"25.1"	"14.5"	"18.7"	"18.3"	"38.2"	"34.4"	"116.1"	"188.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96PE7"	"Methylmalonyl-CoA epimerase, mitochondrial OS=Homo sapiens OX=9606 GN=MCEE PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"176"	"18.7"	"9.09"	"475.39"	"3.60"	"1"	"1"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf13669"	"84693"	"ENSG00000124370"	"MCEE"	"hsa:84693; Q53TP1; Q8WW63; Q96PE7"	"Vitamin B12 metabolism"	"Propionyl-CoA catabolism"	"2"	"0"	"19.9"	"11.1"	"26.3"	"23.6"	"26.0"	"18.7"	"27.9"	"59.2"	"70.9"	"180.7"	"247.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y530"	"ADP-ribose glycohydrolase OARD1 OS=Homo sapiens OX=9606 GN=OARD1 PE=1 SV=2"	"0.000"	""	"8"	"1"	"2"	"1"	"152"	"17.0"	"8.31"	"333.23"	"3.60"	"1"	"1"	"protein metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf01661"	"221443"	"ENSG00000124596"	"OARD1"	"A6NEK4; A8K4H4; hsa:221443; Q96F23; Q9Y530"	""	""	"0"	"0"	"40.6"	"26.8"	"46.7"	"38.6"	"36.7"	"38.0"	"54.1"	"125.4"	"122.3"	"297.3"	"335.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75312"	"Zinc finger protein ZPR1 OS=Homo sapiens OX=9606 GN=ZPR1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"459"	"50.9"	"4.73"	"436.92"	"3.60"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf03367"	"8882"	"ENSG00000109917"	"ZPR1"	"hsa:8882; O75312; Q2TAA0"	""	""	"0"	"0"	"58.0"	"39.3"	"50.4"	"51.8"	"41.1"	"49.8"	"61.7"	"86.7"	"82.4"	"155.1"	"229.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05204"	"Non-histone chromosomal protein HMG-17 OS=Homo sapiens OX=9606 GN=HMGN2 PE=1 SV=3"	"0.000"	""	"20"	"1"	"2"	"1"	"90"	"9.4"	"9.99"	"409.64"	"3.60"	"1"	"1"	"cell organization and biogenesis;stress response;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01101"	"3151"	"ENSG00000198830"	"HMGN2"	"hsa:3151; P05204; Q0VGD5; Q6FGI5; Q96C64"	""	""	"0"	"0"	"74.2"	"64.2"	"64.9"	"50.1"	"59.6"	"70.0"	"75.0"	"70.8"	"63.6"	"73.6"	"97.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VVJ2"	"Histone H2A deubiquitinase MYSM1 OS=Homo sapiens OX=9606 GN=MYSM1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"828"	"95.0"	"5.53"	"448.98"	"3.59"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00249, Pf01398, Pf04433"	"114803"	"ENSG00000162601"	"MYSM1"	"A8KA54; B3KX65; hsa:114803; Q5VVJ2; Q68DD3; Q6AI53; Q7Z3G8; Q96PX3"	""	"Metalloprotease DUBs"	"1"	"0"	"0.0"	"2.8"	"4.4"	"1.9"	"3.3"	"0.0"	"2.8"	"11.1"	"15.9"	"49.3"	"56.9"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8ND76"	"Cyclin-Y OS=Homo sapiens OX=9606 GN=CCNY PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"341"	"39.3"	"7.20"	"325.69"	"3.59"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;signal transduction;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00134"	"219771"	"ENSG00000108100"	"CCNY"	"B7ZKX9; D3DRY9; hsa:219771; Q2M3V4; Q2TU96; Q6NT86; Q7Z4U7; Q8ND76; Q8TEX2; Q8TEX3; Q96M99; Q96P45"	""	""	"0"	"0"	"6.5"	"5.7"	"9.8"	"6.7"	"5.4"	"5.2"	"7.5"	"27.6"	"30.8"	"105.3"	"154.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9ULH7"	"Myocardin-related transcription factor B OS=Homo sapiens OX=9606 GN=MRTFB PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"1088"	"118.1"	"6.28"	"546.20"	"3.58"	"1"	"1"	"other biological processes"	"nucleus"	"other molecular function"	"Pf02037, Pf02755"	"57496"	"ENSG00000186260"	"MRTFB"	"A6ND53; B4DGT8; hsa:57496; Q68CT1; Q6UB16; Q86WW2; Q8N226; Q9ULH7"	""	""	"0"	"0"	"78.3"	"50.8"	"59.4"	"60.7"	"51.6"	"64.9"	"79.3"	"78.2"	"87.5"	"112.0"	"133.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6Y288"	"Beta-1,3-glucosyltransferase OS=Homo sapiens OX=9606 GN=B3GLCT PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"498"	"56.5"	"7.50"	"296.09"	"3.58"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf02434"	"145173"	"ENSG00000187676"	"B3GLCT"	"A8K5F8; hsa:145173; Q5W0H2; Q6NUI3; Q6Y288"	""	"Defective B3GALTL causes PpS; O-glycosylation of TSR domain-containing proteins"	"2"	"0"	"11.0"	"6.3"	"15.1"	"16.0"	"12.3"	"18.3"	"25.4"	"91.0"	"81.0"	"251.9"	"345.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BTZ2"	"Dehydrogenase/reductase SDR family member 4 OS=Homo sapiens OX=9606 GN=DHRS4 PE=1 SV=3"	"0.000"	""	"5"	"1"	"2"	"1"	"278"	"29.5"	"8.56"	"498.21"	"3.57"	"1"	"1"	"other metabolic processes;other biological processes"	"other membranes;cytosol;mitochondrion;ER/Golgi;nucleus;other cytoplasmic organelle"	"other molecular function"	"Pf13561"	"10901"	"ENSG00000157326; ENSG00000284807"	"DHRS4"	"B2RB10; B7WNS9; D3YTB8; E2QRL8; hsa:10901; O95162; Q20CR0; Q2LC19; Q2LE81; Q58IU4; Q6E0Y1; Q6UWU3; Q71UQ6; Q8TD03; Q9BTZ2; Q9H3N5; Q9NV08"	""	"Peroxisomal protein import; RA biosynthesis pathway"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6ZYL4"	"General transcription factor IIH subunit 5 OS=Homo sapiens OX=9606 GN=GTF2H5 PE=1 SV=1"	"0.000"	""	"21"	"1"	"2"	"1"	"71"	"8.0"	"4.65"	"364.96"	"3.57"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	""	"Pf06331"	"404672"	"ENSG00000272047"	"GTF2H5"	"hsa:404672; Q0P5V8; Q6ZYL4"	"Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"NoRC negatively regulates rRNA expression; TP53 Regulates Transcription of DNA Repair Genes; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Dual Incision in GG-NER"	"32"	"0"	"23.0"	"17.9"	"16.0"	"17.1"	"20.8"	"22.9"	"32.7"	"73.0"	"68.7"	"115.6"	"152.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60318"	"Germinal-center associated nuclear protein OS=Homo sapiens OX=9606 GN=MCM3AP PE=1 SV=2"	"0.000"	""	"2"	"2"	"3"	"2"	"1980"	"218.3"	"6.39"	"772.41"	"3.56"	"2"	"1"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03399, Pf16766, Pf16768, Pf16769"	"8888"	"ENSG00000160294"	"MCM3AP"	"C9JL56; hsa:8888; O60318; Q2M3C1; Q6PJP6; Q9BSY5; Q9UMT4"	""	""	"0"	"0"	"54.5"	"33.4"	"52.7"	"52.2"	"46.3"	"51.6"	"84.7"	"114.9"	"163.6"	"236.2"	"313.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9H488"	"GDP-fucose protein O-fucosyltransferase 1 OS=Homo sapiens OX=9606 GN=POFUT1 PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"388"	"43.9"	"8.53"	""	"3.56"	""	"1"	"protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf10250"	"23509"	"ENSG00000101346"	"POFUT1"	"A8K4R8; E1P5M4; hsa:23509; Q14685; Q5W185; Q9BW76; Q9H488"	""	"Pre-NOTCH Processing in the Endoplasmic Reticulum"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P43686"	"26S proteasome regulatory subunit 6B OS=Homo sapiens OX=9606 GN=PSMC4 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"418"	"47.3"	"5.21"	"371.35"	"3.56"	"1"	"1"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf16450, Pf17862"	"5704"	"ENSG00000013275; ENSG00000281221"	"PSMC4"	"hsa:5704; P43686; Q96FV5; Q9UBM3; Q9UEX3"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Ciliary landscape; Alzheimer's disease"	"Ub-specific processing proteases; Regulation of RAS by GAPs; UCH proteinases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of expression of SLITs and ROBOs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"64"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15139"	"Serine/threonine-protein kinase D1 OS=Homo sapiens OX=9606 GN=PRKD1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"912"	"101.6"	"6.62"	"394.27"	"3.56"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00130, Pf00169"	"5587"	"ENSG00000184304"	"PRKD1"	"A6NL64; B2RAF6; hsa:5587; Q15139"	"Apoptosis modulation and signaling; Cardiac hypertrophic response; Myometrial relaxation and contraction pathways; G protein signaling pathways; VEGFA-VEGFR2 signaling; Wnt signaling pathway and pluripotency; Gastrin signaling pathway; Osteoblast differentiation and related diseases; Calcium regulation in cardiac cells"	"Sphingolipid de novo biosynthesis"	"10"	"0"	"11.3"	"9.4"	"11.1"	"16.4"	"13.4"	"9.8"	"14.3"	"24.9"	"27.2"	"69.5"	"82.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P82921"	"28S ribosomal protein S21, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS21 PE=1 SV=3"	"0.000"	""	"14"	"1"	"2"	"1"	"87"	"10.7"	"9.92"	"322.84"	"3.56"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf01165"	"54460"	"ENSG00000266472"	"MRPS21"	"A0A075B746; hsa:54460; P82921; Q5TB11; Q9BST6"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"38.6"	"24.3"	"34.5"	"29.8"	"28.4"	"30.0"	"41.9"	"76.3"	"68.8"	"159.5"	"241.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14727"	"Apoptotic protease-activating factor 1 OS=Homo sapiens OX=9606 GN=APAF1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1248"	"141.7"	"6.40"	"343.59"	"3.56"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00400, Pf00619, Pf00931, Pf17908"	"317"	"ENSG00000120868"	"APAF1"	"B2RMX8; hsa:317; O14727; O43297; Q7Z438; Q9BXZ6; Q9UBZ5; Q9UGN8; Q9UGN9; Q9UGP0; Q9UJ58; Q9UJ59; Q9UJ60; Q9UJ61; Q9UJ62; Q9UJ63; Q9UJ64; Q9UJ65; Q9UJ66; Q9UJ67; Q9UNC9"	"miRNA regulation of DNA damage response; Alzheimer's disease and miRNA effects; TNF-alpha signaling pathway; Parkinson's disease pathway; Amyotrophic lateral sclerosis (ALS); Nanomaterial induced apoptosis; Apoptosis; Fas ligand pathway and stress induction of heat shock proteins; Apoptosis modulation by HSP70; Oxidative damage response; miRNA regulation of p53 pathway in prostate cancer; Measles virus infection; Small cell lung cancer; Hepatitis B infection; Regucalcin in proximal tubule epithelial kidney cells; Host-pathogen interaction of human coronaviruses - apoptosis; p53 transcriptional gene network; Complement system in neuronal development and plasticity; Alzheimer's disease; CKAP4 signaling pathway map; DNA damage response"	"Neutrophil degranulation; Transcriptional Regulation by E2F6; Activation of caspases through apoptosome-mediated cleavage; SMAC (DIABLO) binds to IAPs ; SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes ; TP53 Regulates Transcription of Caspase Activators and Caspases; Regulation of the apoptosome activity"	"29"	"0"	"0.0"	"0.0"	"2.0"	"0.0"	"0.0"	"0.0"	"3.1"	"14.5"	"18.2"	"72.6"	"139.1"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30085"	"UMP-CMP kinase OS=Homo sapiens OX=9606 GN=CMPK1 PE=1 SV=3"	"0.000"	""	"10"	"2"	"3"	"2"	"196"	"22.2"	"5.57"	"677.07"	"3.55"	"2"	"1"	"other metabolic processes"	"cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00406"	"51727"	"ENSG00000162368"	"CMPK1"	"B2R6S5; B4DPU7; E9PGI8; hsa:51727; P30085; Q53GB7; Q5SVZ0; Q96C07; Q9UBQ8; Q9UIA2"	"Pyrimidine metabolism"	"Interconversion of nucleotide di- and triphosphates"	"2"	"0"	"79.1"	"58.1"	"85.7"	"78.9"	"79.9"	"79.1"	"95.7"	"143.4"	"139.7"	"329.4"	"983.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99570"	"Phosphoinositide 3-kinase regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PIK3R4 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1358"	"153.0"	"7.17"	"303.54"	"3.54"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00400"	"30849"	"ENSG00000196455"	"PIK3R4"	"hsa:30849; Q2TBF4; Q99570"	"Alzheimer's disease and miRNA effects; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Neural crest cell migration during development; Neural crest cell migration in cancer; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Osteoblast differentiation and related diseases; Ciliopathies; Insulin signaling; Autophagy; Regulation of actin cytoskeleton; Alzheimer's disease; DNA damage response (only ATM dependent)"	"SARS-CoV-2 activates/modulates innate and adaptive immune responses; Synthesis of PIPs at the Golgi membrane; Synthesis of PIPs at the early endosome membrane; Synthesis of PIPs at the late endosome membrane; PI3K Cascade; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Macroautophagy; Translation of Replicase and Assembly of the Replication Transcription Complex; Translation of Replicase and Assembly of the Replication Transcription Complex; RHO GTPases Activate NADPH Oxidases; Toll Like Receptor 9 (TLR9) Cascade"	"24"	"0"	"25.6"	"16.4"	"25.5"	"24.4"	"19.1"	"18.7"	"23.6"	"46.7"	"48.7"	"105.2"	"132.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86YM7"	"Homer protein homolog 1 OS=Homo sapiens OX=9606 GN=HOMER1 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"354"	"40.3"	"5.44"	"320.92"	"3.54"	"1"	"1"	"cell-cell signaling;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00568"	"9456"	"ENSG00000152413"	"HOMER1"	"B2R688; hsa:9456; O96003; Q86YM5; Q86YM7"	"BDNF-TrkB signaling; Synaptic signaling pathways associated with autism spectrum disorder; Fragile X syndrome; Disruption of postsynaptic signaling by CNV; Orexin receptor pathway"	"Neurexins and neuroligins"	"6"	"0"	"33.8"	"26.1"	"42.9"	"39.8"	"35.0"	"43.3"	"46.7"	"91.0"	"82.1"	"165.2"	"232.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49005"	"DNA polymerase delta subunit 2 OS=Homo sapiens OX=9606 GN=POLD2 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"469"	"51.3"	"5.58"	"316.76"	"3.53"	"1"	"1"	"DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf04042, Pf18018"	"5425"	"ENSG00000106628"	"POLD2"	"A4D2J4; B2R5S4; hsa:5425; P49005"	"Homologous recombination; Pyrimidine metabolism; DNA replication; Base excision repair; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Removal of the Flap Intermediate; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta); Polymerase switching on the C-strand of the telomere; Polymerase switching"	"25"	"0"	"51.9"	"29.7"	"65.5"	"55.5"	"53.7"	"57.6"	"69.1"	"115.4"	"127.8"	"246.9"	"274.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9BW83"	"Intraflagellar transport protein 27 homolog OS=Homo sapiens OX=9606 GN=IFT27 PE=1 SV=1"	""	""	"13"	"1"	"1"	"1"	"186"	"20.5"	"5.41"	""	"3.53"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytoskeleton;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00071"	"11020"	"ENSG00000100360"	"IFT27"	"hsa:11020; O60897; Q9BW83"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein; Genes related to primary cilium development (based on CRISPR); Ciliopathies; GDNF/RET signaling axis; Alstrom syndrome; Bardet-Biedl syndrome"	"Intraflagellar transport"	"8"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P82675"	"28S ribosomal protein S5, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS5 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"430"	"48.0"	"9.92"	"454.72"	"3.52"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00333, Pf03719"	"64969"	"ENSG00000144029"	"MRPS5"	"hsa:64969; P82675; Q4ZFY5; Q96LJ6; Q9BWI4; Q9BYC4"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"36.4"	"40.8"	"51.1"	"50.8"	"54.9"	"42.0"	"59.9"	"70.9"	"61.7"	"87.3"	"140.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75347"	"Tubulin-specific chaperone A OS=Homo sapiens OX=9606 GN=TBCA PE=1 SV=3"	"0.000"	""	"10"	"1"	"2"	"1"	"108"	"12.8"	"5.29"	"500.47"	"3.52"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02970"	"6902"	"ENSG00000171530"	"TBCA"	"B4DT30; hsa:6902; O75347"	"VEGFA-VEGFR2 signaling"	"Post-chaperonin tubulin folding pathway"	"2"	"0"	"38.5"	"34.4"	"39.2"	"34.4"	"26.7"	"24.4"	"37.0"	"69.7"	"50.7"	"185.6"	"347.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q99714"	"3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3"	""	""	"4"	"1"	"1"	"1"	"261"	"26.9"	"7.78"	""	"3.51"	""	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"plasma membrane;other membranes;mitochondrion;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00106"	"3028"	"ENSG00000072506"	"HSD17B10"	"hsa:3028; Q5H927; Q6IBS9; Q8TCV9; Q96HD5; Q99714"	"Alzheimer's disease and miRNA effects; Valproic acid pathway; Alzheimer's disease"	"Branched-chain amino acid catabolism; tRNA processing in the mitochondrion; tRNA modification in the mitochondrion; rRNA processing in the mitochondrion"	"7"	"0"	"91.8"	"64.0"	"127.2"	"74.8"	"85.8"	"79.0"	"86.4"	"147.0"	"185.6"	"465.9"	"866.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P54132"	"Bloom syndrome protein OS=Homo sapiens OX=9606 GN=BLM PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1417"	"158.9"	"7.49"	"347.71"	"3.51"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf00570, Pf08072, Pf09382, Pf16124, Pf16202, Pf16204"	"641"	"ENSG00000197299"	"BLM"	"hsa:641; P54132; Q52M96"	"Primary ovarian insufficiency"	"Resolution of D-loop Structures through Holliday Junction Intermediates; SUMOylation of DNA damage response and repair proteins; Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; Meiotic recombination; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Processive synthesis on the C-strand of the telomere"	"18"	"0"	"6.0"	"0.0"	"3.8"	"5.0"	"4.4"	"7.3"	"7.9"	"12.8"	"11.2"	"34.5"	"56.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L9L4"	"MOB kinase activator 1B OS=Homo sapiens OX=9606 GN=MOB1B PE=1 SV=3"	"0.000"	""	"5"	"1"	"2"	"1"	"216"	"25.1"	"6.73"	"350.69"	"3.51"	"1"	"1"	"signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf03637"	"92597"	"ENSG00000173542"	"MOB1B"	"B2R8U6; B4DRY3; hsa:92597; Q7L9L4; Q8IY23"	"Pleural mesothelioma"	"Signaling by Hippo"	"2"	"0"	"14.5"	"8.8"	"15.1"	"16.6"	"13.9"	"18.0"	"21.2"	"42.0"	"33.3"	"133.6"	"198.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6D9"	"Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"718"	"83.0"	"5.92"	"383.54"	"3.51"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf05557"	"8379"	"ENSG00000002822"	"MAD1L1"	"B3KR41; hsa:8379; Q13312; Q75MI0; Q86UM4; Q9UNH0; Q9Y6D9"	"Cell cycle; Regulation of sister chromatid separation at the metaphase-anaphase transition; Pleural mesothelioma; CCL18 signaling pathway"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"10"	"0"	"87.3"	"56.2"	"68.0"	"72.6"	"72.3"	"74.8"	"91.3"	"123.7"	"130.2"	"199.6"	"207.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86WR7"	"Proline and serine-rich protein 2 OS=Homo sapiens OX=9606 GN=PROSER2 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"435"	"45.8"	"7.20"	"367.40"	"3.51"	"1"	"1"	""	""	""	"Pf15385"	"254427"	"ENSG00000148426"	"PROSER2"	"D3DRR8; hsa:254427; Q5W0J9; Q5W0K0; Q5W0K1; Q5W0K2; Q6PJC8; Q86WR7; Q8N317"	""	""	"0"	"0"	"11.0"	"8.6"	"10.0"	"10.7"	"8.9"	"8.5"	"13.6"	"31.1"	"25.0"	"126.3"	"40.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q70E73"	"Ras-associated and pleckstrin homology domains-containing protein 1 OS=Homo sapiens OX=9606 GN=RAPH1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1250"	"135.2"	"8.85"	"318.64"	"3.50"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	""	"Pf00169, Pf00788"	"65059"	"ENSG00000173166"	"RAPH1"	"hsa:65059; Q70E73; Q96Q37; Q9C0I2"	""	""	"0"	"0"	"2.5"	"4.9"	"3.9"	"5.6"	"6.9"	"6.6"	"6.8"	"14.0"	"17.3"	"41.3"	"83.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVZ3"	"Adaptin ear-binding coat-associated protein 2 OS=Homo sapiens OX=9606 GN=NECAP2 PE=1 SV=1"	"0.000"	""	"10"	"2"	"3"	"1"	"263"	"28.3"	"8.38"	"624.10"	"3.50"	"2"	"1"	"transport"	"plasma membrane;other membranes"	""	"Pf07933"	"55707"	"ENSG00000157191"	"NECAP2"	"B4DY19; E9PGQ8; hsa:55707; Q5VSU4; Q5VSU5; Q9H7L1; Q9H8L1; Q9NVZ3"	""	"Cargo recognition for clathrin-mediated endocytosis"	"2"	"0"	"15.8"	"11.5"	"21.2"	"13.1"	"14.2"	"22.1"	"33.8"	"55.4"	"72.2"	"80.7"	"87.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P41208"	"Centrin-2 OS=Homo sapiens OX=9606 GN=CETN2 PE=1 SV=1"	"0.000"	""	"8"	"1"	"2"	"1"	"172"	"19.7"	"5.00"	"357.82"	"3.50"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;transport;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf13499"	"1069"	"ENSG00000147400"	"CETN2"	"B2R4T4; hsa:1069; P41208; Q53XW1"	"Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; SUMOylation of DNA damage response and repair proteins; Formation of Incision Complex in GG-NER; DNA Damage Recognition in GG-NER"	"13"	"0"	"66.9"	"35.6"	"70.0"	"55.3"	"55.3"	"69.7"	"110.2"	"204.6"	"181.8"	"363.8"	"506.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IYB7"	"DIS3-like exonuclease 2 OS=Homo sapiens OX=9606 GN=DIS3L2 PE=1 SV=4"	"0.000"	""	"2"	"1"	"2"	"1"	"885"	"99.2"	"6.10"	"355.59"	"3.49"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00773, Pf17216, Pf17849, Pf17877"	"129563"	"ENSG00000144535"	"DIS3L2"	"hsa:129563; Q53S79; Q580W6; Q5XKH0; Q69YG5; Q6AW99; Q7Z4T6; Q8IYB7; Q8N9K9"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6PI98"	"INO80 complex subunit C OS=Homo sapiens OX=9606 GN=INO80C PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"192"	"20.6"	"10.02"	"530.02"	"3.49"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus"	""	"Pf08265"	"125476"	"ENSG00000153391"	"INO80C"	"B4DUI4; E9PCS7; hsa:125476; Q6PI98; Q86WR1; Q8N994"	""	"UCH proteinases; DNA Damage Recognition in GG-NER"	"2"	"0"	"8.6"	"6.7"	"8.5"	"9.9"	"10.0"	"8.1"	"12.1"	"32.0"	"29.5"	"82.8"	"117.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9GZT3"	"SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1"	"0.000"	""	"13"	"1"	"2"	"1"	"109"	"12.3"	"10.24"	"297.73"	"3.48"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;mitochondrion;nucleus;other cell component"	""	"Pf00076"	"81892"	"ENSG00000119705"	"SLIRP"	"hsa:81892; J3KMY7; Q9GZT3"	""	""	"0"	"0"	"29.2"	"15.9"	"23.4"	"23.4"	"21.1"	"25.9"	"33.2"	"53.6"	"52.5"	"103.4"	"109.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UGP8"	"Translocation protein SEC63 homolog OS=Homo sapiens OX=9606 GN=SEC63 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"760"	"87.9"	"5.31"	"475.96"	"3.48"	"1"	"1"	"other metabolic processes;transport;developmental processes"	"other membranes;ER/Golgi"	"transporter activity;other molecular function"	"Pf00226, Pf02889"	"11231"	"ENSG00000025796"	"SEC63"	"hsa:11231; O95380; Q5THN4; Q86VS9; Q8IWL0; Q9NTE0; Q9UGP8"	""	""	"0"	"0"	"3.6"	"6.4"	"10.1"	"4.1"	"3.7"	"8.9"	"8.7"	"35.5"	"28.9"	"179.9"	"317.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBT7"	"Alpha-catulin OS=Homo sapiens OX=9606 GN=CTNNAL1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"734"	"81.8"	"6.64"	"394.61"	"3.48"	"1"	"1"	"cell adhesion;signal transduction"	"plasma membrane;other membranes;cytosol;cytoskeleton"	"cytoskeletal activity;other molecular function"	"Pf01044"	"8727"	"ENSG00000119326"	"CTNNAL1"	"B5BU47; hsa:8727; O76084; Q53FQ2; Q5JTQ7; Q5JTQ8; Q9UBT7; Q9Y401"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q01780"	"Exosome component 10 OS=Homo sapiens OX=9606 GN=EXOSC10 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"885"	"100.8"	"8.46"	"357.90"	"3.48"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00570, Pf01612, Pf08066"	"5394"	"ENSG00000171824"	"EXOSC10"	"B1AKQ0; B1AKQ1; hsa:5394; Q01780; Q15158"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"43.9"	"36.6"	"47.4"	"41.5"	"44.5"	"56.7"	"79.8"	"120.8"	"111.4"	"202.2"	"276.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35222"	"Catenin beta-1 OS=Homo sapiens OX=9606 GN=CTNNB1 PE=1 SV=1"	"0.000"	""	"4"	"3"	"4"	"2"	"781"	"85.4"	"5.86"	"893.39"	"3.47"	"3"	"1"	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00514"	"1499"	"ENSG00000168036"	"CTNNB1"	"A8K1L7; hsa:1499; P35222; Q8NEW9; Q8NI94; Q9H391"	"Androgen receptor signaling pathway; MicroRNAs in cardiomyocyte hypertrophy; Heart development; TNF-related weak inducer of apoptosis (TWEAK) signaling pathway; Alzheimer's disease and miRNA effects; Neural crest differentiation; Arrhythmogenic right ventricular cardiomyopathy; Pathogenic Escherichia coli infection; Corticotropin-releasing hormone signaling pathway; Adipogenesis; Gastric cancer network 2; Brain-derived neurotrophic factor (BDNF) signaling pathway; Primary focal segmental glomerulosclerosis (FSGS); Endoderm differentiation; Ectoderm differentiation; Extracellular vesicle-mediated signaling in recipient cells; Focal adhesion; Ectoderm differentiation; RAC1/PAK1/p38/MMP2 pathway; Wnt signaling pathway; Regulation of Wnt / B-catenin signaling by small molecule compounds; Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; Embryonic stem cell pluripotency pathways; H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity; OSX and miRNAs in tooth development; Wnt signaling pathway and pluripotency; PTF1A related regulatory pathway; Wnt signaling in kidney disease; Endometrial cancer; Chromosomal and microsatellite instability in colorectal cancer ; Epithelial to mesenchymal transition in colorectal cancer; lncRNA in canonical Wnt signaling and colorectal cancer; Breast cancer pathway; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Ciliary landscape; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; Gastrin signaling pathway; Head and neck squamous cell carcinoma; Thyroid hormones production and peripheral downstream signaling effects; IL-18 signaling pathway; Osteoblast differentiation and related diseases; TGF-beta receptor signaling in skeletal dysplasias; Genes controlling nephrogenesis; GDNF/RET signaling axis; Mammalian disorder of sexual development; Influence of laminopathies on Wnt signaling; Overlap between signal transduction pathways contributing to LMNA laminopathies; 1q21.1 copy number variation syndrome; 7q11.23 copy number variation syndrome; Development of ureteric collection system; Pleural mesothelioma; Alzheimer's disease; Urotensin-II-mediated signaling pathway; Markers of kidney cell lineage; TROP2 regulatory signaling; 8p23.1 copy number variation syndrome; A network map of Macrophage-stimulating protein (MSP) signaling; TGF-beta receptor signaling; Sudden infant death syndrome (SIDS) susceptibility pathways; DNA damage response (only ATM dependent)"	"Somitogenesis; Deactivation of the beta-catenin transactivating complex; InlA-mediated entry of Listeria monocytogenes into host cells; RHO GTPases activate IQGAPs; Formation of paraxial mesoderm; Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1); Formation of axial mesoderm; Myogenesis; Transcriptional Regulation by VENTX; Ca2+ pathway; Disassembly of the destruction complex and recruitment of AXIN to the membrane; Beta-catenin phosphorylation cascade; Signaling by GSK3beta mutants; CTNNB1 S33 mutants aren't phosphorylated; CTNNB1 S37 mutants aren't phosphorylated; CTNNB1 S45 mutants aren't phosphorylated; CTNNB1 T41 mutants aren't phosphorylated; Cardiogenesis; Germ layer formation at gastrulation; Formation of definitive endoderm; VEGFR2 mediated vascular permeability; Adherens junctions interactions; Regulation of CDH11 function; Regulation of CDH19 Expression and Function; CDH11 homotypic and heterotypic interactions; Binding of TCF/LEF:CTNNB1 to target gene promoters; RUNX3 regulates WNT signaling; Apoptotic cleavage of cell adhesion  proteins; LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production"	"96"	"1"	"215.9"	"199.5"	"188.8"	"181.3"	"170.5"	"187.3"	"239.4"	"381.9"	"350.9"	"775.8"	"1358.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L0Y3"	"tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"403"	"47.3"	"9.36"	"312.89"	"3.47"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01746"	"54931"	"ENSG00000174173"	"TRMT10C"	"hsa:54931; Q7L0Y3; Q9NRG5; Q9NX54; Q9Y596"	""	"tRNA processing in the mitochondrion; tRNA modification in the mitochondrion; rRNA processing in the mitochondrion"	"3"	"0"	"31.4"	"16.9"	"32.4"	"25.2"	"35.1"	"27.4"	"36.2"	"57.6"	"53.5"	"76.9"	"81.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92556"	"Engulfment and cell motility protein 1 OS=Homo sapiens OX=9606 GN=ELMO1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"727"	"83.8"	"6.28"	"337.90"	"3.46"	"1"	"1"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf04727, Pf11841, Pf16457"	"9844"	"ENSG00000155849"	"ELMO1"	"A4D1X6; hsa:9844; Q29R79; Q6ZTJ0; Q92556; Q96PB0; Q9H0I1"	"Chemokine signaling pathway; CCL18 signaling pathway"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; VEGFA-VEGFR2 Pathway; PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases; Nef and signal transduction"	"7"	"0"	"15.0"	"10.4"	"12.3"	"18.6"	"30.1"	"69.7"	"121.8"	"141.1"	"110.5"	"89.3"	"120.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y5K5"	"Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3"	""	""	"10"	"1"	"1"	"1"	"329"	"37.6"	"5.33"	""	"3.46"	""	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf01088, Pf18031"	"51377"	"ENSG00000116750"	"UCHL5"	"hsa:51377; Q5LJA6; Q5LJA7; Q8TBS4; Q96BJ9; Q9H1W5; Q9P0I3; Q9UQN2; Q9Y5K5"	""	"UCH proteinases; Downregulation of TGF-beta receptor signaling"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96C19"	"EF-hand domain-containing protein D2 OS=Homo sapiens OX=9606 GN=EFHD2 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"240"	"26.7"	"5.20"	"341.27"	"3.46"	"1"	"1"	""	"other membranes"	"other molecular function"	"Pf13499"	"79180"	"ENSG00000142634"	"EFHD2"	"hsa:79180; Q5JYW9; Q96C19"	""	"RHOD GTPase cycle"	"1"	"0"	"29.3"	"20.3"	"32.7"	"28.9"	"28.3"	"35.8"	"38.8"	"70.7"	"67.9"	"166.5"	"245.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14137"	"Ribosome biogenesis protein BOP1 OS=Homo sapiens OX=9606 GN=BOP1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"746"	"83.6"	"6.19"	"291.27"	"3.46"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00400, Pf08145"	"23246"	"ENSG00000261236; ENSG00000285301"	"BOP1"	"hsa:23246; Q14137; Q969Z6; Q96IS8; Q96Q25; Q9BSA7; Q9BVM0"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"29.4"	"37.1"	"35.1"	"34.5"	"32.9"	"41.6"	"35.6"	"64.2"	"61.4"	"119.3"	"154.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14139"	"Ubiquitin conjugation factor E4 A OS=Homo sapiens OX=9606 GN=UBE4A PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1066"	"122.5"	"5.24"	"418.72"	"3.46"	"1"	"1"	"protein metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf04564, Pf10408"	"9354"	"ENSG00000110344"	"UBE4A"	"B0YJB6; hsa:9354; Q14139; Q2M1H0; Q6P5T4; Q7Z639"	""	"Antigen processing: Ubiquitination & Proteasome degradation"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q3V6T2"	"Girdin OS=Homo sapiens OX=9606 GN=CCDC88A PE=1 SV=2"	"0.000"	""	"1"	"3"	"4"	"2"	"1871"	"215.9"	"6.21"	"822.60"	"3.46"	"3"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf19047"	"55704"	"ENSG00000115355"	"CCDC88A"	"A1IGE7; B7ZM78; C9JG83; hsa:55704; Q3V6T2; Q53SF1; Q581G3; Q5HYD0; Q7Z339; Q7Z3C5"	"Mesodermal commitment pathway"	"RND3 GTPase cycle; RND1 GTPase cycle"	"3"	"0"	"65.3"	"41.4"	"49.6"	"55.9"	"50.5"	"53.8"	"80.1"	"304.7"	"263.8"	"720.3"	"748.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92552"	"28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3"	"0.000"	""	"6"	"2"	"3"	"2"	"414"	"47.6"	"6.18"	"785.06"	"3.46"	"2"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf10037"	"23107"	"ENSG00000113048"	"MRPS27"	"B4DRT2; hsa:23107; Q6P1S1; Q92552"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"116.1"	"92.5"	"140.4"	"105.0"	"105.4"	"126.0"	"177.8"	"330.5"	"322.7"	"733.5"	"1048.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2K7"	"Lysine-specific demethylase 2A OS=Homo sapiens OX=9606 GN=KDM2A PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1162"	"132.7"	"7.58"	"571.95"	"3.45"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00646, Pf02008, Pf16866, Pf17811"	"22992"	"ENSG00000173120"	"KDM2A"	"D4QA03; E9PIL6; hsa:22992; I3VM55; Q49A21; Q4G0M3; Q69YY8; Q9BVH5; Q9H7H5; Q9UK66; Q9Y2K7"	""	"HDMs demethylate histones"	"1"	"0"	"20.0"	"12.2"	"14.6"	"11.0"	"12.4"	"16.2"	"12.8"	"19.7"	"23.8"	"56.3"	"46.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"C9JLW8"	"Mapk-regulated corepressor-interacting protein 1 OS=Homo sapiens OX=9606 GN=MCRIP1 PE=1 SV=1"	"0.000"	""	"11"	"1"	"2"	"1"	"97"	"10.9"	"9.41"	"469.26"	"3.45"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	""	"Pf14799"	"348262"	"ENSG00000225663; ENSG00000288213"	"MCRIP1"	"C9JLW8; hsa:348262; Q6ZUL0"	""	""	"0"	"0"	"82.9"	"55.5"	"91.6"	"75.4"	"78.4"	"79.9"	"101.0"	"161.8"	"158.5"	"394.5"	"554.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q7Z745"	"Maestro heat-like repeat-containing protein family member 2B OS=Homo sapiens OX=9606 GN=MROH2B PE=2 SV=3"	""	""	"1"	"1"	"1"	"1"	"1585"	"180.7"	"6.28"	""	"3.44"	""	"1"	"signal transduction;other biological processes"	"cytoskeleton;other cell component"	""	""	"133558"	"ENSG00000171495"	"MROH2B"	"hsa:133558; Q68DM1; Q7Z4U4; Q7Z745; Q8N7X3"	""	""	"0"	"0"	"222.5"	"198.5"	"229.0"	"180.1"	"188.9"	"168.5"	"240.6"	"253.2"	"225.4"	"374.1"	"612.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P32929"	"Cystathionine gamma-lyase OS=Homo sapiens OX=9606 GN=CTH PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"405"	"44.5"	"6.70"	"372.07"	"3.43"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf01053"	"1491"	"ENSG00000116761"	"CTH"	"B4E1R2; E9PDV0; hsa:1491; P32929; Q53FB3; Q53Y79; Q9H4W7; Q9H4W8"	"Selenium micronutrient network; Vitamin B12 metabolism; Folate metabolism; Trans-sulfuration pathway; Trans-sulfuration, one-carbon metabolism and related pathways; Amino acid metabolism; Methionine metabolism leading to sulfur amino acids and related disorders; Ferroptosis"	"Degradation of cysteine and homocysteine; Metabolism of ingested SeMet, Sec, MeSec into H2Se; Cysteine formation from homocysteine"	"11"	"0"	"61.2"	"48.4"	"67.8"	"46.9"	"47.9"	"48.4"	"54.6"	"113.0"	"104.8"	"195.9"	"289.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NC96"	"Adaptin ear-binding coat-associated protein 1 OS=Homo sapiens OX=9606 GN=NECAP1 PE=1 SV=2"	"0.000"	""	"7"	"2"	"3"	"1"	"275"	"29.7"	"6.80"	"608.25"	"3.43"	"2"	"1"	"transport"	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf07933"	"25977"	"ENSG00000089818"	"NECAP1"	"hsa:25977; Q2NL73; Q5XG95; Q6NWY6; Q8N153; Q8NC96; Q8NCB0; Q9BU52; Q9Y407"	""	"Golgi Associated Vesicle Biogenesis; Cargo recognition for clathrin-mediated endocytosis"	"3"	"1"	"101.8"	"75.2"	"101.5"	"84.7"	"100.7"	"333.5"	"696.8"	"1116.6"	"926.7"	"663.8"	"617.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75165"	"DnaJ homolog subfamily C member 13 OS=Homo sapiens OX=9606 GN=DNAJC13 PE=1 SV=5"	"0.000"	""	"1"	"1"	"2"	"1"	"2243"	"254.3"	"6.74"	"449.65"	"3.43"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	""	"Pf00226, Pf14237, Pf19432"	"23317"	"ENSG00000138246"	"DNAJC13"	"hsa:23317; O75165; Q3L0T1; Q6PI82; Q6UJ77; Q6ZSW1; Q6ZUT5; Q86XG3; Q96DC1; Q9BWK9"	""	"Neutrophil degranulation"	"1"	"0"	"17.2"	"17.0"	"22.5"	"16.2"	"21.2"	"23.3"	"29.9"	"37.5"	"40.2"	"88.9"	"115.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13984"	"General transcription factor IIF subunit 2 OS=Homo sapiens OX=9606 GN=GTF2F2 PE=1 SV=2"	"0.000"	""	"5"	"1"	"2"	"1"	"249"	"28.4"	"9.23"	"492.69"	"3.42"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf02270, Pf17683"	"2963"	"ENSG00000188342"	"GTF2F2"	"A6NNS5; hsa:2963; P13984; Q5W0H3"	"Eukaryotic transcription initiation"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; mRNA Splicing - Major Pathway; Viral Messenger RNA Synthesis; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Estrogen-dependent gene expression; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM"	"33"	"0"	"7.0"	"5.6"	"4.3"	"3.3"	"3.8"	"4.3"	"6.3"	"13.2"	"14.5"	"35.2"	"87.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00193"	"Small acidic protein OS=Homo sapiens OX=9606 GN=SMAP PE=1 SV=1"	"0.000"	""	"13"	"2"	"3"	"2"	"183"	"20.3"	"4.72"	"929.50"	"3.42"	"2"	"1"	""	""	""	"Pf15477"	"10944"	"ENSG00000110696"	"SMAP"	"B2RD28; hsa:10944; O00193"	""	""	"0"	"0"	"546.9"	"447.0"	"491.4"	"513.9"	"459.6"	"473.6"	"610.7"	"668.1"	"621.9"	"840.9"	"1025.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96FZ2"	"Abasic site processing protein HMCES OS=Homo sapiens OX=9606 GN=HMCES PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"354"	"40.5"	"8.15"	""	"3.42"	""	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02586"	"56941"	"ENSG00000183624"	"HMCES"	"A6NJR9; hsa:56941; Q96FZ2; Q96G34; Q9NRP3"	""	""	"0"	"0"	"20.4"	"15.5"	"20.9"	"21.7"	"20.8"	"17.7"	"24.5"	"43.2"	"53.4"	"117.9"	"172.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UL40"	"Zinc finger protein 346 OS=Homo sapiens OX=9606 GN=ZNF346 PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"294"	"32.9"	"9.09"	""	"3.42"	""	"1"	""	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf12874"	"23567"	"ENSG00000113761"	"ZNF346"	"B7Z367; hsa:23567; Q68CV9; Q6ZMW1; Q9UL40"	"5q35 copy number variation"	""	"1"	"0"	"88.0"	"59.8"	"101.0"	"71.7"	"82.1"	"76.4"	"99.0"	"195.3"	"152.9"	"342.4"	"447.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6D6"	"Brefeldin A-inhibited guanine nucleotide-exchange protein 1 OS=Homo sapiens OX=9606 GN=ARFGEF1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1849"	"208.6"	"5.85"	"330.80"	"3.42"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf01369, Pf09324, Pf12783, Pf16213, Pf20252"	"10565"	"ENSG00000066777"	"ARFGEF1"	"hsa:10565; Q9NV46; Q9UFV2; Q9UNL0; Q9Y6D6"	""	""	"0"	"0"	"18.6"	"10.8"	"17.3"	"19.5"	"16.8"	"17.6"	"16.1"	"50.7"	"47.8"	"134.8"	"184.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P36915"	"Guanine nucleotide-binding protein-like 1 OS=Homo sapiens OX=9606 GN=GNL1 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"607"	"68.6"	"5.80"	"439.39"	"3.41"	"1"	"1"	"stress response;signal transduction;other biological processes"	"non-structural extracellular"	"other molecular function"	"Pf01926"	"2794"	"ENSG00000204590; ENSG00000206492; ENSG00000226882; ENSG00000228581; ENSG00000229470; ENSG00000232143; ENSG00000235986"	"GNL1"	"B0S838; hsa:2794; P36915; Q96CT5"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51572"	"B-cell receptor-associated protein 31 OS=Homo sapiens OX=9606 GN=BCAP31 PE=1 SV=3"	"0.000"	""	"4"	"1"	"2"	"1"	"246"	"28.0"	"8.44"	"364.61"	"3.41"	"1"	"1"	"cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf05529, Pf18035"	"10134"	"ENSG00000185825"	"BCAP31"	"B3KQ79; D3DWV5; hsa:10134; P51572; Q13836; Q96CF0"	""	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC; RHOA GTPase cycle; Apoptotic cleavage of cellular proteins"	"4"	"0"	"56.4"	"58.6"	"69.6"	"63.5"	"66.4"	"88.3"	"83.5"	"169.1"	"155.9"	"333.6"	"500.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15164"	"Transcription intermediary factor 1-alpha OS=Homo sapiens OX=9606 GN=TRIM24 PE=1 SV=3"	"0.000"	""	"2"	"2"	"3"	"2"	"1050"	"116.8"	"7.11"	"568.70"	"3.41"	"2"	"1"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;kinase activity;other molecular function"	"Pf00439, Pf00628, Pf00643"	"8805"	"ENSG00000122779"	"TRIM24"	"A4D1R7; A4D1R8; hsa:8805; O15164; O95854"	""	"Signaling by BRAF and RAF1 fusions; Signaling by cytosolic FGFR1 fusion mutants; Signaling by FGFR1 in disease"	"3"	"0"	"99.1"	"62.8"	"106.0"	"99.1"	"92.7"	"90.8"	"108.4"	"172.9"	"177.9"	"327.0"	"405.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15446"	"DNA-directed RNA polymerase I subunit RPA34 OS=Homo sapiens OX=9606 GN=CD3EAP PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"510"	"55.0"	"8.51"	"312.34"	"3.41"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;signal transduction"	"cytosol;mitochondrion;nucleus;other cell component"	""	"Pf08208"	"10849"	"ENSG00000117877"	"POLR1G"	"hsa:10849; O15446; Q32N11; Q7Z5U2; Q9UPF6"	"2q13 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"6"	"0"	"15.5"	"15.9"	"13.5"	"17.9"	"13.5"	"20.6"	"24.5"	"56.3"	"54.1"	"67.5"	"88.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07992"	"DNA excision repair protein ERCC-1 OS=Homo sapiens OX=9606 GN=ERCC1 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"297"	"32.5"	"6.25"	"349.52"	"3.41"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00633, Pf03834"	"2067"	"ENSG00000012061"	"ERCC1"	"B2RC01; B3KRR0; hsa:2067; P07992; Q7Z7F5; Q96S40"	"Male infertility; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"HDR through Single Strand Annealing (SSA); Fanconi Anemia Pathway; Dual incision in TC-NER; Formation of Incision Complex in GG-NER; Dual Incision in GG-NER"	"9"	"0"	"11.7"	"15.5"	"5.5"	"6.1"	"6.6"	"10.1"	"7.3"	"20.5"	"16.8"	"42.6"	"59.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22059"	"Oxysterol-binding protein 1 OS=Homo sapiens OX=9606 GN=OSBP PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"807"	"89.4"	"7.30"	"420.44"	"3.40"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf00169, Pf01237"	"5007"	"ENSG00000110048"	"OSBP"	"hsa:5007; P22059; Q6P524"	""	"Sphingolipid de novo biosynthesis; Synthesis of bile acids and bile salts"	"2"	"0"	"3.7"	"0.0"	"2.2"	"0.0"	"4.8"	"5.5"	"3.1"	"13.4"	"17.8"	"73.1"	"145.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13886"	"Krueppel-like factor 9 OS=Homo sapiens OX=9606 GN=KLF9 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"244"	"27.2"	"8.51"	"350.68"	"3.40"	"1"	"1"	"other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00096"	"687"	"ENSG00000119138"	"KLF9"	"B2R943; hsa:687; Q13886; Q16196"	"Exercise-induced circadian regulation; Familial partial lipodystrophy"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14530"	"Thioredoxin domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TXNDC9 PE=1 SV=2"	"0.000"	""	"5"	"1"	"2"	"1"	"226"	"26.5"	"5.88"	"377.90"	"3.39"	"1"	"1"	"cell organization and biogenesis"	"cytosol;cytoskeleton;nucleus;other cell component"	""	"Pf00085"	"10190"	"ENSG00000115514"	"TXNDC9"	"B2R9G8; D3DVI4; hsa:10190; O14530; Q53HG4; Q53RV8; Q6NSF5; Q8TB70; Q9BRU6"	""	""	"0"	"0"	"2.9"	"5.0"	"3.0"	"4.3"	"3.9"	"7.1"	"7.8"	"16.8"	"24.8"	"97.4"	"217.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08865"	"40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4"	"0.000"	""	"4"	"1"	"2"	"1"	"295"	"32.8"	"4.87"	"349.48"	"3.39"	"1"	"1"	"cell adhesion;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;translational apparatus;nucleus;other cell component"	"translation activity;other molecular function"	"Pf00318, Pf16122"	"3921"	"ENSG00000168028"	"RPSA"	"hsa:3921; P08865; P11085; P12030; Q16471; Q6IPD1; Q6IPD2; Q6NSD1; Q6NXQ8; Q86VC0"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"92.9"	"62.4"	"115.8"	"108.4"	"81.9"	"94.7"	"127.8"	"290.9"	"324.1"	"780.7"	"1039.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15545"	"Transcription initiation factor TFIID subunit 7 OS=Homo sapiens OX=9606 GN=TAF7 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"349"	"40.2"	"5.20"	"350.09"	"3.39"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04658"	"6879"	"ENSG00000178913"	"TAF7"	"B2RBV9; hsa:6879; Q13036; Q15545"	"Eukaryotic transcription initiation"	"RNA Polymerase II Pre-transcription Events; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Regulation of TP53 Activity through Phosphorylation"	"10"	"0"	"50.1"	"40.0"	"79.6"	"60.8"	"57.0"	"77.7"	"107.5"	"121.9"	"118.1"	"140.9"	"160.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7RTN6"	"STE20-related kinase adapter protein alpha OS=Homo sapiens OX=9606 GN=STRADA PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"431"	"48.3"	"6.48"	"307.65"	"3.39"	"1"	"1"	"cell cycle OR cell proliferation;transport;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00069"	"92335"	"ENSG00000266173"	"STRADA"	"B4DDE3; B4DW17; hsa:92335; J3KTC9; Q5JPI2; Q7RTN6; Q7Z4K9; Q8NC31; Q8NCF1; Q9H272"	"AMP-activated protein kinase signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway"	"Energy dependent regulation of mTOR by LKB1-AMPK"	"3"	"0"	"3.2"	"0.0"	"2.0"	"3.9"	"4.8"	"0.0"	"4.0"	"38.6"	"39.7"	"72.0"	"62.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WXI9"	"Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1"	"0.000"	""	"4"	"2"	"3"	"2"	"593"	"65.2"	"9.70"	"494.33"	"3.39"	"2"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00320, Pf16563"	"57459"	"ENSG00000143614; ENSG00000261992"	"GATAD2B"	"D3DUZ2; hsa:57459; Q5VUR2; Q7LG68; Q8WXI9; Q9ULS0"	""	"RNA Polymerase I Transcription Initiation; Potential therapeutics for SARS; Regulation of PTEN gene transcription; HDACs deacetylate histones; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of TP53 Activity through Acetylation"	"6"	"0"	"320.5"	"274.8"	"311.1"	"270.7"	"261.0"	"264.3"	"336.0"	"465.4"	"431.7"	"724.2"	"938.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q15813"	"Tubulin-specific chaperone E OS=Homo sapiens OX=9606 GN=TBCE PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"527"	"59.3"	"6.76"	""	"3.39"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01302, Pf14560"	"6905"	"ENSG00000282984; ENSG00000284770; ENSG00000285053"	"TBCE"	"A8K8C2; B7Z3P1; hsa:6905; Q15813"	""	"Post-chaperonin tubulin folding pathway"	"1"	"0"	"4.4"	"2.9"	"2.9"	"3.1"	"4.8"	"2.8"	"4.0"	"20.5"	"26.0"	"141.9"	"380.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q0VD83"	"Apolipoprotein B receptor OS=Homo sapiens OX=9606 GN=APOBR PE=1 SV=3"	""	""	"3"	"1"	"1"	"1"	"1097"	"115.6"	"4.40"	""	"3.39"	""	"1"	"other metabolic processes;transport"	"non-structural extracellular;plasma membrane;other membranes"	"other molecular function"	""	"55911"	"ENSG00000184730"	"APOBR"	"H3BU97; hsa:55911; Q0VD81; Q0VD83; Q8NC15; Q9NPJ9"	""	"VLDL clearance"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H0U9"	"Testis-specific Y-encoded-like protein 1 OS=Homo sapiens OX=9606 GN=TSPYL1 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"437"	"49.2"	"5.45"	"437.95"	"3.39"	"1"	"1"	"cell organization and biogenesis"	"nucleus;other cell component"	"other molecular function"	"Pf00956"	"7259"	"ENSG00000189241"	"TSPYL1"	"hsa:7259; O75885; Q5TFE6; Q9H0U9"	"Sudden infant death syndrome (SIDS) susceptibility pathways"	""	"1"	"0"	"21.8"	"13.6"	"16.6"	"16.8"	"20.3"	"13.7"	"22.3"	"22.0"	"19.1"	"29.9"	"31.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q03164"	"Histone-lysine N-methyltransferase 2A OS=Homo sapiens OX=9606 GN=KMT2A PE=1 SV=5"	"0.000"	""	"0"	"1"	"2"	"1"	"3969"	"431.5"	"9.09"	"291.69"	"3.39"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00628, Pf00856, Pf02008, Pf05964, Pf05965, Pf13771"	"4297"	"ENSG00000118058"	"KMT2A"	"E9PQG7; hsa:4297; Q03164; Q13743; Q13744; Q14845; Q16364; Q59FF2; Q6UBD1; Q9HBJ3; Q9UD94; Q9UMA3"	"Histone modifications"	"RUNX1 regulates transcription of genes involved in differentiation of HSCs; Formation of WDR5-containing histone-modifying complexes; PKMTs methylate histone lysines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Transcriptional regulation of granulopoiesis"	"6"	"0"	"39.7"	"32.9"	"39.0"	"31.1"	"27.2"	"37.5"	"41.2"	"102.0"	"103.8"	"233.2"	"296.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TBZ3"	"WD repeat-containing protein 20 OS=Homo sapiens OX=9606 GN=WDR20 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"569"	"62.9"	"8.00"	"405.07"	"3.39"	"1"	"1"	""	"nucleus"	""	"Pf00400"	"91833"	"ENSG00000140153"	"WDR20"	"B4DN18; E7EUY8; F8W9S4; G3V2F8; G3V5R0; H0YJJ1; hsa:91833; Q86TU2; Q8NCN7; Q8TBZ3; Q8WXX2; Q9UF86"	""	"Ub-specific processing proteases"	"1"	"0"	"36.0"	"20.2"	"38.3"	"29.6"	"33.2"	"32.1"	"43.5"	"64.6"	"71.2"	"140.6"	"150.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q93008"	"Probable ubiquitin carboxyl-terminal hydrolase FAF-X OS=Homo sapiens OX=9606 GN=USP9X PE=1 SV=3"	"0.000"	""	"0"	"1"	"2"	"1"	"2570"	"292.1"	"5.80"	"365.36"	"3.39"	"1"	"1"	"protein metabolism;other metabolic processes"	""	"other molecular function"	"Pf00443, Pf12030"	"100971796; 465582"	"ENSPPAG00000039671; ENSPTRG00000045541"	"USP9X"	"A0A2I3RAB4; A0A2J8JDU7; A0A2R9BVD0; A0A6D2WW26"	""	""	"0"	"0"	"36.1"	"29.8"	"53.0"	"49.2"	"34.1"	"31.3"	"52.9"	"73.8"	"74.6"	"139.3"	"241.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43324"	"Eukaryotic translation elongation factor 1 epsilon-1 OS=Homo sapiens OX=9606 GN=EEF1E1 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"174"	"19.8"	"8.54"	"342.46"	"3.39"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf00043"	"9521"	"ENSG00000124802"	"EEF1E1"	"C9JLK5; hsa:9521; O43324; Q5THS2"	""	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"2"	"0"	"14.1"	"13.0"	"14.6"	"15.5"	"11.7"	"12.6"	"21.2"	"50.5"	"49.4"	"185.4"	"278.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HC62"	"Sentrin-specific protease 2 OS=Homo sapiens OX=9606 GN=SENP2 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"589"	"67.8"	"9.48"	"283.54"	"3.39"	"1"	"1"	"cell-cell signaling;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;nucleus"	"other molecular function"	"Pf02902"	"59343"	"ENSG00000163904"	"SENP2"	"B4DQ42; hsa:59343; Q8IW97; Q96SR2; Q9HC62; Q9P2L5"	"lncRNA in canonical Wnt signaling and colorectal cancer; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Pleural mesothelioma"	"SUMO is proteolytically processed"	"5"	"0"	"62.1"	"64.0"	"72.4"	"83.2"	"78.7"	"75.7"	"92.4"	"133.6"	"119.2"	"194.3"	"230.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P04114"	"Apolipoprotein B-100 OS=Homo sapiens OX=9606 GN=APOB PE=1 SV=2"	"0.000"	""	"0"	"2"	"3"	"1"	"4563"	"515.3"	"7.05"	"587.13"	"3.38"	"2"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;transporter activity;other molecular function"	"Pf01347, Pf06448, Pf09172, Pf12491"	"338"	"ENSG00000084674"	"APOB"	"hsa:338; O00502; P04114; P78479; P78480; P78481; Q13779; Q13785; Q13786; Q13787; Q13788; Q4ZG63; Q53QC8; Q7Z600; Q9UMN0"	"Selenium micronutrient network; Vitamin B12 metabolism; Folate metabolism; Statin inhibition of cholesterol production; Male infertility; Perturbations to host-cell autophagy, induced by SARS-CoV-2 proteins; Familial hyperlipidemia type 2; Cholesterol metabolism; Female steroid hormones in cardiomyocyte energy metabolism; Fatty Acids and Lipoproteins Transport in Hepatocytes; Enterocyte cholesterol metabolism"	"Cell surface interactions at the vascular wall; Scavenging by Class B Receptors; Regulation of TLR by endogenous ligand; Heme signaling; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Retinoid metabolism and transport; Cargo recognition for clathrin-mediated endocytosis; LDL clearance; Chylomicron clearance; Scavenging by Class A Receptors; Chylomicron assembly; Chylomicron remodeling; VLDL assembly; VLDL clearance; Scavenging by Class F Receptors; Scavenging by Class H Receptors; Platelet sensitization by LDL; LDL remodeling"	"31"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"2.6"	"11.5"	"13.0"	"41.7"	"80.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L2H7"	"Eukaryotic translation initiation factor 3 subunit M OS=Homo sapiens OX=9606 GN=EIF3M PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"374"	"42.5"	"5.63"	"370.87"	"3.36"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01399, Pf18005"	"10480"	"ENSG00000149100"	"EIF3M"	"A8K7X4; B4E2Q4; hsa:10480; O60735; Q2F836; Q53HL6; Q7L2H7; Q9BXW1"	""	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition"	"6"	"0"	"18.0"	"15.2"	"23.5"	"17.2"	"20.8"	"17.5"	"21.1"	"45.4"	"47.4"	"106.0"	"324.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y570"	"Protein phosphatase methylesterase 1 OS=Homo sapiens OX=9606 GN=PPME1 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"386"	"42.3"	"5.97"	"391.05"	"3.36"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes"	"nucleus"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf12697"	"51400"	"ENSG00000214517"	"PPME1"	"B3KMU6; B5MEE7; hsa:51400; J3QT22; Q8WYG8; Q9NVT5; Q9UI18; Q9Y570"	""	"Cyclin A/B1/B2 associated events during G2/M transition"	"1"	"0"	"12.6"	"9.8"	"15.2"	"11.4"	"10.6"	"13.5"	"17.9"	"35.1"	"35.6"	"92.4"	"292.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49916"	"DNA ligase 3 OS=Homo sapiens OX=9606 GN=LIG3 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1009"	"112.8"	"9.01"	"345.06"	"3.36"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00645, Pf01068, Pf04675, Pf04679, Pf16759"	"3980"	"ENSG00000005156"	"LIG3"	"E5KLB5; E5KLB6; hsa:3980; P49916; Q16714; Q6NVK3"	"Base excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; 17q12 copy number variation syndrome"	"HDR through MMEJ (alt-NHEJ); Gap-filling DNA repair synthesis and ligation in TC-NER; Gap-filling DNA repair synthesis and ligation in GG-NER; APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway; Resolution of AP sites via the single-nucleotide replacement pathway"	"9"	"0"	"17.1"	"13.6"	"19.9"	"15.0"	"14.8"	"18.4"	"22.6"	"48.7"	"81.0"	"247.8"	"487.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H583"	"HEAT repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=HEATR1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"2144"	"242.2"	"6.54"	"412.16"	"3.36"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity"	"Pf08146, Pf12397"	"55127"	"ENSG00000119285"	"HEATR1"	"hsa:55127; Q5T3Q8; Q6P197; Q9H583; Q9NW23"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"13.8"	"12.3"	"17.2"	"18.3"	"29.8"	"13.7"	"16.7"	"39.5"	"57.4"	"83.8"	"92.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6KC79"	"Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2"	"0.000"	""	"0"	"1"	"2"	"1"	"2804"	"315.9"	"7.91"	"390.66"	"3.36"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf12765, Pf12830"	"25836"	"ENSG00000164190"	"NIPBL"	"hsa:25836; Q6KC79; Q6KCD6; Q6N080; Q6ZT92; Q7Z2E6; Q8N4M5; Q9Y6Y3; Q9Y6Y4"	"Cohesin complex - Cornelia de Lange syndrome; NIPBL role in DNA damage - Cornelia de Lange syndrome"	"Cohesin Loading onto Chromatin"	"3"	"0"	"0.0"	"2.0"	"3.7"	"6.4"	"5.4"	"5.6"	"8.0"	"17.8"	"18.8"	"38.1"	"42.5"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NS86"	"LanC-like protein 2 OS=Homo sapiens OX=9606 GN=LANCL2 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"450"	"50.8"	"7.43"	"313.76"	"3.35"	"1"	"1"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus"	"other molecular function"	"Pf05147"	"55915"	"ENSG00000132434"	"LANCL2"	"B2R8D4; hsa:55915; Q6NSL4; Q8TCQ3; Q9BSR1; Q9NS86"	""	""	"0"	"0"	"23.2"	"14.7"	"18.2"	"21.6"	"17.6"	"14.7"	"29.2"	"73.3"	"92.7"	"304.0"	"443.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6NYC1"	"Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 OS=Homo sapiens OX=9606 GN=JMJD6 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"403"	"46.4"	"8.69"	"306.28"	"3.35"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02373"	"23210"	"ENSG00000070495"	"JMJD6"	"B3KMN8; B4DGX1; hsa:23210; Q6NYC1; Q86VY0; Q8IUM5; Q9Y4E2"	""	"HDMs demethylate histones"	"1"	"0"	"65.1"	"50.4"	"58.6"	"62.6"	"61.0"	"60.3"	"83.7"	"129.1"	"124.7"	"289.9"	"412.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BVQ7"	"Spermatogenesis-associated protein 5-like protein 1 OS=Homo sapiens OX=9606 GN=SPATA5L1 PE=1 SV=2"	"0.000"	""	"3"	"2"	"3"	"2"	"753"	"80.7"	"8.09"	"596.35"	"3.35"	"2"	"1"	"other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf17862"	"79029"	"ENSG00000171763"	"AFG2B"	"C9JHR5; hsa:79029; Q9BVQ7; Q9H8W7; Q9HA41"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96AY3"	"Peptidyl-prolyl cis-trans isomerase FKBP10 OS=Homo sapiens OX=9606 GN=FKBP10 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"582"	"64.2"	"5.62"	"357.62"	"3.34"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes"	"other membranes;mitochondrion;ER/Golgi"	"other molecular function"	"Pf00254, Pf13202"	"60681"	"ENSG00000141756"	"FKBP10"	"hsa:60681; Q7Z3R4; Q96AY3; Q9H3N3; Q9H6J3; Q9H6N5; Q9UF89"	"Type I collagen synthesis in the context of osteogenesis imperfecta"	""	"1"	"0"	"22.7"	"23.5"	"22.6"	"23.6"	"20.7"	"16.5"	"28.8"	"44.1"	"40.5"	"65.6"	"80.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L804"	"Rab11 family-interacting protein 2 OS=Homo sapiens OX=9606 GN=RAB11FIP2 PE=1 SV=1"	"0.000"	""	"6"	"2"	"3"	"2"	"512"	"58.2"	"9.32"	"608.91"	"3.34"	"2"	"1"	"cell-cell signaling;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00168, Pf09457"	"22841"	"ENSG00000107560"	"RAB11FIP2"	"A6NEI4; hsa:22841; Q3I768; Q7L804; Q9Y2F0"	""	"Vasopressin regulates renal water homeostasis via Aquaporins"	"1"	"0"	"37.8"	"20.0"	"44.1"	"45.8"	"44.1"	"71.7"	"88.7"	"105.8"	"100.5"	"195.2"	"233.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IWZ8"	"SURP and G-patch domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SUGP1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"645"	"72.4"	"7.61"	"272.99"	"3.33"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf01585, Pf01805"	"57794"	"ENSG00000105705"	"SUGP1"	"hsa:57794; O60378; Q6P3X9; Q8IWZ8; Q8TCQ4; Q8WWT4; Q8WWT5; Q9NTG3"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"72.0"	"53.4"	"72.4"	"69.3"	"72.0"	"73.1"	"89.7"	"130.4"	"122.5"	"218.0"	"288.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P38398"	"Breast cancer type 1 susceptibility protein OS=Homo sapiens OX=9606 GN=BRCA1 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1863"	"207.6"	"5.41"	""	"3.33"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00097, Pf00533, Pf12820"	"672"	"ENSG00000012048"	"BRCA1"	"E9PFZ0; hsa:672; O15129; P38398; Q1RMC1; Q3LRJ0; Q3LRJ6; Q6IN79; Q7KYU9"	"Androgen receptor signaling pathway; miRNA regulation of DNA damage response; Glioblastoma signaling pathways; Hepatitis C and hepatocellular carcinoma; Pathways affected in adenoid cystic carcinoma; PI3K-Akt signaling pathway; Breast cancer pathway; DNA repair pathways, full network; Pleural mesothelioma; Nucleotide excision repair in xeroderma pigmentosum ; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; Primary ovarian insufficiency; 5q35 copy number variation; DNA damage response"	"Meiotic synapsis; Resolution of D-loop Structures through Holliday Junction Intermediates; Neddylation; KEAP1-NFE2L2 pathway; SUMOylation of DNA damage response and repair proteins; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; TP53 Regulates Transcription of DNA Repair Genes; Regulation of TP53 Activity through Phosphorylation; Transcriptional Regulation by E2F6; Metalloprotease DUBs; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; Meiotic recombination; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Nonhomologous End-Joining (NHEJ); Defective DNA double strand break response due to BRCA1 loss of function; Defective DNA double strand break response due to BARD1 loss of function"	"40"	"0"	"16.6"	"11.0"	"18.6"	"20.3"	"18.1"	"16.5"	"24.3"	"40.4"	"33.9"	"110.2"	"134.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UNM6"	"26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"376"	"42.9"	"5.81"	"487.82"	"3.33"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf01399"	"5719"	"ENSG00000185627"	"PSMD13"	"B3KT15; hsa:5719; O75831; Q53XU2; Q9UNM6; Q9UNV3"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Ciliary landscape; Alzheimer's disease"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"65"	"0"	"18.0"	"10.5"	"18.6"	"20.3"	"19.2"	"13.6"	"17.3"	"32.4"	"34.7"	"94.8"	"141.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15054"	"DNA polymerase delta subunit 3 OS=Homo sapiens OX=9606 GN=POLD3 PE=1 SV=2"	"0.000"	""	"4"	"2"	"3"	"2"	"466"	"51.4"	"9.35"	"505.58"	"3.33"	"2"	"1"	"DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf09507"	"10714"	"ENSG00000077514"	"POLD3"	"B7ZAI6; hsa:10714; Q15054; Q32MZ9; Q32N00"	"Homologous recombination; Retinoblastoma gene in cancer; Pyrimidine metabolism; DNA replication; Base excision repair; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Polymerase switching on the C-strand of the telomere; Polymerase switching; Removal of the Flap Intermediate; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"26"	"0"	"38.8"	"31.3"	"40.7"	"40.3"	"41.3"	"43.8"	"57.5"	"106.3"	"110.4"	"218.2"	"222.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94887"	"FERM, ARHGEF and pleckstrin domain-containing protein 2 OS=Homo sapiens OX=9606 GN=FARP2 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1054"	"119.8"	"8.79"	"289.18"	"3.33"	"1"	"1"	"cell adhesion;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;cytoskeletal activity"	"Pf00169, Pf00373, Pf00621, Pf08736, Pf09379, Pf09380"	"9855"	"ENSG00000006607"	"FARP2"	"B7Z6J8; F5GZ84; hsa:9855; O94887; Q53QM5; Q8WU27; Q9UFE7"	"2q37 copy number variation syndrome; TAR syndrome"	"RAC1 GTPase cycle; SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q07954"	"Prolow-density lipoprotein receptor-related protein 1 OS=Homo sapiens OX=9606 GN=LRP1 PE=1 SV=2"	""	""	"0"	"1"	"1"	"1"	"4544"	"504.3"	"5.39"	""	"3.33"	""	"1"	"other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00057, Pf00058, Pf07645, Pf12662, Pf14670, Pf16472"	"4035"	"ENSG00000123384"	"LRP1"	"hsa:4035; Q07954; Q2PP12; Q86SW0; Q8IVG8"	"Alzheimer's disease and miRNA effects; Regulation of Wnt / B-catenin signaling by small molecule compounds; Statin inhibition of cholesterol production; Familial  hyperlipidemia type 1; Familial hyperlipidemia type 3; Familial hyperlipidemia type 4; Familial hyperlipidemia type 5; Alzheimer's disease; Cholesterol metabolism"	"Scavenging of heme from plasma; Retinoid metabolism and transport"	"11"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P84090"	"Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1"	"0.000"	""	"11"	"1"	"2"	"1"	"104"	"12.3"	"5.92"	"279.12"	"3.32"	"1"	"1"	"cell cycle OR cell proliferation;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf01133"	"2079"	"ENSG00000100632"	"ERH"	"B2R5H2; hsa:2079; P70659; P84090; Q14259"	""	""	"0"	"0"	"44.4"	"38.5"	"40.9"	"36.1"	"43.9"	"37.0"	"56.6"	"108.7"	"101.0"	"331.0"	"613.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NP61"	"ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"516"	"56.9"	"7.36"	"453.89"	"3.32"	"1"	"1"	"cell organization and biogenesis;transport"	"other membranes;cytosol;ER/Golgi"	"enzyme regulator activity;other molecular function"	"Pf01412"	"26286"	"ENSG00000242247"	"ARFGAP3"	"E9PB03; hsa:26286; Q9BSC6; Q9H9J0; Q9NP61; Q9NT10; Q9NUP5; Q9Y4V3; Q9Y4V4"	"Ciliary landscape"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport; CDC42 GTPase cycle; RHOG GTPase cycle"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12846"	"Syntaxin-4 OS=Homo sapiens OX=9606 GN=STX4 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"297"	"34.2"	"6.28"	"305.11"	"3.32"	"1"	"1"	"cell organization and biogenesis;stress response;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00804, Pf05739"	"6810"	"ENSG00000103496"	"STX4"	"A8MXY0; hsa:6810; Q12846; Q15525; Q6FHE8"	"Insulin signaling"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; ER-Phagosome pathway; trans-Golgi Network Vesicle Budding; Disinhibition of SNARE formation; Other interleukin signaling"	"6"	"0"	"4.1"	"2.9"	"5.3"	"2.7"	"3.5"	"4.3"	"5.3"	"12.6"	"7.1"	"32.3"	"43.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q14653"	"Interferon regulatory factor 3 OS=Homo sapiens OX=9606 GN=IRF3 PE=1 SV=1"	""	""	"5"	"1"	"1"	"1"	"427"	"47.2"	"5.34"	""	"3.32"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00605, Pf10401"	"3661"	"ENSG00000126456"	"IRF3"	"A8K7L2; B2RAZ3; hsa:3661; Q14653; Q5FBY1; Q5FBY2; Q5FBY4; Q7Z5G6"	"Apoptosis; TLR4 signaling and tolerance; Toll-like receptor signaling related to MyD88; Novel intracellular components of RIG-I-like receptor pathway; Fibrin complement receptor 3 signaling pathway; White fat cell differentiation; Ebola virus infection in host; Measles virus infection; Cytosolic DNA-sensing pathway; Hepatitis B infection; Type I interferon induction and signaling during SARS-CoV-2 infection; Host-pathogen interaction of human coronaviruses - interferon induction; SARS coronavirus and innate immunity; STING pathway in Kawasaki-like disease and COVID-19; Mitochondrial immune response to SARS-CoV-2; SARS-CoV-2 innate immunity evasion and cell-specific immune response; Antiviral and anti-inflammatory effects of Nrf2 on SARS-CoV-2 pathway; SARS-CoV-2 B.1.1.7 variant antagonises innate immune activation; Urotensin-II-mediated signaling pathway; Induction of autophagy and toll-like receptor signaling pathways by graphene oxide ; Toll-like receptor signaling pathway"	"ISG15 antiviral mechanism; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Activation of IRF3, IRF7 mediated by TBK1, IKBKE; Interferon gamma signaling; Interferon alpha/beta signaling; Negative regulators of DDX58/IFIH1 signaling; TICAM1-dependent activation of IRF3/IRF7; SARS-CoV-1 activates/modulates innate immune responses; TRAF3-dependent IRF activation pathway; TRAF6 mediated IRF7 activation; Regulation of innate immune responses to cytosolic DNA; IRF3-mediated induction of type I IFN; LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production; IRF3 mediated activation of type 1 IFN"	"36"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NXE8"	"Pre-mRNA-splicing factor CWC25 homolog OS=Homo sapiens OX=9606 GN=CWC25 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"425"	"49.6"	"10.18"	"366.45"	"3.32"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf10197, Pf12542"	"54883"	"ENSG00000273559; ENSG00000276761"	"CWC25"	"A0JLM3; hsa:54883; Q68DK5; Q9NXE8"	"17q12 copy number variation syndrome"	"mRNA Splicing - Major Pathway"	"2"	"0"	"15.5"	"12.1"	"17.1"	"19.2"	"19.4"	"16.1"	"29.1"	"39.8"	"34.3"	"68.6"	"66.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q969S3"	"Zinc finger protein 622 OS=Homo sapiens OX=9606 GN=ZNF622 PE=1 SV=1"	"0.000"	""	"6"	"2"	"3"	"2"	"477"	"54.2"	"6.15"	"818.29"	"3.31"	"2"	"1"	"signal transduction;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf12171, Pf12756"	"90441"	"ENSG00000173545"	"ZNF622"	"hsa:90441; Q969S3"	""	""	"0"	"0"	"5.3"	"3.1"	"4.7"	"4.2"	"6.3"	"6.1"	"6.4"	"9.5"	"12.2"	"37.8"	"71.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9BQC3"	"2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 OS=Homo sapiens OX=9606 GN=DPH2 PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"489"	"52.1"	"5.53"	""	"3.30"	""	"1"	"protein metabolism;other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf01866"	"1802"	"ENSG00000132768"	"DPH2"	"A8MVC9; B2RDE3; B4DNI8; hsa:1802; O60623; Q9BQC3"	""	"Synthesis of diphthamide-EEF2"	"1"	"0"	"16.7"	"14.0"	"10.8"	"11.6"	"9.2"	"10.1"	"13.1"	"46.9"	"45.7"	"98.5"	"125.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8IZ69"	"tRNA (uracil-5-)-methyltransferase homolog A OS=Homo sapiens OX=9606 GN=TRMT2A PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"625"	"68.7"	"7.94"	""	"3.30"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol"	"other molecular function"	"Pf05958"	"27037"	"ENSG00000099899"	"TRMT2A"	"D3DX25; hsa:27037; Q32P57; Q8IZ69; Q96ME6; Q9H732"	"22q11.2 copy number variation syndrome"	""	"1"	"0"	"4.3"	"3.1"	"7.8"	"4.8"	"8.2"	"6.4"	"10.1"	"12.6"	"12.8"	"23.6"	"21.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13541"	"Eukaryotic translation initiation factor 4E-binding protein 1 OS=Homo sapiens OX=9606 GN=EIF4EBP1 PE=1 SV=3"	"0.000"	""	"11"	"1"	"2"	"1"	"118"	"12.6"	"5.48"	"241.82"	"3.30"	"1"	"1"	"cell cycle OR cell proliferation;signal transduction;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf05456"	"1978"	"ENSG00000187840"	"EIF4EBP1"	"B2R502; D3DSW8; hsa:1978; Q13541; Q6IBN3"	"Translation factors; AMP-activated protein kinase signaling; Target of rapamycin signaling; Leptin signaling pathway; Follicle stimulating hormone (FSH) signaling pathway; Prolactin signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; Androgen receptor network in prostate cancer; Brain-derived neurotrophic factor (BDNF) signaling pathway; Alpha 6 beta 4 signaling pathway; RAC1/PAK1/p38/MMP2 pathway; BDNF-TrkB signaling; PI3K-AKT-mTOR signaling pathway and therapeutic opportunities in prostate cancer; 4-hydroxytamoxifen, dexamethasone, and retinoic acids regulation of p27 expression; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; EGF/EGFR signaling pathway; Synaptic signaling pathways associated with autism spectrum disorder; Translation inhibitors in chronically activated PDGFRA cells; Gastrin signaling pathway; Head and neck squamous cell carcinoma; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; Pleural mesothelioma; Network map of SARS-CoV-2 signaling pathway; Hypertrophy model; Interferon type I signaling pathways; ErbB signaling pathway"	"mTORC1-mediated signalling; Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S"	"31"	"0"	"41.4"	"31.2"	"46.8"	"49.7"	"47.1"	"41.0"	"55.4"	"102.1"	"92.9"	"246.2"	"298.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NYR9"	"NF-kappa-B inhibitor-interacting Ras-like protein 2 OS=Homo sapiens OX=9606 GN=NKIRAS2 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"191"	"21.5"	"8.05"	"389.28"	"3.30"	"1"	"1"	"stress response;developmental processes;signal transduction;other biological processes"	"other cell component"	"other molecular function"	"Pf00071"	"28511"	"ENSG00000168256"	"NKIRAS2"	"A6NCZ5; B3KNN0; B4DNM3; hsa:28511; Q6PK52; Q96KC7; Q9NSX1; Q9NYR9"	""	"RIP-mediated NFkB activation via ZBP1; TAK1-dependent IKK and NF-kappa-B activation  ; TRAF6 mediated NF-kB activation"	"3"	"0"	"28.2"	"25.5"	"24.9"	"18.2"	"20.2"	"31.7"	"46.0"	"145.7"	"145.4"	"237.7"	"290.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00743"	"Serine/threonine-protein phosphatase 6 catalytic subunit OS=Homo sapiens OX=9606 GN=PPP6C PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"305"	"35.1"	"5.69"	"348.00"	"3.29"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00149"	"5537"	"ENSG00000119414"	"PPP6C"	"B2R5V6; B7Z2W9; B7Z5K9; hsa:5537; O00743; Q5U0A2; Q9UIC9"	""	"Telomere Extension By Telomerase; COPII-mediated vesicle transport"	"2"	"0"	"48.1"	"16.9"	"53.4"	"59.4"	"48.4"	"47.5"	"61.9"	"98.6"	"96.2"	"253.5"	"300.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NWU2"	"Glucose-induced degradation protein 8 homolog OS=Homo sapiens OX=9606 GN=GID8 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"228"	"26.7"	"4.97"	"311.78"	"3.29"	"1"	"1"	"cell-cell signaling;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf08513, Pf10607"	"54994"	"ENSG00000101193"	"GID8"	"E1P5I3; hsa:54994; Q8N5M5; Q9NWU2"	"Ciliary landscape"	""	"1"	"0"	"15.0"	"10.4"	"15.0"	"13.3"	"15.8"	"14.3"	"16.9"	"45.9"	"53.7"	"168.3"	"262.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBK8"	"Methionine synthase reductase OS=Homo sapiens OX=9606 GN=MTRR PE=1 SV=4"	"0.000"	""	"2"	"1"	"2"	"1"	"698"	"77.6"	"6.49"	"419.48"	"3.29"	"1"	"1"	"DNA metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus"	"other molecular function"	"Pf00175, Pf00258, Pf00667"	"4552"	"ENSG00000124275"	"MTRR"	"hsa:4552; O60471; Q32MA9; Q7Z4M8; Q9UBK8"	"Vitamin B12 metabolism; Folate metabolism; One-carbon metabolism; Male infertility"	"Methylation; Cobalamin (Cbl) metabolism; Sulfur amino acid metabolism; Defective MTRR causes HMAE; Defective MTR causes HMAG"	"9"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86U70"	"LIM domain-binding protein 1 OS=Homo sapiens OX=9606 GN=LDB1 PE=1 SV=2"	"0.001"	""	"3"	"1"	"2"	"1"	"411"	"46.5"	"6.96"	"231.91"	"3.29"	"1"	"1"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01803, Pf17916"	"8861"	"ENSG00000198728"	"LDB1"	"B4DUC4; hsa:8861; O75479; O96010; Q1EQX1; Q86U70; Q9UGM4"	""	"RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of expression of SLITs and ROBOs; Expression and translocation of olfactory receptors; Cardiogenesis"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96A35"	"39S ribosomal protein L24, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL24 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"216"	"24.9"	"9.29"	"351.42"	"3.29"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00467, Pf17136"	"79590"	"ENSG00000143314"	"MRPL24"	"D3DVC8; hsa:79590; Q53G65; Q53HT0; Q5SYZ9; Q5SZ00; Q5SZ02; Q96A35; Q96Q70; Q9H7G3"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"26.0"	"15.6"	"26.6"	"28.1"	"30.7"	"33.7"	"42.6"	"68.2"	"63.3"	"141.0"	"168.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y484"	"WD repeat domain phosphoinositide-interacting protein 4 OS=Homo sapiens OX=9606 GN=WDR45 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"360"	"39.8"	"7.14"	"393.85"	"3.29"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;other cell component"	"other molecular function"	"Pf00400"	"11152"	"ENSG00000196998"	"WDR45"	"A6NGH5; B7WPI2; hsa:11152; Q5MNZ5; Q6IBS7; Q6NT94; Q96H03; Q9Y484"	"Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway"	"Macroautophagy"	"2"	"0"	"23.3"	"12.6"	"24.2"	"21.8"	"26.6"	"22.1"	"28.4"	"53.9"	"61.4"	"92.5"	"132.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q70Z53"	"Protein FRA10AC1 OS=Homo sapiens OX=9606 GN=FRA10AC1 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"315"	"37.5"	"8.10"	"367.45"	"3.28"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf09725"	"118924"	"ENSG00000148690"	"FRA10AC1"	"C9JCR4; C9JCR5; C9JMY4; hsa:118924; Q70Z49; Q70Z50; Q70Z51; Q70Z52; Q70Z53; Q8N293; Q8WVH5; Q96JQ8"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13405"	"39S ribosomal protein L49, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL49 PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"166"	"19.2"	"9.45"	"341.32"	"3.28"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf05046"	"740"	"ENSG00000149792"	"MRPL49"	"B2R4G6; hsa:740; Q13405"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"38.9"	"24.2"	"45.2"	"34.5"	"36.7"	"36.9"	"54.0"	"93.7"	"84.3"	"167.9"	"221.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKD1"	"Glucocorticoid modulatory element-binding protein 2 OS=Homo sapiens OX=9606 GN=GMEB2 PE=1 SV=1"	"0.000"	""	"5"	"2"	"3"	"2"	"530"	"56.4"	"5.60"	"557.50"	"3.28"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01342"	"26205"	"ENSG00000101216"	"GMEB2"	"E1P5J3; hsa:26205; Q5TDS0; Q9H431; Q9H4X7; Q9H4X8; Q9UF78; Q9UKD1; Q9ULF1"	""	""	"0"	"0"	"8.1"	"6.9"	"5.9"	"6.6"	"9.0"	"2.7"	"7.2"	"17.7"	"24.0"	"85.3"	"158.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86YT6"	"E3 ubiquitin-protein ligase MIB1 OS=Homo sapiens OX=9606 GN=MIB1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1006"	"110.1"	"6.92"	"307.81"	"3.28"	"1"	"1"	"protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00569, Pf06701, Pf12796, Pf13920, Pf18346"	"57534"	"ENSG00000101752"	"MIB1"	"B0YJ38; hsa:57534; Q2TB37; Q68D01; Q6YI51; Q86YT6; Q8NBY0; Q8TCB5; Q8TCL7; Q9P2M3"	"Genes related to primary cilium development (based on CRISPR)"	"Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Activated NOTCH1 Transmits Signal to the Nucleus; Constitutive Signaling by NOTCH1 HD Domain Mutants; NOTCH2 Activation and Transmission of Signal to the Nucleus; NOTCH3 Activation and Transmission of Signal to the Nucleus"	"7"	"0"	"15.2"	"16.7"	"18.3"	"15.7"	"15.2"	"12.8"	"21.8"	"50.1"	"36.4"	"109.7"	"157.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HBL8"	"NmrA-like family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=NMRAL1 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"299"	"33.3"	"7.52"	"305.97"	"3.27"	"1"	"1"	""	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf05368"	"57407"	"ENSG00000153406; ENSG00000274684"	"NMRAL1"	"hsa:57407; Q9HBL8"	""	"Urea cycle"	"1"	"0"	"36.6"	"33.1"	"38.0"	"34.2"	"29.6"	"32.8"	"44.5"	"102.9"	"108.4"	"246.7"	"259.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75554"	"WW domain-binding protein 4 OS=Homo sapiens OX=9606 GN=WBP4 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"376"	"42.5"	"5.57"	"403.41"	"3.27"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00397, Pf06220"	"11193"	"ENSG00000120688"	"WBP4"	"B7Z4M2; hsa:11193; O75554; Q32P29"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"32.5"	"29.9"	"37.1"	"34.0"	"32.6"	"28.8"	"35.0"	"38.6"	"39.3"	"95.8"	"139.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95568"	"Histidine protein methyltransferase 1 homolog OS=Homo sapiens OX=9606 GN=METTL18 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"372"	"42.1"	"6.76"	"326.72"	"3.27"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf13489"	"92342"	"ENSG00000171806"	"METTL18"	"B2R9T5; hsa:92342; O95568"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23511"	"Nuclear transcription factor Y subunit alpha OS=Homo sapiens OX=9606 GN=NFYA PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"347"	"36.9"	"8.94"	"351.93"	"3.27"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02045"	"4800"	"ENSG00000001167"	"NFYA"	"hsa:4800; P23511; Q8IXU0"	"Sterol regulatory element-binding proteins (SREBP) signaling; Wnt signaling pathway and pluripotency; Sudden infant death syndrome (SIDS) susceptibility pathways"	"PPARA activates gene expression; Activation of gene expression by SREBF (SREBP); FOXO-mediated transcription of cell death genes; ATF4 activates genes in response to endoplasmic reticulum  stress; ATF6 (ATF6-alpha) activates chaperone genes"	"8"	"0"	"274.0"	"199.7"	"241.4"	"230.9"	"216.2"	"229.6"	"324.3"	"586.0"	"604.6"	"1022.9"	"776.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BPX5"	"Actin-related protein 2/3 complex subunit 5-like protein OS=Homo sapiens OX=9606 GN=ARPC5L PE=1 SV=1"	"0.000"	""	"8"	"1"	"2"	"1"	"153"	"16.9"	"6.60"	"402.37"	"3.27"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf04699"	"81873"	"ENSG00000136950"	"ARPC5L"	"hsa:81873; Q7Z523; Q9BPX5"	"Pathogenic Escherichia coli infection; VEGFA-VEGFR2 signaling"	""	"2"	"0"	"98.3"	"65.1"	"98.9"	"80.1"	"82.0"	"91.0"	"105.5"	"221.1"	"247.3"	"500.5"	"637.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62070"	"Ras-related protein R-Ras2 OS=Homo sapiens OX=9606 GN=RRAS2 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"204"	"23.4"	"6.01"	"452.77"	"3.27"	"1"	"1"	"developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi"	"other molecular function"	"Pf00071"	"22800"	"ENSG00000133818"	"RRAS2"	"B2R9Z3; B7Z5Z2; B7Z6C4; B7Z7H6; hsa:22800; P17082; P62070"	"MAPK signaling pathway; Ras signaling; Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells; EGFR tyrosine kinase inhibitor resistance; Regulation of actin cytoskeleton"	"RND1 GTPase cycle"	"6"	"0"	"12.1"	"12.8"	"18.1"	"14.5"	"8.6"	"12.2"	"17.7"	"39.3"	"35.8"	"91.1"	"131.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55060"	"Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"971"	"110.3"	"5.77"	"364.29"	"3.26"	"1"	"1"	"transport"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf03378, Pf03810, Pf08506"	"1434"	"ENSG00000124207"	"CSE1L"	"A3RLL6; B2R5T4; E1P5Y0; F8W904; hsa:1434; O75432; P55060; Q32M40; Q9H5B7; Q9NTS0; Q9UP98; Q9UP99; Q9UPA0"	""	""	"0"	"0"	"15.1"	"12.3"	"23.2"	"15.1"	"21.8"	"17.9"	"22.5"	"53.1"	"56.0"	"160.0"	"301.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O60566"	"Mitotic checkpoint serine/threonine-protein kinase BUB1 beta OS=Homo sapiens OX=9606 GN=BUB1B PE=1 SV=3"	""	""	"2"	"1"	"1"	"1"	"1050"	"119.5"	"5.27"	""	"3.26"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf08311"	"701"	"ENSG00000156970"	"BUB1B"	"B2R6U0; B4DL09; B4DLG3; hsa:701; O60501; O60566; O60627; O60758; O75389; Q59HH6; Q8WV50; Q96KM4"	"Regulation of sister chromatid separation at the metaphase-anaphase transition; 10q22q23 copy number variation"	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of mitotic proteins; APC-Cdc20 mediated degradation of Nek2A"	"12"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6DCA0"	"AMMECR1-like protein OS=Homo sapiens OX=9606 GN=AMMECR1L PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"310"	"34.5"	"8.98"	"398.86"	"3.26"	"1"	"1"	""	""	""	"Pf01871"	"83607"	"ENSG00000144233"	"AMMECR1L"	"B4E276; hsa:83607; Q6DCA0"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5NDL2"	"EGF domain-specific O-linked N-acetylglucosamine transferase OS=Homo sapiens OX=9606 GN=EOGT PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"527"	"62.0"	"7.05"	"340.55"	"3.26"	"1"	"1"	"protein metabolism;other metabolic processes"	"ER/Golgi"	"other molecular function"	"Pf04577"	"285203"	"ENSG00000163378"	"EOGT"	"A8K2U1; B4DFH5; hsa:285203; L7X1M5; Q5NDL2; Q6MZY0; Q6P985; Q6ZTV0"	"Genetic causes of porto-sinusoidal vascular disease"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IYW5"	"E3 ubiquitin-protein ligase RNF168 OS=Homo sapiens OX=9606 GN=RNF168 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"571"	"65.0"	"7.96"	"360.08"	"3.26"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf14447"	"165918"	"ENSG00000163961"	"RNF168"	"hsa:165918; Q8IYW5; Q8NA67; Q96NS4"	"ATM signaling in development and disease ; 3q29 copy number variation syndrome; NIPBL role in DNA damage - Cornelia de Lange syndrome"	"Processing of DNA double-strand break ends; SUMOylation of DNA damage response and repair proteins; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; G2/M DNA damage checkpoint; Nonhomologous End-Joining (NHEJ)"	"8"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P81605"	"Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2"	"0.000"	""	"15"	"2"	"3"	"2"	"110"	"11.3"	"6.54"	"491.27"	"3.26"	"2"	"1"	"protein metabolism;stress response;transport;other biological processes"	"non-structural extracellular;other membranes"	"transporter activity;other molecular function"	"Pf15291"	"117159"	"ENSG00000161634"	"DCD"	"A5JHP2; A5JHP3; hsa:117159; P58461; P81605; Q53YJ2"	""	"Antimicrobial peptides"	"1"	"0"	"91.1"	"238.3"	"156.9"	"300.1"	"179.5"	"243.4"	"356.2"	"315.3"	"334.6"	"560.8"	"576.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62891"	"60S ribosomal protein L39 OS=Homo sapiens OX=9606 GN=RPL39 PE=1 SV=2"	"0.000"	""	"20"	"1"	"2"	"1"	"51"	"6.4"	"12.56"	"378.62"	"3.25"	"1"	"1"	"protein metabolism;other metabolic processes;stress response"	"non-structural extracellular;cytosol;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00832"	"6170"	"ENSG00000198918"	"RPL39"	"hsa:6170; P02404; P39025; P62891; Q9BYF2"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"95.5"	"45.9"	"83.2"	"81.8"	"78.8"	"68.0"	"112.7"	"126.0"	"117.7"	"184.7"	"257.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q04760"	"Lactoylglutathione lyase OS=Homo sapiens OX=9606 GN=GLO1 PE=1 SV=4"	"0.000"	""	"11"	"1"	"2"	"1"	"184"	"20.8"	"5.31"	"368.31"	"3.25"	"1"	"1"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00903"	"2739"	"ENSG00000124767"	"GLO1"	"B2R6P7; B4DDV0; hsa:2739; P78375; Q04760; Q59EL0; Q5TZW3; Q96FC0; Q96J41"	""	"Pyruvate metabolism"	"1"	"0"	"27.8"	"26.4"	"35.9"	"28.9"	"28.5"	"24.3"	"32.1"	"43.4"	"44.3"	"73.0"	"104.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TCF1"	"AN1-type zinc finger protein 1 OS=Homo sapiens OX=9606 GN=ZFAND1 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"268"	"30.8"	"7.39"	"412.43"	"3.25"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"other cell component"	"other molecular function"	"Pf01428"	"79752"	"ENSG00000104231"	"ZFAND1"	"E5RIG0; E5RJ99; hsa:79752; Q658R7; Q6IA32; Q6PGQ6; Q8TCF1; Q9H810"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49848"	"Transcription initiation factor TFIID subunit 6 OS=Homo sapiens OX=9606 GN=TAF6 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"677"	"72.6"	"8.60"	"297.33"	"3.25"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf02969, Pf07571"	"6878"	"ENSG00000106290"	"TAF6"	"A4D2B2; A4D2B3; B4DT11; D6W5U2; hsa:6878; P49848; Q6AI29"	"Eukaryotic transcription initiation"	"RNA Polymerase II Pre-transcription Events; RNA polymerase II transcribes snRNA genes; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Regulation of TP53 Activity through Phosphorylation"	"11"	"0"	"38.5"	"24.7"	"39.7"	"33.8"	"41.9"	"50.5"	"56.4"	"97.4"	"95.4"	"191.4"	"251.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N2Z9"	"Centromere protein S OS=Homo sapiens OX=9606 GN=CENPS PE=1 SV=1"	"0.000"	""	"9"	"1"	"2"	"1"	"138"	"15.9"	"6.05"	"403.56"	"3.25"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf15630"	"100526739; 378708"	"ENSG00000175279"	"CENPS"	"hsa:100526739; hsa:378708; Q8N2Z9; Q8NFE5; Q8NFG5"	"DNA repair pathways, full network"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Fanconi Anemia Pathway; Deposition of new CENPA-containing nucleosomes at the centromere"	"9"	"0"	"40.5"	"28.6"	"50.6"	"34.6"	"42.0"	"41.2"	"53.2"	"152.2"	"146.3"	"436.4"	"588.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49642"	"DNA primase small subunit OS=Homo sapiens OX=9606 GN=PRIM1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"420"	"49.9"	"8.21"	"433.79"	"3.25"	"1"	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf01896"	"5557"	"ENSG00000198056"	"PRIM1"	"hsa:5557; P49642"	"Retinoblastoma gene in cancer; Pyrimidine metabolism; G1 to S cell cycle control; DNA replication"	"Polymerase switching on the C-strand of the telomere; Polymerase switching; Removal of the Flap Intermediate; Activation of the pre-replicative complex; Defective pyroptosis; Inhibition of replication initiation of damaged DNA by RB1/E2F1; Telomere C-strand synthesis initiation; DNA replication initiation"	"13"	"0"	"33.1"	"33.7"	"41.9"	"41.1"	"39.7"	"32.6"	"44.5"	"88.9"	"93.7"	"246.9"	"301.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12824"	"SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 OS=Homo sapiens OX=9606 GN=SMARCB1 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"385"	"44.1"	"6.23"	"386.54"	"3.25"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04855"	"6598"	"ENSG00000099956; ENSG00000275837"	"SMARCB1"	"hsa:6598; O75784; O95474; Q12824; Q17S11; Q38GA1; Q76N08; Q9UBH2"	"Tumor suppressor activity of SMARCB1; Thermogenesis; Modulators of TCR signaling and T cell activation; DYRK1A involvement regarding cell proliferation in brain development; Kleefstra syndrome; 10q11.21q11.23 copy number variation syndrome"	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; RMTs methylate histone arginines"	"8"	"0"	"54.6"	"38.7"	"49.5"	"47.6"	"54.0"	"51.4"	"64.0"	"96.0"	"95.4"	"177.6"	"208.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96MG7"	"Non-structural maintenance of chromosomes element 3 homolog OS=Homo sapiens OX=9606 GN=NSMCE3 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"304"	"34.3"	"9.28"	"420.55"	"3.24"	"1"	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf01454"	"56160"	"ENSG00000185115; ENSG00000282130"	"NSMCE3"	"hsa:56160; Q8IW16; Q8TEI6; Q96MG7; Q9H214"	"15q11q13 copy number variation"	"SUMOylation of DNA damage response and repair proteins"	"2"	"0"	"38.4"	"33.1"	"42.4"	"35.4"	"34.5"	"36.4"	"47.0"	"61.3"	"62.2"	"105.3"	"137.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94880"	"PHD finger protein 14 OS=Homo sapiens OX=9606 GN=PHF14 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"888"	"100.0"	"5.33"	"303.91"	"3.24"	"1"	"1"	""	""	"other molecular function"	"Pf00628, Pf13832"	"463265"	"ENSPTRG00000018935"	"PHF14"	"A0A2J8MED2; A0A6D2XU20; H2RCM0; ptr:463265"	""	""	"0"	"0"	"12.4"	"12.7"	"12.9"	"12.9"	"9.8"	"9.9"	"17.8"	"34.7"	"35.2"	"52.1"	"81.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43665"	"Regulator of G-protein signaling 10 OS=Homo sapiens OX=9606 GN=RGS10 PE=1 SV=3"	"0.000"	""	"6"	"1"	"2"	"1"	"181"	"21.2"	"7.49"	"283.62"	"3.24"	"1"	"1"	"cell-cell signaling;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00615"	"6001"	"ENSG00000148908"	"RGS10"	"A8K408; B1AMR8; hsa:6001; O43665; Q6IAZ6; Q96GN0"	"Mesodermal commitment pathway; Myometrial relaxation and contraction pathways; Calcium regulation in cardiac cells"	"G alpha (i) signalling events"	"4"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"2.6"	"4.5"	"12.0"	"12.4"	"50.9"	"97.8"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O76003"	"Glutaredoxin-3 OS=Homo sapiens OX=9606 GN=GLRX3 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"335"	"37.4"	"5.39"	"366.08"	"3.22"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00085, Pf00462"	"10539"	"ENSG00000108010"	"GLRX3"	"B3KMP7; B3KMQ5; D3DRG2; hsa:10539; O76003; Q5JV01; Q96CE0; Q9P1B0; Q9P1B1"	""	"Iron uptake and transport"	"1"	"0"	"53.0"	"44.9"	"57.9"	"53.3"	"50.0"	"46.2"	"75.0"	"121.0"	"108.1"	"226.9"	"307.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60942"	"mRNA-capping enzyme OS=Homo sapiens OX=9606 GN=RNGTT PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"597"	"68.5"	"8.13"	"307.79"	"3.22"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00782, Pf01331, Pf03919"	"8732"	"ENSG00000111880"	"RNGTT"	"E1P513; E1P514; hsa:8732; O43483; O60257; O60351; O60942; Q5TCW8; Q8WUM8"	"mRNA processing; Ciliary landscape"	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE"	"5"	"0"	"20.5"	"19.2"	"18.3"	"18.1"	"21.7"	"16.5"	"19.4"	"35.8"	"35.8"	"66.6"	"99.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5J1"	"U3 small nucleolar RNA-associated protein 18 homolog OS=Homo sapiens OX=9606 GN=UTP18 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"556"	"62.0"	"8.76"	"465.97"	"3.22"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;nucleus;other cell component"	""	""	"51096"	"ENSG00000011260"	"UTP18"	"hsa:51096; Q9H4N6; Q9Y5J1"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"43.9"	"35.0"	"42.9"	"32.5"	"41.7"	"42.8"	"46.2"	"48.5"	"60.1"	"89.8"	"129.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99436"	"Proteasome subunit beta type-7 OS=Homo sapiens OX=9606 GN=PSMB7 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"277"	"29.9"	"7.68"	"390.56"	"3.21"	"1"	"1"	"protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00227, Pf12465"	"5695"	"ENSG00000136930"	"PSMB7"	"B4E0P1; hsa:5695; Q5TBG6; Q96AG8; Q99436; Q9BWA7"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"ER-Phagosome pathway; Neutrophil degranulation; Ub-specific processing proteases; MAPK6/MAPK4 signaling; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; UCH proteinases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"63"	"0"	"97.8"	"86.0"	"87.3"	"92.3"	"86.2"	"94.2"	"104.8"	"136.7"	"115.4"	"293.8"	"661.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8WUM4"	"Programmed cell death 6-interacting protein OS=Homo sapiens OX=9606 GN=PDCD6IP PE=1 SV=1"	""	""	"1"	"1"	"1"	"1"	"868"	"96.0"	"6.52"	""	"3.21"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"non-structural extracellular;plasma membrane;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf03097, Pf13949"	"10015"	"ENSG00000170248"	"PDCD6IP"	"C5MQH7; E9PFU1; hsa:10015; Q6NUS1; Q8WUM4; Q9BX86; Q9NUN0; Q9P2H2; Q9UKL5"	"Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells"	"Budding and maturation of HIV virion; Regulation of necroptotic cell death; Uptake and function of anthrax toxins"	"5"	"0"	"6.1"	"0.0"	"7.9"	"7.8"	"9.1"	"5.3"	"8.0"	"22.8"	"17.5"	"54.9"	"141.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86UX6"	"Serine/threonine-protein kinase 32C OS=Homo sapiens OX=9606 GN=STK32C PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"486"	"55.0"	"6.61"	"262.89"	"3.21"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction"	""	"kinase activity;other molecular function"	"Pf00069"	"282974"	"ENSG00000165752"	"STK32C"	"hsa:282974; Q5T0Q5; Q86UE1; Q86UX6"	""	""	"0"	"0"	"7.5"	"5.9"	"9.7"	"9.8"	"7.0"	"10.6"	"9.8"	"67.3"	"78.2"	"204.1"	"252.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96Q05"	"Trafficking protein particle complex subunit 9 OS=Homo sapiens OX=9606 GN=TRAPPC9 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1148"	"128.4"	"6.62"	"455.43"	"3.20"	"1"	"1"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf08626"	"83696"	"ENSG00000167632"	"TRAPPC9"	"hsa:83696; Q4VTT3; Q658K7; Q6P149; Q6ZQT3; Q7L5C4; Q86Y21; Q96Q05; Q96SL2; Q9BQA2"	""	"RAB GEFs exchange GTP for GDP on RABs; COPII-mediated vesicle transport"	"2"	"0"	"4.1"	"3.5"	"6.9"	"4.0"	"5.7"	"5.1"	"7.4"	"17.3"	"13.6"	"27.7"	"29.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P17482"	"Homeobox protein Hox-B9 OS=Homo sapiens OX=9606 GN=HOXB9 PE=1 SV=2"	"0.000"	""	"5"	"1"	"2"	"1"	"250"	"28.0"	"8.90"	"340.46"	"3.19"	"1"	"1"	"developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00046, Pf04617"	"3219"	"ENSG00000170689"	"HOXB9"	"B2RDB7; hsa:3219; P17482; Q9H1I1"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P2X3"	"Protein IMPACT OS=Homo sapiens OX=9606 GN=IMPACT PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"320"	"36.5"	"4.97"	"318.99"	"3.19"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"other cell component"	"cytoskeletal activity;translation activity;other molecular function"	"Pf01205, Pf05773"	"55364"	"ENSG00000154059"	"IMPACT"	"A8MXG0; hsa:55364; Q49AM0; Q9H2X4; Q9P2X3"	""	"Response of EIF2AK4 (GCN2) to amino acid deficiency"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62910"	"60S ribosomal protein L32 OS=Homo sapiens OX=9606 GN=RPL32 PE=1 SV=2"	"0.000"	""	"7"	"1"	"2"	"1"	"135"	"15.9"	"11.33"	"265.82"	"3.19"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01655"	"6161"	"ENSG00000144713"	"RPL32"	"B2R4Q3; hsa:6161; P02433; P62910"	"Cytoplasmic ribosomal proteins"	"SRP-dependent cotranslational protein targeting to membrane; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"31.7"	"30.5"	"33.7"	"24.2"	"30.5"	"33.8"	"46.7"	"133.3"	"137.9"	"290.3"	"496.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00303"	"Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"357"	"37.5"	"5.45"	"273.82"	"3.19"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01398, Pf13012"	"8665"	"ENSG00000175390"	"EIF3F"	"A8K0S2; hsa:8665; O00303; Q6IB45; Q8N978"	"Translation factors; VEGFA-VEGFR2 signaling; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"9"	"0"	"9.7"	"7.5"	"7.9"	"8.3"	"5.7"	"6.4"	"8.2"	"17.7"	"25.3"	"44.8"	"162.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z5G4"	"Golgin subfamily A member 7 OS=Homo sapiens OX=9606 GN=GOLGA7 PE=1 SV=2"	"0.000"	""	"8"	"1"	"2"	"1"	"137"	"15.8"	"7.05"	"416.94"	"3.19"	"1"	"1"	"protein metabolism;other metabolic processes;transport;other biological processes"	"non-structural extracellular;other membranes;ER/Golgi;other cell component"	""	"Pf10256"	"51125"	"ENSG00000147533"	"GOLGA7"	"D3DSX9; hsa:51125; J3KQ24; Q7Z5G4; Q96EQ4; Q9P1S0; Q9Y5U7"	""	"Neutrophil degranulation; RAS processing; Maturation of spike protein"	"3"	"0"	"12.2"	"10.0"	"10.1"	"9.6"	"10.3"	"12.7"	"11.1"	"41.4"	"38.6"	"100.8"	"152.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P21912"	"Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHB PE=1 SV=3"	"0.000"	""	"7"	"3"	"4"	"3"	"280"	"31.6"	"8.76"	"818.79"	"3.18"	"3"	"1"	"other metabolic processes"	"plasma membrane;other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf13085, Pf13534"	"6390"	"ENSG00000117118"	"SDHB"	"B2R545; hsa:6390; P21912; Q0QEY7; Q9NQ12"	"Electron transport chain: OXPHOS system in mitochondria; Metabolic reprogramming in colon cancer; Nonalcoholic fatty liver disease; Mitochondrial complex II assembly; TCA cycle (aka Krebs or citric acid cycle)"	"Respiratory electron transport; Citric acid cycle (TCA cycle)"	"7"	"0"	"267.4"	"216.3"	"264.3"	"247.4"	"239.6"	"199.4"	"288.8"	"504.1"	"500.8"	"936.0"	"1162.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75531"	"Barrier-to-autointegration factor OS=Homo sapiens OX=9606 GN=BANF1 PE=1 SV=1"	"0.000"	""	"13"	"1"	"2"	"1"	"89"	"10.1"	"6.09"	"408.60"	"3.18"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02961"	"8815"	"ENSG00000175334"	"BANF1"	"hsa:8815; O60558; O75531; Q6FGG7"	"Envelope proteins and their potential roles in EDMD physiopathology; Familial partial lipodystrophy; Progeria-associated lipodystrophy"	"Vpr-mediated nuclear import of PICs; 2-LTR circle formation; Integration of viral DNA into host genomic DNA; Autointegration results in viral DNA circles; APOBEC3G mediated resistance to HIV-1 infection; Nuclear Envelope Breakdown; Initiation of Nuclear Envelope (NE) Reformation"	"11"	"0"	"78.6"	"77.8"	"102.8"	"87.3"	"80.7"	"68.3"	"102.9"	"145.3"	"144.0"	"204.3"	"287.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q69YN4"	"Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1812"	"201.9"	"5.01"	"403.86"	"3.18"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf15912"	"25962"	"ENSG00000164944"	"VIRMA"	"hsa:25962; Q2M1N0; Q69YN4; Q6AHX9; Q6NT78; Q7Z6C7; Q8IXH4; Q9BTH4; Q9H9C9; Q9NWR3; Q9P2B8; Q9UFW1"	""	""	"0"	"0"	"0.0"	"3.3"	"3.9"	"5.6"	"2.3"	"3.7"	"7.7"	"7.4"	"13.8"	"27.2"	"44.7"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14202"	"Zinc finger MYM-type protein 3 OS=Homo sapiens OX=9606 GN=ZMYM3 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1370"	"152.3"	"6.35"	"340.25"	"3.17"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf06467, Pf12012"	"9203"	"ENSG00000147130"	"ZMYM3"	"D3DVV3; hsa:9203; O15089; Q14202; Q96E26"	"Orexin receptor pathway"	""	"1"	"0"	"87.1"	"91.5"	"75.3"	"65.7"	"72.4"	"56.1"	"94.5"	"169.1"	"176.1"	"388.5"	"563.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92541"	"RNA polymerase-associated protein RTF1 homolog OS=Homo sapiens OX=9606 GN=RTF1 PE=1 SV=4"	"0.000"	""	"2"	"1"	"2"	"1"	"710"	"80.3"	"8.15"	"273.15"	"3.17"	"1"	"1"	"cell-cell signaling;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf03126"	"23168"	"ENSG00000137815"	"RTF1"	"hsa:23168; Q92541; Q96BX6"	"Endoderm differentiation"	"Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events; E3 ubiquitin ligases ubiquitinate target proteins"	"5"	"0"	"20.2"	"14.4"	"17.6"	"16.8"	"10.0"	"19.1"	"17.9"	"32.3"	"26.6"	"78.7"	"125.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6FIF0"	"AN1-type zinc finger protein 6 OS=Homo sapiens OX=9606 GN=ZFAND6 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"208"	"22.5"	"7.20"	"394.07"	"3.17"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"cytosol"	"nucleic acid binding activity;other molecular function"	"Pf01428, Pf01754"	"54469"	"ENSG00000086666"	"ZFAND6"	"D3DW92; D3DW94; hsa:54469; O95792; Q6FIF0; Q9BQF7; Q9GZY3"	""	"Peroxisomal protein import"	"1"	"0"	"36.6"	"22.0"	"41.8"	"39.0"	"34.6"	"36.2"	"45.9"	"245.3"	"244.5"	"643.6"	"707.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H9Q4"	"Non-homologous end-joining factor 1 OS=Homo sapiens OX=9606 GN=NHEJ1 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"299"	"33.3"	"5.97"	"463.52"	"3.17"	"1"	"1"	"DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09302"	"79840"	"ENSG00000187736"	"NHEJ1"	"B8ZZA4; hsa:79840; Q4ZFW7; Q6IA64; Q96JS9; Q9H9Q4"	"Non-homologous end joining; DNA repair pathways, full network"	"Nonhomologous End-Joining (NHEJ)"	"3"	"0"	"23.2"	"21.0"	"28.7"	"22.2"	"29.9"	"27.0"	"36.2"	"91.3"	"95.6"	"155.8"	"171.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q93074"	"Mediator of RNA polymerase II transcription subunit 12 OS=Homo sapiens OX=9606 GN=MED12 PE=1 SV=4"	"0.000"	""	"1"	"1"	"2"	"1"	"2177"	"242.9"	"7.05"	"369.26"	"3.16"	"1"	"1"	"cell-cell signaling;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09497, Pf12144, Pf12145"	"9968"	"ENSG00000184634"	"MED12"	"hsa:9968; O15410; O75557; Q93074; Q9UHV6; Q9UND7"	""	"Transcriptional regulation of white adipocyte differentiation; PPARA activates gene expression; Generic Transcription Pathway"	"3"	"0"	"4.6"	"5.7"	"6.8"	"4.6"	"5.4"	"5.2"	"7.9"	"15.9"	"17.4"	"42.9"	"68.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N0X4"	"Citramalyl-CoA lyase, mitochondrial OS=Homo sapiens OX=9606 GN=CLYBL PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"340"	"37.3"	"8.73"	"329.81"	"3.16"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"mitochondrion"	"other molecular function"	"Pf03328"	"171425"	"ENSG00000125246"	"CLYBL"	"hsa:171425; Q5W0F7; Q8N0X4; Q8TDH8"	""	""	"0"	"0"	"5.3"	"0.0"	"6.6"	"4.0"	"4.7"	"16.3"	"21.5"	"136.7"	"140.6"	"284.0"	"402.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75487"	"Glypican-4 OS=Homo sapiens OX=9606 GN=GPC4 PE=1 SV=4"	"0.000"	""	"3"	"2"	"3"	"2"	"556"	"62.4"	"6.68"	"596.25"	"3.16"	"2"	"1"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;signal transduction;other biological processes"	"extracellular matrix;plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf01153"	"2239"	"ENSG00000076716"	"GPC4"	"B2R6J7; B4E2C0; hsa:2239; O75487; Q6ZMA6; Q96L43; Q9NU08; Q9UJN1; Q9UPD9"	"Wnt signaling"	"A tetrasaccharide linker sequence is required for GAG synthesis; HS-GAG biosynthesis; HS-GAG degradation; Defective B4GALT7 causes EDS, progeroid type; Defective B3GAT3 causes JDSSDHD; Defective EXT2 causes exostoses 2; Defective EXT1 causes exostoses 1, TRPS2 and CHDS; Defective B3GALT6 causes EDSP2 and SEMDJL1; Attachment and Entry; Retinoid metabolism and transport"	"11"	"0"	"168.7"	"141.0"	"138.5"	"153.1"	"163.7"	"154.2"	"211.8"	"289.6"	"262.7"	"637.2"	"949.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60341"	"Lysine-specific histone demethylase 1A OS=Homo sapiens OX=9606 GN=KDM1A PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"852"	"92.8"	"6.52"	"525.12"	"3.15"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01593, Pf04433"	"23028"	"ENSG00000004487"	"KDM1A"	"A8MWP9; hsa:23028; O60341; Q5TH94; Q5TH95; Q86VT7; Q8IXK4; Q8NDP6; Q8TAZ3; Q96AW4"	"Androgen receptor signaling pathway; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; Thermogenesis; Vitamin D-sensitive calcium signaling in depression; Thyroid hormones production and peripheral downstream signaling effects; Neurogenesis regulation in the olfactory epithelium"	"Estrogen-dependent gene expression; Potential therapeutics for SARS; Regulation of PTEN gene transcription; HDACs deacetylate histones; Factors involved in megakaryocyte development and platelet production; HDMs demethylate histones; NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3"	"14"	"0"	"46.8"	"28.5"	"49.7"	"40.7"	"43.7"	"42.0"	"46.0"	"79.0"	"88.6"	"253.9"	"447.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95299"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFA10 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"355"	"40.7"	"8.48"	"261.45"	"3.15"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion;other cell component"	"transporter activity"	"Pf01712"	"4705"	"ENSG00000130414"	"NDUFA10"	"hsa:4705; O95299; Q8WXC9"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; 2q37 copy number variation syndrome; Oxidative phosphorylation"	"Complex I biogenesis"	"6"	"0"	"36.7"	"30.2"	"35.9"	"30.5"	"25.6"	"30.7"	"49.9"	"71.6"	"62.6"	"130.7"	"190.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16851"	"UTP--glucose-1-phosphate uridylyltransferase OS=Homo sapiens OX=9606 GN=UGP2 PE=1 SV=5"	"0.000"	""	"3"	"1"	"2"	"1"	"508"	"56.9"	"8.15"	"242.80"	"3.15"	"1"	"1"	"other metabolic processes;developmental processes"	"cytosol;other cell component"	"other molecular function"	"Pf01704"	"7360"	"ENSG00000169764"	"UGP2"	"hsa:7360; Q07131; Q0P6K2; Q16851; Q86Y81; Q9BU15"	"Exercise-induced circadian regulation; Glycogen synthesis and degradation; Glucuronidation"	"Glycogen synthesis; Formation of the active cofactor, UDP-glucuronate"	"5"	"0"	"35.7"	"36.2"	"42.3"	"40.9"	"39.3"	"43.1"	"45.3"	"62.1"	"56.6"	"97.9"	"149.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51812"	"Ribosomal protein S6 kinase alpha-3 OS=Homo sapiens OX=9606 GN=RPS6KA3 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"740"	"83.7"	"6.89"	"450.16"	"3.15"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069, Pf00433"	"6197"	"ENSG00000177189"	"RPS6KA3"	"B2R9V4; hsa:6197; P51812; Q4VAP3; Q59H26; Q5JPK8; Q7Z3Z7"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; Kit receptor signaling pathway; MAPK signaling pathway; Angiopoietin-like protein 8 regulatory pathway; Thermogenesis; EGF/EGFR signaling pathway; Cytoplasmic ribosomal proteins; Insulin signaling; Host-pathogen interaction of human coronaviruses - MAPK signaling; Pleural mesothelioma; A network map of Macrophage-stimulating protein (MSP) signaling"	"Senescence-Associated Secretory Phenotype (SASP); Recycling pathway of L1; RSK activation; ERK/MAPK targets; CREB phosphorylation; Gastrin-CREB signalling pathway via PKC and MAPK"	"18"	"0"	"6.2"	"9.1"	"9.3"	"11.0"	"9.2"	"7.5"	"13.3"	"27.2"	"34.6"	"78.0"	"72.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95619"	"YEATS domain-containing protein 4 OS=Homo sapiens OX=9606 GN=YEATS4 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"227"	"26.5"	"8.41"	"389.90"	"3.15"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"other membranes;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03366"	"8089"	"ENSG00000127337"	"YEATS4"	"hsa:8089; O95619; Q9NQD0"	""	"HATs acetylate histones; Activation of the TFAP2 (AP-2) family of transcription factors"	"2"	"0"	"65.8"	"40.8"	"73.1"	"65.8"	"68.2"	"63.6"	"90.0"	"157.2"	"166.7"	"430.1"	"590.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9GZZ1"	"N-alpha-acetyltransferase 50 OS=Homo sapiens OX=9606 GN=NAA50 PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"169"	"19.4"	"8.81"	"273.23"	"3.15"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00583"	"80218"	"ENSG00000121579"	"NAA50"	"D3DN74; hsa:80218; Q68DQ1; Q9GZZ1"	"Metapathway biotransformation Phase I and II"	""	"1"	"0"	"20.1"	"19.8"	"25.8"	"21.3"	"27.2"	"27.7"	"26.2"	"65.9"	"72.3"	"125.5"	"121.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BQ69"	"ADP-ribose glycohydrolase MACROD1 OS=Homo sapiens OX=9606 GN=MACROD1 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"325"	"35.5"	"9.51"	"421.35"	"3.15"	"1"	"1"	"protein metabolism;other metabolic processes;stress response"	"nucleus"	"other molecular function"	"Pf01661"	"28992"	"ENSG00000133315"	"MACROD1"	"hsa:28992; Q9BQ69; Q9UH96"	""	""	"0"	"0"	"35.5"	"29.4"	"37.9"	"33.5"	"41.5"	"39.0"	"59.2"	"177.3"	"201.6"	"411.8"	"461.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96SI9"	"Spermatid perinuclear RNA-binding protein OS=Homo sapiens OX=9606 GN=STRBP PE=1 SV=1"	"0.000"	""	"4"	"2"	"3"	"2"	"672"	"73.6"	"8.72"	"802.90"	"3.15"	"2"	"1"	"other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity"	"Pf00035, Pf07528"	"55342"	"ENSG00000165209"	"STRBP"	"hsa:55342; Q32NB9; Q96SI9; Q9BUE1; Q9BXG4; Q9H0B4; Q9H7V1; Q9NUK4"	""	""	"0"	"0"	"95.6"	"71.5"	"103.8"	"98.7"	"91.8"	"94.7"	"120.8"	"183.9"	"178.1"	"360.4"	"489.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5PSV4"	"Breast cancer metastasis-suppressor 1-like protein OS=Homo sapiens OX=9606 GN=BRMS1L PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"323"	"37.6"	"5.15"	"319.09"	"3.14"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf08598"	"84312"	"ENSG00000100916"	"BRMS1L"	"A6NFW5; A6NH45; B2RD65; hsa:84312; Q5PSV4; Q9BRI4"	""	""	"0"	"0"	"9.4"	"6.8"	"10.6"	"9.2"	"9.9"	"10.0"	"17.5"	"36.0"	"38.8"	"67.7"	"92.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15008"	"26S proteasome non-ATPase regulatory subunit 6 OS=Homo sapiens OX=9606 GN=PSMD6 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"389"	"45.5"	"5.62"	"387.79"	"3.14"	"1"	"1"	"protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	""	"Pf01399, Pf10602"	"9861"	"ENSG00000163636"	"PSMD6"	"A8K2E0; E9PHI9; hsa:9861; Q15008; Q6UV22"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"AUF1 (hnRNP D0) binds and destabilizes mRNA; Regulation of expression of SLITs and ROBOs; Neutrophil degranulation; ABC-family proteins mediated transport; Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"64"	"0"	"100.7"	"60.0"	"118.0"	"100.5"	"102.8"	"102.1"	"134.5"	"339.6"	"338.5"	"810.0"	"1233.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WX93"	"Palladin OS=Homo sapiens OX=9606 GN=PALLD PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1383"	"150.5"	"7.09"	"282.60"	"3.13"	"1"	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf07679"	"23022"	"ENSG00000129116"	"PALLD"	"B3KTG2; B5MD56; B7ZMM5; hsa:23022; Q7L3E0; Q7Z3W0; Q86WE8; Q8N1M2; Q8WX93; Q9UGA0; Q9UQF5; Q9Y2J6; Q9Y3E9"	""	""	"0"	"0"	"17.4"	"10.3"	"26.7"	"15.6"	"20.8"	"17.2"	"22.5"	"51.9"	"55.9"	"173.5"	"206.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14744"	"Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4"	"0.000"	""	"2"	"1"	"2"	"1"	"637"	"72.6"	"6.29"	"271.22"	"3.13"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05185, Pf17285, Pf17286"	"10419"	"ENSG00000100462"	"PRMT5"	"A8MTP3; A8MZ91; B4DX49; B4DY30; B5BU10; D3DS33; E2QRE7; hsa:10419; O14744; Q6IBR1; Q9UKH1"	"Transcription co-factors SKI and SKIL protein partners; Nitric oxide metabolism in cystic fibrosis"	"snRNP Assembly; RMTs methylate histone arginines; Regulation of TP53 Activity through Methylation"	"5"	"0"	"22.7"	"19.5"	"24.4"	"19.1"	"22.8"	"19.9"	"32.7"	"56.8"	"56.0"	"134.9"	"215.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P1X6"	"UPF0598 protein C8orf82 OS=Homo sapiens OX=9606 GN=C8orf82 PE=1 SV=2"	"0.000"	""	"5"	"1"	"2"	"1"	"216"	"23.9"	"9.14"	"364.40"	"3.13"	"1"	"1"	""	""	""	"Pf14956"	"414919"	"ENSG00000213563"	"C8orf82"	"hsa:414919; Q6GMR2; Q6P1X6; Q6P2Q7"	""	""	"0"	"0"	"11.0"	"5.1"	"17.6"	"12.8"	"8.7"	"8.5"	"15.9"	"48.6"	"49.8"	"183.1"	"271.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95373"	"Importin-7 OS=Homo sapiens OX=9606 GN=IPO7 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1038"	"119.4"	"4.82"	"275.17"	"3.13"	"1"	"1"	"stress response;transport;other biological processes"	"cytosol;nucleus"	"enzyme regulator activity;other molecular function"	"Pf03810, Pf08506"	"10527"	"ENSG00000205339"	"IPO7"	"A6NNM5; B2R786; hsa:10527; O95373; Q1RMF7; Q9H177; Q9NTE3"	""	""	"0"	"0"	"4.3"	"3.0"	"2.0"	"5.3"	"5.0"	"4.8"	"4.1"	"10.6"	"19.9"	"77.7"	"118.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NZ56"	"Formin-2 OS=Homo sapiens OX=9606 GN=FMN2 PE=1 SV=4"	""	""	"1"	"1"	"1"	"1"	"1722"	"180.0"	"5.47"	""	"3.13"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity"	"Pf02181"	"56776"	"ENSG00000155816"	"FMN2"	"B0QZA7; B4DP05; hsa:56776; Q59GF6; Q5VU37; Q9NZ55; Q9NZ56"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00584"	"Ribonuclease T2 OS=Homo sapiens OX=9606 GN=RNASET2 PE=1 SV=2"	"0.000"	""	"6"	"1"	"2"	"1"	"256"	"29.5"	"7.08"	"423.62"	"3.13"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;stress response"	"non-structural extracellular;mitochondrion;ER/Golgi;other cytoplasmic organelle"	"nucleic acid binding activity;other molecular function"	"Pf00445"	"8635"	"ENSG00000026297"	"RNASET2"	"B2RDA7; E1P5C3; hsa:8635; O00584; Q5T8Q0; Q8TCU2; Q9BZ46; Q9BZ47"	""	"Neutrophil degranulation"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63173"	"60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2"	"0.000"	""	"23"	"2"	"3"	"1"	"70"	"8.2"	"10.10"	"715.98"	"3.13"	"2"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01781"	"6169"	"ENSG00000172809"	"RPL38"	"B2R5A8; hsa:6169; P23411; P63173"	"Mesodermal commitment pathway; Mesodermal commitment pathway; Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"16"	"0"	"104.8"	"79.7"	"103.8"	"102.5"	"84.4"	"100.7"	"112.3"	"176.7"	"189.0"	"318.9"	"360.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9BTC8"	"Metastasis-associated protein MTA3 OS=Homo sapiens OX=9606 GN=MTA3 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"594"	"67.5"	"8.57"	""	"3.12"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00249, Pf00320, Pf01426, Pf01448, Pf17226"	"57504"	"ENSG00000057935"	"MTA3"	"hsa:57504; Q9BTC8; Q9NSP2; Q9ULF4"	"Pre-implantation embryo; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"Regulation of PTEN gene transcription; HDACs deacetylate histones; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Potential therapeutics for SARS; RNA Polymerase I Transcription Initiation"	"7"	"0"	"9.9"	"11.5"	"15.5"	"14.4"	"7.8"	"7.2"	"18.3"	"30.3"	"29.9"	"67.5"	"84.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q01814"	"Plasma membrane calcium-transporting ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2B2 PE=1 SV=2"	"0.000"	""	"1"	"2"	"3"	"2"	"1243"	"136.8"	"5.91"	"679.01"	"3.11"	"2"	"1"	"transport;developmental processes;other biological processes"	"plasma membrane;other membranes;other cell component"	"signal transduction activity or receptor binding;transporter activity;other molecular function"	"Pf00122, Pf00689, Pf00690, Pf08282, Pf12424, Pf13246"	"491"	"ENSG00000157087"	"ATP2B2"	"hsa:491; O00766; Q01814; Q12994; Q16818"	"Vitamin D-sensitive calcium signaling in depression; PKC-gamma calcium signaling pathway in ataxia; Calcium regulation in cardiac cells"	"Ion homeostasis; Ion transport by P-type ATPases; Reduction of cytosolic Ca++ levels"	"6"	"0"	"45.2"	"45.6"	"50.0"	"55.8"	"48.8"	"46.1"	"61.4"	"167.0"	"195.7"	"618.0"	"782.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60447"	"Ecotropic viral integration site 5 protein homolog OS=Homo sapiens OX=9606 GN=EVI5 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"810"	"92.9"	"6.10"	"421.54"	"3.11"	"1"	"1"	"cell cycle OR cell proliferation;transport;other biological processes"	"cytosol;cytoskeleton;nucleus"	"enzyme regulator activity;other molecular function"	"Pf00566"	"7813"	"ENSG00000067208"	"EVI5"	"A6NKX8; B9A6J0; hsa:7813; O60447; Q9H1Y9"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25788"	"Proteasome subunit alpha type-3 OS=Homo sapiens OX=9606 GN=PSMA3 PE=1 SV=2"	"0.000"	""	"5"	"1"	"2"	"1"	"255"	"28.4"	"5.33"	"358.77"	"3.11"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00227, Pf10584"	"5684"	"ENSG00000100567"	"PSMA3"	"B2RCK6; hsa:5684; P25788; Q86U83; Q8N1D8; Q9BS70"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Activation of NF-kappaB in B cells; ER-Phagosome pathway; Dectin-1 mediated noncanonical NF-kB signaling; NIK-->noncanonical NF-kB signaling; Interleukin-1 signaling; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Antigen processing: Ubiquitination & Proteasome degradation; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; KEAP1-NFE2L2 pathway; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Cross-presentation of soluble exogenous antigens (endosomes); Regulation of ornithine decarboxylase (ODC); Somitogenesis"	"62"	"0"	"94.2"	"57.3"	"120.3"	"114.3"	"119.6"	"100.8"	"120.6"	"154.3"	"172.3"	"215.4"	"375.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86YP4"	"Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"633"	"68.0"	"9.94"	"403.61"	"3.11"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00320, Pf16563"	"54815"	"ENSG00000167491"	"GATAD2A"	"B5MC40; hsa:54815; Q7L3J2; Q86YP4; Q96F28; Q9NPU2; Q9NXS1"	""	"Potential therapeutics for SARS; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of PTEN gene transcription; HDACs deacetylate histones; RNA Polymerase I Transcription Initiation; Regulation of TP53 Activity through Acetylation"	"6"	"0"	"54.2"	"47.4"	"37.7"	"35.5"	"37.0"	"39.6"	"50.5"	"62.3"	"56.7"	"168.4"	"260.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BUK6"	"Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"570"	"61.8"	"6.11"	"282.16"	"3.10"	"1"	"1"	"cell organization and biogenesis"	"other membranes;cytosol;mitochondrion;other cell component"	""	"Pf10644, Pf14881"	"55154"	"ENSG00000125459"	"MSTO1"	"hsa:55154; Q53GR8; Q5CZ69; Q5T717; Q68CT6; Q7LBZ8; Q7Z3M7; Q7Z558; Q8TE05; Q9BUK6; Q9NQX2; Q9NVU4"	""	""	"0"	"0"	"11.9"	"5.1"	"9.2"	"9.0"	"8.1"	"9.1"	"14.2"	"24.2"	"22.3"	"50.3"	"70.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P20585"	"DNA mismatch repair protein Msh3 OS=Homo sapiens OX=9606 GN=MSH3 PE=1 SV=4"	"0.000"	""	"3"	"3"	"4"	"3"	"1137"	"127.3"	"8.02"	"1188.32"	"3.10"	"3"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00488, Pf01624, Pf05188, Pf05192"	"4437"	"ENSG00000113318"	"MSH3"	"A1L480; A1L482; A6NMM6; hsa:4437; P20585; Q6PJT5; Q86UQ6; Q92867"	"Chromosomal and microsatellite instability in colorectal cancer ; DNA repair pathways, full network"	"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta); Defective Mismatch Repair Associated With MSH3; Defective Mismatch Repair Associated With MSH2"	"5"	"0"	"141.1"	"117.4"	"161.9"	"135.6"	"143.6"	"159.7"	"186.1"	"249.2"	"251.4"	"345.4"	"447.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L2E3"	"ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1"	"0.000"	""	"2"	"2"	"4"	"2"	"1194"	"133.9"	"8.78"	"849.84"	"3.10"	"2"	"1"	"cell organization and biogenesis;developmental processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"22907"	"ENSG00000132153"	"DHX30"	"A8K5F1; hsa:22907; O94965; Q7L2E3; Q7Z753; Q96CH4; Q9NUQ0"	""	""	"0"	"0"	"51.5"	"27.5"	"50.1"	"49.0"	"43.6"	"39.1"	"56.5"	"86.6"	"91.1"	"162.7"	"200.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5FBB7"	"Shugoshin 1 OS=Homo sapiens OX=9606 GN=SGO1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"561"	"64.2"	"9.16"	"409.02"	"3.10"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf07557, Pf07558"	"151648"	"ENSG00000129810"	"SGO1"	"hsa:151648; Q588H5; Q5FBB4; Q5FBB5; Q5FBB6; Q5FBB7; Q5FBB8; Q8N579; Q8WVL0; Q9BVA8; Q9H275"	"Cohesin complex - Cornelia de Lange syndrome"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"7"	"0"	"5.8"	"10.3"	"11.5"	"9.2"	"9.3"	"4.7"	"8.0"	"19.1"	"16.8"	"41.1"	"54.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95721"	"Synaptosomal-associated protein 29 OS=Homo sapiens OX=9606 GN=SNAP29 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"258"	"29.0"	"5.81"	"288.07"	"3.10"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	""	"9342"	"ENSG00000099940"	"SNAP29"	"hsa:9342; O95721"	"Ciliary landscape; 22q11.2 copy number variation syndrome"	"Neutrophil degranulation; Intra-Golgi traffic"	"4"	"0"	"26.4"	"16.8"	"20.6"	"19.5"	"17.6"	"19.0"	"27.2"	"45.2"	"36.2"	"67.4"	"90.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A3KN83"	"Protein strawberry notch homolog 1 OS=Homo sapiens OX=9606 GN=SBNO1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1393"	"154.2"	"7.88"	"265.60"	"3.09"	"1"	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf13871, Pf13872"	"55206"	"ENSG00000139697"	"SBNO1"	"A3KN83; hsa:55206; Q05C06; Q3ZTS3; Q9H3T8; Q9NVB2"	""	""	"0"	"0"	"0.0"	"0.0"	"2.9"	"5.0"	"0.0"	"4.9"	"2.6"	"11.4"	"9.6"	"49.8"	"79.8"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9C0B0"	"RING finger protein unkempt homolog OS=Homo sapiens OX=9606 GN=UNK PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"810"	"88.0"	"6.86"	"322.87"	"3.09"	"1"	"1"	"developmental processes;other biological processes"	"other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00642, Pf18384"	"85451"	"ENSG00000132478"	"UNK"	"hsa:85451; Q9C0B0"	""	""	"0"	"0"	"14.1"	"15.0"	"14.7"	"14.5"	"14.2"	"14.1"	"19.9"	"27.1"	"24.8"	"47.4"	"61.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3U8"	"60S ribosomal protein L36 OS=Homo sapiens OX=9606 GN=RPL36 PE=1 SV=3"	"0.000"	""	"15"	"2"	"3"	"2"	"105"	"12.2"	"11.59"	"603.26"	"3.09"	"2"	"1"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus"	"other molecular function"	"Pf01158"	"25873"	"ENSG00000130255"	"RPL36"	"B2R4Y1; D6W634; hsa:25873; Q6FIG1; Q9UQF6; Q9Y3U8"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"132.6"	"103.7"	"137.8"	"109.4"	"112.3"	"113.6"	"177.9"	"312.3"	"317.8"	"865.5"	"1425.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75616"	"GTPase Era, mitochondrial OS=Homo sapiens OX=9606 GN=ERAL1 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"437"	"48.3"	"8.84"	"478.21"	"3.09"	"1"	"1"	"cell organization and biogenesis"	"other membranes;cytosol;mitochondrion"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf01926"	"26284"	"ENSG00000132591"	"ERAL1"	"B3KN21; C9JEC6; hsa:26284; O75616; O75617; Q8WUY4; Q96LE2; Q96TC0"	"Primary ovarian insufficiency"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"4"	"0"	"62.8"	"37.7"	"60.1"	"53.7"	"66.5"	"55.0"	"68.4"	"96.3"	"84.4"	"102.4"	"146.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9ULH0"	"Kinase D-interacting substrate of 220 kDa OS=Homo sapiens OX=9606 GN=KIDINS220 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1771"	"196.4"	"6.62"	"384.87"	"3.09"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf07693, Pf12796"	"57498"	"ENSG00000134313"	"KIDINS220"	"A1L4N4; hsa:57498; Q4VC08; Q6MZU2; Q9H889; Q9H9E4; Q9NT37; Q9UF42; Q9ULH0"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; Neural crest cell migration in cancer"	"RND1 GTPase cycle; RND2 GTPase cycle; ARMS-mediated activation"	"5"	"0"	"4.7"	"0.0"	"8.6"	"5.4"	"4.4"	"6.3"	"5.2"	"13.7"	"21.4"	"54.9"	"50.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14739"	"Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2"	"0.000"	""	"3"	"2"	"3"	"2"	"615"	"70.7"	"9.36"	"651.82"	"3.09"	"2"	"1"	"other metabolic processes;other biological processes"	"other membranes;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01222, Pf09465"	"3930"	"ENSG00000143815"	"LBR"	"B2R5P3; hsa:3930; Q14739; Q14740; Q53GU7; Q59FE6"	"Gastric cancer network 2; ATM signaling in development and disease ; Envelope proteins and their potential roles in EDMD physiopathology; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Cholesterol biosynthesis with skeletal dysplasias; Cholesterol synthesis disorders; Cholesterol metabolism; Enterocyte cholesterol metabolism"	"RHOC GTPase cycle; RHOA GTPase cycle; RHOD GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; Regulation of MECP2 expression and activity; Initiation of Nuclear Envelope (NE) Reformation; Cholesterol biosynthesis"	"19"	"0"	"295.8"	"203.2"	"295.6"	"286.1"	"254.3"	"272.9"	"313.0"	"611.4"	"594.2"	"1177.9"	"1476.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IYH5"	"ZZ-type zinc finger-containing protein 3 OS=Homo sapiens OX=9606 GN=ZZZ3 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"903"	"102.0"	"5.69"	"320.71"	"3.09"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00249, Pf00569"	"26009"	"ENSG00000036549"	"ZZZ3"	"B7WPC6; hsa:26009; Q6N004; Q6N070; Q8IYH5; Q8IYP0; Q8IYR1; Q8TEK4; Q9Y4U0"	""	"Formation of WDR5-containing histone-modifying complexes; HATs acetylate histones"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UJX2"	"Cell division cycle protein 23 homolog OS=Homo sapiens OX=9606 GN=CDC23 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"597"	"68.8"	"7.02"	"333.44"	"3.09"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf04049"	"8697"	"ENSG00000094880"	"CDC23"	"A8K6E5; B4E3A2; B7WP05; D3DQB7; hsa:8697; O75433; Q53FN2; Q9BS73; Q9UJX2"	"Cell cycle"	"Separation of Sister Chromatids; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Inactivation of APC/C via direct inhibition of the APC/C complex; APC-Cdc20 mediated degradation of Nek2A; Antigen processing: Ubiquitination & Proteasome degradation; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; CDK-mediated phosphorylation and removal of Cdc6; Autodegradation of Cdh1 by Cdh1:APC/C; Assembly of the pre-replicative complex; APC/C:Cdc20 mediated degradation of Cyclin B; Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase; Regulation of APC/C activators between G1/S and early anaphase; Phosphorylation of the APC/C; Senescence-Associated Secretory Phenotype (SASP); Transcriptional Regulation by VENTX; Aberrant regulation of mitotic exit in cancer due to RB1 defects"	"19"	"0"	"42.9"	"26.6"	"41.3"	"37.8"	"31.8"	"39.2"	"51.1"	"94.3"	"102.2"	"292.9"	"405.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TC92"	"Ecto-NOX disulfide-thiol exchanger 1 OS=Homo sapiens OX=9606 GN=ENOX1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"643"	"73.3"	"5.54"	"319.64"	"3.08"	"1"	"1"	"other biological processes"	"non-structural extracellular;plasma membrane;other membranes"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"55068"	"ENSG00000120658"	"ENOX1"	"A4GU15; A6NMH9; B7Z5K1; hsa:55068; Q2TU81; Q5VT11; Q8TC92; Q9NWE0"	""	""	"0"	"0"	"5.2"	"4.7"	"6.5"	"5.1"	"4.8"	"4.3"	"7.1"	"10.8"	"11.7"	"23.1"	"29.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9H7D7"	"WD repeat-containing protein 26 OS=Homo sapiens OX=9606 GN=WDR26 PE=1 SV=3"	""	""	"2"	"1"	"1"	"1"	"661"	"72.1"	"6.16"	""	"3.08"	""	"1"	"protein metabolism;other metabolic processes"	"cytosol;mitochondrion;nucleus;other cell component"	""	"Pf00400, Pf17814"	"80232"	"ENSG00000162923"	"WDR26"	"A0MNN3; hsa:80232; Q4G100; Q59EC4; Q5GLZ9; Q86UY4; Q9H3C2; Q9H7D7"	"Ciliary landscape"	""	"1"	"0"	"13.3"	"7.9"	"13.3"	"13.5"	"12.5"	"11.5"	"14.4"	"25.5"	"22.7"	"66.5"	"117.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00217"	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS8 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"210"	"23.7"	"6.34"	"330.45"	"3.08"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;stress response;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf12838"	"4728"	"ENSG00000110717"	"NDUFS8"	"B2RB86; hsa:4728; O00217; Q0VDA8"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"41.2"	"35.7"	"54.2"	"46.6"	"42.0"	"49.0"	"68.8"	"136.3"	"169.2"	"485.5"	"702.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H6S0"	"3'-5' RNA helicase YTHDC2 OS=Homo sapiens OX=9606 GN=YTHDC2 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1430"	"160.1"	"8.40"	"292.05"	"3.08"	"1"	"1"	"cell cycle OR cell proliferation;other biological processes"	"ER/Golgi;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf01424, Pf04146, Pf04408, Pf07717"	"64848"	"ENSG00000047188"	"YTHDC2"	"B2RP66; hsa:64848; Q9H6S0"	""	""	"0"	"0"	"14.4"	"10.9"	"15.0"	"16.5"	"14.4"	"14.4"	"16.8"	"23.3"	"28.2"	"88.1"	"101.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O96028"	"Histone-lysine N-methyltransferase NSD2 OS=Homo sapiens OX=9606 GN=NSD2 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1365"	"152.2"	"8.69"	"287.81"	"3.07"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00505, Pf00855, Pf00856, Pf17907, Pf17982"	"7468"	"ENSG00000109685"	"NSD2"	"A2A2T2; A2A2T3; A2A2T4; A7MCZ1; D3DVQ2; hsa:7468; O96028; O96031; Q4VBY8; Q672J1; Q6IS00; Q86V01; Q9BZB4; Q9UI92; Q9UPR2"	"4p16.3 copy number variation"	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; PKMTs methylate histone lysines; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; Nonhomologous End-Joining (NHEJ)"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BRJ7"	"Tudor-interacting repair regulator protein OS=Homo sapiens OX=9606 GN=NUDT16L1 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"211"	"23.3"	"8.91"	"366.77"	"3.07"	"1"	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity"	""	"84309"	"ENSG00000168101"	"NUDT16L1"	"hsa:84309; Q8NAI2; Q9BRJ7"	""	""	"0"	"0"	"5.1"	"6.4"	"8.2"	"4.0"	"5.6"	"9.6"	"9.3"	"19.3"	"21.9"	"39.7"	"67.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q969J3"	"BLOC-1-related complex subunit 5 OS=Homo sapiens OX=9606 GN=BORCS5 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"196"	"22.2"	"6.35"	"237.61"	"3.06"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf10158"	"118426"	"ENSG00000165714; ENSG00000280689"	"BORCS5"	"hsa:118426; Q969J3; Q96QS5"	""	""	"0"	"0"	"0.0"	"2.0"	"3.8"	"0.0"	"2.5"	"3.6"	"4.5"	"10.0"	"9.2"	"39.8"	"38.3"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A1L390"	"Pleckstrin homology domain-containing family G member 3 OS=Homo sapiens OX=9606 GN=PLEKHG3 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1219"	"134.3"	"6.55"	"393.12"	"3.06"	"1"	"1"	"other biological processes"	"cytosol;cytoskeleton"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00169, Pf00621"	"26030"	"ENSG00000126822"	"PLEKHG3"	"A1L389; A1L390; B5MEC9; hsa:26030; O60339; Q6GMS3; Q6P4B1; Q7L3S3; Q86SW7; Q8TEF5; Q96EW6; Q9BT82"	""	"RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RHOG GTPase cycle"	"5"	"0"	"57.8"	"54.5"	"58.5"	"58.9"	"52.0"	"63.9"	"69.1"	"111.5"	"127.8"	"198.7"	"264.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q676U5"	"Autophagy-related protein 16-1 OS=Homo sapiens OX=9606 GN=ATG16L1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"607"	"68.2"	"6.64"	"364.37"	"3.06"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00400, Pf08614"	"55054"	"ENSG00000085978; ENSG00000281089"	"ATG16L1"	"A3EXK9; A3EXL0; B6ZDH0; hsa:55054; Q676U5; Q6IPN1; Q6UXW4; Q6ZVZ5; Q8NCY2; Q96JV5; Q9H619"	"Nanoparticle triggered autophagic cell death; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; LDLRAD4 and what we know about it; Autophagy; Clock-controlled autophagy in bone metabolism"	"Macroautophagy"	"6"	"0"	"24.0"	"19.6"	"29.1"	"24.7"	"27.2"	"25.1"	"25.9"	"46.2"	"51.5"	"217.0"	"424.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8IVD9"	"NudC domain-containing protein 3 OS=Homo sapiens OX=9606 GN=NUDCD3 PE=1 SV=3"	""	""	"4"	"1"	"1"	"1"	"361"	"40.8"	"5.25"	""	"3.06"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;other cell component"	"other molecular function"	"Pf04969, Pf14050"	"23386"	"ENSG00000015676"	"NUDCD3"	"hsa:23386; Q8IVD9; Q9BTI3; Q9H7W9; Q9UPT4"	""	""	"0"	"0"	"19.4"	"17.3"	"24.2"	"18.1"	"19.4"	"23.8"	"26.0"	"54.9"	"33.8"	"114.3"	"60.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UPZ3"	"Hermansky-Pudlak syndrome 5 protein OS=Homo sapiens OX=9606 GN=HPS5 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1129"	"127.4"	"5.54"	"361.15"	"3.06"	"1"	"1"	"cell organization and biogenesis;stress response;transport;other biological processes"	"cytosol;other cytoplasmic organelle;other cell component"	""	""	"11234"	"ENSG00000110756; ENSG00000288445"	"HPS5"	"A8K6J8; A8K8S1; D3DQX9; D3DQY0; hsa:11234; O95942; Q8N4U0; Q9UPZ3"	""	""	"0"	"0"	"10.2"	"7.9"	"8.1"	"6.2"	"9.5"	"8.2"	"12.0"	"17.6"	"16.4"	"33.7"	"48.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P1Q9"	"tRNA N(3)-methylcytidine methyltransferase METTL2B OS=Homo sapiens OX=9606 GN=METTL2B PE=1 SV=3"	"0.000"	""	"5"	"1"	"2"	"1"	"378"	"43.4"	"5.86"	"280.83"	"3.05"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"other cell component"	"other molecular function"	"Pf13489"	"55798"	"ENSG00000165055"	"METTL2B"	"B4DZ68; hsa:55798; Q0IJ54; Q3B7J1; Q6P1Q9"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NX14"	"NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFB11 PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"153"	"17.3"	"5.22"	"366.23"	"3.05"	"1"	"1"	"cell organization and biogenesis;other metabolic processes"	"other membranes;mitochondrion"	""	"Pf10183"	"54539"	"ENSG00000147123"	"NDUFB11"	"hsa:54539; Q5JRR3; Q5JRR4; Q6IAB6; Q8WZ96; Q9BXX9; Q9NX14"	"Nonalcoholic fatty liver disease"	"Complex I biogenesis"	"3"	"0"	"68.6"	"57.4"	"72.8"	"65.9"	"71.1"	"66.7"	"84.1"	"124.8"	"142.0"	"259.2"	"346.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09669"	"Cytochrome c oxidase subunit 6C OS=Homo sapiens OX=9606 GN=COX6C PE=1 SV=2"	"0.000"	""	"11"	"1"	"2"	"1"	"75"	"8.8"	"10.39"	"306.76"	"3.05"	"1"	"1"	"other metabolic processes"	"other membranes;mitochondrion"	""	"Pf02937"	"1345"	"ENSG00000164919"	"COX6C"	"B2R4D7; hsa:1345; P09669"	"Electron transport chain: OXPHOS system in mitochondria; Ciliary landscape; Nonalcoholic fatty liver disease; Mitochondrial complex IV assembly; 5q35 copy number variation"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"8"	"0"	"99.5"	"91.2"	"116.5"	"99.5"	"80.9"	"91.5"	"118.8"	"305.6"	"313.8"	"1138.4"	"1556.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14967"	"Calmegin OS=Homo sapiens OX=9606 GN=CLGN PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"610"	"70.0"	"4.69"	"325.25"	"3.04"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf00262"	"1047"	"ENSG00000153132"	"CLGN"	"B3KS90; B4DXV8; D3DNY8; hsa:1047; O14967"	""	""	"0"	"0"	"4.3"	"2.2"	"5.6"	"4.9"	"4.2"	"4.7"	"5.4"	"12.2"	"15.5"	"28.7"	"51.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UGY1"	"Nucleolar protein 12 OS=Homo sapiens OX=9606 GN=NOL12 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"213"	"24.6"	"10.23"	"236.99"	"3.04"	"1"	"1"	""	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf09805"	"79159"	"ENSG00000273899"	"NOL12"	"hsa:79159; Q9UGY1"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"55.4"	"36.3"	"58.1"	"45.8"	"56.6"	"63.6"	"75.4"	"125.0"	"128.6"	"246.2"	"323.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TEQ6"	"Gem-associated protein 5 OS=Homo sapiens OX=9606 GN=GEMIN5 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1508"	"168.5"	"6.62"	"282.72"	"3.03"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf00400, Pf12894"	"25929"	"ENSG00000082516"	"GEMIN5"	"hsa:25929; Q14CV0; Q8TEQ6; Q8WWV4; Q969W4; Q9H9K3; Q9UFI5"	""	"SARS-CoV-2 modulates host translation machinery; snRNP Assembly"	"2"	"0"	"11.4"	"11.4"	"15.2"	"10.7"	"14.9"	"12.1"	"16.0"	"36.6"	"39.1"	"106.5"	"162.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P18615"	"Negative elongation factor E OS=Homo sapiens OX=9606 GN=NELFE PE=1 SV=3"	"0.000"	""	"4"	"2"	"3"	"2"	"380"	"43.2"	"9.33"	"541.53"	"3.03"	"2"	"1"	"other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"7936"	"ENSG00000204356; ENSG00000206268; ENSG00000206357; ENSG00000229363; ENSG00000231044; ENSG00000233801"	"NELFE"	"A2BE08; B4DUN1; B4DYX9; hsa:7936; P18615; Q5JP74; Q5JP75; Q96F56; Q9NPK2"	"Initiation of transcription and translation elongation at the HIV-1 LTR; 4p16.3 copy number variation"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes"	"16"	"0"	"224.2"	"197.9"	"188.8"	"181.2"	"174.8"	"194.3"	"221.3"	"504.9"	"490.7"	"1215.7"	"1413.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52747"	"Zinc finger protein 143 OS=Homo sapiens OX=9606 GN=ZNF143 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"638"	"68.9"	"6.05"	"365.33"	"3.03"	"1"	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00096"	"7702"	"ENSG00000166478"	"ZNF143"	"A8K518; B4DLY5; E7ER34; hsa:7702; O75559; P52747; Q8WUK9"	"IL-18 signaling pathway"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 3 Promoter; RNA polymerase II transcribes snRNA genes"	"4"	"0"	"127.8"	"131.4"	"85.4"	"86.8"	"90.2"	"100.1"	"126.2"	"193.7"	"185.4"	"304.7"	"404.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NFI3"	"Cytosolic endo-beta-N-acetylglucosaminidase OS=Homo sapiens OX=9606 GN=ENGASE PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"743"	"83.9"	"6.79"	"366.17"	"3.03"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol"	"other molecular function"	"Pf03644"	"64772"	"ENSG00000167280"	"ENGASE"	"hsa:64772; Q659F0; Q8NFI3; Q8TB86; Q9H6U4"	""	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"	"1"	"0"	"11.3"	"12.5"	"14.9"	"10.6"	"10.0"	"18.9"	"21.3"	"67.9"	"80.5"	"169.9"	"171.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9P265"	"Disco-interacting protein 2 homolog B OS=Homo sapiens OX=9606 GN=DIP2B PE=1 SV=3"	""	""	"1"	"1"	"1"	"1"	"1576"	"171.4"	"8.09"	""	"3.02"	""	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"cytoskeletal activity"	"Pf00501, Pf06464"	"57609"	"ENSG00000066084"	"DIP2B"	"hsa:57609; Q6B011; Q8N1L5; Q8NB38; Q9P265"	""	""	"0"	"0"	"6.6"	"5.3"	"7.4"	"5.2"	"6.0"	"6.8"	"9.2"	"14.3"	"16.6"	"29.9"	"42.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N9T8"	"Protein KRI1 homolog OS=Homo sapiens OX=9606 GN=KRI1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"703"	"82.5"	"5.14"	"353.99"	"3.02"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf05178, Pf12936"	"65095"	"ENSG00000129347"	"KRI1"	"hsa:65095; Q2M1R5; Q2M1R7; Q7L5J7; Q8N9T8; Q96G92; Q9BU50; Q9H6I1; Q9H978"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N335"	"Glycerol-3-phosphate dehydrogenase 1-like protein OS=Homo sapiens OX=9606 GN=GPD1L PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"351"	"38.4"	"7.02"	"339.92"	"3.02"	"1"	"1"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf01210, Pf07479"	"23171"	"ENSG00000152642"	"GPD1L"	"A8K9U3; hsa:23171; Q14702; Q8N335; Q9BRM5"	"Sudden infant death syndrome (SIDS) susceptibility pathways"	"Synthesis of PA"	"2"	"0"	"60.1"	"48.6"	"64.8"	"49.1"	"48.7"	"49.7"	"59.8"	"156.0"	"151.8"	"399.2"	"652.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q00536"	"Cyclin-dependent kinase 16 OS=Homo sapiens OX=9606 GN=CDK16 PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"496"	"55.7"	"7.62"	""	"3.02"	""	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"5127"	"ENSG00000102225"	"CDK16"	"A8K280; B7Z7C8; hsa:5127; J3KN74; J3KQP7; Q00536"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92575"	"UBX domain-containing protein 4 OS=Homo sapiens OX=9606 GN=UBXN4 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"508"	"56.7"	"6.38"	"358.46"	"3.02"	"1"	"1"	"protein metabolism;other metabolic processes;stress response"	"other membranes;cytosol;ER/Golgi;nucleus"	""	"Pf00789"	"23190"	"ENSG00000144224"	"UBXN4"	"A8K9W4; hsa:23190; Q4ZG56; Q8IYM5; Q92575"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P0V9"	"Septin-10 OS=Homo sapiens OX=9606 GN=SEPTIN10 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"454"	"52.6"	"6.80"	"333.85"	"3.02"	"1"	"1"	"cell cycle OR cell proliferation"	"cytoskeleton;other cell component"	"other molecular function"	"Pf00735"	"151011"	"ENSG00000186522"	"SEPTIN10"	"B3KRQ9; hsa:151011; Q86VP5; Q9HAH6; Q9P0V9"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60825"	"6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"505"	"58.4"	"8.38"	"394.57"	"3.01"	"1"	"1"	"other metabolic processes;other biological processes"	"cytosol;nucleus"	"kinase activity;other molecular function"	"Pf00300, Pf01591"	"5208"	"ENSG00000123836"	"PFKFB2"	"hsa:5208; O60824; O60825; Q5VVQ3; Q5VVQ4; Q9H3P1"	"Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Thyroid hormones production and peripheral downstream signaling effects"	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92504"	"Zinc transporter SLC39A7 OS=Homo sapiens OX=9606 GN=SLC39A7 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"469"	"50.1"	"6.87"	"458.08"	"3.01"	"1"	"1"	"transport;other biological processes"	"other membranes;ER/Golgi;nucleus"	"transporter activity"	"Pf02535"	"7922"	"ENSG00000112473; ENSG00000206288; ENSG00000224399; ENSG00000226614; ENSG00000227402; ENSG00000229802"	"SLC39A7"	"B0UXF6; hsa:7922; Q5STP8; Q92504; Q9UIQ0"	"Nuclear receptors meta-pathway; NRF2 pathway; Zinc homeostasis"	"Zinc influx into cells by the SLC39 gene family"	"4"	"0"	"61.0"	"44.8"	"65.1"	"54.6"	"64.6"	"59.0"	"80.4"	"96.9"	"106.2"	"219.6"	"442.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75529"	"TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L OS=Homo sapiens OX=9606 GN=TAF5L PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"589"	"66.1"	"5.88"	"456.98"	"3.00"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00400, Pf04494"	"27097"	"ENSG00000135801"	"TAF5L"	"hsa:27097; O75529; Q5TDI5; Q5TDI6; Q8IW31"	""	"HATs acetylate histones"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42356"	"Phosphatidylinositol 4-kinase alpha OS=Homo sapiens OX=9606 GN=PI4KA PE=1 SV=4"	"0.000"	""	"2"	"3"	"4"	"3"	"2102"	"236.7"	"7.06"	"870.24"	"3.00"	"3"	"1"	"other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"kinase activity;other molecular function"	"Pf00454, Pf00613, Pf19274"	"5297"	"ENSG00000241973"	"PI4KA"	"hsa:5297; P42356; Q7Z625; Q9UPG2"	"Ectoderm differentiation; 22q11.2 copy number variation syndrome"	"Synthesis of PIPs at the Golgi membrane; Synthesis of PIPs at the ER membrane"	"4"	"0"	"9.2"	"9.5"	"16.6"	"14.6"	"12.6"	"11.7"	"21.7"	"102.3"	"100.8"	"167.3"	"220.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43674"	"NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFB5 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"189"	"21.7"	"9.63"	"299.05"	"3.00"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion;nucleus"	"transporter activity"	"Pf09781"	"4711"	"ENSG00000136521"	"NDUFB5"	"hsa:4711; O43674; Q561V6"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"7.2"	"3.7"	"3.2"	"3.3"	"2.4"	"3.3"	"7.7"	"18.5"	"30.9"	"79.8"	"82.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P78316"	"Nucleolar protein 14 OS=Homo sapiens OX=9606 GN=NOP14 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"857"	"97.6"	"7.58"	"589.24"	"2.99"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04147"	"8602"	"ENSG00000087269"	"NOP14"	"D3DVR6; hsa:8602; P78316; Q7LGI5; Q7Z6K0; Q8TBR6"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"52.8"	"52.8"	"54.4"	"55.3"	"62.6"	"62.7"	"59.8"	"93.5"	"98.2"	"151.6"	"175.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5JVF3"	"PCI domain-containing protein 2 OS=Homo sapiens OX=9606 GN=PCID2 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"399"	"46.0"	"8.53"	"301.69"	"2.99"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf01399"	"55795"	"ENSG00000126226"	"PCID2"	"A6NK09; hsa:55795; Q3ZCX1; Q5JVF3; Q5TC57; Q5TC58; Q9H7K1; Q9HBZ7; Q9NUK6; Q9NVY1; Q9NW44; Q9NWH3"	""	""	"0"	"0"	"30.1"	"24.5"	"47.0"	"36.0"	"25.1"	"34.7"	"51.1"	"89.4"	"96.3"	"232.7"	"295.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VSL9"	"Striatin-interacting protein 1 OS=Homo sapiens OX=9606 GN=STRIP1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"837"	"95.5"	"6.29"	"328.42"	"2.99"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf07923, Pf11882"	"85369"	"ENSG00000143093"	"STRIP1"	"hsa:85369; Q0V925; Q5VSL8; Q5VSL9; Q658K2; Q6ZV31; Q8N598; Q96SN2; Q9C0A2"	""	""	"0"	"0"	"23.3"	"19.0"	"23.0"	"23.0"	"20.3"	"24.6"	"30.6"	"49.2"	"53.5"	"118.7"	"178.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H270"	"Vacuolar protein sorting-associated protein 11 homolog OS=Homo sapiens OX=9606 GN=VPS11 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"941"	"107.8"	"7.05"	"281.33"	"2.99"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00637, Pf12451, Pf13923"	"55823"	""	"VPS11"	"hsa:55823; Q8WY89; Q96EP8; Q9H270; Q9H6D9; Q9HCS6"	"Network map of SARS-CoV-2 signaling pathway"	"SARS-CoV-2 modulates autophagy"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WTS6"	"Histone-lysine N-methyltransferase SETD7 OS=Homo sapiens OX=9606 GN=SETD7 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"366"	"40.7"	"4.63"	"338.18"	"2.99"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00856, Pf02493"	"80854"	"ENSG00000145391"	"SETD7"	"B5WWL3; hsa:80854; Q0VAH3; Q4W5A9; Q8WTS6; Q9C0E6"	"Histone modifications"	"PKMTs methylate histone lysines"	"2"	"0"	"81.8"	"72.1"	"64.2"	"68.5"	"66.4"	"73.0"	"81.8"	"125.9"	"111.1"	"193.5"	"233.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TBB5"	"Kelch domain-containing protein 4 OS=Homo sapiens OX=9606 GN=KLHDC4 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"520"	"57.9"	"5.72"	"295.96"	"2.99"	"1"	"1"	""	""	""	"Pf07646, Pf13418, Pf13854, Pf13964"	"54758"	"ENSG00000104731"	"KLHDC4"	"D3DUN3; D3DUN4; D3DUN5; hsa:54758; Q8TBB5; Q96F29; Q9BVN3"	""	""	"0"	"0"	"3.0"	"3.6"	"5.6"	"2.9"	"4.3"	"6.3"	"7.9"	"20.9"	"20.4"	"77.4"	"63.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q07864"	"DNA polymerase epsilon catalytic subunit A OS=Homo sapiens OX=9606 GN=POLE PE=1 SV=5"	"0.000"	""	"0"	"1"	"2"	"1"	"2286"	"261.4"	"6.39"	"329.35"	"2.99"	"1"	"1"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;developmental processes"	"plasma membrane;other membranes;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00136, Pf03104, Pf08490"	"5426"	"ENSG00000177084"	"POLE"	"hsa:5426; Q07864; Q13533; Q86VH9"	"Retinoblastoma gene in cancer; Pyrimidine metabolism; G1 to S cell cycle control; DNA replication; Base excision repair; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Activation of the pre-replicative complex; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; DNA replication initiation; Gap-filling DNA repair synthesis and ligation in GG-NER"	"19"	"0"	"42.8"	"38.5"	"48.6"	"35.4"	"39.3"	"35.6"	"59.2"	"84.2"	"78.1"	"157.5"	"225.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BUL8"	"Programmed cell death protein 10 OS=Homo sapiens OX=9606 GN=PDCD10 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"212"	"24.7"	"8.19"	"336.40"	"2.99"	"1"	"1"	"cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf06840"	"11235"	"ENSG00000114209"	"PDCD10"	"A8K515; D3DNN5; hsa:11235; O14811; Q9BUL8"	""	""	"0"	"0"	"89.0"	"59.4"	"96.1"	"88.2"	"83.3"	"90.4"	"112.3"	"195.0"	"167.5"	"472.4"	"790.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96TA1"	"Protein Niban 2 OS=Homo sapiens OX=9606 GN=NIBAN2 PE=1 SV=3"	""	""	"3"	"1"	"1"	"1"	"746"	"84.1"	"6.19"	""	"2.98"	""	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	""	"64855"	"ENSG00000136830"	"NIBAN2"	"hsa:64855; Q4LE55; Q5VVW6; Q5VVW7; Q96TA1; Q9BUS2; Q9NT35"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96KQ4"	"Apoptosis-stimulating of p53 protein 1 OS=Homo sapiens OX=9606 GN=PPP1R13B PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1090"	"119.5"	"6.76"	"372.42"	"2.98"	"1"	"1"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00018, Pf00023"	"23368"	"ENSG00000088808"	"PPP1R13B"	"B2RMX5; hsa:23368; O94870; Q96KQ4"	""	"TP53 Regulates Transcription of Death Receptors and Ligands; Activation of PUMA and translocation to mitochondria; TP53 Regulates Transcription of Genes Involved in Cytochrome C Release; TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain; Regulation of TP53 Activity through Association with Co-factors"	"5"	"0"	"30.8"	"32.4"	"31.1"	"35.4"	"30.2"	"33.0"	"37.5"	"43.8"	"45.3"	"84.8"	"95.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NFY9"	"Kelch repeat and BTB domain-containing protein 8 OS=Homo sapiens OX=9606 GN=KBTBD8 PE=1 SV=2"	"0.000"	""	"4"	"2"	"3"	"2"	"601"	"68.8"	"6.29"	"844.75"	"2.98"	"2"	"1"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;other cell component"	""	"Pf00651, Pf01344, Pf07707"	"84541"	"ENSG00000163376"	"KBTBD8"	"B4DTW6; hsa:84541; Q8NFY9; Q96JI5"	""	"Antigen processing: Ubiquitination & Proteasome degradation; Neddylation"	"2"	"0"	"0.0"	"3.9"	"2.7"	"3.3"	"4.5"	"9.7"	"17.2"	"100.4"	"103.8"	"179.8"	"184.7"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TC07"	"TBC1 domain family member 15 OS=Homo sapiens OX=9606 GN=TBC1D15 PE=1 SV=2"	"0.001"	""	"1"	"1"	"2"	"1"	"691"	"79.4"	"5.67"	"233.28"	"2.97"	"1"	"1"	"other biological processes"	"non-structural extracellular;other cell component"	"enzyme regulator activity"	"Pf00566, Pf12068"	"64786"	"ENSG00000121749"	"TBC1D15"	"B4DMT9; B9A6L6; hsa:64786; J3KNI9; Q8TC07; Q9HA83"	""	"TBC/RABGAPs"	"1"	"0"	"4.0"	"4.8"	"7.1"	"6.8"	"5.7"	"4.5"	"9.3"	"23.3"	"21.8"	"60.4"	"92.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O14893"	"Gem-associated protein 2 OS=Homo sapiens OX=9606 GN=GEMIN2 PE=1 SV=1"	""	""	"8"	"1"	"1"	"1"	"280"	"31.6"	"5.58"	""	"2.97"	""	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf04938"	"8487"	"ENSG00000092208"	"GEMIN2"	"B2R9W8; hsa:8487; O14893; Q2M3B3; Q9H4F5; Q9NS77; Q9NS78; Q9NS79"	""	"snRNP Assembly; SARS-CoV-2 modulates host translation machinery"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q06547"	"GA-binding protein subunit beta-1 OS=Homo sapiens OX=9606 GN=GABPB1 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"395"	"42.5"	"4.86"	"429.94"	"2.97"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf12796"	"2553"	"ENSG00000104064"	"GABPB1"	"A8IE52; hsa:2553; Q06545; Q06547; Q12940; Q12941; Q12942; Q8IYD0"	"Myometrial relaxation and contraction pathways; Hematopoietic stem cell gene regulation by GABP alpha/beta complex; Mitochondrial gene expression"	""	"3"	"0"	"4.7"	"8.5"	"4.6"	"6.0"	"7.1"	"5.0"	"4.4"	"47.1"	"56.3"	"127.1"	"208.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P63218"	"Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 OS=Homo sapiens OX=9606 GN=GNG5 PE=1 SV=3"	""	""	"13"	"1"	"1"	"1"	"68"	"7.3"	"9.85"	""	"2.96"	""	"1"	"signal transduction"	"plasma membrane;other membranes"	"other molecular function"	"Pf00631"	"2787"	"ENSG00000174021"	"GNG5"	"B2R5A0; hsa:2787; P30670; P63218; Q5VX54; Q61015"	"Myometrial relaxation and contraction pathways; G protein signaling pathways; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Ras signaling; Calcium regulation in cardiac cells"	"G alpha (12/13) signalling events; G alpha (q) signalling events; G alpha (i) signalling events; G alpha (z) signalling events; ADP signalling through P2Y purinoceptor 12; Extra-nuclear estrogen signaling; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production; Thrombin signalling through proteinase activated receptors (PARs); Activation of G protein gated Potassium channels; G-protein activation; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; G beta:gamma signalling through PI3Kgamma; Prostacyclin signalling through prostacyclin receptor; Adrenaline,noradrenaline inhibits insulin secretion; Ca2+ pathway; G beta:gamma signalling through PLC beta; ADP signalling through P2Y purinoceptor 1; Glucagon-type ligand receptors; Thromboxane signalling through TP receptor; Vasopressin regulates renal water homeostasis via Aquaporins; Presynaptic function of Kainate receptors; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; G beta:gamma signalling through BTK; G beta:gamma signalling through CDC42; Inhibition  of voltage gated Ca2+ channels via Gbeta/gamma subunits; Glucagon signaling in metabolic regulation"	"35"	"0"	"73.5"	"46.3"	"62.2"	"66.6"	"59.4"	"59.7"	"70.7"	"245.1"	"237.9"	"770.2"	"1131.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N983"	"39S ribosomal protein L43, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL43 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"215"	"23.4"	"8.65"	"281.61"	"2.96"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf05047"	"84545"	"ENSG00000055950"	"MRPL43"	"B1AL06; B1AL07; B1AL09; B1AL10; C9J5Q3; D3DR71; hsa:84545; Q5JW06; Q7Z719; Q7Z7H6; Q86XN1; Q8N983; Q9BYC7"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"23.3"	"19.0"	"23.2"	"27.1"	"28.6"	"22.9"	"30.8"	"52.9"	"55.8"	"122.3"	"174.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NFD5"	"AT-rich interactive domain-containing protein 1B OS=Homo sapiens OX=9606 GN=ARID1B PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"2236"	"236.0"	"6.73"	"417.39"	"2.96"	"1"	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"25.2"	"16.5"	"24.8"	"25.8"	"19.3"	"29.5"	"25.0"	"39.7"	"44.6"	"66.7"	"110.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14258"	"E3 ubiquitin/ISG15 ligase TRIM25 OS=Homo sapiens OX=9606 GN=TRIM25 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"630"	"70.9"	"8.09"	"253.89"	"2.95"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00622, Pf13445, Pf13765"	"7706"	"ENSG00000121060"	"TRIM25"	"hsa:7706; Q14258"	"Novel intracellular components of RIG-I-like receptor pathway; Cytosolic DNA-sensing pathway; SARS-CoV-2 innate immunity evasion and cell-specific immune response; 1p36 copy number variation syndrome"	"SARS-CoV-1 activates/modulates innate immune responses; ISG15 antiviral mechanism; Interferon gamma signaling; SARS-CoV-2 activates/modulates innate and adaptive immune responses; TRAF6 mediated NF-kB activation; NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10; Termination of translesion DNA synthesis; Negative regulators of DDX58/IFIH1 signaling; Ovarian tumor domain proteases; TRAF3-dependent IRF activation pathway; TRAF6 mediated IRF7 activation"	"16"	"0"	"10.3"	"7.0"	"11.0"	"9.6"	"11.1"	"12.8"	"15.5"	"51.1"	"48.0"	"104.5"	"146.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H089"	"Large subunit GTPase 1 homolog OS=Homo sapiens OX=9606 GN=LSG1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"658"	"75.2"	"6.38"	"339.66"	"2.95"	"1"	"1"	"transport"	"cytosol;ER/Golgi;nucleus"	"other molecular function"	"Pf01926"	"55341"	"ENSG00000041802"	"LSG1"	"A0JLT4; A0PJK3; A6NI18; hsa:55341; Q7L9H8; Q9H089; Q9NUK8"	""	""	"0"	"0"	"90.4"	"49.8"	"82.6"	"86.0"	"76.8"	"78.8"	"103.5"	"178.4"	"193.1"	"430.7"	"532.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TED0"	"U3 small nucleolar RNA-associated protein 15 homolog OS=Homo sapiens OX=9606 GN=UTP15 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"518"	"58.4"	"9.11"	"330.71"	"2.94"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"ER/Golgi;nucleus;other cell component"	""	"Pf00400, Pf09384"	"84135"	"ENSG00000164338"	"UTP15"	"B4DU75; B4DXK8; hsa:84135; Q6IA60; Q8TED0; Q96E08; Q9H9F8"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q4U2R6"	"39S ribosomal protein L51, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL51 PE=1 SV=1"	"0.000"	""	"9"	"1"	"3"	"1"	"128"	"15.1"	"11.27"	"738.82"	"2.93"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf10244"	"51258"	"ENSG00000111639"	"MRPL51"	"hsa:51258; Q4U2R6; Q96Q57; Q9BQ36; Q9P0N7"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"54.9"	"45.7"	"67.5"	"59.6"	"60.4"	"53.0"	"78.1"	"138.0"	"147.2"	"331.6"	"578.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UPN7"	"Serine/threonine-protein phosphatase 6 regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PPP6R1 PE=1 SV=5"	"0.000"	""	"1"	"1"	"2"	"1"	"881"	"96.7"	"4.55"	"241.08"	"2.93"	"1"	"1"	"other biological processes"	"cytosol;nucleus"	"enzyme regulator activity;other molecular function"	"Pf04499"	"22870"	"ENSG00000105063"	"PPP6R1"	"hsa:22870; Q2M2H3; Q504V2; Q6NVJ6; Q9BU97; Q9UPN7"	""	"COPII-mediated vesicle transport"	"1"	"0"	"15.0"	"17.3"	"14.6"	"14.1"	"12.4"	"15.5"	"18.6"	"36.4"	"38.1"	"68.1"	"97.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y5V0"	"Zinc finger protein 706 OS=Homo sapiens OX=9606 GN=ZNF706 PE=1 SV=1"	""	""	"14"	"1"	"1"	"1"	"76"	"8.5"	"10.01"	""	"2.93"	""	"1"	"other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf04419, Pf12874"	"51123"	"ENSG00000120963"	"ZNF706"	"A8K362; hsa:51123; Q9Y5V0"	""	"Generic Transcription Pathway"	"1"	"0"	"186.7"	"199.0"	"140.8"	"161.2"	"176.9"	"129.1"	"199.7"	"321.7"	"246.5"	"252.3"	"222.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P29590"	"Protein PML OS=Homo sapiens OX=9606 GN=PML PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"882"	"97.5"	"6.21"	"349.27"	"2.93"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00643, Pf12126"	"5371"	"ENSG00000140464"	"PML"	"E9PBR7; hsa:5371; P29590; P29591; P29592; P29593; Q00755; Q15959; Q59FP9; Q8WUA0; Q96S41; Q9BPW2; Q9BWP7; Q9BZX6; Q9BZX7; Q9BZX8; Q9BZX9; Q9BZY0; Q9BZY2; Q9BZY3"	"miRNA regulation of DNA damage response; Wnt/beta-catenin signaling pathway in leukemia; p53 transcriptional gene network; DNA damage response"	"Regulation of PTEN localization; HCMV Early Events; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Interferon gamma signaling; Regulation of TP53 Activity through Acetylation; Regulation of RUNX1 Expression and Activity"	"11"	"0"	"21.2"	"10.5"	"16.5"	"23.8"	"9.7"	"18.2"	"27.7"	"27.1"	"35.4"	"56.5"	"107.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NQS7"	"Inner centromere protein OS=Homo sapiens OX=9606 GN=INCENP PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"918"	"105.4"	"9.44"	"253.47"	"2.93"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf03941, Pf12178"	"3619"	"ENSG00000149503"	"INCENP"	"A8MQD2; hsa:3619; Q5Y192; Q9NQS7"	""	"SUMOylation of DNA replication proteins; RHO GTPases Activate Formins; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"7"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3C4"	"EKC/KEOPS complex subunit TPRKB OS=Homo sapiens OX=9606 GN=TPRKB PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"175"	"19.6"	"6.79"	"310.09"	"2.92"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf08617"	"51002"	"ENSG00000144034"	"TPRKB"	"D6W5H6; hsa:51002; Q8IWR6; Q8IWR7; Q9H3K4; Q9Y3C4"	""	"tRNA modification in the nucleus and cytosol"	"1"	"0"	"236.1"	"186.5"	"235.6"	"198.0"	"190.8"	"198.4"	"281.6"	"453.7"	"415.1"	"1017.6"	"1745.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14854"	"Cytochrome c oxidase subunit 6B1 OS=Homo sapiens OX=9606 GN=COX6B1 PE=1 SV=2"	"0.000"	""	"17"	"1"	"2"	"1"	"86"	"10.2"	"7.05"	"328.73"	"2.92"	"1"	"1"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf02297"	"1340"	"ENSG00000126267"	"COX6B1"	"B2R5C9; hsa:1340; P14854; Q6IBL4"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex IV assembly; 5q35 copy number variation"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"7"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NP81"	"Serine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=SARS2 PE=1 SV=1"	"0.000"	""	"4"	"2"	"3"	"2"	"518"	"58.2"	"8.13"	"566.44"	"2.92"	"2"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00587"	"54938"	"ENSG00000104835; ENSG00000283104"	"SARS2"	"A6NHW7; B4DE10; hsa:54938; Q9BVP3; Q9NP81"	""	"Mitochondrial tRNA aminoacylation"	"1"	"0"	"31.7"	"25.6"	"46.7"	"39.3"	"31.8"	"33.2"	"54.4"	"79.0"	"96.5"	"199.7"	"292.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TDD1"	"ATP-dependent RNA helicase DDX54 OS=Homo sapiens OX=9606 GN=DDX54 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"881"	"98.5"	"10.02"	"458.48"	"2.92"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"ER/Golgi;nucleus"	"signal transduction activity or receptor binding;other molecular function"	"Pf00270, Pf00271, Pf08147"	"79039"	"ENSG00000123064"	"DDX54"	"hsa:79039; Q86YT8; Q8TDD1; Q9BRZ1"	""	""	"0"	"0"	"20.2"	"14.9"	"17.7"	"17.1"	"17.6"	"19.8"	"24.4"	"27.1"	"30.2"	"61.5"	"91.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IWV7"	"E3 ubiquitin-protein ligase UBR1 OS=Homo sapiens OX=9606 GN=UBR1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1749"	"200.1"	"6.01"	"276.42"	"2.92"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf02207, Pf02617, Pf18995"	"197131"	"ENSG00000159459"	"UBR1"	"hsa:197131; O60708; O75492; Q14D45; Q68DN9; Q8IWV7; Q8IWY6; Q96JY4"	""	"Antigen processing: Ubiquitination & Proteasome degradation"	"1"	"0"	"13.0"	"12.0"	"7.4"	"13.4"	"12.1"	"10.1"	"12.2"	"22.2"	"21.1"	"46.5"	"68.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43488"	"Aflatoxin B1 aldehyde reductase member 2 OS=Homo sapiens OX=9606 GN=AKR7A2 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"359"	"39.6"	"7.17"	"351.68"	"2.92"	"1"	"1"	"other metabolic processes"	"cytosol;mitochondrion;ER/Golgi;other cell component"	"other molecular function"	"Pf00248"	"8574"	"ENSG00000053371"	"AKR7A2"	"hsa:8574; O43488; O75749; Q5TG63"	"Aflatoxin B1 metabolism; Metapathway biotransformation Phase I and II"	"Aflatoxin activation and detoxification"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30622"	"CAP-Gly domain-containing linker protein 1 OS=Homo sapiens OX=9606 GN=CLIP1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1438"	"162.1"	"5.36"	"355.06"	"2.91"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01302, Pf16641"	"6249"	"ENSG00000130779"	"CLIP1"	"A0AVD3; hsa:6249; P30622; Q17RS4; Q29RG0"	"Microtubule cytoskeleton regulation; PAFAH1B1 copy number variation"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases activate IQGAPs; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"9"	"0"	"5.6"	"7.2"	"6.2"	"5.6"	"5.2"	"8.2"	"10.6"	"15.3"	"11.3"	"35.1"	"45.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96CF2"	"Charged multivesicular body protein 4c OS=Homo sapiens OX=9606 GN=CHMP4C PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"233"	"26.4"	"6.07"	"405.58"	"2.91"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf03357"	"92421"	"ENSG00000164695"	"CHMP4C"	"B2RBZ1; hsa:92421; Q96CF2"	""	"Sealing of the nuclear envelope (NE) by ESCRT-III; Pyroptosis; HCMV Late Events; Budding and maturation of HIV virion; Endosomal Sorting Complex Required For Transport (ESCRT); Late endosomal microautophagy; Macroautophagy; Translation of Replicase and Assembly of the Replication Transcription Complex; Translation of Replicase and Assembly of the Replication Transcription Complex"	"9"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15649"	"Zinc finger HIT domain-containing protein 3 OS=Homo sapiens OX=9606 GN=ZNHIT3 PE=1 SV=2"	"0.000"	""	"8"	"1"	"2"	"1"	"155"	"17.6"	"5.67"	"357.72"	"2.91"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf04438"	"9326"	"ENSG00000273611; ENSG00000278574"	"ZNHIT3"	"A8K493; hsa:9326; K7EQP1; Q15649; Q8WVJ3"	"17q12 copy number variation syndrome"	""	"1"	"0"	"40.6"	"45.5"	"55.7"	"55.1"	"49.9"	"37.8"	"55.6"	"86.7"	"94.5"	"161.7"	"203.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NW08"	"DNA-directed RNA polymerase III subunit RPC2 OS=Homo sapiens OX=9606 GN=POLR3B PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1133"	"127.7"	"8.50"	"271.57"	"2.90"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00562, Pf04560, Pf04561, Pf04563, Pf04565, Pf04566, Pf04567"	"55703"	"ENSG00000013503"	"POLR3B"	"A8K6H0; B3KV73; F5H1E6; hsa:55703; Q9NW08; Q9NW59"	"Pyrimidine metabolism; Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation"	"10"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TB45"	"DEP domain-containing mTOR-interacting protein OS=Homo sapiens OX=9606 GN=DEPTOR PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"409"	"46.3"	"8.07"	"326.48"	"2.89"	"1"	"1"	"cell organization and biogenesis;signal transduction;other biological processes"	""	""	"Pf00610"	"64798"	"ENSG00000155792"	"DEPTOR"	"B2RCL9; B4DN97; E7EV87; hsa:64798; Q8TB45; Q96EQ1; Q9H0R7; Q9H894; Q9HA07"	"Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; Clear cell renal cell carcinoma pathways; Fragile X syndrome; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Autophagy; p53 transcriptional gene network; Pleural mesothelioma; Network map of SARS-CoV-2 signaling pathway; DYRK1A involvement regarding cell proliferation in brain development"	""	"9"	"0"	"7.3"	"6.7"	"13.4"	"7.9"	"7.7"	"6.0"	"11.7"	"32.1"	"41.3"	"82.0"	"81.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2X7"	"ARF GTPase-activating protein GIT1 OS=Homo sapiens OX=9606 GN=GIT1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"761"	"84.3"	"6.80"	"267.02"	"2.89"	"1"	"1"	"transport;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;mitochondrion;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf01412, Pf08518, Pf12205, Pf12796, Pf16559"	"28964"	"ENSG00000108262"	"GIT1"	"B4DGU9; B4DSV3; hsa:28964; Q86SS0; Q9BRJ4; Q9Y2X7"	"CAMKK2 pathway; Regulation of actin cytoskeleton"	"RHOJ GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOV GTPase cycle; RHOU GTPase cycle; Ephrin signaling; Activation of RAC1 downstream of NMDARs"	"12"	"0"	"56.5"	"44.1"	"59.9"	"48.1"	"59.1"	"65.8"	"67.9"	"133.0"	"125.7"	"250.2"	"343.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52732"	"Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1056"	"119.1"	"5.64"	"252.52"	"2.89"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225, Pf13931"	"3832"	"ENSG00000138160"	"KIF11"	"A0AV49; B2RMV3; hsa:3832; P52732; Q15716; Q5VWX0"	""	"COPI-dependent Golgi-to-ER retrograde traffic; MHC class II antigen presentation; Kinesins"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BYI3"	"Hyccin OS=Homo sapiens OX=9606 GN=FAM126A PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"521"	"57.6"	"8.16"	"312.53"	"2.89"	"1"	"1"	"other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf09790"	"84668"	"ENSG00000122591"	"HYCC1"	"A0A024RA06; A4D145; B8ZZJ1; hsa:84668; Q6N010; Q75MR4; Q7LDZ4; Q96MX1; Q96NQ6; Q9BYI3"	""	""	"0"	"0"	"37.2"	"31.8"	"36.6"	"31.2"	"29.1"	"42.8"	"54.3"	"147.1"	"173.2"	"282.5"	"341.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09622"	"Dihydrolipoyl dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=DLD PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"509"	"54.1"	"7.85"	"376.66"	"2.89"	"1"	"1"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytoskeleton;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf02852, Pf07992"	"1738"	"ENSG00000091140"	"DLD"	"B2R5X0; B4DHG0; B4DT69; hsa:1738; P09622; Q14131; Q14167; Q59EV8; Q8WTS4"	"Fatty acid beta-oxidation; TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Tryptophan metabolism; 7q11.23 copy number variation syndrome; Neuroinflammation and glutamatergic signaling; Glycolysis and gluconeogenesis; 10q11.21q11.23 copy number variation syndrome; Metabolic Epileptic Disorders; TCA cycle (aka Krebs or citric acid cycle)"	"Lysine catabolism; Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid; Citric acid cycle (TCA cycle); Branched-chain amino acid catabolism; Glycine degradation"	"18"	"0"	"105.7"	"74.7"	"83.7"	"79.4"	"88.8"	"110.5"	"132.3"	"237.0"	"287.8"	"931.9"	"1229.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6PII3"	"Coiled-coil domain-containing protein 174 OS=Homo sapiens OX=9606 GN=CCDC174 PE=1 SV=3"	"0.000"	""	"3"	"2"	"3"	"1"	"467"	"53.9"	"6.33"	"645.75"	"2.88"	"2"	"1"	""	"nucleus"	""	"Pf13300"	"51244"	"ENSG00000154781"	"CCDC174"	"hsa:51244; Q6PII3; Q96CS5"	""	""	"0"	"0"	"68.7"	"68.0"	"50.1"	"50.4"	"47.5"	"53.2"	"73.9"	"108.9"	"107.8"	"163.0"	"192.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q13049"	"E3 ubiquitin-protein ligase TRIM32 OS=Homo sapiens OX=9606 GN=TRIM32 PE=1 SV=2"	""	""	"4"	"1"	"1"	"1"	"653"	"71.9"	"6.98"	""	"2.88"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf01436, Pf13445"	"22954"	"ENSG00000119401"	"TRIM32"	"hsa:22954; Q13049; Q9NQP8"	"Ciliopathies; Bardet-Biedl syndrome"	"Antigen processing: Ubiquitination & Proteasome degradation; Regulation of innate immune responses to cytosolic DNA"	"4"	"0"	"10.5"	"11.2"	"9.5"	"10.3"	"10.2"	"6.9"	"14.0"	"17.8"	"16.7"	"31.8"	"41.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6ZN17"	"Protein lin-28 homolog B OS=Homo sapiens OX=9606 GN=LIN28B PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"250"	"27.1"	"8.91"	"445.54"	"2.88"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00098, Pf00313"	"389421"	"ENSG00000187772"	"LIN28B"	"A1L165; B2RPN6; hsa:389421; Q5TCM4; Q6ZN17"	"Cardiac progenitor differentiation; Hippo-Merlin signaling dysregulation; Pleural mesothelioma; CCL18 signaling pathway"	""	"4"	"0"	"88.3"	"71.2"	"98.6"	"90.5"	"90.3"	"92.5"	"101.2"	"138.6"	"117.0"	"198.9"	"260.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95817"	"BAG family molecular chaperone regulator 3 OS=Homo sapiens OX=9606 GN=BAG3 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"575"	"61.6"	"6.95"	"316.90"	"2.88"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00397, Pf02179"	"9531"	"ENSG00000151929"	"BAG3"	"A8K5L8; hsa:9531; O95817; Q3B763; Q9NT20; Q9P120"	"Cell interactions of the pancreatic cancer microenvironment"	"Regulation of HSF1-mediated heat shock response"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q13371"	"Phosducin-like protein OS=Homo sapiens OX=9606 GN=PDCL PE=1 SV=3"	""	""	"6"	"1"	"2"	"1"	"301"	"34.3"	"4.73"	""	"2.88"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"cytosol;other cell component"	""	"Pf02114"	"5082"	"ENSG00000136940"	"PDCL"	"hsa:5082; Q13371; Q4VXB6; Q96AF1; Q9UEW7; Q9UFL0; Q9UNX1; Q9UNX2"	""	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"	"1"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"2.8"	"0.0"	"3.0"	"52.7"	"52.1"	"228.9"	"248.5"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P48507"	"Glutamate--cysteine ligase regulatory subunit OS=Homo sapiens OX=9606 GN=GCLM PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"274"	"30.7"	"6.02"	"426.06"	"2.87"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;stress response;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00248"	"2730"	"ENSG00000023909"	"GCLM"	"A8K334; D3DT45; hsa:2730; M5A959; P48507; Q6FHC1; Q9NPX9; Q9NU74"	"Glutathione metabolism; Trans-sulfuration pathway; Trans-sulfuration, one-carbon metabolism and related pathways; Nuclear receptors meta-pathway; NRF2 pathway; Transcriptional activation by NRF2 in response to phytochemicals; Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling; Amino acid metabolism; Ferroptosis; NRF2-ARE regulation; Antiviral and anti-inflammatory effects of Nrf2 on SARS-CoV-2 pathway"	"Glutathione synthesis and recycling; NFE2L2 regulating anti-oxidant/detoxification enzymes; Defective GCLC causes HAGGSD"	"14"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30307"	"M-phase inducer phosphatase 3 OS=Homo sapiens OX=9606 GN=CDC25C PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"473"	"53.3"	"6.79"	"364.60"	"2.87"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00581, Pf06617"	"995"	"ENSG00000158402"	"CDC25C"	"D3DQB8; hsa:995; P30307; Q96PL3; Q9H168; Q9H2E8; Q9H2E9; Q9H2F1"	"miRNA regulation of DNA damage response; Cell cycle; ATM signaling pathway; p53 transcriptional gene network; CCL18 signaling pathway; DNA damage response; Monoamine transport"	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain; Activation of ATR in response to replication stress; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RHO GTPases activate PKNs; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Cyclin A/B1/B2 associated events during G2/M transition; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models; Polo-like kinase mediated events"	"15"	"0"	"7.6"	"8.4"	"9.9"	"13.0"	"7.2"	"12.9"	"17.0"	"31.3"	"33.8"	"43.0"	"45.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P17096"	"High mobility group protein HMG-I/HMG-Y OS=Homo sapiens OX=9606 GN=HMGA1 PE=1 SV=3"	"0.000"	""	"25"	"2"	"3"	"2"	"107"	"11.7"	"10.32"	"1152.28"	"2.87"	"2"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	""	"3159"	"ENSG00000137309"	"HMGA1"	"hsa:3159; P10910; P17096; Q5T6U9; Q9UKB0"	"Adipogenesis; Pre-implantation embryo; Male infertility; 7q11.23 copy number variation syndrome; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Orexin receptor pathway"	"Vpr-mediated nuclear import of PICs; 2-LTR circle formation; Integration of viral DNA into host genomic DNA; Autointegration results in viral DNA circles; APOBEC3G mediated resistance to HIV-1 infection; Formation of Senescence-Associated Heterochromatin Foci (SAHF)"	"13"	"0"	"110.2"	"96.6"	"142.9"	"123.0"	"130.0"	"129.2"	"157.0"	"204.9"	"215.0"	"412.5"	"466.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q2M2I8"	"AP2-associated protein kinase 1 OS=Homo sapiens OX=9606 GN=AAK1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"961"	"103.8"	"6.60"	"368.42"	"2.87"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"signal transduction activity or receptor binding;kinase activity;other molecular function"	"Pf00069"	"22848"	"ENSG00000115977"	"AAK1"	"hsa:22848; Q2M2I8; Q4ZFZ3; Q53RX6; Q9UPV4"	""	"Cargo recognition for clathrin-mediated endocytosis"	"2"	"0"	"12.6"	"13.3"	"11.8"	"10.7"	"8.7"	"10.5"	"16.3"	"29.3"	"32.2"	"74.4"	"90.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19623"	"Spermidine synthase OS=Homo sapiens OX=9606 GN=SRM PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"302"	"33.8"	"5.49"	"354.09"	"2.87"	"1"	"1"	"other metabolic processes;other biological processes"	"cytosol"	"other molecular function"	"Pf01564, Pf17284"	"6723"	"ENSG00000116649"	"SRM"	"B1AKP9; hsa:6723; P19623; Q15511"	"Methionine de novo and salvage pathway; Amino acid metabolism"	"Metabolism of polyamines"	"3"	"0"	"107.0"	"81.6"	"90.6"	"99.6"	"82.8"	"87.8"	"100.2"	"146.5"	"163.7"	"254.4"	"351.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92793"	"CREB-binding protein OS=Homo sapiens OX=9606 GN=CREBBP PE=1 SV=3"	"0.000"	""	"0"	"1"	"2"	"1"	"2442"	"265.2"	"8.53"	"277.20"	"2.86"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00439, Pf00569, Pf02135, Pf02172, Pf06001, Pf08214, Pf09030"	"1387"	"ENSG00000005339"	"CREBBP"	"D3DUC9; hsa:1387; O00147; Q16376; Q4LE28; Q92793"	"Androgen receptor signaling pathway; Angiogenesis; TNF-alpha signaling pathway; Notch signaling; Initiation of transcription and translation elongation at the HIV-1 LTR; IL6 signaling pathway; Pathways affected in adenoid cystic carcinoma; Hematopoietic stem cell gene regulation by GABP alpha/beta complex; VEGFA-VEGFR2 signaling; Wnt signaling pathway and pluripotency; Clear cell renal cell carcinoma pathways; Ebola virus infection in host; Type 2 papillary renal cell carcinoma; Ciliary landscape; Hepatitis B infection; Male infertility; TGF-beta receptor signaling in skeletal dysplasias; Overlap between signal transduction pathways contributing to LMNA laminopathies; 15q13.3 copy number variation syndrome; Urotensin-II-mediated signaling pathway; 15q11q13 copy number variation; TGF-beta receptor signaling; Sudden infant death syndrome (SIDS) susceptibility pathways"	"SUMOylation of transcription cofactors; Formation of paraxial mesoderm; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Pre-NOTCH Transcription and Translation; NOTCH1 Intracellular Domain Regulates Transcription; Notch-HLH transcription pathway; NOTCH3 Intracellular Domain Regulates Transcription; Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells; NOTCH4 Intracellular Domain Regulates Transcription; RUNX3 regulates NOTCH signaling; SARS-CoV-2 activates/modulates innate and adaptive immune responses; PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; NPAS4 regulates expression of target genes; Heme signaling; Formation of the beta-catenin:TCF transactivating complex; BMAL1:CLOCK,NPAS2 activates circadian gene expression; Transcriptional activation of mitochondrial biogenesis; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Cytoprotection by HMOX1; Activation of gene expression by SREBF (SREBP); NFE2L2 regulating anti-oxidant/detoxification enzymes; HATs acetylate histones; TP53 Regulates Transcription of Genes Involved in Cytochrome C Release; Nuclear events mediated by NFE2L2; NFE2L2 regulates pentose phosphate pathway genes; FOXO-mediated transcription of cell death genes; Regulation of FOXO transcriptional activity by acetylation; RORA activates gene expression; Attenuation phase; CD209 (DC-SIGN) signaling; Activation of the TFAP2 (AP-2) family of transcription factors; TRAF3-dependent IRF activation pathway; TRAF6 mediated IRF7 activation; Regulation of gene expression by Hypoxia-inducible Factor; RUNX1 regulates transcription of genes involved in differentiation of myeloid cells; LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production"	"64"	"0"	"49.0"	"64.0"	"45.1"	"44.0"	"40.9"	"43.1"	"56.8"	"96.7"	"103.3"	"217.6"	"331.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96DE5"	"Anaphase-promoting complex subunit 16 OS=Homo sapiens OX=9606 GN=ANAPC16 PE=1 SV=1"	"0.000"	""	"14"	"1"	"2"	"1"	"110"	"11.7"	"4.97"	"370.44"	"2.86"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf17256"	"119504"	"ENSG00000166295"	"ANAPC16"	"hsa:119504; Q96DE5"	""	"Separation of Sister Chromatids; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; CDK-mediated phosphorylation and removal of Cdc6; Autodegradation of Cdh1 by Cdh1:APC/C; Assembly of the pre-replicative complex; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of Cyclin B; Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase; Regulation of APC/C activators between G1/S and early anaphase; Phosphorylation of the APC/C; APC-Cdc20 mediated degradation of Nek2A; Senescence-Associated Secretory Phenotype (SASP); Transcriptional Regulation by VENTX; Aberrant regulation of mitotic exit in cancer due to RB1 defects"	"17"	"0"	"69.0"	"52.0"	"75.0"	"53.9"	"57.1"	"66.2"	"80.9"	"112.2"	"108.6"	"188.9"	"268.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P32121"	"Beta-arrestin-2 OS=Homo sapiens OX=9606 GN=ARRB2 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"409"	"46.1"	"7.69"	""	"2.85"	""	"1"	"cell-cell signaling;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00339, Pf02752"	"409"	"ENSG00000141480"	"ARRB2"	"B4DLW0; B5B0C0; B7WPL3; D3DTK2; H0Y688; hsa:409; P32121; Q0Z8D3; Q2PP19; Q6ICT3; Q8N7Y2; Q9UEQ6"	"Corticotropin-releasing hormone signaling pathway; Complement system; Myometrial relaxation and contraction pathways; Wnt signaling pathway; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Hedgehog signaling pathway; Gastrin signaling pathway; Kisspeptin/kisspeptin receptor system in the ovary; GPR143 in melanocytes and retinal pigment epithelium cells; Calcium regulation in cardiac cells"	"Ub-specific processing proteases; Activated NOTCH1 Transmits Signal to the Nucleus; Cargo recognition for clathrin-mediated endocytosis; Activation of SMO; G alpha (s) signalling events; Signaling by BRAF and RAF1 fusions; Thrombin signalling through proteinase activated receptors (PARs); WNT5A-dependent internalization of FZD4; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants"	"27"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UPN6"	"SR-related and CTD-associated factor 8 OS=Homo sapiens OX=9606 GN=SCAF8 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1271"	"140.4"	"8.29"	"243.46"	"2.85"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf04818"	"22828"	"ENSG00000213079"	"SCAF8"	"B7Z888; hsa:22828; Q5TBU6; Q6NSK3; Q9BQN8; Q9BX43; Q9UPN6"	""	""	"0"	"0"	"115.2"	"88.7"	"99.6"	"108.0"	"95.7"	"105.0"	"130.7"	"166.6"	"178.3"	"340.8"	"410.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UEG4"	"Zinc finger protein 629 OS=Homo sapiens OX=9606 GN=ZNF629 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"869"	"96.6"	"7.93"	"240.65"	"2.85"	"1"	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00096"	"23361"	"ENSG00000102870"	"ZNF629"	"hsa:23361; Q15938; Q9UEG4"	""	""	"0"	"0"	"11.7"	"12.9"	"13.5"	"10.8"	"14.4"	"10.9"	"15.6"	"17.9"	"20.5"	"30.2"	"41.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13526"	"Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 OS=Homo sapiens OX=9606 GN=PIN1 PE=1 SV=1"	"0.000"	""	"9"	"1"	"2"	"1"	"163"	"18.2"	"8.82"	"418.72"	"2.84"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00397, Pf00639"	"5300"	"ENSG00000127445"	"PIN1"	"A8K4V9; hsa:5300; Q13526; Q53X75"	"Novel intracellular components of RIG-I-like receptor pathway"	"Regulation of TP53 Activity through Phosphorylation; ISG15 antiviral mechanism; Negative regulators of DDX58/IFIH1 signaling; PI5P Regulates TP53 Acetylation; RHO GTPases Activate NADPH Oxidases"	"6"	"0"	"34.2"	"33.5"	"43.2"	"36.6"	"31.6"	"37.5"	"36.6"	"75.4"	"93.0"	"129.1"	"239.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H3Q1"	"Cdc42 effector protein 4 OS=Homo sapiens OX=9606 GN=CDC42EP4 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"356"	"38.0"	"5.19"	"300.39"	"2.84"	"1"	"1"	"cell organization and biogenesis;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00786, Pf14957"	"23580"	"ENSG00000179604"	"CDC42EP4"	"B3KUS7; hsa:23580; O95828; Q96FT3; Q9H3Q1"	""	"CDC42 GTPase cycle; RAC1 GTPase cycle; RAC2 GTPase cycle; RHOQ GTPase cycle"	"4"	"0"	"24.0"	"13.0"	"25.6"	"23.9"	"26.9"	"23.4"	"30.6"	"44.3"	"47.7"	"58.8"	"59.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6MZP7"	"Protein lin-54 homolog OS=Homo sapiens OX=9606 GN=LIN54 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"749"	"79.4"	"9.01"	"242.02"	"2.84"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03638"	"132660"	"ENSG00000189308"	"LIN54"	"hsa:132660; Q32M68; Q32M69; Q6MZP7; Q6N071; Q76B60"	"DYRK1A involvement regarding cell proliferation in brain development"	"G1/S-Specific Transcription; Polo-like kinase mediated events; Cyclin E associated events during G1/S transition ; Transcription of E2F targets under negative control by DREAM complex; Cyclin A:Cdk2-associated events at S phase entry; Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"	"8"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6RFH5"	"WD repeat-containing protein 74 OS=Homo sapiens OX=9606 GN=WDR74 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"385"	"42.4"	"8.32"	"376.15"	"2.83"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	""	"Pf00400"	"54663"	"ENSG00000133316"	"WDR74"	"A8K8G5; hsa:54663; Q6RFH5; Q9BRC9; Q9H6X8; Q9NVY2"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4X5"	"E3 ubiquitin-protein ligase ARIH1 OS=Homo sapiens OX=9606 GN=ARIH1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"557"	"64.1"	"5.08"	"269.33"	"2.83"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01485, Pf19422"	"25820"	"ENSG00000166233"	"ARIH1"	"B2R6U3; hsa:25820; O76026; Q9H3T6; Q9UEN0; Q9UP39; Q9Y4X5"	""	"ISG15 antiviral mechanism"	"1"	"0"	"9.2"	"5.6"	"8.9"	"7.5"	"6.8"	"10.2"	"12.2"	"24.3"	"30.8"	"78.1"	"93.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6X2"	"E3 SUMO-protein ligase PIAS3 OS=Homo sapiens OX=9606 GN=PIAS3 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"628"	"68.0"	"7.69"	"282.63"	"2.83"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf02891, Pf14324"	"10401"	"ENSG00000131788"	"PIAS3"	"hsa:10401; Q9UFI3; Q9Y6X2"	"Androgen receptor signaling pathway; Prolactin signaling pathway; Interleukin-11 signaling pathway; Oncostatin M signaling pathway; EGF/EGFR signaling pathway; Regulatory circuits of the STAT3 signaling pathway; Interactions between immune cells and microRNAs in tumor microenvironment; TAR syndrome; Interferon type I signaling pathways"	"SUMOylation of transcription cofactors; SUMOylation of DNA replication proteins; SUMOylation of intracellular receptors; SUMOylation of transcription factors; Formation of Incision Complex in GG-NER; SUMOylation of immune response proteins"	"15"	"0"	"61.3"	"46.3"	"59.1"	"59.9"	"50.5"	"52.5"	"86.1"	"114.5"	"158.0"	"269.2"	"414.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q7LBC6"	"Lysine-specific demethylase 3B OS=Homo sapiens OX=9606 GN=KDM3B PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1761"	"191.5"	"7.18"	""	"2.82"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02373"	"51780"	"ENSG00000120733"	"KDM3B"	"A6H8X7; hsa:51780; Q7LBC6; Q9BVH6; Q9BW93; Q9BZ52; Q9NYF4; Q9UPS0"	"Thermogenesis"	"HDMs demethylate histones"	"2"	"0"	"37.2"	"27.0"	"28.7"	"27.5"	"23.1"	"22.7"	"35.8"	"179.3"	"186.7"	"393.0"	"487.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13057"	"Bifunctional coenzyme A synthase OS=Homo sapiens OX=9606 GN=COASY PE=1 SV=4"	"0.000"	""	"2"	"1"	"2"	"1"	"564"	"62.3"	"6.99"	"295.19"	"2.82"	"1"	"1"	"other metabolic processes"	"other membranes;mitochondrion"	"kinase activity;other molecular function"	"Pf01121, Pf01467"	"80347"	"ENSG00000068120"	"COASY"	"B2RA78; B4DLU0; hsa:80347; Q13057; Q6GS23; Q8NBM7; Q8NEW1; Q8WXD4; Q9NRM3"	"Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway"	"Coenzyme A biosynthesis"	"2"	"0"	"5.1"	"0.0"	"5.5"	"3.0"	"2.4"	"3.7"	"5.9"	"14.9"	"11.2"	"71.5"	"79.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y296"	"Trafficking protein particle complex subunit 4 OS=Homo sapiens OX=9606 GN=TRAPPC4 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"219"	"24.3"	"6.21"	"252.81"	"2.82"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;developmental processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf04099"	"51399"	"ENSG00000196655; ENSG00000280495"	"TRAPPC4"	"A8K3A5; B4DME1; hsa:51399; Q9Y296"	""	"RAB GEFs exchange GTP for GDP on RABs; COPII-mediated vesicle transport; Syndecan interactions"	"3"	"0"	"6.1"	"7.3"	"7.7"	"13.0"	"10.6"	"10.0"	"14.5"	"26.9"	"28.3"	"80.0"	"115.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UL03"	"Integrator complex subunit 6 OS=Homo sapiens OX=9606 GN=INTS6 PE=1 SV=1"	"0.001"	""	"1"	"1"	"2"	"1"	"887"	"100.3"	"8.62"	"235.61"	"2.81"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus"	"other molecular function"	"Pf13519, Pf15300"	"26512"	"ENSG00000102786"	"INTS6"	"hsa:26512; Q0P664; Q6PJP4; Q9UFK0; Q9UL03; Q9Y5M9"	""	"RNA polymerase II transcribes snRNA genes"	"1"	"0"	"18.2"	"12.2"	"16.6"	"15.1"	"17.6"	"11.4"	"23.6"	"35.4"	"38.5"	"65.1"	"93.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H4X1"	"Regulator of cell cycle RGCC OS=Homo sapiens OX=9606 GN=RGCC PE=1 SV=1"	"0.000"	""	"8"	"1"	"2"	"1"	"137"	"14.6"	"4.75"	"237.65"	"2.81"	"1"	"1"	"cell cycle OR cell proliferation;stress response;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf15151"	"28984"	"ENSG00000102760"	"RGCC"	"hsa:28984; Q6NZ48; Q9H4X1; Q9UL69"	""	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"	"1"	"0"	"10.4"	"9.0"	"13.4"	"12.7"	"9.9"	"9.9"	"15.8"	"19.8"	"13.9"	"17.8"	"22.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O94806"	"Serine/threonine-protein kinase D3 OS=Homo sapiens OX=9606 GN=PRKD3 PE=1 SV=1"	""	""	"1"	"1"	"1"	"1"	"890"	"100.4"	"6.87"	""	"2.81"	""	"1"	"protein metabolism;other metabolic processes;signal transduction"	"other membranes;cytosol;nucleus"	"kinase activity;other molecular function"	"Pf00069, Pf00130, Pf00169"	"23683"	"ENSG00000115825"	"PRKD3"	"D6W587; hsa:23683; O94806; Q53TR7; Q8NEL8"	"G protein signaling pathways; Hippo signaling regulation pathways; Chronic hyperglycemia impairment of neuron function"	"Sphingolipid de novo biosynthesis"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q68CZ1"	"Protein fantom OS=Homo sapiens OX=9606 GN=RPGRIP1L PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1315"	"151.1"	"5.35"	"273.50"	"2.81"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding"	"Pf00168, Pf11618, Pf18111"	"23322"	"ENSG00000103494"	"RPGRIP1L"	"A0PJ88; hsa:23322; Q68CZ1; Q9Y2K8"	"Genes related to primary cilium development (based on CRISPR); Joubert syndrome; Ciliopathies; NPHP1 deletion syndrome"	"Anchoring of the basal body to the plasma membrane; Hedgehog 'off' state"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8TE54"	"Anion exchange transporter OS=Homo sapiens OX=9606 GN=SLC26A7 PE=2 SV=2"	""	""	"4"	"1"	"1"	"1"	"656"	"72.2"	"7.90"	""	"2.81"	""	"1"	"transport"	"plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	"transporter activity"	"Pf00916, Pf01740"	"115111"	"ENSG00000147606"	"SLC26A7"	"hsa:115111; Q24JS8; Q8TE53; Q8TE54; Q96RN2"	""	"Multifunctional anion exchangers"	"1"	"0"	"30.7"	"28.7"	"33.1"	"26.4"	"30.4"	"31.9"	"42.4"	"155.2"	"142.9"	"427.6"	"520.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14981"	"TATA-binding protein-associated factor 172 OS=Homo sapiens OX=9606 GN=BTAF1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1849"	"206.8"	"6.52"	"314.60"	"2.80"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf12054"	"9044"	"ENSG00000095564"	"BTAF1"	"B4E0W6; hsa:9044; O14981; O43578"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P17677"	"Neuromodulin OS=Homo sapiens OX=9606 GN=GAP43 PE=1 SV=1"	""	""	"8"	"1"	"1"	"1"	"238"	"24.8"	"4.72"	""	"2.80"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00612, Pf06614, Pf10580"	"2596"	"ENSG00000172020"	"GAP43"	"A8K0Y4; hsa:2596; P17677"	"Glial cell differentiation; Spinal cord injury"	"L1CAM interactions"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NWT1"	"p21-activated protein kinase-interacting protein 1 OS=Homo sapiens OX=9606 GN=PAK1IP1 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"392"	"43.9"	"8.91"	"297.69"	"2.79"	"1"	"1"	"cell cycle OR cell proliferation;other biological processes"	"nucleus"	""	"Pf00400"	"55003"	"ENSG00000111845; ENSG00000285226"	"PAK1IP1"	"hsa:55003; Q5T4J2; Q96QJ8; Q96T87; Q9NWT1"	""	""	"0"	"0"	"14.4"	"15.2"	"19.9"	"17.6"	"19.7"	"21.7"	"28.4"	"80.5"	"70.4"	"153.4"	"213.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IXK0"	"Polyhomeotic-like protein 2 OS=Homo sapiens OX=9606 GN=PHC2 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"858"	"90.7"	"8.69"	"264.62"	"2.79"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00536, Pf16616"	"1912"	"ENSG00000134686"	"PHC2"	"A1L4Q1; A8KA40; D3DPR2; hsa:1912; Q2TAL3; Q5T0C1; Q6NUJ6; Q6ZQR1; Q8IXK0; Q8N306; Q8TAG8; Q96BL4; Q9Y4Y7"	""	"Regulation of PTEN gene transcription; Oxidative Stress Induced Senescence; SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"	"8"	"0"	"95.2"	"88.4"	"109.8"	"90.6"	"103.1"	"88.2"	"114.2"	"155.7"	"133.5"	"252.4"	"282.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46379"	"Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1132"	"119.3"	"5.60"	"316.42"	"2.79"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;other membranes;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;translation activity;other molecular function"	"Pf00240, Pf12057"	"7917"	"ENSG00000096155; ENSG00000204463; ENSG00000227761; ENSG00000228760; ENSG00000229524; ENSG00000233348; ENSG00000234651"	"BAG6"	"A2ADJ7; A3KQ42; A3KQ44; A6NGY6; A6PWF7; B0UX84; B4DZ12; B4E3V4; E7EMZ4; F8VXY4; hsa:7917; O95874; P46379; Q5HYL9; Q5SQ35; Q5SQ36; Q5SQ37; Q5SQ41; Q5SRP8; Q5SRP9; Q5STC1; Q5STX1; Q5STX3; Q96SA6; Q9BCN4"	""	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"	"1"	"0"	"5.5"	"4.2"	"7.1"	"8.8"	"7.3"	"4.1"	"10.4"	"22.8"	"15.0"	"64.3"	"81.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9H977"	"WD repeat-containing protein 54 OS=Homo sapiens OX=9606 GN=WDR54 PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"334"	"35.9"	"6.20"	""	"2.79"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"other molecular function"	""	"84058"	"ENSG00000005448"	"WDR54"	"B9A049; D6W5I3; hsa:84058; Q53H85; Q86V45; Q9H977"	""	""	"0"	"0"	"92.0"	"18.4"	"153.3"	"98.8"	"98.4"	"102.9"	"167.4"	"396.3"	"457.5"	"1019.3"	"1054.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6PJG2"	"Mitotic deacetylase-associated SANT domain protein OS=Homo sapiens OX=9606 GN=MIDEAS PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1045"	"114.9"	"9.19"	"318.33"	"2.79"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01448"	"91748"	"ENSG00000156030"	"MIDEAS"	"hsa:91748; Q6PJG2; Q6PK13; Q6PK59; Q6ZS23"	""	""	"0"	"0"	"31.8"	"24.9"	"22.2"	"27.8"	"29.5"	"24.4"	"31.4"	"53.2"	"50.9"	"87.9"	"78.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IXB1"	"DnaJ homolog subfamily C member 10 OS=Homo sapiens OX=9606 GN=DNAJC10 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"793"	"91.0"	"7.18"	"389.49"	"2.79"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"ER/Golgi"	"other molecular function"	"Pf00085, Pf00226"	"54431"	"ENSG00000077232"	"DNAJC10"	"hsa:54431; Q17RJ6; Q3B7W8; Q4ZG06; Q53QT7; Q6UWZ6; Q86T61; Q8IXB1; Q8NC82; Q8TD87; Q96K38; Q96K44; Q96K54; Q9NSY6"	""	""	"0"	"0"	"139.6"	"89.5"	"115.5"	"120.6"	"114.0"	"121.4"	"159.8"	"190.6"	"184.3"	"259.6"	"352.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14156"	"Protein EFR3 homolog A OS=Homo sapiens OX=9606 GN=EFR3A PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"821"	"92.9"	"6.70"	"300.35"	"2.78"	"1"	"1"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol"	""	""	"23167"	"ENSG00000132294"	"EFR3A"	"A7MD19; hsa:23167; Q14156; Q2VPK2; Q63HL7; Q68DX1; Q6IQ18"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TAE8"	"Growth arrest and DNA damage-inducible proteins-interacting protein 1 OS=Homo sapiens OX=9606 GN=GADD45GIP1 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"222"	"25.4"	"10.02"	"305.42"	"2.78"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	""	"Pf10147"	"90480"	"ENSG00000179271"	"GADD45GIP1"	"hsa:90480; Q8IVM3; Q8TAE8; Q8TE51; Q969P9; Q9BSM6"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"38.5"	"24.7"	"32.2"	"41.9"	"31.8"	"44.8"	"56.8"	"87.1"	"87.1"	"109.5"	"150.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NVP2"	"Histone chaperone ASF1B OS=Homo sapiens OX=9606 GN=ASF1B PE=1 SV=1"	""	""	"10"	"1"	"1"	"1"	"202"	"22.4"	"4.56"	""	"2.78"	""	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf04729"	"55723"	"ENSG00000105011; ENSG00000288210"	"ASF1B"	"hsa:55723; Q53G51; Q9NVP2; Q9NVZ0"	""	""	"0"	"0"	"32.8"	"19.8"	"50.5"	"51.9"	"37.3"	"41.3"	"51.7"	"51.5"	"54.9"	"100.2"	"118.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96IJ6"	"Mannose-1-phosphate guanyltransferase alpha OS=Homo sapiens OX=9606 GN=GMPPA PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"420"	"46.3"	"7.21"	"356.59"	"2.77"	"1"	"1"	"other metabolic processes"	"other cell component"	"other molecular function"	"Pf00483"	"29926"	"ENSG00000144591"	"GMPPA"	"A6NJ74; A8K3Q6; B3KMT4; hsa:29926; Q53GI0; Q96IJ6; Q9NWC3; Q9Y5P5"	"N-glycan biosynthesis"	"Synthesis of GDP-mannose"	"2"	"0"	"22.5"	"17.0"	"22.0"	"24.1"	"20.8"	"17.4"	"28.1"	"58.9"	"54.2"	"157.6"	"244.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92616"	"eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6"	"0.000"	""	"1"	"3"	"4"	"3"	"2671"	"292.6"	"7.47"	"869.53"	"2.77"	"3"	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"35.7"	"31.3"	"28.4"	"30.7"	"30.2"	"27.4"	"35.9"	"78.2"	"88.3"	"156.0"	"164.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11441"	"Ubiquitin-like protein 4A OS=Homo sapiens OX=9606 GN=UBL4A PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"157"	"17.8"	"8.66"	"282.11"	"2.77"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00240, Pf17840"	"8266"	"ENSG00000102178"	"UBL4A"	"hsa:8266; P11441; Q5HY80"	""	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"	"1"	"0"	"64.5"	"54.6"	"104.9"	"80.4"	"63.6"	"73.6"	"95.6"	"129.4"	"153.2"	"342.0"	"473.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6K1"	"DNA (cytosine-5)-methyltransferase 3A OS=Homo sapiens OX=9606 GN=DNMT3A PE=1 SV=4"	"0.000"	""	"1"	"1"	"2"	"1"	"912"	"101.8"	"6.57"	"275.44"	"2.77"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00145, Pf00855, Pf17980"	"1788"	"ENSG00000119772"	"DNMT3A"	"E9PEB8; hsa:1788; Q86TE8; Q86XF5; Q8IZV0; Q8WXU9; Q9Y6K1"	"One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways; Hematopoietic stem cell gene regulation by GABP alpha/beta complex; MTHFR deficiency; Opioid receptor pathways"	"RMTs methylate histone arginines; PRC2 methylates histones and DNA; Defective pyroptosis; DNA methylation; SUMOylation of DNA methylation proteins"	"10"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P82930"	"28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"218"	"25.6"	"9.98"	"306.60"	"2.77"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf16053"	"65993"	"ENSG00000074071"	"MRPS34"	"hsa:65993; P82930; Q9BVI7"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"128.5"	"100.6"	"137.9"	"113.0"	"119.7"	"125.1"	"163.1"	"218.8"	"204.7"	"385.4"	"563.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95835"	"Serine/threonine-protein kinase LATS1 OS=Homo sapiens OX=9606 GN=LATS1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1130"	"126.8"	"8.70"	"289.16"	"2.77"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00627"	"9113"	"ENSG00000131023"	"LATS1"	"hsa:9113; O95835; Q6PKD0"	"Mesodermal commitment pathway; Transcription co-factors SKI and SKIL protein partners; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-YAP signaling; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; Leukocyte-intrinsic Hippo pathway functions; Pleural mesothelioma"	"Signaling by Hippo"	"9"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q06203"	"Amidophosphoribosyltransferase OS=Homo sapiens OX=9606 GN=PPAT PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"517"	"57.4"	"6.76"	""	"2.76"	""	"1"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf00156, Pf13522"	"5471"	"ENSG00000128059"	"PPAT"	"hsa:5471; Q06203"	"Fluoropyrimidine activity; Metabolic reprogramming in colon cancer"	"Purine ribonucleoside monophosphate biosynthesis"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75446"	"Histone deacetylase complex subunit SAP30 OS=Homo sapiens OX=9606 GN=SAP30 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"220"	"23.3"	"9.17"	"263.87"	"2.76"	"1"	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf13866, Pf13867"	"8819"	"ENSG00000164105"	"SAP30"	"D3DP38; hsa:8819; O75446"	"Retinoblastoma gene in cancer; Notch signaling pathway"	"Potential therapeutics for SARS; HDACs deacetylate histones; NoRC negatively regulates rRNA expression"	"5"	"0"	"5.8"	"9.1"	"5.2"	"6.6"	"4.4"	"6.4"	"8.5"	"25.7"	"29.7"	"101.8"	"184.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4F1"	"FERM, ARHGEF and pleckstrin domain-containing protein 1 OS=Homo sapiens OX=9606 GN=FARP1 PE=1 SV=1"	"0.000"	""	"2"	"2"	"3"	"2"	"1045"	"118.6"	"8.15"	"581.25"	"2.76"	"2"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00169, Pf00373, Pf00621, Pf08736, Pf09379, Pf09380"	"10160"	"ENSG00000152767"	"FARP1"	"hsa:10160; Q5JVI9; Q6IQ29; Q9Y4F1"	""	"RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOF GTPase cycle"	"4"	"0"	"182.0"	"124.0"	"164.0"	"166.0"	"157.6"	"166.6"	"209.9"	"247.7"	"250.1"	"432.0"	"510.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05026"	"Sodium/potassium-transporting ATPase subunit beta-1 OS=Homo sapiens OX=9606 GN=ATP1B1 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"303"	"35.0"	"8.53"	"271.22"	"2.76"	"1"	"1"	"cell adhesion;cell organization and biogenesis;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"transporter activity;other molecular function"	"Pf00287"	"481"	"ENSG00000143153"	"ATP1B1"	"hsa:481; P05026; Q5TGZ3"	"Proximal tubule transport; Calcium regulation in cardiac cells"	"Potential therapeutics for SARS; Ion homeostasis; Ion transport by P-type ATPases; Basigin interactions"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13137"	"Calcium-binding and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=CALCOCO2 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"446"	"52.2"	"5.02"	"239.82"	"2.76"	"1"	"1"	"other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf17751"	"10241"	"ENSG00000136436"	"CALCOCO2"	"B2RBT0; B4DDC4; B4DDT4; B4DP36; B4E0C0; E7ENK0; E7ETP5; E9PBE5; hsa:10241; Q13137; Q53FQ5; Q53HB5; Q6IBN9; Q9BTF7"	""	""	"0"	"0"	"17.2"	"18.0"	"18.6"	"18.1"	"18.3"	"17.4"	"18.5"	"37.4"	"38.4"	"78.7"	"102.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q562F6"	"Shugoshin 2 OS=Homo sapiens OX=9606 GN=SGO2 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1265"	"144.7"	"7.91"	""	"2.76"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	""	""	"151246"	"ENSG00000163535"	"SGO2"	"hsa:151246; Q53RR9; Q53T20; Q562F6; Q86XY4; Q8IWK2; Q8IZK1; Q8N1Q5; Q96LQ3"	"Cohesin complex - Cornelia de Lange syndrome"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"7"	"0"	"5.8"	"7.5"	"8.8"	"6.8"	"5.6"	"7.5"	"12.0"	"20.8"	"17.8"	"26.0"	"25.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H981"	"Actin-related protein 8 OS=Homo sapiens OX=9606 GN=ACTR8 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"624"	"70.4"	"7.78"	"492.62"	"2.75"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus"	"other molecular function"	"Pf00022"	"93973"	"ENSG00000113812"	"ACTR8"	"B3KSW7; hsa:93973; Q8N566; Q9H663; Q9H981"	""	"UCH proteinases; DNA Damage Recognition in GG-NER"	"2"	"0"	"5.2"	"3.6"	"4.7"	"3.1"	"5.2"	"6.7"	"7.7"	"17.0"	"18.2"	"52.1"	"75.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EY4"	"Translation machinery-associated protein 16 OS=Homo sapiens OX=9606 GN=TMA16 PE=1 SV=2"	"0.000"	""	"5"	"1"	"2"	"1"	"203"	"23.8"	"9.26"	"376.43"	"2.75"	"1"	"1"	"other biological processes"	"nucleus"	"other molecular function"	"Pf11176"	"55319"	"ENSG00000198498"	"TMA16"	"hsa:55319; Q0P6E4; Q0P6J1; Q96EY4; Q9NUR7"	""	""	"0"	"0"	"148.5"	"91.4"	"146.4"	"148.7"	"142.1"	"153.5"	"205.9"	"177.8"	"171.3"	"240.0"	"252.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"A4D1P6"	"WD repeat-containing protein 91 OS=Homo sapiens OX=9606 GN=WDR91 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"747"	"83.3"	"6.58"	""	"2.75"	""	"1"	"transport;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle"	"enzyme regulator activity"	"Pf00400"	"29062"	"ENSG00000105875"	"WDR91"	"A4D1P6; A6NK54; C9JMI4; hsa:29062; Q6FI65; Q6MZQ1; Q6P4I1; Q96AE5; Q96G63; Q9H062; Q9H9B6; Q9NVG7; Q9NZY6"	""	"CDC42 GTPase cycle"	"1"	"0"	"4.2"	"7.3"	"4.7"	"3.5"	"5.4"	"3.6"	"10.1"	"13.4"	"14.5"	"23.5"	"36.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14578"	"Citron Rho-interacting kinase OS=Homo sapiens OX=9606 GN=CIT PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"2027"	"231.3"	"6.57"	"270.25"	"2.75"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069, Pf00169, Pf00780"	"11113"	"ENSG00000122966"	"CIT"	"hsa:11113; O14578; Q2M5E1; Q6XUH8; Q86UQ9; Q9UPZ7"	"Pleural mesothelioma; G13 signaling pathway"	"RHOC GTPase cycle; RHOA GTPase cycle; RAC1 GTPase cycle; RHOB GTPase cycle; RHO GTPases activate CIT"	"7"	"0"	"5.7"	"6.0"	"8.3"	"6.2"	"6.9"	"12.8"	"7.0"	"24.1"	"19.6"	"55.1"	"62.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30044"	"Peroxiredoxin-5, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX5 PE=1 SV=4"	"0.000"	""	"4"	"1"	"2"	"1"	"214"	"22.1"	"8.70"	"369.37"	"2.75"	"1"	"1"	"other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf08534"	"25824"	"ENSG00000126432"	"PRDX5"	"A6NC19; A6NG06; B7ZLJ4; B7ZVW3; hsa:25824; P30044; Q14CK0; Q6IAF2; Q9UBU5; Q9UJU4; Q9UKX4"	"Selenium micronutrient network"	""	"1"	"0"	"124.4"	"102.3"	"148.0"	"134.5"	"114.8"	"91.6"	"133.6"	"177.9"	"172.3"	"285.4"	"399.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P0P8"	"Mitochondrial transcription rescue factor 1 OS=Homo sapiens OX=9606 GN=MTRES1 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"240"	"27.9"	"9.29"	"313.89"	"2.74"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"mitochondrion"	"translation activity;nucleic acid binding activity"	""	"51250"	"ENSG00000130349"	"MTRES1"	"B3KRG9; hsa:51250; Q9P0P8"	""	""	"0"	"0"	"8.5"	"9.9"	"10.3"	"11.8"	"8.6"	"6.5"	"14.1"	"67.4"	"75.1"	"162.2"	"146.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P18031"	"Tyrosine-protein phosphatase non-receptor type 1 OS=Homo sapiens OX=9606 GN=PTPN1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"435"	"49.9"	"6.27"	"250.85"	"2.74"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"other membranes;cytosol;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00102"	"5770"	"ENSG00000196396"	"PTPN1"	"hsa:5770; P18031; Q5TGD8; Q9BQV9; Q9NQQ4"	"Leptin signaling pathway; Prolactin signaling pathway; Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4); VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Insulin signaling"	"Insulin receptor recycling; Growth hormone receptor signaling; Regulation of IFNG signaling; Regulation of IFNA/IFNB signaling; Negative regulation of MET activity; Integrin signaling; MECP2 regulates neuronal receptors and channels; PTK6 Down-Regulation"	"14"	"0"	"0.0"	"2.1"	"0.0"	"0.0"	"0.0"	"0.0"	"1.6"	"9.2"	"9.4"	"40.9"	"59.6"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NRV9"	"Heme-binding protein 1 OS=Homo sapiens OX=9606 GN=HEBP1 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"189"	"21.1"	"5.80"	"348.14"	"2.74"	"1"	"1"	"other biological processes"	"non-structural extracellular;other cell component"	"other molecular function"	"Pf04832"	"50865"	"ENSG00000013583"	"HEBP1"	"A8K1G2; hsa:50865; Q9NRV9; Q9Y5Z5"	""	"G alpha (i) signalling events; Formyl peptide receptors bind formyl peptides and many other ligands"	"2"	"0"	"82.5"	"78.8"	"88.1"	"102.1"	"106.9"	"90.4"	"107.2"	"151.6"	"140.5"	"222.6"	"280.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30041"	"Peroxiredoxin-6 OS=Homo sapiens OX=9606 GN=PRDX6 PE=1 SV=3"	"0.000"	""	"5"	"1"	"2"	"1"	"224"	"25.0"	"6.38"	"397.99"	"2.74"	"1"	"1"	"other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00578, Pf10417"	"9588"	"ENSG00000117592"	"PRDX6"	"A8JZY7; hsa:9588; P30041; P32077; Q5TAH4; Q5ZEZ8"	"Nuclear receptors meta-pathway; NRF2 pathway; VEGFA-VEGFR2 signaling"	"Neutrophil degranulation; Detoxification of Reactive Oxygen Species"	"5"	"0"	"56.5"	"31.7"	"65.5"	"64.7"	"46.0"	"42.8"	"57.5"	"109.7"	"103.5"	"203.5"	"412.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96FJ2"	"Dynein light chain 2, cytoplasmic OS=Homo sapiens OX=9606 GN=DYNLL2 PE=1 SV=1"	"0.000"	""	"8"	"1"	"2"	"1"	"89"	"10.3"	"7.37"	"286.49"	"2.74"	"1"	"1"	"other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf01221"	"140735"	"ENSG00000264364"	"DYNLL2"	"B2R5B4; hsa:140735; Q96FJ2"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein; 3q29 copy number variation syndrome"	"Separation of Sister Chromatids; MHC class II antigen presentation; Aggrephagy; HCMV Early Events; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; COPI-mediated anterograde transport; Intraflagellar transport; COPI-independent Golgi-to-ER retrograde traffic; Macroautophagy; Activation of BMF and translocation to mitochondria"	"18"	"0"	"163.8"	"175.9"	"152.8"	"218.9"	"190.0"	"196.0"	"240.2"	"356.8"	"282.0"	"396.7"	"517.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P33981"	"Dual specificity protein kinase TTK OS=Homo sapiens OX=9606 GN=TTK PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"857"	"97.0"	"8.16"	"437.94"	"2.73"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"7272"	"ENSG00000112742"	"TTK"	"A8K8U5; B2RDW2; E1P543; hsa:7272; P33981; Q15272; Q5TCS0; Q9BW51; Q9NTM0"	"Cell cycle; Retinoblastoma gene in cancer"	""	"2"	"0"	"20.0"	"13.4"	"22.0"	"22.5"	"16.3"	"18.3"	"25.8"	"61.7"	"73.4"	"211.6"	"335.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14676"	"Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3"	"0.000"	""	"0"	"1"	"2"	"1"	"2089"	"226.5"	"5.47"	"346.39"	"2.73"	"1"	"1"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	""	"Pf00498, Pf16770"	"9656"	"ENSG00000137337; ENSG00000206481; ENSG00000224587; ENSG00000225589; ENSG00000228575; ENSG00000231135; ENSG00000234012; ENSG00000237095"	"MDC1"	"A2AB04; A2BF04; A2RRA8; A7YY86; B0S8A2; hsa:9656; Q0EFC2; Q14676; Q2L6H7; Q2TAZ4; Q5JP55; Q5JP56; Q5ST83; Q68CQ3; Q86Z06; Q96QC2"	"ATM signaling in development and disease ; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; NIPBL role in DNA damage - Cornelia de Lange syndrome"	"Processing of DNA double-strand break ends; SUMOylation of DNA damage response and repair proteins; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; TP53 Regulates Transcription of DNA Repair Genes; G2/M DNA damage checkpoint; Nonhomologous End-Joining (NHEJ)"	"9"	"0"	"85.4"	"58.0"	"87.5"	"71.7"	"78.6"	"63.0"	"84.4"	"151.0"	"118.9"	"451.8"	"612.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00423"	"Echinoderm microtubule-associated protein-like 1 OS=Homo sapiens OX=9606 GN=EML1 PE=1 SV=3"	"0.000"	""	"2"	"2"	"3"	"2"	"815"	"89.8"	"7.06"	"609.89"	"2.73"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400, Pf03451"	"2009"	"ENSG00000066629"	"EML1"	"hsa:2009; O00423; Q86U15; Q8N536; Q8N5C4; Q8WWL6"	""	""	"0"	"0"	"118.6"	"92.2"	"100.9"	"102.6"	"97.6"	"100.6"	"120.8"	"212.2"	"189.7"	"465.8"	"606.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P34947"	"G protein-coupled receptor kinase 5 OS=Homo sapiens OX=9606 GN=GRK5 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"590"	"67.7"	"8.10"	"284.52"	"2.72"	"1"	"1"	"cell-cell signaling;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00615"	"2869"	"ENSG00000198873"	"GRK5"	"D3DRD0; hsa:2869; P34947; Q5T059"	"Myometrial relaxation and contraction pathways; Chemokine signaling pathway; Comprehensive IL-17A signaling; Calcium regulation in cardiac cells"	"G alpha (q) signalling events; G alpha (s) signalling events"	"6"	"0"	"50.9"	"40.1"	"50.6"	"42.5"	"49.2"	"50.5"	"83.0"	"142.0"	"147.8"	"310.9"	"389.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60563"	"Cyclin-T1 OS=Homo sapiens OX=9606 GN=CCNT1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"726"	"80.6"	"8.78"	"326.50"	"2.72"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00134"	"904"	"ENSG00000129315"	"CCNT1"	"A9XU13; E7EX76; hsa:904; O60563; O60581"	"Initiation of transcription and translation elongation at the HIV-1 LTR; Male infertility"	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; Estrogen-dependent gene expression; Interactions of Tat with host cellular proteins"	"17"	"0"	"85.4"	"68.4"	"92.2"	"86.3"	"81.3"	"89.0"	"105.3"	"127.9"	"123.4"	"234.1"	"247.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96GG9"	"DCN1-like protein 1 OS=Homo sapiens OX=9606 GN=DCUN1D1 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"259"	"30.1"	"5.34"	"237.65"	"2.72"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf03556, Pf14555"	"54165"	"ENSG00000043093"	"DCUN1D1"	"B2RB37; hsa:54165; Q7L3G9; Q8TEX7; Q96GG9; Q9H6M1; Q9HCT3"	""	"Neddylation"	"1"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"2.5"	"0.0"	"0.0"	"7.1"	"5.1"	"44.1"	"59.9"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O43639"	"Cytoplasmic protein NCK2 OS=Homo sapiens OX=9606 GN=NCK2 PE=1 SV=2"	""	""	"6"	"1"	"1"	"1"	"380"	"42.9"	"6.95"	""	"2.72"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00017, Pf00018, Pf14604"	"8440"	"ENSG00000071051"	"NCK2"	"D3DVK1; hsa:8440; O43639; Q9BWN9; Q9UIC3"	"Pathogenic Escherichia coli infection; Brain-derived neurotrophic factor (BDNF) signaling pathway; EGF/EGFR signaling pathway; Genes controlling nephrogenesis; ErbB signaling pathway"	"RHOV GTPase cycle; RHOU GTPase cycle; Nephrin family interactions; Downstream signal transduction; VEGFA-VEGFR2 Pathway; Ephrin signaling; Activation of RAC1; Regulation of cortical dendrite branching"	"13"	"0"	"3.8"	"3.3"	"8.0"	"5.6"	"4.4"	"4.9"	"6.6"	"17.7"	"16.0"	"66.4"	"101.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P82663"	"28S ribosomal protein S25, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS25 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"173"	"20.1"	"8.82"	"282.30"	"2.72"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf05047"	"64432"	"ENSG00000131368"	"MRPS25"	"B4DFJ5; B4DQG6; hsa:64432; P82663; Q9H7P5"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IWJ2"	"GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4"	"0.000"	""	"1"	"1"	"2"	"1"	"1684"	"195.8"	"5.14"	"264.58"	"2.72"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"cytosol;ER/Golgi;nucleus"	"other molecular function"	"Pf01465, Pf16704"	"9648"	"ENSG00000135968"	"GCC2"	"A6H8X8; hsa:9648; O15045; Q4ZG46; Q8IWJ2; Q8TDH3; Q9H2G8"	"Deregulation of Rab and Rab effector genes in bladder cancer"	"Signaling by ALK fusions and activated point mutants; Retrograde transport at the Trans-Golgi-Network"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q14457"	"Beclin-1 OS=Homo sapiens OX=9606 GN=BECN1 PE=1 SV=2"	""	""	"4"	"1"	"1"	"1"	"450"	"51.9"	"4.89"	""	"2.71"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"other membranes;cytosol;mitochondrion;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf04111, Pf15285, Pf17675"	"8678"	"ENSG00000126581"	"BECN1"	"B2R6N7; hsa:8678; O75595; Q14457; Q9UNA8"	"Alzheimer's disease and miRNA effects; Nanoparticle triggered autophagic cell death; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Autophagy; 7q11.23 copy number variation syndrome; Pleural mesothelioma; Alzheimer's disease; Clock-controlled autophagy in bone metabolism; Autophagy in pancreatic ductal adenocarcinoma"	"Ub-specific processing proteases; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Macroautophagy; Translation of Replicase and Assembly of the Replication Transcription Complex; Translation of Replicase and Assembly of the Replication Transcription Complex"	"15"	"0"	"23.1"	"17.2"	"200.4"	"74.7"	"77.8"	"46.0"	"59.6"	"136.7"	"303.8"	"228.6"	"150.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q7L1Q6"	"Basic leucine zipper and W2 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=BZW1 PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"419"	"48.0"	"5.92"	""	"2.71"	""	"1"	"other biological processes"	"other cell component"	""	"Pf02020"	"9689"	"ENSG00000082153"	"BZW1"	"B4DLZ8; B4DWF7; hsa:9689; Q14281; Q15394; Q7L1Q6; Q9BUY0"	""	""	"0"	"0"	"18.0"	"18.1"	"20.4"	"19.3"	"19.7"	"15.4"	"24.8"	"88.3"	"70.6"	"517.9"	"1160.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46937"	"Transcriptional coactivator YAP1 OS=Homo sapiens OX=9606 GN=YAP1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"504"	"54.4"	"5.17"	"337.35"	"2.71"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00397"	"10413"	"ENSG00000137693"	"YAP1"	"B4DTY1; B7ZA01; E3WEB5; E3WEB6; E9PRV2; F5H202; hsa:10413; K0KQ18; K0KYZ8; K0L195; K0L1G3; P46937; Q7Z574; Q8IUY9"	"Mesodermal commitment pathway; Mesodermal commitment pathway; RAC1/PAK1/p38/MMP2 pathway; miR-509-3p alteration of YAP1/ECM axis; Ciliary landscape; Leukocyte-intrinsic Hippo pathway functions; Netrin-UNC5B signaling pathway; Galanin receptor pathway; Pleural mesothelioma"	"Signaling by Hippo; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Formation of axial mesoderm; Nuclear signaling by ERBB4; RUNX2 regulates osteoblast differentiation; YAP1- and WWTR1 (TAZ)-stimulated gene expression; EGR2 and SOX10-mediated initiation of Schwann cell myelination; RUNX3 regulates YAP1-mediated transcription"	"17"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UGU0"	"Transcription factor 20 OS=Homo sapiens OX=9606 GN=TCF20 PE=1 SV=3"	"0.000"	""	"0"	"1"	"2"	"1"	"1960"	"211.6"	"9.04"	"335.36"	"2.71"	"1"	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf13771"	"6942"	"ENSG00000100207; ENSG00000262024; ENSG00000276461; ENSG00000280467; ENSG00000281897; ENSG00000282892; ENSG00000283026; ENSG00000283681"	"TCF20"	"A9JX12; hsa:6942; O14528; Q13078; Q4V353; Q9H4M0; Q9UGU0"	"Matrix metalloproteinases"	""	"1"	"0"	"66.4"	"52.4"	"65.2"	"64.4"	"65.5"	"73.6"	"73.3"	"126.2"	"125.2"	"242.4"	"316.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49755"	"Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"219"	"25.0"	"7.44"	"358.51"	"2.71"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"transporter activity;other molecular function"	"Pf01105"	"10972"	"ENSG00000170348"	"TMED10"	"B2R605; hsa:10972; P49755; Q15602; Q16536; Q86TC2; Q86TS5"	"mRNA processing; 5q35 copy number variation"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport; COPII-mediated vesicle transport; Cargo concentration in the ER"	"6"	"0"	"42.1"	"27.4"	"48.9"	"43.9"	"40.1"	"35.4"	"49.4"	"166.7"	"229.4"	"878.8"	"1301.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z569"	"BRCA1-associated protein OS=Homo sapiens OX=9606 GN=BRAP PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"592"	"67.3"	"5.92"	"282.07"	"2.71"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02148, Pf07576, Pf13639"	"8315"	"ENSG00000089234"	"BRAP"	"B4DRM1; B9EGS8; hsa:8315; O43238; O75341; Q7Z569"	"Ras signaling"	"RAF activation; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Negative regulation of MAPK pathway"	"6"	"0"	"20.0"	"20.8"	"21.1"	"19.4"	"22.6"	"16.9"	"33.7"	"59.2"	"56.4"	"123.3"	"107.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12830"	"Nucleosome-remodeling factor subunit BPTF OS=Homo sapiens OX=9606 GN=BPTF PE=1 SV=3"	"0.000"	""	"0"	"1"	"2"	"1"	"3046"	"338.1"	"6.54"	"286.57"	"2.70"	"1"	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00439, Pf00628, Pf02791, Pf15613"	"2186"	"ENSG00000171634"	"BPTF"	"hsa:2186; Q12830; Q6NX67; Q7Z7D6; Q9UIG2"	"Endoderm differentiation; 16p11.2 proximal deletion syndrome"	""	"2"	"0"	"85.5"	"76.3"	"91.3"	"95.5"	"81.5"	"91.3"	"120.0"	"188.7"	"182.6"	"406.8"	"534.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H9T3"	"Elongator complex protein 3 OS=Homo sapiens OX=9606 GN=ELP3 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"547"	"62.2"	"8.88"	"353.42"	"2.70"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00583, Pf04055, Pf16199"	"55140"	"ENSG00000134014"	"ELP3"	"B4DE19; B4DIG1; E2QRI5; hsa:55140; Q53G84; Q6AWB0; Q9BVF7; Q9H9T3; Q9NVZ1"	"Ethanol effects on histone modifications"	"HATs acetylate histones"	"2"	"0"	"41.8"	"28.3"	"31.8"	"29.7"	"30.6"	"24.6"	"41.0"	"78.8"	"72.3"	"343.5"	"673.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P53004"	"Biliverdin reductase A OS=Homo sapiens OX=9606 GN=BLVRA PE=1 SV=2"	""	""	"8"	"1"	"1"	"1"	"296"	"33.4"	"6.44"	""	"2.69"	""	"1"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf01408, Pf09166"	"644"	"ENSG00000106605"	"BLVRA"	"A8K747; hsa:644; O95019; P53004; Q86UX0; Q96QL4; Q9BRW8"	"IL-10 anti-inflammatory signaling pathway"	"Cytoprotection by HMOX1; Heme degradation"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14641"	"Segment polarity protein dishevelled homolog DVL-2 OS=Homo sapiens OX=9606 GN=DVL2 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"736"	"78.9"	"6.02"	"320.66"	"2.69"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00595, Pf00610, Pf00778, Pf02377, Pf12316"	"1856"	"ENSG00000004975"	"DVL2"	"D3DTN3; hsa:1856; O14641; Q53XM0"	"Alzheimer's disease and miRNA effects; Neural crest differentiation; Notch signaling; Wnt signaling pathway; Regulation of Wnt / B-catenin signaling by small molecule compounds; Embryonic stem cell pluripotency pathways; Wnt signaling pathway and pluripotency; Wnt signaling in kidney disease; Type 2 papillary renal cell carcinoma; lncRNA in canonical Wnt signaling and colorectal cancer; Breast cancer pathway; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Pleural mesothelioma; Alzheimer's disease; DNA damage response (only ATM dependent)"	"RHO GTPases Activate Formins; Asymmetric localization of PCP proteins; Degradation of DVL; Cargo recognition for clathrin-mediated endocytosis; WNT mediated activation of DVL; Disassembly of the destruction complex and recruitment of AXIN to the membrane; Negative regulation of TCF-dependent signaling by DVL-interacting proteins; WNT5:FZD7-mediated leishmania damping; Signaling by Hippo; WNT5A-dependent internalization of FZD4"	"29"	"0"	"197.1"	"134.2"	"203.0"	"179.2"	"174.5"	"179.4"	"204.2"	"240.6"	"253.8"	"356.6"	"414.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96L58"	"Beta-1,3-galactosyltransferase 6 OS=Homo sapiens OX=9606 GN=B3GALT6 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"329"	"37.1"	"9.66"	"339.54"	"2.69"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf01762"	"126792"	"ENSG00000176022"	"B3GALT6"	"hsa:126792; Q5T7M5; Q96L58"	"Proteoglycan biosynthesis; 1p36 copy number variation syndrome; Glycosaminoglycan synthesis in fibroblasts"	"A tetrasaccharide linker sequence is required for GAG synthesis; Defective B3GALT6 causes EDSP2 and SEMDJL1"	"5"	"0"	"4.5"	"8.1"	"7.2"	"4.6"	"6.9"	"5.0"	"9.8"	"13.2"	"15.0"	"38.0"	"44.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NB49"	"Phospholipid-transporting ATPase IG OS=Homo sapiens OX=9606 GN=ATP11C PE=1 SV=3"	"0.000"	""	"2"	"2"	"3"	"2"	"1132"	"129.4"	"6.67"	"565.00"	"2.69"	"2"	"1"	"cell organization and biogenesis;transport"	"plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf00122, Pf13246, Pf16209, Pf16212"	"286410"	"ENSG00000101974"	"ATP11C"	"hsa:286410; Q5JT69; Q5JT70; Q5JT71; Q5JT72; Q5JT73; Q6ZND5; Q6ZU50; Q6ZUP7; Q70IJ9; Q70IK0; Q8NB49; Q8WX24"	"Complement system in neuronal development and plasticity"	"Ion transport by P-type ATPases"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00268"	"Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1085"	"110.0"	"9.94"	"353.17"	"2.69"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf05236, Pf07531"	"6874"	"ENSG00000130699"	"TAF4"	"A6NGD9; hsa:6874; O00268; Q5TBP6; Q99721; Q9BR40; Q9BX42"	""	"RNA Polymerase II Pre-transcription Events; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; Regulation of TP53 Activity through Phosphorylation; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation"	"9"	"0"	"25.2"	"16.8"	"17.6"	"24.6"	"23.4"	"22.4"	"25.9"	"40.6"	"35.3"	"72.6"	"85.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q4LE39"	"AT-rich interactive domain-containing protein 4B OS=Homo sapiens OX=9606 GN=ARID4B PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1312"	"147.7"	"5.12"	"248.68"	"2.69"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;mitochondrion;nucleus"	"nucleic acid binding activity"	"Pf01388, Pf08169, Pf11717"	"51742"	"ENSG00000054267"	"ARID4B"	"A1L465; hsa:51742; Q3MHV4; Q4LE39; Q5HY99; Q5T2C2; Q5T2C3; Q5T2C4; Q5T2C5; Q5T2C6; Q6P600; Q86UX1; Q86WR4; Q9H915; Q9NYU3; Q9NZB6; Q9NZG4; Q9P2W4; Q9UF62; Q9Y6E1"	"Pathways affected in adenoid cystic carcinoma"	"Potential therapeutics for SARS; HDACs deacetylate histones; NoRC negatively regulates rRNA expression"	"4"	"0"	"14.3"	"13.6"	"7.9"	"8.6"	"9.2"	"7.2"	"16.4"	"21.0"	"15.3"	"27.2"	"51.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q4VC05"	"B-cell CLL/lymphoma 7 protein family member A OS=Homo sapiens OX=9606 GN=BCL7A PE=1 SV=1"	"0.000"	""	"5"	"2"	"3"	"2"	"210"	"22.8"	"5.14"	"734.26"	"2.69"	"2"	"1"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	""	"Pf04714"	"605"	"ENSG00000110987; ENSG00000282873"	"BCL7A"	"B4DJN6; B7ZB21; hsa:605; Q13843; Q14CT7; Q4VC05"	""	""	"0"	"0"	"167.4"	"115.7"	"159.6"	"153.4"	"148.1"	"290.9"	"410.4"	"457.4"	"432.7"	"848.2"	"1227.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14497"	"AT-rich interactive domain-containing protein 1A OS=Homo sapiens OX=9606 GN=ARID1A PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"2285"	"241.9"	"6.70"	"313.67"	"2.69"	"1"	"1"	"cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01388, Pf12031"	"8289"	"ENSG00000117713"	"ARID1A"	"D3DPL1; hsa:8289; O14497; Q53FK9; Q5T0W1; Q5T0W2; Q5T0W3; Q8NFD6; Q96T89; Q9BY33; Q9HBJ5; Q9UPZ1"	"Androgen receptor network in prostate cancer; Pathways affected in adenoid cystic carcinoma; Tumor suppressor activity of SMARCB1; Thermogenesis; Kleefstra syndrome"	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; RMTs methylate histone arginines"	"7"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O00154"	"Cytosolic acyl coenzyme A thioester hydrolase OS=Homo sapiens OX=9606 GN=ACOT7 PE=1 SV=3"	""	""	"3"	"1"	"1"	"1"	"380"	"41.8"	"8.54"	""	"2.69"	""	"1"	"other metabolic processes"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf03061"	"11332"	"ENSG00000097021"	"ACOT7"	"A8K0K7; A8K232; A8K6B8; A8K837; B3KQ12; hsa:11332; O00154; O43703; Q53Y78; Q5JYL2; Q5JYL3; Q5JYL4; Q5JYL5; Q5JYL6; Q5TGR4; Q9UJM9; Q9Y539; Q9Y540"	""	"Mitochondrial Fatty Acid Beta-Oxidation"	"1"	"0"	"13.2"	"8.7"	"10.9"	"11.0"	"10.4"	"9.5"	"11.3"	"26.1"	"37.2"	"125.6"	"436.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q06265"	"Exosome complex component RRP45 OS=Homo sapiens OX=9606 GN=EXOSC9 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"439"	"48.9"	"5.29"	"295.78"	"2.68"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01138, Pf03725"	"5393"	"ENSG00000123737"	"EXOSC9"	"hsa:5393; Q06265; Q12883; Q4W5P5; Q86Y41; Q86Y48"	"Ciliary landscape"	"Major pathway of rRNA processing in the nucleolus and cytosol; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	"7"	"0"	"7.9"	"6.9"	"19.5"	"10.2"	"10.6"	"16.2"	"18.6"	"34.2"	"37.6"	"119.1"	"208.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A8MWD9"	"Putative small nuclear ribonucleoprotein G-like protein 15 OS=Homo sapiens OX=9606 GN=SNRPGP15 PE=5 SV=2"	"0.000"	""	"9"	"1"	"2"	"1"	"76"	"8.5"	"8.84"	"245.97"	"2.68"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf01423"	""	""	"SNRPGP15"	"A8MWD9"	""	""	"0"	"0"	"182.7"	"149.6"	"207.3"	"197.9"	"183.6"	"165.5"	"227.3"	"323.8"	"302.3"	"618.1"	"976.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q13625"	"Apoptosis-stimulating of p53 protein 2 OS=Homo sapiens OX=9606 GN=TP53BP2 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1128"	"125.5"	"6.07"	""	"2.68"	""	"1"	"cell cycle OR cell proliferation;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00018, Pf00023"	"7159"	"ENSG00000143514"	"TP53BP2"	"B4DG66; hsa:7159; Q12892; Q13625; Q86X75; Q96KQ3"	""	"TP53 Regulates Transcription of Death Receptors and Ligands; Activation of PUMA and translocation to mitochondria; TP53 Regulates Transcription of Genes Involved in Cytochrome C Release; TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain; Regulation of TP53 Activity through Association with Co-factors"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96GD4"	"Aurora kinase B OS=Homo sapiens OX=9606 GN=AURKB PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"344"	"39.3"	"9.29"	"238.07"	"2.68"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"9212"	"ENSG00000178999"	"AURKB"	"B4DNM4; C7G533; C7G534; C7G535; D3DTR4; hsa:9212; J9JID1; O14630; O60446; O95083; Q96DV5; Q96GD4; Q9UQ46"	"Microtubule cytoskeleton regulation; ATM signaling in development and disease"	"RHO GTPases Activate Formins; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; EML4 and NUDC in mitotic spindle formation; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Regulation of MECP2 expression and activity; SUMOylation of DNA replication proteins; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Regulation of TP53 Activity through Phosphorylation"	"12"	"0"	"48.4"	"28.7"	"76.5"	"57.3"	"66.3"	"54.9"	"74.4"	"85.6"	"86.8"	"140.3"	"196.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IX90"	"Spindle and kinetochore-associated protein 3 OS=Homo sapiens OX=9606 GN=SKA3 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"412"	"46.3"	"5.11"	"264.93"	"2.68"	"1"	"1"	"cell cycle OR cell proliferation;other biological processes"	"cytosol;cytoskeleton;other cell component"	""	""	"221150"	"ENSG00000165480"	"SKA3"	"A2A330; A2A331; B2RBY2; hsa:221150; Q5VZV5; Q86WR2; Q8IX90; Q8NBG1; Q96D22"	""	""	"0"	"0"	"13.2"	"10.0"	"13.1"	"12.0"	"4.7"	"8.5"	"15.9"	"18.8"	"22.2"	"35.4"	"38.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H7Z3"	"Nuclear exosome regulator NRDE2 OS=Homo sapiens OX=9606 GN=NRDE2 PE=1 SV=3"	"0.000"	""	"2"	"2"	"3"	"2"	"1164"	"132.6"	"7.68"	"615.35"	"2.67"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus"	""	"Pf08424"	"55051"	"ENSG00000119720"	"NRDE2"	"B4DH71; hsa:55051; Q4G0A7; Q9H7Z3; Q9NWH6"	""	""	"0"	"0"	"155.5"	"115.7"	"143.3"	"147.4"	"134.2"	"148.1"	"183.7"	"411.8"	"420.8"	"575.6"	"551.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43615"	"Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"452"	"51.3"	"8.32"	"297.49"	"2.67"	"1"	"1"	"cell organization and biogenesis;transport"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf04280"	"10469"	"ENSG00000104980"	"TIMM44"	"A8K0R9; D6W664; hsa:10469; O43615; Q8N193"	""	"Mitochondrial protein import"	"1"	"0"	"12.6"	"7.9"	"13.3"	"12.7"	"7.0"	"14.0"	"16.1"	"34.5"	"34.6"	"99.5"	"131.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P41594"	"Metabotropic glutamate receptor 5 OS=Homo sapiens OX=9606 GN=GRM5 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1212"	"132.4"	"7.78"	""	"2.67"	""	"1"	"cell-cell signaling;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00003, Pf01094, Pf07562, Pf10606"	"2915"	"ENSG00000168959"	"GRM5"	"hsa:2915; P41594; Q6J164"	"Common pathways underlying drug addiction; Fragile X syndrome; Vitamin D-sensitive calcium signaling in depression; GPCRs, class C metabotropic glutamate, pheromone; Neuroinflammation and glutamatergic signaling; 15q25 copy number variation"	"G alpha (q) signalling events; Class C/3 (Metabotropic glutamate/pheromone receptors); Neurexins and neuroligins"	"9"	"0"	"338.2"	"249.2"	"290.6"	"263.1"	"277.8"	"288.5"	"377.9"	"487.4"	"380.7"	"603.2"	"965.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96JC1"	"Vam6/Vps39-like protein OS=Homo sapiens OX=9606 GN=VPS39 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"886"	"101.7"	"6.99"	"262.75"	"2.66"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;other cytoplasmic organelle;other cell component"	""	"Pf00780, Pf10366, Pf10367"	"23339"	"ENSG00000166887"	"VPS39"	"hsa:23339; O94869; Q71SQ6; Q7Z3V3; Q96B93; Q96JC1; Q96RM0"	"VEGFA-VEGFR2 signaling; Ebola virus infection in host; Perturbations to host-cell autophagy, induced by SARS-CoV-2 proteins"	"SARS-CoV-2 modulates autophagy"	"4"	"0"	"4.7"	"3.7"	"6.0"	"5.7"	"3.8"	"5.2"	"6.4"	"16.6"	"12.0"	"32.6"	"40.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"A6NED2"	"RCC1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RCCD1 PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"376"	"40.1"	"5.27"	""	"2.66"	""	"1"	"cell organization and biogenesis"	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf00415"	"91433"	"ENSG00000166965"	"RCCD1"	"A6NED2; B2RTP9; hsa:91433; Q29RX6"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8TDJ6"	"DmX-like protein 2 OS=Homo sapiens OX=9606 GN=DMXL2 PE=1 SV=2"	""	""	"0"	"1"	"1"	"1"	"3036"	"339.4"	"6.38"	""	"2.66"	""	"1"	"other biological processes"	"other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf00400, Pf12234"	"23312"	"ENSG00000104093"	"DMXL2"	"B2RTR3; B7ZMH3; F5GWF1; hsa:23312; O94938; Q8TDJ6"	""	""	"0"	"0"	"143.0"	"43.6"	"224.5"	"150.8"	"161.4"	"168.5"	"188.1"	"209.6"	"241.4"	"409.1"	"377.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P53990"	"IST1 homolog OS=Homo sapiens OX=9606 GN=IST1 PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"364"	"39.7"	"5.35"	""	"2.66"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf03398"	"9798"	"ENSG00000182149"	"IST1"	"A8KAH5; hsa:9798; J3QLU7; P53990; Q3SYM4; Q9BQ81; Q9BWN2"	""	"Neutrophil degranulation; Sealing of the nuclear envelope (NE) by ESCRT-III"	"2"	"0"	"73.8"	"66.2"	"83.3"	"74.0"	"69.0"	"60.0"	"92.5"	"319.9"	"353.2"	"1520.2"	"1879.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q99442"	"Translocation protein SEC62 OS=Homo sapiens OX=9606 GN=SEC62 PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"399"	"45.8"	"7.12"	""	"2.66"	""	"1"	"transport"	"other membranes;ER/Golgi"	"other molecular function"	"Pf03839"	"7095"	"ENSG00000008952"	"SEC62"	"D3DNQ0; hsa:7095; O00682; O00729; Q99442"	""	""	"0"	"0"	"60.0"	"53.9"	"54.6"	"61.2"	"52.8"	"55.9"	"63.2"	"111.2"	"90.0"	"202.3"	"273.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00429"	"Dynamin-1-like protein OS=Homo sapiens OX=9606 GN=DNM1L PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"736"	"81.8"	"6.81"	"325.58"	"2.66"	"1"	"1"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00350, Pf01031, Pf02212"	"10059"	"ENSG00000087470"	"DNM1L"	"A8K4X9; B4DGC9; B4DSU8; G8JLD5; hsa:10059; J3KPI2; O00429; O14541; O60709; Q59GN9; Q7L6B3; Q8TBT7; Q9BWM1; Q9Y5J2"	"Synaptic vesicle pathway; CAMKK2 pathway"	"Apoptotic execution phase"	"3"	"0"	"70.7"	"48.7"	"65.9"	"69.5"	"65.7"	"60.6"	"72.0"	"141.5"	"153.0"	"719.1"	"1148.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UJ04"	"Testis-specific Y-encoded-like protein 4 OS=Homo sapiens OX=9606 GN=TSPYL4 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"414"	"45.1"	"8.57"	""	"2.65"	""	"1"	"cell organization and biogenesis"	"nucleus;other cell component"	"other molecular function"	"Pf00956"	"23270"	"ENSG00000187189"	"TSPYL4"	"B4DYQ2; hsa:23270; O94828; Q96GW8; Q9UJ04"	""	""	"0"	"0"	"20.6"	"14.2"	"15.1"	"17.1"	"13.8"	"17.6"	"17.4"	"23.4"	"16.2"	"22.2"	"29.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8ND56"	"Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3"	"0.000"	""	"4"	"2"	"3"	"1"	"463"	"50.5"	"9.52"	"572.62"	"2.65"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;signal transduction;other biological processes"	"cytosol;cytoskeleton;other cell component"	"nucleic acid binding activity"	"Pf09532, Pf12701"	"26065"	"ENSG00000257103; ENSG00000262860"	"LSM14A"	"B4DTG6; hsa:26065; Q76LX7; Q8ND56; Q96AR3; Q96K73; Q96SN5; Q9UFR3"	""	""	"0"	"0"	"69.3"	"65.1"	"81.6"	"83.7"	"79.8"	"76.9"	"89.0"	"90.0"	"88.4"	"150.8"	"181.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P0DPB6"	"DNA-directed RNA polymerases I and III subunit RPAC2 OS=Homo sapiens OX=9606 GN=POLR1D PE=1 SV=1"	"0.000"	""	"8"	"1"	"2"	"1"	"133"	"15.2"	"5.80"	"348.35"	"2.65"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf13656"	"51082"	"ENSG00000186184"	"POLR1D"	"hsa:51082; P0DPB6; Q5TBX2; Q96BR3; Q9Y2S0"	"Pyrimidine metabolism; Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	""	"4"	"0"	"43.1"	"46.9"	"35.7"	"36.1"	"33.0"	"39.5"	"47.9"	"94.3"	"116.8"	"292.2"	"424.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVC6"	"Mediator of RNA polymerase II transcription subunit 17 OS=Homo sapiens OX=9606 GN=MED17 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"651"	"72.8"	"7.44"	"293.07"	"2.64"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf10156"	"9440"	"ENSG00000042429"	"MED17"	"B3KN07; hsa:9440; Q9HA81; Q9NVC6; Q9UNP7; Q9Y2W0; Q9Y660"	""	"PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; Generic Transcription Pathway"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96QT6"	"PHD finger protein 12 OS=Homo sapiens OX=9606 GN=PHF12 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1004"	"109.6"	"7.74"	"319.07"	"2.64"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00628, Pf16737"	"57649"	"ENSG00000109118"	"PHF12"	"hsa:57649; Q0VAI5; Q2TAK2; Q6ZML2; Q96QT6; Q9BV34; Q9H7U9; Q9P205"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42766"	"60S ribosomal protein L35 OS=Homo sapiens OX=9606 GN=RPL35 PE=1 SV=2"	"0.000"	""	"15"	"2"	"3"	"1"	"123"	"14.5"	"11.05"	"717.06"	"2.64"	"2"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00831"	"11224"	"ENSG00000136942"	"RPL35"	"A8K4V7; hsa:11224; P42766; Q4VBY5; Q5JTN5; Q6IBC7; Q96QJ7; Q9BYF4"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"57.6"	"49.0"	"60.4"	"51.1"	"53.5"	"62.3"	"94.5"	"128.8"	"149.5"	"294.2"	"434.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2I1"	"Nischarin OS=Homo sapiens OX=9606 GN=NISCH PE=1 SV=3"	"0.000"	""	"3"	"3"	"3"	"3"	"1504"	"166.5"	"5.14"	"498.30"	"2.64"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00787"	"11188"	"ENSG00000010322"	"NISCH"	"C9J245; hsa:11188; Q6PGP3; Q6PIB4; Q7L8M3; Q7Z2X6; Q9UES6; Q9UEU4; Q9UFW3; Q9Y2I1"	""	"RND3 GTPase cycle; RAC1 GTPase cycle; RND2 GTPase cycle"	"3"	"0"	"159.1"	"124.8"	"156.4"	"151.8"	"138.7"	"139.6"	"190.7"	"358.3"	"334.4"	"954.9"	"1289.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WXW3"	"Progesterone-induced-blocking factor 1 OS=Homo sapiens OX=9606 GN=PIBF1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"757"	"89.8"	"6.02"	"292.54"	"2.64"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding"	""	"10464"	"ENSG00000083535"	"PIBF1"	"hsa:10464; O95664; Q6U9V2; Q6UG50; Q86V07; Q8WXW3; Q96SF4"	"Genes related to primary cilium development (based on CRISPR); Joubert syndrome; Ciliopathies"	""	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96IV0"	"Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase OS=Homo sapiens OX=9606 GN=NGLY1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"654"	"74.3"	"6.89"	"247.99"	"2.64"	"1"	"1"	"protein metabolism;other metabolic processes;stress response"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01841, Pf04721, Pf09409"	"55768"	"ENSG00000151092"	"NGLY1"	"B4DJE9; hsa:55768; Q59FB1; Q6PJD8; Q96IV0; Q9BVR8; Q9NR70"	""	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"	"1"	"0"	"14.3"	"5.3"	"15.6"	"8.4"	"5.9"	"10.6"	"7.2"	"12.5"	"11.4"	"35.7"	"33.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BRT9"	"DNA replication complex GINS protein SLD5 OS=Homo sapiens OX=9606 GN=GINS4 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"223"	"26.0"	"4.98"	"264.98"	"2.64"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	""	"Pf05916, Pf16922"	"84296"	"ENSG00000147536"	"GINS4"	"B2R8H5; D3DSY0; hsa:84296; Q8N648; Q9BRT9"	""	"Unwinding of DNA"	"1"	"0"	"5.7"	"4.1"	"6.9"	"5.1"	"8.7"	"7.4"	"9.1"	"12.0"	"10.7"	"21.6"	"27.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07311"	"Acylphosphatase-1 OS=Homo sapiens OX=9606 GN=ACYP1 PE=1 SV=2"	"0.000"	""	"10"	"1"	"2"	"1"	"99"	"11.3"	"9.31"	"269.77"	"2.63"	"1"	"1"	"other metabolic processes"	""	"other molecular function"	"Pf00708"	"97"	"ENSG00000119640"	"ACYP1"	"A6NDV8; B2R590; hsa:97; P07311"	""	""	"0"	"0"	"16.4"	"15.4"	"13.4"	"12.2"	"18.8"	"22.7"	"33.6"	"118.2"	"126.8"	"241.7"	"289.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NZ63"	"Telomere length and silencing protein 1 homolog OS=Homo sapiens OX=9606 GN=C9orf78 PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"289"	"33.7"	"6.74"	""	"2.63"	""	"1"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf07052"	"51759"	"ENSG00000136819"	"C9orf78"	"B3KPX8; hsa:51759; Q8WVU6; Q9NT39; Q9NZ63"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"9.6"	"10.4"	"14.0"	"13.6"	"13.6"	"16.0"	"13.8"	"27.0"	"31.4"	"78.5"	"132.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P26885"	"Peptidyl-prolyl cis-trans isomerase FKBP2 OS=Homo sapiens OX=9606 GN=FKBP2 PE=1 SV=2"	"0.000"	""	"13"	"2"	"3"	"2"	"142"	"15.6"	"9.13"	"686.31"	"2.63"	"2"	"1"	"protein metabolism;other metabolic processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf00254"	"2286"	"ENSG00000173486"	"FKBP2"	"hsa:2286; P26885; Q5BJH9; Q9BTS7"	"Complement system"	""	"1"	"0"	"81.7"	"76.9"	"97.5"	"94.9"	"86.4"	"95.8"	"129.1"	"517.4"	"503.3"	"1454.4"	"1402.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NEM7"	"Transcription factor SPT20 homolog OS=Homo sapiens OX=9606 GN=SUPT20H PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"779"	"85.7"	"8.48"	"309.43"	"2.63"	"1"	"1"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf12090"	"55578"	"ENSG00000102710"	"SUPT20H"	"E7ER46; hsa:55578; Q71RF3; Q8NEM7; Q9Y6A6"	""	"HATs acetylate histones"	"1"	"0"	"62.0"	"49.1"	"66.1"	"54.6"	"54.5"	"59.5"	"67.6"	"136.7"	"146.6"	"345.9"	"444.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9C0D5"	"Protein TANC1 OS=Homo sapiens OX=9606 GN=TANC1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1861"	"202.1"	"8.32"	"326.00"	"2.63"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"other cell component"	""	"Pf00023, Pf12796"	"85461"	"ENSG00000115183"	"TANC1"	"C9JD88; hsa:85461; Q49AI8; Q9C0D5"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95363"	"Phenylalanine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=FARS2 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"451"	"52.3"	"7.46"	"281.75"	"2.63"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01409, Pf03147"	"10667"	"ENSG00000145982"	"FARS2"	"B2R664; hsa:10667; O95363; Q53F66; Q5TCS3; Q6FG29; Q9NPY7; Q9P062"	""	"Mitochondrial tRNA aminoacylation"	"1"	"0"	"7.6"	"6.5"	"4.8"	"3.9"	"7.1"	"8.7"	"5.4"	"18.9"	"19.9"	"37.4"	"47.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IWA4"	"Mitofusin-1 OS=Homo sapiens OX=9606 GN=MFN1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"741"	"84.1"	"6.33"	"245.53"	"2.63"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf00350, Pf04799"	"55669"	"ENSG00000171109"	"MFN1"	"A0A0C4DFN1; B2RAR1; D3DNR6; hsa:55669; O15323; O60639; Q8IWA4; Q9BZB5; Q9NWQ2"	""	"Factors involved in megakaryocyte development and platelet production; PINK1-PRKN Mediated Mitophagy; RHOT2 GTPase cycle"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q86U86"	"Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1"	""	""	"1"	"1"	"1"	"1"	"1689"	"192.8"	"6.89"	""	"2.62"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00439, Pf00505, Pf01426"	"55193"	"ENSG00000163939"	"PBRM1"	"A1L381; A1L382; A4FUJ7; hsa:55193; Q1RMD1; Q1RMD2; Q86U86; Q96MS2; Q9H2T3; Q9H2T4; Q9H2T5; Q9H301; Q9H314"	"Clear cell renal cell carcinoma pathways"	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; RMTs methylate histone arginines"	"3"	"0"	"7.7"	"7.4"	"11.0"	"12.5"	"9.9"	"9.8"	"15.4"	"29.7"	"24.1"	"57.2"	"70.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBW7"	"Zinc finger MYM-type protein 2 OS=Homo sapiens OX=9606 GN=ZMYM2 PE=1 SV=1"	"0.001"	""	"1"	"1"	"2"	"1"	"1377"	"154.8"	"6.34"	"235.29"	"2.62"	"1"	"1"	"other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf06467, Pf12012"	"7750"	"ENSG00000121741"	"ZMYM2"	"A6NDG0; A6NI02; hsa:7750; O43212; O43434; O60898; Q5W0Q4; Q5W0T3; Q63HP0; Q8NE39; Q9H0V5; Q9H538; Q9UBW7; Q9UEU2"	""	"Signaling by cytosolic FGFR1 fusion mutants; Signaling by FGFR1 in disease; Signaling by FLT3 fusion proteins"	"3"	"0"	"4.8"	"4.4"	"4.6"	"4.6"	"4.8"	"6.7"	"6.7"	"10.6"	"12.2"	"21.9"	"31.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A6NKF1"	"SAC3 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SAC3D1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"404"	"43.5"	"8.69"	"342.14"	"2.60"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;nucleus;other cell component"	""	"Pf03399"	""	""	"SAC3D1"	"A6NKF1; A8MX08; Q99773"	""	""	"0"	"0"	"28.2"	"18.8"	"25.8"	"27.7"	"17.3"	"17.5"	"30.4"	"73.7"	"68.4"	"201.3"	"324.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96DX7"	"Tripartite motif-containing protein 44 OS=Homo sapiens OX=9606 GN=TRIM44 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"344"	"38.4"	"4.21"	"317.49"	"2.60"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other cell component"	"other molecular function"	"Pf00643"	"54765"	"ENSG00000166326"	"TRIM44"	"D3DR14; hsa:54765; Q96DX7; Q96QY2; Q9UGK0"	""	""	"0"	"0"	"6.3"	"6.9"	"2.9"	"5.5"	"3.9"	"4.6"	"10.3"	"11.9"	"15.6"	"37.2"	"42.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BW61"	"DET1- and DDB1-associated protein 1 OS=Homo sapiens OX=9606 GN=DDA1 PE=1 SV=1"	"0.000"	""	"12"	"1"	"2"	"1"	"102"	"11.8"	"8.68"	"244.61"	"2.60"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf10172"	"79016"	"ENSG00000130311"	"DDA1"	"hsa:79016; Q9BW61"	""	"Neddylation"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9BYC9"	"39S ribosomal protein L20, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL20 PE=1 SV=1"	""	""	"7"	"1"	"1"	"1"	"149"	"17.4"	"10.86"	""	"2.60"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00453"	"55052"	"ENSG00000242485"	"MRPL20"	"B2RE41; B7Z746; hsa:55052; Q9BYC9"	"1p36 copy number variation syndrome"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"L0R819"	"ASNSD1 upstream open reading frame protein OS=Homo sapiens OX=9606 GN=ASDURF PE=1 SV=1"	"0.000"	""	"8"	"1"	"2"	"1"	"96"	"11.2"	"8.88"	"350.56"	"2.60"	"1"	"1"	"other biological processes"	"other cell component"	""	""	""	"ENSG00000286053"	"ASDURF"	"L0R819"	""	""	"0"	"0"	"47.0"	"30.3"	"45.5"	"44.5"	"36.2"	"45.1"	"58.1"	"170.4"	"190.7"	"562.3"	"719.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H814"	"Phosphorylated adapter RNA export protein OS=Homo sapiens OX=9606 GN=PHAX PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"394"	"44.4"	"5.40"	"280.67"	"2.60"	"1"	"1"	"transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf10258"	"51808"	"ENSG00000164902"	"PHAX"	"hsa:51808; Q9H814; Q9H8W1"	""	"RNA polymerase II transcribes snRNA genes; snRNP Assembly"	"2"	"0"	"18.9"	"11.4"	"13.2"	"12.6"	"13.3"	"19.6"	"23.6"	"22.1"	"22.5"	"37.0"	"43.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6J0"	"Calcineurin-binding protein cabin-1 OS=Homo sapiens OX=9606 GN=CABIN1 PE=1 SV=1"	"0.000"	""	"1"	"2"	"3"	"2"	"2220"	"246.2"	"6.02"	"469.88"	"2.60"	"2"	"1"	"cell organization and biogenesis;signal transduction"	"cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf09047"	"23523"	"ENSG00000099991"	"CABIN1"	"G5E9F3; hsa:23523; Q6PHY0; Q9Y460; Q9Y6J0"	""	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"	"1"	"0"	"47.6"	"36.6"	"39.5"	"44.8"	"37.9"	"31.5"	"47.2"	"117.9"	"112.5"	"366.6"	"543.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UHV9"	"Prefoldin subunit 2 OS=Homo sapiens OX=9606 GN=PFDN2 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"154"	"16.6"	"6.58"	"329.52"	"2.59"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01920"	"5202"	"ENSG00000143256"	"PFDN2"	"hsa:5202; Q9P0P7; Q9UHV9; Q9UN05"	"Cellular proteostasis"	"Prefoldin mediated transfer of substrate  to CCT/TriC"	"2"	"0"	"39.2"	"17.3"	"42.3"	"33.4"	"32.0"	"34.3"	"61.7"	"149.0"	"166.1"	"532.6"	"765.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q4KWH8"	"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 OS=Homo sapiens OX=9606 GN=PLCH1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1693"	"189.1"	"7.74"	"358.41"	"2.59"	"1"	"1"	"other metabolic processes;transport;signal transduction"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00168, Pf00387, Pf00388, Pf09279"	"23007"	"ENSG00000114805"	"PLCH1"	"hsa:23007; Q29RV9; Q4KWH8; Q4KWH9; Q68CN0; Q86XK4; Q9H9U2; Q9UPT3"	"Mesodermal commitment pathway; GPR40 pathway"	"Synthesis of IP3 and IP4 in the cytosol"	"3"	"0"	"21.7"	"9.8"	"16.6"	"15.5"	"17.2"	"14.8"	"17.8"	"22.3"	"21.3"	"27.6"	"51.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z4H7"	"HAUS augmin-like complex subunit 6 OS=Homo sapiens OX=9606 GN=HAUS6 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"955"	"108.6"	"6.47"	"240.46"	"2.59"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton"	"cytoskeletal activity"	"Pf14661"	"54801"	"ENSG00000147874"	"HAUS6"	"B3KPK4; B4DX82; hsa:54801; Q05CG1; Q14CB6; Q14CD9; Q2TA91; Q6IQ10; Q6NZX5; Q7Z4H7; Q8IZQ4; Q96FN0; Q9H950; Q9H998; Q9HCJ8; Q9NXT8"	""	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"7"	"0"	"7.2"	"6.2"	"9.7"	"9.5"	"8.2"	"2.7"	"7.0"	"21.9"	"13.0"	"42.7"	"60.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P29372"	"DNA-3-methyladenine glycosylase OS=Homo sapiens OX=9606 GN=MPG PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"298"	"32.8"	"9.57"	"244.09"	"2.59"	"1"	"1"	"DNA metabolism;other metabolic processes;stress response"	"cytosol;mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf02245"	"4350"	"ENSG00000103152"	"MPG"	"G5E9E2; hsa:4350; P29372; Q13770; Q15275; Q15961; Q5J9I4; Q96BZ6; Q96S33; Q9NNX5"	"Base excision repair; DNA repair pathways, full network"	"Recognition and association of DNA glycosylase with site containing an affected purine; Cleavage of the damaged purine; Displacement of DNA glycosylase by APEX1"	"5"	"0"	"35.9"	"35.7"	"53.1"	"50.3"	"41.2"	"41.2"	"57.5"	"83.6"	"91.3"	"182.5"	"225.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P82933"	"28S ribosomal protein S9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS9 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"396"	"45.8"	"9.51"	"236.98"	"2.58"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf00380"	"64965"	"ENSG00000135972"	"MRPS9"	"hsa:64965; P82933; Q6PG40"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"86.0"	"63.0"	"89.7"	"81.8"	"86.7"	"96.5"	"103.7"	"161.9"	"177.6"	"270.3"	"366.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q567U6"	"Coiled-coil domain-containing protein 93 OS=Homo sapiens OX=9606 GN=CCDC93 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"631"	"73.2"	"8.15"	"305.57"	"2.58"	"1"	"1"	"transport"	"other cytoplasmic organelle;other cell component"	""	"Pf09762"	"54520"	"ENSG00000125633"	"CCDC93"	"A8K3V7; hsa:54520; Q4LE78; Q53TJ2; Q567U6; Q8TBX5; Q9H6R5; Q9NV15"	""	""	"0"	"0"	"42.1"	"41.7"	"42.8"	"48.4"	"48.0"	"45.9"	"62.1"	"61.2"	"52.0"	"98.3"	"130.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96G01"	"Protein bicaudal D homolog 1 OS=Homo sapiens OX=9606 GN=BICD1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"975"	"110.7"	"5.81"	"348.90"	"2.58"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf09730"	"636"	"ENSG00000151746"	"BICD1"	"A8K2C3; F8W113; hsa:636; O43892; O43893; Q96G01"	""	"COPI-independent Golgi-to-ER retrograde traffic"	"1"	"0"	"5.4"	"3.4"	"7.9"	"6.4"	"4.0"	"4.9"	"4.1"	"18.4"	"19.8"	"65.9"	"97.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62877"	"E3 ubiquitin-protein ligase RBX1 OS=Homo sapiens OX=9606 GN=RBX1 PE=1 SV=1"	"0.000"	""	"13"	"1"	"2"	"1"	"108"	"12.3"	"6.96"	"246.02"	"2.58"	"1"	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf12678"	"9978"	"ENSG00000100387"	"RBX1"	"B2RDY1; hsa:9978; P62877; Q8N6Z8; Q9D1S2; Q9WUK9; Q9Y254"	"Cell cycle; Dual hijack model of Vif in HIV infection; Type 2 papillary renal cell carcinoma; NRF2-ARE regulation; Hippo-Merlin signaling dysregulation; 22q11.2 copy number variation syndrome; Nucleotide excision repair; Hijack of ubiquitination by SARS-CoV-2; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; 1p36 copy number variation syndrome"	"Potential therapeutics for SARS; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; Dual Incision in GG-NER; Regulation of expression of SLITs and ROBOs; Antigen processing: Ubiquitination & Proteasome degradation; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Degradation of DVL; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; Orc1 removal from chromatin; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Neddylation; Interleukin-1 signaling; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Regulation of BACH1 activity; NOTCH1 Intracellular Domain Regulates Transcription; Formation of TC-NER Pre-Incision Complex; Prolactin receptor signaling; DNA Damage Recognition in GG-NER; Nuclear events stimulated by ALK signaling in cancer; Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling"	"46"	"0"	"43.4"	"39.4"	"46.0"	"44.1"	"45.9"	"45.9"	"55.8"	"122.7"	"120.8"	"272.9"	"430.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P31930"	"Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"480"	"52.6"	"6.37"	"292.88"	"2.57"	"1"	"1"	"other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00675, Pf05193"	"7384"	"ENSG00000010256"	"UQCRC1"	"B2R7R8; hsa:7384; P31930; Q96DD2"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex III assembly"	"Respiratory electron transport"	"4"	"0"	"13.0"	"8.4"	"9.6"	"14.3"	"10.1"	"9.4"	"11.8"	"26.9"	"16.6"	"39.8"	"62.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q2M3C7"	"A-kinase anchor protein SPHKAP OS=Homo sapiens OX=9606 GN=SPHKAP PE=1 SV=1"	""	""	"0"	"1"	"1"	"1"	"1700"	"186.3"	"5.14"	""	"2.57"	""	"1"	""	"mitochondrion;other cell component"	"other molecular function"	"Pf05716"	"80309"	"ENSG00000153820"	"SPHKAP"	"hsa:80309; Q2M3C7; Q68DA3; Q68DR8; Q9C0I5"	""	""	"0"	"0"	"72.0"	"46.0"	"79.0"	"70.6"	"67.5"	"76.7"	"81.7"	"172.4"	"157.6"	"302.8"	"315.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P56545"	"C-terminal-binding protein 2 OS=Homo sapiens OX=9606 GN=CTBP2 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"445"	"48.9"	"6.95"	"357.24"	"2.56"	"1"	"1"	"cell-cell signaling;cell organization and biogenesis;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00389, Pf02826"	"1488"	"ENSG00000175029"	"CTBP2"	"A8K2X5; D3DRF5; hsa:1488; O43449; P56545; Q5SQP7; Q69YI3; Q86SV0; Q8IY44; Q9H2T8"	"Neural crest differentiation; Notch signaling; Mesodermal commitment pathway; Wnt signaling pathway and pluripotency; lncRNA in canonical Wnt signaling and colorectal cancer; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Ciliary landscape; Pleural mesothelioma"	"Repression of WNT target genes; Signaling by TCF7L2 mutants"	"11"	"0"	"135.3"	"72.6"	"125.3"	"111.4"	"104.0"	"115.3"	"139.6"	"223.9"	"218.5"	"494.8"	"661.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2G0"	"Protein EFR3 homolog B OS=Homo sapiens OX=9606 GN=EFR3B PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"817"	"92.4"	"6.70"	"250.44"	"2.56"	"1"	"1"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton"	""	""	"22979"	"ENSG00000084710"	"EFR3B"	"B7WPL8; hsa:22979; Q86XU6; Q9Y2G0"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P16219"	"Short-chain specific acyl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ACADS PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"412"	"44.3"	"7.99"	"311.93"	"2.56"	"1"	"1"	"other metabolic processes"	"cytoskeleton;mitochondrion;nucleus"	"other molecular function"	"Pf00441, Pf02770, Pf02771"	"35"	"ENSG00000122971"	"ACADS"	"hsa:35; P16219; P78331"	"Fatty acid beta-oxidation; Mitochondrial long chain fatty acid beta-oxidation; IL-18 signaling pathway; Mitochondrial fatty acid oxidation disorders"	"Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of butanoyl-CoA to acetyl-CoA"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46459"	"Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"744"	"82.5"	"6.95"	"237.09"	"2.56"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00004, Pf02359, Pf02933, Pf17862"	"4905"	"ENSG00000073969; ENSG00000276262; ENSG00000278174"	"NSF"	"A8K2D9; B4DFA2; hsa:4905; P46459; Q8N6D7; Q9UKZ2"	"Synaptic vesicle pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport; Intra-Golgi traffic; COPII-mediated vesicle transport; Retrograde transport at the Trans-Golgi-Network; Trafficking of GluR2-containing AMPA receptors"	"8"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NE86"	"Calcium uniporter protein, mitochondrial OS=Homo sapiens OX=9606 GN=MCU PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"351"	"39.8"	"8.65"	"311.17"	"2.56"	"1"	"1"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf04678"	"90550"	"ENSG00000156026"	"MCU"	"B2RDF3; B3KXV7; hsa:90550; Q8NE86; Q96FL3"	"Alzheimer's disease and miRNA effects; Pleural mesothelioma; Alzheimer's disease"	"Processing of SMDT1"	"5"	"0"	"21.6"	"11.1"	"18.2"	"14.6"	"18.7"	"11.9"	"20.5"	"31.1"	"34.3"	"57.8"	"72.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q10472"	"Polypeptide N-acetylgalactosaminyltransferase 1 OS=Homo sapiens OX=9606 GN=GALNT1 PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"559"	"64.2"	"7.72"	""	"2.56"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf00535, Pf00652"	"2589"	"ENSG00000141429"	"GALNT1"	"hsa:2589; Q10472; Q86TJ7; Q9UM86"	"Metabolism of sphingolipids in ER and Golgi apparatus"	"COPI-independent Golgi-to-ER retrograde traffic; O-linked glycosylation of mucins; Maturation of protein 3a; Maturation of protein 3a"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6WKZ4"	"Rab11 family-interacting protein 1 OS=Homo sapiens OX=9606 GN=RAB11FIP1 PE=1 SV=3"	"0.000"	""	"1"	"2"	"3"	"2"	"1283"	"137.1"	"5.43"	"722.99"	"2.55"	"2"	"1"	"transport;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00168, Pf09457"	"80223"	"ENSG00000156675"	"RAB11FIP1"	"hsa:80223; J3KNP0; Q307T1; Q6AZK4; Q6WKZ2; Q6WKZ4; Q6WKZ6; Q86YV4; Q8TDL1; Q9H642"	""	""	"0"	"0"	"77.2"	"61.7"	"81.7"	"65.7"	"98.8"	"210.3"	"362.4"	"400.0"	"345.0"	"350.5"	"375.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H6D7"	"HAUS augmin-like complex subunit 4 OS=Homo sapiens OX=9606 GN=HAUS4 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"363"	"42.4"	"5.68"	"265.03"	"2.55"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton"	"cytoskeletal activity"	"Pf14735"	"54930"	"ENSG00000092036"	"HAUS4"	"B7WP17; D3DS34; hsa:54930; Q86T15; Q86T16; Q86U43; Q9H6D7; Q9NX59"	""	"Regulation of PLK1 Activity at G2/M Transition; Recruitment of NuMA to mitotic centrosomes; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"7"	"0"	"41.8"	"30.8"	"41.5"	"38.9"	"44.0"	"40.6"	"56.7"	"115.0"	"140.6"	"324.3"	"387.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95235"	"Kinesin-like protein KIF20A OS=Homo sapiens OX=9606 GN=KIF20A PE=1 SV=1"	"0.000"	""	"2"	"2"	"3"	"2"	"890"	"100.2"	"6.92"	"584.54"	"2.54"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"cytoskeleton;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225"	"10112"	"ENSG00000112984"	"KIF20A"	"B4DL79; D3DQB6; hsa:10112; O95235"	""	"COPI-dependent Golgi-to-ER retrograde traffic; MHC class II antigen presentation; Kinesins; Mitotic Telophase/Cytokinesis"	"4"	"0"	"47.4"	"31.2"	"37.8"	"42.5"	"40.9"	"39.3"	"53.2"	"79.7"	"70.0"	"150.7"	"190.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q93050"	"V-type proton ATPase 116 kDa subunit a isoform 1 OS=Homo sapiens OX=9606 GN=ATP6V0A1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"837"	"96.4"	"6.43"	"285.58"	"2.54"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf01496"	"535"	"ENSG00000033627"	"ATP6V0A1"	"B7Z3B7; hsa:535; Q8N5G7; Q93050; Q9NSX0"	""	"Neutrophil degranulation; ROS and RNS production in phagocytes; Insulin receptor recycling; Transferrin endocytosis and recycling; Ion channel transport"	"5"	"0"	"4.0"	"2.1"	"3.3"	"1.8"	"3.0"	"5.3"	"3.4"	"9.9"	"13.3"	"33.4"	"54.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y399"	"28S ribosomal protein S2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS2 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"296"	"33.2"	"9.26"	"282.97"	"2.54"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00318"	"51116"	"ENSG00000122140"	"MRPS2"	"hsa:51116; Q5T899; Q9BSQ4; Q9Y399"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"125.0"	"100.9"	"134.2"	"99.7"	"120.4"	"121.6"	"128.7"	"188.8"	"172.6"	"360.5"	"491.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08243"	"Asparagine synthetase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=ASNS PE=1 SV=4"	"0.000"	""	"3"	"2"	"2"	"2"	"561"	"64.3"	"6.86"	"252.44"	"2.54"	"1"	"1"	"other metabolic processes;stress response;other biological processes"	"cytosol"	"other molecular function"	"Pf00733, Pf13537"	"440"	"ENSG00000070669"	"ASNS"	"A4D1I8; B4DXZ1; B7ZAA9; D6W5R3; E9PCI3; E9PCX6; hsa:440; P08184; P08243; Q15666; Q549T9; Q96HD0"	"Photodynamic therapy-induced unfolded protein response; Amino acid metabolism"	"Aspartate and asparagine metabolism; Response of EIF2AK1 (HRI) to heme deficiency; ATF4 activates genes in response to endoplasmic reticulum  stress; Response of EIF2AK4 (GCN2) to amino acid deficiency"	"6"	"0"	"71.9"	"52.5"	"90.7"	"78.1"	"65.8"	"73.0"	"86.7"	"141.3"	"152.5"	"346.7"	"540.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q02413"	"Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"1049"	"113.7"	"5.03"	""	"2.54"	""	"1"	"cell adhesion;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00028, Pf01049"	"1828"	"ENSG00000134760"	"DSG1"	"B7Z845; hsa:1828; Q02413"	""	"Neutrophil degranulation; Formation of the cornified envelope; RND3 GTPase cycle; Apoptotic cleavage of cell adhesion  proteins; RND2 GTPase cycle"	"6"	"0"	"4.5"	"8.0"	"45.4"	"8.2"	"13.9"	"2.8"	"6.5"	"11.9"	"16.4"	"15.3"	"24.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q68CZ6"	"HAUS augmin-like complex subunit 3 OS=Homo sapiens OX=9606 GN=HAUS3 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"603"	"69.6"	"5.55"	"269.13"	"2.54"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton"	""	"Pf14932"	"79441"	"ENSG00000214367"	"HAUS3"	"B4DF64; hsa:79441; O43606; Q68CZ6; Q8TAZ5; Q9BTJ9"	""	"Regulation of PLK1 Activity at G2/M Transition; Recruitment of NuMA to mitotic centrosomes; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"7"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P56381"	"ATP synthase subunit epsilon, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1E PE=1 SV=2"	"0.000"	""	"14"	"1"	"2"	"1"	"51"	"5.8"	"9.92"	"309.69"	"2.54"	"1"	"1"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf04627"	"514"	"ENSG00000124172"	"ATP5F1E"	"B2RDD0; E1P5H6; hsa:514; P56381; Q53XU6"	"Electron transport chain: OXPHOS system in mitochondria; 7q11.23 copy number variation syndrome; Oxidative phosphorylation"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"5"	"0"	"146.5"	"109.0"	"123.5"	"127.3"	"135.4"	"110.1"	"158.9"	"332.6"	"299.3"	"678.0"	"993.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86XN8"	"RNA-binding protein MEX3D OS=Homo sapiens OX=9606 GN=MEX3D PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"651"	"64.8"	"5.35"	"463.27"	"2.54"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf13920"	"399664"	"ENSG00000181588"	"MEX3D"	"A0PJL8; A1L023; E9PAL6; hsa:399664; Q71M49; Q86XN8"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q15049"	"Membrane protein MLC1 OS=Homo sapiens OX=9606 GN=MLC1 PE=1 SV=5"	""	""	"4"	"1"	"1"	"1"	"377"	"41.1"	"7.49"	""	"2.53"	""	"1"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	""	"23209"	"ENSG00000100427"	"MLC1"	"B3KW61; B7Z659; hsa:23209; Q15049; Q5JZ83; Q8TAG4; Q96RP5; Q9UGY8"	""	""	"0"	"0"	"94.5"	"25.8"	"156.2"	"114.3"	"106.2"	"122.6"	"135.6"	"192.9"	"205.7"	"365.0"	"374.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WWV3"	"Reticulon-4-interacting protein 1, mitochondrial OS=Homo sapiens OX=9606 GN=RTN4IP1 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"396"	"43.6"	"9.11"	"324.12"	"2.53"	"1"	"1"	"developmental processes;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf08240, Pf13602"	"84816"	"ENSG00000130347"	"RTN4IP1"	"hsa:84816; Q8N9B3; Q8WWV3; Q8WZ66; Q9BRA4"	""	""	"0"	"0"	"8.1"	"8.4"	"12.2"	"18.5"	"14.8"	"13.2"	"16.4"	"21.9"	"39.3"	"83.0"	"86.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NZL9"	"Methionine adenosyltransferase 2 subunit beta OS=Homo sapiens OX=9606 GN=MAT2B PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"334"	"37.5"	"7.36"	"385.27"	"2.53"	"1"	"1"	"other metabolic processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf04321"	"27430"	"ENSG00000038274"	"MAT2B"	"B2R5Y6; hsa:27430; Q1WAI7; Q27J92; Q3LIE8; Q567T7; Q6NYC7; Q9BS89; Q9H3E1; Q9NZL9; Q9UJ54"	"Trans-sulfuration pathway; One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways; Methionine de novo and salvage pathway; Methylation pathways"	"Ub-specific processing proteases; Methylation"	"7"	"0"	"39.3"	"33.7"	"44.7"	"35.0"	"32.5"	"27.3"	"48.1"	"97.8"	"92.3"	"202.2"	"348.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NB46"	"Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C OS=Homo sapiens OX=9606 GN=ANKRD52 PE=1 SV=3"	"0.000"	""	"3"	"2"	"3"	"2"	"1076"	"115.0"	"6.48"	"759.17"	"2.53"	"2"	"1"	""	""	""	"Pf00023, Pf12796"	"283373"	"ENSG00000139645"	"ANKRD52"	"A6NE79; B1Q2K2; hsa:283373; Q8NB46"	""	""	"0"	"0"	"17.5"	"12.5"	"15.5"	"12.3"	"12.6"	"18.3"	"22.5"	"40.9"	"42.0"	"92.0"	"113.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6ZWJ1"	"Syntaxin-binding protein 4 OS=Homo sapiens OX=9606 GN=STXBP4 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"553"	"61.6"	"5.20"	"251.98"	"2.53"	"1"	"1"	"stress response;transport;signal transduction;other biological processes"	"other cell component"	"other molecular function"	"Pf00397, Pf00595"	"252983"	"ENSG00000166263"	"STXBP4"	"hsa:252983; Q6ZWJ1; Q8IVZ5"	"Insulin signaling"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P60228"	"Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"445"	"52.2"	"6.04"	""	"2.52"	""	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01399, Pf09440"	"3646"	"ENSG00000104408"	"EIF3E"	"hsa:3646; O43902; P60228; Q64058; Q64059; Q64252; Q6FG33; Q8WVK4"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"8"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8NDI1"	"EH domain-binding protein 1 OS=Homo sapiens OX=9606 GN=EHBP1 PE=1 SV=3"	""	""	"1"	"1"	"1"	"1"	"1231"	"139.9"	"5.35"	""	"2.52"	""	"1"	"transport"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle"	""	"Pf00307, Pf10358, Pf12130"	"23301"	"ENSG00000115504"	"EHBP1"	"hsa:23301; O94977; Q53TG7; Q53TV6; Q580X2; Q6NX72; Q6PIT3; Q6QNV2; Q8NDI1; Q9NWI9"	"Ciliary landscape"	""	"1"	"0"	"8.6"	"6.9"	"10.7"	"11.3"	"13.0"	"13.6"	"10.8"	"24.5"	"17.8"	"41.7"	"45.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61927"	"60S ribosomal protein L37 OS=Homo sapiens OX=9606 GN=RPL37 PE=1 SV=2"	"0.000"	""	"6"	"1"	"2"	"1"	"97"	"11.1"	"11.74"	"251.09"	"2.52"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf01907"	"6167"	"ENSG00000145592"	"RPL37"	"B2R4H2; hsa:6167; P02403; P61927; Q6IBB4; Q99883"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis"	"14"	"0"	"302.0"	"333.8"	"216.1"	"215.6"	"217.6"	"227.2"	"337.5"	"435.0"	"356.6"	"700.9"	"1154.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50552"	"Vasodilator-stimulated phosphoprotein OS=Homo sapiens OX=9606 GN=VASP PE=1 SV=3"	"0.000"	""	"4"	"1"	"2"	"1"	"380"	"39.8"	"8.94"	"343.20"	"2.52"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00568, Pf08776"	"7408"	"ENSG00000125753"	"VASP"	"B2RBT9; hsa:7408; P50552; Q6PIZ1; Q93035"	"Integrin-mediated cell adhesion; Focal adhesion"	"Generation of second messenger molecules; Signaling by ROBO receptors; Cell-extracellular matrix interactions"	"5"	"0"	"13.3"	"11.2"	"15.0"	"12.1"	"14.1"	"14.7"	"21.7"	"28.2"	"31.5"	"62.8"	"85.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q99661"	"Kinesin-like protein KIF2C OS=Homo sapiens OX=9606 GN=KIF2C PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"725"	"81.3"	"7.83"	""	"2.51"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00225"	"11004"	"ENSG00000142945"	"KIF2C"	"B3ITR9; hsa:11004; Q5JR88; Q6ICU1; Q96C18; Q96HB8; Q99661; Q9BWV8"	"Microtubule cytoskeleton regulation"	"Separation of Sister Chromatids; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; COPI-dependent Golgi-to-ER retrograde traffic; Kinesins"	"10"	"0"	"32.7"	"24.1"	"39.7"	"26.4"	"30.4"	"36.5"	"43.9"	"74.8"	"68.7"	"111.2"	"121.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P29144"	"Tripeptidyl-peptidase 2 OS=Homo sapiens OX=9606 GN=TPP2 PE=1 SV=4"	""	""	"1"	"1"	"1"	"1"	"1249"	"138.3"	"6.32"	""	"2.51"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00082, Pf12580"	"7174"	"ENSG00000134900"	"TPP2"	"hsa:7174; P29144; Q5VZU8"	""	"Antigen processing: Ubiquitination & Proteasome degradation"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UN37"	"Vacuolar protein sorting-associated protein 4A OS=Homo sapiens OX=9606 GN=VPS4A PE=1 SV=1"	"0.000"	""	"6"	"2"	"3"	"2"	"437"	"48.9"	"7.80"	"829.70"	"2.51"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00004, Pf04212, Pf09336, Pf17862"	"27183"	"ENSG00000132612"	"VPS4A"	"B2RCB7; hsa:27183; Q8TF07; Q9UI03; Q9UN37; Q9Y582"	"Ebola virus infection in host; Ciliary landscape"	"Budding and maturation of HIV virion; Endosomal Sorting Complex Required For Transport (ESCRT); HCMV Late Events; Sealing of the nuclear envelope (NE) by ESCRT-III"	"6"	"0"	"17.0"	"13.8"	"12.1"	"11.3"	"12.0"	"11.8"	"13.9"	"31.1"	"28.4"	"81.7"	"119.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94804"	"Serine/threonine-protein kinase 10 OS=Homo sapiens OX=9606 GN=STK10 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"968"	"112.1"	"6.95"	"338.57"	"2.51"	"1"	"1"	"cell adhesion;cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf12474"	"6793"	"ENSG00000072786"	"STK10"	"A6ND35; B2R8F5; B3KMY1; hsa:6793; O94804; Q6NSK0; Q9UIW4"	""	"RHOC GTPase cycle; RHOA GTPase cycle; RHOB GTPase cycle; Neutrophil degranulation"	"4"	"0"	"22.8"	"20.8"	"26.7"	"24.1"	"30.9"	"36.9"	"45.9"	"48.2"	"44.8"	"35.7"	"43.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NCD3"	"Holliday junction recognition protein OS=Homo sapiens OX=9606 GN=HJURP PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"748"	"83.5"	"9.31"	"239.64"	"2.51"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf10384, Pf12346, Pf12347"	"55355"	"ENSG00000123485"	"HJURP"	"A8IRH5; B4DWR0; B4DZV4; hsa:55355; Q8NCD3; Q9BUT2; Q9NSL8"	"2q37 copy number variation syndrome"	"Deposition of new CENPA-containing nucleosomes at the centromere"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P48201"	"ATP synthase F(0) complex subunit C3, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5MC3 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"142"	"14.7"	"9.45"	"310.63"	"2.50"	"1"	"1"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00137"	"518"	"ENSG00000154518"	"ATP5MC3"	"B2R4Z0; D3DPF0; hsa:518; P48201; Q4ZFX7"	"Electron transport chain: OXPHOS system in mitochondria; 7q11.23 copy number variation syndrome; Oxidative phosphorylation"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"5"	"0"	"94.1"	"78.9"	"94.1"	"87.8"	"99.4"	"152.0"	"220.4"	"294.6"	"300.7"	"517.4"	"648.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4D1"	"Disheveled-associated activator of morphogenesis 1 OS=Homo sapiens OX=9606 GN=DAAM1 PE=1 SV=2"	"0.001"	""	"1"	"1"	"2"	"1"	"1078"	"123.4"	"7.23"	"235.55"	"2.50"	"1"	"1"	"cell-cell signaling;cell organization and biogenesis;signal transduction"	"plasma membrane;other membranes;cytosol;cytoskeleton"	"cytoskeletal activity;other molecular function"	"Pf02181, Pf06367, Pf06371"	"23002"	"ENSG00000100592"	"DAAM1"	"hsa:23002; Q86U34; Q8N1Z8; Q8TB39; Q9Y4D1"	"Physico-chemical features and toxicity-associated pathways; Wnt signaling"	"RHO GTPases Activate Formins; PCP/CE pathway; RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RHOB GTPase cycle"	"8"	"0"	"70.3"	"50.4"	"66.3"	"57.5"	"57.6"	"63.0"	"75.0"	"131.6"	"142.2"	"299.0"	"387.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q02750"	"Dual specificity mitogen-activated protein kinase kinase 1 OS=Homo sapiens OX=9606 GN=MAP2K1 PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"393"	"43.4"	"6.62"	""	"2.50"	""	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069"	"5604"	"ENSG00000169032"	"MAP2K1"	"hsa:5604; Q02750"	"IL-5 signaling pathway; Osteopontin signaling; MicroRNAs in cardiomyocyte hypertrophy; Integrin-mediated cell adhesion; IL-1 signaling pathway; Thyroxine (thyroid hormone) production; RANKL/RANK signaling pathway; Thyroid stimulating hormone (TSH) signaling pathway; Leptin signaling pathway; Prolactin signaling pathway; IL-7 signaling pathway; Alzheimer's disease and miRNA effects; Endothelin pathways; IL-9 signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; Glioblastoma signaling pathways; Androgen receptor network in prostate cancer; B cell receptor signaling pathway; AGE/RAGE pathway; Interleukin-11 signaling pathway; Corticotropin-releasing hormone signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Aryl hydrocarbon receptor pathway; Common pathways underlying drug addiction; Interleukin-1 (IL-1) structural pathway; Cardiac hypertrophic response; Bladder cancer; IL-3 signaling pathway; Kit receptor signaling pathway; Focal adhesion; Hepatocyte growth factor receptor signaling; IL6 signaling pathway; BDNF-TrkB signaling; Physico-chemical features and toxicity-associated pathways; MAPK signaling pathway; T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection; 4-hydroxytamoxifen, dexamethasone, and retinoic acids regulation of p27 expression; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Chemokine signaling pathway; Embryonic stem cell pluripotency pathways; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Endometrial cancer; PI3K-Akt signaling pathway; Chromosomal and microsatellite instability in colorectal cancer ; MAPK cascade; Ras signaling; Epithelial to mesenchymal transition in colorectal cancer; Non-small cell lung cancer; Breast cancer pathway; Pancreatic adenocarcinoma pathway; Ethanol metabolism production of ROS by CYP2E1; EGF/EGFR signaling pathway; Envelope proteins and their potential roles in EDMD physiopathology; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Gastrin signaling pathway; Hepatitis B infection; Melanoma; Netrin-UNC5B signaling pathway; FGFR3 signaling in chondrocyte proliferation and terminal differentiation; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; Kisspeptin/kisspeptin receptor system in the ovary; Host-pathogen interaction of human coronaviruses - MAPK signaling; IL-2 signaling pathway; MAPK pathway in congenital thyroid cancer; Pleural mesothelioma; Regulation of actin cytoskeleton; Alzheimer's disease; GDNF signaling; A network map of Macrophage-stimulating protein (MSP) signaling; EPO receptor signaling; ErbB signaling pathway; T-cell receptor signaling pathway; Estrogen signaling pathway; Serotonin HTR1 group and FOS pathway; Serotonin receptor 2 and ELK-SRF/GATA4 signaling; Serotonin receptor 4/6/7 and NR3C signaling; Toll-like receptor signaling pathway"	"Signaling by BRAF and RAF1 fusions; Uptake and function of anthrax toxins; Signal transduction by L1; RAF activation; MAP3K8 (TPL2)-dependent MAPK1/3 activation; MAPK3 (ERK1) activation; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; Frs2-mediated activation; Negative feedback regulation of MAPK pathway; Signaling by MAP2K mutants"	"96"	"0"	"3.6"	"2.7"	"6.1"	"6.1"	"3.1"	"3.0"	"5.7"	"13.6"	"12.8"	"81.9"	"210.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UJX3"	"Anaphase-promoting complex subunit 7 OS=Homo sapiens OX=9606 GN=ANAPC7 PE=1 SV=4"	"0.000"	""	"2"	"1"	"2"	"1"	"599"	"66.8"	"5.64"	"357.04"	"2.50"	"1"	"1"	""	""	""	"Pf13432"	"51434"	""	"ANAPC7"	"A0A024RBJ3; hsa:51434"	""	""	"0"	"0"	"29.6"	"25.7"	"24.9"	"20.7"	"21.4"	"23.2"	"32.1"	"43.6"	"55.9"	"138.7"	"201.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16527"	"Cysteine and glycine-rich protein 2 OS=Homo sapiens OX=9606 GN=CSRP2 PE=1 SV=3"	"0.000"	""	"4"	"1"	"2"	"1"	"193"	"20.9"	"8.62"	"259.15"	"2.49"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412"	"1466"	"ENSG00000175183"	"CSRP2"	"hsa:1466; Q16527; Q93030"	"Mesodermal commitment pathway; VEGFA-VEGFR2 signaling; H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity"	""	"3"	"0"	"114.2"	"142.2"	"106.4"	"112.9"	"137.0"	"122.2"	"159.2"	"174.6"	"162.1"	"242.3"	"232.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q71RC2"	"La-related protein 4 OS=Homo sapiens OX=9606 GN=LARP4 PE=1 SV=3"	"0.000"	""	"3"	"2"	"3"	"2"	"724"	"80.5"	"6.61"	"975.32"	"2.49"	"2"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity"	"Pf05383"	"113251"	"ENSG00000161813"	"LARP4"	"A8K6T1; E9PDG5; G3XAA8; G5E976; hsa:113251; Q5CZ97; Q6ZV14; Q71RC2; Q96NF9"	""	""	"0"	"0"	"149.2"	"122.0"	"148.9"	"144.2"	"125.9"	"135.6"	"191.8"	"258.5"	"222.1"	"334.5"	"398.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UPW5"	"Cytosolic carboxypeptidase 1 OS=Homo sapiens OX=9606 GN=AGTPBP1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1226"	"138.4"	"6.15"	"281.13"	"2.49"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00246, Pf18027"	"23287"	"ENSG00000135049"	"AGTPBP1"	"B4DIT6; B4DRZ8; hsa:23287; Q5VV80; Q63HM7; Q658P5; Q6P9D6; Q9H8U6; Q9H9W8; Q9NVK1; Q9UPW5"	""	"Carboxyterminal post-translational modifications of tubulin"	"1"	"0"	"4.6"	"2.6"	"4.8"	"8.4"	"4.4"	"6.1"	"8.0"	"10.9"	"12.7"	"29.8"	"53.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q03701"	"CCAAT/enhancer-binding protein zeta OS=Homo sapiens OX=9606 GN=CEBPZ PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1054"	"120.9"	"5.94"	"289.54"	"2.48"	"1"	"1"	"other biological processes"	"nucleus"	"other molecular function"	"Pf03914"	"10153"	"ENSG00000115816"	"CEBPZ"	"hsa:10153; Q03701; Q8NE75"	"Gastric cancer network 2"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TBF4"	"Zinc finger CCHC-type and RNA-binding motif-containing protein 1 OS=Homo sapiens OX=9606 GN=ZCRB1 PE=1 SV=2"	"0.000"	""	"5"	"1"	"2"	"1"	"217"	"24.6"	"8.53"	"265.30"	"2.48"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf00076, Pf00098"	"85437"	"ENSG00000139168"	"ZCRB1"	"hsa:85437; Q6PJX0; Q8TBF4; Q96TA6"	""	"mRNA Splicing - Minor Pathway; Replication of the SARS-CoV-1 genome; Replication of the SARS-CoV-2 genome"	"3"	"0"	"19.5"	"16.7"	"17.6"	"11.8"	"12.3"	"10.8"	"22.5"	"23.3"	"24.2"	"33.4"	"47.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15347"	"High mobility group protein B3 OS=Homo sapiens OX=9606 GN=HMGB3 PE=1 SV=4"	"0.000"	""	"11"	"2"	"2"	"2"	"200"	"23.0"	"8.37"	"663.32"	"2.48"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00505, Pf09011"	"3149"	"ENSG00000029993"	"HMGB3"	"hsa:3149; O15347; O95556; Q6NS40"	""	""	"0"	"0"	"138.0"	"94.3"	"135.3"	"127.8"	"134.6"	"143.7"	"168.9"	"314.5"	"329.6"	"717.8"	"785.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96DV4"	"39S ribosomal protein L38, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL38 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"380"	"44.6"	"7.53"	"312.43"	"2.48"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	""	"Pf01161"	"64978"	"ENSG00000204316"	"MRPL38"	"B3KN96; hsa:64978; Q96DV4; Q96Q66; Q9P0B9"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"60.1"	"41.5"	"61.1"	"60.6"	"45.6"	"44.5"	"60.8"	"70.4"	"71.6"	"155.0"	"309.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15398"	"Disks large-associated protein 5 OS=Homo sapiens OX=9606 GN=DLGAP5 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"846"	"95.1"	"9.00"	"303.61"	"2.48"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf03359"	"9787"	"ENSG00000126787"	"DLGAP5"	"A8MTM6; B4DRM8; hsa:9787; Q15398; Q86T11; Q8NG58"	"Complement system in neuronal development and plasticity"	"NOTCH3 Intracellular Domain Regulates Transcription"	"2"	"0"	"45.7"	"28.6"	"46.4"	"39.8"	"40.5"	"39.7"	"50.1"	"81.6"	"93.5"	"204.3"	"258.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q69YH5"	"Cell division cycle-associated protein 2 OS=Homo sapiens OX=9606 GN=CDCA2 PE=1 SV=2"	"0.000"	""	"2"	"2"	"3"	"2"	"1023"	"112.6"	"8.40"	"564.68"	"2.48"	"2"	"1"	"cell cycle OR cell proliferation;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf15276"	"157313"	"ENSG00000184661"	"CDCA2"	"hsa:157313; Q3SX74; Q4G0W0; Q5RKN0; Q69YH5; Q69YI4; Q6P464; Q8N7C1"	""	""	"0"	"0"	"31.1"	"28.5"	"20.3"	"20.8"	"17.8"	"18.0"	"35.5"	"43.9"	"37.3"	"49.0"	"58.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96C01"	"Protein FAM136A OS=Homo sapiens OX=9606 GN=FAM136A PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"138"	"15.6"	"7.61"	"308.80"	"2.48"	"1"	"1"	""	"other cell component"	""	"Pf05811"	"84908"	"ENSG00000035141"	"FAM136A"	"hsa:84908; Q96C01; Q96SS3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q6TFL3"	"Coiled-coil domain-containing protein 171 OS=Homo sapiens OX=9606 GN=CCDC171 PE=2 SV=1"	""	""	"1"	"1"	"1"	"1"	"1326"	"152.7"	"6.81"	""	"2.48"	""	"1"	""	""	""	""	"203238"	"ENSG00000164989"	"CCDC171"	"B7ZM22; hsa:203238; Q5SU58; Q6P1W1; Q6TFL3; Q6ZR13; Q8N1Z4; Q8N8L3; Q8TBR2"	""	""	"0"	"0"	"171.7"	"115.9"	"206.5"	"164.2"	"171.6"	"167.0"	"211.6"	"239.1"	"225.1"	"356.0"	"512.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NCM8"	"Cytoplasmic dynein 2 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC2H1 PE=1 SV=4"	"0.000"	""	"0"	"1"	"2"	"1"	"4307"	"492.3"	"6.54"	"243.49"	"2.47"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03028, Pf08385, Pf08393, Pf12774, Pf12775, Pf12777, Pf12780, Pf12781, Pf18198, Pf18199"	"79659"	"ENSG00000187240"	"DYNC2H1"	"hsa:79659; O00432; Q16693; Q3C1U8; Q4AC93; Q6ZMX7; Q6ZUM6; Q7Z363; Q8N977; Q8NCM8; Q92815; Q9HAE4"	"Intraflagellar transport proteins binding to dynein; Genes related to primary cilium development (based on CRISPR); Ciliopathies; 3q29 copy number variation syndrome; Bardet-Biedl syndrome"	"Hedgehog 'off' state; Intraflagellar transport"	"7"	"0"	"6.3"	"3.4"	"9.0"	"6.5"	"9.4"	"6.8"	"8.8"	"30.7"	"32.0"	"72.9"	"96.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BRK5"	"45 kDa calcium-binding protein OS=Homo sapiens OX=9606 GN=SDF4 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"362"	"41.8"	"4.86"	"286.52"	"2.47"	"1"	"1"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf13202, Pf13499"	"51150"	""	"SDF4"	"B1AME5; B1AME6; B2RDF1; B4DSM1; hsa:51150; Q53G52; Q53HQ9; Q8NBQ3; Q96AA1; Q9BRK5; Q9NZP7; Q9UN53"	""	""	"0"	"0"	"176.2"	"145.0"	"201.3"	"151.2"	"137.7"	"149.0"	"189.7"	"412.2"	"376.3"	"715.0"	"812.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43617"	"Trafficking protein particle complex subunit 3 OS=Homo sapiens OX=9606 GN=TRAPPC3 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"180"	"20.3"	"4.96"	"292.05"	"2.47"	"1"	"1"	"cell organization and biogenesis;transport"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf04051"	"27095"	"ENSG00000054116"	"TRAPPC3"	"A6NDN0; B2RDN2; D3DPS2; hsa:27095; O43617"	""	"RAB GEFs exchange GTP for GDP on RABs; COPII-mediated vesicle transport"	"2"	"0"	"50.8"	"35.3"	"50.0"	"42.3"	"37.2"	"39.5"	"70.7"	"171.5"	"181.0"	"558.6"	"855.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51571"	"Translocon-associated protein subunit delta OS=Homo sapiens OX=9606 GN=SSR4 PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"173"	"19.0"	"6.15"	"357.76"	"2.47"	"1"	"1"	""	"other membranes;ER/Golgi;other cell component"	""	"Pf05404"	"6748"	"ENSG00000180879"	"SSR4"	"A8K378; hsa:6748; P51571; Q53XY1"	"VEGFA-VEGFR2 signaling"	"SRP-dependent cotranslational protein targeting to membrane"	"2"	"0"	"43.5"	"30.7"	"51.2"	"39.3"	"48.0"	"51.1"	"47.6"	"104.3"	"86.3"	"184.2"	"273.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P33527"	"Multidrug resistance-associated protein 1 OS=Homo sapiens OX=9606 GN=ABCC1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1531"	"171.5"	"7.11"	"293.42"	"2.46"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes"	"transporter activity;other molecular function"	"Pf00005, Pf00664"	"4363"	"ENSG00000103222; ENSG00000278183"	"ABCC1"	"A3RJX2; C9JPJ4; hsa:4363; O14819; O43333; P33527; P78419; Q59GI9; Q9UQ97; Q9UQ99; Q9UQA0"	"Irinotecan pathway; Leukotriene metabolic pathway; TROP2 regulatory signaling"	"ABC-family proteins mediated transport; Paracetamol ADME; Cytoprotection by HMOX1; Transport of RCbl within the body; Heme degradation; Synthesis of Leukotrienes (LT) and Eoxins (EX)"	"9"	"0"	"2.2"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"2.1"	"9.3"	"16.3"	"66.2"	"101.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q969E8"	"Pre-rRNA-processing protein TSR2 homolog OS=Homo sapiens OX=9606 GN=TSR2 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"191"	"20.9"	"4.39"	"290.31"	"2.46"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf10273"	"90121"	"ENSG00000158526"	"TSR2"	"hsa:90121; Q969E8"	""	""	"0"	"0"	"98.8"	"77.1"	"90.6"	"91.1"	"80.7"	"72.1"	"96.6"	"206.4"	"175.7"	"571.6"	"585.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14191"	"Werner syndrome ATP-dependent helicase OS=Homo sapiens OX=9606 GN=WRN PE=1 SV=2"	"0.000"	""	"2"	"2"	"3"	"2"	"1432"	"162.4"	"6.34"	"530.05"	"2.46"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf00570, Pf01612, Pf09382, Pf14493, Pf16124"	"7486"	"ENSG00000165392"	"WRN"	"A1KYY9; hsa:7486; Q14191"	"Non-homologous end joining; DNA repair pathways, full network; Progeria-associated lipodystrophy; Primary ovarian insufficiency"	"Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; Resolution of D-loop Structures through Holliday Junction Intermediates; Regulation of TP53 Activity through Phosphorylation; Presynaptic phase of homologous DNA pairing and strand exchange; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; SUMOylation of DNA damage response and repair proteins; Removal of the Flap Intermediate from the C-strand"	"21"	"0"	"10.3"	"10.5"	"11.4"	"7.3"	"8.6"	"9.7"	"12.2"	"17.6"	"13.7"	"36.9"	"48.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UNW9"	"RNA-binding protein Nova-2 OS=Homo sapiens OX=9606 GN=NOVA2 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"492"	"49.0"	"8.16"	"247.99"	"2.46"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00013"	"4858"	"ENSG00000104967"	"NOVA2"	"hsa:4858; O43267; Q9UEA1; Q9UNW9"	""	""	"0"	"0"	"95.9"	"72.9"	"86.5"	"86.0"	"98.4"	"95.8"	"106.3"	"137.6"	"120.9"	"215.9"	"330.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UDY2"	"Tight junction protein ZO-2 OS=Homo sapiens OX=9606 GN=TJP2 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1190"	"133.9"	"7.40"	"267.80"	"2.46"	"1"	"1"	"cell adhesion;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00595, Pf00625, Pf07653"	"9414"	"ENSG00000119139"	"TJP2"	"A2A3H9; B7Z2R8; B7Z7T6; F5H301; F5H886; hsa:9414; Q15883; Q5VXL0; Q5VXL1; Q8N756; Q8NI14; Q99839; Q9UDY0; Q9UDY1; Q9UDY2"	"1q21.1 copy number variation syndrome; 15q11q13 copy number variation"	"Signaling by Hippo; RHOC GTPase cycle; RHOA GTPase cycle; RHOB GTPase cycle; Apoptotic cleavage of cell adhesion  proteins"	"7"	"0"	"63.1"	"58.2"	"67.6"	"61.4"	"54.5"	"65.2"	"78.1"	"200.7"	"185.0"	"643.3"	"828.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N567"	"Zinc finger CCHC domain-containing protein 9 OS=Homo sapiens OX=9606 GN=ZCCHC9 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"271"	"30.5"	"9.17"	"237.74"	"2.46"	"1"	"1"	""	"nucleus"	"other molecular function"	"Pf00098"	"84240"	"ENSG00000131732"	"ZCCHC9"	"B2RAE7; hsa:84240; Q8N567; Q9H027"	""	""	"0"	"0"	"101.4"	"95.6"	"77.7"	"103.8"	"87.5"	"91.0"	"120.8"	"165.5"	"152.6"	"243.7"	"309.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99848"	"Probable rRNA-processing protein EBP2 OS=Homo sapiens OX=9606 GN=EBNA1BP2 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"306"	"34.8"	"10.10"	"332.90"	"2.46"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf05890"	"10969"	"ENSG00000117395"	"EBNA1BP2"	"hsa:10969; Q96A66; Q99848"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"80.4"	"56.7"	"81.2"	"60.9"	"72.8"	"67.2"	"79.2"	"147.9"	"125.9"	"314.9"	"418.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NUP7"	"tRNA:m(4)X modification enzyme TRM13 homolog OS=Homo sapiens OX=9606 GN=TRMT13 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"481"	"54.2"	"8.09"	"248.62"	"2.46"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	""	"other molecular function"	"Pf05206, Pf05253, Pf11722"	"54482"	"ENSG00000122435"	"TRMT13"	"hsa:54482; Q5VVL0; Q9NUP7; Q9NW65"	""	"tRNA modification in the nucleus and cytosol"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8WXX5"	"DnaJ homolog subfamily C member 9 OS=Homo sapiens OX=9606 GN=DNAJC9 PE=1 SV=1"	""	""	"9"	"1"	"1"	"1"	"260"	"29.9"	"5.73"	""	"2.46"	""	"1"	"cell organization and biogenesis;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00226"	"23234"	"ENSG00000213551"	"DNAJC9"	"B2RMW6; hsa:23234; Q8WXX5"	""	""	"0"	"0"	"121.4"	"74.0"	"147.4"	"132.3"	"109.6"	"103.5"	"141.3"	"191.9"	"184.3"	"538.5"	"739.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"A3KMH1"	"von Willebrand factor A domain-containing protein 8 OS=Homo sapiens OX=9606 GN=VWA8 PE=1 SV=2"	""	""	"0"	"1"	"1"	"1"	"1905"	"214.7"	"7.40"	""	"2.45"	""	"1"	""	"mitochondrion;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf07728"	"23078"	"ENSG00000102763"	"VWA8"	"A3KMH1; hsa:23078; O60310; Q5JTP6; Q5VW08; Q7Z6I9; Q86YC9; Q8N3E4"	""	""	"0"	"0"	"17.7"	"14.8"	"15.8"	"15.8"	"15.5"	"18.9"	"25.3"	"32.7"	"21.1"	"29.3"	"33.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96DE0"	"U8 snoRNA-decapping enzyme OS=Homo sapiens OX=9606 GN=NUDT16 PE=1 SV=2"	"0.000"	""	"8"	"1"	"2"	"1"	"195"	"21.3"	"6.89"	"319.09"	"2.45"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00293"	"131870"	"ENSG00000198585"	"NUDT16"	"B4E3B4; E9PED4; F5GYJ1; hsa:131870; Q96DE0; Q96N82"	""	"Phosphate bond hydrolysis by NUDT proteins"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NZR1"	"Tropomodulin-2 OS=Homo sapiens OX=9606 GN=TMOD2 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"351"	"39.6"	"5.27"	"289.57"	"2.45"	"1"	"1"	"cell-cell signaling;cell organization and biogenesis;developmental processes;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf03250"	"29767"	"ENSG00000128872"	"TMOD2"	"B4DEW6; hsa:29767; Q9NZR1"	""	"Striated Muscle Contraction"	"1"	"0"	"12.0"	"13.4"	"12.8"	"12.8"	"12.5"	"14.7"	"17.4"	"49.0"	"50.0"	"124.3"	"196.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IWR0"	"Zinc finger CCCH domain-containing protein 7A OS=Homo sapiens OX=9606 GN=ZC3H7A PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"971"	"110.5"	"7.30"	"241.31"	"2.45"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00642"	"29066"	"ENSG00000122299"	"ZC3H7A"	"D3DUG5; hsa:29066; Q8IWR0; Q9NPE9"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q04721"	"Neurogenic locus notch homolog protein 2 OS=Homo sapiens OX=9606 GN=NOTCH2 PE=1 SV=3"	"0.000"	""	"0"	"1"	"2"	"1"	"2471"	"265.2"	"5.14"	"274.50"	"2.45"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00008, Pf00066, Pf06816, Pf07645, Pf07684, Pf12661, Pf12796"	"4853"	"ENSG00000134250"	"NOTCH2"	"hsa:4853; Q04721; Q5T3X7; Q99734; Q9H240"	"Neural crest differentiation; Notch signaling; Canonical and non-canonical Notch signaling; OSX and miRNAs in tooth development; Epithelial to mesenchymal transition in colorectal cancer; Breast cancer pathway; Head and neck squamous cell carcinoma; Osteoblast differentiation and related diseases; Genes controlling nephrogenesis; Primary ovarian insufficiency; Notch signaling pathway"	"NOTCH2 Activation and Transmission of Signal to the Nucleus; Pre-NOTCH Processing in Golgi; Pre-NOTCH Transcription and Translation; Notch-HLH transcription pathway; NOTCH2 intracellular domain regulates transcription; NOTCH4 Intracellular Domain Regulates Transcription; Pre-NOTCH Processing in the Endoplasmic Reticulum; Defective LFNG causes SCDO3"	"19"	"0"	"14.5"	"6.4"	"9.7"	"9.5"	"11.9"	"10.5"	"13.8"	"27.8"	"23.1"	"55.5"	"68.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IYI6"	"Exocyst complex component 8 OS=Homo sapiens OX=9606 GN=EXOC8 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"725"	"81.7"	"5.49"	"311.50"	"2.44"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf08700, Pf16528"	"149371"	"ENSG00000116903"	"EXOC8"	"B3KU33; hsa:149371; Q5TE82; Q8IYI6"	"RalA downstream regulated genes; Ciliary landscape"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8TER0"	"Sushi, nidogen and EGF-like domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNED1 PE=2 SV=2"	""	""	"1"	"1"	"1"	"1"	"1413"	"152.1"	"6.98"	""	"2.44"	""	"1"	"cell adhesion"	"non-structural extracellular;extracellular matrix"	"signal transduction activity or receptor binding;other molecular function"	"Pf00008, Pf00041, Pf06119, Pf12661"	"25992"	"ENSG00000162804"	"SNED1"	"B5MDC3; B7WNK6; B7WPM0; hsa:25992; Q336F4; Q336F5; Q8N369; Q8TEP7; Q8TER0"	"2q37 copy number variation syndrome"	""	"1"	"0"	"104.9"	"66.4"	"92.7"	"88.5"	"84.6"	"80.5"	"126.3"	"123.4"	"103.3"	"177.4"	"316.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13107"	"Ubiquitin carboxyl-terminal hydrolase 4 OS=Homo sapiens OX=9606 GN=USP4 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"963"	"108.5"	"5.71"	"350.43"	"2.44"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00443, Pf06337, Pf14836"	"7375"	"ENSG00000114316"	"USP4"	"A8K6Y0; C9IY91; hsa:7375; O43452; O43453; Q08AK8; Q13107"	""	"Ub-specific processing proteases; Regulation of TNFR1 signaling; TNFR1-induced NF-kappa-B signaling pathway; TNFR1-induced proapoptotic signaling"	"4"	"0"	"31.9"	"20.1"	"28.4"	"21.3"	"24.6"	"21.8"	"25.5"	"33.0"	"27.6"	"37.7"	"54.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15542"	"Transcription initiation factor TFIID subunit 5 OS=Homo sapiens OX=9606 GN=TAF5 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"800"	"86.8"	"5.64"	"282.36"	"2.44"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00400, Pf04494"	"6877"	"ENSG00000148835"	"TAF5"	"A8K5B4; B2RMR0; B7ZKJ6; hsa:6877; Q15542; Q53EM4; Q5SYD5; Q86UZ7; Q9Y4K5"	"Eukaryotic transcription initiation"	"RNA Polymerase II Pre-transcription Events; RNA polymerase II transcribes snRNA genes; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Regulation of TP53 Activity through Phosphorylation"	"11"	"0"	"114.1"	"93.9"	"123.2"	"111.9"	"105.2"	"127.1"	"142.0"	"262.0"	"240.4"	"556.6"	"782.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5JTZ9"	"Alanine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=AARS2 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"985"	"107.3"	"6.27"	"295.61"	"2.44"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf01411, Pf07973"	"57505"	"ENSG00000124608"	"AARS2"	"A2RRN5; hsa:57505; Q5JTZ9; Q8N198; Q96D02; Q9ULF0"	"Primary ovarian insufficiency"	"Mitochondrial tRNA aminoacylation"	"2"	"0"	"34.4"	"27.8"	"36.7"	"30.3"	"25.5"	"25.4"	"34.7"	"93.4"	"77.4"	"501.3"	"713.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UJZ1"	"Stomatin-like protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=STOML2 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"356"	"38.5"	"7.39"	"259.46"	"2.44"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;mitochondrion"	"signal transduction activity or receptor binding;other molecular function"	"Pf01145, Pf16200"	"30968"	"ENSG00000165283"	"STOML2"	"B4E1K7; D3DRN3; hsa:30968; O60376; Q53G29; Q96FY2; Q9P042; Q9UJZ1"	""	"Processing of SMDT1"	"1"	"0"	"35.0"	"29.1"	"36.2"	"28.7"	"32.0"	"32.3"	"34.6"	"55.4"	"45.5"	"82.6"	"85.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N6R0"	"eEF1A lysine and N-terminal methyltransferase OS=Homo sapiens OX=9606 GN=EEF1AKNMT PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"699"	"78.7"	"6.73"	"279.12"	"2.43"	"1"	"1"	"other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01564, Pf08241"	"51603"	"ENSG00000010165"	"METTL13"	"A6NFK0; A8K6S5; hsa:51603; O94940; Q53EZ6; Q5TGP9; Q5TGQ0; Q8N2P8; Q8N6R0; Q96J11; Q96SQ0; Q9Y2Z1; Q9Y3M6"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y266"	"Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"331"	"38.2"	"5.38"	"313.57"	"2.43"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf04969, Pf14050, Pf16273"	"10726"	"ENSG00000090273"	"NUDC"	"hsa:10726; Q5QP31; Q5QP35; Q9H0N2; Q9Y266; Q9Y2B6"	"Ciliary landscape; PAFAH1B1 copy number variation"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; RND2 GTPase cycle"	"9"	"0"	"65.9"	"53.6"	"73.2"	"52.6"	"51.3"	"52.1"	"65.2"	"99.3"	"73.5"	"175.6"	"434.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z4W1"	"L-xylulose reductase OS=Homo sapiens OX=9606 GN=DCXR PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"244"	"25.9"	"8.10"	"257.76"	"2.43"	"1"	"1"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf13561"	"51181"	"ENSG00000169738"	"DCXR"	"hsa:51181; Q7Z4W1; Q9BTZ3; Q9UHY9"	""	"Formation of xylulose-5-phosphate; Essential pentosuria"	"2"	"0"	"144.4"	"117.8"	"145.2"	"136.7"	"125.5"	"140.0"	"182.2"	"378.7"	"422.3"	"912.8"	"1093.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9ULR3"	"Protein phosphatase 1H OS=Homo sapiens OX=9606 GN=PPM1H PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"514"	"56.4"	"6.60"	"316.10"	"2.43"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00481"	"57460"	"ENSG00000111110"	"PPM1H"	"B1Q2A9; B2RXG4; hsa:57460; Q6PI86; Q9ULR3"	""	""	"0"	"0"	"2.9"	"2.6"	"5.1"	"0.0"	"3.6"	"3.8"	"3.4"	"11.6"	"16.3"	"53.1"	"84.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6VY07"	"Phosphofurin acidic cluster sorting protein 1 OS=Homo sapiens OX=9606 GN=PACS1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"963"	"104.8"	"7.74"	"326.54"	"2.43"	"1"	"1"	"other biological processes"	"cytosol;ER/Golgi"	"other molecular function"	"Pf10254"	"55690"	"ENSG00000175115"	"PACS1"	"hsa:55690; Q6PJY6; Q6PKB6; Q6VY07; Q7Z590; Q7Z5W4; Q8N8K6; Q96MW0; Q9NW92; Q9ULP5"	""	"Nef mediated downregulation of MHC class I complex cell surface expression"	"1"	"0"	"28.1"	"20.7"	"23.3"	"25.1"	"18.4"	"23.7"	"22.5"	"45.2"	"57.1"	"112.8"	"127.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16543"	"Hsp90 co-chaperone Cdc37 OS=Homo sapiens OX=9606 GN=CDC37 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"378"	"44.4"	"5.25"	"466.01"	"2.42"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity;other molecular function"	"Pf03234, Pf08564, Pf08565"	"11140"	"ENSG00000105401"	"CDC37"	"hsa:11140; Q16543; Q53YA2"	"TNF-alpha signaling pathway; Aryl hydrocarbon receptor pathway; Aryl hydrocarbon receptor pathway; Nuclear receptors meta-pathway; Interactions between LOXL4 and oxidative stress pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway"	"Regulation of necroptotic cell death; Downregulation of ERBB2 signaling; Signaling by ERBB2 KD Mutants; Signaling by ERBB2 TMD/JMD mutants; RHOBTB2 GTPase cycle; Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; Constitutive Signaling by EGFRvIII; Signaling by ERBB2 ECD mutants; Constitutive Signaling by Overexpressed ERBB2; Drug-mediated inhibition of ERBB2 signaling; Resistance of ERBB2 KD mutants to trastuzumab; Resistance of ERBB2 KD mutants to sapitinib; Resistance of ERBB2 KD mutants to tesevatinib; Resistance of ERBB2 KD mutants to neratinib; Resistance of ERBB2 KD mutants to osimertinib; Resistance of ERBB2 KD mutants to afatinib; Resistance of ERBB2 KD mutants to AEE788; Resistance of ERBB2 KD mutants to lapatinib; Drug resistance in ERBB2 TMD/JMD mutants"	"27"	"0"	"62.8"	"34.0"	"68.4"	"76.5"	"65.5"	"53.3"	"74.8"	"106.6"	"93.4"	"168.0"	"238.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P087"	"Mitochondrial mRNA pseudouridine synthase RPUSD3 OS=Homo sapiens OX=9606 GN=RPUSD3 PE=1 SV=3"	"0.000"	""	"3"	"1"	"3"	"1"	"351"	"38.4"	"10.32"	"591.16"	"2.42"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf00849"	"285367"	"ENSG00000156990"	"RPUSD3"	"B4DS39; hsa:285367; Q6P087; Q6P6A9; Q8N1B2; Q8NAV3"	""	""	"0"	"0"	"11.3"	"3.8"	"11.0"	"15.0"	"4.2"	"7.8"	"9.8"	"22.1"	"23.8"	"54.1"	"61.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y376"	"Calcium-binding protein 39 OS=Homo sapiens OX=9606 GN=CAB39 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"341"	"39.8"	"6.89"	"316.01"	"2.42"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"non-structural extracellular;other membranes;cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;other molecular function"	"Pf08569"	"51719"	"ENSG00000135932"	"CAB39"	"A8K8L7; hsa:51719; Q9Y376"	"AMP-activated protein kinase signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Endochondral ossification; Endochondral ossification with skeletal dysplasias"	"Neutrophil degranulation; Energy dependent regulation of mTOR by LKB1-AMPK"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WVD3"	"E3 ubiquitin-protein ligase RNF138 OS=Homo sapiens OX=9606 GN=RNF138 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"245"	"28.2"	"6.93"	"278.68"	"2.42"	"1"	"1"	"cell-cell signaling;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05605, Pf13923, Pf18574"	"51444"	"ENSG00000134758"	"RNF138"	"B2RE17; hsa:51444; Q8WVD3; Q9H8K2; Q9UF87; Q9UKI6"	""	"Antigen processing: Ubiquitination & Proteasome degradation"	"1"	"0"	"103.7"	"96.1"	"98.3"	"93.7"	"104.0"	"97.9"	"129.0"	"327.5"	"288.5"	"381.0"	"381.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P17706"	"Tyrosine-protein phosphatase non-receptor type 2 OS=Homo sapiens OX=9606 GN=PTPN2 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"415"	"48.4"	"8.29"	"252.36"	"2.42"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00102"	"5771"	"ENSG00000175354"	"PTPN2"	"A8K955; A8MXU3; hsa:5771; K7ENG3; P17706; Q96AU5; Q96HR2"	"Immune response to tuberculosis; 5q35 copy number variation"	"Negative regulation of MET activity; Interleukin-37 signaling"	"4"	"0"	"0.0"	"0.0"	"2.5"	"0.0"	"2.3"	"3.3"	"2.0"	"13.2"	"16.7"	"42.2"	"64.4"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05549"	"Transcription factor AP-2-alpha OS=Homo sapiens OX=9606 GN=TFAP2A PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"437"	"48.0"	"8.02"	"267.16"	"2.42"	"1"	"1"	"developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03299"	"7020"	"ENSG00000137203"	"TFAP2A"	"hsa:7020; P05549; Q13777; Q5TAV5; Q8N1C6"	"Neural crest differentiation; Corticotropin-releasing hormone signaling pathway; Ectoderm differentiation; Hypothetical craniofacial development pathway; Ebola virus infection in host; lncRNA in canonical Wnt signaling and colorectal cancer; Ciliary landscape; Galanin receptor pathway; SARS-CoV-2 innate immunity evasion and cell-specific immune response; CCL18 signaling pathway"	"Activation of the TFAP2 (AP-2) family of transcription factors; TFAP2 (AP-2) family regulates transcription of growth factors and their receptors; TFAP2 (AP-2) family regulates transcription of cell cycle factors; Negative regulation of activity of TFAP2 (AP-2) family transcription factors; TFAP2 (AP-2) family regulates transcription of other transcription factors; TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"	"17"	"0"	"13.9"	"13.8"	"19.2"	"10.9"	"15.4"	"16.7"	"26.0"	"29.8"	"30.5"	"51.8"	"62.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9GZS1"	"DNA-directed RNA polymerase I subunit RPA49 OS=Homo sapiens OX=9606 GN=POLR1E PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"419"	"47.2"	"8.94"	"304.00"	"2.41"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf06870"	"64425"	"ENSG00000137054"	"POLR1E"	"hsa:64425; Q5VZT3; Q8NBA9; Q96L20; Q9GZS1"	"Pyrimidine metabolism; Eukaryotic transcription initiation; 2q13 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Initiation; RNA Polymerase I Transcription Termination"	"8"	"0"	"17.8"	"10.8"	"13.2"	"12.5"	"14.1"	"9.3"	"20.5"	"39.3"	"34.8"	"86.5"	"104.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NSE4"	"Isoleucine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=IARS2 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1012"	"113.7"	"7.20"	"254.28"	"2.41"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00133, Pf06827, Pf08264"	"55699"	"ENSG00000067704"	"IARS2"	"B2RPG8; hsa:55699; Q1M2P9; Q6PI85; Q7L439; Q86WU9; Q96D91; Q9H9Q8; Q9NSE4; Q9NW42"	""	"Mitochondrial tRNA aminoacylation"	"1"	"0"	"10.2"	"5.6"	"10.0"	"8.5"	"8.6"	"5.0"	"8.8"	"18.9"	"21.7"	"45.7"	"99.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BPZ3"	"Polyadenylate-binding protein-interacting protein 2 OS=Homo sapiens OX=9606 GN=PAIP2 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"127"	"15.0"	"4.12"	"251.87"	"2.41"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other cell component"	"nucleic acid binding activity;other molecular function"	"Pf07145"	"51247"	"ENSG00000120727"	"PAIP2"	"B2RBI1; D3DQC6; hsa:51247; Q49A06; Q9BPZ3; Q9H0Y5; Q9P0Q8"	""	""	"0"	"0"	"229.8"	"191.4"	"195.2"	"194.9"	"181.6"	"195.8"	"234.7"	"273.0"	"245.1"	"451.2"	"692.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O14639"	"Actin-binding LIM protein 1 OS=Homo sapiens OX=9606 GN=ABLIM1 PE=1 SV=3"	""	""	"1"	"1"	"1"	"1"	"778"	"87.6"	"8.59"	""	"2.41"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412, Pf02209, Pf16182"	"3983"	"ENSG00000099204"	"ABLIM1"	"A6NI16; A6NJ06; A8MXA9; B3KVH2; hsa:3983; O14639; Q15039; Q5JVV1; Q5JVV2; Q5T6N2; Q5T6N3; Q5T6N5; Q68CQ9; Q9BUP1"	"Male infertility"	"DCC mediated attractive signaling"	"2"	"0"	"10.2"	"7.0"	"12.2"	"8.0"	"11.0"	"7.9"	"11.9"	"25.3"	"23.6"	"41.2"	"50.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O96008"	"Mitochondrial import receptor subunit TOM40 homolog OS=Homo sapiens OX=9606 GN=TOMM40 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"361"	"37.9"	"7.25"	"255.22"	"2.41"	"1"	"1"	"cell organization and biogenesis;transport"	"other membranes;cytosol;mitochondrion;other cell component"	"transporter activity"	"Pf01459"	"10452"	"ENSG00000130204"	"TOMM40"	"A0A024R0P9; hsa:10452; O96008; Q86VW4; Q8WY09; Q8WY10; Q8WY11; Q9BR95"	"IL-18 signaling pathway"	"Mitochondrial protein import; PINK1-PRKN Mediated Mitophagy"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P1N0"	"Coiled-coil and C2 domain-containing protein 1A OS=Homo sapiens OX=9606 GN=CC2D1A PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"951"	"104.0"	"8.09"	"332.57"	"2.40"	"1"	"1"	"other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00168"	"54862"	"ENSG00000132024; ENSG00000288293"	"CC2D1A"	"hsa:54862; Q6P1N0; Q7Z435; Q86XV0; Q8NF89; Q9H603; Q9NXI1"	"Sudden infant death syndrome (SIDS) susceptibility pathways"	""	"1"	"0"	"46.5"	"31.4"	"50.8"	"52.7"	"48.3"	"43.2"	"54.8"	"84.0"	"95.5"	"190.6"	"277.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N4C8"	"Misshapen-like kinase 1 OS=Homo sapiens OX=9606 GN=MINK1 PE=1 SV=2"	"0.000"	""	"2"	"2"	"3"	"1"	"1332"	"149.7"	"7.85"	"630.08"	"2.40"	"2"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;ER/Golgi;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00780"	"50488"	"ENSG00000141503"	"MINK1"	"D3DTK3; D3DTK4; hsa:50488; Q5U8Z0; Q8N4C8; Q9P1X1; Q9P2R8"	"Angiopoietin-like protein 8 regulatory pathway; Hippo-YAP signaling; Insulin signaling; Pleural mesothelioma"	"Oxidative Stress Induced Senescence"	"5"	"0"	"6.2"	"6.4"	"5.6"	"7.7"	"7.3"	"5.0"	"11.2"	"20.7"	"19.4"	"12.3"	"13.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8IXQ5"	"Kelch-like protein 7 OS=Homo sapiens OX=9606 GN=KLHL7 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"586"	"65.9"	"6.48"	""	"2.40"	""	"1"	"protein metabolism;other metabolic processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00651, Pf01344, Pf07707"	"55975"	"ENSG00000122550"	"KLHL7"	"A4D144; B7Z5I9; G5E9G3; hsa:55975; Q7Z765; Q8IXQ5; Q96MV2; Q9BQF8; Q9UDQ9"	""	""	"0"	"0"	"45.4"	"36.0"	"44.6"	"40.7"	"41.9"	"39.6"	"52.2"	"216.4"	"230.4"	"910.7"	"1198.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N5L8"	"Ribonuclease P protein subunit p25-like protein OS=Homo sapiens OX=9606 GN=RPP25L PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"163"	"17.6"	"10.30"	"295.34"	"2.39"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf01918"	"138716"	"ENSG00000164967"	"RPP25L"	"D3DRM5; hsa:138716; Q8N5L8"	""	""	"0"	"0"	"67.6"	"38.5"	"76.8"	"75.4"	"75.5"	"67.8"	"97.4"	"111.7"	"95.5"	"164.5"	"197.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9P2R7"	"Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLA2 PE=1 SV=3"	""	""	"2"	"1"	"1"	"1"	"463"	"50.3"	"7.42"	""	"2.39"	""	"1"	"other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf00549, Pf08442"	"8803"	"ENSG00000136143"	"SUCLA2"	"B2RDE7; hsa:8803; O95194; Q5T9Q4; Q5T9Q6; Q9NV21; Q9NVP7; Q9P2R7"	""	"Citric acid cycle (TCA cycle)"	"1"	"0"	"32.3"	"19.9"	"42.6"	"52.0"	"53.1"	"32.7"	"50.0"	"77.6"	"83.6"	"196.5"	"324.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3D9"	"28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2"	"0.000"	""	"5"	"1"	"2"	"1"	"190"	"21.8"	"8.90"	"378.13"	"2.39"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf10484"	"51649"	"ENSG00000181610"	"MRPS23"	"B2R6V3; hsa:51649; Q96Q24; Q9BWH8; Q9P053; Q9Y3D9"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"41.2"	"35.4"	"59.2"	"43.7"	"42.9"	"39.2"	"60.4"	"94.8"	"88.1"	"185.5"	"286.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBB5"	"Methyl-CpG-binding domain protein 2 OS=Homo sapiens OX=9606 GN=MBD2 PE=1 SV=1"	"0.000"	""	"5"	"2"	"3"	"1"	"411"	"43.2"	"10.04"	"775.03"	"2.39"	"2"	"1"	"cell-cell signaling;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01429, Pf14048, Pf16564"	"8932"	"ENSG00000134046"	"MBD2"	"hsa:8932; O95242; Q9UBB5; Q9UIS8"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"NoRC negatively regulates rRNA expression; RNA Polymerase I Promoter Opening"	"3"	"0"	"8.3"	"7.4"	"4.6"	"5.8"	"8.3"	"5.2"	"13.8"	"13.9"	"16.6"	"33.9"	"53.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P16885"	"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 OS=Homo sapiens OX=9606 GN=PLCG2 PE=1 SV=4"	"0.000"	""	"1"	"1"	"3"	"1"	"1265"	"147.8"	"6.64"	"514.31"	"2.38"	"1"	"1"	"cell-cell signaling;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00017, Pf00018, Pf00168, Pf00387, Pf00388"	"5336"	"ENSG00000197943"	"PLCG2"	"D3DUL3; hsa:5336; P16885; Q3ZTS2; Q59H45; Q969T5"	"Leptin signaling pathway; Glioblastoma signaling pathways; B cell receptor signaling pathway; Corticotropin-releasing hormone signaling pathway; Myometrial relaxation and contraction pathways; Microglia pathogen phagocytosis pathway; GPR40 pathway; Ras signaling; Non-small cell lung cancer; Non-genomic actions of 1,25 dihydroxyvitamin D3; Resistin as a regulator of inflammation; EGFR tyrosine kinase inhibitor resistance; GDNF signaling; 2q13 copy number variation syndrome; ErbB signaling pathway"	"Generation of second messenger molecules; Role of phospholipids in phagocytosis; FCERI mediated MAPK activation; FCERI mediated Ca+2 mobilization; FCGR3A-mediated IL10 synthesis; Potential therapeutics for SARS; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; CLEC7A (Dectin-1) signaling; Toll Like Receptor 4 (TLR4) Cascade; GPVI-mediated activation cascade; DAP12 signaling; Synthesis of IP3 and IP4 in the cytosol; Signaling by CSF1 (M-CSF) in myeloid cells; Erythropoietin activates Phospholipase C gamma (PLCG); Dectin-2 family"	"30"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96FF9"	"Sororin OS=Homo sapiens OX=9606 GN=CDCA5 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"252"	"27.6"	"9.61"	"285.94"	"2.38"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf09666"	"113130"	"ENSG00000146670"	"CDCA5"	"A8K625; hsa:113130; Q96FF9"	""	"Resolution of Sister Chromatid Cohesion; Separation of Sister Chromatids; Establishment of Sister Chromatid Cohesion"	"3"	"0"	"430.0"	"374.4"	"402.3"	"390.6"	"369.6"	"369.0"	"475.3"	"446.8"	"416.1"	"476.4"	"538.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P49639"	"Homeobox protein Hox-A1 OS=Homo sapiens OX=9606 GN=HOXA1 PE=1 SV=2"	""	""	"4"	"1"	"1"	"1"	"335"	"36.6"	"8.05"	""	"2.38"	""	"1"	"developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00046"	"3198"	""	"HOXA1"	"A4D184; B2R8U7; hsa:3198; O43363; P49639"	""	"Activation of anterior HOX genes in hindbrain development during early embryogenesis"	"1"	"0"	"111.6"	"40.0"	"170.6"	"128.1"	"127.4"	"145.0"	"172.2"	"214.1"	"275.6"	"388.1"	"361.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5T440"	"Putative transferase CAF17, mitochondrial OS=Homo sapiens OX=9606 GN=IBA57 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"356"	"38.1"	"9.83"	"251.35"	"2.37"	"1"	"1"	"cell organization and biogenesis;other metabolic processes"	"mitochondrion"	"other molecular function"	""	"200205"	"ENSG00000181873"	"IBA57"	"hsa:200205; Q5T440"	""	""	"0"	"0"	"56.7"	"29.8"	"62.4"	"46.6"	"48.9"	"51.0"	"58.3"	"134.8"	"130.0"	"249.0"	"296.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08240"	"Signal recognition particle receptor subunit alpha OS=Homo sapiens OX=9606 GN=SRPRA PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"638"	"69.8"	"8.95"	"320.15"	"2.37"	"1"	"1"	"cell organization and biogenesis;transport"	"other membranes;ER/Golgi"	"other molecular function"	"Pf00448, Pf02881, Pf04086"	"6734"	"ENSG00000182934"	"SRPRA"	"A6NIB3; B2R5Z8; B4E0H3; E9PJS4; hsa:6734; P08240; Q9BVJ4"	""	"XBP1(S) activates chaperone genes; SRP-dependent cotranslational protein targeting to membrane"	"2"	"0"	"4.0"	"4.8"	"6.8"	"4.4"	"6.9"	"7.2"	"7.9"	"23.9"	"21.1"	"45.5"	"44.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O95759"	"TBC1 domain family member 8 OS=Homo sapiens OX=9606 GN=TBC1D8 PE=1 SV=3"	""	""	"1"	"1"	"1"	"1"	"1140"	"130.8"	"5.52"	""	"2.37"	""	"1"	"other biological processes"	"other membranes"	"enzyme regulator activity"	"Pf00566, Pf02893"	"11138"	"ENSG00000204634"	"TBC1D8"	"A6NDL4; A8K9W1; B9A6K4; hsa:11138; O95759; Q53SQ4; Q9UQ32"	""	""	"0"	"0"	"51.5"	"40.6"	"56.9"	"56.0"	"61.9"	"93.8"	"163.3"	"339.4"	"300.9"	"334.8"	"351.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N9B5"	"Junction-mediating and -regulatory protein OS=Homo sapiens OX=9606 GN=JMY PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"988"	"111.4"	"6.18"	"321.90"	"2.37"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"other membranes;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf15871, Pf15920"	"133746"	"ENSG00000152409"	"JMY"	"A1L4P5; B5MDS2; B5MDT0; hsa:133746; Q8N9B5"	""	"Regulation of TP53 Activity through Methylation"	"1"	"0"	"2.7"	"2.8"	"9.7"	"5.3"	"5.5"	"4.7"	"5.6"	"26.2"	"27.1"	"96.6"	"99.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95433"	"Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"338"	"38.3"	"5.53"	"268.43"	"2.36"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi"	"other molecular function"	"Pf08327, Pf09229"	"10598"	"ENSG00000100591"	"AHSA1"	"B2R9L2; B4DUR9; hsa:10598; O95433; Q96IL6; Q9P060"	"T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection"	""	"1"	"0"	"2.0"	"0.0"	"4.3"	"0.0"	"2.4"	"2.9"	"4.4"	"8.6"	"8.3"	"22.5"	"65.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P56556"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 OS=Homo sapiens OX=9606 GN=NDUFA6 PE=1 SV=4"	"0.000"	""	"6"	"1"	"2"	"1"	"128"	"15.1"	"9.98"	"317.83"	"2.36"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;stress response;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf05347"	"4700"	"ENSG00000184983; ENSG00000272765; ENSG00000273397; ENSG00000277365; ENSG00000281013"	"NDUFA6"	"B2RE54; hsa:4700; O43675; P56556; Q6FGW0; Q6IBT8; Q6IC39"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"79.6"	"62.7"	"85.9"	"89.2"	"70.0"	"71.9"	"102.8"	"223.4"	"235.0"	"730.3"	"999.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IXI1"	"Mitochondrial Rho GTPase 2 OS=Homo sapiens OX=9606 GN=RHOT2 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"618"	"68.1"	"5.86"	"277.95"	"2.36"	"1"	"1"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf00071, Pf08355, Pf08356"	"89941"	"ENSG00000140983"	"RHOT2"	"A2IDC2; hsa:89941; Q8IXI1; Q8NF53; Q96C13; Q96S17; Q9BT60; Q9H7M8"	""	"RHOT2 GTPase cycle"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NRY4"	"Rho GTPase-activating protein 35 OS=Homo sapiens OX=9606 GN=ARHGAP35 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1499"	"170.4"	"6.64"	"252.74"	"2.36"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00071, Pf00620, Pf01846, Pf16512, Pf19518"	"2909"	"ENSG00000160007"	"ARHGAP35"	"A7E2A4; hsa:2909; Q14452; Q9C0E1; Q9NRY4"	"Focal adhesion; Regulation of actin cytoskeleton"	"RHOA GTPase cycle; RHOC GTPase cycle; RND2 GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOB GTPase cycle; RHOD GTPase cycle; RHOJ GTPase cycle; RND3 GTPase cycle; RND1 GTPase cycle; Sema4D mediated inhibition of cell attachment and migration; PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"	"18"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12792"	"Twinfilin-1 OS=Homo sapiens OX=9606 GN=TWF1 PE=1 SV=3"	"0.001"	""	"6"	"2"	"2"	"1"	"350"	"40.3"	"6.96"	"231.51"	"2.36"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00241"	"5756"	"ENSG00000151239"	"TWF1"	"A8K5A8; B3KXS6; B4DLX9; hsa:5756; Q12792; Q59G07; Q5U0B1; Q6FHJ1; Q6FHL6; Q6NUK9; Q86XL6; Q8TCD3"	""	"Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; RHOBTB2 GTPase cycle"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q02241"	"Kinesin-like protein KIF23 OS=Homo sapiens OX=9606 GN=KIF23 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"960"	"110.0"	"8.51"	"284.17"	"2.36"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225, Pf16540"	"9493"	"ENSG00000137807"	"KIF23"	"B4E1K0; hsa:9493; Q02241; Q8WVP0"	"Pleural mesothelioma"	"MHC class II antigen presentation; COPI-dependent Golgi-to-ER retrograde traffic; Kinesins; Mitotic Telophase/Cytokinesis"	"5"	"0"	"88.0"	"57.1"	"82.9"	"81.2"	"75.2"	"82.4"	"98.7"	"144.3"	"149.4"	"299.3"	"375.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96BH1"	"E3 ubiquitin-protein ligase RNF25 OS=Homo sapiens OX=9606 GN=RNF25 PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"459"	"51.2"	"6.54"	""	"2.36"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus"	"other molecular function"	"Pf05773"	"64320"	"ENSG00000163481"	"RNF25"	"A8K0D6; hsa:64320; Q53HQ5; Q96BH1; Q9H874"	""	"Antigen processing: Ubiquitination & Proteasome degradation"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46087"	"Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NOP2 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"812"	"89.2"	"9.23"	"274.12"	"2.36"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf01189, Pf08062, Pf17125"	"4839"	"ENSG00000111641"	"NOP2"	"A1A4Z3; B3KPD6; hsa:4839; P46087; Q05BA7; Q0P5S5; Q3KQS4; Q58F30"	"Imatinib and chronic myeloid leukemia"	"rRNA modification in the nucleus and cytosol; TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"	"3"	"0"	"18.9"	"15.5"	"17.1"	"19.3"	"17.0"	"16.8"	"24.6"	"33.6"	"34.7"	"69.7"	"95.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14617"	"AP-3 complex subunit delta-1 OS=Homo sapiens OX=9606 GN=AP3D1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1153"	"130.1"	"8.48"	"251.66"	"2.35"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf01602, Pf06375"	"8943"	"ENSG00000065000"	"AP3D1"	"hsa:8943; O00202; O14617; O75262; Q59HF5; Q96G11; Q9H3C6"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H0U3"	"Magnesium transporter protein 1 OS=Homo sapiens OX=9606 GN=MAGT1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"335"	"38.0"	"9.63"	"357.98"	"2.35"	"1"	"1"	"protein metabolism;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle"	"transporter activity"	"Pf04756"	"84061"	"ENSG00000102158"	"MAGT1"	"B2RAR4; D3DTE3; hsa:84061; Q53G00; Q6P577; Q8NBN6; Q9H0U3"	""	"Neutrophil degranulation; Miscellaneous transport and binding events; Asparagine N-linked glycosylation; Maturation of spike protein"	"4"	"0"	"28.5"	"33.7"	"36.2"	"32.7"	"23.2"	"24.6"	"38.1"	"49.8"	"50.6"	"85.7"	"123.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15345"	"Leucine-rich repeat-containing protein 41 OS=Homo sapiens OX=9606 GN=LRRC41 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"812"	"88.6"	"8.38"	"327.09"	"2.35"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	""	"10489"	"ENSG00000132128"	"LRRC41"	"A8K5G8; hsa:10489; Q15345; Q3MJ96; Q5TDF5; Q71RA8; Q9BSM0"	""	"Antigen processing: Ubiquitination & Proteasome degradation; Neddylation; RHOBTB3 ATPase cycle"	"3"	"0"	"48.5"	"20.9"	"51.7"	"49.6"	"52.8"	"35.3"	"53.0"	"72.8"	"57.5"	"86.5"	"79.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VUA4"	"Zinc finger protein 318 OS=Homo sapiens OX=9606 GN=ZNF318 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"2279"	"251.0"	"7.20"	"281.18"	"2.35"	"1"	"1"	"cell cycle OR cell proliferation;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	""	"24149"	"ENSG00000171467"	"ZNF318"	"hsa:24149; O94796; Q4G0E4; Q5VUA4; Q8NEM6; Q9UNU8; Q9Y2W9"	"Androgen receptor signaling pathway"	""	"1"	"0"	"17.5"	"19.2"	"9.2"	"12.9"	"10.3"	"11.6"	"12.0"	"24.2"	"22.1"	"44.1"	"67.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19622"	"Homeobox protein engrailed-2 OS=Homo sapiens OX=9606 GN=EN2 PE=2 SV=3"	"0.000"	""	"5"	"1"	"2"	"1"	"333"	"34.2"	"9.44"	"327.96"	"2.35"	"1"	"1"	"developmental processes;other biological processes"	"other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00046, Pf10525"	"2020"	"ENSG00000164778"	"EN2"	"A4D252; hsa:2020; P19622; Q549U3; Q9UD58"	"Dopaminergic neurogenesis"	""	"1"	"0"	"23.8"	"20.1"	"36.6"	"27.6"	"33.7"	"33.8"	"44.7"	"79.6"	"66.2"	"142.9"	"152.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NQT4"	"Exosome complex component RRP46 OS=Homo sapiens OX=9606 GN=EXOSC5 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"235"	"25.2"	"7.59"	"385.18"	"2.35"	"1"	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01138, Pf03725"	"56915"	"ENSG00000077348"	"EXOSC5"	"hsa:56915; Q32Q81; Q8NG16; Q96I89; Q9NQT4"	""	"ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Major pathway of rRNA processing in the nucleolus and cytosol; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	"6"	"0"	"38.0"	"34.0"	"36.5"	"34.2"	"36.5"	"41.3"	"51.7"	"93.7"	"100.6"	"347.4"	"539.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8NG48"	"Protein Lines homolog 1 OS=Homo sapiens OX=9606 GN=LINS1 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"757"	"85.8"	"6.52"	""	"2.34"	""	"1"	"other biological processes"	""	""	"Pf14694, Pf14695"	"55180"	"ENSG00000140471"	"LINS1"	"hsa:55180; Q8NG48; Q96FW2; Q9NVQ3"	""	""	"0"	"0"	"155.8"	"134.4"	"146.9"	"142.7"	"131.7"	"145.8"	"175.5"	"196.0"	"207.2"	"424.9"	"592.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N4C6"	"Ninein OS=Homo sapiens OX=9606 GN=NIN PE=1 SV=4"	"0.000"	""	"0"	"1"	"2"	"1"	"2090"	"243.1"	"5.03"	"285.23"	"2.33"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	""	"51199"	"ENSG00000100503"	"NIN"	"A6NDB8; B7WPA3; C9JSB6; C9JSG2; C9JXL2; hsa:51199; Q5BKU3; Q6P0P6; Q8N4C6; Q9BWU6; Q9C012; Q9C013; Q9C014; Q9H5I6; Q9HAT7; Q9HBY5; Q9HCK7; Q9UH61"	""	""	"0"	"0"	"5.8"	"2.2"	"3.9"	"6.9"	"4.0"	"5.6"	"5.4"	"14.0"	"11.2"	"24.9"	"39.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O60704"	"Protein-tyrosine sulfotransferase 2 OS=Homo sapiens OX=9606 GN=TPST2 PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"377"	"41.9"	"9.09"	""	"2.33"	""	"1"	"protein metabolism;other metabolic processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf13469"	"8459"	"ENSG00000128294"	"TPST2"	"B3KQA7; hsa:8459; O60704; Q6FI98; Q9H0V4"	""	"Cytosolic sulfonation of small molecules; Gamma carboxylation, hypusine formation and arylsulfatase activation; Defective F8 sulfation at Y1699"	"3"	"0"	"71.6"	"25.7"	"107.9"	"73.2"	"81.6"	"105.3"	"159.6"	"306.7"	"321.5"	"655.6"	"747.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A6H8Y1"	"Transcription factor TFIIIB component B'' homolog OS=Homo sapiens OX=9606 GN=BDP1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"2624"	"293.7"	"5.11"	"299.01"	"2.33"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf15963"	"55814"	"ENSG00000145734; ENSG00000273873"	"BDP1"	"A6H8Y1; hsa:55814; Q68DS6; Q68DY5; Q6MZL9; Q6PIM7; Q86W98; Q96LR8; Q9C0H4; Q9H197; Q9H1A1; Q9HAW1; Q9HAW2; Q9HCY0; Q9ULH9"	""	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96B01"	"RAD51-associated protein 1 OS=Homo sapiens OX=9606 GN=RAD51AP1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"352"	"38.4"	"9.11"	"309.13"	"2.32"	"1"	"1"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf15696"	"10635"	"ENSG00000111247"	"RAD51AP1"	"A8K7D3; hsa:10635; O43403; Q7Z779; Q96B01"	""	"Resolution of D-loop Structures through Holliday Junction Intermediates; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Homologous DNA Pairing and Strand Exchange; Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2"	"8"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q969Z0"	"FAST kinase domain-containing protein 4 OS=Homo sapiens OX=9606 GN=TBRG4 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"631"	"70.7"	"7.42"	"315.34"	"2.32"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"mitochondrion;other cell component"	""	"Pf06743, Pf08368, Pf08373"	"9238"	"ENSG00000136270"	"TBRG4"	"A4D2L2; A4D2L3; D3DVL5; D3DVL6; hsa:9238; O14710; Q53GI8; Q8NDM4; Q969Z0; Q9BUC6; Q9Y2F6"	""	""	"0"	"0"	"108.0"	"89.0"	"108.4"	"105.6"	"106.8"	"109.6"	"152.6"	"410.4"	"403.9"	"903.4"	"1115.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13325"	"Interferon-induced protein with tetratricopeptide repeats 5 OS=Homo sapiens OX=9606 GN=IFIT5 PE=1 SV=1"	"0.000"	""	"4"	"2"	"2"	"1"	"482"	"55.8"	"7.40"	"254.11"	"2.32"	"1"	"1"	"stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"nucleic acid binding activity"	"Pf13181, Pf13374, Pf13424"	"24138"	"ENSG00000152778"	"IFIT5"	"B2R5X9; B4DDV1; hsa:24138; Q13325; Q5T7I9; Q6IAX3"	""	"Interferon alpha/beta signaling"	"1"	"0"	"4.1"	"2.1"	"3.4"	"3.8"	"3.0"	"4.0"	"3.8"	"10.8"	"8.8"	"28.4"	"42.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35270"	"Sepiapterin reductase OS=Homo sapiens OX=9606 GN=SPR PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"261"	"28.0"	"8.05"	"323.50"	"2.31"	"1"	"1"	"other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf00106"	"6697"	"ENSG00000116096"	"SPR"	"A8K741; D6W5H2; hsa:6697; P35270; Q53GI9; Q9UBB1"	""	"eNOS activation; Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"	"2"	"0"	"12.7"	"9.1"	"13.5"	"7.9"	"10.6"	"12.2"	"14.1"	"39.7"	"30.5"	"120.3"	"254.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NR12"	"PDZ and LIM domain protein 7 OS=Homo sapiens OX=9606 GN=PDLIM7 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"457"	"49.8"	"8.41"	"302.99"	"2.31"	"1"	"1"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412, Pf00595"	"9260"	"ENSG00000196923"	"PDLIM7"	"hsa:9260; Q14250; Q5XG82; Q6NVZ5; Q96C91; Q9BXB8; Q9BXB9; Q9NR12"	"Ebstein-Barr virus LMP1 signaling; GDNF signaling; 5q35 copy number variation"	"RET signaling"	"4"	"0"	"60.0"	"49.6"	"62.0"	"52.1"	"52.9"	"65.4"	"78.1"	"92.6"	"114.5"	"219.2"	"273.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H582"	"Zinc finger protein 644 OS=Homo sapiens OX=9606 GN=ZNF644 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1327"	"149.5"	"8.16"	"293.98"	"2.31"	"1"	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	""	"84146"	"ENSG00000122482"	"ZNF644"	"A2RU71; hsa:84146; Q2TAM0; Q5TCC0; Q6BEP7; Q6P446; Q6PI06; Q7LG67; Q9H582; Q9ULJ9"	""	""	"0"	"0"	"63.9"	"63.3"	"61.0"	"59.3"	"53.7"	"49.1"	"58.4"	"64.1"	"63.3"	"74.3"	"81.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UM54"	"Unconventional myosin-VI OS=Homo sapiens OX=9606 GN=MYO6 PE=1 SV=4"	"0.000"	""	"1"	"1"	"2"	"1"	"1294"	"149.6"	"8.53"	"256.24"	"2.31"	"1"	"1"	"cell organization and biogenesis;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00063, Pf16521"	"4646"	"ENSG00000196586"	"MYO6"	"A6H8V4; E1P540; hsa:4646; Q5TEM5; Q5TEM6; Q5TEM7; Q9BZZ7; Q9UEG2; Q9UM54"	"VEGFA-VEGFR2 signaling; Joubert syndrome"	"Gap junction degradation; RHOU GTPase cycle; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle; Trafficking of AMPA receptors"	"7"	"0"	"17.8"	"17.0"	"22.5"	"23.8"	"25.2"	"18.3"	"25.3"	"50.4"	"44.3"	"74.5"	"84.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5T160"	"Probable arginine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=RARS2 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"578"	"65.5"	"8.21"	"246.14"	"2.31"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00750, Pf05746"	"57038"	"ENSG00000146282"	"RARS2"	"B2RDT7; hsa:57038; Q5T160; Q96FU5; Q9H8K8"	""	"Mitochondrial tRNA aminoacylation"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y673"	"Dolichyl-phosphate beta-glucosyltransferase OS=Homo sapiens OX=9606 GN=ALG5 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"324"	"36.9"	"9.28"	"256.29"	"2.31"	"1"	"1"	"protein metabolism;other metabolic processes;developmental processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf00535"	"29880"	"ENSG00000120697"	"ALG5"	"B4DR37; hsa:29880; Q5TBA6; Q9Y673"	"N-glycan biosynthesis"	"Synthesis of dolichyl-phosphate-glucose"	"2"	"0"	"10.3"	"2.8"	"10.0"	"8.7"	"5.4"	"8.4"	"11.8"	"47.2"	"46.4"	"142.4"	"184.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NS91"	"E3 ubiquitin-protein ligase RAD18 OS=Homo sapiens OX=9606 GN=RAD18 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"495"	"56.2"	"7.58"	""	"2.31"	""	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02037, Pf13923"	"56852"	"ENSG00000070950"	"RAD18"	"hsa:56852; Q58F55; Q9NRT6; Q9NS91"	"SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome"	"Recognition of DNA damage by PCNA-containing replication complex; E3 ubiquitin ligases ubiquitinate target proteins"	"3"	"0"	"138.0"	"84.9"	"118.3"	"127.1"	"116.7"	"102.2"	"144.3"	"246.0"	"218.8"	"334.9"	"431.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9BYV8"	"Centrosomal protein of 41 kDa OS=Homo sapiens OX=9606 GN=CEP41 PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"373"	"41.3"	"8.32"	""	"2.30"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport"	"cytosol;cytoskeleton;other cell component"	""	"Pf00581"	"95681"	"ENSG00000106477"	"CEP41"	"A4D1M0; B4DQ35; F5H0V6; hsa:95681; Q7Z496; Q86TM1; Q8NFU8; Q9BYV8; Q9H6A3; Q9NPV3"	"Joubert syndrome; Ciliopathies; Bardet-Biedl syndrome"	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"10"	"0"	"11.0"	"11.6"	"19.6"	"17.0"	"15.0"	"14.1"	"15.2"	"33.1"	"32.2"	"71.6"	"90.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96MN5"	"Transcription elongation factor A N-terminal and central domain-containing protein 2 OS=Homo sapiens OX=9606 GN=TCEANC2 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"208"	"24.1"	"10.05"	"309.15"	"2.30"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf08711"	"127428"	"ENSG00000116205"	"TCEANC2"	"hsa:127428; Q5T702; Q8N8N2; Q96MN5"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8NE18"	"Putative methyltransferase NSUN7 OS=Homo sapiens OX=9606 GN=NSUN7 PE=2 SV=4"	""	""	"1"	"1"	"1"	"1"	"718"	"81.0"	"8.75"	""	"2.30"	""	"1"	"other metabolic processes"	""	"nucleic acid binding activity;other molecular function"	"Pf01189"	"79730"	"ENSG00000179299"	"NSUN7"	"C9JI19; hsa:79730; Q8N9K8; Q8NE18; Q9H815"	""	""	"0"	"0"	"48.1"	"15.0"	"84.9"	"46.7"	"49.1"	"52.8"	"87.9"	"535.2"	"577.6"	"1755.4"	"1488.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NFT6"	"Protein DBF4 homolog B OS=Homo sapiens OX=9606 GN=DBF4B PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"615"	"67.2"	"8.34"	"273.46"	"2.30"	"1"	"1"	"cell cycle OR cell proliferation;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf07535"	"80174"	"ENSG00000161692"	"DBF4B"	"D3DX56; hsa:80174; Q8NFT6; Q8TEX0; Q96B19; Q9H912"	""	""	"0"	"0"	"63.6"	"53.8"	"58.8"	"56.0"	"50.1"	"71.9"	"78.9"	"222.9"	"216.7"	"657.2"	"1125.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P31323"	"cAMP-dependent protein kinase type II-beta regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2B PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"418"	"46.3"	"4.92"	"252.25"	"2.29"	"1"	"1"	"other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00027, Pf02197"	"5577"	"ENSG00000005249; ENSG00000284096"	"PRKAR2B"	"A4D0R9; hsa:5577; P31323"	"Myometrial relaxation and contraction pathways; G protein signaling pathways; Cannabinoid receptor signaling; Lipid metabolism pathway; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"FCGR3A-mediated IL10 synthesis; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production; Factors involved in megakaryocyte development and platelet production; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Vasopressin regulates renal water homeostasis via Aquaporins; PKA activation; PKA activation in glucagon signalling; Hedgehog 'off' state; DARPP-32 events; CREB1 phosphorylation through the activation of Adenylate Cyclase"	"26"	"0"	"135.1"	"113.0"	"136.7"	"120.0"	"115.3"	"102.4"	"153.3"	"290.4"	"277.4"	"763.5"	"1135.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14777"	"Kinetochore protein NDC80 homolog OS=Homo sapiens OX=9606 GN=NDC80 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"642"	"73.9"	"5.60"	"361.73"	"2.29"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf03801, Pf18077"	"10403"	"ENSG00000080986"	"NDC80"	"hsa:10403; O14777; Q6PJX2"	""	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"6"	"0"	"5.2"	"3.6"	"6.1"	"6.9"	"7.4"	"9.9"	"10.4"	"12.3"	"13.2"	"33.3"	"21.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09001"	"39S ribosomal protein L3, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL3 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"348"	"38.6"	"9.48"	"284.61"	"2.29"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00297"	"11222"	"ENSG00000114686"	"MRPL3"	"hsa:11222; P09001; Q6IBT2"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"74.7"	"52.1"	"86.6"	"71.6"	"58.6"	"66.5"	"96.1"	"206.2"	"205.6"	"672.3"	"1208.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N9R8"	"Protein SCAI OS=Homo sapiens OX=9606 GN=SCAI PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"606"	"70.4"	"8.60"	"266.36"	"2.29"	"1"	"1"	"other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf12070"	"286205"	"ENSG00000173611"	"SCAI"	"hsa:286205; Q3SXZ1; Q3SXZ2; Q5T163; Q8N1I4; Q8N9R8"	""	"RHO GTPases Activate Formins"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00203"	"AP-3 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP3B1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1094"	"121.2"	"6.04"	"300.63"	"2.28"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01602, Pf14796, Pf14797"	"8546"	"ENSG00000132842"	"AP3B1"	"E5RJ68; hsa:8546; O00203; O00580; Q7Z393; Q9HD66"	""	"Golgi Associated Vesicle Biogenesis; Signaling by BRAF and RAF1 fusions"	"2"	"0"	"3.1"	"1.9"	"4.1"	"3.9"	"2.3"	"1.7"	"6.0"	"11.8"	"13.4"	"54.6"	"96.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z5K2"	"Wings apart-like protein homolog OS=Homo sapiens OX=9606 GN=WAPL PE=1 SV=1"	"0.000"	""	"2"	"2"	"2"	"2"	"1190"	"132.9"	"5.44"	"320.89"	"2.27"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf07814"	"23063"	"ENSG00000062650"	"WAPL"	"A7E2B5; hsa:23063; Q5VSK5; Q7Z5K2; Q8IX10; Q92549"	"Cohesin complex - Cornelia de Lange syndrome; 10q22q23 copy number variation"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"6"	"0"	"68.0"	"49.8"	"61.8"	"47.1"	"44.5"	"52.1"	"54.0"	"67.2"	"77.8"	"152.5"	"235.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UMY1"	"Nucleolar protein 7 OS=Homo sapiens OX=9606 GN=NOL7 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"257"	"29.4"	"9.67"	""	"2.27"	""	"1"	"other biological processes"	"mitochondrion;nucleus;other cell component"	""	"Pf08157"	"51406"	"ENSG00000225921"	"NOL7"	"hsa:51406; Q5T297; Q9UMY1; Q9Y3U7"	""	""	"0"	"0"	"63.3"	"62.9"	"74.5"	"73.2"	"63.5"	"71.5"	"92.2"	"152.3"	"160.5"	"457.5"	"576.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P06746"	"DNA polymerase beta OS=Homo sapiens OX=9606 GN=POLB PE=1 SV=3"	"0.000"	""	"7"	"2"	"3"	"2"	"335"	"38.2"	"8.95"	"528.95"	"2.27"	"2"	"1"	"DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf10391, Pf14716, Pf14791, Pf14792"	"5423"	"ENSG00000070501"	"POLB"	"B2RC78; hsa:5423; P06746; Q3KP48; Q6FI34"	"Male infertility; Base excision repair; DNA repair pathways, full network"	"Ub-specific processing proteases; APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway; POLB-Dependent Long Patch Base Excision Repair; PCNA-Dependent Long Patch Base Excision Repair; Abasic sugar-phosphate removal via the single-nucleotide replacement pathway"	"10"	"0"	"24.5"	"18.2"	"36.4"	"26.7"	"25.8"	"23.3"	"39.4"	"164.1"	"164.5"	"214.5"	"192.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y605"	"MORF4 family-associated protein 1 OS=Homo sapiens OX=9606 GN=MRFAP1 PE=1 SV=1"	"0.000"	""	"8"	"1"	"2"	"1"	"127"	"14.6"	"4.70"	"387.56"	"2.27"	"1"	"1"	""	"nucleus;other cell component"	""	"Pf15155"	"93621"	"ENSG00000179010"	"MRFAP1"	"B3KVT2; D3DVT3; hsa:93621; Q9Y605"	""	""	"0"	"0"	"131.0"	"105.2"	"112.2"	"126.6"	"101.8"	"100.7"	"140.1"	"177.3"	"200.2"	"301.4"	"344.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96BT3"	"Centromere protein T OS=Homo sapiens OX=9606 GN=CENPT PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"561"	"60.4"	"6.58"	"319.26"	"2.27"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf15511, Pf16171"	"80152"	"ENSG00000102901"	"CENPT"	"hsa:80152; Q96BT3; Q96I29; Q96IC6; Q96NK9; Q9H901"	""	"Resolution of Sister Chromatid Cohesion; Separation of Sister Chromatids; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Deposition of new CENPA-containing nucleosomes at the centromere"	"7"	"0"	"25.1"	"28.0"	"21.2"	"17.1"	"24.0"	"21.4"	"28.2"	"43.3"	"35.0"	"66.6"	"93.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TEW0"	"Partitioning defective 3 homolog OS=Homo sapiens OX=9606 GN=PARD3 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1356"	"151.3"	"7.68"	"283.56"	"2.26"	"1"	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00595, Pf12053"	"56288"	"ENSG00000148498"	"PARD3"	"F5H5T0; hsa:56288; Q5T2U1; Q5VUA2; Q5VUA3; Q5VWV0; Q5VWV1; Q5VWV3; Q5VWV4; Q5VWV5; Q6IQ47; Q8TCZ9; Q8TEW0; Q8TEW1; Q8TEW2; Q8TEW3; Q96K28; Q96RM6; Q96RM7; Q9BY57; Q9BY58; Q9HC48; Q9NWL4; Q9NYE6"	"Chemokine signaling pathway; Complement system in neuronal development and plasticity"	"Tight junction interactions; TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"	"4"	"0"	"90.0"	"50.9"	"95.0"	"83.3"	"82.5"	"75.5"	"98.2"	"142.7"	"141.8"	"341.0"	"425.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46779"	"60S ribosomal protein L28 OS=Homo sapiens OX=9606 GN=RPL28 PE=1 SV=3"	"0.000"	""	"5"	"1"	"2"	"1"	"137"	"15.7"	"12.02"	"313.90"	"2.26"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01778"	"6158"	"ENSG00000108107"	"RPL28"	"B2R4A6; B4DEP9; C9JB50; E9PB24; G5E9L2; hsa:6158; P46779; Q6IAY0; Q96FX1; Q9BWQ0"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis"	"14"	"0"	"110.1"	"92.4"	"110.1"	"93.5"	"83.7"	"112.3"	"148.1"	"237.9"	"211.1"	"595.1"	"1036.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q68EM7"	"Rho GTPase-activating protein 17 OS=Homo sapiens OX=9606 GN=ARHGAP17 PE=1 SV=1"	""	""	"1"	"1"	"1"	"1"	"881"	"95.4"	"7.62"	""	"2.26"	""	"1"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00620, Pf03114"	"55114"	"ENSG00000140750; ENSG00000288353"	"ARHGAP17"	"A8K6M6; hsa:55114; Q68EM7; Q6ZUS4; Q7Z2F2; Q8NDG2; Q96KS2; Q96KS3; Q96SS8; Q9BVF6; Q9H8U5; Q9NW54"	""	"CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOD GTPase cycle"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P49748"	"Very long-chain specific acyl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ACADVL PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"655"	"70.3"	"8.75"	""	"2.25"	""	"1"	"other metabolic processes;stress response;other biological processes"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf00441, Pf02770, Pf02771"	"37"	"ENSG00000072778"	"ACADVL"	"B4DEB6; F5H2A9; hsa:37; O76056; P49748; Q8WUL0"	"Fatty acid beta-oxidation; Mitochondrial long chain fatty acid beta-oxidation"	"XBP1(S) activates chaperone genes; Beta oxidation of palmitoyl-CoA to myristoyl-CoA"	"4"	"0"	"85.6"	"55.0"	"67.0"	"58.3"	"65.2"	"53.2"	"89.6"	"115.8"	"100.7"	"153.4"	"247.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00401"	"Neural Wiskott-Aldrich syndrome protein OS=Homo sapiens OX=9606 GN=WASL PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"505"	"54.8"	"7.93"	"263.23"	"2.25"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity"	"Pf00568, Pf00786, Pf02205"	"8976"	"ENSG00000106299"	"WASL"	"A1JUI9; hsa:8976; O00401; Q7Z746"	"Pathogenic Escherichia coli infection; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; Chemokine signaling pathway; G13 signaling pathway"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RHO GTPases Activate WASPs and WAVEs; RHOJ GTPase cycle; RHOV GTPase cycle; Clathrin-mediated endocytosis; NOSTRIN mediated eNOS trafficking; Nephrin family interactions; EPHB-mediated forward signaling; DCC mediated attractive signaling"	"17"	"0"	"106.6"	"87.1"	"89.4"	"100.0"	"102.3"	"107.1"	"124.0"	"149.3"	"169.9"	"298.9"	"339.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NPA8"	"Transcription and mRNA export factor ENY2 OS=Homo sapiens OX=9606 GN=ENY2 PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"101"	"11.5"	"9.33"	"284.17"	"2.25"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf10163"	"56943"	"ENSG00000120533"	"ENY2"	"B2RE52; G3V117; hsa:56943; Q9NPA8"	""	"HATs acetylate histones"	"1"	"0"	"100.2"	"89.9"	"102.6"	"97.5"	"85.6"	"86.5"	"113.1"	"237.0"	"210.9"	"489.0"	"626.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5SVZ6"	"Zinc finger MYM-type protein 1 OS=Homo sapiens OX=9606 GN=ZMYM1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"3"	"1"	"1142"	"128.6"	"7.44"	"566.34"	"2.25"	"1"	"1"	""	"nucleus"	"other molecular function"	"Pf05699, Pf06467, Pf14291"	"79830"	"ENSG00000197056"	"ZMYM1"	"D3DPR7; hsa:79830; Q5SVZ6; Q7Z3Q4"	""	""	"0"	"0"	"4.8"	"3.9"	"5.6"	"4.1"	"4.6"	"4.9"	"7.0"	"12.6"	"19.4"	"45.6"	"57.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q08AD1"	"Calmodulin-regulated spectrin-associated protein 2 OS=Homo sapiens OX=9606 GN=CAMSAP2 PE=1 SV=3"	"0.001"	""	"1"	"2"	"2"	"2"	"1489"	"168.0"	"6.80"	"234.33"	"2.25"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;ER/Golgi"	"cytoskeletal activity;other molecular function"	"Pf08683, Pf11971, Pf17095"	"23271"	"ENSG00000118200"	"CAMSAP2"	"B1APG6; hsa:23271; Q08AD1; Q08AD2; Q6PGN8; Q96FB3; Q9UG20; Q9UPS4"	""	""	"0"	"0"	"16.9"	"17.3"	"13.8"	"9.9"	"12.5"	"14.0"	"15.5"	"31.9"	"34.3"	"210.9"	"361.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BUT1"	"3-hydroxybutyrate dehydrogenase type 2 OS=Homo sapiens OX=9606 GN=BDH2 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"245"	"26.7"	"7.65"	"254.09"	"2.25"	"1"	"1"	"other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf13561"	"56898"	"ENSG00000164039"	"BDH2"	"A8K295; B4DUF6; hsa:56898; Q503A0; Q6IA46; Q6UWD3; Q9BUT1; Q9H8S8; Q9NRX8"	""	"Synthesis of Ketone Bodies"	"1"	"0"	"95.0"	"88.4"	"87.4"	"84.6"	"89.0"	"87.8"	"104.0"	"244.5"	"256.3"	"760.0"	"875.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60315"	"Zinc finger E-box-binding homeobox 2 OS=Homo sapiens OX=9606 GN=ZEB2 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1214"	"136.4"	"6.32"	"273.89"	"2.25"	"1"	"1"	"developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00096, Pf05605, Pf12874"	"9839"	"ENSG00000169554"	"ZEB2"	"A0JP09; B7Z2P2; F5H814; hsa:9839; O60315; Q9UED1"	"Mammary gland development pathway - Embryonic development (Stage 1 of 4); Epithelial to mesenchymal transition in colorectal cancer; TGF-beta receptor signaling in skeletal dysplasias; CCL18 signaling pathway; Extrafollicular and follicular B cell activation by SARS-CoV-2; A network map of Macrophage-stimulating protein (MSP) signaling; TGF-beta receptor signaling"	"Regulation of CDH11 gene transcription"	"8"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07919"	"Cytochrome b-c1 complex subunit 6, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRH PE=1 SV=2"	"0.000"	""	"14"	"2"	"3"	"2"	"91"	"10.7"	"4.44"	"487.89"	"2.25"	"2"	"1"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf02320"	"7388"	"ENSG00000173660"	"UQCRH"	"B2R4V9; D3DQ18; hsa:7388; P07919; Q5TDF6; Q6LDB8; Q9BQ91"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex III assembly"	"Respiratory electron transport"	"4"	"0"	"347.6"	"269.5"	"286.5"	"285.8"	"276.0"	"253.6"	"346.4"	"449.1"	"475.4"	"752.8"	"926.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13033"	"Striatin-3 OS=Homo sapiens OX=9606 GN=STRN3 PE=1 SV=3"	"0.001"	""	"1"	"1"	"2"	"1"	"797"	"87.2"	"5.36"	"230.62"	"2.24"	"1"	"1"	"other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00400, Pf08232"	"29966"	"ENSG00000196792"	"STRN3"	"A2RTX7; A6NHZ7; hsa:29966; Q13033; Q9NRA5"	""	""	"0"	"0"	"82.2"	"67.1"	"77.2"	"71.7"	"73.3"	"78.4"	"96.7"	"156.0"	"165.3"	"393.5"	"505.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NRX2"	"39S ribosomal protein L17, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL17 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"175"	"20.0"	"10.11"	"252.70"	"2.24"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf01196"	"63875"	"ENSG00000158042"	"MRPL17"	"D3DQU3; hsa:63875; Q6IAH8; Q96Q53; Q9C066; Q9NRX2"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"63.0"	"41.2"	"68.5"	"63.0"	"63.0"	"58.4"	"75.0"	"106.7"	"117.9"	"270.1"	"415.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O60496"	"Docking protein 2 OS=Homo sapiens OX=9606 GN=DOK2 PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"412"	"45.4"	"6.02"	""	"2.24"	""	"1"	"signal transduction;other biological processes"	"cytosol;other cell component"	"signal transduction activity or receptor binding"	"Pf02174"	"9046"	"ENSG00000147443"	"DOK2"	"hsa:9046; O60496; Q8N5A4"	"RAC1/PAK1/p38/MMP2 pathway; IL-4 signaling pathway; EGF/EGFR signaling pathway"	"RET signaling; Tie2 Signaling"	"5"	"0"	"93.2"	"42.5"	"161.1"	"128.0"	"113.9"	"124.5"	"143.1"	"228.0"	"259.9"	"467.1"	"480.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9BS16"	"Centromere protein K OS=Homo sapiens OX=9606 GN=CENPK PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"269"	"31.6"	"4.89"	""	"2.24"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis"	"cytosol;nucleus;other cell component"	""	"Pf11802"	"64105"	"ENSG00000123219"	"CENPK"	"hsa:64105; Q9BS16; Q9H4L0"	""	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Deposition of new CENPA-containing nucleosomes at the centromere"	"7"	"0"	"10.1"	"5.9"	"10.9"	"12.2"	"5.4"	"18.5"	"21.0"	"49.8"	"47.4"	"117.4"	"178.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15417"	"Trinucleotide repeat-containing gene 18 protein OS=Homo sapiens OX=9606 GN=TNRC18 PE=1 SV=3"	"0.001"	""	"0"	"1"	"2"	"1"	"2968"	"314.3"	"8.70"	"234.96"	"2.23"	"1"	"1"	""	"other membranes;cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf01426"	"84629"	"ENSG00000182095"	"TNRC18"	"A8MX41; hsa:84629; O15417; Q96JH1; Q96K91"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q147X3"	"N-alpha-acetyltransferase 30 OS=Homo sapiens OX=9606 GN=NAA30 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"362"	"39.3"	"5.52"	"268.21"	"2.23"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00583"	"122830"	"ENSG00000139977"	"NAA30"	"hsa:122830; Q0IIN2; Q147X3"	"Metapathway biotransformation Phase I and II"	"Retrograde transport at the Trans-Golgi-Network"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P48681"	"Nestin OS=Homo sapiens OX=9606 GN=NES PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1621"	"177.3"	"4.36"	""	"2.23"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytoskeleton;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00038"	"10763"	"ENSG00000132688"	"NES"	"hsa:10763; O00552; P48681; Q3LIF5; Q5SYZ6"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P10619"	"Lysosomal protective protein OS=Homo sapiens OX=9606 GN=CTSA PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"480"	"54.4"	"6.61"	"275.84"	"2.22"	"1"	"1"	"protein metabolism;transport;other biological processes"	"non-structural extracellular;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00450"	"5476"	"ENSG00000064601"	"CTSA"	"B2R798; hsa:5476; P10619; Q561W6; Q5JZH1; Q96KJ2; Q9BR08; Q9BW68"	"Ciliary landscape"	"MHC class II antigen presentation; Glycosphingolipid metabolism; Neutrophil degranulation; Sialic acid metabolism; Defective NEU1 causes sialidosis"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9H4B0"	"Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OSGEPL1 PE=2 SV=2"	""	""	"1"	"1"	"1"	"1"	"414"	"45.1"	"8.56"	""	"2.22"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00814"	"64172"	"ENSG00000128694"	"OSGEPL1"	"hsa:64172; Q96EV9; Q96NH5; Q9H4B0"	""	""	"0"	"0"	"73.6"	"59.7"	"86.2"	"75.3"	"79.8"	"73.5"	"187.4"	"476.2"	"501.4"	"978.5"	"840.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H0B6"	"Kinesin light chain 2 OS=Homo sapiens OX=9606 GN=KLC2 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"622"	"68.9"	"7.15"	"251.68"	"2.22"	"1"	"1"	"other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity"	"Pf13424"	"64837"	"ENSG00000174996"	"KLC2"	"A8MXL7; B2RDY4; hsa:64837; Q9H0B6; Q9H9C8; Q9HA20"	"Alzheimer's disease and miRNA effects; Alzheimer's disease"	"MHC class II antigen presentation; RHO GTPases activate KTN1; COPI-dependent Golgi-to-ER retrograde traffic; Kinesins"	"6"	"0"	"53.1"	"53.5"	"54.3"	"57.2"	"48.6"	"54.6"	"59.5"	"162.1"	"168.5"	"414.4"	"486.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q16222"	"UDP-N-acetylhexosamine pyrophosphorylase OS=Homo sapiens OX=9606 GN=UAP1 PE=1 SV=3"	""	""	"2"	"1"	"1"	"1"	"522"	"58.7"	"6.33"	""	"2.22"	""	"1"	"other metabolic processes"	"plasma membrane;other membranes;cytosol;nucleus"	"other molecular function"	"Pf01704"	"6675"	"ENSG00000117143"	"UAP1"	"B2R6R8; hsa:6675; Q16222; Q5VTA9; Q5VTB0; Q5VTB1; Q96GM2"	""	"Synthesis of UDP-N-acetyl-glucosamine"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86WG5"	"Myotubularin-related protein 13 OS=Homo sapiens OX=9606 GN=SBF2 PE=1 SV=1"	"0.000"	""	"2"	"3"	"4"	"3"	"1849"	"208.3"	"7.06"	"809.88"	"2.22"	"3"	"1"	"other metabolic processes;developmental processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf02141, Pf02893, Pf03456, Pf06602, Pf12335"	"81846"	"ENSG00000133812"	"SBF2"	"hsa:81846; Q3MJF0; Q68DQ3; Q6P459; Q6PJD1; Q7Z325; Q7Z621; Q86VE2; Q86WG5; Q96FE2; Q9C097"	"Intracellular trafficking proteins involved in CMT neuropathy"	"RAB GEFs exchange GTP for GDP on RABs; Synthesis of PIPs at the plasma membrane"	"3"	"0"	"52.9"	"37.2"	"51.4"	"50.3"	"64.0"	"103.9"	"147.0"	"350.5"	"352.3"	"560.7"	"587.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q92624"	"Amyloid protein-binding protein 2 OS=Homo sapiens OX=9606 GN=APPBP2 PE=1 SV=2"	""	""	"4"	"1"	"1"	"1"	"585"	"66.8"	"6.90"	""	"2.22"	""	"1"	"protein metabolism;other metabolic processes;transport"	"other membranes;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf13374, Pf13424"	"10513"	"ENSG00000062725"	"APPBP2"	"A8K862; hsa:10513; O95095; Q8WVC9; Q92624"	""	""	"0"	"0"	"23.1"	"8.0"	"18.2"	"21.2"	"22.2"	"17.3"	"25.4"	"69.6"	"75.9"	"307.3"	"378.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96CN9"	"GRIP and coiled-coil domain-containing protein 1 OS=Homo sapiens OX=9606 GN=GCC1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"775"	"87.8"	"5.45"	"245.57"	"2.22"	"1"	"1"	""	"other membranes;cytosol;ER/Golgi"	"other molecular function"	"Pf01465"	"79571"	"ENSG00000179562"	"GCC1"	"hsa:79571; Q96CN9; Q9H6N7"	"Nuclear receptors meta-pathway"	"Retrograde transport at the Trans-Golgi-Network"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O14874"	"[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial OS=Homo sapiens OX=9606 GN=BCKDK PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"412"	"46.3"	"8.82"	""	"2.22"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"mitochondrion"	"kinase activity;other molecular function"	"Pf02518, Pf10436"	"10295"	"ENSG00000103507"	"BCKDK"	"A8MY43; hsa:10295; O14874; Q6FGL4; Q96G95; Q96IN5"	"Thiamine metabolic pathways"	"Branched-chain amino acid catabolism"	"2"	"0"	"29.0"	"26.2"	"32.3"	"33.3"	"28.5"	"35.4"	"37.7"	"60.0"	"59.7"	"129.4"	"158.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P18206"	"Vinculin OS=Homo sapiens OX=9606 GN=VCL PE=1 SV=4"	"0.000"	""	"1"	"1"	"2"	"1"	"1134"	"123.7"	"5.66"	"258.56"	"2.22"	"1"	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01044"	"7414"	"ENSG00000035403"	"VCL"	"hsa:7414; P18206; Q16450; Q5SWX2; Q7Z3B8; Q8IXU7"	"Integrin-mediated cell adhesion; Primary focal segmental glomerulosclerosis (FSGS); Focal adhesion; VEGFA-VEGFR2 signaling; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Melanoma; Regulation of actin cytoskeleton"	"Neutrophil degranulation; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Platelet degranulation ; Signaling by BRAF and RAF1 fusions; Signaling by ALK fusions and activated point mutants; Smooth Muscle Contraction; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants"	"18"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5W0B1"	"ORC ubiquitin ligase 1 OS=Homo sapiens OX=9606 GN=OBI1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"726"	"81.1"	"5.72"	"344.24"	"2.22"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other cell component"	"other molecular function"	"Pf13923"	"79596"	"ENSG00000152193"	"OBI1"	"B2RN99; hsa:79596; Q5W0B1; Q8TBY2; Q9H0T2; Q9H8M0"	""	""	"0"	"0"	"19.1"	"16.9"	"13.8"	"18.6"	"19.1"	"19.9"	"22.7"	"48.3"	"47.4"	"123.7"	"194.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9C0I1"	"Myotubularin-related protein 12 OS=Homo sapiens OX=9606 GN=MTMR12 PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"747"	"86.1"	"6.62"	""	"2.21"	""	"1"	"transport"	"cytosol;cytoskeleton;ER/Golgi;other cell component"	""	"Pf06602, Pf12578"	"54545"	"ENSG00000150712"	"MTMR12"	"hsa:54545; Q69YJ4; Q6PFW3; Q96QU2; Q9C0I1; Q9NX27"	""	"Synthesis of PIPs at the early endosome membrane"	"1"	"0"	"29.1"	"15.8"	"24.9"	"20.6"	"27.2"	"37.2"	"47.1"	"94.3"	"89.5"	"151.4"	"189.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99698"	"Lysosomal-trafficking regulator OS=Homo sapiens OX=9606 GN=LYST PE=1 SV=3"	"0.000"	""	"0"	"2"	"3"	"2"	"3801"	"428.9"	"6.61"	"495.64"	"2.21"	"2"	"1"	"cell organization and biogenesis;stress response;transport;other biological processes"	"other membranes;cytosol;cytoskeleton"	"other molecular function"	"Pf00400, Pf02138, Pf14844"	"1130"	"ENSG00000143669"	"LYST"	"hsa:1130; O43274; Q5T2U9; Q96TD7; Q96TD8; Q99698; Q99709; Q9H133"	""	""	"0"	"0"	"269.4"	"211.3"	"236.9"	"233.6"	"228.2"	"219.4"	"254.0"	"470.4"	"397.2"	"918.4"	"1312.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9BRX5"	"DNA replication complex GINS protein PSF3 OS=Homo sapiens OX=9606 GN=GINS3 PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"216"	"24.5"	"5.34"	""	"2.21"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"nucleus"	""	"Pf05916"	"64785"	"ENSG00000181938"	"GINS3"	"B2RDP3; E9PB21; hsa:64785; Q9BRX5; Q9H870"	""	"Unwinding of DNA"	"1"	"0"	"137.1"	"86.8"	"111.3"	"107.8"	"86.2"	"112.6"	"145.5"	"204.8"	"184.0"	"326.8"	"373.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86WW8"	"Cytochrome c oxidase assembly factor 5 OS=Homo sapiens OX=9606 GN=COA5 PE=1 SV=1"	"0.000"	""	"9"	"1"	"2"	"1"	"74"	"8.4"	"8.68"	"274.00"	"2.21"	"1"	"1"	"cell organization and biogenesis"	"mitochondrion"	""	"Pf10203"	"493753"	"ENSG00000183513"	"COA5"	"hsa:493753; Q86WW8"	""	""	"0"	"0"	"115.4"	"96.1"	"76.2"	"82.2"	"92.8"	"57.5"	"124.0"	"269.0"	"256.4"	"385.8"	"364.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P54687"	"Branched-chain-amino-acid aminotransferase, cytosolic OS=Homo sapiens OX=9606 GN=BCAT1 PE=1 SV=3"	""	""	"5"	"1"	"1"	"1"	"386"	"42.9"	"5.30"	""	"2.21"	""	"1"	"cell cycle OR cell proliferation;other metabolic processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf01063"	"586"	"ENSG00000060982"	"BCAT1"	"B3KY27; B7Z2M5; B7Z5L0; F5H5E4; hsa:586; P54687; Q68DQ7; Q96MY9"	"Trans-sulfuration, one-carbon metabolism and related pathways; Amino acid metabolism"	"Branched-chain amino acid catabolism"	"3"	"0"	"83.6"	"26.1"	"136.9"	"117.4"	"113.6"	"95.6"	"122.9"	"124.0"	"154.5"	"191.0"	"152.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9C0C9"	"(E3-independent) E2 ubiquitin-conjugating enzyme OS=Homo sapiens OX=9606 GN=UBE2O PE=1 SV=3"	""	""	"1"	"1"	"1"	"1"	"1292"	"141.2"	"5.12"	""	"2.20"	""	"1"	"protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00179"	"63893"	"ENSG00000175931"	"UBE2O"	"A6NDU5; hsa:63893; Q69YP4; Q6PIZ2; Q86UA4; Q8N425; Q8TBN1; Q9BSW1; Q9C0C9; Q9H6E6; Q9H7E4; Q9H9B2"	""	"Antigen processing: Ubiquitination & Proteasome degradation"	"1"	"0"	"122.5"	"99.0"	"119.7"	"115.1"	"103.4"	"106.7"	"134.6"	"204.6"	"174.8"	"390.9"	"550.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P30530"	"Tyrosine-protein kinase receptor UFO OS=Homo sapiens OX=9606 GN=AXL PE=1 SV=4"	""	""	"2"	"1"	"1"	"1"	"894"	"98.3"	"5.39"	""	"2.20"	""	"1"	"cell adhesion;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytoskeleton;other cell component"	"cytoskeletal activity;kinase activity;other molecular function"	"Pf00041, Pf07714, Pf13927"	"558"	"ENSG00000167601"	"AXL"	"hsa:558; P30530; Q8N5L2; Q9UD27"	"Ebola virus infection in host; EGFR tyrosine kinase inhibitor resistance; Complement system in neuronal development and plasticity"	"VEGFA-VEGFR2 Pathway"	"4"	"0"	"97.6"	"26.6"	"97.6"	"75.0"	"72.3"	"80.5"	"108.7"	"311.3"	"366.6"	"575.8"	"513.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H1K1"	"Iron-sulfur cluster assembly enzyme ISCU, mitochondrial OS=Homo sapiens OX=9606 GN=ISCU PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"167"	"18.0"	"9.48"	"239.99"	"2.20"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01592"	"23479"	"ENSG00000136003"	"ISCU"	"hsa:23479; Q6P713; Q99617; Q9H1K1; Q9H1K2"	"Iron-sulfur cluster biogenesis"	"Maturation of replicase proteins"	"2"	"0"	"92.2"	"55.1"	"86.0"	"87.7"	"87.0"	"94.2"	"94.8"	"171.8"	"171.8"	"304.5"	"326.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51965"	"Ubiquitin-conjugating enzyme E2 E1 OS=Homo sapiens OX=9606 GN=UBE2E1 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"193"	"21.4"	"8.53"	"284.42"	"2.20"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00179"	"7324"	"ENSG00000170142"	"UBE2E1"	"B2RBX4; C9J8K2; hsa:7324; K4DI90; P51965"	"Photodynamic therapy-induced unfolded protein response; 7q11.23 copy number variation syndrome"	"Assembly of the pre-replicative complex; Separation of Sister Chromatids; E3 ubiquitin ligases ubiquitinate target proteins; Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Antigen processing: Ubiquitination & Proteasome degradation; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; CDK-mediated phosphorylation and removal of Cdc6; ISG15 antiviral mechanism; Autodegradation of Cdh1 by Cdh1:APC/C; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of Cyclin B; Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase; Regulation of APC/C activators between G1/S and early anaphase; Phosphorylation of the APC/C; APC-Cdc20 mediated degradation of Nek2A; Senescence-Associated Secretory Phenotype (SASP); Transcriptional Regulation by VENTX; Aberrant regulation of mitotic exit in cancer due to RB1 defects"	"23"	"0"	"73.1"	"57.4"	"69.6"	"72.4"	"62.6"	"88.5"	"131.8"	"302.1"	"272.3"	"748.8"	"911.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8IXI2"	"Mitochondrial Rho GTPase 1 OS=Homo sapiens OX=9606 GN=RHOT1 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"618"	"70.7"	"6.27"	""	"2.20"	""	"1"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf00071, Pf08355, Pf08356"	"55288"	"ENSG00000126858"	"RHOT1"	"A4FVB6; A6NFV0; B4DG48; hsa:55288; J9JIH9; Q6NUR3; Q6P9F8; Q6PJG1; Q6YMW8; Q86UB0; Q8IW28; Q8IXI2; Q8IXJ7; Q9H067; Q9H9N8; Q9NUZ2"	""	"Ub-specific processing proteases; RHOT1 GTPase cycle"	"2"	"0"	"33.1"	"22.0"	"45.9"	"41.2"	"42.8"	"41.2"	"44.2"	"82.3"	"93.9"	"202.4"	"247.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13233"	"Mitogen-activated protein kinase kinase kinase 1 OS=Homo sapiens OX=9606 GN=MAP3K1 PE=1 SV=4"	"0.000"	""	"1"	"1"	"2"	"1"	"1512"	"164.4"	"7.74"	"284.02"	"2.20"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"4214"	"ENSG00000095015"	"MAP3K1"	"hsa:4214; Q13233"	"IL-1 signaling pathway; TNF-alpha signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Apoptosis; Interleukin-1 (IL-1) structural pathway; Cardiac hypertrophic response; Fas ligand pathway and stress induction of heat shock proteins; MAPK signaling pathway; Apoptosis modulation by HSP70; Novel intracellular components of RIG-I-like receptor pathway; Angiopoietin-like protein 8 regulatory pathway; BMP signaling in eyelid development; Oxidative damage response; p38 MAPK signaling pathway; MAPK cascade; EGF/EGFR signaling pathway; Vitamin D in inflammatory diseases; Signal transduction through IL1R; Hepatitis B infection; Insulin signaling; MAP3K1 role in promoting and blocking gonadal determination; Host-pathogen interaction of human coronaviruses - MAPK signaling; Pleural mesothelioma; Interferon type I signaling pathways; DNA damage response (only ATM dependent); Serotonin HTR1 group and FOS pathway"	"FCERI mediated MAPK activation; MyD88:MAL(TIRAP) cascade initiated on plasma membrane; TRAF6 mediated NF-kB activation; TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation; MyD88 cascade initiated on plasma membrane"	"31"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43150"	"Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ASAP2 PE=1 SV=3"	"0.001"	""	"1"	"1"	"2"	"1"	"1006"	"111.6"	"6.68"	"235.98"	"2.20"	"1"	"1"	"other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi"	"enzyme regulator activity;other molecular function"	"Pf00023, Pf00169, Pf01412, Pf14604, Pf16746"	"8853"	"ENSG00000151693"	"ASAP2"	"D6W4Y8; hsa:8853; O43150"	"Vitamin D receptor pathway"	""	"1"	"0"	"0.0"	"0.0"	"8.7"	"5.5"	"3.6"	"3.4"	"5.4"	"11.5"	"9.6"	"47.3"	"73.5"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P28482"	"Mitogen-activated protein kinase 1 OS=Homo sapiens OX=9606 GN=MAPK1 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"360"	"41.4"	"6.98"	"240.67"	"2.20"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00069"	"5594"	"ENSG00000100030"	"MAPK1"	"A8CZ64; hsa:5594; P28482"	"IL-5 signaling pathway; Osteopontin signaling; Physiological and pathological hypertrophy of the heart; Angiogenesis; MicroRNAs in cardiomyocyte hypertrophy; Type II diabetes mellitus; Heart development; Integrin-mediated cell adhesion; IL-1 signaling pathway; Thyroxine (thyroid hormone) production; RANKL/RANK signaling pathway; Thyroid stimulating hormone (TSH) signaling pathway; Leptin signaling pathway; Follicle stimulating hormone (FSH) signaling pathway; TNF-related weak inducer of apoptosis (TWEAK) signaling pathway; Prolactin signaling pathway; IL-7 signaling pathway; Alzheimer's disease and miRNA effects; IL-17 signaling pathway; Endothelin pathways; IL-9 signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; Glioblastoma signaling pathways; Androgen receptor network in prostate cancer; B cell receptor signaling pathway; TNF-alpha signaling pathway; AGE/RAGE pathway; Interleukin-11 signaling pathway; Corticotropin-releasing hormone signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Spinal cord injury; Alpha 6 beta 4 signaling pathway; PDGF pathway; Aryl hydrocarbon receptor pathway; S1P receptor signal transduction; Ebstein-Barr virus LMP1 signaling; Common pathways underlying drug addiction; Interleukin-1 (IL-1) structural pathway; Cardiac hypertrophic response; Bladder cancer; IL-3 signaling pathway; Apoptosis-related network due to altered Notch3 in ovarian cancer; TCA cycle nutrient use and invasiveness of ovarian cancer; Kit receptor signaling pathway; Focal adhesion; Hepatocyte growth factor receptor signaling; MFAP5-mediated ovarian cancer cell motility and invasiveness; RAC1/PAK1/p38/MMP2 pathway; Wnt signaling pathway; IL6 signaling pathway; Hypothesized pathways in pathogenesis of cardiovascular disease; BDNF-TrkB signaling; Physico-chemical features and toxicity-associated pathways; MAPK signaling pathway; MAPK and NFkB signaling pathways inhibited by Yersinia YopJ; ERK pathway in Huntington's disease; Toll-like receptor signaling related to MyD88; TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition; 4-hydroxytamoxifen, dexamethasone, and retinoic acids regulation of p27 expression; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Chemokine signaling pathway; Embryonic stem cell pluripotency pathways; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; IL-4 signaling pathway; Prion disease pathway; Endometrial cancer; PI3K-Akt signaling pathway; Chromosomal and microsatellite instability in colorectal cancer ; Ebola virus infection in host; MAPK cascade; Ras signaling; Epithelial to mesenchymal transition in colorectal cancer; Non-small cell lung cancer; Breast cancer pathway; Pancreatic adenocarcinoma pathway; Acute viral myocarditis; Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells; Neovascularisation processes; Non-genomic actions of 1,25 dihydroxyvitamin D3; EGF/EGFR signaling pathway; Bile acids synthesis and enterohepatic circulation ; Resistin as a regulator of inflammation; Relationship between inflammation, COX-2 and EGFR; Envelope proteins and their potential roles in EDMD physiopathology; Regulatory circuits of the STAT3 signaling pathway; Synaptic signaling pathways associated with autism spectrum disorder; Fragile X syndrome; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Translation inhibitors in chronically activated PDGFRA cells; Gastrin signaling pathway; Hepatitis B infection; Melanoma; Netrin-UNC5B signaling pathway; IL-18 signaling pathway; FGFR3 signaling in chondrocyte proliferation and terminal differentiation; Osteoblast differentiation and related diseases; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; Regucalcin in proximal tubule epithelial kidney cells; Kisspeptin/kisspeptin receptor system in the ovary; MAP3K1 role in promoting and blocking gonadal determination; CAMKK2 pathway; Disruption of postsynaptic signaling by CNV; Host-pathogen interaction of human coronaviruses - MAPK signaling; IL-2 signaling pathway; RAS and bradykinin pathways in COVID-19; Angiotensin II receptor type 1 pathway; Kallmann syndrome; Neuroinflammation and glutamatergic signaling; Pleural mesothelioma; Orexin receptor pathway; CCL18 signaling pathway; Regulation of actin cytoskeleton; Sphingolipid metabolism in senescence; Alzheimer's disease; Th17 cell differentiation pathway; GDNF signaling; 2q11.2 copy number variation syndrome; 2q13 copy number variation syndrome; Hippocampal synaptogenesis and neurogenesis; Comprehensive IL-17A signaling; Genetic causes of porto-sinusoidal vascular disease; Female steroid hormones in cardiomyocyte energy metabolism; Cardiomyocyte signaling pathways converging on Titin; 8p23.1 copy number variation syndrome; IL-26 signaling pathways; A network map of Macrophage-stimulating protein (MSP) signaling; 4p16.3 copy number variation; Role of hypoxia, angiogenesis, and FGF pathway in OA chondrocyte hypertrophy; NPHP1 deletion syndrome; EPO receptor signaling; ErbB signaling pathway; T-cell receptor signaling pathway; DNA damage response (only ATM dependent); Estrogen signaling pathway; Vitamin A and carotenoid metabolism; Toll-like receptor signaling pathway"	"NPAS4 regulates expression of target genes; Estrogen-dependent nuclear events downstream of ESR-membrane signaling; Recycling pathway of L1; Downregulation of SMAD2/3:SMAD4 transcriptional activity; Neutrophil degranulation; Regulation of actin dynamics for phagocytic cup formation; FCERI mediated MAPK activation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Regulation of HSF1-mediated heat shock response; Signaling by BRAF and RAF1 fusions; Thrombin signalling through proteinase activated receptors (PARs); SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Oxidative Stress Induced Senescence; Regulation of PTEN gene transcription; Signaling by NODAL; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Interferon gamma signaling; Oncogene Induced Senescence; Senescence-Associated Secretory Phenotype (SASP); Growth hormone receptor signaling; Regulation of the apoptosome activity; Signal transduction by L1; NCAM signaling for neurite out-growth; RUNX2 regulates osteoblast differentiation; RSK activation; Estrogen-stimulated signaling through PRKCZ; Spry regulation of FGF signaling; Suppression of apoptosis; MAPK1 (ERK2) activation; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; IFNG signaling activates MAPKs; Golgi Cisternae Pericentriolar Stack Reorganization; Signaling by Activin; Activation of the AP-1 family of transcription factors; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; Frs2-mediated activation; Signal attenuation; Gastrin-CREB signalling pathway via PKC and MAPK; Nuclear events stimulated by ALK signaling in cancer; ESR-mediated signaling; Negative feedback regulation of MAPK pathway; Advanced glycosylation endproduct receptor signaling; RHO GTPases Activate NADPH Oxidases; ERKs are inactivated; Signaling by MAP2K mutants; phospho-PLA2 pathway; Signaling by MAPK mutants"	"200"	"0"	"81.7"	"52.2"	"89.2"	"73.7"	"72.6"	"84.9"	"110.7"	"259.0"	"242.0"	"498.6"	"664.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q53GQ0"	"Very-long-chain 3-oxoacyl-CoA reductase OS=Homo sapiens OX=9606 GN=HSD17B12 PE=1 SV=2"	""	""	"4"	"1"	"1"	"1"	"312"	"34.3"	"9.32"	""	"2.19"	""	"1"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"extracellular matrix;other membranes;ER/Golgi"	"other molecular function"	"Pf00106"	"51144"	"ENSG00000149084"	"HSD17B12"	"A8K9B0; D3DR23; hsa:51144; Q53GQ0; Q96EA9; Q96JU2; Q9Y6G8"	"Mitochondrial fatty acid synthesis pathway"	"Synthesis of very long-chain fatty acyl-CoAs; Androgen biosynthesis"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9H6T0"	"Epithelial splicing regulatory protein 2 OS=Homo sapiens OX=9606 GN=ESRP2 PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"727"	"78.4"	"6.71"	""	"2.19"	""	"1"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	""	"80004"	"ENSG00000103067"	"ESRP2"	"hsa:80004; Q8N6H8; Q8WZ15; Q9H6I4; Q9H6T0"	""	"FGFR2 alternative splicing"	"1"	"0"	"114.4"	"100.6"	"113.1"	"108.3"	"92.6"	"107.1"	"135.4"	"156.7"	"166.1"	"259.0"	"330.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NI36"	"WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"951"	"105.3"	"7.53"	"249.54"	"2.19"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf00400, Pf04192, Pf12894"	"134430"	""	"WDR36"	"A2RUS4; hsa:134430; Q68E02; Q8N1Q2; Q8NI36"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"9.2"	"3.5"	"8.0"	"7.7"	"5.3"	"7.7"	"9.9"	"15.4"	"13.2"	"34.9"	"48.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13439"	"Golgin subfamily A member 4 OS=Homo sapiens OX=9606 GN=GOLGA4 PE=1 SV=1"	"0.001"	""	"0"	"1"	"2"	"1"	"2230"	"261.0"	"5.39"	"235.32"	"2.19"	"1"	"1"	"cell organization and biogenesis;transport"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf01465"	"2803"	"ENSG00000144674"	"GOLGA4"	"F8W8Q7; hsa:2803; Q13270; Q13439; Q13654; Q14436; Q59EW8"	""	"Retrograde transport at the Trans-Golgi-Network; Signaling by membrane-tethered fusions of PDGFRA or PDGFRB"	"2"	"0"	"6.8"	"5.5"	"5.7"	"6.7"	"8.6"	"9.8"	"19.1"	"26.5"	"33.4"	"33.7"	"55.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NI08"	"Nuclear receptor coactivator 7 OS=Homo sapiens OX=9606 GN=NCOA7 PE=1 SV=2"	"0.000"	""	"3"	"2"	"3"	"2"	"942"	"106.1"	"5.59"	"546.43"	"2.19"	"2"	"1"	"stress response;other biological processes"	"nucleus"	"other molecular function"	"Pf01476, Pf07534"	"135112"	"ENSG00000111912"	"NCOA7"	"B2RNS2; B7Z2C4; B9EH71; G8JL91; hsa:135112; Q3LID6; Q4G0V1; Q5TF95; Q6IPQ4; Q6NE83; Q86T89; Q8N1W4; Q8NI08"	"Aryl hydrocarbon receptor pathway"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13617"	"Cullin-2 OS=Homo sapiens OX=9606 GN=CUL2 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"745"	"86.9"	"6.92"	"256.08"	"2.18"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;signal transduction"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00888, Pf10557"	"8453"	"ENSG00000108094"	"CUL2"	"B3KT95; B7Z6K8; D3DRY6; G3V1S2; hsa:8453; O00200; Q13617; Q5T2B6; Q9UNF9"	"Type 2 papillary renal cell carcinoma; Hijack of ubiquitination by SARS-CoV-2"	"Neddylation; Regulation of expression of SLITs and ROBOs; Antigen processing: Ubiquitination & Proteasome degradation; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"	"6"	"0"	"15.6"	"16.1"	"17.8"	"21.5"	"18.9"	"16.0"	"23.3"	"68.8"	"84.3"	"323.8"	"603.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92989"	"Polyribonucleotide 5'-hydroxyl-kinase Clp1 OS=Homo sapiens OX=9606 GN=CLP1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"425"	"47.6"	"6.62"	"261.91"	"2.18"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus"	"kinase activity;other molecular function"	"Pf06807, Pf16573, Pf16575"	"10978"	"ENSG00000172409"	"CLP1"	"B2R7J6; B4DTI8; hsa:10978; Q92989"	"mRNA processing"	"tRNA processing in the nucleus; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"6"	"0"	"13.7"	"10.9"	"12.8"	"11.8"	"14.9"	"8.5"	"13.1"	"24.3"	"22.8"	"51.8"	"66.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9BPX3"	"Condensin complex subunit 3 OS=Homo sapiens OX=9606 GN=NCAPG PE=1 SV=1"	""	""	"1"	"1"	"1"	"1"	"1015"	"114.3"	"5.59"	""	"2.18"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf12719"	"64151"	"ENSG00000109805"	"NCAPG"	"hsa:64151; Q3MJE0; Q96SV9; Q9BPX3; Q9BUR3; Q9BVY1; Q9H914; Q9H9Z6; Q9HBI9"	""	"Condensation of Prometaphase Chromosomes"	"1"	"0"	"103.5"	"66.5"	"89.4"	"108.2"	"93.7"	"93.5"	"105.6"	"227.6"	"243.2"	"497.2"	"558.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15504"	"Nucleoporin NUP42 OS=Homo sapiens OX=9606 GN=NUP42 PE=1 SV=1"	"0.000"	""	"5"	"2"	"2"	"2"	"423"	"44.8"	"9.19"	"348.14"	"2.18"	"1"	"1"	"transport"	"other membranes;cytosol;nucleus"	"other molecular function"	""	"11097"	"ENSG00000136243"	"NUP42"	"A4D143; B4DP42; hsa:11097; O15504; Q49AE7; Q9BS49"	""	"HCMV Late Events; HCMV Early Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"28"	"0"	"86.7"	"87.7"	"89.0"	"89.9"	"91.7"	"73.4"	"108.5"	"154.6"	"146.3"	"319.0"	"438.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NWW7"	"Uncharacterized protein C2orf42 OS=Homo sapiens OX=9606 GN=C2orf42 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"574"	"64.0"	"8.92"	"254.60"	"2.18"	"1"	"1"	""	"nucleus"	""	"Pf14952"	"54980"	"ENSG00000115998"	"C2orf42"	"D6W5G3; hsa:54980; Q9H629; Q9NWW7"	""	""	"0"	"0"	"222.7"	"59.6"	"388.0"	"263.3"	"266.6"	"284.1"	"295.6"	"273.1"	"268.9"	"284.1"	"251.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P17028"	"Zinc finger protein 24 OS=Homo sapiens OX=9606 GN=ZNF24 PE=1 SV=4"	"0.001"	""	"2"	"1"	"2"	"1"	"368"	"42.1"	"6.21"	"232.44"	"2.18"	"1"	"1"	"developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00096, Pf02023"	"7572"	"ENSG00000172466"	"ZNF24"	"hsa:7572; O14754; P17028; Q53YE4; Q6ICR5; Q8IZN4"	""	""	"0"	"0"	"138.0"	"137.1"	"142.3"	"148.9"	"135.1"	"155.2"	"175.1"	"200.3"	"206.5"	"328.8"	"407.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8ND04"	"Protein SMG8 OS=Homo sapiens OX=9606 GN=SMG8 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"991"	"109.6"	"7.68"	"263.87"	"2.18"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol"	""	"Pf10220"	"55181"	"ENSG00000167447"	"SMG8"	"hsa:55181; Q8N5U5; Q8ND04; Q8TDN0; Q9H5P5; Q9NVQ1"	""	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96RW7"	"Hemicentin-1 OS=Homo sapiens OX=9606 GN=HMCN1 PE=1 SV=2"	""	""	"0"	"1"	"1"	"1"	"5635"	"613.0"	"6.49"	""	"2.18"	""	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"extracellular matrix;plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00090, Pf07474, Pf07645, Pf07679, Pf12662, Pf13927"	"83872"	"ENSG00000143341"	"HMCN1"	"A6NGE3; hsa:83872; Q5TYR7; Q96DN3; Q96DN8; Q96RW7; Q96SC3"	""	""	"0"	"0"	"25.8"	"16.6"	"28.8"	"26.4"	"27.3"	"20.3"	"24.9"	"82.8"	"73.2"	"162.1"	"208.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"G2XKQ0"	"Small ubiquitin-related modifier 5 OS=Homo sapiens OX=9606 GN=SUMO1P1 PE=1 SV=2"	""	""	"7"	"1"	"1"	"1"	"101"	"11.5"	"5.52"	""	"2.17"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"nucleus"	"other molecular function"	"Pf11976"	""	""	"SUMO1P1"	"G2XKQ0"	""	""	"0"	"0"	"219.2"	"170.6"	"220.5"	"219.1"	"191.7"	"211.9"	"261.2"	"332.2"	"306.4"	"505.3"	"677.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O75882"	"Attractin OS=Homo sapiens OX=9606 GN=ATRN PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1429"	"158.4"	"7.31"	""	"2.17"	""	"1"	"stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi"	"other molecular function"	"Pf00059, Pf00431, Pf01344, Pf01437, Pf13964"	"8455"	"ENSG00000088812"	"ATRN"	"A8KAE5; hsa:8455; O60295; O75882; O95414; Q3MIT3; Q5TDA2; Q5TDA4; Q5VYW3; Q9NTQ3; Q9NTQ4; Q9NU01; Q9NZ57; Q9NZ58; Q9UC75; Q9UDF5"	""	""	"0"	"0"	"115.9"	"47.9"	"183.7"	"163.4"	"142.2"	"155.1"	"165.6"	"201.2"	"217.4"	"299.6"	"288.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86SQ9"	"Dehydrodolichyl diphosphate synthase complex subunit DHDDS OS=Homo sapiens OX=9606 GN=DHDDS PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"333"	"38.6"	"8.28"	"303.67"	"2.17"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf01255"	"79947"	"ENSG00000117682"	"DHDDS"	"B7Z4B9; B7ZB20; D3DPK7; D3DPK8; D3DPK9; E9KL43; hsa:79947; Q5T0A4; Q86SQ9; Q8NE90; Q9BTG5; Q9BTK3; Q9H905"	""	"Synthesis of Dolichyl-phosphate; Defective DHDDS causes RP59"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P2F8"	"Signal-induced proliferation-associated 1-like protein 2 OS=Homo sapiens OX=9606 GN=SIPA1L2 PE=1 SV=2"	"0.001"	""	"1"	"1"	"2"	"1"	"1722"	"190.3"	"6.77"	"232.21"	"2.17"	"1"	"1"	"other biological processes"	"other cell component"	"enzyme regulator activity"	"Pf00595, Pf02145, Pf11881"	"57568"	"ENSG00000116991"	"SIPA1L2"	"hsa:57568; Q2TV88; Q5VXR7; Q5VXR8; Q641Q4; Q8NA38; Q96DZ3; Q9H9F6; Q9P2F8"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y692"	"Glucocorticoid modulatory element-binding protein 1 OS=Homo sapiens OX=9606 GN=GMEB1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"573"	"62.6"	"4.83"	"253.95"	"2.17"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01342"	"10691"	"ENSG00000162419"	"GMEB1"	"B1AT48; hsa:10691; Q9NWH1; Q9UKD0; Q9Y692"	"2q37 copy number variation syndrome"	""	"1"	"0"	"15.3"	"9.0"	"15.8"	"9.5"	"8.7"	"4.7"	"10.8"	"43.1"	"38.5"	"140.7"	"265.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8IYD8"	"Fanconi anemia group M protein OS=Homo sapiens OX=9606 GN=FANCM PE=1 SV=2"	""	""	"0"	"1"	"1"	"1"	"2048"	"232.0"	"6.11"	""	"2.17"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00271, Pf02732, Pf04851, Pf16783"	"57697"	"ENSG00000187790"	"FANCM"	"B2RTQ9; hsa:57697; Q3YFH9; Q8IYD8; Q8N9X6; Q9HCH6"	"DNA repair pathways, full network; Primary ovarian insufficiency"	"Fanconi Anemia Pathway"	"3"	"0"	"37.9"	"13.7"	"42.0"	"28.3"	"29.2"	"38.9"	"42.5"	"112.5"	"145.0"	"559.1"	"807.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13613"	"Myotubularin-related protein 1 OS=Homo sapiens OX=9606 GN=MTMR1 PE=1 SV=4"	"0.000"	""	"1"	"1"	"2"	"1"	"665"	"74.6"	"7.14"	"250.06"	"2.17"	"1"	"1"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf02893, Pf06602"	"8776"	"ENSG00000063601"	"MTMR1"	"A0A024RC07; hsa:8776; Q13613; Q9UBX6; Q9UEM0; Q9UQD5"	""	"RHOF GTPase cycle; Synthesis of PIPs at the plasma membrane"	"2"	"0"	"45.9"	"39.2"	"29.1"	"31.8"	"36.4"	"50.7"	"85.3"	"189.3"	"179.9"	"180.0"	"170.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q92696"	"Geranylgeranyl transferase type-2 subunit alpha OS=Homo sapiens OX=9606 GN=RABGGTA PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"567"	"65.0"	"5.67"	""	"2.16"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf01239, Pf07711"	"5875"	"ENSG00000100949; ENSG00000285193"	"RABGGTA"	"A8K5N2; D3DS69; hsa:5875; Q92696"	""	"RAB geranylgeranylation; TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15484"	"Calpain-5 OS=Homo sapiens OX=9606 GN=CAPN5 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"640"	"73.1"	"7.64"	"248.47"	"2.16"	"1"	"1"	"protein metabolism;signal transduction"	"other cell component"	"other molecular function"	"Pf00168, Pf00648, Pf01067"	"726"	"ENSG00000149260"	"CAPN5"	"hsa:726; O00263; O15484"	"Integrin-mediated cell adhesion"	"Degradation of the extracellular matrix"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HAS0"	"Protein Njmu-R1 OS=Homo sapiens OX=9606 GN=C17orf75 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"396"	"44.6"	"5.03"	"303.35"	"2.16"	"1"	"1"	"cell organization and biogenesis;transport"	"ER/Golgi;other cell component"	""	"Pf15053"	"64149"	"ENSG00000108666"	"C17orf75"	"hsa:64149; Q7Z2H4; Q9HAS0"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NPI1"	"Bromodomain-containing protein 7 OS=Homo sapiens OX=9606 GN=BRD7 PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"651"	"74.1"	"6.39"	""	"2.16"	""	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00439, Pf12024"	"29117"	"ENSG00000166164"	"BRD7"	"hsa:29117; Q4VC09; Q8N2L9; Q96KA4; Q9BV48; Q9NPI1; Q9UH59"	""	"Regulation of TP53 Activity through Acetylation"	"1"	"0"	"60.0"	"43.6"	"55.2"	"53.0"	"61.9"	"48.2"	"56.8"	"102.4"	"113.3"	"214.8"	"368.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UJW0"	"Dynactin subunit 4 OS=Homo sapiens OX=9606 GN=DCTN4 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"460"	"52.3"	"7.34"	"286.55"	"2.16"	"1"	"1"	""	"cytosol;cytoskeleton;nucleus;other cell component"	""	"Pf05502"	"51164"	"ENSG00000132912"	"DCTN4"	"B3KWW0; D3DQH0; E5RGT5; hsa:51164; Q8TAN8; Q9UJW0"	""	"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; MHC class II antigen presentation; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic"	"4"	"0"	"9.0"	"0.0"	"7.3"	"4.8"	"9.9"	"4.2"	"10.4"	"28.8"	"32.6"	"120.2"	"244.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P48200"	"Iron-responsive element-binding protein 2 OS=Homo sapiens OX=9606 GN=IREB2 PE=1 SV=4"	"0.000"	""	"1"	"1"	"2"	"1"	"963"	"105.0"	"7.05"	"244.85"	"2.16"	"1"	"1"	"other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;mitochondrion;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00330, Pf00694"	"3658"	"ENSG00000136381"	"IREB2"	"A0A0A6YY96; A8KAC7; E1CJT9; H0YKU0; hsa:3658; P48200; Q13095; Q1HE21; Q59FQ7; Q8WVK6; Q9UF17"	"Iron metabolism in placenta; Ferroptosis"	"Iron uptake and transport"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NXL9"	"DNA helicase MCM9 OS=Homo sapiens OX=9606 GN=MCM9 PE=1 SV=4"	"0.000"	""	"2"	"2"	"2"	"1"	"1143"	"127.2"	"7.74"	"249.92"	"2.16"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf17207, Pf17855"	"254394"	"ENSG00000111877"	"MCM9"	"B4DR30; B9DI77; hsa:254394; Q2KHJ0; Q8N5S5; Q9HCV5; Q9NXL9"	"Ciliary landscape; Primary ovarian insufficiency"	""	"2"	"0"	"59.3"	"56.3"	"41.7"	"39.9"	"39.3"	"40.0"	"54.5"	"91.8"	"76.3"	"133.9"	"236.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99959"	"Plakophilin-2 OS=Homo sapiens OX=9606 GN=PKP2 PE=1 SV=2"	"0.000"	""	"2"	"2"	"2"	"1"	"881"	"97.4"	"9.33"	"270.50"	"2.16"	"1"	"1"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00514"	"5318"	"ENSG00000057294"	"PKP2"	"A0AV37; B8QFA1; B8QGS6; B8QGS7; D3DUW9; hsa:5318; Q4VC01; Q99959; Q99960"	"Arrhythmogenic right ventricular cardiomyopathy; Epithelial to mesenchymal transition in colorectal cancer"	"Formation of the cornified envelope"	"4"	"0"	"187.1"	"169.7"	"161.4"	"163.4"	"168.4"	"172.8"	"194.9"	"288.1"	"268.2"	"467.2"	"651.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P79522"	"Proline-rich protein 3 OS=Homo sapiens OX=9606 GN=PRR3 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"188"	"20.6"	"9.83"	"250.18"	"2.16"	"1"	"1"	""	""	"other molecular function"	"Pf00642"	"80742"	"ENSG00000204576; ENSG00000206491; ENSG00000223766; ENSG00000223887; ENSG00000228186; ENSG00000229202; ENSG00000233564"	"PRR3"	"A1A4H4; hsa:80742; P79522; Q5RJB5; Q5STN6"	""	""	"0"	"0"	"213.3"	"157.5"	"225.0"	"197.2"	"198.3"	"181.0"	"241.5"	"281.4"	"268.8"	"366.0"	"495.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12860"	"Contactin-1 OS=Homo sapiens OX=9606 GN=CNTN1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1018"	"113.2"	"5.90"	"266.72"	"2.16"	"1"	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00041, Pf07679, Pf13927"	"1272"	"ENSG00000018236"	"CNTN1"	"A8K0H9; A8K0Y3; hsa:1272; Q12860; Q12861; Q14030; Q7M4P0; Q8N466"	""	"Activated NOTCH1 Transmits Signal to the Nucleus; NOTCH2 Activation and Transmission of Signal to the Nucleus; Neurofascin interactions"	"4"	"0"	"3.1"	"0.0"	"3.9"	"4.0"	"0.0"	"1.9"	"5.5"	"5.8"	"8.6"	"38.5"	"81.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H444"	"Charged multivesicular body protein 4b OS=Homo sapiens OX=9606 GN=CHMP4B PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"224"	"24.9"	"4.82"	"316.91"	"2.15"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf03357"	"128866"	"ENSG00000101421"	"CHMP4B"	"E1P5N4; hsa:128866; Q53ZD6; Q9H444"	""	"Sealing of the nuclear envelope (NE) by ESCRT-III; HCMV Late Events; Budding and maturation of HIV virion; Endosomal Sorting Complex Required For Transport (ESCRT); Late endosomal microautophagy; Macroautophagy; Pyroptosis; Translation of Replicase and Assembly of the Replication Transcription Complex; Translation of Replicase and Assembly of the Replication Transcription Complex"	"9"	"0"	"61.2"	"42.4"	"65.0"	"60.3"	"57.0"	"58.2"	"69.9"	"110.0"	"112.3"	"279.4"	"392.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NUY8"	"TBC1 domain family member 23 OS=Homo sapiens OX=9606 GN=TBC1D23 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"699"	"78.3"	"5.41"	"282.06"	"2.15"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes"	"cytosol;ER/Golgi;other cell component"	""	"Pf00566, Pf00581, Pf19430"	"55773"	"ENSG00000036054"	"TBC1D23"	"B9A6M5; hsa:55773; Q8TCN8; Q8WUB7; Q96D90; Q9NUY8; Q9NV75"	""	""	"0"	"0"	"39.3"	"33.9"	"39.0"	"35.4"	"46.3"	"38.2"	"45.9"	"84.5"	"98.2"	"261.7"	"353.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14832"	"Phytanoyl-CoA dioxygenase, peroxisomal OS=Homo sapiens OX=9606 GN=PHYH PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"338"	"38.5"	"8.47"	"267.19"	"2.15"	"1"	"1"	"other metabolic processes"	"cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf05721"	"5264"	"ENSG00000107537"	"PHYH"	"A8MTS8; B1ALH5; hsa:5264; O14832"	""	"TYSND1 cleaves peroxisomal proteins; Alpha-oxidation of phytanate"	"3"	"0"	"6.2"	"4.3"	"10.0"	"5.9"	"10.6"	"9.0"	"12.8"	"44.3"	"33.9"	"49.7"	"65.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55039"	"Developmentally-regulated GTP-binding protein 2 OS=Homo sapiens OX=9606 GN=DRG2 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"364"	"40.7"	"8.88"	"236.85"	"2.15"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01926, Pf02824, Pf16897"	"1819"	"ENSG00000108591"	"DRG2"	"B2R8G5; hsa:1819; P55039; Q53Y50; Q9BWB2"	"Smith-Magenis and Potocki-Lupski syndrome copy number variation"	""	"1"	"0"	"3.2"	"2.5"	"3.4"	"4.2"	"2.7"	"4.2"	"2.1"	"12.9"	"17.9"	"43.5"	"67.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P00403"	"Cytochrome c oxidase subunit 2 OS=Homo sapiens OX=9606 GN=MT-CO2 PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"227"	"25.5"	"4.82"	""	"2.15"	""	"1"	"other metabolic processes;stress response;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00116, Pf02790"	"4513"	"ENSG00000198712"	"MT-CO2"	"hsa:4513; P00403; Q37526"	"Electron transport chain: OXPHOS system in mitochondria; Endothelin pathways; EGF/EGFR signaling pathway; Nonalcoholic fatty liver disease; Neuroinflammation; Mitochondrial complex IV assembly; CCL18 signaling pathway; 5q35 copy number variation"	"Cytoprotection by HMOX1; Respiratory electron transport; TP53 Regulates Metabolic Genes"	"11"	"0"	"2.5"	"0.0"	"3.4"	"5.8"	"3.7"	"3.5"	"6.5"	"8.6"	"11.0"	"31.2"	"44.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P032"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 OS=Homo sapiens OX=9606 GN=NDUFAF4 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"175"	"20.3"	"8.82"	"250.47"	"2.15"	"1"	"1"	"cell organization and biogenesis;stress response;other biological processes"	"other membranes;cytosol;mitochondrion"	"other molecular function"	"Pf06784"	"29078"	"ENSG00000123545"	"NDUFAF4"	"B2R4J5; hsa:29078; Q9P032"	""	"Complex I biogenesis"	"1"	"0"	"167.8"	"121.4"	"149.6"	"134.1"	"118.7"	"129.3"	"162.0"	"271.7"	"247.8"	"645.4"	"783.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86UE8"	"Serine/threonine-protein kinase tousled-like 2 OS=Homo sapiens OX=9606 GN=TLK2 PE=1 SV=2"	"0.000"	""	"3"	"2"	"3"	"2"	"772"	"87.6"	"8.41"	"773.60"	"2.15"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"11011"	"ENSG00000146872"	"TLK2"	"D3DU07; hsa:11011; Q86UE8; Q9UKI7; Q9Y4F7"	"miRNA regulation of DNA damage response; DNA damage response"	""	"2"	"0"	"25.1"	"25.9"	"23.7"	"27.2"	"25.1"	"29.0"	"29.4"	"42.9"	"37.8"	"86.4"	"106.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5EBL8"	"PDZ domain-containing protein 11 OS=Homo sapiens OX=9606 GN=PDZD11 PE=1 SV=2"	"0.000"	""	"13"	"2"	"3"	"1"	"140"	"16.1"	"7.21"	"677.46"	"2.15"	"2"	"1"	"cell-cell signaling;cell organization and biogenesis;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;other cell component"	""	"Pf00595"	"51248"	"ENSG00000120509"	"PDZD11"	"D3DVU3; hsa:51248; Q5EBL8; Q6UWE1; Q9P0Q1"	""	"Ion transport by P-type ATPases; Ion influx/efflux at host-pathogen interface; Transport of vitamins, nucleosides, and related molecules; Biotin transport and metabolism; Vitamin B5 (pantothenate) metabolism"	"5"	"0"	"60.9"	"37.3"	"64.9"	"59.6"	"52.0"	"55.6"	"71.0"	"123.6"	"142.2"	"263.4"	"386.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P01111"	"GTPase NRas OS=Homo sapiens OX=9606 GN=NRAS PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"189"	"21.2"	"5.17"	"302.89"	"2.14"	"1"	"1"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi"	"other molecular function"	"Pf00071"	"4893"	"ENSG00000213281"	"NRAS"	"hsa:4893; P01111; Q14971; Q15104; Q15282"	"Alzheimer's disease and miRNA effects; Glioblastoma signaling pathways; RalA downstream regulated genes; TNF-alpha signaling pathway; Aryl hydrocarbon receptor pathway; Bladder cancer; Extracellular vesicle-mediated signaling in recipient cells; RAC1/PAK1/p38/MMP2 pathway; G protein signaling pathways; BDNF-TrkB signaling; MAPK signaling pathway; PI3K-AKT-mTOR signaling pathway and therapeutic opportunities in prostate cancer; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Endometrial cancer; PI3K-Akt signaling pathway; MAPK cascade; Ras signaling; Non-small cell lung cancer; Breast cancer pathway; Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells; Thermogenesis; Non-genomic actions of 1,25 dihydroxyvitamin D3; Relationship between inflammation, COX-2 and EGFR; Envelope proteins and their potential roles in EDMD physiopathology; Synaptic signaling pathways associated with autism spectrum disorder; Hippo-Merlin signaling dysregulation; Hepatitis B infection; Head and neck squamous cell carcinoma; Melanoma; EGFR tyrosine kinase inhibitor resistance; Kisspeptin/kisspeptin receptor system in the ovary; CCL18 signaling pathway; Regulation of actin cytoskeleton; Alzheimer's disease; GDNF signaling; JAK-STAT signaling in the regulation of Beta-cells; ErbB signaling pathway; DNA damage response (only ATM dependent); Serotonin receptor 2 and ELK-SRF/GATA4 signaling"	"Neutrophil degranulation; FCERI mediated MAPK activation; Regulation of RAS by GAPs; Signaling by BRAF and RAF1 fusions; Signaling by SCF-KIT; Downstream signal transduction; Tie2 Signaling; DAP12 signaling; Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants; Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants; Signaling by PDGFRA extracellular domain mutants; SHC1 events in ERBB2 signaling; SHC1 events in ERBB4 signaling; GRB2 events in ERBB2 signaling; Signaling by ERBB2 KD Mutants; Signaling by ERBB2 TMD/JMD mutants; RAF activation; Ras activation upon Ca2+ influx through NMDA receptor; GRB2 events in EGFR signaling; SHC1 events in EGFR signaling; NCAM signaling for neurite out-growth; Signaling by FGFR1 in disease; p38MAPK events; SHC-mediated cascade:FGFR1; FRS-mediated FGFR1 signaling; SHC-mediated cascade:FGFR2; FRS-mediated FGFR2 signaling; Signaling by FGFR2 in disease; VEGFR2 mediated cell proliferation; Estrogen-stimulated signaling through PRKCZ; SHC-mediated cascade:FGFR3; FRS-mediated FGFR3 signaling; FRS-mediated FGFR4 signaling; SHC-mediated cascade:FGFR4; Signaling by FGFR3 in disease; FLT3 Signaling; Activated NTRK2 signals through FRS2 and FRS3; RAS processing; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Erythropoietin activates RAS; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; CD209 (DC-SIGN) signaling; Activation of RAS in B cells; Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; EGFR Transactivation by Gastrin; Constitutive Signaling by EGFRvIII; Signaling by ERBB2 ECD mutants; SOS-mediated signalling; SHC-related events triggered by IGF1R; Signaling by FGFR4 in disease; MAP2K and MAPK activation; Negative regulation of MAPK pathway; Signaling by high-kinase activity BRAF mutants; RAS signaling downstream of NF1 loss-of-function variants; Insulin receptor signalling cascade; PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases; MET activates RAS signaling; Activated NTRK2 signals through RAS; Activated NTRK3 signals through RAS; Constitutive Signaling by Overexpressed ERBB2; Signaling by FLT3 fusion proteins; Signaling by FLT3 ITD and TKD mutants; Signaling by RAS GAP mutants; Signaling by RAS GTPase mutants"	"108"	"0"	"3.6"	"7.0"	"8.7"	"5.7"	"4.6"	"8.6"	"14.0"	"30.6"	"22.7"	"30.6"	"45.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92794"	"Histone acetyltransferase KAT6A OS=Homo sapiens OX=9606 GN=KAT6A PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"2004"	"224.9"	"5.68"	"305.06"	"2.14"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00628, Pf01853, Pf17772"	"7994"	"ENSG00000083168"	"KAT6A"	"hsa:7994; Q76L81; Q92794"	"Pathways affected in adenoid cystic carcinoma"	"Regulation of TP53 Activity through Acetylation; HATs acetylate histones"	"3"	"0"	"7.7"	"4.6"	"6.5"	"8.1"	"5.6"	"4.6"	"6.4"	"13.1"	"12.8"	"22.0"	"34.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P28072"	"Proteasome subunit beta type-6 OS=Homo sapiens OX=9606 GN=PSMB6 PE=1 SV=4"	""	""	"4"	"1"	"1"	"1"	"239"	"25.3"	"4.92"	""	"2.14"	""	"1"	"protein metabolism;other metabolic processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00227"	"5694"	"ENSG00000142507"	"PSMB6"	"hsa:5694; P28072; Q96J55"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Regulation of expression of SLITs and ROBOs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"62"	"0"	"22.1"	"15.9"	"19.8"	"17.3"	"19.2"	"26.0"	"23.3"	"36.7"	"39.9"	"72.2"	"104.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P39880"	"Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3"	""	""	"1"	"1"	"1"	"1"	"1505"	"164.1"	"5.90"	""	"2.14"	""	"1"	"other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00046, Pf02376"	"1523"	"ENSG00000257923"	"CUX1"	"B3KV79; J3KQV9; P39880; Q6NYH4; Q75LE5; Q75MT2; Q75MT3; Q86UJ7; Q9UEV5"	""	"Signaling by cytosolic FGFR1 fusion mutants; Signaling by FGFR1 in disease"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9H0A0"	"RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"1025"	"115.7"	"8.27"	""	"2.13"	""	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05127, Pf08351, Pf13718, Pf13725"	"55226"	"ENSG00000135372"	"NAT10"	"B4DFD5; E7ESU4; E9PMN9; hsa:55226; Q86WK5; Q9C0F4; Q9H0A0; Q9HA61; Q9NVF2"	"Metapathway biotransformation Phase I and II"	"rRNA modification in the nucleus and cytosol"	"2"	"0"	"6.9"	"6.0"	"9.2"	"8.6"	"7.0"	"6.9"	"8.6"	"12.5"	"12.0"	"31.3"	"45.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P54198"	"Protein HIRA OS=Homo sapiens OX=9606 GN=HIRA PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1017"	"111.8"	"8.07"	"252.81"	"2.13"	"1"	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00400, Pf07569"	"7290"	"ENSG00000100084"	"HIRA"	"hsa:7290; P54198; Q05BU9; Q8IXN2"	"22q11.2 copy number variation syndrome; 16p11.2 proximal deletion syndrome"	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"	"3"	"0"	"134.1"	"120.7"	"117.8"	"109.0"	"97.2"	"109.0"	"136.1"	"243.0"	"258.9"	"612.6"	"803.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q86X29"	"Lipolysis-stimulated lipoprotein receptor OS=Homo sapiens OX=9606 GN=LSR PE=1 SV=4"	""	""	"2"	"1"	"1"	"1"	"649"	"71.4"	"7.97"	""	"2.13"	""	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;other cell component"	""	"Pf05624"	"51599"	"ENSG00000105699"	"LSR"	"A6NDW3; B4DKL4; E9PHD4; hsa:51599; O00112; O00426; Q6ZT80; Q86X29; Q8NBM0; Q9BT33; Q9UQL3"	""	"LDL clearance; VLDL clearance"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96QK1"	"Vacuolar protein sorting-associated protein 35 OS=Homo sapiens OX=9606 GN=VPS35 PE=1 SV=2"	"0.000"	""	"3"	"2"	"2"	"2"	"796"	"91.6"	"5.49"	"348.29"	"2.13"	"1"	"1"	"cell-cell signaling;cell organization and biogenesis;transport;signal transduction;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding"	"Pf03635"	"55737"	"ENSG00000069329"	"VPS35"	"hsa:55737; Q561W2; Q96QK1; Q9H016; Q9H096; Q9H4P3; Q9H8J0; Q9NRS7; Q9NVG2; Q9NX80; Q9NZK2"	""	"WNT ligand biogenesis and trafficking"	"1"	"0"	"14.1"	"8.9"	"10.5"	"14.2"	"14.7"	"12.3"	"13.0"	"19.2"	"15.5"	"32.2"	"64.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P78346"	"Ribonuclease P protein subunit p30 OS=Homo sapiens OX=9606 GN=RPP30 PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"268"	"29.3"	"8.91"	""	"2.13"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01876"	"10556"	"ENSG00000148688"	"RPP30"	"B2R799; E9PB02; hsa:10556; P78346"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; tRNA processing in the nucleus"	"2"	"0"	"12.0"	"10.4"	"13.5"	"14.6"	"15.4"	"15.9"	"18.7"	"22.0"	"23.7"	"48.6"	"63.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96GN5"	"Cell division cycle-associated 7-like protein OS=Homo sapiens OX=9606 GN=CDCA7L PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"454"	"52.2"	"5.74"	""	"2.13"	""	"1"	"other biological processes"	"cytosol;nucleus"	""	"Pf10497"	"55536"	"ENSG00000164649"	"CDCA7L"	"A4D141; A6NF50; B3KTR5; B4DUT3; C9K0Y1; hsa:55536; Q6PIL4; Q86YT0; Q8IXN5; Q96C70; Q96GN5; Q9H9A2; Q9NPV2"	"Sudden infant death syndrome (SIDS) susceptibility pathways"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BWD1"	"Acetyl-CoA acetyltransferase, cytosolic OS=Homo sapiens OX=9606 GN=ACAT2 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"397"	"41.3"	"6.92"	"284.74"	"2.13"	"1"	"1"	"other metabolic processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00108, Pf02803"	"39"	"ENSG00000120437"	"ACAT2"	"B7Z233; E1P5B1; hsa:39; Q16146; Q5TCL7; Q8TDM4; Q9BWD1"	"Mevalonate pathway; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Cholesterol metabolism; Cholesterol biosynthesis pathway in hepatocytes; Enterocyte cholesterol metabolism"	"Cholesterol biosynthesis"	"6"	"0"	"14.8"	"14.9"	"22.7"	"16.4"	"12.3"	"15.0"	"19.8"	"21.7"	"17.3"	"40.0"	"68.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WWK9"	"Cytoskeleton-associated protein 2 OS=Homo sapiens OX=9606 GN=CKAP2 PE=1 SV=1"	"0.000"	""	"2"	"2"	"2"	"2"	"683"	"76.9"	"9.41"	"258.82"	"2.13"	"1"	"1"	"cell cycle OR cell proliferation;other biological processes"	"cytoskeleton;other cell component"	""	"Pf15297"	"26586"	"ENSG00000136108"	"CKAP2"	"A2BDE0; A5YM58; B4DR35; E9PD90; hsa:26586; Q3KRA5; Q5VXB4; Q8IWV5; Q8IWV6; Q8WWK9; Q96FH9; Q9H012; Q9H0D0; Q9H988; Q9HC49; Q9NVG4"	""	""	"0"	"0"	"297.9"	"275.2"	"315.1"	"279.7"	"281.8"	"265.3"	"344.8"	"553.7"	"507.1"	"933.0"	"1015.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L590"	"Protein MCM10 homolog OS=Homo sapiens OX=9606 GN=MCM10 PE=1 SV=2"	"0.000"	""	"2"	"2"	"3"	"2"	"875"	"98.1"	"8.75"	"476.63"	"2.13"	"2"	"1"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf09329, Pf09332"	"55388"	"ENSG00000065328"	"MCM10"	"A8K9I6; B7ZKZ8; hsa:55388; Q3MIR3; Q7L590; Q7LD55; Q96GX4; Q96NB6; Q9H0D7; Q9H3P9; Q9P177"	"Ciliary landscape; DNA replication"	"Activation of ATR in response to replication stress; Activation of the pre-replicative complex"	"4"	"0"	"82.3"	"73.1"	"76.5"	"80.8"	"64.9"	"68.8"	"98.0"	"96.8"	"92.2"	"135.3"	"179.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13905"	"Rap guanine nucleotide exchange factor 1 OS=Homo sapiens OX=9606 GN=RAPGEF1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1077"	"120.5"	"5.92"	"285.09"	"2.13"	"1"	"1"	"developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00617, Pf00618"	"2889"	"ENSG00000107263"	"RAPGEF1"	"hsa:2889; Q13905; Q5JUE4; Q68DL3; Q8IV73"	"Integrin-mediated cell adhesion; Androgen receptor network in prostate cancer; B cell receptor signaling pathway; IL-3 signaling pathway; Focal adhesion; Hepatocyte growth factor receptor signaling; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Insulin signaling; Interferon type I signaling pathways"	"RAC3 GTPase cycle; Regulation of signaling by CBL; Downstream signal transduction; Erythropoietin activates RAS; Frs2-mediated activation; MET activates RAP1 and RAC1"	"16"	"0"	"5.6"	"0.0"	"5.0"	"6.9"	"8.3"	"4.4"	"6.2"	"44.8"	"40.6"	"131.8"	"168.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q149N8"	"E3 ubiquitin-protein ligase SHPRH OS=Homo sapiens OX=9606 GN=SHPRH PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1683"	"193.0"	"7.47"	""	"2.13"	""	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf00538"	"257218"	"ENSG00000146414"	"SHPRH"	"hsa:257218; Q149N8; Q149N9; Q5VV79; Q68DS5; Q7Z5J5; Q8IVE8; Q8IWQ9; Q8N1S8; Q8NBR7"	""	"E3 ubiquitin ligases ubiquitinate target proteins"	"1"	"0"	"71.6"	"38.1"	"98.9"	"124.8"	"65.4"	"79.7"	"102.7"	"86.9"	"204.9"	"257.9"	"141.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q6PGP7"	"Tetratricopeptide repeat protein 37 OS=Homo sapiens OX=9606 GN=TTC37 PE=1 SV=1"	""	""	"1"	"1"	"1"	"1"	"1564"	"175.4"	"7.53"	""	"2.13"	""	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf13181, Pf13432"	"9652"	"ENSG00000198677"	"SKIC3"	"hsa:9652; O15077; Q6PGP7; Q6PJI3"	""	"mRNA decay by 3' to 5' exoribonuclease"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8TDI7"	"Transmembrane channel-like protein 2 OS=Homo sapiens OX=9606 GN=TMC2 PE=2 SV=3"	""	""	"2"	"1"	"2"	"1"	"906"	"102.5"	"9.47"	""	"2.13"	""	"1"	"transport;other biological processes"	"plasma membrane;other membranes;other cell component"	"transporter activity"	"Pf07810"	"117532"	"ENSG00000149488"	"TMC2"	"hsa:117532; Q5JXT0; Q5JXT1; Q6UWW4; Q6ZS41; Q8N9F3; Q8TDI7; Q9BYN2; Q9BYN3; Q9BYN4; Q9BYN5"	""	"Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea"	"2"	"0"	"38.7"	"11.4"	"57.3"	"48.4"	"43.7"	"41.4"	"50.0"	"79.4"	"89.6"	"150.7"	"195.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86WA6"	"Valacyclovir hydrolase OS=Homo sapiens OX=9606 GN=BPHL PE=1 SV=1"	"0.000"	""	"6"	"2"	"2"	"2"	"291"	"32.5"	"9.14"	"364.75"	"2.12"	"1"	"1"	"other metabolic processes;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf00561"	"670"	"ENSG00000137274"	"BPHL"	"hsa:670; Q00306; Q13855; Q3KP51; Q86WA6"	""	"Phase I - Functionalization of compounds"	"1"	"0"	"27.6"	"16.3"	"53.5"	"40.2"	"46.4"	"44.0"	"53.9"	"92.0"	"98.5"	"268.3"	"303.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96NL6"	"Sodium channel and clathrin linker 1 OS=Homo sapiens OX=9606 GN=SCLT1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"688"	"80.9"	"6.07"	"255.30"	"2.12"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes"	"other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	""	"132320"	"ENSG00000151466"	"SCLT1"	"A4QN04; hsa:132320; Q0VAH2; Q6P2M4; Q96NL6"	"Genes related to primary cilium development (based on CRISPR); Ciliopathies; Bardet-Biedl syndrome"	"Anchoring of the basal body to the plasma membrane"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P0DPB5"	"Protein POLR1D, isoform 2 OS=Homo sapiens OX=9606 GN=POLR1D PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"122"	"14.3"	"9.88"	"308.81"	"2.12"	"1"	"1"	""	"cytosol;nucleus"	""	""	"51082"	"ENSG00000186184"	"POLR1D"	"P0DPB5; Q5TBX2; Q96BR3; Q9Y2S0"	"Pyrimidine metabolism; Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"16"	"0"	"150.7"	"152.5"	"140.6"	"130.9"	"152.6"	"125.7"	"178.7"	"194.7"	"185.3"	"246.3"	"337.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96QE3"	"ATPase family AAA domain-containing protein 5 OS=Homo sapiens OX=9606 GN=ATAD5 PE=1 SV=4"	"0.000"	""	"1"	"1"	"2"	"1"	"1844"	"207.4"	"9.19"	"253.20"	"2.12"	"1"	"1"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00004"	"79915"	"ENSG00000176208"	"ATAD5"	"hsa:79915; Q05DH0; Q69YR6; Q96QE3; Q9H9I1"	""	""	"0"	"0"	"9.4"	"8.6"	"11.8"	"10.9"	"14.5"	"10.8"	"13.0"	"18.1"	"19.8"	"38.2"	"29.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q2KHT3"	"Protein CLEC16A OS=Homo sapiens OX=9606 GN=CLEC16A PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1053"	"117.6"	"5.86"	""	"2.12"	""	"1"	"other metabolic processes;stress response;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf09758, Pf19439"	"23274"	"ENSG00000038532"	"CLEC16A"	"hsa:23274; O15058; Q2KHT3; Q6ZTB2"	"Vitamin D receptor pathway"	""	"1"	"0"	"52.0"	"32.2"	"58.9"	"61.2"	"53.7"	"49.0"	"64.2"	"93.9"	"87.8"	"214.8"	"384.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75694"	"Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1"	"0.000"	""	"2"	"3"	"4"	"3"	"1391"	"155.1"	"6.16"	"714.93"	"2.11"	"3"	"1"	"cell-cell signaling;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;nucleus"	"other molecular function"	"Pf03177, Pf08801"	"9631"	"ENSG00000113569"	"NUP155"	"hsa:9631; O75694; Q9UBE9; Q9UFL5"	""	"HCMV Late Events; HCMV Early Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Postmitotic nuclear pore complex (NPC) reformation"	"29"	"0"	"434.9"	"324.8"	"405.1"	"415.9"	"390.9"	"350.6"	"500.2"	"622.2"	"551.3"	"942.6"	"1168.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q86T65"	"Disheveled-associated activator of morphogenesis 2 OS=Homo sapiens OX=9606 GN=DAAM2 PE=1 SV=3"	""	""	"1"	"1"	"1"	"1"	"1068"	"123.4"	"6.80"	""	"2.11"	""	"1"	"cell-cell signaling;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	""	"cytoskeletal activity;other molecular function"	"Pf02181, Pf06367, Pf06371"	"23500"	"ENSG00000146122"	"DAAM2"	"G5EA45; hsa:23500; Q5T4T8; Q5T4U0; Q86T65; Q9NQI5; Q9Y4G0"	"Wnt signaling"	""	"1"	"0"	"16.7"	"9.6"	"20.1"	"17.1"	"12.6"	"18.4"	"29.4"	"65.9"	"63.2"	"116.6"	"120.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q12934"	"Filensin OS=Homo sapiens OX=9606 GN=BFSP1 PE=1 SV=3"	""	""	"2"	"1"	"2"	"1"	"665"	"74.5"	"5.14"	""	"2.11"	""	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00038"	"631"	"ENSG00000125864"	"BFSP1"	"F5H0G1; hsa:631; O43595; O76034; O95676; Q12934; Q8IVZ6; Q9HBX4"	""	""	"0"	"0"	"118.5"	"89.6"	"120.6"	"120.2"	"104.8"	"116.9"	"132.8"	"214.7"	"217.4"	"409.0"	"498.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"A8TX70"	"Collagen alpha-5(VI) chain OS=Homo sapiens OX=9606 GN=COL6A5 PE=1 SV=1"	""	""	"1"	"1"	"1"	"1"	"2615"	"289.7"	"6.95"	""	"2.11"	""	"1"	"cell adhesion"	"non-structural extracellular;other cell component"	""	"Pf00092, Pf01391"	"256076"	"ENSG00000172752"	"COL6A5"	"A8TX70; A9J6L2; A9J6L4; A9J6L6; A9J6L7; A9J6M0; A9J6M1; A9J6M2; B5MEA7; hsa:256076; Q6ZW26; Q8NA36"	"PI3K-Akt signaling pathway"	"Collagen degradation; Signaling by PDGF; Assembly of collagen fibrils and other multimeric structures; Integrin cell surface interactions; ECM proteoglycans; NCAM1 interactions; Collagen chain trimerization"	"9"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y221"	"60S ribosome subunit biogenesis protein NIP7 homolog OS=Homo sapiens OX=9606 GN=NIP7 PE=1 SV=1"	""	""	"6"	"1"	"1"	"1"	"180"	"20.4"	"8.51"	""	"2.11"	""	"1"	"cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf03657, Pf17833"	"51388"	"ENSG00000132603"	"NIP7"	"B2RD04; hsa:51388; Q9NZZ0; Q9Y221"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P42858"	"Huntingtin OS=Homo sapiens OX=9606 GN=HTT PE=1 SV=2"	""	""	"0"	"1"	"1"	"1"	"3142"	"347.4"	"6.20"	""	"2.11"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf12372"	"3064"	"ENSG00000197386"	"HTT"	"hsa:3064; P42858; Q9UQB7"	"Mesodermal commitment pathway; Mesodermal commitment pathway; ERK pathway in Huntington's disease; Rett syndrome causing genes; 15q25 copy number variation"	"Regulation of MECP2 expression and activity"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P021"	"Cysteine-rich PDZ-binding protein OS=Homo sapiens OX=9606 GN=CRIPT PE=1 SV=1"	"0.000"	""	"12"	"1"	"2"	"1"	"101"	"11.2"	"9.47"	"1061.49"	""	"1"	""	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf10235"	"9419"	"ENSG00000119878"	"CRIPT"	"hsa:9419; Q9P021"	""	""	"0"	"0"	"117.2"	"98.4"	"114.5"	"115.1"	"113.0"	"103.9"	"141.1"	"166.1"	"174.3"	"254.8"	"298.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23258"	"Tubulin gamma-1 chain OS=Homo sapiens OX=9606 GN=TUBG1 PE=1 SV=2"	"0.000"	""	"6"	"2"	"2"	"2"	"451"	"51.1"	"6.14"	"839.92"	""	"2"	""	"cell cycle OR cell proliferation;cell organization and biogenesis"	"cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00091, Pf03953"	"7283"	"ENSG00000131462"	"TUBG1"	"hsa:7283; P23258; Q53X79; Q9BW59"	"Alstrom syndrome"	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"8"	"0"	"92.5"	"78.0"	"82.2"	"83.5"	"75.6"	"101.7"	"135.9"	"239.8"	"303.3"	"410.3"	"277.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UQ84"	"Exonuclease 1 OS=Homo sapiens OX=9606 GN=EXO1 PE=1 SV=2"	"0.000"	""	"3"	"2"	"2"	"2"	"846"	"94.0"	"8.31"	"797.94"	""	"2"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00752, Pf00867"	"9156"	"ENSG00000174371"	"EXO1"	"hsa:9156; O60545; O75214; O75466; Q5T396; Q96IJ1; Q9UG38; Q9UNW0; Q9UQ84"	"DNA repair pathways, full network; DNA mismatch repair; Primary ovarian insufficiency"	"Regulation of TP53 Activity through Phosphorylation; Resolution of D-loop Structures through Holliday Junction Intermediates; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"19"	"0"	"30.6"	"26.3"	"28.4"	"29.7"	"25.0"	"29.0"	"36.5"	"41.9"	"39.1"	"56.9"	"56.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62072"	"Mitochondrial import inner membrane translocase subunit Tim10 OS=Homo sapiens OX=9606 GN=TIMM10 PE=1 SV=1"	"0.000"	""	"16"	"1"	"1"	"1"	"90"	"10.3"	"6.29"	"704.93"	""	"1"	""	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf02953"	"26519"	"ENSG00000134809"	"TIMM10"	"A8K136; hsa:26519; P62072; Q9WV99; Q9WVA0; Q9Y5J8"	""	"Mitochondrial protein import"	"1"	"0"	"183.6"	"151.4"	"198.2"	"177.6"	"161.5"	"169.9"	"189.2"	"254.8"	"239.0"	"699.8"	"1812.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25490"	"Transcriptional repressor protein YY1 OS=Homo sapiens OX=9606 GN=YY1 PE=1 SV=2"	"0.000"	""	"6"	"2"	"2"	"2"	"414"	"44.7"	"6.25"	"686.34"	""	"2"	""	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00096"	"7528"	"ENSG00000100811"	"YY1"	"hsa:7528; P25490; Q14935"	"Sterol regulatory element-binding proteins (SREBP) signaling; Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4); Pleural mesothelioma"	"Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; UCH proteinases; DNA Damage Recognition in GG-NER; TFAP2 (AP-2) family regulates transcription of growth factors and their receptors"	"8"	"0"	"447.2"	"281.1"	"383.6"	"403.7"	"349.9"	"356.4"	"474.8"	"465.3"	"452.3"	"526.6"	"739.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IZL8"	"Proline-, glutamic acid- and leucine-rich protein 1 OS=Homo sapiens OX=9606 GN=PELP1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"1130"	"119.6"	"4.34"	"676.14"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf08166, Pf08167"	"27043"	"ENSG00000141456"	"PELP1"	"hsa:27043; O15450; Q5EGN3; Q6NTE6; Q8IZL8; Q96FT1; Q9BU60"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; PTK6 Expression"	"2"	"0"	"62.1"	"49.7"	"63.4"	"64.7"	"54.4"	"37.8"	"71.6"	"114.2"	"145.4"	"291.1"	"419.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55199"	"RNA polymerase II elongation factor ELL OS=Homo sapiens OX=9606 GN=ELL PE=1 SV=1"	"0.000"	""	"3"	"2"	"2"	"2"	"621"	"68.2"	"9.33"	"665.10"	""	"2"	""	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf07303, Pf10390"	"8178"	"ENSG00000105656"	"ELL"	"hsa:8178; P55199"	"Interactome of polycomb repressive complex 2 (PRC2)"	"Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; Transcription-Coupled Nucleotide Excision Repair (TC-NER)"	"14"	"0"	"60.0"	"47.5"	"45.5"	"49.8"	"46.9"	"56.6"	"66.5"	"82.9"	"81.4"	"160.5"	"250.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"B7ZAP0"	"Rab GTPase-activating protein 1-like, isoform 10 OS=Homo sapiens OX=9606 GN=RABGAP1L PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"253"	"29.0"	"5.33"	"661.80"	""	"1"	""	""	""	""	""	"9910"	"ENSG00000152061"	"RABGAP1L"	"B7ZAA4; B7ZAP0; hsa:9910"	""	""	"0"	"0"	"583.3"	"436.6"	"526.3"	"536.2"	"444.6"	"460.1"	"646.8"	"1023.0"	"951.1"	"1713.2"	"2104.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H6R0"	"ATP-dependent RNA helicase DHX33 OS=Homo sapiens OX=9606 GN=DHX33 PE=1 SV=2"	"0.000"	""	"2"	"1"	"1"	"1"	"707"	"78.8"	"8.91"	"650.90"	""	"1"	""	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"56919"	"ENSG00000005100"	"DHX33"	"B4DHF9; hsa:56919; Q4G149; Q5CZ73; Q9H5M9; Q9H6R0"	""	""	"0"	"0"	"29.5"	"27.0"	"21.6"	"22.1"	"24.9"	"23.4"	"31.7"	"43.3"	"42.3"	"70.7"	"104.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N1I0"	"Dedicator of cytokinesis protein 4 OS=Homo sapiens OX=9606 GN=DOCK4 PE=1 SV=3"	"0.000"	""	"1"	"1"	"1"	"1"	"1966"	"225.1"	"7.65"	"642.33"	""	"1"	""	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf06920, Pf07653, Pf14429, Pf16172, Pf20421, Pf20422"	"9732"	"ENSG00000128512"	"DOCK4"	"hsa:9732; O14584; O94824; Q8N1I0; Q8NB45"	""	"RAC1 GTPase cycle; RAC2 GTPase cycle; RHOG GTPase cycle; Factors involved in megakaryocyte development and platelet production"	"4"	"0"	"6.8"	"4.9"	"4.6"	"7.6"	"17.8"	"36.8"	"44.9"	"39.8"	"30.9"	"29.1"	"27.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99627"	"COP9 signalosome complex subunit 8 OS=Homo sapiens OX=9606 GN=COPS8 PE=1 SV=1"	"0.000"	""	"6"	"1"	"1"	"1"	"209"	"23.2"	"5.38"	"638.31"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf10075"	"10920"	"ENSG00000198612"	"COPS8"	"A8K1H6; hsa:10920; Q53QS9; Q99627"	"Ciliary landscape; 2q37 copy number variation syndrome"	"DNA Damage Recognition in GG-NER; Cargo recognition for clathrin-mediated endocytosis; Neddylation; Formation of TC-NER Pre-Incision Complex"	"6"	"0"	"12.8"	"11.2"	"14.5"	"14.6"	"15.4"	"23.9"	"46.3"	"139.0"	"149.8"	"469.5"	"930.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49023"	"Paxillin OS=Homo sapiens OX=9606 GN=PXN PE=1 SV=3"	"0.000"	""	"2"	"1"	"1"	"1"	"591"	"64.5"	"6.19"	"637.47"	""	"1"	""	"cell adhesion;cell organization and biogenesis;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00412, Pf03535"	"5829"	"ENSG00000089159"	"PXN"	"B2RAI3; B7ZMB4; hsa:5829; O14970; O14971; O60360; P49023; Q5HYA4"	"Integrin-mediated cell adhesion; Prolactin signaling pathway; Androgen receptor network in prostate cancer; Oncostatin M signaling pathway; Focal adhesion; Hepatocyte growth factor receptor signaling; RAC1/PAK1/p38/MMP2 pathway; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Gastrin signaling pathway; 3q29 copy number variation syndrome; Regulation of actin cytoskeleton; GDNF signaling"	"VEGFA-VEGFR2 Pathway; GAB1 signalosome; Smooth Muscle Contraction; PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases; Localization of the PINCH-ILK-PARVIN complex to focal adhesions; Regulation of cytoskeletal remodeling and cell spreading by IPP complex components"	"20"	"0"	"78.5"	"56.9"	"77.6"	"73.6"	"68.7"	"45.6"	"85.5"	"117.4"	"126.5"	"177.9"	"264.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IVW6"	"AT-rich interactive domain-containing protein 3B OS=Homo sapiens OX=9606 GN=ARID3B PE=1 SV=2"	"0.000"	""	"3"	"1"	"1"	"1"	"561"	"60.6"	"7.52"	"591.34"	""	"1"	""	"other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf01388"	"10620"	"ENSG00000179361"	"ARID3B"	"hsa:10620; O95443; Q59HC9; Q6P9C9; Q8IVW6"	""	""	"0"	"0"	"24.8"	"21.5"	"21.8"	"26.5"	"21.2"	"21.4"	"26.2"	"30.6"	"25.1"	"34.3"	"56.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P02768"	"Serum albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2"	"0.000"	""	"2"	"1"	"1"	"1"	"609"	"69.3"	"6.28"	"589.70"	""	"1"	""	"stress response;other biological processes"	"non-structural extracellular;ER/Golgi;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00273"	"213"	"ENSG00000163631"	"ALB"	"E7ESS9; hsa:213; O95574; P02768; P04277; Q13140; Q645G4; Q68DN5; Q6UXK4; Q86YG0; Q8IUK7; Q9P157; Q9P1I7; Q9UHS3; Q9UJZ0"	"Selenium micronutrient network; Vitamin B12 metabolism; Folate metabolism; Complement system; VEGFA-VEGFR2 signaling"	"Scavenging of heme from plasma; Platelet degranulation ; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Cytoprotection by HMOX1; Aspirin ADME; Ciprofloxacin ADME; Recycling of bile acids and salts; Prednisone ADME; Heme degradation; HDL remodeling; Heme biosynthesis"	"17"	"0"	"29.7"	"14.2"	"20.5"	"20.1"	"11.7"	"16.0"	"26.6"	"43.1"	"55.9"	"68.0"	"117.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P27824"	"Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2"	"0.000"	""	"3"	"1"	"1"	"1"	"592"	"67.5"	"4.60"	"577.30"	""	"1"	""	"protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;translational apparatus;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00262"	"821"	"ENSG00000127022; ENSG00000283777"	"CANX"	"B2R5V8; B4DGP8; B4E2T8; D3DWQ3; D6R9K3; hsa:821; P27824"	"15q11q13 copy number variation"	"Maturation of spike protein; MHC class II antigen presentation; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Interleukin-35 Signalling; Interleukin-27 signaling; Assembly of Viral Components at the Budding Site; Calnexin/calreticulin cycle; Maturation of spike protein"	"9"	"0"	"42.2"	"27.5"	"48.4"	"52.3"	"27.3"	"25.6"	"44.5"	"55.1"	"86.9"	"171.0"	"330.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P15336"	"Cyclic AMP-dependent transcription factor ATF-2 OS=Homo sapiens OX=9606 GN=ATF2 PE=1 SV=4"	"0.000"	""	"3"	"1"	"1"	"1"	"505"	"54.5"	"7.88"	"569.37"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00170"	"1386"	"ENSG00000115966"	"ATF2"	"A1L3Z2; A4D7U4; A4D7U5; A4D7V1; D3DPE9; G8JLM5; hsa:1386; P15336; Q13000; Q3B7B7; Q4ZFU9; Q53RY2; Q8TAR1; Q96JT8"	"Energy metabolism; IL-1 signaling pathway; B cell receptor signaling pathway; AGE/RAGE pathway; ATM signaling pathway; Interleukin-1 (IL-1) structural pathway; Myometrial relaxation and contraction pathways; MAPK signaling pathway; ATM signaling in development and disease ; VEGFA-VEGFR2 signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; IL-4 signaling pathway; DNA IR-double strand breaks and cellular response via ATM; Ethanol effects on histone modifications; p38 MAPK signaling pathway; PI3K-Akt signaling pathway; Thermogenesis; Gastrin signaling pathway; Hepatitis B infection; Thyroid hormones production and peripheral downstream signaling effects; Host-pathogen interaction of human coronaviruses - MAPK signaling; Pleural mesothelioma; 10q11.21q11.23 copy number variation syndrome; T-cell receptor signaling pathway"	"NGF-stimulated transcription; Heme signaling; Regulation of PTEN gene transcription; TP53 Regulates Transcription of DNA Repair Genes; Circadian Clock; Transcriptional activation of mitochondrial biogenesis; Estrogen-dependent gene expression; HATs acetylate histones; Activation of the AP-1 family of transcription factors; Response of EIF2AK4 (GCN2) to amino acid deficiency"	"34"	"0"	"30.9"	"26.1"	"26.8"	"20.2"	"18.7"	"19.5"	"25.2"	"25.9"	"28.3"	"64.9"	"77.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95926"	"Pre-mRNA-splicing factor SYF2 OS=Homo sapiens OX=9606 GN=SYF2 PE=1 SV=1"	"0.000"	""	"7"	"1"	"1"	"1"	"243"	"28.7"	"8.40"	"563.86"	""	"1"	""	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	""	"Pf08231"	"25949"	"ENSG00000117614"	"SYF2"	"hsa:25949; O95926; Q5TH73"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"11.8"	"14.0"	"7.9"	"6.7"	"9.6"	"8.2"	"10.1"	"9.1"	"8.1"	"13.7"	"28.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63000"	"Ras-related C3 botulinum toxin substrate 1 OS=Homo sapiens OX=9606 GN=RAC1 PE=1 SV=1"	"0.000"	""	"8"	"1"	"1"	"1"	"192"	"21.4"	"8.50"	"562.48"	""	"1"	""	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00071"	"5879"	"ENSG00000136238"	"RAC1"	"hsa:5879; O95501; P15154; P63000; Q3Y4D3; Q5JAA8; Q9BTB4"	"Androgen receptor signaling pathway; Nucleotide-binding oligomerization domain (NOD) pathway; Target of rapamycin signaling; Physiological and pathological hypertrophy of the heart; MicroRNAs in cardiomyocyte hypertrophy; Integrin-mediated cell adhesion; RANKL/RANK signaling pathway; Leptin signaling pathway; TNF-related weak inducer of apoptosis (TWEAK) signaling pathway; Prolactin signaling pathway; Microtubule cytoskeleton regulation; RalA downstream regulated genes; B cell receptor signaling pathway; TNF-alpha signaling pathway; AGE/RAGE pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Spinal cord injury; Alpha 6 beta 4 signaling pathway; Amyotrophic lateral sclerosis (ALS); Cardiac hypertrophic response; Focal adhesion; RAC1/PAK1/p38/MMP2 pathway; Wnt signaling pathway; IL6 signaling pathway; Hepatitis C and hepatocellular carcinoma; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Microglia pathogen phagocytosis pathway; Robo4 and VEGF signaling pathways crosstalk; p38 MAPK signaling pathway; PI3K-Akt signaling pathway; Chromosomal and microsatellite instability in colorectal cancer ; Ebola virus infection in host; Ras signaling; Pancreatic adenocarcinoma pathway; Wnt signaling; Ciliary landscape; EGF/EGFR signaling pathway; Nonalcoholic fatty liver disease; Hippo signaling regulation pathways; Leukocyte-intrinsic Hippo pathway functions; Neural crest cell migration during development; Neural crest cell migration in cancer; Gastrin signaling pathway; Melanoma; Netrin-UNC5B signaling pathway; Insulin signaling; CAMKK2 pathway; Opioid receptor pathways; Regulation of actin cytoskeleton; GDNF signaling; 2q13 copy number variation syndrome; 2q21.1 copy number variation syndrome; 2q37 copy number variation syndrome; G13 signaling pathway; Genetic causes of porto-sinusoidal vascular disease; TROP2 regulatory signaling; 13q12.12 copy number variation; Interferon type I signaling pathways; DNA damage response (only ATM dependent); Toll-like receptor signaling pathway"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; EPHB-mediated forward signaling; RAC1 GTPase cycle; NRAGE signals death through JNK; DCC mediated attractive signaling; Neutrophil degranulation; MAPK6/MAPK4 signaling; Factors involved in megakaryocyte development and platelet production; FCERI mediated MAPK activation; Translocation of SLC2A4 (GLUT4) to the plasma membrane; RHO GTPases activate IQGAPs; RHO GTPases Activate Formins; PIP3 activates AKT signaling; Constitutive Signaling by Aberrant PI3K in Cancer; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; GPVI-mediated activation cascade; Signaling by SCF-KIT; DAP12 signaling; Ephrin signaling; RHO GTPases activate CIT; PCP/CE pathway; WNT5:FZD7-mediated leishmania damping; EPH-ephrin mediated repulsion of cells; Sema3A PAK dependent Axon repulsion; SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion; Signal transduction by L1; RHO GTPases activate PKNs; RHO GTPases activate PAKs; DSCAM interactions; Azathioprine ADME; VEGFR2 mediated vascular permeability; Sema4D mediated inhibition of cell attachment and migration; Inactivation of CDC42 and RAC1; Activation of RAC1; CD28 dependent Vav1 pathway; PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases; Nef and signal transduction; RHO GTPases Activate NADPH Oxidases; NTRK2 activates RAC1; MET activates RAP1 and RAC1; Activation of RAC1 downstream of NMDARs; Activated NTRK2 signals through CDK5; RHO GTPases activate KTN1"	"108"	"0"	"79.2"	"67.3"	"84.7"	"71.0"	"60.6"	"71.7"	"103.8"	"196.6"	"194.6"	"443.6"	"719.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TDX7"	"Serine/threonine-protein kinase Nek7 OS=Homo sapiens OX=9606 GN=NEK7 PE=1 SV=1"	"0.000"	""	"4"	"1"	"1"	"1"	"302"	"34.5"	"8.25"	"552.22"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"140609"	"ENSG00000151414"	"NEK7"	"A6NGT8; hsa:140609; Q8TDX7"	"Ciliary landscape"	"EML4 and NUDC in mitotic spindle formation; Nuclear Pore Complex (NPC) Disassembly; Activation of NIMA Kinases NEK9, NEK6, NEK7"	"4"	"0"	"33.1"	"20.2"	"38.0"	"33.4"	"33.6"	"35.2"	"41.1"	"151.2"	"141.8"	"370.6"	"464.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50454"	"Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2"	"0.000"	""	"3"	"1"	"1"	"1"	"418"	"46.4"	"8.69"	"539.47"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"non-structural extracellular;other membranes;ER/Golgi"	"enzyme regulator activity;other molecular function"	"Pf00079"	"871"	"ENSG00000149257"	"SERPINH1"	"B3KVJ3; hsa:871; P29043; P50454; Q5XPB4; Q6NSJ6; Q8IY96; Q9NP88"	"Endochondral ossification; Type I collagen synthesis in the context of osteogenesis imperfecta; Endochondral ossification with skeletal dysplasias; 15q13.3 copy number variation syndrome; 15q11q13 copy number variation"	"Collagen biosynthesis and modifying enzymes"	"6"	"0"	"33.0"	"35.5"	"31.8"	"36.4"	"34.7"	"41.5"	"46.2"	"60.3"	"58.3"	"90.6"	"134.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99996"	"A-kinase anchor protein 9 OS=Homo sapiens OX=9606 GN=AKAP9 PE=1 SV=4"	"0.000"	""	"0"	"2"	"2"	"1"	"3907"	"452.7"	"4.98"	"535.23"	""	"2"	""	"cell-cell signaling;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf10495"	"10142"	"ENSG00000127914"	"AKAP9"	"A4D1F0; A4D1F2; A4D1F4; hsa:10142; O14869; O43355; O94895; Q75N20; Q99996; Q9UQH3; Q9UQQ4; Q9Y6B8; Q9Y6Y2"	"G protein signaling pathways; NO/cGMP/PKG mediated neuroprotection"	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Signaling by BRAF and RAF1 fusions; Phase 3 - rapid repolarisation; Phase 2 - plateau phase"	"12"	"0"	"49.5"	"38.0"	"30.8"	"41.2"	"32.4"	"35.8"	"42.4"	"92.5"	"87.1"	"197.9"	"293.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05783"	"Keratin, type I cytoskeletal 18 OS=Homo sapiens OX=9606 GN=KRT18 PE=1 SV=2"	"0.000"	""	"4"	"2"	"2"	"1"	"430"	"48.0"	"5.45"	"535.22"	""	"2"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00038"	"3875"	"ENSG00000111057"	"KRT18"	"hsa:3875; P05783; Q53G38; Q5U0N8; Q9BW26"	"Pathogenic Escherichia coli infection"	"Formation of the cornified envelope"	"3"	"0"	"15.9"	"11.4"	"13.4"	"13.7"	"10.3"	"9.2"	"21.5"	"39.4"	"41.0"	"139.8"	"259.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96BX8"	"MOB kinase activator 3A OS=Homo sapiens OX=9606 GN=MOB3A PE=1 SV=1"	"0.000"	""	"6"	"1"	"1"	"1"	"217"	"25.4"	"8.63"	"532.72"	""	"1"	""	"signal transduction;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf03637"	"126308"	"ENSG00000172081"	"MOB3A"	"B3KTF1; hsa:126308; O75249; Q8TF69; Q96BX8"	""	""	"0"	"0"	"0.0"	"2.1"	"0.0"	"0.0"	"2.8"	"5.0"	"6.2"	"17.5"	"43.6"	"67.2"	"121.9"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6I4"	"Ubiquitin carboxyl-terminal hydrolase 3 OS=Homo sapiens OX=9606 GN=USP3 PE=1 SV=2"	"0.000"	""	"3"	"1"	"1"	"1"	"520"	"58.9"	"8.18"	"528.90"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf00443, Pf02148"	"9960"	"ENSG00000140455"	"USP3"	"B4DVU5; F5H1A6; hsa:9960; Q8WVD0; Q9Y6I4"	""	"Ub-specific processing proteases"	"1"	"0"	"50.9"	"46.4"	"51.0"	"61.7"	"51.9"	"40.5"	"60.9"	"93.7"	"79.0"	"86.1"	"94.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKK9"	"ADP-sugar pyrophosphatase OS=Homo sapiens OX=9606 GN=NUDT5 PE=1 SV=1"	"0.000"	""	"7"	"1"	"1"	"1"	"219"	"24.3"	"4.94"	"528.08"	""	"1"	""	"cell organization and biogenesis;other metabolic processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00293"	"11164"	"ENSG00000165609"	"NUDT5"	"A8K516; hsa:11164; Q6IAG0; Q9UH49; Q9UKK9"	""	"Phosphate bond hydrolysis by NUDT proteins"	"1"	"0"	"10.4"	"7.7"	"7.8"	"6.6"	"9.4"	"11.1"	"8.6"	"8.7"	"15.6"	"20.7"	"28.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H4G0"	"Band 4.1-like protein 1 OS=Homo sapiens OX=9606 GN=EPB41L1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"881"	"98.4"	"5.62"	"524.17"	""	"1"	""	"cell organization and biogenesis"	"plasma membrane;other membranes;cytosol;cytoskeleton"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf04382, Pf05902, Pf08736, Pf09379, Pf09380"	"2036"	"ENSG00000088367"	"EPB41L1"	"hsa:2036; O15046; Q4VXM6; Q4VXM7; Q4VXM8; Q4VXN4; Q6ZT61; Q8IUU7; Q96CV5; Q96L65; Q9H4G0"	"Splicing factor NOVA regulated synaptic proteins"	"Trafficking of AMPA receptors; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Neurexins and neuroligins"	"5"	"0"	"23.1"	"20.4"	"23.8"	"19.4"	"24.7"	"25.9"	"31.4"	"171.5"	"182.7"	"258.8"	"248.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P56181"	"NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV3 PE=1 SV=2"	"0.000"	""	"15"	"1"	"1"	"1"	"108"	"11.9"	"9.70"	"509.58"	""	"1"	""	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf15880"	"4731"	"ENSG00000160194"	"NDUFV3"	"A8K0M1; hsa:4731; J3KNX7; P56181; Q6FGD3; Q8WU60; Q9HCR5"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"50.5"	"39.2"	"34.4"	"44.8"	"36.5"	"46.1"	"50.6"	"102.3"	"98.5"	"190.8"	"270.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15631"	"Translin OS=Homo sapiens OX=9606 GN=TSN PE=1 SV=1"	"0.000"	""	"5"	"1"	"1"	"1"	"228"	"26.2"	"6.44"	"508.27"	""	"1"	""	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01997"	"7247"	"ENSG00000211460"	"TSN"	"B7Z3X8; hsa:7247; Q15631; Q5U0K7"	""	"Small interfering RNA (siRNA) biogenesis"	"1"	"0"	"26.0"	"28.7"	"33.5"	"28.7"	"25.4"	"26.0"	"33.2"	"75.9"	"70.1"	"163.4"	"285.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WUW1"	"Protein BRICK1 OS=Homo sapiens OX=9606 GN=BRK1 PE=1 SV=1"	"0.000"	""	"19"	"1"	"1"	"1"	"75"	"8.7"	"5.45"	"508.17"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	""	"55845"	"ENSG00000254999"	"BRK1"	"B2R5E2; hsa:55845; Q8WUW1; Q9P082"	"Regulation of actin cytoskeleton"	"RAC1 GTPase cycle; VEGFA-VEGFR2 Pathway; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; RAC2 GTPase cycle; RAC3 GTPase cycle"	"8"	"0"	"21.9"	"13.0"	"18.8"	"21.3"	"12.5"	"16.3"	"28.7"	"72.4"	"84.0"	"232.2"	"352.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y365"	"START domain-containing protein 10 OS=Homo sapiens OX=9606 GN=STARD10 PE=1 SV=2"	"0.000"	""	"5"	"1"	"1"	"1"	"291"	"33.0"	"7.12"	"507.57"	""	"1"	""	"transport"	"other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf01852"	"10809"	"ENSG00000214530"	"STARD10"	"hsa:10809; O60532; Q9Y365"	""	"Synthesis of PC"	"1"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"19.6"	"22.4"	"137.4"	"148.2"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UH92"	"Max-like protein X OS=Homo sapiens OX=9606 GN=MLX PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"298"	"33.3"	"8.06"	"502.93"	""	"1"	""	"other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00010"	"6945"	"ENSG00000108788"	"MLX"	"A8K2J3; B2RAV8; B2RD73; hsa:6945; Q53XM6; Q96FL2; Q9H2V0; Q9H2V1; Q9H2V2; Q9NXN3; Q9UH92"	"Nonalcoholic fatty liver disease"	"ChREBP activates metabolic gene expression"	"2"	"0"	"89.8"	"120.9"	"21.7"	"170.7"	"102.4"	"86.9"	"158.4"	"1080.9"	"240.9"	"1395.1"	"182.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92615"	"La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3"	"0.000"	""	"2"	"1"	"1"	"1"	"738"	"80.5"	"6.92"	"501.43"	""	"1"	""	"other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity"	"Pf05383"	"23185"	"ENSG00000107929"	"LARP4B"	"A7MD20; hsa:23185; Q5T3R3; Q5T3R4; Q5T3R5; Q68CY4; Q92615"	""	""	"0"	"0"	"28.8"	"25.6"	"28.1"	"33.4"	"27.2"	"29.4"	"37.3"	"52.7"	"58.8"	"99.9"	"115.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96SN8"	"CDK5 regulatory subunit-associated protein 2 OS=Homo sapiens OX=9606 GN=CDK5RAP2 PE=1 SV=5"	"0.000"	""	"1"	"2"	"2"	"2"	"1893"	"214.9"	"5.58"	"495.38"	""	"2"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf07989"	"55755"	"ENSG00000136861"	"CDK5RAP2"	"hsa:55755; Q5JV18; Q7Z3L4; Q7Z3U1; Q7Z7I6; Q96SN8; Q9BSW0; Q9H6J6; Q9HCD9; Q9NV90; Q9UIW9"	""	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"7"	"0"	"62.2"	"40.6"	"54.6"	"55.1"	"58.2"	"57.7"	"70.2"	"101.2"	"108.8"	"260.2"	"330.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00165"	"HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2"	"0.000"	""	"5"	"2"	"2"	"2"	"279"	"31.6"	"4.92"	"493.73"	""	"2"	""	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"other molecular function"	""	"10456"	"ENSG00000143575"	"HAX1"	"A8W4W9; A8W4X0; B4DUJ7; hsa:10456; O00165; Q5VYD5; Q5VYD7; Q96AU4; Q9BS80"	"Primary ovarian insufficiency"	""	"1"	"0"	"219.5"	"169.6"	"208.4"	"201.2"	"167.8"	"214.1"	"245.4"	"408.7"	"402.7"	"1050.1"	"1426.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6PIJ6"	"F-box only protein 38 OS=Homo sapiens OX=9606 GN=FBXO38 PE=1 SV=3"	"0.000"	""	"1"	"1"	"1"	"1"	"1188"	"133.9"	"6.33"	"487.72"	""	"1"	""	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf00646"	"81545"	"ENSG00000145868"	"FBXO38"	"hsa:81545; Q6PIJ6; Q6PK72; Q7Z2U0; Q86VN3; Q9BXY6; Q9H837; Q9HC40"	""	""	"0"	"0"	"2.7"	"3.6"	"7.0"	"2.2"	"0.0"	"3.4"	"6.2"	"10.1"	"12.6"	"47.3"	"96.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50402"	"Emerin OS=Homo sapiens OX=9606 GN=EMD PE=1 SV=1"	"0.000"	""	"4"	"1"	"1"	"1"	"254"	"29.0"	"5.50"	"484.82"	""	"1"	""	"cell organization and biogenesis;other biological processes"	"other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity"	"Pf03020"	"2010"	"ENSG00000102119"	"EMD"	"hsa:2010; P50402; Q6FI02"	"Arrhythmogenic right ventricular cardiomyopathy; Envelope proteins and their potential roles in EDMD physiopathology; Influence of laminopathies on Wnt signaling"	"Initiation of Nuclear Envelope (NE) Reformation; Depolymerization of the Nuclear Lamina; RHOG GTPase cycle; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOD GTPase cycle; Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"	"12"	"0"	"129.5"	"123.7"	"99.9"	"112.4"	"109.6"	"118.4"	"136.0"	"218.0"	"218.0"	"428.6"	"627.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94927"	"HAUS augmin-like complex subunit 5 OS=Homo sapiens OX=9606 GN=HAUS5 PE=1 SV=2"	"0.000"	""	"2"	"1"	"1"	"1"	"633"	"71.6"	"8.51"	"481.27"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton"	""	"Pf14817"	"23354"	"ENSG00000249115"	"HAUS5"	"B2RXK1; hsa:23354; O94927; Q6P2P7; Q7L3D5; Q96CT8"	""	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"7"	"0"	"55.1"	"43.3"	"36.0"	"40.9"	"40.6"	"41.1"	"57.8"	"103.2"	"95.4"	"192.9"	"261.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43741"	"5'-AMP-activated protein kinase subunit beta-2 OS=Homo sapiens OX=9606 GN=PRKAB2 PE=1 SV=1"	"0.000"	""	"4"	"1"	"1"	"1"	"272"	"30.3"	"6.46"	"481.23"	""	"1"	""	"other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf04739, Pf16561"	"5565"	"ENSG00000131791"	"PRKAB2"	"A8K9V5; B4DH06; hsa:5565; O43741; Q5VXY0"	"AMP-activated protein kinase signaling; Target of rapamycin signaling; Energy metabolism; Sterol regulatory element-binding proteins (SREBP) signaling; Angiopoietin-like protein 8 regulatory pathway; Lipid metabolism pathway; Caloric restriction and aging; Thermogenesis; Nonalcoholic fatty liver disease; Synaptic signaling pathways associated with autism spectrum disorder; Hippo signaling regulation pathways; 1q21.1 copy number variation syndrome; Autophagy; p53 transcriptional gene network; Pleural mesothelioma"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Activation of AMPK downstream of NMDARs; Regulation of TP53 Activity through Phosphorylation; TP53 Regulates Metabolic Genes; Carnitine metabolism; Macroautophagy; Energy dependent regulation of mTOR by LKB1-AMPK; AMPK inhibits chREBP transcriptional activation activity; Activation of PPARGC1A (PGC-1alpha) by phosphorylation; Lipophagy"	"25"	"0"	"22.2"	"16.7"	"13.3"	"12.0"	"9.4"	"12.5"	"23.2"	"78.8"	"94.9"	"435.7"	"886.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60658"	"High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A OS=Homo sapiens OX=9606 GN=PDE8A PE=1 SV=2"	"0.000"	""	"2"	"1"	"1"	"1"	"829"	"93.2"	"6.11"	"480.25"	""	"1"	""	"other metabolic processes;signal transduction;other biological processes"	"cytosol"	"enzyme regulator activity;other molecular function"	"Pf00233, Pf00989"	"5151"	"ENSG00000073417"	"PDE8A"	"B3KXE6; H0YMZ7; hsa:5151; O60658; Q6P9H3; Q969I1; Q96PC9; Q96PD0; Q96PD1; Q96T71; Q9UMB7; Q9UMC3"	"G protein signaling pathways; Phosphodiesterases in neuronal function; 15q25 copy number variation"	"G alpha (s) signalling events"	"4"	"0"	"23.6"	"22.5"	"28.0"	"29.4"	"23.2"	"31.1"	"31.3"	"74.4"	"68.4"	"148.3"	"197.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96JJ7"	"Protein disulfide-isomerase TMX3 OS=Homo sapiens OX=9606 GN=TMX3 PE=1 SV=2"	"0.000"	""	"3"	"1"	"1"	"1"	"454"	"51.8"	"4.91"	"448.67"	""	"1"	""	"protein metabolism;other metabolic processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf00085, Pf13848"	"54495"	"ENSG00000166479"	"TMX3"	"B3KV75; hsa:54495; Q52LT7; Q8N5J0; Q96JJ7; Q9NWJ9"	""	"Platelet degranulation"	"1"	"0"	"16.7"	"15.6"	"19.5"	"12.1"	"13.9"	"18.8"	"17.6"	"32.5"	"37.1"	"77.0"	"98.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22694"	"cAMP-dependent protein kinase catalytic subunit beta OS=Homo sapiens OX=9606 GN=PRKACB PE=1 SV=2"	"0.000"	""	"3"	"1"	"1"	"1"	"351"	"40.6"	"8.78"	"446.46"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"5567"	"ENSG00000142875"	"PRKACB"	"B1APG4; B4DKB0; B4E2Q1; hsa:5567; P22694; Q14VH1; Q59GC0; Q5BNE9; Q5BNF0; Q5BNF1; Q5BNF2; Q5BNF3; Q5CZ92; Q5T1K3; Q7Z3M1; Q8IYR5; Q8IZQ0; Q96B09"	"AMP-activated protein kinase signaling; Dopamine metabolism; Common pathways underlying drug addiction; Myometrial relaxation and contraction pathways; G protein signaling pathways; MAPK signaling pathway; Cannabinoid receptor signaling; Chemokine signaling pathway; Lipid metabolism pathway; Ras signaling; Hedgehog signaling pathway; Thermogenesis; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; GPR143 in melanocytes and retinal pigment epithelium cells; Cardiomyocyte signaling pathways converging on Titin; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"FCGR3A-mediated IL10 synthesis; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; MAPK6/MAPK4 signaling; Triglyceride catabolism; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production; RET signaling; VEGFA-VEGFR2 Pathway; Factors involved in megakaryocyte development and platelet production; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Vasopressin regulates renal water homeostasis via Aquaporins; PKA activation; PKA activation in glucagon signalling; Regulation of glycolysis by fructose 2,6-bisphosphate metabolism; CD209 (DC-SIGN) signaling; Rap1 signalling; HDL assembly; DARPP-32 events; CREB1 phosphorylation through the activation of Adenylate Cyclase; ROBO receptors bind AKAP5; PKA-mediated phosphorylation of key metabolic factors"	"44"	"0"	"30.9"	"23.5"	"33.2"	"37.5"	"27.2"	"24.2"	"37.5"	"52.7"	"49.3"	"111.6"	"151.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6DKI1"	"60S ribosomal protein L7-like 1 OS=Homo sapiens OX=9606 GN=RPL7L1 PE=1 SV=2"	"0.000"	""	"4"	"1"	"1"	"1"	"255"	"29.7"	"10.52"	"443.89"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes;developmental processes"	"cytosol;translational apparatus;nucleus"	"other molecular function"	"Pf00327, Pf08079"	"285855"	"ENSG00000146223"	"RPL7L1"	"A8K7D4; B7Z652; hsa:285855; Q5TFZ5; Q6DKI1; Q6PEK3"	""	""	"0"	"0"	"73.8"	"69.4"	"76.5"	"69.4"	"63.4"	"66.6"	"92.2"	"114.5"	"110.4"	"213.0"	"295.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P45974"	"Ubiquitin carboxyl-terminal hydrolase 5 OS=Homo sapiens OX=9606 GN=USP5 PE=1 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"858"	"95.7"	"5.03"	"441.42"	""	"1"	""	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle"	"other molecular function"	"Pf00443, Pf00627, Pf02148, Pf17807"	"8078"	"ENSG00000111667"	"USP5"	"D3DUS7; D3DUS8; hsa:8078; P45974; Q96J22"	"IL-18 signaling pathway"	"Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Ub-specific processing proteases"	"3"	"0"	"7.3"	"3.3"	"7.5"	"3.5"	"7.4"	"10.1"	"11.3"	"11.4"	"14.3"	"21.8"	"27.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46734"	"Dual specificity mitogen-activated protein kinase kinase 3 OS=Homo sapiens OX=9606 GN=MAP2K3 PE=1 SV=2"	"0.000"	""	"3"	"1"	"1"	"1"	"347"	"39.3"	"7.43"	"439.40"	""	"1"	""	"protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"5606"	"ENSG00000034152"	"MAP2K3"	"B3KSK7; hsa:5606; P46734; Q99441; Q9UE71; Q9UE72"	"Physiological and pathological hypertrophy of the heart; MicroRNAs in cardiomyocyte hypertrophy; Integrin-mediated cell adhesion; IL-1 signaling pathway; Thyroid stimulating hormone (TSH) signaling pathway; Glioblastoma signaling pathways; TNF-alpha signaling pathway; Interleukin-1 (IL-1) structural pathway; Cardiac hypertrophic response; Endoderm differentiation; MAPK signaling pathway; 4-hydroxytamoxifen, dexamethasone, and retinoic acids regulation of p27 expression; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Embryonic stem cell pluripotency pathways; MAPK cascade; Epithelial to mesenchymal transition in colorectal cancer; Thermogenesis; Vitamin D in inflammatory diseases; Signal transduction through IL1R; Translation inhibitors in chronically activated PDGFRA cells; Hepatitis B infection; Insulin signaling; Host-pathogen interaction of human coronaviruses - MAPK signaling; 16p11.2 proximal deletion syndrome; Pleural mesothelioma; Interferon type I signaling pathways; Serotonin HTR1 group and FOS pathway; Toll-like receptor signaling pathway"	"Oxidative Stress Induced Senescence; activated TAK1 mediates p38 MAPK activation"	"31"	"0"	"26.1"	"30.6"	"26.9"	"22.9"	"27.4"	"30.0"	"27.1"	"96.2"	"103.2"	"175.8"	"218.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6YN16"	"Hydroxysteroid dehydrogenase-like protein 2 OS=Homo sapiens OX=9606 GN=HSDL2 PE=1 SV=1"	"0.000"	""	"4"	"1"	"1"	"1"	"418"	"45.4"	"7.99"	"439.39"	""	"1"	""	""	"mitochondrion;other cytoplasmic organelle"	"other molecular function"	"Pf00106, Pf02036"	"84263"	"ENSG00000119471"	"HSDL2"	"A8K1L4; A8K8X1; A8MSV3; hsa:84263; Q658M8; Q6YN16; Q9BT58"	""	""	"0"	"0"	"90.3"	"67.5"	"82.5"	"75.1"	"66.1"	"81.1"	"96.2"	"129.1"	"137.6"	"248.8"	"341.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HAF1"	"Chromatin modification-related protein MEAF6 OS=Homo sapiens OX=9606 GN=MEAF6 PE=1 SV=1"	"0.000"	""	"7"	"1"	"1"	"1"	"191"	"21.6"	"9.32"	"438.93"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf09340"	"64769"	"ENSG00000163875"	"MEAF6"	"B1AK64; hsa:64769; Q4F967; Q7Z311; Q86WE3; Q9HAF1"	""	"HATs acetylate histones; Regulation of TP53 Activity through Acetylation"	"2"	"0"	"19.4"	"13.7"	"19.5"	"9.6"	"8.4"	"13.4"	"21.7"	"25.6"	"14.9"	"28.1"	"22.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49674"	"Casein kinase I isoform epsilon OS=Homo sapiens OX=9606 GN=CSNK1E PE=1 SV=1"	"0.000"	""	"3"	"1"	"1"	"1"	"416"	"47.3"	"9.66"	"431.05"	""	"1"	""	"cell-cell signaling;protein metabolism;DNA metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"102800317; 1454"	"ENSG00000213923"	"CSNK1E"	"hsa:102800317; hsa:1454; P49674"	"Alzheimer's disease and miRNA effects; Melatonin metabolism and effects; Wnt signaling pathway; Wnt signaling pathway and pluripotency; Hedgehog signaling pathway; lncRNA in canonical Wnt signaling and colorectal cancer; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Pleural mesothelioma; Alzheimer's disease"	"Major pathway of rRNA processing in the nucleolus and cytosol; WNT mediated activation of DVL; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Circadian Clock"	"20"	"0"	"12.8"	"12.1"	"13.8"	"14.1"	"16.5"	"14.5"	"22.5"	"28.9"	"32.5"	"80.8"	"114.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BV44"	"THUMP domain-containing protein 3 OS=Homo sapiens OX=9606 GN=THUMPD3 PE=1 SV=1"	"0.000"	""	"3"	"1"	"1"	"1"	"507"	"57.0"	"6.37"	"429.90"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01170, Pf02926"	"25917"	"ENSG00000134077"	"THUMPD3"	"hsa:25917; Q9BV44; Q9H8V6; Q9NVC1; Q9UFS3"	""	""	"0"	"0"	"2.4"	"3.0"	"3.7"	"2.6"	"3.7"	"3.2"	"9.0"	"9.5"	"12.5"	"41.5"	"83.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N3F8"	"MICAL-like protein 1 OS=Homo sapiens OX=9606 GN=MICALL1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"863"	"93.4"	"7.25"	"428.57"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"other membranes;other cytoplasmic organelle"	"other molecular function"	"Pf00307, Pf00412, Pf12130"	"85377"	"ENSG00000100139"	"MICALL1"	"hsa:85377; Q5TI16; Q7RTP5; Q8N3F8; Q8N3N8; Q9BVL9; Q9BY92; Q9UH43; Q9UH44; Q9UH45"	""	""	"0"	"0"	"11.2"	"7.2"	"10.3"	"6.5"	"7.4"	"11.2"	"10.3"	"30.0"	"25.9"	"51.7"	"44.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q969F1"	"General transcription factor 3C polypeptide 6 OS=Homo sapiens OX=9606 GN=GTF3C6 PE=1 SV=1"	"0.000"	""	"8"	"1"	"1"	"1"	"213"	"24.0"	"4.21"	"428.15"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf10419"	"112495"	"ENSG00000155115"	"GTF3C6"	"hsa:112495; Q5VXN2; Q969F1"	""	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter"	"3"	"0"	"22.9"	"31.8"	"32.6"	"28.4"	"22.4"	"24.5"	"41.6"	"92.2"	"112.9"	"295.3"	"374.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96GM5"	"SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 OS=Homo sapiens OX=9606 GN=SMARCD1 PE=1 SV=2"	"0.000"	""	"4"	"1"	"1"	"1"	"515"	"58.2"	"9.25"	"422.65"	""	"1"	""	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf02201"	"6602"	"ENSG00000066117"	"SMARCD1"	"A6NN27; hsa:6602; Q92924; Q96GM5; Q9Y635"	"Androgen receptor network in prostate cancer; Tumor suppressor activity of SMARCB1; Thermogenesis; Kleefstra syndrome"	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; RMTs methylate histone arginines"	"6"	"0"	"19.4"	"18.5"	"19.5"	"15.9"	"20.1"	"28.7"	"25.4"	"55.6"	"38.1"	"89.4"	"104.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKG9"	"Peroxisomal carnitine O-octanoyltransferase OS=Homo sapiens OX=9606 GN=CROT PE=1 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"612"	"70.1"	"7.08"	"421.36"	""	"1"	""	"other metabolic processes;transport"	"cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00755"	"54677"	"ENSG00000005469"	"CROT"	"A4D1D6; E7EQF2; hsa:54677; Q86V17; Q8IUW9; Q9UKG9; Q9Y6I2"	""	"Peroxisomal protein import; Beta-oxidation of pristanoyl-CoA"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HBM1"	"Kinetochore protein Spc25 OS=Homo sapiens OX=9606 GN=SPC25 PE=1 SV=1"	"0.000"	""	"6"	"1"	"1"	"1"	"224"	"26.1"	"8.00"	"416.79"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf08234"	"57405"	"ENSG00000152253; ENSG00000277909"	"SPC25"	"A8K4X8; D3DPC0; hsa:57405; Q9HBM1"	""	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"6"	"0"	"12.9"	"10.0"	"7.2"	"11.1"	"14.1"	"8.2"	"8.1"	"17.5"	"22.6"	"33.6"	"29.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6NUQ4"	"Transmembrane protein 214 OS=Homo sapiens OX=9606 GN=TMEM214 PE=1 SV=2"	"0.000"	""	"2"	"1"	"1"	"1"	"689"	"77.1"	"9.14"	"416.35"	""	"1"	""	"other biological processes"	"other membranes;cytosol;cytoskeleton;ER/Golgi"	""	"Pf10151"	"54867"	"ENSG00000119777"	"TMEM214"	"A6NNF2; B3KUI9; B5MCD8; D6W547; hsa:54867; Q53SW1; Q69YH4; Q6NUQ4; Q8NC45; Q8WZ37; Q9NXH2"	""	""	"0"	"0"	"241.3"	"237.4"	"198.4"	"193.0"	"179.0"	"194.3"	"249.9"	"334.6"	"318.3"	"475.6"	"630.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NPL8"	"Complex I assembly factor TIMMDC1, mitochondrial OS=Homo sapiens OX=9606 GN=TIMMDC1 PE=1 SV=2"	"0.000"	""	"4"	"1"	"1"	"1"	"285"	"32.2"	"8.50"	"412.28"	""	"1"	""	""	"other membranes;mitochondrion;nucleus"	""	"Pf02466"	"51300"	"ENSG00000113845"	"TIMMDC1"	"D3DN81; hsa:51300; Q6IAJ7; Q6UWU6; Q9NPL8; Q9NPR3; Q9NPS5; Q9P0Y6"	""	"Complex I biogenesis"	"1"	"0"	"89.6"	"82.8"	"78.4"	"71.7"	"78.9"	"84.5"	"100.3"	"153.9"	"146.4"	"283.7"	"385.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q53GS7"	"Nucleoporin GLE1 OS=Homo sapiens OX=9606 GN=GLE1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"1"	"1"	"698"	"79.8"	"7.43"	"410.70"	""	"1"	""	"other metabolic processes;transport"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf07817"	"2733"	"ENSG00000119392"	"GLE1"	"hsa:2733; O75458; Q53GS7; Q53GT9; Q5VVU1; Q8NCP6; Q9UFL6"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript"	"1"	"0"	"14.3"	"13.4"	"11.3"	"9.6"	"13.1"	"13.1"	"15.4"	"31.7"	"35.4"	"86.8"	"147.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H098"	"Protein FAM107B OS=Homo sapiens OX=9606 GN=FAM107B PE=1 SV=1"	"0.000"	""	"8"	"1"	"1"	"1"	"131"	"15.5"	"8.29"	"408.97"	""	"1"	""	""	""	""	"Pf06625"	"83641"	"ENSG00000065809"	"FAM107B"	"A8K1P4; D3DRT2; hsa:83641; Q5T9K7; Q5T9K8; Q6ZSI4; Q9H098"	""	""	"0"	"0"	"37.0"	"33.7"	"37.2"	"32.4"	"37.4"	"36.9"	"41.2"	"104.2"	"123.1"	"294.1"	"336.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15460"	"Prolyl 4-hydroxylase subunit alpha-2 OS=Homo sapiens OX=9606 GN=P4HA2 PE=1 SV=1"	"0.000"	""	"2"	"1"	"1"	"1"	"535"	"60.9"	"5.71"	"407.46"	""	"1"	""	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf08336, Pf13640"	"8974"	"ENSG00000072682"	"P4HA2"	"D3DQ85; D3DQ86; hsa:8974; O15460; Q8WWN0"	"VEGFA-VEGFR2 signaling; Amino acid metabolism; Type I collagen synthesis in the context of osteogenesis imperfecta"	"Collagen biosynthesis and modifying enzymes"	"4"	"0"	"8.1"	"6.7"	"4.2"	"7.1"	"7.8"	"4.4"	"8.9"	"16.0"	"15.3"	"30.7"	"55.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6X9"	"ATPase MORC2 OS=Homo sapiens OX=9606 GN=MORC2 PE=1 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"1032"	"117.8"	"8.38"	"392.65"	""	"1"	""	"cell organization and biogenesis;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf07496, Pf13589, Pf17942"	"22880"	"ENSG00000133422"	"MORC2"	"B2RNB1; hsa:22880; Q9UF28; Q9Y6V2; Q9Y6X9"	""	"Fatty acyl-CoA biosynthesis"	"1"	"0"	"10.5"	"11.7"	"14.8"	"14.1"	"13.2"	"14.0"	"16.9"	"30.7"	"31.6"	"69.0"	"90.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P04818"	"Thymidylate synthase OS=Homo sapiens OX=9606 GN=TYMS PE=1 SV=3"	"0.000"	""	"6"	"1"	"1"	"1"	"313"	"35.7"	"7.01"	"385.96"	""	"1"	""	"DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"other membranes;cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00303"	"7298"	"ENSG00000176890"	"TYMS"	"hsa:7298; P04818; Q8WYK3; Q8WYK4"	"Fluoropyrimidine activity; One-carbon metabolism; Retinoblastoma gene in cancer; Trans-sulfuration, one-carbon metabolism and related pathways; Ethanol effects on histone modifications; Pyrimidine metabolism"	"Interconversion of nucleotide di- and triphosphates; G1/S-Specific Transcription"	"8"	"0"	"4.9"	"2.4"	"3.2"	"4.7"	"5.1"	"7.4"	"5.4"	"8.0"	"12.8"	"29.4"	"67.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96S15"	"GATOR complex protein WDR24 OS=Homo sapiens OX=9606 GN=WDR24 PE=1 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"790"	"88.2"	"6.52"	"365.07"	""	"1"	""	"other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	""	"Pf00400"	"84219"	"ENSG00000127580"	"WDR24"	"A2IDB8; D3DU59; hsa:84219; Q96GC7; Q96S15; Q9H0B7"	""	"Amino acids regulate mTORC1"	"1"	"0"	"14.2"	"10.2"	"16.3"	"13.7"	"15.5"	"16.9"	"17.8"	"19.0"	"20.9"	"32.0"	"33.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9ULX3"	"RNA-binding protein NOB1 OS=Homo sapiens OX=9606 GN=NOB1 PE=1 SV=1"	"0.000"	""	"4"	"1"	"1"	"1"	"412"	"46.6"	"7.18"	"365.02"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf08772, Pf15017, Pf17146"	"28987"	"ENSG00000141101"	"NOB1"	"hsa:28987; Q7L6B7; Q7M4M4; Q7Z4B5; Q9NWB0; Q9ULX3"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9ULW0"	"Targeting protein for Xklp2 OS=Homo sapiens OX=9606 GN=TPX2 PE=1 SV=2"	"0.000"	""	"3"	"1"	"1"	"1"	"747"	"85.6"	"9.23"	"362.24"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf06886, Pf09041, Pf12214"	"22974"	"ENSG00000088325"	"TPX2"	"hsa:22974; Q96RR5; Q9H1R4; Q9NRA3; Q9UFN9; Q9UL00; Q9ULW0; Q9Y2M1"	"Gastric cancer network 1"	"AURKA Activation by TPX2; Regulation of TP53 Activity through Phosphorylation"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14192"	"Four and a half LIM domains protein 2 OS=Homo sapiens OX=9606 GN=FHL2 PE=1 SV=3"	"0.000"	""	"4"	"1"	"1"	"1"	"279"	"32.2"	"7.55"	"360.08"	""	"1"	""	"developmental processes;other biological processes"	"cytoskeleton;nucleus"	"other molecular function"	"Pf00412"	"2274"	"ENSG00000115641"	"FHL2"	"hsa:2274; Q13229; Q13644; Q14192; Q2I5I4; Q5TM15; Q9P294"	"Androgen receptor signaling pathway; RANKL/RANK signaling pathway; Ectoderm differentiation; VEGFA-VEGFR2 signaling"	"PPARA activates gene expression"	"5"	"0"	"99.0"	"82.8"	"60.8"	"75.3"	"58.6"	"67.4"	"101.9"	"145.5"	"138.5"	"229.8"	"295.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UJX4"	"Anaphase-promoting complex subunit 5 OS=Homo sapiens OX=9606 GN=ANAPC5 PE=1 SV=2"	"0.000"	""	"2"	"1"	"1"	"1"	"755"	"85.0"	"6.87"	"356.15"	""	"1"	""	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus"	"other molecular function"	"Pf12862"	"51433"	"ENSG00000089053"	"ANAPC5"	"E9PFB2; hsa:51433; Q8N4H7; Q9BQD4; Q9UJX4"	"Cell cycle"	"Separation of Sister Chromatids; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Inactivation of APC/C via direct inhibition of the APC/C complex; APC-Cdc20 mediated degradation of Nek2A; Antigen processing: Ubiquitination & Proteasome degradation; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; CDK-mediated phosphorylation and removal of Cdc6; Autodegradation of Cdh1 by Cdh1:APC/C; Assembly of the pre-replicative complex; APC/C:Cdc20 mediated degradation of Cyclin B; Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase; Regulation of APC/C activators between G1/S and early anaphase; Phosphorylation of the APC/C; Senescence-Associated Secretory Phenotype (SASP); Transcriptional Regulation by VENTX; Aberrant regulation of mitotic exit in cancer due to RB1 defects"	"19"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P287"	"BRCA2 and CDKN1A-interacting protein OS=Homo sapiens OX=9606 GN=BCCIP PE=1 SV=1"	"0.000"	""	"5"	"1"	"1"	"1"	"314"	"36.0"	"4.61"	"353.51"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus"	"enzyme regulator activity;cytoskeletal activity"	"Pf13862"	"56647"	"ENSG00000107949"	"BCCIP"	"B3KP45; hsa:56647; Q8ND15; Q96GC4; Q9P287; Q9P288"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2R4"	"Probable ATP-dependent RNA helicase DDX52 OS=Homo sapiens OX=9606 GN=DDX52 PE=1 SV=3"	"0.000"	""	"2"	"1"	"1"	"1"	"599"	"67.5"	"9.67"	"345.84"	""	"1"	""	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"5.7"	"4.2"	"8.0"	"3.4"	"1.9"	"5.3"	"6.6"	"11.0"	"14.0"	"29.6"	"40.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6DN90"	"IQ motif and SEC7 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=IQSEC1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"1"	"1"	"963"	"108.2"	"6.93"	"338.27"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf01369, Pf16453"	"9922"	"ENSG00000144711"	"IQSEC1"	"A0A087WWK8; hsa:9922; O94863; Q6DN90; Q96D85"	"EGF/EGFR signaling pathway"	""	"1"	"0"	"34.7"	"24.7"	"36.9"	"43.7"	"31.6"	"43.5"	"49.9"	"91.2"	"97.8"	"112.7"	"141.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95625"	"Zinc finger and BTB domain-containing protein 11 OS=Homo sapiens OX=9606 GN=ZBTB11 PE=1 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"1053"	"119.3"	"8.66"	"332.83"	""	"1"	""	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00096, Pf00651, Pf13912, Pf17921"	"27107"	"ENSG00000066422"	"ZBTB11"	"hsa:27107; O95625; Q2NKP9"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86W56"	"Poly(ADP-ribose) glycohydrolase OS=Homo sapiens OX=9606 GN=PARG PE=1 SV=1"	"0.000"	""	"1"	"1"	"1"	"1"	"976"	"111.0"	"6.43"	"331.60"	""	"1"	""	"DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf05028"	"670; 8505"	"ENSG00000227345"	"PARG"	"A5YBK3; B2RC24; B4DIU5; B4DYR4; hsa:8505; I6RUV3; Q6E4P6; Q6E4P7; Q7Z742; Q86W56; Q9Y4W7"	"10q11.21q11.23 copy number variation syndrome"	"POLB-Dependent Long Patch Base Excision Repair"	"2"	"0"	"15.9"	"12.9"	"13.9"	"15.0"	"17.8"	"13.6"	"18.8"	"47.2"	"49.0"	"104.9"	"144.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14646"	"Chromodomain-helicase-DNA-binding protein 1 OS=Homo sapiens OX=9606 GN=CHD1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"1710"	"196.6"	"7.14"	"328.68"	""	"1"	""	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf00385, Pf13907, Pf18375"	"1105"	"ENSG00000153922"	"CHD1"	"hsa:1105; O14646; Q17RZ3"	""	"Estrogen-dependent gene expression"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VZL5"	"Zinc finger MYM-type protein 4 OS=Homo sapiens OX=9606 GN=ZMYM4 PE=1 SV=1"	"0.000"	""	"1"	"1"	"1"	"1"	"1548"	"172.7"	"6.84"	"321.15"	""	"1"	""	"cell organization and biogenesis;other biological processes"	""	"nucleic acid binding activity;other molecular function"	"Pf06467, Pf12012"	"9202"	"ENSG00000146463"	"ZMYM4"	"A0JP19; A0JP20; hsa:9202; O43308; Q5T5E1; Q5T5E2; Q5VZL5; Q7L3Q4"	""	""	"0"	"0"	"40.0"	"19.6"	"59.7"	"45.4"	"44.5"	"45.0"	"58.3"	"110.8"	"108.1"	"226.3"	"233.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q53GG5"	"PDZ and LIM domain protein 3 OS=Homo sapiens OX=9606 GN=PDLIM3 PE=1 SV=1"	"0.000"	""	"4"	"1"	"1"	"1"	"364"	"39.2"	"6.89"	"319.94"	""	"1"	""	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412, Pf00595, Pf15936"	"27295"	"ENSG00000154553"	"PDLIM3"	"B2R866; hsa:27295; O43590; O60439; O60440; Q53GG5; Q8N6Y6; Q9BVP4"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12766"	"HMG domain-containing protein 3 OS=Homo sapiens OX=9606 GN=HMGXB3 PE=2 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"1538"	"168.2"	"8.05"	"318.09"	""	"1"	""	""	"nucleus"	"nucleic acid binding activity"	""	""	"ENSG00000113716"	"HMGXB3"	"A0A8C8PVR7"	""	""	"0"	"0"	"11.9"	"9.0"	"7.5"	"8.2"	"7.0"	"8.5"	"9.3"	"9.2"	"15.7"	"28.4"	"33.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14527"	"Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"1009"	"113.9"	"8.60"	"316.76"	""	"1"	""	"cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf08797, Pf13923"	"6596"	"ENSG00000071794"	"HLTF"	"D3DNH3; hsa:6596; Q14527; Q14536; Q16051; Q7KYJ6; Q86YA5; Q92652; Q96KM9"	"Retinoblastoma gene in cancer"	"E3 ubiquitin ligases ubiquitinate target proteins"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43920"	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 OS=Homo sapiens OX=9606 GN=NDUFS5 PE=1 SV=3"	"0.000"	""	"7"	"1"	"1"	"1"	"106"	"12.5"	"9.14"	"309.80"	""	"1"	""	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf10200"	"4725"	"ENSG00000168653"	"NDUFS5"	"hsa:4725; O43920"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"174.6"	"98.1"	"162.2"	"124.3"	"129.2"	"164.6"	"163.1"	"207.8"	"174.5"	"273.7"	"459.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99547"	"M-phase phosphoprotein 6 OS=Homo sapiens OX=9606 GN=MPHOSPH6 PE=1 SV=2"	"0.000"	""	"5"	"1"	"1"	"1"	"160"	"19.0"	"5.20"	"308.58"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf10175"	"10200"	"ENSG00000135698"	"MPHOSPH6"	"B2RAF0; hsa:10200; Q99547"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"148.1"	"107.0"	"142.0"	"128.7"	"127.2"	"150.8"	"189.9"	"276.6"	"263.4"	"504.6"	"706.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14493"	"Histone RNA hairpin-binding protein OS=Homo sapiens OX=9606 GN=SLBP PE=1 SV=1"	"0.000"	""	"3"	"1"	"1"	"1"	"270"	"31.3"	"7.47"	"296.97"	""	"1"	""	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf15247"	"7884"	"ENSG00000163950"	"SLBP"	"B3KRJ5; hsa:7884; Q14493"	"8p23.1 copy number variation syndrome; 4p16.3 copy number variation"	"RNA Polymerase II Transcription Termination; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs; Transport of the SLBP Dependant Mature mRNA"	"5"	"0"	"76.2"	"68.7"	"70.6"	"66.2"	"76.3"	"79.6"	"109.3"	"158.1"	"141.1"	"270.9"	"343.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VTQ0"	"Tetratricopeptide repeat protein 39B OS=Homo sapiens OX=9606 GN=TTC39B PE=1 SV=4"	"0.000"	""	"2"	"1"	"1"	"1"	"682"	"76.9"	"7.39"	"293.34"	""	"1"	""	"other metabolic processes;other biological processes"	""	""	"Pf10300"	"158219"	"ENSG00000155158"	"TTC39B"	"A5PLN1; B4DQ10; B4DQX4; B4DW93; hsa:158219; Q5VTQ0; Q8IVR7; Q8IXZ6; Q8N267"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NRR4"	"Ribonuclease 3 OS=Homo sapiens OX=9606 GN=DROSHA PE=1 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"1374"	"159.2"	"7.87"	"292.20"	""	"1"	""	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00035, Pf00636, Pf14622"	"29102"	"ENSG00000113360"	"DROSHA"	"E7EMP9; hsa:29102; Q7Z5V2; Q86YH0; Q9NRR4; Q9NW73; Q9Y2V9; Q9Y4Y0"	"miRNA biogenesis; exRNA mechanism of action and biogenesis; DDX1 as a regulatory component of the Drosha microprocessor; 22q11.2 copy number variation syndrome"	"MicroRNA (miRNA) biogenesis"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P32780"	"General transcription factor IIH subunit 1 OS=Homo sapiens OX=9606 GN=GTF2H1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"1"	"1"	"548"	"62.0"	"8.66"	"291.59"	""	"1"	""	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus"	"other molecular function"	"Pf03909, Pf08567"	"2965"	"ENSG00000110768; ENSG00000288114"	"GTF2H1"	"B3KXE0; D3DQY2; hsa:2965; P32780; Q6I9Y7; Q9H5K5; Q9NQD9"	"Eukaryotic transcription initiation; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Dual Incision in GG-NER"	"33"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N4T8"	"Carbonyl reductase family member 4 OS=Homo sapiens OX=9606 GN=CBR4 PE=1 SV=3"	"0.000"	""	"3"	"1"	"1"	"1"	"237"	"25.3"	"9.33"	"289.74"	""	"1"	""	"cell organization and biogenesis;other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf13561"	"84869"	"ENSG00000145439"	"CBR4"	"hsa:84869; Q8N4T8; Q8WTW8; Q96K93"	""	"Fatty acyl-CoA biosynthesis"	"1"	"0"	"83.6"	"77.1"	"84.1"	"79.0"	"89.7"	"90.4"	"105.2"	"136.8"	"138.7"	"238.5"	"276.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VX52"	"Spermatogenesis-associated protein 1 OS=Homo sapiens OX=9606 GN=SPATA1 PE=2 SV=4"	"0.000"	""	"2"	"1"	"1"	"1"	"459"	"52.9"	"8.85"	"289.57"	""	"1"	""	""	"other cell component"	""	"Pf15743"	"100505741"	""	"SPATA1"	"A0A1W2PQB0; A0PJU9; hsa:100505741; Q0VDJ9; Q0VDK0; Q5VX52; Q6P386; Q9HAR4"	""	""	"0"	"0"	"131.7"	"110.7"	"127.7"	"107.9"	"120.2"	"115.4"	"148.0"	"249.8"	"245.1"	"554.1"	"686.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P20810"	"Calpastatin OS=Homo sapiens OX=9606 GN=CAST PE=1 SV=4"	"0.000"	""	"2"	"1"	"1"	"1"	"708"	"76.5"	"5.07"	"286.63"	""	"1"	""	"cell organization and biogenesis;other biological processes"	"other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity"	"Pf00748"	"831"	"ENSG00000153113"	"CAST"	"B7Z468; G5E946; G5E9D3; hsa:831; O95360; P20810; Q05DE8; Q7Z4K0; Q96D08; Q9H1Z5"	""	"Degradation of the extracellular matrix; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"	"2"	"0"	"42.5"	"28.9"	"50.6"	"37.9"	"44.0"	"48.1"	"54.5"	"128.3"	"116.0"	"402.1"	"622.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99504"	"Eyes absent homolog 3 OS=Homo sapiens OX=9606 GN=EYA3 PE=1 SV=3"	"0.000"	""	"2"	"1"	"1"	"1"	"573"	"62.6"	"5.21"	"284.68"	""	"1"	""	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	""	"2140"	"ENSG00000158161"	"EYA3"	"A8K190; B4DIR7; B4DNZ7; hsa:2140; O95463; Q8IVX7; Q99504; Q99813"	""	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IY81"	"pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 OS=Homo sapiens OX=9606 GN=FTSJ3 PE=1 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"847"	"96.5"	"8.40"	"282.34"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf01728, Pf07780, Pf11861"	"117246"	"ENSG00000108592"	"FTSJ3"	"B2RCA5; D3DU22; hsa:117246; Q8IY81; Q8N3A3; Q8WXX1; Q9BWM4; Q9NXT6"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"66.7"	"41.9"	"68.1"	"60.3"	"65.0"	"79.2"	"86.7"	"156.0"	"170.5"	"326.2"	"464.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96G25"	"Mediator of RNA polymerase II transcription subunit 8 OS=Homo sapiens OX=9606 GN=MED8 PE=1 SV=2"	"0.000"	""	"3"	"1"	"1"	"1"	"268"	"29.1"	"7.44"	"282.10"	""	"1"	""	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf10232"	"112950"	"ENSG00000159479"	"MED8"	"A9IZ91; A9IZ92; hsa:112950; Q5JUY8; Q96FQ4; Q96G25"	""	"PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; Generic Transcription Pathway"	"3"	"0"	"60.7"	"47.7"	"64.0"	"58.7"	"61.7"	"64.5"	"70.9"	"140.4"	"120.8"	"326.3"	"396.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WV99"	"AN1-type zinc finger protein 2B OS=Homo sapiens OX=9606 GN=ZFAND2B PE=1 SV=1"	"0.000"	""	"3"	"1"	"1"	"1"	"257"	"28.0"	"6.92"	"280.33"	""	"1"	""	"protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf01428, Pf02809"	"130617"	"ENSG00000158552"	"ZFAND2B"	"hsa:130617; Q8NB98; Q8WV99"	""	""	"0"	"0"	"36.3"	"34.2"	"26.8"	"28.4"	"29.4"	"30.9"	"36.1"	"56.8"	"56.7"	"105.3"	"105.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UI08"	"Ena/VASP-like protein OS=Homo sapiens OX=9606 GN=EVL PE=1 SV=2"	"0.000"	""	"4"	"1"	"1"	"1"	"416"	"44.6"	"8.84"	"278.86"	""	"1"	""	"cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00568, Pf08776"	"51466"	"ENSG00000196405"	"EVL"	"A8K105; B7Z3I5; hsa:51466; O95884; Q7Z522; Q8TBV1; Q9UF25; Q9UI08; Q9UIC2"	""	"RHO GTPases Activate Formins; Generation of second messenger molecules; Signaling by ROBO receptors"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15435"	"Protein phosphatase 1 regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PPP1R7 PE=1 SV=1"	"0.000"	""	"3"	"1"	"1"	"1"	"360"	"41.5"	"4.91"	"276.79"	""	"1"	""	"other biological processes"	"other cell component"	"enzyme regulator activity"	"Pf14580"	"5510"	"ENSG00000115685"	"PPP1R7"	"B4DFD4; B5MCY6; hsa:5510; Q15435; Q9UQE5; Q9UQE6; Q9Y6K4"	"2q37 copy number variation syndrome"	""	"1"	"0"	"3.1"	"4.3"	"5.9"	"3.5"	"3.7"	"4.2"	"5.5"	"12.5"	"11.6"	"53.0"	"92.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P031"	"Thyroid transcription factor 1-associated protein 26 OS=Homo sapiens OX=9606 GN=CCDC59 PE=1 SV=2"	"0.000"	""	"5"	"1"	"1"	"1"	"241"	"28.7"	"9.88"	"275.90"	""	"1"	""	""	"nucleus"	""	"Pf08524"	"29080"	"ENSG00000133773"	"CCDC59"	"hsa:29080; Q9H2V5; Q9NW62; Q9P031"	""	"Surfactant metabolism"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13572"	"Inositol-tetrakisphosphate 1-kinase OS=Homo sapiens OX=9606 GN=ITPK1 PE=1 SV=2"	"0.000"	""	"3"	"1"	"1"	"1"	"414"	"45.6"	"6.16"	"275.48"	""	"1"	""	"other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol"	"kinase activity;other molecular function"	"Pf05770, Pf17927"	"3705"	"ENSG00000100605; ENSG00000274958"	"ITPK1"	"hsa:3705; Q13572; Q9BTL6; Q9H2E7"	"2q37 copy number variation syndrome"	"Factors involved in megakaryocyte development and platelet production; Synthesis of IP3 and IP4 in the cytosol; Synthesis of pyrophosphates in the cytosol"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P206"	"Uncharacterized protein KIAA1522 OS=Homo sapiens OX=9606 GN=KIAA1522 PE=1 SV=2"	"0.000"	""	"2"	"1"	"1"	"1"	"1035"	"107.0"	"9.73"	"275.47"	""	"1"	""	"other biological processes"	""	""	""	"57648"	"ENSG00000162522"	"KIAA1522"	"B4DQU8; B5MDY0; C9JH84; hsa:57648; Q8TCQ0; Q9P206"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UJ41"	"Rab5 GDP/GTP exchange factor OS=Homo sapiens OX=9606 GN=RABGEF1 PE=1 SV=3"	"0.000"	""	"2"	"1"	"1"	"1"	"491"	"56.9"	"7.02"	"274.48"	""	"1"	""	"protein metabolism;other metabolic processes;transport;signal transduction;other biological processes"	"other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf01754, Pf02204, Pf18151"	"27342"	"ENSG00000154710"	"RABGEF1"	"B4DZM7; hsa:27342; Q3HKR2; Q3HKR3; Q53FG0; Q9UJ41"	"16p11.2 distal deletion syndrome"	"RAB GEFs exchange GTP for GDP on RABs; TBC/RABGAPs"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99576"	"TSC22 domain family protein 3 OS=Homo sapiens OX=9606 GN=TSC22D3 PE=1 SV=2"	"0.000"	""	"7"	"1"	"1"	"1"	"134"	"14.8"	"4.54"	"272.23"	""	"1"	""	"stress response;other biological processes"	"cytosol;nucleus"	""	"Pf01166"	"1831"	"ENSG00000157514"	"TSC22D3"	"hsa:1831; Q5H9S3; Q5JRI9; Q5JRJ2; Q6FIH6; Q8NAI1; Q8WVB9; Q99576; Q9UBN5; Q9UG13"	"Glucocorticoid receptor pathway; Nuclear receptors meta-pathway"	"Stimuli-sensing channels"	"3"	"0"	"21.5"	"13.4"	"25.6"	"17.6"	"23.9"	"19.4"	"25.5"	"51.8"	"49.5"	"91.5"	"109.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6ZU35"	"Capping protein inhibiting regulator of actin dynamics OS=Homo sapiens OX=9606 GN=CRACD PE=1 SV=3"	"0.000"	""	"1"	"1"	"1"	"1"	"1233"	"136.7"	"5.60"	"272.09"	""	"1"	""	"cell organization and biogenesis;other biological processes"	"cytosol"	""	"Pf15262"	"57482"	"ENSG00000109265"	"CRACD"	"hsa:57482; Q6ZU35; Q9NTE2; Q9NTP8; Q9ULK9"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"E9PRG8"	"Uncharacterized protein C11orf98 OS=Homo sapiens OX=9606 GN=C11orf98 PE=4 SV=2"	"0.000"	""	"6"	"1"	"1"	"1"	"123"	"14.2"	"11.53"	"269.24"	""	"1"	""	""	""	""	"Pf17719"	"102288414"	"ENSG00000278615"	"C11orf98"	"A0A0B4J220; E9PRG8; hsa:102288414"	""	""	"0"	"0"	"113.0"	"65.6"	"110.2"	"123.8"	"115.1"	"99.3"	"120.7"	"166.9"	"168.2"	"311.5"	"329.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WVT3"	"Trafficking protein particle complex subunit 12 OS=Homo sapiens OX=9606 GN=TRAPPC12 PE=1 SV=3"	"0.000"	""	"1"	"1"	"1"	"1"	"735"	"79.3"	"4.91"	"266.48"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	""	"Pf14559"	"51112"	"ENSG00000171853"	"TRAPPC12"	"B3KV01; D6W4Y2; hsa:51112; Q8WVT3; Q8WVW1; Q9Y395"	""	"RAB GEFs exchange GTP for GDP on RABs"	"1"	"0"	"9.6"	"4.5"	"6.1"	"9.1"	"8.4"	"5.8"	"7.5"	"31.4"	"35.5"	"98.4"	"158.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92686"	"Neurogranin OS=Homo sapiens OX=9606 GN=NRGN PE=1 SV=1"	"0.000"	""	"19"	"1"	"1"	"1"	"78"	"7.6"	"7.87"	"266.24"	""	"1"	""	"developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00612"	"4900"	"ENSG00000154146"	"NRGN"	"hsa:4900; Q92686"	""	"Long-term potentiation"	"1"	"0"	"3.8"	"2.0"	"2.0"	"5.7"	"3.0"	"4.3"	"5.4"	"17.1"	"12.1"	"36.4"	"30.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q969U7"	"Proteasome assembly chaperone 2 OS=Homo sapiens OX=9606 GN=PSMG2 PE=1 SV=1"	"0.000"	""	"3"	"1"	"1"	"1"	"264"	"29.4"	"6.98"	"265.13"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf09754"	"56984"	"ENSG00000128789"	"PSMG2"	"B0YJB3; hsa:56984; Q6IAH4; Q969U7; Q9NRV1; V9GYH7"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NHV4"	"Protein NEDD1 OS=Homo sapiens OX=9606 GN=NEDD1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"1"	"1"	"660"	"71.9"	"7.97"	"265.03"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf00400"	"121441"	"ENSG00000139350"	"NEDD1"	"B0AZN0; B4E145; G3V3F1; hsa:121441; Q8NA30; Q8NHV4"	""	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"7"	"0"	"96.6"	"75.5"	"84.4"	"76.9"	"81.1"	"73.7"	"104.8"	"134.7"	"133.0"	"231.2"	"283.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NYZ3"	"G2 and S phase-expressed protein 1 OS=Homo sapiens OX=9606 GN=GTSE1 PE=1 SV=3"	"0.000"	""	"3"	"1"	"1"	"1"	"720"	"76.6"	"9.39"	"263.04"	""	"1"	""	"cell cycle OR cell proliferation;stress response;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus"	"cytoskeletal activity"	"Pf15259"	"51512"	"ENSG00000075218"	"GTSE1"	"B0QYM3; hsa:51512; Q20WK2; Q53GX5; Q5R3I6; Q6DHX4; Q9BRE0; Q9NYZ3; Q9UGZ9; Q9Y557"	""	"G2/M Checkpoints; The role of GTSE1 in G2/M progression after G2 checkpoint"	"2"	"0"	"21.4"	"11.8"	"22.9"	"23.7"	"15.8"	"17.2"	"19.3"	"32.9"	"29.9"	"51.3"	"63.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BX10"	"GTP-binding protein 2 OS=Homo sapiens OX=9606 GN=GTPBP2 PE=1 SV=1"	"0.000"	""	"1"	"1"	"1"	"1"	"602"	"65.7"	"8.05"	"262.22"	""	"1"	""	"protein metabolism;other metabolic processes"	"non-structural extracellular;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009"	"54676"	"ENSG00000172432"	"GTPBP2"	"hsa:54676; Q5T7E8; Q8ND84; Q8TAH7; Q8WUA5; Q9BX10; Q9HCS9; Q9NRU4; Q9NX60"	"Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway"	"Platelet degranulation"	"2"	"0"	"16.1"	"12.2"	"12.9"	"14.2"	"10.1"	"21.6"	"22.0"	"34.2"	"29.9"	"46.0"	"62.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5TZA2"	"Rootletin OS=Homo sapiens OX=9606 GN=CROCC PE=1 SV=1"	"0.000"	""	"1"	"1"	"1"	"1"	"2017"	"228.4"	"5.50"	"262.16"	""	"1"	""	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"12.2"	"7.5"	"16.3"	"10.2"	"10.1"	"15.9"	"18.1"	"24.0"	"29.3"	"54.5"	"61.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q3SXY8"	"ADP-ribosylation factor-like protein 13B OS=Homo sapiens OX=9606 GN=ARL13B PE=1 SV=1"	"0.000"	""	"3"	"1"	"1"	"1"	"428"	"48.6"	"6.62"	"261.60"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00025"	"200894"	"ENSG00000169379"	"ARL13B"	"D3DN29; G3V1S8; hsa:200894; Q3SXY8; Q504W8; Q8TCL5"	"Genes related to primary cilium development (based on CRISPR); Joubert syndrome; Ciliopathies; Bardet-Biedl syndrome"	"Aggrephagy; RHOQ GTPase cycle; RHOJ GTPase cycle; Late endosomal microautophagy; ARL13B-mediated ciliary trafficking of INPP5E; Chaperone Mediated Autophagy"	"10"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NX07"	"tRNA selenocysteine 1-associated protein 1 OS=Homo sapiens OX=9606 GN=TRNAU1AP PE=1 SV=1"	"0.000"	""	"2"	"1"	"1"	"1"	"287"	"32.5"	"4.74"	"260.47"	""	"1"	""	"protein metabolism;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf17654"	"54952"	"ENSG00000180098"	"TRNAU1AP"	"hsa:54952; Q86SU7; Q9NX07"	""	""	"0"	"0"	"48.9"	"36.4"	"44.0"	"46.9"	"40.7"	"31.2"	"54.8"	"79.9"	"61.2"	"98.2"	"139.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P39656"	"Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4"	"0.000"	""	"2"	"1"	"1"	"1"	"456"	"50.8"	"6.55"	"260.38"	""	"1"	""	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity"	"Pf03345"	"1650"	"ENSG00000244038"	"DDOST"	"B2RDQ4; B4DJE3; B4DLI2; hsa:1650; O43244; P39656; Q5VWA5; Q8NI93; Q9BUI2"	"AGE/RAGE pathway; N-glycan biosynthesis"	"Neutrophil degranulation; SRP-dependent cotranslational protein targeting to membrane; Advanced glycosylation endproduct receptor signaling; Asparagine N-linked glycosylation; Maturation of spike protein"	"7"	"0"	"25.6"	"27.2"	"34.1"	"28.1"	"27.8"	"26.4"	"32.8"	"66.9"	"64.2"	"203.5"	"280.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P158"	"Putative ATP-dependent RNA helicase DHX57 OS=Homo sapiens OX=9606 GN=DHX57 PE=1 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"1386"	"155.5"	"7.71"	"259.60"	""	"1"	""	""	""	"other molecular function"	"Pf00270, Pf00271, Pf04408, Pf05773, Pf07717, Pf18044"	"90957"	"ENSG00000163214"	"DHX57"	"A2RRC7; hsa:90957; Q53SI4; Q6P158; Q6P9G1; Q7Z6H3; Q8NG17; Q96M33"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q709C8"	"Vacuolar protein sorting-associated protein 13C OS=Homo sapiens OX=9606 GN=VPS13C PE=1 SV=1"	"0.000"	""	"0"	"1"	"1"	"1"	"3753"	"422.1"	"6.83"	"259.09"	""	"1"	""	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf06650, Pf09333, Pf12624, Pf16908, Pf16909, Pf16910"	"54832"	"ENSG00000129003"	"VPS13C"	"hsa:54832; Q6ISR4; Q702P2; Q702P3; Q709C8; Q709C9; Q9NXN8; Q9P2C6"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51956"	"Serine/threonine-protein kinase Nek3 OS=Homo sapiens OX=9606 GN=NEK3 PE=1 SV=2"	"0.000"	""	"2"	"1"	"1"	"1"	"506"	"57.7"	"7.17"	"257.30"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"4752"	"ENSG00000136098"	"NEK3"	"A8K2J4; hsa:4752; P51956; Q5TAP2; Q8J023; Q8WUN5"	"Prolactin signaling pathway"	""	"1"	"0"	"5.7"	"8.2"	"7.3"	"6.8"	"5.2"	"5.9"	"6.8"	"9.6"	"12.2"	"29.0"	"33.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3D0"	"Cytosolic iron-sulfur assembly component 2B OS=Homo sapiens OX=9606 GN=CIAO2B PE=1 SV=1"	"0.000"	""	"4"	"1"	"1"	"1"	"163"	"17.7"	"5.19"	"256.61"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;cytoskeleton;nucleus;other cell component"	""	"Pf01883"	"51647"	"ENSG00000166595"	"CIAO2B"	"hsa:51647; Q9Y3D0"	"Iron-sulfur cluster biogenesis; 2q11.2 copy number variation syndrome"	"Cytosolic iron-sulfur cluster assembly"	"3"	"0"	"51.2"	"39.5"	"43.2"	"49.2"	"47.0"	"49.2"	"66.0"	"95.8"	"96.0"	"246.3"	"272.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75376"	"Nuclear receptor corepressor 1 OS=Homo sapiens OX=9606 GN=NCOR1 PE=1 SV=2"	"0.000"	""	"0"	"1"	"1"	"1"	"2440"	"270.0"	"7.11"	"255.35"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00249, Pf15784"	"9611"	"ENSG00000141027"	"NCOR1"	"B3DLF8; E9PGV6; hsa:9611; O75376; Q86YY0; Q9UPV5; Q9UQ18"	"Androgen receptor signaling pathway; Adipogenesis; Ovarian infertility; MECP2 and associated Rett syndrome; Pathways affected in adenoid cystic carcinoma; Rett syndrome causing genes; 22q11.2 copy number variation syndrome; Notch signaling pathway"	"HDACs deacetylate histones; PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; HCMV Early Events; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Heme signaling; Transcriptional activation of mitochondrial biogenesis; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Nuclear Receptor transcription pathway; Cytoprotection by HMOX1; Nuclear signaling by ERBB4; Downregulation of SMAD2/3:SMAD4 transcriptional activity; NR1D1 (REV-ERBA) represses gene expression; NOTCH1 Intracellular Domain Regulates Transcription; Notch-HLH transcription pathway; Loss of MECP2 binding ability to the NCoR/SMRT complex; Regulation of MECP2 expression and activity; NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux; NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis"	"30"	"0"	"69.3"	"55.2"	"68.1"	"59.9"	"57.4"	"57.5"	"81.2"	"138.2"	"110.0"	"259.8"	"334.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14181"	"DNA polymerase alpha subunit B OS=Homo sapiens OX=9606 GN=POLA2 PE=1 SV=2"	"0.000"	""	"2"	"1"	"1"	"1"	"598"	"65.9"	"5.24"	"255.22"	""	"1"	""	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;transport"	"cytosol;nucleus"	"nucleic acid binding activity"	"Pf04042, Pf08418"	"23649"	"ENSG00000014138"	"POLA2"	"B4DNB4; hsa:23649; Q14181; Q9BPV3"	"Pyrimidine metabolism; G1 to S cell cycle control; DNA replication"	"Defective pyroptosis; Activation of the pre-replicative complex; Inhibition of replication initiation of damaged DNA by RB1/E2F1; Polymerase switching on the C-strand of the telomere; Telomere C-strand synthesis initiation; DNA replication initiation; Polymerase switching; Removal of the Flap Intermediate"	"12"	"0"	"8.6"	"6.6"	"11.9"	"9.9"	"9.9"	"8.6"	"13.8"	"52.8"	"63.7"	"231.1"	"338.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5TKA1"	"Protein lin-9 homolog OS=Homo sapiens OX=9606 GN=LIN9 PE=1 SV=1"	"0.000"	""	"1"	"1"	"1"	"1"	"542"	"61.9"	"9.04"	"254.56"	""	"1"	""	"cell cycle OR cell proliferation;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf06584, Pf19438"	"286826"	"ENSG00000183814"	"LIN9"	"hsa:286826; Q5TKA1; Q5U5L8; Q5U7E1; Q6PI55; Q6ZTV4; Q7Z3J1"	"Gastric cancer network 1; DYRK1A involvement regarding cell proliferation in brain development"	"G1/S-Specific Transcription; Polo-like kinase mediated events; Cyclin E associated events during G1/S transition ; Transcription of E2F targets under negative control by DREAM complex; Cyclin A:Cdk2-associated events at S phase entry; Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"	"9"	"0"	"78.3"	"73.9"	"60.1"	"64.3"	"61.3"	"57.9"	"78.5"	"99.4"	"93.9"	"223.3"	"296.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NTM9"	"Copper homeostasis protein cutC homolog OS=Homo sapiens OX=9606 GN=CUTC PE=1 SV=1"	"0.000"	""	"2"	"1"	"1"	"1"	"273"	"29.3"	"8.18"	"252.55"	""	"1"	""	"cell organization and biogenesis;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf03932"	"51076"	"ENSG00000119929"	"CUTC"	"hsa:51076; Q5TCZ8; Q9NTM9; Q9Y321"	""	"Ion transport by P-type ATPases"	"1"	"0"	"148.1"	"117.6"	"113.6"	"117.6"	"130.8"	"135.2"	"151.7"	"222.8"	"202.4"	"298.0"	"342.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P0M9"	"39S ribosomal protein L27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL27 PE=1 SV=1"	"0.000"	""	"4"	"1"	"1"	"1"	"148"	"16.1"	"10.42"	"252.22"	""	"1"	""	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf01016"	"51264"	"ENSG00000108826"	"MRPL27"	"B2RE14; hsa:51264; Q9P0M9"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"78.2"	"81.1"	"69.3"	"62.8"	"75.4"	"59.5"	"85.6"	"161.3"	"124.2"	"371.9"	"766.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52735"	"Guanine nucleotide exchange factor VAV2 OS=Homo sapiens OX=9606 GN=VAV2 PE=1 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"878"	"101.2"	"7.08"	"252.14"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00017, Pf00130, Pf00169, Pf00307, Pf00621, Pf07653"	"7410"	"ENSG00000160293"	"VAV2"	"A2RUM4; A8MQ12; B6ZDF5; hsa:7410; P52735; Q5SYV3; Q5SYV4; Q5SYV5; Q6N012; Q6PIJ9; Q6Q317"	"Integrin-mediated cell adhesion; Prolactin signaling pathway; B cell receptor signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Focal adhesion; Hepatitis C and hepatocellular carcinoma; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Microglia pathogen phagocytosis pathway; Ebola virus infection in host; EGF/EGFR signaling pathway; 16p11.2 distal deletion syndrome; GDNF signaling"	"EPH-ephrin mediated repulsion of cells; Regulation of actin dynamics for phagocytic cup formation; FCERI mediated MAPK activation; FCERI mediated Ca+2 mobilization; FCGR3A-mediated phagocytosis; RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; NRAGE signals death through JNK; G alpha (12/13) signalling events; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOB GTPase cycle; GPVI-mediated activation cascade; DAP12 signaling; Signal transduction by L1; Azathioprine ADME; VEGFR2 mediated vascular permeability"	"34"	"0"	"0.0"	"0.0"	"3.3"	"0.0"	"2.5"	"3.1"	"3.1"	"48.5"	"57.0"	"301.9"	"434.7"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6BDS2"	"UHRF1-binding protein 1 OS=Homo sapiens OX=9606 GN=UHRF1BP1 PE=1 SV=1"	"0.000"	""	"0"	"1"	"1"	"1"	"1440"	"159.4"	"6.14"	"250.27"	""	"1"	""	""	"other cytoplasmic organelle"	"other molecular function"	"Pf12624"	"54887"	"ENSG00000065060"	"BLTP3A"	"hsa:54887; Q6BDS2; Q9NXE0"	""	""	"0"	"0"	"47.6"	"41.3"	"44.8"	"41.5"	"40.4"	"43.0"	"56.4"	"66.4"	"68.3"	"110.0"	"134.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z3J2"	"VPS35 endosomal protein sorting factor-like OS=Homo sapiens OX=9606 GN=VPS35L PE=1 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"963"	"109.5"	"7.21"	"250.00"	""	"1"	""	"transport"	"plasma membrane;other membranes;other cytoplasmic organelle"	""	""	"57020"	"ENSG00000103544"	"VPS35L"	"A8K2M1; hsa:57020; O43329; Q69YI1; Q6PDA0; Q7L371; Q7Z3J2; Q86W66; Q8WXA5; Q9H0L7; Q9H7C8"	""	"Neutrophil degranulation"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13464"	"Rho-associated protein kinase 1 OS=Homo sapiens OX=9606 GN=ROCK1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"1"	"1"	"1354"	"158.1"	"5.90"	"249.97"	""	"1"	""	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"enzyme regulator activity;cytoskeletal activity;kinase activity;other molecular function"	"Pf00069, Pf08912"	"6093"	"ENSG00000067900"	"ROCK1"	"B0YJ91; hsa:6093; Q13464; Q2KHM4; Q59GZ4"	"Androgen receptor signaling pathway; MicroRNAs in cardiomyocyte hypertrophy; Integrin-mediated cell adhesion; Leptin signaling pathway; Microtubule cytoskeleton regulation; Pathogenic Escherichia coli infection; AGE/RAGE pathway; Focal adhesion; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; EGF/EGFR signaling pathway; Gastrin signaling pathway; mBDNF and proBDNF regulation of GABA neurotransmission; MAP3K1 role in promoting and blocking gonadal determination; Airway smooth muscle cell contraction; RAS and bradykinin pathways in COVID-19; Regulation of actin cytoskeleton; GDNF signaling; G13 signaling pathway"	"Potential therapeutics for SARS; Neutrophil degranulation; G alpha (12/13) signalling events; EPHB-mediated forward signaling; RHOC GTPase cycle; RHOA GTPase cycle; RHOB GTPase cycle; VEGFA-VEGFR2 Pathway; RND3 GTPase cycle; EPHA-mediated growth cone collapse; Sema4D induced cell migration and growth-cone collapse; RHO GTPases Activate ROCKs; RHOBTB1 GTPase cycle; RHOH GTPase cycle; Apoptotic cleavage of cellular proteins"	"34"	"0"	"3.4"	"8.8"	"5.4"	"3.8"	"5.0"	"3.5"	"6.6"	"21.5"	"22.2"	"94.6"	"283.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UJC3"	"Protein Hook homolog 1 OS=Homo sapiens OX=9606 GN=HOOK1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"728"	"84.6"	"5.15"	"249.94"	""	"1"	""	"cell organization and biogenesis;transport;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf05622, Pf19047"	"51361"	"ENSG00000134709"	"HOOK1"	"A8K8E9; A8MU44; B4DX15; hsa:51361; O60561; Q5TG44; Q9UJC3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50995"	"Annexin A11 OS=Homo sapiens OX=9606 GN=ANXA11 PE=1 SV=1"	"0.000"	""	"2"	"1"	"1"	"1"	"505"	"54.4"	"7.65"	"249.04"	""	"1"	""	"cell cycle OR cell proliferation;transport;other biological processes"	"cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00191"	"311"	"ENSG00000122359"	"ANXA11"	"B4DVE7; hsa:311; P50995"	""	""	"0"	"0"	"80.3"	"65.7"	"86.7"	"87.7"	"82.6"	"65.9"	"95.5"	"162.1"	"157.7"	"324.4"	"462.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UPU5"	"Ubiquitin carboxyl-terminal hydrolase 24 OS=Homo sapiens OX=9606 GN=USP24 PE=1 SV=3"	"0.000"	""	"0"	"1"	"1"	"1"	"2620"	"294.2"	"6.14"	"248.23"	""	"1"	""	"protein metabolism;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf00443, Pf12030"	"23358"	"ENSG00000162402"	"USP24"	"hsa:23358; Q6ZSY2; Q8N2Y4; Q9NXD1; Q9UPU5"	""	"Ub-specific processing proteases"	"1"	"0"	"23.2"	"22.7"	"22.0"	"20.4"	"16.9"	"19.5"	"30.2"	"42.3"	"41.3"	"165.3"	"309.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NRW7"	"Vacuolar protein sorting-associated protein 45 OS=Homo sapiens OX=9606 GN=VPS45 PE=1 SV=1"	"0.000"	""	"2"	"1"	"1"	"1"	"570"	"65.0"	"8.24"	"246.08"	""	"1"	""	"transport"	"other membranes;ER/Golgi;other cytoplasmic organelle"	""	"Pf00995"	"11311"	"ENSG00000136631"	"VPS45"	"D3DUZ9; F5H8K1; hsa:11311; Q15715; Q53FR8; Q5T4P6; Q9NRW7; Q9Y4Z6"	""	"Factors involved in megakaryocyte development and platelet production; Intra-Golgi traffic; SARS-CoV-2 modulates autophagy"	"3"	"0"	"7.6"	"4.9"	"4.9"	"7.1"	"5.2"	"3.3"	"6.0"	"10.5"	"14.8"	"34.9"	"51.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2P8"	"RNA 3'-terminal phosphate cyclase-like protein OS=Homo sapiens OX=9606 GN=RCL1 PE=1 SV=3"	"0.000"	""	"3"	"1"	"1"	"1"	"373"	"40.8"	"9.26"	"245.69"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf01137, Pf05189"	"10171"	"ENSG00000120158"	"RCL1"	"D3DRI2; hsa:10171; Q5VYW9; Q5VZU1; Q9H9D0; Q9NY00; Q9P044; Q9Y2P8"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"11.8"	"12.0"	"12.9"	"11.1"	"12.0"	"8.1"	"15.6"	"23.9"	"17.7"	"42.9"	"62.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P54764"	"Ephrin type-A receptor 4 OS=Homo sapiens OX=9606 GN=EPHA4 PE=1 SV=1"	"0.000"	""	"1"	"1"	"1"	"1"	"986"	"109.8"	"6.61"	"244.70"	""	"1"	""	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;kinase activity;other molecular function"	"Pf00041, Pf01404, Pf07647, Pf07714, Pf14575"	"2043"	"ENSG00000116106"	"EPHA4"	"A8K2P1; B2R601; B7Z6Q8; hsa:2043; P54764; Q2M380"	"Spinal cord injury; Gene regulatory network modelling somitogenesis ; Fragile X syndrome; Somitogenesis in the context of spondylocostal dysostosis"	"Somitogenesis; EPH-ephrin mediated repulsion of cells; EPHA-mediated growth cone collapse"	"8"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8ND82"	"Zinc finger protein 280C OS=Homo sapiens OX=9606 GN=ZNF280C PE=1 SV=1"	"0.000"	""	"1"	"1"	"1"	"1"	"737"	"83.0"	"9.11"	"243.81"	""	"1"	""	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf13836"	"55609"	"ENSG00000056277"	"ZNF280C"	"A8K2V8; hsa:55609; Q8ND82; Q9NXR3"	""	""	"0"	"0"	"29.0"	"22.5"	"25.5"	"32.3"	"26.9"	"22.5"	"29.5"	"42.3"	"37.0"	"49.3"	"86.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95490"	"Adhesion G protein-coupled receptor L2 OS=Homo sapiens OX=9606 GN=ADGRL2 PE=1 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"1459"	"163.2"	"6.43"	"243.77"	""	"1"	""	"developmental processes;signal transduction"	"other membranes;other cell component"	"other molecular function"	"Pf00002, Pf01825, Pf02140, Pf02191, Pf02354, Pf02793, Pf16489"	"23266"	"ENSG00000117114"	"ADGRL2"	"A5XEI2; B1ALT8; B1ALT9; B1ALU0; B1ALU2; B1ALU4; B1ALU5; B1ALU6; hsa:23266; O94882; O95490; Q5VX76; Q9UKY5; Q9UKY6"	"GPCRs, other; GPCRs, class B secretin-like"	""	"2"	"0"	"0.0"	"0.0"	"5.1"	"0.0"	"2.3"	"0.0"	"4.0"	"9.8"	"18.6"	"48.6"	"61.0"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WVX9"	"Fatty acyl-CoA reductase 1 OS=Homo sapiens OX=9606 GN=FAR1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"1"	"1"	"515"	"59.3"	"9.17"	"240.68"	""	"1"	""	"other metabolic processes"	"other membranes;other cytoplasmic organelle"	"other molecular function"	"Pf03015, Pf07993"	"84188"	"ENSG00000197601"	"FAR1"	"D3DQW8; hsa:84188; Q5CZA3; Q8WVX9"	""	"Wax biosynthesis"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVE5"	"Ubiquitin carboxyl-terminal hydrolase 40 OS=Homo sapiens OX=9606 GN=USP40 PE=1 SV=3"	"0.000"	""	"1"	"1"	"1"	"1"	"1235"	"140.0"	"5.67"	"240.23"	""	"1"	""	"protein metabolism;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf00443"	"55230"	"ENSG00000085982"	"USP40"	"hsa:55230; Q6NX38; Q70EL0; Q9NVE5"	"2q37 copy number variation syndrome"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13111"	"Chromatin assembly factor 1 subunit A OS=Homo sapiens OX=9606 GN=CHAF1A PE=1 SV=3"	"0.000"	""	"1"	"1"	"1"	"1"	"956"	"106.8"	"5.94"	"239.85"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf11600, Pf12253, Pf15539, Pf15557"	"10036"	"ENSG00000167670"	"CHAF1A"	"hsa:10036; Q13111; Q6NXG5; Q7Z7K3; Q9UJY8"	"Nanoparticle triggered autophagic cell death"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NZC9"	"SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 OS=Homo sapiens OX=9606 GN=SMARCAL1 PE=1 SV=1"	"0.001"	""	"1"	"1"	"1"	"1"	"954"	"105.9"	"9.06"	"236.78"	""	"1"	""	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf07443"	"50485"	"ENSG00000138375"	"SMARCAL1"	"A6NEH0; hsa:50485; Q53R00; Q96AY1; Q9NXQ5; Q9NZC9; Q9UFH3; Q9UI93"	"Primary focal segmental glomerulosclerosis (FSGS); Nephrotic syndrome"	""	"2"	"0"	"16.2"	"9.9"	"16.0"	"14.1"	"9.8"	"15.5"	"18.1"	"23.8"	"24.4"	"42.3"	"61.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P82909"	"28S ribosomal protein S36, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS36 PE=1 SV=2"	"0.001"	""	"12"	"1"	"1"	"1"	"103"	"11.5"	"9.99"	"236.11"	""	"1"	""	"other metabolic processes"	"other membranes;mitochondrion"	""	""	"92259"	"ENSG00000134056; ENSG00000278461"	"MRPS36"	"hsa:92259; P82909; Q9H2H4"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"39.6"	"23.7"	"33.0"	"35.0"	"32.7"	"29.4"	"46.3"	"110.7"	"104.8"	"334.7"	"426.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y620"	"DNA repair and recombination protein RAD54B OS=Homo sapiens OX=9606 GN=RAD54B PE=1 SV=1"	"0.001"	""	"1"	"1"	"1"	"1"	"910"	"102.9"	"8.12"	"235.94"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271"	"25788"	"ENSG00000197275"	"RAD54B"	"F6WBS8; hsa:25788; Q9Y620"	"Homologous recombination; DNA repair pathways, full network"	""	"2"	"0"	"17.5"	"18.9"	"21.3"	"21.1"	"18.4"	"19.6"	"23.6"	"39.2"	"39.8"	"63.6"	"53.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P98082"	"Disabled homolog 2 OS=Homo sapiens OX=9606 GN=DAB2 PE=1 SV=3"	"0.001"	""	"2"	"1"	"1"	"1"	"770"	"82.4"	"5.53"	"235.85"	""	"1"	""	"cell-cell signaling;cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00640"	"1601"	"ENSG00000153071"	"DAB2"	"A6NES5; hsa:1601; P98082; Q13598; Q9BTY0; Q9UK04"	"Endoderm differentiation"	"Cargo recognition for clathrin-mediated endocytosis; Formation of annular gap junctions"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H3P7"	"Golgi resident protein GCP60 OS=Homo sapiens OX=9606 GN=ACBD3 PE=1 SV=4"	"0.001"	""	"1"	"1"	"1"	"1"	"528"	"60.6"	"5.06"	"235.18"	""	"1"	""	"other metabolic processes"	"other membranes;mitochondrion;ER/Golgi"	"other molecular function"	"Pf00887, Pf13897"	"64746"	"ENSG00000182827"	"ACBD3"	"B2RB29; hsa:64746; Q5VTJ0; Q6P9F1; Q8IZC5; Q8N4D6; Q9H3P7; Q9H6U3"	""	"Golgi Associated Vesicle Biogenesis"	"1"	"0"	"57.8"	"45.4"	"41.1"	"41.2"	"33.0"	"42.0"	"63.2"	"105.0"	"98.8"	"179.5"	"246.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5A9"	"YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2"	"0.001"	""	"1"	"1"	"1"	"1"	"579"	"62.3"	"8.79"	"234.00"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity"	"Pf04146"	"51441"	"ENSG00000198492"	"YTHDF2"	"A6NKG4; A8K966; B4E1G7; D3DPM8; hsa:51441; Q5VSZ9; Q8TDH0; Q9BUJ5; Q9Y5A9"	""	""	"0"	"0"	"61.4"	"71.2"	"52.7"	"54.0"	"56.0"	"55.9"	"68.0"	"111.6"	"109.6"	"224.5"	"330.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P04183"	"Thymidine kinase, cytosolic OS=Homo sapiens OX=9606 GN=TK1 PE=1 SV=2"	"0.001"	""	"8"	"1"	"1"	"1"	"234"	"25.5"	"8.51"	"233.69"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes"	"cytosol;nucleus"	"kinase activity;other molecular function"	"Pf00265"	"7083"	"ENSG00000167900"	"TK1"	"B2RC58; hsa:7083; P04183; Q969V0; Q9UMG9"	"Fluoropyrimidine activity; Pyrimidine metabolism"	"Pyrimidine salvage; G1/S-Specific Transcription"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35613"	"Basigin OS=Homo sapiens OX=9606 GN=BSG PE=1 SV=2"	"0.001"	""	"2"	"1"	"1"	"1"	"385"	"42.2"	"5.66"	"233.23"	""	"1"	""	"developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf13927"	"682"	"ENSG00000172270"	"BSG"	"A6NJW1; D3YLG5; hsa:682; P35613; Q7Z796; Q8IZL7"	"Matrix metalloproteinases; VEGFA-VEGFR2 signaling; IL-18 signaling pathway"	"Degradation of the extracellular matrix; Integrin cell surface interactions; Pyruvate metabolism; Aspirin ADME; Basigin interactions; Proton-coupled monocarboxylate transport; Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT)"	"10"	"0"	"238.3"	"227.3"	"247.1"	"243.7"	"213.6"	"192.2"	"239.8"	"452.1"	"392.4"	"872.8"	"1091.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6G3"	"39S ribosomal protein L42, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL42 PE=1 SV=1"	"0.001"	""	"4"	"1"	"1"	"1"	"142"	"16.7"	"8.35"	"233.20"	""	"1"	""	"protein metabolism;other metabolic processes"	"plasma membrane;other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf10210"	"28977"	"ENSG00000198015"	"MRPL42"	"hsa:28977; Q6FID1; Q96Q48; Q9P0S1; Q9Y6G3"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"36.8"	"33.1"	"43.6"	"35.3"	"33.4"	"28.5"	"42.6"	"75.1"	"53.3"	"135.7"	"156.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H6Y2"	"WD repeat-containing protein 55 OS=Homo sapiens OX=9606 GN=WDR55 PE=1 SV=2"	"0.001"	""	"2"	"1"	"1"	"1"	"383"	"42.0"	"4.92"	"233.08"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf00400, Pf12894"	"54853"	"ENSG00000120314"	"WDR55"	"hsa:54853; Q9H6Y2; Q9NXK4"	""	""	"0"	"0"	"74.5"	"54.9"	"60.6"	"67.8"	"51.7"	"57.7"	"82.0"	"124.2"	"123.3"	"257.4"	"364.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15746"	"Myosin light chain kinase, smooth muscle OS=Homo sapiens OX=9606 GN=MYLK PE=1 SV=4"	"0.001"	""	"0"	"1"	"1"	"1"	"1914"	"210.6"	"6.15"	"232.97"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;kinase activity;other molecular function"	"Pf00041, Pf00069, Pf07679, Pf16620"	"4638"	"ENSG00000065534"	"MYLK"	"B4DUE3; D3DN97; hsa:4638; O95796; O95797; O95798; O95799; Q14844; Q15746; Q16794; Q17S15; Q3ZCP9; Q5MY99; Q5MYA0; Q6P2N0; Q7Z4J0; Q9C0L5; Q9UBG5; Q9UBY6; Q9UIT9"	"MicroRNAs in cardiomyocyte hypertrophy; Endothelin pathways; Focal adhesion; Physico-chemical features and toxicity-associated pathways; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Airway smooth muscle cell contraction; Regulation of actin cytoskeleton"	"RHO GTPases activate PAKs; Smooth Muscle Contraction"	"9"	"0"	"8.9"	"4.0"	"5.7"	"4.8"	"6.8"	"5.6"	"6.3"	"10.8"	"16.4"	"20.1"	"34.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBC2"	"Epidermal growth factor receptor substrate 15-like 1 OS=Homo sapiens OX=9606 GN=EPS15L1 PE=1 SV=1"	"0.001"	""	"1"	"1"	"1"	"1"	"864"	"94.2"	"5.11"	"232.10"	""	"1"	""	"transport"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf12763"	"58513"	"ENSG00000127527"	"EPS15L1"	"A2RRF3; A5PL29; B4DKA3; hsa:58513; Q9UBC2"	"EGF/EGFR signaling pathway"	"Cargo recognition for clathrin-mediated endocytosis; EGFR downregulation"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6M9"	"NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 OS=Homo sapiens OX=9606 GN=NDUFB9 PE=1 SV=3"	"0.001"	""	"3"	"1"	"1"	"1"	"179"	"21.8"	"8.38"	"231.26"	""	"1"	""	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity"	"Pf05347"	"4715"	"ENSG00000147684"	"NDUFB9"	"B2R8M6; hsa:4715; Q9UQE8; Q9Y6M9"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial immune response to SARS-CoV-2; Oxidative phosphorylation"	"Complex I biogenesis"	"6"	"0"	"63.8"	"49.2"	"54.4"	"60.8"	"50.8"	"52.7"	"66.5"	"209.8"	"208.6"	"477.8"	"683.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43709"	"Probable 18S rRNA (guanine-N(7))-methyltransferase OS=Homo sapiens OX=9606 GN=BUD23 PE=1 SV=2"	"0.001"	""	"2"	"1"	"1"	"1"	"281"	"31.9"	"8.73"	"230.98"	""	"1"	""	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf08241, Pf12589"	"114049"	"ENSG00000071462"	"BUD23"	"A8K501; C9K060; hsa:114049; O43709; Q96P12; Q9BQ58; Q9HBP9"	"7q11.23 copy number variation syndrome"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"3"	"0"	"91.1"	"75.4"	"83.1"	"88.6"	"85.8"	"87.0"	"116.5"	"208.2"	"185.7"	"312.8"	"295.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""