"Checked"	"Master"	"Accession"	"Description"	"Coverage [%]"	"# Peptides"	"# PSMs"	"# Unique Peptides"	"# AAs"	"MW [kDa]"	"calc. pI"	"Score MS Amanda 2.0: MS Amanda 2.0"	"Score Sequest HT: Sequest HT"	"# Peptides (by Search Engine): MS Amanda 2.0"	"# Peptides (by Search Engine): Sequest HT"	"Biological Process"	"Cellular Component"	"Molecular Function"	"Pfam IDs"	"Entrez Gene ID"	"Ensembl Gene ID"	"Gene Symbol"	"Gene ID"	"WikiPathways"	"Reactome Pathways"	"# Protein Pathway Groups"	"# Razor Peptides"	"Abundances (Grouped): 126"	"Abundances (Grouped): 127N"	"Abundances (Grouped): 127C"	"Abundances (Grouped): 128N"	"Abundances (Grouped): 128C"	"Abundances (Grouped): 129N"	"Abundances (Grouped): 129C"	"Abundances (Grouped): 130N"	"Abundances (Grouped): 130C"	"Abundances (Grouped): 131N"	"Abundances (Grouped): 131C"	"Abundances (Grouped) CV [%]: 126"	"Abundances (Grouped) CV [%]: 127N"	"Abundances (Grouped) CV [%]: 127C"	"Abundances (Grouped) CV [%]: 128N"	"Abundances (Grouped) CV [%]: 128C"	"Abundances (Grouped) CV [%]: 129N"	"Abundances (Grouped) CV [%]: 129C"	"Abundances (Grouped) CV [%]: 130N"	"Abundances (Grouped) CV [%]: 130C"	"Abundances (Grouped) CV [%]: 131N"	"Abundances (Grouped) CV [%]: 131C"	"Found in Sample: F9: 126, Sample"	"Found in Sample: F9: 127N, Sample"	"Found in Sample: F9: 127C, Sample"	"Found in Sample: F9: 128N, Sample"	"Found in Sample: F9: 128C, Sample"	"Found in Sample: F9: 129N, Sample"	"Found in Sample: F9: 129C, Sample"	"Found in Sample: F9: 130N, Sample"	"Found in Sample: F9: 130C, Sample"	"Found in Sample: F9: 131N, Sample"	"Found in Sample: F9: 131C, Sample"	"# Protein Groups"	"Modifications"
"False"	"IsMasterProtein"	"Q13813"	"Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3"	"60"	"150"	"371"	"150"	"2472"	"284.4"	"5.35"	"73044.82"	"836.94"	"120"	"136"	"cell organization and biogenesis"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00018, Pf00435, Pf08726, Pf13499"	"6709"	"ENSG00000197694"	"SPTAN1"	"hsa:6709; Q13186; Q13813; Q15324; Q16606; Q59EF1; Q5VXV5; Q5VXV6; Q7Z6M5; Q9P0V0"	"Fas ligand pathway and stress induction of heat shock proteins"	"Neutrophil degranulation; RHOV GTPase cycle; COPI-mediated anterograde transport; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; RHOU GTPase cycle; Nephrin family interactions; RAF/MAP kinase cascade; NCAM signaling for neurite out-growth; Interaction between L1 and Ankyrins; Caspase-mediated cleavage of cytoskeletal proteins"	"12"	"0"	"5222.6"	"4984.9"	"5970.9"	"4878.4"	"5760.4"	"5731.9"	"7000.4"	"10391.2"	"91222.6"	"109869.1"	"132557.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01082"	"Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2"	"52"	"115"	"281"	"102"	"2364"	"274.4"	"5.57"	"60777.16"	"557.00"	"103"	"105"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00169, Pf00307, Pf00435"	"6711"	"ENSG00000115306"	"SPTBN1"	"B2RP63; hsa:6711; O60837; Q01082; Q16057; Q53R99; Q59ER3; Q8IX99"	"Sudden infant death syndrome (SIDS) susceptibility pathways"	"RHOV GTPase cycle; RHOU GTPase cycle; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; COPI-mediated anterograde transport; Nephrin family interactions; RAF/MAP kinase cascade; NCAM signaling for neurite out-growth; Interaction between L1 and Ankyrins; Signaling by FLT3 fusion proteins"	"11"	"14"	"3121.1"	"2987.5"	"3767.0"	"3074.3"	"3643.6"	"3647.2"	"4417.9"	"6291.9"	"55733.7"	"73838.2"	"88526.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P20700"	"Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2"	"75"	"62"	"203"	"54"	"586"	"66.4"	"5.16"	"36631.16"	"421.37"	"53"	"57"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytoskeleton;nucleus"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00038, Pf00932"	"4001"	"ENSG00000113368"	"LMNB1"	"B2R6J6; hsa:4001; P20700; Q3SYN7; Q96EI6"	"Fas ligand pathway and stress induction of heat shock proteins; Familial partial lipodystrophy; Progeria-associated lipodystrophy; Acquired partial lipodystrophy / Barraquer-Simons syndrome"	"Meiotic synapsis; RHOD GTPase cycle; RHOF GTPase cycle; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models; Initiation of Nuclear Envelope (NE) Reformation; Depolymerization of the Nuclear Lamina; Breakdown of the nuclear lamina; Formation of Senescence-Associated Heterochromatin Foci (SAHF)"	"14"	"9"	"8637.5"	"9217.4"	"8904.7"	"7690.5"	"8472.0"	"8499.7"	"10343.0"	"12841.5"	"22139.7"	"36075.7"	"49025.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WXH0"	"Nesprin-2 OS=Homo sapiens OX=9606 GN=SYNE2 PE=1 SV=3"	"17"	"98"	"181"	"97"	"6885"	"795.9"	"5.36"	"33416.07"	"335.19"	"84"	"88"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00435, Pf10541"	"23224"	"ENSG00000054654"	"SYNE2"	"B4DND7; B4DPR6; hsa:23224; I6XXQ5; Q540G1; Q86YP9; Q8N1S3; Q8NF49; Q8TER7; Q8WWW3; Q8WWW4; Q8WWW5; Q8WXH0; Q8WXH1; Q9NU50; Q9UFQ4; Q9Y2L4; Q9Y4R1"	"Ovarian infertility; Rett syndrome causing genes; Envelope proteins and their potential roles in EDMD physiopathology"	"Meiotic synapsis"	"4"	"1"	"2199.8"	"1904.7"	"2590.2"	"2155.4"	"2468.8"	"2519.9"	"2976.2"	"5408.7"	"20524.8"	"42391.2"	"54264.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P12270"	"Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3"	"32"	"71"	"147"	"71"	"2363"	"267.1"	"5.02"	"31171.69"	"275.31"	"64"	"65"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"other membranes;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf07926"	"7175"	"ENSG00000047410"	"TPR"	"hsa:7175; P12270; Q15624; Q15655; Q5SWY0; Q99968"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; HCMV Late Events; HCMV Early Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Signaling by ALK fusions and activated point mutants"	"29"	"0"	"5950.8"	"5486.6"	"5932.2"	"4851.2"	"5892.8"	"6298.5"	"7147.8"	"8767.3"	"15983.3"	"33744.7"	"57238.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13639"	"Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4"	"49"	"48"	"124"	"47"	"858"	"95.3"	"6.83"	"23689.08"	"264.11"	"37"	"43"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00009, Pf00679, Pf03144, Pf03764, Pf14492"	"1938"	"ENSG00000167658"	"EEF2"	"A0A384N6H1; B2RMP5; D6W618; hsa:1938; P13639; Q58J86"	"Translation factors; AMP-activated protein kinase signaling; Brain-derived neurotrophic factor (BDNF) signaling pathway; IL-18 signaling pathway"	"Neutrophil degranulation; Protein methylation; Uptake and function of diphtheria toxin; Peptide chain elongation; Synthesis of diphthamide-EEF2"	"9"	"1"	"1210.2"	"1247.0"	"1459.6"	"1235.6"	"1458.3"	"1424.2"	"1756.8"	"2928.1"	"15674.1"	"36746.6"	"55588.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22626"	"Heterogeneous nuclear ribonucleoproteins A2/B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2"	"68"	"27"	"102"	"24"	"353"	"37.4"	"8.95"	"17040.48"	"247.46"	"21"	"25"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"3181"	"ENSG00000122566"	"HNRNPA2B1"	"A0A024RA27; A0A024RA61; A8K064; hsa:3181; P22626; P22627; Q9UC98; Q9UDJ2"	"mRNA processing"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"4"	"3"	"9472.0"	"9579.2"	"9058.7"	"8223.6"	"9278.2"	"8662.2"	"10777.8"	"12597.0"	"13696.6"	"18767.9"	"27790.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14683"	"Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2"	"48"	"61"	"130"	"61"	"1233"	"143.1"	"7.64"	"22229.77"	"229.42"	"52"	"55"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02463, Pf06470"	"8243"	"ENSG00000072501"	"SMC1A"	"hsa:8243; O14995; Q14683; Q16351; Q2M228"	"miRNA regulation of DNA damage response; Cell cycle; Retinoblastoma gene in cancer; Constitutive androstane receptor pathway; Nuclear receptors meta-pathway; Pathways affected in adenoid cystic carcinoma; ATM signaling in development and disease ; mRNA processing; Regulation of sister chromatid separation at the metaphase-anaphase transition; Rett syndrome causing genes; CAMKK2 pathway; Cohesin complex - Cornelia de Lange syndrome; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; 10q22q23 copy number variation; DNA damage response"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Estrogen-dependent gene expression; Meiotic synapsis; SUMOylation of DNA damage response and repair proteins; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"22"	"0"	"5237.7"	"4630.3"	"5462.7"	"4689.2"	"5499.0"	"5590.7"	"6572.1"	"7835.0"	"15892.5"	"29020.7"	"37397.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q03252"	"Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4"	"60"	"52"	"130"	"43"	"620"	"69.9"	"5.59"	"23766.74"	"227.91"	"48"	"50"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytoskeleton;nucleus"	"cytoskeletal activity;other molecular function"	"Pf00038, Pf00932"	"84823"	"ENSG00000176619"	"LMNB2"	"hsa:84823; O75292; Q03252; Q14734; Q96DF6"	"Gastric cancer network 2; Fas ligand pathway and stress induction of heat shock proteins; IL-18 signaling pathway; Familial partial lipodystrophy; Progeria-associated lipodystrophy; Acquired partial lipodystrophy / Barraquer-Simons syndrome"	""	"6"	"1"	"5008.4"	"5139.7"	"5369.0"	"4682.3"	"5098.7"	"5164.6"	"6093.6"	"7716.5"	"12752.8"	"22169.3"	"30481.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P02545"	"Prelamin-A/C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1"	"52"	"49"	"122"	"47"	"664"	"74.1"	"7.02"	"23299.80"	"220.03"	"46"	"46"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00038, Pf00932"	"4000"	"ENSG00000160789"	"LMNA"	"B4DI32; D3DVB0; D6RAQ3; E7EUI9; hsa:4000; P02545; P02546; Q5I6Y4; Q5I6Y6; Q5TCJ2; Q5TCJ3; Q6UYC3; Q969I8; Q96JA2"	"Arrhythmogenic right ventricular cardiomyopathy; Adipogenesis; Fas ligand pathway and stress induction of heat shock proteins; Lamin A-processing pathway; Nephrotic syndrome; Influence of laminopathies on Wnt signaling; Overlap between signal transduction pathways contributing to LMNA laminopathies; Familial partial lipodystrophy; Progeria-associated lipodystrophy; Acquired partial lipodystrophy / Barraquer-Simons syndrome; Primary ovarian insufficiency"	"XBP1(S) activates chaperone genes; Signaling by BRAF and RAF1 fusions"	"13"	"0"	"5676.4"	"5798.5"	"5951.1"	"4900.8"	"5578.0"	"6280.6"	"7321.0"	"9454.7"	"18296.8"	"28797.0"	"34507.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08670"	"Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4"	"69"	"42"	"111"	"38"	"466"	"53.6"	"5.12"	"23187.78"	"200.06"	"36"	"37"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00038, Pf04732"	"7431"	"ENSG00000026025"	"VIM"	"B0YJC2; D3DRU4; hsa:7431; P08670; Q15867; Q15868; Q15869; Q548L2; Q6LER9; Q8N850; Q96ML2; Q9NTM3"	"Allograft rejection; Spinal cord injury; Primary focal segmental glomerulosclerosis (FSGS); Mammary gland development pathway - Puberty (Stage 2 of 4); Apoptosis-related network due to altered Notch3 in ovarian cancer; Striated muscle contraction pathway; TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition; Ciliary landscape; Burn wound healing; CCL18 signaling pathway; TROP2 regulatory signaling; CKAP4 signaling pathway map; A network map of Macrophage-stimulating protein (MSP) signaling; T-cell receptor signaling pathway"	"Aggrephagy; Interleukin-4 and Interleukin-13 signaling; Chaperone Mediated Autophagy; Late endosomal microautophagy; Striated Muscle Contraction; RHOBTB1 GTPase cycle; Caspase-mediated cleavage of cytoskeletal proteins"	"21"	"5"	"4543.7"	"4822.6"	"4650.2"	"3102.9"	"4129.7"	"4162.2"	"5424.5"	"7132.1"	"11461.1"	"16560.5"	"23449.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15020"	"Spectrin beta chain, non-erythrocytic 2 OS=Homo sapiens OX=9606 GN=SPTBN2 PE=1 SV=3"	"25"	"51"	"109"	"41"	"2390"	"271.2"	"6.11"	"23968.87"	"197.50"	"47"	"42"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00435, Pf15410"	"6712"	"ENSG00000173898"	"SPTBN2"	"hsa:6712; O14872; O14873; O15020"	""	"MHC class II antigen presentation; COPI-mediated anterograde transport; RAF/MAP kinase cascade; NCAM signaling for neurite out-growth; Interaction between L1 and Ankyrins"	"5"	"0"	"1129.0"	"1042.0"	"1282.7"	"1049.1"	"1269.8"	"1312.8"	"1532.7"	"2297.5"	"10995.7"	"21661.2"	"27211.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08133"	"Annexin A6 OS=Homo sapiens OX=9606 GN=ANXA6 PE=1 SV=3"	"54"	"33"	"83"	"33"	"673"	"75.8"	"5.60"	"12288.74"	"191.03"	"18"	"32"	"cell organization and biogenesis;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;mitochondrion;other cytoplasmic organelle;other cell component"	"transporter activity;cytoskeletal activity;other molecular function"	"Pf00191"	"309"	"ENSG00000197043"	"ANXA6"	"B7Z8A7; D3DQH4; E9PGK1; hsa:309; P08133; Q6ZT79"	"Calcium regulation in cardiac cells; Prostaglandin synthesis and regulation"	"Smooth Muscle Contraction"	"3"	"0"	"687.2"	"586.3"	"855.0"	"707.2"	"818.8"	"758.2"	"956.2"	"1123.3"	"3137.4"	"21920.0"	"64738.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UQE7"	"Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2"	"40"	"50"	"109"	"49"	"1217"	"141.5"	"7.18"	"21231.62"	"190.83"	"45"	"47"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf02463, Pf06470"	"9126"	"ENSG00000108055"	"SMC3"	"A8K156; hsa:9126; O60464; Q5T482; Q9UQE7"	"Cell cycle; Retinoblastoma gene in cancer; MECP2 and associated Rett syndrome; Prion disease pathway; Regulation of sister chromatid separation at the metaphase-anaphase transition; Cohesin complex - Cornelia de Lange syndrome; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; 10q22q23 copy number variation"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; SUMOylation of DNA damage response and repair proteins; Meiotic synapsis; Estrogen-dependent gene expression; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"15"	"1"	"4733.5"	"4149.4"	"4600.6"	"4117.8"	"4722.4"	"4984.7"	"5709.3"	"6886.1"	"14181.0"	"26593.2"	"33821.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q00839"	"Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6"	"44"	"36"	"94"	"35"	"825"	"90.5"	"6.00"	"18167.86"	"178.76"	"23"	"30"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00622, Pf02037, Pf13671"	"3192"	"ENSG00000153187"	"HNRNPU"	"hsa:3192; O75507; Q00839; Q8N174; Q96HY9; Q9BQ09"	"mRNA processing; lncRNA in canonical Wnt signaling and colorectal cancer"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"4"	"1"	"6199.4"	"5940.6"	"6022.4"	"5278.1"	"5778.5"	"5709.6"	"7223.0"	"8656.5"	"12421.7"	"22238.4"	"35762.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q09666"	"Neuroblast differentiation-associated protein AHNAK OS=Homo sapiens OX=9606 GN=AHNAK PE=1 SV=2"	"22"	"40"	"89"	"40"	"5890"	"628.7"	"6.15"	"17201.88"	"176.40"	"35"	"40"	"other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	""	"79026"	"ENSG00000124942"	"AHNAK"	"A1A586; hsa:79026; Q09666"	""	""	"0"	"0"	"1375.3"	"1227.9"	"1390.3"	"1146.6"	"1373.1"	"1408.9"	"1743.0"	"2507.3"	"8767.9"	"15563.4"	"22998.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75643"	"U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2"	"24"	"43"	"78"	"43"	"2136"	"244.4"	"6.06"	"13301.43"	"165.77"	"32"	"40"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00270, Pf00271, Pf02889, Pf18149"	"23020"	"ENSG00000144028"	"SNRNP200"	"hsa:23020; O75643; O94884; Q6NZY0; Q6PX59; Q8NBE6; Q96IF2; Q9H7S0"	"2q11.2 copy number variation syndrome"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"3"	"0"	"1611.9"	"1549.6"	"1726.7"	"1442.9"	"1638.4"	"1596.0"	"1983.2"	"2640.5"	"4770.9"	"14351.0"	"27784.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61978"	"Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1"	"52"	"23"	"80"	"23"	"463"	"50.9"	"5.54"	"15574.95"	"157.47"	"19"	"22"	"RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf08067"	"3190"	"ENSG00000165119"	"HNRNPK"	"hsa:3190; P61978; Q07244; Q15671; Q59F98; Q5T6W4; Q60577; Q6IBN1; Q922Y7; Q96J62"	"mRNA processing; lncRNA in canonical Wnt signaling and colorectal cancer"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA; HCMV Late Events; SUMOylation of RNA binding proteins"	"6"	"0"	"3832.7"	"4120.3"	"3870.3"	"3642.9"	"4118.5"	"3905.2"	"4601.1"	"5484.3"	"8526.2"	"15408.1"	"24851.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11142"	"Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1"	"54"	"34"	"86"	"27"	"646"	"70.9"	"5.52"	"15457.23"	"154.98"	"30"	"32"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00012"	"3312"	"ENSG00000109971"	"HSPA8"	"hsa:3312; P11142; Q9H3R6"	"Parkin-ubiquitin proteasomal system pathway; MAPK signaling pathway; Exercise-induced circadian regulation; Measles virus infection; Opioid receptor pathways; Extrafollicular and follicular B cell activation by SARS-CoV-2; 1p36 copy number variation syndrome"	"Clathrin-mediated endocytosis; Neutrophil degranulation; Late endosomal microautophagy; AUF1 (hnRNP D0) binds and destabilizes mRNA; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Regulation of HSF1-mediated heat shock response; Lysosome Vesicle Biogenesis; Golgi Associated Vesicle Biogenesis; mRNA Splicing - Major Pathway; CHL1 interactions; Interleukin-4 and Interleukin-13 signaling; GABA synthesis, release, reuptake and degradation; Lipophagy; Chaperone Mediated Autophagy; Protein methylation; Attenuation phase"	"24"	"7"	"3495.5"	"3062.6"	"3956.8"	"3301.4"	"3545.0"	"3753.7"	"4425.0"	"5634.2"	"10335.4"	"18736.4"	"27581.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09874"	"Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4"	"38"	"40"	"85"	"40"	"1014"	"113.0"	"8.88"	"17879.28"	"154.28"	"38"	"34"	"cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00533, Pf00644, Pf00645, Pf02877, Pf05406, Pf08063"	"142"	"ENSG00000143799"	"PARP1"	"B1ANJ4; hsa:142; P09874; Q8IUZ9"	"Corticotropin-releasing hormone signaling pathway; Nanoparticle triggered regulated necrosis; Fas ligand pathway and stress induction of heat shock proteins; NAD metabolism, sirtuins and aging; NAD+ metabolism; NAD+ biosynthetic pathways; Breast cancer pathway; Acute viral myocarditis; Joubert syndrome; Male infertility; Base excision repair; IL-18 signaling pathway; DNA repair pathways, full network; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Progeria-associated lipodystrophy; Primary ovarian insufficiency; A network map of Macrophage-stimulating protein (MSP) signaling"	"SUMOylation of DNA damage response and repair proteins; Downregulation of SMAD2/3:SMAD4 transcriptional activity; HDR through MMEJ (alt-NHEJ); Formation of Incision Complex in GG-NER; DNA Damage Recognition in GG-NER; vRNA Synthesis; POLB-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER"	"25"	"0"	"2498.7"	"2536.6"	"2647.1"	"2226.5"	"2684.7"	"2700.5"	"3496.2"	"5210.9"	"16066.6"	"25423.7"	"28396.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15149"	"Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3"	"11"	"42"	"73"	"39"	"4684"	"531.5"	"5.96"	"12782.91"	"152.67"	"31"	"40"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00681, Pf03501, Pf17902, Pf18373"	"5339"	"ENSG00000178209"	"PLEC"	"hsa:5339; Q15148; Q15149; Q16640; Q6S376; Q6S377; Q6S378; Q6S379; Q6S380; Q6S381; Q6S382; Q6S383"	"Envelope proteins and their potential roles in EDMD physiopathology"	"Assembly of collagen fibrils and other multimeric structures; Caspase-mediated cleavage of cytoskeletal proteins; Type I hemidesmosome assembly"	"4"	"2"	"2084.0"	"1969.1"	"2243.5"	"1827.0"	"2262.5"	"2291.3"	"2573.8"	"3248.7"	"5591.9"	"10619.1"	"16543.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P2Q9"	"Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2"	"19"	"38"	"70"	"38"	"2335"	"273.4"	"8.84"	"11450.77"	"148.78"	"26"	"36"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01398, Pf08082, Pf08083, Pf08084, Pf10596, Pf10597, Pf10598, Pf12134"	"10594"	"ENSG00000174231; ENSG00000274442"	"PRPF8"	"hsa:10594; O14547; O75965; Q6P2Q9"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"3"	"0"	"2342.7"	"2216.2"	"2483.0"	"2091.5"	"2475.5"	"2380.8"	"2805.3"	"3568.7"	"5907.2"	"17274.1"	"33742.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04406"	"Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3"	"61"	"19"	"49"	"19"	"335"	"36.0"	"8.46"	"6834.36"	"148.00"	"12"	"17"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00044, Pf02800"	"2597"	"ENSG00000111640"	"GAPDH"	"E7EUT4; hsa:2597; P00354; P04406; Q53X65"	"Cori cycle; Alzheimer's disease and miRNA effects; HIF1A and PPARG regulation of glycolysis; VEGFA-VEGFR2 signaling; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Aerobic glycolysis; 7q11.23 copy number variation syndrome; Glycolysis in senescence; Alzheimer's disease; Sildenafil treatment; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Glycolysis; Gluconeogenesis"	"16"	"0"	"2412.7"	"2561.0"	"2480.9"	"2069.0"	"2282.7"	"2260.6"	"2978.7"	"3903.8"	"6010.3"	"9764.6"	"14366.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q4VCS5"	"Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1"	"37"	"35"	"75"	"31"	"1084"	"118.0"	"7.64"	"13463.19"	"144.99"	"31"	"32"	"cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf12240"	"154796"	"ENSG00000126016"	"AMOT"	"hsa:154796; Q4VCS5; Q504X5; Q9HD27; Q9UPT1"	"VEGFA-VEGFR2 signaling; Hippo-Merlin signaling dysregulation; Pleural mesothelioma"	""	"3"	"4"	"2837.8"	"2607.9"	"2992.0"	"2593.4"	"2989.8"	"3001.2"	"3526.8"	"4128.1"	"6595.3"	"10790.3"	"16414.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04264"	"Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6"	"39"	"27"	"77"	"22"	"644"	"66.0"	"8.12"	"15205.13"	"144.67"	"26"	"26"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"bone, tooth or skin structural activity;other molecular function"	"Pf00038, Pf16208, Pf16210"	"3848"	"ENSG00000167768"	"KRT1"	"B2RA01; hsa:3848; P04264; P85925; P86104; Q14720; Q6GSJ0; Q9H298"	"Corticotropin-releasing hormone signaling pathway"	"Formation of the cornified envelope; Neutrophil degranulation"	"4"	"5"	"773.6"	"2133.3"	"2584.7"	"2101.9"	"3953.8"	"1291.3"	"2122.4"	"7632.2"	"4748.9"	"25359.8"	"9862.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31943"	"Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4"	"45"	"18"	"61"	"9"	"449"	"49.2"	"6.30"	"9911.00"	"144.46"	"12"	"16"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08080"	"3187"	"ENSG00000169045; ENSG00000284254"	"HNRNPH1"	"B3KW86; D3DWQ2; hsa:3187; P31943; Q6IBM4"	"MECP2 and associated Rett syndrome; mRNA processing; Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells"	"mRNA Splicing - Major Pathway; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA"	"6"	"11"	"3171.1"	"3627.1"	"2753.8"	"2421.3"	"2825.6"	"2841.2"	"3665.7"	"4476.1"	"6879.8"	"9896.7"	"13942.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14866"	"Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2"	"39"	"17"	"55"	"16"	"589"	"64.1"	"8.22"	"9458.75"	"139.84"	"10"	"17"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf11835, Pf13893"	"3191"	"ENSG00000104824; ENSG00000282947"	"HNRNPL"	"A6ND69; A6NIT8; hsa:3191; P14866; Q9H3P3"	"mRNA processing; Hippocampal synaptogenesis and neurogenesis"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"4"	"2"	"2472.6"	"2892.2"	"2594.7"	"2469.2"	"2643.7"	"2251.6"	"2942.2"	"3736.4"	"4372.6"	"6117.3"	"9354.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14980"	"Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2"	"25"	"43"	"83"	"42"	"2115"	"238.1"	"5.78"	"18073.04"	"139.14"	"40"	"37"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	""	"4926"	"ENSG00000137497"	"NUMA1"	"H0YH75; hsa:4926; Q14980; Q14981; Q9BTE9"	"Ectoderm differentiation; Ectoderm differentiation; 8p23.1 copy number variation syndrome"	"Recruitment of NuMA to mitotic centrosomes; Mitotic Prophase"	"5"	"1"	"2953.6"	"2580.7"	"3235.4"	"2611.5"	"3029.8"	"2992.3"	"3417.4"	"4040.8"	"6179.1"	"11155.4"	"17561.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13435"	"Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2"	"31"	"27"	"64"	"27"	"895"	"100.2"	"5.67"	"13003.42"	"137.18"	"25"	"24"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf02037, Pf04037, Pf04046"	"10992"	"ENSG00000087365"	"SF3B2"	"A8K485; B4DT19; hsa:10992; Q13435; Q7L4T5; Q7Z627; Q969K1; Q96CM6; Q9BWD2"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"3"	"0"	"4491.1"	"3529.0"	"4445.3"	"3870.9"	"4087.4"	"4381.0"	"5034.7"	"5541.3"	"6665.2"	"11253.0"	"19740.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P26639"	"Threonine--tRNA ligase 1, cytoplasmic OS=Homo sapiens OX=9606 GN=TARS1 PE=1 SV=3"	"53"	"35"	"73"	"35"	"723"	"83.4"	"6.67"	"13144.28"	"137.08"	"29"	"31"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol"	"nucleic acid binding activity;other molecular function"	"Pf00587, Pf02824, Pf03129, Pf07973"	"6897"	"ENSG00000113407"	"TARS1"	"A8K8I1; B4DEG8; hsa:6897; P26639; Q96FP5; Q9BWA6"	""	"Cytosolic tRNA aminoacylation"	"1"	"0"	"699.5"	"618.0"	"792.1"	"686.8"	"798.6"	"905.9"	"1575.6"	"4747.5"	"14234.8"	"23902.5"	"36576.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7KZF4"	"Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1"	"37"	"26"	"55"	"26"	"910"	"101.9"	"7.17"	"9329.64"	"136.30"	"18"	"26"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00565, Pf00567"	"27044"	"ENSG00000197157"	"SND1"	"hsa:27044; Q13122; Q7KZF4; Q96AG0"	"VEGFA-VEGFR2 signaling"	"Signaling by BRAF and RAF1 fusions"	"2"	"0"	"1047.3"	"984.5"	"1130.0"	"977.2"	"1126.1"	"1052.5"	"1325.7"	"1592.0"	"3803.7"	"11686.4"	"21725.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43491"	"Band 4.1-like protein 2 OS=Homo sapiens OX=9606 GN=EPB41L2 PE=1 SV=1"	"33"	"33"	"75"	"29"	"1005"	"112.5"	"5.44"	"14903.52"	"136.12"	"30"	"28"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf04382, Pf05902, Pf08736, Pf09379, Pf09380"	"2037"	"ENSG00000079819"	"EPB41L2"	"B4DHI8; E9PPD9; hsa:2037; O43491; Q5T4F0; Q68DV2"	"Splicing factor NOVA regulated synaptic proteins"	"Neurexins and neuroligins"	"2"	"4"	"3051.6"	"2577.2"	"3168.2"	"2654.3"	"2934.8"	"3139.9"	"3590.2"	"4230.6"	"9074.2"	"17431.9"	"26110.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08238"	"Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4"	"41"	"28"	"64"	"18"	"724"	"83.2"	"5.03"	"10705.10"	"135.68"	"23"	"27"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00183, Pf02518"	"3326"	"ENSG00000096384"	"HSP90AB1"	"B2R5P0; hsa:3326; P08238; Q5T9W7; Q9NQW0; Q9NTK6"	"Nuclear receptors meta-pathway; NRF2 pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway"	"Potential therapeutics for SARS; Regulation of actin dynamics for phagocytic cup formation; The role of GTSE1 in G2/M progression after G2 checkpoint; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Aryl hydrocarbon receptor signalling; Neutrophil degranulation; Estrogen-dependent gene expression; Sema3A PAK dependent Axon repulsion; DDX58/IFIH1-mediated induction of interferon-alpha/beta; The NLRP3 inflammasome; Purinergic signaling in leishmaniasis infection; RHOBTB2 GTPase cycle; Chaperone Mediated Autophagy; HSF1 activation; Attenuation phase; Uptake and function of diphtheria toxin"	"23"	"11"	"1998.0"	"2116.1"	"2221.6"	"1858.9"	"2135.5"	"2119.3"	"2549.8"	"3331.2"	"5528.6"	"9456.5"	"13248.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43390"	"Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1"	"50"	"28"	"64"	"18"	"633"	"70.9"	"8.13"	"11222.93"	"131.70"	"22"	"26"	"RNA metabolism OR transcription;other metabolic processes"	"ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf18360"	"10236"	"ENSG00000125944; ENSG00000282958"	"HNRNPR"	"hsa:10236; O43390; Q2L7G6; Q5TEH1; Q9BV64; S4R3J4"	"mRNA processing"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"3"	"10"	"3632.3"	"3549.5"	"3765.4"	"3271.5"	"3372.6"	"3396.7"	"4452.5"	"5754.2"	"7542.7"	"10539.5"	"15401.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P38646"	"Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2"	"43"	"29"	"60"	"28"	"679"	"73.6"	"6.16"	"11737.45"	"128.46"	"24"	"28"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00012"	"3313"	"ENSG00000113013"	"HSPA9"	"B2RCM1; hsa:3313; P30036; P31932; P38646; Q1HB43; Q53H23; Q6GU03; Q9BWB7; Q9UC56"	"Parkin-ubiquitin proteasomal system pathway; Iron-sulfur cluster biogenesis"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Regulation of HSF1-mediated heat shock response; Mitochondrial protein import; Cristae formation"	"6"	"0"	"3038.9"	"2940.1"	"3326.7"	"2795.4"	"3268.4"	"3174.7"	"3866.0"	"5120.6"	"8634.1"	"14102.2"	"20332.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12906"	"Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3"	"35"	"25"	"60"	"23"	"894"	"95.3"	"8.76"	"10273.71"	"126.54"	"20"	"24"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00035, Pf07528"	"3609"	"ENSG00000129351"	"ILF3"	"A8K6F2; G5E9M5; hsa:3609; O43409; Q12906; Q6P1X1; Q86XY7; Q99544; Q99545; Q9BZH4; Q9BZH5; Q9NQ95; Q9NQ96; Q9NQ97; Q9NQ98; Q9NQ99; Q9NQA0; Q9NQA1; Q9NQA2; Q9NRN2; Q9NRN3; Q9NRN4; Q9UMZ9; Q9UN00; Q9UN84; Q9UNA2"	""	"Regulation of CDH11 gene transcription"	"1"	"2"	"1689.8"	"1908.1"	"1799.6"	"1608.1"	"1816.0"	"1626.4"	"2132.2"	"2864.9"	"4426.9"	"7909.6"	"11933.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P54577"	"Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4"	"63"	"35"	"76"	"35"	"528"	"59.1"	"7.05"	"14540.94"	"122.75"	"33"	"31"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00579, Pf01588"	"8565"	"ENSG00000134684"	"YARS1"	"B3KWK4; D3DPQ4; hsa:8565; O43276; P54577; Q53EN1"	"Nephrotic syndrome"	"Cytosolic tRNA aminoacylation"	"2"	"0"	"2277.5"	"2138.2"	"2437.7"	"2019.1"	"2312.1"	"2285.4"	"2946.6"	"4271.2"	"13552.4"	"29114.8"	"39321.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q08211"	"ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4"	"23"	"26"	"65"	"26"	"1270"	"140.9"	"6.84"	"13036.08"	"122.05"	"23"	"23"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;cytoskeleton;translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00035, Pf00270, Pf00271, Pf04408, Pf07717"	"1660"	"ENSG00000135829"	"DHX9"	"B2RNV4; hsa:1660; Q05CI5; Q08211; Q12803; Q32Q22; Q5VY62; Q6PD69; Q99556"	"MECP2 and associated Rett syndrome; mRNA processing"	"mRNA Splicing - Major Pathway; RIP-mediated NFkB activation via ZBP1; DEx/H-box helicases activate type I IFN and inflammatory cytokines production"	"5"	"0"	"1386.1"	"1484.2"	"1418.3"	"1235.7"	"1406.6"	"1289.0"	"1753.8"	"2457.9"	"4023.6"	"7473.0"	"12754.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49792"	"E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2"	"14"	"36"	"63"	"27"	"3224"	"358.0"	"6.20"	"10059.99"	"120.86"	"28"	"33"	"protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00160, Pf00638, Pf00641, Pf12185"	"5903"	"ENSG00000153201"	"RANBP2"	"hsa:5903; P49792; Q13074; Q15280; Q53TE2; Q59FH7"	""	"HCMV Late Events; HCMV Early Events; Transcriptional regulation by small RNAs; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Signaling by ALK fusions and activated point mutants; tRNA processing in the nucleus; Separation of Sister Chromatids; Viral Messenger RNA Synthesis; SUMOylation of DNA damage response and repair proteins; Rev-mediated nuclear export of HIV RNA; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"35"	"9"	"2779.7"	"2330.2"	"2899.9"	"2588.9"	"2994.8"	"2806.8"	"3185.9"	"3842.6"	"6987.5"	"12957.6"	"18895.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92841"	"Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2"	"39"	"25"	"67"	"18"	"729"	"80.2"	"8.27"	"12938.13"	"120.59"	"23"	"23"	"RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"10521"	"ENSG00000100201"	"DDX17"	"B1AHM0; H3BLZ8; hsa:10521; Q69YT1; Q6ICD6; Q92841"	"Novel intracellular components of RIG-I-like receptor pathway"	"SUMOylation of transcription cofactors"	"2"	"6"	"2896.0"	"2729.3"	"2937.4"	"2609.6"	"2908.9"	"2571.1"	"3320.7"	"3928.8"	"4887.8"	"7846.3"	"12644.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P0DMV9"	"Heat shock 70 kDa protein 1B OS=Homo sapiens OX=9606 GN=HSPA1B PE=1 SV=1"	"48"	"31"	"62"	"25"	"641"	"70.0"	"5.66"	"10441.54"	"119.41"	"25"	"30"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00012"	"3303; 3304"	"ENSG00000204388; ENSG00000212866; ENSG00000224501; ENSG00000231555; ENSG00000232804"	"HSPA1B"	"B4E3B6; hsa:3303; hsa:3304; P08107; P0DMV9; P19790; Q5JQI4; Q5SP17; Q9UQL9; Q9UQM0"	"Apoptosis modulation and signaling; Parkin-ubiquitin proteasomal system pathway; MAPK signaling pathway; Apoptosis modulation by HSP70; VEGFA-VEGFR2 signaling; Measles virus infection; CKAP4 signaling pathway map"	"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Regulation of HSF1-mediated heat shock response; Neutrophil degranulation; Attenuation phase"	"12"	"0"	"2090.8"	"2188.0"	"2256.9"	"1993.5"	"2181.1"	"2374.8"	"2784.9"	"3591.0"	"6724.8"	"13171.0"	"20111.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00571"	"ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3"	"40"	"30"	"68"	"29"	"662"	"73.2"	"7.18"	"13811.91"	"117.34"	"28"	"26"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;translation activity;nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"1654"	"ENSG00000215301"	"DDX3X"	"A8K538; B4E3E8; hsa:1654; O00571; O15536"	"Novel intracellular components of RIG-I-like receptor pathway; Hepatitis B infection"	"Neutrophil degranulation"	"3"	"1"	"3768.1"	"3217.4"	"3748.5"	"3255.4"	"3582.9"	"3446.9"	"4326.0"	"5302.2"	"7287.8"	"10178.6"	"12862.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5JRX3"	"Presequence protease, mitochondrial OS=Homo sapiens OX=9606 GN=PITRM1 PE=1 SV=3"	"28"	"25"	"54"	"25"	"1037"	"117.3"	"6.92"	"10464.88"	"116.98"	"22"	"23"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport"	"mitochondrion"	"enzyme regulator activity;other molecular function"	"Pf00675, Pf05193, Pf08367"	"10531"	"ENSG00000107959"	"PITRM1"	"B3KMJ6; B4E0J8; C9JSL2; E7ES23; hsa:10531; O95204; Q2M2G6; Q4VBR1; Q5JRW7; Q5JRX3; Q7L5Z7; Q9BSI6; Q9BVJ5; Q9UPP8"	""	"Mitochondrial protein import"	"1"	"0"	"465.7"	"388.2"	"521.1"	"468.8"	"523.9"	"580.2"	"778.5"	"1875.8"	"7495.7"	"16138.7"	"24329.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07437"	"Tubulin beta chain OS=Homo sapiens OX=9606 GN=TUBB PE=1 SV=2"	"52"	"17"	"56"	"4"	"444"	"49.6"	"4.89"	"9456.16"	"114.25"	"14"	"16"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;other biological processes"	"non-structural extracellular;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00091, Pf03953"	"203068"	"ENSG00000183311; ENSG00000196230; ENSG00000224156; ENSG00000227739; ENSG00000229684; ENSG00000232421; ENSG00000232575; ENSG00000235067"	"TUBB"	"hsa:203068; P05218; P07437; Q8WUC1; Q9CY33"	"Alzheimer's disease and miRNA effects; Pathogenic Escherichia coli infection; Parkin-ubiquitin proteasomal system pathway; Opioid receptor pathways; Alzheimer's disease"	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Potential therapeutics for SARS; Neutrophil degranulation"	"14"	"14"	"1371.8"	"1576.8"	"1459.4"	"1291.8"	"1391.9"	"1313.2"	"1622.7"	"2192.4"	"3509.5"	"6100.7"	"8708.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P00558"	"Phosphoglycerate kinase 1 OS=Homo sapiens OX=9606 GN=PGK1 PE=1 SV=3"	"57"	"21"	"38"	"21"	"417"	"44.6"	"8.10"	"5898.26"	"108.84"	"10"	"20"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;other membranes;cytosol"	"kinase activity;other molecular function"	"Pf00162"	"5230"	"ENSG00000102144"	"PGK1"	"A8K4W6; B7Z7A9; hsa:5230; P00558; Q5J7W1; Q6IBT6; Q8NI87"	"Cori cycle; Photodynamic therapy-induced HIF-1 survival signaling; VEGFA-VEGFR2 signaling; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Aerobic glycolysis; Glycolysis in senescence; Warburg effect modulated by deubiquitinating enzymes and their substrates; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"Glycolysis; Gluconeogenesis; Manipulation of host energy metabolism"	"13"	"0"	"251.7"	"229.5"	"281.7"	"262.0"	"263.6"	"263.0"	"319.9"	"412.4"	"2491.7"	"13058.8"	"23546.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7KZ85"	"Transcription elongation factor SPT6 OS=Homo sapiens OX=9606 GN=SUPT6H PE=1 SV=2"	"22"	"29"	"54"	"29"	"1726"	"198.9"	"4.91"	"9808.28"	"107.79"	"24"	"24"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00575, Pf14632, Pf14633, Pf14635, Pf14639, Pf14641, Pf17674"	"6830"	"ENSG00000109111"	"SUPT6H"	"A7E2B4; hsa:6830; Q15737; Q6GMQ4; Q7KYW9; Q7KZ85; Q7LDK4; Q8N526; Q92775; Q96AH3; Q9BTH9; Q9BTI2"	""	"Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events"	"3"	"0"	"2902.3"	"2750.1"	"3178.3"	"3003.1"	"3081.7"	"2876.5"	"3616.0"	"4580.3"	"5735.0"	"7365.7"	"9064.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22102"	"Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1"	"29"	"24"	"43"	"24"	"1010"	"107.7"	"6.70"	"7628.99"	"106.49"	"17"	"23"	"other metabolic processes;developmental processes;other biological processes"	"cytosol"	"other molecular function"	"Pf00551, Pf00586, Pf01071, Pf02769, Pf02843, Pf02844"	"2618"	"ENSG00000159131; ENSG00000262473"	"GART"	"A8K945; A8KA32; D3DSF3; D3DSF4; hsa:2618; O14659; P22102; Q52M77"	"Folate metabolism; One-carbon metabolism; Metabolic reprogramming in colon cancer"	"Purine ribonucleoside monophosphate biosynthesis"	"4"	"0"	"574.9"	"553.0"	"657.5"	"559.9"	"724.0"	"951.2"	"1699.9"	"3387.8"	"6279.0"	"12007.8"	"18540.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14103"	"Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1"	"40"	"20"	"62"	"18"	"355"	"38.4"	"7.81"	"11367.98"	"106.32"	"19"	"18"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08143"	"3184"	"ENSG00000138668"	"HNRNPD"	"A8K9J2; hsa:3184; P07029; Q01858; Q14100; Q14101; Q14102; Q14103; Q4W5A1; Q9UCE8; Q9UCE9"	"mRNA processing"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"3"	"4"	"3602.4"	"4364.6"	"3643.5"	"3086.9"	"3411.9"	"2980.6"	"4229.8"	"5545.9"	"6854.3"	"9341.4"	"13688.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23284"	"Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2"	"63"	"20"	"52"	"20"	"216"	"23.7"	"9.41"	"9805.21"	"105.14"	"16"	"20"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00160"	"5479"	"ENSG00000166794"	"PPIB"	"A8K534; hsa:5479; P23284; Q6IBH5; Q9BVK5"	"Prolactin signaling pathway; Type I collagen synthesis in the context of osteogenesis imperfecta"	"Collagen biosynthesis and modifying enzymes; SARS-CoV-1 activates/modulates innate immune responses"	"4"	"0"	"1412.0"	"1527.9"	"1701.3"	"1682.8"	"2311.5"	"2783.5"	"4069.4"	"7270.9"	"16480.9"	"13400.1"	"9143.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P68371"	"Tubulin beta-4B chain OS=Homo sapiens OX=9606 GN=TUBB4B PE=1 SV=1"	"44"	"15"	"51"	"2"	"445"	"49.8"	"4.89"	"8530.34"	"103.45"	"12"	"14"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response"	"non-structural extracellular;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00091, Pf03953"	"10383"	"ENSG00000188229"	"TUBB4B"	"A2BFA2; hsa:10383; P05217; P68371"	"Alzheimer's disease and miRNA effects; Pathogenic Escherichia coli infection; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"Separation of Sister Chromatids; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; RHO GTPases Activate Formins; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; HCMV Early Events; Aggrephagy; EML4 and NUDC in mitotic spindle formation; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Neutrophil degranulation; COPI-dependent Golgi-to-ER retrograde traffic; Intraflagellar transport; Recycling pathway of L1; The role of GTSE1 in G2/M progression after G2 checkpoint; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane; Gap junction assembly; Formation of tubulin folding intermediates by CCT/TriC; Post-chaperonin tubulin folding pathway; RHO GTPases activate IQGAPs; Carboxyterminal post-translational modifications of tubulin; Assembly and cell surface presentation of NMDA receptors; Activation of AMPK downstream of NMDARs; Sealing of the nuclear envelope (NE) by ESCRT-III; Kinesins; Prefoldin mediated transfer of substrate  to CCT/TriC; Hedgehog 'off' state"	"41"	"0"	"111.2"	"137.6"	"126.5"	"105.7"	"98.0"	"121.1"	"159.8"	"184.3"	"241.0"	"394.4"	"565.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35579"	"Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4"	"16"	"25"	"38"	"19"	"1960"	"226.4"	"5.60"	"5817.67"	"102.54"	"14"	"23"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00063, Pf01576, Pf02736"	"4627"	"ENSG00000100345"	"MYH9"	"A8K6E4; hsa:4627; O60805; P35579; Q60FE2; Q86T83"	"Primary focal segmental glomerulosclerosis (FSGS); VEGFA-VEGFR2 signaling; Nephrotic syndrome"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Signaling by ALK fusions and activated point mutants; RHO GTPases activate CIT; EPHA-mediated growth cone collapse; Sema4D induced cell migration and growth-cone collapse; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; RHO GTPases activate PAKs; CD163 mediating an anti-inflammatory response"	"16"	"5"	"468.6"	"459.6"	"536.3"	"497.8"	"530.3"	"552.2"	"715.2"	"917.8"	"1436.1"	"5566.2"	"13478.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UQ80"	"Proliferation-associated protein 2G4 OS=Homo sapiens OX=9606 GN=PA2G4 PE=1 SV=3"	"47"	"20"	"56"	"20"	"394"	"43.8"	"6.55"	"11592.83"	"100.97"	"18"	"19"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"non-structural extracellular;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00557"	"5036"	"ENSG00000170515"	"PA2G4"	"hsa:5036; O43846; Q9UM59; Q9UQ80"	""	"Neutrophil degranulation"	"1"	"0"	"973.6"	"837.2"	"1089.2"	"901.3"	"1008.4"	"1071.8"	"1441.0"	"2512.0"	"10930.4"	"14038.8"	"14167.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P12956"	"X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2"	"35"	"23"	"55"	"23"	"609"	"69.8"	"6.64"	"12558.10"	"99.50"	"20"	"19"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02037, Pf02735, Pf03730, Pf03731"	"2547"	"ENSG00000196419"	"XRCC6"	"B1AHC8; hsa:2547; P12956; Q6FG89; Q9UCQ2; Q9UCQ3"	"Non-homologous end joining; DNA repair pathways, full network; Primary ovarian insufficiency"	"Neutrophil degranulation; Cytosolic sensors of pathogen-associated DNA ; Nonhomologous End-Joining (NHEJ); 2-LTR circle formation; IRF3-mediated induction of type I IFN"	"8"	"0"	"2626.7"	"2454.6"	"2642.8"	"2407.0"	"2636.6"	"2757.0"	"3203.2"	"3852.8"	"5796.5"	"9439.9"	"13239.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52597"	"Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3"	"39"	"16"	"46"	"13"	"415"	"45.6"	"5.58"	"5864.38"	"98.07"	"11"	"15"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf08080"	"3185"	"ENSG00000169813"	"HNRNPF"	"B3KM84; hsa:3185; P52597; Q5T0N2; Q96AU2"	"MECP2 and associated Rett syndrome"	"mRNA Splicing - Major Pathway; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	"5"	"0"	"2033.6"	"2178.0"	"1715.4"	"1532.5"	"1869.9"	"1896.5"	"2359.2"	"3103.8"	"4912.4"	"6372.4"	"7964.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15029"	"116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1"	"27"	"21"	"40"	"20"	"972"	"109.4"	"5.00"	"7664.28"	"97.68"	"16"	"21"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf00679, Pf03144, Pf03764, Pf14492, Pf16004"	"9343"	"ENSG00000108883"	"EFTUD2"	"B4DK30; B4DMC0; D3DX58; hsa:9343; K7EJ81; Q15029; Q9BUR0"	"mRNA processing; Ciliary landscape"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"4"	"0"	"1368.8"	"1350.9"	"1442.7"	"1204.7"	"1440.2"	"1435.7"	"1686.9"	"2139.9"	"3442.1"	"9256.2"	"18095.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13010"	"X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3"	"36"	"23"	"47"	"23"	"732"	"82.7"	"5.81"	"8808.23"	"97.50"	"17"	"20"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf02735, Pf03730, Pf03731, Pf08785"	"7520"	"ENSG00000079246"	"XRCC5"	"A8K3X5; hsa:7520; P13010; Q0Z7V0; Q4VBQ5; Q53HH7; Q7M4N0; Q9UCQ0; Q9UCQ1"	"Non-homologous end joining; Male infertility; DNA repair pathways, full network; p53 transcriptional gene network"	"Neutrophil degranulation; Cytosolic sensors of pathogen-associated DNA ; Nonhomologous End-Joining (NHEJ); 2-LTR circle formation; IRF3-mediated induction of type I IFN"	"9"	"0"	"1715.0"	"1473.7"	"1772.2"	"1521.2"	"1789.0"	"1780.6"	"2080.4"	"2461.5"	"3788.0"	"6615.0"	"9672.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62316"	"Small nuclear ribonucleoprotein Sm D2 OS=Homo sapiens OX=9606 GN=SNRPD2 PE=1 SV=1"	"69"	"12"	"68"	"12"	"118"	"13.5"	"9.91"	"15186.52"	"97.08"	"11"	"12"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf01423"	"6633"	"ENSG00000125743"	"SNRPD2"	"A8K797; hsa:6633; J3KPM5; P43330; P62316"	"mRNA processing"	"mRNA Splicing - Major Pathway; SARS-CoV-2 modulates host translation machinery; snRNP Assembly; mRNA Splicing - Minor Pathway"	"5"	"0"	"2009.6"	"1598.9"	"2228.5"	"1994.9"	"2014.4"	"1987.3"	"2222.2"	"2617.5"	"3131.3"	"4394.6"	"6728.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25205"	"DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3"	"38"	"22"	"42"	"22"	"808"	"90.9"	"5.77"	"6959.55"	"97.02"	"17"	"21"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf14551, Pf17207, Pf17855"	"4172"	"ENSG00000112118"	"MCM3"	"B4DWW4; hsa:4172; P25205; Q92660; Q9BTR3; Q9NUE7"	"Cell cycle; Retinoblastoma gene in cancer; Ciliary landscape; G1 to S cell cycle control; DNA replication"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"11"	"0"	"1684.6"	"1663.2"	"1772.4"	"1565.0"	"1679.1"	"1587.0"	"2081.3"	"2609.0"	"4091.6"	"7306.3"	"11024.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99459"	"Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2"	"35"	"24"	"49"	"24"	"802"	"92.2"	"8.18"	"9311.09"	"96.41"	"19"	"22"	"cell cycle OR cell proliferation;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf11831, Pf13921"	"988"	"ENSG00000096401"	"CDC5L"	"hsa:988; Q76N46; Q99459; Q99974"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"1482.9"	"1227.2"	"1585.2"	"1354.5"	"1536.5"	"1564.6"	"1939.7"	"2862.8"	"7279.1"	"15296.9"	"21309.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07814"	"Bifunctional glutamate/proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5"	"20"	"26"	"44"	"25"	"1512"	"170.5"	"7.33"	"7786.04"	"96.11"	"18"	"23"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00043, Pf00458, Pf00587, Pf00749, Pf03129, Pf03950, Pf09180"	"2058"	"ENSG00000136628"	"EPRS1"	"A0AVA9; B9EGH3; hsa:2058; P07814; Q05BP6; Q05DF8; Q5DSM1; Q5H9S5; Q6PD57; Q86X73"	"Parkinson's disease pathway; VEGFA-VEGFR2 signaling; Amino acid metabolism"	"tRNA modification in the nucleus and cytosol; Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"6"	"1"	"1486.6"	"1234.9"	"1579.4"	"1435.3"	"1606.4"	"1414.0"	"1735.3"	"2200.9"	"4445.9"	"10141.7"	"15394.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50991"	"T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4"	"49"	"19"	"34"	"19"	"539"	"57.9"	"7.83"	"5582.93"	"92.79"	"10"	"18"	"protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00118"	"10575"	"ENSG00000115484"	"CCT4"	"B2R6I3; B7Z8B1; F5H5W3; hsa:10575; O14870; P50991; Q53QP9; Q96C51"	"16p11.2 proximal deletion syndrome"	"Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; Folding of actin by CCT/TriC"	"7"	"0"	"826.8"	"771.4"	"907.7"	"811.8"	"862.2"	"897.2"	"1021.5"	"1286.8"	"2766.8"	"10334.4"	"23280.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H307"	"Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5"	"30"	"18"	"46"	"18"	"717"	"81.6"	"7.14"	"8639.99"	"91.77"	"16"	"16"	"cell adhesion;RNA metabolism OR transcription;other metabolic processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04696, Pf04697"	"5411"	"ENSG00000100941"	"PNN"	"B4DZX8; hsa:5411; O60899; Q53EM7; Q6P5X4; Q7KYL1; Q99738; Q9H307; Q9UHZ9; Q9UQR9"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"2111.8"	"1708.9"	"2363.2"	"2074.8"	"2136.2"	"2345.7"	"2655.7"	"2935.9"	"3710.1"	"5683.3"	"9626.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y383"	"Putative RNA-binding protein Luc7-like 2 OS=Homo sapiens OX=9606 GN=LUC7L2 PE=1 SV=2"	"36"	"16"	"42"	"12"	"392"	"46.5"	"10.01"	"7841.43"	"91.42"	"13"	"16"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03194"	"51631"	"ENSG00000146963"	"LUC7L2"	"B7Z500; hsa:51631; Q8IUP9; Q9NVL3; Q9NVN7; Q9UQN1; Q9Y383"	""	""	"0"	"6"	"795.1"	"734.9"	"833.3"	"728.7"	"845.3"	"866.6"	"1030.9"	"1376.1"	"4935.7"	"11572.8"	"16143.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P78527"	"DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3"	"7"	"26"	"50"	"26"	"4128"	"468.8"	"7.12"	"10298.92"	"91.31"	"24"	"22"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00454, Pf02259, Pf02260, Pf08163, Pf19704, Pf20502"	"5591"	"ENSG00000253729"	"PRKDC"	"hsa:5591; P78527; P78528; Q13327; Q13337; Q14175; Q59H99; Q7Z611; Q96SE6; Q9UME3"	"miRNA regulation of DNA damage response; Cell cycle; Retinoblastoma gene in cancer; Fas ligand pathway and stress induction of heat shock proteins; Pathways affected in adenoid cystic carcinoma; ATM signaling in development and disease ; Non-homologous end joining; Osteoblast differentiation and related diseases; DNA repair pathways, full network; DNA damage response"	"E3 ubiquitin ligases ubiquitinate target proteins; Cytosolic sensors of pathogen-associated DNA ; Nonhomologous End-Joining (NHEJ); IRF3-mediated induction of type I IFN"	"14"	"0"	"1324.9"	"1250.5"	"1417.5"	"1262.1"	"1381.9"	"1360.1"	"1530.0"	"2040.0"	"5196.9"	"9507.4"	"12667.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35908"	"Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2"	"31"	"22"	"56"	"16"	"639"	"65.4"	"8.00"	"10970.74"	"90.85"	"21"	"19"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;cytosol;cytoskeleton;other cell component"	"bone, tooth or skin structural activity;cytoskeletal activity"	"Pf00038, Pf16208"	"3849"	"ENSG00000172867"	"KRT2"	"hsa:3849; P35908; Q4VAQ2"	""	"Formation of the cornified envelope"	"2"	"3"	"659.3"	"1423.9"	"1463.1"	"1099.3"	"2586.5"	"785.9"	"1311.3"	"4014.0"	"1954.8"	"25685.8"	"5503.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14618"	"Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4"	"40"	"17"	"38"	"17"	"531"	"57.9"	"7.84"	"6995.78"	"89.87"	"14"	"16"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00224, Pf02887"	"5315"	"ENSG00000067225"	"PKM"	"A6NFK3; B2R5N8; B3KRY0; B4DFX8; B4DUU6; hsa:5315; P14618; P14786; Q53GK4; Q96E76; Q9BWB5; Q9UCV6; Q9UPF2"	"Photodynamic therapy-induced HIF-1 survival signaling; Amino acid metabolism; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Aerobic glycolysis; Glycolysis in senescence; Glucose metabolism in triple-negative breast cancer cells; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"Neutrophil degranulation"	"10"	"0"	"842.7"	"845.2"	"921.2"	"783.0"	"925.9"	"751.1"	"983.9"	"1288.8"	"2561.0"	"6717.8"	"13002.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75533"	"Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3"	"15"	"20"	"45"	"20"	"1304"	"145.7"	"7.09"	"8235.59"	"89.24"	"19"	"19"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf08920"	"23451"	"ENSG00000115524"	"SF3B1"	"E9PCH3; hsa:23451; O75533"	"mRNA processing; 10q11.21q11.23 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression; mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"5"	"0"	"2202.2"	"1681.0"	"2280.2"	"2106.1"	"2196.2"	"2264.1"	"2606.3"	"2900.9"	"3753.2"	"7395.2"	"12824.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15459"	"Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1"	"31"	"20"	"40"	"20"	"793"	"88.8"	"5.22"	"8724.45"	"89.14"	"17"	"19"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00240, Pf01805, Pf12230"	"10291"	"ENSG00000099995"	"SF3A1"	"E9PAW1; hsa:10291; Q15459"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"1231.1"	"1071.7"	"1268.1"	"1171.0"	"1286.7"	"1315.9"	"1494.2"	"1623.1"	"4042.8"	"10337.8"	"16144.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49750"	"YLP motif-containing protein 1 OS=Homo sapiens OX=9606 GN=YLPM1 PE=1 SV=4"	"12"	"22"	"42"	"22"	"2146"	"241.5"	"6.55"	"6854.36"	"88.78"	"16"	"21"	"other biological processes"	"cytosol;nucleus"	""	"Pf13671"	"56252"	"ENSG00000119596"	"YLPM1"	"hsa:56252; P49750; P49752; Q96I64; Q9P1V7"	""	""	"0"	"0"	"2168.8"	"1778.0"	"2168.0"	"1860.2"	"2153.5"	"2092.2"	"2356.5"	"2657.3"	"3638.7"	"5113.2"	"6528.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2L1"	"Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2"	"24"	"21"	"43"	"21"	"958"	"108.9"	"7.14"	"7912.72"	"88.65"	"17"	"21"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00773, Pf13638, Pf17215, Pf17216, Pf17849"	"22894"	"ENSG00000083520"	"DIS3"	"A6NI21; B2RBL2; hsa:22894; Q5W0P7; Q5W0P8; Q658Z7; Q7Z481; Q8WWI2; Q9UG36; Q9Y2L1"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	"6"	"0"	"847.9"	"827.0"	"1035.7"	"841.3"	"914.4"	"900.2"	"1193.2"	"1723.6"	"6070.9"	"9424.0"	"10804.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07910"	"Heterogeneous nuclear ribonucleoproteins C1/C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4"	"38"	"20"	"58"	"20"	"306"	"33.7"	"5.08"	"12729.27"	"88.54"	"19"	"16"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"3183"	"ENSG00000092199"	"HNRNPC"	"D3DS19; D3DS22; hsa:3183; P07910; P22628; Q53EX2; Q59FD3; Q5FWE8; Q86SF8; Q86U45; Q96HK7; Q96HM4; Q96IY5; Q9BTS3"	"mRNA processing"	"Processing of Capped Intron-Containing Pre-mRNA; SUMOylation of RNA binding proteins; mRNA Splicing - Major Pathway; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle"	"6"	"0"	"4032.4"	"3944.4"	"4177.1"	"3578.1"	"4013.3"	"4042.7"	"4862.6"	"5165.6"	"5901.7"	"8793.5"	"13253.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P24928"	"DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2"	"17"	"27"	"48"	"27"	"1970"	"217.0"	"7.37"	"9077.98"	"88.19"	"24"	"23"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00623, Pf04983, Pf04990, Pf04992, Pf04997, Pf04998, Pf05000, Pf05001"	"5430"	""	"POLR2A"	"A6NN93; B9EH88; hsa:5430; P24928; Q6NX41"	"Pyrimidine metabolism; Eukaryotic transcription initiation; mRNA processing"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"44"	"0"	"2221.9"	"2027.4"	"2475.1"	"2248.1"	"2435.7"	"2508.0"	"2881.7"	"3547.1"	"4823.4"	"7542.8"	"10739.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63241"	"Eukaryotic translation initiation factor 5A-1 OS=Homo sapiens OX=9606 GN=EIF5A PE=1 SV=2"	"68"	"8"	"51"	"8"	"154"	"16.8"	"5.24"	"8790.51"	"87.48"	"6"	"8"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf01287"	"1984"	"ENSG00000132507; ENSG00000288145"	"EIF5A"	"A8K9A0; D3DTP2; hsa:1984; P10159; P63241; Q16182; Q7L7L3; Q7Z4L1; Q9D0G2"	"Translation factors; eIF5A regulation in response to inhibition of the nuclear export system"	"Hypusine synthesis from eIF5A-lysine"	"3"	"0"	"261.4"	"275.4"	"314.6"	"269.3"	"308.4"	"331.2"	"458.4"	"1742.6"	"9156.1"	"13297.7"	"23951.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12874"	"Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1"	"35"	"18"	"39"	"18"	"501"	"58.8"	"5.38"	"6630.75"	"87.39"	"12"	"16"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf11931, Pf12108, Pf13297, Pf16837"	"10946"	"ENSG00000183431"	"SF3A3"	"D3DPT5; hsa:10946; Q12874; Q15460; Q5VT87"	"Exercise-induced circadian regulation; mRNA processing"	"mRNA Splicing - Major Pathway"	"3"	"0"	"1168.2"	"1020.5"	"1154.0"	"1027.7"	"1159.3"	"1228.9"	"1405.6"	"1742.6"	"3691.0"	"9252.2"	"14888.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22234"	"Multifunctional protein ADE2 OS=Homo sapiens OX=9606 GN=PAICS PE=1 SV=3"	"37"	"16"	"39"	"16"	"425"	"47.0"	"7.23"	"7559.71"	"87.08"	"12"	"13"	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00731, Pf01259"	"10606"	"ENSG00000128050"	"PAICS"	"E9PDH9; hsa:10606; P22234; Q68CQ5"	"Metabolic reprogramming in colon cancer"	"Purine ribonucleoside monophosphate biosynthesis"	"2"	"0"	"740.5"	"762.0"	"909.8"	"758.2"	"842.8"	"675.7"	"1003.3"	"1133.8"	"2503.6"	"9388.0"	"14662.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P10809"	"60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2"	"31"	"20"	"46"	"20"	"573"	"61.0"	"5.87"	"9969.21"	"86.66"	"19"	"20"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00118"	"3329"	"ENSG00000144381"	"HSPD1"	"B2R5M6; B7Z712; hsa:3329; P10809; Q38L19; Q9UCR6"	"Apoptosis-related network due to altered Notch3 in ovarian cancer; 8p23.1 copy number variation syndrome; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Mitochondrial protein import; TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"	"5"	"0"	"2146.9"	"2199.2"	"2370.2"	"1979.7"	"2344.2"	"2168.2"	"2589.7"	"3452.6"	"5487.0"	"8495.5"	"16853.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P17987"	"T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1"	"44"	"17"	"32"	"17"	"556"	"60.3"	"6.11"	"4758.39"	"86.60"	"8"	"17"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf00118"	"6950"	"ENSG00000120438"	"TCP1"	"E1P5B2; hsa:6950; P17987; Q15556; Q5TCM3"	"16p11.2 proximal deletion syndrome"	"Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; Folding of actin by CCT/TriC"	"8"	"0"	"411.1"	"459.3"	"484.7"	"383.3"	"460.5"	"464.2"	"541.0"	"781.4"	"2026.9"	"7000.8"	"13488.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12955"	"Ankyrin-3 OS=Homo sapiens OX=9606 GN=ANK3 PE=1 SV=3"	"7"	"22"	"41"	"19"	"4377"	"480.1"	"6.49"	"7461.24"	"86.25"	"19"	"22"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00531, Pf00791, Pf12796, Pf17809"	"288"	"ENSG00000151150"	"ANK3"	"B1AQT2; B4DIL1; E9PE32; hsa:288; Q12955; Q13484; Q5CZH9; Q5VXD5; Q7Z3G4; Q9H0P5"	"Splicing factor NOVA regulated synaptic proteins"	"COPI-mediated anterograde transport; Interaction between L1 and Ankyrins"	"3"	"3"	"1560.1"	"1404.3"	"1627.9"	"1473.5"	"1574.2"	"1493.9"	"1838.8"	"2318.6"	"4227.7"	"6161.8"	"7611.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60891"	"Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2"	"57"	"16"	"39"	"8"	"318"	"34.8"	"6.98"	"7082.50"	"86.15"	"13"	"15"	"other metabolic processes;developmental processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf13793, Pf14572"	"5631"	"ENSG00000147224"	"PRPS1"	"B1ALA8; B2R6T7; B4DNL6; D3DUX6; hsa:5631; P09329; P60891"	""	"5-Phosphoribose 1-diphosphate biosynthesis"	"1"	"8"	"1133.3"	"1648.2"	"1306.3"	"1033.4"	"1194.7"	"1217.1"	"1591.6"	"2446.0"	"4634.3"	"8448.6"	"11721.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01081"	"Splicing factor U2AF 35 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF1 PE=1 SV=3"	"36"	"9"	"30"	"9"	"240"	"27.9"	"8.81"	"5102.86"	"84.90"	"4"	"9"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00642"	"102724594; 7307"	"ENSG00000160201"	"U2AF1"	"hsa:102724594; hsa:7307; Q01081; Q701P4; Q71RF1"	"mRNA processing"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"5"	"0"	"308.8"	"306.7"	"345.4"	"294.4"	"305.8"	"257.7"	"372.8"	"543.3"	"2048.4"	"4573.4"	"6497.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09651"	"Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5"	"35"	"16"	"43"	"13"	"372"	"38.7"	"9.13"	"8714.74"	"84.48"	"10"	"13"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf11627"	"3178"	"ENSG00000135486"	"HNRNPA1"	"A8K4Z8; hsa:3178; P09651; Q3MIB7; Q6PJZ7"	"mRNA processing"	"mRNA Splicing - Major Pathway; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA; SARS-CoV-1-host interactions; SARS-CoV-1 modulates host translation machinery"	"6"	"0"	"1941.9"	"2076.5"	"1732.2"	"1486.8"	"1632.2"	"1649.9"	"2084.5"	"2664.0"	"2700.0"	"3595.5"	"5038.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14979"	"Heterogeneous nuclear ribonucleoprotein D-like OS=Homo sapiens OX=9606 GN=HNRNPDL PE=1 SV=3"	"31"	"15"	"43"	"13"	"420"	"46.4"	"9.57"	"9189.60"	"84.40"	"14"	"15"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity"	"Pf00076"	"9987"	"ENSG00000152795"	"HNRNPDL"	"hsa:9987; O14979; Q6SPF2; Q7KZ74; Q7KZ75; Q96IM0; Q96S43"	""	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	"1"	"0"	"1949.8"	"1740.4"	"1919.4"	"1709.8"	"1852.1"	"1288.3"	"2134.0"	"2603.2"	"3073.1"	"4418.4"	"6491.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43290"	"U4/U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1"	"31"	"20"	"39"	"20"	"800"	"90.2"	"6.13"	"7657.16"	"84.10"	"16"	"18"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	""	"Pf03343, Pf19252"	"9092"	"ENSG00000175467"	"SART1"	"A6NDN1; hsa:9092; O43290; Q53GB5"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"2267.8"	"2053.0"	"2421.8"	"2083.5"	"2338.3"	"2283.0"	"2663.9"	"3014.6"	"3928.2"	"6032.6"	"8830.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P21333"	"Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4"	"10"	"21"	"35"	"20"	"2647"	"280.6"	"6.06"	"6488.18"	"83.75"	"15"	"20"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00307, Pf00630"	"2316"	"ENSG00000196924"	"FLNA"	"E9KL45; hsa:2316; P21333; Q5HY53; Q5HY55; Q8NF52"	"Androgen receptor signaling pathway; Prolactin signaling pathway; Focal adhesion; Hypothesized pathways in pathogenesis of cardiovascular disease; MAPK signaling pathway; IL-4 signaling pathway; Ebola virus infection in host; Joubert syndrome; NPHP1 deletion syndrome"	"OAS antiviral response; Platelet degranulation ; RHO GTPases activate PAKs; GP1b-IX-V activation signalling; Cell-extracellular matrix interactions"	"14"	"0"	"748.8"	"682.6"	"782.1"	"713.5"	"799.9"	"732.2"	"894.0"	"1120.9"	"1935.0"	"6444.4"	"14042.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52272"	"Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3"	"33"	"20"	"43"	"20"	"730"	"77.5"	"8.70"	"6926.58"	"83.45"	"18"	"19"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf11532"	"4670"	"ENSG00000099783"	"HNRNPM"	"hsa:4670; P52272; Q15584; Q8WZ44; Q96H56; Q9BWL9; Q9Y492"	"mRNA processing"	"mRNA Splicing - Major Pathway; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA"	"4"	"0"	"1806.4"	"1705.1"	"2049.0"	"1715.3"	"2047.8"	"1941.3"	"2311.9"	"2831.2"	"4925.9"	"9335.7"	"14559.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95602"	"DNA-directed RNA polymerase I subunit RPA1 OS=Homo sapiens OX=9606 GN=POLR1A PE=1 SV=2"	"17"	"21"	"40"	"20"	"1720"	"194.7"	"7.03"	"7358.35"	"82.49"	"16"	"19"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00623, Pf04983, Pf04997, Pf04998, Pf05000"	"25885"	"ENSG00000068654"	"POLR1A"	"B7Z7T0; D6W5M0; hsa:25885; O95602; Q0VG05; Q9UEH0; Q9UFT9"	"Pyrimidine metabolism; Eukaryotic transcription initiation; 2q13 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"8"	"1"	"604.0"	"541.7"	"689.6"	"610.6"	"650.9"	"639.1"	"820.2"	"1650.5"	"5349.1"	"10817.7"	"14656.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55795"	"Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1"	"38"	"14"	"40"	"7"	"449"	"49.2"	"6.30"	"7141.17"	"82.42"	"11"	"12"	"other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf00076, Pf08080"	"3188"	"ENSG00000126945"	"HNRNPH2"	"A1L400; hsa:3188; P55795; Q9HHA7"	"mRNA processing"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"3"	"0"	"526.0"	"509.2"	"574.3"	"479.1"	"542.4"	"610.0"	"717.3"	"988.6"	"1899.7"	"2974.8"	"4302.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50990"	"T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4"	"38"	"18"	"34"	"18"	"548"	"59.6"	"5.60"	"5817.53"	"80.80"	"13"	"18"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00118"	"10694"	"ENSG00000156261"	"CCT8"	"A6NN54; B4DEM7; B4DQH4; hsa:10694; P50990; Q4VBP8"	"16p11.2 proximal deletion syndrome"	"Association of TriC/CCT with target proteins during biosynthesis; Neutrophil degranulation; Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; Folding of actin by CCT/TriC"	"8"	"0"	"518.2"	"460.2"	"584.9"	"502.2"	"575.5"	"552.9"	"671.8"	"878.0"	"1732.0"	"7500.3"	"17537.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13645"	"Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6"	"29"	"19"	"48"	"14"	"584"	"58.8"	"5.21"	"9591.37"	"80.34"	"18"	"16"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;cytosol;cytoskeleton;other cell component"	"bone, tooth or skin structural activity;other molecular function"	"Pf00038"	"3858"	"ENSG00000186395"	"KRT10"	"hsa:3858; P13645; Q14664; Q8N175"	""	"Formation of the cornified envelope"	"2"	"6"	"665.9"	"1507.9"	"1458.5"	"1514.7"	"2534.4"	"813.0"	"1365.2"	"5094.4"	"3229.2"	"32393.0"	"6903.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q93009"	"Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2"	"18"	"15"	"35"	"15"	"1102"	"128.2"	"5.55"	"7009.10"	"80.30"	"12"	"14"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00443, Pf00917, Pf12436, Pf14533"	"7874"	"ENSG00000187555"	"USP7"	"A6NMY8; B7Z815; H0Y3G8; hsa:7874; Q93009"	"Nucleotide excision repair in xeroderma pigmentosum ; Warburg effect modulated by deubiquitinating enzymes and their substrates"	"Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Ub-specific processing proteases; Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Regulation of TP53 Degradation; Formation of TC-NER Pre-Incision Complex; Regulation of PTEN localization"	"10"	"0"	"708.7"	"713.7"	"804.5"	"713.6"	"821.5"	"793.5"	"949.2"	"1228.9"	"2225.0"	"5490.7"	"9988.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P68363"	"Tubulin alpha-1B chain OS=Homo sapiens OX=9606 GN=TUBA1B PE=1 SV=1"	"42"	"14"	"33"	"2"	"451"	"50.1"	"5.06"	"5706.12"	"80.16"	"10"	"14"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00091, Pf03953"	"10376"	"ENSG00000123416"	"TUBA1B"	"hsa:10376; P04687; P05209; P68363; Q27I68; Q8WU19"	"Alzheimer's disease and miRNA effects; Pathogenic Escherichia coli infection; Allograft rejection; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"Recruitment of NuMA to mitotic centrosomes; Recycling pathway of L1; COPI-dependent Golgi-to-ER retrograde traffic; MHC class II antigen presentation; Kinesins; HCMV Early Events; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Intraflagellar transport; Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane; Gap junction assembly; Resolution of Sister Chromatid Cohesion; Formation of tubulin folding intermediates by CCT/TriC; Post-chaperonin tubulin folding pathway; RHO GTPases activate IQGAPs; RHO GTPases Activate Formins; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Carboxyterminal post-translational modifications of tubulin; Assembly and cell surface presentation of NMDA receptors; Activation of AMPK downstream of NMDARs; Aggrephagy; EML4 and NUDC in mitotic spindle formation; Sealing of the nuclear envelope (NE) by ESCRT-III; Hedgehog 'off' state; RHOH GTPase cycle"	"35"	"12"	"1002.6"	"1348.9"	"1061.0"	"945.0"	"1057.9"	"1011.4"	"1285.9"	"1766.1"	"2905.9"	"5691.8"	"8369.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15393"	"Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4"	"22"	"20"	"37"	"20"	"1217"	"135.5"	"5.26"	"6544.65"	"79.82"	"16"	"20"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03178, Pf10433"	"23450"	"ENSG00000189091"	"SF3B3"	"hsa:23450; Q15393; Q6NTI8; Q96GC0; Q9BPY2; Q9UFX7; Q9UJ29"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"3"	"0"	"1049.0"	"1072.5"	"1108.1"	"972.8"	"1153.0"	"1149.9"	"1381.3"	"1904.8"	"3073.5"	"7349.0"	"14636.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60506"	"Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2"	"30"	"19"	"46"	"9"	"623"	"69.6"	"8.59"	"9056.91"	"79.76"	"18"	"17"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf18360"	"10492"	"ENSG00000135316"	"SYNCRIP"	"E1P501; E1P502; hsa:10492; O60506; Q53H05; Q5TCG2; Q5TCG3; Q8IW78; Q8N599; Q96LC1; Q96LC2; Q9Y583"	""	""	"0"	"0"	"813.8"	"765.8"	"956.2"	"795.6"	"868.4"	"861.4"	"1022.4"	"1288.0"	"2317.3"	"4400.1"	"6875.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35611"	"Alpha-adducin OS=Homo sapiens OX=9606 GN=ADD1 PE=1 SV=2"	"25"	"17"	"34"	"15"	"737"	"80.9"	"5.83"	"5833.70"	"78.88"	"13"	"17"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00596"	"118"	"ENSG00000087274"	"ADD1"	"A2A3N8; A2A3P0; B4DI79; D3DVR3; D3DVR4; D3DVR5; hsa:118; P35611; Q13734; Q14729; Q16156; Q86XM2; Q9UJB6"	""	"XBP1(S) activates chaperone genes; Caspase-mediated cleavage of cytoskeletal proteins; Miscellaneous transport and binding events"	"3"	"2"	"1240.9"	"947.4"	"1234.3"	"1116.2"	"1254.8"	"1159.1"	"1343.9"	"1681.0"	"5409.9"	"6640.8"	"7464.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P42285"	"Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3"	"22"	"19"	"45"	"19"	"1042"	"117.7"	"6.52"	"8592.43"	"78.58"	"17"	"17"	"RNA metabolism OR transcription;other metabolic processes;stress response"	"nucleus"	"other molecular function"	"Pf00270, Pf00271, Pf08148, Pf13234"	"23517"	"ENSG00000039123"	"MTREX"	"hsa:23517; P42285; Q2M386; Q6MZZ8; Q6P170; Q8N5R0; Q8TAG2"	""	"mRNA Splicing - Major Pathway; Major pathway of rRNA processing in the nucleolus and cytosol"	"2"	"0"	"1005.0"	"911.0"	"1165.2"	"991.9"	"1041.0"	"1062.2"	"1289.1"	"1695.5"	"4749.4"	"9290.2"	"13744.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14868"	"Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2"	"37"	"17"	"40"	"17"	"501"	"57.1"	"6.55"	"8202.14"	"78.26"	"16"	"16"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00152, Pf01336"	"1615"	"ENSG00000115866"	"DARS1"	"A8K3J2; D3DP77; hsa:1615; P14868; Q2TNI3; Q32Q69; Q53HV4; Q53YC5; Q68CR9; Q9BW52"	"Alanine and aspartate metabolism"	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"3"	"0"	"475.1"	"480.7"	"517.5"	"430.4"	"504.1"	"511.3"	"692.5"	"1140.2"	"4329.7"	"11430.2"	"17077.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86XP3"	"ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1"	"26"	"22"	"40"	"22"	"938"	"102.9"	"7.02"	"7314.79"	"77.86"	"18"	"20"	"other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"11325"	"ENSG00000198231"	"DDX42"	"A6NML1; A8KA43; hsa:11325; O75619; Q68G51; Q86XP3; Q96BK1; Q96HR7; Q9Y3V8"	""	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"2"	"0"	"1779.8"	"1856.6"	"1633.5"	"1600.9"	"1749.5"	"1715.1"	"2025.8"	"2375.6"	"3099.8"	"4514.8"	"5964.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63010"	"AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1"	"22"	"19"	"43"	"10"	"937"	"104.5"	"5.38"	"7927.22"	"77.57"	"17"	"16"	"transport;developmental processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01602, Pf02883, Pf09066"	"163"	"ENSG00000006125"	"AP2B1"	"A6NJP3; hsa:163; P21851; P63010; Q7Z451; Q96J19"	"Synaptic vesicle pathway; GABA receptor signaling; EGF/EGFR signaling pathway; Fragile X syndrome; mBDNF and proBDNF regulation of GABA neurotransmission; Markers of kidney cell lineage; 17q12 copy number variation syndrome"	"Recycling pathway of L1; MHC class II antigen presentation; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; Potential therapeutics for SARS; EPH-ephrin mediated repulsion of cells; LDL clearance; Nef Mediated CD4 Down-regulation; Retrograde neurotrophin signalling; Nef Mediated CD8 Down-regulation; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; VLDLR internalisation and degradation"	"20"	"8"	"809.5"	"752.2"	"885.2"	"795.7"	"939.7"	"1131.7"	"2663.9"	"6690.6"	"8456.8"	"9475.7"	"9243.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46013"	"Proliferation marker protein Ki-67 OS=Homo sapiens OX=9606 GN=MKI67 PE=1 SV=2"	"11"	"28"	"45"	"27"	"3256"	"358.5"	"9.45"	"8815.69"	"77.38"	"23"	"22"	"cell cycle OR cell proliferation;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00498, Pf08065, Pf15276"	"4288"	"ENSG00000148773"	"MKI67"	"hsa:4288; P46013; Q5VWH2"	"Primary focal segmental glomerulosclerosis (FSGS)"	""	"1"	"1"	"2340.6"	"2083.7"	"2410.7"	"1992.9"	"2349.9"	"2413.2"	"2832.0"	"2931.6"	"4684.5"	"7003.9"	"8385.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96N67"	"Dedicator of cytokinesis protein 7 OS=Homo sapiens OX=9606 GN=DOCK7 PE=1 SV=4"	"13"	"24"	"44"	"24"	"2140"	"242.4"	"6.80"	"8379.32"	"77.19"	"22"	"20"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"other cell component"	"enzyme regulator activity;other molecular function"	"Pf06920, Pf11878, Pf14429, Pf20421, Pf20422"	"85440"	"ENSG00000116641"	"DOCK7"	"hsa:85440; Q00M63; Q2PPY7; Q45RE8; Q45RE9; Q5T1B9; Q5T1C0; Q6ZV32; Q8TB82; Q96N67; Q96NG6; Q96NI0; Q9C092"	""	"Factors involved in megakaryocyte development and platelet production; RAC1 GTPase cycle; CDC42 GTPase cycle; MET activates RAP1 and RAC1"	"4"	"0"	"1258.0"	"1136.7"	"1308.1"	"1159.5"	"1392.0"	"1445.6"	"2009.2"	"3127.7"	"5804.9"	"9575.6"	"11732.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19338"	"Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3"	"30"	"25"	"51"	"25"	"710"	"76.6"	"4.70"	"8576.71"	"77.16"	"23"	"20"	"developmental processes;other biological processes"	"plasma membrane;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"4691"	"ENSG00000115053"	"NCL"	"hsa:4691; P19338; Q53SK1; Q8NB06; Q9UCF0; Q9UDG1"	"Pathogenic Escherichia coli infection; VEGFA-VEGFR2 signaling"	"Major pathway of rRNA processing in the nucleolus and cytosol"	"3"	"0"	"4397.9"	"3876.7"	"4206.9"	"3698.7"	"4175.9"	"4347.9"	"5000.1"	"5439.8"	"8427.8"	"13425.8"	"15783.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P40926"	"Malate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=MDH2 PE=1 SV=3"	"48"	"15"	"44"	"15"	"338"	"35.5"	"8.68"	"8214.35"	"76.85"	"15"	"14"	"other metabolic processes"	"other membranes;mitochondrion;other cell component"	"other molecular function"	"Pf00056, Pf02866"	"4191"	"ENSG00000146701"	"MDH2"	"A8K414; B2RE78; B4DE44; E9PDB2; hsa:4191; O43682; P40926"	"Amino acid metabolism; Metabolic reprogramming in colon cancer; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders; TCA cycle (aka Krebs or citric acid cycle)"	"Gluconeogenesis; Citric acid cycle (TCA cycle)"	"8"	"0"	"1572.8"	"1551.1"	"1624.9"	"1404.3"	"1608.8"	"1620.0"	"1912.3"	"2081.1"	"5120.4"	"11599.4"	"12869.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05455"	"Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2"	"45"	"20"	"45"	"20"	"408"	"46.8"	"7.12"	"9077.41"	"76.83"	"19"	"18"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf05383, Pf08777"	"6741"	"ENSG00000138385"	"SSB"	"hsa:6741; P05455; Q15367; Q53XJ4"	""	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Termination"	"2"	"0"	"2523.2"	"2288.8"	"2435.6"	"2067.8"	"2552.7"	"2864.8"	"3165.7"	"3806.1"	"6275.4"	"9876.9"	"13459.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P78371"	"T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4"	"29"	"12"	"31"	"12"	"535"	"57.5"	"6.46"	"6259.03"	"76.82"	"7"	"10"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00118"	"10576"	"ENSG00000166226"	"CCT2"	"A8K402; B5BTY7; B7Z243; B7Z7K4; B7ZAT2; hsa:10576; P78371; Q14D36; Q6IAT3"	"16p11.2 proximal deletion syndrome"	"Neutrophil degranulation; Formation of tubulin folding intermediates by CCT/TriC; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; RHOBTB2 GTPase cycle; Folding of actin by CCT/TriC; BBSome-mediated cargo-targeting to cilium; RHOBTB1 GTPase cycle"	"10"	"0"	"304.6"	"319.2"	"362.7"	"300.9"	"324.1"	"308.7"	"403.8"	"573.5"	"1165.3"	"4643.4"	"10594.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P40939"	"Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2"	"28"	"17"	"38"	"17"	"763"	"82.9"	"9.04"	"6494.23"	"76.48"	"14"	"17"	"other metabolic processes;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf00378, Pf00725, Pf02737"	"3030"	"ENSG00000084754"	"HADHA"	"B2R7L4; B4DYP2; hsa:3030; P40939; Q16679; Q53T69; Q53TA2; Q96GT7; Q9UQC5"	"Fatty acid beta-oxidation; Mitochondrial long chain fatty acid beta-oxidation; Valproic acid pathway; Mitochondrial fatty acid oxidation disorders; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Acyl chain remodeling of CL; mitochondrial fatty acid beta-oxidation of unsaturated fatty acids; Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA; Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of myristoyl-CoA to lauroyl-CoA; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA; Beta oxidation of palmitoyl-CoA to myristoyl-CoA"	"13"	"0"	"981.0"	"996.2"	"1035.4"	"889.2"	"1041.7"	"1039.0"	"1271.1"	"1625.2"	"3329.3"	"7603.3"	"12180.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P27695"	"DNA-(apurinic or apyrimidinic site) lyase OS=Homo sapiens OX=9606 GN=APEX1 PE=1 SV=2"	"55"	"14"	"34"	"14"	"318"	"35.5"	"8.12"	"7422.87"	"76.44"	"13"	"13"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;mitochondrion;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03372"	"328"	"ENSG00000100823"	"APEX1"	"hsa:328; P27695; Q969L5; Q99775"	"Thyroid stimulating hormone (TSH) signaling pathway; Spinal cord injury; Base excision repair; DNA repair pathways, full network"	"Displacement of DNA glycosylase by APEX1; POLB-Dependent Long Patch Base Excision Repair; PCNA-Dependent Long Patch Base Excision Repair; Abasic sugar-phosphate removal via the single-nucleotide replacement pathway"	"10"	"0"	"869.8"	"842.0"	"925.6"	"811.8"	"936.3"	"891.3"	"1183.0"	"1609.2"	"5599.4"	"7567.8"	"7237.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HB71"	"Calcyclin-binding protein OS=Homo sapiens OX=9606 GN=CACYBP PE=1 SV=2"	"54"	"18"	"42"	"17"	"228"	"26.2"	"8.25"	"9095.64"	"76.35"	"15"	"14"	"developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf04969, Pf05002, Pf09032"	"27101"	"ENSG00000116161"	"CACYBP"	"B2ZWH2; B3KSF1; hsa:27101; O60666; Q5R370; Q5R371; Q9HB71"	"Gastric cancer network 2"	""	"1"	"1"	"1026.4"	"849.4"	"1013.5"	"869.6"	"1095.7"	"1227.2"	"2402.4"	"6173.5"	"9945.9"	"15563.1"	"25461.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UQ35"	"Serine/arginine repetitive matrix protein 2 OS=Homo sapiens OX=9606 GN=SRRM2 PE=1 SV=2"	"10"	"18"	"31"	"18"	"2752"	"299.4"	"12.06"	"4777.10"	"76.23"	"12"	"18"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf08312"	"23524"	"ENSG00000167978"	"SRRM2"	"A6NKB9; D3DU97; hsa:23524; O15038; O94803; Q6NSL3; Q6PIM3; Q6PK40; Q8IW17; Q96GY7; Q9P0G1; Q9UHA8; Q9UQ35; Q9UQ36; Q9UQ37; Q9UQ38; Q9UQ40"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"1434.9"	"1211.4"	"1491.0"	"1358.5"	"1410.4"	"1367.3"	"1658.5"	"1885.9"	"2711.3"	"5967.2"	"10457.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11021"	"Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2"	"38"	"24"	"47"	"22"	"654"	"72.3"	"5.16"	"10086.13"	"76.12"	"22"	"21"	"protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;nucleus;other cell component"	"translation activity;other molecular function"	"Pf00012"	"3309"	"ENSG00000044574"	"HSPA5"	"B0QZ61; hsa:3309; P11021; Q2EF78; Q9NPF1; Q9UK02"	"Parkin-ubiquitin proteasomal system pathway; Apoptosis-related network due to altered Notch3 in ovarian cancer; Photodynamic therapy-induced unfolded protein response; Prion disease pathway; Unfolded protein response; Orexin receptor pathway"	"Regulation of HSF1-mediated heat shock response; Platelet degranulation ; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; ATF6B (ATF6-beta) activates chaperones; IRE1alpha activates chaperones; PERK regulates gene expression; ATF6 (ATF6-alpha) activates chaperone genes"	"14"	"0"	"1572.8"	"1473.5"	"1847.0"	"1612.6"	"1759.2"	"1788.4"	"2024.4"	"2600.3"	"5023.1"	"9994.3"	"15461.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15233"	"Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4"	"33"	"16"	"41"	"15"	"471"	"54.2"	"8.95"	"7846.56"	"75.89"	"12"	"16"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08075"	"4841"	"ENSG00000147140"	"NONO"	"B7Z4C2; D3DVV4; F5GYZ3; hsa:4841; O00201; P30807; Q12786; Q15233; Q9BQC5"	"mRNA processing"	""	"1"	"0"	"2592.5"	"2110.3"	"2669.4"	"2351.8"	"2559.3"	"2514.8"	"2956.7"	"3256.4"	"4240.7"	"5535.4"	"7869.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30101"	"Protein disulfide-isomerase A3 OS=Homo sapiens OX=9606 GN=PDIA3 PE=1 SV=4"	"47"	"19"	"30"	"19"	"505"	"56.7"	"6.35"	"4597.75"	"75.70"	"10"	"18"	"cell adhesion;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"non-structural extracellular;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00085, Pf13848"	"2923"	"ENSG00000167004"	"PDIA3"	"hsa:2923; P30101; Q13453; Q14255; Q8IYF8; Q9UMU7"	"Prion disease pathway"	"ER-Phagosome pathway; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Calnexin/calreticulin cycle"	"4"	"0"	"373.0"	"396.7"	"445.6"	"397.7"	"477.1"	"448.8"	"543.5"	"688.6"	"1237.4"	"6901.8"	"18041.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43776"	"Asparagine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=NARS1 PE=1 SV=1"	"30"	"16"	"38"	"16"	"548"	"62.9"	"6.25"	"8383.38"	"75.54"	"14"	"15"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00152, Pf01336"	"4677"	"ENSG00000134440"	"NARS1"	"B4DG16; hsa:4677; O43776; Q53GU6"	"Photodynamic therapy-induced unfolded protein response"	"Cytosolic tRNA aminoacylation"	"2"	"0"	"1547.0"	"1519.2"	"1631.2"	"1384.8"	"1627.0"	"1577.8"	"1965.9"	"2660.6"	"7356.2"	"11237.2"	"10296.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q00688"	"Peptidyl-prolyl cis-trans isomerase FKBP3 OS=Homo sapiens OX=9606 GN=FKBP3 PE=1 SV=1"	"46"	"15"	"41"	"15"	"224"	"25.2"	"9.28"	"7727.35"	"75.27"	"15"	"14"	""	"nucleus"	"other molecular function"	"Pf00254, Pf18410"	"2287"	"ENSG00000100442"	"FKBP3"	"B2R4Q9; hsa:2287; Q00688; Q14317"	""	""	"0"	"0"	"2181.6"	"1899.2"	"2332.3"	"2020.3"	"2138.5"	"2259.4"	"2865.6"	"4043.4"	"7567.2"	"11615.5"	"15357.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23246"	"Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2"	"25"	"18"	"43"	"17"	"707"	"76.1"	"9.44"	"8616.41"	"75.25"	"16"	"15"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08075"	"6421"	"ENSG00000116560"	"SFPQ"	"hsa:6421; P23246; P30808; Q5SZ71"	"mRNA processing; Type 2 papillary renal cell carcinoma"	"Suppression of apoptosis; PTK6 Regulates Proteins Involved in RNA Processing"	"4"	"1"	"3430.8"	"3277.2"	"3314.6"	"2937.8"	"3282.8"	"3237.4"	"3934.9"	"4287.4"	"5440.9"	"7380.9"	"10596.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06748"	"Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2"	"49"	"19"	"50"	"19"	"294"	"32.6"	"4.78"	"11155.41"	"74.68"	"17"	"17"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;translation activity;nucleic acid binding activity;other molecular function"	"Pf03066, Pf16276"	"4869"	"ENSG00000181163"	"NPM1"	"A8K3N7; B5BU00; D3DQL6; hsa:4869; P06748; P08693; Q12826; Q13440; Q13441; Q14115; Q5EU94; Q5EU95; Q5EU96; Q5EU97; Q5EU98; Q5EU99; Q6V962; Q8WTW5; Q96AT6; Q96DC4; Q96EA5; Q9BYG9; Q9UDJ7"	""	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain; Nuclear import of Rev protein; Deposition of new CENPA-containing nucleosomes at the centromere; SUMOylation of transcription cofactors; ALK mutants bind TKIs; Nuclear events stimulated by ALK signaling in cancer; TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation; SARS-CoV-1-host interactions"	"9"	"0"	"6938.3"	"5908.2"	"6653.1"	"6196.9"	"6202.8"	"6205.1"	"7406.0"	"7862.6"	"10007.3"	"13338.8"	"15064.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BXP5"	"Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1"	"31"	"23"	"41"	"23"	"876"	"100.6"	"5.96"	"7286.75"	"74.60"	"19"	"20"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04959, Pf12066"	"51593"	"ENSG00000087087"	"SRRT"	"A4D2E5; A4D2E6; A6NK22; B4DJL4; B4DZA6; hsa:51593; O95808; Q32MI4; Q6NT74; Q8TDQ5; Q9BWP6; Q9BXP4; Q9BXP5; Q9Y4S4"	""	"mRNA Splicing - Major Pathway; RNA polymerase II transcribes snRNA genes"	"2"	"0"	"1315.0"	"1271.0"	"1434.4"	"1243.4"	"1475.1"	"1346.5"	"1632.0"	"1976.2"	"2903.9"	"9674.9"	"17646.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04075"	"Fructose-bisphosphate aldolase A OS=Homo sapiens OX=9606 GN=ALDOA PE=1 SV=2"	"44"	"18"	"45"	"14"	"364"	"39.4"	"8.09"	"9627.44"	"74.26"	"18"	"15"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00274"	"226"	"ENSG00000149925"	"ALDOA"	"B4DXI7; hsa:226; P04075; Q6FH76; Q6FI10; Q96B15; Q9BWD9; Q9UCN2"	"VEGFA-VEGFR2 signaling; Clear cell renal cell carcinoma pathways; Aerobic glycolysis; 16p11.2 proximal deletion syndrome; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Glycolysis; Gluconeogenesis; Neutrophil degranulation; Platelet degranulation"	"11"	"4"	"2905.1"	"2984.6"	"2883.8"	"2337.9"	"3010.2"	"2883.5"	"3729.0"	"4941.3"	"6635.2"	"11049.7"	"18795.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q71U36"	"Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1"	"39"	"13"	"30"	"1"	"451"	"50.1"	"5.06"	"5240.58"	"73.96"	"9"	"13"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00091, Pf03953"	"7846"	"ENSG00000167552"	"TUBA1A"	"A8K0B8; G3V1U9; hsa:7846; P04687; P05209; Q71U36"	"Alzheimer's disease and miRNA effects; Pathogenic Escherichia coli infection; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease; PAFAH1B1 copy number variation"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Recycling pathway of L1; MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Recruitment of mitotic centrosome proteins and complexes; Formation of tubulin folding intermediates by CCT/TriC; Prefoldin mediated transfer of substrate  to CCT/TriC; HCMV Early Events; COPI-dependent Golgi-to-ER retrograde traffic; Kinesins; Intraflagellar transport; The role of GTSE1 in G2/M progression after G2 checkpoint; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane; Gap junction assembly; Recruitment of NuMA to mitotic centrosomes; Post-chaperonin tubulin folding pathway; RHO GTPases activate IQGAPs; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Carboxyterminal post-translational modifications of tubulin; Assembly and cell surface presentation of NMDA receptors; Activation of AMPK downstream of NMDARs; Aggrephagy; Sealing of the nuclear envelope (NE) by ESCRT-III; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Hedgehog 'off' state"	"41"	"0"	"77.8"	"60.0"	"83.5"	"82.0"	"79.9"	"56.7"	"83.1"	"123.2"	"258.4"	"526.4"	"903.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99729"	"Heterogeneous nuclear ribonucleoprotein A/B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2"	"28"	"14"	"39"	"13"	"332"	"36.2"	"8.21"	"6698.37"	"72.86"	"13"	"13"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08143"	"3182"	"ENSG00000197451"	"HNRNPAB"	"B3KNN5; D3DWP7; hsa:3182; Q04150; Q8N7U3; Q99729; Q9BQ99"	"Pre-implantation embryo; mRNA processing"	""	"2"	"0"	"2882.4"	"2643.0"	"3111.7"	"2765.2"	"2896.9"	"2613.5"	"3455.8"	"3834.7"	"4254.5"	"5894.7"	"9026.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P15311"	"Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4"	"37"	"24"	"48"	"15"	"586"	"69.4"	"6.27"	"9862.55"	"72.39"	"24"	"18"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf00769, Pf09379, Pf09380, Pf20492"	"7430"	"ENSG00000092820"	"EZR"	"E1P5A8; hsa:7430; P15311; P23714; Q4VX75; Q96CU8; Q9NSJ4"	"Pathogenic Escherichia coli infection; AGE/RAGE pathway; VEGFA-VEGFR2 signaling; 16p11.2 proximal deletion syndrome; CCL18 signaling pathway; Regulation of actin cytoskeleton; GDNF signaling"	"Recycling pathway of L1; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Netrin-1 signaling"	"11"	"9"	"2083.6"	"1914.5"	"2149.3"	"1732.3"	"2136.2"	"2177.8"	"2661.3"	"3556.9"	"9719.3"	"12966.8"	"11449.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UMS4"	"Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1"	"37"	"12"	"30"	"12"	"504"	"55.1"	"6.61"	"4698.70"	"71.80"	"9"	"12"	"cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00400, Pf04564, Pf08606"	"27339"	"ENSG00000110107"	"PRPF19"	"hsa:27339; Q9UMS4"	""	"mRNA Splicing - Major Pathway; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of TC-NER Pre-Incision Complex"	"5"	"0"	"424.9"	"379.6"	"495.0"	"425.1"	"451.2"	"436.4"	"595.9"	"989.1"	"3573.3"	"9892.2"	"14402.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P15924"	"Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3"	"8"	"21"	"41"	"21"	"2871"	"331.6"	"6.81"	"7737.97"	"71.26"	"19"	"18"	"cell adhesion;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00681, Pf17902, Pf18373"	"1832"	"ENSG00000096696"	"DSP"	"B2RTT2; D7RX09; hsa:1832; O75993; P15924; Q14189; Q9UHN4"	"Arrhythmogenic right ventricular cardiomyopathy; Lung fibrosis; Epithelial to mesenchymal transition in colorectal cancer"	"Neutrophil degranulation; Formation of the cornified envelope; RND3 GTPase cycle; RND1 GTPase cycle; Apoptotic cleavage of cell adhesion  proteins"	"9"	"0"	"1654.2"	"1530.4"	"1656.3"	"1522.6"	"1755.2"	"1612.6"	"1952.7"	"2401.4"	"3371.1"	"6261.9"	"8954.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43852"	"Calumenin OS=Homo sapiens OX=9606 GN=CALU PE=1 SV=2"	"54"	"16"	"32"	"16"	"315"	"37.1"	"4.64"	"6269.51"	"71.22"	"12"	"15"	""	"non-structural extracellular;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf13833"	"813"	"ENSG00000128595"	"CALU"	"B3KPG9; D6QS48; D6QS49; D6QS50; D6QS51; D6QS52; D6QS53; D6QS54; D6QS55; D6QS56; D6QS57; D6QS58; D6QS59; F5H1Q9; F5H879; hsa:813; O43852; O60456; Q6FHB9; Q96RL3; Q9NR43"	"NOTCH1 regulation of endothelial cell calcification; VEGFA-VEGFR2 signaling"	"Platelet degranulation ; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation"	"5"	"0"	"1828.6"	"1506.4"	"1828.6"	"1752.6"	"1935.1"	"2053.8"	"2244.7"	"2294.4"	"2560.9"	"2911.4"	"3859.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92945"	"Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4"	"32"	"17"	"32"	"14"	"711"	"73.1"	"7.30"	"6261.48"	"70.80"	"14"	"14"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf09005"	"8570"	"ENSG00000088247"	"KHSRP"	"hsa:8570; O00301; Q59EZ9; Q5U4P6; Q92945; Q9UNT5; Q9UQH5"	"Pre-implantation embryo"	"ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA"	"3"	"3"	"1981.0"	"1882.7"	"1986.4"	"1744.3"	"1936.3"	"2015.8"	"2354.1"	"2670.4"	"3579.2"	"4982.2"	"7253.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52948"	"Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4"	"12"	"19"	"42"	"19"	"1817"	"197.5"	"6.40"	"7909.32"	"70.74"	"17"	"18"	"cell organization and biogenesis;protein metabolism;transport;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04096, Pf12110"	"4928"	"ENSG00000110713"	"NUP98"	"hsa:4928; P52948; Q8IUT2; Q8WYB0; Q96E54; Q9H3Q4; Q9NT02; Q9UF57; Q9UHX0; Q9Y6J4; Q9Y6J5"	"SARS-CoV-2 innate immunity evasion and cell-specific immune response"	""	"1"	"0"	"1955.5"	"1911.5"	"1995.9"	"1771.3"	"1968.1"	"2091.5"	"2435.9"	"2986.0"	"3928.1"	"5696.4"	"7847.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P68104"	"Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1"	"39"	"15"	"39"	"7"	"462"	"50.1"	"9.01"	"5815.72"	"70.49"	"12"	"14"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;translational apparatus;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03143, Pf03144"	"1915"	"ENSG00000156508"	"EEF1A1"	"hsa:1915; P04719; P04720; P68104; Q6IQ15"	"Translation factors; Fragile X syndrome; 2q37 copy number variation syndrome"	"Neutrophil degranulation; Peptide chain elongation; Chaperone Mediated Autophagy; Protein methylation; HSF1 activation; SARS-CoV-1 modulates host translation machinery"	"10"	"9"	"2914.6"	"3353.5"	"2474.0"	"2023.4"	"2514.6"	"2675.6"	"3186.3"	"3778.9"	"7787.4"	"13827.2"	"15712.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P57740"	"Nuclear pore complex protein Nup107 OS=Homo sapiens OX=9606 GN=NUP107 PE=1 SV=1"	"18"	"14"	"32"	"14"	"925"	"106.3"	"5.43"	"6639.43"	"69.84"	"13"	"11"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes"	"other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf04121"	"57122"	"ENSG00000111581"	"NUP107"	"B4DZ67; hsa:57122; P57740; Q6PJE1"	"Gastric cancer network 1; Primary ovarian insufficiency"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Transport of Mature mRNA Derived from an Intronless Transcript; tRNA processing in the nucleus; SUMOylation of RNA binding proteins; Regulation of HSF1-mediated heat shock response; HCMV Late Events; HCMV Early Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); SARS-CoV-2 activates/modulates innate and adaptive immune responses; Postmitotic nuclear pore complex (NPC) reformation"	"37"	"0"	"1289.0"	"1291.9"	"1414.5"	"1277.7"	"1445.0"	"1374.2"	"1643.5"	"2157.4"	"3009.6"	"5514.5"	"8611.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43719"	"HIV Tat-specific factor 1 OS=Homo sapiens OX=9606 GN=HTATSF1 PE=1 SV=1"	"25"	"17"	"30"	"17"	"755"	"85.8"	"4.40"	"5048.62"	"69.69"	"11"	"16"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	"Pf00076"	"27336"	"ENSG00000102241"	"HTATSF1"	"D3DWG9; hsa:27336; O43719; Q59G06; Q99730"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"1297.5"	"1100.4"	"1346.6"	"1222.4"	"1315.6"	"1304.5"	"1543.4"	"1825.2"	"3480.5"	"6887.7"	"12267.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13573"	"SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1"	"36"	"18"	"36"	"18"	"536"	"61.5"	"9.52"	"7181.05"	"69.63"	"16"	"15"	"RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus"	"signal transduction activity or receptor binding;other molecular function"	"Pf02731"	"22938"	"ENSG00000100603"	"SNW1"	"A8K8A9; hsa:22938; Q13483; Q13573; Q32N03; Q5D0D6"	"Novel intracellular components of RIG-I-like receptor pathway; Splicing factor NOVA regulated synaptic proteins; Notch signaling pathway"	"mRNA Splicing - Major Pathway; Formation of paraxial mesoderm; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Pre-NOTCH Transcription and Translation; Downregulation of SMAD2/3:SMAD4 transcriptional activity; NOTCH1 Intracellular Domain Regulates Transcription; Notch-HLH transcription pathway; NOTCH3 Intracellular Domain Regulates Transcription; Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells; NOTCH4 Intracellular Domain Regulates Transcription; RUNX3 regulates NOTCH signaling"	"15"	"0"	"2278.1"	"2350.0"	"2314.4"	"2058.4"	"2271.9"	"2300.2"	"2812.5"	"3275.4"	"4256.8"	"7624.7"	"12619.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P17844"	"Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1"	"34"	"23"	"46"	"16"	"614"	"69.1"	"8.92"	"9369.25"	"69.42"	"22"	"18"	"RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf08061"	"1655"	"ENSG00000108654"	"DDX5"	"B4DLW8; B5BU21; D3DU32; E7ETL9; hsa:1655; O75681; P17844; Q53Y61"	"Ciliary landscape"	"mRNA Splicing - Major Pathway; SUMOylation of transcription cofactors; Estrogen-dependent gene expression; Replication of the SARS-CoV-1 genome; Replication of the SARS-CoV-2 genome"	"6"	"0"	"3096.3"	"2791.8"	"3236.6"	"2728.6"	"2927.6"	"2962.5"	"3466.1"	"3861.2"	"4855.5"	"6844.6"	"10691.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15366"	"Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1"	"36"	"10"	"26"	"5"	"365"	"38.6"	"6.79"	"4286.71"	"68.41"	"7"	"10"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013"	"5094"	"ENSG00000197111"	"PCBP2"	"A8K7X6; B4DXP5; F8VYL7; G3V0E8; hsa:5094; I6L8F9; Q15366; Q32Q82; Q59HD4; Q68Y55; Q6IPF4; Q6PKG5"	"mRNA processing; Ferroptosis; Modulators of TCR signaling and T cell activation"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA; Negative regulators of DDX58/IFIH1 signaling; SARS-CoV-1 activates/modulates innate immune responses"	"7"	"6"	"966.9"	"1102.6"	"1111.8"	"921.9"	"989.6"	"1027.8"	"1295.3"	"1700.1"	"2635.9"	"4439.9"	"6354.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NZW5"	"MAGUK p55 subfamily member 6 OS=Homo sapiens OX=9606 GN=MPP6 PE=1 SV=2"	"30"	"17"	"36"	"15"	"540"	"61.1"	"6.18"	"6156.27"	"67.98"	"14"	"17"	"cell organization and biogenesis"	"plasma membrane;other membranes;other cell component"	""	"Pf00595, Pf00625, Pf02828, Pf07653"	"51678"	"ENSG00000105926"	"PALS2"	"A4D157; hsa:51678; Q9H0E1; Q9NZW5"	""	""	"0"	"2"	"977.8"	"905.0"	"1088.2"	"930.9"	"1040.1"	"1031.1"	"1240.1"	"1541.4"	"4305.8"	"10063.1"	"14319.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60216"	"Double-strand-break repair protein rad21 homolog OS=Homo sapiens OX=9606 GN=RAD21 PE=1 SV=2"	"25"	"13"	"27"	"13"	"631"	"71.6"	"4.65"	"3990.05"	"67.86"	"7"	"13"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04824, Pf04825"	"5885"	"ENSG00000164754"	"RAD21"	"A8K0E0; hsa:5885; O60216; Q15001; Q99568"	"Cell cycle; Prion disease pathway; Regulation of sister chromatid separation at the metaphase-anaphase transition; Cohesin complex - Cornelia de Lange syndrome; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; 10q22q23 copy number variation"	"Meiotic synapsis; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; SUMOylation of DNA damage response and repair proteins; Estrogen-dependent gene expression; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"13"	"0"	"703.8"	"695.1"	"745.6"	"656.8"	"754.9"	"756.4"	"894.8"	"1069.1"	"1921.5"	"4382.1"	"6529.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35580"	"Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3"	"13"	"19"	"28"	"13"	"1976"	"228.9"	"5.54"	"4616.77"	"67.77"	"11"	"17"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00063, Pf00612, Pf01576, Pf02736"	"4628"	"ENSG00000133026"	"MYH10"	"B2RWP9; D3DTS1; F8VTL3; hsa:4628; P35580; Q12989; Q149N3; Q149N4; Q16087; Q4LE45; Q6PK16; Q9BWG0"	"Regulation of actin cytoskeleton"	"EPHA-mediated growth cone collapse; RHO GTPases activate PAKs; RHO GTPases activate CIT; Sema4D induced cell migration and growth-cone collapse; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs"	"7"	"1"	"588.6"	"463.6"	"949.6"	"601.2"	"832.9"	"666.4"	"825.8"	"911.2"	"1602.0"	"4680.0"	"9029.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2J2"	"Band 4.1-like protein 3 OS=Homo sapiens OX=9606 GN=EPB41L3 PE=1 SV=2"	"19"	"18"	"37"	"13"	"1087"	"120.6"	"5.19"	"7066.27"	"67.29"	"15"	"16"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf04382, Pf05902, Pf08736, Pf09379, Pf09380"	"23136"	"ENSG00000082397"	"EPB41L3"	"B7Z4I5; F5GX05; hsa:23136; O95713; Q9BRP5; Q9Y2J2"	"Splicing factor NOVA regulated synaptic proteins"	"Neurexins and neuroligins; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea"	"4"	"0"	"1650.9"	"1286.0"	"1630.0"	"1483.7"	"1533.1"	"1667.3"	"1966.3"	"2576.1"	"5774.0"	"3622.6"	"3651.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TAF3"	"WD repeat-containing protein 48 OS=Homo sapiens OX=9606 GN=WDR48 PE=1 SV=1"	"35"	"15"	"31"	"15"	"677"	"76.2"	"7.03"	"4683.56"	"66.90"	"10"	"14"	"DNA metabolism;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00400, Pf11816"	"57599"	"ENSG00000114742"	"WDR48"	"B4DM86; B4DQI2; B4DY84; hsa:57599; Q63HJ2; Q658Y1; Q8N3Z1; Q8TAF3; Q9NSK8; Q9P279"	"DNA repair pathways, full network"	"Ub-specific processing proteases; Fanconi Anemia Pathway; Signaling by cytosolic PDGFRA and PDGFRB fusion proteins; Recognition of DNA damage by PCNA-containing replication complex"	"5"	"0"	"352.9"	"334.4"	"404.5"	"371.9"	"427.0"	"436.3"	"580.5"	"1081.2"	"2541.6"	"5361.4"	"5706.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86VP6"	"Cullin-associated NEDD8-dissociated protein 1 OS=Homo sapiens OX=9606 GN=CAND1 PE=1 SV=2"	"19"	"15"	"31"	"15"	"1230"	"136.3"	"5.78"	"6037.37"	"66.70"	"13"	"15"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf08623"	"55832"	"ENSG00000111530"	"CAND1"	"B2RAU3; hsa:55832; O94918; Q6PIY4; Q86VP6; Q8NDJ4; Q96JZ9; Q96T19; Q9BTC4; Q9H0G2; Q9P0H7; Q9UF85"	"Endoderm differentiation"	"Neutrophil degranulation; Neddylation; Iron uptake and transport"	"4"	"0"	"342.6"	"361.3"	"433.6"	"350.9"	"401.1"	"414.4"	"512.2"	"684.2"	"2772.8"	"6141.9"	"8401.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NYF8"	"Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2"	"18"	"16"	"35"	"15"	"920"	"106.1"	"9.98"	"6771.69"	"66.56"	"13"	"16"	"stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf15440"	"9774"	"ENSG00000029363"	"BCLAF1"	"A2RU75; B7ZM58; E1P586; hsa:9774; Q14673; Q86WU6; Q86WY0; Q9NYF8"	"Interactome of polycomb repressive complex 2 (PRC2)"	""	"1"	"0"	"2072.3"	"1937.7"	"2040.1"	"1777.5"	"2001.0"	"2052.6"	"2372.3"	"2740.0"	"3426.5"	"6642.7"	"12215.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49368"	"T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4"	"38"	"17"	"33"	"17"	"545"	"60.5"	"6.49"	"5692.67"	"66.43"	"12"	"15"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00118"	"7203"	"ENSG00000163468"	"CCT3"	"A6NE14; hsa:7203; P49368; Q5SZY1; Q9BR64"	"16p11.2 proximal deletion syndrome"	"Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; Folding of actin by CCT/TriC"	"7"	"0"	"463.0"	"405.5"	"552.8"	"495.8"	"532.5"	"522.9"	"632.9"	"786.4"	"1716.8"	"8516.5"	"19080.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P48643"	"T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1"	"30"	"16"	"27"	"16"	"541"	"59.6"	"5.66"	"4090.08"	"66.21"	"8"	"14"	"protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00118"	"22948"	"ENSG00000150753"	"CCT5"	"A8JZY8; A8K2X8; B4DYD8; hsa:22948; P48643"	"16p11.2 proximal deletion syndrome"	"Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; Folding of actin by CCT/TriC"	"7"	"0"	"739.4"	"734.6"	"850.3"	"740.3"	"759.6"	"801.7"	"955.6"	"1246.5"	"2311.4"	"9791.5"	"22618.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q06830"	"Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1"	"60"	"16"	"38"	"15"	"199"	"22.1"	"8.13"	"7415.65"	"66.03"	"14"	"14"	"cell cycle OR cell proliferation;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00578, Pf10417"	"5052"	"ENSG00000117450"	"PRDX1"	"B5BU26; D3DPZ8; hsa:5052; P35703; Q06830; Q2V576; Q5T154; Q5T155"	"Androgen receptor signaling pathway; Selenium micronutrient network; Nuclear receptors meta-pathway; NRF2 pathway"	"Detoxification of Reactive Oxygen Species; TP53 Regulates Metabolic Genes; NFE2L2 regulating anti-oxidant/detoxification enzymes; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"	"8"	"1"	"1464.1"	"1404.8"	"1590.0"	"1537.3"	"1422.0"	"1357.3"	"1807.3"	"2389.9"	"4381.2"	"9718.6"	"15951.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P54136"	"Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2"	"25"	"16"	"32"	"16"	"660"	"75.3"	"6.68"	"7454.57"	"65.73"	"13"	"14"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00750, Pf03485, Pf05746"	"5917"	"ENSG00000113643"	"RARS1"	"B2RBS9; hsa:5917; P54136; Q53GY4; Q9BWA1"	"Amino acid metabolism"	"Cytosolic tRNA aminoacylation; Selenoamino acid metabolism"	"3"	"0"	"370.5"	"374.1"	"425.9"	"371.6"	"400.7"	"400.7"	"514.3"	"803.9"	"2831.8"	"7878.9"	"11853.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKV3"	"Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2"	"17"	"19"	"37"	"19"	"1341"	"151.8"	"6.43"	"7104.39"	"65.64"	"15"	"16"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02037, Pf16294"	"22985"	"ENSG00000100813"	"ACIN1"	"B2RTT4; D3DS45; hsa:22985; O75158; Q9UG91; Q9UKV1; Q9UKV2; Q9UKV3"	""	"mRNA Splicing - Major Pathway; Apoptotic cleavage of cellular proteins"	"2"	"0"	"3111.8"	"2777.3"	"3222.7"	"2658.0"	"2950.0"	"2872.3"	"3439.7"	"3774.4"	"4643.1"	"7840.0"	"13620.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86UP2"	"Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1"	"11"	"12"	"28"	"11"	"1357"	"156.2"	"5.64"	"5691.16"	"64.75"	"10"	"12"	"transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi"	"cytoskeletal activity"	"Pf05104"	"3895"	"ENSG00000126777"	"KTN1"	"B4DZ88; hsa:3895; Q13999; Q14707; Q15387; Q17RZ5; Q5GGW3; Q86UP2; Q86W57"	"Glucocorticoid receptor pathway; Nuclear receptors meta-pathway"	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RND2 GTPase cycle; RHOG GTPase cycle; RND3 GTPase cycle; RHO GTPases activate KTN1"	"11"	"1"	"535.7"	"470.2"	"581.8"	"495.8"	"569.7"	"578.8"	"660.1"	"774.0"	"2335.6"	"4719.7"	"7053.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BUQ8"	"Probable ATP-dependent RNA helicase DDX23 OS=Homo sapiens OX=9606 GN=DDX23 PE=1 SV=3"	"20"	"17"	"40"	"17"	"820"	"95.5"	"9.55"	"7145.56"	"64.34"	"16"	"16"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271"	"9416"	"ENSG00000174243"	"DDX23"	"B2R600; B4DH15; hsa:9416; O43188; Q9BUQ8"	""	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"2"	"0"	"1900.5"	"1630.0"	"1880.3"	"1625.3"	"1740.9"	"1772.7"	"2087.0"	"2385.5"	"3893.6"	"8606.9"	"15464.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51991"	"Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2"	"38"	"13"	"37"	"11"	"378"	"39.6"	"9.01"	"8097.34"	"64.09"	"10"	"12"	"RNA metabolism OR transcription;other metabolic processes;transport"	"nucleus;other cell component"	"transporter activity;nucleic acid binding activity"	"Pf00076"	"220988"	"ENSG00000170144"	"HNRNPA3"	"D3DPF4; hsa:220988; P51991; Q53RW7; Q6URK5"	""	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"2"	"0"	"1372.0"	"1498.5"	"1335.7"	"1198.4"	"1417.2"	"1215.4"	"1675.0"	"2043.8"	"2245.1"	"2952.9"	"4481.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92878"	"DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1"	"16"	"18"	"32"	"17"	"1312"	"153.8"	"6.89"	"4593.59"	"63.81"	"13"	"18"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04423, Pf13476, Pf13558"	"10111"	"ENSG00000113522"	"RAD50"	"B9EGF5; hsa:10111; O43254; Q6GMT7; Q6P5X3; Q92878; Q9UP86"	"miRNA regulation of DNA damage response; Homologous recombination; DDX1 as a regulatory component of the Drosha microprocessor; ATM signaling in development and disease ; Breast cancer pathway; Joubert syndrome; DNA repair pathways, full network; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; DNA damage response"	"Sensing of DNA Double Strand Breaks; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Resolution of D-loop Structures through Holliday Junction Intermediates; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; Meiotic recombination; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; DNA Damage/Telomere Stress Induced Senescence; Nonhomologous End-Joining (NHEJ); HDR through MMEJ (alt-NHEJ)"	"29"	"1"	"974.0"	"868.4"	"1039.0"	"872.8"	"1064.4"	"1007.2"	"1221.0"	"1549.4"	"3085.8"	"6753.6"	"11753.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BSJ8"	"Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1"	"18"	"13"	"28"	"13"	"1104"	"122.8"	"5.83"	"4948.17"	"63.80"	"9"	"12"	"cell organization and biogenesis;transport"	"plasma membrane;other membranes;ER/Golgi"	"transporter activity;other molecular function"	"Pf00168, Pf17047"	"23344"	"ENSG00000139641"	"ESYT1"	"A0FGR7; A8K2S2; hsa:23344; O94848; Q6PJN4; Q9BSJ8; Q9H6J1; Q9H6W2; Q9Y416"	""	"RHOG GTPase cycle; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOD GTPase cycle; Glycosphingolipid metabolism; RHOF GTPase cycle"	"7"	"0"	"295.3"	"275.8"	"437.2"	"427.7"	"636.2"	"785.8"	"1167.9"	"1846.3"	"3181.2"	"4486.9"	"6029.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46940"	"Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1"	"12"	"17"	"32"	"14"	"1657"	"189.1"	"6.48"	"6337.39"	"63.68"	"15"	"15"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00307, Pf00612, Pf00616, Pf03836"	"8826"	"ENSG00000140575"	"IQGAP1"	"A7MBM3; hsa:8826; P46940"	"VEGFA-VEGFR2 signaling; Ebola virus infection in host; Ciliary landscape; EGF/EGFR signaling pathway; Regulation of actin cytoskeleton; G13 signaling pathway"	"Signaling by BRAF and RAF1 fusions; RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RHO GTPases activate IQGAPs; RAC2 GTPase cycle; RHOV GTPase cycle; Neutrophil degranulation; RHOU GTPase cycle; Nephrin family interactions; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants"	"25"	"3"	"484.6"	"436.6"	"604.6"	"480.2"	"554.5"	"562.8"	"672.6"	"997.3"	"3978.9"	"7736.9"	"8491.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94906"	"Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1"	"24"	"18"	"32"	"18"	"941"	"106.9"	"8.25"	"5057.33"	"62.96"	"14"	"16"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf06424, Pf13181"	"24148"	"ENSG00000101161"	"PRPF6"	"B2RAR5; B3KMC6; hsa:24148; O94906; O95109; Q5VXS5; Q9H3Z1; Q9H4T9; Q9H4U8; Q9NTE6"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"3"	"0"	"1360.9"	"1180.9"	"1460.0"	"1234.5"	"1408.1"	"1267.1"	"1609.7"	"1861.8"	"3361.2"	"6769.6"	"10039.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06733"	"Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2"	"31"	"13"	"26"	"13"	"434"	"47.1"	"7.39"	"5099.92"	"62.57"	"9"	"13"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00113, Pf03952"	"2023"	"ENSG00000074800"	"ENO1"	"B2RD59; hsa:2023; P06733; P22712; Q16704; Q4TUS4; Q53FT9; Q53HR3; Q658M5; Q6GMP2; Q71V37; Q7Z3V6; Q8WU71; Q96GV1; Q9BT62; Q9UCH6; Q9UM55"	"Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Aerobic glycolysis; IL-18 signaling pathway; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"Glycolysis; Gluconeogenesis; Manipulation of host energy metabolism"	"9"	"0"	"402.2"	"359.5"	"483.0"	"464.0"	"453.4"	"415.9"	"520.8"	"825.2"	"3364.6"	"9514.8"	"17111.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P33992"	"DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5"	"22"	"14"	"33"	"14"	"734"	"82.2"	"8.37"	"6066.30"	"62.30"	"13"	"13"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf14551, Pf17207, Pf17855"	"4174"	"ENSG00000100297"	"MCM5"	"hsa:4174; O60785; P33992; Q14578; Q9BTJ4; Q9BWL8"	"Cell cycle; Ciliary landscape; G1 to S cell cycle control; DNA replication"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"10"	"0"	"947.2"	"975.5"	"1143.5"	"1045.8"	"1103.9"	"987.0"	"1301.4"	"1641.2"	"2941.7"	"6072.8"	"8199.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92804"	"TATA-binding protein-associated factor 2N OS=Homo sapiens OX=9606 GN=TAF15 PE=1 SV=1"	"22"	"8"	"22"	"5"	"592"	"61.8"	"8.02"	"2078.92"	"61.72"	"5"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00641"	"8148"	"ENSG00000270647; ENSG00000276833"	"TAF15"	"B2R837; hsa:8148; Q86X94; Q92751; Q92804"	"17q12 copy number variation syndrome"	"Regulation of TP53 Activity through Phosphorylation; RNA Polymerase II Pre-transcription Events; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation"	"10"	"0"	"534.3"	"490.9"	"571.7"	"450.5"	"478.3"	"459.0"	"638.9"	"739.4"	"1112.4"	"1474.1"	"2468.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NR30"	"Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5"	"20"	"12"	"29"	"11"	"783"	"87.3"	"9.28"	"6530.36"	"61.70"	"12"	"11"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf08152"	"9188"	"ENSG00000165732"	"DDX21"	"B2RDL0; hsa:9188; Q13436; Q5VX41; Q68D35; Q9NR30"	"10q11.21q11.23 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression; Major pathway of rRNA processing in the nucleolus and cytosol"	"3"	"1"	"716.2"	"598.4"	"739.1"	"633.7"	"713.4"	"738.5"	"847.8"	"1083.5"	"2457.2"	"4331.8"	"6875.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14204"	"Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5"	"5"	"18"	"31"	"18"	"4646"	"532.1"	"6.40"	"5160.22"	"61.33"	"14"	"17"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03028, Pf08385, Pf08393, Pf12774, Pf12775, Pf12777, Pf12780, Pf12781, Pf17852, Pf18198, Pf18199"	"1778"	"ENSG00000197102"	"DYNC1H1"	"B0I1R0; hsa:1778; Q14204; Q6DKQ7; Q8WU28; Q92814; Q9Y4G5"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein; PAFAH1B1 copy number variation"	"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Neutrophil degranulation; HCMV Early Events; Separation of Sister Chromatids; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; Recruitment of NuMA to mitotic centrosomes; RHO GTPases Activate Formins; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Aggrephagy; EML4 and NUDC in mitotic spindle formation; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"23"	"0"	"471.1"	"445.1"	"495.2"	"437.6"	"536.8"	"521.3"	"572.4"	"726.8"	"1545.2"	"4201.3"	"6381.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N1F7"	"Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2"	"20"	"16"	"35"	"16"	"819"	"93.4"	"5.72"	"6062.68"	"60.69"	"14"	"15"	"cell organization and biogenesis;other metabolic processes;transport;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus"	"other molecular function"	"Pf04097"	"9688"	"ENSG00000102900"	"NUP93"	"B3KPQ8; hsa:9688; Q14705; Q8N1F7"	""	"Regulation of HSF1-mediated heat shock response; Transport of Mature mRNA derived from an Intron-Containing Transcript; HCMV Late Events; HCMV Early Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Postmitotic nuclear pore complex (NPC) reformation"	"29"	"0"	"1173.0"	"1078.5"	"1292.8"	"1096.9"	"1228.1"	"1246.8"	"1391.6"	"1828.5"	"3203.6"	"5352.0"	"7340.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H6T3"	"RNA polymerase II-associated protein 3 OS=Homo sapiens OX=9606 GN=RPAP3 PE=1 SV=2"	"26"	"16"	"33"	"16"	"665"	"75.7"	"6.84"	"6729.93"	"60.69"	"14"	"15"	"other biological processes"	"cytosol;other cell component"	""	"Pf00515, Pf13176, Pf13181, Pf13877"	"79657"	"ENSG00000005175"	"RPAP3"	"B4DRW9; hsa:79657; Q6PHR5; Q9H6T3"	""	""	"0"	"0"	"468.2"	"435.1"	"513.1"	"447.6"	"554.6"	"528.0"	"606.4"	"890.4"	"4123.1"	"8878.2"	"10797.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2W1"	"Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2"	"21"	"19"	"38"	"18"	"955"	"108.6"	"10.15"	"7818.20"	"60.49"	"19"	"15"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf15440"	"9967"	"ENSG00000054118"	"THRAP3"	"D3DPS5; hsa:9967; Q5VTK6; Q9Y2W1"	"Interactome of polycomb repressive complex 2 (PRC2)"	"PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation"	"3"	"1"	"2773.9"	"2430.6"	"2733.7"	"2418.7"	"2595.2"	"2663.0"	"3104.2"	"3448.0"	"4629.7"	"8974.8"	"16337.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P26358"	"DNA (cytosine-5)-methyltransferase 1 OS=Homo sapiens OX=9606 GN=DNMT1 PE=1 SV=2"	"12"	"13"	"27"	"13"	"1616"	"183.1"	"7.75"	"4790.58"	"60.49"	"10"	"13"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00145, Pf01426, Pf02008, Pf06464, Pf12047"	"1786"	"ENSG00000130816"	"DNMT1"	"A0AV63; B7ZLW6; hsa:1786; P26358; Q9UHG5; Q9ULA2; Q9UMZ6"	"Trans-sulfuration pathway; One-carbon metabolism; Retinoblastoma gene in cancer; Hematopoietic stem cell gene regulation by GABP alpha/beta complex; MTHFR deficiency"	"SUMOylation of DNA methylation proteins; NoRC negatively regulates rRNA expression; PRC2 methylates histones and DNA; Defective pyroptosis; DNA methylation"	"10"	"0"	"1195.4"	"945.2"	"1291.0"	"1081.9"	"1165.7"	"1272.9"	"1508.6"	"1733.7"	"2866.4"	"4013.2"	"4658.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99832"	"T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2"	"31"	"12"	"22"	"12"	"543"	"59.3"	"7.65"	"3072.84"	"60.41"	"6"	"11"	"protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00118"	"10574"	"ENSG00000135624"	"CCT7"	"A8K7E6; A8MWI8; B7WNW9; B7Z4T9; B7Z4Z7; hsa:10574; O14871; Q6FI26; Q99832"	"VEGFA-VEGFR2 signaling; 16p11.2 proximal deletion syndrome"	"Formation of tubulin folding intermediates by CCT/TriC; RHOBTB1 GTPase cycle; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; RHOBTB2 GTPase cycle; Folding of actin by CCT/TriC"	"9"	"0"	"289.0"	"293.5"	"354.3"	"292.5"	"312.6"	"323.9"	"412.2"	"574.6"	"1265.6"	"5120.8"	"12049.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31942"	"Heterogeneous nuclear ribonucleoprotein H3 OS=Homo sapiens OX=9606 GN=HNRNPH3 PE=1 SV=2"	"29"	"10"	"26"	"9"	"346"	"36.9"	"6.87"	"3866.47"	"60.35"	"6"	"10"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf00076"	"3189"	"ENSG00000096746"	"HNRNPH3"	"A8K682; B3KRE1; hsa:3189; P31942; Q9BSX1; Q9NP53; Q9NP96; Q9NPA7; Q9NPI4; Q9UFU4; Q9Y4J5"	""	""	"0"	"0"	"675.2"	"734.8"	"738.6"	"560.1"	"689.6"	"683.5"	"835.8"	"1074.5"	"1617.9"	"2347.3"	"3448.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P78347"	"General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2"	"20"	"14"	"30"	"14"	"998"	"112.3"	"6.39"	"7894.76"	"60.30"	"13"	"12"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02946"	"2969"	"ENSG00000263001"	"GTF2I"	"hsa:2969; O14743; O15359; O43546; O43588; O43589; P78347; Q75M85; Q75M86; Q75M87; Q75M88; Q86U51; Q9BSZ4"	"B cell receptor signaling pathway; 7q11.23 copy number variation syndrome; Genetic causes of porto-sinusoidal vascular disease"	""	"3"	"0"	"921.9"	"880.6"	"957.1"	"806.7"	"945.7"	"921.1"	"1137.3"	"1552.6"	"3011.9"	"6408.0"	"9896.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BT78"	"COP9 signalosome complex subunit 4 OS=Homo sapiens OX=9606 GN=COPS4 PE=1 SV=1"	"38"	"12"	"26"	"12"	"406"	"46.2"	"5.83"	"4560.49"	"60.22"	"8"	"12"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf01399, Pf18420"	"51138"	"ENSG00000138663"	"COPS4"	"B3KN88; B3KST5; hsa:51138; Q561W7; Q9BT78; Q9NW31; Q9Y677"	"Ciliary landscape"	"Cargo recognition for clathrin-mediated endocytosis; Neddylation; Formation of TC-NER Pre-Incision Complex; DNA Damage Recognition in GG-NER; RHOBTB1 GTPase cycle"	"6"	"0"	"323.1"	"281.9"	"389.3"	"338.7"	"400.8"	"382.8"	"509.1"	"765.9"	"1887.4"	"5603.3"	"10354.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14498"	"RNA-binding protein 39 OS=Homo sapiens OX=9606 GN=RBM39 PE=1 SV=2"	"25"	"12"	"31"	"10"	"530"	"59.3"	"10.10"	"4508.88"	"60.13"	"10"	"11"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00076, Pf15519"	"9584"	"ENSG00000131051"	"RBM39"	"A2RRD3; A5D8W2; B0BLV3; E1P5S0; E1P5S1; hsa:9584; Q14498; Q14499"	"VEGFA-VEGFR2 signaling; mRNA processing"	"mRNA Splicing - Major Pathway"	"3"	"1"	"1145.9"	"1095.2"	"1146.6"	"936.8"	"1093.9"	"1050.9"	"1271.9"	"1562.4"	"2718.0"	"4772.5"	"6253.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15365"	"Poly(rC)-binding protein 1 OS=Homo sapiens OX=9606 GN=PCBP1 PE=1 SV=2"	"37"	"9"	"21"	"4"	"356"	"37.5"	"7.09"	"3390.25"	"59.97"	"6"	"9"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013"	"5093"	"ENSG00000169564"	"PCBP1"	"hsa:5093; Q13157; Q14975; Q15365"	"Ferroptosis"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"3"	"0"	"168.3"	"194.6"	"238.6"	"192.8"	"201.6"	"136.7"	"250.6"	"400.6"	"680.8"	"1206.1"	"1669.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q29RF7"	"Sister chromatid cohesion protein PDS5 homolog A OS=Homo sapiens OX=9606 GN=PDS5A PE=1 SV=1"	"10"	"13"	"25"	"11"	"1337"	"150.7"	"7.91"	"4736.00"	"59.88"	"10"	"13"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	""	"Pf20168"	"23244"	"ENSG00000121892"	"PDS5A"	"hsa:23244; Q29RF7; Q2TTR5; Q68DF7; Q8N7J4; Q8NG14; Q9Y4D4"	"Cohesin complex - Cornelia de Lange syndrome; 10q22q23 copy number variation"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"6"	"1"	"767.5"	"636.1"	"872.5"	"752.1"	"798.0"	"845.3"	"952.5"	"1065.6"	"2864.2"	"4347.8"	"5332.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75131"	"Copine-3 OS=Homo sapiens OX=9606 GN=CPNE3 PE=1 SV=1"	"26"	"11"	"22"	"11"	"537"	"60.1"	"5.85"	"2118.38"	"59.75"	"5"	"11"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;kinase activity;other molecular function"	"Pf00168, Pf07002"	"8895"	"ENSG00000085719"	"CPNE3"	"A8KA47; hsa:8895; O75131; Q8IYA1"	""	"Neutrophil degranulation; Glycerophospholipid biosynthesis"	"2"	"0"	"204.4"	"230.2"	"299.6"	"232.6"	"250.5"	"244.7"	"314.9"	"426.6"	"862.9"	"2180.8"	"12372.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P26368"	"Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4"	"27"	"10"	"23"	"10"	"475"	"53.5"	"9.09"	"3592.39"	"58.93"	"5"	"10"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"11338"	"ENSG00000063244"	"U2AF2"	"hsa:11338; P26368; Q96HC5"	"mRNA processing; Warburg effect modulated by deubiquitinating enzymes and their substrates"	"mRNA Splicing - Major Pathway; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript"	"6"	"0"	"254.2"	"265.1"	"290.5"	"248.9"	"295.4"	"259.5"	"345.0"	"479.3"	"2667.0"	"6941.0"	"9875.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35637"	"RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1"	"24"	"11"	"25"	"8"	"526"	"53.4"	"9.36"	"4531.01"	"58.76"	"7"	"9"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00641"	"2521"	"ENSG00000089280"	"FUS"	"hsa:2521; P35637; Q9H4A8"	"MECP2 and associated Rett syndrome; mRNA processing"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"4"	"3"	"1970.9"	"1878.0"	"1689.2"	"1516.3"	"1622.2"	"1711.3"	"2092.3"	"2338.7"	"3107.5"	"4583.6"	"7122.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55196"	"Afadin OS=Homo sapiens OX=9606 GN=AFDN PE=1 SV=3"	"9"	"14"	"30"	"14"	"1824"	"206.7"	"6.47"	"5190.85"	"58.69"	"12"	"14"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00498, Pf00595, Pf00788, Pf01843"	"4301"	"ENSG00000130396"	"AFDN"	"hsa:4301; O75087; O75088; O75089; P55196; Q59FP0; Q5TIG6; Q5TIG7; Q9NSN7; Q9NU92"	"VEGFA-VEGFR2 signaling; Ras signaling; 1q21.1 copy number variation syndrome"	""	"3"	"0"	"963.1"	"864.8"	"953.1"	"802.6"	"925.3"	"962.7"	"1132.1"	"1521.7"	"5324.4"	"6749.0"	"6629.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92499"	"ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2"	"24"	"13"	"29"	"13"	"740"	"82.4"	"7.23"	"5990.26"	"58.51"	"12"	"13"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf00622"	"1653"	"ENSG00000079785"	"DDX1"	"B4DME8; B4DPN6; hsa:1653; Q92499"	"DDX1 as a regulatory component of the Drosha microprocessor; mRNA processing"	"tRNA processing in the nucleus"	"3"	"0"	"1150.5"	"943.1"	"1140.9"	"1055.9"	"1136.2"	"1003.0"	"1333.8"	"1593.8"	"2152.7"	"3760.0"	"6250.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11908"	"Ribose-phosphate pyrophosphokinase 2 OS=Homo sapiens OX=9606 GN=PRPS2 PE=1 SV=2"	"43"	"12"	"25"	"4"	"318"	"34.7"	"6.61"	"4771.69"	"58.46"	"9"	"11"	"other metabolic processes;other biological processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf13793, Pf14572"	"5634"	"ENSG00000101911"	"PRPS2"	"hsa:5634; P11908; Q0VDH9; Q0VDI0; Q15245; Q2TAK7"	""	"5-Phosphoribose 1-diphosphate biosynthesis"	"1"	"0"	"244.5"	"219.5"	"267.4"	"231.3"	"256.7"	"293.0"	"370.0"	"615.4"	"1218.3"	"1849.0"	"2650.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62805"	"Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2"	"60"	"9"	"31"	"9"	"103"	"11.4"	"11.36"	"5673.32"	"58.33"	"9"	"9"	"cell organization and biogenesis;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf15511"	"121504; 554313; 8294; 8359; 8360; 8361; 8362; 8363; 8364; 8365; 8366; 8367; 8368; 8370"	"ENSG00000158406; ENSG00000197061; ENSG00000197238; ENSG00000197837; ENSG00000270276; ENSG00000270882; ENSG00000273542; ENSG00000274618; ENSG00000275126; ENSG00000276180; ENSG00000276966; ENSG00000277157; ENSG00000278637; ENSG00000278705"	"H4C1; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9"	"A2VCL0; hsa:121504; hsa:554313; hsa:8294; hsa:8359; hsa:8360; hsa:8361; hsa:8362; hsa:8363; hsa:8364; hsa:8365; hsa:8366; hsa:8367; hsa:8368; hsa:8370; P02304; P02305; P62805; Q6DRA9; Q6FGB8; Q6NWP7"	"Gastric cancer network 1; Histone modifications; 22q11.2 copy number variation syndrome; Male infertility; Type II interferon signaling"	"Meiotic synapsis; Estrogen-dependent gene expression; HDACs deacetylate histones; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; Meiotic recombination; SUMOylation of chromatin organization proteins; HCMV Late Events; Amyloid fiber formation; RUNX1 regulates transcription of genes involved in differentiation of HSCs; HCMV Early Events; Transcriptional regulation by small RNAs; Deposition of new CENPA-containing nucleosomes at the centromere; B-WICH complex positively regulates rRNA expression; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Formation of the beta-catenin:TCF transactivating complex; Oxidative Stress Induced Senescence; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Pre-NOTCH Transcription and Translation; Senescence-Associated Secretory Phenotype (SASP); RMTs methylate histone arginines; HDMs demethylate histones; PKMTs methylate histone lysines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; HATs acetylate histones; RNA Polymerase I Promoter Escape; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Packaging Of Telomere Ends; Condensation of Prophase Chromosomes; DNA Damage/Telomere Stress Induced Senescence; DNA methylation; Nonhomologous End-Joining (NHEJ); RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis"	"50"	"0"	"1029.0"	"877.2"	"912.0"	"887.7"	"890.5"	"1103.7"	"1195.4"	"1436.5"	"2485.5"	"3503.9"	"5399.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P43243"	"Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2"	"23"	"21"	"36"	"21"	"847"	"94.6"	"6.25"	"6775.77"	"58.27"	"18"	"15"	"stress response;developmental processes;other biological processes"	"other membranes;nucleus"	"nucleic acid binding activity;other molecular function"	""	"9782"	"ENSG00000015479"	"MATR3"	"B7ZAV5; D3DQC3; hsa:9782; P43243; Q9UHW0; Q9UQ27"	""	""	"0"	"0"	"2480.5"	"2310.5"	"2559.6"	"2270.8"	"2346.7"	"2180.5"	"2958.8"	"4001.3"	"4988.3"	"7765.9"	"10988.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P38159"	"RNA-binding motif protein, X chromosome OS=Homo sapiens OX=9606 GN=RBMX PE=1 SV=3"	"32"	"10"	"31"	"4"	"391"	"42.3"	"10.05"	"5993.05"	"57.64"	"9"	"10"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08081"	"27316"	"ENSG00000147274"	"RBMX"	"B4E3U4; D3DWH0; E9PG86; hsa:27316; P38159; Q5JQ67; Q8N8Y7; Q969R3"	"mRNA processing"	"mRNA Splicing - Major Pathway; RND2 GTPase cycle; RND3 GTPase cycle; RND1 GTPase cycle; Processing of Capped Intron-Containing Pre-mRNA; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle"	"8"	"6"	"3127.4"	"3542.3"	"3177.6"	"2772.8"	"2984.7"	"2894.1"	"3693.8"	"4212.9"	"4400.8"	"6432.7"	"10410.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P54886"	"Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2"	"26"	"16"	"28"	"16"	"795"	"87.2"	"7.12"	"4265.98"	"57.60"	"11"	"16"	"other metabolic processes"	"other membranes;mitochondrion"	"kinase activity;other molecular function"	"Pf00171, Pf00696"	"5832"	"ENSG00000059573"	"ALDH18A1"	"B2R5Q4; B7Z350; B7Z5X8; B7ZLP1; D3DR44; hsa:5832; O95952; P54886; Q3KQU2; Q5T566; Q5T567; Q9UM72"	"Amino acid metabolism"	""	"1"	"0"	"706.4"	"720.1"	"766.0"	"633.9"	"777.0"	"718.9"	"901.0"	"1218.9"	"2162.5"	"3942.9"	"5986.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99615"	"DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2"	"43"	"18"	"37"	"18"	"494"	"56.4"	"6.96"	"7083.86"	"57.11"	"15"	"17"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00226, Pf13181, Pf13414, Pf13432"	"7266"	"ENSG00000168259"	"DNAJC7"	"hsa:7266; Q7Z784; Q99615"	"Constitutive androstane receptor pathway; Pregnane X receptor pathway; Nuclear receptors meta-pathway"	"Regulation of HSF1-mediated heat shock response"	"4"	"0"	"1073.0"	"986.1"	"1160.8"	"1005.7"	"1204.0"	"1118.8"	"1326.9"	"1773.4"	"4481.5"	"8732.0"	"12913.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q02790"	"Peptidyl-prolyl cis-trans isomerase FKBP4 OS=Homo sapiens OX=9606 GN=FKBP4 PE=1 SV=3"	"31"	"10"	"19"	"10"	"459"	"51.8"	"5.43"	"3213.97"	"56.95"	"4"	"10"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00254, Pf00515"	"2288"	"ENSG00000004478"	"FKBP4"	"D3DUQ1; hsa:2288; Q02790; Q9UCP1; Q9UCV7"	"Androgen receptor signaling pathway"	"Estrogen-dependent gene expression; Potential therapeutics for SARS; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Attenuation phase"	"6"	"0"	"204.3"	"230.9"	"251.3"	"215.2"	"242.1"	"235.2"	"287.5"	"335.7"	"625.4"	"2462.3"	"9772.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95747"	"Serine/threonine-protein kinase OSR1 OS=Homo sapiens OX=9606 GN=OXSR1 PE=1 SV=1"	"27"	"10"	"25"	"9"	"527"	"58.0"	"6.43"	"4035.21"	"56.76"	"5"	"9"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf12202"	"9943"	"ENSG00000172939"	"OXSR1"	"hsa:9943; O95747; Q3LR53; Q7Z501; Q9UPQ1"	""	""	"0"	"2"	"236.4"	"228.7"	"266.2"	"238.0"	"242.6"	"245.9"	"317.7"	"516.6"	"2249.7"	"5368.5"	"7482.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BVJ6"	"U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1"	"21"	"14"	"31"	"10"	"771"	"87.9"	"7.87"	"6583.67"	"56.72"	"13"	"13"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf04615"	"10813"	"ENSG00000156697"	"UTP14A"	"A8K7A3; A8MVQ1; B4DQ08; E9PEL7; hsa:10813; Q5JYF1; Q9BVJ6"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"5"	"1495.2"	"1212.3"	"1659.2"	"1453.6"	"1593.4"	"1570.5"	"1805.2"	"2076.9"	"2886.8"	"3576.1"	"3518.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11940"	"Polyadenylate-binding protein 1 OS=Homo sapiens OX=9606 GN=PABPC1 PE=1 SV=2"	"27"	"15"	"33"	"12"	"636"	"70.6"	"9.50"	"5691.26"	"56.12"	"14"	"14"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf00658"	"26986"	"ENSG00000070756"	"PABPC1"	"hsa:26986; P11940; Q15097; Q93004"	"Translation factors; Endoderm differentiation; VEGFA-VEGFR2 signaling; Acute viral myocarditis"	"AUF1 (hnRNP D0) binds and destabilizes mRNA; Regulation of expression of SLITs and ROBOs; Deadenylation of mRNA; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"11"	"2"	"1887.1"	"1735.7"	"1954.1"	"1692.8"	"1918.9"	"1925.7"	"2238.7"	"2568.2"	"3158.4"	"4678.3"	"7138.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P12081"	"Histidine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=HARS1 PE=1 SV=2"	"35"	"18"	"31"	"14"	"509"	"57.4"	"5.88"	"5062.99"	"55.73"	"12"	"16"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00458, Pf03129, Pf13393"	"3035"	"ENSG00000170445"	"HARS1"	"B4DHQ1; B4DY73; D6REN6; hsa:3035; J3KNE5; P12081"	"Allograft rejection"	"Cytosolic tRNA aminoacylation"	"2"	"3"	"514.4"	"475.4"	"540.2"	"470.2"	"539.1"	"614.1"	"740.6"	"1422.1"	"4466.2"	"11134.7"	"19167.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UHX1"	"Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1"	"30"	"16"	"31"	"16"	"559"	"59.8"	"5.29"	"5210.89"	"55.69"	"13"	"12"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"22827"	"ENSG00000179950; ENSG00000274081"	"PUF60"	"A8K8K8; hsa:22827; Q969E7; Q96D94; Q96H63; Q99628; Q9NZA0; Q9UHX1; Q9UJY7"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"1206.6"	"1090.1"	"1195.6"	"1109.2"	"1196.8"	"1098.2"	"1397.8"	"1656.4"	"3645.2"	"9330.1"	"15733.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P18754"	"Regulator of chromosome condensation OS=Homo sapiens OX=9606 GN=RCC1 PE=1 SV=1"	"28"	"13"	"26"	"13"	"421"	"44.9"	"7.52"	"4723.88"	"55.66"	"10"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00415"	"1104"	"ENSG00000180198"	"RCC1"	"hsa:1104; P18754; Q16269; Q6NT97"	"22q11.2 copy number variation syndrome"	"Rev-mediated nuclear export of HIV RNA; Nuclear import of Rev protein; Postmitotic nuclear pore complex (NPC) reformation"	"4"	"0"	"1041.6"	"926.5"	"1095.5"	"964.4"	"939.4"	"1046.4"	"1236.1"	"1456.6"	"2391.4"	"3637.4"	"4301.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P29401"	"Transketolase OS=Homo sapiens OX=9606 GN=TKT PE=1 SV=3"	"19"	"11"	"21"	"11"	"623"	"67.8"	"7.66"	"3367.97"	"55.63"	"6"	"11"	"other metabolic processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle"	"other molecular function"	"Pf00456, Pf02779, Pf02780"	"7086"	"ENSG00000163931"	"TKT"	"A8K089; B4DE31; E7EPA7; hsa:7086; P29401; Q8TBA3; Q96HH3"	"Pentose phosphate metabolism; VEGFA-VEGFR2 signaling; Metabolic reprogramming in colon cancer; Thiamine metabolic pathways"	"NFE2L2 regulates pentose phosphate pathway genes; Pentose phosphate pathway; Insulin effects increased synthesis of Xylulose-5-Phosphate"	"7"	"0"	"285.8"	"280.9"	"352.5"	"325.0"	"337.2"	"354.3"	"438.7"	"592.8"	"1588.6"	"5012.9"	"10017.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25705"	"ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1"	"24"	"10"	"28"	"10"	"553"	"59.7"	"9.13"	"5953.68"	"55.48"	"8"	"10"	"other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;transporter activity;other molecular function"	"Pf00006, Pf00306, Pf02874"	"498"	"ENSG00000152234"	"ATP5F1A"	"A8K092; B4DY56; hsa:498; K7ENP3; P25705; Q53XX6; Q8IXV2; Q96FB4; Q96HW2; Q96IR6; Q9BTV8"	"Electron transport chain: OXPHOS system in mitochondria; 7q11.23 copy number variation syndrome; Oxidative phosphorylation"	"Mitochondrial protein import; Cristae formation; Formation of ATP by chemiosmotic coupling"	"6"	"0"	"553.5"	"581.7"	"639.2"	"592.3"	"605.1"	"638.3"	"753.8"	"1008.7"	"2133.9"	"5227.8"	"7822.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35221"	"Catenin alpha-1 OS=Homo sapiens OX=9606 GN=CTNNA1 PE=1 SV=1"	"21"	"16"	"29"	"16"	"906"	"100.0"	"6.29"	"5315.37"	"55.26"	"14"	"15"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01044"	"1495"	"ENSG00000044115"	"CTNNA1"	"hsa:1495; P35221; Q12795; Q8N1C0"	"Arrhythmogenic right ventricular cardiomyopathy; Apoptosis-related network due to altered Notch3 in ovarian cancer; VEGFA-VEGFR2 signaling; White fat cell differentiation; Endometrial cancer; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-Merlin signaling dysregulation; Pleural mesothelioma"	"RHO GTPases activate IQGAPs; Myogenesis; Adherens junctions interactions; VEGFR2 mediated vascular permeability; Regulation of CDH11 function; Regulation of CDH19 Expression and Function; CDH11 homotypic and heterotypic interactions"	"15"	"0"	"434.1"	"409.3"	"545.0"	"432.8"	"512.3"	"501.1"	"538.3"	"745.8"	"3000.2"	"7047.0"	"8611.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92917"	"G-patch domain and KOW motifs-containing protein OS=Homo sapiens OX=9606 GN=GPKOW PE=1 SV=2"	"29"	"11"	"27"	"11"	"476"	"52.2"	"6.15"	"5752.82"	"55.13"	"9"	"10"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00467, Pf12656"	"27238"	"ENSG00000068394"	"GPKOW"	"hsa:27238; Q59EK5; Q92917; Q9BQA8"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"516.0"	"488.4"	"547.0"	"501.7"	"542.3"	"567.4"	"722.1"	"1064.7"	"3580.8"	"6429.7"	"8773.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60716"	"Catenin delta-1 OS=Homo sapiens OX=9606 GN=CTNND1 PE=1 SV=1"	"26"	"18"	"31"	"18"	"968"	"108.1"	"6.23"	"6971.62"	"55.02"	"15"	"14"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00514"	"1500"	"ENSG00000198561"	"CTNND1"	"A8K939; hsa:1500; O15088; O60713; O60714; O60715; O60716; O60935; Q6DHZ7; Q6RBX8; Q9UP71; Q9UP72; Q9UP73"	"VEGFA-VEGFR2 signaling; Wnt signaling pathway and pluripotency"	"VEGFR2 mediated vascular permeability; Adherens junctions interactions; InlA-mediated entry of Listeria monocytogenes into host cells; Regulation of CDH11 function; Regulation of CDH19 Expression and Function; CDH11 homotypic and heterotypic interactions"	"8"	"0"	"1140.0"	"1154.1"	"1106.3"	"1005.0"	"1246.3"	"1171.4"	"1319.1"	"1587.5"	"3027.0"	"5303.5"	"7387.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EE3"	"Nucleoporin SEH1 OS=Homo sapiens OX=9606 GN=SEH1L PE=1 SV=3"	"36"	"8"	"21"	"8"	"360"	"39.6"	"8.09"	"4206.93"	"54.63"	"6"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;other biological processes"	"other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00400"	"81929"	"ENSG00000085415"	"SEH1L"	"A8K5B1; hsa:81929; Q8NFU6; Q96EE3; Q96MH3; Q9C069"	""	"Amino acids regulate mTORC1"	"1"	"0"	"354.9"	"401.0"	"363.6"	"339.5"	"400.4"	"388.4"	"460.8"	"607.0"	"1020.9"	"1977.8"	"3402.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96AC1"	"Fermitin family homolog 2 OS=Homo sapiens OX=9606 GN=FERMT2 PE=1 SV=1"	"25"	"14"	"28"	"14"	"680"	"77.8"	"6.70"	"5235.74"	"54.56"	"10"	"12"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00169, Pf00373, Pf18124"	"10979"	"ENSG00000073712"	"FERMT2"	"B5TJY2; hsa:10979; Q14840; Q86TY7; Q96AC1"	""	"RAC1 GTPase cycle; RAC3 GTPase cycle; Cell-extracellular matrix interactions"	"3"	"0"	"303.2"	"243.0"	"379.9"	"320.5"	"382.0"	"412.3"	"591.8"	"1308.5"	"3572.8"	"7605.6"	"11873.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P98175"	"RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3"	"19"	"15"	"26"	"14"	"930"	"103.5"	"5.97"	"4034.27"	"54.52"	"11"	"13"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00641, Pf01585, Pf17780"	"8241"	"ENSG00000182872"	"RBM10"	"A0A0A0MR66; C4AM81; hsa:8241; P98175; Q14136; Q5JRR2; Q9BTE4; Q9BTX0; Q9NTB1"	""	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"2"	"1"	"1014.5"	"900.1"	"1056.9"	"905.3"	"1066.1"	"913.7"	"1122.8"	"1245.4"	"2003.4"	"3707.3"	"5207.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00159"	"Unconventional myosin-Ic OS=Homo sapiens OX=9606 GN=MYO1C PE=1 SV=4"	"16"	"13"	"30"	"12"	"1063"	"121.6"	"9.41"	"5561.94"	"54.25"	"11"	"13"	"cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00063, Pf00612, Pf06017"	"4641"	"ENSG00000197879"	"MYO1C"	"hsa:4641; O00159; Q4LE56; Q6NVJ7; Q86Y95"	"VEGFA-VEGFR2 signaling; Insulin signaling; 10q11.21q11.23 copy number variation syndrome"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Translocation of SLC2A4 (GLUT4) to the plasma membrane"	"8"	"1"	"468.2"	"424.7"	"509.6"	"435.3"	"499.1"	"549.2"	"802.0"	"1368.8"	"3830.7"	"4591.1"	"4942.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96P16"	"Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1"	"42"	"12"	"30"	"10"	"312"	"35.7"	"7.55"	"5623.69"	"54.21"	"11"	"11"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf04818, Pf16566"	"55197"	"ENSG00000141425"	"RPRD1A"	"A8KA42; B2RBA3; hsa:55197; Q7Z5G8; Q96FY9; Q96P16; Q9NVL4"	""	"RNA polymerase II transcribes snRNA genes"	"1"	"2"	"1648.3"	"1589.1"	"1647.9"	"1341.2"	"1596.4"	"1684.2"	"2130.9"	"2699.1"	"3531.5"	"5341.5"	"5978.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35527"	"Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3"	"27"	"13"	"26"	"12"	"623"	"62.0"	"5.24"	"4565.61"	"54.06"	"10"	"10"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton"	"cytoskeletal activity"	"Pf00038"	"3857"	"ENSG00000171403"	"KRT9"	"hsa:3857; O00109; P35527; Q0IJ47; Q14665"	""	"Formation of the cornified envelope"	"2"	"0"	"236.3"	"666.4"	"1889.6"	"261.5"	"2122.7"	"914.7"	"823.5"	"2620.0"	"3353.4"	"6600.4"	"2369.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBU9"	"Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1"	"19"	"8"	"21"	"8"	"619"	"70.1"	"8.51"	"3768.33"	"53.82"	"7"	"8"	"other metabolic processes;transport"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf02136, Pf03943, Pf09162"	"10482"	"ENSG00000162231"	"NXF1"	"B4E269; hsa:10482; Q99799; Q9UBU9; Q9UQL2"	"mRNA processing"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript"	"5"	"0"	"601.9"	"519.4"	"585.5"	"566.1"	"603.1"	"675.7"	"756.4"	"800.5"	"1081.8"	"1795.8"	"2868.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7L014"	"Probable ATP-dependent RNA helicase DDX46 OS=Homo sapiens OX=9606 GN=DDX46 PE=1 SV=2"	"16"	"14"	"28"	"14"	"1031"	"117.3"	"9.29"	"5380.10"	"53.76"	"13"	"13"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"other membranes;nucleus"	"other molecular function"	"Pf00270, Pf00271"	"9879"	"ENSG00000145833"	"DDX46"	"hsa:9879; O94894; Q7L014; Q96EI0; Q9Y658"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"904.5"	"824.2"	"857.3"	"737.5"	"885.4"	"869.9"	"1027.4"	"1285.2"	"3408.8"	"8892.2"	"13623.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P2J5"	"Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2"	"13"	"14"	"29"	"14"	"1176"	"134.4"	"7.30"	"4926.43"	"53.58"	"12"	"12"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00133, Pf08264"	"51520"	"ENSG00000133706"	"LARS1"	"A2RRR4; A7E266; B4DJ10; hsa:51520; Q2TU79; Q9NSE1; Q9P2J5"	""	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"2"	"0"	"588.5"	"516.2"	"616.5"	"540.8"	"610.5"	"613.9"	"703.0"	"864.2"	"1825.2"	"4691.1"	"7265.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14678"	"Small nuclear ribonucleoprotein-associated proteins B and B' OS=Homo sapiens OX=9606 GN=SNRPB PE=1 SV=2"	"22"	"8"	"24"	"8"	"240"	"24.6"	"11.19"	"2864.99"	"53.53"	"5"	"8"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01423"	"6628"	"ENSG00000125835"	"SNRPB"	"hsa:6628; P14678; Q15490; Q6IB35; Q9UIS5"	"mRNA processing"	"snRNP Assembly; RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway; SARS-CoV-2 modulates host translation machinery; mRNA Splicing - Minor Pathway; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"8"	"0"	"941.8"	"817.2"	"1118.5"	"870.7"	"902.5"	"834.7"	"1158.8"	"1627.9"	"2520.0"	"4013.6"	"6636.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11586"	"C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=3"	"19"	"15"	"27"	"15"	"935"	"101.5"	"7.30"	"4952.10"	"53.29"	"13"	"14"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"866.0"	"825.8"	"889.9"	"817.9"	"874.6"	"757.3"	"995.7"	"1384.6"	"2136.1"	"4115.9"	"6399.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P41252"	"Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2"	"13"	"13"	"30"	"13"	"1262"	"144.4"	"6.15"	"6131.11"	"53.26"	"11"	"12"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00133, Pf08264, Pf19302"	"3376"	"ENSG00000196305"	"IARS1"	"A8KAE9; hsa:3376; P41252; Q5TCD0; Q7Z3T4; Q9H588"	"Amino acid metabolism"	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"3"	"0"	"560.5"	"548.3"	"694.2"	"554.4"	"653.4"	"607.3"	"735.1"	"976.5"	"2353.4"	"6255.1"	"9913.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WUM0"	"Nuclear pore complex protein Nup133 OS=Homo sapiens OX=9606 GN=NUP133 PE=1 SV=2"	"16"	"17"	"34"	"17"	"1156"	"128.9"	"5.10"	"7497.73"	"53.20"	"16"	"15"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf03177"	"55746"	"ENSG00000069248"	"NUP133"	"B2RAZ8; hsa:55746; Q5T8N0; Q8WUM0; Q9H9W2; Q9NV71; Q9NVC4"	"Ciliary landscape"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; SUMOylation of DNA replication proteins; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Transport of Mature mRNA derived from an Intron-Containing Transcript; snRNP Assembly; SARS-CoV-2 activates/modulates innate and adaptive immune responses; HCMV Early Events; SUMOylation of DNA damage response and repair proteins; Regulation of HSF1-mediated heat shock response; HCMV Late Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; Postmitotic nuclear pore complex (NPC) reformation"	"36"	"0"	"1428.1"	"1375.9"	"1623.6"	"1281.8"	"1522.6"	"1436.8"	"1649.4"	"2285.1"	"3450.9"	"6117.4"	"9720.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16181"	"Septin-7 OS=Homo sapiens OX=9606 GN=SEPTIN7 PE=1 SV=2"	"30"	"11"	"26"	"10"	"437"	"50.6"	"8.63"	"6077.57"	"53.07"	"11"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00735"	"989"	"ENSG00000122545"	"SEPTIN7"	"hsa:989; Q16181; Q52M76; Q6NX50"	""	"MAPK6/MAPK4 signaling"	"1"	"0"	"485.9"	"380.0"	"665.6"	"499.8"	"599.7"	"531.5"	"654.8"	"866.4"	"1911.8"	"2796.9"	"3810.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55265"	"Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4"	"12"	"11"	"29"	"11"	"1226"	"136.0"	"8.65"	"5793.26"	"53.04"	"10"	"11"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00035, Pf02137, Pf02295"	"103"	"ENSG00000160710"	"ADAR"	"B1AQQ9; B1AQR0; D3DV76; hsa:103; O15223; O43859; O43860; P55265; Q9BYM3; Q9BYM4"	"Measles virus infection; Cytosolic DNA-sensing pathway"	"Interferon alpha/beta signaling; C6 deamination of adenosine; Formation of editosomes by ADAR proteins"	"5"	"0"	"1280.2"	"1144.0"	"1323.3"	"1154.9"	"1218.7"	"1228.6"	"1538.7"	"1778.9"	"2239.7"	"3446.9"	"5303.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07900"	"Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5"	"19"	"13"	"27"	"3"	"732"	"84.6"	"5.02"	"4151.35"	"52.84"	"10"	"13"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"non-structural extracellular;extracellular matrix;plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00183, Pf02518"	"3320"	"ENSG00000080824"	"HSP90AA1"	"A8K500; B3KPJ9; hsa:3320; P07900; Q2PP14; Q5CAQ6; Q5CAQ7; Q9BVQ5"	"Nucleotide-binding oligomerization domain (NOD) pathway; TNF-alpha signaling pathway; Corticotropin-releasing hormone signaling pathway; Aryl hydrocarbon receptor pathway; Ebstein-Barr virus LMP1 signaling; Aryl hydrocarbon receptor pathway; Constitutive androstane receptor pathway; Pregnane X receptor pathway; Glucocorticoid receptor pathway; Nuclear receptors meta-pathway; NRF2 pathway; VEGFA-VEGFR2 signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Th17 cell differentiation pathway"	"Neutrophil degranulation; Estrogen-dependent gene expression; Regulation of actin dynamics for phagocytic cup formation; Potential therapeutics for SARS; The role of GTSE1 in G2/M progression after G2 checkpoint; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Recruitment of NuMA to mitotic centrosomes; Aggrephagy; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Extra-nuclear estrogen signaling; vRNP Assembly; Regulation of necroptotic cell death; Interleukin-4 and Interleukin-13 signaling; Downregulation of ERBB2 signaling; Signaling by ERBB2 KD Mutants; Signaling by ERBB2 TMD/JMD mutants; Sema3A PAK dependent Axon repulsion; DDX58/IFIH1-mediated induction of interferon-alpha/beta; PIWI-interacting RNA (piRNA) biogenesis; VEGFR2 mediated vascular permeability; RHOBTB2 GTPase cycle; Chaperone Mediated Autophagy; HSF1 activation; Attenuation phase; eNOS activation; Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation; Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; Constitutive Signaling by EGFRvIII; Signaling by ERBB2 ECD mutants; Uptake and function of diphtheria toxin; Constitutive Signaling by Overexpressed ERBB2; Scavenging by Class F Receptors; Drug-mediated inhibition of ERBB2 signaling; Resistance of ERBB2 KD mutants to trastuzumab; Resistance of ERBB2 KD mutants to sapitinib; Resistance of ERBB2 KD mutants to tesevatinib; Resistance of ERBB2 KD mutants to neratinib; Resistance of ERBB2 KD mutants to osimertinib; Resistance of ERBB2 KD mutants to afatinib; Resistance of ERBB2 KD mutants to AEE788; Resistance of ERBB2 KD mutants to lapatinib; Drug resistance in ERBB2 TMD/JMD mutants"	"67"	"0"	"297.3"	"251.5"	"310.3"	"328.0"	"287.0"	"277.0"	"351.2"	"434.7"	"547.0"	"782.8"	"1169.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15075"	"Early endosome antigen 1 OS=Homo sapiens OX=9606 GN=EEA1 PE=1 SV=2"	"11"	"12"	"25"	"12"	"1411"	"162.4"	"5.68"	"5418.45"	"52.74"	"12"	"11"	"cell-cell signaling;cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01363"	"8411"	"ENSG00000102189"	"EEA1"	"hsa:8411; Q14221; Q15075"	"VEGFA-VEGFR2 signaling"	"Toll Like Receptor 9 (TLR9) Cascade"	"2"	"0"	"172.5"	"146.0"	"195.9"	"184.0"	"247.4"	"190.5"	"214.2"	"305.8"	"1382.5"	"2404.3"	"3877.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23921"	"Ribonucleoside-diphosphate reductase large subunit OS=Homo sapiens OX=9606 GN=RRM1 PE=1 SV=1"	"15"	"11"	"23"	"11"	"792"	"90.0"	"7.15"	"4891.24"	"52.66"	"9"	"10"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf00317, Pf02867, Pf03477"	"6240"	"ENSG00000167325"	"RRM1"	"hsa:6240; P23921; Q9UNN2"	"Fluoropyrimidine activity; Retinoblastoma gene in cancer; Pyrimidine metabolism"	"Interconversion of nucleotide di- and triphosphates"	"4"	"0"	"243.3"	"237.2"	"263.3"	"246.2"	"302.8"	"287.9"	"390.0"	"722.1"	"2434.4"	"5454.4"	"8603.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49959"	"Double-strand break repair protein MRE11 OS=Homo sapiens OX=9606 GN=MRE11 PE=1 SV=3"	"21"	"11"	"25"	"11"	"708"	"80.5"	"5.90"	"4939.34"	"52.39"	"9"	"11"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00149, Pf04152"	"4361"	"ENSG00000020922"	"MRE11"	"B3KTC7; hsa:4361; O43475; P49959"	"miRNA regulation of DNA damage response; Homologous recombination; DDX1 as a regulatory component of the Drosha microprocessor; ATM signaling in development and disease ; Breast cancer pathway; Joubert syndrome; DNA repair pathways, full network; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; Neurogenesis regulation in the olfactory epithelium; DNA damage response"	"Resolution of D-loop Structures through Holliday Junction Intermediates; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Cytosolic sensors of pathogen-associated DNA ; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; Meiotic recombination; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; DNA Damage/Telomere Stress Induced Senescence; Nonhomologous End-Joining (NHEJ); HDR through MMEJ (alt-NHEJ); Sensing of DNA Double Strand Breaks; IRF3-mediated induction of type I IFN"	"32"	"0"	"878.4"	"666.2"	"901.2"	"827.7"	"908.0"	"875.6"	"1046.8"	"1339.1"	"2191.4"	"4044.9"	"6771.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30876"	"DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1"	"16"	"14"	"26"	"14"	"1174"	"133.8"	"6.87"	"4988.76"	"51.61"	"12"	"14"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00562, Pf04560, Pf04561, Pf04563, Pf04565, Pf04566, Pf04567"	"5431"	"ENSG00000047315"	"POLR2B"	"A8K1A8; hsa:5431; P30876; Q8IZ61"	"Pyrimidine metabolism; Eukaryotic transcription initiation"	"Estrogen-dependent gene expression; mRNA Splicing - Major Pathway; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Activation of anterior HOX genes in hindbrain development during early embryogenesis; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"43"	"0"	"1122.4"	"1077.5"	"1232.1"	"1031.3"	"1138.5"	"1145.2"	"1378.9"	"1705.9"	"2313.2"	"3438.8"	"4814.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75400"	"Pre-mRNA-processing factor 40 homolog A OS=Homo sapiens OX=9606 GN=PRPF40A PE=1 SV=2"	"14"	"15"	"29"	"15"	"957"	"108.7"	"7.56"	"5847.29"	"51.02"	"14"	"13"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	"Pf00397, Pf01846"	"55660"	"ENSG00000196504"	"PRPF40A"	"hsa:55660; O43856; O75400; O75404; Q8TBQ1; Q9H782; Q9NWU9; Q9P0Q2; Q9Y5A8"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"2063.3"	"1767.6"	"1688.2"	"1570.9"	"1741.9"	"1764.0"	"2269.7"	"3004.1"	"4709.0"	"9111.5"	"12587.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35659"	"Protein DEK OS=Homo sapiens OX=9606 GN=DEK PE=1 SV=1"	"24"	"12"	"28"	"12"	"375"	"42.6"	"8.56"	"5034.65"	"50.23"	"11"	"11"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytoskeleton;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf08766"	"7913"	"ENSG00000124795"	"DEK"	"B2R6K6; B4DN37; hsa:7913; P35659; Q5TGV4; Q5TGV5"	"IL-18 signaling pathway; 10q11.21q11.23 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression; Transcriptional regulation of granulopoiesis; Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors"	"5"	"0"	"558.8"	"493.6"	"546.6"	"503.0"	"542.8"	"570.3"	"664.1"	"816.9"	"3175.3"	"13531.1"	"12739.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15046"	"Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3"	"26"	"13"	"24"	"13"	"597"	"68.0"	"6.35"	"4157.69"	"49.86"	"11"	"13"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00152, Pf01336"	"3735"	"ENSG00000065427"	"KARS1"	"A8MSK1; D3DUK4; hsa:3735; O14946; Q15046; Q96J25; Q9HB23"	""	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation; Mitochondrial tRNA aminoacylation"	"3"	"0"	"571.7"	"475.0"	"598.0"	"535.9"	"609.7"	"584.6"	"738.7"	"977.5"	"2645.7"	"5547.4"	"6376.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62081"	"40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1"	"55"	"10"	"18"	"10"	"194"	"22.1"	"10.10"	"2693.79"	"49.85"	"6"	"10"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf01251"	"6201"	"ENSG00000171863"	"RPS7"	"hsa:6201; P23821; P24818; P62081; Q57Z92; Q6IPH1"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery; rRNA modification in the nucleus and cytosol"	"20"	"0"	"543.6"	"542.2"	"611.4"	"474.0"	"582.1"	"579.1"	"667.4"	"906.2"	"2397.2"	"4993.0"	"5053.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95347"	"Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2"	"14"	"14"	"26"	"14"	"1197"	"135.6"	"8.43"	"4452.91"	"49.75"	"12"	"14"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02463, Pf06470"	"10592"	"ENSG00000136824"	"SMC2"	"hsa:10592; O95347; Q6IEE0; Q9P1P2"	"Retinoblastoma gene in cancer"	"Condensation of Prophase Chromosomes; Condensation of Prometaphase Chromosomes"	"3"	"0"	"941.9"	"832.0"	"975.6"	"812.5"	"936.4"	"986.8"	"1134.1"	"1304.4"	"2158.3"	"3462.7"	"4550.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q07157"	"Tight junction protein ZO-1 OS=Homo sapiens OX=9606 GN=TJP1 PE=1 SV=3"	"9"	"13"	"26"	"13"	"1748"	"195.3"	"6.70"	"5294.58"	"49.63"	"12"	"13"	"cell adhesion;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00595, Pf00625, Pf00791, Pf07653"	"7082"	"ENSG00000104067; ENSG00000277401"	"TJP1"	"B4E3K1; hsa:7082; Q07157; Q2NKP3; Q4ZGJ6"	"Epithelial to mesenchymal transition in colorectal cancer; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Gastrin signaling pathway; Disruption of postsynaptic signaling by CNV; 1q21.1 copy number variation syndrome; CKAP4 signaling pathway map; 15q11q13 copy number variation"	"RUNX1 regulates expression of components of tight junctions; Signaling by Hippo; Regulation of gap junction activity; SARS-CoV-2 targets PDZ proteins in cell-cell junction; Apoptotic cleavage of cell adhesion  proteins"	"12"	"0"	"1210.5"	"1028.4"	"1254.5"	"1075.2"	"1251.2"	"1262.6"	"1469.9"	"1706.1"	"4700.7"	"8258.2"	"9112.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46777"	"60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3"	"33"	"11"	"30"	"11"	"297"	"34.3"	"9.72"	"7071.57"	"49.61"	"11"	"10"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf14204, Pf17144"	"6125"	"ENSG00000122406"	"RPL5"	"hsa:6125; P46777; Q32LZ3; Q53HH6; Q9H3F4"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"15"	"0"	"2265.1"	"1934.1"	"2090.2"	"1849.6"	"2046.4"	"2222.0"	"2716.5"	"3114.6"	"3804.9"	"5249.0"	"7795.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49756"	"RNA-binding protein 25 OS=Homo sapiens OX=9606 GN=RBM25 PE=1 SV=3"	"15"	"10"	"22"	"10"	"843"	"100.1"	"6.32"	"4408.14"	"49.39"	"8"	"9"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf01480"	"58517"	"ENSG00000119707"	"RBM25"	"A0PJL9; B2RNA8; B3KT03; hsa:58517; P49756; Q2TA72; Q5XJ17; Q6P665; Q9H6A1; Q9UEQ5; Q9UIE9"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"686.2"	"601.4"	"589.2"	"536.1"	"593.1"	"622.2"	"761.8"	"962.4"	"1698.0"	"3511.2"	"5071.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96E39"	"RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1"	"29"	"9"	"26"	"3"	"390"	"42.1"	"9.89"	"5084.16"	"49.27"	"9"	"9"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf08081"	"494115"	"ENSG00000213516"	"RBMXL1"	"hsa:494115; Q96E39"	""	""	"0"	"0"	"482.6"	"460.0"	"483.9"	"446.3"	"451.1"	"453.3"	"551.5"	"617.6"	"703.9"	"1032.1"	"1693.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12905"	"Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2"	"33"	"9"	"17"	"9"	"390"	"43.0"	"5.26"	"3326.96"	"48.64"	"6"	"9"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf07528"	"3608"	"ENSG00000143621"	"ILF2"	"A6NDB0; B2R8G7; hsa:3608; Q12905; Q5SR10; Q5SR11; Q7L7R3; Q9BWD4; Q9P1N0"	"B cell receptor signaling pathway"	"Neutrophil degranulation"	"2"	"0"	"908.8"	"882.1"	"948.5"	"807.6"	"919.7"	"865.3"	"1072.0"	"1338.8"	"1701.1"	"2678.4"	"3970.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P29692"	"Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5"	"46"	"14"	"28"	"12"	"281"	"31.1"	"5.01"	"6393.46"	"48.37"	"12"	"10"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00736, Pf10587"	"1936"	"ENSG00000104529; ENSG00000273594"	"EEF1D"	"B4DDU4; D3DWK3; E9PBQ9; hsa:1936; P29692; Q4VBZ6; Q969J1; Q96I38"	"Translation factors"	"Eukaryotic Translation Elongation"	"2"	"2"	"1030.7"	"993.2"	"1015.5"	"903.4"	"995.0"	"1066.9"	"1250.0"	"1550.3"	"2466.9"	"4754.1"	"7134.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P47897"	"Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1"	"18"	"11"	"28"	"10"	"775"	"87.7"	"7.15"	"5743.87"	"48.21"	"10"	"11"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;mitochondrion;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00749, Pf03950, Pf04557, Pf04558"	"5859"	"ENSG00000172053"	"QARS1"	"B4DWJ2; hsa:5859; P47897"	""	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation; Mitochondrial tRNA aminoacylation"	"3"	"0"	"332.6"	"309.8"	"349.0"	"324.7"	"325.3"	"347.6"	"414.9"	"495.3"	"1076.3"	"2766.3"	"4650.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43395"	"U4/U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2"	"23"	"12"	"24"	"12"	"683"	"77.5"	"9.50"	"4463.94"	"48.17"	"10"	"12"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf01480, Pf06544, Pf08572"	"9129"	"ENSG00000117360"	"PRPF3"	"B4DSY9; hsa:9129; O43395; O43446; Q5VT54"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"1042.2"	"965.4"	"1129.6"	"953.6"	"1099.1"	"1033.1"	"1200.3"	"1452.4"	"2301.1"	"3808.9"	"5349.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61604"	"10 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPE1 PE=1 SV=2"	"77"	"12"	"24"	"12"	"102"	"10.9"	"8.92"	"4181.24"	"48.15"	"7"	"12"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"mitochondrion"	"other molecular function"	"Pf00166"	"3336"	"ENSG00000115541"	"HSPE1"	"hsa:3336; O95421; P61604; Q04984; Q53X54; Q9UDH0"	""	"RHOG GTPase cycle"	"1"	"0"	"322.1"	"315.9"	"392.3"	"337.0"	"405.1"	"692.4"	"1635.3"	"3894.1"	"6901.5"	"10252.7"	"18025.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62258"	"14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1"	"56"	"12"	"32"	"10"	"255"	"29.2"	"4.74"	"8676.24"	"48.09"	"11"	"11"	"stress response;transport;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00244"	"7531"	"ENSG00000108953; ENSG00000274474"	"YWHAE"	"B3KY71; D3DTH5; hsa:7531; P29360; P42655; P62258; Q4VJB6; Q53XZ5; Q63631; Q7M4R4"	"Cell cycle; Myometrial relaxation and contraction pathways; VEGFA-VEGFR2 signaling; Calcium regulation in cardiac cells; 17p13.3 (YWHAE) copy number variation; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Translocation of SLC2A4 (GLUT4) to the plasma membrane; TP53 Regulates Metabolic Genes; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Activation of BAD and translocation to mitochondria ; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models; RAB GEFs exchange GTP for GDP on RABs; Regulation of HSF1-mediated heat shock response; Signaling by Hippo; HSF1 activation; NADE modulates death signalling"	"26"	"3"	"1861.7"	"1492.7"	"1760.3"	"1524.6"	"1835.6"	"1929.9"	"2360.5"	"2869.7"	"4502.4"	"7099.5"	"9968.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75475"	"PC4 and SFRS1-interacting protein OS=Homo sapiens OX=9606 GN=PSIP1 PE=1 SV=1"	"26"	"12"	"30"	"12"	"530"	"60.1"	"9.13"	"5098.54"	"47.95"	"11"	"12"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00855, Pf11467"	"11168"	"ENSG00000164985"	"PSIP1"	"D3DRI9; hsa:11168; O00256; O75475; O95368; Q6P391; Q86YB9; Q9NZI3; Q9UER6"	"MECP2 and associated Rett syndrome"	"Formation of WDR5-containing histone-modifying complexes; Vpr-mediated nuclear import of PICs; 2-LTR circle formation; Integration of viral DNA into host genomic DNA; Autointegration results in viral DNA circles; APOBEC3G mediated resistance to HIV-1 infection"	"8"	"0"	"964.5"	"883.7"	"968.9"	"808.0"	"913.9"	"1038.8"	"1168.6"	"1361.2"	"2943.8"	"4072.9"	"4317.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3I0"	"RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1"	"27"	"13"	"27"	"13"	"505"	"55.2"	"7.23"	"4079.94"	"47.93"	"12"	"12"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01139"	"51493"	"ENSG00000100220"	"RTCB"	"B2R6A8; hsa:51493; Q6IAI0; Q9BWL4; Q9NTH1; Q9P037; Q9P0J3; Q9Y3I0"	"Unfolded protein response"	"tRNA processing in the nucleus"	"2"	"0"	"1376.5"	"1254.3"	"1403.6"	"1204.0"	"1382.0"	"1412.3"	"1611.1"	"1879.3"	"3603.3"	"5254.7"	"6697.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H0D6"	"5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1"	"19"	"13"	"24"	"13"	"950"	"108.5"	"7.47"	"5345.93"	"47.81"	"10"	"11"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03159, Pf17846"	"22803"	"ENSG00000088930"	"XRN2"	"hsa:22803; Q3L8N4; Q6KGZ9; Q9BQL1; Q9H0D6; Q9NTW0; Q9NXS6; Q9UL53"	"mRNA processing"	"Major pathway of rRNA processing in the nucleolus and cytosol; Association of TriC/CCT with target proteins during biosynthesis"	"3"	"0"	"1274.1"	"1083.7"	"1380.7"	"1226.0"	"1323.4"	"1264.7"	"1537.5"	"1899.0"	"3119.8"	"4975.1"	"7183.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31948"	"Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1"	"28"	"14"	"21"	"14"	"543"	"62.6"	"6.80"	"2714.07"	"47.74"	"6"	"14"	"other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00515, Pf13181, Pf17830"	"10963"	"ENSG00000168439"	"STIP1"	"B4DM70; F5H0T1; G3XAD8; hsa:10963; P31948; Q3ZCU9; Q5TZU9"	"VEGFA-VEGFR2 signaling"	"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; RND1 GTPase cycle"	"3"	"0"	"709.4"	"735.0"	"748.0"	"682.2"	"728.1"	"764.9"	"919.2"	"1181.7"	"1959.9"	"7316.4"	"17759.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63104"	"14-3-3 protein zeta/delta OS=Homo sapiens OX=9606 GN=YWHAZ PE=1 SV=1"	"44"	"10"	"25"	"8"	"245"	"27.7"	"4.79"	"5220.16"	"47.73"	"9"	"10"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00244"	"7534"	"ENSG00000164924"	"YWHAZ"	"A8K1N0; B7Z465; hsa:7534; P29213; P29312; P63104; Q32P43; Q5XJ08; Q6GPI2; Q6IN74; Q6NUR9; Q6P3U9; Q86V33"	"Cell cycle; Prolactin signaling pathway; Pathogenic Escherichia coli infection; Myometrial relaxation and contraction pathways; Hepatitis B infection; GDNF signaling; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Regulation of localization of FOXO transcription factors; Negative regulation of NOTCH4 signaling; Deactivation of the beta-catenin transactivating complex; Interleukin-3, Interleukin-5 and GM-CSF signaling; TP53 Regulates Metabolic Genes; NOTCH4 Activation and Transmission of Signal to the Nucleus; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; Rap1 signalling; KSRP (KHSRP) binds and destabilizes mRNA; GP1b-IX-V activation signalling; Activation of BAD and translocation to mitochondria"	"23"	"0"	"1053.6"	"775.6"	"1078.1"	"1023.4"	"1072.4"	"1086.4"	"1235.9"	"1407.2"	"2096.5"	"2859.0"	"3979.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13523"	"Serine/threonine-protein kinase PRP4 homolog OS=Homo sapiens OX=9606 GN=PRPF4B PE=1 SV=3"	"14"	"12"	"27"	"11"	"1007"	"116.9"	"10.26"	"5329.89"	"47.34"	"10"	"10"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"8899"	"ENSG00000112739"	"PRPF4B"	"A8K5C9; hsa:8899; Q13523; Q5D0F6; Q5TAY8; Q8IVC3; Q8TDP2; Q96QT7; Q9UEE6"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"1"	"1418.5"	"1308.1"	"1458.0"	"1289.8"	"1491.1"	"1469.8"	"1701.2"	"1963.2"	"3689.2"	"7646.1"	"10538.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P16152"	"Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3"	"39"	"10"	"22"	"10"	"277"	"30.4"	"8.32"	"4109.29"	"47.32"	"9"	"10"	"other metabolic processes;other biological processes"	"cytosol"	"other molecular function"	"Pf00106"	"873"	"ENSG00000159228"	"CBR1"	"B2RBZ7; B4DFK7; hsa:873; P16152; Q3LHW8"	"Nuclear receptors meta-pathway; NRF2 pathway; Prostaglandin synthesis and regulation"	"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)"	"4"	"0"	"253.2"	"221.3"	"312.4"	"265.3"	"307.8"	"322.3"	"424.8"	"762.4"	"1996.9"	"4903.4"	"8496.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75937"	"DnaJ homolog subfamily C member 8 OS=Homo sapiens OX=9606 GN=DNAJC8 PE=1 SV=2"	"41"	"11"	"22"	"11"	"253"	"29.8"	"9.06"	"3602.46"	"47.19"	"9"	"10"	""	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00226"	"22826"	"ENSG00000126698; ENSG00000285317"	"DNAJC8"	"B4DUU4; D3DPM0; hsa:22826; O75937; Q6IBA4; Q8N4Z5; Q9P051; Q9P067"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"811.2"	"628.7"	"827.1"	"708.1"	"835.7"	"848.2"	"1115.6"	"1923.6"	"4451.2"	"5729.7"	"6591.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12904"	"Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 OS=Homo sapiens OX=9606 GN=AIMP1 PE=1 SV=2"	"43"	"11"	"25"	"11"	"312"	"34.3"	"8.43"	"4990.40"	"47.19"	"11"	"11"	"cell-cell signaling;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf01588"	"9255"	"ENSG00000164022"	"AIMP1"	"B3KTR2; B4E1S7; hsa:9255; Q12904; Q6FG28; Q96CQ9"	"Ciliary landscape"	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"3"	"0"	"453.5"	"418.6"	"499.7"	"426.2"	"472.2"	"476.5"	"575.7"	"739.8"	"2534.5"	"5894.9"	"8145.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P38919"	"Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4"	"33"	"12"	"23"	"12"	"411"	"46.8"	"6.73"	"5099.40"	"47.17"	"10"	"10"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"9775"	"ENSG00000141543"	"EIF4A3"	"hsa:9775; P38919; Q15033; Q6IBQ2; Q96A18"	"TAR syndrome"	"mRNA Splicing - Major Pathway; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Deadenylation of mRNA; ISG15 antiviral mechanism; Transport of Mature mRNA derived from an Intron-Containing Transcript"	"9"	"0"	"755.9"	"721.0"	"805.4"	"666.6"	"745.0"	"788.7"	"929.4"	"1135.7"	"1856.0"	"4767.6"	"9146.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P42704"	"Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3"	"11"	"15"	"28"	"15"	"1394"	"157.8"	"6.13"	"5043.82"	"47.08"	"12"	"13"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"other membranes;cytoskeleton;mitochondrion;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf01535"	"10128"	"ENSG00000138095"	"LRPPRC"	"A0PJE3; A8K1V1; hsa:10128; P42704; Q53PC0; Q53QN7; Q6ZUD8; Q7Z7A6; Q96D84"	"Ciliary landscape"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"4"	"0"	"1000.5"	"985.0"	"1117.5"	"939.5"	"1126.1"	"1105.9"	"1337.7"	"1769.5"	"3200.1"	"6657.0"	"10572.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92922"	"SWI/SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3"	"12"	"10"	"22"	"9"	"1105"	"122.8"	"5.76"	"4281.45"	"46.97"	"8"	"10"	"cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00249, Pf04433, Pf16495, Pf16496, Pf16498"	"6599"	"ENSG00000173473"	"SMARCC1"	"hsa:6599; Q17RS0; Q6P172; Q8IWH2; Q92922"	"Androgen receptor network in prostate cancer; Tumor suppressor activity of SMARCB1; Thermogenesis; Kleefstra syndrome"	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; RMTs methylate histone arginines"	"6"	"1"	"930.8"	"807.6"	"966.4"	"866.7"	"1042.6"	"985.8"	"1132.3"	"1331.6"	"2457.4"	"4326.6"	"5804.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96AE4"	"Far upstream element-binding protein 1 OS=Homo sapiens OX=9606 GN=FUBP1 PE=1 SV=3"	"19"	"14"	"30"	"9"	"644"	"67.5"	"7.61"	"4942.86"	"46.90"	"13"	"14"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00013, Pf09005"	"8880"	"ENSG00000162613"	"FUBP1"	"hsa:8880; Q12828; Q96AE4"	""	""	"0"	"2"	"1017.1"	"1031.4"	"1090.4"	"926.1"	"1106.1"	"982.6"	"1285.8"	"1550.9"	"2093.8"	"3243.1"	"4594.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BXJ9"	"N-alpha-acetyltransferase 15, NatA auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA15 PE=1 SV=1"	"18"	"16"	"23"	"14"	"866"	"101.2"	"7.42"	"2556.40"	"46.83"	"8"	"13"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity"	"Pf12569, Pf13181"	"80155"	"ENSG00000164134"	"NAA15"	"D3DNY6; hsa:80155; Q52LG9; Q8IWH4; Q8NEV2; Q9BXJ9; Q9H8P6"	""	""	"0"	"2"	"381.3"	"337.5"	"448.8"	"405.6"	"438.2"	"437.2"	"486.6"	"598.9"	"1702.1"	"8080.4"	"12270.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P24534"	"Elongation factor 1-beta OS=Homo sapiens OX=9606 GN=EEF1B2 PE=1 SV=3"	"71"	"12"	"25"	"10"	"225"	"24.7"	"4.67"	"4811.12"	"46.76"	"8"	"9"	"protein metabolism;other metabolic processes"	"cytosol;other cell component"	"enzyme regulator activity;nucleic acid binding activity"	"Pf00736, Pf10587"	"1933"	"ENSG00000114942; ENSG00000283391"	"EEF1B2"	"A8K795; hsa:1933; P24534; Q6IBH9"	"Translation factors"	"Eukaryotic Translation Elongation"	"2"	"0"	"1431.2"	"1416.2"	"1259.9"	"1187.9"	"1334.2"	"1216.5"	"1558.6"	"1797.6"	"2869.6"	"6060.3"	"9002.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96DI7"	"U5 small nuclear ribonucleoprotein 40 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP40 PE=1 SV=1"	"37"	"10"	"21"	"10"	"357"	"39.3"	"8.10"	"4357.05"	"46.54"	"9"	"10"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf00400"	"9410"	"ENSG00000060688"	"SNRNP40"	"B4DQJ1; hsa:9410; O75938; O95320; Q96DI7"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"3"	"0"	"545.7"	"464.8"	"553.8"	"483.6"	"548.7"	"539.7"	"641.4"	"859.6"	"1556.4"	"3365.3"	"5739.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55072"	"Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4"	"23"	"16"	"32"	"16"	"806"	"89.3"	"5.26"	"6765.25"	"46.50"	"15"	"12"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"non-structural extracellular;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00004, Pf02359, Pf02933, Pf09336, Pf17862"	"7415"	"ENSG00000165280"	"VCP"	"B2R5T8; hsa:7415; P55072; Q0V924; Q2TAI5; Q969G7; Q9UCD5"	"Alstrom syndrome; Clock-controlled autophagy in bone metabolism"	"Neddylation; Neutrophil degranulation; E3 ubiquitin ligases ubiquitinate target proteins; ABC-family proteins mediated transport; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Defective CFTR causes cystic fibrosis; KEAP1-NFE2L2 pathway; Aggrephagy; Attachment and Entry; Attachment and Entry; Ovarian tumor domain proteases; Josephin domain DUBs; Protein methylation; RHOH GTPase cycle; HSF1 activation; Translesion Synthesis by POLH; N-glycan trimming in the ER and Calnexin/Calreticulin cycle"	"20"	"0"	"2022.3"	"1923.5"	"2133.3"	"1785.7"	"2006.2"	"1905.1"	"2366.9"	"2766.0"	"3309.0"	"4322.5"	"5542.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49591"	"Serine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=SARS1 PE=1 SV=3"	"34"	"16"	"23"	"16"	"514"	"58.7"	"6.43"	"3842.80"	"46.43"	"11"	"12"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00587, Pf02403"	"6301"	"ENSG00000031698"	"SARS1"	"B2R6Y9; hsa:6301; P49591; Q5T5C8; Q9NSE3"	"VEGFA-VEGFR2 signaling"	"Cytosolic tRNA aminoacylation; Selenocysteine synthesis"	"3"	"0"	"625.8"	"592.5"	"690.4"	"606.2"	"675.6"	"635.0"	"842.5"	"1310.2"	"4794.4"	"7392.8"	"8595.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16531"	"DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1"	"13"	"14"	"27"	"14"	"1140"	"126.9"	"5.26"	"4863.43"	"46.42"	"13"	"14"	"cell-cell signaling;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03178, Pf10433"	"1642"	"ENSG00000167986"	"DDB1"	"A6NG77; B2R648; B4DG00; hsa:1642; O15176; Q13289; Q16531; Q58F96"	"Hippo-Merlin signaling dysregulation; Hepatitis B infection; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"Neddylation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; DNA Damage Recognition in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; Dual Incision in GG-NER"	"14"	"0"	"730.0"	"690.4"	"791.5"	"721.6"	"790.9"	"756.9"	"921.3"	"1100.2"	"2445.9"	"6156.1"	"10102.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16630"	"Cleavage and polyadenylation specificity factor subunit 6 OS=Homo sapiens OX=9606 GN=CPSF6 PE=1 SV=2"	"25"	"9"	"20"	"9"	"551"	"59.2"	"7.15"	"3693.58"	"46.39"	"7"	"9"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00076"	"11052"	"ENSG00000111605"	"CPSF6"	"A8K7K9; hsa:11052; Q16630; Q53ES1; Q9BSJ7; Q9BW18"	""	"Signaling by cytosolic FGFR1 fusion mutants; Signaling by FGFR1 in disease"	"2"	"0"	"338.8"	"351.2"	"330.4"	"285.7"	"351.5"	"317.1"	"396.9"	"531.5"	"1104.6"	"2856.7"	"5178.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q1KMD3"	"Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1"	"19"	"13"	"26"	"13"	"747"	"85.1"	"4.91"	"4738.38"	"46.11"	"12"	"11"	""	"nucleus;other cell component"	""	"Pf00622, Pf02037, Pf13671"	"221092"	"ENSG00000214753"	"HNRNPUL2"	"hsa:221092; Q1KMD3; Q8N3B3"	""	""	"0"	"0"	"1014.7"	"1099.1"	"1151.2"	"898.7"	"1132.2"	"1120.5"	"1292.1"	"1686.2"	"2549.4"	"4064.0"	"6134.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P42166"	"Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2"	"21"	"11"	"20"	"5"	"694"	"75.4"	"7.66"	"4073.82"	"45.96"	"8"	"10"	""	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03020, Pf08198, Pf11560"	"7112"	"ENSG00000120802"	"TMPO"	"P08918; P08919; P42166; Q14860; Q16295"	"Envelope proteins and their potential roles in EDMD physiopathology; Overlap between signal transduction pathways contributing to LMNA laminopathies"	""	"2"	"7"	"696.7"	"594.8"	"703.7"	"642.1"	"716.3"	"693.8"	"796.3"	"1071.9"	"3006.3"	"4592.0"	"6129.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NC51"	"Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2"	"34"	"16"	"27"	"16"	"408"	"44.9"	"8.65"	"6649.16"	"45.85"	"14"	"11"	"cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf04774, Pf16174"	"26135"	"ENSG00000142864"	"SERBP1"	"hsa:26135; Q5VU19; Q5VU20; Q5VU22; Q8NC51; Q8WUH0; Q96SE2; Q9BTY3; Q9BUM4; Q9Y367; Q9Y4S3"	"Apoptosis-related network due to altered Notch3 in ovarian cancer"	""	"1"	"0"	"2813.6"	"2379.0"	"2661.6"	"2287.4"	"2469.1"	"2737.7"	"3236.8"	"3202.6"	"3609.4"	"5437.9"	"9176.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50570"	"Dynamin-2 OS=Homo sapiens OX=9606 GN=DNM2 PE=1 SV=2"	"14"	"10"	"25"	"8"	"870"	"98.0"	"7.44"	"4887.11"	"45.76"	"9"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00169, Pf00350, Pf01031, Pf02212"	"1785"	"ENSG00000079805"	"DNM2"	"A8K1B6; E7EV30; E9PEQ4; hsa:1785; K7ESI9; P50570; Q5I0Y0; Q7Z5S3; Q9UPH4"	"Synaptic vesicle pathway; Fragile X syndrome; Intracellular trafficking proteins involved in CMT neuropathy"	"Clathrin-mediated endocytosis; Recycling pathway of L1; MHC class II antigen presentation; Lysosome Vesicle Biogenesis; NGF-stimulated transcription; Golgi Associated Vesicle Biogenesis; Toll Like Receptor 4 (TLR4) Cascade; NOSTRIN mediated eNOS trafficking; Retrograde neurotrophin signalling; Formation of annular gap junctions"	"14"	"3"	"351.6"	"340.1"	"451.0"	"378.3"	"437.9"	"486.8"	"596.1"	"1030.6"	"2148.2"	"4217.6"	"6297.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q07955"	"Serine/arginine-rich splicing factor 1 OS=Homo sapiens OX=9606 GN=SRSF1 PE=1 SV=2"	"48"	"12"	"25"	"12"	"248"	"27.7"	"10.36"	"4108.42"	"45.52"	"10"	"11"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6426"	"ENSG00000136450"	"SRSF1"	"B2R6Z7; D3DTZ3; hsa:6426; Q07955; Q13809"	"mRNA processing"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"7"	"0"	"1599.8"	"1756.6"	"1408.7"	"1313.3"	"1402.0"	"1442.8"	"1907.6"	"2320.3"	"2419.9"	"3106.0"	"4261.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQ61"	"Telomerase RNA component interacting RNase OS=Homo sapiens OX=9606 GN=TRIR PE=1 SV=1"	"28"	"8"	"13"	"8"	"176"	"18.4"	"9.44"	"1565.84"	"45.41"	"3"	"8"	"RNA metabolism OR transcription;other metabolic processes"	""	"nucleic acid binding activity;other molecular function"	""	"79002"	"ENSG00000123144"	"TRIR"	"hsa:79002; Q9BQ61"	""	""	"0"	"0"	"760.4"	"711.1"	"750.1"	"704.9"	"750.5"	"707.0"	"883.8"	"991.4"	"2250.6"	"3737.6"	"4178.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q10570"	"Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2"	"11"	"15"	"28"	"15"	"1443"	"160.8"	"6.40"	"4551.54"	"45.23"	"13"	"15"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03178, Pf10433"	"29894"	"ENSG00000071894; ENSG00000285049"	"CPSF1"	"hsa:29894; Q10570; Q96AF0"	"mRNA processing"	"Transport of Mature mRNA Derived from an Intronless Transcript; tRNA processing in the nucleus; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"7"	"0"	"1122.3"	"1090.3"	"1318.7"	"1029.6"	"1139.4"	"1169.0"	"1519.6"	"1953.6"	"3084.4"	"7069.6"	"10885.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61158"	"Actin-related protein 3 OS=Homo sapiens OX=9606 GN=ACTR3 PE=1 SV=3"	"34"	"11"	"22"	"11"	"418"	"47.3"	"5.88"	"3603.68"	"45.17"	"10"	"11"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00022"	"10096"	"ENSG00000115091"	"ACTR3"	"hsa:10096; P32391; P61158; Q53QM2"	"Physico-chemical features and toxicity-associated pathways"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Clathrin-mediated endocytosis; EPHB-mediated forward signaling"	"6"	"0"	"640.7"	"623.9"	"695.4"	"623.1"	"751.6"	"941.4"	"1434.6"	"2135.3"	"4549.5"	"6924.2"	"8893.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UHB6"	"LIM domain and actin-binding protein 1 OS=Homo sapiens OX=9606 GN=LIMA1 PE=1 SV=1"	"16"	"10"	"23"	"10"	"759"	"85.2"	"6.84"	"4307.94"	"44.86"	"9"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412"	"51474"	"ENSG00000050405"	"LIMA1"	"B2RB09; hsa:51474; Q2TAN7; Q59FE8; Q9BVF2; Q9H8J1; Q9HBN5; Q9NX96; Q9NXC3; Q9NXU6; Q9P0H8; Q9UHB5; Q9UHB6"	""	""	"0"	"0"	"897.3"	"815.6"	"887.8"	"819.2"	"998.2"	"1018.6"	"1093.6"	"1190.1"	"2024.7"	"4371.9"	"5238.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NI27"	"THO complex subunit 2 OS=Homo sapiens OX=9606 GN=THOC2 PE=1 SV=2"	"8"	"11"	"29"	"11"	"1593"	"182.7"	"8.44"	"5470.11"	"44.82"	"11"	"10"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf11262, Pf11732, Pf16134"	"57187"	"ENSG00000125676"	"THOC2"	"A6NM50; hsa:57187; Q5JZ12; Q6IN92; Q8NI27; Q9H8I6"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"3"	"0"	"1617.2"	"1285.6"	"1508.3"	"1415.8"	"1586.0"	"1561.4"	"1773.9"	"1967.9"	"3251.3"	"4854.0"	"6627.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23381"	"Tryptophan--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=WARS1 PE=1 SV=2"	"31"	"10"	"16"	"10"	"471"	"53.1"	"6.23"	"2013.24"	"44.72"	"5"	"10"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00458, Pf00579"	"7453"	"ENSG00000140105"	"WARS1"	"A6NGN1; A6NID3; hsa:7453; P23381; P78535; Q502Y0; Q53XB6; Q9UDI5; Q9UDL3"	"Photodynamic therapy-induced unfolded protein response; Amino acid metabolism"	"Cytosolic tRNA aminoacylation"	"3"	"0"	"106.1"	"101.9"	"163.4"	"122.8"	"140.9"	"142.2"	"180.8"	"251.4"	"1271.3"	"3782.3"	"6774.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6UN15"	"Pre-mRNA 3'-end-processing factor FIP1 OS=Homo sapiens OX=9606 GN=FIP1L1 PE=1 SV=1"	"22"	"8"	"24"	"8"	"594"	"66.5"	"5.59"	"5439.79"	"44.63"	"7"	"7"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	""	"Pf05182"	"81608"	"ENSG00000145216"	"FIP1L1"	"B4DIR3; G3XAD6; hsa:81608; Q0VGE0; Q499Y4; Q49AU3; Q6UN15; Q7Z608; Q8WVN3; Q96F80; Q9H077"	""	"Transport of Mature mRNA Derived from an Intronless Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs; Signaling by cytosolic PDGFRA and PDGFRB fusion proteins"	"6"	"0"	"997.9"	"880.5"	"997.2"	"866.6"	"968.6"	"969.1"	"1067.8"	"1216.7"	"1531.7"	"2248.6"	"3100.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12972"	"Nuclear inhibitor of protein phosphatase 1 OS=Homo sapiens OX=9606 GN=PPP1R8 PE=1 SV=2"	"28"	"8"	"16"	"8"	"351"	"38.5"	"7.37"	"3283.19"	"44.48"	"5"	"6"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00498"	"5511"	"ENSG00000117751"	"PPP1R8"	"hsa:5511; Q12972; Q5TEJ2; Q5TEJ4; Q5TIF2; Q6PKF6; Q9UBH1; Q9UBZ0"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"243.7"	"228.4"	"264.9"	"248.0"	"280.7"	"264.5"	"313.1"	"370.3"	"1042.5"	"2807.6"	"3495.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43583"	"Density-regulated protein OS=Homo sapiens OX=9606 GN=DENR PE=1 SV=2"	"43"	"7"	"18"	"7"	"198"	"22.1"	"5.30"	"3339.31"	"44.34"	"6"	"6"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	""	"nucleic acid binding activity"	"Pf01253"	"8562"	"ENSG00000139726"	"DENR"	"hsa:8562; O43583; Q9H3U6; Q9UKZ0"	""	""	"0"	"0"	"227.5"	"217.0"	"250.4"	"223.2"	"275.9"	"243.8"	"308.4"	"539.8"	"2867.0"	"4535.0"	"5001.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82979"	"SAP domain-containing ribonucleoprotein OS=Homo sapiens OX=9606 GN=SARNP PE=1 SV=3"	"38"	"11"	"27"	"11"	"210"	"23.7"	"6.42"	"5811.32"	"44.27"	"11"	"10"	"other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02037"	"84324"	"ENSG00000205323"	"SARNP"	"A8K393; hsa:84324; P82979; Q9P066"	""	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript"	"3"	"0"	"1124.8"	"969.1"	"1091.0"	"979.6"	"1075.7"	"1166.2"	"1310.5"	"1620.2"	"6820.0"	"8521.7"	"8859.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96ST2"	"Protein IWS1 homolog OS=Homo sapiens OX=9606 GN=IWS1 PE=1 SV=2"	"15"	"11"	"25"	"11"	"819"	"91.9"	"4.69"	"5640.81"	"44.25"	"10"	"10"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus"	""	"Pf08711"	"55677"	"ENSG00000163166"	"IWS1"	"hsa:55677; Q2TB65; Q6P157; Q8N3E8; Q96MI7; Q96ST2; Q9NV97; Q9NWH8"	""	"Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events"	"3"	"0"	"1329.6"	"1225.9"	"1374.6"	"1285.7"	"1372.0"	"1398.4"	"1537.4"	"1750.2"	"2223.5"	"3126.2"	"4151.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NQ29"	"Putative RNA-binding protein Luc7-like 1 OS=Homo sapiens OX=9606 GN=LUC7L PE=1 SV=1"	"17"	"7"	"22"	"3"	"371"	"43.7"	"9.92"	"3093.53"	"44.19"	"5"	"7"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03194"	"55692"	"ENSG00000007392"	"LUC7L"	"B8ZZ13; hsa:55692; Q96S32; Q9NPH4; Q9NQ29"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"272.0"	"294.3"	"311.2"	"255.0"	"319.7"	"305.6"	"361.9"	"469.1"	"1089.2"	"2172.2"	"2943.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P36776"	"Lon protease homolog, mitochondrial OS=Homo sapiens OX=9606 GN=LONP1 PE=1 SV=2"	"12"	"11"	"22"	"11"	"959"	"106.4"	"6.39"	"3474.72"	"44.18"	"8"	"11"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00004, Pf02190, Pf05362"	"9361"	"ENSG00000196365"	"LONP1"	"B3KPH8; D6W635; E5KMH8; F5GZ27; hsa:9361; P36776; P36777; Q8N8K8; Q9UQ95"	""	""	"0"	"0"	"264.2"	"232.8"	"282.0"	"260.2"	"270.3"	"288.5"	"352.5"	"429.5"	"1133.8"	"5489.6"	"8035.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96I24"	"Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2"	"24"	"13"	"29"	"11"	"572"	"61.6"	"8.38"	"4648.17"	"43.92"	"12"	"13"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"translational apparatus;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00013"	"8939"	"ENSG00000107164"	"FUBP3"	"A3KFK8; A3KFL0; hsa:8939; Q92946; Q96I24; Q9BVB6"	""	""	"0"	"0"	"1556.9"	"1286.1"	"1590.1"	"1336.7"	"1511.8"	"1454.5"	"1762.0"	"2161.0"	"3100.2"	"4976.1"	"6628.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75934"	"Pre-mRNA-splicing factor SPF27 OS=Homo sapiens OX=9606 GN=BCAS2 PE=1 SV=1"	"41"	"8"	"19"	"8"	"225"	"26.1"	"5.66"	"3914.39"	"43.80"	"7"	"8"	"RNA metabolism OR transcription;other metabolic processes"	"cytoskeleton;nucleus;other cell component"	""	"Pf05700"	"10286"	"ENSG00000116752"	"BCAS2"	"hsa:10286; O75934; Q6FGS0"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"252.7"	"209.2"	"304.0"	"242.6"	"277.2"	"282.0"	"371.9"	"574.9"	"2016.2"	"4879.1"	"6568.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NVA2"	"Septin-11 OS=Homo sapiens OX=9606 GN=SEPTIN11 PE=1 SV=3"	"32"	"12"	"22"	"10"	"429"	"49.4"	"6.81"	"3832.21"	"43.76"	"9"	"11"	"cell cycle OR cell proliferation"	"cytoskeleton;other cell component"	"other molecular function"	"Pf00735"	"55752"	"ENSG00000138758"	"SEPTIN11"	"B7Z7Z6; E9KL32; hsa:55752; Q4W5G1; Q7L4N1; Q96SP1; Q9NVA2; Q9UFY9"	"22q11.2 copy number variation syndrome"	""	"1"	"2"	"589.2"	"567.6"	"644.0"	"507.8"	"636.6"	"659.6"	"829.5"	"1504.9"	"4154.2"	"7013.3"	"9791.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N7H5"	"RNA polymerase II-associated factor 1 homolog OS=Homo sapiens OX=9606 GN=PAF1 PE=1 SV=2"	"25"	"11"	"20"	"11"	"531"	"59.9"	"4.63"	"3918.57"	"43.63"	"9"	"9"	"cell-cell signaling;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf03985"	"54623"	"ENSG00000006712"	"PAF1"	"hsa:54623; M0QX35; O75239; Q8N7H5; Q9H166; Q9NUU9"	"Endoderm differentiation"	"E3 ubiquitin ligases ubiquitinate target proteins; Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events"	"5"	"0"	"1029.4"	"802.0"	"1007.3"	"981.9"	"973.6"	"1015.0"	"1125.4"	"1355.3"	"1627.4"	"2294.8"	"3371.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NTJ3"	"Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2"	"12"	"14"	"25"	"14"	"1288"	"147.1"	"6.79"	"4395.64"	"43.58"	"10"	"12"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02463, Pf06470"	"10051"	"ENSG00000113810"	"SMC4"	"A6NLT9; D3DNL8; hsa:10051; O95752; Q8NDL4; Q9NTJ3; Q9UNT9"	"Ciliary landscape"	"Condensation of Prophase Chromosomes; Condensation of Prometaphase Chromosomes"	"3"	"0"	"1105.3"	"988.8"	"1153.1"	"961.3"	"1146.5"	"1184.3"	"1264.2"	"1488.8"	"2579.0"	"4470.9"	"5558.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WWY3"	"U4/U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2"	"24"	"10"	"21"	"10"	"499"	"55.4"	"5.78"	"3833.84"	"43.48"	"9"	"10"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01798, Pf09785"	"26121"	"ENSG00000105618; ENSG00000274144; ENSG00000274651; ENSG00000274894; ENSG00000275117; ENSG00000275885; ENSG00000276421; ENSG00000277154; ENSG00000277707; ENSG00000277953"	"PRPF31"	"E7ESA8; F1T0A4; F1T0A5; hsa:26121; Q17RB4; Q8N7F9; Q8WWY3; Q9H271; Q9Y439"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"1505.9"	"1332.3"	"1345.4"	"1237.6"	"1386.3"	"1390.4"	"1658.7"	"2014.5"	"2571.6"	"4095.2"	"5474.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5JSL3"	"Dedicator of cytokinesis protein 11 OS=Homo sapiens OX=9606 GN=DOCK11 PE=1 SV=2"	"7"	"12"	"28"	"12"	"2073"	"237.5"	"7.74"	"6887.36"	"43.47"	"12"	"9"	"signal transduction;other biological processes"	"cytosol"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf06920, Pf11878, Pf14429, Pf20421, Pf20422"	"139818"	"ENSG00000147251"	"DOCK11"	"A6NMF0; hsa:139818; Q5JSL3; Q66M66; Q6ZUJ5; Q86VU8; Q96MN3"	""	"Factors involved in megakaryocyte development and platelet production; CDC42 GTPase cycle; RAC1 GTPase cycle"	"3"	"0"	"548.8"	"495.7"	"585.7"	"549.1"	"835.0"	"1746.4"	"3352.9"	"4308.6"	"1415.1"	"1927.4"	"2304.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13123"	"Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3"	"22"	"15"	"27"	"15"	"557"	"65.6"	"6.64"	"4806.78"	"43.46"	"13"	"13"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf07807, Pf07808"	"3550"	"ENSG00000113141"	"IK"	"hsa:3550; Q13123; Q6IPD8"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"2273.9"	"2073.5"	"2207.8"	"1946.9"	"2189.4"	"2237.6"	"2536.4"	"2809.0"	"3899.9"	"5137.2"	"6417.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P84243"	"Histone H3.3 OS=Homo sapiens OX=9606 GN=H3-3A PE=1 SV=2"	"55"	"8"	"24"	"1"	"136"	"15.3"	"11.27"	"4000.75"	"43.42"	"7"	"8"	"cell organization and biogenesis;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125"	"3020; 3021"	"ENSG00000132475; ENSG00000163041"	"H3-3A; H3-3B"	"hsa:3020; hsa:3021; P06351; P33155; P84243; Q5VV55; Q5VV56; Q66I33; Q9V3W4"	"Gastric cancer network 1; Histone modifications; Tumor suppressor activity of SMARCB1; Ciliary landscape; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; DYRK1A involvement regarding cell proliferation in brain development; 4p16.3 copy number variation; 5q35 copy number variation"	"Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Senescence-Associated Secretory Phenotype (SASP); RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Transcriptional regulation of granulopoiesis; Transcriptional regulation by small RNAs; B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Promoter Escape; Inhibition of DNA recombination at telomere; Amyloid fiber formation; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Formation of the beta-catenin:TCF transactivating complex; Oxidative Stress Induced Senescence; Pre-NOTCH Transcription and Translation; Factors involved in megakaryocyte development and platelet production; Meiotic recombination; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Condensation of Prophase Chromosomes; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; RNA Polymerase I Promoter Opening"	"34"	"10"	"1604.5"	"1350.9"	"1371.4"	"1127.6"	"994.5"	"1412.3"	"1547.4"	"2108.1"	"3191.1"	"4746.3"	"6689.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P67809"	"Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3"	"37"	"7"	"16"	"6"	"324"	"35.9"	"9.88"	"2496.81"	"43.10"	"4"	"7"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00313"	"4904"	"ENSG00000065978"	"YBX1"	"hsa:4904; P16990; P16991; P67809; Q14972; Q15325; Q5FVF0"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; MECP2 and associated Rett syndrome; mRNA processing; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Processing of Capped Intron-Containing Pre-mRNA; mRNA Splicing - Major Pathway; Interferon gamma signaling; SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; mRNA Splicing - Minor Pathway; Noncanonical activation of NOTCH3"	"10"	"1"	"354.4"	"350.6"	"321.6"	"302.4"	"324.5"	"341.8"	"409.5"	"463.4"	"543.5"	"757.0"	"1086.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05023"	"Sodium/potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1"	"13"	"11"	"23"	"11"	"1023"	"112.8"	"5.49"	"5065.98"	"43.05"	"10"	"9"	"transport;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;other cell component"	"transporter activity;other molecular function"	"Pf00122, Pf00689, Pf00690, Pf13246"	"476"	"ENSG00000163399"	"ATP1A1"	"B2RBR6; B7Z2T5; B7Z3U6; F5H3A1; hsa:476; P05023; Q16689; Q6LDM4; Q9UCN1; Q9UJ20; Q9UJ21"	"Pre-implantation embryo; Proximal tubule transport; Arsenic metabolism and reactive oxygen species generation"	"Potential therapeutics for SARS; Ion homeostasis; Ion transport by P-type ATPases"	"6"	"0"	"400.5"	"376.4"	"471.8"	"434.2"	"438.4"	"407.8"	"505.1"	"636.9"	"1732.6"	"4290.4"	"6441.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EK5"	"KIF-binding protein OS=Homo sapiens OX=9606 GN=KIFBP PE=1 SV=1"	"23"	"12"	"20"	"11"	"621"	"71.8"	"5.49"	"3368.35"	"43.01"	"8"	"12"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes"	"cytoskeleton;mitochondrion"	"cytoskeletal activity"	"Pf12309"	"26128"	"ENSG00000198954"	"KIFBP"	"A8K5M8; hsa:26128; Q96EK5; Q9BR89; Q9ULE1; Q9Y428"	""	""	"0"	"1"	"242.9"	"263.7"	"316.9"	"256.6"	"302.5"	"348.8"	"605.0"	"1872.7"	"6444.6"	"6747.3"	"5248.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P40227"	"T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3"	"28"	"11"	"19"	"11"	"531"	"58.0"	"6.68"	"3418.60"	"43.00"	"6"	"9"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00118"	"908"	"ENSG00000146731"	"CCT6A"	"A6NCD2; hsa:908; P40227; Q3KP28; Q75LP4; Q96S46"	"16p11.2 proximal deletion syndrome"	"Formation of tubulin folding intermediates by CCT/TriC; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; RHOBTB2 GTPase cycle; Folding of actin by CCT/TriC"	"7"	"0"	"299.2"	"286.7"	"401.1"	"307.5"	"337.5"	"377.3"	"410.9"	"535.3"	"1166.0"	"5236.4"	"12005.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15042"	"U2 snRNP-associated SURP motif-containing protein OS=Homo sapiens OX=9606 GN=U2SURP PE=1 SV=2"	"14"	"14"	"27"	"13"	"1029"	"118.2"	"8.47"	"5441.90"	"42.98"	"14"	"11"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf00076, Pf01805, Pf04818, Pf08312"	"23350"	"ENSG00000163714"	"U2SURP"	"A0PJ60; hsa:23350; O15042; Q0D2M1; Q2NKQ7; Q9BR70"	""	"mRNA Splicing - Major Pathway"	"1"	"1"	"1927.3"	"1539.2"	"2062.8"	"1848.4"	"2006.5"	"2047.0"	"2366.4"	"2547.7"	"3377.5"	"6253.1"	"9252.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13647"	"Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3"	"20"	"14"	"30"	"8"	"590"	"62.3"	"7.74"	"4833.29"	"42.96"	"12"	"13"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;other cell component"	"bone, tooth or skin structural activity;cytoskeletal activity;other molecular function"	"Pf00038, Pf16208"	"3852"	"ENSG00000186081"	"KRT5"	"hsa:3852; P13647; Q6PI71; Q6UBJ0; Q8TA91"	""	"Formation of the cornified envelope; Type I hemidesmosome assembly"	"3"	"0"	"213.5"	"492.6"	"472.5"	"336.4"	"793.7"	"286.8"	"502.8"	"899.4"	"698.8"	"4184.0"	"2358.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P53396"	"ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3"	"15"	"14"	"25"	"14"	"1101"	"120.8"	"7.33"	"5181.64"	"42.95"	"13"	"12"	"other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00285, Pf00549, Pf02629, Pf16114"	"47"	"ENSG00000131473"	"ACLY"	"B4DIM0; B4E3P0; hsa:47; P53396; Q13037; Q9BRL0"	"Sterol regulatory element-binding proteins (SREBP) signaling; TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Fatty acid biosynthesis; Amino acid metabolism; Lipid metabolism pathway; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer"	"Neutrophil degranulation; ChREBP activates metabolic gene expression; Fatty acyl-CoA biosynthesis"	"10"	"0"	"930.7"	"838.5"	"867.5"	"711.1"	"806.1"	"880.6"	"1047.3"	"1291.2"	"1999.3"	"4674.6"	"8263.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96PK6"	"RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2"	"24"	"14"	"25"	"14"	"669"	"69.4"	"9.67"	"4292.36"	"42.52"	"12"	"12"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00076"	"100526737; 10432"	"ENSG00000239306"	"RBM14"	"B0LM41; B3KMN4; D6RGD8; hsa:100526737; hsa:10432; O75932; Q2PYN1; Q53GV1; Q68DQ9; Q96PK5; Q96PK6"	"Ciliary landscape"	"RUNX2 regulates bone development"	"2"	"0"	"1410.3"	"1349.6"	"1350.5"	"1186.5"	"1365.0"	"1310.0"	"1650.9"	"1977.7"	"2680.8"	"4045.4"	"5793.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q05639"	"Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1"	"24"	"9"	"22"	"1"	"463"	"50.4"	"9.03"	"3642.07"	"42.38"	"7"	"9"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03143, Pf03144"	"1917"	"ENSG00000101210"	"EEF1A2"	"B5BUF3; E1P5J1; hsa:1917; P54266; Q05639; Q0VGC7"	"Translation factors"	"Eukaryotic Translation Elongation"	"2"	"0"	"66.2"	"59.1"	"84.8"	"61.3"	"59.4"	"65.7"	"78.8"	"109.9"	"294.3"	"509.4"	"551.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5VTR2"	"E3 ubiquitin-protein ligase BRE1A OS=Homo sapiens OX=9606 GN=RNF20 PE=1 SV=2"	"11"	"11"	"20"	"8"	"975"	"113.6"	"5.94"	"3674.92"	"42.33"	"9"	"11"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00097"	"56254"	"ENSG00000155827"	"RNF20"	"A7MCT5; hsa:56254; Q2TB34; Q5VTR2; Q69YL5; Q6P527; Q8N3J4; Q96JD3; Q9H9Y7; Q9HA51; Q9NUR4; Q9NWQ3; Q9NX83"	"ATM signaling in development and disease"	"E3 ubiquitin ligases ubiquitinate target proteins; RHOBTB1 GTPase cycle"	"3"	"3"	"522.4"	"505.1"	"572.2"	"459.6"	"576.6"	"540.4"	"660.0"	"889.7"	"2314.0"	"4394.5"	"6313.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P39748"	"Flap endonuclease 1 OS=Homo sapiens OX=9606 GN=FEN1 PE=1 SV=1"	"32"	"10"	"23"	"10"	"380"	"42.6"	"8.62"	"4655.36"	"42.23"	"9"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00752, Pf00867"	"2237"	"ENSG00000168496"	"FEN1"	"hsa:2237; P39748"	"Base excision repair; DNA repair pathways, full network"	"HDR through MMEJ (alt-NHEJ); Early Phase of HIV Life Cycle; POLB-Dependent Long Patch Base Excision Repair; PCNA-Dependent Long Patch Base Excision Repair; Removal of the Flap Intermediate; Removal of the Flap Intermediate from the C-strand"	"8"	"0"	"1559.7"	"1200.5"	"1597.0"	"1401.4"	"1501.2"	"1582.7"	"1941.9"	"2174.6"	"5417.4"	"7838.7"	"7251.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95831"	"Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1"	"20"	"9"	"20"	"9"	"613"	"66.9"	"8.95"	"4398.45"	"42.21"	"9"	"9"	"cell organization and biogenesis;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00070, Pf14721"	"9131"	"ENSG00000156709"	"AIFM1"	"A4QPB4; B1ALN1; B2RB08; D3DTE9; E9PRR0; hsa:9131; O95831; Q1L6K4; Q1L6K6; Q2QKE4; Q5JUZ7; Q6I9X6; Q9Y3I3; Q9Y3I4"	"Apoptosis modulation and signaling; Nanomaterial induced apoptosis; Apoptosis modulation by HSP70"	""	"3"	"0"	"416.7"	"464.6"	"475.5"	"463.4"	"486.4"	"525.2"	"571.6"	"673.5"	"1385.6"	"3957.5"	"7380.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UNX4"	"WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1"	"12"	"10"	"22"	"10"	"943"	"106.0"	"6.64"	"4386.06"	"41.98"	"9"	"9"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00400, Pf04003, Pf12894"	"10885"	"ENSG00000065183"	"WDR3"	"hsa:10885; Q9UNX4"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"676.3"	"656.1"	"710.5"	"625.0"	"731.2"	"714.1"	"789.3"	"1246.7"	"4840.3"	"5855.6"	"5267.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UEY8"	"Gamma-adducin OS=Homo sapiens OX=9606 GN=ADD3 PE=1 SV=1"	"17"	"10"	"18"	"9"	"706"	"79.1"	"6.32"	"2839.06"	"41.95"	"5"	"10"	"cell organization and biogenesis"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00596"	"120"	"ENSG00000148700"	"ADD3"	"D3DRA8; hsa:120; O43243; Q5VU09; Q92773; Q9UEY7; Q9UEY8"	""	"Miscellaneous transport and binding events; RHOD GTPase cycle; RHOF GTPase cycle"	"3"	"0"	"411.6"	"308.5"	"440.3"	"386.3"	"433.7"	"456.5"	"482.1"	"620.4"	"2122.4"	"2546.3"	"2861.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13263"	"Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5"	"12"	"8"	"16"	"8"	"835"	"88.5"	"5.77"	"3144.63"	"41.51"	"5"	"8"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00628, Pf00643, Pf14634"	"10155"	"ENSG00000130726"	"TRIM28"	"hsa:10155; O00677; Q13263; Q7Z632; Q93040; Q96IM1"	"Corticotropin-releasing hormone signaling pathway; Mesodermal commitment pathway; ATM signaling in development and disease"	"HCMV Early Events; SUMOylation of transcription cofactors; Generic Transcription Pathway"	"6"	"0"	"441.4"	"411.5"	"492.9"	"464.4"	"484.3"	"483.7"	"573.2"	"679.2"	"1217.5"	"3161.6"	"7119.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q71DI3"	"Histone H3.2 OS=Homo sapiens OX=9606 GN=H3C15 PE=1 SV=3"	"55"	"8"	"24"	"1"	"136"	"15.4"	"11.27"	"4000.75"	"41.47"	"7"	"8"	"cell organization and biogenesis"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125"	"126961; 333932; 653604"	"ENSG00000183598; ENSG00000203811; ENSG00000203852"	"H3C13; H3C14; H3C15"	"A2BDF6; A6NFS4; hsa:126961; hsa:333932; hsa:653604; Q6B053; Q71DI3"	"Histone modifications; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma"	"Meiotic recombination; Amyloid fiber formation; HCMV Late Events; RUNX1 regulates transcription of genes involved in differentiation of HSCs; HCMV Early Events; Transcriptional regulation by small RNAs; B-WICH complex positively regulates rRNA expression; Formation of the beta-catenin:TCF transactivating complex; Oxidative Stress Induced Senescence; HDACs deacetylate histones; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Pre-NOTCH Transcription and Translation; Senescence-Associated Secretory Phenotype (SASP); RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; HATs acetylate histones; RNA Polymerase I Promoter Escape; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Condensation of Prophase Chromosomes; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis; RMTs methylate histone arginines; Interleukin-7 signaling; Factors involved in megakaryocyte development and platelet production; HDMs demethylate histones; PKMTs methylate histone lysines"	"36"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52292"	"Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1"	"25"	"11"	"22"	"11"	"529"	"57.8"	"5.40"	"3812.91"	"41.35"	"9"	"9"	"DNA metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00514, Pf01749, Pf16186"	"3838"	"ENSG00000182481"	"KPNA2"	"B9EJD6; hsa:3838; P52292; Q53YE3; Q6NVW7; Q9BRU5"	""	"ISG15 antiviral mechanism; NS1 Mediated Effects on Host Pathways; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Estrogen-dependent gene expression; SARS-CoV-1 activates/modulates innate immune responses; Sensing of DNA Double Strand Breaks; CaMK IV-mediated phosphorylation of CREB; CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde"	"8"	"0"	"776.6"	"664.6"	"808.1"	"712.5"	"800.7"	"811.4"	"890.7"	"1107.1"	"1937.4"	"3953.4"	"6502.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P56192"	"Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2"	"15"	"9"	"17"	"9"	"900"	"101.1"	"6.16"	"2774.79"	"41.21"	"7"	"9"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00043, Pf00458, Pf09334, Pf18485, Pf19303"	"4141"	"ENSG00000166986"	"MARS1"	"B3KVK7; hsa:4141; P56192; Q14895; Q53H14; Q96A15; Q96BZ0; Q9NSE0"	""	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"2"	"0"	"364.2"	"323.3"	"359.4"	"318.6"	"381.5"	"318.4"	"407.1"	"528.9"	"1217.5"	"3130.6"	"4684.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11387"	"DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2"	"14"	"11"	"26"	"11"	"765"	"90.7"	"9.31"	"5196.15"	"41.14"	"10"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf01028, Pf02919, Pf14370"	"7150"	"ENSG00000198900"	"TOP1"	"A8KA78; E1P5W3; hsa:7150; O43256; P11387; Q12855; Q12856; Q15610; Q5TFY3; Q9UJN0"	"Ebola virus infection in host; 15q25 copy number variation"	"SUMOylation of DNA replication proteins"	"3"	"0"	"1049.7"	"858.7"	"984.2"	"847.2"	"975.3"	"1056.5"	"1263.2"	"1394.0"	"3884.2"	"5755.7"	"6593.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96BP3"	"Peptidylprolyl isomerase domain and WD repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=PPWD1 PE=1 SV=1"	"20"	"9"	"16"	"9"	"646"	"73.5"	"7.15"	"3140.58"	"41.10"	"7"	"9"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00160, Pf00400"	"23398"	"ENSG00000113593"	"PPWD1"	"B4DWR9; hsa:23398; Q15002; Q7KZ89; Q96BP3"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"254.4"	"260.7"	"281.9"	"246.8"	"289.1"	"301.5"	"338.2"	"423.9"	"992.8"	"3601.2"	"5750.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00291"	"Huntingtin-interacting protein 1 OS=Homo sapiens OX=9606 GN=HIP1 PE=1 SV=5"	"14"	"11"	"19"	"11"	"1037"	"116.1"	"5.30"	"3498.57"	"40.87"	"9"	"10"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf01608, Pf07651, Pf16515"	"3092"	"ENSG00000127946"	"HIP1"	"B4E3I7; E7ES17; hsa:3092; O00291; O00328; Q2TB58; Q8TDL4; V5LU97"	"DYRK1A involvement regarding cell proliferation in brain development; 5q35 copy number variation"	"Clathrin-mediated endocytosis; ALK mutants bind TKIs; Signaling by ALK fusions and activated point mutants"	"5"	"0"	"216.0"	"204.2"	"264.0"	"224.4"	"292.1"	"298.4"	"312.9"	"555.0"	"3199.2"	"6273.2"	"9629.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q04837"	"Single-stranded DNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SSBP1 PE=1 SV=1"	"43"	"6"	"16"	"6"	"148"	"17.2"	"9.60"	"2855.43"	"40.85"	"4"	"6"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00436"	"6742"	"ENSG00000106028; ENSG00000262771"	"SSBP1"	"hsa:6742; Q04837"	""	"Transcriptional activation of mitochondrial biogenesis"	"1"	"0"	"558.4"	"608.5"	"542.4"	"475.2"	"543.1"	"601.6"	"685.7"	"879.6"	"1278.8"	"2563.1"	"3675.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43175"	"D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4"	"19"	"8"	"21"	"8"	"533"	"56.6"	"6.71"	"3592.39"	"40.81"	"7"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;developmental processes;other biological processes"	"cytosol"	"other molecular function"	"Pf00389, Pf02826, Pf19304"	"26227"	"ENSG00000092621"	"PHGDH"	"B2RD08; hsa:26227; O43175; Q5SZU3; Q9BQ01"	"Trans-sulfuration, one-carbon metabolism and related pathways; Clear cell renal cell carcinoma pathways; Neuroinflammation and glutamatergic signaling; Amino acid metabolism in triple-negative breast cancer cells"	"Serine biosynthesis"	"5"	"0"	"607.1"	"602.7"	"611.8"	"585.1"	"677.0"	"674.0"	"933.6"	"1449.0"	"2389.0"	"4814.0"	"7400.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43172"	"U4/U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2"	"21"	"10"	"19"	"10"	"522"	"58.4"	"7.42"	"4394.63"	"40.58"	"9"	"8"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00400, Pf08799"	"9128"	"ENSG00000136875"	"PRPF4"	"hsa:9128; O43172; O43445; O43864; Q5T1M8; Q96DG2; Q96IK4"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"838.7"	"648.1"	"886.2"	"766.8"	"800.8"	"745.2"	"894.9"	"1064.5"	"1594.6"	"2541.5"	"3615.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63279"	"SUMO-conjugating enzyme UBC9 OS=Homo sapiens OX=9606 GN=UBE2I PE=1 SV=1"	"58"	"9"	"19"	"9"	"158"	"18.0"	"8.66"	"4943.11"	"40.48"	"8"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00179"	"7329"	"ENSG00000103275"	"UBE2I"	"D3DU69; hsa:7329; P50550; P63279; Q15698; Q59GX1; Q86VB3"	"Androgen receptor signaling pathway; TAR syndrome"	"SUMOylation of RNA binding proteins; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of DNA replication proteins; Postmitotic nuclear pore complex (NPC) reformation; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; Meiotic synapsis; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; SUMOylation of intracellular receptors; Processing of DNA double-strand break ends; Vitamin D (calciferol) metabolism; SUMOylation of transcription factors; Formation of Incision Complex in GG-NER; Negative regulation of activity of TFAP2 (AP-2) family transcription factors; Maturation of nucleoprotein; SUMOylation of immune response proteins; SUMOylation of nuclear envelope proteins; Maturation of nucleoprotein; SUMO is transferred from E1 to E2 (UBE2I, UBC9)"	"25"	"0"	"731.8"	"614.9"	"861.2"	"782.7"	"801.3"	"807.7"	"1277.0"	"2091.7"	"4014.0"	"6377.2"	"9324.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15428"	"Splicing factor 3A subunit 2 OS=Homo sapiens OX=9606 GN=SF3A2 PE=1 SV=2"	"19"	"6"	"17"	"6"	"464"	"49.2"	"9.64"	"4093.29"	"40.41"	"3"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf12874, Pf16835"	"8175"	"ENSG00000104897"	"SF3A2"	"B2RBU1; D6W605; hsa:8175; O75245; Q15428"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"427.8"	"386.1"	"372.4"	"340.5"	"436.1"	"424.9"	"488.4"	"561.6"	"1449.8"	"4082.3"	"6745.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16836"	"Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=HADH PE=1 SV=3"	"27"	"10"	"24"	"10"	"314"	"34.3"	"8.85"	"3770.35"	"39.90"	"8"	"10"	"other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00725, Pf02737"	"3033"	"ENSG00000138796"	"HADH"	"hsa:3033; J3KQ17; O00324; O00397; O00753; Q16836; Q4W5B4"	"Fatty acid beta-oxidation; Fatty acid biosynthesis; Mitochondrial long chain fatty acid beta-oxidation; Amino acid metabolism; IL-18 signaling pathway; Mitochondrial fatty acid oxidation disorders"	"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA; Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of butanoyl-CoA to acetyl-CoA; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA"	"11"	"0"	"641.4"	"506.2"	"691.6"	"699.1"	"740.6"	"703.5"	"838.2"	"1021.7"	"2390.5"	"6193.1"	"9057.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11310"	"Medium-chain specific acyl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ACADM PE=1 SV=1"	"32"	"9"	"14"	"9"	"421"	"46.6"	"8.37"	"2386.11"	"39.90"	"5"	"9"	"other metabolic processes;stress response;developmental processes;other biological processes"	"other membranes;mitochondrion;other cell component"	"other molecular function"	"Pf00441, Pf02770, Pf02771"	"34"	"ENSG00000117054"	"ACADM"	"hsa:34; P11310; Q5T4U4; Q9NYF1"	"Fatty acid beta-oxidation; PPAR-alpha pathway; Nuclear receptors meta-pathway; Mitochondrial long chain fatty acid beta-oxidation; Amino acid metabolism; PPAR signaling pathway; Mitochondrial fatty acid oxidation disorders; Female steroid hormones in cardiomyocyte energy metabolism; Sudden infant death syndrome (SIDS) susceptibility pathways"	"PPARA activates gene expression; mitochondrial fatty acid beta-oxidation of unsaturated fatty acids; Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA"	"13"	"0"	"221.6"	"203.6"	"237.8"	"227.5"	"196.3"	"246.2"	"271.6"	"304.3"	"1163.6"	"3763.4"	"5990.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5JWF2"	"Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas OS=Homo sapiens OX=9606 GN=GNAS PE=1 SV=2"	"10"	"8"	"14"	"8"	"1037"	"111.0"	"5.03"	"1628.57"	"39.88"	"5"	"8"	"cell adhesion;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00503"	"2778"	"ENSG00000087460"	"GNAS"	"A2A2S3; E1P5G3; O75684; O75685; Q5JW67; Q5JWF1; Q5JWF2; Q9NY42"	"Thyroid stimulating hormone (TSH) signaling pathway; Endothelin pathways; Corticotropin-releasing hormone signaling pathway; Common pathways underlying drug addiction; Myometrial relaxation and contraction pathways; G protein signaling pathways; Thermogenesis; Hippo signaling regulation pathways; Purinergic signaling; GPR143 in melanocytes and retinal pigment epithelium cells; Prostaglandin and leukotriene metabolism in senescence ; Primary ovarian insufficiency; Prostaglandin and leukotriene metabolism in senescence ; Calcium regulation in cardiac cells; Estrogen signaling pathway; Serotonin receptor 4/6/7 and NR3C signaling"	"G alpha (i) signalling events; G alpha (z) signalling events; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Prostacyclin signalling through prostacyclin receptor; Glucagon-type ligand receptors; Vasopressin regulates renal water homeostasis via Aquaporins; PKA activation in glucagon signalling; Hedgehog 'off' state"	"28"	"0"	"342.1"	"261.2"	"375.0"	"319.7"	"332.3"	"324.6"	"389.4"	"473.2"	"1066.3"	"3339.9"	"5973.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P28370"	"Probable global transcription activator SNF2L1 OS=Homo sapiens OX=9606 GN=SMARCA1 PE=1 SV=2"	"13"	"14"	"26"	"8"	"1054"	"122.5"	"8.09"	"4635.43"	"39.87"	"13"	"13"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf09110, Pf09111"	"6594"	"ENSG00000102038"	"SMARCA1"	"hsa:6594; P28370; Q5JV41; Q5JV42"	"Nuclear receptors meta-pathway; Rett syndrome causing genes"	""	"2"	"6"	"1030.8"	"938.9"	"1061.2"	"908.6"	"1010.6"	"1058.0"	"1302.0"	"1736.5"	"3665.2"	"5226.3"	"5237.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UH65"	"Switch-associated protein 70 OS=Homo sapiens OX=9606 GN=SWAP70 PE=1 SV=1"	"19"	"11"	"24"	"11"	"585"	"69.0"	"5.87"	"4653.22"	"39.81"	"11"	"10"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00169"	"23075"	"ENSG00000133789"	"SWAP70"	"D3DQV1; hsa:23075; O75135; Q7LCY6; Q9P061; Q9P0Z8; Q9UH65"	""	"RAC1 GTPase cycle; RAC3 GTPase cycle; RAC2 GTPase cycle"	"3"	"0"	"179.4"	"200.0"	"237.6"	"195.4"	"252.0"	"289.0"	"433.3"	"1082.6"	"3199.6"	"5904.6"	"7563.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15019"	"Septin-2 OS=Homo sapiens OX=9606 GN=SEPTIN2 PE=1 SV=1"	"33"	"9"	"19"	"9"	"361"	"41.5"	"6.60"	"3273.04"	"39.77"	"7"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00735"	"4735"	"ENSG00000168385"	"SEPTIN2"	"B4DGE8; hsa:4735; Q14132; Q15019; Q53QU3; Q8IUK9; Q96CB0"	"2q37 copy number variation syndrome"	"Anchoring of the basal body to the plasma membrane"	"2"	"0"	"910.8"	"795.3"	"997.3"	"840.5"	"981.9"	"980.3"	"1221.2"	"1763.8"	"4120.4"	"6154.9"	"8228.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30419"	"Glycylpeptide N-tetradecanoyltransferase 1 OS=Homo sapiens OX=9606 GN=NMT1 PE=1 SV=2"	"22"	"9"	"19"	"6"	"496"	"56.8"	"7.80"	"3475.26"	"39.46"	"8"	"9"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf01233, Pf02799"	"4836"	"ENSG00000136448"	"NMT1"	"A8K7C1; hsa:4836; P30419; Q9UE09"	""	"Inactivation, recovery and regulation of the phototransduction cascade; Late Phase of HIV Life Cycle; Activation, myristolyation of BID and translocation to mitochondria"	"3"	"3"	"445.5"	"412.3"	"479.3"	"430.3"	"486.9"	"479.3"	"568.6"	"821.6"	"3040.0"	"4600.7"	"4491.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99543"	"DnaJ homolog subfamily C member 2 OS=Homo sapiens OX=9606 GN=DNAJC2 PE=1 SV=4"	"19"	"9"	"17"	"9"	"621"	"72.0"	"8.70"	"3114.42"	"39.40"	"8"	"8"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"translation activity;other molecular function"	"Pf00226, Pf00249, Pf16717"	"27000"	"ENSG00000105821"	"DNAJC2"	"A4VCI0; hsa:27000; Q99543; Q9BVX1"	""	"Regulation of HSF1-mediated heat shock response"	"1"	"0"	"490.8"	"449.7"	"510.6"	"434.8"	"502.5"	"487.2"	"596.6"	"820.4"	"2028.7"	"3499.3"	"4261.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6NVY1"	"3-hydroxyisobutyryl-CoA hydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=HIBCH PE=1 SV=2"	"27"	"10"	"23"	"10"	"386"	"43.5"	"8.19"	"4789.29"	"39.27"	"9"	"8"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf16113"	"26275"	"ENSG00000198130"	"HIBCH"	"D3DPI4; hsa:26275; Q53GA8; Q53GF2; Q53RF7; Q53TC6; Q6NVY1; Q92931; Q9BS94"	"Amino acid metabolism"	"Branched-chain amino acid catabolism"	"2"	"0"	"183.9"	"162.5"	"243.4"	"203.5"	"227.4"	"217.6"	"260.2"	"408.6"	"2507.7"	"6056.4"	"9468.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86V81"	"THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3"	"48"	"8"	"11"	"8"	"257"	"26.9"	"11.15"	"1460.89"	"39.27"	"4"	"7"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf13865"	"10189"	""	"ALYREF"	"hsa:10189; O43672; Q86V81"	""	"mRNA Splicing - Major Pathway; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"7"	"0"	"765.9"	"690.9"	"723.1"	"660.3"	"754.9"	"789.9"	"914.7"	"1037.4"	"1350.8"	"2175.4"	"3623.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4Z0"	"U6 snRNA-associated Sm-like protein LSm4 OS=Homo sapiens OX=9606 GN=LSM4 PE=1 SV=1"	"28"	"6"	"21"	"6"	"139"	"15.3"	"9.99"	"4459.57"	"39.16"	"6"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01423"	"25804"	"ENSG00000130520"	"LSM4"	"hsa:25804; Q9Y4Z0"	"Ciliary landscape"	"mRNA Splicing - Major Pathway; mRNA decay by 5' to 3' exoribonuclease"	"3"	"0"	"648.9"	"600.2"	"725.8"	"697.4"	"812.4"	"764.6"	"853.5"	"1036.1"	"1513.7"	"2777.0"	"5894.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06576"	"ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3"	"16"	"7"	"19"	"7"	"529"	"56.5"	"5.40"	"4319.98"	"39.13"	"6"	"7"	"other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;mitochondrion;other cell component"	"signal transduction activity or receptor binding;transporter activity;other molecular function"	"Pf00006, Pf02874"	"506"	"ENSG00000110955"	"ATP5F1B"	"A8K4X0; hsa:506; P06576; Q14283"	"Electron transport chain: OXPHOS system in mitochondria; 7q11.23 copy number variation syndrome; Oxidative phosphorylation"	"Transcriptional activation of mitochondrial biogenesis; Mitochondrial protein import; Cristae formation; Formation of ATP by chemiosmotic coupling"	"7"	"0"	"364.2"	"385.1"	"403.5"	"365.8"	"422.3"	"400.4"	"484.6"	"655.7"	"1539.1"	"4099.3"	"7130.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61201"	"COP9 signalosome complex subunit 2 OS=Homo sapiens OX=9606 GN=COPS2 PE=1 SV=1"	"22"	"9"	"19"	"9"	"443"	"51.6"	"5.53"	"3578.60"	"38.99"	"9"	"9"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01399"	"9318"	"ENSG00000166200"	"COPS2"	"hsa:9318; O88950; P61201; Q15647; Q6FGP4; Q9BY54; Q9R249; Q9UNI2; Q9UNQ5"	"Ciliary landscape"	"Neddylation; Formation of TC-NER Pre-Incision Complex; Cargo recognition for clathrin-mediated endocytosis; RHOBTB1 GTPase cycle; DNA Damage Recognition in GG-NER"	"6"	"0"	"204.0"	"220.0"	"242.6"	"204.6"	"248.2"	"305.9"	"451.9"	"848.1"	"1866.7"	"4811.6"	"8804.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P99999"	"Cytochrome c OS=Homo sapiens OX=9606 GN=CYCS PE=1 SV=2"	"56"	"7"	"22"	"7"	"105"	"11.7"	"9.57"	"4223.46"	"38.99"	"7"	"7"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"other membranes;cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf00034"	"54205"	"ENSG00000172115"	"CYCS"	"A4D166; B2R4I1; hsa:54205; P00001; P99999; Q6NUR2; Q6NX69; Q96BV4"	"miRNA regulation of DNA damage response; Apoptosis modulation and signaling; Alzheimer's disease and miRNA effects; AGE/RAGE pathway; Parkinson's disease pathway; Nanomaterial induced apoptosis; Apoptosis; Fas ligand pathway and stress induction of heat shock proteins; Apoptosis modulation by HSP70; VEGFA-VEGFR2 signaling; Oxidative damage response; NO/cGMP/PKG mediated neuroprotection; Chromosomal and microsatellite instability in colorectal cancer ; Non-small cell lung cancer; Acute viral myocarditis; Nonalcoholic fatty liver disease; Measles virus infection; Small cell lung cancer; Hepatitis B infection; IL-18 signaling pathway; Pleural mesothelioma; Complement system in neuronal development and plasticity; Alzheimer's disease; DNA damage response"	"Respiratory electron transport; Detoxification of Reactive Oxygen Species; Transcriptional activation of mitochondrial biogenesis; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1; Activation of caspases through apoptosome-mediated cleavage; SMAC (DIABLO) binds to IAPs ; SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes ; Regulation of the apoptosome activity; Release of apoptotic factors from the mitochondria; Pyroptosis"	"36"	"0"	"2075.1"	"2099.4"	"1760.1"	"1008.3"	"1475.2"	"1873.0"	"2432.0"	"1963.8"	"2002.8"	"2745.3"	"3358.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60934"	"Nibrin OS=Homo sapiens OX=9606 GN=NBN PE=1 SV=1"	"17"	"11"	"17"	"11"	"754"	"84.9"	"6.90"	"3141.69"	"38.78"	"7"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00498, Pf08599, Pf16508"	"4683"	"ENSG00000104320"	"NBN"	"B2R626; B2RNC5; hsa:4683; O60672; O60934; Q32NF7; Q53FM6; Q63HR6; Q7LDM2"	"miRNA regulation of DNA damage response; Homologous recombination; DDX1 as a regulatory component of the Drosha microprocessor; ATM signaling in development and disease ; Breast cancer pathway; DNA repair pathways, full network; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; Primary ovarian insufficiency; DNA damage response"	"Resolution of D-loop Structures through Holliday Junction Intermediates; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; Meiotic recombination; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; DNA Damage/Telomere Stress Induced Senescence; Nonhomologous End-Joining (NHEJ); HDR through MMEJ (alt-NHEJ); Sensing of DNA Double Strand Breaks"	"29"	"0"	"384.4"	"323.0"	"430.4"	"371.4"	"411.6"	"433.5"	"510.0"	"720.0"	"1673.6"	"3980.0"	"7202.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61247"	"40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2"	"39"	"12"	"26"	"12"	"264"	"29.9"	"9.73"	"4231.66"	"38.72"	"10"	"10"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01015"	"6189"	"ENSG00000145425"	"RPS3A"	"B2R4D4; D3DP05; hsa:6189; P33443; P49241; P61247"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"1653.2"	"1616.7"	"1519.1"	"1384.3"	"1679.4"	"1591.8"	"1919.9"	"2228.0"	"3002.4"	"5652.7"	"8430.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01105"	"Protein SET OS=Homo sapiens OX=9606 GN=SET PE=1 SV=3"	"28"	"6"	"17"	"6"	"290"	"33.5"	"4.32"	"3371.73"	"38.63"	"5"	"6"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00956"	"6418"	"ENSG00000119335"	"SET"	"A5A5H4; A6NGV1; B4DUE2; hsa:6418; Q01105; Q15541; Q5VXV1; Q5VXV2; Q6FHZ5"	"Histone modifications; VEGFA-VEGFR2 signaling"	"HuR (ELAVL1) binds and stabilizes mRNA; Condensation of Prophase Chromosomes"	"4"	"0"	"479.7"	"665.0"	"462.3"	"431.5"	"510.3"	"559.2"	"752.3"	"1092.0"	"1559.6"	"2176.0"	"2919.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51610"	"Host cell factor 1 OS=Homo sapiens OX=9606 GN=HCFC1 PE=1 SV=2"	"7"	"11"	"21"	"11"	"2035"	"208.6"	"7.46"	"4073.46"	"38.59"	"10"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf01344, Pf13415"	"3054"	"ENSG00000172534"	"HCFC1"	"hsa:3054; P51610; Q6P4G5"	"Mitochondrial gene expression; Pleural mesothelioma"	"UCH proteinases; Formation of WDR5-containing histone-modifying complexes; Transcriptional activation of mitochondrial biogenesis; HATs acetylate histones"	"6"	"0"	"926.6"	"831.0"	"900.3"	"809.3"	"895.9"	"916.3"	"1091.9"	"1247.4"	"1818.2"	"3214.7"	"5210.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BY44"	"Eukaryotic translation initiation factor 2A OS=Homo sapiens OX=9606 GN=EIF2A PE=1 SV=3"	"24"	"10"	"21"	"10"	"585"	"64.9"	"8.87"	"3760.69"	"38.57"	"9"	"10"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;translational apparatus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf08662"	"83939"	"ENSG00000144895"	"EIF2A"	"A8MPS6; B4DF96; B4DQ14; D3DNI9; hsa:83939; Q5QTR2; Q7Z4E9; Q8NFM1; Q96EW9; Q96K81; Q9BY44"	"Photodynamic therapy-induced unfolded protein response; VEGFA-VEGFR2 signaling; 7q11.23 copy number variation syndrome"	""	"3"	"0"	"538.0"	"477.3"	"519.5"	"472.8"	"537.5"	"525.2"	"620.3"	"738.9"	"1498.0"	"2895.5"	"3323.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92576"	"PHD finger protein 3 OS=Homo sapiens OX=9606 GN=PHF3 PE=1 SV=3"	"6"	"9"	"17"	"9"	"2039"	"229.3"	"6.96"	"2720.22"	"38.52"	"7"	"9"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00628, Pf07500, Pf07744"	"23469"	"ENSG00000118482"	"PHF3"	"A3KFI8; hsa:23469; Q14CR5; Q5CZI1; Q5T1T6; Q92576; Q9NQ16; Q9UI45"	""	""	"0"	"0"	"303.7"	"300.2"	"366.9"	"318.4"	"376.1"	"364.1"	"408.1"	"483.7"	"801.8"	"1409.2"	"1817.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TCS8"	"Polyribonucleotide nucleotidyltransferase 1, mitochondrial OS=Homo sapiens OX=9606 GN=PNPT1 PE=1 SV=2"	"18"	"10"	"18"	"10"	"783"	"85.9"	"7.77"	"3521.05"	"38.42"	"8"	"10"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"other membranes;cytosol;mitochondrion;ER/Golgi;translational apparatus;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf01138, Pf03725, Pf03726"	"87178"	"ENSG00000138035"	"PNPT1"	"hsa:87178; Q53SU0; Q68CN1; Q7Z7D1; Q8IWX1; Q8TCS8; Q96T05; Q9BRU3; Q9BVX0"	"Pyrimidine metabolism; miRNA degrading enzymes"	""	"2"	"0"	"288.5"	"284.0"	"320.8"	"305.3"	"327.0"	"295.9"	"403.6"	"480.0"	"1019.6"	"1944.6"	"2948.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52209"	"6-phosphogluconate dehydrogenase, decarboxylating OS=Homo sapiens OX=9606 GN=PGD PE=1 SV=3"	"23"	"8"	"15"	"8"	"483"	"53.1"	"7.23"	"2804.02"	"38.37"	"5"	"8"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf00393, Pf03446"	"5226"	"ENSG00000142657"	"PGD"	"A8K2Y9; B4DQJ8; hsa:5226; P52209; Q9BWD8"	"Pentose phosphate metabolism; Nuclear receptors meta-pathway; NRF2 pathway; VEGFA-VEGFR2 signaling; Metabolic reprogramming in colon cancer"	"NFE2L2 regulates pentose phosphate pathway genes; Pentose phosphate pathway"	"7"	"0"	"299.9"	"202.2"	"334.1"	"275.1"	"298.4"	"258.7"	"351.2"	"443.6"	"1040.3"	"3330.2"	"6433.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BZJ0"	"Crooked neck-like protein 1 OS=Homo sapiens OX=9606 GN=CRNKL1 PE=1 SV=4"	"13"	"10"	"17"	"10"	"848"	"100.4"	"8.00"	"2925.58"	"38.19"	"7"	"10"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf02184"	"51340"	"ENSG00000101343"	"CRNKL1"	"A8K9T4; hsa:51340; Q5JY64; Q8WYI5; Q9BZI9; Q9BZJ0; Q9BZJ1; Q9BZJ2; Q9GZW7; Q9H8F8; Q9NQH5; Q9NYD8"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"370.5"	"387.2"	"455.3"	"415.3"	"459.9"	"411.9"	"511.6"	"619.7"	"1719.6"	"4004.7"	"7301.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5UIP0"	"Telomere-associated protein RIF1 OS=Homo sapiens OX=9606 GN=RIF1 PE=1 SV=2"	"5"	"9"	"18"	"9"	"2472"	"274.3"	"5.52"	"3637.98"	"38.16"	"9"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	""	"Pf12231"	"55183"	"ENSG00000080345"	"RIF1"	"A6NC27; C9JBR1; hsa:55183; Q5H9R3; Q5UIP0; Q5UIP2; Q66YK6; Q6PRU2; Q8TE94; Q99772; Q9H830; Q9H9B9; Q9NVP5; Q9Y4R4"	"ATM signaling in development and disease ; 10q11.21q11.23 copy number variation syndrome"	"Nonhomologous End-Joining (NHEJ)"	"3"	"0"	"528.5"	"442.4"	"619.4"	"545.1"	"572.1"	"573.0"	"625.9"	"724.8"	"1755.4"	"2598.2"	"3267.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15717"	"ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2"	"28"	"8"	"21"	"8"	"326"	"36.1"	"9.17"	"3503.78"	"38.10"	"7"	"8"	"cell organization and biogenesis;transport;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"1994"	"ENSG00000066044"	"ELAVL1"	"B4DVB8; hsa:1994; Q15717; Q53XN6; Q9BTT1"	"AMP-activated protein kinase signaling; Endoderm differentiation; Pre-implantation embryo; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Gastrin signaling pathway; IL-18 signaling pathway; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; 1p36 copy number variation syndrome"	"HuR (ELAVL1) binds and stabilizes mRNA"	"10"	"0"	"776.4"	"979.5"	"875.6"	"765.0"	"783.0"	"653.9"	"957.8"	"1371.6"	"2018.9"	"3402.8"	"5053.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00267"	"Transcription elongation factor SPT5 OS=Homo sapiens OX=9606 GN=SUPT5H PE=1 SV=1"	"12"	"12"	"22"	"12"	"1087"	"120.9"	"5.06"	"4759.15"	"38.05"	"11"	"9"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00467, Pf03439, Pf11942"	"6829"	"ENSG00000196235"	"SUPT5H"	"hsa:6829; O00267; O43279; Q59G52; Q99639"	"Initiation of transcription and translation elongation at the HIV-1 LTR; mRNA processing"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE"	"20"	"0"	"1314.4"	"1466.3"	"1319.2"	"1243.3"	"1350.0"	"1356.9"	"1642.7"	"2014.6"	"2517.1"	"3567.4"	"4668.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05198"	"Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3"	"33"	"9"	"22"	"9"	"315"	"36.1"	"5.08"	"3110.26"	"37.92"	"8"	"9"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf00575, Pf07541"	"1965"	"ENSG00000134001"	"EIF2S1"	"hsa:1965; P05198"	"Translation factors; Alzheimer's disease and miRNA effects; Brain-derived neurotrophic factor (BDNF) signaling pathway; Ebola virus infection in host; Nonalcoholic fatty liver disease; Measles virus infection; Unfolded protein response; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell; Alzheimer's disease"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; ABC-family proteins mediated transport; Response of EIF2AK1 (HRI) to heme deficiency; PERK regulates gene expression; Recycling of eIF2:GDP; Response of EIF2AK4 (GCN2) to amino acid deficiency"	"19"	"0"	"503.4"	"528.4"	"500.8"	"461.5"	"520.0"	"575.9"	"655.0"	"1182.7"	"4746.2"	"5141.1"	"5379.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55081"	"Microfibrillar-associated protein 1 OS=Homo sapiens OX=9606 GN=MFAP1 PE=1 SV=2"	"21"	"10"	"22"	"10"	"439"	"51.9"	"4.98"	"4088.49"	"37.89"	"9"	"9"	"RNA metabolism OR transcription;other metabolic processes"	"extracellular matrix;cytoskeleton;nucleus"	""	"Pf06991"	"4236"	"ENSG00000140259"	"MFAP1"	"hsa:4236; P55081; Q86TG6"	"Canonical and non-canonical Notch signaling; Ciliary landscape"	"mRNA Splicing - Major Pathway"	"3"	"0"	"1217.8"	"1129.6"	"1291.1"	"1177.6"	"1258.9"	"1308.9"	"1439.5"	"1570.1"	"1834.4"	"3287.6"	"4753.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96T58"	"Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1"	"4"	"10"	"17"	"10"	"3664"	"402.0"	"7.64"	"3555.27"	"37.85"	"7"	"10"	"signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf07744"	"23013"	"ENSG00000065526"	"SPEN"	"hsa:23013; Q96T58; Q9H9A8; Q9NWH5; Q9UQ01; Q9Y556"	"Notch signaling pathway"	"RHOBTB1 GTPase cycle"	"2"	"0"	"958.0"	"800.8"	"1052.0"	"973.2"	"1065.6"	"1055.7"	"1207.7"	"1288.4"	"2005.0"	"2793.2"	"3616.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14157"	"Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2"	"11"	"8"	"15"	"8"	"1087"	"114.5"	"7.11"	"2645.28"	"37.74"	"6"	"8"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	""	"Pf12478"	"9898"	"ENSG00000143569"	"UBAP2L"	"B4E0U8; hsa:9898; Q14157; Q5VU75; Q5VU76; Q9BTU3; Q9UGL2; Q9UGL3; Q9UGL4; Q9UGL5"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"600.4"	"585.5"	"652.3"	"556.4"	"626.5"	"626.9"	"738.0"	"784.5"	"1179.0"	"1965.3"	"2731.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49006"	"MARCKS-related protein OS=Homo sapiens OX=9606 GN=MARCKSL1 PE=1 SV=2"	"54"	"6"	"14"	"6"	"195"	"19.5"	"4.67"	"2365.39"	"37.67"	"4"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02063"	"65108"	"ENSG00000175130"	"MARCKSL1"	"D3DPQ0; hsa:65108; P49006; Q5TEE6; Q6NXS5"	""	""	"0"	"0"	"144.7"	"88.4"	"178.4"	"182.6"	"143.5"	"147.3"	"180.6"	"240.0"	"1758.1"	"4939.2"	"6272.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13247"	"Serine/arginine-rich splicing factor 6 OS=Homo sapiens OX=9606 GN=SRSF6 PE=1 SV=2"	"24"	"9"	"22"	"5"	"344"	"39.6"	"11.43"	"3445.31"	"37.60"	"7"	"9"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076"	"6431"	"ENSG00000124193"	"SRSF6"	"B7Z6J3; E1P5W6; hsa:6431; Q13244; Q13245; Q13247; Q96J06; Q9UJB8; Q9Y3N7"	"mRNA processing"	"RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing"	"7"	"0"	"863.9"	"706.4"	"980.4"	"900.4"	"891.3"	"827.1"	"1056.3"	"1182.1"	"1293.0"	"1575.8"	"2308.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13838"	"Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1"	"22"	"10"	"22"	"5"	"428"	"49.0"	"5.67"	"4018.31"	"37.49"	"9"	"9"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"7919"	"ENSG00000198563; ENSG00000215425; ENSG00000225073; ENSG00000225859; ENSG00000229496; ENSG00000230624; ENSG00000235439"	"DDX39B"	"B0S8C0; hsa:7919; O43496; Q0EFA1; Q13838; Q2L6F9; Q53GL9; Q5RJ64; Q5RJ66; Q5ST94; Q5STB4; Q5STB5; Q5STB7; Q5STB8; Q5STU4; Q5STU5; Q5STU6; Q5STU8; Q71V76"	""	"mRNA Splicing - Major Pathway; RHOBTB2 GTPase cycle; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"5"	"5"	"479.7"	"492.6"	"604.0"	"518.4"	"551.7"	"498.5"	"665.3"	"887.1"	"1382.4"	"2830.9"	"5519.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P42167"	"Lamina-associated polypeptide 2, isoforms beta/gamma OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2"	"25"	"9"	"19"	"3"	"454"	"50.6"	"9.38"	"4269.87"	"37.44"	"8"	"8"	""	"other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03020, Pf08198"	"7112"	"ENSG00000120802"	"TMPO"	"A2T926; hsa:7112; P42167; Q14861"	"Envelope proteins and their potential roles in EDMD physiopathology; Overlap between signal transduction pathways contributing to LMNA laminopathies"	"RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOJ GTPase cycle; RHOG GTPase cycle; RHOD GTPase cycle; RHOF GTPase cycle"	"12"	"0"	"360.7"	"343.4"	"353.6"	"324.3"	"362.5"	"389.0"	"424.3"	"469.9"	"951.8"	"1387.0"	"1501.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62318"	"Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1"	"52"	"6"	"14"	"6"	"126"	"13.9"	"10.32"	"2480.37"	"37.27"	"3"	"6"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01423"	"6634"	"ENSG00000100028"	"SNRPD3"	"B4DJP7; B5BU13; hsa:6634; P43331; P62318"	"mRNA processing"	"mRNA Splicing - Major Pathway; RNA Polymerase II Transcription Termination; SARS-CoV-2 modulates host translation machinery; snRNP Assembly; mRNA Splicing - Minor Pathway; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"8"	"0"	"560.9"	"847.8"	"649.7"	"511.7"	"607.3"	"587.9"	"716.9"	"919.8"	"1084.7"	"1723.3"	"2691.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60610"	"Protein diaphanous homolog 1 OS=Homo sapiens OX=9606 GN=DIAPH1 PE=1 SV=2"	"10"	"12"	"23"	"12"	"1272"	"141.3"	"5.41"	"4499.11"	"37.26"	"11"	"10"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf02181, Pf06346, Pf06367, Pf06371"	"1729"	"ENSG00000131504"	"DIAPH1"	"A6NF18; B7ZKW2; E9PEZ2; hsa:1729; O60610; Q17RN4; Q59FH8; Q9UC76"	"Microtubule cytoskeleton regulation; AGE/RAGE pathway; Focal adhesion; Type 2 papillary renal cell carcinoma; Regulation of actin cytoskeleton; G13 signaling pathway"	"RHOC GTPase cycle; RHOA GTPase cycle; RHO GTPases Activate Formins; RHOB GTPase cycle; RHOD GTPase cycle; RHOF GTPase cycle; Neutrophil degranulation; ERBB2 Regulates Cell Motility"	"14"	"0"	"1112.9"	"958.8"	"1192.1"	"1043.2"	"1113.8"	"1229.1"	"1383.2"	"1624.7"	"1977.4"	"2867.0"	"3803.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IX12"	"Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2"	"9"	"10"	"23"	"10"	"1150"	"132.7"	"5.76"	"4687.51"	"37.25"	"10"	"9"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02037, Pf14443, Pf14444, Pf19256, Pf19257"	"55749"	"ENSG00000060339"	"CCAR1"	"A0JLT7; A1L4P7; A8K9D4; B4DNP8; B4DRK8; hsa:55749; Q32NE3; Q5EBM3; Q5VUP6; Q6PIZ0; Q6X935; Q8IX12; Q9H8N4; Q9NVA7; Q9NVQ0; Q9NWM6"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"956.6"	"762.3"	"1027.6"	"878.0"	"1012.8"	"919.6"	"1111.5"	"1363.0"	"1894.4"	"2977.2"	"5352.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82970"	"High mobility group nucleosome-binding domain-containing protein 5 OS=Homo sapiens OX=9606 GN=HMGN5 PE=1 SV=1"	"31"	"6"	"12"	"6"	"282"	"31.5"	"4.55"	"1808.25"	"37.04"	"3"	"6"	"cell organization and biogenesis;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01101"	"79366"	"ENSG00000198157"	"HMGN5"	"hsa:79366; P82970; Q5JSL1"	""	""	"0"	"0"	"95.4"	"64.5"	"132.8"	"111.1"	"124.8"	"112.2"	"122.4"	"112.6"	"928.3"	"5437.1"	"6256.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30040"	"Endoplasmic reticulum resident protein 29 OS=Homo sapiens OX=9606 GN=ERP29 PE=1 SV=4"	"43"	"9"	"13"	"9"	"261"	"29.0"	"7.31"	"868.84"	"36.98"	"3"	"9"	"protein metabolism;other metabolic processes;transport;other biological processes"	"ER/Golgi;other cell component"	"other molecular function"	"Pf07749, Pf07912"	"10961"	"ENSG00000089248"	"ERP29"	"C9J183; hsa:10961; P30040; Q3MJC3; Q6FHT4"	""	""	"0"	"0"	"135.7"	"154.8"	"166.3"	"146.5"	"171.7"	"148.1"	"208.3"	"251.0"	"947.1"	"4831.0"	"7690.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96QC0"	"Serine/threonine-protein phosphatase 1 regulatory subunit 10 OS=Homo sapiens OX=9606 GN=PPP1R10 PE=1 SV=1"	"13"	"10"	"19"	"10"	"940"	"99.0"	"9.17"	"4499.55"	"36.89"	"8"	"9"	"transport;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00642, Pf08711"	"5514"	"ENSG00000204569; ENSG00000206489; ENSG00000227804; ENSG00000230995; ENSG00000231737; ENSG00000235291; ENSG00000238104"	"PPP1R10"	"hsa:5514; O00405; Q96QC0"	""	""	"0"	"0"	"933.4"	"630.1"	"916.1"	"823.2"	"882.6"	"892.5"	"1000.1"	"1058.4"	"1712.0"	"2550.3"	"3303.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P26641"	"Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3"	"25"	"12"	"27"	"12"	"437"	"50.1"	"6.67"	"4938.65"	"36.77"	"12"	"10"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity"	"Pf00043, Pf00647, Pf02798"	"1937"	"ENSG00000254772"	"EEF1G"	"B4DTG2; hsa:1937; P26641; Q6PJ62; Q6PK31; Q96CU2; Q9P196"	"Translation factors"	"Signaling by ALK fusions and activated point mutants; Eukaryotic Translation Elongation"	"3"	"0"	"1645.1"	"1419.9"	"1759.0"	"1571.8"	"1702.0"	"1633.5"	"2025.1"	"2304.5"	"4033.5"	"8478.7"	"12477.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99666"	"RANBP2-like and GRIP domain-containing protein 5/6 OS=Homo sapiens OX=9606 GN=RGPD5 PE=1 SV=3"	"8"	"12"	"22"	"3"	"1765"	"198.8"	"6.42"	"3383.69"	"36.69"	"9"	"11"	"transport"	"nucleus;other cell component"	""	"Pf00638, Pf01465, Pf16704"	"729540; 84220"	"ENSG00000015568; ENSG00000183054"	"RGPD5; RGPD6"	"hsa:729540; hsa:84220; Q53QN2; Q53T03; Q59GM7; Q99666; Q9H0B2"	""	""	"0"	"0"	"62.0"	"59.0"	"84.7"	"71.2"	"80.3"	"76.5"	"83.5"	"97.1"	"209.2"	"369.6"	"569.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q32MZ4"	"Leucine-rich repeat flightless-interacting protein 1 OS=Homo sapiens OX=9606 GN=LRRFIP1 PE=1 SV=2"	"13"	"9"	"18"	"9"	"808"	"89.2"	"4.65"	"3194.51"	"36.62"	"7"	"9"	"other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09738"	"9208"	"ENSG00000124831"	"LRRFIP1"	"E9PGZ2; hsa:9208; O75766; O75799; Q32MZ4; Q32MZ5; Q53T49; Q6PKG2; Q9Y607"	"IL-18 signaling pathway; 2q37 copy number variation syndrome"	"Signaling by cytosolic FGFR1 fusion mutants; Signaling by FGFR1 in disease; LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production"	"5"	"0"	"522.2"	"461.2"	"586.1"	"536.7"	"549.6"	"545.4"	"610.8"	"718.6"	"2222.2"	"5070.6"	"7371.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P54819"	"Adenylate kinase 2, mitochondrial OS=Homo sapiens OX=9606 GN=AK2 PE=1 SV=2"	"45"	"8"	"17"	"8"	"239"	"26.5"	"7.81"	"3713.74"	"36.62"	"6"	"7"	"other metabolic processes"	"cytoskeleton;mitochondrion;other cell component"	"kinase activity;other molecular function"	"Pf00406, Pf05191"	"204"	"ENSG00000004455"	"AK2"	"A8K6L1; B4DHH7; B4DL64; hsa:204; P54819; Q16856; Q5EB54; Q5TIF7; Q8TCY2; Q8TCY3"	""	"Interconversion of nucleotide di- and triphosphates"	"1"	"0"	"240.2"	"234.9"	"322.2"	"284.7"	"271.0"	"272.8"	"358.7"	"426.1"	"895.3"	"3317.6"	"6962.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q04637"	"Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4"	"7"	"8"	"19"	"7"	"1599"	"175.4"	"5.33"	"3434.35"	"36.53"	"7"	"8"	"protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02020, Pf02847, Pf02854"	"1981"	"ENSG00000114867"	"EIF4G1"	"D3DNT2; D3DNT4; D3DNT5; E9PFM1; G5E9S1; hsa:1981; O43177; O95066; Q04637; Q5HYG0; Q6ZN21; Q8N102"	"Translation factors; VEGFA-VEGFR2 signaling; Acute viral myocarditis; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Pleural mesothelioma"	"AUF1 (hnRNP D0) binds and destabilizes mRNA; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Translation initiation complex formation; Ribosomal scanning and start codon recognition; Deadenylation of mRNA; ISG15 antiviral mechanism; mTORC1-mediated signalling"	"18"	"1"	"627.0"	"581.0"	"682.5"	"565.9"	"641.5"	"647.0"	"777.5"	"864.7"	"1458.8"	"3521.2"	"5317.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q08170"	"Serine/arginine-rich splicing factor 4 OS=Homo sapiens OX=9606 GN=SRSF4 PE=1 SV=2"	"20"	"9"	"22"	"5"	"494"	"56.6"	"11.52"	"3535.22"	"36.45"	"7"	"9"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076"	"6429"	"ENSG00000116350"	"SRSF4"	"hsa:6429; Q08170; Q5VXP1; Q9BUA4; Q9UEB5"	"mRNA processing"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA Splicing - Major Pathway; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"6"	"4"	"1705.5"	"1595.5"	"1948.5"	"1723.2"	"1803.0"	"1557.2"	"2101.9"	"2404.1"	"2707.5"	"3554.5"	"5986.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NRZ9"	"Lymphoid-specific helicase OS=Homo sapiens OX=9606 GN=HELLS PE=1 SV=1"	"10"	"7"	"15"	"7"	"838"	"97.0"	"7.93"	"2389.19"	"36.25"	"5"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00176, Pf00271"	"3070"	"ENSG00000119969"	"HELLS"	"B2RB41; hsa:3070; Q3LID1; Q6I7N7; Q76H76; Q76H77; Q76H78; Q76H79; Q76H80; Q76H81; Q7Z397; Q7Z5X2; Q8N6P4; Q9H4P5; Q9NRZ9"	"Apoptosis; Apoptosis-related network due to altered Notch3 in ovarian cancer"	""	"2"	"0"	"422.8"	"419.3"	"458.0"	"399.6"	"478.6"	"452.7"	"503.3"	"591.9"	"1060.9"	"1578.2"	"1836.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UNF0"	"Protein kinase C and casein kinase substrate in neurons protein 2 OS=Homo sapiens OX=9606 GN=PACSIN2 PE=1 SV=2"	"19"	"8"	"15"	"8"	"486"	"55.7"	"5.20"	"2747.28"	"36.24"	"5"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00018, Pf00611"	"11252"	"ENSG00000100266"	"PACSIN2"	"hsa:11252; O95921; Q96HV9; Q9H0D3; Q9NPN1; Q9UNF0; Q9Y4V2"	""	"Clathrin-mediated endocytosis"	"1"	"0"	"332.6"	"295.6"	"346.6"	"323.3"	"350.1"	"357.9"	"419.1"	"524.6"	"1414.4"	"5352.7"	"8708.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15293"	"Reticulocalbin-1 OS=Homo sapiens OX=9606 GN=RCN1 PE=1 SV=1"	"27"	"7"	"14"	"7"	"331"	"38.9"	"5.00"	"2912.75"	"36.16"	"5"	"7"	"developmental processes"	"ER/Golgi"	"other molecular function"	"Pf13202"	"5954"	"ENSG00000049449"	"RCN1"	"B7Z1M1; D3DR00; hsa:5954; Q15293"	"VEGFA-VEGFR2 signaling"	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation"	"3"	"0"	"1240.4"	"1151.4"	"1470.1"	"1169.3"	"1435.0"	"1539.1"	"1749.4"	"2005.0"	"2038.4"	"2158.5"	"2627.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92900"	"Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2"	"10"	"7"	"15"	"7"	"1129"	"124.3"	"6.61"	"3096.21"	"36.14"	"6"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09416, Pf13086, Pf13087, Pf18141"	"5976"	"ENSG00000005007"	"UPF1"	"hsa:5976; O00239; O43343; Q86Z25; Q92842; Q92900"	"Pathophysiological roles of DUX4 in FSHD1"	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"3"	"0"	"340.2"	"354.5"	"367.1"	"380.3"	"392.3"	"321.4"	"424.7"	"587.7"	"1066.8"	"2263.2"	"2930.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N3R9"	"MAGUK p55 subfamily member 5 OS=Homo sapiens OX=9606 GN=MPP5 PE=1 SV=3"	"18"	"8"	"18"	"8"	"675"	"77.2"	"6.14"	"4346.35"	"35.92"	"6"	"7"	"cell organization and biogenesis;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf00595, Pf00625, Pf02828, Pf07653, Pf09060"	"64398"	"ENSG00000072415"	"PALS1"	"A1L380; hsa:64398; Q7Z631; Q86T98; Q8N3R9; Q8N7I5; Q9H9Q0"	"Epithelial to mesenchymal transition in colorectal cancer; Complement system in neuronal development and plasticity"	"Tight junction interactions; SARS-CoV-2 targets PDZ proteins in cell-cell junction; SARS-CoV-1 targets PDZ proteins in cell-cell junction"	"5"	"0"	"663.5"	"558.7"	"718.7"	"590.8"	"650.3"	"698.9"	"797.5"	"924.9"	"2181.9"	"4488.2"	"6605.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P20042"	"Eukaryotic translation initiation factor 2 subunit 2 OS=Homo sapiens OX=9606 GN=EIF2S2 PE=1 SV=2"	"33"	"12"	"22"	"12"	"333"	"38.4"	"5.80"	"5291.27"	"35.85"	"11"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01873"	"8894"	"ENSG00000125977"	"EIF2S2"	"hsa:8894; P20042; Q9BVU0; Q9UJE4"	"Translation factors; Brain-derived neurotrophic factor (BDNF) signaling pathway; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell; Primary ovarian insufficiency"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; ABC-family proteins mediated transport; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK1 (HRI) to heme deficiency; PERK regulates gene expression; Recycling of eIF2:GDP; Response of EIF2AK4 (GCN2) to amino acid deficiency"	"14"	"0"	"1175.6"	"859.7"	"1269.0"	"1090.6"	"1223.0"	"1222.7"	"1489.5"	"2267.6"	"8140.0"	"4772.7"	"3482.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13112"	"Chromatin assembly factor 1 subunit B OS=Homo sapiens OX=9606 GN=CHAF1B PE=1 SV=1"	"19"	"9"	"16"	"9"	"559"	"61.5"	"7.50"	"2349.41"	"35.84"	"7"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf00400, Pf15512"	"8208"	"ENSG00000159259"	"CHAF1B"	"hsa:8208; Q13112; Q99548"	""	""	"0"	"0"	"515.7"	"467.0"	"562.8"	"482.3"	"545.0"	"577.0"	"655.1"	"791.9"	"2046.3"	"3544.4"	"3977.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95782"	"AP-2 complex subunit alpha-1 OS=Homo sapiens OX=9606 GN=AP2A1 PE=1 SV=3"	"12"	"10"	"23"	"7"	"977"	"107.5"	"7.03"	"4043.44"	"35.64"	"9"	"9"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01602, Pf02296, Pf02883"	"160"	"ENSG00000196961"	"AP2A1"	"hsa:160; O95782; Q96CI7; Q96PP6; Q96PP7; Q9H070"	"Synaptic vesicle pathway; VEGFA-VEGFR2 signaling; GABA receptor signaling; EGF/EGFR signaling pathway; Fragile X syndrome; mBDNF and proBDNF regulation of GABA neurotransmission"	"Potential therapeutics for SARS; Recycling pathway of L1; MHC class II antigen presentation; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; LDL clearance; Trafficking of GluR2-containing AMPA receptors; Nef Mediated CD4 Down-regulation; Retrograde neurotrophin signalling; Nef Mediated CD8 Down-regulation; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; VLDLR internalisation and degradation"	"20"	"3"	"557.8"	"480.7"	"617.3"	"542.2"	"669.8"	"818.2"	"1713.7"	"4242.8"	"5002.4"	"4727.0"	"4364.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P41091"	"Eukaryotic translation initiation factor 2 subunit 3 OS=Homo sapiens OX=9606 GN=EIF2S3 PE=1 SV=3"	"24"	"9"	"20"	"9"	"472"	"51.1"	"8.40"	"3627.26"	"35.64"	"7"	"9"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03144, Pf09173"	"1968"	"ENSG00000130741"	"EIF2S3"	"A0A024RBY4; A8K2Y2; B2R5N2; B5BTZ4; hsa:1968; P41091; Q53HK3"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; ABC-family proteins mediated transport; Response of EIF2AK1 (HRI) to heme deficiency; PERK regulates gene expression; Recycling of eIF2:GDP; Response of EIF2AK4 (GCN2) to amino acid deficiency"	"12"	"0"	"701.1"	"688.9"	"721.6"	"631.3"	"745.3"	"737.2"	"913.2"	"1613.9"	"6003.8"	"5079.2"	"4212.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96CW1"	"AP-2 complex subunit mu OS=Homo sapiens OX=9606 GN=AP2M1 PE=1 SV=2"	"26"	"9"	"18"	"9"	"435"	"49.6"	"9.54"	"4222.65"	"35.58"	"8"	"6"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00928, Pf01217"	"1173"	"ENSG00000161203"	"AP2M1"	"A6NE12; D3DNT1; hsa:1173; P20172; P53679; Q96CW1"	"Synaptic vesicle pathway; GABA receptor signaling; EGF/EGFR signaling pathway; Fragile X syndrome; GDNF signaling"	"Potential therapeutics for SARS; Recycling pathway of L1; EPH-ephrin mediated repulsion of cells; Cargo recognition for clathrin-mediated endocytosis; VLDLR internalisation and degradation; MHC class II antigen presentation; WNT5A-dependent internalization of FZD4; LDL clearance; Nef Mediated CD4 Down-regulation; Retrograde neurotrophin signalling; Nef Mediated CD8 Down-regulation; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; Nef mediated downregulation of CD28 cell surface expression; Formation of annular gap junctions"	"21"	"0"	"211.8"	"240.2"	"267.3"	"232.5"	"283.8"	"411.7"	"1000.1"	"2636.6"	"3183.4"	"2921.4"	"2372.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86VM9"	"Zinc finger CCCH domain-containing protein 18 OS=Homo sapiens OX=9606 GN=ZC3H18 PE=1 SV=2"	"15"	"13"	"22"	"13"	"953"	"106.3"	"8.32"	"3711.25"	"35.37"	"11"	"11"	"other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf18044"	"124245"	"ENSG00000158545"	"ZC3H18"	"hsa:124245; Q86VM9; Q96DG4; Q96MP7"	""	""	"0"	"0"	"1562.9"	"1452.3"	"1602.3"	"1383.3"	"1596.6"	"1659.2"	"1766.8"	"1973.8"	"2394.6"	"3451.9"	"5096.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31946"	"14-3-3 protein beta/alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3"	"37"	"7"	"21"	"4"	"246"	"28.1"	"4.83"	"4903.47"	"35.37"	"7"	"6"	"transport;signal transduction;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00244"	"7529"	"ENSG00000166913"	"YWHAB"	"A8K9K2; E1P616; hsa:7529; P31946"	"Cell cycle; IL-3 signaling pathway; Myometrial relaxation and contraction pathways; Hepatitis B infection; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by BRAF and RAF1 fusions; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Regulation of localization of FOXO transcription factors; mTORC1-mediated signalling; TP53 Regulates Metabolic Genes; Signaling by Hippo; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RAF activation; SHOC2 M1731 mutant abolishes MRAS complex function; Gain-of-function MRAS complexes activate RAF signaling; RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Rap1 signalling; Negative regulation of MAPK pathway; Frs2-mediated activation; ARMS-mediated activation; Activation of BAD and translocation to mitochondria ; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"	"33"	"2"	"728.6"	"614.0"	"695.3"	"641.0"	"693.7"	"748.8"	"889.1"	"1032.9"	"1477.3"	"2093.1"	"2929.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14444"	"Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2"	"13"	"9"	"17"	"9"	"709"	"78.3"	"5.25"	"2401.77"	"35.26"	"7"	"9"	"cell organization and biogenesis;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf12287, Pf18293"	"4076"	"ENSG00000135387"	"CAPRIN1"	"A6NMY7; D3DR06; hsa:4076; Q14444; Q15074; Q6IMN4; Q6IMN7; Q9BV09"	""	""	"0"	"0"	"366.4"	"346.1"	"365.2"	"321.3"	"388.0"	"398.5"	"490.2"	"599.4"	"1397.6"	"3763.6"	"6225.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92747"	"Actin-related protein 2/3 complex subunit 1A OS=Homo sapiens OX=9606 GN=ARPC1A PE=2 SV=2"	"27"	"8"	"17"	"7"	"370"	"41.5"	"8.18"	"2676.45"	"35.14"	"6"	"8"	"cell organization and biogenesis"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf00400"	"10552"	"ENSG00000241685"	"ARPC1A"	"A4D276; B4DLQ7; D6W5S1; hsa:10552; Q7Z5U8; Q86WU5; Q8IXQ0; Q92747"	"Pathogenic Escherichia coli infection"	"Clathrin-mediated endocytosis; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; EPHB-mediated forward signaling"	"6"	"0"	"321.7"	"306.6"	"365.3"	"336.5"	"376.8"	"321.2"	"455.0"	"762.7"	"3599.2"	"6457.4"	"7843.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P1J9"	"Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1"	"23"	"12"	"22"	"12"	"531"	"60.5"	"9.61"	"4004.61"	"35.13"	"11"	"11"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf05179, Pf16050"	"79577"	"ENSG00000134371"	"CDC73"	"A6NLZ8; B2RBR2; hsa:79577; Q6P1J9; Q6PK51; Q96A07; Q9H245; Q9H5L7"	"Endoderm differentiation"	"Hedgehog 'on' state; Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events; Formation of the beta-catenin:TCF transactivating complex; E3 ubiquitin ligases ubiquitinate target proteins"	"7"	"0"	"1567.4"	"1469.0"	"1559.2"	"1368.0"	"1567.6"	"1605.1"	"1919.3"	"2201.7"	"3228.8"	"4981.4"	"6456.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35240"	"Merlin OS=Homo sapiens OX=9606 GN=NF2 PE=1 SV=1"	"20"	"13"	"24"	"13"	"595"	"69.6"	"6.47"	"5217.60"	"35.11"	"13"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity"	"Pf00373, Pf00769, Pf09379, Pf09380, Pf20492"	"4771"	"ENSG00000186575"	"NF2"	"hsa:4771; O95683; P35240; Q8WUJ2; Q969N0; Q969Q3; Q96T30; Q96T31; Q96T32; Q96T33; Q9BTW3; Q9UNG9; Q9UNH3; Q9UNH4"	"Ectoderm differentiation; Ectoderm differentiation; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-YAP signaling; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; 3q29 copy number variation syndrome; Pleural mesothelioma"	"Regulation of actin dynamics for phagocytic cup formation; RHO GTPases activate PAKs"	"10"	"0"	"1297.2"	"1072.2"	"1275.5"	"1099.3"	"1240.8"	"1279.6"	"1486.8"	"1944.8"	"7770.9"	"7976.2"	"7088.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q07666"	"KH domain-containing, RNA-binding, signal transduction-associated protein 1 OS=Homo sapiens OX=9606 GN=KHDRBS1 PE=1 SV=1"	"19"	"7"	"17"	"7"	"443"	"48.2"	"8.66"	"3124.89"	"35.07"	"6"	"7"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf16274, Pf16568"	"10657"	"ENSG00000121774"	"KHDRBS1"	"D3DPP3; hsa:10657; Q07666; Q6PJX7; Q8NB97; Q99760"	"Leptin signaling pathway; Primary ovarian insufficiency"	"PTK6 Regulates Proteins Involved in RNA Processing"	"3"	"0"	"1491.1"	"1529.8"	"1361.7"	"1231.1"	"1249.0"	"1375.8"	"1747.1"	"2168.3"	"2601.1"	"3214.2"	"4213.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08708"	"40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2"	"56"	"6"	"10"	"6"	"135"	"15.5"	"9.85"	"1143.87"	"35.05"	"3"	"6"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00833"	"6218"	"ENSG00000182774; ENSG00000278229"	"RPS17"	"B2R4U4; hsa:6218; P08708; P0CW22"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"489.2"	"526.2"	"515.0"	"442.9"	"542.4"	"516.9"	"667.1"	"778.2"	"972.9"	"1741.6"	"2066.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BZZ5"	"Apoptosis inhibitor 5 OS=Homo sapiens OX=9606 GN=API5 PE=1 SV=3"	"30"	"13"	"22"	"13"	"524"	"59.0"	"7.34"	"4230.70"	"35.03"	"11"	"10"	"other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf05918"	"8539"	"ENSG00000166181"	"API5"	"B4DGR0; B4DRJ2; B4E283; D3DR21; G3V1C3; hsa:8539; O15441; Q9BZZ5; Q9Y4J7"	""	""	"0"	"0"	"833.6"	"808.7"	"846.7"	"710.3"	"925.3"	"865.0"	"1067.3"	"1278.8"	"2294.4"	"5081.7"	"7676.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96I25"	"Splicing factor 45 OS=Homo sapiens OX=9606 GN=RBM17 PE=1 SV=1"	"25"	"9"	"17"	"8"	"401"	"44.9"	"5.97"	"2897.93"	"34.90"	"6"	"9"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf01585"	"84991"	"ENSG00000134453"	"RBM17"	"hsa:84991; Q96GY6; Q96I25"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"1"	"500.5"	"401.1"	"541.6"	"538.8"	"557.8"	"540.6"	"630.6"	"737.8"	"1132.5"	"3333.2"	"7038.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60306"	"RNA helicase aquarius OS=Homo sapiens OX=9606 GN=AQR PE=1 SV=4"	"5"	"8"	"19"	"8"	"1485"	"171.2"	"6.37"	"3907.01"	"34.85"	"8"	"7"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf13086, Pf13087, Pf16399"	"9716"	"ENSG00000021776"	"AQR"	"A0JP17; A5YKK3; hsa:9716; O60306; Q2YDX9; Q6IRU8; Q6PIC8"	""	"mRNA Splicing - Major Pathway; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	"5"	"0"	"321.4"	"272.2"	"360.8"	"308.6"	"347.8"	"369.7"	"405.8"	"527.5"	"945.1"	"2338.5"	"4640.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5SRE5"	"Nucleoporin NUP188 homolog OS=Homo sapiens OX=9606 GN=NUP188 PE=1 SV=1"	"7"	"9"	"19"	"9"	"1749"	"195.9"	"6.73"	"4266.72"	"34.84"	"8"	"8"	"transport"	"cytosol;nucleus"	"other molecular function"	"Pf10487"	"23511"	"ENSG00000095319"	"NUP188"	"hsa:23511; Q14675; Q2TA87; Q5SRE5; Q7Z3K8; Q8IWF1"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; Vpr-mediated nuclear import of PICs; Regulation of HSF1-mediated heat shock response; SUMOylation of chromatin organization proteins; SUMOylation of DNA damage response and repair proteins; HCMV Early Events; HCMV Late Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; snRNP Assembly; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; SUMOylation of SUMOylation proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Postmitotic nuclear pore complex (NPC) reformation"	"29"	"0"	"405.8"	"377.6"	"414.5"	"382.2"	"452.7"	"388.7"	"490.1"	"617.9"	"1071.5"	"2023.8"	"2839.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P84103"	"Serine/arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1"	"46"	"8"	"13"	"8"	"164"	"19.3"	"11.65"	"1557.13"	"34.82"	"4"	"7"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6428"	"ENSG00000112081"	"SRSF3"	"B4E241; hsa:6428; O08831; P23152; P84103; Q5R3K0"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript"	"6"	"0"	"1335.1"	"1262.1"	"1167.4"	"999.2"	"1051.0"	"976.7"	"1370.9"	"1789.5"	"2062.9"	"3133.0"	"5059.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14625"	"Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1"	"16"	"10"	"15"	"10"	"803"	"92.4"	"4.84"	"2128.87"	"34.73"	"6"	"9"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00183, Pf02518"	"7184"	"ENSG00000166598"	"HSP90B1"	"hsa:7184; P14625; Q96A97"	"Photodynamic therapy-induced unfolded protein response; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Prion disease pathway; PI3K-Akt signaling pathway; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Trafficking and processing of endosomal TLR; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Interleukin-4 and Interleukin-13 signaling; Scavenging by Class A Receptors; ATF6 (ATF6-alpha) activates chaperone genes"	"11"	"0"	"489.0"	"429.3"	"585.8"	"502.2"	"589.7"	"565.4"	"592.9"	"756.1"	"1250.2"	"2289.9"	"4158.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N684"	"Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1"	"19"	"8"	"20"	"8"	"471"	"52.0"	"8.00"	"3884.46"	"34.70"	"8"	"8"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"79869"	"ENSG00000149532"	"CPSF7"	"B3KU04; C9K0Q4; hsa:79869; Q7Z3H9; Q8N684; Q9H025; Q9H9V1"	""	"RHOBTB1 GTPase cycle; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"5"	"0"	"867.9"	"866.1"	"874.9"	"757.2"	"823.4"	"832.4"	"1030.7"	"1359.0"	"2683.7"	"4682.6"	"6964.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13620"	"Cullin-4B OS=Homo sapiens OX=9606 GN=CUL4B PE=1 SV=4"	"12"	"10"	"19"	"6"	"913"	"103.9"	"7.37"	"2765.03"	"34.62"	"7"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00888, Pf10557"	"8450"	"ENSG00000158290"	"CUL4B"	"B1APK5; B3KVX4; B7Z5K8; hsa:8450; Q13620; Q6PIE4; Q6UP07; Q7Z673; Q9BY37; Q9UEB7; Q9UED7"	"Mesodermal commitment pathway; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"Neddylation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; DNA Damage Recognition in GG-NER; Dual Incision in GG-NER"	"13"	"3"	"177.5"	"151.6"	"216.5"	"185.9"	"218.7"	"211.0"	"252.8"	"324.9"	"1128.0"	"3078.5"	"4941.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P18583"	"Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4"	"5"	"10"	"21"	"10"	"2426"	"263.7"	"5.64"	"4190.78"	"34.60"	"10"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf01585, Pf14709, Pf17069"	"6651"	"ENSG00000159140"	"SON"	"D3DSF5; D3DSF6; E7ETE8; E7EU67; E7EVW3; E9PFQ2; hsa:6651; O14487; O95981; P18583; Q14120; Q6PKE0; Q9H7B1; Q9P070; Q9P072; Q9UKP9; Q9UPY0"	""	""	"0"	"0"	"1029.7"	"913.8"	"1095.8"	"948.0"	"1037.6"	"1009.8"	"1204.1"	"1332.0"	"2013.5"	"4315.8"	"7314.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35232"	"Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1"	"38"	"10"	"18"	"10"	"272"	"29.8"	"5.76"	"3824.28"	"34.56"	"7"	"9"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01145"	"5245"	"ENSG00000167085"	"PHB1"	"B4DY47; hsa:5245; P35232; Q4VBQ0"	""	"RAF activation; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Processing of SMDT1"	"5"	"0"	"695.5"	"686.8"	"645.9"	"575.8"	"666.2"	"700.8"	"839.0"	"1020.7"	"1668.8"	"3118.2"	"4199.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14654"	"Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1"	"9"	"11"	"18"	"11"	"1257"	"133.7"	"8.44"	"2672.82"	"34.53"	"8"	"10"	"signal transduction"	"plasma membrane;other membranes;cytosol"	"signal transduction activity or receptor binding;other molecular function"	"Pf02174"	"8471"	"ENSG00000133124"	"IRS4"	"hsa:8471; O14654"	"Alzheimer's disease and miRNA effects; Adipogenesis; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Leptin-insulin signaling overlap; Insulin signaling; Alzheimer's disease"	"IRS-related events triggered by IGF1R"	"8"	"0"	"1032.9"	"901.9"	"1009.4"	"893.5"	"936.0"	"983.6"	"1160.6"	"1327.1"	"2630.7"	"4677.7"	"6242.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62701"	"40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2"	"39"	"12"	"23"	"12"	"263"	"29.6"	"10.15"	"3578.26"	"34.49"	"11"	"11"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00467, Pf00900, Pf01479, Pf08071, Pf16121"	"6191"	"ENSG00000198034"	"RPS4X"	"hsa:6191; P12631; P12750; P27576; P55831; P62701; Q14727; Q6IPY4"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"1400.4"	"1303.9"	"1295.4"	"1134.1"	"1293.9"	"1266.9"	"1611.2"	"2063.5"	"3009.3"	"5960.8"	"9358.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P53582"	"Methionine aminopeptidase 1 OS=Homo sapiens OX=9606 GN=METAP1 PE=1 SV=2"	"26"	"8"	"12"	"8"	"386"	"43.2"	"7.17"	"1723.93"	"34.45"	"4"	"8"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00557, Pf15801"	"23173"	"ENSG00000164024"	"METAP1"	"B4E2E6; hsa:23173; P53582"	""	"Inactivation, recovery and regulation of the phototransduction cascade"	"1"	"0"	"342.3"	"311.2"	"379.2"	"310.8"	"357.7"	"282.1"	"532.2"	"1004.4"	"1625.1"	"2928.6"	"3535.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9C0J8"	"pre-mRNA 3' end processing protein WDR33 OS=Homo sapiens OX=9606 GN=WDR33 PE=1 SV=2"	"9"	"7"	"12"	"7"	"1336"	"145.8"	"9.17"	"2590.94"	"34.43"	"5"	"7"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	""	"Pf00400"	"55339"	"ENSG00000136709"	"WDR33"	"hsa:55339; Q05DP8; Q53FG9; Q587J1; Q69YF7; Q6NUQ0; Q9C0J8; Q9NUL1"	""	"Transport of Mature mRNA Derived from an Intronless Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"5"	"0"	"467.0"	"419.0"	"515.3"	"462.2"	"547.0"	"490.5"	"573.2"	"683.8"	"888.5"	"1458.5"	"2262.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WUA2"	"Peptidyl-prolyl cis-trans isomerase-like 4 OS=Homo sapiens OX=9606 GN=PPIL4 PE=1 SV=1"	"26"	"10"	"16"	"10"	"492"	"57.2"	"5.92"	"2271.74"	"34.42"	"6"	"10"	"protein metabolism;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf00076, Pf00160"	"85313"	"ENSG00000131013"	"PPIL4"	"B2RD34; hsa:85313; Q7Z3Q5; Q8WUA2"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"193.7"	"204.8"	"210.9"	"192.9"	"232.1"	"223.6"	"269.2"	"385.6"	"1551.3"	"3345.7"	"4644.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11277"	"Spectrin beta chain, erythrocytic OS=Homo sapiens OX=9606 GN=SPTB PE=1 SV=5"	"3"	"7"	"21"	"1"	"2137"	"246.3"	"5.27"	"3741.73"	"34.31"	"7"	"6"	"cell organization and biogenesis"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf00307, Pf00435"	"6710"	"ENSG00000070182"	"SPTB"	"hsa:6710; P11277; Q15510; Q15519"	""	"COPI-mediated anterograde transport; RAF/MAP kinase cascade; NCAM signaling for neurite out-growth; Interaction between L1 and Ankyrins"	"4"	"0"	"16.9"	"15.6"	"24.6"	"32.7"	"32.0"	"31.3"	"23.8"	"31.4"	"83.3"	"178.9"	"261.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07197"	"Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3"	"12"	"11"	"22"	"10"	"916"	"102.4"	"4.91"	"4316.92"	"34.23"	"11"	"10"	"cell organization and biogenesis"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf00038, Pf04732"	"4741"	"ENSG00000104722"	"NEFM"	"B4DGN2; E9PBF7; hsa:4741; P07197; Q4QRK6"	"Amyotrophic lateral sclerosis (ALS); Physico-chemical features and toxicity-associated pathways; Ciliary landscape"	""	"3"	"0"	"1217.2"	"1131.8"	"1195.2"	"996.8"	"1174.9"	"1228.5"	"1376.6"	"1644.3"	"2190.8"	"2847.1"	"3668.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14978"	"Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2"	"15"	"10"	"20"	"10"	"699"	"73.6"	"9.47"	"3206.94"	"34.19"	"8"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05022"	"9221"	"ENSG00000166197"	"NOLC1"	"hsa:9221; Q14978; Q15030; Q5VV70; Q9BUV3"	""	""	"0"	"0"	"1072.2"	"826.9"	"1093.0"	"943.4"	"1033.1"	"1141.0"	"1269.2"	"1440.7"	"2194.6"	"2831.8"	"4147.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P42765"	"3-ketoacyl-CoA thiolase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAA2 PE=1 SV=2"	"25"	"6"	"11"	"6"	"397"	"41.9"	"8.09"	"1453.43"	"34.17"	"3"	"6"	"cell organization and biogenesis;other metabolic processes;stress response;transport"	"mitochondrion"	"other molecular function"	"Pf00108, Pf02803"	"10449"	"ENSG00000167315"	"ACAA2"	"hsa:10449; P42765; Q9BUT6"	"Fatty acid biosynthesis"	"Mitochondrial Fatty Acid Beta-Oxidation"	"2"	"0"	"183.9"	"179.4"	"216.2"	"179.5"	"213.9"	"205.3"	"223.4"	"313.0"	"882.5"	"1849.4"	"2895.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60264"	"SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1"	"9"	"10"	"20"	"4"	"1052"	"121.8"	"8.09"	"3719.53"	"34.10"	"10"	"10"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf09110, Pf09111"	"8467"	"ENSG00000153147"	"SMARCA5"	"hsa:8467; O60264"	"10q11.21q11.23 copy number variation syndrome"	"Deposition of new CENPA-containing nucleosomes at the centromere; B-WICH complex positively regulates rRNA expression; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; NoRC negatively regulates rRNA expression"	"5"	"0"	"337.7"	"336.9"	"365.6"	"321.8"	"381.5"	"386.1"	"467.2"	"548.4"	"955.8"	"1582.1"	"2112.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BW27"	"Nuclear pore complex protein Nup85 OS=Homo sapiens OX=9606 GN=NUP85 PE=1 SV=1"	"13"	"8"	"15"	"8"	"656"	"75.0"	"5.55"	"2638.47"	"34.00"	"6"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf07575"	"79902"	"ENSG00000125450"	"NUP85"	"B4DMQ3; B4DPW1; hsa:79902; Q8NDI4; Q9BW27; Q9H9U1"	""	"HCMV Late Events; HCMV Early Events; Transcriptional regulation by small RNAs; SARS-CoV-2 activates/modulates innate and adaptive immune responses; tRNA processing in the nucleus; Separation of Sister Chromatids; Viral Messenger RNA Synthesis; SUMOylation of DNA damage response and repair proteins; Rev-mediated nuclear export of HIV RNA; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Postmitotic nuclear pore complex (NPC) reformation"	"35"	"0"	"436.8"	"476.7"	"518.4"	"446.4"	"503.9"	"405.3"	"588.5"	"851.1"	"1373.9"	"2193.1"	"3050.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96T37"	"RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2"	"11"	"9"	"17"	"8"	"977"	"107.1"	"10.08"	"2859.02"	"33.95"	"8"	"8"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"other membranes;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf07744"	"64783"	"ENSG00000162775"	"RBM15"	"A1A693; hsa:64783; Q3ZB86; Q4V760; Q5D058; Q5T613; Q86VW9; Q96PE4; Q96SC5; Q96SC6; Q96SC9; Q96SD0; Q96T37; Q96T38; Q9BRA5; Q9H6R8; Q9H9Y0"	""	""	"0"	"1"	"765.7"	"650.9"	"723.1"	"650.7"	"754.9"	"813.6"	"1110.4"	"1640.5"	"2561.6"	"3321.2"	"3902.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q06124"	"Tyrosine-protein phosphatase non-receptor type 11 OS=Homo sapiens OX=9606 GN=PTPN11 PE=1 SV=3"	"26"	"11"	"18"	"11"	"593"	"68.0"	"7.30"	"3626.51"	"33.93"	"9"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00017, Pf00102"	"5781"	"ENSG00000179295"	"PTPN11"	"A8K1D9; hsa:5781; Q06124; Q96HD7"	"IL-5 signaling pathway; Heart development; IL-1 signaling pathway; Leptin signaling pathway; Prolactin signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; Pilocytic astrocytoma; Androgen receptor network in prostate cancer; B cell receptor signaling pathway; Interleukin-11 signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Alpha 6 beta 4 signaling pathway; IL-3 signaling pathway; Kit receptor signaling pathway; Hepatocyte growth factor receptor signaling; RAC1/PAK1/p38/MMP2 pathway; IL6 signaling pathway; Hepatitis C and hepatocellular carcinoma; VEGFA-VEGFR2 signaling; Embryonic stem cell pluripotency pathways; IL-4 signaling pathway; Ras signaling; EGF/EGFR signaling pathway; Fragile X syndrome; Cancer immunotherapy by CTLA4 blockade; Cancer immunotherapy by PD-1 blockade; Gastrin signaling pathway; Netrin-UNC5B signaling pathway; Insulin signaling; IL-2 signaling pathway; Angiotensin II receptor type 1 pathway; Kallmann syndrome; Orexin receptor pathway; GDNF signaling; Interferon type I signaling pathways; Type II interferon signaling; T-cell receptor signaling pathway"	"PIP3 activates AKT signaling; GPVI-mediated activation cascade; Constitutive Signaling by Aberrant PI3K in Cancer; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Platelet sensitization by LDL; CTLA4 inhibitory signaling; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Interleukin-3, Interleukin-5 and GM-CSF signaling; PD-1 signaling; Activation of IRF3, IRF7 mediated by TBK1, IKBKE; Signal regulatory protein family interactions; RET signaling; PI3K Cascade; Signaling by SCF-KIT; Downstream signal transduction; Tie2 Signaling; Interleukin-6 signaling; Signaling by Leptin; Regulation of IFNG signaling; Regulation of IFNA/IFNB signaling; Signaling by CSF3 (G-CSF); GAB1 signalosome; Signaling by CSF1 (M-CSF) in myeloid cells; PI-3K cascade:FGFR1; FRS-mediated FGFR1 signaling; PI-3K cascade:FGFR2; FRS-mediated FGFR2 signaling; FRS-mediated FGFR3 signaling; PI-3K cascade:FGFR3; FRS-mediated FGFR4 signaling; PI-3K cascade:FGFR4; Activated NTRK2 signals through FRS2 and FRS3; Spry regulation of FGF signaling; MAPK3 (ERK1) activation; MAPK1 (ERK2) activation; Prolactin receptor signaling; Interleukin-20 family signaling; Netrin mediated repulsion signals; Interleukin-37 signaling; PECAM1 interactions; MET activates PTPN11; STAT5 activation downstream of FLT3 ITD mutants; Regulation of RUNX1 Expression and Activity; STAT5 Activation"	"90"	"0"	"238.1"	"244.7"	"257.6"	"217.7"	"286.3"	"253.9"	"333.7"	"489.8"	"1850.0"	"2705.9"	"3345.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14966"	"Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2"	"7"	"12"	"21"	"12"	"1978"	"220.5"	"6.38"	"4858.56"	"33.85"	"11"	"10"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf12171"	"27332"	"ENSG00000075292"	"ZNF638"	"A0A096LPH6; B5MDV1; B7ZLD1; hsa:27332; Q14966; Q53R34; Q5XJ05; Q68DP3; Q6P2H2; Q7Z3T7; Q8NF92; Q8TCA1; Q9H2G1; Q9NP37"	""	"Transcriptional regulation of white adipocyte differentiation"	"1"	"0"	"1414.8"	"1182.9"	"1357.9"	"1217.3"	"1358.1"	"1388.4"	"1674.5"	"1831.9"	"3160.3"	"5014.2"	"6230.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NBS9"	"Thioredoxin domain-containing protein 5 OS=Homo sapiens OX=9606 GN=TXNDC5 PE=1 SV=2"	"21"	"8"	"16"	"8"	"432"	"47.6"	"5.97"	"2190.46"	"33.49"	"6"	"7"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;ER/Golgi;other cytoplasmic organelle"	"other molecular function"	"Pf00085"	"81567"	"ENSG00000239264"	"TXNDC5"	"B2RDM2; hsa:81567; Q5TCQ0; Q8NBS9; Q8ND33; Q8TCT2; Q9BVH9"	"VEGFA-VEGFR2 signaling"	"Neutrophil degranulation; Lysosome Vesicle Biogenesis; Golgi Associated Vesicle Biogenesis"	"4"	"0"	"932.6"	"985.2"	"862.3"	"803.7"	"991.0"	"968.8"	"1143.3"	"1572.3"	"1741.3"	"2356.4"	"2946.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P33991"	"DNA replication licensing factor MCM4 OS=Homo sapiens OX=9606 GN=MCM4 PE=1 SV=5"	"11"	"9"	"15"	"9"	"863"	"96.5"	"6.74"	"2184.16"	"33.44"	"6"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf14551, Pf17207, Pf17855"	"4173"	"ENSG00000104738"	"MCM4"	"hsa:4173; P33991; Q8NEH1; Q99658"	"Cell cycle; Gastric cancer network 1; Retinoblastoma gene in cancer; Ciliary landscape; G1 to S cell cycle control; DNA replication"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"12"	"0"	"480.5"	"525.6"	"568.0"	"476.7"	"475.3"	"494.4"	"622.1"	"833.6"	"1357.7"	"3273.1"	"7584.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15424"	"Scaffold attachment factor B1 OS=Homo sapiens OX=9606 GN=SAFB PE=1 SV=4"	"11"	"10"	"22"	"6"	"915"	"102.6"	"5.47"	"3911.12"	"33.43"	"9"	"9"	"cell organization and biogenesis;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf02037"	"6294"	"ENSG00000160633"	"SAFB"	"A0AV56; B7Z5B6; B7ZLP6; F5H0H3; hsa:6294; O60406; Q15424; Q59HH8"	"Interleukin-1 (IL-1) structural pathway"	"SUMOylation of transcription cofactors"	"2"	"4"	"1957.6"	"1865.6"	"2089.6"	"1805.0"	"1867.7"	"1798.7"	"2217.9"	"2470.0"	"2851.8"	"4781.2"	"10597.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08621"	"U1 small nuclear ribonucleoprotein 70 kDa OS=Homo sapiens OX=9606 GN=SNRNP70 PE=1 SV=2"	"30"	"10"	"19"	"10"	"437"	"51.5"	"9.94"	"3777.56"	"33.35"	"8"	"10"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf12220"	"6625"	"ENSG00000104852"	"SNRNP70"	"B3KUA3; hsa:6625; P08621; P78493; P78494; Q15364; Q15686; Q15687; Q15689; Q99377; Q9UE45; Q9UE46; Q9UE47; Q9UE48; Q9UFQ6"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"1074.6"	"999.1"	"1067.8"	"906.4"	"1045.9"	"1076.4"	"1182.9"	"1544.6"	"1930.1"	"2262.6"	"3455.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q07021"	"Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1"	"35"	"6"	"12"	"6"	"282"	"31.3"	"4.84"	"2299.34"	"33.33"	"4"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;translation activity;nucleic acid binding activity;other molecular function"	"Pf02330"	"708"	"ENSG00000108561"	"C1QBP"	"hsa:708; Q07021; Q2HXR8; Q9NNY8"	"Complement system; Mesodermal commitment pathway; Ebola virus infection in host"	"RHOC GTPase cycle; RHOA GTPase cycle; Intrinsic Pathway of Fibrin Clot Formation; Apoptotic factor-mediated response; Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function"	"8"	"0"	"477.5"	"368.3"	"479.9"	"443.7"	"483.8"	"500.6"	"531.8"	"606.9"	"808.5"	"1172.3"	"1699.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23396"	"40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2"	"54"	"11"	"22"	"11"	"243"	"26.7"	"9.66"	"3735.09"	"33.31"	"10"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;translational apparatus;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00189, Pf07650"	"6188"	"ENSG00000149273"	"RPS3"	"B2R7N5; hsa:6188; J3KN86; P23396; Q498B5; Q8NI95"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"563.7"	"576.8"	"608.6"	"524.2"	"571.6"	"600.6"	"700.9"	"892.2"	"1523.1"	"3175.7"	"4663.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60709"	"Actin, cytoplasmic 1 OS=Homo sapiens OX=9606 GN=ACTB PE=1 SV=1"	"25"	"8"	"15"	"2"	"375"	"41.7"	"5.48"	"3158.04"	"33.17"	"6"	"7"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00022"	"60"	"ENSG00000075624"	"ACTB"	"hsa:60; P02570; P60709; P70514; P99021; Q11211; Q64316; Q75MN2; Q96B34; Q96HG5"	"Arrhythmogenic right ventricular cardiomyopathy; Pathogenic Escherichia coli infection; Common pathways underlying drug addiction; Myometrial relaxation and contraction pathways; Focal adhesion; Fas ligand pathway and stress induction of heat shock proteins; Ebola virus infection in host; Acute viral myocarditis; Thermogenesis; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Overlap between signal transduction pathways contributing to LMNA laminopathies; Pleural mesothelioma; Regulation of actin cytoskeleton; Network map of SARS-CoV-2 signaling pathway"	"RHO GTPases Activate Formins; UCH proteinases; RHO GTPases activate IQGAPs; Translocation of SLC2A4 (GLUT4) to the plasma membrane; VEGFA-VEGFR2 Pathway; B-WICH complex positively regulates rRNA expression; HATs acetylate histones; Signaling by BRAF and RAF1 fusions; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; Recycling pathway of L1; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; RHO GTPases Activate WASPs and WAVEs; RHOF GTPase cycle; Clathrin-mediated endocytosis; EPHB-mediated forward signaling; Factors involved in megakaryocyte development and platelet production; EPH-ephrin mediated repulsion of cells; Interaction between L1 and Ankyrins; Prefoldin mediated transfer of substrate  to CCT/TriC; Adherens junctions interactions; DNA Damage Recognition in GG-NER; Formation of annular gap junctions; Folding of actin by CCT/TriC; Cell-extracellular matrix interactions"	"47"	"7"	"1125.5"	"1243.8"	"1249.6"	"1239.8"	"1048.6"	"891.0"	"1248.1"	"1638.8"	"3065.5"	"4424.6"	"6314.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5BKZ1"	"DBIRD complex subunit ZNF326 OS=Homo sapiens OX=9606 GN=ZNF326 PE=1 SV=2"	"15"	"7"	"19"	"7"	"582"	"65.6"	"5.15"	"3970.62"	"33.12"	"7"	"6"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04988"	"284695"	"ENSG00000162664"	"ZNF326"	"A8MYX1; B4DLN0; B4E179; hsa:284695; Q5BKZ1; Q5VW93; Q5VW94; Q5VW96; Q5VW97; Q6NSA2; Q7Z638; Q7Z6C2"	""	""	"0"	"0"	"1152.8"	"1039.5"	"1143.1"	"1033.4"	"1164.0"	"1149.8"	"1410.7"	"1684.1"	"1971.8"	"2621.1"	"3870.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P34932"	"Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4"	"18"	"13"	"22"	"9"	"840"	"94.3"	"5.19"	"4381.43"	"33.12"	"11"	"10"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport"	"non-structural extracellular;cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf00012"	"3308"	"ENSG00000170606"	"HSPA4"	"hsa:3308; O95756; P34932; Q2TAL4; Q9BUK9"	"Parkin-ubiquitin proteasomal system pathway"	"Regulation of HSF1-mediated heat shock response"	"2"	"3"	"1125.3"	"957.0"	"1309.2"	"1167.1"	"1188.7"	"1310.9"	"1446.3"	"1725.1"	"2284.4"	"3521.5"	"5474.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62857"	"40S ribosomal protein S28 OS=Homo sapiens OX=9606 GN=RPS28 PE=1 SV=1"	"72"	"7"	"18"	"7"	"69"	"7.8"	"10.70"	"3933.92"	"33.12"	"7"	"7"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01200"	"6234"	"ENSG00000233927"	"RPS28"	"hsa:6234; P25112; P62857"	"Cytoplasmic ribosomal proteins"	"Major pathway of rRNA processing in the nucleolus and cytosol; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"914.5"	"648.9"	"915.6"	"854.8"	"734.6"	"733.8"	"967.6"	"1060.6"	"1395.6"	"2202.7"	"3322.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P26038"	"Moesin OS=Homo sapiens OX=9606 GN=MSN PE=1 SV=3"	"25"	"14"	"27"	"6"	"577"	"67.8"	"6.40"	"6915.37"	"33.09"	"14"	"9"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00373, Pf00769, Pf09379, Pf09380, Pf20492"	"4478"	"ENSG00000147065"	"MSN"	"hsa:4478; P26038"	"Glial cell differentiation; AGE/RAGE pathway; Measles virus infection; 16p11.2 proximal deletion syndrome; Regulation of actin cytoskeleton"	"Recycling pathway of L1; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Signaling by ALK fusions and activated point mutants"	"10"	"2"	"685.5"	"630.7"	"746.1"	"587.3"	"670.6"	"770.5"	"922.2"	"1110.0"	"2926.2"	"3779.3"	"3412.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q2NL82"	"Pre-rRNA-processing protein TSR1 homolog OS=Homo sapiens OX=9606 GN=TSR1 PE=1 SV=1"	"15"	"10"	"19"	"10"	"804"	"91.8"	"7.42"	"3019.23"	"33.05"	"8"	"9"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04950, Pf08142"	"55720"	"ENSG00000167721"	"TSR1"	"hsa:55720; Q2NL82; Q8WUY5; Q9NVT0; Q9P2E6"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"341.0"	"310.4"	"353.7"	"324.5"	"380.6"	"419.6"	"551.1"	"818.2"	"1979.6"	"3688.4"	"3787.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94826"	"Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1"	"17"	"9"	"18"	"9"	"608"	"67.4"	"7.12"	"3589.93"	"32.99"	"9"	"9"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00515, Pf13181"	"9868"	"ENSG00000154174"	"TOMM70"	"D3DN48; hsa:9868; O94826"	"Mitochondrial immune response to SARS-CoV-2; SARS-CoV-2 B.1.1.7 variant antagonises innate immune activation; SARS-CoV-2 mitochondrial chronic oxidative stress and endothelial dysfunction"	"Ub-specific processing proteases; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Mitochondrial protein import; DDX58/IFIH1-mediated induction of interferon-alpha/beta; SARS-CoV-1 activates/modulates innate immune responses; PINK1-PRKN Mediated Mitophagy"	"9"	"0"	"349.7"	"323.2"	"403.5"	"352.3"	"408.7"	"362.4"	"451.5"	"613.9"	"2738.1"	"4404.9"	"5845.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P00367"	"Glutamate dehydrogenase 1, mitochondrial OS=Homo sapiens OX=9606 GN=GLUD1 PE=1 SV=2"	"24"	"10"	"18"	"10"	"558"	"61.4"	"7.80"	"2461.14"	"32.98"	"8"	"10"	"other metabolic processes;other biological processes"	"mitochondrion;ER/Golgi;other cell component"	"other molecular function"	"Pf00208, Pf02812"	"2746"	"ENSG00000148672"	"GLUD1"	"B3KV55; B4DGN5; hsa:2746; P00367; Q5TBU3"	"VEGFA-VEGFR2 signaling; Amino acid metabolism; Metabolic reprogramming in colon cancer; 22q11.2 copy number variation syndrome; Amino acid metabolism pathway excerpt: histidine catabolism extension; 10q22q23 copy number variation"	"Transcriptional activation of mitochondrial biogenesis; Glutamate and glutamine metabolism"	"8"	"0"	"420.3"	"398.3"	"429.6"	"390.1"	"416.2"	"421.0"	"501.6"	"602.5"	"1143.1"	"3437.8"	"7274.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92733"	"Proline-rich protein PRCC OS=Homo sapiens OX=9606 GN=PRCC PE=1 SV=1"	"15"	"6"	"12"	"5"	"491"	"52.4"	"5.10"	"1782.65"	"32.92"	"4"	"5"	"cell cycle OR cell proliferation;other biological processes"	"nucleus"	""	"Pf10253"	"5546"	"ENSG00000143294"	"PRCC"	"A8K1F7; hsa:5546; O00665; O00724; Q5SZ06; Q92733"	"Type 2 papillary renal cell carcinoma; IL-18 signaling pathway"	"mRNA Splicing - Major Pathway"	"3"	"1"	"1144.9"	"937.7"	"1169.5"	"1106.6"	"1189.7"	"1157.8"	"1255.1"	"1292.3"	"1708.5"	"2937.4"	"3646.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P33176"	"Kinesin-1 heavy chain OS=Homo sapiens OX=9606 GN=KIF5B PE=1 SV=1"	"10"	"6"	"13"	"5"	"963"	"109.6"	"6.51"	"2456.87"	"32.92"	"5"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225"	"3799"	"ENSG00000170759"	"KIF5B"	"A0AVB2; hsa:3799; P33176; Q5VZ85"	"Alzheimer's disease and miRNA effects; Envelope proteins and their potential roles in EDMD physiopathology; Insulin signaling; CCL18 signaling pathway; Alzheimer's disease"	"COPI-dependent Golgi-to-ER retrograde traffic; MHC class II antigen presentation; Kinesins; Insulin processing; Nuclear events stimulated by ALK signaling in cancer; RHO GTPases activate KTN1"	"12"	"1"	"229.8"	"205.2"	"268.4"	"217.3"	"252.9"	"253.6"	"268.7"	"376.0"	"1058.6"	"2798.0"	"3859.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6PI48"	"Aspartate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=DARS2 PE=1 SV=1"	"13"	"8"	"18"	"8"	"645"	"73.5"	"8.02"	"3494.96"	"32.88"	"8"	"7"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00152, Pf01336, Pf02938"	"55157"	"ENSG00000117593"	"DARS2"	"hsa:55157; Q6PI48"	""	"Mitochondrial tRNA aminoacylation"	"1"	"0"	"688.3"	"627.3"	"711.5"	"629.9"	"660.7"	"615.1"	"813.3"	"995.8"	"1732.0"	"3468.1"	"4771.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15056"	"Eukaryotic translation initiation factor 4H OS=Homo sapiens OX=9606 GN=EIF4H PE=1 SV=5"	"29"	"6"	"13"	"6"	"248"	"27.4"	"7.23"	"2036.45"	"32.73"	"3"	"6"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"7458"	"ENSG00000106682"	"EIF4H"	"A8K3R1; D3DXF6; D3DXF8; hsa:7458; Q15056"	"Translation factors; 7q11.23 copy number variation syndrome"	"L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Translation initiation complex formation; Ribosomal scanning and start codon recognition"	"7"	"0"	"235.0"	"194.6"	"222.2"	"215.3"	"246.6"	"217.5"	"267.7"	"325.6"	"1021.4"	"3342.9"	"4548.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14776"	"Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2"	"10"	"9"	"17"	"9"	"1098"	"123.8"	"8.65"	"3010.85"	"32.71"	"8"	"9"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00397, Pf01846"	"10915"	"ENSG00000113649"	"TCERG1"	"hsa:10915; O14776; Q2NKN2; Q59EA1"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"875.5"	"811.2"	"848.6"	"739.1"	"880.8"	"851.9"	"1009.9"	"1122.3"	"1700.9"	"3090.8"	"4162.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q05519"	"Serine/arginine-rich splicing factor 11 OS=Homo sapiens OX=9606 GN=SRSF11 PE=1 SV=1"	"18"	"8"	"14"	"8"	"484"	"53.5"	"10.52"	"2451.55"	"32.66"	"6"	"8"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00076"	"9295"	"ENSG00000116754"	"SRSF11"	"hsa:9295; Q05519; Q5T758; Q8IWE6"	""	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"5"	"0"	"270.2"	"324.9"	"262.2"	"226.9"	"275.9"	"242.2"	"302.3"	"364.1"	"1168.1"	"4339.9"	"7056.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P24752"	"Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1"	"24"	"7"	"12"	"7"	"427"	"45.2"	"8.85"	"1460.57"	"32.61"	"3"	"7"	"other metabolic processes;stress response;developmental processes;other biological processes"	"mitochondrion;ER/Golgi"	"other molecular function"	"Pf00108, Pf02803"	"38"	"ENSG00000075239"	"ACAT1"	"B2R6H1; G3XAB4; hsa:38; P24752; Q96FG8"	"Fatty acid beta-oxidation; Tryptophan metabolism; SARS-CoV-2 and COVID-19 pathway"	"Branched-chain amino acid catabolism; Utilization of Ketone Bodies; Synthesis of Ketone Bodies"	"6"	"0"	"329.7"	"336.3"	"371.0"	"298.4"	"369.1"	"377.3"	"402.7"	"488.5"	"1099.2"	"3304.9"	"5944.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52701"	"DNA mismatch repair protein Msh6 OS=Homo sapiens OX=9606 GN=MSH6 PE=1 SV=2"	"8"	"10"	"17"	"10"	"1360"	"152.7"	"6.90"	"2744.84"	"32.60"	"8"	"9"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00488, Pf00855, Pf01624, Pf05188, Pf05190, Pf05192"	"2956"	"ENSG00000116062"	"MSH6"	"B4DF41; B4E3I4; F5H2F9; hsa:2956; O43706; O43917; P52701; Q8TCX4; Q9BTB5"	"Glioblastoma signaling pathways; Retinoblastoma gene in cancer; Chromosomal and microsatellite instability in colorectal cancer ; DNA repair pathways, full network; DNA mismatch repair"	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Defective Mismatch Repair Associated With MSH2; Defective Mismatch Repair Associated With MSH6"	"8"	"0"	"572.1"	"524.6"	"590.9"	"499.8"	"581.3"	"535.4"	"650.0"	"912.9"	"1638.3"	"3740.6"	"5934.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q69YN2"	"CWF19-like protein 1 OS=Homo sapiens OX=9606 GN=CWF19L1 PE=1 SV=2"	"17"	"7"	"17"	"7"	"538"	"60.6"	"7.24"	"3975.06"	"32.57"	"7"	"6"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"enzyme regulator activity"	"Pf04676, Pf04677"	"55280"	"ENSG00000095485"	"CWF19L1"	"B4DHX1; D3DR66; hsa:55280; Q5W0I3; Q69YN2; Q96HC3; Q9H865; Q9NV13"	""	""	"0"	"0"	"262.4"	"251.2"	"297.6"	"265.1"	"315.4"	"302.1"	"353.8"	"502.0"	"1559.2"	"2447.8"	"3211.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60832"	"H/ACA ribonucleoprotein complex subunit DKC1 OS=Homo sapiens OX=9606 GN=DKC1 PE=1 SV=3"	"13"	"6"	"16"	"6"	"514"	"57.6"	"9.42"	"3435.29"	"32.43"	"6"	"6"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01472, Pf01509, Pf08068, Pf16198"	"1736"	"ENSG00000130826"	"DKC1"	"F5BSB3; hsa:1736; O43845; O60832; Q96G67; Q9Y505"	""	"rRNA modification in the nucleus and cytosol; Telomere Extension By Telomerase"	"2"	"0"	"568.2"	"532.0"	"577.0"	"493.1"	"530.5"	"571.9"	"630.6"	"752.9"	"1514.9"	"3026.1"	"3878.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P39019"	"40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2"	"45"	"8"	"19"	"8"	"145"	"16.1"	"10.32"	"3919.98"	"32.33"	"8"	"8"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01090"	"6223"	"ENSG00000105372"	"RPS19"	"hsa:6223; P39019"	"Complement system; Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"20"	"0"	"1234.5"	"1215.6"	"1307.1"	"1149.2"	"1294.2"	"1289.0"	"1543.4"	"1699.9"	"2030.0"	"2574.9"	"2859.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P78406"	"mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1"	"26"	"8"	"16"	"8"	"368"	"40.9"	"7.83"	"3391.18"	"32.28"	"7"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00400"	"8480"	"ENSG00000101146"	"RAE1"	"A8K882; hsa:8480; O15306; P78406; Q3SYL7; Q5TCH8; Q6V708; Q9H100; Q9NQM6"	"IL-18 signaling pathway; SARS-CoV-2 innate immunity evasion and cell-specific immune response"	"Transcriptional regulation by small RNAs; HCMV Early Events; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Regulation of HSF1-mediated heat shock response; HCMV Late Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; Nuclear Pore Complex (NPC) Disassembly; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"30"	"0"	"1118.1"	"856.2"	"1177.6"	"1066.7"	"1208.4"	"1188.3"	"1352.1"	"1654.1"	"2897.7"	"4844.2"	"7410.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P32119"	"Peroxiredoxin-2 OS=Homo sapiens OX=9606 GN=PRDX2 PE=1 SV=5"	"26"	"7"	"18"	"6"	"198"	"21.9"	"5.97"	"4316.62"	"32.24"	"6"	"6"	"cell cycle OR cell proliferation;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00578, Pf10417"	"7001"	"ENSG00000167815"	"PRDX2"	"A8K0C0; hsa:7001; P31945; P32118; P32119; P35701; Q6FHG4; Q92763; Q9UC23"	"Selenium micronutrient network; VEGFA-VEGFR2 signaling"	"TP53 Regulates Metabolic Genes; Detoxification of Reactive Oxygen Species; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"	"5"	"0"	"270.2"	"267.4"	"324.7"	"245.8"	"281.7"	"280.2"	"369.5"	"500.3"	"1634.1"	"4861.7"	"7532.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13769"	"THO complex subunit 5 homolog OS=Homo sapiens OX=9606 GN=THOC5 PE=1 SV=2"	"15"	"7"	"15"	"7"	"683"	"78.5"	"6.87"	"2470.30"	"32.13"	"6"	"7"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf09766"	"8563"	"ENSG00000100296"	"THOC5"	"hsa:8563; O60839; Q13769; Q9UPZ5"	""	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript; Signaling by CSF1 (M-CSF) in myeloid cells"	"4"	"0"	"339.6"	"316.6"	"387.3"	"333.5"	"381.2"	"351.8"	"465.2"	"601.7"	"931.4"	"1491.0"	"2210.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16576"	"Histone-binding protein RBBP7 OS=Homo sapiens OX=9606 GN=RBBP7 PE=1 SV=1"	"22"	"9"	"16"	"3"	"425"	"47.8"	"5.05"	"2660.17"	"32.10"	"7"	"9"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400, Pf12265"	"5931"	"ENSG00000102054"	"RBBP7"	"hsa:5931; Q16576; Q5JP00"	"Retinoblastoma gene in cancer; Interactome of polycomb repressive complex 2 (PRC2) ; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"HCMV Early Events; Deposition of new CENPA-containing nucleosomes at the centromere; Neddylation; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Potential therapeutics for SARS; Oxidative Stress Induced Senescence; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6; HDACs deacetylate histones; RMTs methylate histone arginines; PKMTs methylate histone lysines; HATs acetylate histones; RNA Polymerase I Transcription Initiation; PRC2 methylates histones and DNA; Defective pyroptosis; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of TP53 Activity through Acetylation"	"20"	"0"	"199.3"	"219.3"	"190.1"	"177.3"	"191.1"	"227.6"	"256.0"	"317.4"	"443.5"	"883.1"	"1304.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14839"	"Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2"	"6"	"10"	"18"	"10"	"1912"	"217.9"	"5.86"	"3425.22"	"32.08"	"9"	"9"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf00385, Pf00628, Pf06461, Pf06465, Pf08073, Pf08074"	"1108"	"ENSG00000111642"	"CHD4"	"hsa:1108; Q14839; Q8IXZ5"	"Rett syndrome causing genes; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"RNA Polymerase I Transcription Initiation; Potential therapeutics for SARS; Regulation of PTEN gene transcription; HDACs deacetylate histones; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of TP53 Activity through Acetylation; NGF-stimulated transcription"	"9"	"0"	"556.8"	"536.5"	"583.0"	"511.8"	"583.2"	"594.7"	"705.1"	"879.8"	"1786.6"	"4623.1"	"5237.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q00610"	"Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5"	"7"	"9"	"17"	"9"	"1675"	"191.5"	"5.69"	"3383.96"	"32.01"	"8"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00637, Pf01394, Pf09268, Pf13838"	"1213"	"ENSG00000141367"	"CLTC"	"D3DU00; hsa:1213; Q00610; Q6N0A0; Q86TF2"	"Synaptic vesicle pathway; VEGFA-VEGFR2 signaling; Ebola virus infection in host; Fragile X syndrome; 7q11.23 copy number variation syndrome; Complement and coagulation cascades"	"ALK mutants bind TKIs; Nuclear events stimulated by ALK signaling in cancer; Recycling pathway of L1; MHC class II antigen presentation; RHOV GTPase cycle; Lysosome Vesicle Biogenesis; RHOU GTPase cycle; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; LDL clearance; Retrograde neurotrophin signalling; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; VLDLR internalisation and degradation; Entry of Influenza Virion into Host Cell via Endocytosis; Formation of annular gap junctions"	"25"	"0"	"569.8"	"662.9"	"583.0"	"492.8"	"605.6"	"574.6"	"764.8"	"1093.8"	"1367.5"	"2080.1"	"2871.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15371"	"Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1"	"22"	"8"	"14"	"8"	"548"	"63.9"	"6.05"	"2548.64"	"31.93"	"6"	"8"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf05091"	"8664"	"ENSG00000100353"	"EIF3D"	"A8MWD3; B2R7D4; B4DTF8; B4DVY1; hsa:8664; O15371; Q3MJD9; Q5M9Q6"	"Translation factors; VEGFA-VEGFR2 signaling; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"9"	"0"	"347.9"	"316.6"	"396.6"	"372.0"	"395.1"	"380.5"	"435.5"	"543.5"	"863.2"	"1308.4"	"3446.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95232"	"Luc7-like protein 3 OS=Homo sapiens OX=9606 GN=LUC7L3 PE=1 SV=2"	"19"	"8"	"18"	"8"	"432"	"51.4"	"9.79"	"2779.08"	"31.87"	"6"	"8"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf03194"	"51747"	"ENSG00000108848"	"LUC7L3"	"B3KN54; D3DTY1; hsa:51747; O95232; Q6PHR9; Q9NUY0; Q9P2S7"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"1337.9"	"1016.9"	"1250.7"	"1115.8"	"1241.5"	"1200.7"	"1401.6"	"1580.9"	"3594.4"	"9746.2"	"16042.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NTK5"	"Obg-like ATPase 1 OS=Homo sapiens OX=9606 GN=OLA1 PE=1 SV=2"	"29"	"10"	"19"	"10"	"396"	"44.7"	"7.81"	"3566.61"	"31.77"	"10"	"9"	"other metabolic processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cell component"	"translation activity;other molecular function"	"Pf01926, Pf06071"	"29789"	"ENSG00000138430"	"OLA1"	"D7EHM2; hsa:29789; Q5BJD7; Q8NCI8; Q96CU1; Q96SV2; Q9NTK5; Q9P1D3; Q9UNY9; Q9Y6G4"	""	"Platelet degranulation"	"1"	"0"	"640.8"	"587.4"	"692.2"	"602.7"	"718.4"	"766.9"	"897.8"	"1138.6"	"2063.6"	"4457.9"	"7325.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q10567"	"AP-1 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP1B1 PE=1 SV=2"	"11"	"10"	"19"	"1"	"949"	"104.6"	"5.06"	"3933.92"	"31.67"	"9"	"8"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"13.4"	"8.0"	"13.4"	"17.4"	"17.3"	"17.7"	"28.0"	"62.3"	"119.0"	"212.7"	"374.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14566"	"DNA replication licensing factor MCM6 OS=Homo sapiens OX=9606 GN=MCM6 PE=1 SV=1"	"16"	"10"	"17"	"10"	"821"	"92.8"	"5.41"	"2725.67"	"31.66"	"8"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf14551, Pf17207, Pf17855, Pf18263"	"4175"	"ENSG00000076003"	"MCM6"	"B2R6H2; hsa:4175; Q13504; Q14566; Q99859"	"Cell cycle; Retinoblastoma gene in cancer; Ciliary landscape; G1 to S cell cycle control; DNA replication"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"11"	"0"	"371.6"	"340.9"	"438.0"	"366.3"	"399.7"	"373.5"	"491.9"	"608.7"	"988.3"	"2179.2"	"4778.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NUP9"	"Protein lin-7 homolog C OS=Homo sapiens OX=9606 GN=LIN7C PE=1 SV=1"	"28"	"8"	"19"	"4"	"197"	"21.8"	"8.43"	"3804.79"	"31.65"	"8"	"7"	"cell-cell signaling;transport;other biological processes"	"plasma membrane;other membranes;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00595, Pf02828"	"55327"	"ENSG00000148943"	"LIN7C"	"hsa:55327; Q9NUP9"	""	"Neurexins and neuroligins; Assembly and cell surface presentation of NMDA receptors; Dopamine Neurotransmitter Release Cycle"	"3"	"0"	"491.5"	"418.9"	"492.8"	"393.3"	"386.8"	"461.4"	"538.3"	"635.5"	"1536.9"	"2484.5"	"3197.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P34897"	"Serine hydroxymethyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=SHMT2 PE=1 SV=3"	"23"	"12"	"22"	"12"	"504"	"56.0"	"8.53"	"3998.65"	"31.61"	"11"	"10"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00464"	"6472"	"ENSG00000182199"	"SHMT2"	"B7Z9F1; E7EQ19; E7EU43; hsa:6472; O00740; P34897; Q8N1A5"	"Glycine metabolism; Vitamin B12 metabolism; Folate metabolism; One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Neuroinflammation and glutamatergic signaling; Metabolic Epileptic Disorders"	"RHOG GTPase cycle; Metabolism of folate and pterines"	"11"	"0"	"1292.7"	"1359.0"	"1118.1"	"1077.5"	"1236.2"	"1128.2"	"1456.9"	"1845.7"	"2612.9"	"4136.2"	"6368.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23193"	"Transcription elongation factor A protein 1 OS=Homo sapiens OX=9606 GN=TCEA1 PE=1 SV=2"	"35"	"11"	"23"	"11"	"301"	"33.9"	"8.38"	"5064.96"	"31.60"	"11"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01096, Pf07500, Pf08711"	"6917"	"ENSG00000187735"	"TCEA1"	"A6NF25; A8K339; hsa:6917; P23193; Q15563; Q6FG87"	""	"Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	"15"	"0"	"581.0"	"495.7"	"658.6"	"550.0"	"615.6"	"595.9"	"769.0"	"1319.0"	"3130.8"	"5383.9"	"8072.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16513"	"Serine/threonine-protein kinase N2 OS=Homo sapiens OX=9606 GN=PKN2 PE=1 SV=1"	"11"	"9"	"17"	"9"	"984"	"112.0"	"6.30"	"2699.00"	"31.57"	"8"	"9"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00433, Pf02185"	"5586"	"ENSG00000065243"	"PKN2"	"B4DQ21; B4DTP5; B4DVG1; D3DT24; hsa:5586; Q08AF4; Q16513; Q9H1W4"	"PI3K-Akt signaling pathway"	"RAC1 GTPase cycle; RHO GTPases activate PKNs; RHOC GTPase cycle; RHOA GTPase cycle; RHOB GTPase cycle"	"6"	"0"	"229.7"	"211.1"	"260.1"	"239.1"	"263.6"	"267.6"	"325.3"	"405.0"	"1149.2"	"1966.7"	"2434.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43795"	"Unconventional myosin-Ib OS=Homo sapiens OX=9606 GN=MYO1B PE=1 SV=3"	"8"	"8"	"16"	"7"	"1136"	"131.9"	"9.38"	"2458.27"	"31.47"	"6"	"8"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00063, Pf00612, Pf06017"	"4430"	"ENSG00000128641"	"MYO1B"	"hsa:4430; O43794; O43795; Q7Z6L5"	""	""	"0"	"0"	"375.8"	"388.6"	"405.8"	"370.7"	"413.7"	"440.3"	"528.0"	"710.0"	"1637.6"	"2743.4"	"3758.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P37802"	"Transgelin-2 OS=Homo sapiens OX=9606 GN=TAGLN2 PE=1 SV=3"	"49"	"7"	"12"	"7"	"199"	"22.4"	"8.25"	"2358.95"	"31.27"	"5"	"7"	"cell organization and biogenesis;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton"	"cytoskeletal activity"	"Pf00307, Pf00402"	"8407"	"ENSG00000158710"	"TAGLN2"	"E9KL39; hsa:8407; P37802; Q5JRQ6; Q5JRQ7; Q6FGI1; Q9BUH5; Q9H4P0"	""	"Platelet degranulation"	"1"	"0"	"164.0"	"161.2"	"202.4"	"195.3"	"215.2"	"169.8"	"227.1"	"302.1"	"486.6"	"1248.2"	"3486.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96AG4"	"Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1"	"29"	"7"	"14"	"7"	"307"	"34.9"	"9.57"	"2424.80"	"31.13"	"5"	"6"	""	"other membranes;mitochondrion;ER/Golgi;nucleus;other cell component"	""	"Pf13855"	"55379"	"ENSG00000108829"	"LRRC59"	"B2RE83; D3DTX8; hsa:55379; Q96AG4; Q9P189"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"877.3"	"926.3"	"885.2"	"771.0"	"878.3"	"903.4"	"1077.9"	"1404.8"	"2748.1"	"5247.9"	"6129.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31689"	"DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2"	"21"	"6"	"12"	"5"	"397"	"44.8"	"7.08"	"1645.69"	"31.06"	"5"	"5"	"protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00226, Pf00684, Pf01556"	"3301"	"ENSG00000086061"	"DNAJA1"	"hsa:3301; P31689; Q5T7Q0; Q86TL9"	"VEGFA-VEGFR2 signaling; Exercise-induced circadian regulation"	"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand"	"3"	"1"	"316.8"	"347.6"	"370.5"	"361.7"	"398.8"	"353.1"	"462.7"	"612.6"	"1334.6"	"2518.9"	"3443.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60256"	"Phosphoribosyl pyrophosphate synthase-associated protein 2 OS=Homo sapiens OX=9606 GN=PRPSAP2 PE=1 SV=1"	"22"	"8"	"18"	"8"	"369"	"40.9"	"7.44"	"3112.87"	"31.00"	"7"	"7"	"other metabolic processes;developmental processes"	"other cell component"	"enzyme regulator activity;other molecular function"	"Pf13793, Pf14572"	"5636"	"ENSG00000141127"	"PRPSAP2"	"B4E1M8; B4E329; B7ZKZ1; E7EMY2; hsa:5636; O60256; Q6IAS2"	""	""	"0"	"0"	"260.8"	"234.2"	"309.9"	"250.1"	"299.6"	"281.2"	"393.0"	"692.2"	"1869.0"	"3695.4"	"5463.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22033"	"Methylmalonyl-CoA mutase, mitochondrial OS=Homo sapiens OX=9606 GN=MMUT PE=1 SV=4"	"15"	"9"	"17"	"9"	"750"	"83.1"	"6.93"	"2969.82"	"30.79"	"8"	"9"	"other metabolic processes;developmental processes;other biological processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf01642, Pf02310"	"4594"	"ENSG00000146085"	"MMUT"	"A8K953; hsa:4594; P22033; Q5SYZ3; Q96B11; Q9UD64"	"Vitamin B12 metabolism; Amino acid metabolism"	"Propionyl-CoA catabolism; Defective MMAA causes MMA, cblA type; Defective MUT causes MMAM; Cobalamin (Cbl) metabolism"	"6"	"0"	"140.9"	"155.3"	"167.6"	"158.1"	"199.5"	"199.9"	"341.3"	"717.5"	"1604.2"	"2919.4"	"4770.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9ULC4"	"Malignant T-cell-amplified sequence 1 OS=Homo sapiens OX=9606 GN=MCTS1 PE=1 SV=1"	"48"	"6"	"14"	"6"	"181"	"20.5"	"8.82"	"2857.78"	"30.73"	"6"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"other cell component"	"nucleic acid binding activity"	"Pf01472, Pf17832"	"28985"	"ENSG00000232119; ENSG00000288295"	"MCTS1"	"B4DGY2; hsa:28985; Q502X6; Q9ULC4"	""	""	"0"	"0"	"107.8"	"91.4"	"134.6"	"110.9"	"122.4"	"128.2"	"144.4"	"218.7"	"1570.0"	"3724.3"	"4527.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13185"	"Chromobox protein homolog 3 OS=Homo sapiens OX=9606 GN=CBX3 PE=1 SV=4"	"33"	"5"	"11"	"4"	"183"	"20.8"	"5.33"	"1770.80"	"30.60"	"2"	"4"	"cell organization and biogenesis;stress response;other biological processes"	"other membranes;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00385, Pf01393"	"11335"	"ENSG00000122565"	"CBX3"	"hsa:11335; Q13185; Q96CD7; Q99409; Q9BVS3; Q9P0Z6"	"Exercise-induced circadian regulation; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; NIPBL role in DNA damage - Cornelia de Lange syndrome"	"RNA Polymerase I Promoter Escape; Transcriptional Regulation by E2F6; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"	"6"	"2"	"552.9"	"525.2"	"638.2"	"555.0"	"568.0"	"587.3"	"659.9"	"732.1"	"1026.7"	"2515.8"	"8601.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q04917"	"14-3-3 protein eta OS=Homo sapiens OX=9606 GN=YWHAH PE=1 SV=4"	"22"	"5"	"15"	"3"	"246"	"28.2"	"4.84"	"2698.70"	"30.53"	"4"	"5"	"other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00244"	"7533"	"ENSG00000128245"	"YWHAH"	"hsa:7533; Q04917"	"Cell cycle; Myometrial relaxation and contraction pathways; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"TP53 Regulates Metabolic Genes; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RHO GTPases activate PKNs; Translocation of SLC2A4 (GLUT4) to the plasma membrane; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Activation of BAD and translocation to mitochondria"	"11"	"0"	"417.5"	"467.4"	"405.2"	"367.4"	"427.8"	"477.2"	"577.5"	"692.7"	"905.8"	"1435.9"	"1954.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13428"	"Treacle protein OS=Homo sapiens OX=9606 GN=TCOF1 PE=1 SV=3"	"8"	"12"	"21"	"12"	"1488"	"152.0"	"9.04"	"4939.87"	"30.51"	"12"	"9"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf03546"	"6949"	"ENSG00000070814"	"TCOF1"	"A0JLU0; B4E111; hsa:6949; Q13428; Q6SC72; Q7Z5W9; Q96A52; Q99408; Q99860"	""	""	"0"	"0"	"1699.4"	"1439.2"	"1715.0"	"1496.9"	"1640.3"	"1649.0"	"1912.9"	"2084.5"	"2991.9"	"4006.6"	"4885.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43684"	"Mitotic checkpoint protein BUB3 OS=Homo sapiens OX=9606 GN=BUB3 PE=1 SV=1"	"23"	"8"	"18"	"8"	"328"	"37.1"	"6.84"	"3556.49"	"30.48"	"8"	"8"	"cell cycle OR cell proliferation;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00400"	"9184"	"ENSG00000154473"	"BUB3"	"A6NJ42; B2R6E7; D3DRE9; hsa:9184; O43684; O43685"	"Cell cycle; Regulation of sister chromatid separation at the metaphase-anaphase transition"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of mitotic proteins; APC-Cdc20 mediated degradation of Nek2A"	"12"	"0"	"989.2"	"867.9"	"971.5"	"786.0"	"954.2"	"900.1"	"1128.9"	"1430.1"	"2609.8"	"5099.1"	"6644.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6PKG0"	"La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2"	"12"	"10"	"17"	"10"	"1096"	"123.4"	"8.82"	"3109.75"	"30.41"	"8"	"9"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf05383"	"23367"	"ENSG00000155506"	"LARP1"	"hsa:23367; O94836; Q6PKG0; Q8N4M2; Q8NB73; Q9UFD7"	"Perturbations to host-cell autophagy, induced by SARS-CoV-2 proteins; SARS-CoV-2 innate immunity evasion and cell-specific immune response; Network map of SARS-CoV-2 signaling pathway"	"SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"4"	"0"	"998.0"	"951.0"	"1072.5"	"946.6"	"1089.5"	"1087.6"	"1176.7"	"1495.7"	"2213.0"	"3927.3"	"5339.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P258"	"Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2"	"19"	"8"	"16"	"8"	"522"	"56.0"	"8.78"	"3511.13"	"30.35"	"8"	"6"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00415"	"55920"	"ENSG00000179051; ENSG00000281540"	"RCC2"	"hsa:55920; Q8IVL9; Q9BSN6; Q9NPV8; Q9P258"	""	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"6"	"0"	"568.7"	"585.0"	"528.0"	"449.5"	"540.2"	"548.2"	"686.3"	"798.5"	"1450.5"	"3371.6"	"4262.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6PD62"	"RNA polymerase-associated protein CTR9 homolog OS=Homo sapiens OX=9606 GN=CTR9 PE=1 SV=1"	"7"	"7"	"12"	"7"	"1173"	"133.4"	"6.77"	"1916.58"	"30.32"	"5"	"6"	"cell-cell signaling;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf13181"	"9646"	"ENSG00000198730"	"CTR9"	"D3DQV8; hsa:9646; Q15015; Q6PD62"	"Endoderm differentiation"	"E3 ubiquitin ligases ubiquitinate target proteins; RNA Polymerase II Pre-transcription Events; Formation of RNA Pol II elongation complex"	"5"	"0"	"382.3"	"416.6"	"356.6"	"345.9"	"366.7"	"412.6"	"466.2"	"598.2"	"877.9"	"1541.9"	"2208.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60231"	"Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2"	"12"	"8"	"15"	"8"	"1041"	"119.2"	"6.80"	"2565.32"	"30.20"	"6"	"8"	"RNA metabolism OR transcription;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"8449"	"ENSG00000204560; ENSG00000206486; ENSG00000226171; ENSG00000231377; ENSG00000233049; ENSG00000233418; ENSG00000233561"	"DHX16"	"hsa:8449; O60231; O60322; Q5JP45; Q969X7; Q96QC1"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"263.2"	"237.4"	"278.8"	"267.2"	"266.3"	"281.4"	"348.5"	"419.3"	"1410.8"	"2025.4"	"2498.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15637"	"Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4"	"13"	"6"	"16"	"6"	"639"	"68.3"	"8.98"	"2982.75"	"30.14"	"5"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"translational apparatus;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf00098, Pf16275"	"7536"	"ENSG00000168066"	"SF1"	"B7Z1Q1; C9JJE2; hsa:7536; Q14818; Q14819; Q15637; Q15913; Q8IY00; Q92744; Q92745; Q969H7; Q9BW01; Q9UEI0"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"873.3"	"746.1"	"942.1"	"780.9"	"895.9"	"878.8"	"1068.3"	"1222.2"	"2100.4"	"3226.8"	"4529.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6NZY4"	"Zinc finger CCHC domain-containing protein 8 OS=Homo sapiens OX=9606 GN=ZCCHC8 PE=1 SV=2"	"14"	"7"	"15"	"7"	"707"	"78.5"	"4.87"	"3179.96"	"30.14"	"7"	"6"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00098, Pf04046"	"55596"	"ENSG00000033030"	"ZCCHC8"	"hsa:55596; Q6NZY4; Q7L2P6; Q8N2K5; Q96SK7; Q9NSS2; Q9NSS3"	""	""	"0"	"0"	"516.5"	"496.7"	"575.4"	"521.2"	"559.5"	"558.8"	"642.1"	"763.6"	"1055.3"	"1791.6"	"2416.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35241"	"Radixin OS=Homo sapiens OX=9606 GN=RDX PE=1 SV=1"	"20"	"13"	"25"	"3"	"583"	"68.5"	"6.37"	"5385.19"	"30.09"	"13"	"9"	"cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf00769, Pf09379, Pf09380, Pf20492"	"5962"	"ENSG00000137710"	"RDX"	"A7YIJ8; A7YIK0; A7YIK3; B7Z9U6; F5H1A7; hsa:5962; P35241; Q86Y61"	"Regulation of actin cytoskeleton"	"Recycling pathway of L1; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea"	"4"	"0"	"648.5"	"564.7"	"664.1"	"491.0"	"611.0"	"701.2"	"824.1"	"874.2"	"1671.9"	"1670.0"	"1483.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P68400"	"Casein kinase II subunit alpha OS=Homo sapiens OX=9606 GN=CSNK2A1 PE=1 SV=1"	"17"	"7"	"15"	"6"	"391"	"45.1"	"7.74"	"1955.05"	"29.99"	"4"	"7"	"cell-cell signaling;cell cycle OR cell proliferation;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"1457"	"ENSG00000101266"	"CSNK2A1"	"B4DYS6; D3DVV8; hsa:1457; P19138; P20426; P68400; Q14013; Q5U065"	"Alzheimer's disease and miRNA effects; TNF-alpha signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; lncRNA in canonical Wnt signaling and colorectal cancer; Breast cancer pathway; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Translation inhibitors in chronically activated PDGFRA cells; Measles virus infection; Pleural mesothelioma; Alzheimer's disease"	"Regulation of PTEN stability and activity; KEAP1-NFE2L2 pathway; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Regulation of TP53 Activity through Phosphorylation; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; WNT mediated activation of DVL; Signal transduction by L1; Receptor Mediated Mitophagy; Condensation of Prometaphase Chromosomes; Synthesis of PC"	"21"	"1"	"311.7"	"292.9"	"348.2"	"294.5"	"310.9"	"347.7"	"426.2"	"522.8"	"937.7"	"2391.3"	"4225.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y314"	"Nitric oxide synthase-interacting protein OS=Homo sapiens OX=9606 GN=NOSIP PE=1 SV=1"	"38"	"8"	"14"	"8"	"301"	"33.2"	"8.82"	"2218.80"	"29.99"	"6"	"8"	"other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf15906"	"51070"	"ENSG00000142546"	"NOSIP"	"hsa:51070; Q96FD2; Q9Y314"	""	"NOSIP mediated eNOS trafficking"	"1"	"0"	"335.9"	"335.4"	"367.4"	"341.5"	"382.4"	"380.4"	"460.0"	"594.2"	"1477.9"	"1912.2"	"2110.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43143"	"Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2"	"9"	"7"	"13"	"7"	"795"	"90.9"	"7.46"	"2738.95"	"29.93"	"6"	"7"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"1665"	"ENSG00000109606"	"DHX15"	"hsa:1665; O43143; Q9NQT7"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"265.8"	"259.9"	"316.9"	"268.6"	"335.8"	"300.4"	"360.1"	"532.0"	"901.8"	"2048.5"	"3440.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43768"	"Alpha-endosulfine OS=Homo sapiens OX=9606 GN=ENSA PE=1 SV=1"	"64"	"7"	"15"	"7"	"121"	"13.4"	"7.24"	"2721.87"	"29.88"	"6"	"7"	"cell cycle OR cell proliferation;other biological processes"	"nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf04667"	"2029"	"ENSG00000143420"	"ENSA"	"A8K1Z9; E9PB69; hsa:2029; O43768; Q5T5H2; Q68D48; Q6FHW0; Q6IAM4; Q6NUL2; Q6VUC6; Q6VUC7; Q6VUC8; Q6VUC9; Q6VUD0; Q6VUD1; Q9NRZ0"	""	"MASTL Facilitates Mitotic Progression"	"1"	"0"	"245.1"	"186.1"	"252.2"	"248.3"	"258.7"	"248.2"	"306.3"	"388.9"	"2403.6"	"6309.4"	"8609.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q53GS9"	"U4/U6.U5 tri-snRNP-associated protein 2 OS=Homo sapiens OX=9606 GN=USP39 PE=1 SV=2"	"16"	"9"	"18"	"8"	"565"	"65.3"	"8.91"	"3165.03"	"29.86"	"9"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00443, Pf02148"	"10713"	"ENSG00000168883"	"USP39"	"A8K086; B3KM40; B4DHT4; D6W5L4; G5E9H0; hsa:10713; Q53GS9; Q6NX47; Q96RK9; Q9BV89; Q9H381; Q9P050; Q9Y310"	""	"mRNA Splicing - Major Pathway"	"1"	"1"	"728.8"	"564.6"	"691.2"	"579.5"	"701.8"	"659.3"	"787.2"	"975.8"	"1632.0"	"3291.7"	"4036.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14126"	"Desmoglein-2 OS=Homo sapiens OX=9606 GN=DSG2 PE=1 SV=2"	"9"	"7"	"14"	"7"	"1118"	"122.2"	"5.24"	"2855.35"	"29.84"	"7"	"7"	"cell adhesion;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00028"	"1829"	"ENSG00000046604"	"DSG2"	"hsa:1829; Q14126; Q4KKU6"	"Arrhythmogenic right ventricular cardiomyopathy; GDNF signaling"	"Formation of the cornified envelope; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; Apoptotic cleavage of cell adhesion  proteins"	"8"	"0"	"428.7"	"447.9"	"467.5"	"410.3"	"420.8"	"458.6"	"543.8"	"653.8"	"1292.8"	"2483.9"	"3599.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14152"	"Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1"	"8"	"10"	"17"	"10"	"1382"	"166.5"	"6.79"	"2766.85"	"29.84"	"8"	"9"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;translational apparatus;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf01399"	"8661"	"ENSG00000107581"	"EIF3A"	"B1AMV5; B4DYS1; F5H335; hsa:8661; O00653; Q14152; Q15778"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"8"	"0"	"425.8"	"391.2"	"441.5"	"400.4"	"440.0"	"428.7"	"481.3"	"630.0"	"1107.8"	"2184.3"	"5561.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q06587"	"E3 ubiquitin-protein ligase RING1 OS=Homo sapiens OX=9606 GN=RING1 PE=1 SV=2"	"21"	"5"	"10"	"4"	"406"	"42.4"	"5.62"	"1988.59"	"29.78"	"3"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00097, Pf16207"	"6015"	"ENSG00000204227; ENSG00000206287; ENSG00000226788; ENSG00000228520; ENSG00000231115; ENSG00000235107"	"RING1"	"A8JZZ0; hsa:6015; Q06587; Q5JP96; Q5SQW2; Q86V19"	"Pleural mesothelioma; Notch signaling pathway"	"Oxidative Stress Induced Senescence; SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6"	"11"	"1"	"360.4"	"307.8"	"354.6"	"322.8"	"352.3"	"344.9"	"432.3"	"556.3"	"954.2"	"1573.5"	"2274.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60841"	"Eukaryotic translation initiation factor 5B OS=Homo sapiens OX=9606 GN=EIF5B PE=1 SV=4"	"8"	"8"	"11"	"8"	"1220"	"138.7"	"5.49"	"1786.82"	"29.77"	"5"	"6"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03144, Pf11987"	"9669"	"ENSG00000158417"	"EIF5B"	"hsa:9669; O60841; O95805; Q53RV7; Q53SI8; Q9UF81; Q9UMN7"	"Translation factors; Ciliary landscape"	"GTP hydrolysis and joining of the 60S ribosomal subunit"	"3"	"0"	"321.6"	"254.5"	"349.6"	"311.5"	"319.2"	"342.7"	"419.1"	"587.5"	"1812.8"	"2952.5"	"3034.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62736"	"Actin, aortic smooth muscle OS=Homo sapiens OX=9606 GN=ACTA2 PE=1 SV=1"	"18"	"7"	"18"	"1"	"377"	"42.0"	"5.39"	"3447.59"	"29.77"	"6"	"6"	"developmental processes;other biological processes"	"extracellular matrix;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00022"	"59"	"ENSG00000107796"	"ACTA2"	"B2R8A4; hsa:59; P03996; P04108; P62736; Q6FI19"	"Myometrial relaxation and contraction pathways; Striated muscle contraction pathway; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; 22q11.2 copy number variation syndrome; IL-18 signaling pathway; Regucalcin in proximal tubule epithelial kidney cells; Angiotensin II receptor type 1 pathway; Pleural mesothelioma; CCL18 signaling pathway; Urotensin-II-mediated signaling pathway; Markers of kidney cell lineage; Comprehensive IL-17A signaling; IL-26 signaling pathways; A network map of Macrophage-stimulating protein (MSP) signaling"	"Smooth Muscle Contraction; NOTCH4 Intracellular Domain Regulates Transcription"	"16"	"0"	"94.9"	"131.0"	"97.1"	"101.4"	"98.0"	"80.0"	"125.0"	"172.3"	"322.3"	"636.5"	"950.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H9Y6"	"DNA-directed RNA polymerase I subunit RPA2 OS=Homo sapiens OX=9606 GN=POLR1B PE=1 SV=2"	"9"	"7"	"15"	"7"	"1135"	"128.1"	"7.83"	"2775.83"	"29.71"	"7"	"7"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00562, Pf04560, Pf04561, Pf04563, Pf04565, Pf06883"	"84172"	"ENSG00000125630"	"POLR1B"	"B7Z6Y7; B7Z823; F5GZX4; F8W898; hsa:84172; Q2TAM4; Q585T5; Q6ZRR2; Q9H9D3; Q9H9Y6"	"Pyrimidine metabolism; Eukaryotic transcription initiation; 2q13 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"8"	"0"	"105.7"	"97.1"	"139.4"	"103.1"	"110.9"	"116.5"	"167.1"	"286.9"	"951.2"	"1964.5"	"2811.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75494"	"Serine/arginine-rich splicing factor 10 OS=Homo sapiens OX=9606 GN=SRSF10 PE=1 SV=1"	"24"	"7"	"13"	"5"	"262"	"31.3"	"11.27"	"2062.74"	"29.62"	"4"	"7"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"10772"	"ENSG00000188529"	"SRSF10"	"A6NFM6; A6NI42; A6NIU7; B4DJP9; hsa:10772; O60572; O75494; Q5JRH9; Q5JRI0; Q5JRI2; Q5JRI3; Q5JRI4; Q96G09; Q96P17"	"mRNA processing"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"3"	"2"	"407.2"	"412.9"	"431.7"	"422.3"	"421.3"	"403.2"	"511.6"	"653.1"	"945.5"	"1632.3"	"2631.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75521"	"Enoyl-CoA delta isomerase 2, mitochondrial OS=Homo sapiens OX=9606 GN=ECI2 PE=1 SV=4"	"23"	"6"	"10"	"6"	"394"	"43.6"	"9.00"	"1730.41"	"29.59"	"4"	"6"	"other metabolic processes"	"cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00378, Pf00887"	"10455"	"ENSG00000198721"	"ECI2"	"hsa:10455; O75521; Q5JYK5; Q5JYK7; Q7L124; Q8N0X0; Q9BUE9; Q9H0T9; Q9NQH1; Q9NYH7; Q9UN55"	""	""	"0"	"0"	"384.4"	"379.8"	"396.1"	"329.8"	"451.5"	"415.3"	"494.7"	"593.0"	"1429.2"	"3559.4"	"5550.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2D5"	"A-kinase anchor protein 2 OS=Homo sapiens OX=9606 GN=AKAP2 PE=1 SV=3"	"9"	"6"	"14"	"6"	"859"	"94.6"	"5.11"	"3267.76"	"29.55"	"6"	"6"	""	""	""	"Pf15304"	"445815"	""	"AKAP2"	"B1ALX9; B2RTU4; B3KQ00; B4DTZ2; B7ZW07; B9EJB5; Q9UG26; Q9Y2D5"	""	""	"0"	"0"	"569.7"	"538.6"	"580.6"	"510.8"	"584.2"	"612.4"	"638.5"	"679.2"	"1004.2"	"2101.7"	"2812.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46060"	"Ran GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RANGAP1 PE=1 SV=1"	"17"	"8"	"14"	"8"	"587"	"63.5"	"4.68"	"2402.45"	"29.55"	"6"	"8"	"protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf07834, Pf13516"	"5905"	"ENSG00000100401"	"RANGAP1"	"hsa:5905; P46060; Q96JJ2"	"22q11.2 copy number variation syndrome; IL-18 signaling pathway"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Rev-mediated nuclear export of HIV RNA; SUMOylation of DNA replication proteins; Postmitotic nuclear pore complex (NPC) reformation; SUMOylation of nuclear envelope proteins"	"12"	"0"	"380.8"	"343.8"	"433.1"	"364.5"	"397.8"	"395.3"	"462.0"	"591.9"	"927.7"	"1570.1"	"2298.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51659"	"Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3"	"13"	"9"	"18"	"9"	"736"	"79.6"	"8.84"	"3948.92"	"29.52"	"9"	"8"	"other metabolic processes;developmental processes"	"cytosol;other cytoplasmic organelle"	"other molecular function"	"Pf00106, Pf01575, Pf02036"	"3295"	"ENSG00000133835"	"HSD17B4"	"B4DNV1; B4DVS5; E9PB82; F5HE57; hsa:3295; P51659"	"Androgen receptor network in prostate cancer; Steroid biosynthesis; Disorders of bile acid synthesis and biliary transport; Primary ovarian insufficiency"	"TYSND1 cleaves peroxisomal proteins; Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol; alpha-linolenic acid (ALA) metabolism; Beta-oxidation of pristanoyl-CoA; Beta-oxidation of very long chain fatty acids"	"10"	"0"	"306.3"	"314.6"	"350.7"	"299.5"	"318.5"	"323.2"	"408.5"	"585.1"	"1292.1"	"2715.4"	"4243.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31939"	"Bifunctional purine biosynthesis protein PURH OS=Homo sapiens OX=9606 GN=ATIC PE=1 SV=3"	"18"	"9"	"11"	"9"	"592"	"64.6"	"6.71"	"636.85"	"29.25"	"2"	"9"	"other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol"	"other molecular function"	"Pf01808, Pf02142"	"471"	"ENSG00000138363"	"ATIC"	"A8K202; E9PBU3; hsa:471; P31939; Q13856; Q53S28"	"One-carbon metabolism"	"Signaling by ALK fusions and activated point mutants; Purine ribonucleoside monophosphate biosynthesis"	"3"	"0"	"126.3"	"102.8"	"189.5"	"150.3"	"153.8"	"162.4"	"187.8"	"228.8"	"389.7"	"1591.2"	"5437.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61160"	"Actin-related protein 2 OS=Homo sapiens OX=9606 GN=ACTR2 PE=1 SV=1"	"22"	"8"	"17"	"8"	"394"	"44.7"	"6.74"	"3267.63"	"29.25"	"8"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00022"	"10097"	"ENSG00000138071"	"ACTR2"	"B2RCP5; D6W5F4; E9PF41; hsa:10097; O15142; P61160; Q96C82"	"Physico-chemical features and toxicity-associated pathways; Embryonic stem cell pluripotency pathways"	"Regulation of actin dynamics for phagocytic cup formation; Neutrophil degranulation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Clathrin-mediated endocytosis; EPHB-mediated forward signaling"	"8"	"0"	"390.5"	"339.2"	"465.6"	"406.1"	"475.4"	"404.6"	"499.8"	"780.1"	"2974.3"	"4362.0"	"5214.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75150"	"E3 ubiquitin-protein ligase BRE1B OS=Homo sapiens OX=9606 GN=RNF40 PE=1 SV=5"	"7"	"8"	"16"	"5"	"1001"	"113.6"	"6.29"	"3312.97"	"29.24"	"8"	"8"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00097"	"9810"	"ENSG00000103549"	"RNF40"	"A0A024QZG0; hsa:9810; O75150; Q6AHZ6; Q6N005; Q7L3T6; Q8N615; Q96T18; Q9BSV9; Q9HC82"	"ATM signaling in development and disease"	"E3 ubiquitin ligases ubiquitinate target proteins"	"2"	"0"	"392.7"	"356.8"	"415.6"	"349.4"	"404.7"	"408.4"	"473.1"	"538.3"	"1307.6"	"2202.4"	"3008.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49589"	"Cysteine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=CARS1 PE=1 SV=3"	"12"	"7"	"11"	"7"	"748"	"85.4"	"6.76"	"1588.47"	"29.18"	"4"	"7"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01406"	"833"	"ENSG00000110619; ENSG00000278191"	"CARS1"	"hsa:833; P49589; Q53XI8; Q5HYE4; Q9HD24; Q9HD25"	""	"Cytosolic tRNA aminoacylation; Signaling by ALK fusions and activated point mutants"	"2"	"0"	"123.2"	"117.2"	"153.4"	"146.1"	"147.3"	"140.1"	"167.9"	"223.6"	"740.4"	"2124.0"	"4590.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15555"	"Microtubule-associated protein RP/EB family member 2 OS=Homo sapiens OX=9606 GN=MAPRE2 PE=1 SV=1"	"22"	"5"	"13"	"5"	"327"	"37.0"	"5.57"	"2031.67"	"29.18"	"4"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf03271"	"10982"	"ENSG00000166974"	"MAPRE2"	"B2RE21; B3KR39; B4DJV4; B7Z2L3; E9PHR3; F5H1V8; G5E9I6; hsa:10982; Q15555; Q9UQ33"	"Ciliary landscape"	""	"1"	"0"	"151.1"	"119.4"	"162.8"	"148.8"	"144.7"	"181.6"	"205.1"	"274.4"	"1119.5"	"2364.7"	"2644.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13283"	"Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1"	"22"	"7"	"13"	"7"	"466"	"52.1"	"5.52"	"2133.85"	"29.16"	"6"	"7"	"cell organization and biogenesis;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00076, Pf02136"	"10146"	"ENSG00000145907"	"G3BP1"	"hsa:10146; Q13283; Q5HYE9"	""	"SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"1"	"0"	"269.5"	"277.8"	"263.7"	"250.8"	"280.3"	"268.1"	"328.3"	"433.8"	"658.7"	"1077.0"	"1588.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46939"	"Utrophin OS=Homo sapiens OX=9606 GN=UTRN PE=1 SV=2"	"3"	"8"	"14"	"7"	"3433"	"394.2"	"5.33"	"2858.85"	"29.12"	"7"	"7"	"cell-cell signaling;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00307, Pf00435, Pf00569, Pf09068, Pf09069"	"7402"	"ENSG00000152818"	"UTRN"	"hsa:7402; P46939; Q5SYY1; Q5SZ57; Q9UJ40"	"Primary focal segmental glomerulosclerosis (FSGS)"	"EGR2 and SOX10-mediated initiation of Schwann cell myelination"	"2"	"1"	"218.1"	"201.1"	"248.4"	"198.1"	"259.0"	"251.8"	"286.1"	"337.9"	"658.2"	"1196.4"	"1652.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23588"	"Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2"	"13"	"6"	"11"	"6"	"611"	"69.1"	"5.73"	"2178.71"	"29.06"	"5"	"6"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus"	"nucleic acid binding activity"	"Pf00076"	"1975"	"ENSG00000063046"	"EIF4B"	"B4DS13; hsa:1975; P23588; Q4G0E3; Q53HQ2; Q6GPH5; Q6IB46; Q8WYK5"	"Translation factors; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Translation inhibitors in chronically activated PDGFRA cells; Perturbations to host-cell autophagy, induced by SARS-CoV-2 proteins; Pleural mesothelioma; Interferon type I signaling pathways"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Deadenylation of mRNA; mTORC1-mediated signalling"	"14"	"0"	"145.7"	"129.5"	"201.7"	"174.0"	"179.1"	"187.7"	"216.1"	"236.1"	"764.1"	"2683.8"	"4077.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q09028"	"Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3"	"20"	"9"	"17"	"3"	"425"	"47.6"	"4.89"	"2929.02"	"29.00"	"8"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400, Pf12265"	"5928"	"ENSG00000162521"	"RBBP4"	"B2R6G9; B4DRH0; D3DPQ3; hsa:5928; P31149; Q09028; Q53H02; Q96BV9"	"Retinoblastoma gene in cancer; Interactome of polycomb repressive complex 2 (PRC2) ; Tumor suppressor activity of SMARCB1; Epithelial to mesenchymal transition in colorectal cancer; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; Pleural mesothelioma; DYRK1A involvement regarding cell proliferation in brain development"	"Activation of anterior HOX genes in hindbrain development during early embryogenesis; HCMV Early Events; RNA Polymerase I Transcription Initiation; Potential therapeutics for SARS; Deposition of new CENPA-containing nucleosomes at the centromere; Oxidative Stress Induced Senescence; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6; HDACs deacetylate histones; PKMTs methylate histone lysines; PRC2 methylates histones and DNA; Defective pyroptosis; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; G1/S-Specific Transcription; Regulation of TP53 Activity through Acetylation; Polo-like kinase mediated events; Cyclin E associated events during G1/S transition ; Transcription of E2F targets under negative control by DREAM complex; Cyclin A:Cdk2-associated events at S phase entry; Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"	"28"	"7"	"1102.7"	"1098.5"	"1158.3"	"1025.9"	"1144.6"	"1210.1"	"1367.8"	"1709.8"	"2551.0"	"4561.6"	"6890.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55209"	"Nucleosome assembly protein 1-like 1 OS=Homo sapiens OX=9606 GN=NAP1L1 PE=1 SV=1"	"18"	"6"	"14"	"4"	"391"	"45.3"	"4.46"	"2593.53"	"28.96"	"6"	"6"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00956"	"4673"	"ENSG00000187109"	"NAP1L1"	"B3KNT8; B3KV44; hsa:4673; P55209"	"VEGFA-VEGFR2 signaling; Overlap between signal transduction pathways contributing to LMNA laminopathies"	""	"2"	"0"	"207.0"	"200.7"	"201.9"	"182.5"	"225.0"	"238.8"	"284.8"	"350.4"	"667.3"	"1126.8"	"1841.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06454"	"Prothymosin alpha OS=Homo sapiens OX=9606 GN=PTMA PE=1 SV=2"	"14"	"3"	"13"	"3"	"111"	"12.2"	"3.78"	"3956.19"	"28.92"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf03247"	"5757"	"ENSG00000187514"	"PTMA"	"hsa:5757; P06454; Q15249; Q15592"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"1173.5"	"1088.7"	"1179.2"	"1071.1"	"1154.4"	"1279.5"	"1373.5"	"1203.9"	"1175.2"	"1111.8"	"1062.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16629"	"Serine/arginine-rich splicing factor 7 OS=Homo sapiens OX=9606 GN=SRSF7 PE=1 SV=1"	"35"	"7"	"13"	"7"	"238"	"27.4"	"11.82"	"1213.39"	"28.78"	"4"	"7"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6432"	"ENSG00000115875"	"SRSF7"	"B4DLU6; G5E9M3; hsa:6432; Q16629; Q564D3"	"mRNA processing"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"7"	"0"	"785.1"	"893.3"	"817.5"	"756.2"	"839.9"	"773.6"	"1029.2"	"1320.5"	"1654.7"	"2195.6"	"3299.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P27348"	"14-3-3 protein theta OS=Homo sapiens OX=9606 GN=YWHAQ PE=1 SV=1"	"24"	"5"	"17"	"3"	"245"	"27.7"	"4.78"	"3340.17"	"28.77"	"5"	"5"	"transport;signal transduction;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00244"	"10971"	"ENSG00000134308"	"YWHAQ"	"D6W4Z5; hsa:10971; P27348; Q567U5; Q5TZU8; Q9UP48"	"Cell cycle; Pathogenic Escherichia coli infection; Primary focal segmental glomerulosclerosis (FSGS); IL-3 signaling pathway; Myometrial relaxation and contraction pathways; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-YAP signaling; Leukocyte-intrinsic Hippo pathway functions; Hepatitis B infection; Opioid receptor pathways; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Regulation of localization of FOXO transcription factors; TP53 Regulates Metabolic Genes; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Activation of BAD and translocation to mitochondria"	"20"	"0"	"136.4"	"159.3"	"141.5"	"123.9"	"155.7"	"150.6"	"186.5"	"253.5"	"612.1"	"1300.4"	"1770.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P40222"	"Alpha-taxilin OS=Homo sapiens OX=9606 GN=TXLNA PE=1 SV=3"	"25"	"11"	"19"	"10"	"546"	"61.9"	"6.52"	"4195.72"	"28.70"	"11"	"8"	"transport;other biological processes"	"non-structural extracellular;cytosol;other cell component"	"other molecular function"	"Pf09728"	"200081"	"ENSG00000084652"	"TXLNA"	"D3DPP6; hsa:200081; P40222; Q5TFJ6; Q66K62; Q86T54; Q86T85; Q86T86; Q86Y86; Q86YW3; Q8N2Y3"	""	"Other interleukin signaling"	"1"	"1"	"606.7"	"501.7"	"680.3"	"573.2"	"639.2"	"603.2"	"799.4"	"1229.0"	"2503.9"	"3930.4"	"4210.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2W2"	"WW domain-binding protein 11 OS=Homo sapiens OX=9606 GN=WBP11 PE=1 SV=1"	"12"	"6"	"13"	"6"	"641"	"70.0"	"8.38"	"2313.77"	"28.68"	"5"	"6"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09429"	"51729"	"ENSG00000084463"	"WBP11"	"hsa:51729; Q96AY8; Q9Y2W2"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"326.7"	"310.2"	"355.8"	"312.7"	"346.5"	"347.8"	"387.0"	"481.7"	"721.0"	"1253.5"	"1487.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49736"	"DNA replication licensing factor MCM2 OS=Homo sapiens OX=9606 GN=MCM2 PE=1 SV=4"	"11"	"7"	"12"	"7"	"904"	"101.8"	"5.52"	"2326.97"	"28.63"	"5"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf12619, Pf14551, Pf17207, Pf17855"	"4171"	"ENSG00000073111"	"MCM2"	"hsa:4171; P49736; Q14577; Q15023; Q8N2V1; Q969W7; Q96AE1; Q9BRM7"	"Cell cycle; Ciliary landscape; G1 to S cell cycle control; DNA replication; 1p36 copy number variation syndrome"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"11"	"0"	"109.2"	"114.2"	"113.7"	"104.5"	"114.5"	"103.4"	"127.4"	"216.6"	"336.3"	"589.1"	"1431.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62136"	"Serine/threonine-protein phosphatase PP1-alpha catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CA PE=1 SV=1"	"27"	"7"	"15"	"3"	"330"	"37.5"	"6.33"	"2784.17"	"28.59"	"6"	"7"	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00149, Pf16891"	"5499"	"ENSG00000172531"	"PPP1CA"	"A6NNR3; B2R908; hsa:5499; P08129; P20653; P22802; P62136; Q07161"	"Sphingolipid pathway; Nicotine effect on dopaminergic neurons; Common pathways underlying drug addiction; Focal adhesion; VEGFA-VEGFR2 signaling; Hippo-Merlin signaling dysregulation; Fragile X syndrome; Netrin-UNC5B signaling pathway; Neuroinflammation and glutamatergic signaling"	"Triglyceride catabolism; Circadian Clock; Downregulation of TGF-beta receptor signaling; DARPP-32 events"	"13"	"4"	"428.5"	"349.9"	"442.6"	"420.3"	"439.3"	"410.9"	"486.0"	"606.0"	"1347.3"	"2932.5"	"4046.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WYP5"	"Protein ELYS OS=Homo sapiens OX=9606 GN=AHCTF1 PE=1 SV=3"	"4"	"6"	"13"	"6"	"2266"	"252.3"	"6.60"	"2336.94"	"28.50"	"5"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf13934, Pf16687"	"25909"	"ENSG00000153207"	"AHCTF1"	"A6NGM0; A8MSG9; A8MZ86; hsa:25909; Q7Z4E3; Q8IZA4; Q8WYP5; Q96EH9; Q9Y4Q6"	"Gastric cancer network 2"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Postmitotic nuclear pore complex (NPC) reformation"	"8"	"0"	"281.5"	"246.3"	"308.5"	"256.8"	"278.1"	"269.8"	"327.4"	"377.2"	"610.7"	"1071.6"	"1513.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14927"	"Cytochrome b-c1 complex subunit 7 OS=Homo sapiens OX=9606 GN=UQCRB PE=1 SV=2"	"46"	"5"	"13"	"5"	"111"	"13.5"	"8.78"	"3077.23"	"28.48"	"5"	"5"	"other metabolic processes;transport"	"other membranes;mitochondrion"	""	"Pf02271"	"7381"	"ENSG00000156467"	"UQCRB"	"E5RJU0; hsa:7381; P14927; Q6FGD1"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex III assembly"	"Respiratory electron transport"	"4"	"0"	"680.7"	"745.6"	"677.1"	"707.0"	"708.1"	"683.3"	"861.0"	"1061.1"	"1663.9"	"2449.7"	"3811.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75369"	"Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2"	"4"	"7"	"11"	"6"	"2602"	"278.0"	"5.73"	"1796.08"	"28.40"	"4"	"7"	"cell organization and biogenesis;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00630"	"2317"	"ENSG00000136068"	"FLNB"	"B2ZZ83; B2ZZ84; B2ZZ85; C9JKE6; C9JMC4; hsa:2317; O75369; Q13706; Q59EC2; Q60FE7; Q6MZJ1; Q8WXS9; Q8WXT0; Q8WXT1; Q8WXT2; Q8WXT3; Q9NRB5; Q9NT26; Q9UEV9"	"Focal adhesion; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Ebola virus infection in host; NPHP1 deletion syndrome"	"ISG15 antiviral mechanism"	"6"	"0"	"91.8"	"87.2"	"105.0"	"82.0"	"96.8"	"96.3"	"116.6"	"188.9"	"312.4"	"548.9"	"928.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NFH4"	"Nucleoporin Nup37 OS=Homo sapiens OX=9606 GN=NUP37 PE=1 SV=1"	"25"	"7"	"15"	"7"	"326"	"36.7"	"5.92"	"3634.91"	"28.40"	"7"	"6"	"cell cycle OR cell proliferation;transport;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf00400"	"79023"	"ENSG00000075188"	"NUP37"	"hsa:79023; Q8NFH4; Q9H644"	""	"Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Regulation of HSF1-mediated heat shock response; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; ISG15 antiviral mechanism; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Vpr-mediated nuclear import of PICs; Transport of Mature mRNA derived from an Intron-Containing Transcript; tRNA processing in the nucleus; HCMV Late Events; HCMV Early Events; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); SARS-CoV-2 activates/modulates innate and adaptive immune responses; Postmitotic nuclear pore complex (NPC) reformation"	"35"	"0"	"607.6"	"592.9"	"668.4"	"508.4"	"702.0"	"759.9"	"854.6"	"1193.6"	"2167.3"	"3146.6"	"4108.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15185"	"Prostaglandin E synthase 3 OS=Homo sapiens OX=9606 GN=PTGES3 PE=1 SV=1"	"41"	"6"	"12"	"6"	"160"	"18.7"	"4.54"	"2741.76"	"28.37"	"6"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf04969"	"10728"	"ENSG00000110958"	"PTGES3"	"A8K7D0; B4DHP2; B4DP11; B4DP21; hsa:10728; Q15185; Q8WU70"	"Aryl hydrocarbon receptor pathway; Glucocorticoid receptor pathway; Nuclear receptors meta-pathway"	"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Estrogen-dependent gene expression; Potential therapeutics for SARS; HSF1 activation; Aryl hydrocarbon receptor signalling; Synthesis of Prostaglandins (PG) and Thromboxanes (TX); Attenuation phase"	"11"	"0"	"1557.7"	"1236.2"	"1702.8"	"1396.4"	"1399.7"	"1431.6"	"1895.3"	"1990.1"	"1973.2"	"1994.9"	"2293.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13242"	"Serine/arginine-rich splicing factor 9 OS=Homo sapiens OX=9606 GN=SRSF9 PE=1 SV=1"	"33"	"8"	"19"	"7"	"221"	"25.5"	"8.65"	"3553.62"	"28.36"	"8"	"7"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00076"	"8683"	"ENSG00000111786"	"SRSF9"	"hsa:8683; Q13242; Q52LD1"	"mRNA processing"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"6"	"0"	"1011.1"	"1144.4"	"1048.4"	"937.0"	"1029.4"	"876.8"	"1164.7"	"1499.9"	"1512.2"	"1945.1"	"3017.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P2I0"	"Cleavage and polyadenylation specificity factor subunit 2 OS=Homo sapiens OX=9606 GN=CPSF2 PE=1 SV=2"	"15"	"6"	"9"	"6"	"782"	"88.4"	"5.11"	"1378.97"	"28.29"	"3"	"6"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf07521, Pf10996, Pf13299, Pf16661"	"53981"	"ENSG00000165934"	"CPSF2"	"B3KME1; hsa:53981; Q6NSJ1; Q9H3W7; Q9P2I0"	"mRNA processing"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs; Transport of Mature mRNA Derived from an Intronless Transcript"	"6"	"0"	"233.8"	"200.0"	"272.9"	"212.5"	"228.3"	"224.7"	"301.8"	"336.1"	"538.9"	"892.9"	"1330.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P33993"	"DNA replication licensing factor MCM7 OS=Homo sapiens OX=9606 GN=MCM7 PE=1 SV=4"	"16"	"9"	"16"	"9"	"719"	"81.3"	"6.46"	"3766.91"	"28.27"	"9"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf14551, Pf17207, Pf17855"	"4176"	"ENSG00000166508"	"MCM7"	"A4D2A1; A4D2A2; E9PGN9; hsa:4176; P33993; Q15076; Q96D34; Q96GL1"	"miRNA regulation of DNA damage response; Cell cycle; Retinoblastoma gene in cancer; Ciliary landscape; G1 to S cell cycle control; DNA replication"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"12"	"0"	"608.3"	"570.1"	"659.5"	"607.1"	"626.2"	"600.1"	"736.2"	"885.0"	"1481.7"	"2984.3"	"6603.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13616"	"Cullin-1 OS=Homo sapiens OX=9606 GN=CUL1 PE=1 SV=2"	"10"	"7"	"12"	"7"	"776"	"89.6"	"8.00"	"1182.30"	"28.10"	"4"	"7"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00888, Pf10557"	"8454"	"ENSG00000055130"	"CUL1"	"D3DWG3; hsa:8454; O60719; Q08AL6; Q13616; Q8IYW1"	"Cell cycle; TNF-alpha signaling pathway; Parkin-ubiquitin proteasomal system pathway; Apoptosis-related network due to altered Notch3 in ovarian cancer; Glucocorticoid receptor pathway; Nuclear receptors meta-pathway; Pleural mesothelioma; Notch signaling pathway"	"Neddylation; Nuclear events stimulated by ALK signaling in cancer; Circadian Clock; Regulation of PLK1 Activity at G2/M Transition; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; SCF-beta-TrCP mediated degradation of Emi1; Degradation of beta-catenin by the destruction complex; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; NIK-->noncanonical NF-kB signaling; Orc1 removal from chromatin; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; SCF(Skp2)-mediated degradation of p27/p21; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Cyclin D associated events in G1; Regulation of BACH1 activity; MAP3K8 (TPL2)-dependent MAPK1/3 activation; NOTCH1 Intracellular Domain Regulates Transcription; Prolactin receptor signaling; Iron uptake and transport; Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling"	"40"	"0"	"277.3"	"273.0"	"316.0"	"230.9"	"304.7"	"311.9"	"340.5"	"493.8"	"2103.1"	"4434.4"	"5808.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P29966"	"Myristoylated alanine-rich C-kinase substrate OS=Homo sapiens OX=9606 GN=MARCKS PE=1 SV=4"	"25"	"7"	"14"	"7"	"332"	"31.5"	"4.45"	"2872.43"	"28.09"	"7"	"7"	"cell organization and biogenesis;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02063"	"4082"	"ENSG00000277443"	"MARCKS"	"E1P560; hsa:4082; P29966; Q2LA83; Q5TDB7"	"Brain-derived neurotrophic factor (BDNF) signaling pathway"	"Acetylcholine regulates insulin secretion"	"2"	"0"	"292.2"	"263.7"	"294.2"	"271.5"	"282.2"	"292.9"	"378.8"	"507.6"	"3426.8"	"5371.1"	"6095.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96FN4"	"Copine-2 OS=Homo sapiens OX=9606 GN=CPNE2 PE=1 SV=3"	"14"	"5"	"11"	"5"	"548"	"61.2"	"6.07"	"2213.05"	"27.97"	"4"	"5"	"other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00168, Pf07002"	"221184"	"ENSG00000140848"	"CPNE2"	"hsa:221184; Q68D19; Q719H8; Q86XP9; Q96FN4"	""	""	"0"	"0"	"82.6"	"79.7"	"97.8"	"77.5"	"92.1"	"87.1"	"107.6"	"133.3"	"431.3"	"2374.1"	"3952.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKX7"	"Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2"	"19"	"6"	"11"	"6"	"468"	"50.1"	"7.06"	"2332.48"	"27.93"	"5"	"5"	"transport"	"other membranes;nucleus"	""	"Pf00638, Pf08911"	"10762"	"ENSG00000093000"	"NUP50"	"B1AHA4; B2RB15; hsa:10762; O75644; Q8N6V5; Q9NPM9; Q9NPR6; Q9P1K5; Q9UKX7"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; SUMOylation of DNA replication proteins; Regulation of HSF1-mediated heat shock response; snRNP Assembly; ISG15 antiviral mechanism; HCMV Late Events; HCMV Early Events; Transcriptional regulation by small RNAs; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"28"	"0"	"327.0"	"277.6"	"355.9"	"325.4"	"355.1"	"307.1"	"376.1"	"426.6"	"946.5"	"2643.2"	"4591.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q2TAY7"	"WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2"	"17"	"7"	"15"	"7"	"513"	"57.5"	"7.18"	"2688.24"	"27.90"	"7"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf00400, Pf17814"	"55234"	"ENSG00000122692"	"SMU1"	"B4E3L0; hsa:55234; Q2TAY7; Q9BU59; Q9HA96; Q9NVD1"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"399.4"	"429.1"	"381.0"	"386.9"	"409.5"	"399.6"	"494.8"	"658.7"	"1182.8"	"2439.2"	"3312.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62753"	"40S ribosomal protein S6 OS=Homo sapiens OX=9606 GN=RPS6 PE=1 SV=1"	"22"	"9"	"17"	"9"	"249"	"28.7"	"10.84"	"3363.11"	"27.73"	"9"	"8"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01092"	"6194"	"ENSG00000137154"	"RPS6"	"hsa:6194; P08227; P10660; P62753; Q4VBY7; Q8N6Z7"	"IL-5 signaling pathway; Thyroid stimulating hormone (TSH) signaling pathway; Leptin signaling pathway; Follicle stimulating hormone (FSH) signaling pathway; Prolactin signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; Interleukin-11 signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Kit receptor signaling pathway; MECP2 and associated Rett syndrome; VEGFA-VEGFR2 signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Thermogenesis; Translation inhibitors in chronically activated PDGFRA cells; Gastrin signaling pathway; Head and neck squamous cell carcinoma; Thyroid hormones production and peripheral downstream signaling effects; Cytoplasmic ribosomal proteins; EGFR tyrosine kinase inhibitor resistance; IL-2 signaling pathway; Pleural mesothelioma; 2q37 copy number variation syndrome; A network map of Macrophage-stimulating protein (MSP) signaling; Interferon type I signaling pathways"	"Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; mTORC1-mediated signalling; rRNA modification in the nucleus and cytosol; SARS-CoV-2 modulates host translation machinery; Nuclear events stimulated by ALK signaling in cancer; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"47"	"0"	"1591.3"	"1251.9"	"1528.5"	"1409.9"	"1528.9"	"1629.7"	"1876.2"	"2023.4"	"2754.5"	"4034.6"	"6209.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99613"	"Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1"	"9"	"7"	"16"	"7"	"913"	"105.3"	"5.68"	"3204.40"	"27.72"	"6"	"6"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf01399, Pf05470"	"8663"	"ENSG00000184110"	"EIF3C"	"A8K7Z0; B2RXG3; B4E1D5; H3BRV0; hsa:8663; O00215; Q99613; Q9BW98"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex"	"8"	"0"	"375.9"	"382.6"	"421.8"	"384.1"	"382.1"	"379.2"	"477.9"	"606.8"	"967.6"	"1653.3"	"3538.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q00535"	"Cyclin-dependent-like kinase 5 OS=Homo sapiens OX=9606 GN=CDK5 PE=1 SV=3"	"25"	"6"	"14"	"6"	"292"	"33.3"	"7.66"	"2046.44"	"27.64"	"4"	"6"	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;kinase activity;other molecular function"	"Pf00069"	"1020"	"ENSG00000164885"	"CDK5"	"A1XKG3; hsa:1020; Q00535"	"miRNA regulation of DNA damage response; Nicotine effect on dopaminergic neurons; Alzheimer's disease and miRNA effects; Brain-derived neurotrophic factor (BDNF) signaling pathway; ATM signaling in development and disease ; Alzheimer's disease; Neurogenesis regulation in the olfactory epithelium; DNA damage response"	"NPAS4 regulates expression of target genes; NGF-stimulated transcription; Regulation of TP53 Activity through Phosphorylation; Factors involved in megakaryocyte development and platelet production; CRMPs in Sema3A signaling; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models; DARPP-32 events; Activated NTRK2 signals through CDK5"	"16"	"0"	"125.8"	"126.9"	"143.8"	"135.9"	"181.6"	"262.4"	"407.5"	"743.3"	"1432.8"	"3008.5"	"5209.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14160"	"Protein scribble homolog OS=Homo sapiens OX=9606 GN=SCRIB PE=1 SV=4"	"6"	"8"	"13"	"8"	"1630"	"174.8"	"5.07"	"1881.36"	"27.62"	"5"	"8"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"559.8"	"554.6"	"599.7"	"548.5"	"624.8"	"578.7"	"631.4"	"729.2"	"1219.6"	"2282.2"	"3867.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P43490"	"Nicotinamide phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=NAMPT PE=1 SV=1"	"18"	"8"	"16"	"8"	"491"	"55.5"	"7.15"	"2315.58"	"27.55"	"6"	"8"	"cell-cell signaling;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf04095, Pf18127"	"10135"	"ENSG00000105835"	"NAMPT"	"A4D0Q9; A4D0R0; hsa:10135; P43490; Q3KQV0; Q8WW95"	"Adipogenesis; NAD metabolism, sirtuins and aging; NAD+ metabolism; NAD+ biosynthetic pathways; Caloric restriction and aging; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence"	"NPAS4 regulates expression of target genes; BMAL1:CLOCK,NPAS2 activates circadian gene expression; Nicotinamide salvaging"	"9"	"0"	"620.7"	"645.9"	"587.5"	"524.4"	"649.6"	"600.1"	"761.3"	"1063.3"	"2386.1"	"4212.3"	"5171.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P45973"	"Chromobox protein homolog 5 OS=Homo sapiens OX=9606 GN=CBX5 PE=1 SV=1"	"38"	"6"	"15"	"6"	"191"	"22.2"	"5.86"	"3061.53"	"27.46"	"6"	"5"	"cell organization and biogenesis;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00385, Pf01393"	"23468"	"ENSG00000094916"	"CBX5"	"B2R8T9; hsa:23468; P45973"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; 22q11.2 copy number variation syndrome"	"SUMOylation of chromatin organization proteins; Transcriptional Regulation by E2F6; Factors involved in megakaryocyte development and platelet production"	"5"	"0"	"195.5"	"188.9"	"205.4"	"188.6"	"199.5"	"200.4"	"243.1"	"344.4"	"1387.1"	"3061.5"	"4856.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQ04"	"RNA-binding protein 4B OS=Homo sapiens OX=9606 GN=RBM4B PE=1 SV=1"	"24"	"7"	"13"	"7"	"359"	"40.1"	"6.74"	"2196.79"	"27.27"	"6"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00076, Pf00098"	"83759"	"ENSG00000173914"	"RBM4B"	"B3KT83; hsa:83759; Q9BQ04"	""	""	"0"	"0"	"440.7"	"493.3"	"458.2"	"386.9"	"475.4"	"417.5"	"534.9"	"715.8"	"1141.3"	"2007.1"	"3034.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y450"	"HBS1-like protein OS=Homo sapiens OX=9606 GN=HBS1L PE=1 SV=1"	"15"	"9"	"16"	"9"	"684"	"75.4"	"6.61"	"3009.08"	"27.26"	"8"	"8"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03143, Pf03144, Pf08938"	"10767"	"ENSG00000112339"	"HBS1L"	"B7Z365; hsa:10767; Q4VX89; Q4VX90; Q5T7G3; Q8NDW9; Q9UPW3; Q9Y450"	""	"mRNA decay by 3' to 5' exoribonuclease"	"1"	"0"	"422.9"	"352.4"	"435.2"	"392.8"	"447.3"	"463.1"	"701.3"	"1766.0"	"2296.4"	"1712.0"	"1428.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P28340"	"DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2"	"9"	"7"	"12"	"7"	"1107"	"123.6"	"7.03"	"2756.34"	"27.17"	"6"	"6"	"DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00136, Pf03104, Pf14260"	"5424"	"ENSG00000062822"	"POLD1"	"hsa:5424; P28340; Q8NER3; Q96H98"	"Homologous recombination; Pyrimidine metabolism; DNA replication; Base excision repair; Nucleotide excision repair; DNA repair pathways, full network; Progeria-associated lipodystrophy; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Cytosolic iron-sulfur cluster assembly; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Polymerase switching on the C-strand of the telomere; Polymerase switching; Removal of the Flap Intermediate; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"27"	"0"	"284.5"	"269.5"	"365.1"	"352.5"	"327.7"	"290.0"	"393.5"	"454.1"	"847.4"	"1672.3"	"2687.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UNS2"	"COP9 signalosome complex subunit 3 OS=Homo sapiens OX=9606 GN=COPS3 PE=1 SV=3"	"16"	"4"	"14"	"4"	"423"	"47.8"	"6.65"	"2999.73"	"27.13"	"4"	"4"	"protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf01399"	"8533"	"ENSG00000141030"	"COPS3"	"B2R683; B4DY81; hsa:8533; O43191; Q7LDR6; Q9UNS2"	"Ciliary landscape; Smith-Magenis and Potocki-Lupski syndrome copy number variation"	"Neddylation; DNA Damage Recognition in GG-NER; Cargo recognition for clathrin-mediated endocytosis; Formation of TC-NER Pre-Incision Complex"	"6"	"0"	"116.6"	"114.3"	"136.1"	"117.6"	"134.6"	"153.1"	"213.7"	"319.7"	"573.1"	"1259.3"	"2225.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y6I3"	"Epsin-1 OS=Homo sapiens OX=9606 GN=EPN1 PE=1 SV=2"	"18"	"7"	"12"	"7"	"576"	"60.3"	"4.83"	"1726.11"	"27.13"	"5"	"7"	"transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle"	"other molecular function"	"Pf01417, Pf02809"	"29924"	"ENSG00000063245"	"EPN1"	"hsa:29924; Q86ST3; Q9HA18; Q9Y6I3"	"VEGFA-VEGFR2 signaling; EGF/EGFR signaling pathway"	"Cargo recognition for clathrin-mediated endocytosis; EGFR downregulation"	"5"	"0"	"56.5"	"75.8"	"135.8"	"196.7"	"348.3"	"504.9"	"703.1"	"913.7"	"1097.2"	"1431.5"	"1664.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5SW79"	"Centrosomal protein of 170 kDa OS=Homo sapiens OX=9606 GN=CEP170 PE=1 SV=1"	"6"	"7"	"15"	"7"	"1584"	"175.2"	"7.11"	"2240.49"	"27.06"	"5"	"7"	""	"cytosol;cytoskeleton;other cell component"	""	"Pf00498, Pf15308"	"9859"	"ENSG00000143702; ENSG00000276725"	"CEP170"	"hsa:9859; O75058; Q5SW77; Q5SW78; Q5SW79; Q7LGA9; Q86W31; Q9UQ08; Q9UQ09"	"Ciliary landscape"	""	"1"	"0"	"488.5"	"380.0"	"577.0"	"487.7"	"533.9"	"524.2"	"578.2"	"665.4"	"905.3"	"1210.8"	"1597.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P16104"	"Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2"	"33"	"4"	"12"	"2"	"143"	"15.1"	"10.74"	"1792.57"	"26.95"	"2"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125, Pf16211"	"3014"	"ENSG00000188486"	"H2AX"	"hsa:3014; P16104; Q4ZGJ7; Q6IAS5"	"miRNA regulation of DNA damage response; miRNAs involved in DNA damage response; Proteasome degradation; ATM signaling in development and disease ; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; DNA repair pathways, full network; 5q35 copy number variation; DNA damage response"	"Amyloid fiber formation; Meiotic synapsis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Transcriptional regulation by small RNAs; Deposition of new CENPA-containing nucleosomes at the centromere; B-WICH complex positively regulates rRNA expression; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Formation of the beta-catenin:TCF transactivating complex; Oxidative Stress Induced Senescence; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Pre-NOTCH Transcription and Translation; Senescence-Associated Secretory Phenotype (SASP); RMTs methylate histone arginines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; RNA Polymerase I Promoter Escape; Meiotic recombination; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Packaging Of Telomere Ends; Condensation of Prophase Chromosomes; DNA Damage/Telomere Stress Induced Senescence; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; Nonhomologous End-Joining (NHEJ); RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis"	"46"	"2"	"652.9"	"650.0"	"707.8"	"585.9"	"581.3"	"639.1"	"781.1"	"927.3"	"1308.3"	"2016.2"	"2881.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96FV9"	"THO complex subunit 1 OS=Homo sapiens OX=9606 GN=THOC1 PE=1 SV=1"	"13"	"6"	"11"	"6"	"657"	"75.6"	"4.98"	"1901.11"	"26.92"	"4"	"6"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;transport;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00531, Pf11957"	"9984"	"ENSG00000079134"	"THOC1"	"B2RBP6; hsa:9984; Q15219; Q64I72; Q64I73; Q96FV9"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"3"	"0"	"277.4"	"287.4"	"296.2"	"239.4"	"259.2"	"279.9"	"348.7"	"457.7"	"617.3"	"1079.4"	"1725.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00148"	"ATP-dependent RNA helicase DDX39A OS=Homo sapiens OX=9606 GN=DDX39A PE=1 SV=2"	"14"	"6"	"15"	"1"	"427"	"49.1"	"5.68"	"2519.28"	"26.91"	"5"	"6"	"RNA metabolism OR transcription;other metabolic processes;transport"	"nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271"	"10212"	"ENSG00000123136"	"DDX39A"	"B1Q2N1; hsa:10212; O00148; Q8N5M0; Q9BVP6; Q9H5W0"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"3"	"0"	"44.9"	"29.8"	"52.0"	"48.4"	"52.3"	"43.1"	"45.3"	"64.6"	"103.0"	"172.4"	"308.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3F4"	"Serine-threonine kinase receptor-associated protein OS=Homo sapiens OX=9606 GN=STRAP PE=1 SV=1"	"24"	"5"	"11"	"5"	"350"	"38.4"	"5.12"	"2461.89"	"26.87"	"4"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00400"	"11171"	"ENSG00000023734"	"STRAP"	"B2R5S5; B4DNJ6; hsa:11171; Q5TZT4; Q9NTK0; Q9UQC8; Q9Y3F4"	"Epithelial to mesenchymal transition in colorectal cancer"	"Downregulation of TGF-beta receptor signaling"	"2"	"0"	"408.4"	"367.6"	"422.5"	"355.3"	"405.9"	"440.1"	"508.4"	"711.6"	"969.6"	"1972.0"	"4089.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35658"	"Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2"	"4"	"7"	"14"	"7"	"2090"	"213.5"	"7.47"	"2829.25"	"26.85"	"7"	"7"	"cell cycle OR cell proliferation;other metabolic processes;transport;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf18617"	"8021"	"ENSG00000126883"	"NUP214"	"A6NFQ0; hsa:8021; P35658; Q15010; Q3KQZ0; Q5JUP7; Q75R47; Q86XD3"	""	"Rev-mediated nuclear export of HIV RNA; Nuclear import of Rev protein; HCMV Late Events; HCMV Early Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; HuR (ELAVL1) binds and stabilizes mRNA"	"29"	"0"	"868.4"	"635.6"	"852.6"	"754.0"	"901.1"	"982.4"	"993.0"	"1064.7"	"1627.8"	"3121.2"	"4637.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P15880"	"40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2"	"31"	"8"	"17"	"8"	"293"	"31.3"	"10.24"	"3624.85"	"26.61"	"8"	"7"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00333, Pf03719"	"6187"	"ENSG00000140988"	"RPS2"	"B2R5G0; D3DU82; hsa:6187; P15880; Q3MIB1"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; RMTs methylate histone arginines; rRNA modification in the nucleus and cytosol; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Protein methylation; Peptide chain elongation; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"22"	"0"	"659.7"	"826.8"	"738.0"	"593.4"	"643.1"	"627.1"	"886.9"	"1394.7"	"2436.1"	"4921.8"	"7288.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13148"	"TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1"	"22"	"7"	"11"	"7"	"414"	"44.7"	"6.19"	"2236.98"	"26.59"	"3"	"6"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf18694"	"23435"	"ENSG00000120948"	"TARDBP"	"A4GUK4; A4GUK5; A4GUK6; B2R629; B4DJ45; E2PU12; hsa:23435; Q13148; Q53H27; Q6FI92; Q96DJ0"	"MECP2 and associated Rett syndrome"	""	"1"	"0"	"770.7"	"662.1"	"774.1"	"687.2"	"723.1"	"708.4"	"939.2"	"1226.6"	"1632.6"	"2669.9"	"4553.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P12268"	"Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2"	"20"	"8"	"12"	"8"	"514"	"55.8"	"6.90"	"3011.56"	"26.56"	"6"	"6"	"cell cycle OR cell proliferation;other metabolic processes;developmental processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00478, Pf00571"	"3615"	"ENSG00000178035"	"IMPDH2"	"hsa:3615; P12268; Q6LEF3"	"Rett syndrome causing genes"	"Potential therapeutics for SARS; Neutrophil degranulation; Purine ribonucleoside monophosphate biosynthesis; Azathioprine ADME"	"5"	"0"	"368.5"	"420.8"	"339.2"	"328.4"	"347.2"	"295.0"	"384.5"	"534.4"	"1139.7"	"3065.2"	"5857.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05387"	"60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1"	"75"	"5"	"12"	"4"	"115"	"11.7"	"4.54"	"2492.31"	"26.55"	"4"	"4"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf00428"	"6181"	"ENSG00000177600"	"RPLP2"	"hsa:6181; P05387; Q6FG96"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins; Opioid receptor pathways"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"16"	"1"	"211.7"	"311.3"	"262.4"	"208.5"	"289.1"	"268.2"	"335.4"	"593.6"	"1220.6"	"1906.5"	"3024.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14936"	"Peripheral plasma membrane protein CASK OS=Homo sapiens OX=9606 GN=CASK PE=1 SV=3"	"8"	"7"	"14"	"7"	"926"	"105.1"	"6.43"	"2705.32"	"26.50"	"7"	"7"	"cell adhesion;protein metabolism;other metabolic processes;transport;other biological processes"	"extracellular matrix;plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;kinase activity;other molecular function"	"Pf00018, Pf00069, Pf00595, Pf00625, Pf02828"	"8573"	"ENSG00000147044"	"CASK"	"A6NES1; B7ZKY0; hsa:8573; O14936; O43215; Q17RI4; Q59HA0; Q5VT16; Q5VT17; Q5VT18; Q5VT19; Q66T42; Q9BYH6; Q9NYB2; Q9NYB3"	"Parkin-ubiquitin proteasomal system pathway; Splicing factor NOVA regulated synaptic proteins"	"Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Assembly and cell surface presentation of NMDA receptors; Nephrin family interactions; Neurexins and neuroligins; Dopamine Neurotransmitter Release Cycle; Syndecan interactions"	"9"	"0"	"323.7"	"294.5"	"368.0"	"320.0"	"381.8"	"290.4"	"409.3"	"522.3"	"1755.0"	"3640.5"	"4494.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05141"	"ADP/ATP translocase 2 OS=Homo sapiens OX=9606 GN=SLC25A5 PE=1 SV=7"	"30"	"9"	"18"	"4"	"298"	"32.8"	"9.69"	"3993.80"	"26.49"	"9"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytoskeleton;mitochondrion"	"transporter activity;other molecular function"	"Pf00153"	"292"	"ENSG00000005022"	"SLC25A5"	"B2RCV1; hsa:292; O43350; P05141"	"Electron transport chain: OXPHOS system in mitochondria; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane; Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization"	"5"	"4"	"638.3"	"648.5"	"737.8"	"696.9"	"683.2"	"625.2"	"826.7"	"1048.7"	"1804.6"	"3345.9"	"4512.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96CT7"	"Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1"	"39"	"7"	"13"	"7"	"223"	"25.8"	"9.54"	"2371.11"	"26.46"	"6"	"7"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf06244"	"115098"	"ENSG00000007080"	"CCDC124"	"hsa:115098; Q96CT7"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"828.8"	"610.4"	"806.1"	"745.1"	"790.0"	"910.1"	"1020.5"	"1051.5"	"1626.5"	"1918.8"	"1888.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55010"	"Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2"	"18"	"7"	"9"	"7"	"431"	"49.2"	"5.58"	"310.03"	"26.41"	"1"	"7"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf01873, Pf02020"	"1983"	"ENSG00000100664"	"EIF5"	"hsa:1983; P55010; Q53XB3; Q9H5N2; Q9UG48"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"4"	"0"	"114.8"	"99.5"	"140.3"	"120.2"	"133.5"	"130.3"	"181.5"	"236.2"	"556.7"	"3808.9"	"8353.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WXF1"	"Paraspeckle component 1 OS=Homo sapiens OX=9606 GN=PSPC1 PE=1 SV=1"	"14"	"6"	"12"	"6"	"523"	"58.7"	"6.67"	"1487.85"	"26.31"	"5"	"6"	"stress response;other biological processes"	"nucleus;other cell component"	""	"Pf00076, Pf08075"	"55269"	"ENSG00000121390"	"PSPC1"	"hsa:55269; Q5JTQ3; Q8NCZ9; Q8WXE8; Q8WXF1; Q9NV36"	""	""	"0"	"0"	"718.8"	"650.9"	"663.7"	"593.7"	"677.4"	"689.8"	"756.6"	"856.7"	"1276.3"	"2156.3"	"3224.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9ULV4"	"Coronin-1C OS=Homo sapiens OX=9606 GN=CORO1C PE=1 SV=1"	"22"	"11"	"20"	"11"	"474"	"53.2"	"7.08"	"4467.28"	"26.21"	"11"	"7"	"cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400, Pf08953, Pf16300"	"23603"	"ENSG00000110880"	"CORO1C"	"A7MAP0; A7MAP1; B3KU12; hsa:23603; Q9NSK5; Q9ULV4"	""	""	"0"	"0"	"992.7"	"847.5"	"949.7"	"852.4"	"999.1"	"974.5"	"1195.7"	"1312.8"	"2198.4"	"4449.6"	"7380.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WYA6"	"Beta-catenin-like protein 1 OS=Homo sapiens OX=9606 GN=CTNNBL1 PE=1 SV=1"	"12"	"7"	"13"	"7"	"563"	"65.1"	"5.05"	"1991.76"	"26.13"	"5"	"7"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf08216"	"56259"	"ENSG00000132792"	"CTNNBL1"	"B4DE16; hsa:56259; Q0VAL9; Q0VAM0; Q53HI8; Q5JWZ2; Q5JWZ3; Q5JWZ7; Q5JWZ8; Q8N454; Q8NCL2; Q8TBD6; Q8WYA6; Q96KD2; Q9H7A5; Q9NQF9; Q9NTX0; Q9Y3M7"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"376.7"	"385.4"	"438.7"	"376.3"	"416.4"	"391.7"	"498.7"	"586.1"	"1637.3"	"5839.7"	"8112.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H910"	"Jupiter microtubule associated homolog 2 OS=Homo sapiens OX=9606 GN=JPT2 PE=1 SV=1"	"45"	"5"	"10"	"5"	"190"	"20.1"	"9.26"	"1680.13"	"26.08"	"3"	"5"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	""	"Pf17054"	"90861"	"ENSG00000206053"	"JPT2"	"B1AJY2; B4DLH4; hsa:90861; Q6EIC7; Q9H910"	""	""	"0"	"0"	"121.9"	"103.4"	"133.4"	"135.0"	"141.8"	"136.7"	"164.3"	"184.2"	"373.9"	"808.0"	"1107.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5VUJ6"	"Leucine-rich repeat and calponin homology domain-containing protein 2 OS=Homo sapiens OX=9606 GN=LRCH2 PE=1 SV=2"	"12"	"5"	"8"	"5"	"765"	"84.5"	"6.55"	"1593.85"	"26.05"	"3"	"5"	""	""	""	"Pf00307, Pf13855"	"57631"	"ENSG00000130224"	"LRCH2"	"F5H2T1; hsa:57631; Q08AD5; Q5VUJ6; Q9HA88; Q9P233"	""	""	"0"	"0"	"209.8"	"172.5"	"224.7"	"198.0"	"233.7"	"228.6"	"315.8"	"417.5"	"706.9"	"1099.4"	"1242.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95218"	"Zinc finger Ran-binding domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ZRANB2 PE=1 SV=2"	"17"	"4"	"12"	"4"	"330"	"37.4"	"10.01"	"3088.22"	"25.86"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00641"	"9406"	"ENSG00000132485"	"ZRANB2"	"D3DQ75; hsa:9406; O95218; Q53GS3; Q59F92; Q5VV33; Q5VV34; Q8IXN6; Q9UP63"	""	""	"0"	"0"	"801.7"	"568.9"	"771.6"	"750.7"	"824.6"	"844.7"	"929.0"	"936.4"	"1101.1"	"1557.3"	"2121.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30405"	"Peptidyl-prolyl cis-trans isomerase F, mitochondrial OS=Homo sapiens OX=9606 GN=PPIF PE=1 SV=1"	"36"	"6"	"14"	"5"	"207"	"22.0"	"9.38"	"1853.92"	"25.81"	"4"	"6"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"other membranes;mitochondrion;other cell component"	"other molecular function"	"Pf00160"	"10105"	"ENSG00000108179"	"PPIF"	"hsa:10105; P30405; Q2YDB7; Q5W131"	"Alzheimer's disease and miRNA effects; Alzheimer's disease"	""	"2"	"1"	"1224.3"	"1251.1"	"1369.8"	"1408.0"	"1373.9"	"1268.0"	"1616.2"	"1884.4"	"2365.1"	"4505.6"	"6134.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P47813"	"Eukaryotic translation initiation factor 1A, X-chromosomal OS=Homo sapiens OX=9606 GN=EIF1AX PE=1 SV=2"	"69"	"8"	"13"	"8"	"144"	"16.5"	"5.24"	"3149.87"	"25.81"	"7"	"6"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf01176"	"1964"	"ENSG00000173674"	"EIF1AX"	"B2R5U5; hsa:1964; P47813; Q0VGC2; Q5JPS5; Q5JPS6"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition"	"8"	"0"	"168.8"	"141.8"	"191.6"	"161.1"	"186.4"	"199.3"	"242.6"	"257.5"	"2819.8"	"10724.6"	"5151.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O76021"	"Ribosomal L1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RSL1D1 PE=1 SV=3"	"21"	"8"	"15"	"7"	"490"	"54.9"	"10.13"	"3238.06"	"25.77"	"8"	"7"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00687"	"26156"	"ENSG00000171490"	"RSL1D1"	"B4DJ58; D3DUG7; hsa:26156; O76021; Q2M1T7; Q6PL22; Q8IWS7; Q8WUZ1; Q9HDA9; Q9Y3Z9"	""	""	"0"	"1"	"658.6"	"465.1"	"667.0"	"556.1"	"638.7"	"669.5"	"806.8"	"873.4"	"1607.8"	"2497.1"	"3597.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19388"	"DNA-directed RNA polymerases I, II, and III subunit RPABC1 OS=Homo sapiens OX=9606 GN=POLR2E PE=1 SV=4"	"32"	"5"	"11"	"5"	"210"	"24.5"	"5.95"	"1903.31"	"25.71"	"4"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01191, Pf03871"	"5434"	"ENSG00000099817"	"POLR2E"	"B2R6L4; D6W5Y1; hsa:5434; O43380; P19388; Q6PIH5; Q9BT06"	"Pyrimidine metabolism; Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"mRNA Splicing - Major Pathway; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; B-WICH complex positively regulates rRNA expression; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"57"	"0"	"285.9"	"347.5"	"314.1"	"292.5"	"328.8"	"341.7"	"389.1"	"551.4"	"1273.9"	"2498.9"	"3667.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94973"	"AP-2 complex subunit alpha-2 OS=Homo sapiens OX=9606 GN=AP2A2 PE=1 SV=2"	"9"	"7"	"15"	"4"	"939"	"103.9"	"6.96"	"2620.75"	"25.69"	"6"	"6"	"transport"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01602, Pf02296, Pf02883"	"161"	"ENSG00000183020"	"AP2A2"	"hsa:161; O75403; O94973; Q53ET1; Q96SI8"	"Synaptic vesicle pathway; GABA receptor signaling; mBDNF and proBDNF regulation of GABA neurotransmission"	"MHC class II antigen presentation; Potential therapeutics for SARS; Recycling pathway of L1; Neutrophil degranulation; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; LDL clearance; Nef Mediated CD4 Down-regulation; Retrograde neurotrophin signalling; Nef Mediated CD8 Down-regulation; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; VLDLR internalisation and degradation"	"17"	"0"	"58.9"	"46.4"	"75.2"	"56.2"	"75.2"	"113.2"	"272.6"	"750.1"	"1014.7"	"843.7"	"723.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P27816"	"Microtubule-associated protein 4 OS=Homo sapiens OX=9606 GN=MAP4 PE=1 SV=3"	"9"	"9"	"17"	"9"	"1152"	"120.9"	"5.43"	"4239.50"	"25.66"	"9"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00418"	"4134"	"ENSG00000047849"	"MAP4"	"hsa:4134; P27816; Q13082; Q59FT2; Q68D74; Q6ZUW9; Q86V26; Q96A76; Q96NS9"	"Splicing factor NOVA regulated synaptic proteins; 2q37 copy number variation syndrome"	""	"2"	"0"	"1249.7"	"1037.4"	"1176.9"	"1061.5"	"1196.8"	"1166.1"	"1410.5"	"1435.5"	"1998.9"	"3056.0"	"4661.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15143"	"Actin-related protein 2/3 complex subunit 1B OS=Homo sapiens OX=9606 GN=ARPC1B PE=1 SV=3"	"24"	"8"	"14"	"7"	"372"	"40.9"	"8.35"	"2242.07"	"25.65"	"5"	"7"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400"	"10095"	"ENSG00000130429"	"ARPC1B"	"hsa:10095; O15143; Q9BU00"	"Pathogenic Escherichia coli infection; Microglia pathogen phagocytosis pathway"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; EPHB-mediated forward signaling"	"6"	"1"	"585.7"	"633.3"	"616.7"	"516.5"	"561.0"	"542.2"	"705.6"	"876.3"	"2828.4"	"4873.5"	"7813.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15022"	"Polycomb protein SUZ12 OS=Homo sapiens OX=9606 GN=SUZ12 PE=1 SV=3"	"8"	"4"	"8"	"4"	"739"	"83.0"	"8.81"	"1721.59"	"25.64"	"2"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf09733"	"23512"	"ENSG00000178691"	"SUZ12"	"hsa:23512; Q15022; Q96BD9"	"Interactome of polycomb repressive complex 2 (PRC2) ; Tumor suppressor activity of SMARCB1; Epithelial to mesenchymal transition in colorectal cancer; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; Pleural mesothelioma"	"SUMOylation of chromatin organization proteins; Regulation of PTEN gene transcription; HCMV Early Events; Oxidative Stress Induced Senescence; Transcriptional Regulation by E2F6; Activation of anterior HOX genes in hindbrain development during early embryogenesis; PKMTs methylate histone lysines; PRC2 methylates histones and DNA; Defective pyroptosis"	"14"	"0"	"33.7"	"35.9"	"42.5"	"37.7"	"39.6"	"33.3"	"48.2"	"68.1"	"151.1"	"359.5"	"482.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94832"	"Unconventional myosin-Id OS=Homo sapiens OX=9606 GN=MYO1D PE=1 SV=2"	"8"	"7"	"14"	"7"	"1006"	"116.1"	"9.39"	"2511.10"	"25.61"	"7"	"7"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00063, Pf00612, Pf06017"	"4642"	"ENSG00000176658"	"MYO1D"	"A6H8V3; hsa:4642; O94832; Q8NHP9"	""	""	"0"	"0"	"260.6"	"271.1"	"293.5"	"248.6"	"286.3"	"286.2"	"362.4"	"564.2"	"1278.7"	"2716.7"	"4125.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05388"	"60S acidic ribosomal protein P0 OS=Homo sapiens OX=9606 GN=RPLP0 PE=1 SV=1"	"27"	"7"	"14"	"7"	"317"	"34.3"	"5.97"	"2876.12"	"25.58"	"7"	"7"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00428, Pf00466, Pf17777"	"6175"	"ENSG00000089157"	"RPLP0"	"hsa:6175; P05388; Q3B7A4; Q9BVK4"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"15"	"0"	"290.2"	"328.3"	"343.2"	"267.7"	"319.7"	"314.4"	"380.5"	"583.3"	"1129.1"	"2200.7"	"3886.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"E9PAV3"	"Nascent polypeptide-associated complex subunit alpha, muscle-specific form OS=Homo sapiens OX=9606 GN=NACA PE=1 SV=1"	"4"	"5"	"9"	"5"	"2078"	"205.3"	"9.58"	"1205.46"	"25.48"	"2"	"5"	"transport"	"translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01849, Pf19026"	""	"ENSG00000196531"	"NACA"	"E9PAV3"	""	""	"0"	"0"	"105.5"	"109.0"	"138.6"	"112.6"	"118.5"	"117.3"	"151.8"	"234.7"	"480.1"	"1530.2"	"3510.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49454"	"Centromere protein F OS=Homo sapiens OX=9606 GN=CENPF PE=1 SV=3"	"3"	"9"	"17"	"8"	"3114"	"357.3"	"5.10"	"3628.69"	"25.44"	"9"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf10473, Pf10481, Pf10490"	"1063"	"ENSG00000117724"	"CENPF"	"hsa:1063; P49454; Q13171; Q13246; Q5VVM7"	"Gastric cancer network 1; Ciliopathies"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Polo-like kinase mediated events"	"9"	"0"	"269.9"	"211.9"	"310.0"	"210.0"	"273.7"	"289.1"	"323.1"	"396.9"	"608.5"	"1042.7"	"1426.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62495"	"Eukaryotic peptide chain release factor subunit 1 OS=Homo sapiens OX=9606 GN=ETF1 PE=1 SV=3"	"22"	"7"	"15"	"7"	"437"	"49.0"	"5.71"	"2447.69"	"25.41"	"6"	"7"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"enzyme regulator activity;translation activity;nucleic acid binding activity;other molecular function"	"Pf03463, Pf03464, Pf03465"	"2107"	"ENSG00000120705"	"ETF1"	"B2R6B4; D3DQC1; hsa:2107; P46055; P62495; Q5M7Z7; Q96CG1"	"Translation factors"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"5"	"0"	"261.8"	"274.5"	"288.3"	"230.1"	"295.7"	"303.3"	"356.5"	"507.5"	"1286.7"	"2368.3"	"2659.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBL3"	"Set1/Ash2 histone methyltransferase complex subunit ASH2 OS=Homo sapiens OX=9606 GN=ASH2L PE=1 SV=1"	"11"	"6"	"10"	"6"	"628"	"68.7"	"5.69"	"1896.15"	"25.32"	"4"	"6"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00622"	"9070"	"ENSG00000129691"	"ASH2L"	"A8K7C3; D3DSW9; hsa:9070; O60659; O60660; Q96B62; Q9UBL3"	"Kleefstra syndrome"	"Deactivation of the beta-catenin transactivating complex; Formation of the beta-catenin:TCF transactivating complex; Activation of anterior HOX genes in hindbrain development during early embryogenesis; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Formation of WDR5-containing histone-modifying complexes; PKMTs methylate histone lysines"	"7"	"0"	"205.9"	"177.3"	"199.9"	"171.6"	"209.8"	"218.3"	"253.4"	"348.0"	"1011.5"	"2708.1"	"4716.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P53621"	"Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2"	"8"	"9"	"16"	"9"	"1224"	"138.3"	"7.66"	"2693.83"	"25.24"	"7"	"7"	"transport;signal transduction"	"non-structural extracellular;other membranes;cytosol;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00400, Pf04053, Pf06957, Pf12894"	"1314"	"ENSG00000122218"	"COPA"	"hsa:1314; P53621; Q5T201; Q8IXZ9"	""	"COPI-mediated anterograde transport; COPI-dependent Golgi-to-ER retrograde traffic"	"2"	"0"	"794.4"	"696.9"	"871.2"	"721.1"	"829.3"	"688.8"	"901.3"	"1138.4"	"1778.5"	"3538.8"	"5775.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14910"	"Protein lin-7 homolog A OS=Homo sapiens OX=9606 GN=LIN7A PE=1 SV=2"	"31"	"9"	"16"	"5"	"233"	"26.0"	"8.72"	"2675.58"	"25.23"	"8"	"8"	"cell-cell signaling;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00595, Pf02828"	"8825"	"ENSG00000111052"	"LIN7A"	"A4FTY3; hsa:8825; O14910; Q147W1; Q6LES3; Q7LDS4"	""	"Assembly and cell surface presentation of NMDA receptors; Neurexins and neuroligins; Dopamine Neurotransmitter Release Cycle"	"3"	"4"	"580.7"	"541.8"	"664.0"	"543.1"	"593.8"	"632.9"	"711.9"	"884.3"	"2735.3"	"5939.4"	"8058.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96CX2"	"BTB/POZ domain-containing protein KCTD12 OS=Homo sapiens OX=9606 GN=KCTD12 PE=1 SV=1"	"25"	"6"	"12"	"6"	"325"	"35.7"	"5.64"	"2534.78"	"25.22"	"6"	"6"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf02214"	"115207"	"ENSG00000178695"	"KCTD12"	"hsa:115207; Q96CX2"	""	""	"0"	"0"	"144.0"	"124.8"	"151.0"	"133.0"	"158.4"	"138.0"	"184.5"	"255.5"	"630.8"	"2125.2"	"3479.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06899"	"Histone H2B type 1-J OS=Homo sapiens OX=9606 GN=H2BC11 PE=1 SV=3"	"35"	"4"	"15"	"1"	"126"	"13.9"	"10.32"	"2972.77"	"25.01"	"4"	"4"	"cell organization and biogenesis;stress response;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125"	"8970"	"ENSG00000124635"	"H2BC11"	"B2R4J4; hsa:8970; O60816; P06899"	""	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; Meiotic recombination; DNA Damage/Telomere Stress Induced Senescence; Nonhomologous End-Joining (NHEJ); Amyloid fiber formation; Deposition of new CENPA-containing nucleosomes at the centromere; E3 ubiquitin ligases ubiquitinate target proteins; Meiotic synapsis; HCMV Late Events; Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; HCMV Early Events; Transcriptional regulation by small RNAs; B-WICH complex positively regulates rRNA expression; Formation of the beta-catenin:TCF transactivating complex; Oxidative Stress Induced Senescence; HDACs deacetylate histones; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Pre-NOTCH Transcription and Translation; Senescence-Associated Secretory Phenotype (SASP); RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; HATs acetylate histones; RNA Polymerase I Promoter Escape; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Packaging Of Telomere Ends; Condensation of Prophase Chromosomes; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis"	"43"	"0"	"130.7"	"228.1"	"59.6"	"61.0"	"85.7"	"86.5"	"145.0"	"275.1"	"406.5"	"774.9"	"1189.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UHD8"	"Septin-9 OS=Homo sapiens OX=9606 GN=SEPTIN9 PE=1 SV=2"	"16"	"7"	"12"	"7"	"586"	"65.4"	"8.97"	"2161.14"	"24.96"	"5"	"7"	"cell cycle OR cell proliferation;other biological processes"	"cytoskeleton;other cell component"	"other molecular function"	"Pf00735"	"10801"	"ENSG00000184640"	"SEPTIN9"	"A8K2V3; B3KPM0; B4DTL9; B4E0N2; B4E274; B7Z654; hsa:10801; Q96QF3; Q96QF4; Q96QF5; Q9HA04; Q9UG40; Q9UHD8; Q9Y5W4"	""	""	"0"	"0"	"336.5"	"314.2"	"361.6"	"311.1"	"377.4"	"368.6"	"434.3"	"510.8"	"1075.2"	"1725.1"	"2250.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WW12"	"PEST proteolytic signal-containing nuclear protein OS=Homo sapiens OX=9606 GN=PCNP PE=1 SV=2"	"38"	"5"	"10"	"5"	"178"	"18.9"	"7.49"	"2582.24"	"24.96"	"5"	"5"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes"	"nucleus"	""	"Pf15473"	"57092"	"ENSG00000081154"	"PCNP"	"B2RBE7; D3DN52; hsa:57092; Q53GF3; Q6AI44; Q8WW12; Q96CU3; Q9NS81"	""	""	"0"	"0"	"492.9"	"408.6"	"533.1"	"486.9"	"517.7"	"516.5"	"561.0"	"574.5"	"827.0"	"2632.1"	"5566.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30153"	"Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4"	"15"	"8"	"14"	"8"	"589"	"65.3"	"5.11"	"2986.58"	"24.94"	"7"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02985"	"5518"	"ENSG00000105568"	"PPP2R1A"	"hsa:5518; P30153; Q13773; Q6ICQ3; Q96DH3"	"Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Wnt signaling pathway and pluripotency; PI3K-Akt signaling pathway; 16p11.2 proximal deletion syndrome; Glycogen synthesis and degradation; Cohesin complex - Cornelia de Lange syndrome"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Regulation of TP53 Degradation; RAF activation; Negative regulation of MAPK pathway; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Cyclin D associated events in G1; Disassembly of the destruction complex and recruitment of AXIN to the membrane; Cyclin A/B1/B2 associated events during G2/M transition; Beta-catenin phosphorylation cascade; Signaling by GSK3beta mutants; CTNNB1 S33 mutants aren't phosphorylated; CTNNB1 S37 mutants aren't phosphorylated; CTNNB1 S45 mutants aren't phosphorylated; CTNNB1 T41 mutants aren't phosphorylated; APC truncation mutants have impaired AXIN binding; AXIN missense mutants destabilize the destruction complex; Truncations of AMER1 destabilize the destruction complex; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Spry regulation of FGF signaling; MASTL Facilitates Mitotic Progression; Regulation of glycolysis by fructose 2,6-bisphosphate metabolism; Initiation of Nuclear Envelope (NE) Reformation; Platelet sensitization by LDL; CTLA4 inhibitory signaling; Inhibition of replication initiation of damaged DNA by RB1/E2F1; DARPP-32 events; PP2A-mediated dephosphorylation of key metabolic factors; ERKs are inactivated"	"49"	"0"	"342.9"	"314.6"	"419.3"	"331.6"	"364.4"	"325.7"	"444.3"	"621.0"	"1106.1"	"2183.1"	"3311.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14562"	"ATP-dependent RNA helicase DHX8 OS=Homo sapiens OX=9606 GN=DHX8 PE=1 SV=1"	"7"	"7"	"14"	"6"	"1220"	"139.2"	"8.32"	"2520.17"	"24.91"	"7"	"7"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf00271, Pf00575, Pf04408, Pf07717"	"1659"	"ENSG00000067596"	"DHX8"	"hsa:1659; Q14562"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"1"	"211.7"	"167.4"	"234.2"	"209.5"	"240.9"	"211.0"	"275.0"	"353.8"	"642.3"	"1401.9"	"2202.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BPW8"	"Protein NipSnap homolog 1 OS=Homo sapiens OX=9606 GN=NIPSNAP1 PE=1 SV=1"	"24"	"6"	"13"	"4"	"284"	"33.3"	"9.31"	"2397.13"	"24.91"	"5"	"6"	"other biological processes"	"plasma membrane;other membranes;mitochondrion"	"other molecular function"	"Pf07978"	"8508"	"ENSG00000184117"	"NIPSNAP1"	"B2RAY3; hsa:8508; O43800; Q9BPW8"	""	""	"0"	"2"	"645.1"	"620.2"	"633.4"	"571.3"	"609.3"	"612.3"	"753.1"	"860.5"	"1195.7"	"1811.1"	"2261.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92614"	"Unconventional myosin-XVIIIa OS=Homo sapiens OX=9606 GN=MYO18A PE=1 SV=3"	"4"	"6"	"13"	"6"	"2054"	"233.0"	"6.30"	"3371.51"	"24.90"	"6"	"5"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00063, Pf01576, Pf17820"	"399687"	"ENSG00000196535"	"MYO18A"	"hsa:399687; Q5H9U3; Q5QD01; Q5W9F9; Q5W9G1; Q8IXP8; Q92614"	""	"Signaling by cytosolic FGFR1 fusion mutants; Signaling by FGFR1 in disease; Signaling by FLT3 fusion proteins"	"3"	"0"	"126.1"	"125.9"	"133.8"	"111.6"	"131.4"	"129.5"	"174.7"	"210.8"	"279.8"	"567.6"	"745.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62937"	"Peptidyl-prolyl cis-trans isomerase A OS=Homo sapiens OX=9606 GN=PPIA PE=1 SV=2"	"36"	"7"	"12"	"7"	"165"	"18.0"	"7.81"	"1661.77"	"24.89"	"5"	"6"	"cell adhesion;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00160"	"5478"	"ENSG00000196262"	"PPIA"	"A8K220; hsa:5478; P05092; P62937; Q3KQW3; Q567Q0; Q6IBU5; Q96IX3; Q9BRU4; Q9BTY9; Q9UC61"	"Prolactin signaling pathway"	"Neutrophil degranulation; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Budding and maturation of HIV virion; Platelet degranulation ; Basigin interactions; SARS-CoV-1 activates/modulates innate immune responses; Integration of provirus; APOBEC3G mediated resistance to HIV-1 infection; Calcineurin activates NFAT; Binding and entry of HIV virion; Assembly Of The HIV Virion; Uncoating of the HIV Virion; Minus-strand DNA synthesis; Plus-strand DNA synthesis"	"16"	"0"	"333.0"	"500.5"	"460.3"	"453.0"	"344.4"	"333.5"	"478.0"	"693.5"	"1004.9"	"1763.6"	"6845.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60814"	"Histone H2B type 1-K OS=Homo sapiens OX=9606 GN=H2BC12 PE=1 SV=3"	"36"	"5"	"16"	"2"	"126"	"13.9"	"10.32"	"3515.54"	"24.88"	"5"	"4"	"stress response;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125"	"85236"	"ENSG00000197903"	"H2BC12"	"A8K7P7; hsa:85236; O60814; Q2VPI7"	""	"Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Formation of the beta-catenin:TCF transactivating complex; E3 ubiquitin ligases ubiquitinate target proteins; Amyloid fiber formation; Meiotic synapsis; HCMV Late Events; HCMV Early Events; Transcriptional regulation by small RNAs; Deposition of new CENPA-containing nucleosomes at the centromere; B-WICH complex positively regulates rRNA expression; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Oxidative Stress Induced Senescence; HDACs deacetylate histones; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Pre-NOTCH Transcription and Translation; Senescence-Associated Secretory Phenotype (SASP); RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; HATs acetylate histones; RNA Polymerase I Promoter Escape; Meiotic recombination; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Packaging Of Telomere Ends; Condensation of Prophase Chromosomes; DNA Damage/Telomere Stress Induced Senescence; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; Nonhomologous End-Joining (NHEJ); RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis"	"43"	"6"	"728.4"	"1475.5"	"544.3"	"469.8"	"600.6"	"611.5"	"874.2"	"1346.8"	"1787.1"	"3049.8"	"4026.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05114"	"Non-histone chromosomal protein HMG-14 OS=Homo sapiens OX=9606 GN=HMGN1 PE=1 SV=3"	"55"	"6"	"10"	"6"	"100"	"10.7"	"9.60"	"1056.64"	"24.81"	"3"	"6"	"cell organization and biogenesis;DNA metabolism;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01101"	"3150"	"ENSG00000205581"	"HMGN1"	"hsa:3150; P05114; Q3KQR8"	"ATM signaling in development and disease ; p38 MAPK signaling pathway; Pleural mesothelioma; Nucleotide excision repair in xeroderma pigmentosum"	"Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	"8"	"0"	"593.9"	"374.2"	"574.5"	"511.6"	"545.7"	"598.8"	"684.0"	"638.3"	"1146.5"	"992.8"	"655.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NVM6"	"DnaJ homolog subfamily C member 17 OS=Homo sapiens OX=9606 GN=DNAJC17 PE=1 SV=1"	"28"	"6"	"12"	"6"	"304"	"34.7"	"8.53"	"2256.09"	"24.79"	"5"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf00226"	"55192"	"ENSG00000104129"	"DNAJC17"	"hsa:55192; Q9NVM6"	""	""	"0"	"0"	"76.3"	"70.2"	"104.9"	"86.1"	"101.1"	"104.0"	"135.0"	"262.0"	"737.9"	"1350.0"	"1908.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q08752"	"Peptidyl-prolyl cis-trans isomerase D OS=Homo sapiens OX=9606 GN=PPID PE=1 SV=3"	"22"	"7"	"11"	"7"	"370"	"40.7"	"7.21"	"1664.40"	"24.78"	"4"	"7"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00160, Pf13176"	"5481"	"ENSG00000171497"	"PPID"	"B2R9V2; hsa:5481; Q08752"	"Alzheimer's disease and miRNA effects; NO/cGMP/PKG mediated neuroprotection; Alzheimer's disease"	"ESR-mediated signaling"	"4"	"0"	"210.2"	"191.0"	"200.0"	"192.3"	"229.5"	"222.6"	"247.6"	"322.4"	"1150.2"	"3577.1"	"5829.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14571"	"Inositol 1,4,5-trisphosphate receptor type 2 OS=Homo sapiens OX=9606 GN=ITPR2 PE=1 SV=2"	"4"	"11"	"19"	"9"	"2701"	"307.9"	"6.43"	"4031.32"	"24.63"	"10"	"7"	"stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf00520, Pf01365, Pf02815, Pf08454, Pf08709"	"3709"	"ENSG00000123104"	"ITPR2"	"hsa:3709; O94773; Q14571"	"Alzheimer's disease and miRNA effects; Myometrial relaxation and contraction pathways; Vitamin D-sensitive calcium signaling in depression; Thyroid hormones production and peripheral downstream signaling effects; Alzheimer's disease; GDNF signaling; Calcium regulation in cardiac cells"	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Ion homeostasis; Role of phospholipids in phagocytosis; FCERI mediated Ca+2 mobilization; FCGR3A-mediated IL10 synthesis; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Ca2+ pathway; VEGFR2 mediated cell proliferation; Elevation of cytosolic Ca2+ levels; PLC beta mediated events; DAG and IP3 signaling; CLEC7A (Dectin-1) induces NFAT activation; Effects of PIP2 hydrolysis"	"21"	"2"	"908.5"	"753.7"	"901.8"	"787.7"	"831.8"	"848.5"	"1016.2"	"1131.9"	"1815.5"	"3760.3"	"6341.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13642"	"Four and a half LIM domains protein 1 OS=Homo sapiens OX=9606 GN=FHL1 PE=1 SV=4"	"21"	"6"	"11"	"6"	"323"	"36.2"	"8.97"	"2010.02"	"24.52"	"4"	"5"	"other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00412"	"2273"	"ENSG00000022267"	"FHL1"	"B7Z5T4; B7Z793; hsa:2273; O95212; Q13230; Q13642; Q13645; Q5JXI7; Q5M7Y6; Q6IB30; Q9NZ40; Q9UKZ8; Q9Y630"	"Notch signaling pathway"	""	"1"	"0"	"845.8"	"769.3"	"845.2"	"743.7"	"822.9"	"638.9"	"967.1"	"1135.7"	"1750.3"	"2322.3"	"2549.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NX58"	"Cell growth-regulating nucleolar protein OS=Homo sapiens OX=9606 GN=LYAR PE=1 SV=2"	"23"	"6"	"12"	"6"	"379"	"43.6"	"9.54"	"2373.66"	"24.40"	"5"	"5"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"609.0"	"489.6"	"645.9"	"524.2"	"617.6"	"670.3"	"758.6"	"839.9"	"1456.8"	"1873.4"	"2188.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P26599"	"Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1"	"23"	"8"	"12"	"7"	"531"	"57.2"	"9.17"	"1931.72"	"24.39"	"5"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf11835, Pf13893"	"749887"	"ENSPPYG00000009289; ENSPTRG00000010165"	"PTBP1"	"A0A2J8IKP3; A0A2J8RA51; A0A6D2WFY9; A0A8I5YPF9; K7AXA8"	""	""	"0"	"1"	"625.9"	"591.6"	"670.1"	"587.2"	"662.3"	"597.4"	"719.3"	"819.3"	"1250.5"	"2223.4"	"3168.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14151"	"Scaffold attachment factor B2 OS=Homo sapiens OX=9606 GN=SAFB2 PE=1 SV=1"	"7"	"7"	"14"	"3"	"953"	"107.4"	"6.16"	"2120.70"	"24.36"	"5"	"7"	"developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf02037"	"9667"	"ENSG00000130254"	"SAFB2"	"B4DKG3; hsa:9667; Q14151; Q8TB13"	""	""	"0"	"0"	"462.0"	"339.6"	"462.9"	"414.2"	"399.9"	"436.5"	"527.5"	"574.1"	"803.6"	"1524.9"	"2796.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55084"	"Trifunctional enzyme subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=HADHB PE=1 SV=3"	"20"	"10"	"18"	"9"	"474"	"51.3"	"9.41"	"4567.59"	"24.30"	"9"	"7"	"other metabolic processes;other biological processes"	"other membranes;mitochondrion;ER/Golgi"	"nucleic acid binding activity;other molecular function"	"Pf00108, Pf02803"	"3032"	"ENSG00000138029"	"HADHB"	"B2RB16; B4E2W0; hsa:3032; O14969; P55084; Q53TA6; Q96C77; Q9H3F5; Q9T2V8"	"Fatty acid beta-oxidation; Valproic acid pathway; Female steroid hormones in cardiomyocyte energy metabolism; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Acyl chain remodeling of CL; mitochondrial fatty acid beta-oxidation of unsaturated fatty acids; Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA; Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of myristoyl-CoA to lauroyl-CoA; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA; Beta oxidation of palmitoyl-CoA to myristoyl-CoA"	"12"	"0"	"495.1"	"453.1"	"521.9"	"460.5"	"532.7"	"516.6"	"631.5"	"736.3"	"1217.6"	"2426.2"	"5202.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKY7"	"Protein CDV3 homolog OS=Homo sapiens OX=9606 GN=CDV3 PE=1 SV=1"	"31"	"6"	"10"	"6"	"258"	"27.3"	"6.40"	"2314.74"	"24.28"	"5"	"5"	""	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf15359"	"55573"	"ENSG00000091527"	"CDV3"	"B3KUC2; hsa:55573; Q96IP9; Q9UKY7"	""	""	"0"	"0"	"161.9"	"131.4"	"153.9"	"142.1"	"150.7"	"173.6"	"233.3"	"555.5"	"3625.1"	"5437.9"	"6142.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99733"	"Nucleosome assembly protein 1-like 4 OS=Homo sapiens OX=9606 GN=NAP1L4 PE=1 SV=1"	"23"	"8"	"14"	"6"	"375"	"42.8"	"4.69"	"2131.99"	"24.25"	"7"	"7"	"cell organization and biogenesis"	"nucleus;other cell component"	"other molecular function"	"Pf00956"	"4676"	"ENSG00000205531; ENSG00000273562"	"NAP1L4"	"B2R6J4; F5HFY4; hsa:4676; Q99733"	""	""	"0"	"2"	"772.7"	"761.5"	"765.3"	"666.0"	"758.3"	"796.1"	"913.9"	"1107.0"	"1648.8"	"2528.0"	"4010.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3Y2"	"Chromatin target of PRMT1 protein OS=Homo sapiens OX=9606 GN=CHTOP PE=1 SV=2"	"19"	"4"	"13"	"4"	"248"	"26.4"	"12.23"	"3296.84"	"24.18"	"4"	"3"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf13865"	"26097"	"ENSG00000160679"	"CHTOP"	"D3DV55; hsa:26097; Q0VAQ8; Q2VPI9; Q5T7Y8; Q5T7Y9; Q5T7Z0; Q6NSM4; Q6PB28; Q8WYT9; Q9BUC5; Q9H034; Q9H2L0; Q9Y3Y2"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"3"	"0"	"561.9"	"552.5"	"591.5"	"466.6"	"525.3"	"566.7"	"671.2"	"801.3"	"1194.0"	"1963.9"	"3316.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NZI8"	"Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2"	"12"	"5"	"10"	"4"	"577"	"63.4"	"9.20"	"2007.52"	"24.12"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf00076"	"10642"	"ENSG00000159217"	"IGF2BP1"	"C9JT33; hsa:10642; Q9NZI8"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; eIF5A regulation in response to inhibition of the nuclear export system"	"MAPK6/MAPK4 signaling; Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"	"4"	"0"	"361.8"	"394.6"	"406.7"	"333.7"	"380.0"	"403.5"	"469.7"	"536.2"	"658.4"	"923.2"	"1392.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62263"	"40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3"	"41"	"5"	"8"	"5"	"151"	"16.3"	"10.05"	"1457.70"	"24.09"	"3"	"5"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00411"	"6208"	"ENSG00000164587"	"RPS14"	"B2R5G5; D3DQG5; hsa:6208; P06366; P62263; Q5BJI0"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; rRNA modification in the nucleus and cytosol; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"20"	"0"	"157.3"	"157.3"	"155.1"	"140.4"	"150.0"	"162.1"	"215.4"	"264.7"	"483.7"	"748.4"	"1163.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86YQ8"	"Copine-8 OS=Homo sapiens OX=9606 GN=CPNE8 PE=1 SV=2"	"16"	"7"	"12"	"6"	"564"	"63.1"	"5.96"	"2217.10"	"24.06"	"6"	"6"	"other biological processes"	"plasma membrane;other membranes"	"other molecular function"	"Pf00168, Pf07002"	"144402"	"ENSG00000139117"	"CPNE8"	"hsa:144402; Q2TB41; Q86VY2; Q86YQ8"	""	"RHOQ GTPase cycle; RHOJ GTPase cycle; RHOD GTPase cycle; CDC42 GTPase cycle"	"4"	"1"	"148.5"	"128.0"	"159.0"	"147.1"	"161.1"	"146.1"	"200.9"	"220.1"	"693.9"	"2294.9"	"3836.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12788"	"Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2"	"10"	"5"	"10"	"5"	"808"	"89.0"	"6.90"	"1667.92"	"23.84"	"3"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00400, Pf08625"	"10607"	"ENSG00000183751"	"TBL3"	"hsa:10607; Q12788; Q59GD6; Q8IVB7; Q96A78"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"101.0"	"102.3"	"114.0"	"105.3"	"121.3"	"103.5"	"151.6"	"249.0"	"623.7"	"1282.0"	"1601.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13217"	"DnaJ homolog subfamily C member 3 OS=Homo sapiens OX=9606 GN=DNAJC3 PE=1 SV=1"	"18"	"9"	"16"	"9"	"504"	"57.5"	"6.15"	"3286.46"	"23.83"	"9"	"7"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00226, Pf00515, Pf13181, Pf13432"	"5611"	"ENSG00000102580"	"DNAJC3"	"hsa:5611; Q13217; Q86WT9; Q8N4N2"	"Photodynamic therapy-induced unfolded protein response"	"Neutrophil degranulation; Viral mRNA Translation; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; XBP1(S) activates chaperone genes"	"6"	"0"	"407.0"	"391.2"	"410.5"	"368.5"	"490.3"	"477.1"	"530.8"	"724.9"	"2231.7"	"4417.7"	"5729.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5X1"	"Sorting nexin-9 OS=Homo sapiens OX=9606 GN=SNX9 PE=1 SV=1"	"15"	"7"	"13"	"7"	"595"	"66.6"	"5.58"	"2834.64"	"23.81"	"7"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf00018, Pf00787, Pf10456"	"51429"	"ENSG00000130340"	"SNX9"	"hsa:51429; Q9BSI7; Q9BVM1; Q9UJH6; Q9UP20; Q9Y5X1"	""	"Clathrin-mediated endocytosis; Golgi Associated Vesicle Biogenesis"	"2"	"0"	"198.3"	"177.1"	"254.8"	"227.6"	"375.3"	"731.4"	"1488.7"	"2280.5"	"1886.8"	"1528.1"	"1622.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43660"	"Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1"	"17"	"5"	"10"	"5"	"514"	"57.2"	"9.17"	"2442.63"	"23.76"	"4"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;nucleus;other cell component"	""	"Pf00400"	"5356"	"ENSG00000171566"	"PLRG1"	"B3KMK4; hsa:5356; O43660; Q3KQY5; Q8WUD8"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"233.4"	"202.0"	"258.1"	"229.9"	"228.0"	"242.8"	"279.1"	"366.6"	"822.9"	"1533.6"	"2183.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60749"	"Sorting nexin-2 OS=Homo sapiens OX=9606 GN=SNX2 PE=1 SV=2"	"12"	"6"	"10"	"4"	"519"	"58.4"	"5.12"	"1102.93"	"23.73"	"2"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00787, Pf03700, Pf09325"	"6643"	"ENSG00000205302"	"SNX2"	"B3KN44; B4DEK4; B7Z408; hsa:6643; O43650; O60749; P82862; Q53XK8; Q597H6; Q9BTS8"	""	"Golgi Associated Vesicle Biogenesis"	"1"	"1"	"126.7"	"116.7"	"153.8"	"132.8"	"143.0"	"166.8"	"175.9"	"241.2"	"532.9"	"1814.5"	"3419.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5TAP6"	"U3 small nucleolar RNA-associated protein 14 homolog C OS=Homo sapiens OX=9606 GN=UTP14C PE=1 SV=1"	"9"	"5"	"11"	"1"	"766"	"87.1"	"7.15"	"2474.82"	"23.67"	"4"	"5"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf04615"	"9724"	"ENSG00000253797"	"UTP14C"	"hsa:9724; Q5FWG3; Q5TAP6; Q92555"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"20.1"	"16.9"	"33.0"	"24.0"	"33.5"	"31.4"	"30.6"	"31.0"	"40.3"	"40.6"	"40.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q00341"	"Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2"	"9"	"7"	"12"	"7"	"1268"	"141.4"	"6.87"	"1818.83"	"23.65"	"5"	"7"	"other metabolic processes;transport"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013"	"3069"	"ENSG00000115677"	"HDLBP"	"B4DTQ2; E7EM71; hsa:3069; Q00341; Q53QU2; Q9UCY3"	"2q37 copy number variation syndrome"	"HDL clearance"	"2"	"0"	"146.8"	"121.4"	"220.8"	"153.3"	"196.7"	"162.7"	"205.3"	"255.2"	"489.3"	"1155.1"	"1605.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NFH3"	"Nucleoporin Nup43 OS=Homo sapiens OX=9606 GN=NUP43 PE=1 SV=1"	"9"	"3"	"12"	"3"	"380"	"42.1"	"5.63"	"2283.99"	"23.62"	"3"	"3"	"cell cycle OR cell proliferation;transport;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf00400"	"348995"	"ENSG00000120253"	"NUP43"	"B4E2F0; hsa:348995; Q8NFH3; Q9H8S0"	""	"Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Regulation of HSF1-mediated heat shock response; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; ISG15 antiviral mechanism; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Vpr-mediated nuclear import of PICs; Transport of Mature mRNA derived from an Intron-Containing Transcript; tRNA processing in the nucleus; HCMV Late Events; HCMV Early Events; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); SARS-CoV-2 activates/modulates innate and adaptive immune responses; Postmitotic nuclear pore complex (NPC) reformation"	"35"	"0"	"200.9"	"172.2"	"239.8"	"213.0"	"242.4"	"214.9"	"275.7"	"355.8"	"516.7"	"635.1"	"795.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04908"	"Histone H2A type 1-B/E OS=Homo sapiens OX=9606 GN=H2AC4 PE=1 SV=2"	"32"	"3"	"14"	"1"	"130"	"14.1"	"11.05"	"2402.59"	"23.62"	"3"	"3"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125, Pf16211"	"3012; 8335"	"ENSG00000277075; ENSG00000278463"	"H2AC4; H2AC8"	"hsa:3012; hsa:8335; P04908; P28001; Q76P63"	"Proteasome degradation"	"Amyloid fiber formation; Meiotic synapsis; HCMV Late Events; UCH proteinases; Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; HCMV Early Events; Transcriptional regulation by small RNAs; Deposition of new CENPA-containing nucleosomes at the centromere; B-WICH complex positively regulates rRNA expression; Formation of the beta-catenin:TCF transactivating complex; Oxidative Stress Induced Senescence; HDACs deacetylate histones; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Metalloprotease DUBs; Pre-NOTCH Transcription and Translation; Senescence-Associated Secretory Phenotype (SASP); RMTs methylate histone arginines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; HATs acetylate histones; RNA Polymerase I Promoter Escape; Meiotic recombination; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Packaging Of Telomere Ends; Condensation of Prophase Chromosomes; DNA Damage/Telomere Stress Induced Senescence; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis"	"42"	"0"	"28.5"	"155.8"	"34.4"	"25.0"	"35.3"	"36.7"	"42.9"	"51.9"	"72.6"	"160.4"	"208.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5S9"	"RNA-binding protein 8A OS=Homo sapiens OX=9606 GN=RBM8A PE=1 SV=1"	"31"	"3"	"8"	"3"	"174"	"19.9"	"5.72"	"2473.92"	"23.61"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"9939"	"ENSG00000265241"	"RBM8A"	"B3KQI9; hsa:9939; Q6FHD1; Q6IQ40; Q9GZX8; Q9NZI4; Q9Y5S9"	""	"mRNA Splicing - Major Pathway; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing"	"6"	"0"	"116.9"	"135.0"	"95.9"	"89.2"	"123.6"	"118.0"	"144.9"	"187.3"	"229.9"	"409.7"	"832.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N488"	"RING1 and YY1-binding protein OS=Homo sapiens OX=9606 GN=RYBP PE=1 SV=2"	"36"	"5"	"7"	"5"	"228"	"24.8"	"9.63"	"794.17"	"23.60"	"2"	"5"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00641, Pf17219"	"23429"	"ENSG00000163602; ENSG00000281766"	"RYBP"	"hsa:23429; Q8N488; Q9P2W5; Q9UMW4"	""	"Transcriptional Regulation by E2F6; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"	"2"	"0"	"323.9"	"255.2"	"297.2"	"281.9"	"273.2"	"325.2"	"356.2"	"413.8"	"871.8"	"1074.2"	"1262.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IWZ3"	"Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1"	"4"	"5"	"9"	"2"	"2542"	"269.3"	"5.73"	"1383.82"	"23.54"	"2"	"5"	"stress response"	"other cell component"	""	"Pf00013, Pf12796"	"404734; 54882"	"ENSG00000131503"	"ANKHD1"	"A6NH85; hsa:404734; hsa:54882; Q149P2; Q8IWZ2; Q8IWZ3; Q8WY90; Q96G77; Q96GK0; Q9H2U0; Q9HA95; Q9NWG4; Q9UPR7"	""	""	"0"	"0"	"15.5"	"18.0"	"15.7"	"15.4"	"13.8"	"16.7"	"23.1"	"32.3"	"87.0"	"272.3"	"374.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13427"	"Peptidyl-prolyl cis-trans isomerase G OS=Homo sapiens OX=9606 GN=PPIG PE=1 SV=2"	"8"	"5"	"14"	"5"	"754"	"88.6"	"10.29"	"2446.99"	"23.42"	"5"	"5"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00160"	"9360"	"ENSG00000138398"	"PPIG"	"D3DPC5; D3DPC6; hsa:9360; O00706; Q13427; Q53R40; Q53SN4; Q96DG9"	""	"mRNA Splicing - Major Pathway; SARS-CoV-1 activates/modulates innate immune responses"	"2"	"0"	"824.5"	"707.3"	"855.6"	"708.7"	"735.3"	"787.2"	"961.4"	"1162.1"	"1530.8"	"2570.1"	"4169.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P33240"	"Cleavage stimulation factor subunit 2 OS=Homo sapiens OX=9606 GN=CSTF2 PE=1 SV=1"	"15"	"7"	"16"	"7"	"577"	"60.9"	"6.83"	"2725.63"	"23.37"	"7"	"7"	"other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf14304, Pf14327"	"1478"	"ENSG00000101811"	"CSTF2"	"hsa:1478; P33240; Q5H951; Q6LA74; Q8N502"	"mRNA processing"	"tRNA processing in the nucleus; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"6"	"0"	"524.2"	"464.3"	"630.3"	"506.5"	"585.7"	"527.1"	"614.1"	"699.4"	"1076.4"	"2135.1"	"3149.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62826"	"GTP-binding nuclear protein Ran OS=Homo sapiens OX=9606 GN=RAN PE=1 SV=3"	"22"	"4"	"9"	"4"	"216"	"24.4"	"7.49"	"1103.30"	"23.37"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00071"	"5901"	"ENSG00000132341"	"RAN"	"A8K3Z8; hsa:5901; P17080; P28746; P28747; P62826; Q6IPB2; Q86V08; Q8NI90; Q9CSP3; Q9CWI7; Q9CZA2; Q9UDJ5; Q9UEU9"	"Androgen receptor signaling pathway; miRNA biogenesis; 22q11.2 copy number variation syndrome"	"Rev-mediated nuclear export of HIV RNA; NEP/NS2 Interacts with the Cellular Export Machinery; Nuclear import of Rev protein; Transcriptional regulation by small RNAs; tRNA processing in the nucleus; Regulation of cholesterol biosynthesis by SREBP (SREBF); MicroRNA (miRNA) biogenesis; Postmitotic nuclear pore complex (NPC) reformation"	"11"	"0"	"583.6"	"452.0"	"523.0"	"533.1"	"537.1"	"518.5"	"650.1"	"787.5"	"1329.2"	"2087.1"	"2547.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25098"	"Beta-adrenergic receptor kinase 1 OS=Homo sapiens OX=9606 GN=GRK2 PE=1 SV=2"	"13"	"6"	"9"	"6"	"689"	"79.5"	"7.28"	"1241.30"	"23.34"	"4"	"5"	"cell-cell signaling;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"signal transduction activity or receptor binding;kinase activity;other molecular function"	"Pf00069, Pf00169, Pf00615"	"156"	"ENSG00000173020"	"GRK2"	"B0ZBE1; hsa:156; P25098; Q13837; Q6GTT3"	"Chemokine signaling pathway; Hedgehog signaling pathway; Hedgehog signaling pathway"	"G alpha (q) signalling events; Activation of SMO; G alpha (s) signalling events; Cargo recognition for clathrin-mediated endocytosis; Calmodulin induced events"	"8"	"0"	"103.2"	"98.7"	"134.8"	"107.2"	"113.9"	"121.5"	"150.8"	"215.5"	"651.3"	"1697.2"	"1889.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15355"	"Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1"	"14"	"6"	"13"	"6"	"546"	"59.2"	"4.36"	"2109.49"	"23.33"	"5"	"6"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf00481"	"5496"	"ENSG00000115241"	"PPM1G"	"hsa:5496; O15355"	"VEGFA-VEGFR2 signaling; mRNA processing"	""	"2"	"0"	"489.2"	"414.9"	"547.4"	"485.8"	"529.0"	"516.5"	"619.9"	"807.5"	"1107.6"	"1704.0"	"2533.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22061"	"Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens OX=9606 GN=PCMT1 PE=1 SV=4"	"22"	"5"	"15"	"5"	"227"	"24.6"	"7.21"	"3665.03"	"23.33"	"5"	"4"	"protein metabolism;other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf01135"	"5110"	"ENSG00000120265"	"PCMT1"	"A8K109; hsa:5110; J3KP72; P22061; Q14661; Q16556; Q5VYC1; Q5VYC2; Q93061; Q96II9; Q99625; Q9BQV7; Q9BQV8; Q9NP03"	"Primary ovarian insufficiency"	"Protein repair"	"2"	"0"	"909.9"	"996.1"	"1082.1"	"939.0"	"1059.7"	"1120.9"	"1362.0"	"1590.2"	"1786.7"	"2116.1"	"2592.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09012"	"U1 small nuclear ribonucleoprotein A OS=Homo sapiens OX=9606 GN=SNRPA PE=1 SV=3"	"12"	"4"	"18"	"2"	"282"	"31.3"	"9.83"	"2930.36"	"23.29"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6626"	"ENSG00000077312"	"SNRPA"	"hsa:6626; P09012"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"3"	"2212.3"	"1613.8"	"2235.9"	"1944.9"	"2126.8"	"2025.2"	"2397.8"	"2470.8"	"2756.6"	"3268.8"	"4448.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q53F19"	"Nuclear cap-binding protein subunit 3 OS=Homo sapiens OX=9606 GN=NCBP3 PE=1 SV=2"	"16"	"8"	"18"	"8"	"620"	"70.5"	"5.73"	"3425.64"	"23.25"	"8"	"7"	"RNA metabolism OR transcription;other metabolic processes;stress response;transport"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf10309"	"55421"	"ENSG00000074356"	"NCBP3"	"B3KWG7; hsa:55421; Q53F19; Q7L406; Q96FK1; Q9NXZ4"	""	""	"0"	"0"	"735.7"	"681.7"	"797.8"	"666.4"	"812.0"	"816.2"	"846.3"	"1038.6"	"1435.7"	"2183.5"	"3300.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NTI5"	"Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens OX=9606 GN=PDS5B PE=1 SV=1"	"5"	"6"	"10"	"4"	"1447"	"164.6"	"8.47"	"1236.89"	"23.25"	"4"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf20168"	"23047"	"ENSG00000083642"	"PDS5B"	"hsa:23047; Q5R3S3; Q5W0K8; Q6NSC3; Q8IXT6; Q9H5N8; Q9NTI5; Q9Y2I5; Q9Y451"	"Cohesin complex - Cornelia de Lange syndrome; 10q22q23 copy number variation"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"6"	"0"	"298.0"	"224.1"	"324.5"	"274.4"	"287.2"	"327.3"	"353.7"	"400.4"	"682.2"	"1056.2"	"1396.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5VTL8"	"Pre-mRNA-splicing factor 38B OS=Homo sapiens OX=9606 GN=PRPF38B PE=1 SV=1"	"12"	"5"	"12"	"5"	"546"	"64.4"	"10.54"	"2381.74"	"23.20"	"5"	"5"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf03371"	"55119"	"ENSG00000134186"	"PRPF38B"	"hsa:55119; Q05DD6; Q32Q58; Q5VTL8; Q5VTL9; Q6PK39; Q7Z6E2; Q86WF3; Q8IWG9; Q9NW40"	""	""	"0"	"0"	"478.1"	"392.0"	"498.6"	"419.3"	"447.9"	"446.1"	"581.5"	"663.2"	"1014.6"	"1786.8"	"2491.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96KR1"	"Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2"	"7"	"6"	"11"	"6"	"1074"	"116.9"	"9.04"	"2170.14"	"23.15"	"5"	"6"	""	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf07528, Pf12874"	"51663"	"ENSG00000056097"	"ZFR"	"B2RNR5; hsa:51663; Q05C08; Q3B7X5; Q6P5A3; Q86UA0; Q96KR1; Q9H6V4; Q9NTI1; Q9Y687"	"Exercise-induced circadian regulation"	""	"1"	"0"	"537.1"	"444.6"	"532.9"	"485.6"	"509.5"	"533.6"	"617.3"	"694.2"	"822.5"	"1167.5"	"1709.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11177"	"Pyruvate dehydrogenase E1 component subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=PDHB PE=1 SV=3"	"14"	"5"	"12"	"5"	"359"	"39.2"	"6.65"	"2331.82"	"23.13"	"5"	"5"	"other metabolic processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf02779, Pf02780"	"5162"	"ENSG00000168291"	"PDHB"	"B2R7L0; B4DDD7; hsa:5162; P11177; Q6FH45; Q9BQ27; Q9UFK3"	"Metabolic reprogramming in colon cancer; Orexin receptor pathway"	"Glyoxylate metabolism and glycine degradation; Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid"	"6"	"0"	"432.3"	"407.2"	"493.7"	"420.5"	"413.8"	"479.0"	"569.5"	"697.4"	"1159.2"	"2139.5"	"3212.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NE71"	"ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2"	"11"	"7"	"12"	"7"	"845"	"95.9"	"6.80"	"3186.28"	"22.93"	"5"	"5"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00005, Pf12848"	"23"	"ENSG00000204574; ENSG00000206490; ENSG00000225989; ENSG00000231129; ENSG00000232169; ENSG00000236149; ENSG00000236342"	"ABCF1"	"A2BF75; hsa:23; O14897; Q69YP6; Q8NE71"	"IL-18 signaling pathway"	"ABC-family proteins mediated transport"	"2"	"0"	"642.8"	"414.4"	"675.5"	"619.9"	"667.7"	"718.2"	"814.5"	"763.5"	"1744.0"	"1796.5"	"2139.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61981"	"14-3-3 protein gamma OS=Homo sapiens OX=9606 GN=YWHAG PE=1 SV=2"	"21"	"5"	"16"	"2"	"247"	"28.3"	"4.89"	"3559.17"	"22.92"	"5"	"5"	"transport;signal transduction;other biological processes"	"cytosol;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00244"	"7532"	"ENSG00000170027"	"YWHAG"	"hsa:7532; O70457; P35214; P61981; Q6FH52; Q9UDP2; Q9UN99"	"Cell cycle; Prolactin signaling pathway; Myometrial relaxation and contraction pathways; Disruption of postsynaptic signaling by CNV; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Regulation of localization of FOXO transcription factors; TP53 Regulates Metabolic Genes; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Activation of BAD and translocation to mitochondria"	"21"	"0"	"271.7"	"209.3"	"237.1"	"227.7"	"223.8"	"240.7"	"327.8"	"375.7"	"474.3"	"520.4"	"624.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94842"	"TOX high mobility group box family member 4 OS=Homo sapiens OX=9606 GN=TOX4 PE=1 SV=1"	"10"	"6"	"12"	"6"	"621"	"66.2"	"5.06"	"2242.48"	"22.85"	"6"	"6"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00505"	"9878"	"ENSG00000092203"	"TOX4"	"B4DPY8; B4DSM0; E7EV69; hsa:9878; O94842"	""	""	"0"	"0"	"529.4"	"348.1"	"525.8"	"452.7"	"512.3"	"412.5"	"558.7"	"665.5"	"1249.0"	"2361.7"	"3193.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96SY0"	"Integrator complex subunit 14 OS=Homo sapiens OX=9606 GN=INTS14 PE=1 SV=2"	"14"	"5"	"11"	"5"	"518"	"57.4"	"5.12"	"2170.68"	"22.76"	"5"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	"Pf13519, Pf19435, Pf20504"	"81556"	"ENSG00000138614"	"INTS14"	"B4DDI6; B4DVD5; hsa:81556; Q49AH8; Q96HX5; Q96SY0; Q9H0S5"	"1p36 copy number variation syndrome"	"RNA polymerase II transcribes snRNA genes"	"2"	"0"	"109.2"	"100.3"	"144.2"	"115.2"	"131.4"	"126.8"	"146.5"	"193.4"	"473.8"	"1406.8"	"2569.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z6Z7"	"E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3"	"2"	"5"	"8"	"5"	"4374"	"481.6"	"5.22"	"757.95"	"22.75"	"2"	"5"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00627, Pf00632, Pf02825, Pf06012, Pf06025, Pf14377"	"10075"	"ENSG00000086758"	"HUWE1"	"hsa:10075; O15029; Q4G2Z2; Q5H961; Q6P4D0; Q7Z6Z7; Q8NG67; Q9BUI0; Q9HCJ4; Q9NSL6; Q9P0A9"	""	"Neutrophil degranulation; Antigen processing: Ubiquitination & Proteasome degradation"	"2"	"0"	"122.5"	"142.5"	"156.8"	"133.8"	"143.2"	"125.6"	"158.7"	"195.0"	"263.9"	"501.0"	"684.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09661"	"U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2"	"31"	"7"	"13"	"7"	"255"	"28.4"	"8.62"	"2360.93"	"22.68"	"6"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf14580"	"6627"	"ENSG00000131876"	"SNRPA1"	"B2R5I6; hsa:6627; P09661; Q8TBD2"	"mRNA processing"	"mRNA Splicing - Major Pathway; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	"3"	"0"	"796.8"	"809.4"	"673.6"	"644.6"	"728.4"	"711.8"	"886.8"	"1013.0"	"1165.8"	"1649.4"	"2537.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62995"	"Transformer-2 protein homolog beta OS=Homo sapiens OX=9606 GN=TRA2B PE=1 SV=1"	"19"	"6"	"14"	"6"	"288"	"33.6"	"11.25"	"2293.63"	"22.67"	"5"	"6"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6434"	"ENSG00000136527"	"TRA2B"	"B4DVK2; D3DNU3; hsa:6434; O15449; P62995; Q15815; Q64283"	"mRNA processing"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle"	"5"	"0"	"1286.7"	"1353.5"	"1283.0"	"1126.4"	"1222.0"	"1153.9"	"1427.8"	"1657.6"	"1721.8"	"2201.5"	"3435.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H3G5"	"Probable serine carboxypeptidase CPVL OS=Homo sapiens OX=9606 GN=CPVL PE=1 SV=2"	"11"	"4"	"8"	"4"	"476"	"54.1"	"5.62"	"1151.27"	"22.67"	"2"	"4"	"protein metabolism"	""	"other molecular function"	"Pf00450"	"54504"	"ENSG00000106066"	"CPVL"	"A4D1A4; hsa:54504; Q6UX20; Q8NBL7; Q96AR7; Q9H3G5; Q9HB41"	""	""	"0"	"0"	"139.6"	"111.7"	"169.4"	"121.6"	"142.2"	"166.3"	"191.5"	"257.0"	"822.0"	"2578.8"	"4544.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15144"	"Actin-related protein 2/3 complex subunit 2 OS=Homo sapiens OX=9606 GN=ARPC2 PE=1 SV=1"	"22"	"7"	"13"	"7"	"300"	"34.3"	"7.36"	"2305.67"	"22.63"	"6"	"7"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity"	"Pf04045"	"10109"	"ENSG00000163466"	"ARPC2"	"hsa:10109; O15144; Q92801; Q9P1D4"	"Pathogenic Escherichia coli infection"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Clathrin-mediated endocytosis; EPHB-mediated forward signaling"	"6"	"0"	"192.4"	"203.2"	"212.9"	"180.7"	"227.9"	"203.5"	"239.9"	"360.9"	"1802.9"	"4628.5"	"5753.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IX01"	"SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2"	"9"	"8"	"14"	"8"	"1082"	"120.1"	"7.28"	"2713.49"	"22.61"	"7"	"7"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf01585, Pf01805"	"10147"	"ENSG00000064607"	"SUGP2"	"C9JI71; hsa:10147; O15071; O60369; Q5JPH7; Q8IX01; Q8WUF7"	"mRNA processing"	""	"1"	"0"	"450.6"	"427.3"	"515.1"	"439.1"	"487.9"	"510.5"	"589.1"	"712.2"	"1468.7"	"2930.2"	"4174.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01130"	"Serine/arginine-rich splicing factor 2 OS=Homo sapiens OX=9606 GN=SRSF2 PE=1 SV=4"	"17"	"4"	"9"	"4"	"221"	"25.5"	"11.85"	"1301.99"	"22.57"	"3"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00076"	"6427"	"ENSG00000161547"	"SRSF2"	"B3KWD5; B4DN89; H0YG49; hsa:6427; Q01130"	"mRNA processing"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; mRNA Splicing - Minor Pathway"	"7"	"0"	"324.7"	"343.3"	"329.5"	"325.5"	"341.3"	"334.7"	"424.1"	"511.3"	"606.9"	"1017.4"	"1660.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50395"	"Rab GDP dissociation inhibitor beta OS=Homo sapiens OX=9606 GN=GDI2 PE=1 SV=2"	"15"	"5"	"7"	"5"	"445"	"50.6"	"6.47"	"1046.52"	"22.53"	"2"	"5"	"transport;signal transduction;other biological processes"	"non-structural extracellular;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00996"	"2665"	"ENSG00000057608"	"GDI2"	"hsa:2665; O43928; P50395; Q5SX88; Q9UQM6"	""	"Neutrophil degranulation; RAB GEFs exchange GTP for GDP on RABs"	"2"	"0"	"72.9"	"69.0"	"91.4"	"83.7"	"92.5"	"80.2"	"88.4"	"126.2"	"244.8"	"961.0"	"3665.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35612"	"Beta-adducin OS=Homo sapiens OX=9606 GN=ADD2 PE=1 SV=3"	"15"	"9"	"13"	"7"	"726"	"80.8"	"5.92"	"2423.71"	"22.45"	"6"	"7"	"cell adhesion;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00596"	"119"	"ENSG00000075340"	"ADD2"	"A8K4P2; B4DM17; D6W5G7; D6W5G8; hsa:119; P35612; Q13482; Q16412; Q59G82; Q5U5P4; Q6P0P2; Q6PGQ4; Q7Z688; Q7Z689; Q7Z690; Q7Z691"	""	"Miscellaneous transport and binding events"	"1"	"0"	"206.7"	"157.0"	"231.5"	"198.8"	"212.2"	"221.8"	"236.9"	"306.7"	"1394.7"	"2041.9"	"2419.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00425"	"Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2"	"10"	"5"	"12"	"3"	"579"	"63.7"	"8.87"	"2241.80"	"22.38"	"5"	"5"	"protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf00076"	"10643"	"ENSG00000136231"	"IGF2BP3"	"A0A4Z5; hsa:10643; O00425; Q63HM0; Q6MZZ2; Q86VB1"	""	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"	"1"	"2"	"314.0"	"329.4"	"371.3"	"318.2"	"334.1"	"337.1"	"417.1"	"501.5"	"718.2"	"1150.2"	"1799.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P36873"	"Serine/threonine-protein phosphatase PP1-gamma catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CC PE=1 SV=1"	"24"	"6"	"11"	"2"	"323"	"37.0"	"6.54"	"1972.06"	"22.32"	"5"	"6"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00149, Pf16891"	"5501"	"ENSG00000186298"	"PPP1CC"	"hsa:5501; P36873"	"Common pathways underlying drug addiction; Focal adhesion; Hippo-Merlin signaling dysregulation; Neuroinflammation and glutamatergic signaling"	"Separation of Sister Chromatids; Triglyceride catabolism; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Circadian Clock; RAF activation; SHOC2 M1731 mutant abolishes MRAS complex function; Gain-of-function MRAS complexes activate RAF signaling; Downregulation of TGF-beta receptor signaling"	"16"	"0"	"231.4"	"192.9"	"221.2"	"212.8"	"238.8"	"252.0"	"250.0"	"282.9"	"544.3"	"868.2"	"1214.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62633"	"Cellular nucleic acid-binding protein OS=Homo sapiens OX=9606 GN=CNBP PE=1 SV=1"	"31"	"4"	"5"	"4"	"177"	"19.5"	"7.71"	""	"22.30"	""	"4"	"DNA metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00098"	"7555"	"ENSG00000169714"	"CNBP"	"A8K7V4; B2RAV9; B4DP17; D3DNB9; D3DNC0; D3DNC1; E9PDR7; hsa:7555; P20694; P62633; Q4JGY0; Q4JGY1; Q5QJR0; Q5U0E9; Q6PJI7; Q96NV3"	""	"SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"1"	"0"	"393.0"	"432.8"	"307.2"	"320.1"	"303.1"	"156.8"	"377.2"	"523.2"	"949.5"	"1607.4"	"1760.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12996"	"Cleavage stimulation factor subunit 3 OS=Homo sapiens OX=9606 GN=CSTF3 PE=1 SV=1"	"15"	"7"	"13"	"7"	"717"	"82.9"	"8.12"	"3296.63"	"22.29"	"6"	"6"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf05843"	"1479"	"ENSG00000176102"	"CSTF3"	"A8K471; D3DR04; E9PB40; hsa:1479; Q12996; Q32P22; Q96FQ8; Q96QD6; Q96QK4"	"mRNA processing"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"5"	"0"	"252.9"	"317.9"	"266.5"	"220.2"	"267.2"	"242.9"	"363.2"	"541.4"	"1167.5"	"3135.3"	"4697.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50579"	"Methionine aminopeptidase 2 OS=Homo sapiens OX=9606 GN=METAP2 PE=1 SV=1"	"17"	"5"	"8"	"5"	"478"	"52.9"	"5.82"	"1127.50"	"22.20"	"3"	"5"	"protein metabolism;other metabolic processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00557"	"10988"	"ENSG00000111142"	"METAP2"	"B2RDI8; B4DUX5; G3XA91; hsa:10988; P50579; Q8NB11"	""	"Inactivation, recovery and regulation of the phototransduction cascade"	"1"	"0"	"77.3"	"66.6"	"89.9"	"78.1"	"88.7"	"80.2"	"102.8"	"138.4"	"991.6"	"1149.9"	"1051.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15007"	"Pre-mRNA-splicing regulator WTAP OS=Homo sapiens OX=9606 GN=WTAP PE=1 SV=2"	"15"	"4"	"10"	"4"	"396"	"44.2"	"5.19"	"2102.64"	"22.18"	"4"	"4"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf17098"	"9589"	"ENSG00000146457"	"WTAP"	"hsa:9589; Q15007; Q5TCL8; Q5TCL9; Q96T28; Q9BYJ7; Q9H4E2"	""	"Processing of Capped Intron-Containing Pre-mRNA"	"1"	"0"	"190.8"	"154.6"	"216.2"	"178.8"	"183.6"	"204.5"	"237.5"	"292.9"	"623.8"	"818.9"	"1597.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11171"	"Protein 4.1 OS=Homo sapiens OX=9606 GN=EPB41 PE=1 SV=4"	"10"	"8"	"14"	"6"	"864"	"97.0"	"5.58"	"2665.17"	"22.18"	"8"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf04382, Pf05902, Pf08736, Pf09379, Pf09380"	"2035"	"ENSG00000159023"	"EPB41"	"B1ALH8; B1ALH9; D3DPM9; D3DPN0; hsa:2035; P11171; P11176; Q14245; Q5TB35; Q5VXN8; Q8IXV9; Q9Y578; Q9Y579"	"VEGFA-VEGFR2 signaling; Splicing factor NOVA regulated synaptic proteins; IL-18 signaling pathway"	"Neurexins and neuroligins"	"4"	"0"	"768.5"	"537.5"	"781.5"	"677.5"	"704.3"	"783.5"	"891.4"	"1253.5"	"2552.6"	"1557.2"	"1635.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NFP7"	"Diphosphoinositol polyphosphate phosphohydrolase 3-alpha OS=Homo sapiens OX=9606 GN=NUDT10 PE=1 SV=1"	"32"	"6"	"13"	"2"	"164"	"18.5"	"5.68"	"2543.63"	"22.17"	"5"	"6"	"other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00293"	"170685"	"ENSG00000122824"	"NUDT10"	"A8K7D7; D3DX69; hsa:170685; Q86VK1; Q86VR0; Q8NFP7"	""	"Synthesis of pyrophosphates in the cytosol"	"1"	"0"	"41.7"	"36.0"	"50.2"	"36.1"	"46.8"	"50.7"	"75.0"	"135.0"	"374.0"	"711.0"	"1046.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07196"	"Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3"	"14"	"7"	"14"	"6"	"543"	"61.5"	"4.65"	"2824.68"	"22.15"	"6"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00038, Pf04732"	"4747"	"ENSG00000277586"	"NEFL"	"B9ZVN2; hsa:4747; P07196; Q16154; Q8IU72"	"Amyotrophic lateral sclerosis (ALS); Physico-chemical features and toxicity-associated pathways; NO/cGMP/PKG mediated neuroprotection; Ciliary landscape; Intracellular trafficking proteins involved in CMT neuropathy; CCL18 signaling pathway"	"Assembly and cell surface presentation of NMDA receptors; RAF/MAP kinase cascade; Ras activation upon Ca2+ influx through NMDA receptor; Unblocking of NMDA receptors, glutamate binding and activation; Negative regulation of NMDA receptor-mediated neuronal transmission; Long-term potentiation"	"12"	"0"	"750.2"	"698.5"	"746.7"	"617.4"	"758.0"	"701.0"	"819.6"	"931.0"	"1238.9"	"1704.4"	"2388.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75792"	"Ribonuclease H2 subunit A OS=Homo sapiens OX=9606 GN=RNASEH2A PE=1 SV=2"	"24"	"5"	"10"	"5"	"299"	"33.4"	"5.25"	"2250.62"	"22.13"	"5"	"5"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01351"	"10535"	"ENSG00000104889"	"RNASEH2A"	"B2RCY1; hsa:10535; O75792; Q96F11"	""	""	"0"	"0"	"152.9"	"124.3"	"179.8"	"150.6"	"180.3"	"161.5"	"197.3"	"271.8"	"1071.8"	"2211.1"	"3011.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12959"	"Disks large homolog 1 OS=Homo sapiens OX=9606 GN=DLG1 PE=1 SV=2"	"9"	"7"	"12"	"6"	"904"	"100.4"	"5.76"	"2346.24"	"22.13"	"6"	"6"	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"extracellular matrix;plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;kinase activity;other molecular function"	"Pf00018, Pf00595, Pf00625, Pf09058, Pf10600, Pf10608"	"1739"	"ENSG00000075711"	"DLG1"	"A5YKK7; B4DGU1; B4DGZ8; B7ZMM0; B9EIQ5; D3DXB8; D3DXB9; E7EWL7; E9PG21; hsa:1739; Q12958; Q12959"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection; Disruption of postsynaptic signaling by CNV; 3q29 copy number variation syndrome"	"Assembly and cell surface presentation of NMDA receptors; RAF/MAP kinase cascade; Ras activation upon Ca2+ influx through NMDA receptor; Unblocking of NMDA receptors, glutamate binding and activation; Synaptic adhesion-like molecules; Negative regulation of NMDA receptor-mediated neuronal transmission; Long-term potentiation; Trafficking of AMPA receptors; NrCAM interactions; Activation of Ca-permeable Kainate Receptor"	"14"	"1"	"199.6"	"186.4"	"204.2"	"187.9"	"199.8"	"220.1"	"250.8"	"354.1"	"1156.7"	"2108.1"	"2651.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62314"	"Small nuclear ribonucleoprotein Sm D1 OS=Homo sapiens OX=9606 GN=SNRPD1 PE=1 SV=1"	"37"	"3"	"12"	"3"	"119"	"13.3"	"11.56"	"2507.59"	"22.04"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01423"	"6632"	"ENSG00000167088"	"SNRPD1"	"B5BTZ1; hsa:6632; P13641; P62314"	"mRNA processing"	"mRNA Splicing - Major Pathway; SARS-CoV-2 modulates host translation machinery; snRNP Assembly; mRNA Splicing - Minor Pathway"	"5"	"0"	"156.4"	"221.1"	"192.8"	"135.9"	"189.1"	"185.8"	"208.3"	"237.4"	"366.4"	"666.2"	"1073.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BUJ2"	"Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2"	"11"	"8"	"13"	"7"	"856"	"95.7"	"6.92"	"2251.50"	"22.01"	"6"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00622, Pf02037, Pf13671"	"11100"	"ENSG00000105323"	"HNRNPUL1"	"B3KMW7; hsa:11100; O76022; Q6ZSZ0; Q7L8P4; Q8N6Z4; Q96G37; Q9BUJ2; Q9HAL3; Q9UG75"	""	""	"0"	"0"	"554.7"	"475.9"	"546.4"	"530.1"	"581.5"	"579.3"	"643.3"	"814.8"	"1159.9"	"1903.7"	"2750.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UNE7"	"E3 ubiquitin-protein ligase CHIP OS=Homo sapiens OX=9606 GN=STUB1 PE=1 SV=2"	"28"	"7"	"12"	"7"	"303"	"34.8"	"5.87"	"2088.96"	"22.00"	"6"	"6"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf04564, Pf12895, Pf18391"	"10273"	"ENSG00000103266"	"STUB1"	"A2IDB9; hsa:10273; O60526; Q969U2; Q9HBT1; Q9UNE7"	"Androgen receptor signaling pathway; Parkin-ubiquitin proteasomal system pathway"	"Antigen processing: Ubiquitination & Proteasome degradation; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Regulation of TNFR1 signaling; Regulation of necroptotic cell death; Downregulation of ERBB2 signaling; Downregulation of TGF-beta receptor signaling"	"10"	"0"	"349.2"	"387.6"	"360.2"	"330.3"	"406.8"	"392.6"	"462.5"	"660.8"	"1020.1"	"2235.7"	"3703.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NYL9"	"Tropomodulin-3 OS=Homo sapiens OX=9606 GN=TMOD3 PE=1 SV=1"	"24"	"5"	"9"	"5"	"352"	"39.6"	"5.19"	"2120.47"	"21.88"	"4"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton"	"cytoskeletal activity"	"Pf03250"	"29766"	"ENSG00000138594"	"TMOD3"	"B2R6G7; hsa:29766; Q9NT43; Q9NYL9; Q9NZR0"	"VEGFA-VEGFR2 signaling"	"Striated Muscle Contraction; RND3 GTPase cycle; RHOBTB2 GTPase cycle"	"4"	"0"	"207.0"	"165.0"	"190.4"	"177.6"	"195.4"	"182.0"	"228.2"	"269.9"	"438.6"	"744.6"	"1175.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99496"	"E3 ubiquitin-protein ligase RING2 OS=Homo sapiens OX=9606 GN=RNF2 PE=1 SV=1"	"14"	"4"	"10"	"3"	"336"	"37.6"	"6.84"	"2037.24"	"21.86"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf13923, Pf16207"	"6045"	"ENSG00000121481"	"RNF2"	"B2RBS7; B3KRH1; hsa:6045; Q5TEN1; Q5TEN2; Q99496"	"FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; Pleural mesothelioma"	"Oxidative Stress Induced Senescence; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins"	"11"	"0"	"94.8"	"138.3"	"112.0"	"95.1"	"124.8"	"126.0"	"122.0"	"187.1"	"387.0"	"846.1"	"1245.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N163"	"Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2"	"7"	"6"	"14"	"6"	"923"	"102.8"	"5.22"	"2301.17"	"21.82"	"6"	"6"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytoskeleton;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf14443, Pf14444, Pf19256, Pf19257"	"57805"	"ENSG00000158941"	"CCAR2"	"A6NL03; B2RB79; D3DSR6; hsa:57805; Q6P0Q9; Q8N163; Q8N3G7; Q8N8M1; Q8TF34; Q9H9Q9; Q9HD12; Q9NT55"	"TAR syndrome"	"Regulation of HSF1-mediated heat shock response"	"2"	"0"	"652.5"	"652.4"	"732.4"	"619.1"	"695.2"	"714.6"	"830.1"	"1069.2"	"1342.3"	"2058.8"	"2937.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P48444"	"Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1"	"14"	"7"	"13"	"7"	"511"	"57.2"	"6.21"	"3136.34"	"21.82"	"7"	"6"	"transport;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi"	""	"Pf00928, Pf01217"	"372"	"ENSG00000095139"	"ARCN1"	"B4E1X2; E9PEU4; hsa:372; P48444; Q52M80"	"miR-517 relationship with ARCN1 and USP1"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport"	"3"	"0"	"415.8"	"389.5"	"424.0"	"392.1"	"457.1"	"433.2"	"471.7"	"540.8"	"952.7"	"3231.8"	"5432.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P39023"	"60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2"	"17"	"8"	"16"	"8"	"403"	"46.1"	"10.18"	"2366.88"	"21.79"	"7"	"7"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00297"	"6122"	"ENSG00000100316"	"RPL3"	"B2RDV9; hsa:6122; P39023; Q15548; Q5I0G0"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"801.0"	"765.0"	"812.5"	"702.9"	"892.5"	"875.3"	"967.9"	"1329.1"	"2261.8"	"4333.5"	"6988.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N1G4"	"Leucine-rich repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=LRRC47 PE=1 SV=1"	"13"	"6"	"11"	"6"	"583"	"63.4"	"8.28"	"1964.71"	"21.77"	"5"	"6"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	""	"other molecular function"	"Pf00560, Pf03483, Pf12799"	"57470"	"ENSG00000130764"	"LRRC47"	"hsa:57470; Q8N1G4; Q9ULN5"	""	""	"0"	"0"	"230.8"	"226.4"	"274.1"	"204.3"	"251.1"	"293.5"	"330.2"	"474.3"	"1629.6"	"1856.7"	"1683.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95757"	"Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3"	"9"	"7"	"13"	"4"	"839"	"94.5"	"5.88"	"1974.35"	"21.76"	"6"	"7"	"protein metabolism;other metabolic processes;stress response"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00012"	"22824"	"ENSG00000164070"	"HSPA4L"	"A2ICT2; hsa:22824; O95757; Q4W5M5; Q8IWA2"	""	"Regulation of HSF1-mediated heat shock response"	"1"	"0"	"108.4"	"96.2"	"124.5"	"117.3"	"124.9"	"141.7"	"147.4"	"186.3"	"283.5"	"506.7"	"846.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15291"	"Retinoblastoma-binding protein 5 OS=Homo sapiens OX=9606 GN=RBBP5 PE=1 SV=2"	"14"	"5"	"8"	"5"	"538"	"59.1"	"5.10"	"953.62"	"21.73"	"3"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00400"	"5929"	"ENSG00000117222"	"RBBP5"	"A8K272; hsa:5929; Q15291; Q7Z6D8; Q8NDZ7"	"Kleefstra syndrome"	"Neddylation; Formation of WDR5-containing histone-modifying complexes; Formation of the beta-catenin:TCF transactivating complex; Deactivation of the beta-catenin transactivating complex; Activation of anterior HOX genes in hindbrain development during early embryogenesis; PKMTs methylate histone lysines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"	"8"	"0"	"144.5"	"124.0"	"190.8"	"162.6"	"195.2"	"191.5"	"196.4"	"253.4"	"632.9"	"1475.3"	"2282.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00505"	"Importin subunit alpha-4 OS=Homo sapiens OX=9606 GN=KPNA3 PE=1 SV=2"	"11"	"4"	"8"	"3"	"521"	"57.8"	"4.94"	"1493.34"	"21.73"	"3"	"4"	"cell organization and biogenesis;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00514, Pf01749, Pf16186"	"3839"	"ENSG00000102753"	"KPNA3"	"hsa:3839; O00191; O00505; O43195; Q5JVM9; Q8IYQ9; Q96AA7"	""	"ISG15 antiviral mechanism; NS1 Mediated Effects on Host Pathways"	"2"	"1"	"174.6"	"157.4"	"193.8"	"144.9"	"181.2"	"170.9"	"230.2"	"317.6"	"486.2"	"1349.6"	"2466.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7L576"	"Cytoplasmic FMR1-interacting protein 1 OS=Homo sapiens OX=9606 GN=CYFIP1 PE=1 SV=1"	"6"	"7"	"14"	"3"	"1253"	"145.1"	"6.90"	"3315.13"	"21.70"	"7"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf05994, Pf07159"	"23191"	"ENSG00000273749; ENSG00000288461"	"CYFIP1"	"A8K6D9; hsa:23191; Q14467; Q5IED0; Q6ZSX1; Q7L576; Q9BSD9; Q9BVC7"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; Prader-Willi and Angelman syndrome; Fragile X syndrome; Disruption of postsynaptic signaling by CNV; 15q11.2 copy number variation syndrome; G13 signaling pathway"	"Neutrophil degranulation; VEGFA-VEGFR2 Pathway; RAC3 GTPase cycle; RAC1 GTPase cycle; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHOG GTPase cycle; RHO GTPases Activate WASPs and WAVEs; RAC2 GTPase cycle"	"15"	"4"	"324.5"	"234.2"	"340.5"	"305.7"	"345.7"	"297.6"	"407.8"	"568.2"	"1527.2"	"2144.2"	"2771.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6SPF0"	"Atherin OS=Homo sapiens OX=9606 GN=SAMD1 PE=1 SV=1"	"11"	"5"	"9"	"5"	"538"	"56.0"	"7.58"	"1436.49"	"21.67"	"4"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"other molecular function"	"Pf00536"	"90378"	"ENSG00000288488"	"SAMD1"	"hsa:90378; Q6P0R3; Q6PIS7; Q6SPF0; Q96IM4"	""	""	"0"	"0"	"216.0"	"208.8"	"270.6"	"225.9"	"248.0"	"228.9"	"290.4"	"343.5"	"486.8"	"757.4"	"1079.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5T4S7"	"E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens OX=9606 GN=UBR4 PE=1 SV=1"	"1"	"3"	"7"	"3"	"5183"	"573.5"	"6.04"	"789.91"	"21.66"	"2"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus"	"other molecular function"	"Pf02207, Pf13764, Pf19423"	"23352"	"ENSG00000127481"	"UBR4"	"A8MPT2; A8MQ33; A8MQB1; hsa:23352; O60646; O75050; Q4QRK5; Q5T4S7; Q5T4S8; Q5T4S9; Q5TBN8; Q5TBP2; Q6DKH8; Q6P4A4; Q7L8P7; Q8IXJ4; Q8TDN5; Q8WV67; Q9HA46; Q9P2N9; Q9UG82"	""	"Neutrophil degranulation; Antigen processing: Ubiquitination & Proteasome degradation"	"2"	"0"	"46.3"	"37.7"	"46.4"	"46.5"	"54.2"	"40.4"	"51.5"	"62.6"	"94.8"	"199.7"	"307.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35268"	"60S ribosomal protein L22 OS=Homo sapiens OX=9606 GN=RPL22 PE=1 SV=2"	"55"	"5"	"9"	"5"	"128"	"14.8"	"9.19"	"1421.03"	"21.59"	"4"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01776"	"6146"	"ENSG00000116251"	"RPL22"	"B2R495; hsa:6146; P35268; Q6IBD1"	"Cytoplasmic ribosomal proteins"	"SRP-dependent cotranslational protein targeting to membrane; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"348.4"	"311.8"	"322.3"	"314.0"	"336.3"	"382.1"	"433.7"	"400.0"	"479.7"	"409.0"	"423.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P41567"	"Eukaryotic translation initiation factor 1 OS=Homo sapiens OX=9606 GN=EIF1 PE=1 SV=1"	"25"	"3"	"10"	"1"	"113"	"12.7"	"7.44"	"2154.54"	"21.49"	"3"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf01253"	"10209"	"ENSG00000173812"	"EIF1"	"hsa:10209; P41567; Q9UNQ9"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	""	"2"	"3"	"117.7"	"123.7"	"116.8"	"115.5"	"129.0"	"124.9"	"183.6"	"354.8"	"1658.8"	"2248.5"	"2328.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05787"	"Keratin, type II cytoskeletal 8 OS=Homo sapiens OX=9606 GN=KRT8 PE=1 SV=7"	"13"	"8"	"14"	"1"	"483"	"53.7"	"5.59"	"2501.78"	"21.39"	"7"	"7"	"cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00038, Pf16208"	"3856"	"ENSG00000170421"	"KRT8"	"A8K4H3; B0AZN5; F8VXB4; hsa:3856; P05787; Q14099; Q14716; Q14717; Q53GJ0; Q6DHW5; Q6GMY0; Q6P4C7; Q96J60"	"Primary focal segmental glomerulosclerosis (FSGS); Acute viral myocarditis"	"Formation of the cornified envelope"	"4"	"0"	"24.5"	"27.1"	"30.8"	"28.7"	"32.3"	"38.3"	"39.1"	"46.5"	"86.4"	"147.9"	"180.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2Z4"	"Tyrosine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=YARS2 PE=1 SV=2"	"16"	"5"	"12"	"5"	"477"	"53.2"	"8.98"	"2466.63"	"21.38"	"5"	"5"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00579"	"51067"	"ENSG00000139131"	"YARS2"	"D3DUW8; hsa:51067; Q9H817; Q9Y2Z4"	"Orexin receptor pathway"	"Mitochondrial tRNA aminoacylation"	"2"	"0"	"90.4"	"79.7"	"91.1"	"88.2"	"86.3"	"90.0"	"103.9"	"139.2"	"256.3"	"377.8"	"657.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00151"	"PDZ and LIM domain protein 1 OS=Homo sapiens OX=9606 GN=PDLIM1 PE=1 SV=4"	"28"	"6"	"9"	"6"	"329"	"36.0"	"7.02"	"995.77"	"21.25"	"3"	"6"	"cell organization and biogenesis;stress response;developmental processes;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412, Pf00595, Pf15936"	"9124"	"ENSG00000107438"	"PDLIM1"	"B2RBS6; hsa:9124; O00151; Q5VZH5; Q9BPZ9"	""	""	"0"	"0"	"123.0"	"120.4"	"158.1"	"144.7"	"159.9"	"153.0"	"160.6"	"196.1"	"359.2"	"919.4"	"2118.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95208"	"Epsin-2 OS=Homo sapiens OX=9606 GN=EPN2 PE=1 SV=3"	"10"	"6"	"12"	"6"	"641"	"68.4"	"7.52"	"2126.11"	"21.14"	"6"	"6"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01417"	"22905"	"ENSG00000072134"	"EPN2"	"A8MTV8; B3KRX8; E9PBC2; hsa:22905; O95207; O95208; Q52LD0; Q9H7Z2; Q9UPT7"	""	"Cargo recognition for clathrin-mediated endocytosis"	"2"	"0"	"115.2"	"136.0"	"259.4"	"310.1"	"444.5"	"472.6"	"511.5"	"567.0"	"853.6"	"1049.5"	"1243.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6L8Q7"	"2',5'-phosphodiesterase 12 OS=Homo sapiens OX=9606 GN=PDE12 PE=1 SV=2"	"11"	"6"	"12"	"6"	"609"	"67.3"	"6.57"	"2195.29"	"21.12"	"6"	"6"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf03372"	"201626"	"ENSG00000174840"	"PDE12"	"B4DTU8; hsa:201626; Q6L8Q7; Q8IYU3; Q8NDU2; Q8TE78"	"Phosphodiesterases in neuronal function"	"OAS antiviral response"	"2"	"0"	"238.4"	"209.8"	"255.0"	"207.7"	"241.5"	"256.6"	"319.0"	"442.0"	"1311.0"	"2902.4"	"4703.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96GQ7"	"Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2"	"10"	"7"	"13"	"7"	"796"	"89.8"	"9.28"	"2285.72"	"21.09"	"6"	"7"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271"	"55661"	""	"DDX27"	"A0AVB6; B7ZLY1; hsa:55661; Q5VXM7; Q8WYG4; Q969N7; Q96F57; Q96GQ7; Q96L97; Q9BWY9; Q9BXF0; Q9H990; Q9NWU3; Q9P0C2; Q9UGD6"	""	""	"0"	"0"	"127.7"	"108.3"	"143.1"	"133.6"	"142.0"	"135.7"	"146.8"	"182.8"	"303.1"	"590.1"	"802.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25398"	"40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3"	"36"	"6"	"9"	"6"	"132"	"14.5"	"7.21"	"1453.91"	"21.04"	"4"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01248"	"6206"	"ENSG00000112306"	"RPS12"	"hsa:6206; P25398; Q76M58"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"507.0"	"482.7"	"522.0"	"451.7"	"510.0"	"403.8"	"622.2"	"767.1"	"1159.1"	"2481.1"	"5280.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95292"	"Vesicle-associated membrane protein-associated protein B/C OS=Homo sapiens OX=9606 GN=VAPB PE=1 SV=3"	"16"	"4"	"9"	"3"	"243"	"27.2"	"7.30"	"1842.20"	"21.02"	"3"	"4"	"cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00635"	"9217"	"ENSG00000124164"	"VAPB"	"A2A2F2; hsa:9217; O95292; O95293; Q9P0H0"	"Ciliary landscape"	"RHOC GTPase cycle; RHOA GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RHOD GTPase cycle; Sphingolipid de novo biosynthesis"	"7"	"0"	"66.0"	"51.5"	"69.4"	"68.2"	"90.8"	"66.6"	"96.6"	"163.2"	"700.0"	"1572.6"	"2579.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TAQ2"	"SWI/SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1"	"7"	"6"	"10"	"5"	"1214"	"132.8"	"5.69"	"1793.95"	"21.02"	"5"	"5"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00249, Pf04433, Pf16495, Pf16496, Pf16498"	"6601"	"ENSG00000139613"	"SMARCC2"	"F8VTJ5; hsa:6601; Q59GV3; Q8TAQ2; Q92923; Q96E12; Q96GY4"	"Androgen receptor network in prostate cancer; Tumor suppressor activity of SMARCB1; Thermogenesis; Kleefstra syndrome; 10q11.21q11.23 copy number variation syndrome"	"RMTs methylate histone arginines; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"	"7"	"0"	"427.2"	"359.0"	"341.7"	"319.9"	"383.6"	"394.3"	"476.7"	"590.0"	"953.7"	"1943.4"	"2893.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P2E9"	"Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5"	"18"	"9"	"15"	"8"	"1410"	"152.4"	"8.60"	"3565.95"	"20.93"	"9"	"6"	"protein metabolism;other metabolic processes;transport"	"other membranes;ER/Golgi;translational apparatus"	"other molecular function"	"Pf05104"	"6238"	"ENSG00000125844"	"RRBP1"	"A0A0A0MRV0; A2A2S6; A6NCN6; hsa:6238; O75300; O75301; Q5W165; Q96SB2; Q9BWP1; Q9H476; Q9P2E9"	"Ectoderm differentiation"	"Signaling by ALK fusions and activated point mutants"	"2"	"0"	"775.0"	"716.6"	"792.0"	"673.9"	"766.0"	"806.0"	"977.0"	"1053.0"	"1713.0"	"2547.9"	"3303.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04637"	"Cellular tumor antigen p53 OS=Homo sapiens OX=9606 GN=TP53 PE=1 SV=4"	"15"	"6"	"13"	"6"	"393"	"43.6"	"6.79"	"2618.12"	"20.87"	"6"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00870, Pf07710, Pf08563, Pf18521"	"7157"	"ENSG00000141510"	"TP53"	"hsa:7157; P04637; Q15086; Q15087; Q15088; Q16535; Q16807; Q16808; Q16809; Q16810; Q16811; Q16848; Q2XN98; Q3LRW1; Q3LRW2; Q3LRW3; Q3LRW4; Q3LRW5; Q86UG1; Q8J016; Q99659; Q9BTM4; Q9HAQ8; Q9NP68; Q9NPJ2; Q9NZD0; Q9UBI2; Q9UQ61"	"AMP-activated protein kinase signaling; miRNA regulation of DNA damage response; miRNAs involved in DNA damage response; Fluoropyrimidine activity; TP53 network; Folate metabolism; Apoptosis modulation and signaling; Cell cycle; Metastatic brain tumor; Glioblastoma signaling pathways; Gastric cancer network 2; Oncostatin M signaling pathway; Spinal cord injury; Retinoblastoma gene in cancer; Amyotrophic lateral sclerosis (ALS); ATM signaling pathway; Apoptosis; Mammary gland development pathway - Involution (Stage 4 of 4); Bladder cancer; Copper homeostasis; RAC1/PAK1/p38/MMP2 pathway; Photodynamic therapy-induced HIF-1 survival signaling; Hepatitis C and hepatocellular carcinoma; Pathways affected in adenoid cystic carcinoma; lncRNA-mediated mechanisms of therapeutic resistance; MAPK signaling pathway; miRNA regulation of p53 pathway in prostate cancer; Wnt signaling pathway and pluripotency; Endometrial cancer; PI3K-Akt signaling pathway; Caloric restriction and aging; Chromosomal and microsatellite instability in colorectal cancer ; Epithelial to mesenchymal transition in colorectal cancer; Non-small cell lung cancer; Breast cancer pathway; Pancreatic adenocarcinoma pathway; Ultraconserved region 339 modulation of tumor suppressor microRNAs in cancer; Ferroptosis; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; MicroRNA network associated with chronic lymphocytic leukemia; G1 to S cell cycle control; Measles virus infection; 22q11.2 copy number variation syndrome; Small cell lung cancer; Head and neck squamous cell carcinoma; Melanoma; Thyroid hormones production and peripheral downstream signaling effects; Netrin-UNC5B signaling pathway; IL-18 signaling pathway; Unfolded protein response; 16p11.2 proximal deletion syndrome; Pentose phosphate pathway in senescent cells; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Glycolysis in senescence; TCA cycle in senescence; Pleural mesothelioma; Lipid metabolism in senescent cells; DYRK1A involvement regarding cell proliferation in brain development; 2q37 copy number variation syndrome; Autophagy in pancreatic ductal adenocarcinoma; 11p11.2 copy number variation syndrome ; A network map of Macrophage-stimulating protein (MSP) signaling; ErbB signaling pathway; DNA damage response; DNA damage response (only ATM dependent)"	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; TP53 Regulates Transcription of DNA Repair Genes; Regulation of PTEN gene transcription; Factors involved in megakaryocyte development and platelet production; TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest; Autodegradation of the E3 ubiquitin ligase COP1; Ub-specific processing proteases; The role of GTSE1 in G2/M progression after G2 checkpoint; TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain; Regulation of TP53 Degradation; TP53 Regulates Transcription of Death Receptors and Ligands; Oxidative Stress Induced Senescence; Regulation of TP53 Activity through Phosphorylation; TP53 Regulates Metabolic Genes; Association of TriC/CCT with target proteins during biosynthesis; Interleukin-4 and Interleukin-13 signaling; Pre-NOTCH Transcription and Translation; Oncogene Induced Senescence; Transcriptional Regulation by VENTX; TP53 Regulates Transcription of Caspase Activators and Caspases; Regulation of TP53 Activity through Methylation; G2/M DNA damage checkpoint; Regulation of NF-kappa B signaling; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Activation of PUMA and translocation to mitochondria; TP53 Regulates Transcription of Genes Involved in Cytochrome C Release; TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain; Regulation of TP53 Activity through Association with Co-factors; Ovarian tumor domain proteases; Pyroptosis; SUMOylation of transcription factors; Regulation of TP53 Expression; RUNX3 regulates CDKN1A transcription; Activation of NOXA and translocation to mitochondria; Formation of Senescence-Associated Heterochromatin Foci (SAHF); PI5P Regulates TP53 Acetylation; Transcriptional  activation of  cell cycle inhibitor p21 ; Loss of function of TP53 in cancer due to loss of tetramerization ability"	"107"	"0"	"689.4"	"688.6"	"708.1"	"641.0"	"724.9"	"737.1"	"865.6"	"1089.6"	"1527.2"	"2996.8"	"4917.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NQW7"	"Xaa-Pro aminopeptidase 1 OS=Homo sapiens OX=9606 GN=XPNPEP1 PE=1 SV=3"	"11"	"5"	"9"	"5"	"623"	"69.9"	"5.67"	"1745.08"	"20.85"	"4"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00557, Pf01321, Pf16188, Pf16189"	"7511"	"ENSG00000108039"	"XPNPEP1"	"A8K071; G5E9Y2; G8JLB2; hsa:7511; O15250; Q53EX6; Q8N3Q0; Q96D23; Q9NQW7"	""	""	"0"	"0"	"57.0"	"41.4"	"73.0"	"62.5"	"70.7"	"58.5"	"99.4"	"152.5"	"373.4"	"1129.3"	"2589.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P16989"	"Y-box-binding protein 3 OS=Homo sapiens OX=9606 GN=YBX3 PE=1 SV=4"	"18"	"5"	"9"	"4"	"372"	"40.1"	"9.77"	"1250.45"	"20.81"	"4"	"5"	"stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00313"	"8531"	"ENSG00000060138"	"YBX3"	"B2RBW6; hsa:8531; P16989; Q14121; Q969N6; Q96B76"	"RalA downstream regulated genes; Apoptosis-related network due to altered Notch3 in ovarian cancer"	""	"2"	"0"	"228.3"	"156.1"	"254.5"	"237.6"	"251.6"	"238.6"	"274.8"	"280.5"	"475.1"	"706.6"	"947.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16658"	"Fascin OS=Homo sapiens OX=9606 GN=FSCN1 PE=1 SV=3"	"10"	"4"	"8"	"4"	"493"	"54.5"	"7.24"	"1451.98"	"20.79"	"2"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf06268"	"6624"	"ENSG00000075618"	"FSCN1"	"A6NI89; B2RE97; hsa:6624; Q16658; Q96IC5; Q96IH1; Q9BRF1"	"VEGFA-VEGFR2 signaling; Urotensin-II-mediated signaling pathway"	"Interleukin-4 and Interleukin-13 signaling"	"3"	"0"	"50.4"	"53.8"	"63.7"	"46.6"	"64.9"	"56.4"	"75.7"	"99.4"	"178.3"	"869.1"	"2859.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13595"	"Transformer-2 protein homolog alpha OS=Homo sapiens OX=9606 GN=TRA2A PE=1 SV=1"	"17"	"6"	"13"	"6"	"282"	"32.7"	"11.27"	"1889.84"	"20.74"	"4"	"6"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf00076"	"29896"	"ENSG00000164548"	"TRA2A"	"B4DQI6; B4DUA9; E9PD75; hsa:29896; Q13595"	"Orexin receptor pathway"	""	"1"	"0"	"759.8"	"849.7"	"619.7"	"599.6"	"647.5"	"641.4"	"851.0"	"1094.7"	"1431.7"	"2025.6"	"3175.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15381"	"Nuclear valosin-containing protein-like OS=Homo sapiens OX=9606 GN=NVL PE=1 SV=1"	"9"	"6"	"10"	"6"	"856"	"95.0"	"6.48"	"2423.05"	"20.67"	"5"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00004, Pf16725, Pf17862"	"4931"	"ENSG00000143748"	"NVL"	"B4DMC4; B4DP98; hsa:4931; O15381; Q96EM7"	""	""	"0"	"0"	"163.4"	"141.8"	"186.6"	"173.9"	"187.3"	"171.9"	"205.0"	"239.0"	"595.4"	"1097.6"	"1439.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62249"	"40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2"	"34"	"6"	"15"	"6"	"146"	"16.4"	"10.21"	"2901.35"	"20.64"	"6"	"6"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00380"	"6217"	"ENSG00000105193"	"RPS16"	"B2RDD5; hsa:6217; P17008; P62249"	"Cytoplasmic ribosomal proteins"	"Major pathway of rRNA processing in the nucleolus and cytosol; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"685.0"	"747.5"	"674.1"	"652.2"	"734.5"	"733.6"	"845.5"	"990.5"	"1432.7"	"2345.0"	"3114.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95071"	"E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2"	"3"	"9"	"14"	"9"	"2799"	"309.2"	"5.85"	"2111.84"	"20.62"	"7"	"7"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00632, Pf00658, Pf11547"	"51366"	"ENSG00000104517"	"UBR5"	"B2RP24; hsa:51366; J3KMW7; O94970; O95071; Q9NPL3"	"Mesodermal commitment pathway"	""	"1"	"0"	"650.2"	"550.3"	"650.6"	"511.7"	"576.6"	"624.8"	"770.0"	"1038.0"	"1519.7"	"2407.6"	"3585.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49915"	"GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1"	"9"	"4"	"7"	"4"	"693"	"76.7"	"6.87"	"987.47"	"20.60"	"1"	"4"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf00117, Pf00958, Pf02540"	"8833"	"ENSG00000163655"	"GMPS"	"A8K639; B4DXV7; F8W720; hsa:8833; P49915"	""	"Purine ribonucleoside monophosphate biosynthesis; Azathioprine ADME"	"2"	"0"	"36.0"	"35.7"	"47.8"	"38.9"	"47.0"	"31.7"	"46.3"	"83.9"	"184.2"	"694.2"	"1830.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4L1"	"Hypoxia up-regulated protein 1 OS=Homo sapiens OX=9606 GN=HYOU1 PE=1 SV=1"	"8"	"5"	"6"	"5"	"999"	"111.3"	"5.22"	"342.60"	"20.58"	"1"	"5"	"protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"non-structural extracellular;ER/Golgi;other cell component"	"other molecular function"	"Pf00012"	"10525"	"ENSG00000149428; ENSG00000280682"	"HYOU1"	"A8C1Z0; B7Z909; hsa:10525; Q2I204; Q53H25; Q9Y4L1"	"VEGFA-VEGFR2 signaling"	"XBP1(S) activates chaperone genes; Scavenging by Class F Receptors"	"3"	"0"	"106.2"	"90.0"	"129.0"	"121.1"	"117.3"	"105.5"	"133.1"	"183.8"	"323.5"	"981.5"	"1897.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75179"	"Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3"	"2"	"5"	"11"	"2"	"2603"	"274.1"	"6.52"	"2129.44"	"20.54"	"4"	"5"	"stress response;developmental processes;other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf00013, Pf12796"	"26057"	"ENSG00000132466"	"ANKRD17"	"E7EUV3; G5E964; hsa:26057; O75179; Q6PJ85; Q6PK85; Q6PKA2; Q86XI3; Q8NDR5; Q96I86; Q9H288; Q9H6J9"	""	""	"0"	"3"	"171.8"	"156.6"	"182.0"	"156.2"	"182.4"	"175.1"	"222.0"	"279.9"	"405.7"	"627.6"	"835.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IWX8"	"Calcium homeostasis endoplasmic reticulum protein OS=Homo sapiens OX=9606 GN=CHERP PE=1 SV=3"	"9"	"7"	"10"	"7"	"916"	"103.6"	"9.04"	"1136.31"	"20.50"	"4"	"6"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf01585, Pf01805, Pf04818"	"10523"	"ENSG00000085872"	"CHERP"	"hsa:10523; O00302; Q4G0Y5; Q8IWX8; Q8WU30; Q99492"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"550.5"	"497.6"	"581.0"	"530.3"	"556.8"	"568.8"	"648.8"	"718.5"	"969.3"	"1867.7"	"2952.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7L7X3"	"Serine/threonine-protein kinase TAO1 OS=Homo sapiens OX=9606 GN=TAOK1 PE=1 SV=1"	"7"	"6"	"11"	"5"	"1001"	"116.0"	"7.65"	"2567.02"	"20.49"	"6"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;cytoskeletal activity;kinase activity;other molecular function"	"Pf00069"	"57551"	"ENSG00000160551"	"TAOK1"	"A2RUT8; B7ZLV6; hsa:57551; Q7L7X3; Q96L75; Q9H2K7; Q9H7S5; Q9P2I6"	"Microtubule cytoskeleton regulation; MAPK signaling pathway"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"8"	"1"	"164.5"	"136.9"	"170.0"	"157.1"	"178.5"	"211.6"	"252.4"	"390.1"	"618.1"	"1107.3"	"1342.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92621"	"Nuclear pore complex protein Nup205 OS=Homo sapiens OX=9606 GN=NUP205 PE=1 SV=3"	"4"	"7"	"11"	"7"	"2012"	"227.8"	"6.19"	"1659.48"	"20.45"	"5"	"6"	"cell organization and biogenesis;transport"	"other membranes;cytosol;nucleus"	"other molecular function"	"Pf11894"	"23165"	"ENSG00000155561"	"NUP205"	"A6H8X3; hsa:23165; Q86YC1; Q92621"	""	"Rev-mediated nuclear export of HIV RNA; Nuclear import of Rev protein; Postmitotic nuclear pore complex (NPC) reformation; HCMV Late Events; HCMV Early Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"29"	"0"	"212.7"	"238.7"	"239.3"	"211.3"	"243.5"	"244.2"	"268.6"	"352.0"	"747.8"	"1521.2"	"2096.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99426"	"Tubulin-folding cofactor B OS=Homo sapiens OX=9606 GN=TBCB PE=1 SV=2"	"23"	"4"	"8"	"4"	"244"	"27.3"	"5.15"	"1362.15"	"20.45"	"2"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf01302, Pf14560"	"1155"	"ENSG00000105254"	"TBCB"	"hsa:1155; O00111; O00674; O14728; Q6FGY5; Q99426"	""	"Post-chaperonin tubulin folding pathway"	"1"	"0"	"34.2"	"39.5"	"52.3"	"42.0"	"49.5"	"44.8"	"58.6"	"84.2"	"152.3"	"789.2"	"2875.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00629"	"Importin subunit alpha-3 OS=Homo sapiens OX=9606 GN=KPNA4 PE=1 SV=1"	"11"	"3"	"5"	"2"	"521"	"57.9"	"4.96"	"661.25"	"20.43"	"1"	"3"	"cell-cell signaling;other metabolic processes;transport"	"other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00514, Pf01749, Pf16186"	"3840"	"ENSG00000186432"	"KPNA4"	"A8K4S6; D3DNM2; hsa:3840; O00190; O00629"	"Leptin signaling pathway"	"ISG15 antiviral mechanism; NS1 Mediated Effects on Host Pathways"	"3"	"0"	"25.5"	"30.6"	"37.0"	"38.4"	"32.0"	"30.5"	"41.7"	"63.5"	"115.6"	"291.2"	"495.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96SI9"	"Spermatid perinuclear RNA-binding protein OS=Homo sapiens OX=9606 GN=STRBP PE=1 SV=1"	"12"	"7"	"12"	"5"	"672"	"73.6"	"8.72"	"2570.62"	"20.42"	"6"	"6"	"other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity"	"Pf00035, Pf07528"	"55342"	"ENSG00000165209"	"STRBP"	"hsa:55342; Q32NB9; Q96SI9; Q9BUE1; Q9BXG4; Q9H0B4; Q9H7V1; Q9NUK4"	""	""	"0"	"0"	"457.0"	"463.5"	"478.6"	"401.7"	"514.2"	"494.6"	"595.7"	"695.4"	"1029.6"	"1984.3"	"3052.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NUU7"	"ATP-dependent RNA helicase DDX19A OS=Homo sapiens OX=9606 GN=DDX19A PE=1 SV=1"	"9"	"5"	"12"	"2"	"478"	"53.9"	"6.58"	"2318.24"	"20.42"	"5"	"5"	"other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"55308"	"ENSG00000168872"	"DDX19A"	"B2RPL0; B4DRZ7; hsa:55308; Q53FM0; Q9NUU7"	""	""	"0"	"3"	"350.6"	"257.1"	"391.5"	"347.0"	"331.6"	"355.5"	"438.8"	"536.3"	"897.0"	"1738.1"	"2542.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15145"	"Actin-related protein 2/3 complex subunit 3 OS=Homo sapiens OX=9606 GN=ARPC3 PE=1 SV=3"	"25"	"5"	"11"	"5"	"178"	"20.5"	"8.59"	"2376.37"	"20.39"	"4"	"5"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf04062"	"10094"	"ENSG00000111229"	"ARPC3"	"hsa:10094; O00554; O15145"	"Pathogenic Escherichia coli infection"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Clathrin-mediated endocytosis; EPHB-mediated forward signaling"	"6"	"0"	"249.4"	"203.4"	"307.6"	"247.5"	"276.2"	"249.2"	"348.1"	"497.0"	"1792.3"	"2543.4"	"3343.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P41250"	"Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3"	"10"	"5"	"7"	"4"	"739"	"83.1"	"7.03"	"668.07"	"20.39"	"2"	"5"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"non-structural extracellular;cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00458, Pf00587, Pf03129"	"2617"	"ENSG00000106105"	"GARS1"	"A0A090N8G0; B3KQA2; B4DIA0; hsa:2617; P41250; Q969Y1"	""	"Cytosolic tRNA aminoacylation; Mitochondrial tRNA aminoacylation"	"2"	"0"	"29.7"	"18.1"	"30.3"	"26.7"	"28.4"	"29.5"	"35.3"	"52.4"	"109.5"	"367.4"	"1043.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P80723"	"Brain acid soluble protein 1 OS=Homo sapiens OX=9606 GN=BASP1 PE=1 SV=2"	"40"	"6"	"8"	"6"	"227"	"22.7"	"4.63"	"1513.12"	"20.35"	"3"	"5"	"developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05466"	"10409"	"ENSG00000176788"	"BASP1"	"B4DJA8; D3DTD5; hsa:10409; O43596; P80723; Q5U0S0; Q9BWA5"	""	"RHOF GTPase cycle"	"1"	"0"	"253.1"	"275.3"	"262.1"	"262.3"	"272.6"	"273.2"	"315.6"	"378.3"	"815.4"	"2340.3"	"4482.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96NC0"	"Zinc finger matrin-type protein 2 OS=Homo sapiens OX=9606 GN=ZMAT2 PE=1 SV=1"	"30"	"7"	"16"	"7"	"199"	"23.6"	"9.01"	"2306.30"	"20.34"	"6"	"6"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf12171"	"153527"	"ENSG00000146007"	"ZMAT2"	"hsa:153527; Q96NC0"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"1586.1"	"1342.9"	"1566.5"	"1421.9"	"1541.9"	"1490.7"	"1790.8"	"2070.6"	"3351.5"	"4338.1"	"5094.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16795"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFA9 PE=1 SV=2"	"12"	"3"	"8"	"3"	"377"	"42.5"	"9.80"	"2085.57"	"20.28"	"3"	"3"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf01370"	"4704"	"ENSG00000139180"	"NDUFA9"	"hsa:4704; Q14076; Q16795; Q2NKX0"	"Electron transport chain: OXPHOS system in mitochondria; Ciliary landscape; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"6"	"0"	"81.1"	"77.9"	"98.1"	"88.6"	"101.2"	"92.8"	"114.9"	"168.1"	"418.0"	"785.5"	"1035.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92890"	"Ubiquitin recognition factor in ER-associated degradation protein 1 OS=Homo sapiens OX=9606 GN=UFD1 PE=1 SV=3"	"19"	"6"	"11"	"6"	"307"	"34.5"	"6.70"	"1656.01"	"20.25"	"5"	"6"	"protein metabolism;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf03152"	"7353"	"ENSG00000070010"	"UFD1"	"A8MW31; hsa:7353; Q92890; Q9Y5N0"	"22q11.2 copy number variation syndrome"	"Ub-specific processing proteases; Neddylation; KEAP1-NFE2L2 pathway; Translesion Synthesis by POLH"	"5"	"0"	"391.7"	"351.2"	"425.7"	"378.7"	"397.3"	"403.1"	"450.4"	"506.9"	"992.1"	"2488.6"	"3678.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14247"	"Src substrate cortactin OS=Homo sapiens OX=9606 GN=CTTN PE=1 SV=2"	"10"	"5"	"10"	"5"	"550"	"61.5"	"5.40"	"1468.53"	"20.12"	"3"	"5"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf02218, Pf14604"	"2017"	"ENSG00000085733; ENSG00000288401"	"CTTN"	"hsa:2017; Q14247; Q8N707; Q96H99"	"Pathogenic Escherichia coli infection; Hepatitis C and hepatocellular carcinoma"	"Clathrin-mediated endocytosis; RHO GTPases activate PAKs"	"4"	"0"	"352.9"	"353.6"	"347.5"	"368.3"	"376.0"	"404.0"	"444.0"	"515.8"	"1230.8"	"3801.8"	"6990.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NW64"	"Pre-mRNA-splicing factor RBM22 OS=Homo sapiens OX=9606 GN=RBM22 PE=1 SV=1"	"14"	"5"	"13"	"5"	"420"	"46.9"	"8.54"	"2976.03"	"20.07"	"5"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"55696"	"ENSG00000086589"	"RBM22"	"A6NDM5; B4DLI9; hsa:55696; O95607; Q9NW64"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"741.5"	"684.7"	"762.9"	"655.3"	"755.7"	"687.9"	"909.1"	"1144.5"	"1567.4"	"2472.8"	"3840.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q05048"	"Cleavage stimulation factor subunit 1 OS=Homo sapiens OX=9606 GN=CSTF1 PE=1 SV=1"	"17"	"6"	"9"	"6"	"431"	"48.3"	"6.58"	"1024.12"	"20.03"	"3"	"6"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf00400, Pf16699"	"1477"	"ENSG00000101138"	"CSTF1"	"hsa:1477; Q05048; Q5QPD8"	"mRNA processing"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"5"	"0"	"351.6"	"355.5"	"415.7"	"372.5"	"397.3"	"338.5"	"463.0"	"597.6"	"1133.9"	"2450.4"	"4292.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P43246"	"DNA mismatch repair protein Msh2 OS=Homo sapiens OX=9606 GN=MSH2 PE=1 SV=1"	"10"	"7"	"10"	"7"	"934"	"104.7"	"5.77"	"1341.32"	"20.01"	"4"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00488, Pf01624, Pf05188, Pf05190, Pf05192"	"4436"	"ENSG00000095002"	"MSH2"	"B4E2Z2; hsa:4436; O75488; P43246"	"RAC1/PAK1/p38/MMP2 pathway; Chromosomal and microsatellite instability in colorectal cancer ; Ciliary landscape; DNA repair pathways, full network; p53 transcriptional gene network; DNA mismatch repair"	"TP53 Regulates Transcription of DNA Repair Genes; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta); Defective Mismatch Repair Associated With MSH3; Defective Mismatch Repair Associated With MSH2; Defective Mismatch Repair Associated With MSH6"	"12"	"0"	"465.4"	"391.7"	"522.8"	"435.2"	"519.8"	"495.5"	"543.3"	"693.1"	"1469.3"	"2956.4"	"4688.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P15170"	"Eukaryotic peptide chain release factor GTP-binding subunit ERF3A OS=Homo sapiens OX=9606 GN=GSPT1 PE=1 SV=1"	"13"	"6"	"8"	"2"	"499"	"55.7"	"5.62"	"963.14"	"19.95"	"2"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03143, Pf03144"	"2935"	"ENSG00000103342"	"GSPT1"	"hsa:2935; J3KQG6; P15170; Q96GF2"	""	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"4"	"4"	"89.2"	"84.4"	"114.4"	"128.7"	"117.9"	"119.2"	"128.9"	"193.0"	"540.9"	"3726.6"	"5959.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15427"	"Splicing factor 3B subunit 4 OS=Homo sapiens OX=9606 GN=SF3B4 PE=1 SV=1"	"15"	"4"	"9"	"4"	"424"	"44.4"	"8.56"	"1455.46"	"19.95"	"3"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00076"	"10262"	"ENSG00000143368"	"SF3B4"	"hsa:10262; Q15427; Q5SZ63"	"mRNA processing; 10q22q23 copy number variation"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"4"	"0"	"397.8"	"393.5"	"417.4"	"357.4"	"415.4"	"431.3"	"478.5"	"545.9"	"647.4"	"1164.7"	"2014.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5T2T1"	"MAGUK p55 subfamily member 7 OS=Homo sapiens OX=9606 GN=MPP7 PE=1 SV=1"	"22"	"7"	"10"	"7"	"576"	"65.5"	"7.14"	"2174.59"	"19.91"	"5"	"5"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00018, Pf00595, Pf00625, Pf02828"	"143098"	"ENSG00000150054"	"MPP7"	"B2RCC9; B4DWL9; B5MDZ3; D3DRW3; hsa:143098; Q5T2T0; Q5T2T1; Q8IY28"	""	"RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOQ GTPase cycle; RHOG GTPase cycle; RHOJ GTPase cycle"	"6"	"0"	"187.0"	"170.3"	"195.6"	"167.0"	"190.9"	"211.9"	"235.1"	"339.3"	"1035.7"	"1331.9"	"1452.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99460"	"26S proteasome non-ATPase regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PSMD1 PE=1 SV=2"	"6"	"5"	"12"	"5"	"953"	"105.8"	"5.39"	"2351.33"	"19.90"	"5"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf01851, Pf13646, Pf18004"	"5707"	"ENSG00000173692"	"PSMD1"	"B8ZZH9; hsa:5707; Q24JU0; Q53TI2; Q6GMU5; Q6P2P4; Q6PJM7; Q6PKG9; Q86VU1; Q8IV79; Q99460"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A; MAPK6/MAPK4 signaling; The role of GTSE1 in G2/M progression after G2 checkpoint; Neutrophil degranulation; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"64"	"0"	"424.2"	"311.0"	"455.7"	"428.9"	"462.5"	"432.9"	"487.8"	"569.3"	"809.6"	"1388.3"	"2658.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55036"	"26S proteasome non-ATPase regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMD4 PE=1 SV=1"	"18"	"4"	"7"	"4"	"377"	"40.7"	"4.79"	"1278.49"	"19.90"	"3"	"4"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf02809, Pf13519"	"5710"	"ENSG00000159352"	"PSMD4"	"D3DV16; hsa:5710; P55036; Q5VWC5; Q9NS92"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; VEGFA-VEGFR2 signaling; Alzheimer's disease"	"Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Regulation of expression of SLITs and ROBOs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"64"	"0"	"109.5"	"100.5"	"109.0"	"101.4"	"130.4"	"125.4"	"133.4"	"147.2"	"415.1"	"2036.5"	"2893.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P0L0"	"Vesicle-associated membrane protein-associated protein A OS=Homo sapiens OX=9606 GN=VAPA PE=1 SV=3"	"26"	"5"	"10"	"4"	"249"	"27.9"	"8.62"	"2059.71"	"19.90"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00635"	"9218"	"ENSG00000101558"	"VAPA"	"A6NDZ0; D3DUI3; hsa:9218; O75453; Q5U0E7; Q9P0L0; Q9UBZ2"	"Exercise-induced circadian regulation; Cholesterol metabolism"	"Neutrophil degranulation; Insertion of tail-anchored proteins into the endoplasmic reticulum membrane; Sphingolipid de novo biosynthesis"	"5"	"1"	"222.3"	"202.2"	"226.9"	"206.8"	"243.6"	"232.5"	"294.5"	"382.8"	"1214.2"	"2262.4"	"3412.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08579"	"U2 small nuclear ribonucleoprotein B'' OS=Homo sapiens OX=9606 GN=SNRPB2 PE=1 SV=1"	"15"	"4"	"14"	"2"	"225"	"25.5"	"9.72"	"2204.00"	"19.88"	"4"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6629"	"ENSG00000125870"	"SNRPB2"	"B2R7J3; D3DW21; hsa:6629; P08579; Q9UJD4"	"mRNA processing; Ciliary landscape"	"mRNA Splicing - Major Pathway"	"3"	"0"	"293.6"	"166.2"	"254.3"	"275.8"	"268.9"	"257.8"	"286.7"	"321.9"	"379.6"	"521.9"	"871.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q0VDF9"	"Heat shock 70 kDa protein 14 OS=Homo sapiens OX=9606 GN=HSPA14 PE=1 SV=1"	"12"	"4"	"8"	"4"	"509"	"54.8"	"5.59"	"1379.52"	"19.77"	"2"	"4"	"protein metabolism;other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00012"	"51182"	"ENSG00000187522"	"HSPA14"	"A8K8F8; B0YIY9; hsa:51182; Q0VDF9; Q9P0X2; Q9UI07"	"Parkin-ubiquitin proteasomal system pathway"	"Regulation of HSF1-mediated heat shock response"	"2"	"0"	"53.0"	"52.6"	"64.6"	"60.2"	"73.3"	"66.8"	"78.6"	"116.2"	"360.7"	"815.6"	"1061.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BY77"	"Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2"	"16"	"4"	"7"	"4"	"421"	"46.1"	"9.99"	"1538.84"	"19.73"	"3"	"4"	"other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"84271"	"ENSG00000100227"	"POLDIP3"	"A8K6F8; A8K6V9; hsa:84271; Q009A7; Q5H972; Q6PGN6; Q7Z6Z0; Q9BY77; Q9NSP5; Q9NSP6"	""	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript"	"3"	"0"	"164.3"	"184.3"	"205.2"	"184.6"	"188.7"	"171.4"	"222.7"	"253.5"	"365.3"	"676.9"	"911.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A6NHR9"	"Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2"	"3"	"5"	"9"	"5"	"2005"	"226.2"	"7.30"	"1854.02"	"19.69"	"4"	"5"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06470, Pf13589"	"23347"	"ENSG00000101596"	"SMCHD1"	"A6NHR9; hsa:23347; O75141; Q6AHX6; Q6ZTQ8; Q9H6Q2; Q9UG39"	""	""	"0"	"0"	"337.3"	"284.2"	"367.4"	"337.2"	"375.9"	"304.7"	"425.9"	"563.9"	"809.7"	"1631.1"	"1868.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01085"	"Nucleolysin TIAR OS=Homo sapiens OX=9606 GN=TIAL1 PE=1 SV=1"	"14"	"6"	"14"	"4"	"375"	"41.6"	"7.74"	"2724.71"	"19.66"	"6"	"5"	"cell cycle OR cell proliferation;stress response;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"7073"	"ENSG00000151923"	"TIAL1"	"A8K3T0; A8K4L9; hsa:7073; Q01085"	""	"FGFR2 alternative splicing"	"1"	"1"	"792.4"	"648.5"	"824.6"	"734.9"	"876.6"	"751.4"	"901.1"	"1031.0"	"1283.2"	"1754.4"	"2415.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5T9A4"	"ATPase family AAA domain-containing protein 3B OS=Homo sapiens OX=9606 GN=ATAD3B PE=1 SV=1"	"8"	"5"	"9"	"3"	"648"	"72.5"	"9.20"	"1523.88"	"19.62"	"4"	"5"	"cell organization and biogenesis"	"plasma membrane;other membranes;mitochondrion"	"other molecular function"	"Pf00004, Pf12037"	"83858"	"ENSG00000160072"	"ATAD3B"	"A8K3H1; hsa:83858; Q5T9A4; Q6ZRB5; Q9BUK4; Q9ULE7"	"1p36 copy number variation syndrome"	"Neutrophil degranulation"	"2"	"2"	"249.1"	"274.0"	"233.8"	"203.1"	"264.1"	"241.9"	"288.9"	"363.5"	"583.3"	"1114.8"	"1858.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99623"	"Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2"	"20"	"6"	"14"	"6"	"299"	"33.3"	"9.83"	"2684.54"	"19.61"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01145"	"11331"	"ENSG00000215021"	"PHB2"	"B4DP75; hsa:11331; Q2YDA4; Q7KYU3; Q92978; Q99623"	""	"Processing of SMDT1"	"1"	"0"	"812.7"	"804.4"	"720.3"	"685.9"	"786.5"	"835.6"	"921.4"	"1065.6"	"1656.2"	"2908.9"	"3836.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13995"	"Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD2 PE=1 SV=2"	"19"	"6"	"9"	"6"	"350"	"37.9"	"8.73"	"1261.07"	"19.59"	"3"	"5"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00763, Pf02882"	"10797"	"ENSG00000065911"	"MTHFD2"	"hsa:10797; P13995; Q53G90; Q53GV5; Q53S36; Q7Z650"	"Folate metabolism; One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways"	"Metabolism of folate and pterines"	"4"	"0"	"375.1"	"384.6"	"381.6"	"345.6"	"438.5"	"414.6"	"467.0"	"622.5"	"1525.7"	"3293.6"	"4499.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04843"	"Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1"	"9"	"5"	"11"	"5"	"607"	"68.5"	"6.38"	"1807.23"	"19.59"	"4"	"5"	"protein metabolism;other metabolic processes"	"other membranes;cytosol;ER/Golgi;other cell component"	""	"Pf04597"	"6184"	"ENSG00000163902"	"RPN1"	"B2R5Z0; D3DNB6; hsa:6184; P04843; Q68DT1"	"Proteasome degradation; N-glycan biosynthesis"	"SRP-dependent cotranslational protein targeting to membrane; Asparagine N-linked glycosylation; Maturation of spike protein"	"5"	"0"	"226.0"	"222.6"	"278.6"	"227.7"	"267.3"	"272.1"	"300.9"	"388.7"	"903.1"	"2210.2"	"3337.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14974"	"Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2"	"6"	"5"	"10"	"5"	"876"	"97.1"	"4.78"	"1953.68"	"19.59"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;signal transduction;other biological processes"	"non-structural extracellular;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00514, Pf03810"	"3837"	"ENSG00000108424"	"KPNB1"	"B7ZAV6; D3DTT3; hsa:3837; Q14637; Q14974; Q53XN2; Q96J27"	"Sterol regulatory element-binding proteins (SREBP) signaling; 22q11.2 copy number variation syndrome"	"Neutrophil degranulation; Assembly of the ORC complex at the origin of replication; Apoptosis induced DNA fragmentation; ISG15 antiviral mechanism; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Nuclear import of Rev protein; Interferon alpha/beta signaling; Regulation of cholesterol biosynthesis by SREBP (SREBF); SARS-CoV-1 activates/modulates innate immune responses; Initiation of Nuclear Envelope (NE) Reformation; Postmitotic nuclear pore complex (NPC) reformation; Inhibition of nitric oxide production"	"15"	"0"	"274.3"	"263.0"	"302.4"	"287.9"	"293.7"	"316.7"	"377.6"	"475.0"	"925.3"	"2282.3"	"3615.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62140"	"Serine/threonine-protein phosphatase PP1-beta catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CB PE=1 SV=3"	"21"	"5"	"9"	"1"	"327"	"37.2"	"6.19"	"1599.85"	"19.57"	"4"	"5"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00149, Pf16891"	"5500"	"ENSG00000213639"	"PPP1CB"	"B2R5V4; D6W565; hsa:5500; P37140; P62140; Q5U087; Q6FG45"	"Common pathways underlying drug addiction; Focal adhesion; Hippo-Merlin signaling dysregulation; 22q11.2 copy number variation syndrome; Airway smooth muscle cell contraction; Neuroinflammation and glutamatergic signaling; G13 signaling pathway"	"Circadian Clock; RHO GTPases activate CIT; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; Triglyceride catabolism; Regulation of PLK1 Activity at G2/M Transition; RAF activation; SHOC2 M1731 mutant abolishes MRAS complex function; Gain-of-function MRAS complexes activate RAF signaling; RHO GTPases activate PAKs; Downregulation of TGF-beta receptor signaling"	"18"	"0"	"48.3"	"40.7"	"41.7"	"47.5"	"55.7"	"45.3"	"51.9"	"71.4"	"170.5"	"418.1"	"593.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9C0C2"	"182 kDa tankyrase-1-binding protein OS=Homo sapiens OX=9606 GN=TNKS1BP1 PE=1 SV=4"	"4"	"6"	"12"	"6"	"1729"	"181.7"	"4.86"	"1915.48"	"19.48"	"6"	"6"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf15327"	"85456"	"ENSG00000149115"	"TNKS1BP1"	"A7E2F8; hsa:85456; Q6PJ35; Q6ZV74; Q9C0C2"	"Ciliary landscape"	"Deadenylation of mRNA; TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"	"3"	"0"	"250.8"	"239.6"	"276.9"	"221.5"	"266.5"	"274.2"	"314.6"	"381.5"	"615.3"	"1042.1"	"1368.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P0DP25"	"Calmodulin-3 OS=Homo sapiens OX=9606 GN=CALM3 PE=1 SV=1"	"21"	"5"	"10"	"5"	"149"	"16.8"	"4.22"	"2334.59"	"19.40"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;mitochondrion;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf13499"	"801; 805; 808"	"ENSG00000160014"	"CALM3"	"hsa:801; hsa:805; hsa:808; P02593; P0DP25; P62158; P70667; P99014; Q13942; Q53S29; Q61379; Q61380; Q96HK3"	"Physiological and pathological hypertrophy of the heart; MicroRNAs in cardiomyocyte hypertrophy; Alzheimer's disease and miRNA effects; T cell receptor and co-stimulatory signaling; Cardiac hypertrophic response; Myometrial relaxation and contraction pathways; G protein signaling pathways; Ras signaling; Melanoma; Endochondral ossification; Endochondral ossification with skeletal dysplasias; CAMKK2 pathway; Glycogen synthesis and degradation; Neuroinflammation and glutamatergic signaling; Alzheimer's disease; G13 signaling pathway; Calcium regulation in cardiac cells"	""	"17"	"0"	"795.7"	"677.0"	"868.6"	"698.0"	"750.6"	"886.9"	"1114.4"	"1346.6"	"2749.4"	"3556.1"	"4674.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99567"	"Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2"	"10"	"5"	"10"	"5"	"741"	"83.5"	"5.69"	"1947.92"	"19.38"	"5"	"5"	"cell cycle OR cell proliferation;other metabolic processes;transport"	"cytosol;nucleus"	"other molecular function"	"Pf10168"	"4927"	"ENSG00000108559"	"NUP88"	"D3DTM2; hsa:4927; Q99567; Q9BWE5"	"Ciliary landscape"	"HCMV Early Events; ISG15 antiviral mechanism; tRNA processing in the nucleus; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; HCMV Late Events; Regulation of HSF1-mediated heat shock response; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; Nuclear Pore Complex (NPC) Disassembly; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"29"	"0"	"258.7"	"295.4"	"277.0"	"237.6"	"248.2"	"254.1"	"328.7"	"447.4"	"743.9"	"1410.2"	"2120.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86W42"	"THO complex subunit 6 homolog OS=Homo sapiens OX=9606 GN=THOC6 PE=1 SV=1"	"20"	"5"	"9"	"5"	"341"	"37.5"	"7.43"	"2076.63"	"19.37"	"4"	"5"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00400"	"79228"	"ENSG00000131652"	"THOC6"	"B2RA85; hsa:79228; Q86W42; Q8NBR1; Q9BTV9"	""	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript"	"3"	"0"	"260.1"	"271.0"	"262.9"	"238.1"	"259.7"	"247.7"	"323.1"	"460.7"	"692.4"	"1061.8"	"1633.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60739"	"Eukaryotic translation initiation factor 1b OS=Homo sapiens OX=9606 GN=EIF1B PE=1 SV=2"	"29"	"3"	"8"	"1"	"113"	"12.8"	"7.37"	"1889.77"	"19.36"	"3"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"translational apparatus"	"translation activity;nucleic acid binding activity"	"Pf01253"	"10289"	"ENSG00000114784"	"EIF1B"	"hsa:10289; O60739; Q9UQF8"	""	""	"0"	"0"	"20.1"	"11.6"	"30.8"	"24.5"	"20.5"	"21.5"	"38.0"	"63.1"	"301.8"	"276.1"	"314.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62269"	"40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3"	"33"	"6"	"15"	"6"	"152"	"17.7"	"10.99"	"3429.95"	"19.32"	"6"	"4"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00416"	"6222"	"ENSG00000096150; ENSG00000223367; ENSG00000226225; ENSG00000231500; ENSG00000235650"	"RPS18"	"hsa:6222; P25232; P62269; Q5SUJ3; Q6IPF8"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"634.9"	"625.1"	"675.1"	"545.4"	"620.5"	"646.3"	"813.4"	"1099.0"	"1564.0"	"2708.6"	"4043.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15344"	"E3 ubiquitin-protein ligase Midline-1 OS=Homo sapiens OX=9606 GN=MID1 PE=1 SV=1"	"10"	"5"	"8"	"5"	"667"	"75.2"	"6.80"	"1191.87"	"19.31"	"3"	"5"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00041, Pf00622, Pf00643, Pf13445, Pf13765, Pf18568"	"4281"	"ENSG00000101871"	"MID1"	"B2RCG2; hsa:4281; O15344; O75361; Q9BZX5"	""	"Interferon gamma signaling"	"1"	"0"	"192.6"	"150.5"	"228.3"	"219.5"	"232.6"	"275.3"	"400.2"	"707.8"	"1280.3"	"1420.0"	"1416.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13243"	"Serine/arginine-rich splicing factor 5 OS=Homo sapiens OX=9606 GN=SRSF5 PE=1 SV=1"	"17"	"5"	"8"	"4"	"272"	"31.2"	"11.59"	"842.54"	"19.31"	"3"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00076"	"6430"	"ENSG00000100650"	"SRSF5"	"hsa:6430; O14797; Q13243; Q16662; Q49AD6; Q6FGE0"	"mRNA processing"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway"	"6"	"0"	"561.8"	"606.2"	"537.3"	"487.5"	"519.0"	"553.5"	"667.4"	"752.4"	"1012.7"	"1652.2"	"2529.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5VT25"	"Serine/threonine-protein kinase MRCK alpha OS=Homo sapiens OX=9606 GN=CDC42BPA PE=1 SV=1"	"5"	"8"	"13"	"8"	"1732"	"197.2"	"6.58"	"2491.09"	"19.24"	"7"	"6"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00130, Pf00433, Pf00780, Pf08826, Pf15796"	"8476"	"ENSG00000143776"	"CDC42BPA"	"hsa:8476; O75039; Q59GZ1; Q5H9N9; Q5T797; Q5VT25; Q5VT26; Q5VT27; Q86XX2; Q86XX3; Q99646"	"Male infertility"	"CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RHOJ GTPase cycle"	"5"	"0"	"192.5"	"167.2"	"230.1"	"194.0"	"250.4"	"326.5"	"492.4"	"806.5"	"1110.9"	"1344.5"	"1673.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16775"	"Hydroxyacylglutathione hydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=HAGH PE=1 SV=2"	"17"	"3"	"9"	"3"	"308"	"33.8"	"8.12"	"1890.47"	"19.23"	"2"	"3"	"other metabolic processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00753, Pf16123"	"3029"	"ENSG00000063854"	"HAGH"	"A8K290; B4DP33; B4DRA7; E7EN93; hsa:3029; Q16775"	""	""	"0"	"0"	"140.2"	"119.3"	"140.8"	"142.9"	"160.1"	"155.2"	"155.2"	"194.7"	"243.3"	"360.0"	"542.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y697"	"Cysteine desulfurase, mitochondrial OS=Homo sapiens OX=9606 GN=NFS1 PE=1 SV=3"	"14"	"5"	"10"	"5"	"457"	"50.2"	"8.31"	"1896.58"	"19.20"	"5"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf00266"	"9054"	"ENSG00000244005"	"NFS1"	"B3KMA5; B4DXK9; E1P5R8; F5GYK5; hsa:9054; Q6P0L8; Q9NTZ5; Q9Y481; Q9Y697"	"Iron-sulfur cluster biogenesis"	""	"1"	"0"	"129.9"	"116.9"	"153.0"	"123.5"	"155.7"	"157.8"	"185.9"	"278.2"	"715.2"	"1330.0"	"1857.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NSD9"	"Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3"	"12"	"7"	"12"	"6"	"589"	"66.1"	"6.84"	"2069.75"	"19.16"	"6"	"6"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03483, Pf03484, Pf17759, Pf18262"	"10056"	"ENSG00000116120"	"FARSB"	"B4DFM0; hsa:10056; O95708; Q4ZFX1; Q57ZJ5; Q9NSD9; Q9NZZ6"	"VEGFA-VEGFR2 signaling; Amino acid metabolism"	"Cytosolic tRNA aminoacylation"	"3"	"1"	"392.8"	"410.9"	"378.9"	"292.5"	"414.0"	"394.6"	"479.8"	"608.3"	"942.2"	"2198.2"	"2799.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3A5"	"Ribosome maturation protein SBDS OS=Homo sapiens OX=9606 GN=SBDS PE=1 SV=4"	"31"	"7"	"13"	"7"	"250"	"28.7"	"8.75"	"2799.09"	"19.13"	"7"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;translation activity;nucleic acid binding activity"	"Pf01172, Pf09377, Pf20268"	"51119"	"ENSG00000126524"	"SBDS"	"A8K0P4; hsa:51119; Q96FX0; Q9NV53; Q9Y3A5"	"Genetic causes of porto-sinusoidal vascular disease"	""	"1"	"0"	"518.2"	"471.3"	"575.4"	"460.6"	"538.1"	"558.1"	"732.2"	"1213.1"	"3572.8"	"5533.9"	"5969.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62750"	"60S ribosomal protein L23a OS=Homo sapiens OX=9606 GN=RPL23A PE=1 SV=1"	"34"	"5"	"12"	"5"	"156"	"17.7"	"10.45"	"2301.15"	"19.11"	"5"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00276, Pf03939"	"6147"	"ENSG00000198242"	"RPL23A"	"B2R5B2; hsa:6147; P29316; P39024; P62750; Q92774"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"754.1"	"688.1"	"677.2"	"606.6"	"659.0"	"708.1"	"848.9"	"1040.0"	"1393.2"	"2091.5"	"3168.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60869"	"Endothelial differentiation-related factor 1 OS=Homo sapiens OX=9606 GN=EDF1 PE=1 SV=1"	"34"	"5"	"12"	"5"	"148"	"16.4"	"9.95"	"2591.25"	"19.07"	"5"	"3"	"other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01381, Pf08523"	"8721"	"ENSG00000107223"	"EDF1"	"hsa:8721; O60869; Q5T5T2; Q9UIM1"	""	""	"0"	"0"	"1528.7"	"1159.3"	"1267.7"	"1027.3"	"1111.7"	"1281.0"	"1566.3"	"1537.8"	"1625.3"	"1646.5"	"1488.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62304"	"Small nuclear ribonucleoprotein E OS=Homo sapiens OX=9606 GN=SNRPE PE=1 SV=1"	"55"	"4"	"10"	"4"	"92"	"10.8"	"9.44"	"1735.65"	"19.04"	"2"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01423"	"6635"	"ENSG00000182004"	"SNRPE"	"B2R5B9; hsa:6635; P08578; P62304; Q15498; Q5BKT2"	"mRNA processing"	"mRNA Splicing - Major Pathway; SARS-CoV-2 modulates host translation machinery; snRNP Assembly; RNA Polymerase II Transcription Termination; mRNA Splicing - Minor Pathway; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"8"	"0"	"152.2"	"119.8"	"131.5"	"107.4"	"121.2"	"138.1"	"154.6"	"184.1"	"263.6"	"427.4"	"799.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13442"	"28 kDa heat- and acid-stable phosphoprotein OS=Homo sapiens OX=9606 GN=PDAP1 PE=1 SV=1"	"38"	"6"	"10"	"6"	"181"	"20.6"	"8.87"	"2374.99"	"19.01"	"5"	"5"	"signal transduction"	"non-structural extracellular;plasma membrane;other membranes;cytosol;other cell component"	""	"Pf10252"	"11333"	"ENSG00000106244"	"PDAP1"	"D6W5S5; hsa:11333; Q13442; Q92906"	""	"Neutrophil degranulation"	"1"	"0"	"548.5"	"437.7"	"538.3"	"445.4"	"461.8"	"541.8"	"657.2"	"749.8"	"1973.1"	"2166.1"	"1844.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H3P2"	"Negative elongation factor A OS=Homo sapiens OX=9606 GN=NELFA PE=1 SV=3"	"10"	"4"	"13"	"4"	"528"	"57.2"	"9.03"	"2557.90"	"18.96"	"4"	"4"	"other biological processes"	"cytosol;nucleus"	"other molecular function"	""	"7469"	"ENSG00000185049"	"NELFA"	"A2A2T1; hsa:7469; O95392; Q9H3P2"	"Initiation of transcription and translation elongation at the HIV-1 LTR; 4p16.3 copy number variation"	"Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; TP53 Regulates Transcription of DNA Repair Genes"	"16"	"0"	"213.4"	"213.5"	"267.9"	"200.2"	"243.0"	"223.2"	"291.0"	"321.5"	"597.8"	"1039.7"	"1382.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15126"	"Phosphomevalonate kinase OS=Homo sapiens OX=9606 GN=PMVK PE=1 SV=3"	"42"	"7"	"13"	"7"	"192"	"22.0"	"5.73"	"2798.50"	"18.95"	"7"	"6"	"other metabolic processes;other biological processes"	"cytosol;other cytoplasmic organelle"	"kinase activity;other molecular function"	"Pf04275"	"10654"	"ENSG00000163344"	"PMVK"	"hsa:10654; Q15126; Q5TZW9"	"Cholesterol biosynthesis pathway; Mevalonate pathway; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Cholesterol synthesis disorders; Cholesterol metabolism; Enterocyte cholesterol metabolism"	"Activation of gene expression by SREBF (SREBP); Cholesterol biosynthesis"	"8"	"0"	"84.5"	"84.1"	"104.6"	"96.0"	"110.1"	"111.8"	"184.7"	"562.9"	"1757.3"	"3148.6"	"4758.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P83731"	"60S ribosomal protein L24 OS=Homo sapiens OX=9606 GN=RPL24 PE=1 SV=1"	"36"	"6"	"11"	"6"	"157"	"17.8"	"11.25"	"2388.44"	"18.95"	"5"	"4"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01246"	"6152"	"ENSG00000114391"	"RPL24"	"B2R4Y3; hsa:6152; P38663; P83731; Q6IBS3"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Peptide chain elongation; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"1152.2"	"1067.7"	"1158.2"	"951.0"	"1047.3"	"1111.5"	"1418.8"	"1555.8"	"2116.4"	"3392.9"	"5596.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P26373"	"60S ribosomal protein L13 OS=Homo sapiens OX=9606 GN=RPL13 PE=1 SV=4"	"26"	"7"	"12"	"7"	"211"	"24.2"	"11.65"	"2079.27"	"18.91"	"6"	"6"	"protein metabolism;other metabolic processes;developmental processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01294"	"6137"	"ENSG00000167526"	"RPL13"	"B4DLX3; F5H1S2; hsa:6137; P26373; Q3KQT8; Q567Q8; Q9BPX0"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"1053.0"	"836.8"	"1025.3"	"910.2"	"984.4"	"1073.5"	"1185.8"	"1350.4"	"1783.1"	"3190.4"	"5254.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86U42"	"Polyadenylate-binding protein 2 OS=Homo sapiens OX=9606 GN=PABPN1 PE=1 SV=3"	"22"	"6"	"10"	"6"	"306"	"32.7"	"5.06"	"1766.71"	"18.89"	"5"	"5"	"RNA metabolism OR transcription;other metabolic processes;transport;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"8106"	"ENSG00000100836"	"PABPN1"	"D3DS49; hsa:8106; O43484; Q86U42"	"mRNA processing"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs; Inhibition of Host mRNA Processing and RNA Silencing"	"6"	"0"	"919.1"	"861.1"	"1012.2"	"873.6"	"920.3"	"907.4"	"1129.8"	"1328.8"	"1560.6"	"2353.4"	"4019.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P36954"	"DNA-directed RNA polymerase II subunit RPB9 OS=Homo sapiens OX=9606 GN=POLR2I PE=1 SV=1"	"56"	"5"	"6"	"5"	"125"	"14.5"	"5.14"	"384.73"	"18.78"	"1"	"5"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01096, Pf02150"	"5438"	"ENSG00000105258"	"POLR2I"	"B2R5J2; hsa:5438; P36954; Q6NW05"	"Pyrimidine metabolism; Eukaryotic transcription initiation"	"mRNA Splicing - Major Pathway; Transcriptional regulation by small RNAs; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Inhibition of DNA recombination at telomere; PIWI-interacting RNA (piRNA) biogenesis; Processing of Capped Intron-Containing Pre-mRNA; Viral Messenger RNA Synthesis; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; MicroRNA (miRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Signaling by FGFR2 IIIa TM"	"43"	"0"	"322.1"	"326.5"	"314.4"	"291.6"	"346.5"	"242.3"	"397.4"	"476.3"	"636.8"	"974.5"	"1323.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q07020"	"60S ribosomal protein L18 OS=Homo sapiens OX=9606 GN=RPL18 PE=1 SV=2"	"19"	"4"	"10"	"4"	"188"	"21.6"	"11.72"	"1860.31"	"18.70"	"4"	"4"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf17135"	"6141"	"ENSG00000063177"	"RPL18"	"F8VWC5; hsa:6141; Q07020; Q8WTZ6"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"319.8"	"318.6"	"358.8"	"303.4"	"344.5"	"330.1"	"399.2"	"517.5"	"818.4"	"1421.9"	"2446.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43148"	"mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1"	"14"	"7"	"13"	"7"	"476"	"54.8"	"6.61"	"1901.05"	"18.66"	"6"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03291"	"8731"	"ENSG00000101654"	"RNMT"	"B0YJ90; D3DUJ5; hsa:8731; O43148; O94996; Q9UIJ9"	"mRNA processing; 15q25 copy number variation"	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE"	"5"	"0"	"512.2"	"476.6"	"560.5"	"471.0"	"532.2"	"555.7"	"627.1"	"771.3"	"1607.8"	"2708.9"	"3528.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63244"	"Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3"	"13"	"4"	"10"	"4"	"317"	"35.1"	"7.69"	"2088.01"	"18.63"	"4"	"4"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;cytosol;mitochondrion;translational apparatus;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;translation activity;other molecular function"	"Pf00400"	"10399"	"ENSG00000204628"	"RACK1"	"B3KTJ0; D3DWS0; hsa:10399; P25388; P63244; P99049; Q53HU2; Q5J8M6; Q5VLR4; Q6FH47"	"Androgen receptor signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; VEGFA-VEGFR2 signaling; Measles virus infection; Angiotensin II receptor type 1 pathway; TROP2 regulatory signaling; Interferon type I signaling pathways"	"Regulation of TNFR1 signaling; TNFR1-induced NF-kappa-B signaling pathway; TNFR1-mediated ceramide production"	"10"	"0"	"175.8"	"167.7"	"209.1"	"173.2"	"193.6"	"173.4"	"231.6"	"328.6"	"551.6"	"1305.2"	"3531.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IWI9"	"MAX gene-associated protein OS=Homo sapiens OX=9606 GN=MGA PE=1 SV=4"	"3"	"7"	"11"	"7"	"3065"	"336.0"	"6.90"	"1234.98"	"18.61"	"4"	"7"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00010, Pf00907, Pf16059"	"23269"	"ENSG00000174197"	"MGA"	"B9EGR5; E7ENI0; F5H7K2; hsa:23269; Q8IWI9; Q9H8R3; Q9H9N7; Q9UG69; Q9Y4E9"	"Pathways affected in adenoid cystic carcinoma"	"Transcriptional Regulation by E2F6"	"2"	"0"	"587.2"	"508.8"	"659.6"	"585.6"	"603.3"	"688.5"	"678.9"	"788.1"	"1202.6"	"1821.6"	"2362.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P12236"	"ADP/ATP translocase 3 OS=Homo sapiens OX=9606 GN=SLC25A6 PE=1 SV=4"	"21"	"6"	"12"	"1"	"298"	"32.8"	"9.74"	"2126.84"	"18.54"	"6"	"6"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity"	"Pf00153"	"293"	"ENSG00000169100"	"SLC25A6"	"hsa:293; P12236; Q96C49"	"Electron transport chain: OXPHOS system in mitochondria; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Mitochondrial protein import; Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane; Influenza Virus Induced Apoptosis; Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization"	"7"	"0"	"35.9"	"30.7"	"35.9"	"35.0"	"40.1"	"35.0"	"43.3"	"55.4"	"151.4"	"291.2"	"419.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06730"	"Eukaryotic translation initiation factor 4E OS=Homo sapiens OX=9606 GN=EIF4E PE=1 SV=2"	"24"	"5"	"9"	"5"	"217"	"25.1"	"6.15"	"1500.42"	"18.49"	"4"	"5"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01652"	"1977"	"ENSG00000151247"	"EIF4E"	"B7Z6V1; D6RCQ6; hsa:1977; P06730; Q96E95"	"Translation factors; Leptin signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Interleukin-1 (IL-1) structural pathway; Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4); Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; 4-hydroxytamoxifen, dexamethasone, and retinoic acids regulation of p27 expression; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Prader-Willi and Angelman syndrome; PI3K-Akt signaling pathway; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Head and neck squamous cell carcinoma; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; Host-pathogen interaction of human coronaviruses - MAPK signaling; Hypertrophy model; Interferon type I signaling pathways"	"Deadenylation of mRNA; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; mTORC1-mediated signalling"	"31"	"0"	"111.7"	"105.7"	"134.2"	"116.4"	"134.1"	"160.7"	"169.8"	"253.9"	"1152.8"	"2620.8"	"3695.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UII2"	"ATPase inhibitor, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5IF1 PE=1 SV=1"	"25"	"5"	"12"	"5"	"106"	"12.2"	"9.35"	"1918.76"	"18.48"	"5"	"5"	"cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"mitochondrion;other cell component"	"enzyme regulator activity;other molecular function"	"Pf04568"	"93974"	"ENSG00000130770; ENSG00000285390"	"ATP5IF1"	"hsa:93974; Q5JXL8; Q6IAQ7; Q9BSL9; Q9UII2"	"Electron transport chain: OXPHOS system in mitochondria"	""	"1"	"0"	"960.1"	"763.6"	"868.6"	"818.4"	"856.8"	"899.6"	"1027.7"	"1060.3"	"2075.0"	"3275.0"	"4294.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6I9Y2"	"THO complex subunit 7 homolog OS=Homo sapiens OX=9606 GN=THOC7 PE=1 SV=3"	"28"	"5"	"9"	"5"	"204"	"23.7"	"5.67"	"1713.32"	"18.44"	"4"	"5"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf05615"	"80145"	"ENSG00000163634"	"THOC7"	"hsa:80145; Q6I9Y2; Q6P1L3; Q8WUF2; Q9H5H0"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"3"	"0"	"475.8"	"416.9"	"503.4"	"415.1"	"478.1"	"522.5"	"619.2"	"711.7"	"1154.0"	"1815.9"	"2873.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49757"	"Protein numb homolog OS=Homo sapiens OX=9606 GN=NUMB PE=1 SV=2"	"10"	"5"	"10"	"5"	"651"	"70.8"	"8.51"	"1472.80"	"18.42"	"3"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00640, Pf06311"	"8650"	"ENSG00000133961"	"NUMB"	"B1P2N5; B1P2N6; B1P2N7; B1P2N8; B1P2N9; B4E2B1; hsa:8650; P49757; Q6NUQ7; Q86SY1; Q8WW73; Q9UBG1; Q9UEQ4; Q9UKE8; Q9UKE9; Q9UKF0; Q9UQJ4"	"Notch signaling; VEGFA-VEGFR2 signaling; Head and neck squamous cell carcinoma; Neurogenesis regulation in the olfactory epithelium; TROP2 regulatory signaling; Notch signaling pathway"	"Recycling pathway of L1; Degradation of GLI1 by the proteasome; Hedgehog 'on' state; Activated NOTCH1 Transmits Signal to the Nucleus"	"10"	"0"	"111.7"	"107.6"	"106.7"	"101.3"	"119.1"	"126.1"	"215.0"	"482.8"	"817.7"	"1146.3"	"1033.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQG0"	"Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2"	"5"	"4"	"7"	"4"	"1328"	"148.8"	"9.28"	"1214.24"	"18.39"	"3"	"3"	"cell organization and biogenesis;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04931"	"10514"	"ENSG00000132382"	"MYBBP1A"	"hsa:10514; Q86VM3; Q9BQG0; Q9BW49; Q9P0V5; Q9UF99"	"Energy metabolism; 10q11.21q11.23 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression"	"3"	"0"	"57.8"	"53.9"	"74.1"	"67.0"	"65.2"	"65.0"	"87.3"	"97.5"	"169.1"	"290.7"	"389.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08559"	"Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial OS=Homo sapiens OX=9606 GN=PDHA1 PE=1 SV=3"	"14"	"5"	"13"	"5"	"390"	"43.3"	"8.06"	"2694.91"	"18.37"	"5"	"5"	"other metabolic processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00676"	"5160"	"ENSG00000131828"	"PDHA1"	"A5YVE9; B2R5P7; B7Z3T7; B7Z3X5; hsa:5160; P08559; Q53H41; Q5JPT8; Q9NP12; Q9UBJ8; Q9UBU0; Q9UNG4; Q9UNG5"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Lipid metabolism pathway; PI3K/AKT/mTOR - vitamin D3 signaling; Metabolic reprogramming in colon cancer; Thiamine metabolic pathways; TCA cycle in senescence; Neuroinflammation and glutamatergic signaling; Acetylcholine synthesis; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"Glyoxylate metabolism and glycine degradation; Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid"	"15"	"0"	"704.7"	"654.2"	"689.1"	"655.1"	"663.1"	"724.7"	"815.4"	"1067.0"	"1314.8"	"2144.5"	"3132.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y265"	"RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1 PE=1 SV=1"	"10"	"4"	"8"	"4"	"456"	"50.2"	"6.42"	"996.81"	"18.37"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf06068, Pf17856"	"8607"	"ENSG00000175792; ENSG00000284901"	"RUVBL1"	"B2R5S0; hsa:8607; P82276; Q1KMR0; Q53HK5; Q53HL7; Q53Y27; Q9BSX9; Q9Y265"	"Gastric cancer network 1; lncRNA in canonical Wnt signaling and colorectal cancer"	"UCH proteinases; Ub-specific processing proteases; Deposition of new CENPA-containing nucleosomes at the centromere; Formation of the beta-catenin:TCF transactivating complex; Telomere Extension By Telomerase; HATs acetylate histones; DNA Damage Recognition in GG-NER"	"9"	"0"	"257.2"	"264.0"	"283.4"	"280.2"	"286.5"	"271.0"	"335.7"	"454.0"	"803.4"	"1714.5"	"2651.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQP7"	"Mitochondrial genome maintenance exonuclease 1 OS=Homo sapiens OX=9606 GN=MGME1 PE=1 SV=1"	"19"	"5"	"9"	"5"	"344"	"39.4"	"7.68"	"1409.20"	"18.30"	"4"	"5"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response"	"mitochondrion"	"other molecular function"	"Pf12705"	"92667"	"ENSG00000125871"	"MGME1"	"B2RDG5; D3DW29; hsa:92667; Q96SW3; Q9BQP7"	"Primary ovarian insufficiency"	""	"1"	"0"	"67.3"	"61.6"	"73.1"	"77.1"	"83.3"	"83.1"	"97.0"	"141.4"	"554.3"	"1219.1"	"1683.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15226"	"NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2"	"10"	"6"	"11"	"6"	"690"	"77.6"	"8.79"	"2849.02"	"18.29"	"6"	"5"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01424, Pf01585"	"55922"	"ENSG00000186416"	"NKRF"	"G3V1N1; hsa:55922; O15226; Q4VC41; Q9UJ91"	"Pathogenesis of SARS-CoV-2 mediated by nsp9-nsp10 complex; Network map of SARS-CoV-2 signaling pathway"	""	"2"	"0"	"552.4"	"492.2"	"514.9"	"478.4"	"583.5"	"584.8"	"627.2"	"695.6"	"919.0"	"1426.0"	"2062.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q05397"	"Focal adhesion kinase 1 OS=Homo sapiens OX=9606 GN=PTK2 PE=1 SV=2"	"6"	"6"	"11"	"6"	"1052"	"119.2"	"6.62"	"2348.37"	"18.27"	"6"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;kinase activity;other molecular function"	"Pf00373, Pf03623, Pf07714, Pf18038"	"5747"	"ENSG00000169398"	"PTK2"	"B4E2N6; F5H4S4; hsa:5747; J3QT16; Q05397; Q14291; Q8IYN9; Q9UD85"	"Androgen receptor signaling pathway; Integrin-mediated cell adhesion; RANKL/RANK signaling pathway; Leptin signaling pathway; Prolactin signaling pathway; Corticotropin-releasing hormone signaling pathway; Alpha 6 beta 4 signaling pathway; Primary focal segmental glomerulosclerosis (FSGS); Apoptosis-related network due to altered Notch3 in ovarian cancer; Focal adhesion; Hepatocyte growth factor receptor signaling; Overview of nanoparticle effects; MFAP5-mediated ovarian cancer cell motility and invasiveness; RAC1/PAK1/p38/MMP2 pathway; Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Prion disease pathway; PI3K-Akt signaling pathway; EGF/EGFR signaling pathway; Hippo-Merlin signaling dysregulation; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Small cell lung cancer; Gastrin signaling pathway; Netrin-UNC5B signaling pathway; Pleural mesothelioma; Regulation of actin cytoskeleton; 2q13 copy number variation syndrome; TROP2 regulatory signaling; A network map of Macrophage-stimulating protein (MSP) signaling; ErbB signaling pathway"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; EPHB-mediated forward signaling; Signal regulatory protein family interactions; DCC mediated attractive signaling; RAF/MAP kinase cascade; VEGFA-VEGFR2 Pathway; Estrogen-dependent nuclear events downstream of ESR-membrane signaling; NCAM signaling for neurite out-growth; MET activates PTK2 signaling; GRB2:SOS provides linkage to MAPK signaling for Integrins ; p130Cas linkage to MAPK signaling for integrins; Apoptotic cleavage of cellular proteins"	"48"	"0"	"260.9"	"246.0"	"288.5"	"253.7"	"339.5"	"362.5"	"662.4"	"1430.4"	"2459.5"	"2994.6"	"2795.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P24941"	"Cyclin-dependent kinase 2 OS=Homo sapiens OX=9606 GN=CDK2 PE=1 SV=2"	"16"	"4"	"9"	"3"	"298"	"33.9"	"8.68"	"1577.18"	"18.25"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"1017"	"ENSG00000123374"	"CDK2"	"A8K7C6; hsa:1017; O75100; P24941"	"miRNA regulation of DNA damage response; Cell cycle; Thyroid stimulating hormone (TSH) signaling pathway; Glioblastoma signaling pathways; Oncostatin M signaling pathway; Spinal cord injury; Retinoblastoma gene in cancer; Aryl hydrocarbon receptor pathway; Vitamin D receptor pathway; PI3K-Akt signaling pathway; G1 to S cell cycle control; Measles virus infection; Small cell lung cancer; DNA replication; p53 transcriptional gene network; Pleural mesothelioma; Sphingolipid metabolism in senescence; Urotensin-II-mediated signaling pathway; ID signaling pathway; TROP2 regulatory signaling; DNA damage response"	"Senescence-Associated Secretory Phenotype (SASP); Meiotic recombination; DNA Damage/Telomere Stress Induced Senescence; Transcriptional regulation of granulopoiesis; TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; Regulation of TP53 Degradation; SCF(Skp2)-mediated degradation of p27/p21; Regulation of TP53 Activity through Phosphorylation; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; G2 Phase; Cyclin D associated events in G1; Defective binding of RB1 mutants to E2F1,(E2F2, E2F3); Telomere Extension By Telomerase; Regulation of APC/C activators between G1/S and early anaphase; Factors involved in megakaryocyte development and platelet production; Processing of DNA double-strand break ends; Cyclin A/B1/B2 associated events during G2/M transition; G0 and Early G1; Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes; p53-Dependent G1 DNA Damage Response; PTK6 Regulates Cell Cycle"	"47"	"0"	"144.9"	"157.2"	"142.4"	"103.8"	"142.7"	"131.9"	"198.6"	"318.5"	"667.0"	"1484.4"	"1989.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14168"	"MAGUK p55 subfamily member 2 OS=Homo sapiens OX=9606 GN=MPP2 PE=1 SV=3"	"11"	"4"	"8"	"3"	"576"	"64.5"	"6.77"	"1784.98"	"18.22"	"4"	"4"	"cell-cell signaling;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	""	"Pf00595, Pf00625, Pf02828, Pf07653"	"4355"	"ENSG00000108852"	"MPP2"	"B4DGE9; B4DRJ0; B7Z3G8; E7EV80; E7EV91; E7EX01; hsa:4355; Q14168; Q53ES9; Q5CZB9; Q9BQJ2"	""	""	"0"	"0"	"47.1"	"61.0"	"40.3"	"40.9"	"43.5"	"45.6"	"61.2"	"90.5"	"433.4"	"1347.3"	"1912.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60660"	"Myosin light polypeptide 6 OS=Homo sapiens OX=9606 GN=MYL6 PE=1 SV=2"	"34"	"5"	"10"	"5"	"151"	"16.9"	"4.65"	"1826.52"	"18.19"	"4"	"4"	"other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	""	"4637"	"ENSG00000092841"	"MYL6"	"hsa:4637; P16475; P24572; P24573; P60660; Q12790; Q561V9; Q6IAZ0; Q6IPY5"	"Ciliary landscape"	"RHO GTPases activate CIT; EPHA-mediated growth cone collapse; Sema4D induced cell migration and growth-cone collapse; Smooth Muscle Contraction; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; RHO GTPases activate PAKs"	"8"	"0"	"293.9"	"298.7"	"338.2"	"290.0"	"307.3"	"273.2"	"365.3"	"455.0"	"1155.7"	"2899.5"	"4706.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UIG0"	"Tyrosine-protein kinase BAZ1B OS=Homo sapiens OX=9606 GN=BAZ1B PE=1 SV=2"	"4"	"5"	"11"	"5"	"1483"	"170.8"	"8.48"	"2332.96"	"18.15"	"5"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00439, Pf00628, Pf10537, Pf15612, Pf15613"	"9031"	"ENSG00000009954"	"BAZ1B"	"B9EGK3; D3DXE9; hsa:9031; O95039; O95247; O95277; Q6P1K4; Q86UJ6; Q9UIG0"	"IL-18 signaling pathway; 7q11.23 copy number variation syndrome; 10q11.21q11.23 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"	"5"	"0"	"386.4"	"336.3"	"380.7"	"368.4"	"440.7"	"431.2"	"475.4"	"545.2"	"1455.1"	"2045.2"	"2313.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15084"	"Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1"	"16"	"5"	"8"	"5"	"440"	"48.1"	"5.08"	"1314.14"	"18.15"	"3"	"5"	"protein metabolism;other metabolic processes;stress response"	"non-structural extracellular;plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00085"	"10130"	"ENSG00000143870"	"PDIA6"	"B3KY95; B5MCQ5; B7Z254; B7Z4M8; F8WA83; hsa:10130; Q15084; Q53RC7; Q6ZSH5; Q99778"	"Photodynamic therapy-induced unfolded protein response; VEGFA-VEGFR2 signaling"	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; XBP1(S) activates chaperone genes"	"5"	"0"	"439.4"	"308.6"	"490.4"	"405.4"	"468.6"	"500.6"	"540.2"	"562.4"	"763.4"	"934.5"	"1090.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H9A6"	"Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1"	"12"	"6"	"11"	"6"	"602"	"68.2"	"6.43"	"1708.66"	"18.12"	"5"	"6"	""	""	""	"Pf00560, Pf13855"	"55631"	"ENSG00000066557"	"LRRC40"	"hsa:55631; Q9BTR7; Q9H9A6; Q9NSK1; Q9NXC1"	""	""	"0"	"0"	"123.6"	"129.1"	"140.0"	"122.5"	"134.3"	"128.0"	"152.0"	"162.9"	"428.2"	"2181.9"	"3388.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UEW8"	"STE20/SPS1-related proline-alanine-rich protein kinase OS=Homo sapiens OX=9606 GN=STK39 PE=1 SV=3"	"7"	"2"	"10"	"1"	"545"	"59.4"	"6.29"	"2011.56"	"18.12"	"2"	"2"	"protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf12202"	"27347"	"ENSG00000198648"	"STK39"	"hsa:27347; O14774; Q53S90; Q53SL7; Q53SS1; Q9UER4; Q9UEW8; X5D9C8"	""	""	"0"	"0"	"14.2"	"12.8"	"14.7"	"18.3"	"11.3"	"13.1"	"18.3"	"31.9"	"68.8"	"118.2"	"156.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96E11"	"Ribosome-recycling factor, mitochondrial OS=Homo sapiens OX=9606 GN=MRRF PE=1 SV=1"	"25"	"4"	"6"	"4"	"262"	"29.3"	"9.79"	"717.97"	"18.07"	"2"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"mitochondrion"	"translation activity"	"Pf01765"	"92399"	"ENSG00000148187"	"MRRF"	"A8K6D8; A8K6Z4; B7Z4X5; B7Z6P7; hsa:92399; Q5RKT1; Q5T7T0; Q5T7T1; Q5T7T2; Q5T7T3; Q5T7T4; Q5T7T5; Q96E11"	""	"Mitochondrial translation termination"	"1"	"0"	"196.9"	"149.4"	"189.8"	"185.3"	"214.7"	"217.0"	"239.6"	"273.7"	"531.9"	"764.6"	"838.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P39687"	"Acidic leucine-rich nuclear phosphoprotein 32 family member A OS=Homo sapiens OX=9606 GN=ANP32A PE=1 SV=1"	"23"	"6"	"11"	"5"	"249"	"28.6"	"4.09"	"2428.94"	"18.07"	"5"	"5"	"transport;signal transduction;other biological processes"	"ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf14580"	"8125"	"ENSG00000140350"	"ANP32A"	"B2R6T4; hsa:8125; P39687; Q53FK4; Q5J8L8; Q7M4N6"	"IL-18 signaling pathway"	"HuR (ELAVL1) binds and stabilizes mRNA"	"2"	"1"	"637.8"	"645.0"	"688.6"	"567.9"	"701.1"	"760.4"	"911.8"	"1058.3"	"1388.1"	"1754.2"	"2301.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96JM3"	"Chromosome alignment-maintaining phosphoprotein 1 OS=Homo sapiens OX=9606 GN=CHAMP1 PE=1 SV=2"	"10"	"7"	"11"	"7"	"812"	"89.0"	"8.44"	"2756.81"	"18.04"	"6"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	""	"283489"	"ENSG00000198824"	"CHAMP1"	"B3KU06; hsa:283489; Q6P181; Q8NC88; Q96JM3; Q9BST0"	""	""	"0"	"0"	"863.6"	"640.3"	"797.1"	"728.1"	"746.3"	"757.6"	"848.8"	"928.0"	"1486.5"	"2440.4"	"2740.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P36578"	"60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5"	"15"	"6"	"13"	"6"	"427"	"47.7"	"11.06"	"2755.64"	"18.04"	"6"	"5"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00573, Pf14374"	"6124"	"ENSG00000174444"	"RPL4"	"A8K502; hsa:6124; P36578; P39029; Q4VBR0; Q969Z9"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"519.4"	"602.9"	"537.3"	"439.7"	"506.0"	"552.4"	"713.7"	"887.5"	"1449.0"	"2902.8"	"4600.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60701"	"UDP-glucose 6-dehydrogenase OS=Homo sapiens OX=9606 GN=UGDH PE=1 SV=1"	"15"	"6"	"9"	"6"	"494"	"55.0"	"7.12"	"1422.96"	"17.96"	"4"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes"	"cytosol;nucleus"	"other molecular function"	"Pf00984, Pf03720, Pf03721"	"7358"	"ENSG00000109814"	"UGDH"	"B3KUU2; B4DN25; hsa:7358; O60589; O60701"	"UDP-derived sugars synthesis in fibroblasts; Glucuronidation"	"Formation of the active cofactor, UDP-glucuronate"	"3"	"0"	"175.7"	"185.2"	"181.3"	"144.8"	"189.3"	"210.3"	"233.6"	"305.4"	"807.4"	"1698.8"	"2044.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62829"	"60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1"	"41"	"4"	"7"	"4"	"140"	"14.9"	"10.51"	"1295.94"	"17.95"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00238"	"9349"	"ENSG00000125691"	"RPL23"	"hsa:9349; P23131; P24048; P62829; Q29246; Q3SWV7; Q6P5S1"	"Cytoplasmic ribosomal proteins; 17q12 copy number variation syndrome"	"Regulation of expression of SLITs and ROBOs; Response of EIF2AK4 (GCN2) to amino acid deficiency; SRP-dependent cotranslational protein targeting to membrane; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"15"	"0"	"270.5"	"213.4"	"290.3"	"270.5"	"284.5"	"272.9"	"339.1"	"387.0"	"722.0"	"1150.5"	"1811.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P27694"	"Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2"	"6"	"4"	"10"	"4"	"616"	"68.1"	"7.21"	"1959.71"	"17.94"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01336, Pf04057, Pf08646, Pf16900"	"6117"	"ENSG00000132383"	"RPA1"	"A8K0Y9; hsa:6117; P27694; Q59ES9"	"Homologous recombination; Retinoblastoma gene in cancer; ATR signaling; G1 to S cell cycle control; DNA replication; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"SUMOylation of DNA damage response and repair proteins; PCNA-Dependent Long Patch Base Excision Repair; Fanconi Anemia Pathway; Regulation of HSF1-mediated heat shock response; Regulation of TP53 Activity through Phosphorylation; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Meiotic recombination; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; HSF1 activation; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; Dual Incision in GG-NER; Removal of the Flap Intermediate; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"39"	"0"	"131.5"	"145.4"	"167.7"	"131.7"	"158.5"	"136.9"	"176.7"	"230.8"	"378.3"	"614.5"	"1093.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WVC0"	"RNA polymerase-associated protein LEO1 OS=Homo sapiens OX=9606 GN=LEO1 PE=1 SV=1"	"15"	"8"	"14"	"8"	"666"	"75.4"	"4.51"	"2734.78"	"17.93"	"8"	"6"	"cell-cell signaling;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytoskeleton;nucleus"	"other molecular function"	"Pf04004"	"123169"	"ENSG00000166477"	"LEO1"	"hsa:123169; Q8WVC0; Q96N99"	"Endoderm differentiation"	"E3 ubiquitin ligases ubiquitinate target proteins; Formation of the beta-catenin:TCF transactivating complex; Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events"	"6"	"0"	"781.6"	"740.8"	"832.5"	"748.3"	"762.3"	"809.0"	"922.0"	"1151.0"	"1490.5"	"1816.5"	"2425.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P53041"	"Serine/threonine-protein phosphatase 5 OS=Homo sapiens OX=9606 GN=PPP5C PE=1 SV=1"	"11"	"5"	"8"	"5"	"499"	"56.8"	"6.28"	"1265.81"	"17.90"	"3"	"5"	"cell cycle OR cell proliferation;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00149, Pf00515, Pf08321"	"5536"	"ENSG00000011485"	"PPP5C"	"hsa:5536; P53041; Q16722; Q53XV2"	"MAPK signaling pathway; ATM signaling in development and disease"	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Negative regulation of MAPK pathway; ESR-mediated signaling"	"5"	"0"	"118.2"	"122.1"	"129.0"	"115.8"	"126.6"	"112.0"	"156.3"	"247.2"	"1519.2"	"3630.1"	"5614.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5VYK3"	"Proteasome adapter and scaffold protein ECM29 OS=Homo sapiens OX=9606 GN=ECPAS PE=1 SV=2"	"3"	"5"	"9"	"5"	"1845"	"204.2"	"7.12"	"1398.60"	"17.81"	"4"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response"	"cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf13001"	""	"ENSG00000136813"	"ECPAS"	"O15074; Q5VYK3; Q8WU82"	""	""	"0"	"0"	"76.9"	"70.5"	"121.6"	"77.2"	"103.1"	"96.2"	"104.8"	"146.4"	"464.4"	"910.5"	"1220.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WVV9"	"Heterogeneous nuclear ribonucleoprotein L-like OS=Homo sapiens OX=9606 GN=HNRNPLL PE=1 SV=1"	"8"	"4"	"11"	"3"	"542"	"60.0"	"7.72"	"1548.30"	"17.76"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf11835, Pf13893"	"92906"	"ENSG00000143889"	"HNRNPLL"	"hsa:92906; Q53T80; Q5JB51; Q5JB52; Q659B9; Q8IVH5; Q8IVH6; Q8WVV9; Q96HR5"	""	""	"0"	"0"	"54.9"	"64.6"	"95.1"	"76.6"	"89.2"	"66.4"	"104.9"	"137.9"	"266.7"	"518.5"	"826.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43809"	"Cleavage and polyadenylation specificity factor subunit 5 OS=Homo sapiens OX=9606 GN=NUDT21 PE=1 SV=1"	"23"	"7"	"12"	"7"	"227"	"26.2"	"8.82"	"2210.65"	"17.74"	"5"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13869"	"11051"	"ENSG00000167005"	"NUDT21"	"hsa:11051; O43809; Q6IB85; Q6NE84"	"mRNA processing"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"5"	"0"	"1074.9"	"1063.0"	"1017.2"	"962.3"	"1030.6"	"982.9"	"1234.1"	"1526.1"	"1977.2"	"3782.1"	"7046.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y6E2"	"Basic leucine zipper and W2 domain-containing protein 2 OS=Homo sapiens OX=9606 GN=BZW2 PE=1 SV=1"	"8"	"2"	"3"	"2"	"419"	"48.1"	"6.68"	""	"17.74"	""	"2"	"other biological processes"	"other cell component"	""	"Pf02020"	"28969"	"ENSG00000136261"	"BZW2"	"A4D123; hsa:28969; Q3B779; Q96JW5; Q9H3F7; Q9Y6E2"	""	""	"0"	"0"	"42.1"	"37.2"	"49.9"	"48.4"	"41.1"	"46.6"	"43.3"	"63.5"	"218.3"	"1123.9"	"1964.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96C36"	"Pyrroline-5-carboxylate reductase 2 OS=Homo sapiens OX=9606 GN=PYCR2 PE=1 SV=1"	"10"	"3"	"6"	"2"	"320"	"33.6"	"7.77"	"1402.87"	"17.73"	"3"	"3"	"other metabolic processes;stress response"	"mitochondrion"	"other molecular function"	"Pf03807, Pf14748"	"29920"	"ENSG00000143811"	"PYCR2"	"A8K798; hsa:29920; Q7Z515; Q96C36; Q9Y5J4"	"Metabolic reprogramming in colon cancer"	"Glutamate and glutamine metabolism"	"2"	"1"	"74.4"	"64.3"	"76.6"	"66.6"	"83.9"	"80.7"	"95.5"	"114.3"	"175.3"	"388.3"	"599.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09622"	"Dihydrolipoyl dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=DLD PE=1 SV=2"	"9"	"5"	"9"	"5"	"509"	"54.1"	"7.85"	"1573.18"	"17.68"	"4"	"5"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytoskeleton;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf02852, Pf07992"	"1738"	"ENSG00000091140"	"DLD"	"B2R5X0; B4DHG0; B4DT69; hsa:1738; P09622; Q14131; Q14167; Q59EV8; Q8WTS4"	"Fatty acid beta-oxidation; TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Tryptophan metabolism; 7q11.23 copy number variation syndrome; Neuroinflammation and glutamatergic signaling; Glycolysis and gluconeogenesis; 10q11.21q11.23 copy number variation syndrome; Metabolic Epileptic Disorders; TCA cycle (aka Krebs or citric acid cycle)"	"Lysine catabolism; Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid; Citric acid cycle (TCA cycle); Branched-chain amino acid catabolism; Glycine degradation"	"18"	"0"	"283.5"	"228.7"	"267.5"	"255.7"	"272.4"	"306.0"	"341.4"	"420.2"	"931.4"	"2675.7"	"3988.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49755"	"Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2"	"17"	"3"	"8"	"3"	"219"	"25.0"	"7.44"	"1784.58"	"17.63"	"3"	"3"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"transporter activity;other molecular function"	"Pf01105"	"10972"	"ENSG00000170348"	"TMED10"	"B2R605; hsa:10972; P49755; Q15602; Q16536; Q86TC2; Q86TS5"	"mRNA processing; 5q35 copy number variation"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport; COPII-mediated vesicle transport; Cargo concentration in the ER"	"6"	"0"	"78.8"	"96.2"	"103.0"	"88.4"	"90.9"	"90.8"	"115.7"	"172.6"	"490.5"	"1302.8"	"2044.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q02878"	"60S ribosomal protein L6 OS=Homo sapiens OX=9606 GN=RPL6 PE=1 SV=3"	"19"	"6"	"12"	"6"	"288"	"32.7"	"10.58"	"2086.17"	"17.61"	"6"	"6"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01159, Pf03868"	"6128"	"ENSG00000089009"	"RPL6"	"hsa:6128; Q02878; Q2M3Q3; Q8WW97"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"550.8"	"615.6"	"545.9"	"477.4"	"554.7"	"592.0"	"703.8"	"911.8"	"1327.7"	"2364.6"	"3693.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60508"	"Pre-mRNA-processing factor 17 OS=Homo sapiens OX=9606 GN=CDC40 PE=1 SV=1"	"10"	"6"	"11"	"6"	"579"	"65.5"	"7.06"	"1759.49"	"17.59"	"5"	"6"	"RNA metabolism OR transcription;other metabolic processes;developmental processes"	"nucleus"	"nucleic acid binding activity"	"Pf00400"	"51362"	"ENSG00000168438"	"CDC40"	"B2RBC5; hsa:51362; O60508; O75471; Q5SRN0; Q9UPG1"	"mRNA processing"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway"	"5"	"0"	"394.5"	"345.9"	"408.8"	"370.9"	"392.4"	"402.4"	"456.4"	"524.4"	"747.1"	"1699.6"	"3431.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30533"	"Alpha-2-macroglobulin receptor-associated protein OS=Homo sapiens OX=9606 GN=LRPAP1 PE=1 SV=1"	"18"	"7"	"13"	"7"	"357"	"41.4"	"8.78"	"2485.50"	"17.56"	"7"	"6"	"transport;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf06400, Pf06401"	"4043"	"ENSG00000163956"	"LRPAP1"	"D3DVR9; hsa:4043; P30533; Q2M310; Q53HQ3; Q53HS6"	"Cholesterol metabolism"	""	"1"	"0"	"426.5"	"390.8"	"417.5"	"375.4"	"451.2"	"479.5"	"650.6"	"1325.0"	"4170.7"	"5650.1"	"4691.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UMR2"	"ATP-dependent RNA helicase DDX19B OS=Homo sapiens OX=9606 GN=DDX19B PE=1 SV=1"	"6"	"4"	"10"	"1"	"479"	"53.9"	"6.30"	"1939.62"	"17.49"	"4"	"4"	"other metabolic processes;transport"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"11269"	"ENSG00000157349"	"DDX19B"	"B3KNE9; B4DXS6; E7EMK4; hsa:11269; Q6FIB7; Q6IAE0; Q96KE7; Q9H0U0; Q9UMR2"	""	""	"0"	"0"	"53.0"	"20.9"	"57.4"	"65.5"	"36.2"	"53.0"	"66.5"	"74.3"	"123.6"	"172.2"	"212.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55735"	"Protein SEC13 homolog OS=Homo sapiens OX=9606 GN=SEC13 PE=1 SV=3"	"16"	"4"	"8"	"4"	"322"	"35.5"	"5.48"	"1721.43"	"17.48"	"4"	"4"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00400"	"6396"	"ENSG00000157020"	"SEC13"	"A8MV37; B4DXJ1; hsa:6396; P55735; Q5BJF0; Q9BRM6; Q9BUG7"	"Sterol regulatory element-binding proteins (SREBP) signaling"	"ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; snRNP Assembly; Separation of Sister Chromatids; HCMV Late Events; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; HCMV Early Events; EML4 and NUDC in mitotic spindle formation; Amino acids regulate mTORC1; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; COPII-mediated vesicle transport; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Postmitotic nuclear pore complex (NPC) reformation"	"40"	"0"	"280.2"	"281.1"	"348.3"	"283.1"	"353.5"	"357.5"	"424.1"	"644.6"	"1311.8"	"1681.8"	"2287.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBU8"	"Mortality factor 4-like protein 1 OS=Homo sapiens OX=9606 GN=MORF4L1 PE=1 SV=2"	"9"	"3"	"7"	"3"	"362"	"41.4"	"9.28"	"1442.71"	"17.47"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf05712, Pf11717"	"10933"	"ENSG00000185787"	"MORF4L1"	"B4DKN6; B7Z6R1; D3DW88; hsa:10933; O95899; Q5QTS1; Q6NVX8; Q86YT7; Q9HBP6; Q9NSW5; Q9UBU8"	"Pathways affected in adenoid cystic carcinoma"	"HATs acetylate histones"	"2"	"0"	"106.0"	"115.9"	"130.9"	"100.0"	"122.4"	"139.2"	"145.4"	"190.6"	"306.7"	"458.7"	"552.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HAU0"	"Pleckstrin homology domain-containing family A member 5 OS=Homo sapiens OX=9606 GN=PLEKHA5 PE=1 SV=1"	"6"	"5"	"10"	"5"	"1116"	"127.4"	"7.53"	"1964.75"	"17.40"	"5"	"5"	"developmental processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00169, Pf00397"	"54477"	"ENSG00000052126"	"PLEKHA5"	"A0JP03; B4DGS1; E9PHQ3; F5H0I0; hsa:54477; Q6NSF8; Q86ST7; Q8N3K6; Q96DY9; Q9BVR4; Q9C0H7; Q9H924; Q9HAU0; Q9NVK8"	""	"Synthesis of PIPs at the plasma membrane"	"1"	"0"	"468.5"	"360.1"	"522.3"	"483.4"	"502.8"	"542.0"	"577.0"	"655.3"	"973.8"	"1368.7"	"1661.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46776"	"60S ribosomal protein L27a OS=Homo sapiens OX=9606 GN=RPL27A PE=1 SV=2"	"27"	"4"	"11"	"4"	"148"	"16.6"	"11.00"	"2206.65"	"17.36"	"4"	"3"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;other cell component"	"other molecular function"	"Pf00828"	"6157"	"ENSG00000166441"	"RPL27A"	"B2R4B3; hsa:6157; P46776"	"Cytoplasmic ribosomal proteins"	"Major pathway of rRNA processing in the nucleolus and cytosol; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"485.9"	"385.7"	"545.0"	"469.3"	"545.2"	"501.5"	"600.9"	"787.5"	"1223.0"	"2080.9"	"3333.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NZJ9"	"Diphosphoinositol polyphosphate phosphohydrolase 2 OS=Homo sapiens OX=9606 GN=NUDT4 PE=1 SV=2"	"26"	"6"	"10"	"2"	"180"	"20.3"	"6.35"	"1450.69"	"17.33"	"4"	"6"	"other metabolic processes;signal transduction"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00293"	"11163"	"ENSG00000173598"	"NUDT4"	"B7Z916; hsa:11163; Q4AEJ6; Q53EZ2; Q68DD7; Q9NPC5; Q9NS30; Q9NZJ9; Q9NZK0; Q9NZK1"	""	"Synthesis of pyrophosphates in the cytosol"	"1"	"4"	"80.7"	"86.3"	"116.2"	"116.6"	"208.2"	"454.1"	"924.3"	"1980.8"	"3350.4"	"4746.9"	"6414.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IYD1"	"Eukaryotic peptide chain release factor GTP-binding subunit ERF3B OS=Homo sapiens OX=9606 GN=GSPT2 PE=1 SV=2"	"9"	"5"	"7"	"1"	"628"	"68.8"	"5.43"	"978.20"	"17.26"	"2"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03143, Pf07145"	"23708"	"ENSG00000189369"	"GSPT2"	"hsa:23708; Q8IYD1; Q9H909; Q9NVY0; Q9NY44"	"Translation factors"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"5"	"0"	"24.0"	"23.3"	"22.5"	"21.0"	"26.1"	"29.6"	"38.3"	"50.9"	"202.0"	"604.5"	"919.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60828"	"Polyglutamine-binding protein 1 OS=Homo sapiens OX=9606 GN=PQBP1 PE=1 SV=1"	"23"	"4"	"7"	"4"	"265"	"30.5"	"6.33"	"1366.84"	"17.24"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	""	"10084"	"ENSG00000102103"	"PQBP1"	"C9JQA1; hsa:10084; O60828; Q4VY25; Q4VY26; Q4VY27; Q4VY29; Q4VY30; Q4VY34; Q4VY35; Q4VY36; Q4VY37; Q4VY38; Q9GZP2; Q9GZU4; Q9GZZ4"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"358.1"	"344.3"	"335.0"	"314.0"	"340.1"	"352.8"	"420.8"	"494.5"	"802.2"	"1406.6"	"1765.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5JSZ5"	"Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2"	"3"	"4"	"7"	"4"	"2229"	"242.8"	"8.34"	"1221.30"	"17.17"	"3"	"4"	"other biological processes"	""	""	"Pf07001"	"84726"	"ENSG00000288701"	"PRRC2B"	"hsa:84726; O60270; Q5JSZ5; Q5JSZ7; Q66VZ2; Q68CR0; Q96EI9; Q9H683"	""	""	"0"	"0"	"169.3"	"167.8"	"170.8"	"165.7"	"178.9"	"170.7"	"201.5"	"243.4"	"329.4"	"393.2"	"521.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12872"	"Splicing factor, suppressor of white-apricot homolog OS=Homo sapiens OX=9606 GN=SFSWAP PE=1 SV=3"	"5"	"4"	"10"	"4"	"951"	"104.8"	"8.05"	"1685.80"	"17.11"	"4"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf01805, Pf09750"	"6433"	"ENSG00000061936"	"SFSWAP"	"B2RN45; B7ZM97; F5H6B8; hsa:6433; Q12872; Q6PJF7"	"mRNA processing"	""	"1"	"0"	"188.5"	"188.7"	"178.3"	"140.0"	"172.0"	"194.0"	"224.9"	"276.0"	"389.0"	"654.2"	"869.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z794"	"Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3"	"7"	"4"	"10"	"1"	"578"	"61.9"	"5.99"	"1701.19"	"17.08"	"4"	"4"	"other biological processes"	"plasma membrane;cytosol;cytoskeleton"	"bone, tooth or skin structural activity"	"Pf00038, Pf16208"	"374454"	"ENSG00000189182"	"KRT77"	"hsa:374454; Q7RTS8; Q7Z794"	""	"Formation of the cornified envelope"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TF01"	"Arginine/serine-rich protein PNISR OS=Homo sapiens OX=9606 GN=PNISR PE=1 SV=2"	"8"	"7"	"12"	"7"	"805"	"92.5"	"10.02"	"2382.98"	"17.05"	"6"	"6"	""	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	""	"Pf15996"	"25957"	"ENSG00000132424"	"PNISR"	"A8K540; E1P5D2; hsa:25957; Q5T064; Q5T065; Q6P2B4; Q6P2N4; Q6PJ93; Q6PK36; Q7Z640; Q8N2L1; Q8TF00; Q8TF01; Q96K10; Q96SI3; Q96SM5; Q9P076; Q9P0C0; Q9Y4N3"	""	""	"0"	"0"	"668.0"	"579.3"	"664.5"	"603.4"	"639.6"	"640.0"	"723.3"	"755.4"	"904.3"	"1109.9"	"1445.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NY12"	"H/ACA ribonucleoprotein complex subunit 1 OS=Homo sapiens OX=9606 GN=GAR1 PE=1 SV=1"	"24"	"5"	"7"	"5"	"217"	"22.3"	"10.92"	"699.88"	"17.04"	"2"	"5"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf04410"	"54433"	"ENSG00000109534"	"GAR1"	"hsa:54433; Q5MJQ2; Q9NY12"	""	"rRNA modification in the nucleus and cytosol; Telomere Extension By Telomerase"	"2"	"0"	"365.0"	"397.0"	"367.8"	"328.2"	"372.0"	"374.8"	"431.2"	"556.0"	"1020.2"	"1895.9"	"2546.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6UX04"	"Spliceosome-associated protein CWC27 homolog OS=Homo sapiens OX=9606 GN=CWC27 PE=1 SV=1"	"11"	"3"	"5"	"3"	"472"	"53.8"	"5.80"	"1027.47"	"17.00"	"2"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf00160"	"10283"	"ENSG00000153015"	"CWC27"	"hsa:10283; O60529; O60530; Q6UX04; Q96EM3"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"238.9"	"199.3"	"254.5"	"249.8"	"266.6"	"261.4"	"299.9"	"287.8"	"423.3"	"681.4"	"951.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14974"	"Protein phosphatase 1 regulatory subunit 12A OS=Homo sapiens OX=9606 GN=PPP1R12A PE=1 SV=1"	"8"	"6"	"9"	"6"	"1030"	"115.2"	"5.40"	"1164.88"	"16.99"	"4"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00023, Pf15898"	"4659"	"ENSG00000058272"	"PPP1R12A"	"B4DZ09; F8VWB4; hsa:4659; O14974; Q2NKL4; Q569H0; Q86WU3; Q8NFR6; Q9BYH0"	"Focal adhesion; Hippo-Merlin signaling dysregulation; Regulation of actin cytoskeleton"	"Regulation of PLK1 Activity at G2/M Transition; RHO GTPases activate CIT; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; RHO GTPases activate PAKs"	"8"	"0"	"231.8"	"185.5"	"281.5"	"239.3"	"233.6"	"245.7"	"287.7"	"318.3"	"578.0"	"1037.5"	"1457.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P67870"	"Casein kinase II subunit beta OS=Homo sapiens OX=9606 GN=CSNK2B PE=1 SV=1"	"23"	"4"	"8"	"4"	"215"	"24.9"	"5.55"	"1596.35"	"16.93"	"4"	"4"	"cell-cell signaling;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;kinase activity;other molecular function"	"Pf01214"	"1460"	"ENSG00000204435; ENSG00000206406; ENSG00000224398; ENSG00000224774; ENSG00000228875; ENSG00000230700; ENSG00000232960"	"CSNK2B"	"B0UXA9; hsa:1460; P07312; P13862; P67870; Q4VX47"	"Alzheimer's disease and miRNA effects; lncRNA in canonical Wnt signaling and colorectal cancer; Breast cancer pathway; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Measles virus infection; Pleural mesothelioma; Alzheimer's disease"	"Condensation of Prometaphase Chromosomes; Neutrophil degranulation; Regulation of PTEN stability and activity; KEAP1-NFE2L2 pathway; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Regulation of TP53 Activity through Phosphorylation; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; WNT mediated activation of DVL; Signal transduction by L1; Receptor Mediated Mitophagy; Synthesis of PC"	"19"	"0"	"385.3"	"310.2"	"359.3"	"363.8"	"419.7"	"279.2"	"450.8"	"580.4"	"775.3"	"1919.3"	"3601.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P20248"	"Cyclin-A2 OS=Homo sapiens OX=9606 GN=CCNA2 PE=1 SV=2"	"12"	"3"	"5"	"3"	"432"	"48.5"	"6.54"	"1070.48"	"16.90"	"2"	"3"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00134, Pf02984, Pf16500"	"890"	"ENSG00000145386"	"CCNA2"	"A8K7B6; hsa:890; P20248; Q2M3U6; Q4W5P4; Q6LER8"	"AMP-activated protein kinase signaling; Cell cycle; Retinoblastoma gene in cancer; IL-18 signaling pathway"	"TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; Regulation of TP53 Degradation; SCF(Skp2)-mediated degradation of p27/p21; Regulation of TP53 Activity through Phosphorylation; G2 Phase; Telomere Extension By Telomerase; Regulation of APC/C activators between G1/S and early anaphase; Senescence-Associated Secretory Phenotype (SASP); Processing of DNA double-strand break ends; DNA Damage/Telomere Stress Induced Senescence; p53-Dependent G1 DNA Damage Response; Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1; Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes"	"24"	"0"	"62.0"	"43.9"	"69.9"	"55.7"	"54.9"	"59.5"	"80.5"	"88.3"	"267.3"	"531.0"	"785.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P57076"	"Cilia- and flagella-associated protein 298 OS=Homo sapiens OX=9606 GN=CFAP298 PE=1 SV=1"	"17"	"3"	"7"	"3"	"290"	"33.2"	"7.44"	"1300.34"	"16.78"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	""	"Pf11069"	"56683"	"ENSG00000159079"	"CFAP298"	"hsa:56683; P57076; Q53FH0"	"Ciliopathies"	""	"1"	"0"	"231.4"	"194.0"	"243.5"	"251.9"	"262.4"	"260.3"	"280.9"	"334.3"	"672.0"	"1233.6"	"1685.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95639"	"Cleavage and polyadenylation specificity factor subunit 4 OS=Homo sapiens OX=9606 GN=CPSF4 PE=1 SV=1"	"21"	"4"	"6"	"4"	"269"	"30.2"	"8.31"	"838.47"	"16.75"	"2"	"4"	""	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00098, Pf00642, Pf15663"	"10898"	"ENSG00000160917"	"CPSF4"	"D6W5S8; hsa:10898; O95639; Q6FGE6; Q86TF8; Q9BTW6"	"mRNA processing"	"Transport of Mature mRNA Derived from an Intronless Transcript; tRNA processing in the nucleus; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs; Inhibition of Host mRNA Processing and RNA Silencing"	"8"	"0"	"244.0"	"253.7"	"219.5"	"217.9"	"242.7"	"161.2"	"277.6"	"402.1"	"578.7"	"880.9"	"1319.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00231"	"26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3"	"16"	"5"	"6"	"5"	"422"	"47.4"	"6.48"	"427.92"	"16.74"	"1"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf01399, Pf18055, Pf18503"	"5717"	"ENSG00000108671"	"PSMD11"	"A8K3I7; E1P663; hsa:5717; O00231; O00495; Q53FT5"	"Proteasome degradation; Parkin-ubiquitin proteasomal system pathway; VEGFA-VEGFR2 signaling"	"Separation of Sister Chromatids; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"63"	"0"	"206.3"	"215.0"	"252.8"	"209.4"	"216.7"	"252.6"	"278.1"	"363.1"	"677.0"	"2079.3"	"4185.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92620"	"Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 OS=Homo sapiens OX=9606 GN=DHX38 PE=1 SV=2"	"5"	"5"	"9"	"4"	"1227"	"140.4"	"6.54"	"1739.42"	"16.73"	"4"	"5"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"9785"	"ENSG00000140829"	"DHX38"	"B4DVG8; D3DWS7; hsa:9785; O75212; Q92620; Q96HN7"	"mRNA processing"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"5"	"0"	"31.6"	"27.3"	"42.9"	"36.3"	"31.2"	"32.9"	"41.6"	"43.2"	"138.4"	"263.7"	"330.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15160"	"DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1"	"16"	"5"	"9"	"5"	"346"	"39.2"	"5.50"	"1588.61"	"16.73"	"4"	"5"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01000, Pf01193"	"9533"	"ENSG00000171453"	"POLR1C"	"hsa:9533; O15160; O75395; Q5JTE3"	"Pyrimidine metabolism; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"15"	"0"	"150.7"	"153.6"	"173.4"	"143.5"	"151.7"	"230.9"	"233.8"	"441.2"	"1259.0"	"2259.3"	"3118.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P10515"	"Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3"	"10"	"5"	"9"	"5"	"647"	"69.0"	"7.84"	"1437.54"	"16.69"	"4"	"5"	"other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf00198, Pf00364, Pf02817"	"1737"	"ENSG00000150768"	"DLAT"	"hsa:1737; P10515; Q16783; Q53EP3"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Neuroinflammation and glutamatergic signaling; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"Glyoxylate metabolism and glycine degradation; Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid"	"8"	"0"	"402.3"	"353.1"	"466.4"	"422.1"	"439.8"	"445.2"	"510.4"	"590.5"	"796.5"	"1204.8"	"1795.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50502"	"Hsc70-interacting protein OS=Homo sapiens OX=9606 GN=ST13 PE=1 SV=2"	"18"	"7"	"12"	"7"	"369"	"41.3"	"5.27"	"2880.02"	"16.68"	"7"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf17830, Pf18253"	"6767"	"ENSG00000100380"	"ST13"	"hsa:6767; O14999; P50502; Q2TU77"	""	"Regulation of HSF1-mediated heat shock response"	"1"	"0"	"698.1"	"818.5"	"870.9"	"823.7"	"883.5"	"656.1"	"1001.3"	"1466.3"	"2127.8"	"2802.3"	"3385.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H2U1"	"ATP-dependent DNA/RNA helicase DHX36 OS=Homo sapiens OX=9606 GN=DHX36 PE=1 SV=2"	"5"	"3"	"6"	"2"	"1008"	"114.7"	"7.68"	"753.00"	"16.64"	"1"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"170506"	"ENSG00000174953"	"DHX36"	"B2RB00; hsa:170506; Q70JU3; Q8IYE5; Q9H2U1; Q9P240"	"VEGFA-VEGFR2 signaling"	"DEx/H-box helicases activate type I IFN and inflammatory cytokines production"	"2"	"0"	"54.7"	"40.0"	"86.0"	"71.8"	"71.8"	"74.0"	"82.3"	"81.9"	"148.6"	"322.5"	"483.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06493"	"Cyclin-dependent kinase 1 OS=Homo sapiens OX=9606 GN=CDK1 PE=1 SV=3"	"15"	"4"	"7"	"3"	"297"	"34.1"	"8.40"	"1294.79"	"16.57"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069"	"983"	"ENSG00000170312"	"CDK1"	"A8K7C4; C9J497; hsa:983; O60764; P06493"	"miRNA regulation of DNA damage response; Cell cycle; Microtubule cytoskeleton regulation; Spinal cord injury; Retinoblastoma gene in cancer; ATM signaling pathway; PPAR-alpha pathway; Nuclear receptors meta-pathway; ATM signaling in development and disease ; G1 to S cell cycle control; Cohesin complex - Cornelia de Lange syndrome; Urotensin-II-mediated signaling pathway; DNA damage response"	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A; MAPK6/MAPK4 signaling; The role of GTSE1 in G2/M progression after G2 checkpoint; Resolution of Sister Chromatid Cohesion; Recruitment of NuMA to mitotic centrosomes; Nuclear Pore Complex (NPC) Disassembly; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Regulation of TP53 Degradation; APC/C:Cdc20 mediated degradation of Cyclin B; Phosphorylation of the APC/C; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Transcriptional regulation by RUNX2; Ovarian tumor domain proteases; MASTL Facilitates Mitotic Progression; E2F-enabled inhibition of pre-replication complex formation; MAPK3 (ERK1) activation; Golgi Cisternae Pericentriolar Stack Reorganization; Condensation of Prophase Chromosomes; G1/S-Specific Transcription; Initiation of Nuclear Envelope (NE) Reformation; Condensation of Prometaphase Chromosomes; Activation of NIMA Kinases NEK9, NEK6, NEK7; G2/M DNA replication checkpoint; Depolymerization of the Nuclear Lamina; Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1; Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes; Phosphorylation of Emi1"	"49"	"0"	"157.0"	"158.5"	"157.8"	"147.9"	"187.5"	"187.1"	"205.4"	"238.3"	"527.4"	"1492.3"	"2222.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35606"	"Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2"	"5"	"3"	"8"	"3"	"906"	"102.4"	"5.27"	"2175.02"	"16.56"	"3"	"3"	"transport"	"other membranes;cytosol;ER/Golgi"	"other molecular function"	"Pf00400, Pf04053"	"9276"	"ENSG00000184432"	"COPB2"	"B4DZI8; hsa:9276; P35606"	""	"COPI-mediated anterograde transport; COPI-dependent Golgi-to-ER retrograde traffic"	"2"	"0"	"151.1"	"153.3"	"139.6"	"130.8"	"151.2"	"155.4"	"177.2"	"230.4"	"399.0"	"668.4"	"1189.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4A5"	"Transformation/transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3"	"2"	"6"	"10"	"6"	"3859"	"437.3"	"8.19"	"1720.43"	"16.56"	"5"	"5"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00454, Pf02259, Pf20175, Pf20206"	"8295"	"ENSG00000196367"	"TRRAP"	"A4D265; hsa:8295; O75218; Q9Y4A5; Q9Y631; Q9Y6H4"	"Rett syndrome causing genes"	"Ub-specific processing proteases; HATs acetylate histones; Formation of the beta-catenin:TCF transactivating complex"	"4"	"0"	"145.6"	"153.6"	"147.6"	"154.9"	"162.3"	"129.3"	"149.4"	"201.6"	"319.6"	"599.4"	"758.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P48735"	"Isocitrate dehydrogenase [NADP], mitochondrial OS=Homo sapiens OX=9606 GN=IDH2 PE=1 SV=2"	"14"	"6"	"11"	"6"	"452"	"50.9"	"8.69"	"2128.77"	"16.54"	"6"	"5"	"other metabolic processes"	"cytosol;mitochondrion;other cytoplasmic organelle"	"other molecular function"	"Pf00180"	"3418"	"ENSG00000182054"	"IDH2"	"B2R6L6; B4DFL2; hsa:3418; P48735; Q96GT3"	"VEGFA-VEGFR2 signaling; Metabolic reprogramming in colon cancer; Cerebral organic acidurias, including diseases; TCA cycle (aka Krebs or citric acid cycle)"	"Transcriptional activation of mitochondrial biogenesis; Citric acid cycle (TCA cycle)"	"6"	"0"	"450.6"	"448.8"	"469.4"	"406.3"	"447.8"	"396.6"	"565.4"	"653.2"	"1030.4"	"1822.1"	"2310.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75821"	"Eukaryotic translation initiation factor 3 subunit G OS=Homo sapiens OX=9606 GN=EIF3G PE=1 SV=2"	"17"	"4"	"6"	"4"	"320"	"35.6"	"6.13"	"813.50"	"16.48"	"2"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf12353"	"8666"	"ENSG00000130811"	"EIF3G"	"hsa:8666; O14801; O75821; Q969U5"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"8"	"0"	"228.4"	"198.8"	"264.0"	"242.5"	"245.5"	"227.5"	"288.7"	"351.0"	"540.3"	"1209.2"	"2869.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5VT52"	"Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1"	"4"	"4"	"7"	"4"	"1461"	"155.9"	"7.42"	"1183.72"	"16.46"	"3"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf04818"	"23248"	"ENSG00000163125"	"RPRD2"	"A8K6N8; B3KPT1; B4E2Q6; hsa:23248; O75048; Q5VT51; Q5VT52; Q5VT53; Q6MZL4; Q86XD2; Q9P0D7"	""	"RNA polymerase II transcribes snRNA genes"	"1"	"0"	"173.1"	"181.0"	"193.4"	"157.3"	"204.4"	"185.6"	"216.0"	"297.8"	"453.0"	"841.9"	"1401.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3B9"	"RRP15-like protein OS=Homo sapiens OX=9606 GN=RRP15 PE=1 SV=2"	"15"	"3"	"6"	"3"	"282"	"31.5"	"5.52"	"709.25"	"16.44"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"other cell component"	""	"Pf07890"	"51018"	"ENSG00000067533"	"RRP15"	"hsa:51018; Q9Y3B9"	""	""	"0"	"0"	"216.1"	"180.3"	"260.5"	"224.4"	"271.1"	"252.3"	"274.6"	"326.3"	"564.4"	"732.0"	"1012.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UPT5"	"Exocyst complex component 7 OS=Homo sapiens OX=9606 GN=EXOC7 PE=1 SV=3"	"8"	"5"	"9"	"5"	"735"	"83.3"	"6.79"	"1902.87"	"16.43"	"5"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf03081"	"23265"	"ENSG00000182473"	"EXOC7"	"B5MC69; B8XXP2; hsa:23265; Q8ND93; Q8WV91; Q96FF0; Q9H8C3; Q9H9X3; Q9HA32; Q9UPT5"	"Angiopoietin-like protein 8 regulatory pathway; Ciliary landscape"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"5"	"0"	"106.6"	"92.5"	"158.1"	"130.0"	"152.2"	"157.7"	"225.6"	"379.3"	"987.1"	"1260.4"	"1484.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15785"	"Mitochondrial import receptor subunit TOM34 OS=Homo sapiens OX=9606 GN=TOMM34 PE=1 SV=2"	"16"	"4"	"8"	"4"	"309"	"34.5"	"8.98"	"1655.85"	"16.41"	"4"	"4"	"cell organization and biogenesis;transport"	"other membranes;cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00515"	"10953"	"ENSG00000025772"	"TOMM34"	"hsa:10953; Q15785; Q53GH9; Q6IBN7; Q9NTZ3"	""	""	"0"	"0"	"212.5"	"134.7"	"247.7"	"216.0"	"228.9"	"215.0"	"253.3"	"310.4"	"595.9"	"1224.9"	"1650.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WWI1"	"LIM domain only protein 7 OS=Homo sapiens OX=9606 GN=LMO7 PE=1 SV=3"	"4"	"6"	"11"	"6"	"1683"	"192.6"	"8.09"	"2000.85"	"16.39"	"6"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00307, Pf00412, Pf00595, Pf15949"	"4008"	"ENSG00000136153"	"LMO7"	"E9PLH4; hsa:4008; O15462; O95346; Q5TBK6; Q8WWI1; Q9UKC1; Q9UQM5; Q9Y6A7"	""	"Antigen processing: Ubiquitination & Proteasome degradation; Neddylation; Signaling by ALK fusions and activated point mutants"	"3"	"0"	"330.5"	"306.6"	"394.4"	"361.0"	"384.8"	"389.6"	"402.9"	"460.9"	"742.3"	"1208.4"	"1594.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99986"	"Serine/threonine-protein kinase VRK1 OS=Homo sapiens OX=9606 GN=VRK1 PE=1 SV=1"	"15"	"5"	"9"	"5"	"396"	"45.4"	"8.91"	"1726.54"	"16.36"	"4"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;ER/Golgi;nucleus"	"kinase activity;other molecular function"	"Pf00069"	"7443"	"ENSG00000100749"	"VRK1"	"hsa:7443; Q3SYL2; Q99986"	""	"Nuclear Envelope Breakdown; Initiation of Nuclear Envelope (NE) Reformation"	"2"	"0"	"1204.9"	"1132.1"	"1206.4"	"1060.5"	"1241.6"	"1177.8"	"1480.2"	"1560.9"	"1482.3"	"1542.0"	"1515.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TAT6"	"Nuclear protein localization protein 4 homolog OS=Homo sapiens OX=9606 GN=NPLOC4 PE=1 SV=3"	"7"	"4"	"7"	"4"	"608"	"68.1"	"6.38"	"2004.51"	"16.32"	"4"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf05020, Pf05021, Pf11543"	"55666"	"ENSG00000182446"	"NPLOC4"	"hsa:55666; Q8N3J1; Q8TAT6; Q9H8V2; Q9H964; Q9NWR5; Q9P229"	""	"Neddylation; KEAP1-NFE2L2 pathway; Translesion Synthesis by POLH"	"3"	"0"	"254.5"	"206.5"	"285.9"	"253.4"	"278.7"	"240.0"	"296.4"	"370.3"	"654.4"	"1816.5"	"2832.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14554"	"Protein disulfide-isomerase A5 OS=Homo sapiens OX=9606 GN=PDIA5 PE=1 SV=1"	"13"	"5"	"10"	"5"	"519"	"59.6"	"7.91"	"2084.59"	"16.31"	"4"	"5"	"protein metabolism;other metabolic processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf00085"	"10954"	"ENSG00000065485"	"PDIA5"	"D3DN95; hsa:10954; Q14554; Q9BV43"	""	"XBP1(S) activates chaperone genes"	"1"	"0"	"182.2"	"178.1"	"182.8"	"159.2"	"185.5"	"192.6"	"263.3"	"446.5"	"832.1"	"854.8"	"803.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62847"	"40S ribosomal protein S24 OS=Homo sapiens OX=9606 GN=RPS24 PE=1 SV=1"	"14"	"3"	"9"	"3"	"133"	"15.4"	"10.78"	"1548.50"	"16.29"	"2"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01282"	"6229"	"ENSG00000138326"	"RPS24"	"E7EPK6; hsa:6229; P16632; P62847; Q5T0P7; Q5T0P8; Q7Z3D1"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"138.8"	"116.6"	"146.0"	"126.5"	"153.7"	"141.2"	"180.9"	"273.3"	"616.3"	"1146.5"	"1819.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKF6"	"Cleavage and polyadenylation specificity factor subunit 3 OS=Homo sapiens OX=9606 GN=CPSF3 PE=1 SV=1"	"8"	"5"	"9"	"5"	"684"	"77.4"	"5.60"	"2049.89"	"16.25"	"5"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00753, Pf07521, Pf10996, Pf11718"	"51692"	"ENSG00000119203"	"CPSF3"	"hsa:51692; O14769; Q53RS2; Q96F36; Q9UKF6"	"mRNA processing"	"Transport of Mature mRNA Derived from an Intronless Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"6"	"0"	"183.4"	"159.1"	"213.3"	"166.6"	"209.6"	"220.3"	"243.5"	"302.3"	"636.3"	"1343.6"	"2276.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86UE4"	"Protein LYRIC OS=Homo sapiens OX=9606 GN=MTDH PE=1 SV=2"	"14"	"5"	"8"	"5"	"582"	"63.8"	"9.32"	"2093.79"	"16.19"	"4"	"4"	"signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf15686"	"92140"	"ENSG00000147649"	"MTDH"	"hsa:92140; Q05DH2; Q52QU9; Q6PK07; Q86UE4; Q8TCX3"	"Gastric cancer network 2; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; CCL18 signaling pathway"	""	"3"	"0"	"459.5"	"364.9"	"454.3"	"431.4"	"443.4"	"472.1"	"537.3"	"634.0"	"1819.9"	"2423.4"	"2494.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13045"	"Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2"	"5"	"5"	"8"	"5"	"1269"	"144.7"	"6.05"	"1434.45"	"16.19"	"4"	"4"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00626, Pf12799, Pf13855"	"2314"	"ENSG00000177731; ENSG00000284571"	"FLII"	"B4DIL0; F5H407; hsa:2314; J3QLG3; Q13045"	"VEGFA-VEGFR2 signaling; Smith-Magenis and Potocki-Lupski syndrome copy number variation"	""	"2"	"0"	"97.2"	"88.1"	"123.4"	"108.0"	"117.5"	"113.9"	"132.0"	"165.3"	"594.9"	"1813.5"	"3152.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96A72"	"Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1"	"30"	"4"	"8"	"4"	"148"	"17.3"	"6.39"	"1721.37"	"16.18"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf02792"	"55110"	"ENSG00000111196"	"MAGOHB"	"hsa:55110; Q96A72"	""	"mRNA Splicing - Major Pathway; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	"6"	"0"	"226.3"	"267.0"	"250.0"	"193.1"	"267.5"	"273.8"	"329.9"	"431.5"	"752.5"	"1804.8"	"3532.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q52LJ0"	"Protein FAM98B OS=Homo sapiens OX=9606 GN=FAM98B PE=1 SV=2"	"10"	"3"	"8"	"2"	"433"	"45.5"	"8.69"	"1584.20"	"16.17"	"3"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf10239"	"283742"	"ENSG00000171262"	"FAM98B"	"A8MUW5; hsa:283742; Q52LJ0; Q8N935"	""	"tRNA processing in the nucleus"	"1"	"0"	"144.2"	"130.6"	"162.6"	"129.4"	"134.6"	"149.5"	"168.0"	"174.6"	"238.7"	"390.4"	"602.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61964"	"WD repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=WDR5 PE=1 SV=1"	"11"	"3"	"8"	"3"	"334"	"36.6"	"8.27"	"1306.50"	"16.10"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00400"	"11091"	"ENSG00000196363"	"WDR5"	"hsa:11091; P61964; Q91VA5; Q9NWX7; Q9UGP9"	"Pleural mesothelioma; Kleefstra syndrome"	"Activation of anterior HOX genes in hindbrain development during early embryogenesis; PKMTs methylate histone lysines; Neddylation; Formation of WDR5-containing histone-modifying complexes; RMTs methylate histone arginines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; HATs acetylate histones; Cardiogenesis"	"10"	"0"	"89.7"	"93.9"	"118.8"	"123.5"	"127.6"	"137.7"	"150.5"	"194.9"	"460.3"	"994.4"	"1472.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H2U2"	"Inorganic pyrophosphatase 2, mitochondrial OS=Homo sapiens OX=9606 GN=PPA2 PE=1 SV=2"	"18"	"4"	"7"	"4"	"334"	"37.9"	"7.39"	"1394.23"	"16.08"	"3"	"4"	"other metabolic processes;other biological processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf00719"	"27068"	"ENSG00000138777"	"PPA2"	"B4DLP7; F8WDN9; hsa:27068; I6L9B6; Q4W5E9; Q6PG51; Q8TBW0; Q96E55; Q9H0T0; Q9H2U2; Q9NX37; Q9P033; Q9ULX0"	""	"Mitochondrial tRNA aminoacylation; Pyrophosphate hydrolysis"	"2"	"0"	"60.0"	"49.0"	"78.2"	"58.3"	"70.8"	"65.6"	"79.7"	"99.2"	"241.4"	"1124.7"	"2719.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UK61"	"Protein TASOR OS=Homo sapiens OX=9606 GN=TASOR PE=1 SV=3"	"3"	"5"	"10"	"5"	"1670"	"188.9"	"5.80"	"1724.95"	"16.07"	"5"	"5"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf12509"	"23272"	"ENSG00000163946"	"TASOR"	"A1L3A4; B5ME28; hsa:23272; Q9H2F7; Q9UK61; Q9UPP7"	""	""	"0"	"0"	"160.6"	"154.1"	"204.6"	"180.6"	"194.1"	"166.9"	"217.4"	"279.6"	"538.8"	"1051.2"	"1466.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96NB3"	"Zinc finger protein 830 OS=Homo sapiens OX=9606 GN=ZNF830 PE=1 SV=2"	"17"	"5"	"8"	"5"	"372"	"42.0"	"5.31"	"1064.58"	"16.06"	"3"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf12874"	"91603"	"ENSG00000198783"	"ZNF830"	"hsa:91603; Q96F60; Q96GZ5; Q96NB3; Q9BU38"	"17q12 copy number variation syndrome"	"mRNA Splicing - Major Pathway; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	"6"	"0"	"335.1"	"328.8"	"379.7"	"318.4"	"328.0"	"324.9"	"385.9"	"458.8"	"709.3"	"1330.5"	"2036.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12800"	"Alpha-globin transcription factor CP2 OS=Homo sapiens OX=9606 GN=TFCP2 PE=1 SV=2"	"7"	"3"	"8"	"3"	"502"	"57.2"	"5.80"	"1574.09"	"15.98"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04516, Pf18016"	"7024"	"ENSG00000135457"	"TFCP2"	"A8K5E9; hsa:7024; Q12800; Q12801; Q9UD75; Q9UD77"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"191.5"	"155.9"	"193.4"	"182.6"	"218.3"	"181.5"	"250.3"	"521.9"	"1972.0"	"3240.8"	"3350.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75822"	"Eukaryotic translation initiation factor 3 subunit J OS=Homo sapiens OX=9606 GN=EIF3J PE=1 SV=2"	"25"	"4"	"6"	"4"	"258"	"29.0"	"4.83"	"1288.85"	"15.97"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf08597"	"8669"	"ENSG00000104131"	"EIF3J"	"B4DUI3; F5H425; hsa:8669; O75822; Q9BUD2; Q9H8Q2; Q9UI65"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"8"	"0"	"99.3"	"75.1"	"123.7"	"111.5"	"101.4"	"118.6"	"131.6"	"128.6"	"330.9"	"2453.4"	"3783.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86YS7"	"C2 domain-containing protein 5 OS=Homo sapiens OX=9606 GN=C2CD5 PE=1 SV=1"	"5"	"5"	"11"	"5"	"1000"	"110.4"	"5.69"	"2006.98"	"15.96"	"5"	"5"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00168"	"9847"	"ENSG00000111731"	"C2CD5"	"B4DJ03; B4DRN7; B7ZLL0; F5H2A1; F5H5R1; hsa:9847; O60280; Q17RY7; Q7Z619; Q86SU3; Q86YS7"	""	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"	"1"	"0"	"90.0"	"85.6"	"100.2"	"106.8"	"133.8"	"312.1"	"708.5"	"1244.4"	"1702.1"	"1957.9"	"1841.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75390"	"Citrate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=CS PE=1 SV=2"	"12"	"6"	"12"	"6"	"466"	"51.7"	"8.32"	"2274.38"	"15.95"	"6"	"5"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00285"	"1431"	"ENSG00000062485"	"CS"	"hsa:1431; O75390; Q71UT9; Q7KZH0; Q96FZ8; Q9BWN8"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Fluoroacetic acid toxicity; TCA cycle (aka Krebs or citric acid cycle)"	"Citric acid cycle (TCA cycle); Mitochondrial protein import"	"6"	"0"	"844.1"	"775.7"	"896.5"	"742.2"	"821.6"	"862.4"	"1037.0"	"1067.8"	"1419.2"	"2360.4"	"4020.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92688"	"Acidic leucine-rich nuclear phosphoprotein 32 family member B OS=Homo sapiens OX=9606 GN=ANP32B PE=1 SV=1"	"16"	"4"	"11"	"3"	"251"	"28.8"	"4.06"	"1913.93"	"15.93"	"4"	"3"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf12799"	"10541"	"ENSG00000136938"	"ANP32B"	"B2R9C7; hsa:10541; O00655; P78458; P78459; Q92688"	""	""	"0"	"0"	"318.0"	"328.0"	"313.5"	"302.3"	"331.3"	"357.2"	"357.8"	"471.7"	"921.9"	"1493.4"	"2278.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6N069"	"N-alpha-acetyltransferase 16, NatA auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA16 PE=1 SV=2"	"5"	"4"	"8"	"2"	"864"	"101.4"	"7.87"	"963.41"	"15.92"	"3"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity"	"Pf07719, Pf12569"	"79612"	"ENSG00000172766"	"NAA16"	"B0QZ59; hsa:79612; Q5VSP9; Q6N069; Q6P2D5; Q8N5J3; Q8N870"	""	""	"0"	"0"	"38.2"	"40.6"	"50.6"	"35.9"	"52.1"	"43.3"	"53.1"	"81.4"	"340.2"	"786.0"	"1145.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q09161"	"Nuclear cap-binding protein subunit 1 OS=Homo sapiens OX=9606 GN=NCBP1 PE=1 SV=1"	"10"	"6"	"11"	"6"	"790"	"91.8"	"6.43"	"2176.12"	"15.91"	"5"	"5"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02854, Pf09088, Pf09090"	"4686"	"ENSG00000136937"	"NCBP1"	"B2R718; hsa:4686; Q09161; Q59G76; Q5T1V0; Q5T7X2"	"mRNA processing; 3q29 copy number variation syndrome"	"mRNA Splicing - Major Pathway; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; RNA polymerase II transcribes snRNA genes; Processing of Intronless Pre-mRNAs; Transport of Mature mRNA derived from an Intron-Containing Transcript; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; snRNP Assembly; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Abortive elongation of HIV-1 transcript in the absence of Tat; RNA Polymerase II Pre-transcription Events; mRNA Capping; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Signaling by FGFR2 IIIa TM; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"29"	"0"	"247.8"	"274.0"	"298.8"	"235.3"	"285.7"	"276.7"	"330.2"	"445.2"	"699.4"	"1481.6"	"2326.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96A33"	"Coiled-coil domain-containing protein 47 OS=Homo sapiens OX=9606 GN=CCDC47 PE=1 SV=1"	"13"	"4"	"7"	"4"	"483"	"55.8"	"4.87"	"958.70"	"15.91"	"3"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;other cell component"	"translation activity;other molecular function"	"Pf07946"	"57003"	"ENSG00000108588"	"CCDC47"	"B2RAS8; D3DU20; hsa:57003; Q96A33; Q96D00; Q96JZ7; Q9H3E4; Q9NRG3"	""	""	"0"	"0"	"243.0"	"185.5"	"250.7"	"228.9"	"253.4"	"259.4"	"276.7"	"334.3"	"779.0"	"1855.8"	"2945.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WWM7"	"Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2"	"7"	"4"	"7"	"4"	"1075"	"113.3"	"8.59"	"1105.50"	"15.86"	"3"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf06741, Pf07145, Pf14438"	"11273"	"ENSG00000168488"	"ATXN2L"	"A8K1R6; B9EGM2; E9PAR9; hsa:11273; O95135; Q63ZY4; Q6NVJ8; Q6PJW6; Q8IU61; Q8IU95; Q8WWM3; Q8WWM4; Q8WWM5; Q8WWM6; Q8WWM7; Q99703"	"16p11.2 distal deletion syndrome"	""	"1"	"0"	"72.8"	"53.9"	"83.7"	"77.4"	"75.9"	"78.4"	"91.7"	"92.4"	"147.0"	"217.9"	"291.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96F07"	"Cytoplasmic FMR1-interacting protein 2 OS=Homo sapiens OX=9606 GN=CYFIP2 PE=1 SV=2"	"5"	"5"	"9"	"1"	"1278"	"148.3"	"7.31"	"1505.04"	"15.85"	"4"	"5"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf05994, Pf07159"	"26999"	"ENSG00000055163"	"CYFIP2"	"A6NLT2; D3DQJ3; hsa:26999; Q53EN5; Q96F07; Q9NTK4; Q9ULQ2; Q9UN29"	"Fragile X syndrome; Regulation of actin cytoskeleton"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RAC1 GTPase cycle; RHO GTPases Activate WASPs and WAVEs; VEGFA-VEGFR2 Pathway"	"7"	"0"	"18.3"	"20.0"	"25.1"	"22.6"	"24.5"	"22.9"	"25.5"	"40.4"	"259.8"	"338.5"	"457.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15020"	"Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1"	"7"	"5"	"7"	"5"	"963"	"109.9"	"5.57"	"802.29"	"15.85"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00076, Pf05391, Pf16605"	"9733"	"ENSG00000075856"	"SART3"	"A8K2E4; B7ZKM0; hsa:9733; Q15020; Q2M2H0; Q58F06; Q8IUS1; Q96J95"	""	""	"0"	"0"	"710.4"	"622.2"	"685.3"	"601.7"	"637.0"	"670.2"	"770.3"	"829.3"	"990.1"	"1380.8"	"1963.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61289"	"Proteasome activator complex subunit 3 OS=Homo sapiens OX=9606 GN=PSME3 PE=1 SV=1"	"26"	"6"	"9"	"6"	"254"	"29.5"	"5.95"	"1547.09"	"15.83"	"4"	"5"	"cell cycle OR cell proliferation;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02251, Pf02252"	"10197"	"ENSG00000131467"	"PSME3"	"A8K9A3; hsa:10197; O35563; P61289; P97373; Q12920; Q13172; Q9BQD9"	"Proteasome degradation"	"ER-Phagosome pathway; Regulation of expression of SLITs and ROBOs; Separation of Sister Chromatids; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"60"	"0"	"229.1"	"228.2"	"272.9"	"252.4"	"294.3"	"276.4"	"348.6"	"466.3"	"993.9"	"2780.2"	"4889.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3C6"	"Peptidyl-prolyl cis-trans isomerase-like 1 OS=Homo sapiens OX=9606 GN=PPIL1 PE=1 SV=1"	"36"	"5"	"11"	"5"	"166"	"18.2"	"7.99"	"2273.38"	"15.82"	"5"	"5"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes"	"nucleus"	"other molecular function"	"Pf00160"	"51645"	"ENSG00000137168"	"PPIL1"	"hsa:51645; O15001; Q5TDC9; Q9Y3C6"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"462.9"	"440.3"	"452.8"	"374.3"	"417.9"	"444.8"	"551.6"	"761.5"	"1076.3"	"1924.5"	"3372.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13310"	"Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1"	"8"	"4"	"7"	"1"	"644"	"70.7"	"9.26"	"1148.26"	"15.81"	"3"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf00658"	"8761"	"ENSG00000090621"	"PABPC4"	"B1ANQ8; hsa:8761; Q13310; Q4VC03; Q6P0N3"	""	""	"0"	"0"	"47.2"	"43.9"	"51.9"	"42.0"	"55.7"	"50.0"	"66.1"	"77.2"	"107.1"	"209.9"	"333.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62875"	"DNA-directed RNA polymerases I, II, and III subunit RPABC5 OS=Homo sapiens OX=9606 GN=POLR2L PE=1 SV=1"	"73"	"4"	"5"	"4"	"67"	"7.6"	"7.77"	"471.89"	"15.80"	"1"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01194"	"5441"	"ENSG00000177700"	"POLR2L"	"hsa:5441; P52436; P62875; Q6FHX3"	"Pyrimidine metabolism; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"mRNA Splicing - Major Pathway; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; B-WICH complex positively regulates rRNA expression; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"56"	"0"	"113.8"	"118.7"	"115.6"	"116.6"	"124.1"	"109.4"	"150.3"	"230.9"	"518.7"	"908.4"	"1339.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23528"	"Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3"	"32"	"4"	"8"	"4"	"166"	"18.5"	"8.09"	"1742.50"	"15.76"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf00241"	"1072"	"ENSG00000172757"	"CFL1"	"B3KUQ1; hsa:1072; P23528; Q53Y87; Q9UCA2"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; VEGFA-VEGFR2 signaling; EGF/EGFR signaling pathway; Envelope proteins and their potential roles in EDMD physiopathology; 7q11.23 copy number variation syndrome; Neuroinflammation and glutamatergic signaling; CCL18 signaling pathway; Regulation of actin cytoskeleton; G13 signaling pathway"	"Platelet degranulation ; Regulation of actin dynamics for phagocytic cup formation; EPHB-mediated forward signaling; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Sema3A PAK dependent Axon repulsion; RHO GTPases Activate ROCKs"	"15"	"0"	"289.8"	"301.4"	"319.1"	"299.9"	"299.7"	"236.0"	"330.0"	"463.4"	"766.4"	"1290.1"	"1878.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13425"	"Beta-2-syntrophin OS=Homo sapiens OX=9606 GN=SNTB2 PE=1 SV=1"	"9"	"4"	"11"	"4"	"540"	"57.9"	"8.82"	"2402.24"	"15.75"	"4"	"4"	""	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00595, Pf18012"	"6645"	"ENSG00000168807"	"SNTB2"	"hsa:6645; Q13425; Q9BY09"	""	""	"0"	"0"	"436.4"	"399.5"	"482.9"	"422.7"	"443.2"	"470.0"	"544.6"	"677.4"	"1246.5"	"2088.1"	"2649.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55769"	"NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3"	"54"	"5"	"7"	"5"	"128"	"14.2"	"8.46"	"1072.88"	"15.72"	"3"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01248"	"4809"	"ENSG00000100138"	"SNU13"	"hsa:4809; P55769"	"mRNA processing"	"mRNA Splicing - Major Pathway; Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"4"	"0"	"122.9"	"134.6"	"151.7"	"108.4"	"127.7"	"96.3"	"174.0"	"279.5"	"651.3"	"1028.0"	"1127.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14011"	"Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1"	"33"	"4"	"7"	"4"	"172"	"18.6"	"9.51"	"1038.92"	"15.72"	"3"	"4"	"cell organization and biogenesis;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"1153"	"ENSG00000099622"	"CIRBP"	"B3KT17; B4E2X2; hsa:1153; Q14011"	""	""	"0"	"0"	"472.4"	"462.3"	"432.2"	"389.6"	"425.4"	"451.6"	"500.8"	"519.8"	"572.5"	"784.0"	"1194.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6IBS0"	"Twinfilin-2 OS=Homo sapiens OX=9606 GN=TWF2 PE=1 SV=2"	"15"	"4"	"6"	"3"	"349"	"39.5"	"6.84"	"760.58"	"15.72"	"2"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00241"	"11344"	"ENSG00000247596"	"TWF2"	"hsa:11344; Q6IBS0; Q9Y3F5"	""	"Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea"	"2"	"1"	"167.6"	"118.1"	"172.2"	"151.5"	"158.6"	"174.2"	"186.2"	"215.6"	"726.8"	"1864.0"	"2658.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14CX7"	"N-alpha-acetyltransferase 25, NatB auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA25 PE=1 SV=1"	"5"	"5"	"10"	"5"	"972"	"112.2"	"6.64"	"1707.41"	"15.71"	"5"	"5"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;other cell component"	""	"Pf09797"	"80018"	"ENSG00000111300"	"NAA25"	"A0JLU7; hsa:80018; Q14CX7; Q6MZH1; Q7Z4N6; Q9H911"	""	""	"0"	"0"	"81.5"	"136.4"	"101.6"	"118.6"	"133.1"	"134.4"	"210.0"	"517.3"	"1144.9"	"1754.5"	"1770.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H0G5"	"Nuclear speckle splicing regulatory protein 1 OS=Homo sapiens OX=9606 GN=NSRP1 PE=1 SV=1"	"8"	"5"	"10"	"5"	"558"	"66.4"	"8.84"	"1746.83"	"15.70"	"5"	"5"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf09745, Pf20427"	"84081"	"ENSG00000126653"	"NSRP1"	"hsa:84081; Q6FI71; Q9H0G5"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"321.1"	"251.8"	"304.8"	"294.6"	"297.6"	"320.9"	"359.5"	"403.8"	"852.5"	"1349.1"	"1864.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P98179"	"RNA-binding protein 3 OS=Homo sapiens OX=9606 GN=RBM3 PE=1 SV=1"	"22"	"3"	"7"	"3"	"157"	"17.2"	"8.91"	"720.50"	"15.69"	"1"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"translation activity"	"Pf00076"	"5935"	"ENSG00000102317"	"RBM3"	"hsa:5935; P98179"	""	""	"0"	"0"	"205.4"	"501.1"	"89.3"	"109.7"	"123.5"	"140.2"	"237.7"	"381.3"	"319.2"	"558.7"	"747.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63167"	"Dynein light chain 1, cytoplasmic OS=Homo sapiens OX=9606 GN=DYNLL1 PE=1 SV=1"	"34"	"3"	"6"	"3"	"89"	"10.4"	"7.40"	"673.30"	"15.67"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01221"	"8655"	"ENSG00000088986"	"DYNLL1"	"hsa:8655; P63167; Q15701"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein; Genes related to primary cilium development (based on CRISPR); 3q29 copy number variation syndrome"	"MHC class II antigen presentation; COPI-mediated anterograde transport; Neutrophil degranulation; HCMV Early Events; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-independent Golgi-to-ER retrograde traffic; Aggrephagy; Intraflagellar transport; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Recruitment of NuMA to mitotic centrosomes; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Macroautophagy; Activation of BIM and translocation to mitochondria"	"27"	"0"	"622.7"	"702.2"	"709.9"	"658.2"	"777.5"	"622.8"	"802.1"	"885.5"	"1122.8"	"1786.1"	"2684.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UPY6"	"Wiskott-Aldrich syndrome protein family member 3 OS=Homo sapiens OX=9606 GN=WASF3 PE=1 SV=2"	"5"	"2"	"8"	"1"	"502"	"55.3"	"6.43"	"1920.78"	"15.63"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02205"	"10810"	"ENSG00000132970"	"WASF3"	"hsa:10810; O94974; Q86VQ2; Q9UPY6"	""	"Regulation of actin dynamics for phagocytic cup formation; VEGFA-VEGFR2 Pathway; FCGR3A-mediated phagocytosis; RAC1 GTPase cycle; RHO GTPases Activate WASPs and WAVEs"	"5"	"1"	"45.9"	"47.7"	"46.2"	"38.8"	"49.5"	"46.1"	"54.9"	"97.5"	"192.5"	"315.7"	"353.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95400"	"CD2 antigen cytoplasmic tail-binding protein 2 OS=Homo sapiens OX=9606 GN=CD2BP2 PE=1 SV=1"	"21"	"5"	"8"	"5"	"341"	"37.6"	"4.61"	"1835.21"	"15.62"	"4"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf02213"	"10421"	"ENSG00000169217"	"CD2BP2"	"B2RDX2; hsa:10421; O95400; Q9ULP2"	"mRNA processing; Ciliary landscape"	""	"2"	"0"	"128.4"	"140.8"	"171.4"	"117.6"	"138.0"	"149.9"	"178.1"	"231.0"	"401.7"	"1236.2"	"2192.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TEA8"	"D-aminoacyl-tRNA deacylase 1 OS=Homo sapiens OX=9606 GN=DTD1 PE=1 SV=2"	"29"	"2"	"2"	"2"	"209"	"23.4"	"8.24"	""	"15.60"	""	"2"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02580"	"92675"	"ENSG00000125821"	"DTD1"	"A8K5X5; D3DW37; hsa:92675; Q496D1; Q5W184; Q8TEA8; Q8WXU8; Q9BW67; Q9H464; Q9H474"	""	""	"0"	"0"	"20.6"	"25.1"	"30.7"	"30.1"	"25.7"	"26.3"	"44.3"	"77.0"	"242.2"	"469.0"	"518.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43447"	"Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1"	"28"	"5"	"10"	"5"	"177"	"19.2"	"8.07"	"1946.22"	"15.59"	"4"	"5"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00160"	"10465"	"ENSG00000171960"	"PPIH"	"A6NNE7; hsa:10465; O43447"	""	"mRNA Splicing - Major Pathway; SARS-CoV-1 activates/modulates innate immune responses"	"2"	"0"	"640.0"	"564.7"	"697.4"	"667.5"	"678.0"	"672.6"	"859.8"	"1180.5"	"1654.8"	"2364.7"	"3563.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49790"	"Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2"	"5"	"5"	"9"	"5"	"1475"	"153.8"	"8.73"	"2164.33"	"15.58"	"5"	"4"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00641, Pf08604, Pf10599"	"9972"	"ENSG00000124789"	"NUP153"	"B4DIK2; E7EPX5; F6QR24; hsa:9972; P49790; Q4LE47; Q5T9I7; Q7Z743"	""	"Nuclear import of Rev protein; HCMV Late Events; HCMV Early Events; Transcriptional regulation by small RNAs; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"28"	"0"	"279.6"	"234.4"	"320.7"	"251.4"	"281.7"	"308.2"	"335.0"	"415.9"	"644.7"	"949.6"	"1369.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62280"	"40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3"	"38"	"6"	"10"	"6"	"158"	"18.4"	"10.30"	"1841.57"	"15.52"	"5"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00366, Pf16205"	"6205"	"ENSG00000142534"	"RPS11"	"B2R4F5; hsa:6205; P04643; P62280; Q498Y6; Q6IRY0"	"VEGFA-VEGFR2 signaling; IL-18 signaling pathway; Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"21"	"0"	"1051.5"	"834.6"	"1063.0"	"926.3"	"947.6"	"975.9"	"1152.6"	"1327.0"	"1747.9"	"2625.7"	"4062.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07311"	"Acylphosphatase-1 OS=Homo sapiens OX=9606 GN=ACYP1 PE=1 SV=2"	"44"	"4"	"6"	"4"	"99"	"11.3"	"9.31"	"725.22"	"15.45"	"2"	"4"	"other metabolic processes"	""	"other molecular function"	"Pf00708"	"97"	"ENSG00000119640"	"ACYP1"	"A6NDV8; B2R590; hsa:97; P07311"	""	""	"0"	"0"	"105.5"	"77.7"	"119.5"	"111.7"	"131.9"	"121.6"	"160.9"	"276.3"	"720.3"	"1223.7"	"1556.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HAW4"	"Claspin OS=Homo sapiens OX=9606 GN=CLSPN PE=1 SV=3"	"6"	"6"	"11"	"6"	"1339"	"151.0"	"4.82"	"2089.28"	"15.43"	"6"	"5"	"cell cycle OR cell proliferation;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"ER/Golgi;nucleus"	"nucleic acid binding activity;other molecular function"	""	"63967"	"ENSG00000092853"	"CLSPN"	"A6NFL4; hsa:63967; Q1RMC6; Q2KHM3; Q5VYG0; Q6P6H5; Q8IWI1; Q9HAW4"	""	"Ub-specific processing proteases; Activation of ATR in response to replication stress; Processing of DNA double-strand break ends; Apoptotic cleavage of cellular proteins"	"4"	"0"	"318.6"	"214.1"	"326.4"	"304.9"	"305.6"	"272.0"	"336.5"	"380.8"	"846.9"	"680.0"	"936.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99590"	"Protein SCAF11 OS=Homo sapiens OX=9606 GN=SCAF11 PE=1 SV=2"	"5"	"6"	"10"	"5"	"1463"	"164.6"	"8.41"	"2522.01"	"15.42"	"6"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	""	"9169"	"ENSG00000139218"	"SCAF11"	"A6NEU9; A6NLW5; hsa:9169; Q8IW59; Q99590"	"Apoptosis"	""	"1"	"1"	"743.8"	"625.2"	"678.2"	"617.8"	"670.5"	"697.5"	"875.5"	"1111.2"	"1623.7"	"2145.9"	"2456.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00422"	"Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1"	"44"	"8"	"13"	"8"	"153"	"17.6"	"9.35"	"2728.69"	"15.40"	"7"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf06487"	"10284"	"ENSG00000150459"	"SAP18"	"B2R494; hsa:10284; O00422; Q2TTR4; Q6IAW9; Q8N606; Q9UF14; X6RAL5"	"Hedgehog signaling pathway"	"Potential therapeutics for SARS; HDACs deacetylate histones; NoRC negatively regulates rRNA expression; mRNA Splicing - Major Pathway"	"5"	"0"	"1713.1"	"1312.4"	"1651.0"	"1480.6"	"1678.1"	"1635.3"	"1873.6"	"2119.8"	"2481.0"	"3110.9"	"4518.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P27635"	"60S ribosomal protein L10 OS=Homo sapiens OX=9606 GN=RPL10 PE=1 SV=4"	"24"	"3"	"5"	"3"	"214"	"24.6"	"10.08"	"789.96"	"15.39"	"2"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00252"	"100137264; 100146244; 100172946; 100415355; 100468790; 100724614; 100982236; 101083663; 101136536; 101344695; 101444008; 101539056; 101690567; 101867181; 101975002; 102028809; 102257301; 102442647; 102878669; 102890423; 102923570; 102957760; 103127392; 103211225; 103250904; 103731218; 104667036; 104872587; 105294701; 105302495; 105467951; 105521640; 105579731; 105727260; 105824536; 105867804; 106000161; 107160308; 108513162; 108518769; 109696857; 110954; 465944; 700795; 81764"	"ENSAMEG00000000227; ENSANAG00000036053; ENSCAFG00020009114; ENSCAFG00030015144; ENSCAFG00040021422; ENSCAFG00845028627; ENSCANG00000032226; ENSCATG00000030970; ENSCCAG00000024992; ENSCGRG00001008387; ENSCJAG00000011822; ENSCLAG00000003108; ENSCPOG00000002355; ENSECAG00000017154; ENSFCAG00000011395; ENSGGOG00000000131; ENSLCNG00005021252; ENSMFAG00000040824; ENSMLUG00000014337; ENSMMMG00000014279; ENSMMUG00000005494; ENSMNEG00000038094; ENSMPUG00000009320; ENSMUSG00000008682; ENSMUSG00000058443; ENSNGAG00000023746; ENSNLEG00000028143; ENSNVIG00000023818; ENSPANG00000008309; ENSPCOG00000027122; ENSPPAG00000034160; ENSPPYG00000020874; ENSPSMG00000015404; ENSPTIG00000005599; ENSPTRG00000043378; ENSRBIG00000042996; ENSRNOG00000056765; ENSRROG00000019247; ENSSSUG00005010590; ENSSTOG00000011857; ENSTGEG00000012563; ENSUAMG00000020454; ENSUMAG00000019583; ENSUPAG00010000252"	"LOC100768740; LOC101344695; LOC105294701; LOC112632580; Rpl10; RPL10"	"A0A091D943; A0A1S3APJ4; A0A1S3GPT7; A0A1U7SU42; A0A250YCK6; A0A286XQR8; A0A2I3FV08; A0A2J8IN69; A0A2J8RLU6; A0A2K5EV78; A0A2K5ILK8; A0A2K5LLF2; A0A2K5QER4; A0A2K5U275; A0A2K6D043; A0A2K6GRP4; A0A2K6MTH0; A0A2K6NK39; A0A2R9B361; A0A2Y9G5G6; A0A384DKX1; A0A3Q0CF07; A0A3Q7NJC4; A0A452S2Z9; A0A485PEW4; A0A667IJV2; A0A673U4F8; A0A6D2WIN2; A0A6D2XTB8; A0A6I9ME29; A0A6J0A9X4; A0A6J2E7G1; A0A6J3GU06; A0A6P3QFP2; A0A6P5P1X6; A0A6P6DLY1; A0A7J7YFN8; A0A7J8J7V5; A0A822A0T4; A0A8B7B976; A0A8B7FW91; A0A8C0K7J7; A0A8C0TBM4; A0A8C2LMI8; A0A8C2UVN1; A0A8C5ZPE8; A0A8C6S1T7; A0A8C7BXJ2; A0A8C8ZPD3; A0A8C9J452; A0A8D2F5T2; A0A8D2GF85; A0A8I3PXJ3; A0A8J8XDM4; A0A8M1M1S6; A0A9B0U593; A2AM97; A6KRS1; A9CB60; aju:106987320; aml:100468790; B0KWW6; B1MTV1; B3RFD9; C3PT02; cang:105521640; caty:105579731; ccan:109696857; cpoc:100724614; csyr:103250904; D3YC00; dnm:101444008; dord:106000161; ecb:100146244; F7AYR2; F7GKJ8; fca:101083663; G1PPT9; G2HFW2; G3S9Q9; G7Q3B3; ggo:101136536; H2PX84; I2CYS4; I3MI39; L5KDV0; L8Y8T7; M3WF14; M3YD39; mcal:110286529; mcc:700795; mcf:101867181; mlf:102442647; mmu:110954; mmur:105867804; mni:105467951; mpuf:101690567; myb:102257301; nsu:110578606; P45634; pale:102878669; pale:102890423; panu:100137264; pcoq:105824536; pps:100982236; ptg:102957760; ptr:465944; pvp:105294701; pvp:105302495; Q569M8; Q5M9K8; Q6PDV7; Q6ZWV3; rbb:108513162; rbb:108518769; rno:81764; rro:104667036; S7NR49; sara:101539056; tmu:101344695; umr:103679662; zca:113931110"	"Cytoplasmic ribosomal proteins"	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; SRP-dependent cotranslational protein targeting to membrane; Major pathway of rRNA processing in the nucleolus and cytosol; L13a-mediated translational silencing of Ceruloplasmin expression; SRP-dependent cotranslational protein targeting to membrane; Major pathway of rRNA processing in the nucleolus and cytosol; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	"15"	"0"	"118.8"	"132.1"	"151.1"	"133.3"	"160.4"	"120.1"	"166.0"	"218.0"	"340.3"	"564.8"	"987.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBW8"	"COP9 signalosome complex subunit 7a OS=Homo sapiens OX=9606 GN=COPS7A PE=1 SV=1"	"19"	"4"	"8"	"4"	"275"	"30.3"	"8.22"	"1615.46"	"15.38"	"4"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf01399, Pf18392"	"50813"	"ENSG00000111652"	"COPS7A"	"A8K9A6; hsa:50813; Q9NVX3; Q9UBW8; Q9UJW4"	"Ciliary landscape"	"Cargo recognition for clathrin-mediated endocytosis; Neddylation; Formation of TC-NER Pre-Incision Complex; DNA Damage Recognition in GG-NER"	"5"	"0"	"61.3"	"43.3"	"65.8"	"54.4"	"70.2"	"62.5"	"103.3"	"150.4"	"325.6"	"683.7"	"1292.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q0ZGT2"	"Nexilin OS=Homo sapiens OX=9606 GN=NEXN PE=1 SV=1"	"4"	"3"	"8"	"3"	"675"	"80.6"	"5.33"	"1558.94"	"15.36"	"3"	"3"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf07679"	"91624"	"ENSG00000162614"	"NEXN"	"A0PJ84; B4DPZ7; hsa:91624; Q0D2H2; Q0ZGT2; Q14CC2; Q14CC3; Q16081; Q7Z2X0; Q96DL0; Q9Y2V1"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"58.6"	"48.3"	"74.9"	"62.6"	"62.1"	"62.6"	"66.2"	"75.3"	"128.9"	"206.4"	"413.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09493"	"Tropomyosin alpha-1 chain OS=Homo sapiens OX=9606 GN=TPM1 PE=1 SV=2"	"21"	"5"	"10"	"3"	"284"	"32.7"	"4.74"	"1856.71"	"15.35"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00261"	"7168"	"ENSG00000140416"	"TPM1"	"B7Z5T7; D9YZV2; D9YZV3; D9YZV8; hsa:7168; P09493; P09494; P10469; Q6DV89; Q6DV90; Q7Z6L8; Q86W64; Q96IK2; Q9UCI1; Q9UCI2; Q9UCY9; Q9Y427"	"Vitamin D receptor pathway; Striated muscle contraction pathway"	"Smooth Muscle Contraction; Striated Muscle Contraction"	"4"	"2"	"264.4"	"261.6"	"361.5"	"291.0"	"294.1"	"270.8"	"350.7"	"412.9"	"817.7"	"2367.6"	"3685.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P78344"	"Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1"	"7"	"5"	"9"	"5"	"907"	"102.3"	"7.14"	"1506.85"	"15.29"	"4"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus"	"nucleic acid binding activity"	"Pf02020, Pf02847, Pf02854"	"1982"	"ENSG00000110321"	"EIF4G2"	"hsa:1982; O60877; P78344; P78404; Q0VH00; Q0VH01; Q2NKW9; Q49A79; Q53EU1; Q58EZ2; Q8NI71; Q96C16"	"VEGFA-VEGFR2 signaling; Exercise-induced circadian regulation; Acute viral myocarditis"	"ISG15 antiviral mechanism"	"4"	"0"	"278.9"	"200.8"	"332.5"	"297.9"	"354.2"	"339.6"	"334.8"	"431.6"	"670.1"	"1153.2"	"1679.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96A65"	"Exocyst complex component 4 OS=Homo sapiens OX=9606 GN=EXOC4 PE=1 SV=1"	"4"	"4"	"10"	"4"	"974"	"110.4"	"6.49"	"1744.75"	"15.28"	"4"	"4"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf04048"	"60412"	"ENSG00000131558"	"EXOC4"	"E9PED2; hsa:60412; Q541U8; Q96A65; Q9C0G4; Q9H9K0; Q9P102"	"Ciliary landscape"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"4"	"0"	"182.4"	"149.2"	"214.5"	"189.8"	"203.2"	"205.2"	"269.1"	"523.2"	"1464.7"	"1733.9"	"1858.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15514"	"DNA-directed RNA polymerase II subunit RPB4 OS=Homo sapiens OX=9606 GN=POLR2D PE=1 SV=1"	"45"	"5"	"7"	"5"	"142"	"16.3"	"4.79"	"952.33"	"15.27"	"3"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf03874"	"5433"	"ENSG00000144231"	"POLR2D"	"hsa:5433; O15514; Q52LT4"	"Pyrimidine metabolism"	"Transcriptional regulation by small RNAs; Viral Messenger RNA Synthesis; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; mRNA Splicing - Major Pathway; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"42"	"0"	"333.0"	"293.9"	"384.3"	"304.7"	"388.1"	"376.1"	"450.6"	"546.9"	"670.6"	"786.5"	"975.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y678"	"Coatomer subunit gamma-1 OS=Homo sapiens OX=9606 GN=COPG1 PE=1 SV=1"	"6"	"4"	"10"	"4"	"874"	"97.7"	"5.47"	"1860.43"	"15.26"	"4"	"4"	"transport;other biological processes"	"other membranes;cytosol;ER/Golgi"	"other molecular function"	"Pf01602, Pf08752, Pf16381"	"22820"	"ENSG00000181789"	"COPG1"	"A8K6M8; B3KMF6; hsa:22820; Q54AC4; Q9Y678"	"VEGFA-VEGFR2 signaling"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport"	"3"	"0"	"416.1"	"406.7"	"381.2"	"358.9"	"392.7"	"361.7"	"394.0"	"475.4"	"669.0"	"1022.6"	"1555.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15530"	"3-phosphoinositide-dependent protein kinase 1 OS=Homo sapiens OX=9606 GN=PDPK1 PE=1 SV=1"	"6"	"2"	"6"	"2"	"556"	"63.1"	"7.36"	"1602.73"	"15.26"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069, Pf14593"	"5170"	"ENSG00000140992"	"PDPK1"	"H0Y4Z0; hsa:5170; O15530; Q59EH6; Q6FI20; Q8IV52; Q9BRD5"	"MicroRNAs in cardiomyocyte hypertrophy; Integrin-mediated cell adhesion; Thyroid stimulating hormone (TSH) signaling pathway; Glioblastoma signaling pathways; B cell receptor signaling pathway; Interleukin-11 signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Cardiac hypertrophic response; Focal adhesion; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Leptin-insulin signaling overlap; PPAR signaling pathway; Endometrial cancer; PI3K-Akt signaling pathway; EGF/EGFR signaling pathway; Head and neck squamous cell carcinoma; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; Modulators of TCR signaling and T cell activation; GDNF signaling; Primary ovarian insufficiency; A network map of Macrophage-stimulating protein (MSP) signaling; ErbB signaling pathway; T-cell receptor signaling pathway; Serotonin HTR1 group and FOS pathway"	"Role of LAT2/NTAL/LAB on calcium mobilization; FCERI mediated NF-kB activation; Downstream TCR signaling; CLEC7A (Dectin-1) signaling; Constitutive Signaling by AKT1 E17K in Cancer; PIP3 activates AKT signaling; Regulation of TP53 Degradation; GPVI-mediated activation cascade; CD28 dependent PI3K/Akt signaling; G beta:gamma signalling through PI3Kgamma; RHO GTPases activate PKNs; Activation of AKT2; Integrin signaling; RSK activation; VEGFR2 mediated vascular permeability; VEGFR2 mediated cell proliferation; Estrogen-stimulated signaling through PRKCZ; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways"	"46"	"0"	"18.2"	"14.8"	"27.6"	"30.0"	"37.3"	"66.7"	"101.6"	"222.8"	"318.7"	"465.3"	"656.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86TV6"	"Tetratricopeptide repeat protein 7B OS=Homo sapiens OX=9606 GN=TTC7B PE=1 SV=3"	"5"	"3"	"6"	"3"	"843"	"94.1"	"6.89"	"794.18"	"15.21"	"2"	"3"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol"	""	"Pf12895, Pf13181, Pf13424, Pf19440"	"145567"	"ENSG00000165914"	"TTC7B"	"hsa:145567; Q86TV6; Q86U24; Q86VT3"	""	""	"0"	"0"	"51.9"	"64.6"	"65.0"	"53.1"	"68.3"	"53.7"	"83.8"	"139.7"	"390.0"	"614.9"	"810.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01484"	"Ankyrin-2 OS=Homo sapiens OX=9606 GN=ANK2 PE=1 SV=4"	"1"	"5"	"10"	"1"	"3957"	"433.4"	"5.14"	"1672.52"	"15.21"	"5"	"5"	"cell-cell signaling;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00023, Pf00531, Pf00791, Pf12796, Pf17809"	"287"	"ENSG00000145362"	"ANK2"	"hsa:287; Q01484; Q01485; Q08AC7; Q08AC8; Q7Z3L5"	""	"COPI-mediated anterograde transport; Interaction between L1 and Ankyrins"	"2"	"1"	"56.9"	"57.3"	"64.0"	"60.6"	"58.4"	"65.2"	"69.1"	"85.7"	"230.1"	"481.8"	"627.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15287"	"RNA-binding protein with serine-rich domain 1 OS=Homo sapiens OX=9606 GN=RNPS1 PE=1 SV=1"	"11"	"3"	"9"	"3"	"305"	"34.2"	"11.84"	"1705.08"	"15.18"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"10921"	"ENSG00000205937"	"RNPS1"	"A8K1P0; B4DDU8; B4DZU7; B7ZA17; hsa:10921; O75308; Q15287; Q32P25; Q8WY42; Q9NYG3"	"mRNA processing"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA Splicing - Major Pathway; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"7"	"0"	"450.5"	"488.1"	"468.4"	"396.0"	"450.0"	"474.9"	"558.2"	"651.4"	"998.7"	"2163.8"	"2940.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IY18"	"Structural maintenance of chromosomes protein 5 OS=Homo sapiens OX=9606 GN=SMC5 PE=1 SV=2"	"5"	"5"	"10"	"5"	"1101"	"128.7"	"8.38"	"1415.57"	"15.13"	"4"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02463"	"23137"	"ENSG00000198887"	"SMC5"	"A6NM81; hsa:23137; O60335; Q05D92; Q5VZ60; Q8IY18; Q96SB9"	""	"SUMOylation of DNA damage response and repair proteins"	"1"	"0"	"65.8"	"51.1"	"69.7"	"56.7"	"59.8"	"63.9"	"93.9"	"183.5"	"498.1"	"828.1"	"1330.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BRP1"	"Programmed cell death protein 2-like OS=Homo sapiens OX=9606 GN=PDCD2L PE=1 SV=1"	"14"	"3"	"5"	"3"	"358"	"39.4"	"4.86"	"256.99"	"15.12"	"1"	"3"	"cell cycle OR cell proliferation;other biological processes"	"other cell component"	""	"Pf04194"	"84306"	"ENSG00000126249"	"PDCD2L"	"hsa:84306; Q9BRP1"	""	""	"0"	"0"	"168.2"	"127.6"	"144.8"	"148.9"	"170.3"	"153.7"	"200.6"	"288.1"	"458.3"	"684.0"	"786.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14561"	"Acyl carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFAB1 PE=1 SV=3"	"19"	"4"	"7"	"4"	"156"	"17.4"	"4.93"	"1208.97"	"15.12"	"3"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"other membranes;cytosol;mitochondrion;nucleus"	"translation activity;other molecular function"	"Pf00550"	"4706"	"ENSG00000004779"	"NDUFAB1"	"B2R4M1; hsa:4706; O14561; Q9UNV1"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Glyoxylate metabolism and glycine degradation; Mitochondrial Fatty Acid Beta-Oxidation; Complex I biogenesis"	"7"	"0"	"199.1"	"217.7"	"196.5"	"176.2"	"221.3"	"219.0"	"298.8"	"460.1"	"1210.2"	"2237.2"	"3338.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95785"	"Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2"	"2"	"3"	"6"	"3"	"1651"	"178.6"	"6.86"	"1525.11"	"15.12"	"3"	"3"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	""	"58525"	"ENSG00000011451"	"WIZ"	"B3KVH1; B7ZM82; hsa:58525; M0QY21; O95785; Q4G0E0; Q6P6B0; Q6ZN24; Q7LDY6; Q7LDZ1; Q96IG5; Q96SQ6; Q9BUR8; Q9NPT1"	""	""	"0"	"0"	"125.9"	"148.4"	"166.4"	"139.8"	"148.1"	"152.5"	"184.0"	"186.1"	"231.1"	"302.6"	"390.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15691"	"Microtubule-associated protein RP/EB family member 1 OS=Homo sapiens OX=9606 GN=MAPRE1 PE=1 SV=3"	"22"	"4"	"7"	"4"	"268"	"30.0"	"5.14"	"1724.70"	"15.12"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf03271"	"22919"	"ENSG00000101367"	"MAPRE1"	"B2R6I7; E1P5M8; hsa:22919; Q15691; Q3KQS8"	"Microtubule cytoskeleton regulation"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; Anchoring of the basal body to the plasma membrane; The role of GTSE1 in G2/M progression after G2 checkpoint; Recruitment of NuMA to mitotic centrosomes; EML4 and NUDC in mitotic spindle formation; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; AURKA Activation by TPX2; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"15"	"0"	"170.8"	"173.8"	"204.9"	"201.2"	"202.4"	"195.3"	"264.5"	"278.4"	"431.9"	"1214.6"	"5861.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13619"	"Cullin-4A OS=Homo sapiens OX=9606 GN=CUL4A PE=1 SV=3"	"6"	"5"	"9"	"1"	"759"	"87.6"	"8.13"	"1341.42"	"15.10"	"4"	"5"	"cell cycle OR cell proliferation;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00888, Pf10557"	"8451"	"ENSG00000139842"	"CUL4A"	"A2A2W2; hsa:8451; O75834; Q13619; Q589T6; Q5TC62; Q6UP08; Q9UP17"	"Hippo-Merlin signaling dysregulation; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"Neddylation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; DNA Damage Recognition in GG-NER; Dual Incision in GG-NER"	"13"	"0"	"71.3"	"74.2"	"66.9"	"62.7"	"74.0"	"69.1"	"68.3"	"85.5"	"301.8"	"620.8"	"944.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12769"	"Nuclear pore complex protein Nup160 OS=Homo sapiens OX=9606 GN=NUP160 PE=1 SV=3"	"3"	"4"	"9"	"4"	"1436"	"162.0"	"5.50"	"1663.98"	"15.09"	"3"	"4"	"other metabolic processes;transport;developmental processes"	"cytosol;nucleus"	"other molecular function"	"Pf11715"	"23279"	"ENSG00000030066"	"NUP160"	"B4DYE8; B4E2J9; hsa:23279; Q08AD3; Q12769; Q7Z5X6; Q96GB3; Q9H660"	""	"Rev-mediated nuclear export of HIV RNA; Nuclear import of Rev protein; Postmitotic nuclear pore complex (NPC) reformation; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; HCMV Late Events; HCMV Early Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"35"	"0"	"472.4"	"441.4"	"587.7"	"474.5"	"494.3"	"500.7"	"647.3"	"823.0"	"1251.7"	"1878.6"	"2540.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y230"	"RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3"	"11"	"5"	"9"	"5"	"463"	"51.1"	"5.64"	"1382.51"	"15.03"	"4"	"5"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06068, Pf17856"	"10856"	"ENSG00000183207"	"RUVBL2"	"B3KQ59; E7ETE5; hsa:10856; Q6FIB9; Q6PK27; Q9Y230; Q9Y361"	""	"HATs acetylate histones; Telomere Extension By Telomerase"	"2"	"0"	"303.1"	"354.6"	"324.2"	"297.9"	"370.8"	"339.4"	"401.3"	"490.3"	"830.6"	"1617.0"	"2395.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14697"	"Neutral alpha-glucosidase AB OS=Homo sapiens OX=9606 GN=GANAB PE=1 SV=3"	"7"	"4"	"6"	"4"	"944"	"106.8"	"6.14"	"1142.93"	"15.01"	"2"	"4"	"protein metabolism;other metabolic processes"	"ER/Golgi;other cell component"	"other molecular function"	"Pf01055, Pf13802"	"23193"	"ENSG00000089597"	"GANAB"	"A6NC20; hsa:23193; Q14697; Q8WTS9; Q9P0X0"	"N-glycan biosynthesis"	"Maturation of spike protein; Calnexin/calreticulin cycle; Maturation of spike protein"	"5"	"0"	"237.7"	"197.0"	"244.5"	"226.4"	"234.4"	"280.5"	"294.0"	"299.4"	"291.0"	"295.2"	"360.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P0K7"	"Ankycorbin OS=Homo sapiens OX=9606 GN=RAI14 PE=1 SV=2"	"3"	"3"	"8"	"2"	"980"	"110.0"	"6.21"	"1649.17"	"14.98"	"3"	"3"	"other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf00023, Pf12796"	"26064"	"ENSG00000039560"	"RAI14"	"E9PED3; hsa:26064; Q6V1W9; Q7Z5I4; Q7Z733; Q9P0K7; Q9P2L2; Q9Y3T5"	""	""	"0"	"0"	"101.2"	"86.2"	"117.5"	"111.2"	"119.2"	"120.5"	"136.1"	"172.5"	"299.6"	"491.2"	"623.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99569"	"Plakophilin-4 OS=Homo sapiens OX=9606 GN=PKP4 PE=1 SV=2"	"5"	"4"	"8"	"4"	"1192"	"131.8"	"8.94"	"1433.82"	"14.90"	"4"	"4"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00514"	"8502"	"ENSG00000144283"	"PKP4"	"hsa:8502; Q86W91; Q99569"	""	"Formation of the cornified envelope; RND2 GTPase cycle; RND3 GTPase cycle; RND1 GTPase cycle"	"5"	"0"	"60.1"	"61.7"	"80.4"	"71.9"	"75.4"	"65.2"	"86.4"	"89.7"	"190.0"	"392.1"	"619.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P80303"	"Nucleobindin-2 OS=Homo sapiens OX=9606 GN=NUCB2 PE=1 SV=3"	"14"	"5"	"9"	"5"	"420"	"50.2"	"5.12"	"1872.62"	"14.87"	"5"	"4"	"signal transduction"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf13499"	"4925"	"ENSG00000070081"	"NUCB2"	"A8K642; D3DQX5; hsa:4925; P80303; Q8NFT5; V9HW75"	""	""	"0"	"0"	"359.7"	"363.8"	"432.7"	"347.8"	"403.9"	"449.3"	"492.8"	"544.5"	"638.5"	"765.2"	"974.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62424"	"60S ribosomal protein L7a OS=Homo sapiens OX=9606 GN=RPL7A PE=1 SV=2"	"18"	"7"	"12"	"7"	"266"	"30.0"	"10.61"	"2569.11"	"14.83"	"7"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01248"	"6130"	"ENSG00000148303; ENSG00000280858"	"RPL7A"	"hsa:6130; P11518; P62424; Q5T8U4"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; SRP-dependent cotranslational protein targeting to membrane; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"724.0"	"642.6"	"723.6"	"623.7"	"701.8"	"716.6"	"860.9"	"1015.3"	"1533.3"	"2773.6"	"4717.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95202"	"Mitochondrial proton/calcium exchanger protein OS=Homo sapiens OX=9606 GN=LETM1 PE=1 SV=1"	"6"	"4"	"8"	"4"	"739"	"83.3"	"6.70"	"1460.10"	"14.82"	"4"	"4"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;translation activity;other molecular function"	"Pf07766"	"3954"	"ENSG00000168924"	"LETM1"	"B4DED2; hsa:3954; O95202; Q9UF65"	"4p16.3 copy number variation"	"RHOG GTPase cycle; Mitochondrial calcium ion transport"	"3"	"0"	"176.5"	"146.2"	"193.2"	"159.0"	"197.9"	"183.9"	"233.5"	"267.7"	"543.0"	"1296.1"	"1818.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q4G0J3"	"La-related protein 7 OS=Homo sapiens OX=9606 GN=LARP7 PE=1 SV=1"	"8"	"5"	"9"	"5"	"582"	"66.9"	"9.55"	"1714.52"	"14.82"	"4"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf05383, Pf08777"	"51574"	"ENSG00000174720"	"LARP7"	"B2ZHN6; hsa:51574; Q3B7A9; Q4G0J3; Q9P1S7; Q9Y3Z8"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"187.7"	"117.0"	"202.3"	"185.0"	"184.4"	"185.6"	"216.7"	"241.2"	"327.3"	"463.4"	"647.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94763"	"Unconventional prefoldin RPB5 interactor 1 OS=Homo sapiens OX=9606 GN=URI1 PE=1 SV=3"	"13"	"5"	"8"	"4"	"535"	"59.8"	"5.05"	"1320.89"	"14.82"	"4"	"4"	"other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02996"	"8725"	"ENSG00000105176"	"URI1"	"A8K805; H7BY42; hsa:8725; O94763; Q8TC23; Q9UNU3"	""	""	"0"	"0"	"54.9"	"45.6"	"48.4"	"52.7"	"54.8"	"43.7"	"68.0"	"78.7"	"196.7"	"456.4"	"671.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13098"	"COP9 signalosome complex subunit 1 OS=Homo sapiens OX=9606 GN=GPS1 PE=1 SV=4"	"13"	"5"	"8"	"5"	"491"	"55.5"	"6.74"	"1551.81"	"14.81"	"4"	"4"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf01399, Pf10602"	"2873"	"ENSG00000169727"	"GPS1"	"hsa:2873; Q13098; Q8NA10; Q9BWL1"	""	"Neddylation; Cargo recognition for clathrin-mediated endocytosis; Formation of TC-NER Pre-Incision Complex; RHOBTB1 GTPase cycle; DNA Damage Recognition in GG-NER"	"5"	"0"	"125.1"	"114.6"	"133.4"	"109.9"	"145.5"	"138.0"	"181.7"	"261.4"	"570.5"	"1404.9"	"2254.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UN86"	"Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2"	"11"	"4"	"7"	"4"	"482"	"54.1"	"5.55"	"1164.22"	"14.80"	"3"	"4"	"cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf02136"	"9908"	"ENSG00000138757"	"G3BP2"	"A8K6X1; hsa:9908; O60606; O75149; Q9UN86; Q9UPA1"	""	"SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"1"	"0"	"553.4"	"438.2"	"549.3"	"527.8"	"559.8"	"610.5"	"642.4"	"708.9"	"949.4"	"1567.2"	"2643.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H078"	"Caseinolytic peptidase B protein homolog OS=Homo sapiens OX=9606 GN=CLPB PE=1 SV=1"	"7"	"4"	"7"	"4"	"707"	"78.7"	"9.01"	"1194.69"	"14.78"	"3"	"4"	"stress response;signal transduction;other biological processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf07724, Pf10431, Pf12796, Pf13857"	"81570"	"ENSG00000162129"	"CLPB"	"B4DXJ7; B4DXP7; B4DXW4; E7EWN6; F8W7P6; hsa:81570; Q8ND11; Q9H078; Q9H8Y0"	""	""	"0"	"0"	"146.5"	"128.9"	"159.9"	"128.4"	"158.1"	"147.4"	"182.8"	"240.1"	"520.6"	"1484.2"	"2543.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NPJ3"	"Acyl-coenzyme A thioesterase 13 OS=Homo sapiens OX=9606 GN=ACOT13 PE=1 SV=1"	"18"	"2"	"8"	"2"	"140"	"15.0"	"9.14"	"1563.25"	"14.77"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;mitochondrion"	"other molecular function"	"Pf03061"	"55856"	"ENSG00000112304"	"ACOT13"	"F5H2L4; hsa:55856; O95549; Q9NPJ3"	""	"Mitochondrial Fatty Acid Beta-Oxidation"	"1"	"0"	"73.9"	"54.9"	"83.7"	"71.6"	"95.4"	"92.8"	"90.6"	"147.9"	"291.8"	"538.3"	"849.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P48059"	"LIM and senescent cell antigen-like-containing domain protein 1 OS=Homo sapiens OX=9606 GN=LIMS1 PE=1 SV=4"	"16"	"5"	"8"	"5"	"325"	"37.2"	"8.05"	"1149.39"	"14.75"	"3"	"5"	"cell adhesion;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00412"	"3987"	"ENSG00000169756"	"LIMS1"	"B2RAJ4; B7Z483; B7Z7R3; B7Z907; hsa:3987; P48059; Q53TE0; Q9BS44"	"Primary focal segmental glomerulosclerosis (FSGS)"	"Regulation of cytoskeletal remodeling and cell spreading by IPP complex components"	"3"	"0"	"238.6"	"214.4"	"274.2"	"240.5"	"297.2"	"205.7"	"312.5"	"481.2"	"1647.2"	"2333.2"	"2728.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3B4"	"Splicing factor 3B subunit 6 OS=Homo sapiens OX=9606 GN=SF3B6 PE=1 SV=1"	"30"	"3"	"7"	"3"	"125"	"14.6"	"9.38"	"931.65"	"14.74"	"2"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076"	"51639"	"ENSG00000115128"	"SF3B6"	"hsa:51639; Q53TM1; Q9Y3B4"	""	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"2"	"0"	"86.5"	"116.8"	"108.9"	"80.9"	"90.5"	"77.3"	"127.2"	"217.8"	"438.8"	"901.7"	"1517.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N9N8"	"Probable RNA-binding protein EIF1AD OS=Homo sapiens OX=9606 GN=EIF1AD PE=1 SV=1"	"20"	"3"	"8"	"3"	"165"	"19.0"	"5.21"	"1559.35"	"14.68"	"3"	"3"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01176"	"84285"	"ENSG00000175376"	"EIF1AD"	"B2R4N5; hsa:84285; Q8N9N8; Q9BSC1"	""	""	"0"	"0"	"194.7"	"183.8"	"488.3"	"231.9"	"378.6"	"240.1"	"302.1"	"302.1"	"592.1"	"1236.3"	"1848.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5B9"	"FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1"	"6"	"6"	"9"	"6"	"1047"	"119.8"	"5.66"	"1440.60"	"14.68"	"4"	"5"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus"	"other molecular function"	"Pf00557, Pf08512, Pf08644, Pf14826"	"11198"	"ENSG00000092201"	"SUPT16H"	"hsa:11198; Q6GMT8; Q6P2F1; Q6PJM1; Q9NRX0; Q9Y5B9"	""	"Regulation of TP53 Activity through Phosphorylation; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes"	"12"	"0"	"301.0"	"272.6"	"334.3"	"300.2"	"366.9"	"354.8"	"398.7"	"583.8"	"1246.7"	"3015.3"	"5269.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BVP2"	"Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2"	"13"	"5"	"8"	"5"	"549"	"62.0"	"9.16"	"1438.75"	"14.59"	"4"	"4"	"cell cycle OR cell proliferation;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01926, Pf08701"	"26354"	"ENSG00000163938"	"GNL3"	"B2RDC1; hsa:26354; Q5PU80; Q96SV6; Q96SV7; Q9BVP2; Q9UJY0"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"71.6"	"83.1"	"97.1"	"82.6"	"94.8"	"92.1"	"108.4"	"159.8"	"332.7"	"733.2"	"1057.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P17980"	"26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3 PE=1 SV=3"	"11"	"3"	"6"	"3"	"439"	"49.2"	"5.24"	"1529.35"	"14.54"	"3"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf16450, Pf17862"	"5702"	"ENSG00000165916"	"PSMC3"	"B2R8V1; hsa:5702; P17980; Q3B757; Q3B865; Q53HU5; Q6GPG8; Q6IBS1; Q96HD3"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Neutrophil degranulation; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Regulation of expression of SLITs and ROBOs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"64"	"0"	"140.0"	"126.1"	"161.7"	"155.4"	"163.5"	"157.6"	"169.3"	"199.2"	"278.8"	"483.8"	"1016.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P83916"	"Chromobox protein homolog 1 OS=Homo sapiens OX=9606 GN=CBX1 PE=1 SV=1"	"13"	"2"	"8"	"1"	"185"	"21.4"	"4.93"	"1395.91"	"14.53"	"2"	"2"	"cell organization and biogenesis;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00385, Pf01393"	"10951"	"ENSG00000108468"	"CBX1"	"hsa:10951; P23197; P83916"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"HCMV Early Events"	"2"	"0"	"81.5"	"83.3"	"82.9"	"78.7"	"71.6"	"90.2"	"108.1"	"115.1"	"167.0"	"237.7"	"419.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WXA9"	"Splicing regulatory glutamine/lysine-rich protein 1 OS=Homo sapiens OX=9606 GN=SREK1 PE=1 SV=1"	"9"	"3"	"5"	"3"	"508"	"59.3"	"10.39"	"583.37"	"14.44"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf00076"	"140890"	"ENSG00000153914"	"SREK1"	"A4FTW3; hsa:140890; Q2M1J0; Q86X37; Q8WXA9"	"mRNA processing"	""	"1"	"0"	"130.3"	"96.1"	"134.8"	"126.7"	"120.6"	"123.3"	"159.9"	"208.2"	"483.4"	"876.3"	"1374.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06744"	"Glucose-6-phosphate isomerase OS=Homo sapiens OX=9606 GN=GPI PE=1 SV=4"	"9"	"4"	"8"	"4"	"558"	"63.1"	"8.32"	"1472.56"	"14.43"	"4"	"4"	"other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00342"	"2821"	"ENSG00000105220"	"GPI"	"B4DG39; hsa:2821; P06744; Q9BRD3; Q9BSK5; Q9UHE6"	"Cori cycle; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Aerobic glycolysis; N-glycan biosynthesis; Disorders of fructose metabolism; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders; UDP-derived sugars synthesis in fibroblasts"	"TP53 Regulates Metabolic Genes; Glycolysis; Gluconeogenesis; Neutrophil degranulation"	"13"	"0"	"224.0"	"184.9"	"289.0"	"266.9"	"287.9"	"294.6"	"318.4"	"395.4"	"1242.8"	"3076.3"	"4813.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13492"	"Phosphatidylinositol-binding clathrin assembly protein OS=Homo sapiens OX=9606 GN=PICALM PE=1 SV=2"	"10"	"4"	"6"	"4"	"652"	"70.7"	"7.90"	"1346.92"	"14.42"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf07651"	"8301"	"ENSG00000073921"	"PICALM"	"B4DTM3; E9PN05; F8VPG7; hsa:8301; O60700; Q13492; Q4LE54; Q6GMQ6; Q86XZ9"	""	"Cargo recognition for clathrin-mediated endocytosis; Golgi Associated Vesicle Biogenesis; RND3 GTPase cycle"	"4"	"0"	"107.8"	"99.6"	"107.3"	"102.4"	"117.7"	"121.8"	"181.3"	"271.4"	"539.9"	"857.9"	"1095.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NNW5"	"WD repeat-containing protein 6 OS=Homo sapiens OX=9606 GN=WDR6 PE=1 SV=1"	"4"	"4"	"8"	"4"	"1121"	"121.6"	"6.87"	"1561.78"	"14.41"	"4"	"4"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf00400"	"11180"	"ENSG00000178252"	"WDR6"	"B4DHK2; hsa:11180; Q3MIT1; Q9NNW5; Q9UF63"	""	"RND2 GTPase cycle; RHOV GTPase cycle; RHOU GTPase cycle; RND3 GTPase cycle; RND1 GTPase cycle"	"5"	"0"	"198.2"	"207.7"	"225.9"	"188.6"	"217.4"	"185.0"	"252.5"	"321.0"	"703.3"	"1687.6"	"2780.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UHD1"	"Cysteine and histidine-rich domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHORDC1 PE=1 SV=2"	"14"	"3"	"7"	"3"	"332"	"37.5"	"7.87"	"1013.89"	"14.39"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	""	"other molecular function"	"Pf04968, Pf04969"	"26973"	"ENSG00000110172; ENSG00000285023"	"CHORDC1"	"B2R6P8; hsa:26973; Q6IN49; Q8WVL9; Q9H3D6; Q9UHD1"	""	""	"0"	"0"	"120.7"	"130.1"	"134.9"	"120.7"	"123.4"	"109.3"	"150.7"	"178.5"	"404.5"	"1217.4"	"3529.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14314"	"Glucosidase 2 subunit beta OS=Homo sapiens OX=9606 GN=PRKCSH PE=1 SV=2"	"9"	"6"	"9"	"6"	"528"	"59.4"	"4.41"	"1842.25"	"14.37"	"5"	"4"	"protein metabolism;other metabolic processes;developmental processes;signal transduction"	"ER/Golgi;other cell component"	"other molecular function"	"Pf12999, Pf13015, Pf13202"	"5589"	"ENSG00000130175"	"PRKCSH"	"A8K318; hsa:5589; P14314; Q96BU9; Q96D06; Q9P0W9"	""	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Advanced glycosylation endproduct receptor signaling; Maturation of spike protein; Calnexin/calreticulin cycle; Maturation of spike protein"	"7"	"0"	"996.7"	"862.1"	"986.7"	"840.3"	"928.8"	"1016.0"	"1182.9"	"1193.2"	"1224.0"	"1310.0"	"1552.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14635"	"G2/mitotic-specific cyclin-B1 OS=Homo sapiens OX=9606 GN=CCNB1 PE=1 SV=1"	"7"	"3"	"8"	"3"	"433"	"48.3"	"7.47"	"1701.74"	"14.37"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00134, Pf02984"	"891"	"ENSG00000134057"	"CCNB1"	"A8K066; hsa:891; P14635; Q5TZP9"	"AMP-activated protein kinase signaling; miRNA regulation of DNA damage response; Cell cycle; Retinoblastoma gene in cancer; ATM signaling pathway; G1 to S cell cycle control; GDNF signaling; DNA damage response"	"The role of GTSE1 in G2/M progression after G2 checkpoint; Resolution of Sister Chromatid Cohesion; Nuclear Pore Complex (NPC) Disassembly; Regulation of PLK1 Activity at G2/M Transition; APC/C:Cdc20 mediated degradation of Cyclin B; Phosphorylation of the APC/C; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Cyclin A/B1/B2 associated events during G2/M transition; Transcriptional regulation by RUNX2; MASTL Facilitates Mitotic Progression; E2F-enabled inhibition of pre-replication complex formation; Golgi Cisternae Pericentriolar Stack Reorganization; Condensation of Prophase Chromosomes; Initiation of Nuclear Envelope (NE) Reformation; Polo-like kinase mediated events; Condensation of Prometaphase Chromosomes; Activation of NIMA Kinases NEK9, NEK6, NEK7; G2/M DNA replication checkpoint; Depolymerization of the Nuclear Lamina; Phosphorylation of Emi1"	"31"	"0"	"221.1"	"188.2"	"250.5"	"201.0"	"233.4"	"228.5"	"300.9"	"369.7"	"668.8"	"1335.4"	"1565.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13576"	"Ras GTPase-activating-like protein IQGAP2 OS=Homo sapiens OX=9606 GN=IQGAP2 PE=1 SV=4"	"4"	"7"	"12"	"4"	"1575"	"180.5"	"5.64"	"2008.38"	"14.36"	"7"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00307, Pf00612, Pf00616, Pf03836"	"10788"	"ENSG00000145703"	"IQGAP2"	"A8K4V1; B7Z8A4; hsa:10788; J3KR91; Q13576"	"Ciliary landscape; G13 signaling pathway"	"Neutrophil degranulation; RHO GTPases activate IQGAPs; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOG GTPase cycle"	"7"	"0"	"91.9"	"92.1"	"123.4"	"94.0"	"119.7"	"107.0"	"133.0"	"176.8"	"590.0"	"1425.0"	"1780.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7L5N1"	"COP9 signalosome complex subunit 6 OS=Homo sapiens OX=9606 GN=COPS6 PE=1 SV=1"	"15"	"4"	"5"	"4"	"327"	"36.1"	"5.73"	"896.26"	"14.33"	"2"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf01398, Pf13012"	"10980"	"ENSG00000168090"	"COPS6"	"A4D2A3; hsa:10980; O15387; Q7L5N1"	"Nucleotide-binding oligomerization domain (NOD) pathway; Ciliary landscape"	"Neddylation; Formation of TC-NER Pre-Incision Complex; DNA Damage Recognition in GG-NER; Cargo recognition for clathrin-mediated endocytosis"	"6"	"0"	"77.7"	"79.9"	"93.1"	"90.4"	"108.3"	"111.8"	"151.9"	"280.7"	"585.5"	"1897.5"	"4037.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14696"	"LRP chaperone MESD OS=Homo sapiens OX=9606 GN=MESD PE=1 SV=2"	"23"	"4"	"7"	"4"	"234"	"26.1"	"7.78"	"1450.22"	"14.33"	"3"	"4"	"cell-cell signaling;protein metabolism;other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi"	"signal transduction activity or receptor binding;other molecular function"	"Pf10185"	"23184"	"ENSG00000117899"	"MESD"	"B4DW84; D3DW96; hsa:23184; Q14696; Q969U1"	""	""	"0"	"0"	"81.8"	"66.7"	"82.5"	"78.9"	"77.6"	"106.2"	"148.9"	"258.6"	"1220.2"	"1634.4"	"2281.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UK45"	"U6 snRNA-associated Sm-like protein LSm7 OS=Homo sapiens OX=9606 GN=LSM7 PE=1 SV=1"	"56"	"3"	"5"	"3"	"103"	"11.6"	"5.27"	"285.40"	"14.31"	"1"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01423"	"51690"	"ENSG00000130332"	"LSM7"	"hsa:51690; Q9UK45"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA decay by 5' to 3' exoribonuclease"	"3"	"0"	"189.6"	"174.1"	"222.9"	"176.1"	"213.7"	"197.8"	"229.0"	"290.6"	"403.0"	"885.2"	"2101.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5T2N8"	"ATPase family AAA domain-containing protein 3C OS=Homo sapiens OX=9606 GN=ATAD3C PE=2 SV=2"	"12"	"3"	"5"	"1"	"411"	"46.4"	"9.31"	"827.61"	"14.27"	"2"	"3"	"cell organization and biogenesis"	"mitochondrion"	"other molecular function"	"Pf00004, Pf12037"	"219293"	"ENSG00000215915"	"ATAD3C"	"hsa:219293; Q5T2N8; Q8N1Z5"	"1p36 copy number variation syndrome"	""	"1"	"0"	"26.8"	"23.7"	"34.2"	"24.0"	"28.9"	"31.8"	"36.0"	"45.8"	"98.1"	"149.6"	"230.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P18124"	"60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1"	"12"	"2"	"8"	"2"	"248"	"29.2"	"10.65"	"1415.12"	"14.25"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00327, Pf08079"	"6129"	"ENSG00000147604"	"RPL7"	"A8K504; hsa:6129; P18124; Q15289; Q3KQU0; Q5I0X1; Q6IBM9"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"15"	"0"	"94.3"	"88.5"	"103.1"	"99.3"	"125.9"	"128.9"	"117.2"	"148.4"	"205.9"	"407.4"	"604.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UEE9"	"Craniofacial development protein 1 OS=Homo sapiens OX=9606 GN=CFDP1 PE=1 SV=1"	"15"	"4"	"6"	"4"	"299"	"33.6"	"4.81"	"962.36"	"14.23"	"2"	"4"	"cell adhesion;cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	""	"Pf07572"	"10428"	"ENSG00000153774"	"CFDP1"	"hsa:10428; O00393; O00404; Q9UEE9; Q9UEF0; Q9UEF1; Q9UEF8"	""	""	"0"	"0"	"375.8"	"337.4"	"402.7"	"375.1"	"373.9"	"398.2"	"456.2"	"477.0"	"698.4"	"1103.7"	"1534.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5H9R7"	"Serine/threonine-protein phosphatase 6 regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PPP6R3 PE=1 SV=2"	"7"	"5"	"7"	"5"	"873"	"97.6"	"4.60"	"1099.49"	"14.20"	"3"	"4"	"other biological processes"	"plasma membrane;other membranes;cytosol;nucleus"	"enzyme regulator activity;other molecular function"	"Pf04499"	"55291"	"ENSG00000110075"	"PPP6R3"	"hsa:55291; Q3B7I1; Q3I4Y0; Q3KR35; Q5H9R7; Q68CR3; Q7L4R8; Q8N3B2; Q96MB2; Q9H2K5; Q9H2K6; Q9HCL4; Q9NUY3"	""	"Telomere Extension By Telomerase; COPII-mediated vesicle transport"	"2"	"0"	"208.5"	"228.2"	"254.9"	"215.9"	"241.8"	"179.5"	"285.2"	"425.9"	"689.7"	"1180.3"	"1633.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51948"	"CDK-activating kinase assembly factor MAT1 OS=Homo sapiens OX=9606 GN=MNAT1 PE=1 SV=1"	"16"	"3"	"4"	"3"	"309"	"35.8"	"6.09"	"268.68"	"14.19"	"1"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus"	"enzyme regulator activity;other molecular function"	"Pf06391, Pf17121"	"4331"	"ENSG00000020426"	"MNAT1"	"G3V1U8; hsa:4331; P51948; Q15817; Q6ICQ7"	"Eukaryotic transcription initiation; G1 to S cell cycle control; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"RUNX1 regulates transcription of genes involved in differentiation of HSCs; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; Cyclin D associated events in G1; Cyclin A/B1/B2 associated events during G2/M transition; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; Formation of Incision Complex in GG-NER; Cyclin E associated events during G1/S transition ; Cyclin A:Cdk2-associated events at S phase entry"	"38"	"0"	"54.9"	"57.1"	"71.2"	"63.4"	"61.1"	"54.2"	"77.7"	"133.8"	"495.5"	"1017.8"	"1643.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60842"	"Eukaryotic initiation factor 4A-I OS=Homo sapiens OX=9606 GN=EIF4A1 PE=1 SV=1"	"9"	"3"	"8"	"3"	"406"	"46.1"	"5.48"	"2044.23"	"14.17"	"3"	"3"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"1973"	"ENSG00000161960"	"EIF4A1"	"B2R6L8; D3DTP9; hsa:1973; J3QLC4; P04765; P60842; Q5U018; Q61516"	"Translation factors; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Interferon type I signaling pathways"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Deadenylation of mRNA; ISG15 antiviral mechanism"	"11"	"0"	"108.1"	"134.3"	"130.4"	"107.1"	"111.3"	"121.5"	"144.9"	"206.7"	"292.3"	"461.0"	"711.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86UV5"	"Ubiquitin carboxyl-terminal hydrolase 48 OS=Homo sapiens OX=9606 GN=USP48 PE=1 SV=1"	"6"	"5"	"8"	"5"	"1035"	"119.0"	"6.05"	"1762.36"	"14.15"	"4"	"4"	"protein metabolism;other metabolic processes"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf00443"	"84196"	"ENSG00000090686"	"USP48"	"B7ZKS7; hsa:84196; Q2M3I4; Q5SZI4; Q5T3T5; Q6NX53; Q86UV5; Q8N3F6; Q96F64; Q96IQ3; Q9H5N3; Q9H5T7; Q9NUJ6; Q9NXR0"	""	"Ub-specific processing proteases"	"1"	"0"	"62.6"	"63.1"	"80.1"	"62.1"	"62.5"	"64.7"	"91.9"	"112.0"	"315.2"	"801.1"	"926.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P016"	"Thymocyte nuclear protein 1 OS=Homo sapiens OX=9606 GN=THYN1 PE=1 SV=1"	"26"	"5"	"10"	"5"	"225"	"25.7"	"9.25"	"1651.72"	"14.15"	"5"	"5"	""	""	""	"Pf01878"	"29087"	"ENSG00000151500"	"THYN1"	"hsa:29087; Q567Q2; Q9H3L4; Q9HC20; Q9P016"	""	""	"0"	"0"	"200.8"	"257.3"	"230.8"	"177.8"	"207.5"	"262.6"	"304.9"	"359.2"	"521.1"	"844.4"	"987.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14241"	"Elongin-A OS=Homo sapiens OX=9606 GN=ELOA PE=1 SV=2"	"10"	"7"	"11"	"7"	"798"	"89.9"	"9.57"	"2590.44"	"14.13"	"6"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf06881, Pf08711"	"6924"	"ENSG00000011007"	"ELOA"	"B2R7Q8; hsa:6924; Q14241; Q8IXH1"	"VEGFA-VEGFR2 signaling; 10q11.21q11.23 copy number variation syndrome"	"Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes"	"13"	"0"	"690.3"	"514.8"	"707.3"	"599.5"	"688.0"	"700.1"	"860.9"	"1229.8"	"2405.6"	"2802.3"	"3067.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86WJ1"	"Chromodomain-helicase-DNA-binding protein 1-like OS=Homo sapiens OX=9606 GN=CHD1L PE=1 SV=3"	"7"	"4"	"6"	"4"	"897"	"100.9"	"6.90"	"684.04"	"14.09"	"2"	"4"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00176, Pf00271"	"9557"	"ENSG00000131778"	"CHD1L"	"A5YM64; B4DDE1; B5MDZ7; hsa:9557; Q53EZ3; Q5VXX7; Q6DD94; Q6PK83; Q86WJ1; Q86XH3; Q96HF7; Q96SP3; Q9BVJ1; Q9NVV8"	"1q21.1 copy number variation syndrome; Nucleotide excision repair in xeroderma pigmentosum"	"Formation of Incision Complex in GG-NER; Dual Incision in GG-NER"	"4"	"0"	"174.9"	"174.4"	"188.7"	"180.3"	"189.0"	"183.4"	"221.3"	"252.9"	"470.7"	"1045.6"	"1390.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52907"	"F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3"	"19"	"3"	"5"	"3"	"286"	"32.9"	"5.69"	"827.92"	"14.08"	"2"	"3"	"cell organization and biogenesis"	"non-structural extracellular;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf01267"	"829"	"ENSG00000116489"	"CAPZA1"	"hsa:829; P52907; Q53FQ6; Q6FHD5"	""	"MHC class II antigen presentation; COPI-mediated anterograde transport; Sensory processing of sound by inner hair cells of the cochlea; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-independent Golgi-to-ER retrograde traffic; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Factors involved in megakaryocyte development and platelet production; Advanced glycosylation endproduct receptor signaling"	"8"	"0"	"51.3"	"42.5"	"53.5"	"53.1"	"65.7"	"45.9"	"59.3"	"100.8"	"201.7"	"381.4"	"600.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IXT5"	"RNA-binding protein 12B OS=Homo sapiens OX=9606 GN=RBM12B PE=1 SV=2"	"3"	"2"	"6"	"2"	"1001"	"118.0"	"6.81"	"619.09"	"14.01"	"1"	"2"	"other biological processes"	"nucleus;other cell component"	""	"Pf00076"	"389677"	"ENSG00000183808"	"RBM12B"	"A8MYB5; hsa:389677; Q8IXT5"	""	""	"0"	"0"	"119.5"	"116.6"	"138.4"	"114.0"	"143.6"	"134.0"	"155.4"	"170.9"	"354.5"	"758.4"	"1252.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H974"	"Queuine tRNA-ribosyltransferase accessory subunit 2 OS=Homo sapiens OX=9606 GN=QTRT2 PE=1 SV=1"	"13"	"3"	"4"	"3"	"415"	"46.7"	"6.81"	"483.12"	"13.93"	"1"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"other membranes;mitochondrion;other cell component"	"other molecular function"	"Pf01702"	"79691"	"ENSG00000151576"	"QTRT2"	"A6NGE9; B7Z472; B7Z5R2; hsa:79691; J3KR78; Q6IA59; Q9H974"	""	"tRNA modification in the nucleus and cytosol"	"1"	"0"	"65.2"	"59.9"	"70.8"	"58.1"	"64.5"	"72.6"	"80.9"	"129.9"	"280.3"	"654.6"	"978.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H0C8"	"Integrin-linked kinase-associated serine/threonine phosphatase 2C OS=Homo sapiens OX=9606 GN=ILKAP PE=1 SV=1"	"10"	"4"	"8"	"4"	"392"	"42.9"	"7.09"	"1501.96"	"13.91"	"4"	"4"	"protein metabolism;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf00481"	"80895"	"ENSG00000132323"	"ILKAP"	"B3KM39; hsa:80895; Q9H0C8"	"2q37 copy number variation syndrome"	""	"1"	"0"	"124.1"	"115.6"	"134.0"	"109.9"	"130.1"	"129.2"	"139.9"	"197.6"	"1190.9"	"2656.1"	"3603.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06753"	"Tropomyosin alpha-3 chain OS=Homo sapiens OX=9606 GN=TPM3 PE=1 SV=2"	"14"	"4"	"10"	"2"	"285"	"32.9"	"4.72"	"1622.41"	"13.91"	"4"	"4"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton"	"cytoskeletal activity"	"Pf00261"	"7170"	"ENSG00000143549"	"TPM3"	"D3DV71; hsa:7170; P06753; P12324; Q2QD06; Q5VU58; Q5VU63; Q5VU66; Q5VU71; Q5VU72; Q8TCG3; Q969Q2; Q9NQH8"	"Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4); Striated muscle contraction pathway; VEGFA-VEGFR2 signaling"	"Signaling by ALK fusions and activated point mutants; RHOV GTPase cycle; Smooth Muscle Contraction; Striated Muscle Contraction"	"7"	"0"	"160.6"	"165.4"	"182.2"	"175.6"	"176.8"	"159.4"	"206.0"	"296.0"	"509.5"	"781.3"	"901.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NBJ5"	"Procollagen galactosyltransferase 1 OS=Homo sapiens OX=9606 GN=COLGALT1 PE=1 SV=1"	"8"	"5"	"10"	"5"	"622"	"71.6"	"7.31"	"1546.51"	"13.91"	"5"	"5"	"cell organization and biogenesis;other biological processes"	"ER/Golgi"	"other molecular function"	"Pf01755, Pf13704"	"79709"	"ENSG00000130309"	"COLGALT1"	"hsa:79709; Q8NBJ5; Q8NC64"	"Type I collagen synthesis in the context of osteogenesis imperfecta"	"Collagen biosynthesis and modifying enzymes"	"2"	"0"	"260.1"	"242.2"	"257.9"	"234.4"	"268.2"	"245.4"	"315.2"	"439.0"	"1013.4"	"2457.7"	"3292.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EP5"	"DAZ-associated protein 1 OS=Homo sapiens OX=9606 GN=DAZAP1 PE=1 SV=1"	"15"	"4"	"9"	"4"	"407"	"43.4"	"8.56"	"2397.26"	"13.88"	"4"	"3"	"cell cycle OR cell proliferation;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"26528"	"ENSG00000071626"	"DAZAP1"	"hsa:26528; Q96EP5; Q96MJ3; Q9NRR9"	""	""	"0"	"0"	"388.9"	"317.9"	"422.3"	"374.6"	"399.6"	"311.6"	"445.2"	"518.7"	"620.4"	"784.5"	"1075.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19387"	"DNA-directed RNA polymerase II subunit RPB3 OS=Homo sapiens OX=9606 GN=POLR2C PE=1 SV=2"	"20"	"3"	"5"	"3"	"275"	"31.4"	"4.92"	"1184.64"	"13.84"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01000, Pf01193"	"5432"	"ENSG00000102978"	"POLR2C"	"hsa:5432; O15161; P19387"	"Pyrimidine metabolism; Eukaryotic transcription initiation; Primary ovarian insufficiency"	"Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; mRNA Splicing - Major Pathway; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"44"	"0"	"115.1"	"103.0"	"138.9"	"116.4"	"141.9"	"127.2"	"166.3"	"213.4"	"383.8"	"550.5"	"808.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99584"	"Protein S100-A13 OS=Homo sapiens OX=9606 GN=S100A13 PE=1 SV=1"	"21"	"2"	"4"	"2"	"98"	"11.5"	"6.16"	"511.82"	"13.82"	"1"	"2"	"transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01023"	"6284"	"ENSG00000189171"	"S100A13"	"hsa:6284; Q52PI9; Q6FGF8; Q99584"	""	""	"0"	"0"	"28.2"	"33.3"	"31.9"	"31.6"	"30.8"	"42.6"	"40.6"	"46.0"	"96.0"	"1830.8"	"4714.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BY42"	"Replication termination factor 2 OS=Homo sapiens OX=9606 GN=RTF2 PE=1 SV=3"	"22"	"6"	"10"	"6"	"306"	"33.9"	"8.59"	"2268.54"	"13.82"	"6"	"4"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf04641"	"51507"	"ENSG00000022277"	"RTF2"	"E1P5Z9; hsa:51507; Q9BY42; Q9BYL7; Q9HCV9; Q9NX29; Q9NZZ8; Q9P002; Q9UHW3"	""	""	"0"	"0"	"216.0"	"199.3"	"264.6"	"208.7"	"249.6"	"248.0"	"333.5"	"504.2"	"1307.6"	"1954.0"	"2704.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKL0"	"REST corepressor 1 OS=Homo sapiens OX=9606 GN=RCOR1 PE=1 SV=2"	"8"	"3"	"6"	"2"	"485"	"53.3"	"7.03"	"1517.54"	"13.78"	"3"	"3"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00249, Pf01448"	"23186"	"ENSG00000089902"	"RCOR1"	"hsa:23186; J3KN32; Q15044; Q6P2I9; Q86VG5; Q9UKL0"	""	"Regulation of PTEN gene transcription; Potential therapeutics for SARS; HDACs deacetylate histones; Factors involved in megakaryocyte development and platelet production"	"4"	"1"	"145.4"	"143.1"	"147.9"	"138.2"	"158.6"	"131.8"	"183.9"	"241.0"	"426.5"	"1180.5"	"2432.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5TBB1"	"Ribonuclease H2 subunit B OS=Homo sapiens OX=9606 GN=RNASEH2B PE=1 SV=1"	"18"	"5"	"7"	"5"	"312"	"35.1"	"9.13"	"1262.43"	"13.73"	"3"	"4"	"cell cycle OR cell proliferation;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	""	"Pf09468, Pf17745"	"79621"	"ENSG00000136104"	"RNASEH2B"	"G3XAJ1; hsa:79621; Q05DR2; Q5TBB1; Q6PK48; Q9HAF7"	""	""	"0"	"0"	"187.2"	"155.0"	"197.6"	"150.7"	"187.9"	"206.1"	"229.3"	"312.4"	"1717.8"	"3220.8"	"4323.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7L9B9"	"Endonuclease/exonuclease/phosphatase family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=EEPD1 PE=1 SV=2"	"8"	"3"	"4"	"3"	"569"	"62.4"	"8.41"	"277.39"	"13.71"	"1"	"3"	"DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes"	"nucleic acid binding activity"	"Pf12836"	"80820"	"ENSG00000122547"	"EEPD1"	"hsa:80820; Q7L9B9; Q96K64; Q9C0F7"	""	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"	"1"	"0"	"51.8"	"42.5"	"48.1"	"47.4"	"57.1"	"54.4"	"68.6"	"94.9"	"292.3"	"738.3"	"1117.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UHR5"	"SAP30-binding protein OS=Homo sapiens OX=9606 GN=SAP30BP PE=1 SV=1"	"17"	"5"	"9"	"5"	"308"	"33.9"	"4.84"	"1912.57"	"13.70"	"5"	"4"	"other biological processes"	"cytoskeleton;nucleus"	""	"Pf07818"	"29115"	"ENSG00000161526"	"SAP30BP"	"B3KML7; hsa:29115; Q8N1R5; Q8TDR8; Q96D27; Q9UHR5"	""	"NoRC negatively regulates rRNA expression"	"1"	"0"	"352.5"	"308.9"	"353.1"	"317.6"	"361.3"	"347.2"	"398.6"	"486.3"	"611.9"	"1211.8"	"1974.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IYB8"	"ATP-dependent RNA helicase SUPV3L1, mitochondrial OS=Homo sapiens OX=9606 GN=SUPV3L1 PE=1 SV=1"	"4"	"2"	"6"	"2"	"786"	"87.9"	"7.99"	"1448.98"	"13.68"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cytoplasmic organelle"	"nucleic acid binding activity;other molecular function"	"Pf00271, Pf12513, Pf18114, Pf18147"	"6832"	"ENSG00000156502"	"SUPV3L1"	"A8K301; hsa:6832; O43630; Q8IYB8"	""	""	"0"	"0"	"110.4"	"97.4"	"135.7"	"118.3"	"123.8"	"131.7"	"139.6"	"155.3"	"265.3"	"408.2"	"514.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UDY2"	"Tight junction protein ZO-2 OS=Homo sapiens OX=9606 GN=TJP2 PE=1 SV=2"	"4"	"4"	"8"	"4"	"1190"	"133.9"	"7.40"	"1438.73"	"13.67"	"4"	"4"	"cell adhesion;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00595, Pf00625, Pf07653"	"9414"	"ENSG00000119139"	"TJP2"	"A2A3H9; B7Z2R8; B7Z7T6; F5H301; F5H886; hsa:9414; Q15883; Q5VXL0; Q5VXL1; Q8N756; Q8NI14; Q99839; Q9UDY0; Q9UDY1; Q9UDY2"	"1q21.1 copy number variation syndrome; 15q11q13 copy number variation"	"RHOC GTPase cycle; RHOA GTPase cycle; RHOB GTPase cycle; Signaling by Hippo; Apoptotic cleavage of cell adhesion  proteins"	"7"	"0"	"133.8"	"111.5"	"147.9"	"128.4"	"133.2"	"147.7"	"172.3"	"225.6"	"511.6"	"1303.1"	"1591.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14745"	"Na(+)/H(+) exchange regulatory cofactor NHE-RF1 OS=Homo sapiens OX=9606 GN=SLC9A3R1 PE=1 SV=4"	"14"	"4"	"8"	"4"	"358"	"38.8"	"5.77"	"1254.53"	"13.66"	"4"	"4"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;transporter activity;cytoskeletal activity;other molecular function"	"Pf00595, Pf09007"	"9368"	"ENSG00000109062"	"NHERF1"	"B3KY21; hsa:9368; O14745; O43552; Q86WQ5"	"TAR syndrome"	""	"1"	"0"	"53.5"	"42.3"	"54.9"	"55.1"	"48.7"	"58.3"	"70.2"	"68.0"	"277.4"	"1062.1"	"1766.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16891"	"MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1"	"6"	"4"	"8"	"4"	"758"	"83.6"	"6.48"	"1393.41"	"13.66"	"4"	"4"	"cell organization and biogenesis;other biological processes"	"other membranes;mitochondrion"	""	"Pf09731"	"10989"	"ENSG00000132305"	"IMMT"	"B1H0U5; B2R5N6; hsa:10989; Q14539; Q15092; Q16891; Q68D41; Q69HW5; Q6IBL0; Q7Z3X1; Q8TAJ5; Q9P0V2"	""	"Cristae formation"	"1"	"0"	"169.1"	"144.4"	"184.1"	"172.3"	"175.3"	"175.4"	"203.7"	"263.9"	"525.7"	"1072.9"	"1697.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BTC0"	"Death-inducer obliterator 1 OS=Homo sapiens OX=9606 GN=DIDO1 PE=1 SV=5"	"2"	"3"	"6"	"3"	"2240"	"243.7"	"7.88"	"1497.70"	"13.64"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;signal transduction"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00628, Pf07500, Pf07744"	"11083"	"ENSG00000101191"	"DIDO1"	"A8MY65; B9EH82; E1P5I1; hsa:11083; O15043; Q3ZTL7; Q3ZTL8; Q4VXS1; Q4VXS2; Q4VXV8; Q4VXV9; Q96D72; Q9BQW0; Q9BTC0; Q9BW03; Q9H4G6; Q9H4G7; Q9NTU8; Q9NUM8; Q9UFB6"	""	""	"0"	"0"	"176.9"	"139.1"	"162.4"	"144.0"	"173.3"	"179.0"	"174.1"	"199.9"	"287.0"	"470.0"	"624.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P013"	"Spliceosome-associated protein CWC15 homolog OS=Homo sapiens OX=9606 GN=CWC15 PE=1 SV=2"	"14"	"2"	"4"	"2"	"229"	"26.6"	"5.71"	"281.38"	"13.62"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity"	"Pf04889"	"51503"	"ENSG00000150316"	"CWC15"	"B2RC17; hsa:51503; Q05BV9; Q05DM1; Q9P013; Q9UI29"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"116.6"	"112.1"	"111.7"	"94.2"	"119.7"	"100.1"	"134.4"	"152.2"	"247.4"	"706.5"	"1232.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NQG5"	"Regulation of nuclear pre-mRNA domain-containing protein 1B OS=Homo sapiens OX=9606 GN=RPRD1B PE=1 SV=1"	"15"	"5"	"8"	"3"	"326"	"36.9"	"5.97"	"1709.12"	"13.60"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf04818, Pf16566"	"58490"	"ENSG00000101413"	"RPRD1B"	"hsa:58490; Q1WDE7; Q6PKF4; Q9NQG5"	"Modulators of TCR signaling and T cell activation"	"RNA polymerase II transcribes snRNA genes"	"2"	"0"	"94.2"	"95.9"	"113.7"	"93.2"	"105.8"	"116.9"	"139.5"	"182.5"	"426.9"	"1147.4"	"1871.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63208"	"S-phase kinase-associated protein 1 OS=Homo sapiens OX=9606 GN=SKP1 PE=1 SV=2"	"21"	"3"	"6"	"3"	"163"	"18.6"	"4.54"	"1665.83"	"13.58"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf01466, Pf03931"	"6500"	"ENSG00000113558"	"SKP1"	"D3DQ97; D3DQ98; hsa:6500; P34991; P63208; Q8TAY2"	"Cell cycle; TNF-alpha signaling pathway; Breast cancer pathway; Small cell lung cancer; Notch signaling pathway"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; SCF-beta-TrCP mediated degradation of Emi1; Vpu mediated degradation of CD4; Degradation of beta-catenin by the destruction complex; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; NIK-->noncanonical NF-kB signaling; Orc1 removal from chromatin; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Neddylation; SCF(Skp2)-mediated degradation of p27/p21; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Regulation of PLK1 Activity at G2/M Transition; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Circadian Clock; Cyclin D associated events in G1; Regulation of BACH1 activity; MAP3K8 (TPL2)-dependent MAPK1/3 activation; NOTCH1 Intracellular Domain Regulates Transcription; Prolactin receptor signaling; Iron uptake and transport; Nuclear events stimulated by ALK signaling in cancer; Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling"	"38"	"0"	"90.2"	"79.0"	"123.4"	"105.3"	"121.8"	"107.9"	"151.4"	"187.6"	"505.5"	"961.5"	"1444.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12789"	"General transcription factor 3C polypeptide 1 OS=Homo sapiens OX=9606 GN=GTF3C1 PE=1 SV=4"	"4"	"5"	"8"	"5"	"2109"	"238.7"	"7.30"	"1457.87"	"13.57"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04182"	"2975"	"ENSG00000077235"	"GTF3C1"	"B2RP21; hsa:2975; Q12789; Q12838; Q6DKN9; Q9Y4W9"	""	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter"	"3"	"0"	"115.0"	"117.5"	"137.6"	"126.1"	"131.3"	"130.1"	"143.4"	"200.9"	"362.0"	"701.5"	"932.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13868"	"Exosome complex component RRP4 OS=Homo sapiens OX=9606 GN=EXOSC2 PE=1 SV=2"	"12"	"3"	"8"	"3"	"293"	"32.8"	"7.50"	"1608.25"	"13.56"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf14382, Pf15985"	"23404"	"ENSG00000130713"	"EXOSC2"	"A3KFL3; A3KFL4; B4DKK6; hsa:23404; Q13868; Q9NUY4"	"Ciliary landscape"	"ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Major pathway of rRNA processing in the nucleolus and cytosol; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	"7"	"0"	"144.0"	"144.9"	"147.7"	"148.1"	"151.4"	"154.3"	"191.4"	"252.6"	"408.6"	"1011.7"	"1937.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q3SY69"	"Mitochondrial 10-formyltetrahydrofolate dehydrogenase OS=Homo sapiens OX=9606 GN=ALDH1L2 PE=1 SV=2"	"6"	"3"	"4"	"3"	"923"	"101.7"	"6.52"	"371.79"	"13.54"	"1"	"3"	"other metabolic processes"	"mitochondrion;nucleus"	"other molecular function"	"Pf00171, Pf00550, Pf00551, Pf02911"	"160428"	"ENSG00000136010"	"ALDH1L2"	"hsa:160428; Q3SY68; Q3SY69; Q68D62; Q6AI55; Q8N922"	""	"Metabolism of folate and pterines"	"1"	"0"	"70.7"	"59.5"	"62.8"	"68.3"	"75.2"	"72.2"	"83.1"	"99.9"	"249.4"	"501.3"	"800.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19525"	"Interferon-induced, double-stranded RNA-activated protein kinase OS=Homo sapiens OX=9606 GN=EIF2AK2 PE=1 SV=2"	"7"	"3"	"8"	"3"	"551"	"62.1"	"8.40"	"1328.55"	"13.54"	"3"	"3"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;kinase activity;other molecular function"	"Pf00035, Pf00069"	"5610"	"ENSG00000055332"	"EIF2AK2"	"A8K3P0; D6W584; E9PC80; hsa:5610; P19525; Q52M43; Q7Z6F6; Q9UIR4"	"Translation factors; Alzheimer's disease and miRNA effects; Ebola virus infection in host; Measles virus infection; Type I interferon induction and signaling during SARS-CoV-2 infection; Host-pathogen interaction of human coronaviruses - interferon induction; Alzheimer's disease; Roles of ceramides in development of insulin resistance; Type II interferon signaling"	"ISG15 antiviral mechanism; Interferon alpha/beta signaling; Inhibition of PKR"	"12"	"0"	"77.9"	"89.6"	"90.3"	"70.0"	"81.4"	"73.2"	"115.4"	"162.3"	"410.3"	"910.0"	"1253.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P37108"	"Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2"	"41"	"8"	"15"	"8"	"136"	"14.6"	"10.04"	"3985.59"	"13.50"	"7"	"4"	"transport"	"non-structural extracellular;cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02290"	"6727"	"ENSG00000140319"	"SRP14"	"B5BUF5; hsa:6727; P37108; Q6B0K5; Q96Q14"	""	"Neutrophil degranulation; SRP-dependent cotranslational protein targeting to membrane"	"2"	"0"	"3109.6"	"2320.1"	"2880.8"	"2500.3"	"2674.2"	"2793.1"	"3524.7"	"3964.9"	"4372.4"	"3802.0"	"5728.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52434"	"DNA-directed RNA polymerases I, II, and III subunit RPABC3 OS=Homo sapiens OX=9606 GN=POLR2H PE=1 SV=4"	"26"	"3"	"6"	"3"	"150"	"17.1"	"4.68"	"1364.65"	"13.45"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf03870"	"5437"	"ENSG00000163882"	"POLR2H"	"C9J413; C9JBJ6; C9JCU7; C9JUA8; hsa:5437; P52434; P53802; Q969R0"	"Pyrimidine metabolism; Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"mRNA Splicing - Major Pathway; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; Estrogen-dependent gene expression; Formation of the Early Elongation Complex; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; B-WICH complex positively regulates rRNA expression; Abortive elongation of HIV-1 transcript in the absence of Tat; Activation of anterior HOX genes in hindbrain development during early embryogenesis; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; mRNA Splicing - Minor Pathway; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"57"	"0"	"189.2"	"174.2"	"187.0"	"192.9"	"216.0"	"230.2"	"219.9"	"282.2"	"579.2"	"1268.2"	"1950.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y520"	"Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4"	"2"	"5"	"9"	"5"	"2896"	"316.7"	"9.13"	"1905.39"	"13.43"	"5"	"4"	"cell organization and biogenesis;other biological processes"	"cytosol;other cell component"	""	"Pf07001"	"23215"	"ENSG00000117523"	"PRRC2C"	"hsa:23215; Q05DM8; Q49A39; Q6PD54; Q9H2N2; Q9HA05; Q9NSM8; Q9NXL3; Q9UF29; Q9UPQ6; Q9Y520"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"260.2"	"233.7"	"250.1"	"233.9"	"262.6"	"244.7"	"302.3"	"361.8"	"532.8"	"833.8"	"944.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95425"	"Supervillin OS=Homo sapiens OX=9606 GN=SVIL PE=1 SV=2"	"2"	"4"	"8"	"4"	"2214"	"247.6"	"6.98"	"1278.22"	"13.38"	"4"	"4"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00626, Pf02209"	"6840"	"ENSG00000197321"	"SVIL"	"D3DRW9; hsa:6840; M1J557; O60611; O60612; O95425; Q5VZK5; Q5VZK6; Q9H1R7"	""	""	"0"	"0"	"88.4"	"78.7"	"95.5"	"99.2"	"96.5"	"98.0"	"114.1"	"139.2"	"254.3"	"497.0"	"746.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96LB3"	"Intraflagellar transport protein 74 homolog OS=Homo sapiens OX=9606 GN=IFT74 PE=1 SV=1"	"8"	"3"	"6"	"3"	"600"	"69.2"	"6.00"	"1362.58"	"13.35"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	""	"80173"	"ENSG00000096872"	"IFT74"	"hsa:80173; Q3B789; Q5VY34; Q6PGQ8; Q96LB3; Q9H643; Q9H8G7"	"Ciliary landscape; Genes related to primary cilium development (based on CRISPR); Alstrom syndrome; Bardet-Biedl syndrome"	"Intraflagellar transport"	"5"	"0"	"71.8"	"70.5"	"74.6"	"65.5"	"70.0"	"76.8"	"84.0"	"109.1"	"170.0"	"405.0"	"644.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NRG9"	"Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1"	"9"	"4"	"8"	"4"	"546"	"59.5"	"7.50"	"1373.30"	"13.33"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus"	""	"Pf00400"	"8086"	"ENSG00000094914"	"AAAS"	"hsa:8086; Q5JB47; Q9NRG9; Q9NWI6; Q9UG19"	""	"ISG15 antiviral mechanism; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; SUMOylation of DNA damage response and repair proteins; Transport of Mature mRNA derived from an Intron-Containing Transcript; HCMV Early Events; HCMV Late Events; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; RHOA GTPase cycle"	"29"	"0"	"213.9"	"210.8"	"269.6"	"225.2"	"262.0"	"232.7"	"274.8"	"417.1"	"657.1"	"1755.4"	"1810.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52298"	"Nuclear cap-binding protein subunit 2 OS=Homo sapiens OX=9606 GN=NCBP2 PE=1 SV=1"	"31"	"3"	"5"	"3"	"156"	"18.0"	"8.21"	"616.87"	"13.32"	"2"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"22916"	"ENSG00000114503"	"NCBP2"	"B2RE91; B4DMK7; E9PAR5; hsa:22916; P52298; Q14924; Q2TS50"	"mRNA processing; 3q29 copy number variation syndrome"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Abortive elongation of HIV-1 transcript in the absence of Tat; RNA Polymerase II Pre-transcription Events; RNA polymerase II transcribes snRNA genes; mRNA Capping; mRNA Splicing - Major Pathway; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Signaling by FGFR2 IIIa TM; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; snRNP Assembly; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"29"	"0"	"198.2"	"185.8"	"196.6"	"159.1"	"181.3"	"212.2"	"243.7"	"313.5"	"445.6"	"781.7"	"1220.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EK6"	"Glucosamine 6-phosphate N-acetyltransferase OS=Homo sapiens OX=9606 GN=GNPNAT1 PE=1 SV=1"	"22"	"3"	"6"	"3"	"184"	"20.7"	"7.99"	"1217.11"	"13.31"	"3"	"3"	"other metabolic processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle"	"other molecular function"	"Pf00583"	"64841"	"ENSG00000100522"	"GNPNAT1"	"hsa:64841; Q96EK6"	""	"Synthesis of UDP-N-acetyl-glucosamine"	"1"	"0"	"162.1"	"135.6"	"198.0"	"164.7"	"174.7"	"168.7"	"207.2"	"204.0"	"261.7"	"535.3"	"1179.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NV88"	"Integrator complex subunit 9 OS=Homo sapiens OX=9606 GN=INTS9 PE=1 SV=2"	"7"	"3"	"5"	"3"	"658"	"73.8"	"6.33"	"637.70"	"13.28"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	""	"Pf16661"	"55756"	"ENSG00000104299"	"INTS9"	"B7Z560; B7Z6M5; hsa:55756; O00224; Q8TB16; Q9NV88"	"1p36 copy number variation syndrome"	"RNA polymerase II transcribes snRNA genes"	"2"	"0"	"95.1"	"104.9"	"99.2"	"96.6"	"95.8"	"99.6"	"121.2"	"147.9"	"366.9"	"640.6"	"885.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46109"	"Crk-like protein OS=Homo sapiens OX=9606 GN=CRKL PE=1 SV=1"	"17"	"4"	"8"	"4"	"303"	"33.8"	"6.74"	"1327.35"	"13.26"	"4"	"4"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00017, Pf00018, Pf07653"	"1399"	"ENSG00000099942"	"CRKL"	"A8KA44; D3DX35; hsa:1399; P46109"	"Androgen receptor network in prostate cancer; B cell receptor signaling pathway; IL-3 signaling pathway; Kit receptor signaling pathway; Focal adhesion; Hepatocyte growth factor receptor signaling; MAPK signaling pathway; Chemokine signaling pathway; EGF/EGFR signaling pathway; 22q11.2 copy number variation syndrome; IL-2 signaling pathway; A network map of Macrophage-stimulating protein (MSP) signaling; Interferon type I signaling pathways; ErbB signaling pathway; T-cell receptor signaling pathway"	"Regulation of signaling by CBL; Downstream signal transduction; Erythropoietin activates RAS; Frs2-mediated activation; MET activates RAP1 and RAC1; MET receptor recycling"	"21"	"0"	"321.8"	"262.0"	"312.7"	"288.4"	"291.6"	"284.6"	"355.2"	"417.2"	"463.5"	"546.3"	"809.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2E4"	"Disco-interacting protein 2 homolog C OS=Homo sapiens OX=9606 GN=DIP2C PE=1 SV=2"	"4"	"3"	"5"	"3"	"1556"	"170.7"	"7.39"	"560.99"	"13.26"	"2"	"3"	""	""	""	"Pf00501, Pf06464"	"22982"	"ENSG00000151240"	"DIP2C"	"B4DPI5; hsa:22982; Q5SS78; Q9Y2E4"	""	""	"0"	"0"	"62.3"	"69.5"	"75.7"	"67.1"	"60.7"	"63.7"	"88.9"	"124.1"	"227.6"	"499.1"	"679.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14008"	"Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3"	"2"	"4"	"6"	"4"	"2032"	"225.4"	"7.80"	"858.50"	"13.26"	"2"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02985, Pf12348"	"9793"	"ENSG00000175216"	"CKAP5"	"hsa:9793; Q05D70; Q0VAX7; Q0VAX8; Q14008; Q14668; Q2TA89; Q6NSH4"	"4p16.3 copy number variation"	"Separation of Sister Chromatids; Regulation of PLK1 Activity at G2/M Transition; Resolution of Sister Chromatid Cohesion; Recruitment of NuMA to mitotic centrosomes; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"14"	"0"	"148.1"	"117.8"	"144.1"	"110.7"	"128.3"	"154.4"	"152.8"	"209.2"	"502.2"	"862.4"	"1244.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35269"	"General transcription factor IIF subunit 1 OS=Homo sapiens OX=9606 GN=GTF2F1 PE=1 SV=2"	"10"	"4"	"6"	"4"	"517"	"58.2"	"7.49"	"1328.77"	"13.26"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf05793"	"2962"	"ENSG00000125651"	"GTF2F1"	"B2RCS0; hsa:2962; P35269; Q9BWN0"	""	"Viral Messenger RNA Synthesis; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; mRNA Splicing - Major Pathway; Estrogen-dependent gene expression; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM"	"32"	"0"	"222.4"	"152.1"	"214.8"	"192.3"	"214.4"	"245.3"	"291.8"	"315.3"	"446.2"	"824.0"	"1643.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBS4"	"DnaJ homolog subfamily B member 11 OS=Homo sapiens OX=9606 GN=DNAJB11 PE=1 SV=1"	"17"	"4"	"6"	"4"	"358"	"40.5"	"6.18"	"1477.46"	"13.24"	"3"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"non-structural extracellular;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00226, Pf01556"	"51726"	"ENSG00000090520"	"DNAJB11"	"hsa:51726; Q542Y5; Q542Y9; Q6IAQ8; Q96JC6; Q9UBS4"	"Photodynamic therapy-induced unfolded protein response"	"XBP1(S) activates chaperone genes"	"2"	"0"	"217.2"	"190.0"	"267.6"	"231.7"	"252.2"	"215.8"	"299.5"	"415.9"	"615.8"	"725.6"	"962.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H501"	"ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1"	"4"	"4"	"7"	"4"	"851"	"98.7"	"5.11"	"994.98"	"13.20"	"3"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf08159"	"51575"	"ENSG00000089048"	"ESF1"	"hsa:51575; Q86X92; Q9H501; Q9H9Q5; Q9HA35; Q9NX93; Q9P1S6"	""	""	"0"	"0"	"180.4"	"160.9"	"194.9"	"160.3"	"186.3"	"190.1"	"209.5"	"239.7"	"332.0"	"544.2"	"738.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13011"	"Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial OS=Homo sapiens OX=9606 GN=ECH1 PE=1 SV=2"	"14"	"5"	"6"	"5"	"328"	"35.8"	"8.00"	"1182.47"	"13.18"	"2"	"4"	"other metabolic processes"	"cytosol;mitochondrion;other cytoplasmic organelle"	"other molecular function"	"Pf00378"	"1891"	"ENSG00000104823; ENSG00000282853"	"ECH1"	"A8K745; hsa:1891; Q13011; Q8WVX0; Q96EZ9"	"Fatty acid biosynthesis; IL-18 signaling pathway"	"Peroxisomal protein import"	"3"	"0"	"254.5"	"186.8"	"257.0"	"243.6"	"298.2"	"296.7"	"317.2"	"399.5"	"925.8"	"2439.5"	"4524.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4E8"	"Ubiquitin carboxyl-terminal hydrolase 15 OS=Homo sapiens OX=9606 GN=USP15 PE=1 SV=3"	"5"	"4"	"7"	"4"	"981"	"112.3"	"5.22"	"948.18"	"13.17"	"3"	"4"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00443, Pf06337, Pf14533, Pf14836"	"9958"	"ENSG00000135655"	"USP15"	"hsa:9958; Q08AL5; Q9H8G9; Q9HCA6; Q9UNP0; Q9Y4E8; Q9Y5B5"	""	"Ub-specific processing proteases; UCH proteinases; Downregulation of TGF-beta receptor signaling"	"3"	"0"	"227.5"	"229.1"	"244.0"	"244.8"	"259.8"	"185.6"	"300.1"	"450.2"	"555.2"	"790.2"	"905.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BZF1"	"Oxysterol-binding protein-related protein 8 OS=Homo sapiens OX=9606 GN=OSBPL8 PE=1 SV=3"	"8"	"5"	"9"	"5"	"889"	"101.1"	"6.96"	"1853.19"	"13.16"	"5"	"4"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf00169, Pf01237"	"114882"	"ENSG00000091039"	"OSBPL8"	"A8K1T2; E9PE66; E9PE68; hsa:114882; Q52LQ3; Q68D75; Q8WXP8; Q9BZF1; Q9P277"	""	"Acyl chain remodelling of PS"	"1"	"0"	"207.8"	"175.9"	"227.5"	"206.0"	"219.7"	"222.4"	"248.2"	"295.0"	"591.5"	"996.3"	"1381.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z417"	"Nuclear fragile X mental retardation-interacting protein 2 OS=Homo sapiens OX=9606 GN=NUFIP2 PE=1 SV=1"	"8"	"4"	"6"	"4"	"695"	"76.1"	"8.70"	"926.96"	"13.14"	"3"	"2"	""	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity"	"Pf15293"	"57532"	"ENSG00000108256"	"NUFIP2"	"A1L3A6; A1L3A7; hsa:57532; Q7Z417; Q9P2M5"	""	""	"0"	"0"	"282.2"	"264.5"	"274.9"	"233.6"	"302.0"	"286.9"	"333.4"	"394.6"	"882.0"	"906.7"	"1060.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61218"	"DNA-directed RNA polymerases I, II, and III subunit RPABC2 OS=Homo sapiens OX=9606 GN=POLR2F PE=1 SV=1"	"32"	"3"	"5"	"3"	"127"	"14.5"	"4.22"	"499.10"	"13.11"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01192"	"5435"	"ENSG00000100142"	"POLR2F"	"hsa:5435; P41584; P61218; Q6IAY3"	"Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"mRNA Splicing - Major Pathway; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; B-WICH complex positively regulates rRNA expression; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"56"	"0"	"97.2"	"76.6"	"91.0"	"71.9"	"102.6"	"96.3"	"127.9"	"188.8"	"256.5"	"348.6"	"409.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19367"	"Hexokinase-1 OS=Homo sapiens OX=9606 GN=HK1 PE=1 SV=3"	"8"	"5"	"8"	"4"	"917"	"102.4"	"6.80"	"1755.06"	"13.05"	"4"	"4"	"other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;mitochondrion"	"kinase activity;other molecular function"	"Pf00349, Pf03727"	"3098"	"ENSG00000156515"	"HK1"	"E9PCK0; hsa:3098; O43443; O43444; O75574; P19367; Q5VTC3; Q96HC8; Q9NNZ4; Q9NNZ5"	"Cori cycle; Photodynamic therapy-induced HIF-1 survival signaling; Clear cell renal cell carcinoma pathways; Aerobic glycolysis; Disorders of fructose metabolism; Glucose metabolism in triple-negative breast cancer cells; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders; UDP-derived sugars synthesis in fibroblasts; Glucuronidation"	"Glycolysis; Defective HK1 causes hexokinase deficiency (HK deficiency)"	"12"	"1"	"134.9"	"137.5"	"147.4"	"137.1"	"131.5"	"144.9"	"171.7"	"224.8"	"605.6"	"1637.9"	"2505.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96J01"	"THO complex subunit 3 OS=Homo sapiens OX=9606 GN=THOC3 PE=1 SV=1"	"10"	"4"	"8"	"4"	"351"	"38.7"	"6.09"	"1398.82"	"13.05"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00400, Pf08662, Pf12894"	"84321"	"ENSG00000051596"	"THOC3"	"hsa:84321; Q6NZ53; Q96J01"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"3"	"0"	"416.6"	"336.3"	"472.5"	"394.1"	"462.1"	"419.6"	"560.2"	"657.5"	"1123.8"	"1887.7"	"3022.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94776"	"Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1"	"6"	"3"	"8"	"3"	"668"	"75.0"	"9.66"	"1294.80"	"13.02"	"3"	"3"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00320, Pf01426, Pf01448, Pf17226"	"9219"	"ENSG00000149480"	"MTA2"	"hsa:9219; O94776; Q68DB1; Q9UQB5"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"Potential therapeutics for SARS; Regulation of PTEN gene transcription; HDACs deacetylate histones; RNA Polymerase I Transcription Initiation; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of TP53 Activity through Acetylation"	"7"	"0"	"150.8"	"165.0"	"193.3"	"165.9"	"168.1"	"162.3"	"202.5"	"271.6"	"488.4"	"961.5"	"1503.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96GM8"	"Target of EGR1 protein 1 OS=Homo sapiens OX=9606 GN=TOE1 PE=1 SV=1"	"9"	"3"	"4"	"3"	"510"	"56.5"	"7.18"	"326.71"	"12.98"	"1"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00642, Pf04857"	"114034"	"ENSG00000132773"	"TOE1"	"B4DEM6; hsa:114034; Q6IA35; Q8IWN5; Q96GM8; Q9H846"	""	""	"0"	"0"	"80.7"	"65.0"	"82.5"	"68.3"	"84.7"	"67.2"	"96.5"	"108.8"	"266.0"	"576.7"	"705.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49321"	"Nuclear autoantigenic sperm protein OS=Homo sapiens OX=9606 GN=NASP PE=1 SV=2"	"5"	"4"	"8"	"4"	"788"	"85.2"	"4.30"	"1648.29"	"12.98"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf10516"	"4678"	"ENSG00000132780"	"NASP"	"A8K6H2; B4DQP3; D3DQ07; F5H3J2; hsa:4678; P49321; Q53GW5; Q5T622; Q5T625; Q96A69; Q9BTW2"	""	""	"0"	"0"	"649.8"	"684.8"	"674.7"	"607.3"	"677.4"	"716.2"	"844.2"	"984.5"	"1200.9"	"1462.6"	"1943.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60245"	"Protocadherin-7 OS=Homo sapiens OX=9606 GN=PCDH7 PE=1 SV=2"	"4"	"3"	"6"	"3"	"1069"	"116.0"	"5.19"	"1290.42"	"12.94"	"3"	"3"	"cell adhesion"	"plasma membrane;other membranes"	"other molecular function"	"Pf00028, Pf08266, Pf08374"	"5099"	"ENSG00000169851"	"PCDH7"	"hsa:5099; O60245; O60246; O60247; Q4W5C4"	""	"RHOA GTPase cycle; RHOB GTPase cycle; Platelet degranulation"	"3"	"0"	"50.5"	"48.7"	"61.1"	"58.3"	"55.9"	"61.6"	"82.4"	"99.6"	"310.8"	"1052.4"	"1822.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16555"	"Dihydropyrimidinase-related protein 2 OS=Homo sapiens OX=9606 GN=DPYSL2 PE=1 SV=1"	"5"	"2"	"5"	"2"	"572"	"62.3"	"6.38"	"874.57"	"12.92"	"1"	"2"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton"	"other molecular function"	"Pf01979"	"1808"	"ENSG00000092964"	"DPYSL2"	"A8K5H2; B4DR31; D3DSS7; hsa:1808; O00424; Q16555"	"Microtubule cytoskeleton regulation; Brain-derived neurotrophic factor (BDNF) signaling pathway"	"Recycling pathway of L1; CRMPs in Sema3A signaling"	"4"	"0"	"6.7"	"11.5"	"11.2"	"3.1"	"7.6"	"7.3"	"7.3"	"16.0"	"38.1"	"154.5"	"434.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49590"	"Histidine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=HARS2 PE=1 SV=1"	"10"	"5"	"10"	"1"	"506"	"56.9"	"8.24"	"1599.24"	"12.92"	"5"	"5"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf03129, Pf13393"	"23438"	"ENSG00000112855"	"HARS2"	"B4DDY8; hsa:23438; P49590"	"Primary ovarian insufficiency"	"Mitochondrial tRNA aminoacylation"	"2"	"0"	"8.8"	"6.6"	"11.5"	"9.8"	"12.9"	"4.7"	"10.0"	"15.3"	"32.0"	"59.6"	"80.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P41227"	"N-alpha-acetyltransferase 10 OS=Homo sapiens OX=9606 GN=NAA10 PE=1 SV=1"	"19"	"3"	"5"	"3"	"235"	"26.4"	"5.64"	"885.99"	"12.92"	"2"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00583"	"8260"	"ENSG00000102030"	"NAA10"	"A6NM98; hsa:8260; P41227"	""	""	"0"	"0"	"48.8"	"42.9"	"49.4"	"58.1"	"53.0"	"61.8"	"72.9"	"87.9"	"231.0"	"786.5"	"1168.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H993"	"Damage-control phosphatase ARMT1 OS=Homo sapiens OX=9606 GN=ARMT1 PE=1 SV=1"	"10"	"3"	"5"	"3"	"441"	"51.1"	"5.76"	"893.87"	"12.89"	"2"	"3"	"other metabolic processes;stress response"	""	"other molecular function"	"Pf01937"	"79624"	"ENSG00000146476"	"ARMT1"	"hsa:79624; Q96FC6; Q9H993; Q9UFY5"	""	""	"0"	"0"	"43.0"	"41.0"	"56.9"	"49.4"	"64.3"	"55.6"	"60.6"	"97.6"	"287.3"	"689.7"	"1054.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60645"	"Exocyst complex component 3 OS=Homo sapiens OX=9606 GN=EXOC3 PE=1 SV=3"	"7"	"3"	"6"	"3"	"745"	"85.5"	"6.29"	"1024.52"	"12.88"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf06046"	"11336"	"ENSG00000180104"	"EXOC3"	"hsa:11336; O60645; Q6P2E8; Q8TEN6; Q8WUW0; Q96DI4"	"Ciliary landscape"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"4"	"0"	"50.3"	"40.9"	"50.6"	"46.6"	"45.4"	"58.9"	"79.9"	"205.5"	"702.4"	"622.0"	"639.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y490"	"Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3"	"3"	"6"	"7"	"6"	"2541"	"269.6"	"6.07"	"1067.43"	"12.88"	"3"	"3"	"cell adhesion;cell organization and biogenesis;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00373, Pf01608, Pf08913, Pf09141, Pf16511"	"7094"	"ENSG00000137076"	"TLN1"	"A6NMY0; hsa:7094; Q86YD0; Q9NZQ2; Q9UHH8; Q9UPX3; Q9Y490"	"Integrin-mediated cell adhesion; Primary focal segmental glomerulosclerosis (FSGS); Focal adhesion; TROP2 regulatory signaling"	"Platelet degranulation ; Signaling by BRAF and RAF1 fusions; XBP1(S) activates chaperone genes; SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion; Smooth Muscle Contraction; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; GRB2:SOS provides linkage to MAPK signaling for Integrins ; p130Cas linkage to MAPK signaling for integrins"	"18"	"0"	"630.7"	"580.8"	"623.5"	"544.9"	"595.5"	"627.3"	"737.4"	"903.1"	"1967.8"	"2998.4"	"5010.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O96017"	"Serine/threonine-protein kinase Chk2 OS=Homo sapiens OX=9606 GN=CHEK2 PE=1 SV=1"	"9"	"3"	"5"	"3"	"543"	"60.9"	"5.91"	"1096.44"	"12.88"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"ER/Golgi;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00498"	"11200"	"ENSG00000183765"	"CHEK2"	"A8K3Y9; B7ZBF3; B7ZBF4; B7ZBF5; hsa:11200; O96017; Q6QA03; Q6QA04; Q6QA05; Q6QA06; Q6QA07; Q6QA08; Q6QA10; Q6QA11; Q6QA12; Q6QA13; Q9HBS5; Q9HCQ8; Q9UGF0; Q9UGF1"	"miRNA regulation of DNA damage response; Cell cycle; ATM signaling in development and disease ; miRNA regulation of p53 pathway in prostate cancer; DNA damage response"	"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Regulation of TP53 Degradation; Regulation of TP53 Activity through Phosphorylation; Regulation of TP53 Activity through Methylation; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; Stabilization of p53"	"13"	"0"	"18.5"	"12.0"	"23.8"	"22.3"	"24.9"	"23.3"	"31.4"	"36.4"	"107.9"	"379.8"	"690.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NU22"	"Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2"	"1"	"7"	"8"	"7"	"5596"	"632.4"	"5.68"	"1406.83"	"12.85"	"4"	"4"	"cell organization and biogenesis;transport"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf07728, Pf17865, Pf17867"	"23195"	"ENSG00000112159; ENSG00000288121"	"MDN1"	"hsa:23195; O15019; Q5T794; Q9NU22"	""	""	"0"	"0"	"291.2"	"246.0"	"284.9"	"237.7"	"277.2"	"300.0"	"343.5"	"461.0"	"1202.8"	"2582.4"	"3363.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16881"	"Thioredoxin reductase 1, cytoplasmic OS=Homo sapiens OX=9606 GN=TXNRD1 PE=1 SV=3"	"6"	"2"	"5"	"2"	"649"	"70.9"	"7.39"	"604.82"	"12.83"	"1"	"2"	"cell cycle OR cell proliferation;developmental processes;signal transduction;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00462, Pf02852, Pf07992"	"7296"	"ENSG00000198431"	"TXNRD1"	"B7Z1F4; B7Z3Y8; B7Z904; E9PMY9; F5H780; hsa:7296; Q16881; Q6FI31; Q6VB40; Q6VB41; Q6VB42; Q6VBP2; Q6VBP3; Q6VBP4; Q6VBP5; Q6VBP9; Q6VBQ0; Q6YNQ1; Q76P53; Q7LA96; Q8WVC8; Q99475; Q9UES8; Q9UH79"	"Selenium micronutrient network; Selenium micronutrient network ; Selenium micronutrient network; Nuclear receptors meta-pathway; NRF2 pathway; Oxidative stress response; Ferroptosis"	"PPARA activates gene expression; NFE2L2 regulating anti-oxidant/detoxification enzymes; Detoxification of Reactive Oxygen Species; TP53 Regulates Metabolic Genes; Interconversion of nucleotide di- and triphosphates; Metabolism of ingested H2SeO4 and H2SeO3 into H2Se; Uptake and function of diphtheria toxin; Metabolism of ingested MeSeO2H into MeSeH"	"15"	"0"	"20.9"	"17.0"	"17.5"	"19.2"	"18.3"	"20.3"	"25.4"	"36.7"	"100.7"	"234.2"	"365.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q06330"	"Recombining binding protein suppressor of hairless OS=Homo sapiens OX=9606 GN=RBPJ PE=1 SV=3"	"11"	"3"	"5"	"3"	"500"	"55.6"	"7.18"	"722.21"	"12.83"	"2"	"3"	"cell cycle OR cell proliferation;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09270, Pf09271, Pf20144"	"3516"	"ENSG00000168214"	"RBPJ"	"B4DY22; hsa:3516; Q06330; Q5XKH9; Q6P1N3"	"Neural crest differentiation; Notch signaling; Canonical and non-canonical Notch signaling; PTF1A related regulatory pathway; Epithelial to mesenchymal transition in colorectal cancer; Osteoblast differentiation and related diseases; Genetic causes of porto-sinusoidal vascular disease; Notch signaling pathway"	"Somitogenesis; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; NOTCH1 Intracellular Domain Regulates Transcription; Formation of paraxial mesoderm; Pre-NOTCH Transcription and Translation; Notch-HLH transcription pathway; NOTCH3 Intracellular Domain Regulates Transcription; Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells; NOTCH2 intracellular domain regulates transcription; NOTCH4 Intracellular Domain Regulates Transcription; RUNX3 regulates NOTCH signaling"	"20"	"0"	"87.5"	"67.3"	"98.1"	"79.1"	"87.6"	"95.5"	"106.5"	"179.6"	"1075.4"	"1237.5"	"1048.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q02218"	"2-oxoglutarate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=OGDH PE=1 SV=3"	"6"	"4"	"7"	"4"	"1023"	"115.9"	"6.86"	"1101.97"	"12.81"	"3"	"4"	"protein metabolism;other metabolic processes;developmental processes"	"other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00676, Pf02779, Pf16078, Pf16870"	"4967"	"ENSG00000105953"	"OGDH"	"B4E2U9; D3DVL0; E9PBM1; hsa:4967; Q02218; Q96DD3; Q9UDX0"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Thiamine metabolic pathways; 7q11.23 copy number variation syndrome; TCA cycle (aka Krebs or citric acid cycle)"	"Lysine catabolism; Glyoxylate metabolism and glycine degradation; Citric acid cycle (TCA cycle)"	"8"	"0"	"124.7"	"111.6"	"144.4"	"137.1"	"139.8"	"143.5"	"151.2"	"177.3"	"266.4"	"381.0"	"554.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N3U4"	"Cohesin subunit SA-2 OS=Homo sapiens OX=9606 GN=STAG2 PE=1 SV=3"	"3"	"4"	"6"	"2"	"1231"	"141.2"	"5.43"	"718.84"	"12.79"	"2"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf08514"	"10735"	"ENSG00000101972"	"STAG2"	"B1AMT5; D3DTF5; hsa:10735; O00540; Q5JTI6; Q68DE9; Q8N3U4; Q9H1N8"	"Cell cycle; Cohesin complex - Cornelia de Lange syndrome"	"Resolution of Sister Chromatid Cohesion; SUMOylation of DNA damage response and repair proteins; Separation of Sister Chromatids; Meiotic synapsis; Estrogen-dependent gene expression; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"9"	"1"	"81.9"	"66.0"	"90.4"	"70.9"	"83.1"	"83.3"	"104.2"	"130.6"	"354.5"	"1202.8"	"1771.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96ST3"	"Paired amphipathic helix protein Sin3a OS=Homo sapiens OX=9606 GN=SIN3A PE=1 SV=2"	"3"	"4"	"7"	"4"	"1273"	"145.1"	"7.25"	"1011.84"	"12.76"	"3"	"4"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02671, Pf08295, Pf16879"	"25942"	"ENSG00000169375"	"SIN3A"	"B2RNS5; hsa:25942; Q8N8N4; Q8NC83; Q8WV18; Q96L98; Q96ST3; Q9UFQ1"	"Androgen receptor signaling pathway; Retinoblastoma gene in cancer; MECP2 and associated Rett syndrome; Transcription co-factors SKI and SKIL protein partners; Hedgehog signaling pathway; 15q11q13 copy number variation"	"Cytoprotection by HMOX1; NoRC negatively regulates rRNA expression; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Factors involved in megakaryocyte development and platelet production; SUMOylation of transcription cofactors; FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes; MECP2 regulates transcription of neuronal ligands; Regulation of lipid metabolism by PPARalpha; Regulation of MECP2 expression and activity; STAT3 nuclear events downstream of ALK signaling; MECP2 regulates neuronal receptors and channels; Loss of MECP2 binding ability to 5mC-DNA"	"18"	"0"	"207.8"	"205.2"	"227.1"	"185.5"	"205.7"	"211.6"	"284.2"	"343.7"	"618.4"	"1570.4"	"3093.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00308"	"NEDD4-like E3 ubiquitin-protein ligase WWP2 OS=Homo sapiens OX=9606 GN=WWP2 PE=1 SV=2"	"3"	"2"	"6"	"2"	"870"	"98.9"	"7.12"	"1232.03"	"12.75"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00397, Pf00632"	"11060"	"ENSG00000198373"	"WWP2"	"A6NEP1; B2R706; B4DTL5; F5H213; H3BRF3; hsa:11060; I3RSG8; O00308; Q6ZTQ5; Q96CZ2; Q9BWN6"	""	"RHOQ GTPase cycle; Regulation of PTEN stability and activity; RHOJ GTPase cycle; NOTCH3 Activation and Transmission of Signal to the Nucleus; RHOU GTPase cycle"	"5"	"0"	"22.6"	"15.9"	"24.9"	"21.0"	"28.7"	"18.7"	"27.5"	"35.6"	"94.5"	"217.8"	"289.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00186"	"Syntaxin-binding protein 3 OS=Homo sapiens OX=9606 GN=STXBP3 PE=1 SV=2"	"8"	"4"	"8"	"4"	"592"	"67.7"	"7.80"	"1186.53"	"12.71"	"4"	"4"	"cell adhesion;cell-cell signaling;stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00995"	"6814"	"ENSG00000116266"	"STXBP3"	"A8K269; A8K5K7; hsa:6814; O00186; Q53FW1; Q86YJ3; Q9UPD7"	"Insulin signaling"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Disinhibition of SNARE formation"	"3"	"0"	"47.0"	"52.9"	"62.4"	"55.8"	"58.9"	"56.7"	"73.3"	"113.9"	"235.5"	"513.0"	"633.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5S2"	"Serine/threonine-protein kinase MRCK beta OS=Homo sapiens OX=9606 GN=CDC42BPB PE=1 SV=2"	"3"	"4"	"6"	"4"	"1711"	"194.2"	"6.37"	"1026.54"	"12.71"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00130, Pf00780, Pf08826, Pf15796"	"9578"	"ENSG00000198752"	"CDC42BPB"	"A9JR72; hsa:9578; Q2L7A5; Q86TJ1; Q9ULU5; Q9Y5S2"	"VEGFA-VEGFR2 signaling; 15q11q13 copy number variation"	"CDC42 GTPase cycle; RHOQ GTPase cycle; RHOJ GTPase cycle"	"5"	"0"	"38.6"	"47.7"	"54.0"	"44.7"	"57.8"	"51.2"	"75.0"	"135.5"	"296.4"	"354.9"	"404.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09972"	"Fructose-bisphosphate aldolase C OS=Homo sapiens OX=9606 GN=ALDOC PE=1 SV=2"	"15"	"6"	"9"	"2"	"364"	"39.4"	"6.87"	"1520.72"	"12.71"	"5"	"4"	"other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00274"	"230"	"ENSG00000109107"	"ALDOC"	"B2R5R3; hsa:230; P09972; Q3SYL3; Q6FH94; Q6P0L5"	"Clear cell renal cell carcinoma pathways; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"Neutrophil degranulation; Glycolysis; Gluconeogenesis"	"6"	"0"	"20.2"	"16.6"	"15.4"	"21.2"	"16.3"	"21.3"	"21.6"	"30.4"	"52.1"	"106.5"	"149.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61313"	"60S ribosomal protein L15 OS=Homo sapiens OX=9606 GN=RPL15 PE=1 SV=2"	"21"	"4"	"8"	"4"	"204"	"24.1"	"11.62"	"1515.38"	"12.70"	"4"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00827"	"6138"	"ENSG00000174748"	"RPL15"	"hsa:6138; P39030; P41051; P61313; Q5U0C0; Q642I1; Q6IPX6; Q8WYP2; Q96C44; Q9H2E5"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"222.0"	"252.7"	"194.2"	"185.1"	"210.4"	"213.3"	"268.2"	"416.7"	"705.4"	"1289.6"	"2158.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12931"	"Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3"	"7"	"4"	"8"	"3"	"704"	"80.1"	"8.21"	"1237.50"	"12.68"	"4"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00183, Pf02518"	"10131"	"ENSG00000126602"	"TRAP1"	"B4DR68; D3DUC8; F5H897; hsa:10131; O43642; O75235; Q12931; Q9UHL5"	"TNF-alpha signaling pathway; Clock-controlled autophagy in bone metabolism"	"Respiratory electron transport"	"3"	"0"	"86.0"	"101.9"	"108.8"	"89.5"	"123.0"	"114.5"	"142.1"	"166.3"	"340.5"	"663.8"	"823.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EI5"	"Transcription elongation factor A protein-like 4 OS=Homo sapiens OX=9606 GN=TCEAL4 PE=1 SV=2"	"19"	"4"	"9"	"4"	"215"	"24.6"	"5.20"	"1574.07"	"12.68"	"4"	"4"	""	"nucleus"	""	"Pf04538"	"79921"	"ENSG00000133142"	"TCEAL4"	"hsa:79921; Q8WY12; Q96EI5; Q9H2H1; Q9H775"	""	""	"0"	"0"	"397.1"	"331.2"	"445.6"	"444.2"	"477.0"	"454.6"	"466.7"	"554.9"	"1200.2"	"1513.6"	"1641.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13451"	"Peptidyl-prolyl cis-trans isomerase FKBP5 OS=Homo sapiens OX=9606 GN=FKBP5 PE=1 SV=2"	"12"	"3"	"5"	"3"	"457"	"51.2"	"5.90"	"817.57"	"12.67"	"2"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00254, Pf00515"	"2289"	"ENSG00000096060"	"FKBP5"	"F5H7R1; hsa:2289; Q13451; Q59EB8; Q5TGM6"	"Androgen receptor network in prostate cancer; Farnesoid X receptor pathway; Nuclear receptors meta-pathway; MECP2 and associated Rett syndrome"	"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; ESR-mediated signaling; MECP2 regulates neuronal receptors and channels"	"7"	"0"	"44.4"	"51.2"	"61.6"	"41.4"	"61.8"	"55.8"	"62.1"	"87.8"	"126.9"	"310.7"	"707.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13151"	"Heterogeneous nuclear ribonucleoprotein A0 OS=Homo sapiens OX=9606 GN=HNRNPA0 PE=1 SV=1"	"10"	"4"	"19"	"2"	"305"	"30.8"	"9.29"	"4527.63"	"12.65"	"4"	"3"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"10949"	"ENSG00000177733"	"HNRNPA0"	"hsa:10949; Q13151; Q6IB18"	""	""	"0"	"0"	"494.2"	"460.0"	"474.7"	"425.5"	"435.7"	"446.2"	"537.3"	"580.8"	"704.1"	"1034.0"	"1455.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30050"	"60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1"	"24"	"4"	"10"	"4"	"165"	"17.8"	"9.42"	"2048.87"	"12.62"	"4"	"3"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00298, Pf03946"	"6136"	"ENSG00000197958"	"RPL12"	"hsa:6136; P30050; Q5VVV2; Q6PB27"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"734.8"	"817.7"	"894.2"	"658.3"	"777.0"	"779.1"	"1013.2"	"1501.1"	"2142.0"	"3668.8"	"5509.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4J8"	"Dystrobrevin alpha OS=Homo sapiens OX=9606 GN=DTNA PE=1 SV=2"	"7"	"5"	"8"	"3"	"743"	"83.8"	"6.89"	"1566.64"	"12.62"	"4"	"4"	"cell-cell signaling;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00569, Pf09068, Pf09069"	"1837"	"ENSG00000134769"	"DTNA"	"A8K541; A8MSZ0; A8MUY4; B4DGS6; B4DIR0; B4DIU8; hsa:1837; M0QYX6; M0R397; O15332; O15333; O75697; Q13197; Q13198; Q13199; Q13498; Q13499; Q13500; Q59GK7; Q9BS59; Q9Y4J8"	"13q12.12 copy number variation"	""	"1"	"2"	"265.7"	"222.5"	"296.8"	"256.2"	"279.1"	"265.1"	"336.9"	"509.9"	"966.3"	"1547.1"	"1930.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62913"	"60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2"	"17"	"3"	"7"	"3"	"178"	"20.2"	"9.60"	"1423.26"	"12.60"	"3"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00281, Pf00673"	"6135"	"ENSG00000142676"	"RPL11"	"hsa:6135; P25121; P39026; P62913; Q8TDH2; Q9Y674"	"Cytoplasmic ribosomal proteins"	"GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"445.2"	"476.2"	"488.6"	"395.8"	"424.8"	"434.8"	"565.6"	"664.7"	"1044.7"	"1390.1"	"1727.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TDN6"	"Ribosome biogenesis protein BRX1 homolog OS=Homo sapiens OX=9606 GN=BRIX1 PE=1 SV=2"	"10"	"3"	"7"	"3"	"353"	"41.4"	"9.92"	"1039.98"	"12.56"	"2"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf04427"	"55299"	"ENSG00000113460"	"BRIX1"	"A8K0P5; hsa:55299; Q3ZTT4; Q8N453; Q8TDN6; Q96DH1"	"Gastric cancer network 2"	""	"1"	"0"	"37.1"	"30.9"	"47.6"	"34.8"	"41.8"	"36.6"	"44.1"	"70.3"	"157.6"	"271.7"	"468.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13618"	"Cullin-3 OS=Homo sapiens OX=9606 GN=CUL3 PE=1 SV=2"	"6"	"4"	"8"	"4"	"768"	"88.9"	"8.48"	"1334.67"	"12.54"	"4"	"4"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00888, Pf10557"	"8452"	"ENSG00000036257"	"CUL3"	"A8K536; B8ZZC3; hsa:8452; O75415; Q13618; Q569L3; Q9UBI8; Q9UET7"	"Hedgehog signaling pathway; NRF2-ARE regulation; 22q11.2 copy number variation syndrome; Head and neck squamous cell carcinoma; 1p36 copy number variation syndrome"	"Hedgehog 'on' state; Potential therapeutics for SARS; Antigen processing: Ubiquitination & Proteasome degradation; Degradation of DVL; Regulation of RAS by GAPs; Neddylation; KEAP1-NFE2L2 pathway; RHOBTB3 ATPase cycle; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle"	"15"	"0"	"105.7"	"122.0"	"131.7"	"121.1"	"147.7"	"145.8"	"171.7"	"280.8"	"884.5"	"1406.8"	"1760.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BW85"	"Splicing factor YJU2 OS=Homo sapiens OX=9606 GN=YJU2 PE=1 SV=1"	"10"	"2"	"5"	"2"	"323"	"37.1"	"5.92"	"1685.02"	"12.54"	"2"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf04502"	"55702"	"ENSG00000105248"	"YJU2"	"hsa:55702; O75270; Q9BW85; Q9H862; Q9NW16"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"210.1"	"147.6"	"224.1"	"223.7"	"228.7"	"231.6"	"255.7"	"292.6"	"380.1"	"870.9"	"1859.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75122"	"CLIP-associating protein 2 OS=Homo sapiens OX=9606 GN=CLASP2 PE=1 SV=3"	"4"	"4"	"8"	"3"	"1294"	"141.0"	"8.40"	"1523.61"	"12.51"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf12348"	"23122"	"ENSG00000163539"	"CLASP2"	"B2RTR1; F5H604; hsa:23122; O75122; Q7L8F6; Q8N6R6; Q9BQT3; Q9BQT4; Q9H7A3; Q9NSZ2"	"7q11.23 copy number variation syndrome"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Role of ABL in ROBO-SLIT signaling"	"8"	"1"	"65.3"	"57.8"	"64.9"	"56.3"	"58.7"	"67.3"	"84.1"	"88.0"	"117.0"	"224.6"	"290.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16656"	"Nuclear respiratory factor 1 OS=Homo sapiens OX=9606 GN=NRF1 PE=1 SV=1"	"5"	"2"	"6"	"2"	"503"	"53.5"	"5.05"	"1433.44"	"12.49"	"2"	"2"	"other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf10491"	"4899"	"ENSG00000106459"	"NRF1"	"A8K4C6; B4DDV6; hsa:4899; Q15305; Q16656; Q96AN2"	"Energy metabolism; Interactions between LOXL4 and oxidative stress pathway; Mitochondrial gene expression; Sildenafil treatment"	"PPARA activates gene expression; Transcriptional activation of mitochondrial biogenesis"	"6"	"0"	"141.1"	"144.0"	"146.6"	"122.2"	"143.8"	"128.5"	"174.7"	"222.2"	"359.1"	"814.0"	"1809.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15003"	"Condensin complex subunit 2 OS=Homo sapiens OX=9606 GN=NCAPH PE=1 SV=3"	"5"	"4"	"8"	"4"	"741"	"82.5"	"5.06"	"1283.51"	"12.48"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf05786"	"23397"	"ENSG00000121152"	"NCAPH"	"B4E189; hsa:23397; Q15003; Q8TB87"	"2q11.2 copy number variation syndrome"	"Condensation of Prometaphase Chromosomes"	"2"	"0"	"313.8"	"232.6"	"358.5"	"312.8"	"357.2"	"327.7"	"398.4"	"468.3"	"931.6"	"1642.5"	"2237.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52789"	"Hexokinase-2 OS=Homo sapiens OX=9606 GN=HK2 PE=1 SV=2"	"5"	"4"	"8"	"3"	"917"	"102.3"	"6.05"	"1368.93"	"12.47"	"4"	"4"	"cell organization and biogenesis;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;other cell component"	"kinase activity;other molecular function"	"Pf00349, Pf03727"	"3099"	"ENSG00000159399"	"HK2"	"D6W5J2; hsa:3099; P52789; Q8WU87; Q9UN82"	"Clear cell renal cell carcinoma pathways; Warburg effect modulated by deubiquitinating enzymes and their substrates; Glycolysis and gluconeogenesis; A network map of Macrophage-stimulating protein (MSP) signaling; Metabolic Epileptic Disorders; UDP-derived sugars synthesis in fibroblasts"	"Glycolysis"	"7"	"0"	"135.2"	"117.5"	"140.4"	"129.2"	"151.0"	"135.5"	"168.6"	"232.9"	"929.8"	"2113.0"	"3263.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P17480"	"Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF PE=1 SV=1"	"3"	"2"	"6"	"2"	"764"	"89.4"	"5.81"	"1197.50"	"12.44"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00505, Pf09011, Pf14887"	"7343"	"ENSG00000108312"	"UBTF"	"A8K6R8; hsa:7343; P17480"	"Ectoderm differentiation"	"NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; RNA Polymerase I Promoter Opening"	"6"	"0"	"174.7"	"171.3"	"161.0"	"166.7"	"184.3"	"187.2"	"209.8"	"267.2"	"526.9"	"616.5"	"609.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92598"	"Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1"	"5"	"4"	"7"	"2"	"858"	"96.8"	"5.39"	"949.35"	"12.44"	"3"	"4"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00012"	"10808"	"ENSG00000120694"	"HSPH1"	"B4DYH1; hsa:10808; O95739; Q5TBM6; Q5TBM7; Q5TBM8; Q92598; Q9UPC4"	""	"Regulation of HSF1-mediated heat shock response; Scavenging by Class F Receptors"	"2"	"0"	"130.8"	"139.7"	"146.8"	"140.7"	"148.1"	"141.4"	"173.0"	"234.0"	"349.3"	"636.1"	"933.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P16949"	"Stathmin OS=Homo sapiens OX=9606 GN=STMN1 PE=1 SV=3"	"22"	"3"	"8"	"3"	"149"	"17.3"	"5.97"	"1339.96"	"12.43"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf00836"	"3925"	"ENSG00000117632"	"STMN1"	"A2A2D1; B2R4E7; B7Z8N4; D3DPJ5; hsa:3925; P16949"	"Microtubule cytoskeleton regulation; Retinoblastoma gene in cancer; RAC1/PAK1/p38/MMP2 pathway; MAPK signaling pathway; EGF/EGFR signaling pathway; IL-18 signaling pathway"	"Nuclear signaling by ERBB4"	"7"	"0"	"262.4"	"238.2"	"315.3"	"305.5"	"276.3"	"290.0"	"326.8"	"393.0"	"472.3"	"832.8"	"2427.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62241"	"40S ribosomal protein S8 OS=Homo sapiens OX=9606 GN=RPS8 PE=1 SV=2"	"22"	"4"	"7"	"4"	"208"	"24.2"	"10.32"	"894.13"	"12.43"	"3"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01201"	"6202"	"ENSG00000142937"	"RPS8"	"hsa:6202; P09058; P62241; Q6IRL7"	"Cytoplasmic ribosomal proteins"	"Major pathway of rRNA processing in the nucleolus and cytosol; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"422.8"	"405.3"	"383.7"	"324.3"	"394.9"	"353.4"	"474.4"	"586.9"	"724.0"	"1182.5"	"1771.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKM9"	"RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1"	"12"	"4"	"9"	"4"	"306"	"32.4"	"9.17"	"1717.38"	"12.39"	"4"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00076"	"22913"	"ENSG00000125970"	"RALY"	"hsa:22913; Q14621; Q2M365; Q5QPL8; Q9BQX6; Q9UJE3; Q9UKM9"	""	""	"0"	"0"	"490.0"	"444.0"	"554.0"	"437.4"	"503.4"	"497.2"	"614.4"	"804.1"	"1311.4"	"2010.0"	"3127.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y237"	"Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 OS=Homo sapiens OX=9606 GN=PIN4 PE=1 SV=1"	"31"	"4"	"8"	"4"	"131"	"13.8"	"9.77"	"1190.07"	"12.38"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13616"	"5303"	"ENSG00000102309"	"PIN4"	"A8E0G6; B3KXM0; F5H1P5; hsa:5303; Q0D2H3; Q3MHV0; Q52M21; Q5HYW6; Q6IRW4; Q9Y237"	""	""	"0"	"0"	"549.8"	"519.9"	"542.5"	"388.4"	"455.3"	"544.0"	"775.4"	"857.0"	"1149.1"	"1762.6"	"2060.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99661"	"Kinesin-like protein KIF2C OS=Homo sapiens OX=9606 GN=KIF2C PE=1 SV=2"	"7"	"3"	"4"	"3"	"725"	"81.3"	"7.83"	"495.65"	"12.38"	"1"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00225"	"11004"	"ENSG00000142945"	"KIF2C"	"B3ITR9; hsa:11004; Q5JR88; Q6ICU1; Q96C18; Q96HB8; Q99661; Q9BWV8"	"Microtubule cytoskeleton regulation"	"COPI-dependent Golgi-to-ER retrograde traffic; Kinesins; Separation of Sister Chromatids; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"10"	"0"	"64.7"	"71.1"	"80.6"	"66.3"	"65.5"	"73.4"	"90.6"	"135.4"	"279.2"	"391.3"	"417.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BTE3"	"Mini-chromosome maintenance complex-binding protein OS=Homo sapiens OX=9606 GN=MCMBP PE=1 SV=2"	"7"	"3"	"6"	"3"	"642"	"72.9"	"5.87"	"1294.26"	"12.38"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf09739"	"79892"	"ENSG00000197771"	"MCMBP"	"B3KSP7; hsa:79892; Q6IA56; Q9BTE3; Q9BVT9; Q9H916"	""	""	"0"	"0"	"127.8"	"139.6"	"114.8"	"112.8"	"124.5"	"127.2"	"153.9"	"184.5"	"339.8"	"832.7"	"1081.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60313"	"Dynamin-like 120 kDa protein, mitochondrial OS=Homo sapiens OX=9606 GN=OPA1 PE=1 SV=3"	"5"	"4"	"7"	"4"	"960"	"111.6"	"7.87"	"784.65"	"12.34"	"3"	"4"	"cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00350, Pf19434"	"4976"	"ENSG00000198836"	"OPA1"	"D3DNW4; E5KLJ5; E5KLJ6; E5KLJ7; E5KLK1; E5KLK2; hsa:4976; O60313"	"Orexin receptor pathway"	"Regulation of Apoptosis"	"2"	"0"	"91.9"	"89.4"	"121.3"	"86.6"	"104.6"	"105.9"	"117.4"	"151.6"	"355.7"	"808.1"	"1142.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P38432"	"Coilin OS=Homo sapiens OX=9606 GN=COIL PE=1 SV=1"	"7"	"3"	"6"	"3"	"576"	"62.6"	"9.07"	"1128.60"	"12.33"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf15862"	"8161"	"ENSG00000121058"	"COIL"	"B2R931; hsa:8161; P38432"	""	""	"0"	"0"	"319.4"	"290.4"	"324.8"	"279.5"	"320.0"	"333.5"	"398.5"	"484.2"	"1140.1"	"1332.8"	"1518.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P18859"	"ATP synthase-coupling factor 6, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PF PE=1 SV=1"	"36"	"2"	"3"	"2"	"108"	"12.6"	"9.52"	"380.50"	"12.31"	"1"	"2"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf05511"	"522"	"ENSG00000154723"	"ATP5PF"	"hsa:522; J3KQ83; P18859"	"Electron transport chain: OXPHOS system in mitochondria; Oxidative phosphorylation"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"4"	"0"	"99.6"	"85.3"	"86.0"	"84.7"	"111.7"	"90.5"	"123.2"	"138.5"	"182.1"	"313.1"	"431.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7RTV0"	"PHD finger-like domain-containing protein 5A OS=Homo sapiens OX=9606 GN=PHF5A PE=1 SV=1"	"39"	"4"	"6"	"4"	"110"	"12.4"	"8.41"	"560.55"	"12.29"	"2"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03660"	"84844"	"ENSG00000100410"	"PHF5A"	"hsa:84844; Q7RTV0; Q9UH06"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"605.3"	"494.7"	"533.7"	"464.3"	"527.9"	"554.1"	"654.3"	"707.5"	"879.9"	"1637.8"	"2880.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2A7"	"Nck-associated protein 1 OS=Homo sapiens OX=9606 GN=NCKAP1 PE=1 SV=1"	"4"	"5"	"9"	"4"	"1128"	"128.7"	"6.62"	"1800.79"	"12.26"	"5"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	""	"Pf09735"	"10787"	"ENSG00000061676"	"NCKAP1"	"hsa:10787; O60329; Q53QN5; Q53S94; Q53Y35; Q9Y2A7"	"Exercise-induced circadian regulation; Regulation of actin cytoskeleton"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; VEGFA-VEGFR2 Pathway"	"9"	"1"	"353.3"	"284.4"	"379.3"	"342.9"	"384.6"	"335.7"	"422.2"	"628.7"	"1448.2"	"2289.3"	"2626.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99497"	"Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2"	"28"	"3"	"5"	"3"	"189"	"19.9"	"6.79"	"831.47"	"12.26"	"2"	"3"	"cell-cell signaling;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf01965"	"11315"	"ENSG00000116288"	"PARK7"	"B2R4Z1; hsa:11315; O14805; Q6DR95; Q7LFU2; Q99497"	"Androgen receptor signaling pathway; Synaptic vesicle pathway; Parkinson's disease pathway"	"Late endosomal microautophagy; Aggrephagy; SUMOylation of transcription cofactors; Chaperone Mediated Autophagy"	"7"	"0"	"210.4"	"179.8"	"203.7"	"177.0"	"195.1"	"206.2"	"258.1"	"308.0"	"395.8"	"417.8"	"507.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P02533"	"Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4"	"10"	"6"	"11"	"2"	"472"	"51.5"	"5.16"	"2339.57"	"12.21"	"6"	"4"	"cell organization and biogenesis;other biological processes"	"plasma membrane;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00038"	"3861"	"ENSG00000186847"	"KRT14"	"hsa:3861; P02533; Q14715; Q53XY3; Q9BUE3; Q9UBN2; Q9UBN3; Q9UCY4"	"Corticotropin-releasing hormone signaling pathway"	"Formation of the cornified envelope; Type I hemidesmosome assembly"	"4"	"0"	"64.0"	"97.5"	"107.1"	"87.6"	"160.3"	"91.6"	"126.9"	"156.1"	"176.6"	"785.0"	"469.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19784"	"Casein kinase II subunit alpha' OS=Homo sapiens OX=9606 GN=CSNK2A2 PE=1 SV=1"	"15"	"5"	"7"	"4"	"350"	"41.2"	"8.56"	"874.01"	"12.21"	"3"	"4"	"cell-cell signaling;cell cycle OR cell proliferation;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"1459"	"ENSG00000070770"	"CSNK2A2"	"hsa:1459; P19784"	"Alzheimer's disease and miRNA effects; Allograft rejection; lncRNA in canonical Wnt signaling and colorectal cancer; Breast cancer pathway; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Measles virus infection; Pleural mesothelioma; Alzheimer's disease"	"Regulation of PTEN stability and activity; KEAP1-NFE2L2 pathway; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Regulation of TP53 Activity through Phosphorylation; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; WNT mediated activation of DVL; Signal transduction by L1; Receptor Mediated Mitophagy; Condensation of Prometaphase Chromosomes; Synthesis of PC"	"19"	"0"	"140.6"	"176.4"	"154.2"	"134.0"	"148.4"	"157.5"	"210.2"	"271.2"	"387.8"	"1013.9"	"1759.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3E1"	"Hepatoma-derived growth factor-related protein 3 OS=Homo sapiens OX=9606 GN=HDGFL3 PE=1 SV=1"	"22"	"3"	"5"	"3"	"203"	"22.6"	"7.99"	"855.94"	"12.21"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus"	"signal transduction activity or receptor binding;cytoskeletal activity"	"Pf00855"	"50810"	"ENSG00000166503"	"HDGFL3"	"hsa:50810; Q9Y3E1"	""	""	"0"	"0"	"189.1"	"177.4"	"208.2"	"192.4"	"208.8"	"217.7"	"233.0"	"269.2"	"1530.6"	"2278.0"	"2318.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P36542"	"ATP synthase subunit gamma, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1C PE=1 SV=1"	"14"	"4"	"9"	"4"	"298"	"33.0"	"9.22"	"1294.75"	"12.19"	"4"	"3"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf00231"	"509"	"ENSG00000165629"	"ATP5F1C"	"A8KA31; hsa:509; P36542; Q5VYP3; Q6I9V2; Q96AS8"	"Electron transport chain: OXPHOS system in mitochondria"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"3"	"0"	"113.9"	"128.4"	"117.6"	"100.2"	"119.9"	"136.1"	"152.5"	"212.5"	"456.2"	"1126.8"	"1820.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96MU7"	"YTH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=YTHDC1 PE=1 SV=3"	"7"	"3"	"5"	"3"	"727"	"84.6"	"6.23"	"861.70"	"12.16"	"2"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;nucleus"	"nucleic acid binding activity"	"Pf04146"	"91746"	"ENSG00000083896; ENSG00000275272"	"YTHDC1"	"hsa:91746; Q4W5Q3; Q7Z622; Q8TF35; Q96MU7"	""	""	"0"	"0"	"324.4"	"301.6"	"270.5"	"286.4"	"301.3"	"294.2"	"366.4"	"494.8"	"674.7"	"954.7"	"1285.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9ULP9"	"TBC1 domain family member 24 OS=Homo sapiens OX=9606 GN=TBC1D24 PE=1 SV=2"	"6"	"3"	"6"	"3"	"559"	"62.9"	"7.36"	"1250.77"	"12.12"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;other cell component"	"enzyme regulator activity"	"Pf00566, Pf07534"	"57465"	"ENSG00000162065"	"TBC1D24"	"A0JNW3; B9A6M6; hsa:57465; Q2KJ08; Q9ULP9"	""	"TBC/RABGAPs"	"1"	"0"	"53.7"	"53.2"	"67.0"	"59.7"	"68.9"	"88.5"	"172.0"	"476.1"	"1266.0"	"1491.2"	"1749.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63151"	"Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R2A PE=1 SV=1"	"12"	"4"	"8"	"4"	"447"	"51.7"	"6.20"	"1128.25"	"12.11"	"4"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity"	""	"5520"	"ENSG00000221914"	"PPP2R2A"	"B2RBU8; B4E1T7; hsa:5520; P50409; P63151; Q00007"	"Wnt signaling pathway and pluripotency; PI3K-Akt signaling pathway; Glycogen synthesis and degradation"	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Cyclin D associated events in G1; Cyclin A/B1/B2 associated events during G2/M transition; Initiation of Nuclear Envelope (NE) Reformation"	"7"	"0"	"95.7"	"82.5"	"130.0"	"107.7"	"122.5"	"115.7"	"132.0"	"185.5"	"309.2"	"476.1"	"821.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13356"	"RING-type E3 ubiquitin-protein ligase PPIL2 OS=Homo sapiens OX=9606 GN=PPIL2 PE=1 SV=1"	"8"	"4"	"7"	"4"	"520"	"58.8"	"8.78"	"1058.34"	"12.11"	"3"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00160"	"23759"	"ENSG00000100023"	"PPIL2"	"hsa:23759; Q13356; Q13357; Q8TAH2; Q9BWR8"	""	"mRNA Splicing - Major Pathway; Basigin interactions"	"2"	"0"	"324.3"	"270.4"	"347.2"	"291.7"	"353.0"	"333.7"	"404.1"	"377.7"	"618.1"	"1088.6"	"1525.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5T8P6"	"RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3"	"5"	"5"	"8"	"5"	"1007"	"113.5"	"9.16"	"1228.92"	"12.09"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf01480"	"64062"	"ENSG00000139746"	"RBM26"	"B4DZE0; hsa:64062; Q2NKM2; Q2NKQ2; Q5CZH8; Q5T8P5; Q5T8P6; Q5T8P8; Q5U5P5; Q5W0G7; Q8N3H5; Q96K92; Q96SZ3; Q9H2F8; Q9H7F9; Q9P1G7"	""	""	"0"	"0"	"224.7"	"222.5"	"235.0"	"192.3"	"259.9"	"213.7"	"267.6"	"339.9"	"599.3"	"1168.4"	"1795.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92905"	"COP9 signalosome complex subunit 5 OS=Homo sapiens OX=9606 GN=COPS5 PE=1 SV=4"	"13"	"4"	"6"	"4"	"334"	"37.6"	"6.54"	"643.71"	"12.07"	"2"	"4"	"protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01398, Pf18323"	"10987"	"ENSG00000121022"	"COPS5"	"hsa:10987; O15386; Q6AW95; Q86WQ4; Q92905; Q9BQ17"	""	"Formation of TC-NER Pre-Incision Complex; Cargo recognition for clathrin-mediated endocytosis; Neddylation; DNA Damage Recognition in GG-NER"	"4"	"0"	"40.9"	"34.9"	"59.4"	"36.4"	"50.6"	"60.0"	"79.4"	"127.6"	"449.9"	"1220.6"	"2353.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49327"	"Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3"	"2"	"3"	"5"	"3"	"2511"	"273.3"	"6.44"	"741.72"	"12.05"	"2"	"3"	"other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00107, Pf00109, Pf00550, Pf00698, Pf00975, Pf02801, Pf08242, Pf08659, Pf14765, Pf16197"	"2194"	"ENSG00000169710"	"FASN"	"hsa:2194; P49327; Q13479; Q16702; Q4LE83; Q6P4U5; Q6SS02; Q969R1; Q96C68; Q96IT0"	"AMP-activated protein kinase signaling; Sterol regulatory element-binding proteins (SREBP) signaling; SREBF and miR33 in cholesterol and lipid homeostasis; Liver X receptor pathway; Nuclear receptors meta-pathway; Fatty acid biosynthesis; Angiopoietin-like protein 8 regulatory pathway; Lipid metabolism pathway; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Omega-9 fatty acid synthesis; FOXA2 pathway"	"ChREBP activates metabolic gene expression; Activation of gene expression by SREBF (SREBP); Fatty acyl-CoA biosynthesis; NR1H2 & NR1H3 regulate gene expression linked to lipogenesis; Vitamin B5 (pantothenate) metabolism"	"18"	"0"	"40.1"	"38.7"	"53.1"	"41.1"	"49.5"	"36.1"	"52.2"	"65.0"	"124.6"	"210.6"	"384.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86VN1"	"Vacuolar protein-sorting-associated protein 36 OS=Homo sapiens OX=9606 GN=VPS36 PE=1 SV=1"	"8"	"4"	"8"	"4"	"386"	"43.8"	"7.20"	"1455.85"	"12.02"	"4"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport"	"other membranes;cytosol;nucleus;other cytoplasmic organelle"	"other molecular function"	"Pf04157, Pf11605"	"51028"	"ENSG00000136100"	"VPS36"	"A8K125; hsa:51028; Q3ZCV7; Q5H9S1; Q5VXB6; Q86VN1; Q9H8Z5; Q9Y3E3"	"Network map of SARS-CoV-2 signaling pathway"	"Endosomal Sorting Complex Required For Transport (ESCRT); HCMV Late Events"	"3"	"0"	"78.5"	"86.5"	"112.1"	"79.6"	"138.2"	"159.6"	"212.2"	"420.6"	"905.0"	"1577.1"	"1926.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13155"	"Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 OS=Homo sapiens OX=9606 GN=AIMP2 PE=1 SV=2"	"19"	"3"	"5"	"3"	"320"	"35.3"	"8.22"	"743.00"	"12.01"	"2"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf14497, Pf16780, Pf18569"	"7965"	"ENSG00000106305"	"AIMP2"	"F8W950; hsa:7965; Q13155; Q75MR1; Q96CZ5; Q9P1L2"	"Osteoclast signaling; Transcriptional activation by NRF2 in response to phytochemicals; NRF2-ARE regulation"	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"5"	"0"	"47.7"	"34.0"	"57.7"	"55.5"	"58.2"	"57.1"	"61.1"	"87.4"	"258.5"	"537.5"	"748.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99873"	"Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3"	"10"	"3"	"6"	"3"	"371"	"42.4"	"5.35"	"1273.28"	"11.99"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13649"	"3276"	"ENSG00000126457"	"PRMT1"	"A0A087X1W2; B4E3C3; G5E9B6; H7C2I1; hsa:3276; Q15529; Q2VP93; Q6LEU5; Q8WUW5; Q99872; Q99873; Q99874; Q9NZ04; Q9NZ05; Q9NZ06"	"Energy metabolism; mRNA processing; Nitric oxide metabolism in cystic fibrosis; 16p11.2 distal deletion syndrome; Interferon type I signaling pathways"	"Estrogen-dependent gene expression; Extra-nuclear estrogen signaling; RMTs methylate histone arginines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Maturation of nucleoprotein"	"11"	"0"	"35.2"	"33.0"	"41.4"	"44.2"	"49.4"	"31.9"	"55.1"	"77.3"	"132.6"	"428.2"	"1094.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NQ48"	"Leucine zipper transcription factor-like protein 1 OS=Homo sapiens OX=9606 GN=LZTFL1 PE=1 SV=1"	"8"	"2"	"4"	"2"	"299"	"34.6"	"5.36"	"383.56"	"11.97"	"1"	"2"	"other biological processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf15294"	"54585"	"ENSG00000163818"	"LZTFL1"	"B3KSI9; B4E0K7; hsa:54585; Q8TC61; Q9NQ48; Q9NQ56"	"Ciliary landscape; Genes related to primary cilium development (based on CRISPR); Ciliopathies; Bardet-Biedl syndrome"	"BBSome-mediated cargo-targeting to cilium"	"5"	"0"	"30.2"	"30.7"	"40.4"	"41.2"	"45.0"	"38.4"	"43.3"	"68.5"	"140.0"	"685.3"	"1288.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H3U1"	"Protein unc-45 homolog A OS=Homo sapiens OX=9606 GN=UNC45A PE=1 SV=1"	"5"	"3"	"4"	"3"	"944"	"103.0"	"6.07"	"438.08"	"11.96"	"1"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf11701, Pf13181, Pf13432"	"55898"	"ENSG00000140553"	"UNC45A"	"A8K6F7; hsa:55898; Q7L3Y6; Q9H3U1; Q9H3U8; Q9NSE8; Q9NSE9"	""	""	"0"	"0"	"76.2"	"59.2"	"100.5"	"85.6"	"99.8"	"98.1"	"99.3"	"151.9"	"319.5"	"782.9"	"1184.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62888"	"60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2"	"20"	"2"	"7"	"2"	"115"	"12.8"	"9.63"	"1127.51"	"11.95"	"2"	"2"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01248"	"6156"	"ENSG00000156482"	"RPL30"	"B2R591; hsa:6156; P04645; P62888; Q502Z6"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"35.8"	"53.8"	"42.9"	"40.5"	"57.3"	"53.0"	"68.4"	"90.8"	"225.7"	"521.2"	"917.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P18621"	"60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3"	"22"	"4"	"8"	"4"	"184"	"21.4"	"10.17"	"1392.65"	"11.93"	"3"	"4"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf00237"	"6139"	"ENSG00000265681"	"RPL17"	"B2R4H3; B4E3C2; B5ME31; hsa:6139; J3QL51; P18621; Q3KQW2; Q6NZ54; Q7M4M5"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"513.7"	"496.6"	"564.8"	"460.5"	"549.3"	"493.2"	"664.8"	"860.5"	"1245.2"	"2003.7"	"2903.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q00013"	"55 kDa erythrocyte membrane protein OS=Homo sapiens OX=9606 GN=MPP1 PE=1 SV=2"	"11"	"4"	"8"	"4"	"466"	"52.3"	"7.37"	"1302.88"	"11.92"	"4"	"4"	"other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;kinase activity"	"Pf00018, Pf00595, Pf00625"	"4354"	"ENSG00000130830"	"MPP1"	"B4DZV5; G3XAI1; hsa:4354; Q00013; Q2TSB6; Q5J7V5"	"MECP2 and associated Rett syndrome"	"Sensory processing of sound by outer hair cells of the cochlea"	"2"	"0"	"92.3"	"88.8"	"93.1"	"81.8"	"98.2"	"81.2"	"106.3"	"142.8"	"580.1"	"1179.2"	"1569.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HCC0"	"Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC2 PE=1 SV=1"	"9"	"5"	"8"	"5"	"563"	"61.3"	"7.68"	"1569.95"	"11.91"	"4"	"4"	"other metabolic processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf01039"	"64087"	"ENSG00000131844"	"MCCC2"	"A6NIY9; hsa:64087; Q96C27; Q9HCC0; Q9Y4L7"	""	"Biotin transport and metabolism; Branched-chain amino acid catabolism; Defective HLCS causes multiple carboxylase deficiency"	"3"	"0"	"550.2"	"594.8"	"481.6"	"506.2"	"547.8"	"567.9"	"610.0"	"794.2"	"1078.6"	"1625.4"	"2102.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q49A26"	"Putative oxidoreductase GLYR1 OS=Homo sapiens OX=9606 GN=GLYR1 PE=1 SV=4"	"7"	"3"	"6"	"3"	"553"	"60.5"	"9.17"	"1186.73"	"11.90"	"3"	"3"	"cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00855, Pf03446, Pf14833"	"84656"	"ENSG00000140632"	"GLYR1"	"B4DL47; C9JJ40; C9JJ60; hsa:84656; Q49A26; Q5U632; Q6P1Q2; Q6V3W7; Q9BTI1; Q9BXK2"	""	""	"0"	"0"	"58.1"	"60.4"	"84.6"	"66.7"	"78.9"	"74.6"	"94.2"	"120.1"	"229.3"	"383.5"	"496.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P32969"	"60S ribosomal protein L9 OS=Homo sapiens OX=9606 GN=RPL9 PE=1 SV=1"	"22"	"3"	"6"	"3"	"192"	"21.9"	"9.95"	"1134.07"	"11.89"	"3"	"3"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00347"	"6133"	"ENSG00000163682"	"RPL9; RPL9P7; RPL9P8; RPL9P9"	"hsa:6133; P32969"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"121.5"	"105.9"	"132.6"	"119.7"	"147.7"	"132.8"	"157.1"	"222.4"	"355.5"	"603.4"	"883.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6NSI4"	"RPA-related protein RADX OS=Homo sapiens OX=9606 GN=RADX PE=1 SV=2"	"6"	"3"	"5"	"3"	"855"	"97.5"	"8.41"	"850.49"	"11.89"	"2"	"3"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf17659"	"55086"	"ENSG00000147231"	"RADX"	"H7BY89; hsa:55086; Q4G0L7; Q5JQS1; Q5JRF9; Q6NSI4; Q6PHY5; Q6PII9; Q6PJU8; Q9H7W5; Q9NWA6"	""	""	"0"	"0"	"68.7"	"61.7"	"69.7"	"61.8"	"71.7"	"76.4"	"89.2"	"121.1"	"204.3"	"349.4"	"466.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKS6"	"Protein kinase C and casein kinase substrate in neurons protein 3 OS=Homo sapiens OX=9606 GN=PACSIN3 PE=1 SV=2"	"9"	"4"	"7"	"4"	"424"	"48.5"	"6.18"	"1551.09"	"11.88"	"4"	"3"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00611, Pf14604"	"29763"	"ENSG00000165912"	"PACSIN3"	"A6NH84; hsa:29763; Q9H331; Q9NWV9; Q9UKS6"	""	"Clathrin-mediated endocytosis"	"1"	"0"	"206.7"	"167.5"	"216.5"	"182.5"	"217.5"	"209.8"	"228.9"	"286.1"	"629.6"	"1655.0"	"2383.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NUQ3"	"Gamma-taxilin OS=Homo sapiens OX=9606 GN=TXLNG PE=1 SV=2"	"9"	"4"	"7"	"3"	"528"	"60.5"	"7.52"	"1338.39"	"11.84"	"4"	"3"	"cell cycle OR cell proliferation;other biological processes"	"other membranes;cytosol;nucleus"	"other molecular function"	"Pf09728"	"55787"	"ENSG00000086712"	"TXLNG"	"hsa:55787; Q2KQ75; Q5JNZ7; Q9NUQ3; Q9P0X1"	""	""	"0"	"0"	"80.9"	"80.0"	"93.6"	"70.2"	"95.5"	"94.7"	"118.4"	"188.0"	"505.8"	"921.1"	"1047.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08865"	"40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4"	"16"	"3"	"5"	"3"	"295"	"32.8"	"4.87"	"718.33"	"11.82"	"2"	"3"	"cell adhesion;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;translational apparatus;nucleus;other cell component"	"translation activity;other molecular function"	"Pf00318, Pf16122"	"3921"	"ENSG00000168028"	"RPSA"	"hsa:3921; P08865; P11085; P12030; Q16471; Q6IPD1; Q6IPD2; Q6NSD1; Q6NXQ8; Q86VC0"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"155.5"	"177.7"	"187.1"	"195.3"	"195.8"	"177.2"	"226.9"	"336.3"	"653.2"	"1171.6"	"1628.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60885"	"Bromodomain-containing protein 4 OS=Homo sapiens OX=9606 GN=BRD4 PE=1 SV=2"	"2"	"4"	"7"	"4"	"1362"	"152.1"	"9.19"	"1047.89"	"11.78"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00439, Pf17035, Pf17105"	"23476"	"ENSG00000141867"	"BRD4"	"hsa:23476; O60433; O60885; Q4G0X8; Q86YS8; Q96PD3"	"VEGFA-VEGFR2 signaling; 7q11.23 copy number variation syndrome"	"Potential therapeutics for SARS"	"3"	"0"	"326.5"	"265.6"	"337.4"	"278.4"	"301.2"	"330.6"	"388.4"	"440.4"	"684.1"	"1253.9"	"1588.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61254"	"60S ribosomal protein L26 OS=Homo sapiens OX=9606 GN=RPL26 PE=1 SV=1"	"26"	"4"	"10"	"4"	"145"	"17.2"	"10.55"	"1875.98"	"11.74"	"4"	"3"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00467, Pf16906"	"6154"	"ENSG00000161970"	"RPL26"	"B2R4F0; D3DTR8; hsa:6154; P61254; Q02877; Q6IPY2"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"15"	"0"	"570.9"	"544.6"	"504.2"	"478.7"	"568.6"	"594.7"	"687.9"	"790.7"	"1188.6"	"2106.7"	"3356.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75152"	"Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3"	"6"	"6"	"10"	"6"	"810"	"89.1"	"8.37"	"2083.61"	"11.70"	"6"	"4"	"other metabolic processes;transport"	"nucleus"	"other molecular function"	"Pf15663"	"9877"	"ENSG00000058673"	"ZC3H11A"	"hsa:9877; O75152; Q6AHY4; Q6AHY9; Q6AW79; Q6AWA1; Q6PJK4; Q86XZ7"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"3"	"0"	"475.0"	"397.4"	"477.8"	"413.4"	"453.5"	"465.6"	"519.1"	"604.4"	"705.4"	"1082.1"	"1491.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H2Y7"	"Zinc finger protein 106 OS=Homo sapiens OX=9606 GN=ZNF106 PE=1 SV=1"	"2"	"2"	"3"	"2"	"1883"	"208.8"	"7.15"	"502.01"	"11.67"	"1"	"2"	"signal transduction"	"other membranes;cytosol;nucleus"	"other molecular function"	"Pf00400"	"64397"	"ENSG00000103994"	"ZNF106"	"B4DZ40; E9PE29; hsa:64397; Q6NSD9; Q6PEK1; Q86T43; Q86T45; Q86T50; Q86T58; Q86TA9; Q96M37; Q9H2Y7; Q9H7B8"	""	""	"0"	"0"	"16.8"	"22.5"	"27.8"	"21.9"	"25.1"	"26.5"	"29.9"	"39.6"	"51.2"	"77.6"	"71.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z6E9"	"E3 ubiquitin-protein ligase RBBP6 OS=Homo sapiens OX=9606 GN=RBBP6 PE=1 SV=1"	"2"	"3"	"6"	"3"	"1792"	"201.4"	"9.64"	"999.82"	"11.67"	"3"	"3"	"protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf04564, Pf08783, Pf13696"	"5930"	"ENSG00000122257"	"RBBP6"	"hsa:5930; Q147T5; Q15290; Q6DKH4; Q6P4C2; Q6YNC9; Q7Z6E8; Q7Z6E9; Q8N0V2; Q96PH3; Q9H3I8; Q9H5M5; Q9NPX4"	""	"RHOBTB1 GTPase cycle; Antigen processing: Ubiquitination & Proteasome degradation"	"2"	"0"	"152.3"	"148.2"	"209.9"	"148.8"	"180.4"	"209.2"	"216.0"	"258.3"	"340.0"	"520.5"	"652.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P43487"	"Ran-specific GTPase-activating protein OS=Homo sapiens OX=9606 GN=RANBP1 PE=1 SV=1"	"22"	"3"	"4"	"3"	"201"	"23.3"	"5.29"	"403.97"	"11.66"	"1"	"3"	"transport;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00638"	"5902"	"ENSG00000099901"	"RANBP1"	"hsa:5902; P43487; Q53EY3"	"22q11.2 copy number variation syndrome"	"Rev-mediated nuclear export of HIV RNA"	"2"	"0"	"379.7"	"314.5"	"428.3"	"400.8"	"398.9"	"355.6"	"430.4"	"483.2"	"755.2"	"1372.6"	"2565.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WWH5"	"Probable tRNA pseudouridine synthase 1 OS=Homo sapiens OX=9606 GN=TRUB1 PE=1 SV=1"	"10"	"3"	"7"	"3"	"349"	"37.2"	"8.25"	"1000.40"	"11.66"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01509"	"142940"	"ENSG00000165832"	"TRUB1"	"B2R716; hsa:142940; Q53ES2; Q8WWH5"	""	""	"0"	"0"	"92.2"	"102.9"	"98.4"	"97.8"	"114.2"	"114.0"	"137.2"	"181.3"	"404.4"	"953.8"	"1467.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y376"	"Calcium-binding protein 39 OS=Homo sapiens OX=9606 GN=CAB39 PE=1 SV=1"	"12"	"4"	"5"	"4"	"341"	"39.8"	"6.89"	"406.53"	"11.64"	"1"	"4"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"non-structural extracellular;other membranes;cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;other molecular function"	"Pf08569"	"51719"	"ENSG00000135932"	"CAB39"	"A8K8L7; hsa:51719; Q9Y376"	"AMP-activated protein kinase signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Endochondral ossification; Endochondral ossification with skeletal dysplasias"	"Neutrophil degranulation; Energy dependent regulation of mTOR by LKB1-AMPK"	"6"	"0"	"67.5"	"56.4"	"94.7"	"91.6"	"98.3"	"85.3"	"114.3"	"181.5"	"441.4"	"1021.0"	"1799.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15511"	"Actin-related protein 2/3 complex subunit 5 OS=Homo sapiens OX=9606 GN=ARPC5 PE=1 SV=3"	"28"	"4"	"8"	"4"	"151"	"16.3"	"5.67"	"1639.73"	"11.63"	"4"	"3"	"cell organization and biogenesis;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf04699"	"10092"	"ENSG00000162704"	"ARPC5"	"A6NEC4; hsa:10092; O15511; Q6PG42"	"Pathogenic Escherichia coli infection; Regulation of actin cytoskeleton"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Neutrophil degranulation; Clathrin-mediated endocytosis; EPHB-mediated forward signaling"	"8"	"0"	"159.9"	"189.2"	"173.8"	"134.9"	"168.8"	"171.4"	"208.3"	"298.8"	"1252.9"	"2169.6"	"2892.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P28331"	"NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS1 PE=1 SV=3"	"5"	"4"	"7"	"4"	"727"	"79.4"	"6.23"	"806.55"	"11.61"	"3"	"4"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00384, Pf09326, Pf10588, Pf13510"	"4719"	"ENSG00000023228; ENSG00000283447"	"NDUFS1"	"B4DIN9; B4DJA0; B4DPG1; B4DUC1; E7ENF3; hsa:4719; P28331; Q53TR8; Q8N1C4; Q8TCC9"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"124.3"	"97.0"	"139.5"	"104.9"	"132.2"	"119.5"	"140.6"	"226.0"	"615.9"	"1344.5"	"1843.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82664"	"28S ribosomal protein S10, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS10 PE=1 SV=2"	"16"	"2"	"4"	"2"	"201"	"23.0"	"8.00"	"1201.48"	"11.60"	"2"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	""	"Pf00338"	"55173"	"ENSG00000048544"	"MRPS10"	"B2RE89; hsa:55173; P82664; Q9H3E5; Q9NVR3"	""	"Mitochondrial translation elongation; Mitochondrial translation initiation; Mitochondrial translation termination"	"3"	"0"	"39.8"	"48.4"	"43.3"	"34.6"	"48.2"	"56.0"	"61.2"	"109.9"	"258.2"	"478.4"	"697.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49407"	"Beta-arrestin-1 OS=Homo sapiens OX=9606 GN=ARRB1 PE=1 SV=2"	"7"	"2"	"4"	"1"	"418"	"47.0"	"6.20"	"254.71"	"11.59"	"1"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00339, Pf02752"	"408"	"ENSG00000137486"	"ARRB1"	"B6V9G8; hsa:408; O75625; O75630; P49407; Q2PP20; Q9BTK8"	"Corticotropin-releasing hormone signaling pathway; Myometrial relaxation and contraction pathways; MAPK signaling pathway; Chemokine signaling pathway; Hedgehog signaling pathway; Gastrin signaling pathway; Kisspeptin/kisspeptin receptor system in the ovary; GPR143 in melanocytes and retinal pigment epithelium cells; Calcium regulation in cardiac cells"	"Ub-specific processing proteases; Activation of SMO; Activated NOTCH1 Transmits Signal to the Nucleus; G alpha (s) signalling events; Lysosome Vesicle Biogenesis; Golgi Associated Vesicle Biogenesis; Signaling by BRAF and RAF1 fusions; Thrombin signalling through proteinase activated receptors (PARs); Cargo recognition for clathrin-mediated endocytosis; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants"	"25"	"0"	"65.9"	"39.5"	"76.5"	"67.9"	"108.5"	"208.9"	"446.3"	"956.6"	"485.3"	"212.9"	"151.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NSY1"	"BMP-2-inducible protein kinase OS=Homo sapiens OX=9606 GN=BMP2K PE=1 SV=2"	"4"	"3"	"5"	"3"	"1161"	"129.1"	"6.51"	"717.82"	"11.58"	"2"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069, Pf15282"	"55589"	"ENSG00000138756"	"BMP2K"	"hsa:55589; O94791; Q4W5H2; Q8IYF2; Q8N2G7; Q8NHG9; Q9NSY1; Q9NTG8"	""	""	"0"	"0"	"44.8"	"35.1"	"68.4"	"51.5"	"63.2"	"63.7"	"65.8"	"77.9"	"127.9"	"150.2"	"157.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P28288"	"ATP-binding cassette sub-family D member 3 OS=Homo sapiens OX=9606 GN=ABCD3 PE=1 SV=1"	"6"	"4"	"8"	"3"	"659"	"75.4"	"9.36"	"905.06"	"11.58"	"2"	"4"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf00005, Pf06472"	"5825"	"ENSG00000117528"	"ABCD3"	"D3DT46; hsa:5825; P28288; Q15271; Q6NUN5; Q96DA3; Q9H529"	"Nuclear receptors in lipid metabolism and toxicity; Fragile X syndrome"	"RHOC GTPase cycle; RHOA GTPase cycle; Class I peroxisomal membrane protein import; ABC transporters in lipid homeostasis"	"6"	"1"	"219.6"	"201.1"	"246.3"	"197.6"	"217.4"	"212.6"	"254.7"	"328.0"	"775.5"	"1498.5"	"1954.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13177"	"Serine/threonine-protein kinase PAK 2 OS=Homo sapiens OX=9606 GN=PAK2 PE=1 SV=3"	"7"	"3"	"4"	"3"	"524"	"58.0"	"5.96"	"421.35"	"11.54"	"1"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069, Pf00786"	"5062"	"ENSG00000180370"	"PAK2"	"hsa:5062; Q13154; Q13177; Q6ISC3"	"Integrin-mediated cell adhesion; Apoptosis-related network due to altered Notch3 in ovarian cancer; Focal adhesion; Fas ligand pathway and stress induction of heat shock proteins; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Ras signaling; Pancreatic adenocarcinoma pathway; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-Merlin signaling dysregulation; Neural crest cell migration during development; Neural crest cell migration in cancer; 3q29 copy number variation syndrome; Pleural mesothelioma; Regulation of actin cytoskeleton; ErbB signaling pathway"	"Regulation of activated PAK-2p34 by proteasome mediated degradation; MAPK6/MAPK4 signaling; CDC42 GTPase cycle; RAC1 GTPase cycle; FCERI mediated MAPK activation; Generation of second messenger molecules; Regulation of PAK-2p34 activity by PS-GAP/RHG10; RHOQ GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOJ GTPase cycle; RHOV GTPase cycle; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; RHOU GTPase cycle; Ephrin signaling; Sema3A PAK dependent Axon repulsion; Smooth Muscle Contraction; RHO GTPases activate PAKs; VEGFR2 mediated vascular permeability; Activation of RAC1; RHOH GTPase cycle; CD209 (DC-SIGN) signaling; CD28 dependent Vav1 pathway; Nef and signal transduction; Stimulation of the cell death response by PAK-2p34"	"43"	"0"	"32.8"	"37.7"	"51.7"	"38.1"	"48.9"	"48.0"	"43.0"	"79.9"	"166.7"	"711.3"	"1800.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3Z3"	"Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 OS=Homo sapiens OX=9606 GN=SAMHD1 PE=1 SV=2"	"7"	"3"	"6"	"3"	"626"	"72.2"	"7.14"	"1269.19"	"11.54"	"3"	"3"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01966, Pf07647"	"25939"	"ENSG00000101347"	"SAMHD1"	"B4E2A5; E1P5V2; hsa:25939; Q5JXG8; Q8N491; Q9H004; Q9H005; Q9H3U9; Q9Y3Z3"	""	"Interferon alpha/beta signaling; Nucleotide catabolism"	"2"	"0"	"22.3"	"21.1"	"26.0"	"28.8"	"29.2"	"25.9"	"36.8"	"43.7"	"88.9"	"196.5"	"294.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NW82"	"WD repeat-containing protein 70 OS=Homo sapiens OX=9606 GN=WDR70 PE=1 SV=1"	"8"	"4"	"7"	"4"	"654"	"73.2"	"6.33"	"1508.23"	"11.53"	"4"	"3"	""	"nucleus;other cell component"	"other molecular function"	"Pf00400"	"55100"	"ENSG00000082068"	"WDR70"	"hsa:55100; Q9H053; Q9NW82"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"233.4"	"214.9"	"277.0"	"256.2"	"308.2"	"189.5"	"281.9"	"357.9"	"432.9"	"665.8"	"1051.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15910"	"Histone-lysine N-methyltransferase EZH2 OS=Homo sapiens OX=9606 GN=EZH2 PE=1 SV=2"	"6"	"4"	"7"	"4"	"746"	"85.3"	"7.02"	"1128.92"	"11.52"	"3"	"4"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00856, Pf11616, Pf18118, Pf18264"	"2146"	"ENSG00000106462"	"EZH2"	"B2RAQ1; B3KS30; B7Z1D6; B7Z7L6; hsa:2146; Q15755; Q15910; Q75MG3; Q92857; Q96FI6"	"Cell differentiation - expanded index; Histone modifications; Endoderm differentiation; Interactome of polycomb repressive complex 2 (PRC2) ; MECP2 and associated Rett syndrome; Tumor suppressor activity of SMARCB1; Epithelial to mesenchymal transition in colorectal cancer; lncRNA in canonical Wnt signaling and colorectal cancer; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; Pleural mesothelioma"	"HCMV Early Events; Defective pyroptosis; Oxidative Stress Induced Senescence; Activation of anterior HOX genes in hindbrain development during early embryogenesis; PRC2 methylates histones and DNA; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6; PKMTs methylate histone lysines"	"19"	"0"	"277.2"	"269.4"	"322.3"	"269.9"	"294.1"	"291.0"	"341.7"	"422.2"	"777.5"	"1857.4"	"2351.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P36957"	"Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLST PE=1 SV=4"	"6"	"3"	"6"	"3"	"453"	"48.7"	"8.95"	"1243.12"	"11.51"	"3"	"3"	"protein metabolism;other metabolic processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00198, Pf00364"	"1743"	"ENSG00000119689"	"DLST"	"B7Z5W8; E7ESY5; hsa:1743; P36957; Q7LDY7; Q9BQ32"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Metabolic reprogramming in colon cancer; 7q11.23 copy number variation syndrome; 1p36 copy number variation syndrome; 10q11.21q11.23 copy number variation syndrome; TCA cycle (aka Krebs or citric acid cycle)"	"Citric acid cycle (TCA cycle); Glyoxylate metabolism and glycine degradation; Lysine catabolism"	"10"	"0"	"464.1"	"351.9"	"471.4"	"436.8"	"459.3"	"484.6"	"524.4"	"556.0"	"804.4"	"1069.9"	"1308.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62266"	"40S ribosomal protein S23 OS=Homo sapiens OX=9606 GN=RPS23 PE=1 SV=3"	"32"	"3"	"5"	"3"	"143"	"15.8"	"10.49"	"747.93"	"11.50"	"2"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00164"	"6228"	"ENSG00000186468"	"RPS23"	"hsa:6228; P39028; P62266; Q6IB08"	"Cytoplasmic ribosomal proteins"	"GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"176.9"	"195.7"	"161.4"	"159.5"	"172.8"	"194.6"	"214.0"	"268.2"	"463.4"	"824.2"	"1233.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14573"	"Inositol 1,4,5-trisphosphate receptor type 3 OS=Homo sapiens OX=9606 GN=ITPR3 PE=1 SV=2"	"2"	"5"	"9"	"3"	"2671"	"303.9"	"6.48"	"1578.49"	"11.49"	"5"	"4"	"transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf00520, Pf01365, Pf02815, Pf08454, Pf08709"	"3710"	"ENSG00000096433"	"ITPR3"	"hsa:3710; Q14573; Q14649; Q5TAQ2"	"Alzheimer's disease and miRNA effects; Myometrial relaxation and contraction pathways; MFAP5-mediated ovarian cancer cell motility and invasiveness; GPR40 pathway; Vitamin D-sensitive calcium signaling in depression; Airway smooth muscle cell contraction; Pleural mesothelioma; Alzheimer's disease; GDNF signaling; Calcium regulation in cardiac cells"	"Ion homeostasis; Role of phospholipids in phagocytosis; FCERI mediated Ca+2 mobilization; FCGR3A-mediated IL10 synthesis; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Sensory perception of sweet, bitter, and umami (glutamate) taste; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Ca2+ pathway; VEGFR2 mediated cell proliferation; Elevation of cytosolic Ca2+ levels; PLC beta mediated events; DAG and IP3 signaling; CLEC7A (Dectin-1) induces NFAT activation; Effects of PIP2 hydrolysis"	"25"	"0"	"76.2"	"79.9"	"98.3"	"77.6"	"93.8"	"100.0"	"99.0"	"122.8"	"230.3"	"558.1"	"887.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75528"	"Transcriptional adapter 3 OS=Homo sapiens OX=9606 GN=TADA3 PE=1 SV=1"	"6"	"1"	"2"	"1"	"432"	"48.9"	"6.27"	""	"11.48"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf10198"	"10474"	"ENSG00000171148"	"TADA3"	"hsa:10474; O75528; Q6FI83; Q9UFS2"	""	"Ub-specific processing proteases; Formation of WDR5-containing histone-modifying complexes; HATs acetylate histones"	"3"	"0"	"44.9"	"42.6"	"59.2"	"43.7"	"45.1"	"43.5"	"55.2"	"69.6"	"156.3"	"235.0"	"237.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96Q89"	"Kinesin-like protein KIF20B OS=Homo sapiens OX=9606 GN=KIF20B PE=1 SV=3"	"2"	"3"	"6"	"3"	"1820"	"210.5"	"5.67"	"985.30"	"11.47"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225"	"9585"	"ENSG00000138182"	"KIF20B"	"A8MXM7; hsa:9585; O43277; Q09471; Q2KQ73; Q32NE1; Q561V3; Q58EX8; Q5T9M8; Q5T9M9; Q5T9N0; Q5T9N1; Q7KZ68; Q7Z5E0; Q7Z5E1; Q7Z6M9; Q86X82; Q96Q89; Q9H3R8; Q9H6Q9; Q9H755; Q9NTC1; Q9UFR5"	"Gastric cancer network 1"	"COPI-dependent Golgi-to-ER retrograde traffic; Kinesins"	"3"	"0"	"35.3"	"32.9"	"42.8"	"30.7"	"30.0"	"37.1"	"55.7"	"48.3"	"89.0"	"166.2"	"202.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14497"	"AT-rich interactive domain-containing protein 1A OS=Homo sapiens OX=9606 GN=ARID1A PE=1 SV=3"	"2"	"3"	"6"	"3"	"2285"	"241.9"	"6.70"	"1136.31"	"11.46"	"3"	"3"	"cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01388, Pf12031"	"8289"	"ENSG00000117713"	"ARID1A"	"D3DPL1; hsa:8289; O14497; Q53FK9; Q5T0W1; Q5T0W2; Q5T0W3; Q8NFD6; Q96T89; Q9BY33; Q9HBJ5; Q9UPZ1"	"Androgen receptor network in prostate cancer; Pathways affected in adenoid cystic carcinoma; Tumor suppressor activity of SMARCB1; Thermogenesis; Kleefstra syndrome"	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; RMTs methylate histone arginines"	"7"	"0"	"71.8"	"76.4"	"80.7"	"74.5"	"77.1"	"80.9"	"101.3"	"123.5"	"356.4"	"746.6"	"933.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NYB0"	"Telomeric repeat-binding factor 2-interacting protein 1 OS=Homo sapiens OX=9606 GN=TERF2IP PE=1 SV=1"	"9"	"3"	"8"	"3"	"399"	"44.2"	"4.73"	"1308.23"	"11.46"	"3"	"3"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf08914, Pf11626, Pf16589"	"54386"	"ENSG00000166848"	"TERF2IP"	"B4DQN4; hsa:54386; Q4W4Y2; Q8WYZ3; Q9NWR2; Q9NYB0"	"Splicing factor NOVA regulated synaptic proteins; SARS-CoV-2 mitochondrial chronic oxidative stress and endothelial dysfunction"	"DNA Damage/Telomere Stress Induced Senescence; Meiotic synapsis; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; Packaging Of Telomere Ends; Polymerase switching on the C-strand of the telomere; Removal of the Flap Intermediate from the C-strand; Telomere Extension By Telomerase; Telomere C-strand synthesis initiation"	"16"	"0"	"147.4"	"118.4"	"147.8"	"127.9"	"137.5"	"166.8"	"190.2"	"185.0"	"233.4"	"409.8"	"583.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00399"	"Dynactin subunit 6 OS=Homo sapiens OX=9606 GN=DCTN6 PE=1 SV=1"	"9"	"1"	"4"	"1"	"190"	"20.7"	"6.32"	"1105.74"	"11.44"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	""	"10671"	"ENSG00000104671"	"DCTN6"	"B2RAC1; hsa:10671; O00399"	""	"MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic"	"4"	"0"	"41.3"	"36.8"	"52.5"	"47.9"	"47.3"	"46.9"	"55.3"	"93.5"	"260.9"	"595.9"	"994.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q68CQ4"	"Digestive organ expansion factor homolog OS=Homo sapiens OX=9606 GN=DIEXF PE=1 SV=2"	"5"	"4"	"8"	"4"	"756"	"87.0"	"5.88"	"1218.03"	"11.44"	"4"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf06862"	"27042"	"ENSG00000117597"	"UTP25"	"hsa:27042; O75992; Q4VY00; Q63HL9; Q68CQ4"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"215.8"	"198.6"	"217.9"	"214.6"	"222.2"	"242.9"	"265.2"	"264.9"	"286.2"	"394.5"	"622.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y6M1"	"Insulin-like growth factor 2 mRNA-binding protein 2 OS=Homo sapiens OX=9606 GN=IGF2BP2 PE=1 SV=2"	"6"	"3"	"6"	"1"	"599"	"66.1"	"8.46"	"1108.87"	"11.42"	"3"	"3"	"other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf00076"	"10644"	"ENSG00000073792"	"IGF2BP2"	"A0A4Z0; B3FTN2; B3FTN3; B3FTN4; hsa:10644; Q9Y6M1"	""	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"	"1"	"0"	"70.2"	"78.0"	"72.8"	"68.0"	"72.8"	"69.5"	"81.0"	"96.1"	"142.7"	"232.1"	"310.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H7N4"	"Splicing factor, arginine/serine-rich 19 OS=Homo sapiens OX=9606 GN=SCAF1 PE=1 SV=3"	"4"	"4"	"7"	"3"	"1312"	"139.2"	"9.25"	"1367.55"	"11.40"	"4"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	""	"58506"	"ENSG00000126461"	"SCAF1"	"hsa:58506; Q7Z5V7; Q8WVA1; Q9H7N4; Q9NR59"	""	""	"0"	"0"	"234.7"	"231.1"	"264.0"	"204.2"	"250.0"	"240.5"	"293.6"	"362.4"	"466.8"	"746.9"	"1136.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14744"	"Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4"	"8"	"3"	"5"	"3"	"637"	"72.6"	"6.29"	"605.65"	"11.40"	"2"	"3"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05185, Pf17285, Pf17286"	"10419"	"ENSG00000100462"	"PRMT5"	"A8MTP3; A8MZ91; B4DX49; B4DY30; B5BU10; D3DS33; E2QRE7; hsa:10419; O14744; Q6IBR1; Q9UKH1"	"Transcription co-factors SKI and SKIL protein partners; Nitric oxide metabolism in cystic fibrosis"	"snRNP Assembly; RMTs methylate histone arginines; Regulation of TP53 Activity through Methylation"	"5"	"0"	"68.2"	"51.1"	"68.7"	"61.7"	"67.4"	"71.2"	"82.2"	"98.3"	"184.8"	"397.3"	"603.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BZI7"	"Regulator of nonsense transcripts 3B OS=Homo sapiens OX=9606 GN=UPF3B PE=1 SV=1"	"11"	"4"	"7"	"4"	"483"	"57.7"	"9.48"	"1956.01"	"11.39"	"4"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity"	"Pf03467"	"65109"	"ENSG00000125351"	"UPF3B"	"D3DWI3; D3DWI4; hsa:65109; Q0VAK8; Q9BZI7; Q9H1J0"	""	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway"	"6"	"0"	"581.5"	"462.6"	"514.0"	"446.0"	"527.9"	"544.9"	"648.7"	"621.2"	"772.1"	"955.8"	"1171.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92522"	"Histone H1.10 OS=Homo sapiens OX=9606 GN=H1-10 PE=1 SV=1"	"13"	"3"	"6"	"3"	"213"	"22.5"	"10.76"	"1285.68"	"11.38"	"3"	"3"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00538"	"8971"	"ENSG00000184897"	"H1-10"	"hsa:8971; Q92522"	""	""	"0"	"0"	"219.7"	"209.0"	"221.6"	"194.6"	"224.2"	"224.4"	"268.0"	"281.3"	"399.1"	"634.8"	"959.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H5V9"	"UPF0428 protein CXorf56 OS=Homo sapiens OX=9606 GN=CXorf56 PE=1 SV=1"	"17"	"4"	"8"	"4"	"222"	"25.6"	"8.73"	"1226.84"	"11.34"	"4"	"4"	"cell organization and biogenesis;transport"	"cytoskeleton;nucleus;other cell component"	""	""	"63932"	"ENSG00000018610"	"STEEP1"	"A8MPX7; B4DQN2; D3DWH9; F5GWL7; hsa:63932; O43351; Q9H5V9"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"643.9"	"508.5"	"652.2"	"591.5"	"594.7"	"565.1"	"711.1"	"802.2"	"1225.3"	"2142.1"	"2484.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H9B1"	"Histone-lysine N-methyltransferase EHMT1 OS=Homo sapiens OX=9606 GN=EHMT1 PE=1 SV=4"	"4"	"4"	"7"	"4"	"1298"	"141.4"	"5.76"	"1424.97"	"11.33"	"4"	"3"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00856, Pf05033, Pf12796"	"79813"	"ENSG00000181090"	"EHMT1"	"B1AQ58; B1AQ59; hsa:79813; Q86X08; Q8TCN7; Q96F53; Q96JF1; Q96KH4; Q9H9B1"	"Histone modifications; MTHFR deficiency; Kleefstra syndrome"	"Senescence-Associated Secretory Phenotype (SASP); Regulation of TP53 Activity through Methylation; Transcriptional Regulation by E2F6; Transcriptional Regulation by VENTX; PKMTs methylate histone lysines"	"8"	"0"	"235.5"	"213.4"	"248.4"	"204.0"	"228.9"	"212.1"	"279.5"	"315.3"	"486.2"	"839.7"	"1257.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9GZT3"	"SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1"	"33"	"3"	"6"	"3"	"109"	"12.3"	"10.24"	"1036.54"	"11.30"	"3"	"3"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;mitochondrion;nucleus;other cell component"	""	"Pf00076"	"81892"	"ENSG00000119705"	"SLIRP"	"hsa:81892; J3KMY7; Q9GZT3"	""	""	"0"	"0"	"148.6"	"143.0"	"192.1"	"173.9"	"177.7"	"179.2"	"199.3"	"269.1"	"471.3"	"830.6"	"1086.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46783"	"40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1"	"37"	"6"	"13"	"5"	"165"	"18.9"	"10.15"	"3799.77"	"11.28"	"6"	"4"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf03501"	"6204"	"ENSG00000124614"	"RPS10"	"B2R4E3; hsa:6204; P46783; Q5TZC0"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"1268.8"	"1556.8"	"1252.2"	"1083.9"	"1235.6"	"1198.2"	"1456.9"	"1415.0"	"1730.7"	"2141.8"	"2573.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IUH3"	"RNA-binding protein 45 OS=Homo sapiens OX=9606 GN=RBM45 PE=1 SV=1"	"8"	"4"	"8"	"4"	"476"	"53.5"	"7.17"	"1336.29"	"11.27"	"4"	"4"	"developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"129831"	"ENSG00000155636"	"RBM45"	"hsa:129831; Q6NYL0; Q8IUH3; Q8NFC9"	""	""	"0"	"0"	"577.8"	"555.2"	"585.9"	"496.6"	"575.2"	"578.3"	"666.4"	"761.2"	"939.8"	"1378.6"	"2018.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IUD2"	"ELKS/Rab6-interacting/CAST family member 1 OS=Homo sapiens OX=9606 GN=ERC1 PE=1 SV=1"	"4"	"4"	"7"	"4"	"1116"	"128.0"	"5.97"	"1601.83"	"11.23"	"4"	"3"	"cell-cell signaling;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf09457, Pf10174"	"23085"	"ENSG00000082805"	"ERC1"	"A2RU77; A7E295; D3DUP7; D3DUP8; hsa:23085; Q6NVK2; Q8IUD2; Q8IUD3; Q8IUD4; Q8IUD5; Q8NAS1; Q9NXN5; Q9UIK7; Q9UPS1"	""	""	"0"	"0"	"135.9"	"123.7"	"177.0"	"135.0"	"171.2"	"172.3"	"171.3"	"202.2"	"477.3"	"964.7"	"1402.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60884"	"DnaJ homolog subfamily A member 2 OS=Homo sapiens OX=9606 GN=DNAJA2 PE=1 SV=1"	"9"	"3"	"6"	"3"	"412"	"45.7"	"6.48"	"983.98"	"11.22"	"3"	"3"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;other cell component"	"other molecular function"	"Pf00226, Pf00684, Pf01556"	"10294"	"ENSG00000069345"	"DNAJA2"	"B2R7L7; hsa:10294; O14711; O60884"	""	"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand"	"1"	"0"	"134.0"	"148.8"	"117.4"	"124.6"	"138.8"	"134.8"	"146.4"	"129.1"	"149.2"	"268.1"	"374.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75955"	"Flotillin-1 OS=Homo sapiens OX=9606 GN=FLOT1 PE=1 SV=3"	"11"	"3"	"6"	"3"	"427"	"47.3"	"7.49"	"1482.94"	"11.21"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01145"	"10211"	"ENSG00000137312; ENSG00000206379; ENSG00000206480; ENSG00000230143; ENSG00000232280"	"FLOT1"	"B4DVY7; hsa:10211; O75955; Q969J8; Q9UHW1; Q9UNV8"	"Angiopoietin-like protein 8 regulatory pathway; Insulin signaling"	"RHOC GTPase cycle; RHOA GTPase cycle; RHOB GTPase cycle; Regulation of necroptotic cell death; Synaptic adhesion-like molecules"	"8"	"0"	"52.4"	"60.0"	"63.2"	"51.1"	"65.7"	"62.2"	"64.9"	"91.9"	"170.5"	"282.4"	"399.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01844"	"RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1"	"6"	"3"	"5"	"3"	"656"	"68.4"	"9.33"	"702.97"	"11.19"	"2"	"3"	"other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00076, Pf00641"	"2130"	"ENSG00000182944"	"EWSR1"	"B0QYK1; hsa:2130; Q01844; Q5THL0; Q92635; Q96FE8; Q96MN4; Q96MX4; Q9BWA2"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"310.9"	"358.3"	"316.9"	"270.5"	"290.7"	"313.8"	"381.1"	"441.4"	"629.5"	"896.6"	"1139.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22392"	"Nucleoside diphosphate kinase B OS=Homo sapiens OX=9606 GN=NME2 PE=1 SV=1"	"24"	"3"	"6"	"3"	"152"	"17.3"	"8.41"	"1253.42"	"11.17"	"3"	"3"	"cell adhesion;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00334"	"4831; 654364"	"ENSG00000243678"	"NME2"	"A8MWA3; hsa:4831; hsa:654364; P22392; Q1WM23; Q6LCT6"	"Pyrimidine metabolism"	"Neutrophil degranulation; Interconversion of nucleotide di- and triphosphates; Azathioprine ADME; Ribavirin ADME"	"5"	"0"	"133.3"	"170.3"	"189.5"	"158.0"	"162.4"	"151.8"	"186.1"	"282.7"	"523.3"	"952.2"	"1415.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P29144"	"Tripeptidyl-peptidase 2 OS=Homo sapiens OX=9606 GN=TPP2 PE=1 SV=4"	"4"	"4"	"6"	"4"	"1249"	"138.3"	"6.32"	"1076.04"	"11.16"	"3"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00082, Pf12580"	"7174"	"ENSG00000134900"	"TPP2"	"hsa:7174; P29144; Q5VZU8"	""	"Antigen processing: Ubiquitination & Proteasome degradation"	"1"	"0"	"69.6"	"62.8"	"59.8"	"49.5"	"58.1"	"59.0"	"85.1"	"90.0"	"208.0"	"495.3"	"966.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15182"	"Centrin-3 OS=Homo sapiens OX=9606 GN=CETN3 PE=1 SV=2"	"27"	"2"	"3"	"2"	"167"	"19.5"	"4.74"	"540.61"	"11.16"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf13499"	"1070"	"ENSG00000153140"	"CETN3"	"hsa:1070; O15182; Q53YD2; Q9BS23"	"Breast cancer pathway"	""	"1"	"0"	"23.5"	"25.1"	"31.2"	"30.9"	"33.8"	"31.2"	"56.6"	"101.3"	"221.8"	"332.3"	"422.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBD5"	"Origin recognition complex subunit 3 OS=Homo sapiens OX=9606 GN=ORC3 PE=1 SV=1"	"5"	"3"	"6"	"3"	"711"	"82.2"	"7.61"	"1185.80"	"11.14"	"3"	"3"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf07034, Pf18137, Pf19675"	"23595"	"ENSG00000135336"	"ORC3"	"A2A2T5; B4E025; hsa:23595; Q13565; Q53GY6; Q5T159; Q6IUY7; Q86TN5; Q9UBD5; Q9UG44; Q9UNT6"	"Cell cycle; G1 to S cell cycle control; DNA replication"	"Assembly of the ORC complex at the origin of replication; Orc1 removal from chromatin; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; E2F-enabled inhibition of pre-replication complex formation; CDC6 association with the ORC:origin complex"	"10"	"0"	"92.7"	"103.4"	"108.5"	"94.2"	"99.5"	"106.8"	"122.4"	"157.3"	"355.8"	"899.3"	"1239.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H4G4"	"Golgi-associated plant pathogenesis-related protein 1 OS=Homo sapiens OX=9606 GN=GLIPR2 PE=1 SV=3"	"17"	"2"	"6"	"2"	"154"	"17.2"	"9.41"	"1464.64"	"11.13"	"2"	"2"	"other biological processes"	"non-structural extracellular;other membranes;ER/Golgi"	"other molecular function"	"Pf00188"	"152007"	"ENSG00000122694"	"GLIPR2"	"hsa:152007; Q5VZR1; Q8N2S6; Q8WWC9; Q8WX36; Q9H4G4"	""	""	"0"	"0"	"242.8"	"238.8"	"224.9"	"206.5"	"239.7"	"251.9"	"304.6"	"379.2"	"531.1"	"800.9"	"1059.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99575"	"Ribonucleases P/MRP protein subunit POP1 OS=Homo sapiens OX=9606 GN=POP1 PE=1 SV=2"	"4"	"3"	"5"	"3"	"1024"	"114.6"	"9.22"	"261.83"	"11.11"	"1"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06978, Pf08170"	"10940"	"ENSG00000104356"	"POP1"	"A8K5W9; hsa:10940; Q15037; Q99575"	""	"tRNA processing in the nucleus"	"1"	"0"	"443.2"	"106.9"	"756.0"	"521.8"	"514.0"	"551.6"	"521.4"	"401.3"	"697.7"	"670.0"	"1158.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IY63"	"Angiomotin-like protein 1 OS=Homo sapiens OX=9606 GN=AMOTL1 PE=1 SV=1"	"4"	"4"	"8"	"1"	"956"	"106.5"	"7.11"	"1092.31"	"11.09"	"4"	"4"	"cell-cell signaling;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf12240"	"154810"	"ENSG00000166025"	"AMOTL1"	"hsa:154810; Q63HK7; Q8IY63; Q8NDN0; Q8TEN8; Q8WXD1; Q96CM5"	""	"Signaling by Hippo"	"1"	"0"	"49.3"	"41.6"	"50.3"	"47.0"	"40.9"	"46.0"	"48.1"	"61.6"	"69.2"	"105.9"	"139.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H2P0"	"Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1"	"3"	"3"	"5"	"3"	"1102"	"123.5"	"7.34"	"896.72"	"11.09"	"2"	"3"	"cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00046, Pf19627"	"23394"	"ENSG00000101126"	"ADNP"	"E1P5Y2; hsa:23394; O94881; Q5BKU2; Q9H2P0; Q9UG34"	""	""	"0"	"0"	"311.7"	"292.5"	"340.5"	"287.9"	"320.5"	"304.7"	"360.4"	"443.0"	"610.9"	"1072.0"	"1912.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q02809"	"Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 OS=Homo sapiens OX=9606 GN=PLOD1 PE=1 SV=2"	"6"	"3"	"6"	"3"	"727"	"83.5"	"6.95"	"1051.19"	"11.08"	"3"	"3"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf03171"	"5351"	"ENSG00000083444"	"PLOD1"	"B4DR87; hsa:5351; Q02809; Q96AV9; Q9H132"	"Type I collagen synthesis in the context of osteogenesis imperfecta"	"Collagen biosynthesis and modifying enzymes"	"2"	"0"	"97.0"	"96.6"	"123.1"	"108.3"	"112.9"	"100.8"	"128.4"	"170.0"	"331.2"	"668.3"	"900.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19793"	"Retinoic acid receptor RXR-alpha OS=Homo sapiens OX=9606 GN=RXRA PE=1 SV=1"	"7"	"2"	"3"	"2"	"462"	"50.8"	"7.80"	""	"11.07"	""	"2"	"RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00104, Pf00105, Pf11825"	"6256"	"ENSG00000186350"	"RXRA"	"B3KY83; hsa:6256; P19793; Q2NL52; Q2V504"	"Vitamin D metabolism; Energy metabolism; Nuclear receptors; Adipogenesis; Liver X receptor pathway; Constitutive androstane receptor pathway; Pregnane X receptor pathway; Vitamin D receptor pathway; PPAR-alpha pathway; Farnesoid X receptor pathway; Glucocorticoid receptor pathway; Nuclear receptors meta-pathway; NRF2 pathway; Transcription factor regulation in adipogenesis; Angiopoietin-like protein 8 regulatory pathway; PPAR signaling pathway; Prion disease pathway; PI3K/AKT/mTOR - vitamin D3 signaling; Non-small cell lung cancer; Non-genomic actions of 1,25 dihydroxyvitamin D3; Vitamins A and D - action mechanisms; Nonalcoholic fatty liver disease; Vitamin D in inflammatory diseases; Small cell lung cancer; Vitamin D-sensitive calcium signaling in depression; Thyroid hormones production and peripheral downstream signaling effects; Antiviral and anti-inflammatory effects of Nrf2 on SARS-CoV-2 pathway; Th17 cell differentiation pathway; Kleefstra syndrome; Vitamin A1 and A5/X pathways; Vitamin A and carotenoid metabolism"	"Activation of anterior HOX genes in hindbrain development during early embryogenesis; NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux; Transcriptional activation of mitochondrial biogenesis; Cytoprotection by HMOX1; PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; Endogenous sterols; Heme signaling; BMAL1:CLOCK,NPAS2 activates circadian gene expression; Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid; Nuclear Receptor transcription pathway; SUMOylation of intracellular receptors; Carnitine metabolism; Activation of gene expression by SREBF (SREBP); NR1H2 & NR1H3 regulate gene expression linked to lipogenesis; Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol; Recycling of bile acids and salts; NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose; Transcriptional regulation of granulopoiesis; RORA activates gene expression; NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis; Synthesis of bile acids and bile salts via 27-hydroxycholesterol; NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake ; NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis"	"59"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99700"	"Ataxin-2 OS=Homo sapiens OX=9606 GN=ATXN2 PE=1 SV=2"	"2"	"2"	"4"	"2"	"1313"	"140.2"	"9.57"	"990.52"	"11.07"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity"	"Pf06741, Pf07145, Pf14438"	"6311"	"ENSG00000204842"	"ATXN2"	"A6NLD4; hsa:6311; Q24JQ7; Q6ZQZ7; Q99493; Q99700"	"Parkinson's disease pathway; EGF/EGFR signaling pathway"	""	"2"	"0"	"103.0"	"80.6"	"103.5"	"97.8"	"113.2"	"88.0"	"121.1"	"122.8"	"166.5"	"354.9"	"494.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95793"	"Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2"	"6"	"3"	"6"	"3"	"577"	"63.1"	"9.44"	"981.56"	"11.07"	"3"	"3"	"cell organization and biogenesis;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00035, Pf16482"	"6780"	"ENSG00000124214"	"STAU1"	"A8K9Z4; E1P5Y1; E1P608; hsa:6780; O95793; Q5JW29; Q6GTM4; Q9H5B4; Q9H5B5; Q9Y3Q2"	""	""	"0"	"0"	"61.8"	"52.4"	"83.4"	"75.9"	"76.6"	"79.8"	"90.8"	"100.7"	"155.4"	"347.8"	"568.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19022"	"Cadherin-2 OS=Homo sapiens OX=9606 GN=CDH2 PE=1 SV=4"	"4"	"4"	"6"	"4"	"906"	"99.7"	"4.81"	"1049.53"	"10.99"	"3"	"3"	"cell adhesion;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00028, Pf01049, Pf08758"	"1000"	"ENSG00000170558"	"CDH2"	"A8MWK3; B0YIY6; hsa:1000; P19022; Q14923; Q8N173"	"Neural crest differentiation; Arrhythmogenic right ventricular cardiomyopathy; Brain-derived neurotrophic factor (BDNF) signaling pathway; Primary focal segmental glomerulosclerosis (FSGS); Splicing factor NOVA regulated synaptic proteins; Epithelial to mesenchymal transition in colorectal cancer; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; Pleural mesothelioma; CCL18 signaling pathway; GDNF signaling; A network map of Macrophage-stimulating protein (MSP) signaling"	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Myogenesis; Adherens junctions interactions"	"16"	"0"	"171.4"	"155.0"	"205.0"	"192.2"	"211.1"	"202.3"	"230.2"	"251.6"	"467.9"	"805.8"	"1142.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P42677"	"40S ribosomal protein S27 OS=Homo sapiens OX=9606 GN=RPS27 PE=1 SV=3"	"26"	"3"	"6"	"3"	"84"	"9.5"	"9.45"	"1007.60"	"10.97"	"3"	"3"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01667"	"6232"	"ENSG00000177954"	"RPS27"	"hsa:6232; P42677; Q5T4L6"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"25"	"0"	"176.4"	"185.7"	"192.0"	"174.9"	"176.0"	"153.8"	"218.8"	"277.2"	"440.3"	"824.8"	"1125.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15446"	"DNA-directed RNA polymerase I subunit RPA34 OS=Homo sapiens OX=9606 GN=CD3EAP PE=1 SV=1"	"12"	"3"	"5"	"3"	"510"	"55.0"	"8.51"	"983.29"	"10.95"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes;signal transduction"	"cytosol;mitochondrion;nucleus;other cell component"	""	"Pf08208"	"10849"	"ENSG00000117877"	"POLR1G"	"hsa:10849; O15446; Q32N11; Q7Z5U2; Q9UPF6"	"2q13 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"6"	"0"	"61.0"	"40.8"	"68.4"	"65.6"	"69.2"	"55.5"	"97.7"	"153.6"	"295.2"	"384.7"	"456.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00116"	"Alkyldihydroxyacetonephosphate synthase, peroxisomal OS=Homo sapiens OX=9606 GN=AGPS PE=1 SV=1"	"7"	"3"	"5"	"3"	"658"	"72.9"	"7.34"	"950.43"	"10.93"	"2"	"3"	"other metabolic processes"	"cytosol;other cytoplasmic organelle"	"other molecular function"	"Pf01565, Pf02913"	"8540"	"ENSG00000018510"	"AGPS"	"A5D8U9; hsa:8540; O00116; Q2TU35"	"Triacylglyceride synthesis"	"Plasmalogen biosynthesis; TYSND1 cleaves peroxisomal proteins"	"4"	"0"	"126.0"	"119.2"	"134.6"	"110.8"	"139.0"	"104.4"	"148.0"	"178.2"	"293.9"	"394.7"	"448.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NVH1"	"DnaJ homolog subfamily C member 11 OS=Homo sapiens OX=9606 GN=DNAJC11 PE=1 SV=2"	"8"	"3"	"6"	"3"	"559"	"63.2"	"8.40"	"1257.93"	"10.93"	"3"	"3"	"cell organization and biogenesis"	"other membranes;mitochondrion;nucleus"	""	"Pf00226, Pf11875"	"55735"	"ENSG00000007923"	"DNAJC11"	"hsa:55735; Q4VWF5; Q5VZN0; Q6PK20; Q6PK70; Q8NDM2; Q96CL7; Q9NVH1"	""	"Cristae formation"	"1"	"0"	"36.9"	"37.5"	"47.1"	"35.9"	"44.6"	"34.7"	"39.1"	"67.1"	"125.4"	"204.1"	"275.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NFH5"	"Nucleoporin NUP35 OS=Homo sapiens OX=9606 GN=NUP35 PE=1 SV=1"	"16"	"4"	"7"	"4"	"326"	"34.8"	"9.09"	"1599.64"	"10.93"	"4"	"3"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf05172"	"129401"	"ENSG00000163002"	"NUP35"	"B4DP57; B4DYB4; hsa:129401; Q4ZFZ9; Q53S95; Q8NFH5; Q8TDJ1"	""	"ISG15 antiviral mechanism; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; SUMOylation of DNA damage response and repair proteins; Transport of Mature mRNA derived from an Intron-Containing Transcript; HCMV Early Events; HCMV Late Events; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; Postmitotic nuclear pore complex (NPC) reformation"	"29"	"0"	"462.3"	"403.4"	"425.9"	"361.4"	"439.4"	"430.5"	"508.8"	"546.3"	"700.9"	"1267.0"	"1823.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P16615"	"Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2A2 PE=1 SV=1"	"4"	"3"	"6"	"3"	"1042"	"114.7"	"5.34"	"1079.37"	"10.92"	"3"	"3"	"cell adhesion;cell organization and biogenesis;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"transporter activity;other molecular function"	"Pf00122, Pf00689, Pf00690, Pf08282, Pf13246"	"488"	"ENSG00000174437"	"ATP2A2"	"A6NDN7; B4DF05; hsa:488; P16614; P16615; Q86VJ2"	"Alzheimer's disease and miRNA effects; Arrhythmogenic right ventricular cardiomyopathy; Endothelin pathways; Myometrial relaxation and contraction pathways; Alzheimer's disease; Calcium regulation in cardiac cells"	"Ion homeostasis; Ion transport by P-type ATPases; Pre-NOTCH Processing in Golgi; Reduction of cytosolic Ca++ levels"	"10"	"0"	"155.1"	"160.0"	"193.6"	"184.8"	"210.7"	"187.5"	"214.8"	"250.2"	"530.9"	"910.4"	"1190.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75592"	"E3 ubiquitin-protein ligase MYCBP2 OS=Homo sapiens OX=9606 GN=MYCBP2 PE=1 SV=4"	"1"	"4"	"8"	"4"	"4678"	"513.3"	"7.02"	"1169.65"	"10.90"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00415, Pf03256, Pf08005, Pf08239, Pf13540, Pf13639"	"23077"	"ENSG00000005810"	"MYCBP2"	"A6NJC6; hsa:23077; O75592; Q5JSX8; Q5VZN6; Q6PIB6; Q9UQ11; Q9Y6E4"	"3q29 copy number variation syndrome"	""	"1"	"0"	"257.8"	"254.6"	"275.2"	"237.3"	"278.4"	"257.5"	"345.2"	"445.9"	"705.9"	"1190.9"	"1667.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BVC5"	"Ashwin OS=Homo sapiens OX=9606 GN=C2orf49 PE=1 SV=1"	"18"	"2"	"3"	"2"	"232"	"25.8"	"9.74"	"565.74"	"10.88"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes;developmental processes"	"nucleus;other cell component"	""	"Pf15323"	"79074"	"ENSG00000135974"	"C2orf49"	"B3KXN3; B4E2G9; hsa:79074; Q9BVC5"	""	"tRNA processing in the nucleus"	"1"	"0"	"87.7"	"84.8"	"95.9"	"100.2"	"90.6"	"108.6"	"102.2"	"128.0"	"179.0"	"294.8"	"408.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y6W5"	"Wiskott-Aldrich syndrome protein family member 2 OS=Homo sapiens OX=9606 GN=WASF2 PE=1 SV=3"	"5"	"2"	"6"	"1"	"498"	"54.3"	"5.53"	"1327.01"	"10.86"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02205"	"10163"	"ENSG00000158195"	"WASF2"	"B4DZN0; hsa:10163; O60794; Q9UDY7; Q9Y6W5"	"Regulation of actin cytoskeleton"	"Regulation of actin dynamics for phagocytic cup formation; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; VEGFA-VEGFR2 Pathway"	"8"	"0"	"5.3"	"4.0"	"3.9"	"8.3"	"7.8"	"5.6"	"7.4"	"10.2"	"22.5"	"38.9"	"45.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WU90"	"Zinc finger CCCH domain-containing protein 15 OS=Homo sapiens OX=9606 GN=ZC3H15 PE=1 SV=1"	"10"	"4"	"7"	"4"	"426"	"48.6"	"5.31"	"1525.91"	"10.86"	"4"	"3"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00642, Pf16543"	"55854"	"ENSG00000065548"	"ZC3H15"	"B4DMW2; D3DPG7; hsa:55854; Q5QTQ4; Q8WU90; Q8WZ06; Q9NUZ3; Q9NZ37; Q9P079"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"516.6"	"482.1"	"529.6"	"404.2"	"488.9"	"396.2"	"594.8"	"673.0"	"914.5"	"1572.0"	"1637.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25787"	"Proteasome subunit alpha type-2 OS=Homo sapiens OX=9606 GN=PSMA2 PE=1 SV=2"	"16"	"3"	"6"	"3"	"234"	"25.9"	"7.43"	"1026.00"	"10.85"	"3"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	""	"Pf00227, Pf10584"	"5683"	"ENSG00000106588"	"PSMA2"	"hsa:5683; P25787; Q6ICS6; Q9BU45"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Ub-specific processing proteases; Antigen processing: Ubiquitination & Proteasome degradation; CDK-mediated phosphorylation and removal of Cdc6; SCF(Skp2)-mediated degradation of p27/p21; FCERI mediated NF-kB activation; Downstream TCR signaling; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Orc1 removal from chromatin; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"63"	"0"	"71.9"	"76.4"	"88.9"	"82.2"	"91.0"	"78.8"	"106.4"	"161.5"	"217.9"	"395.1"	"922.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P10599"	"Thioredoxin OS=Homo sapiens OX=9606 GN=TXN PE=1 SV=3"	"31"	"3"	"6"	"3"	"105"	"11.7"	"4.92"	"1122.99"	"10.82"	"3"	"3"	"other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00085"	"7295"	"ENSG00000136810"	"TXN"	"B1ALW1; hsa:7295; O60744; P10599; Q53X69; Q96KI3; Q9UDG5"	"Selenium micronutrient network; Folic acid network; Selenium micronutrient network ; Folic acid network; Selenium micronutrient network; TNF-alpha signaling pathway; Complement system; Nuclear receptors meta-pathway; NRF2 pathway; VEGFA-VEGFR2 signaling; TAR syndrome"	"Detoxification of Reactive Oxygen Species; Oxidative Stress Induced Senescence; TP53 Regulates Metabolic Genes; Interconversion of nucleotide di- and triphosphates; The NLRP3 inflammasome; Purinergic signaling in leishmaniasis infection; Regulation of FOXO transcriptional activity by acetylation; Protein repair"	"19"	"0"	"307.8"	"320.4"	"348.8"	"318.6"	"342.5"	"267.1"	"344.9"	"471.6"	"571.5"	"864.1"	"1149.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y608"	"Leucine-rich repeat flightless-interacting protein 2 OS=Homo sapiens OX=9606 GN=LRRFIP2 PE=1 SV=1"	"4"	"2"	"4"	"2"	"721"	"82.1"	"6.95"	"1008.84"	"10.77"	"2"	"2"	"cell-cell signaling;signal transduction;other biological processes"	""	"other molecular function"	"Pf09738"	"9209"	"ENSG00000093167"	"LRRFIP2"	"A8K649; A8MXR0; B4DY63; hsa:9209; Q68CV3; Q9NXH5; Q9Y608"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"15.1"	"14.8"	"14.5"	"18.4"	"15.7"	"11.6"	"23.7"	"27.6"	"102.5"	"278.8"	"600.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94905"	"Erlin-2 OS=Homo sapiens OX=9606 GN=ERLIN2 PE=1 SV=1"	"12"	"4"	"7"	"4"	"339"	"37.8"	"5.62"	"1634.77"	"10.76"	"4"	"3"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf01145"	"11160"	"ENSG00000147475"	"ERLIN2"	"A0JLQ1; A8K5S9; B4DM38; D3DSW0; hsa:11160; O94905; Q6NW21; Q86VS6; Q86W49"	""	"ABC-family proteins mediated transport; Defective CFTR causes cystic fibrosis; Signaling by FGFR1 in disease; Signaling by plasma membrane FGFR1 fusions"	"4"	"0"	"352.0"	"375.5"	"355.1"	"300.4"	"357.0"	"387.5"	"472.3"	"595.2"	"1034.2"	"2282.3"	"3438.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00487"	"26S proteasome non-ATPase regulatory subunit 14 OS=Homo sapiens OX=9606 GN=PSMD14 PE=1 SV=1"	"17"	"3"	"4"	"3"	"310"	"34.6"	"6.52"	"316.34"	"10.74"	"1"	"3"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf01398, Pf13012"	"10213"	"ENSG00000115233"	"PSMD14"	"B3KNW2; hsa:10213; O00176; O00487"	"Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Metalloprotease DUBs"	"64"	"0"	"102.7"	"100.3"	"111.4"	"98.7"	"113.2"	"121.3"	"123.2"	"141.5"	"201.7"	"635.0"	"1432.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07919"	"Cytochrome b-c1 complex subunit 6, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRH PE=1 SV=2"	"71"	"4"	"5"	"4"	"91"	"10.7"	"4.44"	"1064.46"	"10.70"	"3"	"2"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf02320"	"7388"	"ENSG00000173660"	"UQCRH"	"B2R4V9; D3DQ18; hsa:7388; P07919; Q5TDF6; Q6LDB8; Q9BQ91"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex III assembly"	"Respiratory electron transport"	"4"	"0"	"423.3"	"308.9"	"359.3"	"317.2"	"374.8"	"272.0"	"377.3"	"454.7"	"631.6"	"968.9"	"1256.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16698"	"2,4-dienoyl-CoA reductase, mitochondrial OS=Homo sapiens OX=9606 GN=DECR1 PE=1 SV=1"	"10"	"3"	"5"	"3"	"335"	"36.0"	"9.28"	"1031.39"	"10.70"	"2"	"3"	"other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf13561"	"1666"	"ENSG00000104325"	"DECR1"	"B7Z6B8; hsa:1666; Q16698; Q2M304; Q93085"	"Fatty acid beta-oxidation; Fatty acid biosynthesis; VEGFA-VEGFR2 signaling"	"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids"	"4"	"0"	"132.2"	"142.0"	"173.5"	"146.4"	"190.6"	"190.5"	"245.4"	"299.7"	"768.2"	"1196.1"	"1862.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q2NKX8"	"DNA excision repair protein ERCC-6-like OS=Homo sapiens OX=9606 GN=ERCC6L PE=1 SV=1"	"3"	"3"	"6"	"3"	"1250"	"141.0"	"5.31"	"924.04"	"10.68"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271"	"54821"	"ENSG00000186871"	"ERCC6L"	"hsa:54821; Q2NKX8; Q8NCI1; Q96H93; Q9NXQ8"	""	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"6"	"0"	"78.5"	"66.8"	"95.8"	"87.6"	"96.8"	"83.5"	"95.4"	"121.5"	"233.1"	"445.6"	"654.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96D46"	"60S ribosomal export protein NMD3 OS=Homo sapiens OX=9606 GN=NMD3 PE=1 SV=1"	"6"	"3"	"5"	"3"	"503"	"57.6"	"7.14"	"806.40"	"10.62"	"2"	"3"	"transport;other biological processes"	"nucleus;other cell component"	"translation activity;other molecular function"	"Pf04981"	"51068"	"ENSG00000169251"	"NMD3"	"D3DNM7; hsa:51068; Q96D46; Q9Y2Z6"	""	""	"0"	"0"	"80.3"	"82.1"	"87.7"	"85.5"	"97.4"	"103.6"	"106.5"	"121.6"	"378.7"	"1334.8"	"1943.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14C86"	"GTPase-activating protein and VPS9 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=GAPVD1 PE=1 SV=2"	"3"	"3"	"6"	"3"	"1478"	"164.9"	"5.22"	"819.53"	"10.61"	"3"	"3"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00616, Pf02204, Pf18151"	"26130"	"ENSG00000165219"	"GAPVD1"	"A8MYK3; B0QZ62; B0QZ63; B0QZ64; hsa:26130; Q14C76; Q14C86; Q2Q1W1; Q8ND92; Q8WU86; Q96CZ4; Q9NXQ1; Q9P207; Q9Y4N0"	""	"RAB GEFs exchange GTP for GDP on RABs; Clathrin-mediated endocytosis"	"2"	"0"	"57.7"	"44.0"	"56.8"	"56.2"	"64.6"	"50.8"	"70.5"	"82.5"	"141.7"	"326.9"	"550.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92665"	"28S ribosomal protein S31, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS31 PE=1 SV=3"	"9"	"3"	"8"	"3"	"395"	"45.3"	"9.29"	"1643.83"	"10.56"	"3"	"3"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf15433"	"10240"	"ENSG00000102738"	"MRPS31"	"B2RCS3; hsa:10240; Q5VYC8; Q8WTV8; Q92665"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"190.2"	"139.4"	"191.5"	"172.5"	"157.9"	"194.4"	"229.8"	"299.5"	"402.9"	"522.1"	"687.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NV70"	"Exocyst complex component 1 OS=Homo sapiens OX=9606 GN=EXOC1 PE=1 SV=4"	"5"	"3"	"5"	"3"	"894"	"101.9"	"6.61"	"936.28"	"10.55"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf09763, Pf15277"	"55763"	"ENSG00000090989"	"EXOC1"	"hsa:55763; Q504V4; Q8WUE7; Q96T15; Q9NV70; Q9NZE4"	"Ciliary landscape"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"4"	"0"	"2.1"	"11.5"	"14.6"	"10.6"	"15.6"	"20.8"	"38.9"	"62.4"	"209.8"	"289.9"	"313.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95391"	"Pre-mRNA-splicing factor SLU7 OS=Homo sapiens OX=9606 GN=SLU7 PE=1 SV=2"	"10"	"3"	"4"	"3"	"586"	"68.3"	"7.14"	"448.61"	"10.55"	"1"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;transport"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf11708"	"10569"	"ENSG00000164609"	"SLU7"	"D3DQK2; hsa:10569; O95391; Q3LUJ0; Q3LUJ1; Q6RXQ5; Q96FM9"	""	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"4"	"0"	"142.0"	"139.1"	"149.3"	"145.7"	"156.1"	"134.9"	"196.5"	"252.2"	"452.9"	"746.5"	"1075.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14531"	"Dihydropyrimidinase-related protein 4 OS=Homo sapiens OX=9606 GN=DPYSL4 PE=1 SV=2"	"6"	"3"	"8"	"3"	"572"	"61.8"	"7.09"	"1326.92"	"10.55"	"3"	"3"	"developmental processes"	"cytosol"	"cytoskeletal activity;other molecular function"	"Pf01979"	"10570"	"ENSG00000151640"	"DPYSL4"	"B2RMQ1; D3DRG5; hsa:10570; O00240; O14531; Q5T0Q7"	""	"CRMPs in Sema3A signaling"	"1"	"0"	"40.5"	"32.3"	"41.8"	"41.6"	"41.8"	"38.8"	"50.7"	"66.7"	"224.4"	"1359.1"	"2385.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13347"	"Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens OX=9606 GN=EIF3I PE=1 SV=1"	"10"	"3"	"5"	"3"	"325"	"36.5"	"5.64"	"579.76"	"10.54"	"2"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf00400"	"8668"	"ENSG00000084623"	"EIF3I"	"hsa:8668; Q13347"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"8"	"0"	"234.0"	"214.5"	"269.0"	"249.3"	"259.7"	"267.1"	"297.4"	"401.7"	"598.8"	"1037.3"	"2387.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BY89"	"Uncharacterized protein KIAA1671 OS=Homo sapiens OX=9606 GN=KIAA1671 PE=1 SV=2"	"2"	"2"	"4"	"2"	"1806"	"196.6"	"8.47"	"1243.21"	"10.53"	"2"	"2"	""	""	""	"Pf15327"	"85379"	"ENSG00000197077"	"KIAA1671"	"B0QYF2; B7ZW08; hsa:85379; Q5THZ5; Q9BY89"	""	""	"0"	"0"	"75.3"	"83.4"	"89.7"	"76.7"	"80.3"	"87.6"	"106.6"	"98.5"	"148.1"	"274.5"	"375.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UPT8"	"Zinc finger CCCH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=ZC3H4 PE=1 SV=3"	"4"	"3"	"4"	"3"	"1303"	"140.2"	"6.27"	"293.46"	"10.52"	"1"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00642, Pf14608, Pf18044"	"23211"	"ENSG00000130749"	"ZC3H4"	"hsa:23211; Q9UPT8; Q9Y420"	""	""	"0"	"0"	"47.5"	"54.5"	"45.1"	"44.2"	"50.1"	"46.2"	"59.4"	"68.6"	"107.2"	"203.0"	"286.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P10606"	"Cytochrome c oxidase subunit 5B, mitochondrial OS=Homo sapiens OX=9606 GN=COX5B PE=1 SV=2"	"29"	"3"	"6"	"3"	"129"	"13.7"	"8.81"	"1125.49"	"10.52"	"3"	"3"	"other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf01215"	"1329"	"ENSG00000135940"	"COX5B"	"hsa:1329; P10606; Q53YB7; Q96J18; Q99610"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex IV assembly; 5q35 copy number variation"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"7"	"0"	"190.7"	"190.4"	"186.5"	"175.4"	"177.8"	"172.7"	"198.9"	"234.0"	"408.8"	"944.6"	"1568.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96F85"	"CB1 cannabinoid receptor-interacting protein 1 OS=Homo sapiens OX=9606 GN=CNRIP1 PE=1 SV=1"	"27"	"2"	"2"	"2"	"164"	"18.6"	"7.94"	""	"10.51"	""	"2"	"other biological processes"	"plasma membrane;other membranes;other cell component"	"signal transduction activity or receptor binding"	"Pf15043"	"25927"	"ENSG00000119865"	"CNRIP1"	"B2R4D0; hsa:25927; Q49AN4; Q96F85; Q9UFZ0"	""	""	"0"	"0"	"5.7"	"12.8"	"16.5"	"14.8"	"24.0"	"41.0"	"66.9"	"92.5"	"159.7"	"174.9"	"207.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35914"	"Hydroxymethylglutaryl-CoA lyase, mitochondrial OS=Homo sapiens OX=9606 GN=HMGCL PE=1 SV=2"	"9"	"2"	"4"	"2"	"325"	"34.3"	"8.54"	"1072.81"	"10.50"	"2"	"2"	"cell organization and biogenesis;other metabolic processes"	"cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00682"	"3155"	"ENSG00000117305"	"HMGCL"	"B4DUP4; B7UCC6; D3Y5K7; hsa:3155; P35914; Q6IBC0; Q96FP8"	"Amino acid metabolism"	"Peroxisomal protein import; Synthesis of Ketone Bodies"	"3"	"0"	"96.3"	"80.2"	"100.5"	"88.1"	"104.8"	"110.1"	"117.6"	"163.1"	"375.8"	"738.1"	"1290.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52815"	"39S ribosomal protein L12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL12 PE=1 SV=2"	"18"	"3"	"6"	"3"	"198"	"21.3"	"8.87"	"916.59"	"10.49"	"3"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00542, Pf16320"	"6182"	"ENSG00000262814"	"MRPL12"	"hsa:6182; P52815; Q969U0; Q9HCA2; Q9UQJ3"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"58.0"	"48.5"	"69.5"	"54.2"	"65.6"	"61.7"	"78.9"	"129.7"	"305.8"	"556.6"	"935.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WVY7"	"Ubiquitin-like domain-containing CTD phosphatase 1 OS=Homo sapiens OX=9606 GN=UBLCP1 PE=1 SV=2"	"16"	"4"	"6"	"4"	"318"	"36.8"	"6.46"	"1110.11"	"10.47"	"3"	"3"	"protein metabolism;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00240, Pf03031"	"134510"	"ENSG00000164332"	"UBLCP1"	"D3DQJ7; hsa:134510; Q8WVY7; Q96DK5"	""	""	"0"	"0"	"67.9"	"56.9"	"95.7"	"73.7"	"85.0"	"78.1"	"101.1"	"133.9"	"973.3"	"2142.5"	"2330.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14795"	"Protein unc-13 homolog B OS=Homo sapiens OX=9606 GN=UNC13B PE=1 SV=2"	"3"	"4"	"7"	"4"	"1591"	"180.6"	"5.99"	"1516.07"	"10.45"	"4"	"3"	"cell-cell signaling;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00130, Pf00168, Pf06292"	"10497"	"ENSG00000198722"	"UNC13B"	"hsa:10497; O14795; Q2NKJ5; Q5VYM8"	"Synaptic vesicle pathway; 16p11.2 proximal deletion syndrome; Monoamine transport"	"Glutamate Neurotransmitter Release Cycle; Serotonin Neurotransmitter Release Cycle; Norepinephrine Neurotransmitter Release Cycle; Dopamine Neurotransmitter Release Cycle; Acetylcholine Neurotransmitter Release Cycle"	"8"	"0"	"41.6"	"30.7"	"47.7"	"39.1"	"47.0"	"63.0"	"104.3"	"232.6"	"523.7"	"440.2"	"439.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WUQ7"	"Cactin OS=Homo sapiens OX=9606 GN=CACTIN PE=1 SV=3"	"5"	"2"	"3"	"2"	"758"	"88.6"	"9.14"	"640.45"	"10.45"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf09732, Pf10312"	"58509"	"ENSG00000105298"	"CACTIN"	"A6NNA9; A9UL12; hsa:58509; O75229; Q7LE08; Q8WUQ7; Q9BTA6; Q9Y5A4"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"49.7"	"39.1"	"46.8"	"39.7"	"53.6"	"52.3"	"53.9"	"72.9"	"138.7"	"324.7"	"423.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IZP0"	"Abl interactor 1 OS=Homo sapiens OX=9606 GN=ABI1 PE=1 SV=4"	"8"	"3"	"5"	"3"	"508"	"55.0"	"7.06"	"1620.44"	"10.44"	"3"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00018, Pf07815"	"10006"	"ENSG00000136754"	"ABI1"	"A9Z1Y6; B3KX62; B4DQ58; H7BXI6; hsa:10006; O15147; O76049; O95060; Q5T2R3; Q5T2R4; Q5T2R6; Q5T2R7; Q5T2R9; Q5W070; Q5W072; Q8IZP0; Q8TB63; Q96S81; Q9NXZ9; Q9NYB8"	"EGF/EGFR signaling pathway"	"Regulation of actin dynamics for phagocytic cup formation; VEGFA-VEGFR2 Pathway; FCGR3A-mediated phagocytosis; RAC1 GTPase cycle; RHO GTPases Activate WASPs and WAVEs; RAC2 GTPase cycle; RAC3 GTPase cycle"	"8"	"0"	"119.1"	"132.1"	"138.8"	"99.8"	"121.3"	"127.7"	"169.0"	"250.4"	"501.0"	"624.6"	"720.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75940"	"Survival of motor neuron-related-splicing factor 30 OS=Homo sapiens OX=9606 GN=SMNDC1 PE=1 SV=1"	"17"	"3"	"5"	"3"	"238"	"26.7"	"7.24"	"587.65"	"10.43"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf06003"	"10285"	"ENSG00000119953"	"SMNDC1"	"B2RA27; D3DRB1; hsa:10285; O75940; Q5T3K6"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"257.3"	"221.0"	"255.6"	"208.4"	"294.6"	"250.1"	"318.1"	"367.0"	"715.7"	"869.6"	"815.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UJV9"	"Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2"	"6"	"4"	"6"	"4"	"622"	"69.8"	"6.84"	"557.13"	"10.43"	"2"	"4"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00270, Pf00271"	"51428"	"ENSG00000183258"	"DDX41"	"B2RDC8; hsa:51428; Q96BK6; Q96K05; Q9NT96; Q9NW04; Q9UJV9"	"5q35 copy number variation"	"mRNA Splicing - Major Pathway; Regulation of innate immune responses to cytosolic DNA; IRF3-mediated induction of type I IFN"	"5"	"0"	"213.9"	"233.7"	"235.6"	"180.6"	"200.8"	"216.0"	"247.8"	"296.4"	"488.1"	"1261.4"	"1988.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13984"	"General transcription factor IIF subunit 2 OS=Homo sapiens OX=9606 GN=GTF2F2 PE=1 SV=2"	"12"	"3"	"6"	"3"	"249"	"28.4"	"9.23"	"1008.25"	"10.41"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf02270, Pf17683"	"2963"	"ENSG00000188342"	"GTF2F2"	"A6NNS5; hsa:2963; P13984; Q5W0H3"	"Eukaryotic transcription initiation"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; mRNA Splicing - Major Pathway; Viral Messenger RNA Synthesis; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Estrogen-dependent gene expression; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM"	"33"	"0"	"202.5"	"183.5"	"201.7"	"186.5"	"243.7"	"232.5"	"263.5"	"306.4"	"573.0"	"893.6"	"1441.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08237"	"ATP-dependent 6-phosphofructokinase, muscle type OS=Homo sapiens OX=9606 GN=PFKM PE=1 SV=2"	"5"	"4"	"7"	"4"	"780"	"85.1"	"7.99"	"1422.44"	"10.39"	"4"	"3"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus"	"kinase activity;other molecular function"	"Pf00365"	"5213"	"ENSG00000152556"	"PFKM"	"hsa:5213; J3KNX3; P08237; Q16814; Q16815; Q6ZTT1"	"Clear cell renal cell carcinoma pathways; Aerobic glycolysis; Insulin signaling; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"Glycolysis"	"6"	"0"	"163.8"	"177.6"	"214.2"	"162.9"	"205.5"	"189.4"	"240.1"	"299.4"	"607.7"	"1156.5"	"1510.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09497"	"Clathrin light chain B OS=Homo sapiens OX=9606 GN=CLTB PE=1 SV=1"	"12"	"3"	"6"	"3"	"229"	"25.2"	"4.64"	"977.22"	"10.39"	"3"	"3"	"transport"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf01086"	"1212"	"ENSG00000175416"	"CLTB"	"hsa:1212; P09497; Q53Y37; Q6FHW1"	"Ebola virus infection in host; Fragile X syndrome; 5q35 copy number variation"	"Lysosome Vesicle Biogenesis; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; Formation of annular gap junctions"	"11"	"0"	"363.3"	"316.3"	"373.9"	"330.5"	"379.0"	"345.1"	"416.6"	"434.3"	"541.8"	"682.6"	"913.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14980"	"Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1"	"2"	"2"	"6"	"2"	"1071"	"123.3"	"6.06"	"1192.43"	"10.39"	"2"	"2"	"other metabolic processes;transport;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03810, Pf08389, Pf08767, Pf18777, Pf18784, Pf18787"	"7514"	"ENSG00000082898"	"XPO1"	"A6NL14; A8K1K5; D6W5E2; hsa:7514; O14980; Q63HP8; Q68CP3; Q99433"	"eIF5A regulation in response to inhibition of the nuclear export system; 22q11.2 copy number variation syndrome"	"Separation of Sister Chromatids; MAPK6/MAPK4 signaling; NPAS4 regulates expression of target genes; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Rev-mediated nuclear export of HIV RNA; NEP/NS2 Interacts with the Cellular Export Machinery; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Heme signaling; Deactivation of the beta-catenin transactivating complex; Estrogen-dependent nuclear events downstream of ESR-membrane signaling; Downregulation of TGF-beta receptor signaling; HuR (ELAVL1) binds and stabilizes mRNA; Cyclin A/B1/B2 associated events during G2/M transition"	"18"	"0"	"12.2"	"20.4"	"13.1"	"10.3"	"9.4"	"13.8"	"12.1"	"24.4"	"94.5"	"437.0"	"674.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75663"	"TIP41-like protein OS=Homo sapiens OX=9606 GN=TIPRL PE=1 SV=2"	"12"	"3"	"6"	"3"	"272"	"31.4"	"5.91"	"1162.51"	"10.39"	"3"	"3"	"stress response;signal transduction;other biological processes"	"cytosol"	""	"Pf04176"	"261726"	"ENSG00000143155"	"TIPRL"	"B2R8V3; hsa:261726; O75663; Q5HYB2; Q8IZ86"	"Ciliary landscape"	""	"1"	"0"	"358.9"	"386.0"	"437.9"	"374.5"	"413.0"	"431.1"	"494.9"	"597.9"	"794.3"	"1069.3"	"1348.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q03164"	"Histone-lysine N-methyltransferase 2A OS=Homo sapiens OX=9606 GN=KMT2A PE=1 SV=5"	"1"	"3"	"6"	"3"	"3969"	"431.5"	"9.09"	"1012.07"	"10.38"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00628, Pf00856, Pf02008, Pf05964, Pf05965, Pf13771"	"4297"	"ENSG00000118058"	"KMT2A"	"E9PQG7; hsa:4297; Q03164; Q13743; Q13744; Q14845; Q16364; Q59FF2; Q6UBD1; Q9HBJ3; Q9UD94; Q9UMA3"	"Histone modifications"	"RUNX1 regulates transcription of genes involved in differentiation of HSCs; Formation of WDR5-containing histone-modifying complexes; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Transcriptional regulation of granulopoiesis; PKMTs methylate histone lysines"	"6"	"0"	"65.3"	"72.8"	"80.3"	"69.7"	"82.6"	"80.4"	"86.9"	"113.1"	"275.6"	"531.9"	"671.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N0Z6"	"Tetratricopeptide repeat protein 5 OS=Homo sapiens OX=9606 GN=TTC5 PE=1 SV=2"	"8"	"2"	"3"	"2"	"440"	"48.9"	"6.48"	"519.42"	"10.36"	"1"	"2"	"DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf16669"	"91875"	"ENSG00000136319"	"TTC5"	"A8MQ18; hsa:91875; Q8N0Z6; Q96HF9"	""	"Regulation of TP53 Activity through Methylation"	"1"	"0"	"43.6"	"37.5"	"58.3"	"51.2"	"55.5"	"51.2"	"61.5"	"71.7"	"121.5"	"227.0"	"400.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UNH7"	"Sorting nexin-6 OS=Homo sapiens OX=9606 GN=SNX6 PE=1 SV=1"	"8"	"3"	"4"	"3"	"406"	"46.6"	"6.16"	"436.32"	"10.35"	"1"	"3"	"transport;other biological processes"	"other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00787, Pf09325"	"58533"	"ENSG00000129515"	"SNX6"	"C0H5W9; hsa:58533; Q9UNH7; Q9Y449"	""	""	"0"	"0"	"121.7"	"136.1"	"121.6"	"108.2"	"124.8"	"125.4"	"164.8"	"210.0"	"468.8"	"1862.2"	"3630.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQ52"	"Zinc phosphodiesterase ELAC protein 2 OS=Homo sapiens OX=9606 GN=ELAC2 PE=1 SV=2"	"6"	"4"	"7"	"4"	"826"	"92.2"	"7.90"	"1252.69"	"10.33"	"4"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf12706, Pf13691"	"60528"	"ENSG00000006744"	"ELAC2"	"B4DPL9; hsa:60528; Q6IA94; Q9BQ52; Q9HAS8; Q9HAS9; Q9NVT1"	""	"tRNA processing in the nucleus; tRNA processing in the mitochondrion; rRNA processing in the mitochondrion; tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis"	"4"	"0"	"33.8"	"36.0"	"41.9"	"32.7"	"39.1"	"40.2"	"53.9"	"79.6"	"235.4"	"662.8"	"1116.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P6C2"	"RNA demethylase ALKBH5 OS=Homo sapiens OX=9606 GN=ALKBH5 PE=1 SV=2"	"5"	"2"	"4"	"2"	"394"	"44.2"	"9.09"	"1256.06"	"10.32"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;ER/Golgi;nucleus"	"other molecular function"	"Pf13532"	"54890"	"ENSG00000091542"	"ALKBH5"	"B4DVJ4; D3DXC6; hsa:54890; Q6P6C2; Q9NXD6"	"Smith-Magenis and Potocki-Lupski syndrome copy number variation"	"Reversal of alkylation damage by DNA dioxygenases"	"2"	"0"	"81.7"	"75.4"	"53.7"	"51.6"	"68.5"	"63.3"	"81.2"	"89.3"	"97.7"	"117.3"	"133.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62979"	"Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2"	"30"	"4"	"7"	"4"	"156"	"18.0"	"9.64"	"1243.37"	"10.31"	"3"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;translational apparatus;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00240, Pf01599"	"6233"	"ENSG00000143947"	"RPS27A"	"hsa:6233; P02248; P02249; P02250; P14798; P62979; P62988; Q29120; Q6LBL4; Q6LDU5; Q8WYN8; Q91887; Q91888; Q9BQ77; Q9BWD6; Q9BX98; Q9UEF2; Q9UEG1; Q9UEK8; Q9UPK7"	"Cytoplasmic ribosomal proteins"	"Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Aggrephagy; Oxidative Stress Induced Senescence; ISG15 antiviral mechanism; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; InlA-mediated entry of Listeria monocytogenes into host cells; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; Recognition of DNA damage by PCNA-containing replication complex; Dual Incision in GG-NER; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER; Cargo recognition for clathrin-mediated endocytosis; EGFR downregulation; Negative regulation of MET activity; InlB-mediated entry of Listeria monocytogenes into host cell; Degradation of GLI1 by the proteasome; Hedgehog 'on' state; Activated NOTCH1 Transmits Signal to the Nucleus; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery; E3 ubiquitin ligases ubiquitinate target proteins; Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Stimuli-sensing channels; Amyloid fiber formation; Fanconi Anemia Pathway; Budding and maturation of HIV virion; Membrane binding and targetting of GAG proteins; Endosomal Sorting Complex Required For Transport (ESCRT); Late endosomal microautophagy; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Regulation of PLK1 Activity at G2/M Transition; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; NOTCH2 Activation and Transmission of Signal to the Nucleus; NOTCH3 Activation and Transmission of Signal to the Nucleus; Peroxisomal protein import; Regulation of TP53 Degradation; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Activation of IRF3, IRF7 mediated by TBK1, IKBKE; IKK complex recruitment mediated by RIP1; TRAF6-mediated induction of TAK1 complex within TLR4 complex; IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation; ER Quality Control Compartment (ERQC); SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Deactivation of the beta-catenin transactivating complex; Circadian Clock; Regulation of signaling by CBL; Metalloprotease DUBs; Regulation of necroptotic cell death; Oncogene Induced Senescence; Cyclin D associated events in G1; APC/C:Cdc20 mediated degradation of Cyclin B; APC-Cdc20 mediated degradation of Nek2A; Senescence-Associated Secretory Phenotype (SASP); Negative regulation of FLT3; Downregulation of ERBB2:ERBB3 signaling; Interferon alpha/beta signaling; Inactivation of CSF3 (G-CSF) signaling; JNK (c-Jun kinases) phosphorylation and  activation mediated by activated human TAK1; Regulation of TP53 Activity through Methylation; Regulation of BACH1 activity; NOD1/2 Signaling Pathway; TICAM1, RIP1-mediated IKK complex recruitment; p75NTR recruits signalling complexes; NF-kB is activated and signals survival; TAK1-dependent IKK and NF-kappa-B activation  ; Regulation of TNFR1 signaling; TNFR1-induced NF-kappa-B signaling pathway; MAP3K8 (TPL2)-dependent MAPK1/3 activation; IRAK1 recruits IKK complex; IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation; Regulation of NF-kappa B signaling; Negative regulators of DDX58/IFIH1 signaling; Prevention of phagosomal-lysosomal fusion; Downregulation of TGF-beta receptor signaling; Downregulation of SMAD2/3:SMAD4 transcriptional activity; Signaling by CSF1 (M-CSF) in myeloid cells; NOTCH1 Intracellular Domain Regulates Transcription; TICAM1-dependent activation of IRF3/IRF7; TICAM1,TRAF6-dependent induction of TAK1 complex; Glycogen synthesis; Formation of TC-NER Pre-Incision Complex; Modulation by Mtb of host immune system; activated TAK1 mediates p38 MAPK activation; IRAK2 mediated activation of TAK1 complex; SARS-CoV-1 activates/modulates innate immune responses; Alpha-protein kinase 1 signaling pathway; Ovarian tumor domain proteases; Spry regulation of FGF signaling; RAS processing; PINK1-PRKN Mediated Mitophagy; Josephin domain DUBs; Regulation of FZD by ubiquitination; Chaperone Mediated Autophagy; Formation of Incision Complex in GG-NER; Iron uptake and transport; VLDLR internalisation and degradation; Myoclonic epilepsy of Lafora; DNA Damage Recognition in GG-NER; Negative regulation of MAPK pathway; TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition); NRIF signals cell death from the nucleus; Assembly Of The HIV Virion; Downregulation of ERBB4 signaling; Regulation of innate immune responses to cytosolic DNA; N-glycan trimming in the ER and Calnexin/Calreticulin cycle; PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1; Regulation of PTEN localization; Pexophagy; Maturation of protein E; Maturation of protein E; FLT3 signaling by CBL mutants; TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling"	"201"	"0"	"888.8"	"963.3"	"957.0"	"866.9"	"1030.1"	"1051.4"	"1142.1"	"1254.2"	"1598.9"	"3080.5"	"5362.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P58107"	"Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3"	"2"	"2"	"3"	"1"	"5088"	"555.3"	"5.62"	"569.32"	"10.30"	"1"	"2"	"cell organization and biogenesis;stress response;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00681"	"83481"	"ENSG00000261150"	"EPPK1"	"A0A087X1U6; hsa:83481; P58107; Q76E58; Q9NSU9"	""	""	"0"	"0"	"11.2"	"11.3"	"11.4"	"15.0"	"17.7"	"17.5"	"18.5"	"13.4"	"17.1"	"24.8"	"23.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52756"	"RNA-binding protein 5 OS=Homo sapiens OX=9606 GN=RBM5 PE=1 SV=2"	"5"	"3"	"6"	"2"	"815"	"92.1"	"6.28"	"1077.50"	"10.28"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00641, Pf01585, Pf17780"	"10181"	"ENSG00000003756"	"RBM5"	"B2RA45; B4DM16; B4DMF9; B4DZ63; hsa:10181; P52756; Q93021; Q9BU14; Q9HDA6; Q9UKY8; Q9UL24"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"86.6"	"75.2"	"82.8"	"76.4"	"94.7"	"90.0"	"99.0"	"119.6"	"203.9"	"351.7"	"542.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O96000"	"NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 OS=Homo sapiens OX=9606 GN=NDUFB10 PE=1 SV=3"	"23"	"3"	"6"	"3"	"172"	"20.8"	"8.48"	"963.81"	"10.25"	"3"	"3"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf10249"	"4716"	"ENSG00000140990"	"NDUFB10"	"hsa:4716; O96000; Q96II6"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Modulators of TCR signaling and T cell activation; Oxidative phosphorylation"	"Complex I biogenesis"	"6"	"0"	"58.9"	"78.0"	"78.5"	"66.6"	"84.4"	"74.8"	"92.2"	"128.3"	"334.5"	"610.5"	"747.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13693"	"Translationally-controlled tumor protein OS=Homo sapiens OX=9606 GN=TPT1 PE=1 SV=1"	"9"	"1"	"2"	"1"	"172"	"19.6"	"4.93"	""	"10.25"	""	"1"	"transport;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00838"	"7178"	"ENSG00000133112"	"TPT1"	"B2R7E5; hsa:7178; P13693; Q6YLS2; Q7Z4J4; Q8TBK7; Q96EE2; Q9UC70"	""	""	"0"	"0"	"134.0"	"118.9"	"156.2"	"136.4"	"137.2"	"130.4"	"173.8"	"218.3"	"341.3"	"485.9"	"1202.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9ULH0"	"Kinase D-interacting substrate of 220 kDa OS=Homo sapiens OX=9606 GN=KIDINS220 PE=1 SV=3"	"1"	"2"	"6"	"2"	"1771"	"196.4"	"6.62"	"1226.31"	"10.25"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf07693, Pf12796"	"57498"	"ENSG00000134313"	"KIDINS220"	"A1L4N4; hsa:57498; Q4VC08; Q6MZU2; Q9H889; Q9H9E4; Q9NT37; Q9UF42; Q9ULH0"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; Neural crest cell migration in cancer"	"RND2 GTPase cycle; RND1 GTPase cycle; ARMS-mediated activation"	"5"	"0"	"47.1"	"22.6"	"43.8"	"42.7"	"43.9"	"48.2"	"56.8"	"84.8"	"233.2"	"401.2"	"530.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7L2E3"	"ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1"	"2"	"2"	"6"	"2"	"1194"	"133.9"	"8.78"	"1158.38"	"10.24"	"2"	"2"	"cell organization and biogenesis;developmental processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"22907"	"ENSG00000132153"	"DHX30"	"A8K5F1; hsa:22907; O94965; Q7L2E3; Q7Z753; Q96CH4; Q9NUQ0"	""	""	"0"	"0"	"56.3"	"42.1"	"65.6"	"68.8"	"74.4"	"62.0"	"75.6"	"121.3"	"185.8"	"255.6"	"366.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P20290"	"Transcription factor BTF3 OS=Homo sapiens OX=9606 GN=BTF3 PE=1 SV=1"	"26"	"2"	"2"	"2"	"206"	"22.2"	"9.38"	""	"10.22"	""	"2"	"transport;developmental processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	""	"Pf01849"	"689"	"ENSG00000145741"	"BTF3"	"A8K510; hsa:689; P20290; Q13893; Q76M56"	"Orexin receptor pathway"	""	"1"	"0"	"13.5"	"13.3"	"13.2"	"14.3"	"17.1"	"13.9"	"17.3"	"23.2"	"61.5"	"154.9"	"315.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q02543"	"60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2"	"14"	"3"	"8"	"3"	"176"	"20.7"	"10.71"	"1179.84"	"10.21"	"3"	"3"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01775"	"6142"	"ENSG00000105640"	"RPL18A"	"hsa:6142; Q02543"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"15"	"0"	"414.0"	"454.6"	"419.4"	"406.8"	"453.5"	"402.6"	"538.8"	"654.7"	"942.8"	"1692.1"	"3229.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQ39"	"ATP-dependent RNA helicase DDX50 OS=Homo sapiens OX=9606 GN=DDX50 PE=1 SV=1"	"6"	"3"	"4"	"2"	"737"	"82.5"	"9.17"	"647.32"	"10.21"	"2"	"2"	""	"plasma membrane;other membranes;nucleus"	"other molecular function"	"Pf00270, Pf00271, Pf08152"	"79009"	"ENSG00000107625"	"DDX50"	"hsa:79009; Q5VX37; Q8WV76; Q9BQ39; Q9BWI8"	""	""	"0"	"0"	"65.7"	"58.2"	"63.1"	"45.2"	"54.7"	"64.0"	"69.6"	"87.1"	"259.8"	"513.8"	"825.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09132"	"Signal recognition particle 19 kDa protein OS=Homo sapiens OX=9606 GN=SRP19 PE=1 SV=3"	"11"	"2"	"3"	"2"	"144"	"16.1"	"9.85"	"417.29"	"10.21"	"1"	"2"	"cell organization and biogenesis;transport"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01922"	"6728"	"ENSG00000153037"	"SRP19"	"B2R4E9; D6RCQ5; hsa:6728; P09132; Q05D77; Q96FG6"	""	"SRP-dependent cotranslational protein targeting to membrane"	"1"	"0"	"181.3"	"83.2"	"189.2"	"178.2"	"173.9"	"182.5"	"217.2"	"214.3"	"336.4"	"492.1"	"1205.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBQ5"	"Eukaryotic translation initiation factor 3 subunit K OS=Homo sapiens OX=9606 GN=EIF3K PE=1 SV=1"	"13"	"2"	"4"	"2"	"218"	"25.0"	"4.93"	"933.86"	"10.20"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf10075"	"27335"	"ENSG00000178982; ENSG00000282986"	"EIF3K"	"A8K0I9; B7ZAM9; hsa:27335; Q96IQ0; Q9UBQ5; Q9Y6D1"	""	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"6"	"0"	"71.8"	"84.1"	"74.3"	"65.8"	"83.1"	"65.2"	"90.5"	"123.5"	"274.8"	"620.1"	"2091.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4F1"	"FERM, ARHGEF and pleckstrin domain-containing protein 1 OS=Homo sapiens OX=9606 GN=FARP1 PE=1 SV=1"	"4"	"4"	"6"	"4"	"1045"	"118.6"	"8.15"	"1015.22"	"10.20"	"3"	"3"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00169, Pf00373, Pf00621, Pf08736, Pf09379, Pf09380"	"10160"	"ENSG00000152767"	"FARP1"	"hsa:10160; Q5JVI9; Q6IQ29; Q9Y4F1"	""	"RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOF GTPase cycle"	"4"	"0"	"365.6"	"255.0"	"356.1"	"327.0"	"365.3"	"373.4"	"398.5"	"444.3"	"669.9"	"1169.2"	"1683.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05204"	"Non-histone chromosomal protein HMG-17 OS=Homo sapiens OX=9606 GN=HMGN2 PE=1 SV=3"	"29"	"3"	"7"	"3"	"90"	"9.4"	"9.99"	"1573.35"	"10.17"	"3"	"3"	"cell organization and biogenesis;stress response;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01101"	"3151"	"ENSG00000198830"	"HMGN2"	"hsa:3151; P05204; Q0VGD5; Q6FGI5; Q96C64"	""	""	"0"	"0"	"419.6"	"291.8"	"435.3"	"359.3"	"176.0"	"347.3"	"462.3"	"520.7"	"499.9"	"256.8"	"233.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q04760"	"Lactoylglutathione lyase OS=Homo sapiens OX=9606 GN=GLO1 PE=1 SV=4"	"29"	"4"	"7"	"4"	"184"	"20.8"	"5.31"	"1705.69"	"10.17"	"4"	"3"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00903"	"2739"	"ENSG00000124767"	"GLO1"	"B2R6P7; B4DDV0; hsa:2739; P78375; Q04760; Q59EL0; Q5TZW3; Q96FC0; Q96J41"	""	"Pyruvate metabolism"	"1"	"0"	"182.9"	"311.7"	"237.9"	"237.1"	"200.4"	"188.2"	"251.5"	"384.3"	"550.7"	"863.1"	"931.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H9A5"	"CCR4-NOT transcription complex subunit 10 OS=Homo sapiens OX=9606 GN=CNOT10 PE=1 SV=1"	"4"	"2"	"3"	"2"	"744"	"82.3"	"7.78"	"395.83"	"10.16"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	""	"25904"	"ENSG00000182973"	"CNOT10"	"B7Z7L1; F8WAF2; hsa:25904; Q9BU30; Q9H5J7; Q9H8X1; Q9H9A5; Q9H9W0; Q9HAH3; Q9UFJ2"	"Ciliary landscape"	"Deadenylation of mRNA; TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"	"3"	"0"	"3.9"	"6.3"	"8.0"	"7.0"	"5.5"	"5.1"	"8.9"	"13.1"	"69.1"	"224.7"	"314.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60604"	"Ubiquitin-conjugating enzyme E2 G2 OS=Homo sapiens OX=9606 GN=UBE2G2 PE=1 SV=1"	"15"	"1"	"2"	"1"	"165"	"18.6"	"4.70"	""	"10.14"	""	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"ER/Golgi;other cell component"	"other molecular function"	"Pf00179"	"7327"	"ENSG00000184787"	"UBE2G2"	"A6NMQ7; A8K3L4; D3DSL7; hsa:7327; P56554; P60604"	"Parkin-ubiquitin proteasomal system pathway; Parkinson's disease pathway"	"Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Antigen processing: Ubiquitination & Proteasome degradation"	"4"	"0"	"12.6"	"15.4"	"16.7"	"17.6"	"19.5"	"17.3"	"16.2"	"28.9"	"57.8"	"101.9"	"144.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NYH9"	"U3 small nucleolar RNA-associated protein 6 homolog OS=Homo sapiens OX=9606 GN=UTP6 PE=2 SV=2"	"5"	"2"	"4"	"2"	"597"	"70.1"	"7.28"	"984.21"	"10.14"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf08640"	"55813"	"ENSG00000108651"	"UTP6"	"hsa:55813; Q8IX96; Q96BL2; Q9NQ91; Q9NYH9"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"56.7"	"70.8"	"64.0"	"46.9"	"67.5"	"68.6"	"72.7"	"104.2"	"276.8"	"591.7"	"814.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H0W5"	"Coiled-coil domain-containing protein 8 OS=Homo sapiens OX=9606 GN=CCDC8 PE=1 SV=2"	"9"	"2"	"2"	"2"	"538"	"59.3"	"8.63"	""	"10.14"	""	"2"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	""	"Pf14893"	"83987"	"ENSG00000169515"	"CCDC8"	"hsa:83987; Q8TB26; Q9H0W5"	""	"Neddylation"	"1"	"0"	"15.1"	"15.0"	"9.9"	"13.0"	"13.9"	"12.4"	"11.6"	"17.0"	"21.3"	"28.2"	"31.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94901"	"SUN domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SUN1 PE=1 SV=3"	"3"	"2"	"4"	"2"	"812"	"90.0"	"7.08"	"948.73"	"10.14"	"2"	"2"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"103.9"	"88.0"	"125.5"	"107.7"	"129.7"	"111.1"	"141.7"	"179.8"	"315.8"	"512.9"	"735.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07741"	"Adenine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=APRT PE=1 SV=2"	"21"	"2"	"4"	"2"	"180"	"19.6"	"6.02"	"836.15"	"10.13"	"2"	"2"	"other metabolic processes;transport;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00156"	"353"	"ENSG00000198931"	"APRT"	"G5E9J2; hsa:353; P07741; Q3KP55; Q68DF9"	""	"Neutrophil degranulation; Purine salvage; Defective APRT disrupts adenine salvage"	"3"	"0"	"21.3"	"19.3"	"31.3"	"17.9"	"24.2"	"25.8"	"27.4"	"43.0"	"90.9"	"190.6"	"356.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WXF0"	"Serine/arginine-rich splicing factor 12 OS=Homo sapiens OX=9606 GN=SRSF12 PE=2 SV=1"	"9"	"3"	"6"	"1"	"261"	"30.5"	"11.69"	"1351.64"	"10.11"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00076"	"135295"	"ENSG00000154548"	"SRSF12"	"B2RA22; hsa:135295; Q5T7K0; Q8WW25; Q8WXF0"	""	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"2"	"0"	"30.8"	"28.5"	"24.3"	"26.4"	"33.0"	"35.6"	"33.1"	"80.9"	"54.8"	"140.2"	"122.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50552"	"Vasodilator-stimulated phosphoprotein OS=Homo sapiens OX=9606 GN=VASP PE=1 SV=3"	"7"	"2"	"4"	"2"	"380"	"39.8"	"8.94"	"1172.75"	"10.09"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00568, Pf08776"	"7408"	"ENSG00000125753"	"VASP"	"B2RBT9; hsa:7408; P50552; Q6PIZ1; Q93035"	"Integrin-mediated cell adhesion; Focal adhesion"	"Generation of second messenger molecules; Signaling by ROBO receptors; Cell-extracellular matrix interactions"	"5"	"0"	"39.2"	"34.1"	"42.1"	"34.4"	"36.6"	"36.4"	"40.1"	"55.3"	"63.2"	"115.9"	"156.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P41240"	"Tyrosine-protein kinase CSK OS=Homo sapiens OX=9606 GN=CSK PE=1 SV=1"	"8"	"3"	"4"	"3"	"450"	"50.7"	"7.06"	"444.29"	"10.09"	"1"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00017, Pf00018, Pf07714"	"1445"	"ENSG00000103653"	"CSK"	"hsa:1445; P41240; Q2M3N2; Q6FGZ6"	"Integrin-mediated cell adhesion; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; EGF/EGFR signaling pathway; Regulation of actin cytoskeleton"	"Signaling by BRAF and RAF1 fusions; GAB1 signalosome; Integrin signaling; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; Negative regulation of FLT3; Phosphorylation of CD3 and TCR zeta chains; PD-1 signaling; RHOH GTPase cycle"	"18"	"0"	"56.0"	"61.4"	"62.2"	"57.7"	"58.6"	"55.6"	"62.8"	"83.4"	"178.6"	"764.2"	"1497.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62861"	"40S ribosomal protein S30 OS=Homo sapiens OX=9606 GN=FAU PE=1 SV=1"	"20"	"3"	"6"	"3"	"59"	"6.6"	"12.15"	"1114.80"	"10.09"	"3"	"3"	"protein metabolism;other metabolic processes;stress response"	"non-structural extracellular;cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf04758"	""	"ENSCHIG00000017446; ENSJHYG00000000624; ENSLLEG00000000574"	"Fau; FAU"	"A0A452F0A8; A0A7L0YXB0; A0A8C5IE60; A0A8C5LQJ8; P0C2F0; P62860; P62863; P62864; P62866; P62867; Q05472; Q5RC12; Q8HYI8; Q920W7; Q95261"	""	""	"0"	"0"	"224.1"	"199.3"	"224.6"	"193.3"	"217.5"	"227.9"	"258.2"	"267.2"	"351.8"	"529.1"	"625.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y606"	"tRNA pseudouridine synthase A OS=Homo sapiens OX=9606 GN=PUS1 PE=1 SV=3"	"16"	"5"	"8"	"5"	"427"	"47.4"	"8.41"	"1744.30"	"10.06"	"5"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01416"	"80324"	"ENSG00000177192"	"PUS1"	"A8K877; B3KQC1; hsa:80324; Q8WYT2; Q9BU44; Q9Y606"	""	""	"0"	"0"	"69.2"	"62.7"	"99.0"	"72.7"	"91.7"	"94.3"	"100.4"	"126.1"	"374.3"	"518.6"	"482.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00232"	"26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3"	"9"	"3"	"5"	"3"	"456"	"52.9"	"7.65"	"579.99"	"10.06"	"2"	"3"	"protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	""	"Pf01399, Pf18098"	"5718"	"ENSG00000197170"	"PSMD12"	"A6NP15; hsa:5718; O00232; Q53HA2; Q6P053"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Ciliary landscape; Alzheimer's disease"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"65"	"0"	"22.7"	"27.6"	"36.3"	"28.6"	"29.5"	"28.9"	"33.7"	"41.9"	"96.4"	"198.4"	"387.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EY8"	"Corrinoid adenosyltransferase OS=Homo sapiens OX=9606 GN=MMAB PE=1 SV=1"	"10"	"2"	"6"	"2"	"250"	"27.4"	"8.60"	"1518.54"	"10.06"	"2"	"2"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf01923"	"326625"	"ENSG00000139428"	"MMAB"	"C5HU05; hsa:326625; Q96EY8; Q9BSH0"	"Vitamin B12 metabolism"	"Cobalamin (Cbl) metabolism; Defective MMAB causes MMA, cblB type"	"3"	"0"	"93.4"	"79.9"	"98.3"	"96.5"	"93.3"	"102.6"	"111.7"	"163.9"	"787.0"	"1251.3"	"1415.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P41214"	"Eukaryotic translation initiation factor 2D OS=Homo sapiens OX=9606 GN=EIF2D PE=1 SV=3"	"9"	"4"	"6"	"4"	"584"	"64.7"	"7.65"	"1133.82"	"10.04"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01253, Pf17832"	"1939"	"ENSG00000143486"	"EIF2D"	"hsa:1939; P41214; Q5SY40; Q8IXV3; Q96DG3; Q96TG7; Q9NR27; Q9NSN0; Q9NV18; Q9NZ21"	""	""	"0"	"0"	"194.9"	"168.5"	"194.1"	"178.4"	"194.2"	"188.6"	"223.0"	"281.7"	"633.2"	"914.0"	"1010.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43301"	"Heat shock 70 kDa protein 12A OS=Homo sapiens OX=9606 GN=HSPA12A PE=1 SV=2"	"6"	"3"	"4"	"3"	"675"	"74.9"	"6.77"	"238.27"	"10.03"	"1"	"3"	""	"nucleus;other cell component"	"other molecular function"	""	"259217"	"ENSG00000165868"	"HSPA12A"	"hsa:259217; O43301"	""	"Regulation of HSF1-mediated heat shock response"	"1"	"0"	"71.1"	"69.8"	"65.9"	"70.0"	"78.5"	"71.3"	"85.3"	"115.6"	"241.4"	"441.9"	"560.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H2H8"	"Peptidyl-prolyl cis-trans isomerase-like 3 OS=Homo sapiens OX=9606 GN=PPIL3 PE=1 SV=1"	"30"	"5"	"9"	"5"	"161"	"18.1"	"6.79"	"1744.66"	"10.03"	"5"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00160"	"53938"	"ENSG00000240344"	"PPIL3"	"hsa:53938; Q86WF9; Q96IA9; Q9BXZ1; Q9H2H8"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"475.2"	"439.9"	"479.3"	"427.0"	"515.7"	"479.4"	"557.0"	"713.9"	"1455.4"	"2274.7"	"2825.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9GZT9"	"Egl nine homolog 1 OS=Homo sapiens OX=9606 GN=EGLN1 PE=1 SV=1"	"9"	"3"	"6"	"3"	"426"	"46.0"	"8.53"	"1246.27"	"10.02"	"3"	"3"	"protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01753, Pf13640"	"54583"	"ENSG00000135766"	"EGLN1"	"hsa:54583; Q8N3M8; Q9BZS8; Q9BZT0; Q9GZT9"	"Photodynamic therapy-induced HIF-1 survival signaling; Type 2 papillary renal cell carcinoma; Markers of kidney cell lineage"	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"	"4"	"0"	"178.2"	"171.5"	"178.3"	"162.3"	"187.7"	"147.0"	"198.4"	"260.7"	"446.5"	"674.2"	"844.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15853"	"Upstream stimulatory factor 2 OS=Homo sapiens OX=9606 GN=USF2 PE=1 SV=1"	"10"	"3"	"6"	"2"	"346"	"36.9"	"5.10"	"992.04"	"10.00"	"3"	"3"	"transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00010"	"7392"	"ENSG00000105698"	"USF2"	"hsa:7392; O00671; O00709; Q05750; Q07952; Q15851; Q15852; Q15853; Q6FI33; Q6YI47"	"Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4)"	"Estrogen-dependent gene expression"	"2"	"1"	"194.2"	"163.3"	"217.0"	"160.8"	"193.6"	"187.4"	"225.4"	"291.2"	"597.5"	"933.3"	"1183.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P27708"	"CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3"	"2"	"3"	"5"	"3"	"2225"	"242.8"	"6.46"	"780.91"	"9.91"	"2"	"3"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00117, Pf00185, Pf00988, Pf01979, Pf02142, Pf02729, Pf02786, Pf02787"	"790"	"ENSG00000084774"	"CAD"	"D6W552; hsa:790; P27708; Q6P0Q0; Q96CK3"	"Endothelin pathways; Amino acid metabolism; Pyrimidine metabolism"	"Pyrimidine biosynthesis"	"4"	"0"	"87.5"	"82.7"	"106.2"	"86.2"	"85.6"	"93.1"	"124.3"	"136.4"	"233.0"	"568.9"	"963.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23258"	"Tubulin gamma-1 chain OS=Homo sapiens OX=9606 GN=TUBG1 PE=1 SV=2"	"12"	"4"	"8"	"4"	"451"	"51.1"	"6.14"	"1967.82"	"9.90"	"4"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis"	"cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00091, Pf03953"	"7283"	"ENSG00000131462"	"TUBG1"	"hsa:7283; P23258; Q53X79; Q9BW59"	"Alstrom syndrome"	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"8"	"0"	"243.7"	"234.7"	"296.3"	"256.3"	"255.1"	"303.2"	"378.7"	"631.5"	"1737.1"	"1798.0"	"1548.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75530"	"Polycomb protein EED OS=Homo sapiens OX=9606 GN=EED PE=1 SV=2"	"5"	"2"	"6"	"2"	"441"	"50.2"	"7.03"	"867.67"	"9.89"	"2"	"2"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00400"	"8726"	"ENSG00000074266"	"EED"	"A8K7V5; hsa:8726; O00149; O75530; Q6NTH2; Q7LDA5; Q7LDG8; Q86VV2; Q9UNY7"	"Histone modifications; Interactome of polycomb repressive complex 2 (PRC2) ; Tumor suppressor activity of SMARCB1; Epithelial to mesenchymal transition in colorectal cancer; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; Pleural mesothelioma; 5q35 copy number variation"	"HCMV Early Events; Oxidative Stress Induced Senescence; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6; Activation of anterior HOX genes in hindbrain development during early embryogenesis; PKMTs methylate histone lysines; PRC2 methylates histones and DNA; Defective pyroptosis"	"15"	"0"	"14.1"	"18.5"	"22.7"	"15.6"	"20.9"	"26.2"	"32.0"	"35.2"	"82.8"	"301.5"	"428.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P27797"	"Calreticulin OS=Homo sapiens OX=9606 GN=CALR PE=1 SV=1"	"12"	"4"	"6"	"4"	"417"	"48.1"	"4.44"	"900.34"	"9.87"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;extracellular matrix;plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00262"	"811"	"ENSG00000179218"	"CALR"	"hsa:811; P27797; Q6IAT4; Q9UDG2"	"Androgen receptor signaling pathway; Complement system; Photodynamic therapy-induced unfolded protein response; VEGFA-VEGFR2 signaling; GDNF signaling; Calcium regulation in cardiac cells"	"Scavenging by Class A Receptors; Scavenging by Class F Receptors; ER-Phagosome pathway; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Assembly of Viral Components at the Budding Site; ATF6 (ATF6-alpha) activates chaperone genes; Calnexin/calreticulin cycle"	"13"	"0"	"398.1"	"334.6"	"442.5"	"353.6"	"408.1"	"415.9"	"470.5"	"500.1"	"597.5"	"786.9"	"924.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15031"	"Probable leucine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=LARS2 PE=1 SV=2"	"6"	"3"	"4"	"3"	"903"	"101.9"	"8.22"	"281.59"	"9.85"	"1"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00133, Pf08264"	"23395"	"ENSG00000011376"	"LARS2"	"hsa:23395; Q15031"	"Amino acid metabolism; IL-18 signaling pathway; Primary ovarian insufficiency"	"Mitochondrial tRNA aminoacylation"	"4"	"0"	"22.3"	"16.4"	"23.0"	"26.4"	"21.3"	"27.1"	"27.2"	"36.9"	"99.9"	"208.0"	"235.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2D4"	"Exocyst complex component 6B OS=Homo sapiens OX=9606 GN=EXOC6B PE=1 SV=3"	"4"	"3"	"5"	"3"	"811"	"94.1"	"6.46"	"773.77"	"9.85"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport"	"other cell component"	""	"Pf04091"	"23233"	"ENSG00000144036"	"EXOC6B"	"B8ZZY3; hsa:23233; Q9Y2D4"	"Ciliary landscape"	""	"1"	"0"	"34.5"	"27.3"	"37.7"	"30.8"	"37.4"	"44.6"	"57.4"	"99.2"	"229.9"	"354.5"	"415.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P0C0S5"	"Histone H2A.Z OS=Homo sapiens OX=9606 GN=H2AZ1 PE=1 SV=2"	"20"	"2"	"8"	"1"	"128"	"13.5"	"10.58"	"1323.94"	"9.84"	"2"	"2"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125, Pf16211"	"3015"	"ENSG00000164032"	"H2AZ1"	"B2RD56; hsa:3015; P0C0S5; P17317; Q6I9U0"	"Proteasome degradation; Retinoblastoma gene in cancer; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma"	"Amyloid fiber formation"	"4"	"0"	"52.1"	"41.0"	"57.5"	"56.0"	"49.1"	"61.4"	"67.3"	"79.2"	"105.8"	"154.0"	"218.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P28066"	"Proteasome subunit alpha type-5 OS=Homo sapiens OX=9606 GN=PSMA5 PE=1 SV=3"	"11"	"2"	"6"	"2"	"241"	"26.4"	"4.79"	"1182.07"	"9.82"	"2"	"2"	"protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	""	"Pf00227, Pf10584"	"5686"	"ENSG00000143106"	"PSMA5"	"B2R8F6; B4E2V4; hsa:5686; P28066; Q3T1C1; Q6IBF7"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"63"	"0"	"55.6"	"41.2"	"48.3"	"47.6"	"41.3"	"47.4"	"62.4"	"78.4"	"140.4"	"289.4"	"708.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P26640"	"Valine--tRNA ligase OS=Homo sapiens OX=9606 GN=VARS1 PE=1 SV=4"	"3"	"4"	"6"	"4"	"1264"	"140.4"	"7.59"	"1279.42"	"9.81"	"3"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol"	"other molecular function"	"Pf00043, Pf00133, Pf08264"	"7407"	"ENSG00000096171; ENSG00000204394; ENSG00000224264; ENSG00000226589; ENSG00000231116"	"VARS1"	"B0V1N1; B4DZ61; hsa:7407; P26640; Q5JQ90; Q96E77; Q9UQM2"	"Amino acid metabolism"	"Cytosolic tRNA aminoacylation"	"2"	"0"	"402.4"	"362.1"	"436.6"	"375.2"	"400.5"	"460.2"	"519.1"	"551.8"	"643.8"	"928.4"	"1369.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96J02"	"E3 ubiquitin-protein ligase Itchy homolog OS=Homo sapiens OX=9606 GN=ITCH PE=1 SV=2"	"4"	"3"	"4"	"3"	"903"	"102.7"	"6.30"	"357.72"	"9.80"	"1"	"3"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00168, Pf00397, Pf00632"	"83737"	"ENSG00000078747"	"ITCH"	"A6NEW4; B4E234; E1P5P3; F5H217; hsa:83737; O43584; Q5QP37; Q5TEL0; Q96F66; Q96J02; Q9BY75; Q9H451; Q9H4U5"	"VEGFA-VEGFR2 signaling; EGF/EGFR signaling pathway; Nonalcoholic fatty liver disease; 10q11.21q11.23 copy number variation syndrome; Notch signaling pathway"	"SARS-CoV-1 activates/modulates innate immune responses; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Antigen processing: Ubiquitination & Proteasome degradation; Degradation of GLI1 by the proteasome; Hedgehog 'on' state; Negative regulators of DDX58/IFIH1 signaling; Activated NOTCH1 Transmits Signal to the Nucleus; Regulation of necroptotic cell death; NOD1/2 Signaling Pathway; Downregulation of ERBB4 signaling"	"15"	"0"	"17.7"	"13.5"	"22.7"	"22.7"	"22.1"	"22.9"	"23.2"	"39.1"	"85.9"	"231.4"	"356.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95881"	"Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1"	"18"	"3"	"5"	"3"	"172"	"19.2"	"5.40"	"916.79"	"9.79"	"2"	"3"	"other biological processes"	"ER/Golgi"	"other molecular function"	"Pf13899"	"51060"	"ENSG00000117862"	"TXNDC12"	"B3KQS0; hsa:51060; O95881; Q5T1T4; Q96H50"	""	""	"0"	"0"	"423.7"	"360.5"	"475.6"	"426.2"	"474.2"	"464.7"	"543.0"	"679.0"	"831.4"	"934.4"	"1183.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92797"	"Symplekin OS=Homo sapiens OX=9606 GN=SYMPK PE=1 SV=2"	"3"	"2"	"3"	"2"	"1274"	"141.1"	"6.13"	"560.99"	"9.75"	"1"	"2"	"cell adhesion;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	""	"Pf11935, Pf12295"	"8189"	"ENSG00000125755"	"SYMPK"	"hsa:8189; O00521; O00689; O00733; Q59GT5; Q8N2U5; Q92797"	""	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA Derived from an Intronless Transcript; Processing of Intronless Pre-mRNAs"	"5"	"0"	"69.9"	"60.2"	"75.4"	"78.6"	"73.9"	"69.1"	"75.0"	"99.0"	"213.0"	"410.8"	"657.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N6M0"	"Deubiquitinase OTUD6B OS=Homo sapiens OX=9606 GN=OTUD6B PE=1 SV=1"	"11"	"3"	"6"	"3"	"293"	"33.8"	"6.05"	"1092.75"	"9.70"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	""	"other molecular function"	"Pf02338"	"51633"	"ENSG00000155100"	"OTUD6B"	"A8K6I1; B4DEY0; hsa:51633; Q8N6M0; Q9NTA4; Q9Y387"	"Warburg effect modulated by deubiquitinating enzymes and their substrates"	""	"1"	"0"	"82.8"	"63.7"	"117.4"	"88.7"	"104.7"	"109.7"	"135.2"	"205.4"	"1173.1"	"1629.8"	"1541.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75970"	"Multiple PDZ domain protein OS=Homo sapiens OX=9606 GN=MPDZ PE=1 SV=2"	"2"	"3"	"5"	"3"	"2070"	"221.5"	"5.06"	"573.13"	"9.67"	"2"	"3"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;other cell component"	""	"Pf00595, Pf09045, Pf16667"	"8777"	"ENSG00000107186"	"MPDZ"	"A6NLC2; B2RTS3; B7ZMI4; hsa:8777; O43798; O75970; Q4LE30; Q5CZ80; Q5JTX3; Q5JTX6; Q5JTX7; Q5JUC3; Q5JUC4; Q5VZ62; Q8N790"	""	""	"0"	"0"	"112.9"	"130.8"	"124.4"	"89.9"	"101.5"	"132.2"	"155.8"	"169.8"	"401.4"	"877.4"	"1339.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P40429"	"60S ribosomal protein L13a OS=Homo sapiens OX=9606 GN=RPL13A PE=1 SV=2"	"13"	"3"	"7"	"3"	"203"	"23.6"	"10.93"	"1202.02"	"9.66"	"3"	"2"	"protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00572"	"23521"	"ENSG00000142541"	"RPL13A"	"A8K505; hsa:23521; P40429"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis"	"15"	"0"	"315.8"	"367.3"	"320.0"	"264.5"	"319.6"	"364.8"	"432.9"	"599.9"	"889.4"	"1841.5"	"2882.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UJS0"	"Calcium-binding mitochondrial carrier protein Aralar2 OS=Homo sapiens OX=9606 GN=SLC25A13 PE=1 SV=2"	"4"	"2"	"5"	"2"	"675"	"74.1"	"8.62"	"1345.53"	"9.65"	"2"	"1"	"other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00153"	"10165"	"ENSG00000004864"	"SLC25A13"	"hsa:10165; O14566; O14575; Q546F9; Q9NZW1; Q9UJS0; Q9UNI7"	""	"Gluconeogenesis; Mitochondrial protein import; Aspartate and asparagine metabolism"	"3"	"0"	"107.5"	"131.3"	"112.2"	"108.2"	"120.4"	"129.9"	"128.1"	"183.4"	"347.8"	"646.2"	"770.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62906"	"60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2"	"15"	"3"	"6"	"3"	"217"	"24.8"	"9.94"	"1104.59"	"9.65"	"3"	"3"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf00687"	"4736"	"ENSG00000198755"	"RPL10A"	"B2R801; hsa:4736; P52859; P53025; P62906; Q5TZT6; Q8J013"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Selenocysteine synthesis; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"15"	"0"	"166.9"	"206.2"	"216.0"	"179.4"	"181.9"	"193.9"	"233.2"	"359.3"	"593.1"	"1208.5"	"2000.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14950"	"Myosin regulatory light chain 12B OS=Homo sapiens OX=9606 GN=MYL12B PE=1 SV=2"	"23"	"2"	"3"	"2"	"172"	"19.8"	"4.84"	"427.40"	"9.65"	"1"	"1"	"other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf08976, Pf13405"	"103910; 10627"	"ENSG00000118680"	"MYL12B"	"D3DUH6; hsa:103910; O14950; Q13182; Q7Z5Z4"	"Thyroid stimulating hormone (TSH) signaling pathway; Focal adhesion"	"RHO GTPases activate CIT; EPHA-mediated growth cone collapse; Sema4D induced cell migration and growth-cone collapse; Smooth Muscle Contraction; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; RHO GTPases activate PAKs"	"9"	"0"	"75.6"	"55.7"	"86.4"	"76.1"	"76.3"	"89.6"	"89.4"	"103.9"	"174.0"	"717.8"	"1736.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H4M9"	"EH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=EHD1 PE=1 SV=2"	"10"	"3"	"5"	"3"	"534"	"60.6"	"6.83"	"548.61"	"9.64"	"1"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00350, Pf12763, Pf16880, Pf18150"	"10938"	"ENSG00000110047"	"EHD1"	"hsa:10938; O14611; Q2M3Q4; Q9H4M9; Q9UNR3"	"Insulin signaling"	"Factors involved in megakaryocyte development and platelet production"	"2"	"0"	"58.6"	"65.0"	"65.7"	"69.5"	"68.2"	"65.9"	"82.1"	"131.1"	"370.5"	"530.3"	"569.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00584"	"Ribonuclease T2 OS=Homo sapiens OX=9606 GN=RNASET2 PE=1 SV=2"	"12"	"2"	"4"	"2"	"256"	"29.5"	"7.08"	"980.11"	"9.63"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;stress response"	"non-structural extracellular;mitochondrion;ER/Golgi;other cytoplasmic organelle"	"nucleic acid binding activity;other molecular function"	"Pf00445"	"8635"	"ENSG00000026297"	"RNASET2"	"B2RDA7; E1P5C3; hsa:8635; O00584; Q5T8Q0; Q8TCU2; Q9BZ46; Q9BZ47"	""	"Neutrophil degranulation"	"1"	"0"	"14.3"	"15.3"	"15.3"	"15.7"	"21.2"	"13.5"	"16.7"	"21.5"	"81.1"	"585.0"	"1181.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UNS1"	"Protein timeless homolog OS=Homo sapiens OX=9606 GN=TIMELESS PE=1 SV=2"	"3"	"3"	"6"	"3"	"1208"	"138.6"	"5.40"	"1032.86"	"9.58"	"3"	"3"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04821, Pf05029"	"8914"	"ENSG00000111602"	"TIMELESS"	"B2ZAV0; hsa:8914; O94802; Q86VM1; Q8IWH3; Q9UNS1"	""	"Processing of DNA double-strand break ends"	"1"	"0"	"42.4"	"42.1"	"52.0"	"44.6"	"49.6"	"52.9"	"59.9"	"87.1"	"154.8"	"649.2"	"1348.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14923"	"Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3"	"5"	"3"	"6"	"2"	"745"	"81.7"	"6.14"	"1169.35"	"9.58"	"2"	"2"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00514"	"3728"	"ENSG00000173801"	"JUP"	"hsa:3728; P14923; Q15093; Q15151; Q7L3S5; Q86W21; Q9BWC4; Q9HCX9"	"Arrhythmogenic right ventricular cardiomyopathy; Corticotropin-releasing hormone signaling pathway; Ectoderm differentiation; Ectoderm differentiation; Epithelial to mesenchymal transition in colorectal cancer; Opioid receptor pathways"	"RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RHOB GTPase cycle; Formation of the cornified envelope; RHOQ GTPase cycle; RHOJ GTPase cycle; Neutrophil degranulation; VEGFR2 mediated vascular permeability; Adherens junctions interactions; Regulation of CDH11 function; Regulation of CDH19 Expression and Function; CDH11 homotypic and heterotypic interactions; RHOH GTPase cycle"	"21"	"0"	"89.0"	"96.8"	"144.2"	"104.7"	"128.4"	"95.8"	"134.0"	"180.7"	"357.4"	"660.9"	"1020.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13330"	"Metastasis-associated protein MTA1 OS=Homo sapiens OX=9606 GN=MTA1 PE=1 SV=2"	"6"	"4"	"7"	"4"	"715"	"80.7"	"9.26"	"1362.68"	"9.58"	"4"	"3"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00249, Pf00320, Pf01426, Pf01448, Pf17226"	"9112"	"ENSG00000182979"	"MTA1"	"A5PLK4; hsa:9112; Q13330; Q86SW2; Q8NFI8; Q96GI8"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; TAR syndrome"	"HDACs deacetylate histones; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of PTEN gene transcription; Potential therapeutics for SARS; RNA Polymerase I Transcription Initiation; SUMOylation of transcription factors"	"8"	"0"	"133.2"	"114.4"	"151.9"	"126.1"	"142.6"	"142.1"	"157.3"	"227.7"	"405.0"	"682.5"	"1063.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14690"	"Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3"	"2"	"3"	"5"	"3"	"1871"	"208.6"	"8.87"	"703.09"	"9.56"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00575, Pf05843"	"22984"	"ENSG00000148843"	"PDCD11"	"hsa:22984; Q14690; Q2TA92; Q5W093; Q6P2J3; Q86VQ8; Q9H4P1"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"52.7"	"51.3"	"52.3"	"50.0"	"63.3"	"52.2"	"62.7"	"77.9"	"104.4"	"184.3"	"280.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q3B726"	"DNA-directed RNA polymerase I subunit RPA43 OS=Homo sapiens OX=9606 GN=TWISTNB PE=1 SV=1"	"8"	"2"	"4"	"2"	"338"	"37.4"	"6.98"	"906.26"	"9.53"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	"Pf17875"	"221830"	"ENSG00000105849"	"POLR1F"	"A0PJ45; B7Z724; hsa:221830; Q3B726"	"Pyrimidine metabolism; 2q13 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"7"	"0"	"18.3"	"11.6"	"24.9"	"15.5"	"24.4"	"30.1"	"26.7"	"33.4"	"286.9"	"601.3"	"614.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13555"	"Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sapiens OX=9606 GN=CAMK2G PE=1 SV=4"	"5"	"3"	"7"	"2"	"558"	"62.6"	"7.83"	"1368.82"	"9.53"	"3"	"2"	"cell-cell signaling;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf08332"	"818"	"ENSG00000148660"	"CAMK2G"	"A0A0A0MS52; A0A0A0MT11; hsa:818; O00561; O15378; Q13279; Q13282; Q13555; Q13556; Q5SQZ3; Q5SQZ4; Q5SWX4; Q7KYX5; Q8N4I3; Q8NIA4"	"Energy metabolism; Myometrial relaxation and contraction pathways; NO/cGMP/PKG mediated neuroprotection; Splicing factor NOVA regulated synaptic proteins; Wnt signaling; Non-genomic actions of 1,25 dihydroxyvitamin D3; Disruption of postsynaptic signaling by CNV; Neuroinflammation and glutamatergic signaling; Calcium regulation in cardiac cells; ErbB signaling pathway"	"Ion homeostasis; Ion transport by P-type ATPases; Assembly and cell surface presentation of NMDA receptors; Signaling by BRAF and RAF1 fusions; Interferon gamma signaling; RAF activation; Ras activation upon Ca2+ influx through NMDA receptor; Regulation of MECP2 expression and activity; Unblocking of NMDA receptors, glutamate binding and activation; Negative regulation of NMDA receptor-mediated neuronal transmission; Long-term potentiation; Trafficking of AMPA receptors; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; Phase 0 - rapid depolarisation; HSF1-dependent transactivation; CaMK IV-mediated phosphorylation of CREB; CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde"	"31"	"0"	"91.2"	"111.0"	"115.5"	"99.2"	"112.1"	"107.9"	"135.1"	"176.3"	"362.4"	"815.0"	"1165.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96SB8"	"Structural maintenance of chromosomes protein 6 OS=Homo sapiens OX=9606 GN=SMC6 PE=1 SV=2"	"3"	"3"	"7"	"3"	"1091"	"126.2"	"6.99"	"1571.71"	"9.52"	"3"	"3"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02463"	"79677"	"ENSG00000163029"	"SMC6"	"A8K8Q6; D6W518; hsa:79677; Q05BV4; Q96SB8; Q9H0X3; Q9H6M0"	""	"SUMOylation of DNA damage response and repair proteins"	"1"	"0"	"32.2"	"33.3"	"47.4"	"37.0"	"42.5"	"40.2"	"52.2"	"66.9"	"148.9"	"362.7"	"455.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q05682"	"Caldesmon OS=Homo sapiens OX=9606 GN=CALD1 PE=1 SV=3"	"6"	"5"	"8"	"5"	"793"	"93.2"	"5.66"	"1576.22"	"9.52"	"5"	"3"	"cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton"	"cytoskeletal activity;other molecular function"	"Pf02029"	"800"	"ENSG00000122786"	"CALD1"	"A8K0X1; hsa:800; Q05682; Q13978; Q13979; Q14741; Q14742; Q9UD91"	"Myometrial relaxation and contraction pathways"	"Smooth Muscle Contraction"	"2"	"0"	"400.0"	"363.7"	"380.2"	"339.1"	"373.1"	"403.9"	"462.5"	"486.4"	"1197.0"	"2459.8"	"3327.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P42356"	"Phosphatidylinositol 4-kinase alpha OS=Homo sapiens OX=9606 GN=PI4KA PE=1 SV=4"	"3"	"4"	"8"	"4"	"2102"	"236.7"	"7.06"	"1583.58"	"9.50"	"4"	"2"	"other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"kinase activity;other molecular function"	"Pf00454, Pf00613, Pf19274"	"5297"	"ENSG00000241973"	"PI4KA"	"hsa:5297; P42356; Q7Z625; Q9UPG2"	"Ectoderm differentiation; 22q11.2 copy number variation syndrome"	"Synthesis of PIPs at the Golgi membrane; Synthesis of PIPs at the ER membrane"	"4"	"0"	"109.6"	"114.8"	"137.3"	"118.7"	"138.4"	"129.3"	"158.0"	"208.5"	"465.4"	"772.6"	"1185.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55884"	"Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3"	"5"	"3"	"5"	"3"	"814"	"92.4"	"5.00"	"758.31"	"9.48"	"2"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08662"	"8662"	"ENSG00000106263"	"EIF3B"	"A4D208; hsa:8662; P55884; Q2NL77; Q9UMF9"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"8"	"0"	"101.8"	"75.0"	"112.3"	"89.9"	"107.6"	"93.0"	"125.8"	"134.7"	"182.7"	"366.8"	"738.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61088"	"Ubiquitin-conjugating enzyme E2 N OS=Homo sapiens OX=9606 GN=UBE2N PE=1 SV=1"	"26"	"2"	"3"	"2"	"152"	"17.1"	"6.57"	"439.48"	"9.48"	"1"	"2"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00179"	"7334"	"ENSG00000177889"	"UBE2N"	"hsa:7334; P61088; Q16781; Q53Y81"	"IL-1 signaling pathway; Interleukin-1 induced activation of NF-kB; MYD88 distinct input-output pathway; Prader-Willi and Angelman syndrome; 3q29 copy number variation syndrome"	"E3 ubiquitin ligases ubiquitinate target proteins; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; Nonhomologous End-Joining (NHEJ); FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; CLEC7A (Dectin-1) signaling; Aggrephagy; ISG15 antiviral mechanism; SARS-CoV-2 activates/modulates innate and adaptive immune responses; IKK complex recruitment mediated by RIP1; JNK (c-Jun kinases) phosphorylation and  activation mediated by activated human TAK1; NOD1/2 Signaling Pathway; TICAM1, RIP1-mediated IKK complex recruitment; TAK1-dependent IKK and NF-kappa-B activation  ; IRAK1 recruits IKK complex; IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation; activated TAK1 mediates p38 MAPK activation; Formation of Incision Complex in GG-NER; TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling"	"28"	"0"	"6.1"	"10.9"	"10.4"	"8.6"	"7.1"	"9.7"	"11.4"	"11.1"	"27.6"	"201.0"	"775.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P00374"	"Dihydrofolate reductase OS=Homo sapiens OX=9606 GN=DHFR PE=1 SV=2"	"26"	"4"	"6"	"4"	"187"	"21.4"	"7.42"	"1145.19"	"9.42"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00186"	"1719"	"ENSG00000228716"	"DHFR"	"B4DDD2; hsa:1719; P00374; Q14130; Q6IRW8"	"Fluoropyrimidine activity; Folate metabolism; One-carbon metabolism; Retinoblastoma gene in cancer; Trans-sulfuration, one-carbon metabolism and related pathways; Ethanol effects on histone modifications"	"G1/S-Specific Transcription; Metabolism of folate and pterines; Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"	"9"	"0"	"152.6"	"140.9"	"168.8"	"141.2"	"184.9"	"185.2"	"205.2"	"312.0"	"719.1"	"1624.2"	"2731.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11532"	"Dystrophin OS=Homo sapiens OX=9606 GN=DMD PE=1 SV=3"	"1"	"3"	"5"	"1"	"3685"	"426.5"	"5.88"	"1076.55"	"9.40"	"3"	"2"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00397, Pf00435, Pf00569, Pf09068, Pf09069"	"1756"	"ENSG00000198947"	"DMD"	"A1L0U9; E7EQR9; E7EQS5; E7ESB2; E9PDN1; E9PDN5; F5GZY3; F8VX32; hsa:1756; P11532; Q02295; Q14169; Q14170; Q5JYU0; Q6NSJ9; Q7KZ48; Q8N754; Q9UCW3; Q9UCW4"	"Arrhythmogenic right ventricular cardiomyopathy; Ectoderm differentiation; Striated muscle contraction pathway; Acute viral myocarditis; Disturbed pathways in Duchenne Muscular Dystrophy; 13q12.12 copy number variation"	"Non-integrin membrane-ECM interactions; Striated Muscle Contraction"	"8"	"0"	"48.9"	"53.0"	"41.7"	"35.6"	"50.9"	"40.0"	"54.5"	"73.4"	"117.6"	"146.1"	"146.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11413"	"Glucose-6-phosphate 1-dehydrogenase OS=Homo sapiens OX=9606 GN=G6PD PE=1 SV=4"	"12"	"4"	"5"	"4"	"515"	"59.2"	"6.84"	"918.36"	"9.40"	"2"	"3"	"other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00479, Pf02781"	"2539"	"ENSG00000160211"	"G6PD"	"D3DWX9; hsa:2539; P11413; Q16000; Q16765; Q8IU70; Q8IU88; Q8IUA6; Q96PQ2"	"Glutathione metabolism; Pentose phosphate metabolism; Cori cycle; Vitamin D receptor pathway; Nuclear receptors meta-pathway; NRF2 pathway; ATM signaling in development and disease ; Metabolic reprogramming in colon cancer; Vitamin D-sensitive calcium signaling in depression; Pentose phosphate pathway in senescent cells; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Glycolysis in senescence; Sulfation biotransformation reaction"	"TP53 Regulates Metabolic Genes; NFE2L2 regulates pentose phosphate pathway genes; Pentose phosphate pathway"	"16"	"0"	"126.0"	"127.2"	"147.0"	"125.4"	"128.5"	"140.2"	"165.0"	"222.7"	"444.9"	"985.1"	"1845.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75534"	"Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2"	"4"	"4"	"6"	"4"	"798"	"88.8"	"6.25"	"1035.19"	"9.40"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"nucleic acid binding activity"	"Pf00313, Pf12901"	"7812"	"ENSG00000009307"	"CSDE1"	"A8K281; E9PGZ0; G5E9Q2; hsa:7812; O75534; O94961; Q5TF04; Q5TF05; Q68DF1; Q68DI9; Q9Y2S4"	""	""	"0"	"0"	"260.3"	"252.4"	"306.5"	"271.2"	"275.4"	"272.7"	"351.7"	"463.0"	"769.3"	"1712.1"	"3518.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NWH9"	"SAFB-like transcription modulator OS=Homo sapiens OX=9606 GN=SLTM PE=1 SV=2"	"3"	"3"	"6"	"3"	"1034"	"117.1"	"7.87"	"1148.39"	"9.40"	"3"	"3"	"other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf02037"	"79811"	"ENSG00000137776"	"SLTM"	"A8K5V8; B2RTX3; hsa:79811; Q2VPK7; Q52MB3; Q658J7; Q6ZNF2; Q86TK6; Q9H7C3; Q9H8U9; Q9NWH9"	""	""	"0"	"0"	"268.9"	"252.6"	"276.5"	"227.6"	"248.8"	"262.8"	"299.5"	"322.1"	"408.9"	"615.7"	"1052.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P43686"	"26S proteasome regulatory subunit 6B OS=Homo sapiens OX=9606 GN=PSMC4 PE=1 SV=2"	"7"	"2"	"3"	"2"	"418"	"47.3"	"5.21"	"610.90"	"9.38"	"1"	"2"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf16450, Pf17862"	"5704"	"ENSG00000013275; ENSG00000281221"	"PSMC4"	"hsa:5704; P43686; Q96FV5; Q9UBM3; Q9UEX3"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Ciliary landscape; Alzheimer's disease"	"Neddylation; KEAP1-NFE2L2 pathway; Regulation of RAS by GAPs; Regulation of ornithine decarboxylase (ODC); Regulation of expression of SLITs and ROBOs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Interleukin-1 signaling; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"64"	"0"	"64.2"	"71.2"	"80.7"	"65.9"	"80.9"	"81.9"	"99.3"	"115.9"	"196.2"	"371.0"	"706.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22570"	"NADPH:adrenodoxin oxidoreductase, mitochondrial OS=Homo sapiens OX=9606 GN=FDXR PE=1 SV=3"	"11"	"3"	"4"	"3"	"491"	"53.8"	"8.44"	"270.44"	"9.38"	"1"	"3"	"other metabolic processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf07992"	"2232"	"ENSG00000161513"	"FDXR"	"B4DDI7; B4DHX5; B4DQQ4; B4DX24; B7Z7G2; E7EQC1; hsa:2232; P22570; Q13716; Q4PJI0; Q9BU12"	"Iron-sulfur cluster biogenesis"	"Endogenous sterols; Pregnenolone biosynthesis; Defective CYP11A1 causes AICSR; Electron transport from NADPH to Ferredoxin"	"5"	"0"	"57.9"	"50.2"	"73.7"	"57.4"	"74.0"	"64.3"	"72.9"	"99.4"	"339.8"	"792.1"	"1073.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IUF8"	"Ribosomal oxygenase 2 OS=Homo sapiens OX=9606 GN=RIOX2 PE=1 SV=1"	"6"	"1"	"2"	"1"	"465"	"52.8"	"6.70"	""	"9.37"	""	"1"	"cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf08007, Pf20514"	"84864"	"ENSG00000170854"	"RIOX2"	"D3DN35; hsa:84864; Q6AHW4; Q6SKS0; Q8IU69; Q8IUF6; Q8IUF7; Q8IUF8; Q96C17; Q96KB0"	""	"HDMs demethylate histones"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H2K8"	"Serine/threonine-protein kinase TAO3 OS=Homo sapiens OX=9606 GN=TAOK3 PE=1 SV=2"	"5"	"4"	"7"	"3"	"898"	"105.3"	"7.30"	"1461.05"	"9.34"	"4"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069"	"51347"	"ENSG00000135090"	"TAOK3"	"hsa:51347; Q658N1; Q8IUM4; Q9H2K8; Q9HC79; Q9NZM9; Q9UHG7"	"MAPK signaling pathway"	"RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle"	"4"	"0"	"66.2"	"50.9"	"68.0"	"57.8"	"74.2"	"69.4"	"116.3"	"232.6"	"378.6"	"370.0"	"405.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y295"	"Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1"	"10"	"3"	"5"	"3"	"367"	"40.5"	"8.90"	"705.03"	"9.32"	"2"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01926, Pf02824, Pf16897"	"4733"	"ENSG00000185721"	"DRG1"	"B2RDS8; hsa:4733; Q6FGP8; Q8WW69; Q9UGF2; Q9Y295"	""	""	"0"	"0"	"144.6"	"141.0"	"172.0"	"131.6"	"156.2"	"149.6"	"171.9"	"229.2"	"349.0"	"723.7"	"779.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P32322"	"Pyrroline-5-carboxylate reductase 1, mitochondrial OS=Homo sapiens OX=9606 GN=PYCR1 PE=1 SV=2"	"11"	"3"	"6"	"2"	"319"	"33.3"	"7.61"	"937.46"	"9.31"	"3"	"3"	"other metabolic processes;stress response;other biological processes"	"mitochondrion"	"other molecular function"	"Pf03807, Pf14748"	"5831"	"ENSG00000183010"	"PYCR1"	"A6NFM2; B4DMU0; hsa:5831; P32322; Q6FHI4; Q96DI6; Q9HBQ4"	"Amino acid metabolism; Metabolic reprogramming in colon cancer"	"Glutamate and glutamine metabolism"	"3"	"0"	"71.4"	"59.7"	"74.8"	"67.0"	"83.1"	"65.1"	"98.1"	"99.8"	"187.1"	"300.6"	"391.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NVM9"	"Integrator complex subunit 13 OS=Homo sapiens OX=9606 GN=INTS13 PE=1 SV=2"	"8"	"4"	"5"	"4"	"706"	"80.2"	"6.70"	"761.09"	"9.30"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf10221"	"55726"	"ENSG00000064102"	"INTS13"	"B4DNK1; hsa:55726; Q86WE2; Q96HM2; Q9BTX2; Q9NTB6; Q9NVM5; Q9NVM9"	"1p36 copy number variation syndrome"	"RNA polymerase II transcribes snRNA genes"	"2"	"0"	"125.8"	"106.5"	"134.6"	"113.7"	"134.4"	"136.0"	"164.6"	"194.8"	"387.2"	"985.0"	"1459.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BTT0"	"Acidic leucine-rich nuclear phosphoprotein 32 family member E OS=Homo sapiens OX=9606 GN=ANP32E PE=1 SV=1"	"11"	"2"	"4"	"2"	"268"	"30.7"	"3.85"	"1018.28"	"9.28"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf14580"	"81611"	"ENSG00000143401"	"ANP32E"	"B4E0I6; E9PEA6; hsa:81611; Q5TB18; Q5TB20; Q8N1S4; Q8WWW9; Q9BTT0"	""	""	"0"	"0"	"92.7"	"85.3"	"104.2"	"86.6"	"105.4"	"98.9"	"122.3"	"183.9"	"407.9"	"719.5"	"1003.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14684"	"Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3"	"6"	"4"	"7"	"4"	"758"	"84.4"	"9.76"	"1410.56"	"9.27"	"4"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf05997"	"23076"	"ENSG00000160208"	"RRP1B"	"hsa:23076; Q14684; Q8TBZ4"	""	""	"0"	"0"	"294.3"	"251.6"	"298.2"	"262.1"	"294.4"	"270.7"	"369.5"	"447.1"	"782.3"	"1258.5"	"1577.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13409"	"Cytoplasmic dynein 1 intermediate chain 2 OS=Homo sapiens OX=9606 GN=DYNC1I2 PE=1 SV=3"	"4"	"2"	"6"	"2"	"638"	"71.4"	"5.20"	"987.05"	"9.27"	"2"	"2"	"transport;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400, Pf11540"	"1781"	"ENSG00000077380"	"DYNC1I2"	"B7ZA04; D3DPD4; D3DPD5; D3DPD6; hsa:1781; Q13409; Q32LY9; Q53S84; Q5BJF8; Q7Z4X1; Q96NG7; Q96S87; Q9BXZ5; Q9NT58"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein"	"MHC class II antigen presentation; Separation of Sister Chromatids; Aggrephagy; Regulation of PLK1 Activity at G2/M Transition; Resolution of Sister Chromatid Cohesion; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Recruitment of NuMA to mitotic centrosomes; RHO GTPases Activate Formins; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; HCMV Early Events; EML4 and NUDC in mitotic spindle formation; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"21"	"0"	"145.8"	"128.6"	"154.7"	"136.4"	"157.3"	"167.3"	"183.6"	"188.4"	"304.3"	"662.9"	"1148.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N1G2"	"Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 OS=Homo sapiens OX=9606 GN=CMTR1 PE=1 SV=1"	"5"	"4"	"4"	"4"	"835"	"95.3"	"7.05"	"239.03"	"9.25"	"1"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01585, Pf01728"	"23070"	"ENSG00000137200"	"CMTR1"	"A8K949; hsa:23070; Q14670; Q8N1G2; Q96FJ9"	""	""	"0"	"0"	"101.4"	"93.6"	"100.6"	"92.6"	"91.0"	"96.1"	"110.2"	"150.5"	"585.0"	"1239.7"	"1436.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15436"	"Protein transport protein Sec23A OS=Homo sapiens OX=9606 GN=SEC23A PE=1 SV=2"	"5"	"2"	"4"	"2"	"765"	"86.1"	"7.08"	"1014.90"	"9.23"	"1"	"2"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00626, Pf04810, Pf04811, Pf04815, Pf08033"	"10484"	"ENSG00000100934"	"SEC23A"	"B2R5P4; B3KXI2; hsa:10484; Q15436; Q8NE16"	"Sterol regulatory element-binding proteins (SREBP) signaling"	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC; SARS-CoV-2 activates/modulates innate and adaptive immune responses; MHC class II antigen presentation; COPII-mediated vesicle transport; Cargo concentration in the ER; Regulation of cholesterol biosynthesis by SREBP (SREBF)"	"7"	"0"	"119.4"	"93.4"	"136.1"	"106.1"	"125.8"	"112.0"	"129.6"	"153.6"	"230.8"	"435.0"	"702.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TEW0"	"Partitioning defective 3 homolog OS=Homo sapiens OX=9606 GN=PARD3 PE=1 SV=2"	"3"	"2"	"2"	"2"	"1356"	"151.3"	"7.68"	""	"9.23"	""	"2"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00595, Pf12053"	"56288"	"ENSG00000148498"	"PARD3"	"F5H5T0; hsa:56288; Q5T2U1; Q5VUA2; Q5VUA3; Q5VWV0; Q5VWV1; Q5VWV3; Q5VWV4; Q5VWV5; Q6IQ47; Q8TCZ9; Q8TEW0; Q8TEW1; Q8TEW2; Q8TEW3; Q96K28; Q96RM6; Q96RM7; Q9BY57; Q9BY58; Q9HC48; Q9NWL4; Q9NYE6"	"Chemokine signaling pathway; Complement system in neuronal development and plasticity"	"Tight junction interactions; TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"	"4"	"0"	"47.2"	"51.1"	"42.0"	"40.4"	"45.6"	"50.2"	"83.0"	"156.4"	"249.3"	"438.5"	"638.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14854"	"Cytochrome c oxidase subunit 6B1 OS=Homo sapiens OX=9606 GN=COX6B1 PE=1 SV=2"	"49"	"2"	"3"	"2"	"86"	"10.2"	"7.05"	"311.81"	"9.21"	"1"	"2"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf02297"	"1340"	"ENSG00000126267"	"COX6B1"	"B2R5C9; hsa:1340; P14854; Q6IBL4"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex IV assembly; 5q35 copy number variation"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"7"	"0"	"48.1"	"54.3"	"52.5"	"42.3"	"44.4"	"23.0"	"54.4"	"114.4"	"105.9"	"204.8"	"325.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43663"	"Protein regulator of cytokinesis 1 OS=Homo sapiens OX=9606 GN=PRC1 PE=1 SV=2"	"8"	"4"	"6"	"3"	"620"	"71.6"	"6.68"	"1485.10"	"9.18"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03999"	"9055"	"ENSG00000198901"	"PRC1"	"A6NC44; B4DLR1; H9KV59; hsa:9055; O43663; Q9BSB6"	""	"RHO GTPases activate CIT"	"1"	"0"	"215.9"	"194.6"	"194.4"	"175.8"	"203.9"	"207.3"	"245.3"	"339.6"	"656.7"	"955.8"	"1149.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95819"	"Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens OX=9606 GN=MAP4K4 PE=1 SV=2"	"3"	"3"	"6"	"3"	"1239"	"142.0"	"7.46"	"805.77"	"9.16"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"other cell component"	"cytoskeletal activity;kinase activity;other molecular function"	"Pf00069, Pf00780"	"9448"	"ENSG00000071054"	"MAP4K4"	"E7ESS2; hsa:9448; O75172; O95819; Q9NST7"	"MAPK signaling pathway; Angiopoietin-like protein 8 regulatory pathway; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-YAP signaling; Insulin signaling; Pleural mesothelioma"	"Oxidative Stress Induced Senescence"	"7"	"0"	"114.4"	"115.7"	"120.8"	"100.4"	"114.6"	"114.3"	"179.1"	"268.9"	"431.1"	"416.7"	"387.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75874"	"Isocitrate dehydrogenase [NADP] cytoplasmic OS=Homo sapiens OX=9606 GN=IDH1 PE=1 SV=2"	"7"	"3"	"6"	"3"	"414"	"46.6"	"7.01"	"805.52"	"9.15"	"3"	"3"	"other metabolic processes;stress response;developmental processes;other biological processes"	"non-structural extracellular;cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00180"	"3417"	"ENSG00000138413"	"IDH1"	"hsa:3417; O75874; Q567U4; Q6FHQ6; Q7Z3V0; Q93090; Q9NTJ9; Q9UKW8"	"Glutathione metabolism; TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism"	"Peroxisomal protein import; Neutrophil degranulation; Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate; NADPH regeneration; NFE2L2 regulating TCA cycle genes"	"8"	"0"	"119.6"	"118.7"	"155.1"	"121.6"	"130.5"	"137.5"	"158.6"	"193.3"	"300.4"	"772.8"	"1422.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61586"	"Transforming protein RhoA OS=Homo sapiens OX=9606 GN=RHOA PE=1 SV=1"	"14"	"2"	"4"	"2"	"193"	"21.8"	"6.10"	"935.52"	"9.14"	"2"	"2"	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00071"	"387"	"ENSG00000067560"	"RHOA"	"hsa:387; P06749; P61586; Q53HM4; Q5U024; Q9UDJ0; Q9UEJ4"	"Androgen receptor signaling pathway; Physiological and pathological hypertrophy of the heart; MicroRNAs in cardiomyocyte hypertrophy; Leptin signaling pathway; Pathogenic Escherichia coli infection; AGE/RAGE pathway; Corticotropin-releasing hormone signaling pathway; Spinal cord injury; Alpha 6 beta 4 signaling pathway; Focal adhesion; G protein signaling pathways; Wnt signaling pathway; Hypothetical craniofacial development pathway; Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; Wnt signaling pathway and pluripotency; Fibrin complement receptor 3 signaling pathway; Wnt signaling in kidney disease; Chromosomal and microsatellite instability in colorectal cancer ; Ebola virus infection in host; Ras signaling; Pancreatic adenocarcinoma pathway; Wnt signaling; Envelope proteins and their potential roles in EDMD physiopathology; Hippo signaling regulation pathways; Leukocyte-intrinsic Hippo pathway functions; Neural crest cell migration during development; Neural crest cell migration in cancer; Joubert syndrome; Gastrin signaling pathway; Netrin-UNC5B signaling pathway; mBDNF and proBDNF regulation of GABA neurotransmission; MAP3K1 role in promoting and blocking gonadal determination; Airway smooth muscle cell contraction; RAS and bradykinin pathways in COVID-19; Regulation of actin cytoskeleton; GDNF signaling; PtdIns(4,5)P2 in cytokinesis pathway; 2q11.2 copy number variation syndrome; 2q21.1 copy number variation syndrome; G13 signaling pathway; 13q12.12 copy number variation; DNA damage response (only ATM dependent); Serotonin HTR1 group and FOS pathway"	"Neutrophil degranulation; RHOC GTPase cycle; RHOA GTPase cycle; G alpha (12/13) signalling events; RHO GTPases Activate Formins; EPHB-mediated forward signaling; GPVI-mediated activation cascade; PI3K/AKT activation; VEGFA-VEGFR2 Pathway; ERBB2 Regulates Cell Motility; RHO GTPases activate CIT; G beta:gamma signalling through PI3Kgamma; PCP/CE pathway; RHO GTPases Activate Rhotekin and Rhophilins; EPHA-mediated growth cone collapse; Sema4D induced cell migration and growth-cone collapse; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; Sema4D mediated inhibition of cell attachment and migration; Ovarian tumor domain proteases; SLIT2:ROBO1 increases RHOA activity; PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases; TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition); Axonal growth stimulation; Axonal growth inhibition (RHOA activation); RHO GTPases activate KTN1"	"70"	"0"	"71.2"	"58.1"	"101.9"	"94.3"	"85.3"	"55.3"	"88.5"	"109.2"	"175.8"	"271.7"	"374.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NBT2"	"Kinetochore protein Spc24 OS=Homo sapiens OX=9606 GN=SPC24 PE=1 SV=2"	"14"	"1"	"1"	"1"	"197"	"22.5"	"4.70"	""	"9.11"	""	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"24.1"	"25.3"	"27.2"	"20.5"	"31.0"	"28.4"	"32.0"	"34.0"	"57.6"	"83.6"	"102.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94913"	"Pre-mRNA cleavage complex 2 protein Pcf11 OS=Homo sapiens OX=9606 GN=PCF11 PE=1 SV=3"	"2"	"3"	"6"	"3"	"1555"	"172.9"	"8.48"	"835.97"	"9.11"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04818"	"51585"	"ENSG00000165494"	"PCF11"	"A6H8W7; hsa:51585; O43671; O94913; Q6P0X8"	""	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; RNA polymerase II transcribes snRNA genes; Processing of Intronless Pre-mRNAs"	"5"	"0"	"165.2"	"137.3"	"151.7"	"143.7"	"169.8"	"169.8"	"193.3"	"235.9"	"397.7"	"635.7"	"793.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBC2"	"Epidermal growth factor receptor substrate 15-like 1 OS=Homo sapiens OX=9606 GN=EPS15L1 PE=1 SV=1"	"5"	"3"	"5"	"3"	"864"	"94.2"	"5.11"	"626.38"	"9.10"	"2"	"3"	"transport"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf12763"	"58513"	"ENSG00000127527"	"EPS15L1"	"A2RRF3; A5PL29; B4DKA3; hsa:58513; Q9UBC2"	"EGF/EGFR signaling pathway"	"Cargo recognition for clathrin-mediated endocytosis; EGFR downregulation"	"4"	"0"	"13.6"	"20.9"	"17.2"	"16.3"	"16.4"	"21.2"	"20.3"	"33.7"	"46.7"	"70.6"	"91.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NX24"	"H/ACA ribonucleoprotein complex subunit 2 OS=Homo sapiens OX=9606 GN=NHP2 PE=1 SV=1"	"19"	"2"	"4"	"2"	"153"	"17.2"	"8.22"	"1073.65"	"9.09"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf01248"	"55651"	"ENSG00000145912"	"NHP2"	"A6NKY8; hsa:55651; Q9NX24; Q9P095"	""	"rRNA modification in the nucleus and cytosol; Telomere Extension By Telomerase"	"2"	"0"	"246.2"	"189.7"	"233.1"	"221.2"	"236.3"	"231.1"	"259.9"	"345.2"	"834.4"	"1447.8"	"2082.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96RP9"	"Elongation factor G, mitochondrial OS=Homo sapiens OX=9606 GN=GFM1 PE=1 SV=2"	"3"	"2"	"5"	"2"	"751"	"83.4"	"7.01"	"689.73"	"9.09"	"2"	"2"	"protein metabolism;other metabolic processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf00679, Pf03144, Pf03764, Pf14492"	"85476"	"ENSG00000168827"	"GFM1"	"A6NCI9; B2RCB9; B3KRW1; hsa:85476; Q6GTN2; Q96RP9; Q96T39"	""	"Mitochondrial translation elongation"	"1"	"0"	"61.8"	"54.0"	"68.2"	"53.8"	"69.0"	"65.0"	"83.9"	"99.1"	"305.3"	"1072.0"	"1725.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HC52"	"Chromobox protein homolog 8 OS=Homo sapiens OX=9606 GN=CBX8 PE=1 SV=3"	"8"	"2"	"4"	"2"	"389"	"43.4"	"9.91"	"808.19"	"9.05"	"2"	"2"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00385, Pf17218"	"57332"	"ENSG00000141570"	"CBX8"	"hsa:57332; Q96H39; Q9HC52; Q9NR07"	""	"SUMOylation of DNA damage response and repair proteins; Regulation of PTEN gene transcription; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Oxidative Stress Induced Senescence; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins"	"8"	"0"	"84.3"	"87.1"	"91.0"	"73.5"	"83.7"	"76.0"	"90.7"	"131.9"	"152.6"	"301.0"	"452.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5EBL8"	"PDZ domain-containing protein 11 OS=Homo sapiens OX=9606 GN=PDZD11 PE=1 SV=2"	"30"	"3"	"4"	"2"	"140"	"16.1"	"7.21"	"600.54"	"9.05"	"2"	"2"	"cell-cell signaling;cell organization and biogenesis;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;other cell component"	""	"Pf00595"	"51248"	"ENSG00000120509"	"PDZD11"	"D3DVU3; hsa:51248; Q5EBL8; Q6UWE1; Q9P0Q1"	""	"Ion transport by P-type ATPases; Ion influx/efflux at host-pathogen interface; Transport of vitamins, nucleosides, and related molecules; Biotin transport and metabolism; Vitamin B5 (pantothenate) metabolism"	"5"	"0"	"61.1"	"69.9"	"74.0"	"64.2"	"77.9"	"86.2"	"86.5"	"107.4"	"234.9"	"404.4"	"594.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NVX2"	"Notchless protein homolog 1 OS=Homo sapiens OX=9606 GN=NLE1 PE=1 SV=4"	"7"	"2"	"3"	"2"	"485"	"53.3"	"7.34"	"327.05"	"9.03"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"nucleus"	""	"Pf00400, Pf08154"	"54475"	"ENSG00000073536"	"NLE1"	"hsa:54475; O60868; Q59GJ8; Q9BU54; Q9NVX2"	"17q12 copy number variation syndrome"	""	"1"	"0"	"20.9"	"25.2"	"27.8"	"17.0"	"21.7"	"23.0"	"26.3"	"40.2"	"70.5"	"155.4"	"232.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30085"	"UMP-CMP kinase OS=Homo sapiens OX=9606 GN=CMPK1 PE=1 SV=3"	"10"	"2"	"5"	"2"	"196"	"22.2"	"5.57"	"636.92"	"9.00"	"2"	"2"	"other metabolic processes"	"cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00406"	"51727"	"ENSG00000162368"	"CMPK1"	"B2R6S5; B4DPU7; E9PGI8; hsa:51727; P30085; Q53GB7; Q5SVZ0; Q96C07; Q9UBQ8; Q9UIA2"	"Pyrimidine metabolism"	"Interconversion of nucleotide di- and triphosphates"	"2"	"0"	"98.8"	"97.3"	"110.3"	"111.0"	"102.1"	"95.1"	"129.4"	"136.4"	"220.0"	"536.5"	"1732.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P2K3"	"REST corepressor 3 OS=Homo sapiens OX=9606 GN=RCOR3 PE=1 SV=2"	"7"	"2"	"4"	"1"	"495"	"55.5"	"8.27"	"892.98"	"8.99"	"2"	"2"	"other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00249, Pf01448"	"55758"	"ENSG00000117625"	"RCOR3"	"B3KYA2; B4DYY7; hsa:55758; Q5VT47; Q7L9I5; Q8N5U3; Q9NV83; Q9P2K3"	""	""	"0"	"0"	"21.3"	"18.9"	"29.5"	"23.0"	"27.6"	"23.5"	"24.8"	"29.4"	"51.9"	"85.6"	"87.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51970"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 OS=Homo sapiens OX=9606 GN=NDUFA8 PE=1 SV=3"	"26"	"4"	"7"	"4"	"172"	"20.1"	"7.65"	"1471.33"	"8.99"	"4"	"3"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf06747"	"4702"	"ENSG00000119421"	"NDUFA8"	"B1AM93; hsa:4702; P51970; Q9Y6N0"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"659.4"	"657.1"	"487.9"	"500.7"	"644.8"	"544.5"	"696.3"	"929.4"	"1642.4"	"3864.1"	"5361.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75909"	"Cyclin-K OS=Homo sapiens OX=9606 GN=CCNK PE=1 SV=2"	"6"	"2"	"4"	"2"	"580"	"64.2"	"8.41"	"918.98"	"8.99"	"2"	"2"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00134"	"8812"	"ENSG00000090061"	"CCNK"	"hsa:8812; O75909; Q59FT6; Q86U16; Q96B63; Q9NNY9"	"Male infertility"	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes"	"10"	"0"	"51.5"	"39.0"	"54.8"	"51.7"	"49.6"	"54.1"	"56.8"	"72.8"	"173.4"	"366.1"	"606.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N6N3"	"UPF0690 protein C1orf52 OS=Homo sapiens OX=9606 GN=C1orf52 PE=1 SV=1"	"13"	"2"	"4"	"2"	"182"	"20.6"	"5.21"	"727.28"	"8.97"	"2"	"2"	""	"nucleus"	""	"Pf15559"	"148423"	"ENSG00000162642"	"C1orf52"	"B3KX89; hsa:148423; Q8N6N3; Q8TDK5; Q8TDK6"	""	""	"0"	"0"	"94.3"	"84.9"	"90.9"	"96.9"	"103.3"	"96.2"	"121.9"	"133.2"	"156.4"	"230.9"	"323.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NQ50"	"39S ribosomal protein L40, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL40 PE=1 SV=1"	"16"	"2"	"4"	"2"	"206"	"24.5"	"9.63"	"1155.87"	"8.96"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	""	"Pf09812"	"64976"	"ENSG00000185608"	"MRPL40"	"B3KVZ7; hsa:64976; O95134; Q9NQ50"	"22q11.2 copy number variation syndrome"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"4"	"0"	"78.5"	"83.4"	"80.9"	"78.5"	"73.6"	"89.4"	"105.0"	"113.2"	"183.6"	"256.7"	"340.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z478"	"ATP-dependent RNA helicase DHX29 OS=Homo sapiens OX=9606 GN=DHX29 PE=1 SV=2"	"7"	"6"	"7"	"6"	"1369"	"155.1"	"8.09"	"1439.04"	"8.94"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"54505"	"ENSG00000067248"	"DHX29"	"hsa:54505; O75549; Q63HN0; Q63HN3; Q7Z478; Q8IWW2; Q8N3A1; Q9UMH2"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"108.1"	"102.5"	"118.9"	"89.6"	"107.3"	"110.5"	"128.5"	"122.9"	"187.7"	"510.8"	"701.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61221"	"ATP-binding cassette sub-family E member 1 OS=Homo sapiens OX=9606 GN=ABCE1 PE=1 SV=1"	"5"	"3"	"6"	"3"	"599"	"67.3"	"8.34"	"1231.99"	"8.94"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;mitochondrion;translational apparatus;other cell component"	"enzyme regulator activity;translation activity;other molecular function"	"Pf00005, Pf00037, Pf04068"	"6059"	"ENSG00000164163"	"ABCE1"	"hsa:6059; O88793; P61221; Q13181; Q13864; Q6NR76; Q96AL0; Q96B10; Q99K66"	""	"OAS antiviral response; Interferon alpha/beta signaling"	"2"	"0"	"261.4"	"274.6"	"342.0"	"283.0"	"334.6"	"315.9"	"412.6"	"653.4"	"1334.3"	"1957.1"	"2161.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96FJ2"	"Dynein light chain 2, cytoplasmic OS=Homo sapiens OX=9606 GN=DYNLL2 PE=1 SV=1"	"33"	"2"	"3"	"2"	"89"	"10.3"	"7.37"	"287.46"	"8.92"	"1"	"2"	"other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf01221"	"140735"	"ENSG00000264364"	"DYNLL2"	"B2R5B4; hsa:140735; Q96FJ2"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein; 3q29 copy number variation syndrome"	"MHC class II antigen presentation; HCMV Early Events; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Intraflagellar transport; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Aggrephagy; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Macroautophagy; Activation of BMF and translocation to mitochondria"	"18"	"0"	"174.4"	"161.5"	"187.8"	"186.3"	"256.3"	"228.1"	"244.1"	"237.3"	"338.0"	"521.6"	"718.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P21912"	"Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHB PE=1 SV=3"	"11"	"4"	"7"	"4"	"280"	"31.6"	"8.76"	"1127.55"	"8.92"	"4"	"3"	"other metabolic processes"	"plasma membrane;other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf13085, Pf13534"	"6390"	"ENSG00000117118"	"SDHB"	"B2R545; hsa:6390; P21912; Q0QEY7; Q9NQ12"	"Electron transport chain: OXPHOS system in mitochondria; Metabolic reprogramming in colon cancer; Nonalcoholic fatty liver disease; Mitochondrial complex II assembly; TCA cycle (aka Krebs or citric acid cycle)"	"Respiratory electron transport; Citric acid cycle (TCA cycle)"	"7"	"0"	"560.4"	"457.9"	"521.4"	"484.9"	"489.1"	"389.5"	"558.4"	"679.6"	"1165.4"	"1965.2"	"2453.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13557"	"Calcium/calmodulin-dependent protein kinase type II subunit delta OS=Homo sapiens OX=9606 GN=CAMK2D PE=1 SV=3"	"4"	"2"	"6"	"2"	"499"	"56.3"	"7.25"	"1166.56"	"8.92"	"2"	"2"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;kinase activity;other molecular function"	"Pf00069, Pf08332"	"817"	"ENSG00000145349"	"CAMK2D"	"A8MVS8; hsa:817; Q13557; Q52PK4; Q59G21; Q8N553; Q9UGH6; Q9UQE9"	"Physiological and pathological hypertrophy of the heart; MicroRNAs in cardiomyocyte hypertrophy; SRF and miRs in smooth muscle differentiation and proliferation; Cardiac hypertrophic response; Myometrial relaxation and contraction pathways; NO/cGMP/PKG mediated neuroprotection; Wnt signaling; Non-genomic actions of 1,25 dihydroxyvitamin D3; Disruption of postsynaptic signaling by CNV; Neuroinflammation and glutamatergic signaling; Disturbed pathways in Duchenne Muscular Dystrophy; Calcium regulation in cardiac cells; ErbB signaling pathway"	"Ion homeostasis; Ion transport by P-type ATPases; Assembly and cell surface presentation of NMDA receptors; Signaling by BRAF and RAF1 fusions; Interferon gamma signaling; RAF activation; Ras activation upon Ca2+ influx through NMDA receptor; Regulation of MECP2 expression and activity; Unblocking of NMDA receptors, glutamate binding and activation; Negative regulation of NMDA receptor-mediated neuronal transmission; Long-term potentiation; Trafficking of AMPA receptors; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; Phase 0 - rapid depolarisation; HSF1-dependent transactivation; CaMK IV-mediated phosphorylation of CREB"	"33"	"0"	"211.7"	"201.2"	"237.8"	"196.7"	"225.1"	"207.4"	"249.3"	"327.1"	"680.0"	"1517.9"	"2091.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92879"	"CUGBP Elav-like family member 1 OS=Homo sapiens OX=9606 GN=CELF1 PE=1 SV=2"	"6"	"3"	"5"	"3"	"486"	"52.0"	"8.46"	"630.81"	"8.91"	"2"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"10658"	"ENSG00000149187"	"CELF1"	"B4E2U5; D3DQS0; F8W940; hsa:10658; Q4LE52; Q92879; Q9NP83; Q9NR06"	"Adipogenesis; mRNA processing"	""	"2"	"0"	"169.3"	"174.5"	"169.3"	"166.6"	"175.7"	"117.5"	"180.4"	"259.7"	"418.5"	"975.0"	"1595.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IUR0"	"Trafficking protein particle complex subunit 5 OS=Homo sapiens OX=9606 GN=TRAPPC5 PE=1 SV=1"	"15"	"2"	"4"	"2"	"188"	"20.8"	"9.66"	"836.74"	"8.89"	"2"	"2"	"cell organization and biogenesis;transport"	"cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf04051"	"126003"	"ENSG00000181029"	"TRAPPC5"	"A8K7I6; hsa:126003; Q8IUR0"	""	"RAB GEFs exchange GTP for GDP on RABs; COPII-mediated vesicle transport"	"2"	"0"	"64.0"	"66.6"	"78.2"	"73.5"	"70.1"	"75.7"	"100.7"	"162.4"	"360.3"	"683.7"	"1019.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBC3"	"DNA (cytosine-5)-methyltransferase 3B OS=Homo sapiens OX=9606 GN=DNMT3B PE=1 SV=1"	"2"	"1"	"4"	"1"	"853"	"95.7"	"8.43"	"638.82"	"8.88"	"1"	"1"	"DNA metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00145, Pf00855, Pf17980"	"1789"	"ENSG00000088305"	"DNMT3B"	"A2A2E2; B4DSM8; B4DSU1; E1P5M6; E1P5M7; E7EN63; E9PBF2; hsa:1789; Q9UBC3; Q9UBD4; Q9UJQ5; Q9UKA6; Q9UNE5; Q9Y5R9; Q9Y5S0"	"One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways; Mesodermal commitment pathway; Hematopoietic stem cell gene regulation by GABP alpha/beta complex; MTHFR deficiency"	"SUMOylation of DNA methylation proteins; NoRC negatively regulates rRNA expression; PRC2 methylates histones and DNA; Defective pyroptosis; DNA methylation"	"10"	"0"	"43.8"	"36.1"	"44.4"	"40.7"	"48.0"	"45.4"	"54.2"	"56.0"	"106.4"	"151.6"	"173.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49411"	"Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2"	"11"	"4"	"7"	"4"	"452"	"49.5"	"7.61"	"1594.40"	"8.86"	"4"	"3"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"413.5"	"405.9"	"408.5"	"378.9"	"421.2"	"439.6"	"497.8"	"548.6"	"800.7"	"1392.7"	"1928.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43427"	"Acidic fibroblast growth factor intracellular-binding protein OS=Homo sapiens OX=9606 GN=FIBP PE=1 SV=3"	"7"	"3"	"6"	"3"	"364"	"41.9"	"6.48"	"897.12"	"8.86"	"3"	"3"	"signal transduction"	"other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf05427"	"9158"	"ENSG00000172500"	"FIBP"	"A8K0J7; hsa:9158; O43427; Q27Q85; Q6IBQ3; Q9HD65"	"Modulators of TCR signaling and T cell activation"	""	"1"	"0"	"46.7"	"40.0"	"58.6"	"45.9"	"55.8"	"112.5"	"203.1"	"398.1"	"878.6"	"1295.1"	"1461.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NS86"	"LanC-like protein 2 OS=Homo sapiens OX=9606 GN=LANCL2 PE=1 SV=1"	"5"	"2"	"2"	"2"	"450"	"50.8"	"7.43"	""	"8.86"	""	"2"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus"	"other molecular function"	"Pf05147"	"55915"	"ENSG00000132434"	"LANCL2"	"B2R8D4; hsa:55915; Q6NSL4; Q8TCQ3; Q9BSR1; Q9NS86"	""	""	"0"	"0"	"37.0"	"37.3"	"47.6"	"35.2"	"45.1"	"37.7"	"49.4"	"67.8"	"170.8"	"495.9"	"772.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P83881"	"60S ribosomal protein L36a OS=Homo sapiens OX=9606 GN=RPL36A PE=1 SV=2"	"29"	"4"	"6"	"4"	"106"	"12.4"	"10.58"	"874.10"	"8.85"	"3"	"3"	"protein metabolism;other metabolic processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;translational apparatus"	"other molecular function"	"Pf00935"	"6173"	"ENSG00000241343"	"RPL36A"	"hsa:6173; P09896; P10661; P83881; Q08ES5; Q5J9I6"	"Cytoplasmic ribosomal proteins"	"GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"579.7"	"531.1"	"515.0"	"500.4"	"552.2"	"512.8"	"645.8"	"841.6"	"1110.8"	"1813.8"	"2905.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00139"	"Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3"	"4"	"3"	"5"	"3"	"706"	"79.9"	"6.68"	"768.55"	"8.85"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225"	"3796"	"ENSG00000068796"	"KIF2A"	"A5YM42; A5YM54; B4DY54; D3DW97; E9PB70; hsa:3796; O00139; Q7Z5I3; Q8N5Q7"	""	"COPI-dependent Golgi-to-ER retrograde traffic; Separation of Sister Chromatids; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Kinesins; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"9"	"0"	"226.0"	"174.9"	"218.8"	"214.5"	"238.8"	"232.1"	"292.9"	"349.6"	"460.8"	"657.6"	"839.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N6H7"	"ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1"	"7"	"4"	"7"	"4"	"521"	"56.7"	"7.99"	"1145.69"	"8.84"	"4"	"3"	"cell organization and biogenesis;transport"	"plasma membrane;other membranes;cytosol;ER/Golgi"	"enzyme regulator activity;other molecular function"	"Pf01412"	"84364"	"ENSG00000149182"	"ARFGAP2"	"B4DX29; B7Z9M7; D3DQQ9; hsa:84364; Q3LIF2; Q8N3I1; Q8N6H7; Q96SX7"	"IL-18 signaling pathway; 5q35 copy number variation"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport; CDC42 GTPase cycle"	"5"	"0"	"445.0"	"361.5"	"466.9"	"397.8"	"446.4"	"478.2"	"560.8"	"658.7"	"1284.5"	"1633.6"	"1941.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00255"	"Menin OS=Homo sapiens OX=9606 GN=MEN1 PE=1 SV=4"	"6"	"3"	"5"	"3"	"615"	"68.0"	"6.55"	"607.55"	"8.83"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05053"	"4221"	"ENSG00000133895"	"MEN1"	"A5HBC6; A5HBC7; A5HBC8; A5HBC9; A5HBD0; A5HBD1; A5HBD2; hsa:4221; O00255; O00632; Q9BUF0; Q9BUK2"	"10q11.21q11.23 copy number variation syndrome"	"RHO GTPases activate IQGAPs; Formation of WDR5-containing histone-modifying complexes; Formation of the beta-catenin:TCF transactivating complex; SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Deactivation of the beta-catenin transactivating complex; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation"	"8"	"0"	"266.9"	"150.9"	"320.1"	"230.5"	"263.9"	"263.4"	"284.6"	"291.5"	"522.3"	"926.2"	"1300.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96HS1"	"Serine/threonine-protein phosphatase PGAM5, mitochondrial OS=Homo sapiens OX=9606 GN=PGAM5 PE=1 SV=2"	"8"	"2"	"4"	"2"	"289"	"32.0"	"8.68"	"886.35"	"8.83"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion"	"enzyme regulator activity;other molecular function"	"Pf00300"	"192111"	"ENSG00000247077"	"PGAM5"	"A9LN06; C9IZY7; hsa:192111; Q96HS1; Q96JB0"	"NRF2-ARE regulation"	""	"1"	"0"	"120.0"	"117.0"	"125.6"	"111.9"	"159.1"	"139.4"	"156.8"	"187.0"	"407.3"	"942.8"	"1496.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6UVY6"	"DBH-like monooxygenase protein 1 OS=Homo sapiens OX=9606 GN=MOXD1 PE=1 SV=1"	"4"	"2"	"4"	"2"	"613"	"69.6"	"6.43"	"779.87"	"8.83"	"2"	"2"	"other metabolic processes"	"non-structural extracellular;other membranes;ER/Golgi"	"other molecular function"	"Pf01082, Pf03351, Pf03712"	"26002"	"ENSG00000079931"	"MOXD1"	"hsa:26002; Q5THU6; Q6UVY6; Q8NC97; Q8WV49; Q9H4M6; Q9Y4U3"	""	""	"0"	"0"	"79.3"	"79.9"	"81.1"	"78.2"	"83.1"	"82.2"	"84.2"	"120.0"	"236.1"	"677.8"	"1262.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q00403"	"Transcription initiation factor IIB OS=Homo sapiens OX=9606 GN=GTF2B PE=1 SV=1"	"12"	"2"	"3"	"2"	"316"	"34.8"	"8.35"	"510.63"	"8.82"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00382, Pf08271"	"2959"	"ENSG00000137947"	"GTF2B"	"A8K1A7; hsa:2959; Q00403; Q5JS30"	"Eukaryotic transcription initiation"	"RNA Polymerase II Pre-transcription Events; RNA polymerase II transcribes snRNA genes; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation"	"10"	"0"	"106.6"	"91.9"	"99.4"	"83.9"	"92.0"	"93.5"	"125.7"	"122.5"	"271.3"	"269.4"	"204.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P01116"	"GTPase KRas OS=Homo sapiens OX=9606 GN=KRAS PE=1 SV=1"	"13"	"2"	"6"	"2"	"189"	"21.6"	"6.77"	"1032.05"	"8.82"	"2"	"2"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00071"	"3845"	"ENSG00000133703"	"KRAS"	"A8K8Z5; B0LPF9; hsa:3845; P01116; P01118; Q96D10"	"IL-5 signaling pathway; Alzheimer's disease and miRNA effects; Glioblastoma signaling pathways; RalA downstream regulated genes; TNF-alpha signaling pathway; Oncostatin M signaling pathway; Aryl hydrocarbon receptor pathway; Bladder cancer; Extracellular vesicle-mediated signaling in recipient cells; RAC1/PAK1/p38/MMP2 pathway; G protein signaling pathways; BDNF-TrkB signaling; MAPK signaling pathway; PI3K-AKT-mTOR signaling pathway and therapeutic opportunities in prostate cancer; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Endometrial cancer; PI3K-Akt signaling pathway; Chromosomal and microsatellite instability in colorectal cancer ; MAPK cascade; Ras signaling; Epithelial to mesenchymal transition in colorectal cancer; Non-small cell lung cancer; Breast cancer pathway; Pancreatic adenocarcinoma pathway; Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells; Thermogenesis; Non-genomic actions of 1,25 dihydroxyvitamin D3; EGF/EGFR signaling pathway; Relationship between inflammation, COX-2 and EGFR; Envelope proteins and their potential roles in EDMD physiopathology; Synaptic signaling pathways associated with autism spectrum disorder; Hippo-Merlin signaling dysregulation; Fragile X syndrome; Gastrin signaling pathway; Hepatitis B infection; Head and neck squamous cell carcinoma; Melanoma; EGFR tyrosine kinase inhibitor resistance; Kisspeptin/kisspeptin receptor system in the ovary; MAPK pathway in congenital thyroid cancer; Regulation of actin cytoskeleton; Alzheimer's disease; Autophagy in pancreatic ductal adenocarcinoma; JAK-STAT signaling in the regulation of Beta-cells; ErbB signaling pathway; DNA damage response (only ATM dependent); Serotonin receptor 2 and ELK-SRF/GATA4 signaling"	"Signaling by CSF3 (G-CSF); Signaling by CSF1 (M-CSF) in myeloid cells; RAS processing; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAS GAP mutants; Signaling by RAS GTPase mutants; RUNX3 regulates p14-ARF"	"57"	"0"	"22.5"	"27.9"	"30.0"	"23.4"	"35.5"	"33.1"	"57.3"	"107.2"	"152.2"	"217.7"	"249.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60941"	"Dystrobrevin beta OS=Homo sapiens OX=9606 GN=DTNB PE=1 SV=1"	"5"	"3"	"6"	"1"	"627"	"71.3"	"7.91"	"1177.97"	"8.81"	"3"	"3"	"cell-cell signaling;developmental processes"	"plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00569, Pf09068, Pf09069"	"1838"	"ENSG00000138101"	"DTNB"	"B7Z733; F5GZG4; G5E9F6; hsa:1838; O43782; O60881; O60941; O75538; Q86VR4; Q96AW0; Q9UE14; Q9UE15; Q9UE16"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15084"	"Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A OS=Homo sapiens OX=9606 GN=ANKRD28 PE=1 SV=5"	"3"	"2"	"4"	"2"	"1053"	"112.9"	"6.25"	"913.13"	"8.80"	"2"	"2"	""	"cytosol;nucleus"	""	"Pf00023, Pf13637"	"23243"	"ENSG00000206560"	"ANKRD28"	"B4DES5; hsa:23243; O15084; Q1WWL4; Q29RW6; Q3B857; Q6ULS0; Q6ZT57"	""	"Telomere Extension By Telomerase; COPII-mediated vesicle transport"	"2"	"0"	"36.3"	"31.8"	"48.5"	"47.1"	"47.6"	"36.0"	"40.7"	"61.8"	"108.2"	"189.0"	"257.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6GYQ0"	"Ral GTPase-activating protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=RALGAPA1 PE=1 SV=1"	"2"	"2"	"4"	"2"	"2036"	"229.7"	"6.19"	"742.73"	"8.79"	"2"	"2"	"other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02145, Pf20412"	"253959"	"ENSG00000174373"	"RALGAPA1"	"A6NMA4; B9EK38; C5NU19; hsa:253959; O94960; Q6GYP9; Q6GYQ0; Q6ZT23; Q86YF3; Q86YF5; Q8ND69"	""	"RHOH GTPase cycle"	"1"	"0"	"17.2"	"21.2"	"26.7"	"19.6"	"22.7"	"19.1"	"39.5"	"80.7"	"188.8"	"312.4"	"348.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H425"	"Uncharacterized protein C1orf198 OS=Homo sapiens OX=9606 GN=C1orf198 PE=1 SV=1"	"7"	"2"	"3"	"2"	"327"	"36.3"	"5.72"	"605.94"	"8.78"	"1"	"2"	""	"cytosol"	""	"Pf15797"	"84886"	"ENSG00000119280"	"C1orf198"	"A8K8R8; B3KTW1; G5EA08; hsa:84886; Q9H425"	""	""	"0"	"0"	"42.4"	"29.5"	"37.8"	"46.1"	"40.1"	"42.7"	"54.2"	"66.3"	"126.1"	"188.0"	"235.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NX55"	"Huntingtin-interacting protein K OS=Homo sapiens OX=9606 GN=HYPK PE=1 SV=2"	"26"	"3"	"7"	"3"	"129"	"14.7"	"4.93"	"2610.77"	"8.78"	"3"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf04419, Pf19026"	"100137436; 101127706; 104002286; 104679625; 105491324; 105549422; 105588143; 108521295; 25764; 713266"	"ENSCATG00000038565; ENSGGOG00000014809; ENSMFAG00000057677; ENSMLEG00000000898; ENSMMUG00000022768; ENSMNEG00000018318; ENSPANG00000018102; ENSPPAG00000034659; ENSPTEG00000009792; ENSPTEG00000019135; ENSPTRG00000038721; ENSRBIG00000028237; ENSRROG00000039445; ENSTGEG00000007663"	"HYPK; LOC113219833"	"A0A024R5Q1; A0A1D5R5K3; A0A2I2YQJ1; A0A2J8NTT0; A0A2K5N035; A0A2K5TR12; A0A2K5XAQ0; A0A2K6AXP0; A0A2K6KBN5; A0A2K6QRU2; A0A2R9B6N1; A0A663DGD1; A0A6D2Y1W8; A0A8C9GZF6; A0A8D2ERJ4; A0A8J8XMG0; A9X1C4; F7GC11; G7MX15; G7PB77; H2Q9B3; hsa:25764; mcc:713266; mleu:105549422; mni:105491324; panu:100137436; ptr:104002286; rbb:108521295; rro:104679625"	""	""	"0"	"0"	"33.6"	"27.9"	"47.4"	"38.3"	"30.9"	"35.9"	"40.3"	"80.9"	"320.6"	"1440.4"	"2130.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30038"	"Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH4A1 PE=1 SV=3"	"5"	"2"	"4"	"2"	"563"	"61.7"	"8.07"	"884.07"	"8.76"	"2"	"2"	"other metabolic processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf00171"	"8659"	"ENSG00000159423"	"ALDH4A1"	"A8K1Q7; B4DGE4; D2D4A3; hsa:8659; P30038; Q16882; Q53HU4; Q5JNV6; Q8IZ38; Q96IF0; Q9UDI6"	"22q11.2 copy number variation syndrome; p53 transcriptional gene network"	"Glyoxylate metabolism and glycine degradation; Proline catabolism"	"4"	"0"	"36.2"	"39.9"	"52.9"	"47.7"	"51.0"	"47.1"	"62.5"	"112.6"	"551.5"	"1287.9"	"1795.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UJ83"	"2-hydroxyacyl-CoA lyase 1 OS=Homo sapiens OX=9606 GN=HACL1 PE=1 SV=2"	"7"	"2"	"3"	"2"	"578"	"63.7"	"7.36"	"569.68"	"8.75"	"1"	"2"	"cell organization and biogenesis;other metabolic processes;transport"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00205, Pf02775, Pf02776"	"26061"	"ENSG00000131373"	"HACL1"	"B4DWI1; B4DXI5; E9PEN4; hsa:26061; Q9BV42; Q9P0A2; Q9UJ83"	""	"Peroxisomal protein import; Alpha-oxidation of phytanate"	"2"	"0"	"71.1"	"54.0"	"82.6"	"61.9"	"88.1"	"66.2"	"111.6"	"195.3"	"525.7"	"724.4"	"975.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P53597"	"Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLG1 PE=1 SV=4"	"9"	"2"	"4"	"2"	"346"	"36.2"	"8.79"	"794.52"	"8.73"	"2"	"2"	"other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf00549, Pf02629"	"8802"	"ENSG00000163541"	"SUCLG1"	"hsa:8802; P53597; Q9BWB0; Q9UNP6"	"Amino acid metabolism; TCA cycle (aka Krebs or citric acid cycle)"	"Citric acid cycle (TCA cycle)"	"3"	"0"	"47.7"	"80.5"	"75.1"	"74.2"	"71.5"	"62.5"	"76.5"	"111.5"	"153.3"	"352.0"	"748.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BRT2"	"Ubiquinol-cytochrome-c reductase complex assembly factor 2 OS=Homo sapiens OX=9606 GN=UQCC2 PE=1 SV=1"	"15"	"2"	"5"	"2"	"126"	"14.9"	"7.37"	"1018.63"	"8.71"	"2"	"1"	"cell organization and biogenesis;other biological processes"	"other membranes;mitochondrion;nucleus"	""	"Pf20180"	"84300"	"ENSG00000137288"	"UQCC2"	"B2R4I0; hsa:84300; Q9BRT2"	"Mitochondrial complex III assembly"	""	"1"	"0"	"187.6"	"156.3"	"181.0"	"160.4"	"214.1"	"195.9"	"237.8"	"429.5"	"858.4"	"1047.1"	"1035.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07237"	"Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3"	"5"	"3"	"6"	"3"	"508"	"57.1"	"4.87"	"924.18"	"8.71"	"3"	"3"	"protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00085, Pf13848"	"5034"	"ENSG00000185624"	"P4HB"	"B2RDQ2; hsa:5034; P07237; P30037; P32079; Q15205; Q6LDE5"	"VEGFA-VEGFR2 signaling; Type I collagen synthesis in the context of osteogenesis imperfecta"	"Hedgehog ligand biogenesis; Collagen biosynthesis and modifying enzymes; Detoxification of Reactive Oxygen Species; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Insulin processing; Interleukin-12 signaling; Interleukin-23 signaling; Chylomicron assembly; VLDL assembly; LDL remodeling"	"13"	"0"	"184.4"	"182.3"	"233.1"	"184.9"	"233.2"	"184.3"	"241.5"	"327.9"	"403.2"	"572.5"	"723.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H9Q2"	"COP9 signalosome complex subunit 7b OS=Homo sapiens OX=9606 GN=COPS7B PE=1 SV=1"	"10"	"2"	"4"	"2"	"264"	"29.6"	"6.15"	"846.78"	"8.70"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf01399, Pf18392"	"64708"	"ENSG00000144524"	"COPS7B"	"hsa:64708; Q53S22; Q5BJG3; Q9H7V6; Q9H9Q2"	"Ciliary landscape"	"Neddylation; Cargo recognition for clathrin-mediated endocytosis; Formation of TC-NER Pre-Incision Complex; DNA Damage Recognition in GG-NER"	"5"	"0"	"53.1"	"50.1"	"58.3"	"46.7"	"60.0"	"58.6"	"91.2"	"116.7"	"220.8"	"489.6"	"797.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09417"	"Dihydropteridine reductase OS=Homo sapiens OX=9606 GN=QDPR PE=1 SV=2"	"11"	"2"	"3"	"2"	"244"	"25.8"	"7.37"	"549.76"	"8.70"	"1"	"2"	"other metabolic processes;developmental processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00106"	"5860"	"ENSG00000151552"	"QDPR"	"A8K158; B3KW71; hsa:5860; P09417; Q53F52; Q9H3M5"	""	"Phenylalanine metabolism"	"1"	"0"	"31.1"	"26.6"	"44.6"	"37.6"	"37.3"	"33.9"	"44.2"	"68.4"	"157.9"	"535.2"	"1002.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14137"	"Ribosome biogenesis protein BOP1 OS=Homo sapiens OX=9606 GN=BOP1 PE=1 SV=2"	"4"	"2"	"4"	"2"	"746"	"83.6"	"6.19"	"794.60"	"8.69"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00400, Pf08145"	"23246"	"ENSG00000261236; ENSG00000285301"	"BOP1"	"hsa:23246; Q14137; Q969Z6; Q96IS8; Q96Q25; Q9BSA7; Q9BVM0"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"66.1"	"71.1"	"69.8"	"60.0"	"67.0"	"59.0"	"84.1"	"83.0"	"138.4"	"280.0"	"339.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NZM3"	"Intersectin-2 OS=Homo sapiens OX=9606 GN=ITSN2 PE=1 SV=3"	"2"	"3"	"5"	"3"	"1697"	"193.3"	"8.12"	"562.89"	"8.67"	"2"	"3"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00018, Pf00168, Pf00621, Pf07653, Pf12763, Pf14604, Pf16652"	"50618"	"ENSG00000198399"	"ITSN2"	"hsa:50618; O95062; Q15812; Q9HAK4; Q9NXE6; Q9NYG0; Q9NZM2; Q9NZM3; Q9ULG4"	""	"Cargo recognition for clathrin-mediated endocytosis; RHOU GTPase cycle"	"3"	"0"	"26.0"	"26.9"	"41.7"	"35.6"	"43.5"	"56.4"	"101.7"	"203.4"	"293.0"	"352.0"	"353.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z406"	"Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2"	"2"	"4"	"4"	"1"	"1995"	"227.7"	"5.60"	"478.52"	"8.67"	"1"	"3"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00063, Pf01576, Pf02736"	"79784"	"ENSG00000105357"	"MYH14"	"B0I1S2; C3TTN4; hsa:79784; Q5CZ75; Q6XYE4; Q76B62; Q7Z406; Q8WV23; Q96I22; Q9BT27; Q9BW35; Q9H882"	""	"EPHA-mediated growth cone collapse; Sema4D induced cell migration and growth-cone collapse; RHO GTPases Activate ROCKs; RHO GTPases activate CIT; RHO GTPases activate PKNs; RHO GTPases activate PAKs"	"6"	"0"	"6.8"	"2.9"	"4.9"	"4.3"	"5.7"	"8.1"	"6.6"	"9.4"	"14.3"	"25.2"	"52.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5T653"	"39S ribosomal protein L2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL2 PE=1 SV=2"	"9"	"2"	"4"	"2"	"305"	"33.3"	"11.30"	"1031.42"	"8.66"	"2"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf00181, Pf03947"	"51069"	"ENSG00000112651"	"MRPL2"	"B2RC56; hsa:51069; Q5T653; Q8WUL1; Q96Q56; Q9Y311"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"37.7"	"28.5"	"36.7"	"24.8"	"28.1"	"28.7"	"38.4"	"45.1"	"55.1"	"126.9"	"248.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82650"	"28S ribosomal protein S22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS22 PE=1 SV=1"	"9"	"3"	"7"	"3"	"360"	"41.3"	"7.90"	"1320.53"	"8.65"	"3"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf10245"	"56945"	"ENSG00000175110"	"MRPS22"	"hsa:56945; P82650; Q9H3I1"	"Primary ovarian insufficiency"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"4"	"0"	"167.4"	"144.7"	"165.9"	"150.1"	"199.1"	"151.2"	"181.3"	"231.8"	"342.5"	"553.1"	"826.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35222"	"Catenin beta-1 OS=Homo sapiens OX=9606 GN=CTNNB1 PE=1 SV=1"	"5"	"4"	"6"	"3"	"781"	"85.4"	"5.86"	"1443.80"	"8.64"	"4"	"2"	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00514"	"1499"	"ENSG00000168036"	"CTNNB1"	"A8K1L7; hsa:1499; P35222; Q8NEW9; Q8NI94; Q9H391"	"Androgen receptor signaling pathway; MicroRNAs in cardiomyocyte hypertrophy; Heart development; TNF-related weak inducer of apoptosis (TWEAK) signaling pathway; Alzheimer's disease and miRNA effects; Neural crest differentiation; Arrhythmogenic right ventricular cardiomyopathy; Pathogenic Escherichia coli infection; Corticotropin-releasing hormone signaling pathway; Adipogenesis; Gastric cancer network 2; Brain-derived neurotrophic factor (BDNF) signaling pathway; Primary focal segmental glomerulosclerosis (FSGS); Endoderm differentiation; Ectoderm differentiation; Extracellular vesicle-mediated signaling in recipient cells; Focal adhesion; Ectoderm differentiation; RAC1/PAK1/p38/MMP2 pathway; Wnt signaling pathway; Regulation of Wnt / B-catenin signaling by small molecule compounds; Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; Embryonic stem cell pluripotency pathways; H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity; OSX and miRNAs in tooth development; Wnt signaling pathway and pluripotency; PTF1A related regulatory pathway; Wnt signaling in kidney disease; Endometrial cancer; Chromosomal and microsatellite instability in colorectal cancer ; Epithelial to mesenchymal transition in colorectal cancer; lncRNA in canonical Wnt signaling and colorectal cancer; Breast cancer pathway; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Ciliary landscape; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; Gastrin signaling pathway; Head and neck squamous cell carcinoma; Thyroid hormones production and peripheral downstream signaling effects; IL-18 signaling pathway; Osteoblast differentiation and related diseases; TGF-beta receptor signaling in skeletal dysplasias; Genes controlling nephrogenesis; GDNF/RET signaling axis; Mammalian disorder of sexual development; Influence of laminopathies on Wnt signaling; Overlap between signal transduction pathways contributing to LMNA laminopathies; 1q21.1 copy number variation syndrome; 7q11.23 copy number variation syndrome; Development of ureteric collection system; Pleural mesothelioma; Alzheimer's disease; Urotensin-II-mediated signaling pathway; Markers of kidney cell lineage; TROP2 regulatory signaling; 8p23.1 copy number variation syndrome; A network map of Macrophage-stimulating protein (MSP) signaling; TGF-beta receptor signaling; Sudden infant death syndrome (SIDS) susceptibility pathways; DNA damage response (only ATM dependent)"	"Somitogenesis; Deactivation of the beta-catenin transactivating complex; InlA-mediated entry of Listeria monocytogenes into host cells; RHO GTPases activate IQGAPs; Formation of paraxial mesoderm; Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1); Formation of axial mesoderm; Myogenesis; Transcriptional Regulation by VENTX; Ca2+ pathway; Disassembly of the destruction complex and recruitment of AXIN to the membrane; Beta-catenin phosphorylation cascade; Signaling by GSK3beta mutants; CTNNB1 S33 mutants aren't phosphorylated; CTNNB1 S37 mutants aren't phosphorylated; CTNNB1 S45 mutants aren't phosphorylated; CTNNB1 T41 mutants aren't phosphorylated; Cardiogenesis; Germ layer formation at gastrulation; Formation of definitive endoderm; VEGFR2 mediated vascular permeability; Adherens junctions interactions; Regulation of CDH11 function; Regulation of CDH19 Expression and Function; CDH11 homotypic and heterotypic interactions; Binding of TCF/LEF:CTNNB1 to target gene promoters; RUNX3 regulates WNT signaling; Apoptotic cleavage of cell adhesion  proteins; LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production"	"96"	"1"	"288.6"	"341.9"	"319.0"	"245.9"	"296.9"	"289.3"	"358.3"	"461.0"	"730.0"	"1331.9"	"2129.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BYW2"	"Histone-lysine N-methyltransferase SETD2 OS=Homo sapiens OX=9606 GN=SETD2 PE=1 SV=3"	"1"	"4"	"7"	"4"	"2564"	"287.4"	"6.14"	"1318.33"	"8.63"	"4"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00397, Pf00856, Pf08236, Pf17907"	"29072"	"ENSG00000181555"	"SETD2"	"hsa:29072; O75397; O75405; Q17RW8; Q5BKS9; Q5QGN2; Q69YI5; Q6IN64; Q6ZN53; Q6ZS25; Q8N3R0; Q8TCN0; Q9BYW2; Q9C0D1; Q9H696; Q9NZW9"	"Histone modifications; Mesodermal commitment pathway; Mesodermal commitment pathway; Pathways affected in adenoid cystic carcinoma; Clear cell renal cell carcinoma pathways; Type 2 papillary renal cell carcinoma; Pleural mesothelioma"	"PKMTs methylate histone lysines"	"8"	"0"	"408.1"	"298.7"	"466.2"	"369.7"	"448.1"	"436.1"	"458.8"	"532.3"	"806.4"	"1425.3"	"2063.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16637"	"Survival motor neuron protein OS=Homo sapiens OX=9606 GN=SMN1 PE=1 SV=1"	"12"	"4"	"6"	"4"	"294"	"31.8"	"6.55"	"1600.48"	"8.63"	"4"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06003"	"6606; 6607"	"ENSG00000172062; ENSG00000205571; ENSG00000273772; ENSG00000275349; ENSG00000277773"	"SMN1; SMN2"	"A8K0V4; hsa:6606; hsa:6607; Q13119; Q16637; Q549U5; Q96J51"	""	"snRNP Assembly; SARS-CoV-2 modulates host translation machinery"	"2"	"0"	"442.6"	"413.9"	"491.6"	"437.9"	"461.3"	"412.6"	"508.3"	"589.4"	"929.2"	"1747.4"	"2690.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99961"	"Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1"	"7"	"2"	"3"	"2"	"368"	"41.5"	"5.43"	"432.10"	"8.62"	"1"	"2"	"cell organization and biogenesis;transport;developmental processes;signal transduction"	"other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00018, Pf03114"	"6455"	"ENSG00000141985"	"SH3GL1"	"B4DRA1; E7EVZ4; hsa:6455; M0QZV5; Q99668; Q99961"	"Fragile X syndrome"	"Cargo recognition for clathrin-mediated endocytosis; EGFR downregulation; Negative regulation of MET activity; InlB-mediated entry of Listeria monocytogenes into host cell"	"6"	"0"	"36.4"	"24.3"	"48.4"	"35.5"	"34.9"	"38.0"	"49.4"	"63.5"	"139.9"	"551.9"	"1750.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q08378"	"Golgin subfamily A member 3 OS=Homo sapiens OX=9606 GN=GOLGA3 PE=1 SV=2"	"2"	"3"	"6"	"3"	"1498"	"167.3"	"5.44"	"782.32"	"8.60"	"3"	"3"	""	"other membranes;cytosol;ER/Golgi;nucleus"	""	""	"2802"	"ENSG00000090615"	"GOLGA3"	"A5PKX6; hsa:2802; O43241; Q08378; Q6P9C7; Q86XW3; Q8TDA9; Q8WZA3"	""	"RND2 GTPase cycle"	"1"	"0"	"16.4"	"17.8"	"31.0"	"32.0"	"33.6"	"29.2"	"30.3"	"50.5"	"104.3"	"192.1"	"300.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15054"	"DNA polymerase delta subunit 3 OS=Homo sapiens OX=9606 GN=POLD3 PE=1 SV=2"	"7"	"3"	"5"	"3"	"466"	"51.4"	"9.35"	"678.11"	"8.60"	"2"	"3"	"DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf09507"	"10714"	"ENSG00000077514"	"POLD3"	"B7ZAI6; hsa:10714; Q15054; Q32MZ9; Q32N00"	"Homologous recombination; Retinoblastoma gene in cancer; Pyrimidine metabolism; DNA replication; Base excision repair; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"HDR through Homologous Recombination (HRR); Termination of translesion DNA synthesis; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Polymerase switching on the C-strand of the telomere; Polymerase switching; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"26"	"0"	"113.3"	"104.0"	"138.8"	"114.1"	"130.8"	"136.8"	"145.7"	"161.7"	"382.7"	"672.1"	"788.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y6D9"	"Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2"	"6"	"4"	"7"	"4"	"718"	"83.0"	"5.92"	"1261.44"	"8.60"	"4"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf05557"	"8379"	"ENSG00000002822"	"MAD1L1"	"B3KR41; hsa:8379; Q13312; Q75MI0; Q86UM4; Q9UNH0; Q9Y6D9"	"Cell cycle; Regulation of sister chromatid separation at the metaphase-anaphase transition; Pleural mesothelioma; CCL18 signaling pathway"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"10"	"0"	"205.5"	"170.7"	"219.2"	"193.2"	"213.3"	"239.8"	"230.7"	"283.2"	"430.7"	"681.7"	"829.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y224"	"RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1"	"14"	"3"	"5"	"3"	"244"	"28.1"	"6.65"	"1301.88"	"8.59"	"3"	"2"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf10036"	"51637"	"ENSG00000087302"	"RTRAF"	"hsa:51637; Q9Y224"	""	"tRNA processing in the nucleus"	"1"	"0"	"350.1"	"287.5"	"310.1"	"310.6"	"326.7"	"331.0"	"396.5"	"427.3"	"626.7"	"980.7"	"1275.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62834"	"Ras-related protein Rap-1A OS=Homo sapiens OX=9606 GN=RAP1A PE=1 SV=1"	"15"	"2"	"3"	"2"	"184"	"21.0"	"6.67"	"562.65"	"8.58"	"1"	"2"	"cell-cell signaling;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00071"	"5906"	"ENSG00000116473"	"RAP1A"	"hsa:5906; P10113; P62834"	"Integrin-mediated cell adhesion; Thyroid stimulating hormone (TSH) signaling pathway; Androgen receptor network in prostate cancer; Brain-derived neurotrophic factor (BDNF) signaling pathway; Common pathways underlying drug addiction; Focal adhesion; Hepatocyte growth factor receptor signaling; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Ras signaling; EGF/EGFR signaling pathway; Leukocyte-intrinsic Hippo pathway functions; DNA repair pathways, full network; GDNF signaling; Interferon type I signaling pathways; Serotonin HTR1 group and FOS pathway; Serotonin receptor 4/6/7 and NR3C signaling"	"Neutrophil degranulation; Signaling by BRAF and RAF1 fusions; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; Rap1 signalling; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; Frs2-mediated activation; ARMS-mediated activation; GRB2:SOS provides linkage to MAPK signaling for Integrins ; p130Cas linkage to MAPK signaling for integrins; MET activates RAP1 and RAC1"	"34"	"0"	"113.0"	"102.6"	"144.6"	"124.7"	"146.2"	"116.4"	"175.3"	"228.5"	"447.4"	"690.0"	"792.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UFW8"	"CGG triplet repeat-binding protein 1 OS=Homo sapiens OX=9606 GN=CGGBP1 PE=1 SV=2"	"19"	"3"	"5"	"3"	"167"	"18.8"	"8.95"	"559.09"	"8.56"	"2"	"3"	"cell organization and biogenesis;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	""	"8545"	"ENSG00000163320"	"CGGBP1"	"D3DU38; hsa:8545; O15183; Q9UFW8"	""	""	"0"	"0"	"182.2"	"148.7"	"178.1"	"162.3"	"187.5"	"186.4"	"210.6"	"250.1"	"468.9"	"748.1"	"949.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46782"	"40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4"	"22"	"3"	"6"	"3"	"204"	"22.9"	"9.72"	"1080.59"	"8.55"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00177"	"6193"	"ENSG00000083845"	"RPS5"	"B2R4T2; hsa:6193; P46782; Q96BN0"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"220.8"	"312.1"	"188.0"	"166.5"	"188.5"	"195.5"	"253.8"	"370.4"	"554.0"	"801.5"	"909.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86W92"	"Liprin-beta-1 OS=Homo sapiens OX=9606 GN=PPFIBP1 PE=1 SV=2"	"4"	"3"	"6"	"3"	"1011"	"114.0"	"5.55"	"905.70"	"8.54"	"2"	"3"	"cell adhesion;cell organization and biogenesis"	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf00536, Pf07647"	"8496"	"ENSG00000110841"	"PPFIBP1"	"hsa:8496; O75336; Q86W92; Q86X70; Q9NY03; Q9ULJ0"	""	"Signaling by ALK fusions and activated point mutants; Receptor-type tyrosine-protein phosphatases"	"2"	"0"	"91.1"	"99.0"	"93.1"	"79.5"	"101.5"	"101.9"	"117.7"	"146.7"	"190.5"	"263.8"	"345.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UIL1"	"Short coiled-coil protein OS=Homo sapiens OX=9606 GN=SCOC PE=1 SV=2"	"18"	"2"	"4"	"2"	"159"	"18.0"	"8.85"	"884.90"	"8.54"	"2"	"2"	"other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus"	""	"Pf10224"	"60592"	"ENSG00000153130"	"SCOC"	"B7WPH7; D3DNY7; E9PB65; hsa:60592; Q6P5T9; Q7L2Y0; Q7Z4P2; Q96JY9; Q9BZB2; Q9UIL1"	""	"Retrograde transport at the Trans-Golgi-Network"	"1"	"0"	"135.5"	"112.0"	"148.9"	"148.4"	"138.6"	"151.2"	"179.3"	"206.1"	"286.4"	"497.2"	"717.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UHB9"	"Signal recognition particle subunit SRP68 OS=Homo sapiens OX=9606 GN=SRP68 PE=1 SV=2"	"6"	"3"	"6"	"3"	"627"	"70.7"	"8.56"	"996.51"	"8.53"	"3"	"3"	"transport;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf16969"	"6730"	"ENSG00000167881"	"SRP68"	"B3KUU5; B3KWY7; G3V1U4; hsa:6730; Q8NCJ4; Q8WUK2; Q9UHB9"	""	"SRP-dependent cotranslational protein targeting to membrane"	"1"	"0"	"88.9"	"86.3"	"94.8"	"82.2"	"89.4"	"86.0"	"105.8"	"153.9"	"235.6"	"558.3"	"1022.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75717"	"WD repeat and HMG-box DNA-binding protein 1 OS=Homo sapiens OX=9606 GN=WDHD1 PE=1 SV=1"	"2"	"2"	"4"	"2"	"1129"	"125.9"	"5.62"	"844.00"	"8.49"	"2"	"2"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400, Pf12341, Pf12894"	"11169"	"ENSG00000198554"	"WDHD1"	"C9JW18; F6W0U7; hsa:11169; O75717"	"Mesodermal commitment pathway"	""	"1"	"0"	"180.7"	"124.3"	"165.5"	"158.8"	"173.7"	"169.0"	"206.8"	"230.0"	"454.1"	"906.4"	"1303.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NFW8"	"N-acylneuraminate cytidylyltransferase OS=Homo sapiens OX=9606 GN=CMAS PE=1 SV=2"	"6"	"3"	"5"	"3"	"434"	"48.3"	"7.93"	"639.31"	"8.47"	"2"	"3"	"other metabolic processes"	"nucleus"	"other molecular function"	"Pf02348"	"55907"	"ENSG00000111726"	"CMAS"	"hsa:55907; Q8NFW8; Q96AX5; Q9NQZ0"	""	"Sialic acid metabolism"	"1"	"0"	"88.5"	"115.3"	"78.8"	"74.2"	"111.9"	"67.5"	"133.4"	"214.4"	"355.8"	"424.4"	"480.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99549"	"M-phase phosphoprotein 8 OS=Homo sapiens OX=9606 GN=MPHOSPH8 PE=1 SV=2"	"2"	"1"	"4"	"1"	"860"	"97.1"	"6.06"	"976.42"	"8.45"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00385, Pf12796"	"54737"	"ENSG00000196199"	"MPHOSPH8"	"B7Z6F9; hsa:54737; Q5JPE5; Q5JTQ0; Q86TK3; Q96MK4; Q99549; Q9BTP1"	""	""	"0"	"0"	"91.0"	"74.7"	"110.0"	"91.5"	"108.5"	"118.6"	"119.9"	"150.4"	"358.3"	"699.1"	"884.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H8H0"	"Nucleolar protein 11 OS=Homo sapiens OX=9606 GN=NOL11 PE=1 SV=1"	"4"	"2"	"4"	"2"	"719"	"81.1"	"6.07"	"801.31"	"8.44"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	"Pf08168"	"25926"	"ENSG00000130935"	"NOL11"	"B7Z5V9; hsa:25926; Q7L5S1; Q9H8H0; Q9UG18"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"17.2"	"13.9"	"20.1"	"26.2"	"21.0"	"13.9"	"28.5"	"27.5"	"75.8"	"137.8"	"206.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6W2J9"	"BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1"	"2"	"4"	"6"	"4"	"1755"	"192.1"	"6.48"	"921.18"	"8.42"	"3"	"3"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf12796, Pf15808, Pf16553"	"54880"	"ENSG00000183337"	"BCOR"	"D3DWB3; D3DWB4; hsa:54880; Q29RF6; Q6P4B6; Q6W2J9; Q7Z2K7; Q8TEB4; Q96DB3; Q9H232; Q9H233; Q9HCJ7; Q9NXF2"	"Ectoderm differentiation; Pathways affected in adenoid cystic carcinoma; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma"	""	"3"	"0"	"268.8"	"233.1"	"285.3"	"255.4"	"306.3"	"308.9"	"343.4"	"390.5"	"557.5"	"995.4"	"1287.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z4H7"	"HAUS augmin-like complex subunit 6 OS=Homo sapiens OX=9606 GN=HAUS6 PE=1 SV=2"	"5"	"3"	"5"	"3"	"955"	"108.6"	"6.47"	"1554.43"	"8.42"	"3"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton"	"cytoskeletal activity"	"Pf14661"	"54801"	"ENSG00000147874"	"HAUS6"	"B3KPK4; B4DX82; hsa:54801; Q05CG1; Q14CB6; Q14CD9; Q2TA91; Q6IQ10; Q6NZX5; Q7Z4H7; Q8IZQ4; Q96FN0; Q9H950; Q9H998; Q9HCJ8; Q9NXT8"	""	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"7"	"0"	"41.5"	"38.3"	"49.9"	"46.4"	"51.4"	"55.0"	"55.4"	"62.9"	"135.8"	"224.4"	"271.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WVM7"	"Cohesin subunit SA-1 OS=Homo sapiens OX=9606 GN=STAG1 PE=1 SV=3"	"4"	"4"	"5"	"2"	"1258"	"144.3"	"5.59"	"510.38"	"8.40"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf08514"	"10274"	"ENSG00000118007"	"STAG1"	"hsa:10274; O00539; Q6P275; Q8WVM7"	"Cell cycle; Regulation of sister chromatid separation at the metaphase-anaphase transition; 10q22q23 copy number variation"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Meiotic synapsis; Estrogen-dependent gene expression; SUMOylation of DNA damage response and repair proteins; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"10"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NWB6"	"Arginine and glutamate-rich protein 1 OS=Homo sapiens OX=9606 GN=ARGLU1 PE=1 SV=1"	"11"	"4"	"6"	"4"	"273"	"33.2"	"10.35"	"1225.89"	"8.40"	"4"	"2"	""	"cytosol;mitochondrion;nucleus"	""	"Pf15346"	"55082"	"ENSG00000134884"	"ARGLU1"	"B4E0Y3; hsa:55082; Q5T257; Q6IQ34; Q9NWB6"	""	""	"0"	"0"	"824.4"	"690.9"	"934.8"	"792.5"	"839.5"	"837.4"	"1000.3"	"1326.0"	"2473.5"	"3610.4"	"4583.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14818"	"Proteasome subunit alpha type-7 OS=Homo sapiens OX=9606 GN=PSMA7 PE=1 SV=1"	"9"	"2"	"4"	"2"	"248"	"27.9"	"8.46"	"851.89"	"8.40"	"2"	"2"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00227, Pf10584"	"5688"	"ENSG00000101182"	"PSMA7"	"B2R515; hsa:5688; O14818; Q5JXJ2; Q9BR53; Q9H4K5; Q9UEU8"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"62"	"0"	"83.7"	"79.5"	"92.2"	"103.1"	"103.2"	"104.9"	"128.5"	"169.4"	"406.1"	"685.5"	"1380.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14156"	"Protein EFR3 homolog A OS=Homo sapiens OX=9606 GN=EFR3A PE=1 SV=2"	"4"	"3"	"5"	"3"	"821"	"92.9"	"6.70"	"589.61"	"8.37"	"2"	"3"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol"	""	""	"23167"	"ENSG00000132294"	"EFR3A"	"A7MD19; hsa:23167; Q14156; Q2VPK2; Q63HL7; Q68DX1; Q6IQ18"	""	""	"0"	"0"	"107.7"	"84.1"	"116.8"	"96.7"	"115.3"	"101.8"	"122.0"	"180.2"	"380.0"	"527.1"	"650.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94887"	"FERM, ARHGEF and pleckstrin domain-containing protein 2 OS=Homo sapiens OX=9606 GN=FARP2 PE=1 SV=3"	"3"	"3"	"5"	"3"	"1054"	"119.8"	"8.79"	"570.81"	"8.37"	"2"	"3"	"cell adhesion;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;cytoskeletal activity"	"Pf00169, Pf00373, Pf00621, Pf08736, Pf09379, Pf09380"	"9855"	"ENSG00000006607"	"FARP2"	"B7Z6J8; F5GZ84; hsa:9855; O94887; Q53QM5; Q8WU27; Q9UFE7"	"2q37 copy number variation syndrome; TAR syndrome"	"RAC1 GTPase cycle; SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"	"4"	"0"	"134.4"	"112.8"	"144.2"	"125.0"	"137.9"	"117.6"	"165.6"	"206.6"	"277.9"	"490.7"	"641.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NYK5"	"39S ribosomal protein L39, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL39 PE=1 SV=3"	"7"	"2"	"4"	"2"	"338"	"38.7"	"7.65"	"786.92"	"8.37"	"2"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	""	"54148"	"ENSG00000154719"	"MRPL39"	"C9JYA5; hsa:54148; Q32Q74; Q5QTR3; Q96Q65; Q9BSQ7; Q9BZV6; Q9NX44; Q9NYK5"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"59.4"	"57.0"	"65.0"	"50.7"	"66.2"	"63.5"	"74.5"	"107.2"	"234.7"	"674.1"	"1325.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H4L7"	"SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 OS=Homo sapiens OX=9606 GN=SMARCAD1 PE=1 SV=2"	"3"	"2"	"4"	"2"	"1026"	"117.3"	"5.55"	"891.22"	"8.34"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271"	"56916"	"ENSG00000163104"	"SMARCAD1"	"B7Z799; hsa:56916; Q05D56; Q96SX1; Q9H017; Q9H4L7; Q9H860; Q9NPU9; Q9ULU7"	""	""	"0"	"0"	"116.7"	"127.5"	"133.1"	"133.4"	"137.8"	"141.9"	"148.0"	"177.4"	"237.4"	"614.4"	"949.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IXB1"	"DnaJ homolog subfamily C member 10 OS=Homo sapiens OX=9606 GN=DNAJC10 PE=1 SV=2"	"4"	"2"	"3"	"2"	"793"	"91.0"	"7.18"	"492.84"	"8.33"	"1"	"2"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"ER/Golgi"	"other molecular function"	"Pf00085, Pf00226"	"54431"	"ENSG00000077232"	"DNAJC10"	"hsa:54431; Q17RJ6; Q3B7W8; Q4ZG06; Q53QT7; Q6UWZ6; Q86T61; Q8IXB1; Q8NC82; Q8TD87; Q96K38; Q96K44; Q96K54; Q9NSY6"	""	""	"0"	"0"	"38.7"	"37.6"	"36.8"	"41.5"	"41.6"	"40.4"	"44.6"	"64.4"	"112.8"	"195.8"	"224.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9GZL7"	"Ribosome biogenesis protein WDR12 OS=Homo sapiens OX=9606 GN=WDR12 PE=1 SV=2"	"7"	"2"	"4"	"2"	"423"	"47.7"	"5.90"	"925.25"	"8.30"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00400, Pf08154"	"55759"	"ENSG00000138442"	"WDR12"	"B3KPA9; hsa:55759; Q96HU0; Q9GZL7; Q9NV80; Q9NYI8"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"75.9"	"71.3"	"86.1"	"67.3"	"77.0"	"85.2"	"101.1"	"134.8"	"224.3"	"389.1"	"880.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75323"	"Protein NipSnap homolog 2 OS=Homo sapiens OX=9606 GN=NIPSNAP2 PE=1 SV=1"	"8"	"3"	"5"	"1"	"286"	"33.7"	"9.36"	"622.43"	"8.29"	"2"	"3"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"other membranes;mitochondrion"	""	"Pf07978"	"2631"	"ENSG00000146729"	"NIPSNAP2"	"C9IYJ3; hsa:2631; O43801; O75323; Q53X96"	""	"RHOJ GTPase cycle; RHOH GTPase cycle"	"2"	"0"	"93.1"	"90.1"	"106.8"	"97.9"	"104.7"	"117.1"	"121.0"	"114.7"	"178.4"	"251.9"	"350.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HCS7"	"Pre-mRNA-splicing factor SYF1 OS=Homo sapiens OX=9606 GN=XAB2 PE=1 SV=2"	"3"	"2"	"4"	"2"	"855"	"99.9"	"6.23"	"1018.48"	"8.28"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes"	"nucleus;other cell component"	""	"Pf13181"	"56949"	"ENSG00000076924"	"XAB2"	"hsa:56949; Q8TET6; Q96HB0; Q96IW0; Q9HCS7; Q9NRG6; Q9ULP3"	"Rett syndrome causing genes; Nucleotide excision repair in xeroderma pigmentosum"	"mRNA Splicing - Major Pathway; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	"7"	"0"	"63.0"	"53.4"	"82.8"	"62.4"	"68.5"	"66.7"	"83.3"	"97.7"	"150.4"	"314.8"	"505.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09496"	"Clathrin light chain A OS=Homo sapiens OX=9606 GN=CLTA PE=1 SV=1"	"16"	"5"	"8"	"5"	"248"	"27.1"	"4.51"	"1506.45"	"8.28"	"5"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01086"	"1211"	"ENSG00000122705"	"CLTA"	"A8K4W3; B4DIN1; F5H6N3; hsa:1211; P09496; Q2XPN5; Q53XZ1"	"Synaptic vesicle pathway; Ebola virus infection in host; Fragile X syndrome"	"Cargo recognition for clathrin-mediated endocytosis; LDL clearance; Recycling pathway of L1; MHC class II antigen presentation; Lysosome Vesicle Biogenesis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; Retrograde neurotrophin signalling; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; VLDLR internalisation and degradation; Entry of Influenza Virion into Host Cell via Endocytosis; Formation of annular gap junctions"	"17"	"0"	"770.5"	"686.8"	"803.1"	"699.8"	"727.1"	"681.3"	"857.2"	"950.1"	"1067.2"	"1235.2"	"1553.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P10155"	"60 kDa SS-A/Ro ribonucleoprotein OS=Homo sapiens OX=9606 GN=RO60 PE=1 SV=2"	"5"	"2"	"4"	"2"	"538"	"60.6"	"8.03"	"802.01"	"8.28"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05731"	"6738"	"ENSG00000116747"	"RO60"	"B2RBB9; hsa:6738; P10155; Q5LJ98; Q5LJ99; Q5LJA0; Q86WL3; Q86WL4; Q92787; Q9H1W6"	""	""	"0"	"0"	"123.8"	"111.2"	"150.0"	"135.8"	"122.6"	"120.8"	"157.8"	"221.9"	"290.5"	"442.2"	"595.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96SB4"	"SRSF protein kinase 1 OS=Homo sapiens OX=9606 GN=SRPK1 PE=1 SV=2"	"4"	"2"	"3"	"2"	"655"	"74.3"	"6.16"	"418.08"	"8.27"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"6732"	"ENSG00000096063"	"SRPK1"	"B4DS61; hsa:6732; Q12890; Q5R364; Q5R365; Q8IY12; Q96SB4"	"VEGFA-VEGFR2 signaling; mRNA processing"	"Maturation of nucleoprotein"	"3"	"0"	"43.6"	"54.6"	"65.9"	"54.0"	"59.0"	"55.1"	"58.1"	"85.5"	"154.6"	"400.2"	"662.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75348"	"V-type proton ATPase subunit G 1 OS=Homo sapiens OX=9606 GN=ATP6V1G1 PE=1 SV=3"	"17"	"2"	"5"	"2"	"118"	"13.7"	"8.79"	"696.00"	"8.25"	"2"	"2"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf03179"	"9550"	"ENSG00000136888"	"ATP6V1G1"	"hsa:9550; O75348; Q6IB33"	"Osteoclast signaling; Proximal tubule transport"	"Amino acids regulate mTORC1; ROS and RNS production in phagocytes; Insulin receptor recycling; Transferrin endocytosis and recycling; Ion channel transport"	"7"	"0"	"207.5"	"238.5"	"202.8"	"195.4"	"209.4"	"202.6"	"261.6"	"332.4"	"531.6"	"860.9"	"1225.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5J9"	"Mitochondrial import inner membrane translocase subunit Tim8 B OS=Homo sapiens OX=9606 GN=TIMM8B PE=1 SV=1"	"31"	"3"	"6"	"3"	"83"	"9.3"	"5.12"	"1007.69"	"8.24"	"3"	"3"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf02953"	"26521"	"ENSG00000150779"	"TIMM8B"	"B0YJA5; hsa:26521; Q3KQS9; Q9UN04; Q9Y5J9"	""	"Mitochondrial protein import"	"1"	"0"	"192.1"	"152.8"	"217.0"	"194.5"	"202.3"	"209.1"	"243.9"	"338.4"	"593.5"	"1341.7"	"2591.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q07866"	"Kinesin light chain 1 OS=Homo sapiens OX=9606 GN=KLC1 PE=1 SV=2"	"5"	"2"	"3"	"2"	"573"	"65.3"	"6.20"	"616.23"	"8.24"	"1"	"2"	"cell adhesion;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf00515, Pf13374, Pf13424"	"3831"	"ENSG00000126214"	"KLC1"	"A6NF62; F8VTM4; hsa:3831; Q07866; Q7RTM2; Q7RTM3; Q7RTM5; Q7RTP9; Q7RTQ3; Q7RTQ5; Q7RTQ6; Q86SF5; Q86TF5; Q86V74; Q86V75; Q86V76; Q86V77; Q86V78; Q86V79; Q96H62"	"Alzheimer's disease and miRNA effects; IL-18 signaling pathway; Alzheimer's disease"	"COPI-dependent Golgi-to-ER retrograde traffic; MHC class II antigen presentation; Kinesins; Signaling by ALK fusions and activated point mutants; RHO GTPases activate KTN1"	"8"	"0"	"47.1"	"40.5"	"54.1"	"39.6"	"50.4"	"54.3"	"60.8"	"80.5"	"220.0"	"668.3"	"865.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46821"	"Microtubule-associated protein 1B OS=Homo sapiens OX=9606 GN=MAP1B PE=1 SV=2"	"1"	"2"	"4"	"2"	"2468"	"270.5"	"4.81"	"848.40"	"8.23"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00414"	"4131"	"ENSG00000131711"	"MAP1B"	"A2BDK5; hsa:4131; P46821"	"Microtubule cytoskeleton regulation; Fragile X syndrome; Neurogenesis regulation in the olfactory epithelium"	""	"3"	"0"	"185.3"	"151.7"	"182.4"	"173.0"	"167.8"	"196.3"	"210.7"	"244.3"	"459.4"	"635.2"	"806.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11233"	"Ras-related protein Ral-A OS=Homo sapiens OX=9606 GN=RALA PE=1 SV=1"	"11"	"2"	"5"	"2"	"206"	"23.6"	"7.11"	"611.51"	"8.22"	"2"	"2"	"cell cycle OR cell proliferation;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;mitochondrion;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00071"	"5898"	"ENSG00000006451"	"RALA"	"A4D1W3; hsa:5898; P11233"	"RalA downstream regulated genes; Chromosomal and microsatellite instability in colorectal cancer ; Ras signaling; Pancreatic adenocarcinoma pathway; EGF/EGFR signaling pathway"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; p38MAPK events"	"8"	"0"	"116.9"	"122.1"	"153.6"	"136.0"	"153.2"	"155.6"	"192.8"	"248.1"	"619.0"	"1124.1"	"1282.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WUD4"	"Coiled-coil domain-containing protein 12 OS=Homo sapiens OX=9606 GN=CCDC12 PE=1 SV=1"	"20"	"2"	"3"	"2"	"166"	"19.2"	"7.34"	"262.81"	"8.22"	"1"	"2"	""	"nucleus"	""	"Pf08315"	"151903"	"ENSG00000160799"	"CCDC12"	"hsa:151903; Q8N8I4; Q8WUD4"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"52.2"	"62.6"	"63.7"	"52.7"	"63.4"	"65.9"	"76.8"	"100.9"	"250.4"	"505.7"	"764.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBT7"	"Alpha-catulin OS=Homo sapiens OX=9606 GN=CTNNAL1 PE=1 SV=2"	"4"	"2"	"5"	"2"	"734"	"81.8"	"6.64"	"399.22"	"8.20"	"1"	"2"	"cell adhesion;signal transduction"	"plasma membrane;other membranes;cytosol;cytoskeleton"	"cytoskeletal activity;other molecular function"	"Pf01044"	"8727"	"ENSG00000119326"	"CTNNAL1"	"B5BU47; hsa:8727; O76084; Q53FQ2; Q5JTQ7; Q5JTQ8; Q9UBT7; Q9Y401"	""	""	"0"	"0"	"66.8"	"60.3"	"82.9"	"73.7"	"72.5"	"63.8"	"99.7"	"109.3"	"180.9"	"572.5"	"1281.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15294"	"UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Homo sapiens OX=9606 GN=OGT PE=1 SV=3"	"3"	"3"	"4"	"3"	"1046"	"116.9"	"6.70"	"577.66"	"8.19"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00515, Pf13181, Pf13414, Pf13424, Pf13844"	"8473"	"ENSG00000147162"	"OGT"	"hsa:8473; O15294; Q7Z3K0; Q8WWM8; Q96CC1; Q9UG57"	"Ectoderm differentiation; Ectoderm differentiation; Pleural mesothelioma"	"UCH proteinases; Formation of WDR5-containing histone-modifying complexes; Regulation of necroptotic cell death; HATs acetylate histones"	"8"	"0"	"86.9"	"82.0"	"93.8"	"79.2"	"89.0"	"75.8"	"101.3"	"141.5"	"238.5"	"555.3"	"958.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86TJ2"	"Transcriptional adapter 2-beta OS=Homo sapiens OX=9606 GN=TADA2B PE=1 SV=2"	"10"	"4"	"7"	"4"	"420"	"48.4"	"7.83"	"1285.64"	"8.18"	"4"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00249"	"93624"	"ENSG00000173011"	"TADA2B"	"A0AUJ8; A4QMR7; B3KSN0; B3KU86; hsa:93624; Q6MZG9; Q86TJ2"	""	"Ub-specific processing proteases; HATs acetylate histones"	"2"	"0"	"97.7"	"98.2"	"96.5"	"91.7"	"117.1"	"112.2"	"118.6"	"184.4"	"371.8"	"599.4"	"722.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14320"	"Protein FAM50A OS=Homo sapiens OX=9606 GN=FAM50A PE=1 SV=2"	"7"	"3"	"6"	"3"	"339"	"40.2"	"6.83"	"1097.26"	"8.18"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	"Pf04921"	"9130"	"ENSG00000071859"	"FAM50A"	"A8KAQ4; B2R997; hsa:9130; Q14320; Q5HY37; Q6PJH5"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"164.9"	"153.1"	"147.1"	"149.8"	"173.3"	"180.4"	"202.7"	"204.8"	"809.0"	"1875.5"	"2204.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96IZ0"	"PRKC apoptosis WT1 regulator protein OS=Homo sapiens OX=9606 GN=PAWR PE=1 SV=1"	"10"	"2"	"3"	"2"	"340"	"36.5"	"5.41"	"328.80"	"8.14"	"1"	"2"	"cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	""	"5074"	"ENSG00000177425"	"PAWR"	"hsa:5074; O75796; Q6FHY9; Q8N700; Q96IZ0"	""	""	"0"	"0"	"75.8"	"89.2"	"86.4"	"76.9"	"86.8"	"83.6"	"96.7"	"129.3"	"296.7"	"689.9"	"884.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15372"	"Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1"	"9"	"2"	"3"	"2"	"352"	"39.9"	"6.54"	"368.05"	"8.13"	"1"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01398, Pf19445"	"8667"	"ENSG00000147677"	"EIF3H"	"hsa:8667; O15372"	"Translation factors; VEGFA-VEGFR2 signaling; Measles virus infection; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"10"	"0"	"34.5"	"34.9"	"47.6"	"37.7"	"44.2"	"49.7"	"54.1"	"60.8"	"112.0"	"200.4"	"399.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14802"	"DNA-directed RNA polymerase III subunit RPC1 OS=Homo sapiens OX=9606 GN=POLR3A PE=1 SV=2"	"2"	"2"	"3"	"1"	"1390"	"155.5"	"8.48"	"527.36"	"8.13"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00623, Pf04983, Pf04997, Pf04998, Pf05000"	"11128"	"ENSG00000148606"	"POLR3A"	"hsa:11128; O14802; Q8IW34; Q8TCW5"	"Pyrimidine metabolism; Cytosolic DNA-sensing pathway"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation"	"9"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92820"	"Gamma-glutamyl hydrolase OS=Homo sapiens OX=9606 GN=GGH PE=1 SV=2"	"14"	"4"	"8"	"4"	"318"	"35.9"	"7.11"	"1934.58"	"8.13"	"4"	"3"	"other metabolic processes"	"non-structural extracellular;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf07722"	"8836"	"ENSG00000137563"	"GGH"	"hsa:8836; Q92820"	"Fluoropyrimidine activity"	"Neutrophil degranulation"	"2"	"0"	"81.4"	"78.2"	"95.2"	"65.5"	"93.7"	"103.9"	"190.3"	"363.5"	"655.8"	"1265.5"	"2065.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62191"	"26S proteasome regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMC1 PE=1 SV=1"	"8"	"2"	"4"	"2"	"440"	"49.2"	"6.21"	"763.55"	"8.12"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf16450, Pf17862"	"5700"	"ENSG00000100764"	"PSMC1"	"B4DR63; hsa:5700; P49014; P62191; Q03527; Q6IAW0; Q6NW36; Q96AZ3"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"Regulation of expression of SLITs and ROBOs; RUNX1 regulates transcription of genes involved in differentiation of HSCs; N-glycan trimming in the ER and Calnexin/Calreticulin cycle; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"64"	"0"	"26.8"	"19.9"	"41.1"	"33.9"	"31.3"	"30.5"	"36.9"	"36.5"	"72.7"	"131.1"	"210.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NI36"	"WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1"	"3"	"2"	"4"	"2"	"951"	"105.3"	"7.53"	"728.63"	"8.07"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf00400, Pf04192, Pf12894"	"134430"	""	"WDR36"	"A2RUS4; hsa:134430; Q68E02; Q8N1Q2; Q8NI36"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"51.4"	"50.7"	"50.7"	"54.3"	"55.1"	"56.2"	"56.4"	"76.9"	"157.7"	"289.3"	"363.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96KP1"	"Exocyst complex component 2 OS=Homo sapiens OX=9606 GN=EXOC2 PE=1 SV=1"	"7"	"5"	"8"	"5"	"924"	"104.0"	"6.90"	"1790.98"	"8.07"	"5"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf01833, Pf15469"	"55770"	"ENSG00000112685"	"EXOC2"	"B2RBE6; hsa:55770; Q5JPC8; Q96AN6; Q96KP1; Q9NUZ8; Q9UJM7"	"RalA downstream regulated genes; Chromosomal and microsatellite instability in colorectal cancer ; Ras signaling; Ciliary landscape"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"7"	"0"	"27.3"	"22.0"	"47.6"	"37.3"	"31.7"	"38.8"	"54.4"	"90.1"	"346.0"	"584.1"	"658.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y6E0"	"Serine/threonine-protein kinase 24 OS=Homo sapiens OX=9606 GN=STK24 PE=1 SV=1"	"6"	"2"	"4"	"1"	"443"	"49.3"	"5.69"	"772.81"	"8.06"	"2"	"2"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"8428"	"ENSG00000102572"	"STK24"	"hsa:8428; O14840; Q5JV92; Q9Y6E0"	""	"Apoptotic cleavage of cellular proteins"	"2"	"0"	"20.7"	"21.3"	"23.3"	"20.8"	"23.3"	"18.3"	"24.3"	"37.1"	"75.2"	"131.2"	"222.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46087"	"Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NOP2 PE=1 SV=2"	"5"	"3"	"5"	"3"	"812"	"89.2"	"9.23"	"566.55"	"8.06"	"2"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf01189, Pf08062, Pf17125"	"4839"	"ENSG00000111641"	"NOP2"	"A1A4Z3; B3KPD6; hsa:4839; P46087; Q05BA7; Q0P5S5; Q3KQS4; Q58F30"	"Imatinib and chronic myeloid leukemia"	"rRNA modification in the nucleus and cytosol; TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"	"3"	"0"	"142.3"	"119.1"	"150.5"	"132.3"	"146.0"	"138.3"	"170.6"	"217.0"	"278.8"	"460.2"	"628.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25685"	"DnaJ homolog subfamily B member 1 OS=Homo sapiens OX=9606 GN=DNAJB1 PE=1 SV=4"	"8"	"3"	"5"	"2"	"340"	"38.0"	"8.63"	"644.87"	"8.06"	"2"	"3"	"protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00226, Pf01556"	"3337"	"ENSG00000132002"	"DNAJB1"	"B4DX52; hsa:3337; P25685"	"Nuclear receptors meta-pathway; NRF2 pathway"	"MAPK6/MAPK4 signaling; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Regulation of HSF1-mediated heat shock response; Attenuation phase"	"7"	"1"	"420.0"	"362.9"	"463.9"	"355.6"	"452.0"	"438.5"	"510.6"	"557.7"	"767.9"	"1183.8"	"1471.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96QE3"	"ATPase family AAA domain-containing protein 5 OS=Homo sapiens OX=9606 GN=ATAD5 PE=1 SV=4"	"2"	"2"	"3"	"2"	"1844"	"207.4"	"9.19"	"293.88"	"8.02"	"1"	"2"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00004"	"79915"	"ENSG00000176208"	"ATAD5"	"hsa:79915; Q05DH0; Q69YR6; Q96QE3; Q9H9I1"	""	""	"0"	"0"	"37.0"	"26.4"	"45.2"	"45.6"	"46.9"	"44.9"	"48.7"	"71.6"	"156.7"	"188.1"	"224.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62333"	"26S proteasome regulatory subunit 10B OS=Homo sapiens OX=9606 GN=PSMC6 PE=1 SV=1"	"7"	"2"	"4"	"2"	"389"	"44.1"	"7.49"	"892.28"	"8.01"	"2"	"2"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf16450, Pf17862"	"5706"	"ENSG00000100519"	"PSMC6"	"B2R975; hsa:5706; P49719; P62333; Q6IBU3; Q92524"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Ciliary landscape; Alzheimer's disease"	"The role of GTSE1 in G2/M progression after G2 checkpoint; Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; SARS-CoV-1 targets host intracellular signalling and regulatory pathways"	"65"	"0"	"108.9"	"113.1"	"140.0"	"109.5"	"120.6"	"115.1"	"160.5"	"214.9"	"326.7"	"596.6"	"1158.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N1G0"	"Zinc finger protein 687 OS=Homo sapiens OX=9606 GN=ZNF687 PE=1 SV=1"	"3"	"2"	"2"	"2"	"1237"	"129.4"	"8.19"	""	"7.97"	""	"2"	""	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00096, Pf16622"	"57592"	"ENSG00000143373"	"ZNF687"	"D3DV17; hsa:57592; Q68DQ8; Q8N1G0; Q9H937; Q9P2A7"	""	""	"0"	"0"	"81.5"	"16.0"	"164.5"	"101.6"	"99.5"	"108.1"	"111.4"	"148.9"	"560.2"	"930.0"	"1374.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15283"	"Ras GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=RASA2 PE=1 SV=3"	"2"	"2"	"6"	"2"	"850"	"96.6"	"7.20"	"830.53"	"7.95"	"2"	"2"	"signal transduction;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00168, Pf00169, Pf00616, Pf00779"	"5922"	"ENSG00000155903"	"RASA2"	"A8K7K1; G3V0F9; hsa:5922; O00695; Q15283; Q15284; Q92594; Q99577; Q9UEQ2"	"MAPK signaling pathway; Ebola virus infection in host; Ras signaling; Modulators of TCR signaling and T cell activation"	"Regulation of RAS by GAPs"	"5"	"0"	"37.7"	"40.6"	"47.5"	"40.5"	"46.4"	"66.3"	"153.1"	"376.8"	"293.2"	"299.5"	"347.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13131"	"5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens OX=9606 GN=PRKAA1 PE=1 SV=4"	"6"	"2"	"3"	"2"	"559"	"64.0"	"8.12"	"534.78"	"7.95"	"1"	"2"	"cell-cell signaling;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;kinase activity;other molecular function"	"Pf00069, Pf16579"	"5562"	"ENSG00000132356"	"PRKAA1"	"A8MTQ6; B2R7E1; hsa:5562; O00286; Q13131; Q5D0E1; Q86VS1; Q9UNQ4"	"AMP-activated protein kinase signaling; Target of rapamycin signaling; Energy metabolism; Thyroxine (thyroid hormone) production; Sterol regulatory element-binding proteins (SREBP) signaling; SREBF and miR33 in cholesterol and lipid homeostasis; Leptin signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; mir-124 predicted interactions with cell cycle and differentiation ; ATM signaling in development and disease ; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Leptin and adiponectin; Lipid metabolism pathway; PI3K-Akt signaling pathway; Thermogenesis; Nonalcoholic fatty liver disease; Synaptic signaling pathways associated with autism spectrum disorder; Hippo signaling regulation pathways; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Head and neck squamous cell carcinoma; IL-18 signaling pathway; Insulin signaling; 1q21.1 copy number variation syndrome; Autophagy; p53 transcriptional gene network; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Pleural mesothelioma; Disturbed pathways in Duchenne Muscular Dystrophy"	"Activation of AMPK downstream of NMDARs; Regulation of TP53 Activity through Phosphorylation; TP53 Regulates Metabolic Genes; Macroautophagy; Energy dependent regulation of mTOR by LKB1-AMPK"	"35"	"0"	"9.0"	"8.7"	"10.3"	"11.1"	"10.5"	"10.5"	"14.9"	"26.0"	"88.9"	"232.2"	"357.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P41223"	"Protein BUD31 homolog OS=Homo sapiens OX=9606 GN=BUD31 PE=1 SV=2"	"26"	"4"	"6"	"4"	"144"	"17.0"	"8.82"	"1548.46"	"7.95"	"4"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf01125"	"8896"	"ENSG00000106245"	"BUD31"	"A4D274; B7Z4S9; D6W5S6; hsa:8896; P41223; Q6IB53; Q9UDV1"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"156.7"	"175.4"	"179.8"	"154.0"	"192.0"	"192.9"	"227.0"	"291.5"	"481.5"	"956.8"	"1307.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NZ63"	"Telomere length and silencing protein 1 homolog OS=Homo sapiens OX=9606 GN=C9orf78 PE=1 SV=1"	"9"	"2"	"3"	"2"	"289"	"33.7"	"6.74"	"309.72"	"7.93"	"1"	"2"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf07052"	"51759"	"ENSG00000136819"	"C9orf78"	"B3KPX8; hsa:51759; Q8WVU6; Q9NT39; Q9NZ63"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"20.3"	"28.8"	"34.4"	"37.4"	"34.7"	"35.8"	"37.0"	"30.2"	"67.6"	"243.4"	"458.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62195"	"26S proteasome regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMC5 PE=1 SV=1"	"8"	"2"	"3"	"2"	"406"	"45.6"	"7.55"	"341.40"	"7.93"	"1"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00004, Pf16450, Pf17862"	"5705"	"ENSG00000087191"	"PSMC5"	"A8K3Z3; A8K763; hsa:5705; O35051; O43208; P47210; P52915; P52916; P62195"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Pregnane X receptor pathway; Nuclear receptors meta-pathway; Alzheimer's disease"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"65"	"0"	"17.8"	"30.3"	"35.6"	"24.1"	"24.0"	"21.4"	"28.7"	"41.1"	"95.0"	"178.9"	"392.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BTL3"	"RNA guanine-N7 methyltransferase activating subunit OS=Homo sapiens OX=9606 GN=RAMAC PE=1 SV=1"	"19"	"2"	"4"	"2"	"118"	"14.4"	"8.94"	"903.41"	"7.92"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf15320"	"83640"	"ENSG00000169612"	"RAMAC"	"hsa:83640; Q2M1J8; Q9BTL3"	"15q25 copy number variation"	""	"1"	"0"	"155.5"	"145.2"	"163.9"	"152.4"	"191.5"	"180.0"	"200.5"	"229.5"	"365.3"	"628.1"	"789.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BYD3"	"39S ribosomal protein L4, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL4 PE=1 SV=1"	"9"	"2"	"4"	"2"	"311"	"34.9"	"9.72"	"833.53"	"7.90"	"2"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00573"	"51073"	"ENSG00000105364"	"MRPL4"	"A6NNV7; hsa:51073; Q9BW07; Q9BYD3; Q9H4N2; Q9Y317"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"62.2"	"54.6"	"71.6"	"56.2"	"65.2"	"61.4"	"87.8"	"115.2"	"230.6"	"446.0"	"767.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P0DPB6"	"DNA-directed RNA polymerases I and III subunit RPAC2 OS=Homo sapiens OX=9606 GN=POLR1D PE=1 SV=1"	"20"	"2"	"4"	"2"	"133"	"15.2"	"5.80"	"897.05"	"7.90"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf13656"	"51082"	"ENSG00000186184"	"POLR1D"	"hsa:51082; P0DPB6; Q5TBX2; Q96BR3; Q9Y2S0"	"Pyrimidine metabolism; Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	""	"4"	"0"	"60.8"	"47.5"	"76.6"	"62.3"	"69.3"	"75.5"	"78.6"	"104.0"	"274.5"	"604.5"	"959.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q02224"	"Centromere-associated protein E OS=Homo sapiens OX=9606 GN=CENPE PE=1 SV=2"	"1"	"3"	"5"	"2"	"2701"	"316.2"	"5.64"	"609.26"	"7.89"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225"	"1062"	"ENSG00000138778"	"CENPE"	"A6NKY9; A8K2U7; hsa:1062; Q02224; Q4LE75"	"Regulation of sister chromatid separation at the metaphase-anaphase transition"	"RHO GTPases Activate Formins; MHC class II antigen presentation; COPI-dependent Golgi-to-ER retrograde traffic; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; EML4 and NUDC in mitotic spindle formation; Kinesins; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"10"	"0"	"3.7"	"3.6"	"5.6"	"4.0"	"5.8"	"6.8"	"6.7"	"11.5"	"18.6"	"36.5"	"40.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14136"	"Glial fibrillary acidic protein OS=Homo sapiens OX=9606 GN=GFAP PE=1 SV=1"	"8"	"3"	"4"	"1"	"432"	"49.9"	"5.52"	"423.42"	"7.89"	"1"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00038, Pf04732"	"2670"	"ENSG00000131095"	"GFAP"	"A7REI1; B2RD44; D3DX59; E9PAX3; hsa:2670; P14136; Q53H98; Q5D055; Q6ZQS3; Q7Z5J6; Q7Z5J7; Q96KS4; Q96P18; Q9UFD0"	"Neural crest differentiation; Spinal cord injury; Neuroinflammation and glutamatergic signaling"	"Nuclear signaling by ERBB4; Chaperone Mediated Autophagy"	"5"	"0"	"18.9"	"39.7"	"16.7"	"12.6"	"14.0"	"16.3"	"27.8"	"52.8"	"97.5"	"155.0"	"239.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2Q3"	"Glutathione S-transferase kappa 1 OS=Homo sapiens OX=9606 GN=GSTK1 PE=1 SV=3"	"12"	"2"	"4"	"2"	"226"	"25.5"	"8.41"	"756.87"	"7.89"	"2"	"2"	"other metabolic processes;other biological processes"	"cytosol;mitochondrion;other cytoplasmic organelle"	"other molecular function"	"Pf01323"	"373156"	"ENSG00000197448"	"GSTK1"	"B4DIH1; B4DSY2; hsa:373156; Q6P4H0; Q7Z520; Q9P1S4; Q9Y2Q3"	"Metapathway biotransformation Phase I and II"	"Peroxisomal protein import; Glutathione conjugation"	"3"	"0"	"53.0"	"64.7"	"67.7"	"53.4"	"67.9"	"65.4"	"88.5"	"147.0"	"427.9"	"1019.2"	"1217.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00178"	"GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=GTPBP1 PE=1 SV=3"	"3"	"2"	"6"	"2"	"669"	"72.4"	"8.34"	"792.85"	"7.87"	"2"	"2"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;other cytoplasmic organelle"	"nucleic acid binding activity;other molecular function"	"Pf00009"	"9567"	"ENSG00000100226"	"GTPBP1"	"hsa:9567; O00178; Q6IC67"	""	""	"0"	"0"	"5.5"	"3.9"	"5.8"	"3.7"	"5.1"	"3.2"	"8.4"	"6.6"	"19.7"	"41.0"	"57.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BVC3"	"Sister chromatid cohesion protein DCC1 OS=Homo sapiens OX=9606 GN=DSCC1 PE=1 SV=2"	"9"	"2"	"4"	"2"	"393"	"44.8"	"5.17"	"902.28"	"7.87"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf09724"	"79075"	"ENSG00000136982"	"DSCC1"	"hsa:79075; Q969N5; Q9BVC3"	"Gastric cancer network 2"	"Polymerase switching on the C-strand of the telomere"	"2"	"0"	"22.6"	"28.5"	"29.2"	"30.7"	"33.1"	"22.1"	"43.4"	"46.8"	"84.7"	"310.5"	"531.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5B6"	"PAX3- and PAX7-binding protein 1 OS=Homo sapiens OX=9606 GN=PAXBP1 PE=1 SV=2"	"5"	"3"	"5"	"3"	"917"	"104.7"	"5.68"	"953.41"	"7.86"	"3"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf07842"	"94104"	"ENSG00000159086; ENSG00000263141"	"PAXBP1"	"D3DSE7; hsa:94104; Q96DU8; Q9NYQ0; Q9Y5B6"	""	""	"0"	"0"	"167.6"	"144.1"	"164.8"	"154.2"	"155.7"	"165.9"	"188.9"	"197.8"	"244.4"	"570.8"	"1068.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P2E9"	"Enhancer of mRNA-decapping protein 4 OS=Homo sapiens OX=9606 GN=EDC4 PE=1 SV=1"	"2"	"2"	"3"	"2"	"1401"	"151.6"	"5.86"	"573.38"	"7.85"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf16529"	"23644"	"ENSG00000038358"	"EDC4"	"A6NGM1; A8K4T4; hsa:23644; Q13025; Q13826; Q6P2E9; Q6ZR12; Q7Z6H7"	""	"mRNA decay by 5' to 3' exoribonuclease"	"1"	"0"	"52.9"	"41.6"	"74.6"	"52.9"	"58.1"	"56.1"	"68.4"	"81.1"	"154.0"	"291.4"	"434.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14789"	"Golgin subfamily B member 1 OS=Homo sapiens OX=9606 GN=GOLGB1 PE=1 SV=2"	"1"	"3"	"5"	"2"	"3259"	"375.8"	"5.00"	"556.37"	"7.83"	"2"	"3"	"cell organization and biogenesis;other biological processes"	"other membranes;cytosol;ER/Golgi"	"nucleic acid binding activity"	""	"2804"	"ENSG00000173230"	"GOLGB1"	"B2ZZ91; D3DN92; E7EP74; F1T0J2; hsa:2804; Q14398; Q14789"	""	"Golgi Associated Vesicle Biogenesis; COPI-mediated anterograde transport; Signaling by FLT3 fusion proteins"	"3"	"0"	"11.7"	"7.9"	"17.0"	"9.4"	"12.6"	"11.3"	"11.2"	"19.2"	"72.8"	"130.1"	"231.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IXQ5"	"Kelch-like protein 7 OS=Homo sapiens OX=9606 GN=KLHL7 PE=1 SV=2"	"5"	"2"	"3"	"2"	"586"	"65.9"	"6.48"	"306.07"	"7.82"	"1"	"2"	"protein metabolism;other metabolic processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00651, Pf01344, Pf07707"	"55975"	"ENSG00000122550"	"KLHL7"	"A4D144; B7Z5I9; G5E9G3; hsa:55975; Q7Z765; Q8IXQ5; Q96MV2; Q9BQF8; Q9UDQ9"	""	""	"0"	"0"	"40.2"	"35.8"	"46.9"	"49.8"	"43.9"	"40.0"	"60.1"	"81.4"	"306.9"	"727.4"	"1144.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P59998"	"Actin-related protein 2/3 complex subunit 4 OS=Homo sapiens OX=9606 GN=ARPC4 PE=1 SV=3"	"16"	"3"	"6"	"3"	"168"	"19.7"	"8.43"	"962.07"	"7.82"	"3"	"3"	"cell organization and biogenesis"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf05856"	"10093"	"ENSG00000241553"	"ARPC4"	"C9JWM7; E7ETI0; F6TTL5; hsa:10093; O15509; P59998; Q6P0W5; Q96QJ3"	"Pathogenic Escherichia coli infection"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Clathrin-mediated endocytosis; EPHB-mediated forward signaling"	"6"	"0"	"63.7"	"77.4"	"91.6"	"68.7"	"76.1"	"71.9"	"96.1"	"132.6"	"606.1"	"1135.4"	"1492.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q969G3"	"SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Homo sapiens OX=9606 GN=SMARCE1 PE=1 SV=2"	"9"	"2"	"3"	"2"	"411"	"46.6"	"4.88"	"259.08"	"7.81"	"1"	"2"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00505"	"6605"	"ENSG00000073584"	"SMARCE1"	"B3KMC1; B4DFR4; C0IMW4; C0IMW5; C0IMW7; H7C3F6; hsa:6605; O43539; Q969G3"	"Androgen receptor signaling pathway; Pathways affected in adenoid cystic carcinoma; Tumor suppressor activity of SMARCB1; Thermogenesis"	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; RMTs methylate histone arginines"	"6"	"0"	"54.5"	"50.3"	"57.9"	"47.7"	"61.4"	"64.0"	"63.2"	"85.0"	"156.3"	"398.0"	"569.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16342"	"Programmed cell death protein 2 OS=Homo sapiens OX=9606 GN=PDCD2 PE=1 SV=2"	"5"	"1"	"4"	"1"	"344"	"38.6"	"5.38"	"833.87"	"7.79"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01753, Pf04194"	"5134"	"ENSG00000071994"	"PDCD2"	"E9PCU7; F5GYS7; hsa:5134; Q16342; Q58HM9; Q58HN0; Q9UH12"	""	""	"0"	"0"	"21.1"	"19.7"	"23.4"	"22.2"	"26.4"	"21.7"	"22.7"	"36.1"	"69.4"	"126.8"	"176.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63220"	"40S ribosomal protein S21 OS=Homo sapiens OX=9606 GN=RPS21 PE=1 SV=1"	"31"	"3"	"6"	"3"	"83"	"9.1"	"8.50"	"904.73"	"7.77"	"3"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01249"	"6227"	"ENSG00000171858"	"RPS21"	"hsa:6227; P35265; P63220"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"561.2"	"672.7"	"709.9"	"694.3"	"713.5"	"649.5"	"893.0"	"1114.5"	"1252.2"	"1640.6"	"2088.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UNP9"	"Peptidyl-prolyl cis-trans isomerase E OS=Homo sapiens OX=9606 GN=PPIE PE=1 SV=1"	"11"	"3"	"5"	"2"	"301"	"33.4"	"5.60"	"676.10"	"7.77"	"2"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00160"	"10450"	"ENSG00000084072"	"PPIE"	"B2R971; hsa:10450; O43634; O43635; Q32Q72; Q3S611; Q5TGA0; Q5TGA2; Q5TGA3; Q9UIZ5; Q9UNP9"	""	"mRNA Splicing - Major Pathway; Neutrophil degranulation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	"6"	"0"	"95.0"	"83.2"	"118.4"	"93.1"	"111.8"	"97.0"	"114.3"	"148.4"	"268.7"	"513.1"	"824.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UNM6"	"26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2"	"6"	"2"	"2"	"2"	"376"	"42.9"	"5.81"	""	"7.77"	""	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf01399"	"5719"	"ENSG00000185627"	"PSMD13"	"B3KT15; hsa:5719; O75831; Q53XU2; Q9UNM6; Q9UNV3"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Ciliary landscape; Alzheimer's disease"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"65"	"0"	"55.2"	"61.8"	"74.7"	"66.7"	"67.8"	"60.8"	"77.6"	"114.2"	"215.5"	"539.7"	"1177.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5SVZ6"	"Zinc finger MYM-type protein 1 OS=Homo sapiens OX=9606 GN=ZMYM1 PE=1 SV=1"	"2"	"2"	"5"	"2"	"1142"	"128.6"	"7.44"	"620.02"	"7.76"	"1"	"2"	""	"nucleus"	"other molecular function"	"Pf05699, Pf06467, Pf14291"	"79830"	"ENSG00000197056"	"ZMYM1"	"D3DPR7; hsa:79830; Q5SVZ6; Q7Z3Q4"	""	""	"0"	"0"	"78.2"	"69.6"	"80.8"	"89.1"	"96.1"	"91.1"	"97.2"	"108.9"	"201.5"	"515.5"	"752.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5MNZ6"	"WD repeat domain phosphoinositide-interacting protein 3 OS=Homo sapiens OX=9606 GN=WDR45B PE=1 SV=2"	"9"	"2"	"4"	"2"	"344"	"38.1"	"7.59"	"1047.42"	"7.74"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	""	"56270"	"ENSG00000141580"	"WDR45B"	"A0A024R8U4; A0A218N098; hsa:56270; O95328; Q2MCP6; Q5MNZ6; Q6IBN2"	""	"Macroautophagy"	"1"	"0"	"24.3"	"23.5"	"30.2"	"33.1"	"27.2"	"30.1"	"35.1"	"60.3"	"147.3"	"309.9"	"392.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15021"	"Condensin complex subunit 1 OS=Homo sapiens OX=9606 GN=NCAPD2 PE=1 SV=3"	"2"	"2"	"3"	"2"	"1401"	"157.1"	"6.61"	"378.80"	"7.74"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf12717, Pf12922"	"9918"	"ENSG00000010292"	"NCAPD2"	"D3DUR4; hsa:9918; Q15021; Q8N6U3"	""	"Condensation of Prometaphase Chromosomes"	"1"	"0"	"23.2"	"21.6"	"30.0"	"20.5"	"30.1"	"30.7"	"38.5"	"44.1"	"94.4"	"242.9"	"381.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P78316"	"Nucleolar protein 14 OS=Homo sapiens OX=9606 GN=NOP14 PE=1 SV=3"	"3"	"2"	"4"	"2"	"857"	"97.6"	"7.58"	"778.99"	"7.74"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04147"	"8602"	"ENSG00000087269"	"NOP14"	"D3DVR6; hsa:8602; P78316; Q7LGI5; Q7Z6K0; Q8TBR6"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"113.3"	"103.0"	"133.4"	"108.1"	"133.3"	"143.6"	"168.5"	"186.4"	"234.3"	"306.6"	"404.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15643"	"Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3"	"1"	"3"	"5"	"1"	"1979"	"227.4"	"5.26"	"513.29"	"7.74"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;cytoskeleton;ER/Golgi"	"other molecular function"	""	"9321"	"ENSG00000100815"	"TRIP11"	"B2RUT2; hsa:9321; O14689; O15154; O95949; Q15643; Q6MZL5"	""	"Intraflagellar transport; Intra-Golgi traffic; Signaling by FLT3 fusion proteins"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P48729"	"Casein kinase I isoform alpha OS=Homo sapiens OX=9606 GN=CSNK1A1 PE=1 SV=2"	"9"	"2"	"3"	"2"	"337"	"38.9"	"9.57"	"280.70"	"7.71"	"1"	"2"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"1452"	"ENSG00000113712"	"CSNK1A1"	"D3DQG0; D3DQG1; hsa:1452; P48729; Q4JJA0; Q5U046; Q5U047; Q6FGA2; Q71TU5; Q96HD2; Q9UDK3"	"Alzheimer's disease and miRNA effects; T cell receptor and co-stimulatory signaling; Complement system; Wnt signaling pathway; Wnt/beta-catenin signaling pathway in leukemia; Regulation of Wnt / B-catenin signaling by small molecule compounds; Chromosomal and microsatellite instability in colorectal cancer ; Hedgehog signaling pathway; lncRNA in canonical Wnt signaling and colorectal cancer; Breast cancer pathway; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Influence of laminopathies on Wnt signaling; Overlap between signal transduction pathways contributing to LMNA laminopathies; Pleural mesothelioma; Alzheimer's disease; DYRK1A involvement regarding cell proliferation in brain development"	"Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Disassembly of the destruction complex and recruitment of AXIN to the membrane; Beta-catenin phosphorylation cascade; Signaling by GSK3beta mutants; CTNNB1 S33 mutants aren't phosphorylated; CTNNB1 S37 mutants aren't phosphorylated; CTNNB1 S45 mutants aren't phosphorylated; CTNNB1 T41 mutants aren't phosphorylated; Activation of SMO; APC truncation mutants have impaired AXIN binding; AXIN missense mutants destabilize the destruction complex; Truncations of AMER1 destabilize the destruction complex; Maturation of nucleoprotein"	"32"	"0"	"53.6"	"64.5"	"56.4"	"46.0"	"48.1"	"51.9"	"74.7"	"95.8"	"139.4"	"180.6"	"192.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q1L5Z9"	"LON peptidase N-terminal domain and RING finger protein 2 OS=Homo sapiens OX=9606 GN=LONRF2 PE=2 SV=3"	"4"	"2"	"4"	"2"	"754"	"83.6"	"5.90"	"921.63"	"7.70"	"2"	"2"	""	"other cell component"	"other molecular function"	"Pf02190, Pf13923"	"164832"	"ENSG00000170500"	"LONRF2"	"B9A006; hsa:164832; Q1L5Z9; Q6ZSR4"	""	""	"0"	"0"	"19.6"	"20.2"	"20.8"	"24.9"	"29.8"	"20.2"	"24.7"	"43.2"	"147.7"	"422.9"	"675.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22059"	"Oxysterol-binding protein 1 OS=Homo sapiens OX=9606 GN=OSBP PE=1 SV=1"	"3"	"2"	"3"	"2"	"807"	"89.4"	"7.30"	"386.46"	"7.70"	"1"	"2"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf00169, Pf01237"	"5007"	"ENSG00000110048"	"OSBP"	"hsa:5007; P22059; Q6P524"	""	"Sphingolipid de novo biosynthesis; Synthesis of bile acids and bile salts"	"2"	"0"	"26.5"	"25.6"	"47.6"	"45.9"	"44.6"	"39.3"	"49.4"	"46.7"	"134.3"	"355.8"	"704.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60520"	"Gamma-aminobutyric acid receptor-associated protein-like 2 OS=Homo sapiens OX=9606 GN=GABARAPL2 PE=1 SV=1"	"16"	"2"	"3"	"1"	"117"	"13.7"	"8.10"	"436.76"	"7.69"	"1"	"2"	"cell organization and biogenesis;other metabolic processes;stress response;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf02991"	"11345"	"ENSG00000034713"	"GABARAPL2"	"hsa:11345; O08765; P60520; Q6FG91; Q9DCP8; Q9UQF7"	"Network map of SARS-CoV-2 signaling pathway; 2q37 copy number variation syndrome"	"Macroautophagy; TBC/RABGAPs"	"4"	"1"	"122.6"	"116.0"	"153.0"	"118.7"	"135.6"	"155.4"	"164.3"	"220.4"	"962.0"	"2420.0"	"3374.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P81605"	"Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2"	"25"	"3"	"4"	"3"	"110"	"11.3"	"6.54"	"271.00"	"7.66"	"1"	"3"	"protein metabolism;stress response;transport;other biological processes"	"non-structural extracellular;other membranes"	"transporter activity;other molecular function"	"Pf15291"	"117159"	"ENSG00000161634"	"DCD"	"A5JHP2; A5JHP3; hsa:117159; P58461; P81605; Q53YJ2"	""	"Antimicrobial peptides"	"1"	"0"	"144.5"	"405.5"	"1558.2"	"59.0"	"144.6"	"96.9"	"246.5"	"401.8"	"313.3"	"374.1"	"509.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96L93"	"Kinesin-like protein KIF16B OS=Homo sapiens OX=9606 GN=KIF16B PE=1 SV=2"	"3"	"2"	"3"	"2"	"1317"	"151.9"	"6.16"	"405.36"	"7.66"	"1"	"2"	"other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225, Pf00498, Pf00787"	"55614"	"ENSG00000089177"	"KIF16B"	"A6NKJ9; A7E2A8; B1AKG3; B1AKT7; C9JDN5; C9JI52; C9JSM8; C9JWJ7; hsa:55614; Q2TBF5; Q5HYC0; Q5HYK1; Q5JWW3; Q5TFK5; Q86VL9; Q86YS5; Q8IYU0; Q96L93; Q9BQJ8; Q9BQM0; Q9BQM1; Q9BQM5; Q9H5U0; Q9HCI2; Q9NXN9"	""	"COPI-dependent Golgi-to-ER retrograde traffic; Kinesins"	"2"	"0"	"59.4"	"48.0"	"63.4"	"52.4"	"62.8"	"64.5"	"67.8"	"107.9"	"293.9"	"377.9"	"390.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NYU2"	"UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3"	"3"	"2"	"3"	"2"	"1555"	"177.1"	"5.63"	"348.06"	"7.66"	"1"	"2"	"protein metabolism;other metabolic processes;stress response"	"ER/Golgi;other cell component"	"other molecular function"	"Pf06427, Pf18400, Pf18401, Pf18402, Pf18403, Pf18404"	"56886"	"ENSG00000136731"	"UGGT1"	"hsa:56886; Q53QP2; Q53SL3; Q8IW30; Q9H8I4; Q9NYU2"	"IL-18 signaling pathway"	"ER Quality Control Compartment (ERQC)"	"2"	"0"	"26.1"	"23.0"	"23.6"	"19.9"	"25.1"	"23.1"	"33.4"	"27.1"	"56.2"	"85.6"	"108.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13439"	"Golgin subfamily A member 4 OS=Homo sapiens OX=9606 GN=GOLGA4 PE=1 SV=1"	"2"	"3"	"4"	"2"	"2230"	"261.0"	"5.39"	"319.28"	"7.65"	"1"	"3"	"cell organization and biogenesis;transport"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf01465"	"2803"	"ENSG00000144674"	"GOLGA4"	"F8W8Q7; hsa:2803; Q13270; Q13439; Q13654; Q14436; Q59EW8"	""	"Retrograde transport at the Trans-Golgi-Network; Signaling by membrane-tethered fusions of PDGFRA or PDGFRB"	"2"	"0"	"2.7"	"2.0"	"0.0"	"0.0"	"0.0"	"0.0"	"2.0"	"7.8"	"15.7"	"170.2"	"438.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14257"	"Reticulocalbin-2 OS=Homo sapiens OX=9606 GN=RCN2 PE=1 SV=1"	"8"	"2"	"4"	"2"	"317"	"36.9"	"4.40"	"619.95"	"7.64"	"2"	"2"	""	"ER/Golgi;nucleus"	"other molecular function"	"Pf13202"	"5955"	"ENSG00000117906"	"RCN2"	"A8MTG6; F8WCY5; hsa:5955; Q14257; Q53XN8"	""	""	"0"	"0"	"171.0"	"152.3"	"161.1"	"164.6"	"186.2"	"192.0"	"217.8"	"240.5"	"293.5"	"438.8"	"538.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14579"	"Coatomer subunit epsilon OS=Homo sapiens OX=9606 GN=COPE PE=1 SV=3"	"13"	"2"	"3"	"2"	"308"	"34.5"	"5.12"	"307.29"	"7.64"	"1"	"2"	"transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus"	"other molecular function"	"Pf04733"	"11316"	"ENSG00000105669"	"COPE"	"A6NE29; A6NKA3; hsa:11316; O14579; O76097; Q6IBB8; Q9UGP6"	""	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport"	"2"	"0"	"12.7"	"8.8"	"16.3"	"14.1"	"16.4"	"13.8"	"18.2"	"24.7"	"78.1"	"211.4"	"380.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95239"	"Chromosome-associated kinesin KIF4A OS=Homo sapiens OX=9606 GN=KIF4A PE=1 SV=3"	"3"	"3"	"5"	"3"	"1232"	"139.8"	"6.27"	"1131.20"	"7.62"	"3"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00225"	"24137"	"ENSG00000090889"	"KIF4A"	"B2R7V5; D3DVU4; hsa:24137; O95239; Q86TN3; Q86XX7; Q9NNY6; Q9NY24; Q9UMW3"	"Retinoblastoma gene in cancer"	"Recycling pathway of L1; COPI-dependent Golgi-to-ER retrograde traffic; MHC class II antigen presentation; Kinesins"	"5"	"0"	"75.2"	"61.8"	"75.4"	"65.1"	"78.6"	"68.4"	"86.6"	"111.4"	"335.6"	"628.5"	"822.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HAU5"	"Regulator of nonsense transcripts 2 OS=Homo sapiens OX=9606 GN=UPF2 PE=1 SV=1"	"3"	"3"	"6"	"3"	"1272"	"147.7"	"5.69"	"1041.44"	"7.62"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02854, Pf04050"	"26019"	"ENSG00000151461"	"UPF2"	"A6NLJ5; D3DRS0; hsa:26019; Q14BM1; Q5W0J4; Q8N8U1; Q9H1J2; Q9HAU5; Q9NWL1; Q9P2D9; Q9Y4M9"	""	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	"2"	"0"	"106.7"	"128.1"	"115.2"	"81.6"	"115.2"	"95.2"	"135.6"	"172.6"	"260.8"	"388.3"	"502.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NVZ3"	"Adaptin ear-binding coat-associated protein 2 OS=Homo sapiens OX=9606 GN=NECAP2 PE=1 SV=1"	"10"	"2"	"5"	"1"	"263"	"28.3"	"8.38"	"1091.62"	"7.61"	"2"	"1"	"transport"	"plasma membrane;other membranes"	""	"Pf07933"	"55707"	"ENSG00000157191"	"NECAP2"	"B4DY19; E9PGQ8; hsa:55707; Q5VSU4; Q5VSU5; Q9H7L1; Q9H8L1; Q9NVZ3"	""	"Cargo recognition for clathrin-mediated endocytosis"	"2"	"0"	"43.8"	"24.9"	"38.1"	"28.7"	"33.3"	"45.8"	"85.0"	"145.0"	"132.7"	"168.4"	"217.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75175"	"CCR4-NOT transcription complex subunit 3 OS=Homo sapiens OX=9606 GN=CNOT3 PE=1 SV=1"	"3"	"2"	"4"	"2"	"753"	"81.8"	"6.20"	"866.29"	"7.60"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf04065, Pf04153"	"4849"	"ENSG00000088038; ENSG00000273943; ENSG00000274176; ENSG00000274616; ENSG00000274941; ENSG00000275979; ENSG00000276082; ENSG00000277114; ENSG00000277600; ENSG00000277615"	"CNOT3"	"hsa:4849; O75175; Q9NZN7; Q9UF76"	""	"Deadenylation of mRNA; TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"	"2"	"0"	"38.2"	"47.8"	"59.3"	"49.5"	"51.7"	"54.3"	"74.3"	"108.1"	"195.8"	"667.1"	"1914.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UDY4"	"DnaJ homolog subfamily B member 4 OS=Homo sapiens OX=9606 GN=DNAJB4 PE=1 SV=1"	"9"	"2"	"4"	"1"	"337"	"37.8"	"8.50"	"714.79"	"7.60"	"2"	"2"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus"	"other molecular function"	"Pf00226, Pf01556"	"11080"	"ENSG00000162616"	"DNAJB4"	"B2R824; hsa:11080; Q13431; Q9UDY4"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"28.5"	"25.2"	"25.8"	"22.5"	"24.9"	"28.4"	"35.4"	"33.7"	"60.9"	"86.2"	"99.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15437"	"Protein transport protein Sec23B OS=Homo sapiens OX=9606 GN=SEC23B PE=1 SV=2"	"2"	"1"	"5"	"1"	"767"	"86.4"	"6.89"	"1246.94"	"7.59"	"1"	"1"	"cell organization and biogenesis;transport"	"other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00626, Pf04810, Pf04811, Pf04815, Pf08033"	"10483"	"ENSG00000101310"	"SEC23B"	"D3DW33; hsa:10483; Q15437; Q503A9; Q5W183; Q9BS15; Q9BSI2; Q9H1D7"	"Sterol regulatory element-binding proteins (SREBP) signaling"	""	"1"	"0"	"46.8"	"57.5"	"62.0"	"65.1"	"52.0"	"41.9"	"77.5"	"80.4"	"131.0"	"290.1"	"477.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15504"	"Nucleoporin NUP42 OS=Homo sapiens OX=9606 GN=NUP42 PE=1 SV=1"	"6"	"2"	"4"	"2"	"423"	"44.8"	"9.19"	"763.42"	"7.57"	"2"	"2"	"transport"	"other membranes;cytosol;nucleus"	"other molecular function"	""	"11097"	"ENSG00000136243"	"NUP42"	"A4D143; B4DP42; hsa:11097; O15504; Q49AE7; Q9BS49"	""	"HCMV Early Events; HCMV Late Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"28"	"0"	"149.5"	"143.2"	"149.3"	"142.9"	"166.3"	"171.0"	"169.5"	"186.3"	"253.0"	"477.5"	"726.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BWS9"	"Chitinase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHID1 PE=1 SV=1"	"6"	"3"	"5"	"3"	"393"	"44.9"	"8.63"	"1020.20"	"7.57"	"3"	"2"	"other metabolic processes;stress response;other biological processes"	"non-structural extracellular;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00704"	"66005"	"ENSG00000177830"	"CHID1"	"B3KWB0; hsa:66005; Q8NBM9; Q96CZ3; Q96S93; Q96SK0; Q9BWS9; Q9BY52"	""	"Platelet degranulation"	"1"	"0"	"394.9"	"357.4"	"296.1"	"309.3"	"381.2"	"371.3"	"459.6"	"604.7"	"739.8"	"1071.4"	"1078.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14562"	"Ubiquitin domain-containing protein UBFD1 OS=Homo sapiens OX=9606 GN=UBFD1 PE=1 SV=2"	"9"	"2"	"4"	"2"	"309"	"33.4"	"5.77"	"767.78"	"7.57"	"2"	"2"	""	""	""	"Pf00240"	"56061"	"ENSG00000103353"	"UBFD1"	"A8MW58; D3DWF2; hsa:56061; O14562"	""	""	"0"	"0"	"32.0"	"28.4"	"34.5"	"30.3"	"38.1"	"30.7"	"47.2"	"57.9"	"173.1"	"541.7"	"788.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y285"	"Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3"	"2"	"2"	"4"	"2"	"508"	"57.5"	"7.80"	"802.56"	"7.54"	"2"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01409, Pf18552, Pf18553, Pf18554"	"2193"	"ENSG00000179115"	"FARSA"	"B4E363; hsa:2193; Q9NSD8; Q9Y285; Q9Y4W8"	""	"Cytosolic tRNA aminoacylation"	"1"	"0"	"88.4"	"77.2"	"95.5"	"83.4"	"111.5"	"95.2"	"108.5"	"121.3"	"189.4"	"277.5"	"332.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H0E9"	"Bromodomain-containing protein 8 OS=Homo sapiens OX=9606 GN=BRD8 PE=1 SV=2"	"2"	"2"	"4"	"2"	"1235"	"135.3"	"4.60"	"834.97"	"7.53"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00439"	"10902"	"ENSG00000112983"	"BRD8"	"hsa:10902; O43178; Q15355; Q58AB0; Q59GN0; Q969M9; Q9H0E9"	""	"HATs acetylate histones"	"1"	"0"	"96.7"	"84.4"	"91.1"	"80.9"	"97.2"	"100.0"	"107.9"	"120.5"	"173.2"	"330.2"	"460.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16352"	"Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2"	"6"	"3"	"6"	"2"	"499"	"55.4"	"5.40"	"1049.35"	"7.52"	"3"	"2"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf00038, Pf04732"	"9118"	"ENSG00000148798"	"INA"	"B1AQK0; hsa:9118; Q16352; Q9BRC5"	""	""	"0"	"0"	"107.0"	"106.7"	"134.0"	"100.3"	"103.0"	"102.3"	"138.4"	"235.7"	"501.5"	"811.6"	"1117.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15164"	"Transcription intermediary factor 1-alpha OS=Homo sapiens OX=9606 GN=TRIM24 PE=1 SV=3"	"3"	"3"	"4"	"3"	"1050"	"116.8"	"7.11"	"337.05"	"7.51"	"1"	"3"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;kinase activity;other molecular function"	"Pf00439, Pf00628, Pf00643"	"8805"	"ENSG00000122779"	"TRIM24"	"A4D1R7; A4D1R8; hsa:8805; O15164; O95854"	""	"Signaling by BRAF and RAF1 fusions; Signaling by cytosolic FGFR1 fusion mutants; Signaling by FGFR1 in disease"	"3"	"0"	"65.8"	"68.9"	"89.4"	"75.8"	"87.2"	"73.7"	"82.4"	"101.4"	"152.2"	"266.9"	"413.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13884"	"Beta-1-syntrophin OS=Homo sapiens OX=9606 GN=SNTB1 PE=1 SV=3"	"8"	"3"	"4"	"3"	"538"	"58.0"	"8.63"	"587.28"	"7.50"	"2"	"2"	"other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00169, Pf00595, Pf18012"	"6641"	"ENSG00000172164"	"SNTB1"	"A8K9E0; hsa:6641; O14912; Q13884; Q4KMG8"	"IL-18 signaling pathway; 13q12.12 copy number variation"	""	"2"	"0"	"20.8"	"15.4"	"22.1"	"13.1"	"17.1"	"18.0"	"22.3"	"32.5"	"60.6"	"153.3"	"185.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IVM0"	"Coiled-coil domain-containing protein 50 OS=Homo sapiens OX=9606 GN=CCDC50 PE=1 SV=1"	"7"	"2"	"4"	"2"	"306"	"35.8"	"6.65"	"863.78"	"7.50"	"2"	"2"	"other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf15295"	"152137"	"ENSG00000152492"	"CCDC50"	"hsa:152137; Q86VH7; Q8IVM0"	""	""	"0"	"0"	"165.6"	"145.7"	"155.9"	"149.6"	"159.7"	"162.4"	"201.8"	"256.4"	"751.9"	"1093.1"	"1404.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60953"	"Cell division control protein 42 homolog OS=Homo sapiens OX=9606 GN=CDC42 PE=1 SV=2"	"6"	"1"	"4"	"1"	"191"	"21.2"	"6.55"	"937.46"	"7.49"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00071"	"998"	"ENSG00000070831"	"CDC42"	"hsa:998; P21181; P25763; P60953; Q7L8R5; Q9UDI2"	"Androgen receptor signaling pathway; Target of rapamycin signaling; Integrin-mediated cell adhesion; RANKL/RANK signaling pathway; Leptin signaling pathway; Microtubule cytoskeleton regulation; Metastatic brain tumor; Pathogenic Escherichia coli infection; RalA downstream regulated genes; B cell receptor signaling pathway; AGE/RAGE pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Spinal cord injury; Focal adhesion; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Oxidative damage response; p38 MAPK signaling pathway; Ebola virus infection in host; Ras signaling; Pancreatic adenocarcinoma pathway; EGF/EGFR signaling pathway; Nonalcoholic fatty liver disease; Hippo signaling regulation pathways; 22q11.2 copy number variation syndrome; Gastrin signaling pathway; Regulation of actin cytoskeleton; G13 signaling pathway; Genetic causes of porto-sinusoidal vascular disease; 13q12.12 copy number variation; T-cell receptor signaling pathway; DNA damage response (only ATM dependent)"	"RHO GTPases Activate Formins; MAPK6/MAPK4 signaling; RHO GTPases activate IQGAPs; RAC1 GTPase cycle; RHOV GTPase cycle; RHOU GTPase cycle; VEGFA-VEGFR2 Pathway; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; EPHB-mediated forward signaling; Factors involved in megakaryocyte development and platelet production; CDC42 GTPase cycle; RHOQ GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOJ GTPase cycle; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; DCC mediated attractive signaling; GPVI-mediated activation cascade; Myogenesis; G beta:gamma signalling through CDC42; EGFR downregulation; RHO GTPases activate PAKs; Inactivation of CDC42 and RAC1; CD28 dependent Vav1 pathway; RHO GTPases activate KTN1"	"61"	"0"	"254.7"	"194.5"	"236.1"	"221.6"	"245.8"	"239.8"	"282.3"	"337.3"	"610.7"	"959.0"	"1256.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P32121"	"Beta-arrestin-2 OS=Homo sapiens OX=9606 GN=ARRB2 PE=1 SV=2"	"7"	"3"	"6"	"2"	"409"	"46.1"	"7.69"	"831.27"	"7.48"	"3"	"3"	"cell-cell signaling;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00339, Pf02752"	"409"	"ENSG00000141480"	"ARRB2"	"B4DLW0; B5B0C0; B7WPL3; D3DTK2; H0Y688; hsa:409; P32121; Q0Z8D3; Q2PP19; Q6ICT3; Q8N7Y2; Q9UEQ6"	"Corticotropin-releasing hormone signaling pathway; Complement system; Myometrial relaxation and contraction pathways; Wnt signaling pathway; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Hedgehog signaling pathway; Gastrin signaling pathway; Kisspeptin/kisspeptin receptor system in the ovary; GPR143 in melanocytes and retinal pigment epithelium cells; Calcium regulation in cardiac cells"	"Ub-specific processing proteases; Activation of SMO; Activated NOTCH1 Transmits Signal to the Nucleus; G alpha (s) signalling events; Signaling by BRAF and RAF1 fusions; Thrombin signalling through proteinase activated receptors (PARs); Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants"	"27"	"1"	"95.3"	"98.6"	"100.5"	"104.6"	"135.4"	"183.8"	"413.4"	"949.7"	"426.9"	"473.6"	"581.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9ULD4"	"Bromodomain and PHD finger-containing protein 3 OS=Homo sapiens OX=9606 GN=BRPF3 PE=1 SV=2"	"2"	"1"	"2"	"1"	"1205"	"135.7"	"6.58"	""	"7.48"	""	"1"	"cell organization and biogenesis;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00439, Pf00855, Pf10513, Pf13831, Pf13832"	"27154"	"ENSG00000096070"	"BRPF3"	"A6ND56; A6NJE2; B7ZLN5; E7EX85; hsa:27154; Q17RB6; Q5R3K8; Q9ULD4"	""	"HATs acetylate histones; Platelet degranulation ; Regulation of TP53 Activity through Acetylation"	"3"	"0"	"38.0"	"24.8"	"38.0"	"29.0"	"44.1"	"35.0"	"46.1"	"58.2"	"90.1"	"118.6"	"149.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P32780"	"General transcription factor IIH subunit 1 OS=Homo sapiens OX=9606 GN=GTF2H1 PE=1 SV=1"	"7"	"3"	"5"	"3"	"548"	"62.0"	"8.66"	"1302.83"	"7.47"	"3"	"2"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus"	"other molecular function"	"Pf03909, Pf08567"	"2965"	"ENSG00000110768; ENSG00000288114"	"GTF2H1"	"B3KXE0; D3DQY2; hsa:2965; P32780; Q6I9Y7; Q9H5K5; Q9NQD9"	"Eukaryotic transcription initiation; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Dual Incision in GG-NER"	"33"	"0"	"25.8"	"32.0"	"35.6"	"28.3"	"34.0"	"39.9"	"54.4"	"141.3"	"316.3"	"651.8"	"937.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6UB35"	"Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1"	"3"	"2"	"4"	"2"	"978"	"105.7"	"8.06"	"878.20"	"7.47"	"2"	"2"	"other metabolic processes;developmental processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf00763, Pf01268, Pf02882"	"25902"	"ENSG00000120254"	"MTHFD1L"	"hsa:25902; Q2TBF3; Q6UB35; Q8WVW0; Q96HG8; Q9H789; Q9UFU8"	"One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways"	"Metabolism of folate and pterines"	"3"	"0"	"115.1"	"109.9"	"105.9"	"106.8"	"127.7"	"122.2"	"134.5"	"148.4"	"298.4"	"742.8"	"938.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09234"	"U1 small nuclear ribonucleoprotein C OS=Homo sapiens OX=9606 GN=SNRPC PE=1 SV=1"	"13"	"2"	"4"	"2"	"159"	"17.4"	"9.67"	"785.25"	"7.46"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf06220"	"6631"	"ENSG00000124562"	"SNRPC"	"hsa:6631; P09234; Q5TAL3"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"177.2"	"117.3"	"166.7"	"127.8"	"164.2"	"163.1"	"181.6"	"259.3"	"343.4"	"722.5"	"1172.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52739"	"Zinc finger protein 131 OS=Homo sapiens OX=9606 GN=ZNF131 PE=1 SV=2"	"4"	"2"	"4"	"2"	"623"	"71.4"	"5.19"	"713.10"	"7.46"	"2"	"2"	"other biological processes"	"cytoskeleton;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00651, Pf12874"	"7690"	"ENSG00000172262"	"ZNF131"	"B4DRL3; hsa:7690; P52739; Q6PIF0"	""	"SUMOylation of transcription cofactors"	"1"	"0"	"15.6"	"15.2"	"19.9"	"19.8"	"21.4"	"21.7"	"25.0"	"32.6"	"86.3"	"197.5"	"252.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60343"	"TBC1 domain family member 4 OS=Homo sapiens OX=9606 GN=TBC1D4 PE=1 SV=2"	"3"	"3"	"5"	"3"	"1298"	"146.5"	"7.01"	"1045.44"	"7.46"	"3"	"2"	"transport;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity"	"Pf00566, Pf00640, Pf11830"	"9882"	"ENSG00000136111"	"TBC1D4"	"A7E2X8; B4DU25; B4E235; B6ETN8; B6ETN9; hsa:9882; O60343; Q5W0B9; Q68D14"	"Ciliary landscape; Thyroid hormones production and peripheral downstream signaling effects; Insulin signaling"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"	"4"	"0"	"67.5"	"52.2"	"69.3"	"51.5"	"58.2"	"53.3"	"63.0"	"64.7"	"158.7"	"556.6"	"1036.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5L4"	"Mitochondrial import inner membrane translocase subunit Tim13 OS=Homo sapiens OX=9606 GN=TIMM13 PE=1 SV=1"	"12"	"1"	"4"	"1"	"95"	"10.5"	"8.18"	"625.96"	"7.45"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf02953"	"26517"	"ENSG00000099800"	"TIMM13"	"hsa:26517; P62206; Q9UHL8; Q9WTL1; Q9Y5L4"	""	"Mitochondrial protein import"	"1"	"0"	"37.0"	"43.5"	"50.2"	"31.4"	"46.8"	"48.6"	"62.6"	"113.4"	"226.1"	"473.4"	"950.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12899"	"Tripartite motif-containing protein 26 OS=Homo sapiens OX=9606 GN=TRIM26 PE=1 SV=1"	"5"	"2"	"4"	"2"	"539"	"62.1"	"5.03"	"871.34"	"7.45"	"2"	"2"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00622, Pf00643, Pf13765, Pf15227"	"7726"	"ENSG00000137313; ENSG00000226060; ENSG00000228881; ENSG00000230230; ENSG00000231002; ENSG00000231641; ENSG00000234046; ENSG00000234127"	"TRIM26"	"A6NG96; hsa:7726; Q12899; Q5SRL2"	""	"Interferon gamma signaling"	"1"	"0"	"30.8"	"28.8"	"35.8"	"36.0"	"29.2"	"26.0"	"33.2"	"55.2"	"67.2"	"103.0"	"148.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16718"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 OS=Homo sapiens OX=9606 GN=NDUFA5 PE=1 SV=3"	"24"	"2"	"4"	"2"	"116"	"13.5"	"5.99"	"700.15"	"7.44"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf04716"	"4698"	"ENSG00000128609"	"NDUFA5"	"B2RD98; hsa:4698; Q16718; Q5H9R2; Q6IRX7"	"Electron transport chain: OXPHOS system in mitochondria; Ciliary landscape; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis; RHOG GTPase cycle"	"7"	"0"	"49.1"	"50.2"	"56.9"	"49.6"	"56.0"	"60.4"	"65.5"	"76.7"	"238.2"	"410.6"	"551.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H223"	"EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1"	"4"	"2"	"4"	"2"	"541"	"61.1"	"6.76"	"608.49"	"7.44"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00350, Pf12763, Pf16880, Pf18150"	"30844"	"ENSG00000103966"	"EHD4"	"hsa:30844; Q9H223; Q9HAR1; Q9NZN2"	""	""	"0"	"0"	"19.6"	"23.2"	"30.4"	"21.5"	"28.2"	"34.6"	"39.5"	"78.6"	"305.9"	"491.7"	"520.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86WG5"	"Myotubularin-related protein 13 OS=Homo sapiens OX=9606 GN=SBF2 PE=1 SV=1"	"2"	"3"	"5"	"3"	"1849"	"208.3"	"7.06"	"1108.59"	"7.44"	"3"	"2"	"other metabolic processes;developmental processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf02141, Pf02893, Pf03456, Pf06602, Pf12335"	"81846"	"ENSG00000133812"	"SBF2"	"hsa:81846; Q3MJF0; Q68DQ3; Q6P459; Q6PJD1; Q7Z325; Q7Z621; Q86VE2; Q86WG5; Q96FE2; Q9C097"	"Intracellular trafficking proteins involved in CMT neuropathy"	"Synthesis of PIPs at the plasma membrane; RAB GEFs exchange GTP for GDP on RABs"	"3"	"0"	"87.8"	"60.1"	"91.0"	"89.6"	"103.9"	"154.7"	"217.3"	"381.9"	"650.3"	"874.8"	"1006.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UPY3"	"Endoribonuclease Dicer OS=Homo sapiens OX=9606 GN=DICER1 PE=1 SV=3"	"2"	"2"	"3"	"2"	"1922"	"218.5"	"5.68"	"316.97"	"7.44"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00271, Pf00636, Pf02170, Pf03368, Pf04851"	"23405"	"ENSG00000100697"	"DICER1"	"A7E2D3; B3KRG4; E0AD28; hsa:23405; O95943; Q9UPY3; Q9UQ02"	"miRNA biogenesis; exRNA mechanism of action and biogenesis; Hypoxia-mediated EMT and stemness; mRNA processing; Fragile X syndrome; Influence of laminopathies on Wnt signaling; Overlap between signal transduction pathways contributing to LMNA laminopathies"	"MicroRNA (miRNA) biogenesis; Small interfering RNA (siRNA) biogenesis; tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis"	"10"	"0"	"17.2"	"14.6"	"16.7"	"18.2"	"16.3"	"16.5"	"17.4"	"27.6"	"45.3"	"83.5"	"115.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13489"	"Ribonuclease inhibitor OS=Homo sapiens OX=9606 GN=RNH1 PE=1 SV=2"	"5"	"2"	"4"	"2"	"461"	"49.9"	"4.82"	"678.68"	"7.44"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf13516, Pf18779"	"6050"	"ENSG00000023191; ENSG00000276230"	"RNH1"	"hsa:6050; P13489; Q8IZK8; Q96FD7; Q9BQ80; Q9UDK6"	""	""	"0"	"0"	"21.9"	"26.9"	"30.6"	"25.4"	"25.2"	"20.5"	"33.2"	"35.9"	"61.7"	"122.7"	"162.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16204"	"Coiled-coil domain-containing protein 6 OS=Homo sapiens OX=9606 GN=CCDC6 PE=1 SV=2"	"6"	"2"	"4"	"2"	"474"	"53.3"	"7.34"	"953.24"	"7.43"	"2"	"2"	"cell organization and biogenesis"	"cytosol;cytoskeleton"	"cytoskeletal activity;other molecular function"	"Pf09755"	"8030"	"ENSG00000108091"	"CCDC6"	"hsa:8030; Q15250; Q16204; Q6GSG7"	"Retinoblastoma gene in cancer; Mesodermal commitment pathway; 16p11.2 proximal deletion syndrome"	""	"3"	"0"	"111.6"	"89.4"	"96.9"	"90.2"	"106.9"	"97.7"	"121.1"	"161.2"	"341.3"	"621.2"	"851.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q02818"	"Nucleobindin-1 OS=Homo sapiens OX=9606 GN=NUCB1 PE=1 SV=4"	"6"	"2"	"4"	"2"	"461"	"53.8"	"5.25"	"885.54"	"7.42"	"2"	"2"	"signal transduction"	"ER/Golgi"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf13499"	"4924"	"ENSG00000104805"	"NUCB1"	"B2RD64; hsa:4924; Q02818; Q15838; Q7Z4J7; Q9BUR1"	""	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation"	"2"	"0"	"149.9"	"143.6"	"172.1"	"139.1"	"171.0"	"170.6"	"186.2"	"201.9"	"237.1"	"321.9"	"383.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQA1"	"Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1"	"9"	"3"	"6"	"3"	"342"	"36.7"	"5.17"	"825.04"	"7.41"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400"	"79084"	"ENSG00000116455"	"WDR77"	"B3KMW6; B4DP38; hsa:79084; Q3LID2; Q53FU2; Q6JZZ5; Q96GK4; Q9BQA1; Q9BWY3"	""	"snRNP Assembly; RMTs methylate histone arginines"	"2"	"0"	"50.0"	"52.2"	"74.3"	"64.1"	"67.1"	"58.8"	"79.9"	"94.3"	"176.5"	"412.1"	"734.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3T9"	"Nucleolar complex protein 2 homolog OS=Homo sapiens OX=9606 GN=NOC2L PE=1 SV=4"	"5"	"3"	"5"	"3"	"749"	"84.9"	"5.62"	"1199.60"	"7.39"	"3"	"2"	"cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf03715"	"26155"	"ENSG00000188976"	"NOC2L"	"hsa:26155; Q5SVA3; Q9BTN6; Q9Y3T9"	"1p36 copy number variation syndrome"	"Regulation of TP53 Activity through Phosphorylation"	"2"	"0"	"172.5"	"170.8"	"182.2"	"183.2"	"181.5"	"185.1"	"220.6"	"229.6"	"314.1"	"467.4"	"737.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15434"	"RNA-binding motif, single-stranded-interacting protein 2 OS=Homo sapiens OX=9606 GN=RBMS2 PE=1 SV=1"	"6"	"3"	"6"	"1"	"407"	"43.9"	"9.07"	"830.49"	"7.39"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"5939"	"ENSG00000076067"	"RBMS2"	"hsa:5939; Q15434"	""	""	"0"	"2"	"356.9"	"344.5"	"372.4"	"317.3"	"356.7"	"310.5"	"419.4"	"528.0"	"598.7"	"845.5"	"1152.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62277"	"40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2"	"27"	"4"	"6"	"4"	"151"	"17.2"	"10.54"	"1112.84"	"7.39"	"3"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00312, Pf08069"	"6207"	"ENSG00000110700"	"RPS13"	"B2R549; hsa:6207; P19116; P62277; Q02546; Q29200; Q498Y0"	"Cytoplasmic ribosomal proteins"	"Major pathway of rRNA processing in the nucleolus and cytosol; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"287.3"	"325.2"	"257.3"	"198.7"	"238.2"	"270.0"	"341.8"	"464.9"	"586.4"	"998.1"	"1429.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23919"	"Thymidylate kinase OS=Homo sapiens OX=9606 GN=DTYMK PE=1 SV=4"	"9"	"2"	"4"	"2"	"212"	"23.8"	"8.27"	"789.10"	"7.38"	"2"	"2"	"other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf02223"	"1841"	"ENSG00000168393"	"DTYMK"	"B7ZW70; hsa:1841; P23919; Q6FGX1; Q9BUX4"	"Pyrimidine metabolism; 2q37 copy number variation syndrome"	"Interconversion of nucleotide di- and triphosphates"	"3"	"0"	"105.6"	"113.7"	"115.2"	"82.7"	"117.2"	"127.7"	"155.2"	"200.6"	"331.3"	"602.0"	"853.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P29558"	"RNA-binding motif, single-stranded-interacting protein 1 OS=Homo sapiens OX=9606 GN=RBMS1 PE=1 SV=3"	"6"	"3"	"7"	"1"	"406"	"44.5"	"8.79"	"1086.38"	"7.37"	"3"	"3"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"5937"	"ENSG00000153250"	"RBMS1"	"hsa:5937; P29558; Q14869; Q15433; Q53P46; Q53QX8; Q53RG6; Q8WV20"	""	""	"0"	"0"	"273.0"	"256.1"	"279.7"	"211.5"	"251.8"	"253.2"	"289.4"	"329.2"	"369.5"	"625.2"	"832.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5X3"	"Sorting nexin-5 OS=Homo sapiens OX=9606 GN=SNX5 PE=1 SV=1"	"5"	"2"	"3"	"1"	"404"	"46.8"	"6.76"	"629.19"	"7.36"	"1"	"2"	"protein metabolism;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00787, Pf09325"	"27131"	"ENSG00000089006"	"SNX5"	"B7ZKN3; D3DW26; hsa:27131; Q52LC4; Q7KZN0; Q9BWP0; Q9Y5X3"	""	"Golgi Associated Vesicle Biogenesis"	"1"	"0"	"9.0"	"6.4"	"9.8"	"7.4"	"11.5"	"7.3"	"13.4"	"12.9"	"32.2"	"120.2"	"227.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P2T1"	"GMP reductase 2 OS=Homo sapiens OX=9606 GN=GMPR2 PE=1 SV=1"	"6"	"2"	"3"	"1"	"348"	"37.9"	"7.23"	"348.22"	"7.36"	"1"	"2"	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00478"	"51292"	"ENSG00000100938; ENSG00000284752"	"GMPR2"	"D3DS66; hsa:51292; Q567T0; Q6IAJ8; Q86T14; Q9P2T1"	""	"Purine salvage"	"1"	"1"	"43.7"	"44.1"	"56.6"	"48.5"	"55.6"	"46.4"	"89.6"	"317.0"	"955.6"	"2179.7"	"3703.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9C005"	"Protein dpy-30 homolog OS=Homo sapiens OX=9606 GN=DPY30 PE=1 SV=1"	"27"	"3"	"5"	"3"	"99"	"11.2"	"4.88"	"769.19"	"7.35"	"2"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport"	"ER/Golgi;nucleus"	"other molecular function"	"Pf05186"	"84661"	"ENSG00000162961"	"DPY30"	"D6W578; hsa:84661; Q9C005"	"Kleefstra syndrome"	"Activation of anterior HOX genes in hindbrain development during early embryogenesis; PKMTs methylate histone lysines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Formation of WDR5-containing histone-modifying complexes"	"5"	"0"	"62.4"	"56.1"	"74.6"	"66.3"	"65.2"	"78.6"	"74.0"	"106.2"	"258.6"	"698.1"	"1162.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IYB3"	"Serine/arginine repetitive matrix protein 1 OS=Homo sapiens OX=9606 GN=SRRM1 PE=1 SV=2"	"5"	"4"	"6"	"4"	"904"	"102.3"	"11.84"	"1845.58"	"7.34"	"4"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity"	"Pf01480"	"10250"	"ENSG00000133226"	"SRRM1"	"hsa:10250; O60585; Q5VVN4; Q8IYB3"	"mRNA processing"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA Splicing - Major Pathway; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle"	"7"	"0"	"167.3"	"111.9"	"146.5"	"141.4"	"153.2"	"152.4"	"181.1"	"209.2"	"578.0"	"1315.4"	"2185.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86UK7"	"E3 ubiquitin-protein ligase ZNF598 OS=Homo sapiens OX=9606 GN=ZNF598 PE=1 SV=1"	"4"	"2"	"3"	"2"	"904"	"98.6"	"8.40"	"418.03"	"7.34"	"1"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus"	"enzyme regulator activity;translation activity;other molecular function"	""	"90850"	""	"ZNF598"	"hsa:90850; Q86UK7; Q8IW49; Q8N3D9; Q96FG3; Q9H7J3"	""	""	"0"	"0"	"29.3"	"27.1"	"38.9"	"28.9"	"37.9"	"37.3"	"35.9"	"36.1"	"50.9"	"75.1"	"95.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3C1"	"Nucleolar protein 16 OS=Homo sapiens OX=9606 GN=NOP16 PE=1 SV=2"	"25"	"3"	"5"	"3"	"178"	"21.2"	"9.94"	"1412.48"	"7.34"	"3"	"2"	"other biological processes"	"nucleus;other cell component"	""	"Pf09420"	"51491"	"ENSG00000048162"	"NOP16"	"B4DV13; D6RGD3; hsa:51491; Q05D05; Q6IAI6; Q6PIM0; Q8IXL5; Q9Y3C1"	"5q35 copy number variation"	""	"1"	"0"	"164.9"	"159.6"	"169.0"	"134.7"	"170.0"	"183.9"	"185.7"	"213.3"	"381.6"	"601.4"	"778.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O96019"	"Actin-like protein 6A OS=Homo sapiens OX=9606 GN=ACTL6A PE=1 SV=1"	"6"	"2"	"4"	"2"	"429"	"47.4"	"5.60"	"798.60"	"7.33"	"2"	"2"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00022"	"86"	"ENSG00000136518"	"ACTL6A"	"B3KMN1; D3DNR9; hsa:86; O96019; Q8TAE5; Q9BVS8; Q9H0W6"	"Androgen receptor network in prostate cancer; Gastric cancer network 1; Tumor suppressor activity of SMARCB1; Thermogenesis; Kleefstra syndrome"	"UCH proteinases; RMTs methylate histone arginines; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; HATs acetylate histones; DNA Damage Recognition in GG-NER"	"10"	"0"	"127.2"	"133.4"	"144.9"	"143.3"	"176.3"	"153.4"	"163.6"	"192.0"	"269.3"	"495.6"	"904.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60282"	"Kinesin heavy chain isoform 5C OS=Homo sapiens OX=9606 GN=KIF5C PE=1 SV=1"	"3"	"2"	"4"	"1"	"957"	"109.4"	"6.19"	"720.85"	"7.31"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225"	"3800"	"ENSG00000168280"	"KIF5C"	"hsa:3800; O60282; O95079; Q2YDC5"	"Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Insulin processing"	"3"	"0"	"3.4"	"6.1"	"8.5"	"2.8"	"7.6"	"2.3"	"5.3"	"7.8"	"19.7"	"51.7"	"59.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBK8"	"Methionine synthase reductase OS=Homo sapiens OX=9606 GN=MTRR PE=1 SV=4"	"3"	"2"	"3"	"2"	"698"	"77.6"	"6.49"	"369.38"	"7.30"	"1"	"2"	"DNA metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus"	"other molecular function"	"Pf00175, Pf00258, Pf00667"	"4552"	"ENSG00000124275"	"MTRR"	"hsa:4552; O60471; Q32MA9; Q7Z4M8; Q9UBK8"	"Vitamin B12 metabolism; Folate metabolism; One-carbon metabolism; Male infertility"	"Methylation; Cobalamin (Cbl) metabolism; Sulfur amino acid metabolism; Defective MTRR causes HMAE; Defective MTR causes HMAG"	"9"	"0"	"7.3"	"6.3"	"4.3"	"5.8"	"4.5"	"5.5"	"6.7"	"14.5"	"50.6"	"155.4"	"310.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6DN90"	"IQ motif and SEC7 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=IQSEC1 PE=1 SV=1"	"3"	"2"	"4"	"2"	"963"	"108.2"	"6.93"	"901.45"	"7.27"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf01369, Pf16453"	"9922"	"ENSG00000144711"	"IQSEC1"	"A0A087WWK8; hsa:9922; O94863; Q6DN90; Q96D85"	"EGF/EGFR signaling pathway"	""	"1"	"0"	"81.2"	"65.2"	"82.5"	"80.7"	"92.1"	"93.3"	"107.8"	"144.8"	"337.9"	"346.0"	"413.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19174"	"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 OS=Homo sapiens OX=9606 GN=PLCG1 PE=1 SV=1"	"2"	"2"	"3"	"2"	"1290"	"148.4"	"6.05"	"510.74"	"7.26"	"1"	"2"	"other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00017, Pf00018, Pf00168, Pf00387, Pf00388"	"5335"	"ENSG00000124181"	"PLCG1"	"B7ZLY7; B9EGH4; E1P5W4; hsa:5335; P19174; Q2V575"	"Angiogenesis; IL-1 signaling pathway; RANKL/RANK signaling pathway; Leptin signaling pathway; Glioblastoma signaling pathways; B cell receptor signaling pathway; Corticotropin-releasing hormone signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; PDGF pathway; Primary focal segmental glomerulosclerosis (FSGS); T cell receptor and co-stimulatory signaling; Myometrial relaxation and contraction pathways; Kit receptor signaling pathway; MFAP5-mediated ovarian cancer cell motility and invasiveness; BDNF-TrkB signaling; Physico-chemical features and toxicity-associated pathways; T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection; VEGFA-VEGFR2 signaling; GPR40 pathway; Ras signaling; Non-small cell lung cancer; EGF/EGFR signaling pathway; Resistin as a regulator of inflammation; Fragile X syndrome; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Gastrin signaling pathway; IL-18 signaling pathway; EGFR tyrosine kinase inhibitor resistance; mBDNF and proBDNF regulation of GABA neurotransmission; Modulators of TCR signaling and T cell activation; CCL18 signaling pathway; Th17 cell differentiation pathway; GDNF signaling; A network map of Macrophage-stimulating protein (MSP) signaling; 4p16.3 copy number variation; 5q35 copy number variation; ErbB signaling pathway; T-cell receptor signaling pathway"	"ISG15 antiviral mechanism; Role of phospholipids in phagocytosis; FCERI mediated MAPK activation; FCERI mediated Ca+2 mobilization; FCGR3A-mediated IL10 synthesis; Generation of second messenger molecules; Signaling by ALK fusions and activated point mutants; RET signaling; Downstream signal transduction; Signaling by ALK; DAP12 signaling; Signaling by ERBB2 KD Mutants; Signaling by ERBB2 TMD/JMD mutants; EGFR interacts with phospholipase C-gamma; Signaling by FGFR1 in disease; Synthesis of IP3 and IP4 in the cytosol; Phospholipase C-mediated cascade: FGFR1; Phospholipase C-mediated cascade; FGFR2; Signaling by FGFR2 in disease; VEGFR2 mediated cell proliferation; Phospholipase C-mediated cascade; FGFR3; Phospholipase C-mediated cascade; FGFR4; Signaling by FGFR3 in disease; DAG and IP3 signaling; Erythropoietin activates Phospholipase C gamma (PLCG); Role of second messengers in netrin-1 signaling; Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; PLCG1 events in ERBB2 signaling; Constitutive Signaling by EGFRvIII; Signaling by ERBB2 ECD mutants; Signaling by FGFR4 in disease; PLC-gamma1 signalling; PECAM1 interactions; Activated NTRK2 signals through PLCG1; Activated NTRK3 signals through PLCG1"	"73"	"0"	"13.6"	"13.5"	"17.6"	"16.1"	"19.1"	"17.2"	"21.5"	"34.4"	"65.1"	"255.7"	"274.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P1U0"	"DNA-directed RNA polymerase I subunit RPA12 OS=Homo sapiens OX=9606 GN=ZNRD1 PE=1 SV=1"	"19"	"2"	"3"	"2"	"126"	"13.9"	"5.06"	"292.30"	"7.26"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01096"	"30834"	"ENSG00000066379; ENSG00000206502; ENSG00000224859; ENSG00000233795; ENSG00000235176; ENSG00000235443; ENSG00000236808; ENSG00000236949"	"POLR1H"	"hsa:30834; Q9P1U0"	"Pyrimidine metabolism; 2q13 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"7"	"0"	"57.1"	"32.7"	"64.3"	"63.7"	"56.4"	"50.5"	"69.8"	"157.6"	"513.5"	"670.4"	"907.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBN7"	"Histone deacetylase 6 OS=Homo sapiens OX=9606 GN=HDAC6 PE=1 SV=2"	"2"	"2"	"4"	"2"	"1215"	"131.3"	"5.30"	"749.93"	"7.26"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00850, Pf02148"	"10013"	"ENSG00000094631"	"HDAC6"	"hsa:10013; O94975; Q6NT75; Q7L3E5; Q96CY0; Q9UBN7"	"Neural crest differentiation; Ectoderm differentiation; Ectoderm differentiation; Ethanol effects on histone modifications; 7q11.23 copy number variation syndrome"	"Cilium Assembly; Aggrephagy; Late endosomal microautophagy; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Transcriptional regulation by RUNX2; NOTCH1 Intracellular Domain Regulates Transcription; Notch-HLH transcription pathway; RUNX2 regulates osteoblast differentiation; Chaperone Mediated Autophagy; HSF1 activation"	"16"	"0"	"181.4"	"132.1"	"175.3"	"153.9"	"187.0"	"204.6"	"207.2"	"222.3"	"297.6"	"411.7"	"401.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49207"	"60S ribosomal protein L34 OS=Homo sapiens OX=9606 GN=RPL34 PE=1 SV=3"	"21"	"3"	"5"	"3"	"117"	"13.3"	"11.47"	"610.70"	"7.25"	"2"	"3"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01199"	"6164"	"ENSG00000109475"	"RPL34"	"hsa:6164; P49207; Q6FG66; Q9BUZ2"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"367.7"	"510.1"	"297.1"	"286.3"	"353.6"	"283.3"	"480.1"	"711.4"	"1121.3"	"2245.0"	"3497.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NTX5"	"Ethylmalonyl-CoA decarboxylase OS=Homo sapiens OX=9606 GN=ECHDC1 PE=1 SV=2"	"8"	"2"	"4"	"2"	"307"	"33.7"	"8.21"	"654.10"	"7.25"	"2"	"2"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf00378"	"55862"	"ENSG00000093144"	"ECHDC1"	"A6NFJ5; B7Z8S0; E9PEN7; E9PR31; F8W851; hsa:55862; Q5TEF6; Q5TEF7; Q5TEG0; Q5TEG4; Q9NTX5; Q9NZ30; V9HW18"	"Fatty acid biosynthesis"	""	"1"	"0"	"33.8"	"29.2"	"37.2"	"34.7"	"32.4"	"36.8"	"61.0"	"80.7"	"231.6"	"371.0"	"562.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96FF9"	"Sororin OS=Homo sapiens OX=9606 GN=CDCA5 PE=1 SV=1"	"9"	"2"	"6"	"2"	"252"	"27.6"	"9.61"	"853.05"	"7.22"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf09666"	"113130"	"ENSG00000146670"	"CDCA5"	"A8K625; hsa:113130; Q96FF9"	""	"Resolution of Sister Chromatid Cohesion; Separation of Sister Chromatids; Establishment of Sister Chromatid Cohesion"	"3"	"0"	"630.4"	"508.9"	"624.0"	"515.3"	"541.1"	"579.4"	"692.5"	"671.9"	"803.8"	"979.8"	"1160.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15334"	"Lethal(2) giant larvae protein homolog 1 OS=Homo sapiens OX=9606 GN=LLGL1 PE=1 SV=3"	"2"	"2"	"4"	"2"	"1064"	"115.3"	"6.29"	"716.78"	"7.21"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00400, Pf08366"	"3996"	"ENSG00000131899; ENSG00000284137"	"LLGL1"	"A7MBM7; hsa:3996; O00188; Q15334; Q58F11; Q86UK6"	"Smith-Magenis and Potocki-Lupski syndrome copy number variation"	""	"1"	"0"	"27.8"	"49.9"	"35.0"	"31.0"	"32.7"	"33.3"	"42.9"	"55.1"	"186.1"	"380.2"	"415.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46781"	"40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3"	"20"	"5"	"7"	"5"	"194"	"22.6"	"10.65"	"1392.31"	"7.21"	"4"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00163, Pf01479"	"6203"	"ENSG00000170889; ENSG00000274005; ENSG00000274626; ENSG00000274646; ENSG00000274950; ENSG00000275323; ENSG00000277079; ENSG00000277359; ENSG00000278081; ENSG00000278270"	"RPS9"	"A9C4C1; hsa:6203; P46781; Q4QRK7; Q9BVZ0"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"20"	"0"	"472.7"	"511.1"	"452.0"	"360.5"	"440.7"	"455.2"	"584.6"	"753.3"	"1307.4"	"2501.8"	"3617.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05386"	"60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1"	"34"	"3"	"5"	"2"	"114"	"11.5"	"4.32"	"1095.48"	"7.20"	"3"	"2"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00428"	"6176"	"ENSG00000137818"	"RPLP1"	"A6NIB2; hsa:6176; P05386"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"125.4"	"153.0"	"181.2"	"119.4"	"137.4"	"132.8"	"175.2"	"262.6"	"534.1"	"884.6"	"1561.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9ULR0"	"Pre-mRNA-splicing factor ISY1 homolog OS=Homo sapiens OX=9606 GN=ISY1 PE=1 SV=3"	"13"	"3"	"5"	"3"	"285"	"33.0"	"5.17"	"1161.85"	"7.20"	"3"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf06246"	"100534599; 57461"	"ENSG00000240682"	"ISY1"	"hsa:100534599; hsa:57461; Q96IL2; Q9BT05; Q9ULR0"	""	"Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; mRNA Splicing - Major Pathway"	"5"	"0"	"178.9"	"167.9"	"217.1"	"194.2"	"214.1"	"189.1"	"232.5"	"267.1"	"367.6"	"754.6"	"1585.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14203"	"Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3"	"2"	"2"	"4"	"1"	"1278"	"141.6"	"5.81"	"822.36"	"7.19"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01302, Pf12455"	"1639"	"ENSG00000204843"	"DCTN1"	"A8MY36; B4DM45; E9PFS5; E9PGE1; G5E9H4; hsa:1639; O95296; Q14203; Q6IQ37; Q9BRM9; Q9UIU1; Q9UIU2"	""	"MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Signaling by ALK fusions and activated point mutants; XBP1(S) activates chaperone genes"	"6"	"0"	"12.8"	"10.9"	"11.5"	"16.8"	"13.7"	"14.0"	"17.6"	"21.1"	"30.9"	"60.7"	"104.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P20020"	"Plasma membrane calcium-transporting ATPase 1 OS=Homo sapiens OX=9606 GN=ATP2B1 PE=1 SV=4"	"2"	"2"	"2"	"2"	"1220"	"134.6"	"5.91"	""	"7.18"	""	"2"	"stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf00122, Pf00689, Pf00690, Pf00702, Pf12424, Pf13246"	"490"	"ENSG00000070961"	"ATP2B1"	"hsa:490; P20020; Q12992; Q12993; Q13819; Q13820; Q13821; Q16504; Q93082"	"Vitamin D receptor pathway; Splicing factor NOVA regulated synaptic proteins; Vitamin D-sensitive calcium signaling in depression; Calcium regulation in cardiac cells"	"Sensory processing of sound by inner hair cells of the cochlea; Ion homeostasis; Ion transport by P-type ATPases; Reduction of cytosolic Ca++ levels"	"8"	"0"	"29.4"	"22.7"	"30.9"	"29.0"	"23.8"	"32.0"	"36.0"	"39.9"	"144.1"	"496.4"	"817.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62487"	"DNA-directed RNA polymerase II subunit RPB7 OS=Homo sapiens OX=9606 GN=POLR2G PE=1 SV=1"	"19"	"2"	"3"	"2"	"172"	"19.3"	"5.54"	"317.42"	"7.17"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00575, Pf03876"	"5436"	"ENSG00000168002"	"POLR2G"	"B2R5C0; hsa:5436; P52433; P62487; Q2M1Z4"	"Pyrimidine metabolism; Eukaryotic transcription initiation"	"Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; mRNA Splicing - Major Pathway; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"43"	"0"	"12.2"	"13.2"	"10.3"	"11.3"	"9.7"	"14.2"	"17.5"	"21.6"	"34.1"	"57.5"	"65.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5TZA2"	"Rootletin OS=Homo sapiens OX=9606 GN=CROCC PE=1 SV=1"	"1"	"2"	"4"	"2"	"2017"	"228.4"	"5.50"	"802.14"	"7.17"	"2"	"2"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"33.6"	"35.4"	"38.3"	"16.6"	"36.2"	"45.5"	"48.5"	"78.3"	"103.9"	"179.7"	"275.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UIA9"	"Exportin-7 OS=Homo sapiens OX=9606 GN=XPO7 PE=1 SV=3"	"2"	"1"	"4"	"1"	"1087"	"123.8"	"6.32"	"897.76"	"7.16"	"1"	"1"	"transport"	"nucleus;other cell component"	"other molecular function"	"Pf03810"	"23039"	"ENSG00000130227"	"XPO7"	"hsa:23039; O94846; Q6PJK9; Q8NEK7; Q9UIA9"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19404"	"NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV2 PE=1 SV=2"	"10"	"2"	"3"	"2"	"249"	"27.4"	"8.06"	"297.07"	"7.15"	"1"	"2"	"other metabolic processes;transport;developmental processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf01257"	"4729"	"ENSG00000178127"	"NDUFV2"	"hsa:4729; P19404; Q9BV41"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"0.0"	"0.0"	"4.3"	"0.0"	"3.8"	"2.9"	"1.9"	"7.2"	"25.6"	"45.9"	"60.9"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75489"	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS3 PE=1 SV=1"	"16"	"3"	"5"	"3"	"264"	"30.2"	"7.50"	"1407.36"	"7.15"	"3"	"2"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion;nucleus"	"transporter activity;other molecular function"	"Pf00329"	"4722"	"ENSG00000213619; ENSG00000285387"	"NDUFS3"	"B2R9J1; B4DFM8; hsa:4722; O75489; Q9UNQ8"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"RHOG GTPase cycle; Complex I biogenesis"	"6"	"0"	"94.7"	"108.7"	"107.4"	"86.6"	"101.4"	"111.4"	"124.8"	"177.5"	"405.2"	"905.6"	"1165.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00268"	"Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2"	"2"	"2"	"4"	"2"	"1085"	"110.0"	"9.94"	"796.00"	"7.13"	"2"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf05236, Pf07531"	"6874"	"ENSG00000130699"	"TAF4"	"A6NGD9; hsa:6874; O00268; Q5TBP6; Q99721; Q9BR40; Q9BX42"	""	"RNA Polymerase II Pre-transcription Events; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; Regulation of TP53 Activity through Phosphorylation; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation"	"9"	"0"	"112.1"	"102.1"	"121.1"	"110.1"	"139.1"	"131.6"	"143.9"	"156.2"	"249.3"	"406.0"	"554.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NF91"	"Nesprin-1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=4"	"0"	"3"	"4"	"1"	"8797"	"1010.5"	"5.53"	"252.10"	"7.12"	"1"	"3"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00435, Pf10541"	"23345"	"ENSG00000131018"	"SYNE1"	"B3W695; E7EQI5; H0Y4C0; hsa:23345; O94890; Q3ZCV0; Q5JV19; Q5JV22; Q8N9P7; Q8NF91; Q8TCP1; Q8WWW6; Q8WWW7; Q8WXF6; Q96N17; Q9C0A7; Q9H525; Q9H526; Q9NS36; Q9NU50; Q9UJ06; Q9UJ07; Q9ULF8"	"Envelope proteins and their potential roles in EDMD physiopathology"	"Meiotic synapsis"	"2"	"1"	"72.9"	"66.5"	"112.4"	"81.3"	"85.6"	"84.7"	"93.5"	"115.4"	"286.8"	"806.5"	"1197.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5Q9"	"General transcription factor 3C polypeptide 3 OS=Homo sapiens OX=9606 GN=GTF3C3 PE=1 SV=1"	"3"	"2"	"4"	"2"	"886"	"101.2"	"5.07"	"747.67"	"7.12"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13181"	"9330"	"ENSG00000119041"	"GTF3C3"	"hsa:9330; Q4ZG48; Q86XJ8; Q8WX84; Q96B44; Q9H5I8; Q9NT97; Q9Y5Q9"	""	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter"	"3"	"0"	"125.3"	"95.1"	"124.9"	"106.2"	"131.2"	"119.9"	"139.7"	"154.4"	"224.1"	"504.0"	"771.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NY61"	"Protein AATF OS=Homo sapiens OX=9606 GN=AATF PE=1 SV=1"	"6"	"2"	"4"	"2"	"560"	"63.1"	"4.94"	"703.64"	"7.10"	"2"	"2"	"cell adhesion;stress response;developmental processes;other biological processes"	"ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf08164, Pf13339"	"26574"	"ENSG00000275700; ENSG00000276072"	"AATF"	"A6NCJ6; B3KQ26; hsa:26574; Q9NY61; Q9P0A4; Q9UNX5"	"17q12 copy number variation syndrome"	"NRAGE signals death through JNK"	"2"	"0"	"27.9"	"29.2"	"30.3"	"20.6"	"26.6"	"27.5"	"32.2"	"50.4"	"107.0"	"206.4"	"283.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A0FGR8"	"Extended synaptotagmin-2 OS=Homo sapiens OX=9606 GN=ESYT2 PE=1 SV=1"	"3"	"2"	"4"	"2"	"921"	"102.3"	"9.26"	"772.25"	"7.10"	"2"	"2"	"cell organization and biogenesis;transport"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00168, Pf17047"	"57488"	"ENSG00000117868"	"ESYT2"	"A0FGR8; A4D229; hsa:57488; Q69YJ2; Q6UKI4; Q6ZTU0; Q6ZVU1; Q9BQS0; Q9NW47; Q9ULJ2"	""	"Glycosphingolipid metabolism"	"1"	"0"	"31.5"	"30.1"	"43.7"	"48.1"	"69.6"	"110.0"	"148.1"	"213.5"	"369.3"	"334.8"	"332.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86X55"	"Histone-arginine methyltransferase CARM1 OS=Homo sapiens OX=9606 GN=CARM1 PE=1 SV=3"	"4"	"1"	"1"	"1"	"608"	"65.8"	"6.73"	""	"7.08"	""	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06325, Pf11531"	"10498"	"ENSG00000142453"	"CARM1"	"A6NN38; hsa:10498; Q86X55"	"Androgen receptor signaling pathway; Nitric oxide metabolism in cystic fibrosis"	"Estrogen-dependent gene expression; Cytoprotection by HMOX1; PPARA activates gene expression; RMTs methylate histone arginines; Transcriptional regulation of white adipocyte differentiation; Heme signaling; BMAL1:CLOCK,NPAS2 activates circadian gene expression; Transcriptional activation of mitochondrial biogenesis; Activation of gene expression by SREBF (SREBP); TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; RORA activates gene expression"	"15"	"0"	"19.8"	"15.8"	"19.4"	"19.8"	"24.4"	"15.4"	"26.6"	"40.2"	"72.3"	"106.3"	"137.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NWS0"	"PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1"	"11"	"3"	"5"	"3"	"290"	"32.3"	"5.14"	"1078.68"	"7.06"	"3"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf08190, Pf18201"	"55011"	"ENSG00000104872"	"PIH1D1"	"B4DGN7; B4E2X7; hsa:55011; Q9BVL0; Q9NWS0"	""	""	"0"	"0"	"59.7"	"58.9"	"91.0"	"82.8"	"87.1"	"87.6"	"103.9"	"136.6"	"524.3"	"863.6"	"989.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z392"	"Trafficking protein particle complex subunit 11 OS=Homo sapiens OX=9606 GN=TRAPPC11 PE=1 SV=2"	"5"	"4"	"5"	"4"	"1133"	"128.8"	"7.14"	"1526.58"	"7.06"	"3"	"2"	"cell organization and biogenesis;transport;other biological processes"	"cytosol;ER/Golgi;other cell component"	""	"Pf11817, Pf12742"	"60684"	"ENSG00000168538"	"TRAPPC11"	"A4QPB8; B2RCD6; hsa:60684; Q5U5I7; Q6FI73; Q7Z392; Q86T25; Q9H0L1; Q9H5K9; Q9H8Q1; Q9H9I7"	"Genes related to primary cilium development (based on CRISPR)"	"RAB GEFs exchange GTP for GDP on RABs"	"2"	"0"	"21.0"	"26.3"	"20.4"	"24.6"	"19.1"	"20.8"	"36.8"	"75.2"	"213.3"	"456.6"	"776.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15550"	"Lysine-specific demethylase 6A OS=Homo sapiens OX=9606 GN=KDM6A PE=1 SV=2"	"3"	"2"	"3"	"2"	"1401"	"154.1"	"7.44"	"517.65"	"7.06"	"1"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf02373, Pf13181, Pf13432"	"7403"	"ENSG00000147050"	"KDM6A"	"hsa:7403; O15550; Q52LL9; Q5JVQ7"	"Mesodermal commitment pathway; Mesodermal commitment pathway; Pathways affected in adenoid cystic carcinoma; Pleural mesothelioma; Kleefstra syndrome"	"Formation of WDR5-containing histone-modifying complexes; Activation of anterior HOX genes in hindbrain development during early embryogenesis; HDMs demethylate histones"	"8"	"0"	"28.9"	"31.1"	"33.6"	"26.6"	"33.1"	"37.6"	"43.3"	"43.2"	"94.2"	"173.6"	"210.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7L0Y3"	"tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2"	"6"	"2"	"4"	"2"	"403"	"47.3"	"9.36"	"651.62"	"7.05"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01746"	"54931"	"ENSG00000174173"	"TRMT10C"	"hsa:54931; Q7L0Y3; Q9NRG5; Q9NX54; Q9Y596"	""	"tRNA processing in the mitochondrion; tRNA modification in the mitochondrion; rRNA processing in the mitochondrion"	"3"	"0"	"55.1"	"59.7"	"74.9"	"58.1"	"63.0"	"55.9"	"87.8"	"112.1"	"197.2"	"376.3"	"431.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P18848"	"Cyclic AMP-dependent transcription factor ATF-4 OS=Homo sapiens OX=9606 GN=ATF4 PE=1 SV=3"	"5"	"2"	"4"	"2"	"351"	"38.6"	"4.96"	"815.74"	"7.04"	"2"	"2"	"cell-cell signaling;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00170"	"468"	"ENSG00000128272"	"ATF4"	"hsa:468; P18848; Q96AQ3; Q9UH31"	"Alzheimer's disease and miRNA effects; Myometrial relaxation and contraction pathways; Photodynamic therapy-induced unfolded protein response; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; mRNA, protein, and metabolite inducation pathway by cyclosporin A; PI3K-Akt signaling pathway; Nonalcoholic fatty liver disease; Joubert syndrome; Hepatitis B infection; Unfolded protein response; 7q11.23 copy number variation syndrome; Alzheimer's disease"	"NFE2L2 regulating anti-oxidant/detoxification enzymes; Response of EIF2AK1 (HRI) to heme deficiency; ATF4 activates genes in response to endoplasmic reticulum  stress; Response of EIF2AK4 (GCN2) to amino acid deficiency; ATF6 (ATF6-alpha) activates chaperone genes"	"20"	"0"	"274.4"	"284.9"	"262.1"	"240.2"	"294.4"	"256.7"	"303.7"	"371.3"	"398.0"	"509.7"	"600.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BW92"	"Threonine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=TARS2 PE=1 SV=1"	"5"	"3"	"5"	"3"	"718"	"81.0"	"7.30"	"850.58"	"7.03"	"3"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00587, Pf02824, Pf03129, Pf07973"	"80222"	"ENSG00000143374"	"TARS2"	"hsa:80222; Q53GW7; Q96I50; Q9BW92; Q9H9V2"	""	"Mitochondrial tRNA aminoacylation"	"1"	"0"	"102.1"	"99.0"	"131.3"	"98.7"	"128.9"	"124.1"	"149.9"	"198.2"	"500.4"	"943.4"	"1304.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5Q8"	"General transcription factor 3C polypeptide 5 OS=Homo sapiens OX=9606 GN=GTF3C5 PE=1 SV=2"	"5"	"2"	"4"	"2"	"519"	"59.5"	"6.90"	"816.87"	"6.99"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09734, Pf17682"	"9328"	"ENSG00000148308"	"GTF3C5"	"A6NI44; A6NJB9; hsa:9328; Q5T7U2; Q5T7U3; Q8N2U7; Q8N857; Q96GD9; Q9H4P2; Q9Y5Q8"	""	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter"	"3"	"0"	"53.6"	"34.3"	"56.8"	"44.3"	"48.8"	"60.5"	"59.6"	"65.5"	"124.9"	"244.6"	"374.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49588"	"Alanine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=AARS1 PE=1 SV=2"	"3"	"2"	"3"	"2"	"968"	"106.7"	"5.53"	"250.06"	"6.99"	"1"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;mitochondrion;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01411, Pf02272, Pf07973"	"16"	"ENSG00000090861"	"AARS1"	"A6NF14; B4DR45; hsa:16; P49588; Q53GV7; Q96FA0"	"IL-18 signaling pathway"	"Cytosolic tRNA aminoacylation"	"2"	"0"	"18.9"	"15.7"	"24.3"	"18.9"	"23.2"	"18.7"	"18.0"	"27.5"	"74.2"	"306.0"	"922.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P21127"	"Cyclin-dependent kinase 11B OS=Homo sapiens OX=9606 GN=CDK11B PE=1 SV=4"	"6"	"4"	"4"	"4"	"795"	"92.6"	"5.54"	"726.25"	"6.99"	"2"	"2"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"984"	"ENSG00000248333"	"CDK11B"	"B7ZVY7; hsa:984; J3KTL7; J3QR29; J3QR44; O95265; P21127; Q12817; Q12818; Q12819; Q12820; Q12822; Q8N530; Q9NZS5; Q9UBJ0; Q9UBQ1; Q9UBR0; Q9UNY2; Q9UP57; Q9UP58; Q9UP59"	"1p36 copy number variation syndrome"	"Recruitment of mitotic centrosome proteins and complexes"	"2"	"0"	"327.7"	"322.7"	"305.0"	"316.2"	"362.1"	"330.4"	"403.3"	"522.8"	"570.3"	"996.2"	"1580.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92558"	"Wiskott-Aldrich syndrome protein family member 1 OS=Homo sapiens OX=9606 GN=WASF1 PE=1 SV=1"	"8"	"3"	"4"	"3"	"559"	"61.6"	"6.46"	"687.14"	"6.95"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02205"	"8936"	"ENSG00000112290"	"WASF1"	"E1P5F2; hsa:8936; Q5SZK7; Q92558"	"VEGFA-VEGFR2 signaling; Regulation of actin cytoskeleton"	"VEGFA-VEGFR2 Pathway; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RAC1 GTPase cycle; RHO GTPases Activate WASPs and WAVEs; RAC3 GTPase cycle"	"8"	"0"	"64.1"	"61.2"	"71.8"	"69.2"	"67.9"	"67.0"	"99.4"	"134.1"	"307.4"	"477.6"	"591.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P53992"	"Protein transport protein Sec24C OS=Homo sapiens OX=9606 GN=SEC24C PE=1 SV=3"	"2"	"2"	"4"	"2"	"1094"	"118.2"	"7.06"	"689.78"	"6.95"	"2"	"2"	"cell organization and biogenesis;transport;developmental processes"	"other membranes;cytosol;ER/Golgi"	"other molecular function"	"Pf00626, Pf04810, Pf04811, Pf04815, Pf08033"	"9632"	"ENSG00000176986"	"SEC24C"	"B4DZT4; hsa:9632; P53992; Q8WV25"	"Sterol regulatory element-binding proteins (SREBP) signaling"	"COPII-mediated vesicle transport; MHC class II antigen presentation; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Cargo concentration in the ER; Regulation of cholesterol biosynthesis by SREBP (SREBF)"	"7"	"0"	"68.1"	"62.7"	"82.9"	"54.4"	"65.9"	"59.7"	"84.6"	"102.7"	"165.4"	"330.1"	"509.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P33316"	"Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=DUT PE=1 SV=4"	"15"	"3"	"5"	"3"	"252"	"26.5"	"9.36"	"887.91"	"6.95"	"3"	"2"	"DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;mitochondrion;nucleus"	"signal transduction activity or receptor binding;other molecular function"	"Pf00692"	"1854"	"ENSG00000128951"	"DUT"	"A8K650; B4DPR5; hsa:1854; O14785; P33316; Q16708; Q16860; Q6FHN1; Q6NSA3; Q96Q81"	"Pyrimidine metabolism"	""	"1"	"0"	"191.5"	"204.1"	"203.0"	"187.2"	"203.5"	"203.4"	"246.9"	"277.7"	"449.9"	"981.7"	"1563.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WXI9"	"Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1"	"4"	"2"	"3"	"2"	"593"	"65.2"	"9.70"	"381.25"	"6.94"	"1"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00320, Pf16563"	"57459"	"ENSG00000143614; ENSG00000261992"	"GATAD2B"	"D3DUZ2; hsa:57459; Q5VUR2; Q7LG68; Q8WXI9; Q9ULS0"	""	"HDACs deacetylate histones; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Potential therapeutics for SARS; Regulation of PTEN gene transcription; RNA Polymerase I Transcription Initiation; Regulation of TP53 Activity through Acetylation"	"6"	"0"	"147.2"	"129.0"	"159.7"	"140.8"	"145.9"	"154.7"	"196.4"	"223.6"	"302.3"	"497.9"	"631.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQ24"	"Zinc finger FYVE domain-containing protein 21 OS=Homo sapiens OX=9606 GN=ZFYVE21 PE=1 SV=1"	"15"	"2"	"3"	"2"	"234"	"26.5"	"8.41"	"427.99"	"6.94"	"1"	"2"	""	"other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01363, Pf16696"	"79038"	"ENSG00000100711"	"ZFYVE21"	"A8K3A4; hsa:79038; Q86T05; Q96LT1; Q9BQ24"	""	""	"0"	"0"	"15.0"	"15.4"	"14.9"	"11.0"	"14.7"	"18.5"	"16.8"	"28.0"	"43.4"	"63.5"	"77.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H8E8"	"Cysteine-rich protein 2-binding protein OS=Homo sapiens OX=9606 GN=KAT14 PE=1 SV=3"	"2"	"1"	"2"	"1"	"782"	"88.8"	"6.57"	"634.08"	"6.93"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf13673"	"57325"	"ENSG00000149474"	"KAT14"	"A2A2I5; hsa:57325; Q96GW6; Q96IH3; Q9H8E8; Q9HBF0; Q9UIY5"	""	"HATs acetylate histones; Formation of WDR5-containing histone-modifying complexes"	"2"	"0"	"3.9"	"3.9"	"3.4"	"4.5"	"4.9"	"5.8"	"5.1"	"12.2"	"10.9"	"29.1"	"38.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7L4I2"	"Arginine/serine-rich coiled-coil protein 2 OS=Homo sapiens OX=9606 GN=RSRC2 PE=1 SV=1"	"10"	"6"	"8"	"6"	"434"	"50.5"	"11.33"	"1794.95"	"6.93"	"6"	"2"	""	""	""	"Pf15477"	"65117"	"ENSG00000111011"	"RSRC2"	"hsa:65117; Q6N040; Q6NW16; Q7L4I2; Q9H864"	""	""	"0"	"0"	"1086.3"	"810.0"	"1158.7"	"1028.2"	"1075.1"	"1077.8"	"1195.6"	"1359.7"	"2273.9"	"2981.5"	"3852.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15651"	"High mobility group nucleosome-binding domain-containing protein 3 OS=Homo sapiens OX=9606 GN=HMGN3 PE=1 SV=2"	"27"	"2"	"3"	"2"	"99"	"10.7"	"9.66"	"288.82"	"6.92"	"1"	"2"	"cell organization and biogenesis"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01101"	"9324"	"ENSG00000118418"	"HMGN3"	"B2RD37; hsa:9324; Q15651; Q5HYD3; Q7RTT0; Q969M5; Q9BZT7"	""	""	"0"	"0"	"103.2"	"84.2"	"113.2"	"108.7"	"99.5"	"126.0"	"121.1"	"113.4"	"258.7"	"242.5"	"239.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P43897"	"Elongation factor Ts, mitochondrial OS=Homo sapiens OX=9606 GN=TSFM PE=1 SV=2"	"5"	"2"	"2"	"2"	"325"	"35.4"	"8.38"	""	"6.92"	""	"2"	"protein metabolism;other metabolic processes;other biological processes"	"mitochondrion;nucleus"	"nucleic acid binding activity"	"Pf00889"	"10102"	"ENSG00000123297"	"TSFM"	"B4E391; F5H2T7; hsa:10102; P43897; Q561V7; Q8TBC2; Q9UQK0"	""	"Mitochondrial translation elongation"	"1"	"0"	"45.6"	"45.2"	"64.3"	"48.9"	"58.9"	"55.0"	"65.4"	"75.1"	"373.7"	"1509.8"	"2347.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NRN9"	"rRNA N6-adenosine-methyltransferase METTL5 OS=Homo sapiens OX=9606 GN=METTL5 PE=1 SV=1"	"11"	"2"	"4"	"2"	"209"	"23.7"	"6.68"	"673.63"	"6.91"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05175"	"29081"	"ENSG00000138382"	"METTL5"	"D3DPC9; hsa:29081; Q9NRN9; Q9NVX1"	""	""	"0"	"0"	"56.0"	"46.2"	"62.0"	"54.3"	"73.5"	"60.7"	"87.1"	"152.4"	"593.5"	"1431.2"	"2081.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07947"	"Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3"	"6"	"3"	"4"	"3"	"543"	"60.8"	"6.74"	"935.55"	"6.91"	"2"	"2"	"protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi"	"signal transduction activity or receptor binding;kinase activity;other molecular function"	"Pf00017, Pf00018, Pf07714"	"7525"	"ENSG00000176105"	"YES1"	"A6NLB3; D3DUH1; hsa:7525; P07947"	"Thymic stromal lymphopoietin (TSLP) signaling pathway; Interleukin-11 signaling pathway; NRF2-ARE regulation; Gastrin signaling pathway; GDNF signaling"	"FCGR activation; FCGR3A-mediated IL10 synthesis; FCGR3A-mediated phagocytosis; Regulation of signaling by CBL; EPHB-mediated forward signaling; Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants; Regulation of KIT signaling; Signaling by ERBB2; EPH-ephrin mediated repulsion of cells; EPHA-mediated growth cone collapse; Signaling by CSF1 (M-CSF) in myeloid cells; RUNX2 regulates osteoblast differentiation; CD28 co-stimulation; PECAM1 interactions; CTLA4 inhibitory signaling"	"22"	"0"	"147.1"	"154.3"	"133.2"	"119.6"	"135.9"	"142.6"	"177.0"	"242.3"	"421.6"	"819.8"	"1565.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q03001"	"Dystonin OS=Homo sapiens OX=9606 GN=DST PE=1 SV=4"	"0"	"2"	"4"	"1"	"7570"	"860.1"	"5.25"	"1014.98"	"6.90"	"2"	"2"	"cell adhesion;cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"extracellular matrix;plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00307, Pf00435, Pf00681, Pf02187, Pf13499, Pf17902, Pf18373"	"667"	"ENSG00000151914"	"DST"	"B7Z3H1; E7ERU0; hsa:667; O94833; Q03001; Q12825; Q13266; Q13267; Q13775; Q5TBT0; Q5TBT2; Q5TF23; Q5TF24; Q8N1T8; Q8N8J3; Q8WXK8; Q8WXK9; Q96AK9; Q96DQ5; Q96J76; Q96QT5; Q9H555; Q9UGD7; Q9UGD8; Q9UN10"	""	"RND2 GTPase cycle; RHOV GTPase cycle; RHOU GTPase cycle; RND3 GTPase cycle; RND1 GTPase cycle; Type I hemidesmosome assembly"	"6"	"0"	"14.7"	"7.9"	"12.8"	"8.9"	"9.7"	"14.5"	"15.8"	"23.3"	"39.7"	"74.8"	"117.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62306"	"Small nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=SNRPF PE=1 SV=1"	"15"	"1"	"4"	"1"	"86"	"9.7"	"4.67"	"804.28"	"6.90"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01423"	"6636"	"ENSG00000139343"	"SNRPF"	"A2VCR2; B2R498; hsa:6636; P62306; Q15356; Q6IBQ1; Q6P4I0"	"mRNA processing"	"snRNP Assembly; mRNA Splicing - Major Pathway; SARS-CoV-2 modulates host translation machinery; mRNA Splicing - Minor Pathway; RNA Polymerase II Transcription Termination; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"8"	"0"	"18.7"	"25.2"	"28.4"	"21.6"	"19.8"	"21.6"	"24.2"	"36.3"	"57.5"	"109.1"	"179.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P78368"	"Casein kinase I isoform gamma-2 OS=Homo sapiens OX=9606 GN=CSNK1G2 PE=1 SV=1"	"7"	"2"	"3"	"2"	"415"	"47.4"	"9.06"	"253.66"	"6.89"	"1"	"2"	"cell-cell signaling;protein metabolism;other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf12605"	"1455"	"ENSG00000133275"	"CSNK1G2"	"B5BU42; hsa:1455; O00704; P78368; Q8WUB1"	"Hedgehog signaling pathway"	"Sphingolipid de novo biosynthesis; Disassembly of the destruction complex and recruitment of AXIN to the membrane"	"3"	"0"	"32.8"	"38.7"	"49.5"	"35.6"	"46.7"	"45.1"	"55.8"	"74.2"	"208.6"	"475.7"	"654.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NSV4"	"Protein diaphanous homolog 3 OS=Homo sapiens OX=9606 GN=DIAPH3 PE=1 SV=4"	"2"	"2"	"4"	"2"	"1193"	"136.8"	"7.03"	"642.78"	"6.88"	"2"	"2"	"cell organization and biogenesis"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02181, Pf06367, Pf06371"	"81624"	"ENSG00000139734"	"DIAPH3"	"A2A3B8; A2A3B9; A2A3C0; hsa:81624; Q18P99; Q18PA0; Q18PA1; Q2KPB6; Q3ZK23; Q5JTP8; Q5T2S7; Q5XKF6; Q6MZF0; Q6NUP0; Q86VS4; Q8NAV4; Q9NSV4"	"Regulation of actin cytoskeleton"	"RHO GTPases Activate Formins; RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RHOG GTPase cycle; RAC3 GTPase cycle; RHOB GTPase cycle; RHOD GTPase cycle; RHOJ GTPase cycle; RHOF GTPase cycle; RAC2 GTPase cycle"	"14"	"0"	"129.4"	"133.1"	"133.6"	"125.2"	"140.7"	"135.7"	"168.3"	"207.3"	"427.6"	"778.2"	"1006.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6ZW49"	"PAX-interacting protein 1 OS=Homo sapiens OX=9606 GN=PAXIP1 PE=1 SV=2"	"3"	"2"	"4"	"2"	"1069"	"121.3"	"6.70"	"912.40"	"6.87"	"2"	"2"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	""	"Pf00533, Pf12738"	"22976"	"ENSG00000157212"	"PAXIP1"	"hsa:22976; O15404; Q6N099; Q6ZW49; Q6ZWH9; Q7Z315; Q86UN0; Q8N4P9; Q96HP2"	"16p11.2 proximal deletion syndrome; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; Kleefstra syndrome"	"Formation of WDR5-containing histone-modifying complexes; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Nonhomologous End-Joining (NHEJ)"	"6"	"0"	"3.8"	"4.9"	"7.2"	"7.1"	"3.4"	"4.4"	"9.9"	"10.5"	"17.2"	"23.2"	"32.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15050"	"Ribosome biogenesis regulatory protein homolog OS=Homo sapiens OX=9606 GN=RRS1 PE=1 SV=2"	"7"	"1"	"1"	"1"	"365"	"41.2"	"10.70"	""	"6.87"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity"	"Pf04939"	"23212"	"ENSG00000179041"	"RRS1"	"hsa:23212; Q15050; Q9BUX8"	""	""	"0"	"0"	"20.7"	"18.1"	"25.6"	"18.9"	"23.5"	"25.1"	"33.7"	"40.9"	"61.7"	"96.6"	"168.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51649"	"Succinate-semialdehyde dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH5A1 PE=1 SV=2"	"8"	"2"	"3"	"2"	"535"	"57.2"	"8.28"	"383.68"	"6.86"	"1"	"2"	"other metabolic processes;developmental processes"	"mitochondrion"	"other molecular function"	"Pf00171"	"7915"	"ENSG00000112294"	"ALDH5A1"	"B2RD26; G5E949; hsa:7915; P51649; Q546H9; Q8N3W6"	"Fragile X syndrome"	"Degradation of GABA"	"2"	"0"	"17.3"	"15.6"	"20.6"	"16.9"	"16.0"	"15.3"	"25.1"	"46.1"	"87.7"	"187.6"	"347.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46100"	"Transcriptional regulator ATRX OS=Homo sapiens OX=9606 GN=ATRX PE=1 SV=5"	"1"	"2"	"4"	"2"	"2492"	"282.4"	"6.58"	"808.53"	"6.85"	"2"	"2"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"131.3"	"106.5"	"143.6"	"117.1"	"135.5"	"122.7"	"157.2"	"189.4"	"281.5"	"542.0"	"844.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43865"	"S-adenosylhomocysteine hydrolase-like protein 1 OS=Homo sapiens OX=9606 GN=AHCYL1 PE=1 SV=2"	"4"	"3"	"5"	"3"	"530"	"58.9"	"6.89"	"1382.68"	"6.84"	"3"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00670, Pf05221"	"10768"	"ENSG00000168710"	"AHCYL1"	"B4E168; hsa:10768; O43865; Q2TAJ6; Q502W8; Q5VSM0; Q6P171; Q96PK4; Q9UG84"	"Trans-sulfuration, one-carbon metabolism and related pathways"	"Role of phospholipids in phagocytosis; FCERI mediated Ca+2 mobilization; FCGR3A-mediated IL10 synthesis; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Ion homeostasis; Regulation of insulin secretion; VEGFR2 mediated cell proliferation; PLC beta mediated events; DAG and IP3 signaling; CLEC7A (Dectin-1) induces NFAT activation"	"11"	"0"	"233.6"	"193.0"	"244.4"	"223.4"	"241.9"	"258.0"	"291.0"	"325.0"	"414.7"	"815.2"	"1537.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6WKZ4"	"Rab11 family-interacting protein 1 OS=Homo sapiens OX=9606 GN=RAB11FIP1 PE=1 SV=3"	"2"	"3"	"5"	"3"	"1283"	"137.1"	"5.43"	"1320.20"	"6.83"	"3"	"2"	"transport;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00168, Pf09457"	"80223"	"ENSG00000156675"	"RAB11FIP1"	"hsa:80223; J3KNP0; Q307T1; Q6AZK4; Q6WKZ2; Q6WKZ4; Q6WKZ6; Q86YV4; Q8TDL1; Q9H642"	""	""	"0"	"0"	"114.5"	"90.5"	"125.1"	"131.4"	"154.4"	"232.0"	"471.3"	"612.5"	"592.9"	"652.0"	"701.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HAJ7"	"Histone deacetylase complex subunit SAP30L OS=Homo sapiens OX=9606 GN=SAP30L PE=1 SV=1"	"11"	"2"	"4"	"2"	"183"	"20.9"	"9.36"	"718.68"	"6.83"	"2"	"2"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf13866, Pf13867"	"79685"	"ENSG00000164576"	"SAP30L"	"E9PAU7; E9PAY2; hsa:79685; Q9HAJ7"	""	"Potential therapeutics for SARS; HDACs deacetylate histones; NoRC negatively regulates rRNA expression"	"3"	"0"	"93.4"	"75.4"	"109.0"	"77.3"	"110.0"	"67.9"	"114.6"	"185.3"	"381.6"	"850.2"	"1580.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22314"	"Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3"	"4"	"2"	"3"	"2"	"1058"	"117.8"	"5.76"	"415.34"	"6.83"	"1"	"2"	"protein metabolism;other metabolic processes;stress response"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00899, Pf09358, Pf10585, Pf16190, Pf16191"	"7317"	"ENSG00000130985"	"UBA1"	"hsa:7317; P22314; Q5JRR8; Q96E13"	"Proteasome degradation; Parkin-ubiquitin proteasomal system pathway; Parkinson's disease pathway"	"Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Antigen processing: Ubiquitination & Proteasome degradation"	"5"	"0"	"4.6"	"12.1"	"4.4"	"5.7"	"5.3"	"4.8"	"8.8"	"19.1"	"33.2"	"55.5"	"168.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50454"	"Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2"	"9"	"3"	"5"	"3"	"418"	"46.4"	"8.69"	"1187.13"	"6.82"	"3"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"non-structural extracellular;other membranes;ER/Golgi"	"enzyme regulator activity;other molecular function"	"Pf00079"	"871"	"ENSG00000149257"	"SERPINH1"	"B3KVJ3; hsa:871; P29043; P50454; Q5XPB4; Q6NSJ6; Q8IY96; Q9NP88"	"Endochondral ossification; Type I collagen synthesis in the context of osteogenesis imperfecta; Endochondral ossification with skeletal dysplasias; 15q13.3 copy number variation syndrome; 15q11q13 copy number variation"	"Collagen biosynthesis and modifying enzymes"	"6"	"0"	"59.2"	"47.1"	"84.6"	"62.2"	"80.8"	"83.0"	"94.8"	"110.3"	"207.3"	"322.1"	"418.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TAD8"	"Smad nuclear-interacting protein 1 OS=Homo sapiens OX=9606 GN=SNIP1 PE=1 SV=1"	"5"	"1"	"2"	"1"	"396"	"45.8"	"9.99"	"749.07"	"6.80"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity"	"Pf00498"	"79753"	"ENSG00000163877"	"SNIP1"	"hsa:79753; Q8TAD8; Q96SP9; Q9H9T7"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"28.2"	"26.8"	"28.9"	"25.0"	"27.3"	"29.1"	"31.3"	"37.8"	"93.3"	"347.9"	"532.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TDP1"	"Ribonuclease H2 subunit C OS=Homo sapiens OX=9606 GN=RNASEH2C PE=1 SV=1"	"13"	"2"	"3"	"2"	"164"	"17.8"	"5.03"	"358.52"	"6.80"	"1"	"2"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response"	"nucleus;other cell component"	""	"Pf08615"	"84153"	"ENSG00000172922"	"RNASEH2C"	"hsa:84153; Q8TDP1; Q9H7F5"	""	""	"0"	"0"	"58.6"	"67.4"	"82.2"	"64.5"	"69.0"	"68.6"	"88.7"	"143.0"	"685.3"	"1247.5"	"1627.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NP97"	"Dynein light chain roadblock-type 1 OS=Homo sapiens OX=9606 GN=DYNLRB1 PE=1 SV=3"	"29"	"2"	"4"	"2"	"96"	"10.9"	"7.25"	"993.87"	"6.79"	"2"	"2"	"other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03259"	"83658"	"ENSG00000125971"	"DYNLRB1"	"B1AKR5; hsa:83658; Q5TC72; Q96IV3; Q9NP97; Q9NQM2"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein; 3q29 copy number variation syndrome"	"Intraflagellar transport"	"4"	"0"	"77.8"	"66.3"	"91.8"	"75.8"	"89.7"	"86.8"	"112.4"	"122.1"	"215.3"	"352.0"	"520.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q93074"	"Mediator of RNA polymerase II transcription subunit 12 OS=Homo sapiens OX=9606 GN=MED12 PE=1 SV=4"	"1"	"2"	"4"	"2"	"2177"	"242.9"	"7.05"	"728.21"	"6.79"	"2"	"2"	"cell-cell signaling;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09497, Pf12144, Pf12145"	"9968"	"ENSG00000184634"	"MED12"	"hsa:9968; O15410; O75557; Q93074; Q9UHV6; Q9UND7"	""	"PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; Generic Transcription Pathway"	"3"	"0"	"20.0"	"16.2"	"24.7"	"21.7"	"23.8"	"24.7"	"26.0"	"38.6"	"59.5"	"139.8"	"192.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P36551"	"Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3"	"4"	"1"	"2"	"1"	"454"	"50.1"	"8.25"	"742.35"	"6.76"	"1"	"1"	"other metabolic processes;other biological processes"	"other membranes;cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf01218"	"1371"	"ENSG00000080819"	"CPOX"	"A8K275; B4DSD5; hsa:1371; P36551; Q14060; Q53F08; Q8IZ45; Q96AF3"	"Hemesynthesis defects and porphyrias; Heme biosynthesis"	"Heme biosynthesis"	"3"	"0"	"8.2"	"11.9"	"13.5"	"12.7"	"11.2"	"9.1"	"9.0"	"17.3"	"49.3"	"257.9"	"945.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51116"	"Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2"	"3"	"2"	"4"	"1"	"673"	"74.2"	"6.23"	"811.13"	"6.74"	"2"	"2"	"developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf05641, Pf12235, Pf16096, Pf17904, Pf18336"	"9513"	"ENSG00000129245"	"FXR2"	"B2R9M2; D3DTQ1; hsa:9513; P51116; Q86V09; Q8WUM2"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"119.4"	"65.9"	"112.8"	"116.6"	"124.9"	"127.4"	"141.6"	"149.7"	"239.3"	"367.1"	"562.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96C57"	"Protein CUSTOS OS=Homo sapiens OX=9606 GN=CUSTOS PE=1 SV=2"	"11"	"2"	"3"	"2"	"262"	"28.2"	"9.42"	"981.85"	"6.74"	"2"	"1"	"cell-cell signaling;signal transduction;other biological processes"	"nucleus"	""	""	"64897"	"ENSG00000157895"	"CUSTOS"	"hsa:64897; Q53HF0; Q96C57; Q9H9Z7"	""	""	"0"	"0"	"93.4"	"84.6"	"98.4"	"100.3"	"98.1"	"99.1"	"114.0"	"146.5"	"259.3"	"368.2"	"386.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49642"	"DNA primase small subunit OS=Homo sapiens OX=9606 GN=PRIM1 PE=1 SV=1"	"5"	"2"	"4"	"2"	"420"	"49.9"	"8.21"	"714.67"	"6.74"	"2"	"2"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf01896"	"5557"	"ENSG00000198056"	"PRIM1"	"hsa:5557; P49642"	"Retinoblastoma gene in cancer; Pyrimidine metabolism; G1 to S cell cycle control; DNA replication"	"Activation of the pre-replicative complex; Removal of the Flap Intermediate; Defective pyroptosis; Inhibition of replication initiation of damaged DNA by RB1/E2F1; Polymerase switching on the C-strand of the telomere; Telomere C-strand synthesis initiation; DNA replication initiation; Polymerase switching"	"13"	"0"	"59.9"	"55.1"	"62.3"	"61.1"	"66.3"	"60.6"	"81.4"	"102.5"	"239.3"	"647.2"	"771.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P42566"	"Epidermal growth factor receptor substrate 15 OS=Homo sapiens OX=9606 GN=EPS15 PE=1 SV=2"	"3"	"2"	"4"	"2"	"896"	"98.6"	"4.64"	"905.00"	"6.72"	"2"	"2"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	""	"2060"	"ENSG00000085832"	"EPS15"	"B2R8J7; D3DPJ2; hsa:2060; P42566; Q5SRH4"	"VEGFA-VEGFR2 signaling; Ebola virus infection in host; EGF/EGFR signaling pathway"	"Cargo recognition for clathrin-mediated endocytosis; EGFR downregulation; Negative regulation of MET activity; InlB-mediated entry of Listeria monocytogenes into host cell"	"8"	"0"	"31.3"	"25.1"	"33.5"	"30.7"	"30.1"	"32.1"	"36.6"	"44.5"	"60.0"	"82.3"	"96.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5K6"	"CD2-associated protein OS=Homo sapiens OX=9606 GN=CD2AP PE=1 SV=1"	"4"	"2"	"4"	"2"	"639"	"71.4"	"6.40"	"608.53"	"6.72"	"2"	"2"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00018, Pf14604"	"23607"	"ENSG00000198087"	"CD2AP"	"A6NL34; hsa:23607; Q5VYA3; Q9UG97; Q9Y5K6"	"Primary focal segmental glomerulosclerosis (FSGS); Nephrotic syndrome; Genes controlling nephrogenesis; GDNF signaling"	"Nephrin family interactions"	"5"	"0"	"39.5"	"40.1"	"38.6"	"37.4"	"51.0"	"38.6"	"49.7"	"71.5"	"163.3"	"374.6"	"500.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94979"	"Protein transport protein Sec31A OS=Homo sapiens OX=9606 GN=SEC31A PE=1 SV=3"	"2"	"2"	"4"	"2"	"1220"	"132.9"	"6.89"	"714.57"	"6.71"	"2"	"2"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf12931"	"22872"	"ENSG00000138674"	"SEC31A"	"B4DIW6; B7ZKZ7; B7ZL00; H7C2W3; hsa:22872; O94979; Q17RR5; Q5H9P6; Q5XG74; Q659G7; Q6ZU90; Q7LCX9; Q86TJ0; Q8IZH4; Q9P048; Q9P0A6; Q9UM05; Q9UM06"	"Sterol regulatory element-binding proteins (SREBP) signaling"	"MHC class II antigen presentation; Signaling by ALK fusions and activated point mutants; COPII-mediated vesicle transport; XBP1(S) activates chaperone genes; Antigen Presentation: Folding, assembly and peptide loading of class I MHC"	"6"	"0"	"64.5"	"69.9"	"75.6"	"56.9"	"76.4"	"67.5"	"96.1"	"114.7"	"335.7"	"851.1"	"1180.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P36959"	"GMP reductase 1 OS=Homo sapiens OX=9606 GN=GMPR PE=1 SV=1"	"9"	"2"	"2"	"1"	"345"	"37.4"	"7.06"	""	"6.70"	""	"2"	"other metabolic processes;stress response"	"cytosol;other cell component"	"other molecular function"	"Pf00478"	"2766"	"ENSG00000137198"	"GMPR"	"hsa:2766; P36959; Q96HQ6"	""	"Purine salvage"	"1"	"0"	"0.0"	"0.0"	"3.1"	"2.5"	"0.0"	"0.0"	"4.2"	"20.6"	"40.0"	"76.7"	"157.0"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UQR0"	"Sex comb on midleg-like protein 2 OS=Homo sapiens OX=9606 GN=SCML2 PE=1 SV=1"	"4"	"2"	"4"	"2"	"700"	"77.2"	"8.54"	"596.14"	"6.69"	"2"	"2"	"other biological processes"	"nucleus"	""	"Pf00536, Pf02820, Pf12140, Pf17208"	"10389"	"ENSG00000102098"	"SCML2"	"hsa:10389; Q5JXE6; Q86U98; Q8IWD0; Q8NDP2; Q9UGC5; Q9UQR0"	""	""	"0"	"0"	"96.0"	"73.0"	"97.3"	"101.1"	"98.4"	"97.4"	"117.6"	"103.3"	"173.4"	"297.6"	"412.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86WW8"	"Cytochrome c oxidase assembly factor 5 OS=Homo sapiens OX=9606 GN=COA5 PE=1 SV=1"	"30"	"2"	"4"	"2"	"74"	"8.4"	"8.68"	"842.07"	"6.69"	"2"	"2"	"cell organization and biogenesis"	"mitochondrion"	""	"Pf10203"	"493753"	"ENSG00000183513"	"COA5"	"hsa:493753; Q86WW8"	""	""	"0"	"0"	"460.7"	"458.8"	"309.2"	"277.1"	"401.9"	"34.0"	"417.7"	"1254.1"	"1481.8"	"1664.5"	"1476.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UGM6"	"Tryptophan--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=WARS2 PE=1 SV=1"	"6"	"2"	"4"	"2"	"360"	"40.1"	"9.28"	"682.00"	"6.69"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf00579"	"10352"	"ENSG00000116874"	"WARS2"	"B1ALR1; B2R9D4; hsa:10352; Q53FT4; Q5VUD2; Q86TQ0; Q9UGM6"	""	"Mitochondrial tRNA aminoacylation"	"1"	"0"	"104.5"	"95.2"	"115.4"	"98.9"	"113.1"	"115.5"	"123.2"	"136.0"	"315.7"	"776.6"	"879.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EY7"	"Pentatricopeptide repeat domain-containing protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=PTCD3 PE=1 SV=3"	"4"	"2"	"4"	"2"	"689"	"78.5"	"6.42"	"721.60"	"6.64"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;translational apparatus;nucleus"	"translation activity;nucleic acid binding activity"	"Pf13041, Pf13812"	"55037"	"ENSG00000132300"	"PTCD3"	"A6NHD2; D6W5M1; hsa:55037; Q597H0; Q658Y9; Q96EY7; Q9BUZ8; Q9NWL0"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"22.5"	"15.2"	"25.1"	"23.9"	"28.3"	"30.4"	"30.9"	"33.9"	"70.1"	"123.6"	"157.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13596"	"Sorting nexin-1 OS=Homo sapiens OX=9606 GN=SNX1 PE=1 SV=3"	"4"	"2"	"2"	"1"	"522"	"59.0"	"5.15"	""	"6.64"	""	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00787, Pf03700, Pf09325"	"6642"	"ENSG00000028528"	"SNX1"	"A6NM19; A8K6T7; H0Y2M5; hsa:6642; O60750; O60751; Q13596; Q6ZRJ8"	""	""	"0"	"0"	"5.7"	"2.7"	"3.7"	"3.8"	"3.6"	"4.6"	"4.6"	"7.5"	"28.6"	"99.9"	"293.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62714"	"Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform OS=Homo sapiens OX=9606 GN=PPP2CB PE=1 SV=1"	"10"	"2"	"3"	"2"	"309"	"35.6"	"5.43"	"362.04"	"6.62"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00149"	"5516"	"ENSG00000104695"	"PPP2CB"	"D3DSV4; hsa:5516; P11082; P62714; Q6FHK5"	"Serotonin transporter activity; Dopamine metabolism; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Wnt signaling pathway and pluripotency; Exercise-induced circadian regulation; PI3K-Akt signaling pathway; 16p11.2 proximal deletion syndrome; Glycogen synthesis and degradation; Cohesin complex - Cornelia de Lange syndrome; Monoamine transport"	"Regulation of TP53 Degradation; Cyclin D associated events in G1; Cyclin A/B1/B2 associated events during G2/M transition; RAF activation; Negative regulation of MAPK pathway; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Disassembly of the destruction complex and recruitment of AXIN to the membrane; Beta-catenin phosphorylation cascade; Signaling by GSK3beta mutants; CTNNB1 S33 mutants aren't phosphorylated; CTNNB1 S37 mutants aren't phosphorylated; CTNNB1 S45 mutants aren't phosphorylated; CTNNB1 T41 mutants aren't phosphorylated; APC truncation mutants have impaired AXIN binding; AXIN missense mutants destabilize the destruction complex; Truncations of AMER1 destabilize the destruction complex; Spry regulation of FGF signaling; MASTL Facilitates Mitotic Progression; Regulation of glycolysis by fructose 2,6-bisphosphate metabolism; Platelet sensitization by LDL; CTLA4 inhibitory signaling; Inhibition of replication initiation of damaged DNA by RB1/E2F1; DARPP-32 events; PP2A-mediated dephosphorylation of key metabolic factors; ERKs are inactivated"	"44"	"0"	"73.7"	"65.6"	"65.4"	"74.1"	"73.9"	"71.1"	"82.6"	"129.0"	"170.7"	"267.2"	"349.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P2K5"	"Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3"	"4"	"2"	"4"	"2"	"600"	"64.1"	"8.75"	"607.71"	"6.60"	"2"	"2"	"developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076"	"50804"	"ENSG00000104177"	"MYEF2"	"A7MCZ9; C9J921; C9K0J4; hsa:50804; Q6NUM5; Q7L388; Q7Z4B7; Q9H922; Q9NUQ1; Q9P2K5"	"Physiological and pathological hypertrophy of the heart; MicroRNAs in cardiomyocyte hypertrophy; Transcription factors regulate miRNAs related to cardiac hypertrophy; Mitochondrial gene expression"	""	"4"	"0"	"37.7"	"40.5"	"45.5"	"43.0"	"43.3"	"36.1"	"49.7"	"72.8"	"107.5"	"259.1"	"404.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43324"	"Eukaryotic translation elongation factor 1 epsilon-1 OS=Homo sapiens OX=9606 GN=EEF1E1 PE=1 SV=1"	"12"	"2"	"4"	"2"	"174"	"19.8"	"8.54"	"711.84"	"6.60"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf00043"	"9521"	"ENSG00000124802"	"EEF1E1"	"C9JLK5; hsa:9521; O43324; Q5THS2"	""	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"2"	"0"	"70.3"	"63.3"	"74.6"	"60.5"	"58.6"	"75.9"	"91.7"	"132.1"	"273.3"	"605.4"	"852.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35249"	"Replication factor C subunit 4 OS=Homo sapiens OX=9606 GN=RFC4 PE=1 SV=2"	"13"	"3"	"4"	"3"	"363"	"39.7"	"8.02"	"725.60"	"6.60"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00004, Pf08542"	"5984"	"ENSG00000163918"	"RFC4"	"B4DM41; D3DNV2; hsa:5984; P35249; Q6FHX7"	"Gastric cancer network 2; Retinoblastoma gene in cancer; DNA replication; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"Regulation of TP53 Activity through Phosphorylation; Activation of ATR in response to replication stress; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Polymerase switching on the C-strand of the telomere; Polymerase switching; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER"	"28"	"0"	"360.2"	"341.7"	"353.1"	"329.3"	"369.2"	"363.8"	"431.8"	"479.3"	"892.6"	"1432.1"	"1989.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BYI3"	"Hyccin OS=Homo sapiens OX=9606 GN=FAM126A PE=1 SV=2"	"4"	"2"	"4"	"2"	"521"	"57.6"	"8.16"	"705.08"	"6.59"	"2"	"2"	"other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf09790"	"84668"	"ENSG00000122591"	"HYCC1"	"A0A024RA06; A4D145; B8ZZJ1; hsa:84668; Q6N010; Q75MR4; Q7LDZ4; Q96MX1; Q96NQ6; Q9BYI3"	""	""	"0"	"0"	"61.4"	"53.3"	"76.8"	"56.9"	"74.7"	"73.3"	"73.3"	"127.6"	"314.6"	"431.8"	"552.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y388"	"RNA-binding motif protein, X-linked 2 OS=Homo sapiens OX=9606 GN=RBMX2 PE=1 SV=2"	"9"	"2"	"4"	"2"	"322"	"37.3"	"9.83"	"924.53"	"6.58"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"other membranes;ER/Golgi;nucleus"	""	"Pf00076"	"51634"	"ENSG00000134597"	"RBMX2"	"A8K9Z0; hsa:51634; Q5JY82; Q9Y388; Q9Y3I8"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"103.6"	"81.7"	"88.7"	"87.5"	"97.3"	"105.1"	"113.3"	"128.9"	"197.7"	"357.9"	"470.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95248"	"Myotubularin-related protein 5 OS=Homo sapiens OX=9606 GN=SBF1 PE=1 SV=4"	"1"	"2"	"4"	"2"	"1868"	"208.3"	"6.90"	"613.09"	"6.58"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf02141, Pf02893, Pf03456, Pf06602, Pf12335"	"6305"	"ENSG00000100241"	"SBF1"	"A0A024R4Z9; A6PVG9; G5E933; hsa:6305; O60228; O95248; Q5JXD8; Q5PPM2; Q96GR9; Q9UGB8"	""	"RAB GEFs exchange GTP for GDP on RABs; Synthesis of PIPs at the ER membrane"	"2"	"0"	"36.7"	"33.8"	"52.6"	"45.8"	"45.9"	"58.1"	"99.8"	"226.6"	"381.4"	"417.4"	"420.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75334"	"Liprin-alpha-2 OS=Homo sapiens OX=9606 GN=PPFIA2 PE=1 SV=2"	"4"	"3"	"4"	"1"	"1257"	"143.2"	"6.11"	"958.45"	"6.57"	"2"	"2"	"cell adhesion;cell organization and biogenesis;transport;other biological processes"	"cytosol;other cell component"	""	"Pf00536, Pf07647"	"8499"	"ENSG00000139220"	"PPFIA2"	"B3KVT5; B3KXA0; B7Z2A6; B7Z3U9; B7Z663; B7ZKZ5; E7ERB8; E7ETG6; F8VP68; hsa:8499; O75334; Q2M3G8"	""	"Glutamate Neurotransmitter Release Cycle; Serotonin Neurotransmitter Release Cycle; Norepinephrine Neurotransmitter Release Cycle; Dopamine Neurotransmitter Release Cycle; Acetylcholine Neurotransmitter Release Cycle; Receptor-type tyrosine-protein phosphatases"	"6"	"0"	"11.1"	"3.4"	"17.1"	"12.2"	"16.1"	"12.0"	"11.1"	"12.3"	"61.7"	"147.4"	"277.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51858"	"Hepatoma-derived growth factor OS=Homo sapiens OX=9606 GN=HDGF PE=1 SV=1"	"10"	"2"	"3"	"2"	"240"	"26.8"	"4.73"	"477.53"	"6.56"	"1"	"2"	"cell organization and biogenesis;signal transduction;other biological processes"	"nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00855"	"3068"	"ENSG00000143321"	"HDGF"	"B3KU21; D3DVC9; hsa:3068; P51858; Q5SZ07; Q5SZ08; Q5SZ09"	"IL-18 signaling pathway"	"XBP1(S) activates chaperone genes"	"2"	"0"	"94.2"	"73.0"	"107.0"	"106.9"	"89.6"	"85.9"	"104.4"	"133.1"	"220.5"	"466.8"	"1578.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P0V9"	"Septin-10 OS=Homo sapiens OX=9606 GN=SEPTIN10 PE=1 SV=2"	"7"	"2"	"3"	"1"	"454"	"52.6"	"6.80"	"382.60"	"6.55"	"1"	"2"	"cell cycle OR cell proliferation"	"cytoskeleton;other cell component"	"other molecular function"	"Pf00735"	"151011"	"ENSG00000186522"	"SEPTIN10"	"B3KRQ9; hsa:151011; Q86VP5; Q9HAH6; Q9P0V9"	""	""	"0"	"0"	"9.7"	"7.9"	"12.7"	"7.7"	"9.3"	"9.0"	"10.9"	"29.1"	"112.9"	"189.0"	"235.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HCD5"	"Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2"	"4"	"2"	"3"	"2"	"579"	"65.5"	"9.60"	"505.32"	"6.54"	"1"	"2"	"signal transduction;other biological processes"	"cytoskeleton;nucleus"	"other molecular function"	""	"57727"	"ENSG00000124160"	"NCOA5"	"B2RTV9; E1P5R0; hsa:57727; Q6HA99; Q9H1F2; Q9H2T2; Q9H4Y9; Q9HCD5"	""	""	"0"	"0"	"151.4"	"181.0"	"134.5"	"112.5"	"130.1"	"126.0"	"160.8"	"306.9"	"425.5"	"670.7"	"948.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60684"	"Importin subunit alpha-7 OS=Homo sapiens OX=9606 GN=KPNA6 PE=1 SV=1"	"4"	"2"	"4"	"2"	"536"	"60.0"	"4.98"	"731.26"	"6.54"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00514, Pf01749, Pf16186"	"23633"	"ENSG00000025800"	"KPNA6"	"B2RDC7; D3DPP5; hsa:23633; O60684; Q5VVU3"	""	"Assembly of the ORC complex at the origin of replication"	"1"	"0"	"38.6"	"36.3"	"38.9"	"37.7"	"42.6"	"48.9"	"63.0"	"89.9"	"166.0"	"366.7"	"592.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99618"	"Cell division cycle-associated protein 3 OS=Homo sapiens OX=9606 GN=CDCA3 PE=1 SV=1"	"10"	"1"	"1"	"1"	"268"	"29.0"	"6.43"	""	"6.53"	""	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	""	""	"83461"	"ENSG00000111665"	"CDCA3"	"A8K5V6; D3DUS6; hsa:83461; Q99618"	""	""	"0"	"0"	"10.6"	"12.7"	"18.2"	"14.2"	"21.1"	"19.0"	"21.9"	"18.2"	"43.7"	"85.3"	"128.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60551"	"Glycylpeptide N-tetradecanoyltransferase 2 OS=Homo sapiens OX=9606 GN=NMT2 PE=1 SV=1"	"8"	"3"	"5"	"1"	"498"	"56.9"	"7.58"	"1137.97"	"6.53"	"3"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf01233, Pf02799"	"9397"	"ENSG00000152465"	"NMT2"	"B0YJ49; hsa:9397; O60551; Q53Y38; Q5VUC8; Q9BRB4"	""	"Membrane binding and targetting of GAG proteins; Inactivation, recovery and regulation of the phototransduction cascade"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BYD1"	"39S ribosomal protein L13, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL13 PE=1 SV=1"	"8"	"1"	"2"	"1"	"178"	"20.7"	"9.16"	"627.52"	"6.53"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00572"	"28998"	"ENSG00000172172"	"MRPL13"	"B2R4R8; hsa:28998; Q9BYD1; Q9UI04"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"40.8"	"41.3"	"43.5"	"36.1"	"41.3"	"39.8"	"48.6"	"61.3"	"86.5"	"152.6"	"227.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92552"	"28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3"	"9"	"3"	"5"	"3"	"414"	"47.6"	"6.18"	"1103.53"	"6.52"	"3"	"2"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf10037"	"23107"	"ENSG00000113048"	"MRPS27"	"B4DRT2; hsa:23107; Q6P1S1; Q92552"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"101.2"	"103.0"	"110.2"	"95.9"	"117.5"	"120.6"	"140.1"	"206.6"	"398.2"	"686.7"	"1010.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51812"	"Ribosomal protein S6 kinase alpha-3 OS=Homo sapiens OX=9606 GN=RPS6KA3 PE=1 SV=1"	"3"	"2"	"4"	"1"	"740"	"83.7"	"6.89"	"805.99"	"6.52"	"2"	"2"	"cell-cell signaling;cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069, Pf00433"	"6197"	"ENSG00000177189"	"RPS6KA3"	"B2R9V4; hsa:6197; P51812; Q4VAP3; Q59H26; Q5JPK8; Q7Z3Z7"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; Kit receptor signaling pathway; MAPK signaling pathway; Angiopoietin-like protein 8 regulatory pathway; Thermogenesis; EGF/EGFR signaling pathway; Cytoplasmic ribosomal proteins; Insulin signaling; Host-pathogen interaction of human coronaviruses - MAPK signaling; Pleural mesothelioma; A network map of Macrophage-stimulating protein (MSP) signaling"	"Recycling pathway of L1; Senescence-Associated Secretory Phenotype (SASP); RSK activation; ERK/MAPK targets; CREB phosphorylation; Gastrin-CREB signalling pathway via PKC and MAPK"	"18"	"0"	"14.6"	"11.8"	"14.5"	"10.9"	"13.5"	"10.3"	"18.8"	"22.7"	"52.1"	"91.4"	"107.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IX18"	"Probable ATP-dependent RNA helicase DHX40 OS=Homo sapiens OX=9606 GN=DHX40 PE=1 SV=2"	"4"	"3"	"5"	"3"	"779"	"88.5"	"8.65"	"1135.32"	"6.52"	"3"	"2"	""	""	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"79665"	"ENSG00000108406"	"DHX40"	"B3KTJ5; C9JR60; hsa:79665; Q5JPH4; Q8IX18; Q8TC86; Q8WY53; Q9BXM1; Q9H6M9"	""	""	"0"	"0"	"24.3"	"26.5"	"27.5"	"20.3"	"24.1"	"28.5"	"39.6"	"50.2"	"324.6"	"535.1"	"699.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60318"	"Germinal-center associated nuclear protein OS=Homo sapiens OX=9606 GN=MCM3AP PE=1 SV=2"	"2"	"3"	"5"	"3"	"1980"	"218.3"	"6.39"	"1128.30"	"6.48"	"3"	"2"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03399, Pf16766, Pf16768, Pf16769"	"8888"	"ENSG00000160294"	"MCM3AP"	"C9JL56; hsa:8888; O60318; Q2M3C1; Q6PJP6; Q9BSY5; Q9UMT4"	""	""	"0"	"0"	"38.4"	"41.4"	"41.2"	"38.8"	"38.4"	"35.0"	"52.9"	"61.5"	"146.0"	"257.5"	"363.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15061"	"WD repeat-containing protein 43 OS=Homo sapiens OX=9606 GN=WDR43 PE=1 SV=3"	"6"	"3"	"5"	"3"	"677"	"74.8"	"5.57"	"1323.82"	"6.48"	"3"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00400, Pf04003"	"23160"	"ENSG00000163811"	"WDR43"	"hsa:23160; Q15061; Q15395; Q92577"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"204.8"	"197.5"	"233.2"	"183.0"	"214.7"	"195.5"	"256.5"	"375.4"	"761.9"	"1132.9"	"1371.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NVR2"	"Integrator complex subunit 10 OS=Homo sapiens OX=9606 GN=INTS10 PE=1 SV=2"	"5"	"3"	"5"	"3"	"710"	"82.2"	"7.44"	"966.25"	"6.47"	"3"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	""	"55174"	"ENSG00000104613"	"INTS10"	"hsa:55174; Q6IA93; Q7L538; Q7L8C8; Q9H3W8; Q9NVR2"	"1p36 copy number variation syndrome"	"RNA polymerase II transcribes snRNA genes"	"2"	"0"	"111.7"	"107.7"	"137.3"	"118.8"	"130.5"	"110.2"	"151.7"	"197.1"	"351.1"	"838.5"	"1277.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14155"	"Rho guanine nucleotide exchange factor 7 OS=Homo sapiens OX=9606 GN=ARHGEF7 PE=1 SV=2"	"2"	"1"	"2"	"1"	"803"	"90.0"	"7.09"	"643.26"	"6.43"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00169, Pf00307, Pf00621, Pf07653, Pf16614, Pf16615"	"8874"	"ENSG00000102606"	"ARHGEF7"	"B1ALK6; B1ALK8; hsa:8874; Q14155; Q3LIA4; Q5W9H0; Q6P9G3; Q6PII2; Q86W63; Q8N3M1"	"Integrin-mediated cell adhesion; CAMKK2 pathway; Regulation of actin cytoskeleton"	"RHOV GTPase cycle; RHOU GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; NRAGE signals death through JNK; G alpha (12/13) signalling events; RHOJ GTPase cycle; RHOQ GTPase cycle; Ephrin signaling; EGFR downregulation"	"14"	"0"	"50.0"	"66.6"	"48.5"	"38.1"	"54.7"	"43.2"	"57.0"	"73.0"	"194.0"	"401.2"	"527.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25786"	"Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1"	"8"	"2"	"4"	"2"	"263"	"29.5"	"6.61"	"768.00"	"6.41"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00227, Pf10584"	"5682"	"ENSG00000129084"	"PSMA1"	"A8K400; hsa:5682; P25786; Q53YE8; Q9BRV9"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"MAPK6/MAPK4 signaling; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"62"	"0"	"215.7"	"151.7"	"228.7"	"225.1"	"259.2"	"240.6"	"242.1"	"271.0"	"380.5"	"654.8"	"1632.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BU76"	"Multiple myeloma tumor-associated protein 2 OS=Homo sapiens OX=9606 GN=MMTAG2 PE=1 SV=1"	"6"	"1"	"2"	"1"	"263"	"29.4"	"10.02"	"592.35"	"6.37"	"1"	"1"	""	"non-structural extracellular;other cell component"	""	"Pf10159"	"79169"	"ENSG00000143793"	"MMTAG2"	"hsa:79169; Q6P5Y0; Q6ZTZ6; Q6ZWA6; Q8IZH3; Q9BU76"	""	"Neutrophil degranulation"	"1"	"0"	"31.8"	"30.8"	"42.0"	"31.6"	"36.7"	"35.5"	"37.7"	"55.3"	"100.3"	"166.3"	"241.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TEM1"	"Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3"	"1"	"2"	"4"	"2"	"1887"	"205.0"	"6.81"	"651.42"	"6.35"	"2"	"2"	"transport"	"other membranes;ER/Golgi;nucleus"	""	"Pf02368"	"23225"	"ENSG00000132182"	"NUP210"	"A6NN56; hsa:23225; O94980; Q6NXG6; Q8NBJ1; Q8TEM1; Q9H6C8; Q9UFP3"	""	"SUMOylation of DNA damage response and repair proteins; Vpr-mediated nuclear import of PICs; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Regulation of HSF1-mediated heat shock response; SUMOylation of chromatin organization proteins; HCMV Late Events; SUMOylation of RNA binding proteins; HCMV Early Events; Transcriptional regulation by small RNAs; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; snRNP Assembly; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; SUMOylation of SUMOylation proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus"	"28"	"0"	"34.9"	"28.9"	"38.7"	"35.2"	"39.1"	"35.1"	"46.3"	"64.6"	"91.3"	"314.0"	"591.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q53H47"	"Histone-lysine N-methyltransferase SETMAR OS=Homo sapiens OX=9606 GN=SETMAR PE=1 SV=2"	"5"	"2"	"3"	"2"	"684"	"78.0"	"7.14"	"351.98"	"6.33"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00856, Pf01359, Pf05033, Pf17906"	"6419"	"ENSG00000170364"	"SETMAR"	"B4DY74; E7EN68; hsa:6419; Q13579; Q1G668; Q53H47; Q96F41"	"Histone modifications"	""	"1"	"0"	"3.4"	"0.0"	"3.3"	"2.6"	"2.9"	"0.0"	"4.7"	"1.9"	"18.1"	"41.2"	"57.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q06265"	"Exosome complex component RRP45 OS=Homo sapiens OX=9606 GN=EXOSC9 PE=1 SV=3"	"2"	"1"	"3"	"1"	"439"	"48.9"	"5.29"	"301.69"	"6.33"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01138, Pf03725"	"5393"	"ENSG00000123737"	"EXOSC9"	"hsa:5393; Q06265; Q12883; Q4W5P5; Q86Y41; Q86Y48"	"Ciliary landscape"	"Major pathway of rRNA processing in the nucleolus and cytosol; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	"7"	"0"	"40.8"	"34.1"	"54.1"	"43.7"	"49.9"	"54.5"	"68.2"	"75.4"	"167.7"	"441.7"	"829.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y6X4"	"Soluble lamin-associated protein of 75 kDa OS=Homo sapiens OX=9606 GN=FAM169A PE=1 SV=2"	"2"	"1"	"2"	"1"	"670"	"74.9"	"4.60"	"607.13"	"6.33"	"1"	"1"	""	"other membranes;nucleus"	""	""	"26049"	"ENSG00000198780"	"FAM169A"	"A8K1T9; hsa:26049; Q6MZT0; Q9H989; Q9Y6X4"	""	"RHOF GTPase cycle"	"1"	"0"	"48.4"	"36.6"	"50.8"	"40.6"	"50.5"	"51.2"	"53.0"	"59.1"	"80.1"	"187.2"	"372.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43815"	"Striatin OS=Homo sapiens OX=9606 GN=STRN PE=1 SV=4"	"3"	"2"	"4"	"2"	"780"	"86.1"	"5.27"	"622.35"	"6.32"	"2"	"2"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00400, Pf08232"	"6801"	"ENSG00000115808"	"STRN"	"hsa:6801; O43815; Q3KP65; Q53TQ8; Q9NP38"	""	"PIP3 activates AKT signaling; Extra-nuclear estrogen signaling; ALK mutants bind TKIs; Signaling by ALK fusions and activated point mutants; Constitutive Signaling by Aberrant PI3K in Cancer; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Signaling by cytosolic PDGFRA and PDGFRB fusion proteins"	"7"	"0"	"121.8"	"76.8"	"135.0"	"120.5"	"115.6"	"119.8"	"141.1"	"155.6"	"250.1"	"491.0"	"663.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01780"	"Exosome component 10 OS=Homo sapiens OX=9606 GN=EXOSC10 PE=1 SV=2"	"3"	"2"	"3"	"2"	"885"	"100.8"	"8.46"	"340.00"	"6.32"	"1"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00570, Pf01612, Pf08066"	"5394"	"ENSG00000171824"	"EXOSC10"	"B1AKQ0; B1AKQ1; hsa:5394; Q01780; Q15158"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"179.1"	"123.1"	"182.8"	"190.9"	"156.3"	"154.0"	"193.5"	"287.7"	"352.8"	"467.5"	"745.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43813"	"Glutathione S-transferase LANCL1 OS=Homo sapiens OX=9606 GN=LANCL1 PE=1 SV=1"	"6"	"2"	"4"	"2"	"399"	"45.3"	"7.75"	"651.50"	"6.32"	"2"	"2"	"other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf05147"	"10314"	"ENSG00000115365"	"LANCL1"	"hsa:10314; O43813"	""	""	"0"	"0"	"33.1"	"56.2"	"42.8"	"32.7"	"39.2"	"50.7"	"57.5"	"71.4"	"136.8"	"275.4"	"432.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15545"	"Transcription initiation factor TFIID subunit 7 OS=Homo sapiens OX=9606 GN=TAF7 PE=1 SV=1"	"7"	"2"	"4"	"2"	"349"	"40.2"	"5.20"	"785.02"	"6.32"	"2"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04658"	"6879"	"ENSG00000178913"	"TAF7"	"B2RBV9; hsa:6879; Q13036; Q15545"	"Eukaryotic transcription initiation"	"RNA Polymerase II Pre-transcription Events; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Regulation of TP53 Activity through Phosphorylation"	"10"	"0"	"67.7"	"67.7"	"80.4"	"65.0"	"70.6"	"78.0"	"122.1"	"120.4"	"186.3"	"259.0"	"318.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q02750"	"Dual specificity mitogen-activated protein kinase kinase 1 OS=Homo sapiens OX=9606 GN=MAP2K1 PE=1 SV=2"	"5"	"2"	"2"	"2"	"393"	"43.4"	"6.62"	""	"6.29"	""	"2"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069"	"5604"	"ENSG00000169032"	"MAP2K1"	"hsa:5604; Q02750"	"IL-5 signaling pathway; Osteopontin signaling; MicroRNAs in cardiomyocyte hypertrophy; Integrin-mediated cell adhesion; IL-1 signaling pathway; Thyroxine (thyroid hormone) production; RANKL/RANK signaling pathway; Thyroid stimulating hormone (TSH) signaling pathway; Leptin signaling pathway; Prolactin signaling pathway; IL-7 signaling pathway; Alzheimer's disease and miRNA effects; Endothelin pathways; IL-9 signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; Glioblastoma signaling pathways; Androgen receptor network in prostate cancer; B cell receptor signaling pathway; AGE/RAGE pathway; Interleukin-11 signaling pathway; Corticotropin-releasing hormone signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Aryl hydrocarbon receptor pathway; Common pathways underlying drug addiction; Interleukin-1 (IL-1) structural pathway; Cardiac hypertrophic response; Bladder cancer; IL-3 signaling pathway; Kit receptor signaling pathway; Focal adhesion; Hepatocyte growth factor receptor signaling; IL6 signaling pathway; BDNF-TrkB signaling; Physico-chemical features and toxicity-associated pathways; MAPK signaling pathway; T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection; 4-hydroxytamoxifen, dexamethasone, and retinoic acids regulation of p27 expression; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Chemokine signaling pathway; Embryonic stem cell pluripotency pathways; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Endometrial cancer; PI3K-Akt signaling pathway; Chromosomal and microsatellite instability in colorectal cancer ; MAPK cascade; Ras signaling; Epithelial to mesenchymal transition in colorectal cancer; Non-small cell lung cancer; Breast cancer pathway; Pancreatic adenocarcinoma pathway; Ethanol metabolism production of ROS by CYP2E1; EGF/EGFR signaling pathway; Envelope proteins and their potential roles in EDMD physiopathology; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Gastrin signaling pathway; Hepatitis B infection; Melanoma; Netrin-UNC5B signaling pathway; FGFR3 signaling in chondrocyte proliferation and terminal differentiation; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; Kisspeptin/kisspeptin receptor system in the ovary; Host-pathogen interaction of human coronaviruses - MAPK signaling; IL-2 signaling pathway; MAPK pathway in congenital thyroid cancer; Pleural mesothelioma; Regulation of actin cytoskeleton; Alzheimer's disease; GDNF signaling; A network map of Macrophage-stimulating protein (MSP) signaling; EPO receptor signaling; ErbB signaling pathway; T-cell receptor signaling pathway; Estrogen signaling pathway; Serotonin HTR1 group and FOS pathway; Serotonin receptor 2 and ELK-SRF/GATA4 signaling; Serotonin receptor 4/6/7 and NR3C signaling; Toll-like receptor signaling pathway"	"Signaling by BRAF and RAF1 fusions; Uptake and function of anthrax toxins; Signal transduction by L1; RAF activation; MAP3K8 (TPL2)-dependent MAPK1/3 activation; MAPK3 (ERK1) activation; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; Frs2-mediated activation; Negative feedback regulation of MAPK pathway; Signaling by MAP2K mutants"	"96"	"0"	"20.5"	"23.7"	"25.9"	"25.5"	"20.3"	"17.4"	"26.9"	"45.8"	"103.5"	"360.4"	"869.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P28072"	"Proteasome subunit beta type-6 OS=Homo sapiens OX=9606 GN=PSMB6 PE=1 SV=4"	"8"	"2"	"3"	"2"	"239"	"25.3"	"4.92"	"335.26"	"6.29"	"1"	"2"	"protein metabolism;other metabolic processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00227"	"5694"	"ENSG00000142507"	"PSMB6"	"hsa:5694; P28072; Q96J55"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Regulation of expression of SLITs and ROBOs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"62"	"0"	"84.8"	"82.3"	"102.9"	"109.2"	"111.9"	"119.4"	"138.5"	"150.5"	"251.5"	"495.9"	"977.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8ND56"	"Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3"	"10"	"4"	"6"	"3"	"463"	"50.5"	"9.52"	"1139.30"	"6.28"	"3"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;signal transduction;other biological processes"	"cytosol;cytoskeleton;other cell component"	"nucleic acid binding activity"	"Pf09532, Pf12701"	"26065"	"ENSG00000257103; ENSG00000262860"	"LSM14A"	"B4DTG6; hsa:26065; Q76LX7; Q8ND56; Q96AR3; Q96K73; Q96SN5; Q9UFR3"	""	""	"0"	"0"	"178.0"	"174.9"	"208.4"	"170.2"	"211.6"	"198.3"	"210.4"	"238.2"	"392.1"	"619.6"	"887.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NR56"	"Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2"	"7"	"2"	"3"	"2"	"388"	"41.8"	"8.90"	"255.56"	"6.28"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00642, Pf14608"	"4154"	"ENSG00000152601"	"MBNL1"	"E9PBW7; hsa:4154; O43311; O43797; Q86UV8; Q86UV9; Q96P92; Q96RE3; Q9NR56"	"Adipogenesis"	""	"1"	"0"	"117.0"	"110.3"	"139.7"	"106.8"	"128.9"	"86.8"	"138.3"	"166.2"	"226.8"	"421.2"	"581.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NP79"	"Vacuolar protein sorting-associated protein VTA1 homolog OS=Homo sapiens OX=9606 GN=VTA1 PE=1 SV=1"	"9"	"2"	"4"	"2"	"307"	"33.9"	"6.29"	"693.39"	"6.27"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	""	"Pf04652, Pf18097"	"51534"	"ENSG00000009844"	"VTA1"	"B4DW55; E1P594; E7ETQ7; hsa:51534; Q5TGM1; Q6IAE8; Q9H0R2; Q9H3K9; Q9NP79; Q9P0Q0"	""	"Endosomal Sorting Complex Required For Transport (ESCRT); Budding and maturation of HIV virion"	"2"	"0"	"54.9"	"56.9"	"67.0"	"53.7"	"63.0"	"61.0"	"84.6"	"81.8"	"132.0"	"474.1"	"1170.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UQ13"	"Leucine-rich repeat protein SHOC-2 OS=Homo sapiens OX=9606 GN=SHOC2 PE=1 SV=2"	"6"	"2"	"2"	"2"	"582"	"64.8"	"8.46"	"372.18"	"6.26"	"1"	"1"	"signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf13855"	"8036"	"ENSG00000108061"	"SHOC2"	"A8K9W8; B3KR23; hsa:8036; O76063; Q5VZS8; Q5VZS9; Q9UQ13"	"Ras signaling; 22q11.2 copy number variation syndrome; Autophagy in pancreatic ductal adenocarcinoma"	"RAF activation; SHOC2 M1731 mutant abolishes MRAS complex function; Gain-of-function MRAS complexes activate RAF signaling"	"6"	"0"	"15.8"	"16.8"	"20.5"	"18.8"	"22.4"	"18.4"	"20.6"	"34.9"	"75.7"	"129.1"	"126.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13136"	"Liprin-alpha-1 OS=Homo sapiens OX=9606 GN=PPFIA1 PE=1 SV=1"	"5"	"5"	"7"	"3"	"1202"	"135.7"	"6.29"	"1924.34"	"6.23"	"5"	"2"	"cell adhesion;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;other cell component"	""	"Pf00536, Pf07647"	"8500"	"ENSG00000131626"	"PPFIA1"	"A6NLE3; hsa:8500; Q13135; Q13136; Q14567; Q8N4I2"	""	"Glutamate Neurotransmitter Release Cycle; Serotonin Neurotransmitter Release Cycle; Norepinephrine Neurotransmitter Release Cycle; Dopamine Neurotransmitter Release Cycle; Acetylcholine Neurotransmitter Release Cycle; Receptor-type tyrosine-protein phosphatases"	"6"	"0"	"179.4"	"171.6"	"188.1"	"158.3"	"179.6"	"211.1"	"212.9"	"287.9"	"403.0"	"597.9"	"873.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UQ16"	"Dynamin-3 OS=Homo sapiens OX=9606 GN=DNM3 PE=1 SV=4"	"3"	"3"	"6"	"1"	"869"	"97.7"	"8.35"	"1437.62"	"6.21"	"3"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytoskeleton;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00169, Pf00350, Pf01031, Pf02212"	"26052"	"ENSG00000197959"	"DNM3"	"A9Z1Y1; hsa:26052; O14982; O95555; Q1MTM8; Q5W129; Q6P2G1; Q9H0P3; Q9H548; Q9NQ68; Q9NQN6; Q9UQ16"	"Synaptic vesicle pathway; Alstrom syndrome; 15q25 copy number variation"	"Recycling pathway of L1; MHC class II antigen presentation; Toll Like Receptor 4 (TLR4) Cascade; Clathrin-mediated endocytosis; Retrograde neurotrophin signalling"	"8"	"0"	"6.1"	"5.7"	"9.3"	"16.3"	"12.8"	"15.4"	"27.4"	"48.5"	"114.3"	"126.0"	"157.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00541"	"Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1"	"4"	"2"	"4"	"2"	"588"	"68.0"	"7.33"	"647.37"	"6.21"	"2"	"2"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf06732, Pf16589"	"23481"	"ENSG00000100029"	"PES1"	"hsa:23481; O00541; Q6IC29"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"60.9"	"57.4"	"56.5"	"40.4"	"56.1"	"46.8"	"59.4"	"84.3"	"83.7"	"89.5"	"186.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKN8"	"General transcription factor 3C polypeptide 4 OS=Homo sapiens OX=9606 GN=GTF3C4 PE=1 SV=2"	"3"	"2"	"2"	"2"	"822"	"91.9"	"6.65"	""	"6.18"	""	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf12657, Pf12660, Pf19336"	"9329"	"ENSG00000125484"	"GTF3C4"	"hsa:9329; Q5VZJ7; Q9UKN8"	""	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter"	"3"	"0"	"16.2"	"13.1"	"20.5"	"8.1"	"17.4"	"13.0"	"21.5"	"29.0"	"53.9"	"165.2"	"299.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13825"	"Methylglutaconyl-CoA hydratase, mitochondrial OS=Homo sapiens OX=9606 GN=AUH PE=1 SV=1"	"6"	"2"	"4"	"2"	"339"	"35.6"	"9.48"	"755.83"	"6.17"	"2"	"2"	"other metabolic processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00378"	"549"	"ENSG00000148090"	"AUH"	"B1ALV7; B1ALV8; hsa:549; Q13825; Q8WUE4"	"Amino acid metabolism"	"Branched-chain amino acid catabolism"	"2"	"0"	"144.8"	"122.0"	"161.7"	"150.6"	"160.9"	"163.8"	"191.4"	"157.9"	"149.3"	"221.3"	"304.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5D862"	"Filaggrin-2 OS=Homo sapiens OX=9606 GN=FLG2 PE=1 SV=1"	"0"	"1"	"4"	"1"	"2391"	"247.9"	"8.31"	"602.67"	"6.17"	"1"	"1"	"cell adhesion;other biological processes"	"non-structural extracellular;plasma membrane;other cell component"	"other molecular function"	"Pf01023"	"388698"	"ENSG00000143520"	"FLG2"	"hsa:388698; Q5D862; Q9H4U1"	""	"Neutrophil degranulation"	"1"	"0"	"17.1"	"48.7"	"54.9"	"47.6"	"85.8"	"23.6"	"37.2"	"236.4"	"121.5"	"384.7"	"222.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P265"	"Disco-interacting protein 2 homolog B OS=Homo sapiens OX=9606 GN=DIP2B PE=1 SV=3"	"2"	"2"	"3"	"2"	"1576"	"171.4"	"8.09"	"396.56"	"6.17"	"1"	"2"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"cytoskeletal activity"	"Pf00501, Pf06464"	"57609"	"ENSG00000066084"	"DIP2B"	"hsa:57609; Q6B011; Q8N1L5; Q8NB38; Q9P265"	""	""	"0"	"0"	"40.2"	"27.2"	"44.7"	"38.3"	"40.9"	"34.2"	"43.1"	"53.6"	"106.7"	"146.6"	"199.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15047"	"Histone-lysine N-methyltransferase SETD1A OS=Homo sapiens OX=9606 GN=SETD1A PE=1 SV=3"	"1"	"1"	"1"	"1"	"1707"	"185.9"	"5.14"	""	"6.16"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00856, Pf11764"	"9739"	"ENSG00000099381"	"SETD1A"	"A6NP62; hsa:9739; O15047; Q6PIF3; Q8TAJ6"	"Histone modifications"	"Formation of WDR5-containing histone-modifying complexes; PKMTs methylate histone lysines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"	"4"	"0"	"21.7"	"29.1"	"34.4"	"25.8"	"31.9"	"31.2"	"39.3"	"50.7"	"68.4"	"140.0"	"229.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99538"	"Legumain OS=Homo sapiens OX=9606 GN=LGMN PE=1 SV=1"	"6"	"1"	"1"	"1"	"433"	"49.4"	"6.55"	""	"6.15"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01650"	"5641"	"ENSG00000100600"	"LGMN"	"hsa:5641; O00123; Q86TV2; Q86TV3; Q99538; Q9BTY1"	"Involvement of d-secretase in neurodegenerative diseases"	"MHC class II antigen presentation; Trafficking and processing of endosomal TLR; Vitamin D (calciferol) metabolism"	"4"	"0"	"17.3"	"19.6"	"18.0"	"13.9"	"18.2"	"21.7"	"25.1"	"35.6"	"89.8"	"197.5"	"336.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15813"	"Tubulin-specific chaperone E OS=Homo sapiens OX=9606 GN=TBCE PE=1 SV=1"	"6"	"2"	"3"	"2"	"527"	"59.3"	"6.76"	"332.41"	"6.12"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01302, Pf14560"	"6905"	"ENSG00000282984; ENSG00000284770; ENSG00000285053"	"TBCE"	"A8K8C2; B7Z3P1; hsa:6905; Q15813"	""	"Post-chaperonin tubulin folding pathway"	"1"	"0"	"14.9"	"13.1"	"17.4"	"14.1"	"22.8"	"15.2"	"15.6"	"28.5"	"54.7"	"172.6"	"472.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95573"	"Long-chain-fatty-acid--CoA ligase 3 OS=Homo sapiens OX=9606 GN=ACSL3 PE=1 SV=3"	"3"	"2"	"4"	"1"	"720"	"80.4"	"8.38"	"622.11"	"6.09"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00501"	"2181"	"ENSG00000123983"	"ACSL3"	"hsa:2181; O95573; Q60I92; Q8IUM9"	"Fatty acid beta-oxidation; Fatty acid biosynthesis; Mitochondrial long chain fatty acid beta-oxidation; PPAR signaling pathway; Ferroptosis; Thermogenesis; Ciliary landscape; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Omega-3 / omega-6 fatty acid synthesis; Omega-9 fatty acid synthesis; Fatty acid transporters; Mitochondrial fatty acid oxidation disorders"	"Synthesis of very long-chain fatty acyl-CoAs; Intracellular metabolism of fatty acids regulates insulin secretion"	"14"	"1"	"159.5"	"177.5"	"139.0"	"131.7"	"140.2"	"155.4"	"183.0"	"257.8"	"585.4"	"945.9"	"1000.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P00390"	"Glutathione reductase, mitochondrial OS=Homo sapiens OX=9606 GN=GSR PE=1 SV=2"	"4"	"2"	"2"	"2"	"522"	"56.2"	"8.50"	""	"6.08"	""	"2"	"other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion"	"other molecular function"	"Pf00070, Pf02852"	"2936"	"ENSG00000104687"	"GSR"	"C8KIL8; C8KIL9; C8KIM0; D3DSV3; hsa:2936; P00390; Q7Z5C9; Q9NP63"	"Glutathione metabolism; Selenium micronutrient network; Trans-sulfuration, one-carbon metabolism and related pathways; Nuclear receptors meta-pathway; NRF2 pathway; Amino acid metabolism; Oxidative stress response; Vitamin D-sensitive calcium signaling in depression; Sulfation biotransformation reaction; Metapathway biotransformation Phase I and II"	""	"10"	"0"	"16.5"	"16.5"	"23.1"	"21.3"	"25.2"	"28.1"	"27.8"	"43.7"	"88.9"	"241.2"	"420.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13601"	"KRR1 small subunit processome component homolog OS=Homo sapiens OX=9606 GN=KRR1 PE=1 SV=4"	"8"	"4"	"6"	"4"	"381"	"43.6"	"9.77"	"1636.13"	"6.07"	"4"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf17903"	"11103"	"ENSG00000111615"	"KRR1"	"A0FIK6; A0JLP0; B2R989; E7EUQ0; hsa:11103; Q13601; Q8NEA8; Q8TC37; Q96AT5"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"377.2"	"308.9"	"334.0"	"309.2"	"358.6"	"371.3"	"411.2"	"517.4"	"982.5"	"1504.3"	"1832.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55145"	"Mesencephalic astrocyte-derived neurotrophic factor OS=Homo sapiens OX=9606 GN=MANF PE=1 SV=3"	"16"	"4"	"6"	"4"	"182"	"20.7"	"8.69"	"1631.63"	"6.07"	"4"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf10208, Pf20145"	"7873"	"ENSG00000145050"	"MANF"	"hsa:7873; P55145; Q14CX4; Q86U67; Q96IS4"	"Orexin receptor pathway"	"Platelet degranulation"	"2"	"0"	"265.5"	"248.2"	"308.0"	"257.9"	"327.3"	"285.1"	"452.1"	"916.0"	"2402.1"	"2749.4"	"2727.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50613"	"Cyclin-dependent kinase 7 OS=Homo sapiens OX=9606 GN=CDK7 PE=1 SV=1"	"8"	"2"	"4"	"2"	"346"	"39.0"	"8.47"	"693.95"	"6.05"	"2"	"2"	"cell cycle OR cell proliferation;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"1022"	"ENSG00000134058; ENSG00000277273"	"CDK7"	"hsa:1022; P50613; Q9BS60; Q9UE19"	"MicroRNAs in cardiomyocyte hypertrophy; Cell cycle; Cardiac hypertrophic response; Eukaryotic transcription initiation; G1 to S cell cycle control; Nucleotide excision repair; DNA repair pathways, full network; Pleural mesothelioma; Nucleotide excision repair in xeroderma pigmentosum"	"RUNX1 regulates transcription of genes involved in differentiation of HSCs; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; Cyclin D associated events in G1; Cyclin A/B1/B2 associated events during G2/M transition; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Cyclin E associated events during G1/S transition ; Cyclin A:Cdk2-associated events at S phase entry"	"43"	"0"	"59.4"	"67.4"	"100.0"	"59.9"	"60.4"	"61.5"	"74.5"	"104.5"	"300.0"	"434.8"	"658.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NDT2"	"Putative RNA-binding protein 15B OS=Homo sapiens OX=9606 GN=RBM15B PE=1 SV=3"	"3"	"2"	"4"	"1"	"890"	"97.1"	"9.85"	"656.33"	"6.05"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf07744"	"29890"	"ENSG00000259956"	"RBM15B"	"A4QPG7; hsa:29890; Q6QE19; Q8NDT2; Q9BV96"	""	""	"0"	"0"	"75.9"	"83.3"	"61.2"	"63.0"	"73.4"	"69.1"	"91.7"	"110.6"	"164.5"	"260.9"	"371.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P53680"	"AP-2 complex subunit sigma OS=Homo sapiens OX=9606 GN=AP2S1 PE=1 SV=2"	"15"	"2"	"3"	"2"	"142"	"17.0"	"6.18"	"348.00"	"6.04"	"1"	"2"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01217"	"1175"	"ENSG00000042753"	"AP2S1"	"B2R4Z4; hsa:1175; O75977; P53680; Q6PK67"	"Synaptic vesicle pathway; VEGFA-VEGFR2 signaling; GABA receptor signaling; EGF/EGFR signaling pathway; Fragile X syndrome"	"MHC class II antigen presentation; Potential therapeutics for SARS; Recycling pathway of L1; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; LDL clearance; Nef Mediated CD4 Down-regulation; Retrograde neurotrophin signalling; Nef Mediated CD8 Down-regulation; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; VLDLR internalisation and degradation"	"18"	"0"	"30.3"	"31.5"	"32.0"	"30.9"	"35.7"	"49.5"	"55.9"	"89.4"	"147.4"	"225.8"	"256.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q02040"	"A-kinase anchor protein 17A OS=Homo sapiens OX=9606 GN=AKAP17A PE=1 SV=2"	"3"	"2"	"4"	"2"	"695"	"80.7"	"9.73"	"641.98"	"6.04"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus"	"other molecular function"	""	"8227"	"ENSG00000197976"	"AKAP17A"	"hsa:8227; Q02040; Q02832; Q2TB98; Q5JQ74; Q5JQ76; Q8N6U9"	""	""	"0"	"0"	"86.1"	"101.1"	"107.7"	"85.4"	"91.1"	"88.2"	"122.1"	"196.6"	"621.2"	"915.9"	"988.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IXI1"	"Mitochondrial Rho GTPase 2 OS=Homo sapiens OX=9606 GN=RHOT2 PE=1 SV=2"	"4"	"2"	"4"	"2"	"618"	"68.1"	"5.86"	"640.32"	"6.04"	"2"	"2"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf00071, Pf08355, Pf08356"	"89941"	"ENSG00000140983"	"RHOT2"	"A2IDC2; hsa:89941; Q8IXI1; Q8NF53; Q96C13; Q96S17; Q9BT60; Q9H7M8"	""	"RHOT2 GTPase cycle"	"1"	"0"	"48.6"	"58.1"	"50.4"	"41.1"	"45.2"	"42.4"	"64.7"	"90.0"	"157.4"	"250.9"	"323.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HB21"	"Pleckstrin homology domain-containing family A member 1 OS=Homo sapiens OX=9606 GN=PLEKHA1 PE=1 SV=2"	"5"	"2"	"4"	"2"	"404"	"45.5"	"8.56"	"750.92"	"6.03"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00169"	"59338"	"ENSG00000107679"	"PLEKHA1"	"B3KQ55; D3DRE2; hsa:59338; Q9BVK0; Q9HB21"	""	"Synthesis of PIPs at the plasma membrane"	"1"	"0"	"31.9"	"29.7"	"30.1"	"32.4"	"55.6"	"51.7"	"94.8"	"185.3"	"318.2"	"357.5"	"333.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19823"	"Inter-alpha-trypsin inhibitor heavy chain H2 OS=Homo sapiens OX=9606 GN=ITIH2 PE=1 SV=2"	"1"	"1"	"4"	"1"	"946"	"106.4"	"6.86"	"658.74"	"6.03"	"1"	"1"	"other metabolic processes;other biological processes"	"non-structural extracellular;ER/Golgi"	"enzyme regulator activity;other molecular function"	"Pf00092, Pf06668, Pf08487"	"3698"	"ENSG00000151655"	"ITIH2"	"hsa:3698; P19823; Q14659; Q15484; Q5T986"	""	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation"	"2"	"0"	"7.3"	"6.5"	"8.1"	"6.5"	"8.3"	"9.7"	"10.6"	"10.2"	"17.9"	"61.2"	"103.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52926"	"High mobility group protein HMGI-C OS=Homo sapiens OX=9606 GN=HMGA2 PE=1 SV=1"	"38"	"2"	"3"	"2"	"109"	"11.8"	"10.62"	"819.42"	"6.03"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02178"	"8091"	"ENSG00000149948"	"HMGA2"	"E7EP85; E7EWA2; hsa:8091; P52926; Q1M182; Q1M185; Q1M186; Q1M187; Q1M188"	"Mesodermal commitment pathway; Mesodermal commitment pathway; Influence of laminopathies on Wnt signaling; Overlap between signal transduction pathways contributing to LMNA laminopathies; Orexin receptor pathway"	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"	"6"	"0"	"85.3"	"74.7"	"70.3"	"71.8"	"80.2"	"88.3"	"93.1"	"95.0"	"154.8"	"259.0"	"339.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95229"	"ZW10 interactor OS=Homo sapiens OX=9606 GN=ZWINT PE=1 SV=2"	"8"	"1"	"1"	"1"	"277"	"31.3"	"5.15"	""	"6.03"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf15556"	"11130"	"ENSG00000122952"	"ZWINT"	"A6NNV6; hsa:11130; O95229; Q0D2I3; Q9BWD0"	""	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"6"	"0"	"5.8"	"3.8"	"5.6"	"3.9"	"4.1"	"5.4"	"4.4"	"9.8"	"33.2"	"42.5"	"49.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5VWN6"	"Protein TASOR 2 OS=Homo sapiens OX=9606 GN=TASOR2 PE=1 SV=1"	"1"	"2"	"4"	"2"	"2430"	"268.7"	"5.90"	"843.91"	"6.02"	"2"	"2"	"cell organization and biogenesis"	"cytosol;nucleus"	""	"Pf12480, Pf12509"	"54906"	"ENSG00000108021"	"TASOR2"	"hsa:54906; Q2YD91; Q5VWN5; Q5VWN6; Q6ZRQ8; Q8IVG4; Q9BUZ7; Q9H5J9; Q9H7A4; Q9H996; Q9NXA1"	""	""	"0"	"0"	"64.3"	"53.7"	"66.6"	"49.7"	"66.3"	"60.0"	"74.4"	"88.2"	"170.7"	"277.8"	"348.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NVI1"	"Fanconi anemia group I protein OS=Homo sapiens OX=9606 GN=FANCI PE=1 SV=4"	"2"	"2"	"4"	"2"	"1328"	"149.2"	"6.74"	"752.43"	"6.02"	"2"	"2"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf14674, Pf14675, Pf14676, Pf14677, Pf14678, Pf14679, Pf14680"	"55215"	"ENSG00000140525"	"FANCI"	"A4ZVE4; A5YMH4; A6NJZ0; hsa:55215; Q96JN1; Q96ST0; Q9BT96; Q9NVI1"	"Gastric cancer network 2; DNA repair pathways, full network; 15q11q13 copy number variation"	"TP53 Regulates Transcription of DNA Repair Genes; Fanconi Anemia Pathway"	"5"	"0"	"36.7"	"43.2"	"34.0"	"28.8"	"26.1"	"33.0"	"40.2"	"64.3"	"272.3"	"472.7"	"582.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15276"	"Rab GTPase-binding effector protein 1 OS=Homo sapiens OX=9606 GN=RABEP1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"862"	"99.2"	"5.01"	"599.67"	"6.02"	"1"	"1"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"other membranes;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf03528, Pf09311"	"9135"	"ENSG00000029725"	"RABEP1"	"B2RAG7; hsa:9135; O95369; Q15276; Q8IVX3"	"GDNF signaling"	"TBC/RABGAPs"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86T24"	"Transcriptional regulator Kaiso OS=Homo sapiens OX=9606 GN=ZBTB33 PE=1 SV=2"	"3"	"1"	"2"	"1"	"672"	"74.4"	"5.12"	"517.21"	"6.02"	"1"	"1"	"cell-cell signaling;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00651"	"10009"	"ENSG00000177485"	"ZBTB33"	"B2R5U6; hsa:10009; O00319; Q7Z361; Q86T24; Q8IVP6; Q8N3P0"	"Wnt signaling pathway and pluripotency"	""	"1"	"0"	"70.0"	"75.2"	"92.4"	"76.0"	"92.7"	"62.4"	"102.2"	"115.5"	"133.4"	"201.5"	"249.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IWS0"	"PHD finger protein 6 OS=Homo sapiens OX=9606 GN=PHF6 PE=1 SV=1"	"6"	"2"	"2"	"2"	"365"	"41.3"	"8.68"	""	"6.01"	""	"2"	"developmental processes;other biological processes"	"nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf13771"	"84295"	"ENSG00000156531"	"PHF6"	"A8K230; B4E0G4; D3DTG3; E9PC97; hsa:84295; Q5JRC7; Q5JRC8; Q8IWS0; Q96JK3; Q9BRU0"	"Mesodermal commitment pathway"	""	"1"	"0"	"138.1"	"100.4"	"152.8"	"125.1"	"150.9"	"176.8"	"193.7"	"239.3"	"703.8"	"984.7"	"998.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IWZ6"	"Bardet-Biedl syndrome 7 protein OS=Homo sapiens OX=9606 GN=BBS7 PE=1 SV=2"	"4"	"2"	"4"	"2"	"715"	"80.3"	"6.05"	"625.15"	"6.01"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	""	"55212"	"ENSG00000138686"	"BBS7"	"hsa:55212; Q4W5P8; Q8IWZ6; Q8N581; Q9NVI4"	"Ciliary landscape; Genes related to primary cilium development (based on CRISPR); Joubert syndrome; Ciliopathies; Bardet-Biedl syndrome"	"BBSome-mediated cargo-targeting to cilium"	"6"	"0"	"3.8"	"2.2"	"5.7"	"5.1"	"6.1"	"6.8"	"9.3"	"6.3"	"17.9"	"37.5"	"46.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BTT4"	"Mediator of RNA polymerase II transcription subunit 10 OS=Homo sapiens OX=9606 GN=MED10 PE=1 SV=1"	"10"	"1"	"2"	"1"	"135"	"15.7"	"6.19"	""	"6.00"	""	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf09748"	"84246"	"ENSG00000133398"	"MED10"	"C6G491; hsa:84246; Q9BTT4"	""	"PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; Generic Transcription Pathway"	"3"	"0"	"38.4"	"44.5"	"54.5"	"39.1"	"58.4"	"52.0"	"59.4"	"77.9"	"133.9"	"273.1"	"441.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6PJT7"	"Zinc finger CCCH domain-containing protein 14 OS=Homo sapiens OX=9606 GN=ZC3H14 PE=1 SV=1"	"2"	"2"	"3"	"2"	"736"	"82.8"	"7.31"	"926.38"	"5.99"	"2"	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf14608"	"79882"	"ENSG00000100722"	"ZC3H14"	"A8MY46; B4DXU8; B4DZW7; B4E2H4; G3V5R4; hsa:79882; Q6MZU4; Q6PJ32; Q6PJT7; Q6PUI6; Q6PUI8; Q86TQ5; Q86TW0; Q86TW1; Q8NCT6; Q8NCZ3; Q8TDE2; Q9HAC9; Q9Y5A0"	""	""	"0"	"0"	"41.5"	"41.9"	"38.4"	"46.3"	"50.6"	"40.2"	"51.5"	"57.8"	"67.6"	"107.1"	"152.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P16403"	"Histone H1.2 OS=Homo sapiens OX=9606 GN=H1-2 PE=1 SV=2"	"19"	"4"	"6"	"4"	"213"	"21.4"	"10.93"	"1636.82"	"5.99"	"4"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00538"	"3006"	"ENSG00000187837"	"H1-2"	"A8K4I2; hsa:3006; P16403"	""	"Apoptosis induced DNA fragmentation; Formation of Senescence-Associated Heterochromatin Foci (SAHF)"	"2"	"0"	"510.4"	"517.8"	"506.0"	"411.8"	"492.0"	"518.7"	"631.3"	"784.6"	"1272.2"	"2131.2"	"3304.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99417"	"c-Myc-binding protein OS=Homo sapiens OX=9606 GN=MYCBP PE=1 SV=3"	"19"	"1"	"2"	"1"	"103"	"12.0"	"5.91"	"595.56"	"5.99"	"1"	"1"	"other biological processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	""	"26292"	"ENSG00000214114"	"MYCBP"	"B2R4N0; hsa:26292; Q5TA64; Q96HE2; Q99417"	"Pathways affected in adenoid cystic carcinoma"	""	"1"	"0"	"14.9"	"18.3"	"22.0"	"24.7"	"17.0"	"27.0"	"30.5"	"72.2"	"230.3"	"468.6"	"844.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14694"	"Ubiquitin carboxyl-terminal hydrolase 10 OS=Homo sapiens OX=9606 GN=USP10 PE=1 SV=2"	"3"	"1"	"2"	"1"	"798"	"87.1"	"5.31"	"672.81"	"5.99"	"1"	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00443, Pf07145"	"9100"	"ENSG00000103194"	"USP10"	"B2RDJ8; B4DS84; hsa:9100; Q14694; Q9BWG7; Q9NSL7"	"VEGFA-VEGFR2 signaling"	"Ub-specific processing proteases; Termination of translesion DNA synthesis"	"3"	"0"	"27.8"	"18.7"	"34.9"	"24.5"	"31.9"	"26.7"	"30.0"	"44.6"	"79.9"	"164.4"	"251.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14643"	"Inositol 1,4,5-trisphosphate receptor type 1 OS=Homo sapiens OX=9606 GN=ITPR1 PE=1 SV=3"	"1"	"3"	"5"	"1"	"2758"	"313.7"	"6.04"	"870.01"	"5.98"	"3"	"2"	"cell-cell signaling;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf00520, Pf01365, Pf02815, Pf08454, Pf08709"	"3708"	"ENSG00000150995"	"ITPR1"	"E7EPX7; E9PDE9; hsa:3708; Q14643; Q14660; Q99897"	"Alzheimer's disease and miRNA effects; Myometrial relaxation and contraction pathways; G protein signaling pathways; Cell-type dependent selectivity of CCK2R signaling; Resistin as a regulator of inflammation; Fragile X syndrome; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Vitamin D-sensitive calcium signaling in depression; PKC-gamma calcium signaling pathway in ataxia; Type I collagen synthesis in the context of osteogenesis imperfecta; GPR143 in melanocytes and retinal pigment epithelium cells; STING pathway in Kawasaki-like disease and COVID-19; Alzheimer's disease; GDNF signaling; Calcium regulation in cardiac cells; 15q25 copy number variation; T-cell receptor signaling pathway; Serotonin HTR1 group and FOS pathway; Serotonin receptor 2 and ELK-SRF/GATA4 signaling"	"Ca2+ pathway; Role of phospholipids in phagocytosis; FCGR3A-mediated IL10 synthesis; VEGFR2 mediated cell proliferation; DAG and IP3 signaling; Effects of PIP2 hydrolysis; FCERI mediated Ca+2 mobilization; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Ion homeostasis; cGMP effects; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Elevation of cytosolic Ca2+ levels; PLC beta mediated events; CLEC7A (Dectin-1) induces NFAT activation"	"34"	"0"	"12.2"	"15.5"	"21.5"	"13.7"	"17.6"	"11.1"	"14.1"	"17.0"	"60.3"	"137.9"	"180.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4Y9"	"U6 snRNA-associated Sm-like protein LSm5 OS=Homo sapiens OX=9606 GN=LSM5 PE=1 SV=3"	"25"	"1"	"1"	"1"	"91"	"9.9"	"4.54"	""	"5.97"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01423"	"23658"	"ENSG00000106355"	"LSM5"	"hsa:23658; Q9Y4Y9"	""	"mRNA Splicing - Major Pathway; mRNA decay by 5' to 3' exoribonuclease"	"2"	"0"	"15.0"	"14.4"	"15.7"	"14.7"	"16.8"	"14.9"	"21.3"	"23.6"	"51.1"	"85.5"	"145.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P20585"	"DNA mismatch repair protein Msh3 OS=Homo sapiens OX=9606 GN=MSH3 PE=1 SV=4"	"3"	"3"	"5"	"3"	"1137"	"127.3"	"8.02"	"1272.34"	"5.97"	"3"	"2"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00488, Pf01624, Pf05188, Pf05192"	"4437"	"ENSG00000113318"	"MSH3"	"A1L480; A1L482; A6NMM6; hsa:4437; P20585; Q6PJT5; Q86UQ6; Q92867"	"Chromosomal and microsatellite instability in colorectal cancer ; DNA repair pathways, full network"	"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta); Defective Mismatch Repair Associated With MSH3; Defective Mismatch Repair Associated With MSH2"	"5"	"0"	"73.8"	"81.2"	"86.4"	"71.0"	"73.0"	"74.2"	"110.3"	"116.2"	"189.2"	"250.1"	"333.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NFY9"	"Kelch repeat and BTB domain-containing protein 8 OS=Homo sapiens OX=9606 GN=KBTBD8 PE=1 SV=2"	"6"	"3"	"5"	"3"	"601"	"68.8"	"6.29"	"1080.44"	"5.97"	"3"	"2"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;other cell component"	""	"Pf00651, Pf01344, Pf07707"	"84541"	"ENSG00000163376"	"KBTBD8"	"B4DTW6; hsa:84541; Q8NFY9; Q96JI5"	""	"Antigen processing: Ubiquitination & Proteasome degradation; Neddylation"	"2"	"0"	"44.7"	"37.4"	"45.4"	"44.6"	"46.4"	"51.8"	"85.8"	"153.8"	"299.8"	"426.5"	"534.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43670"	"BUB3-interacting and GLEBS motif-containing protein ZNF207 OS=Homo sapiens OX=9606 GN=ZNF207 PE=1 SV=1"	"4"	"2"	"3"	"2"	"478"	"50.7"	"9.10"	"434.10"	"5.96"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	""	"7756"	"ENSG00000010244"	"ZNF207"	"A8K6Y6; E1P660; E1P661; E1P662; hsa:7756; O43670; Q53XS9; Q96HW5; Q9BUQ7"	""	""	"0"	"0"	"173.3"	"143.2"	"172.2"	"163.4"	"181.4"	"146.5"	"195.0"	"248.8"	"452.4"	"661.7"	"831.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31151"	"Protein S100-A7 OS=Homo sapiens OX=9606 GN=S100A7 PE=1 SV=4"	"43"	"3"	"5"	"3"	"101"	"11.5"	"6.77"	"1099.81"	"5.96"	"3"	"2"	"stress response;developmental processes;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01023"	"6278"	"ENSG00000143556"	"S100A7"	"hsa:6278; P31151; Q5SY67; Q6FGE3; Q9H1E2"	""	"Neutrophil degranulation; Metal sequestration by antimicrobial proteins"	"2"	"0"	"62.6"	"96.9"	"117.1"	"138.0"	"94.9"	"62.4"	"72.4"	"340.9"	"355.7"	"379.0"	"381.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2L5"	"Trafficking protein particle complex subunit 8 OS=Homo sapiens OX=9606 GN=TRAPPC8 PE=1 SV=2"	"2"	"2"	"2"	"2"	"1435"	"160.9"	"6.87"	""	"5.95"	""	"2"	"cell organization and biogenesis;transport"	"cytosol;ER/Golgi;other cell component"	""	"Pf12739"	"22878"	"ENSG00000153339"	"TRAPPC8"	"A0JP15; B3KME5; hsa:22878; Q9H0L2; Q9Y2L5"	""	"RAB GEFs exchange GTP for GDP on RABs"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07737"	"Profilin-1 OS=Homo sapiens OX=9606 GN=PFN1 PE=1 SV=2"	"17"	"2"	"4"	"2"	"140"	"15.0"	"8.27"	"623.29"	"5.95"	"2"	"2"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00235"	"5216"	"ENSG00000108518"	"PFN1"	"hsa:5216; P07737; Q53Y44"	"Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; Burn wound healing; Regulation of actin cytoskeleton; G13 signaling pathway"	"RHO GTPases Activate Formins; Platelet degranulation ; PCP/CE pathway; Signaling by ROBO receptors"	"9"	"0"	"86.9"	"131.9"	"132.2"	"142.4"	"91.5"	"73.5"	"105.5"	"156.4"	"266.0"	"468.8"	"637.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UHV9"	"Prefoldin subunit 2 OS=Homo sapiens OX=9606 GN=PFDN2 PE=1 SV=1"	"15"	"2"	"4"	"2"	"154"	"16.6"	"6.58"	"778.45"	"5.95"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01920"	"5202"	"ENSG00000143256"	"PFDN2"	"hsa:5202; Q9P0P7; Q9UHV9; Q9UN05"	"Cellular proteostasis"	"Prefoldin mediated transfer of substrate  to CCT/TriC"	"2"	"0"	"72.5"	"79.1"	"87.5"	"72.9"	"74.2"	"79.3"	"89.6"	"113.1"	"231.9"	"623.6"	"1016.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BRK5"	"45 kDa calcium-binding protein OS=Homo sapiens OX=9606 GN=SDF4 PE=1 SV=1"	"5"	"2"	"4"	"2"	"362"	"41.8"	"4.86"	"758.99"	"5.94"	"2"	"2"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf13202, Pf13499"	"51150"	""	"SDF4"	"B1AME5; B1AME6; B2RDF1; B4DSM1; hsa:51150; Q53G52; Q53HQ9; Q8NBQ3; Q96AA1; Q9BRK5; Q9NZP7; Q9UN53"	""	""	"0"	"0"	"119.1"	"98.1"	"137.6"	"123.3"	"145.6"	"146.5"	"150.5"	"174.9"	"273.4"	"394.2"	"477.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y617"	"Phosphoserine aminotransferase OS=Homo sapiens OX=9606 GN=PSAT1 PE=1 SV=2"	"5"	"2"	"2"	"2"	"370"	"40.4"	"7.66"	""	"5.94"	""	"2"	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00266"	"29968"	"ENSG00000135069"	"PSAT1"	"hsa:29968; Q5T7G5; Q5T7G6; Q96AW2; Q9BQ12; Q9Y617"	"Trans-sulfuration, one-carbon metabolism and related pathways; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Male infertility; Neuroinflammation and glutamatergic signaling; Amino acid metabolism in triple-negative breast cancer cells"	"Serine biosynthesis"	"7"	"0"	"31.2"	"44.5"	"49.1"	"43.9"	"40.8"	"36.8"	"54.1"	"71.9"	"137.6"	"343.9"	"1077.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y605"	"MORF4 family-associated protein 1 OS=Homo sapiens OX=9606 GN=MRFAP1 PE=1 SV=1"	"17"	"2"	"4"	"2"	"127"	"14.6"	"4.70"	"698.25"	"5.94"	"2"	"2"	""	"nucleus;other cell component"	""	"Pf15155"	"93621"	"ENSG00000179010"	"MRFAP1"	"B3KVT2; D3DVT3; hsa:93621; Q9Y605"	""	""	"0"	"0"	"127.9"	"135.2"	"169.4"	"141.7"	"150.2"	"133.5"	"146.1"	"192.1"	"278.2"	"343.0"	"407.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O76094"	"Signal recognition particle subunit SRP72 OS=Homo sapiens OX=9606 GN=SRP72 PE=1 SV=3"	"3"	"2"	"3"	"2"	"671"	"74.6"	"9.26"	"315.22"	"5.93"	"1"	"2"	"transport"	"cytosol;ER/Golgi;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf08492, Pf13181, Pf17004"	"6731"	"ENSG00000174780"	"SRP72"	"G5E9Z8; hsa:6731; O76094; Q7Z3C0"	""	"SRP-dependent cotranslational protein targeting to membrane"	"1"	"0"	"5.7"	"3.6"	"1.8"	"4.2"	"6.7"	"5.2"	"7.1"	"11.1"	"23.5"	"67.0"	"142.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13861"	"cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2"	"6"	"2"	"4"	"2"	"404"	"45.5"	"5.07"	"604.10"	"5.93"	"2"	"2"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00027, Pf02197"	"5576"	"ENSG00000114302"	"PRKAR2A"	"hsa:5576; P13861; Q16823; Q9BUB1"	"Myometrial relaxation and contraction pathways; G protein signaling pathways; Lipid metabolism pathway; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; GDNF signaling; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Factors involved in megakaryocyte development and platelet production; GPER1 signaling; FCGR3A-mediated IL10 synthesis; ADORA2B mediated anti-inflammatory cytokines production; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Vasopressin regulates renal water homeostasis via Aquaporins; PKA activation; PKA activation in glucagon signalling; Hedgehog 'off' state; DARPP-32 events; CREB1 phosphorylation through the activation of Adenylate Cyclase; ROBO receptors bind AKAP5"	"20"	"0"	"31.3"	"35.4"	"39.3"	"32.0"	"35.0"	"36.4"	"41.7"	"62.4"	"144.4"	"356.3"	"568.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P42338"	"Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform OS=Homo sapiens OX=9606 GN=PIK3CB PE=1 SV=1"	"3"	"2"	"3"	"2"	"1070"	"122.7"	"7.09"	"272.87"	"5.92"	"1"	"2"	"cell adhesion;cell cycle OR cell proliferation;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00454, Pf00613, Pf00792, Pf00794, Pf02192"	"5291"	"ENSG00000051382"	"PIK3CB"	"D3DNF0; hsa:5291; P42338; Q24JU2"	"AMP-activated protein kinase signaling; MicroRNAs in cardiomyocyte hypertrophy; Prolactin signaling pathway; Alzheimer's disease and miRNA effects; Glioblastoma signaling pathways; Focal adhesion; PI3K-AKT-mTOR signaling pathway and therapeutic opportunities in prostate cancer; Angiopoietin-like protein 8 regulatory pathway; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Microglia pathogen phagocytosis pathway; Endometrial cancer; PI3K-Akt signaling pathway; Ebola virus infection in host; Ras signaling; Epithelial to mesenchymal transition in colorectal cancer; Non-small cell lung cancer; Pancreatic adenocarcinoma pathway; Nonalcoholic fatty liver disease; Resistin as a regulator of inflammation; Relationship between inflammation, COX-2 and EGFR; Synaptic signaling pathways associated with autism spectrum disorder; Fragile X syndrome; Neural crest cell migration during development; Neural crest cell migration in cancer; Translation inhibitors in chronically activated PDGFRA cells; Cancer immunotherapy by CTLA4 blockade; Measles virus infection; Small cell lung cancer; Hepatitis B infection; Head and neck squamous cell carcinoma; Melanoma; Osteoblast differentiation and related diseases; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; mBDNF and proBDNF regulation of GABA neurotransmission; Kisspeptin/kisspeptin receptor system in the ovary; Pleural mesothelioma; Regulation of actin cytoskeleton; Alzheimer's disease; GDNF signaling; G13 signaling pathway; ErbB signaling pathway; DNA damage response (only ATM dependent); Toll-like receptor signaling pathway"	"Downstream TCR signaling; Nephrin family interactions; Regulation of signaling by CBL; Signaling by CSF1 (M-CSF) in myeloid cells; Role of phospholipids in phagocytosis; Role of LAT2/NTAL/LAB on calcium mobilization; PIP3 activates AKT signaling; Synthesis of PIPs at the plasma membrane; Constitutive Signaling by Aberrant PI3K in Cancer; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; RET signaling; Erythropoietin activates Phosphoinositide-3-kinase (PI3K); Interleukin receptor SHC signaling; RAF/MAP kinase cascade; PI3K Cascade; GPVI-mediated activation cascade; Downstream signal transduction; PI3K/AKT activation; Signaling by ALK; Tie2 Signaling; DAP12 signaling; VEGFA-VEGFR2 Pathway; Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants; Signaling by PDGFRA extracellular domain mutants"	"71"	"0"	"11.9"	"11.2"	"13.9"	"10.5"	"18.1"	"16.9"	"17.7"	"25.8"	"38.1"	"78.5"	"99.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31483"	"Nucleolysin TIA-1 isoform p40 OS=Homo sapiens OX=9606 GN=TIA1 PE=1 SV=3"	"7"	"3"	"5"	"1"	"386"	"42.9"	"7.74"	"785.39"	"5.92"	"3"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"7072"	"ENSG00000116001"	"TIA1"	"hsa:7072; P31483; Q53SS9; Q96B58"	""	"FGFR2 alternative splicing"	"1"	"0"	"219.8"	"238.6"	"193.5"	"182.7"	"214.5"	"205.1"	"222.5"	"253.7"	"258.3"	"304.2"	"370.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46779"	"60S ribosomal protein L28 OS=Homo sapiens OX=9606 GN=RPL28 PE=1 SV=3"	"11"	"2"	"4"	"2"	"137"	"15.7"	"12.02"	"600.89"	"5.91"	"2"	"2"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01778"	"6158"	"ENSG00000108107"	"RPL28"	"B2R4A6; B4DEP9; C9JB50; E9PB24; G5E9L2; hsa:6158; P46779; Q6IAY0; Q96FX1; Q9BWQ0"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"156.4"	"143.1"	"151.1"	"135.2"	"169.1"	"163.7"	"189.4"	"270.6"	"464.5"	"878.7"	"1559.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N9T8"	"Protein KRI1 homolog OS=Homo sapiens OX=9606 GN=KRI1 PE=1 SV=3"	"3"	"2"	"4"	"2"	"703"	"82.5"	"5.14"	"607.88"	"5.91"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf05178, Pf12936"	"65095"	"ENSG00000129347"	"KRI1"	"hsa:65095; Q2M1R5; Q2M1R7; Q7L5J7; Q8N9T8; Q96G92; Q9BU50; Q9H6I1; Q9H978"	""	""	"0"	"0"	"77.1"	"72.0"	"72.8"	"69.7"	"74.8"	"80.4"	"87.0"	"91.4"	"114.9"	"152.2"	"233.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P00505"	"Aspartate aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=GOT2 PE=1 SV=3"	"7"	"2"	"2"	"2"	"430"	"47.5"	"9.01"	"470.19"	"5.91"	"1"	"1"	"other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;mitochondrion"	"other molecular function"	"Pf00155"	"2806"	"ENSG00000125166"	"GOT2"	"B4DJA6; E7ERW2; hsa:2806; P00505; Q53FL3; Q9BWA3"	"Alanine and aspartate metabolism; Amino acid metabolism; Metabolic reprogramming in colon cancer; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"Glyoxylate metabolism and glycine degradation; Gluconeogenesis; Aspartate and asparagine metabolism; Glutamate and glutamine metabolism; Degradation of cysteine and homocysteine"	"11"	"0"	"264.1"	"228.7"	"329.2"	"357.2"	"263.3"	"326.0"	"413.7"	"427.7"	"589.2"	"669.7"	"1005.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2S7"	"Polymerase delta-interacting protein 2 OS=Homo sapiens OX=9606 GN=POLDIP2 PE=1 SV=1"	"6"	"2"	"4"	"2"	"368"	"42.0"	"8.63"	"723.91"	"5.90"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytoskeleton;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity"	"Pf04379, Pf08755"	"26073"	"ENSG00000004142"	"POLDIP2"	"B2R846; hsa:26073; Q96JE4; Q9Y2S7"	""	""	"0"	"0"	"118.6"	"107.2"	"103.3"	"106.6"	"112.1"	"121.5"	"125.8"	"149.0"	"219.5"	"383.5"	"879.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43242"	"26S proteasome non-ATPase regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PSMD3 PE=1 SV=2"	"4"	"1"	"1"	"1"	"534"	"60.9"	"8.44"	""	"5.89"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf01399, Pf08375"	"5709"	"ENSG00000108344"	"PSMD3"	"B3KMW9; B4DT72; hsa:5709; O43242; Q96EI2; Q9BQA4"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"64"	"0"	"9.1"	"11.8"	"15.9"	"9.7"	"14.6"	"15.5"	"14.2"	"25.1"	"39.2"	"86.0"	"139.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75396"	"Vesicle-trafficking protein SEC22b OS=Homo sapiens OX=9606 GN=SEC22B PE=1 SV=4"	"10"	"1"	"1"	"1"	"215"	"24.6"	"6.92"	""	"5.88"	""	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"15.5"	"15.5"	"19.0"	"16.7"	"24.0"	"14.0"	"27.3"	"33.1"	"73.2"	"187.8"	"251.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14739"	"Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2"	"3"	"2"	"4"	"2"	"615"	"70.7"	"9.36"	"672.53"	"5.86"	"2"	"2"	"other metabolic processes;other biological processes"	"other membranes;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01222, Pf09465"	"3930"	"ENSG00000143815"	"LBR"	"B2R5P3; hsa:3930; Q14739; Q14740; Q53GU7; Q59FE6"	"Gastric cancer network 2; ATM signaling in development and disease ; Envelope proteins and their potential roles in EDMD physiopathology; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Cholesterol biosynthesis with skeletal dysplasias; Cholesterol synthesis disorders; Cholesterol metabolism; Enterocyte cholesterol metabolism"	"RHOC GTPase cycle; RHOA GTPase cycle; RHOD GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; Regulation of MECP2 expression and activity; Initiation of Nuclear Envelope (NE) Reformation; Cholesterol biosynthesis"	"19"	"0"	"185.4"	"169.0"	"210.1"	"181.8"	"181.5"	"213.5"	"250.7"	"284.7"	"669.5"	"1118.0"	"1459.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62841"	"40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2"	"23"	"2"	"3"	"2"	"145"	"17.0"	"10.39"	"454.21"	"5.85"	"1"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00203"	"6209"	"ENSG00000115268"	"RPS15"	"A5D8V9; hsa:6209; P11174; P62841; Q3KRA1; Q9UDC2"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Response of EIF2AK4 (GCN2) to amino acid deficiency; SRP-dependent cotranslational protein targeting to membrane; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"133.5"	"107.8"	"133.5"	"97.9"	"121.6"	"139.5"	"138.9"	"158.0"	"177.3"	"191.7"	"280.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86U06"	"Probable RNA-binding protein 23 OS=Homo sapiens OX=9606 GN=RBM23 PE=1 SV=1"	"8"	"3"	"6"	"1"	"439"	"48.7"	"9.85"	"1075.07"	"5.85"	"3"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf15519"	"55147"	"ENSG00000100461"	"RBM23"	"D3DS32; hsa:55147; Q86U06; Q8ND16; Q8TB88; Q8WY40; Q9BUJ1; Q9NVV7"	""	""	"0"	"0"	"6.1"	"8.2"	"6.9"	"6.0"	"6.3"	"4.9"	"5.8"	"6.8"	"21.6"	"24.3"	"38.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60488"	"Long-chain-fatty-acid--CoA ligase 4 OS=Homo sapiens OX=9606 GN=ACSL4 PE=1 SV=2"	"3"	"2"	"3"	"1"	"711"	"79.1"	"8.38"	"313.01"	"5.85"	"1"	"2"	"other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00501"	"2182"	"ENSG00000068366"	"ACSL4"	"D3DUY2; hsa:2182; O60488; O60848; O60849; Q5JWV8"	"Fatty acid beta-oxidation; Fatty acid biosynthesis; Mitochondrial long chain fatty acid beta-oxidation; PPAR signaling pathway; Ferroptosis; Thermogenesis; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Omega-3 / omega-6 fatty acid synthesis; Omega-9 fatty acid synthesis; Fatty acid transporters; Mitochondrial fatty acid oxidation disorders"	"Synthesis of very long-chain fatty acyl-CoAs; Intracellular metabolism of fatty acids regulates insulin secretion"	"13"	"0"	"45.7"	"53.0"	"32.8"	"27.9"	"41.8"	"43.7"	"47.8"	"56.0"	"110.8"	"153.0"	"227.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q03188"	"Centromere protein C OS=Homo sapiens OX=9606 GN=CENPC PE=1 SV=2"	"2"	"2"	"4"	"2"	"943"	"106.8"	"9.39"	"619.45"	"5.85"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf11699, Pf15620, Pf15622"	"1060"	"ENSG00000145241"	"CENPC"	"hsa:1060; Q03188; Q6PIR0; Q8IW27; Q9P0M5"	""	"Separation of Sister Chromatids; Deposition of new CENPA-containing nucleosomes at the centromere; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"7"	"0"	"42.8"	"29.7"	"39.3"	"36.8"	"39.9"	"43.9"	"45.5"	"56.1"	"94.7"	"137.9"	"155.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61353"	"60S ribosomal protein L27 OS=Homo sapiens OX=9606 GN=RPL27 PE=1 SV=2"	"13"	"3"	"5"	"3"	"136"	"15.8"	"10.56"	"983.78"	"5.84"	"3"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00467, Pf01777"	"6155"	"ENSG00000131469"	"RPL27"	"hsa:6155; P08526; P61353; Q4G0A9"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; SRP-dependent cotranslational protein targeting to membrane; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"15"	"0"	"471.3"	"431.1"	"509.4"	"430.8"	"530.9"	"549.4"	"611.7"	"732.8"	"1116.4"	"2204.6"	"3586.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43678"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 OS=Homo sapiens OX=9606 GN=NDUFA2 PE=1 SV=3"	"21"	"1"	"1"	"1"	"99"	"10.9"	"9.57"	""	"5.84"	""	"1"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes"	"other membranes;mitochondrion"	"transporter activity"	"Pf05047"	"4695"	"ENSG00000131495"	"NDUFA2"	"D6RJD6; hsa:4695; O43678; Q6IAY8"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"27.0"	"15.6"	"22.0"	"22.8"	"25.0"	"22.6"	"29.1"	"37.7"	"174.1"	"224.6"	"280.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51452"	"Dual specificity protein phosphatase 3 OS=Homo sapiens OX=9606 GN=DUSP3 PE=1 SV=1"	"13"	"2"	"3"	"2"	"185"	"20.5"	"7.80"	"308.66"	"5.83"	"1"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00782"	"1845"	"ENSG00000108861"	"DUSP3"	"D3DX45; hsa:1845; P51452; Q5U0J1; Q8IYJ9"	"MAPK signaling pathway; Fragile X syndrome"	"ERKs are inactivated"	"3"	"0"	"28.8"	"29.2"	"32.4"	"26.3"	"37.1"	"30.4"	"33.8"	"48.9"	"91.7"	"165.6"	"303.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16512"	"Serine/threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2"	"3"	"2"	"3"	"2"	"942"	"103.9"	"6.37"	"377.61"	"5.83"	"1"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00433, Pf02185"	"5585"	"ENSG00000123143"	"PKN1"	"A8K7W5; B2R9R4; B3KVN3; hsa:5585; Q15143; Q16512; Q504U4; Q8IUV5; Q9UD44"	"Apoptosis-related network due to altered Notch3 in ovarian cancer; PI3K-Akt signaling pathway; IL-18 signaling pathway; G13 signaling pathway"	"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; RAC1 GTPase cycle; RHOC GTPase cycle; RHOA GTPase cycle; RHOB GTPase cycle"	"10"	"0"	"42.0"	"45.2"	"57.2"	"40.4"	"50.8"	"45.0"	"57.1"	"79.0"	"163.0"	"426.5"	"604.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75962"	"Triple functional domain protein OS=Homo sapiens OX=9606 GN=TRIO PE=1 SV=2"	"1"	"2"	"3"	"2"	"3097"	"346.7"	"6.37"	"300.75"	"5.82"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00018, Pf00069, Pf00169, Pf00435, Pf00621, Pf00650, Pf07679, Pf16609"	"7204"	"ENSG00000038382"	"TRIO"	"D3DTD1; hsa:7204; O75962; Q13458; Q59EQ7; Q6PJC9; Q6ZN05; Q8IWK8"	"Microtubule cytoskeleton regulation; Neural crest cell migration during development; Neural crest cell migration in cancer"	"RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; NRAGE signals death through JNK; G alpha (12/13) signalling events; RHOG GTPase cycle; G alpha (q) signalling events; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOJ GTPase cycle; DCC mediated attractive signaling"	"14"	"0"	"19.4"	"17.4"	"24.1"	"23.9"	"21.4"	"25.2"	"40.2"	"71.3"	"123.7"	"165.2"	"168.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z4Q2"	"HEAT repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=HEATR3 PE=1 SV=2"	"2"	"1"	"4"	"1"	"680"	"74.5"	"5.11"	"696.56"	"5.82"	"1"	"1"	"transport;other biological processes"	""	"other molecular function"	"Pf13513"	"55027"	"ENSG00000155393"	"HEATR3"	"A8K1N4; hsa:55027; Q7Z4Q2; Q8N525; Q8WV56; Q96CC9; Q9NWN7"	""	""	"0"	"0"	"10.4"	"4.7"	"5.5"	"8.2"	"6.5"	"4.1"	"8.2"	"12.2"	"53.7"	"134.7"	"215.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q68E01"	"Integrator complex subunit 3 OS=Homo sapiens OX=9606 GN=INTS3 PE=1 SV=1"	"3"	"1"	"1"	"1"	"1043"	"118.0"	"5.80"	""	"5.82"	""	"1"	"cell cycle OR cell proliferation;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	""	"Pf10189"	"65123"	"ENSG00000143624; ENSG00000262826"	"INTS3"	"A8K1W0; B4DQC8; B4E3U9; D3DV57; hsa:65123; Q4G0E5; Q5VUQ5; Q5VUQ6; Q5VUR0; Q5VUR1; Q68DJ1; Q68E01; Q69YR5; Q6AI57; Q6DKG7; Q6MZQ4; Q6MZZ9; Q8NC46; Q8TB23; Q9H6S9"	""	"RNA polymerase II transcribes snRNA genes"	"1"	"0"	"33.0"	"28.4"	"55.7"	"46.5"	"43.5"	"41.4"	"47.9"	"39.4"	"65.9"	"86.0"	"115.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94813"	"Slit homolog 2 protein OS=Homo sapiens OX=9606 GN=SLIT2 PE=1 SV=1"	"2"	"2"	"3"	"2"	"1529"	"169.8"	"7.06"	"1075.57"	"5.81"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;other membranes;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00008, Pf01462, Pf01463, Pf02210, Pf12661, Pf13855"	"9353"	"ENSG00000145147"	"SLIT2"	"A0A0A6YYB8; B7ZLR5; hsa:9353; O94813; O95710; Q17RU3; Q9Y5Q7"	"Spinal cord injury; Robo4 and VEGF signaling pathways crosstalk; Genes controlling nephrogenesis; GDNF/RET signaling axis; Development of ureteric collection system"	"Regulation of expression of SLITs and ROBOs; Netrin-1 signaling; Inactivation of CDC42 and RAC1; Activation of RAC1; Regulation of commissural axon pathfinding by SLIT and ROBO; Role of ABL in ROBO-SLIT signaling; SLIT2:ROBO1 increases RHOA activity"	"13"	"0"	"15.8"	"21.6"	"18.6"	"20.4"	"18.7"	"28.7"	"30.6"	"29.3"	"84.3"	"142.4"	"200.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96HC4"	"PDZ and LIM domain protein 5 OS=Homo sapiens OX=9606 GN=PDLIM5 PE=1 SV=5"	"3"	"1"	"2"	"1"	"596"	"63.9"	"8.21"	"633.42"	"5.80"	"1"	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412, Pf00595, Pf15936"	"10611"	"ENSG00000163110"	"PDLIM5"	"A8K6F9; D6RB78; E9PBF5; hsa:10611; O60705; Q56VN4; Q5UW38; Q8WVK0; Q96HC4"	"Extracellular vesicles in the crosstalk of cardiac cells"	"Neurexins and neuroligins"	"2"	"0"	"72.5"	"72.5"	"69.0"	"67.9"	"77.7"	"77.3"	"95.9"	"97.8"	"202.9"	"404.6"	"691.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P1N9"	"Putative deoxyribonuclease TATDN1 OS=Homo sapiens OX=9606 GN=TATDN1 PE=1 SV=2"	"9"	"2"	"4"	"2"	"297"	"33.6"	"6.96"	"559.05"	"5.80"	"2"	"2"	"DNA metabolism"	"nucleus"	"other molecular function"	"Pf01026"	"83940"	"ENSG00000147687"	"TATDN1"	"B2R5J0; hsa:83940; Q6P1N9; Q8TD02; Q9BY40"	""	""	"0"	"0"	"21.8"	"27.5"	"26.1"	"27.0"	"35.9"	"29.1"	"30.9"	"47.0"	"113.7"	"232.1"	"307.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49821"	"NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV1 PE=1 SV=4"	"4"	"2"	"4"	"2"	"464"	"50.8"	"8.21"	"526.15"	"5.79"	"2"	"2"	"other metabolic processes;transport"	"other membranes;cytosol;mitochondrion"	"transporter activity;other molecular function"	"Pf01512, Pf10531, Pf10589"	"4723"	"ENSG00000167792"	"NDUFV1"	"hsa:4723; O60924; O60940; P49821; Q16104; Q6IBR3; Q96BF8; Q96HS7"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"37.5"	"41.7"	"62.2"	"50.5"	"61.9"	"49.5"	"60.4"	"87.3"	"215.4"	"500.3"	"688.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P161"	"39S ribosomal protein L54, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL54 PE=1 SV=1"	"19"	"1"	"1"	"1"	"138"	"15.8"	"9.60"	""	"5.79"	""	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf08561"	"116541"	"ENSG00000183617"	"MRPL54"	"hsa:116541; Q6P161"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"57.8"	"56.1"	"54.7"	"53.4"	"57.9"	"56.8"	"69.2"	"81.4"	"112.9"	"153.4"	"236.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P289"	"Serine/threonine-protein kinase 26 OS=Homo sapiens OX=9606 GN=STK26 PE=1 SV=2"	"5"	"2"	"4"	"1"	"416"	"46.5"	"5.29"	"633.49"	"5.78"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"51765"	"ENSG00000134602"	"STK26"	"B2RAU2; hsa:51765; Q3ZB77; Q8NC04; Q9BXC3; Q9BXC4; Q9P289"	""	"Apoptotic cleavage of cellular proteins"	"1"	"1"	"107.2"	"89.7"	"116.1"	"96.0"	"107.8"	"107.4"	"118.3"	"149.3"	"254.2"	"639.1"	"1514.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N6R0"	"eEF1A lysine and N-terminal methyltransferase OS=Homo sapiens OX=9606 GN=EEF1AKNMT PE=1 SV=1"	"3"	"1"	"2"	"1"	"699"	"78.7"	"6.73"	""	"5.77"	""	"1"	"other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01564, Pf08241"	"51603"	"ENSG00000010165"	"METTL13"	"A6NFK0; A8K6S5; hsa:51603; O94940; Q53EZ6; Q5TGP9; Q5TGQ0; Q8N2P8; Q8N6R0; Q96J11; Q96SQ0; Q9Y2Z1; Q9Y3M6"	""	""	"0"	"0"	"39.3"	"29.6"	"44.8"	"43.0"	"44.9"	"41.1"	"50.9"	"86.4"	"240.0"	"443.2"	"690.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P2M7"	"Cingulin OS=Homo sapiens OX=9606 GN=CGN PE=1 SV=2"	"2"	"2"	"4"	"2"	"1197"	"136.3"	"5.54"	"649.62"	"5.76"	"2"	"2"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"62.8"	"62.7"	"89.1"	"79.0"	"85.0"	"90.0"	"95.7"	"106.1"	"146.2"	"226.0"	"349.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35998"	"26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3"	"7"	"4"	"6"	"4"	"433"	"48.6"	"5.95"	"1400.74"	"5.76"	"4"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf17862"	"5701"	"ENSG00000161057"	"PSMC2"	"A4D0Q1; B7Z5E2; hsa:5701; P35998; Q3LIA5; Q9UDI3"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"Neutrophil degranulation; ABC-family proteins mediated transport; Defective CFTR causes cystic fibrosis; UCH proteinases; Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; The role of GTSE1 in G2/M progression after G2 checkpoint; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; SCF(Skp2)-mediated degradation of p27/p21; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; MAPK6/MAPK4 signaling; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"64"	"0"	"134.2"	"130.0"	"149.7"	"118.9"	"116.5"	"122.2"	"170.0"	"197.7"	"259.2"	"396.0"	"965.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UQN3"	"Charged multivesicular body protein 2b OS=Homo sapiens OX=9606 GN=CHMP2B PE=1 SV=1"	"9"	"2"	"4"	"2"	"213"	"23.9"	"8.76"	"753.06"	"5.75"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf03357"	"25978"	"ENSG00000083937"	"CHMP2B"	"B4DJG8; hsa:25978; Q53HC7; Q9UQN3; Q9Y4U6"	""	"Budding and maturation of HIV virion; Endosomal Sorting Complex Required For Transport (ESCRT); Late endosomal microautophagy; HCMV Late Events; Sealing of the nuclear envelope (NE) by ESCRT-III; Macroautophagy; Pyroptosis; Translation of Replicase and Assembly of the Replication Transcription Complex; Translation of Replicase and Assembly of the Replication Transcription Complex"	"9"	"0"	"262.3"	"192.1"	"240.4"	"246.3"	"233.1"	"246.7"	"266.4"	"274.4"	"407.5"	"912.0"	"1123.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07711"	"Cathepsin L1 OS=Homo sapiens OX=9606 GN=CTSL PE=1 SV=2"	"6"	"2"	"4"	"1"	"333"	"37.5"	"5.45"	"675.18"	"5.74"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00112, Pf08246"	"1514"	"ENSG00000135047"	"CTSL"	"hsa:1514; P07711; Q6IAV1; Q96QJ0"	"Primary focal segmental glomerulosclerosis (FSGS); Ebola virus infection in host; Mitochondrial immune response to SARS-CoV-2"	"MHC class II antigen presentation; Collagen degradation; Assembly of collagen fibrils and other multimeric structures; Attachment and Entry; RUNX1 regulates transcription of genes involved in differentiation of keratinocytes; Attachment and Entry; Trafficking and processing of endosomal TLR; Endosomal/Vacuolar pathway"	"12"	"0"	"16.0"	"16.8"	"19.1"	"16.8"	"15.5"	"18.2"	"44.6"	"100.8"	"273.8"	"374.9"	"487.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94903"	"Pyridoxal phosphate homeostasis protein OS=Homo sapiens OX=9606 GN=PLPBP PE=1 SV=1"	"5"	"2"	"3"	"2"	"275"	"30.3"	"7.50"	"357.65"	"5.71"	"1"	"2"	""	"cytosol;other cell component"	"other molecular function"	"Pf01168"	"11212"	"ENSG00000147471"	"PLPBP"	"hsa:11212; O94903; Q6FI94"	""	""	"0"	"0"	"106.5"	"108.0"	"142.1"	"124.1"	"121.5"	"126.5"	"158.3"	"222.5"	"790.9"	"1671.0"	"1963.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14677"	"Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1"	"4"	"2"	"4"	"2"	"625"	"68.2"	"6.42"	"497.14"	"5.70"	"2"	"2"	"transport"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01417"	"9685"	"ENSG00000113282"	"CLINT1"	"B7Z6F8; D3DQJ6; hsa:9685; Q14677; Q8NAF1; Q96E05"	""	"Golgi Associated Vesicle Biogenesis"	"1"	"0"	"169.1"	"132.9"	"177.2"	"153.3"	"192.5"	"185.3"	"196.9"	"227.3"	"350.1"	"615.0"	"815.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86W34"	"Archaemetzincin-2 OS=Homo sapiens OX=9606 GN=AMZ2 PE=1 SV=2"	"6"	"2"	"4"	"1"	"360"	"41.2"	"8.15"	"722.72"	"5.69"	"2"	"2"	"protein metabolism"	""	"other molecular function"	"Pf07998"	"51321"	"ENSG00000196704"	"AMZ2"	"A6NLD9; B3KR44; hsa:51321; Q5XKF1; Q86W34; Q9NZE2"	""	""	"0"	"0"	"9.4"	"6.4"	"7.4"	"7.3"	"8.6"	"4.6"	"12.7"	"27.2"	"46.2"	"80.5"	"43.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01968"	"Inositol polyphosphate 5-phosphatase OCRL OS=Homo sapiens OX=9606 GN=OCRL PE=1 SV=3"	"3"	"3"	"4"	"2"	"901"	"104.1"	"6.55"	"529.59"	"5.67"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00620, Pf03372, Pf16726"	"4952"	"ENSG00000122126"	"OCRL"	"A6NKI1; A8KAP2; B7ZLX2; hsa:4952; O60800; Q01968; Q15684; Q15774; Q4VY09; Q4VY10; Q5JQF1; Q5JQF2; Q9UJG5; Q9UMA5"	"VEGFA-VEGFR2 signaling; Ciliopathies; Bardet-Biedl syndrome"	"Clathrin-mediated endocytosis; RAC3 GTPase cycle; RHOJ GTPase cycle; Golgi Associated Vesicle Biogenesis; Synthesis of PIPs at the plasma membrane; Synthesis of PIPs at the Golgi membrane; Synthesis of IP2, IP, and Ins in the cytosol; Synthesis of IP3 and IP4 in the cytosol"	"11"	"0"	"19.2"	"25.3"	"28.2"	"17.2"	"30.6"	"24.4"	"37.7"	"47.4"	"115.7"	"212.8"	"245.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15599"	"Na(+)/H(+) exchange regulatory cofactor NHE-RF2 OS=Homo sapiens OX=9606 GN=SLC9A3R2 PE=1 SV=2"	"4"	"1"	"2"	"1"	"337"	"37.4"	"7.93"	"645.10"	"5.67"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00595, Pf09007"	"9351"	"ENSG00000065054"	"NHERF2"	"D3DU84; D3DU85; H3BSV6; hsa:9351; O00272; O00556; Q15599; Q3KQY7"	""	""	"0"	"0"	"36.9"	"39.9"	"36.6"	"30.6"	"36.2"	"43.4"	"47.7"	"40.8"	"44.4"	"61.4"	"61.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TDD1"	"ATP-dependent RNA helicase DDX54 OS=Homo sapiens OX=9606 GN=DDX54 PE=1 SV=2"	"2"	"2"	"3"	"1"	"881"	"98.5"	"10.02"	"505.05"	"5.65"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"ER/Golgi;nucleus"	"signal transduction activity or receptor binding;other molecular function"	"Pf00270, Pf00271, Pf08147"	"79039"	"ENSG00000123064"	"DDX54"	"hsa:79039; Q86YT8; Q8TDD1; Q9BRZ1"	""	""	"0"	"1"	"44.8"	"31.9"	"47.6"	"34.1"	"37.5"	"42.0"	"54.4"	"54.3"	"87.4"	"161.0"	"280.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13667"	"Protein disulfide-isomerase A4 OS=Homo sapiens OX=9606 GN=PDIA4 PE=1 SV=2"	"6"	"4"	"6"	"4"	"645"	"72.9"	"5.07"	"1256.18"	"5.64"	"4"	"2"	"protein metabolism;other metabolic processes;stress response;transport"	"non-structural extracellular;ER/Golgi;other cell component"	"other molecular function"	"Pf00085, Pf13848"	"9601"	"ENSG00000155660"	"PDIA4"	"A8K4K6; hsa:9601; P13667; Q549T6"	""	""	"0"	"0"	"792.4"	"792.8"	"802.4"	"717.4"	"777.5"	"822.0"	"938.9"	"1110.5"	"1079.1"	"1254.9"	"1720.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49916"	"DNA ligase 3 OS=Homo sapiens OX=9606 GN=LIG3 PE=1 SV=2"	"2"	"2"	"4"	"2"	"1009"	"112.8"	"9.01"	"602.66"	"5.63"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00645, Pf01068, Pf04675, Pf04679, Pf16759"	"3980"	"ENSG00000005156"	"LIG3"	"E5KLB5; E5KLB6; hsa:3980; P49916; Q16714; Q6NVK3"	"Base excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; 17q12 copy number variation syndrome"	"HDR through MMEJ (alt-NHEJ); Gap-filling DNA repair synthesis and ligation in TC-NER; Gap-filling DNA repair synthesis and ligation in GG-NER; APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway; Resolution of AP sites via the single-nucleotide replacement pathway"	"9"	"0"	"110.6"	"106.8"	"116.3"	"98.9"	"113.4"	"99.6"	"136.5"	"185.2"	"413.6"	"868.8"	"1764.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14527"	"Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2"	"3"	"2"	"4"	"2"	"1009"	"113.9"	"8.60"	"639.18"	"5.63"	"2"	"2"	"cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf08797, Pf13923"	"6596"	"ENSG00000071794"	"HLTF"	"D3DNH3; hsa:6596; Q14527; Q14536; Q16051; Q7KYJ6; Q86YA5; Q92652; Q96KM9"	"Retinoblastoma gene in cancer"	"E3 ubiquitin ligases ubiquitinate target proteins"	"2"	"0"	"27.7"	"16.5"	"27.4"	"28.4"	"39.0"	"23.9"	"33.4"	"40.1"	"49.3"	"81.3"	"173.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15369"	"Elongin-C OS=Homo sapiens OX=9606 GN=ELOC PE=1 SV=1"	"18"	"1"	"2"	"1"	"112"	"12.5"	"4.78"	"485.34"	"5.60"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf03931"	"6921"	"ENSG00000154582"	"ELOC"	"E5RGD9; hsa:6921; Q15369; Q567Q6"	"Dual hijack model of Vif in HIV infection; VEGFA-VEGFR2 signaling; Type 2 papillary renal cell carcinoma; Hijack of ubiquitination by SARS-CoV-2"	"Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; Regulation of expression of SLITs and ROBOs; Antigen processing: Ubiquitination & Proteasome degradation; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Vif-mediated degradation of APOBEC3G; Neddylation; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; Inactivation of CSF3 (G-CSF) signaling"	"21"	"0"	"14.1"	"13.6"	"18.7"	"13.6"	"9.5"	"19.4"	"21.7"	"24.6"	"54.6"	"109.5"	"144.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BXC9"	"Bardet-Biedl syndrome 2 protein OS=Homo sapiens OX=9606 GN=BBS2 PE=1 SV=1"	"1"	"1"	"4"	"1"	"721"	"79.8"	"6.15"	"699.54"	"5.59"	"1"	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"31.4"	"36.6"	"36.2"	"36.0"	"42.7"	"51.3"	"50.3"	"94.6"	"239.1"	"513.7"	"632.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62917"	"60S ribosomal protein L8 OS=Homo sapiens OX=9606 GN=RPL8 PE=1 SV=2"	"7"	"2"	"4"	"2"	"257"	"28.0"	"11.03"	"653.38"	"5.58"	"2"	"2"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00181, Pf03947"	"6132"	"ENSG00000161016"	"RPL8"	"A8K094; D3DWN2; hsa:6132; P25120; P62917; Q567Q7; Q969V7; Q9BWQ9"	"Cytoplasmic ribosomal proteins"	"Major pathway of rRNA processing in the nucleolus and cytosol; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"281.5"	"278.2"	"263.9"	"225.8"	"248.9"	"298.5"	"359.3"	"465.9"	"739.3"	"1375.3"	"2125.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6Y7W6"	"GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1299"	"150.0"	"5.54"	"564.43"	"5.57"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf02213"	"26058"	"ENSG00000204120"	"GIGYF2"	"A6H8W4; B9EG55; E9PBB0; hsa:26058; O75137; Q6Y7W6; Q7Z2Z8; Q7Z3I2; Q96HU4; Q9NV82"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"77.3"	"72.7"	"79.6"	"76.3"	"78.6"	"84.3"	"88.7"	"81.5"	"108.9"	"162.1"	"229.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43257"	"Zinc finger HIT domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ZNHIT1 PE=1 SV=1"	"8"	"1"	"2"	"1"	"154"	"17.5"	"9.41"	"527.02"	"5.57"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf04438"	"10467"	"ENSG00000106400"	"ZNHIT1"	"hsa:10467; O43257; Q6IB12"	""	""	"0"	"0"	"39.3"	"36.8"	"39.2"	"42.0"	"45.0"	"43.9"	"47.1"	"73.3"	"183.3"	"598.5"	"765.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P45880"	"Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2"	"6"	"2"	"3"	"2"	"294"	"31.5"	"7.56"	"264.48"	"5.56"	"1"	"2"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"other membranes;cytoskeleton;mitochondrion;other cell component"	"transporter activity;other molecular function"	"Pf01459"	"7417"	"ENSG00000165637"	"VDAC2"	"hsa:7417; P45880; Q5VWK1; Q5VWK3; Q6IB40; Q7L3J5; Q9BWK8; Q9Y5I6"	"Alzheimer's disease and miRNA effects; Ferroptosis; Alzheimer's disease"	"Ub-specific processing proteases; Mitochondrial calcium ion transport"	"5"	"0"	"57.8"	"59.5"	"70.7"	"60.6"	"53.6"	"52.8"	"68.6"	"108.9"	"285.7"	"760.2"	"1067.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51003"	"Poly(A) polymerase alpha OS=Homo sapiens OX=9606 GN=PAPOLA PE=1 SV=4"	"5"	"3"	"4"	"3"	"745"	"82.8"	"7.37"	"538.79"	"5.56"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01909, Pf04926, Pf04928"	"10914"	"ENSG00000090060"	"PAPOLA"	"hsa:10914; P51003; Q86SX4; Q86TV0; Q8IYF5; Q9BVU2"	"mRNA processing"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"5"	"0"	"29.6"	"23.1"	"39.0"	"35.2"	"33.8"	"35.6"	"39.6"	"71.0"	"232.7"	"533.1"	"686.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43432"	"Eukaryotic translation initiation factor 4 gamma 3 OS=Homo sapiens OX=9606 GN=EIF4G3 PE=1 SV=2"	"1"	"2"	"4"	"1"	"1585"	"176.5"	"5.38"	"698.43"	"5.56"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf02020, Pf02847, Pf02854"	"8672"	"ENSG00000075151"	"EIF4G3"	"B9EGQ7; hsa:8672; O43432; Q15597; Q504Z1; Q5SWC3; Q8NEN1"	"Translation factors; Translation inhibitors in chronically activated PDGFRA cells"	"ISG15 antiviral mechanism"	"3"	"0"	"17.5"	"9.2"	"12.7"	"16.4"	"18.5"	"15.2"	"18.3"	"21.7"	"59.1"	"149.5"	"181.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50750"	"Cyclin-dependent kinase 9 OS=Homo sapiens OX=9606 GN=CDK9 PE=1 SV=3"	"5"	"2"	"3"	"1"	"372"	"42.8"	"8.79"	"348.80"	"5.54"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00069"	"1025"	"ENSG00000136807"	"CDK9"	"hsa:1025; P50750; Q5JU24; Q5JU25; Q5U006; Q96TF1"	"MicroRNAs in cardiomyocyte hypertrophy; IL-9 signaling pathway; Cardiac hypertrophic response; Initiation of transcription and translation elongation at the HIV-1 LTR; Male infertility"	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; Estrogen-dependent gene expression; Interactions of Tat with host cellular proteins"	"20"	"0"	"45.8"	"30.5"	"41.7"	"38.6"	"46.3"	"39.4"	"52.1"	"61.1"	"102.0"	"140.3"	"168.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P18074"	"General transcription and DNA repair factor IIH helicase subunit XPD OS=Homo sapiens OX=9606 GN=ERCC2 PE=1 SV=1"	"4"	"2"	"4"	"2"	"760"	"86.9"	"7.15"	"541.05"	"5.54"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06733, Pf06777, Pf13307"	"2068"	"ENSG00000104884"	"ERCC2"	"hsa:2068; P18074; Q2TB78; Q2YDY2; Q7KZU6; Q8N721"	"Fluoropyrimidine activity; Eukaryotic transcription initiation; Male infertility; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; Cytosolic iron-sulfur cluster assembly; Formation of Incision Complex in GG-NER; Dual Incision in GG-NER"	"36"	"0"	"15.6"	"16.7"	"20.4"	"26.1"	"27.0"	"21.2"	"29.9"	"32.6"	"76.8"	"153.9"	"187.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HBM6"	"Transcription initiation factor TFIID subunit 9B OS=Homo sapiens OX=9606 GN=TAF9B PE=1 SV=1"	"12"	"2"	"3"	"2"	"251"	"27.6"	"9.55"	"425.79"	"5.54"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf02291"	"51616"	"ENSG00000187325"	"TAF9B"	"B2RUZ9; hsa:51616; Q9HBM6; Q9Y2S3"	""	"Ub-specific processing proteases; RNA Polymerase II Pre-transcription Events; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Regulation of TP53 Activity through Phosphorylation"	"10"	"0"	"15.9"	"17.5"	"21.5"	"18.6"	"16.2"	"17.4"	"17.0"	"24.7"	"47.1"	"104.0"	"135.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14727"	"Apoptotic protease-activating factor 1 OS=Homo sapiens OX=9606 GN=APAF1 PE=1 SV=2"	"1"	"1"	"4"	"1"	"1248"	"141.7"	"6.40"	"703.05"	"5.53"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00400, Pf00619, Pf00931, Pf17908"	"317"	"ENSG00000120868"	"APAF1"	"B2RMX8; hsa:317; O14727; O43297; Q7Z438; Q9BXZ6; Q9UBZ5; Q9UGN8; Q9UGN9; Q9UGP0; Q9UJ58; Q9UJ59; Q9UJ60; Q9UJ61; Q9UJ62; Q9UJ63; Q9UJ64; Q9UJ65; Q9UJ66; Q9UJ67; Q9UNC9"	"miRNA regulation of DNA damage response; Alzheimer's disease and miRNA effects; TNF-alpha signaling pathway; Parkinson's disease pathway; Amyotrophic lateral sclerosis (ALS); Nanomaterial induced apoptosis; Apoptosis; Fas ligand pathway and stress induction of heat shock proteins; Apoptosis modulation by HSP70; Oxidative damage response; miRNA regulation of p53 pathway in prostate cancer; Measles virus infection; Small cell lung cancer; Hepatitis B infection; Regucalcin in proximal tubule epithelial kidney cells; Host-pathogen interaction of human coronaviruses - apoptosis; p53 transcriptional gene network; Complement system in neuronal development and plasticity; Alzheimer's disease; CKAP4 signaling pathway map; DNA damage response"	"Neutrophil degranulation; Transcriptional Regulation by E2F6; Activation of caspases through apoptosome-mediated cleavage; SMAC (DIABLO) binds to IAPs ; SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes ; TP53 Regulates Transcription of Caspase Activators and Caspases; Regulation of the apoptosome activity"	"29"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"1.4"	"17.7"	"49.8"	"70.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2U8"	"Inner nuclear membrane protein Man1 OS=Homo sapiens OX=9606 GN=LEMD3 PE=1 SV=2"	"2"	"1"	"2"	"1"	"911"	"99.9"	"7.55"	"615.16"	"5.53"	"1"	"1"	"other biological processes"	"other membranes;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03020, Pf09402"	"23592"	"ENSG00000174106"	"LEMD3"	"hsa:23592; Q9NT47; Q9NYA5; Q9Y2U8"	"Envelope proteins and their potential roles in EDMD physiopathology"	"RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RND2 GTPase cycle; RHOG GTPase cycle; RHOD GTPase cycle; RND3 GTPase cycle; RND1 GTPase cycle; Initiation of Nuclear Envelope (NE) Reformation; Depolymerization of the Nuclear Lamina"	"12"	"0"	"47.7"	"59.4"	"35.6"	"46.0"	"35.3"	"45.2"	"66.0"	"95.4"	"215.8"	"421.7"	"542.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NW08"	"DNA-directed RNA polymerase III subunit RPC2 OS=Homo sapiens OX=9606 GN=POLR3B PE=1 SV=2"	"2"	"2"	"3"	"2"	"1133"	"127.7"	"8.50"	"278.32"	"5.52"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00562, Pf04560, Pf04561, Pf04563, Pf04565, Pf04566, Pf04567"	"55703"	"ENSG00000013503"	"POLR3B"	"A8K6H0; B3KV73; F5H1E6; hsa:55703; Q9NW08; Q9NW59"	"Pyrimidine metabolism; Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation"	"10"	"0"	"17.1"	"19.9"	"17.1"	"10.6"	"12.8"	"11.9"	"17.9"	"26.3"	"49.0"	"93.4"	"193.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96DH6"	"RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1"	"6"	"1"	"1"	"1"	"328"	"35.2"	"8.48"	""	"5.52"	""	"1"	"developmental processes;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"124540"	"ENSG00000153944"	"MSI2"	"hsa:124540; Q7Z6M7; Q8N9T4; Q96DH6"	""	"RHOBTB2 GTPase cycle"	"1"	"0"	"97.5"	"120.8"	"96.3"	"106.7"	"106.7"	"87.4"	"143.3"	"197.7"	"205.0"	"292.0"	"399.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96CP2"	"FLYWCH family member 2 OS=Homo sapiens OX=9606 GN=FLYWCH2 PE=1 SV=1"	"6"	"1"	"4"	"1"	"140"	"14.6"	"8.46"	"743.68"	"5.52"	"1"	"1"	""	""	""	"Pf15423"	"114984"	"ENSG00000162076"	"FLYWCH2"	"hsa:114984; Q96CP2"	""	""	"0"	"0"	"125.1"	"126.4"	"133.5"	"111.1"	"133.5"	"135.0"	"161.2"	"291.0"	"903.4"	"1320.1"	"1642.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q68CZ6"	"HAUS augmin-like complex subunit 3 OS=Homo sapiens OX=9606 GN=HAUS3 PE=1 SV=1"	"3"	"2"	"4"	"2"	"603"	"69.6"	"5.55"	"516.40"	"5.52"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton"	""	"Pf14932"	"79441"	"ENSG00000214367"	"HAUS3"	"B4DF64; hsa:79441; O43606; Q68CZ6; Q8TAZ5; Q9BTJ9"	""	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"7"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75312"	"Zinc finger protein ZPR1 OS=Homo sapiens OX=9606 GN=ZPR1 PE=1 SV=1"	"6"	"2"	"4"	"2"	"459"	"50.9"	"4.73"	"642.35"	"5.52"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf03367"	"8882"	"ENSG00000109917"	"ZPR1"	"hsa:8882; O75312; Q2TAA0"	""	""	"0"	"0"	"75.4"	"64.1"	"78.8"	"66.4"	"76.1"	"74.8"	"85.5"	"98.1"	"161.4"	"259.4"	"464.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23470"	"Receptor-type tyrosine-protein phosphatase gamma OS=Homo sapiens OX=9606 GN=PTPRG PE=1 SV=4"	"2"	"2"	"2"	"2"	"1445"	"161.9"	"6.42"	""	"5.52"	""	"2"	"protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes"	"other molecular function"	"Pf00041, Pf00102, Pf00194"	"5793"	"ENSG00000144724"	"PTPRG"	"B2RU12; B7ZLX5; hsa:5793; P23470; Q15623; Q59EE0; Q68DU5"	""	""	"0"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"2.0"	"0.0"	"0.0"	"5.2"	"14.1"	"47.8"	"102.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96IZ7"	"Serine/Arginine-related protein 53 OS=Homo sapiens OX=9606 GN=RSRC1 PE=1 SV=1"	"6"	"2"	"4"	"2"	"334"	"38.7"	"11.08"	"595.87"	"5.51"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	""	""	"51319"	"ENSG00000174891"	"RSRC1"	"A8K2R9; hsa:51319; Q96IZ7; Q96QK2; Q9NZE5"	""	""	"0"	"0"	"136.3"	"101.8"	"128.1"	"140.4"	"134.5"	"149.2"	"147.6"	"154.5"	"244.8"	"424.6"	"708.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HCG8"	"Pre-mRNA-splicing factor CWC22 homolog OS=Homo sapiens OX=9606 GN=CWC22 PE=1 SV=3"	"3"	"2"	"3"	"2"	"908"	"105.4"	"7.03"	"886.92"	"5.50"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity"	"Pf02847"	"57703"	"ENSG00000163510"	"CWC22"	"hsa:57703; Q05DC2; Q4G135; Q52LF0; Q6PEX2; Q7Z6I0; Q9H5L3; Q9H6Q6; Q9HCG8"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"35.4"	"27.7"	"53.0"	"34.8"	"41.0"	"47.4"	"58.9"	"69.4"	"141.7"	"317.6"	"691.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60002"	"Transcription elongation factor 1 homolog OS=Homo sapiens OX=9606 GN=ELOF1 PE=1 SV=1"	"22"	"1"	"1"	"1"	"83"	"9.5"	"8.00"	""	"5.50"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf05129"	"84337"	"ENSG00000130165"	"ELOF1"	"hsa:84337; P60002; Q8R1J7; Q96II4"	""	""	"0"	"0"	"51.9"	"44.6"	"58.2"	"55.7"	"60.7"	"58.3"	"75.2"	"131.1"	"345.0"	"316.3"	"200.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P83876"	"Thioredoxin-like protein 4A OS=Homo sapiens OX=9606 GN=TXNL4A PE=1 SV=1"	"14"	"1"	"2"	"1"	"142"	"16.8"	"5.85"	"697.06"	"5.49"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;cytosol;nucleus"	""	"Pf02966"	"10907"	"ENSG00000141759"	"TXNL4A"	"B2RC18; hsa:10907; O14834; P83876"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"3"	"0"	"54.4"	"58.3"	"57.0"	"53.6"	"54.9"	"52.2"	"67.1"	"68.9"	"73.9"	"124.4"	"227.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5M775"	"Cytospin-B OS=Homo sapiens OX=9606 GN=SPECC1 PE=1 SV=1"	"2"	"1"	"2"	"1"	"1068"	"118.5"	"6.70"	"673.90"	"5.48"	"1"	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	""	"Pf00307"	"92521"	"ENSG00000128487"	"SPECC1"	"B4DHH0; B7WNS8; hsa:92521; Q5IBP1; Q5IBP2; Q5IBP3; Q5IBP4; Q5M772; Q5M773; Q5M774; Q5M775; Q86XT8; Q8N4U4; Q8WU84; Q9HCQ3"	""	""	"0"	"0"	"42.4"	"33.9"	"44.5"	"37.0"	"42.3"	"38.2"	"51.3"	"47.5"	"64.3"	"103.7"	"150.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HC35"	"Echinoderm microtubule-associated protein-like 4 OS=Homo sapiens OX=9606 GN=EML4 PE=1 SV=3"	"1"	"2"	"4"	"2"	"981"	"108.8"	"6.40"	"634.31"	"5.48"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400, Pf03451, Pf07714"	"27436"	"ENSG00000143924"	"EML4"	"A6H8Y6; A6P4T4; A6P4V4; B2RBK3; B2RTW7; B5MCW9; hsa:27436; Q3SWW0; Q53R29; Q53TW8; Q6PJ45; Q9HC35; Q9NV40"	"Non-small cell lung cancer"	"EML4 and NUDC in mitotic spindle formation; ALK mutants bind TKIs; Nuclear events stimulated by ALK signaling in cancer"	"5"	"0"	"115.2"	"110.4"	"123.1"	"98.4"	"141.0"	"172.9"	"155.6"	"167.3"	"320.8"	"1027.0"	"1446.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22681"	"E3 ubiquitin-protein ligase CBL OS=Homo sapiens OX=9606 GN=CBL PE=1 SV=2"	"2"	"1"	"1"	"1"	"906"	"99.6"	"6.54"	""	"5.48"	""	"1"	"protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00627, Pf02262, Pf02761, Pf02762, Pf14447"	"867"	"ENSG00000110395"	"CBL"	"A3KMP8; hsa:867; P22681"	"RANKL/RANK signaling pathway; Prolactin signaling pathway; Glioblastoma signaling pathways; B cell receptor signaling pathway; IL-3 signaling pathway; Kit receptor signaling pathway; Physico-chemical features and toxicity-associated pathways; T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; IL-4 signaling pathway; EGF/EGFR signaling pathway; Insulin signaling; IL-2 signaling pathway; 4p16.3 copy number variation; Interferon type I signaling pathways; ErbB signaling pathway; T-cell receptor signaling pathway"	"Signaling by CSF1 (M-CSF) in myeloid cells; Regulation of signaling by CBL; Regulation of KIT signaling; Negative regulation of FLT3; Cargo recognition for clathrin-mediated endocytosis; Interleukin-6 signaling; EGFR downregulation; Negative regulation of MET activity; InlB-mediated entry of Listeria monocytogenes into host cell; Spry regulation of FGF signaling; TGF-beta receptor signaling activates SMADs; Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; Constitutive Signaling by EGFRvIII; PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1; FLT3 signaling by CBL mutants"	"38"	"0"	"14.7"	"13.2"	"15.3"	"13.7"	"16.7"	"15.9"	"20.5"	"32.5"	"57.3"	"115.1"	"146.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z5K2"	"Wings apart-like protein homolog OS=Homo sapiens OX=9606 GN=WAPL PE=1 SV=1"	"3"	"3"	"4"	"3"	"1190"	"132.9"	"5.44"	"592.38"	"5.47"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf07814"	"23063"	"ENSG00000062650"	"WAPL"	"A7E2B5; hsa:23063; Q5VSK5; Q7Z5K2; Q8IX10; Q92549"	"Cohesin complex - Cornelia de Lange syndrome; 10q22q23 copy number variation"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"6"	"0"	"89.0"	"70.4"	"88.3"	"75.1"	"88.8"	"93.3"	"99.7"	"104.4"	"168.3"	"298.8"	"470.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61024"	"Cyclin-dependent kinases regulatory subunit 1 OS=Homo sapiens OX=9606 GN=CKS1B PE=1 SV=1"	"20"	"1"	"2"	"1"	"79"	"9.7"	"8.94"	"563.54"	"5.47"	"1"	"1"	"cell cycle OR cell proliferation;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf01111"	"1163"	"ENSG00000173207"	"CKS1B"	"hsa:1163; P33551; P61024"	"Small cell lung cancer"	"SCF(Skp2)-mediated degradation of p27/p21; Cyclin D associated events in G1"	"3"	"0"	"74.0"	"110.6"	"48.2"	"41.4"	"52.6"	"72.0"	"109.8"	"168.8"	"319.5"	"900.1"	"1774.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z460"	"CLIP-associating protein 1 OS=Homo sapiens OX=9606 GN=CLASP1 PE=1 SV=1"	"2"	"2"	"3"	"1"	"1538"	"169.3"	"9.03"	"330.89"	"5.45"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02985, Pf12348"	"23332"	"ENSG00000074054"	"CLASP1"	"A2RU21; B7ZLX3; F5GWS0; hsa:23332; O75118; Q2KHQ9; Q5H9P0; Q7Z460; Q8N5B8; Q9BQT5"	"Microtubule cytoskeleton regulation; Splicing factor NOVA regulated synaptic proteins; 7q11.23 copy number variation syndrome"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Recruitment of NuMA to mitotic centrosomes; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Role of ABL in ROBO-SLIT signaling"	"17"	"0"	"4.1"	"16.5"	"2.6"	"2.7"	"7.9"	"5.3"	"8.0"	"8.4"	"7.3"	"29.1"	"45.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60911"	"Cathepsin L2 OS=Homo sapiens OX=9606 GN=CTSV PE=1 SV=2"	"6"	"2"	"4"	"1"	"334"	"37.3"	"8.76"	"714.87"	"5.45"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;other cytoplasmic organelle"	"enzyme regulator activity;other molecular function"	"Pf00112, Pf08246"	"1515"	"ENSG00000136943"	"CTSV"	"hsa:1515; O60233; O60911; Q2TB86; Q5T1U0"	"Endochondral ossification; Endochondral ossification with skeletal dysplasias; Pancreatic cancer subtypes"	"MHC class II antigen presentation; Assembly of collagen fibrils and other multimeric structures; RUNX1 regulates transcription of genes involved in differentiation of keratinocytes; Trafficking and processing of endosomal TLR; Endosomal/Vacuolar pathway; Activation of Matrix Metalloproteinases"	"10"	"1"	"82.8"	"74.1"	"92.1"	"87.0"	"77.8"	"81.5"	"139.6"	"372.7"	"804.1"	"1543.9"	"2103.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q02447"	"Transcription factor Sp3 OS=Homo sapiens OX=9606 GN=SP3 PE=1 SV=3"	"2"	"1"	"2"	"1"	"781"	"81.9"	"5.26"	"572.39"	"5.43"	"1"	"1"	"developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00096"	"6670"	"ENSG00000172845"	"SP3"	"A0AVL9; B4E2B7; hsa:6670; Q02447; Q69B26; Q69B27; Q8TD56; Q8WWU4; Q9BQR1"	"MECP2 and associated Rett syndrome; Non-genomic actions of 1,25 dihydroxyvitamin D3; Sudden infant death syndrome (SIDS) susceptibility pathways"	"SUMOylation of transcription factors"	"4"	"0"	"85.0"	"76.1"	"87.6"	"86.9"	"94.8"	"87.2"	"98.5"	"108.6"	"130.0"	"154.3"	"198.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52435"	"DNA-directed RNA polymerase II subunit RPB11-a OS=Homo sapiens OX=9606 GN=POLR2J PE=1 SV=1"	"18"	"1"	"1"	"1"	"117"	"13.3"	"5.86"	""	"5.43"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf13656"	"5439"	"ENSG00000005075"	"POLR2J"	"A5D6V8; hsa:5439; O43375; P52435"	"Pyrimidine metabolism; Eukaryotic transcription initiation"	"Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; mRNA Splicing - Major Pathway; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"43"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NW13"	"RNA-binding protein 28 OS=Homo sapiens OX=9606 GN=RBM28 PE=1 SV=3"	"3"	"2"	"4"	"2"	"759"	"85.7"	"9.22"	"604.85"	"5.41"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf00076"	"55131"	"ENSG00000106344"	"RBM28"	"A4D100; B4DU52; E9PDD9; hsa:55131; Q53H65; Q96CV3; Q9NW13"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"137.3"	"109.4"	"146.8"	"129.8"	"153.3"	"121.8"	"168.6"	"183.5"	"301.0"	"494.3"	"631.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P28074"	"Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3"	"5"	"1"	"2"	"1"	"263"	"28.5"	"6.92"	"596.69"	"5.40"	"1"	"1"	"protein metabolism;other metabolic processes;stress response"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00227"	"5693"	"ENSG00000100804"	"PSMB5"	"B2R4N9; B4DUM9; D3DS43; E9PAV2; hsa:5693; P28074; Q16242; Q6PEW2; Q7Z3B5; Q86T01; Q9TNN9"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Regulation of expression of SLITs and ROBOs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"62"	"0"	"3.4"	"3.0"	"3.2"	"2.8"	"4.7"	"5.3"	"3.7"	"7.6"	"10.1"	"36.1"	"113.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P2K8"	"eIF-2-alpha kinase GCN2 OS=Homo sapiens OX=9606 GN=EIF2AK4 PE=1 SV=3"	"1"	"2"	"3"	"2"	"1649"	"186.8"	"6.28"	"258.40"	"5.40"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00069, Pf05773, Pf12745, Pf13393"	"440275"	"ENSG00000128829"	"EIF2AK4"	"C9JEC4; hsa:440275; Q69YL7; Q6DC97; Q96GN6; Q9H5K1; Q9NSQ3; Q9NSZ5; Q9P2K8; Q9UJ56"	"Measles virus infection"	"Response of EIF2AK4 (GCN2) to amino acid deficiency"	"2"	"0"	"23.4"	"28.9"	"34.2"	"28.1"	"32.1"	"22.0"	"38.4"	"54.5"	"130.9"	"349.8"	"544.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NCN4"	"E3 ubiquitin-protein ligase RNF169 OS=Homo sapiens OX=9606 GN=RNF169 PE=1 SV=2"	"3"	"2"	"4"	"2"	"708"	"77.1"	"9.10"	"711.80"	"5.39"	"2"	"2"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf13920"	"254225"	"ENSG00000166439"	"RNF169"	"hsa:254225; Q6N015; Q8NCN4"	""	""	"0"	"0"	"101.7"	"77.1"	"108.7"	"94.7"	"93.6"	"98.4"	"120.9"	"101.1"	"171.0"	"254.3"	"286.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96A00"	"Protein phosphatase 1 regulatory subunit 14A OS=Homo sapiens OX=9606 GN=PPP1R14A PE=1 SV=1"	"11"	"1"	"2"	"1"	"147"	"16.7"	"9.38"	"692.83"	"5.37"	"1"	"1"	"other biological processes"	"cytosol"	"enzyme regulator activity"	"Pf05361"	"94274"	"ENSG00000167641"	"PPP1R14A"	"hsa:94274; Q7Z4X7; Q96A00; Q96S54"	"Hippo-Merlin signaling dysregulation; Airway smooth muscle cell contraction"	"RHO GTPases activate PKNs"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9GZZ1"	"N-alpha-acetyltransferase 50 OS=Homo sapiens OX=9606 GN=NAA50 PE=1 SV=1"	"8"	"1"	"2"	"1"	"169"	"19.4"	"8.81"	"492.98"	"5.36"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00583"	"80218"	"ENSG00000121579"	"NAA50"	"D3DN74; hsa:80218; Q68DQ1; Q9GZZ1"	"Metapathway biotransformation Phase I and II"	""	"1"	"0"	"8.1"	"10.6"	"14.0"	"10.0"	"9.3"	"10.6"	"7.9"	"21.6"	"92.0"	"324.9"	"381.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35250"	"Replication factor C subunit 2 OS=Homo sapiens OX=9606 GN=RFC2 PE=1 SV=3"	"6"	"1"	"2"	"1"	"354"	"39.1"	"6.44"	"560.40"	"5.36"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00004, Pf08542"	"5982"	"ENSG00000049541"	"RFC2"	"B5BU07; D3DXG3; hsa:5982; P32846; P35250; Q9BU93"	"DNA replication; Nucleotide excision repair; 7q11.23 copy number variation syndrome; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; HDR through Homologous Recombination (HRR); HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Activation of ATR in response to replication stress; Termination of translesion DNA synthesis; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Polymerase switching on the C-strand of the telomere; Polymerase switching; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER"	"27"	"0"	"32.2"	"40.8"	"46.4"	"38.8"	"47.1"	"43.3"	"50.0"	"75.4"	"128.1"	"203.1"	"253.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P158"	"Putative ATP-dependent RNA helicase DHX57 OS=Homo sapiens OX=9606 GN=DHX57 PE=1 SV=2"	"2"	"2"	"3"	"2"	"1386"	"155.5"	"7.71"	"390.70"	"5.35"	"1"	"2"	""	""	"other molecular function"	"Pf00270, Pf00271, Pf04408, Pf05773, Pf07717, Pf18044"	"90957"	"ENSG00000163214"	"DHX57"	"A2RRC7; hsa:90957; Q53SI4; Q6P158; Q6P9G1; Q7Z6H3; Q8NG17; Q96M33"	""	""	"0"	"0"	"26.8"	"28.4"	"30.9"	"30.4"	"33.8"	"22.2"	"43.1"	"47.5"	"116.8"	"260.7"	"374.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6KC79"	"Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2"	"1"	"4"	"6"	"4"	"2804"	"315.9"	"7.91"	"1265.56"	"5.34"	"4"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf12765, Pf12830"	"25836"	"ENSG00000164190"	"NIPBL"	"hsa:25836; Q6KC79; Q6KCD6; Q6N080; Q6ZT92; Q7Z2E6; Q8N4M5; Q9Y6Y3; Q9Y6Y4"	"Cohesin complex - Cornelia de Lange syndrome; NIPBL role in DNA damage - Cornelia de Lange syndrome"	"Cohesin Loading onto Chromatin"	"3"	"0"	"175.9"	"138.2"	"184.4"	"168.2"	"171.3"	"190.4"	"233.7"	"250.8"	"620.0"	"1076.5"	"1489.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13017"	"Rho GTPase-activating protein 5 OS=Homo sapiens OX=9606 GN=ARHGAP5 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1502"	"172.4"	"6.62"	"520.80"	"5.34"	"1"	"1"	"cell adhesion;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00071, Pf00620, Pf01846, Pf16512, Pf19518"	"394"	"ENSG00000100852"	"ARHGAP5"	"A1L375; A1L376; A8KAA1; D3DS89; D3DS90; hsa:394; Q05BE8; Q05BU8; Q13017; Q59ER0; Q6DHZ3"	"Focal adhesion"	"RND2 GTPase cycle; RND1 GTPase cycle; RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RHOG GTPase cycle; RAC3 GTPase cycle; RHOB GTPase cycle; RHOD GTPase cycle; RHOJ GTPase cycle; RHOF GTPase cycle; RND3 GTPase cycle"	"15"	"0"	"9.4"	"13.1"	"11.8"	"8.8"	"14.0"	"13.4"	"12.8"	"25.3"	"106.9"	"162.1"	"205.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O76080"	"AN1-type zinc finger protein 5 OS=Homo sapiens OX=9606 GN=ZFAND5 PE=1 SV=1"	"8"	"1"	"2"	"1"	"213"	"23.1"	"8.51"	"451.36"	"5.34"	"1"	"1"	"developmental processes;signal transduction;other biological processes"	"other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01428, Pf01754"	"7763"	"ENSG00000107372"	"ZFAND5"	"A8K484; hsa:7763; O76080"	""	""	"0"	"0"	"32.6"	"26.4"	"33.0"	"26.2"	"43.8"	"45.8"	"58.9"	"101.4"	"179.3"	"262.8"	"299.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14908"	"PDZ domain-containing protein GIPC1 OS=Homo sapiens OX=9606 GN=GIPC1 PE=1 SV=2"	"4"	"1"	"2"	"1"	"333"	"36.0"	"6.28"	"525.11"	"5.33"	"1"	"1"	"cell-cell signaling;transport;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00595"	"10755"	"ENSG00000123159"	"GIPC1"	"A8K4I3; A8MZG3; hsa:10755; O14908; Q9BTC9"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"17.0"	"13.4"	"15.4"	"12.1"	"13.4"	"15.9"	"18.9"	"18.0"	"35.2"	"58.2"	"116.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NP61"	"ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1"	"4"	"2"	"4"	"2"	"516"	"56.9"	"7.36"	"783.14"	"5.33"	"2"	"2"	"cell organization and biogenesis;transport"	"other membranes;cytosol;ER/Golgi"	"enzyme regulator activity;other molecular function"	"Pf01412"	"26286"	"ENSG00000242247"	"ARFGAP3"	"E9PB03; hsa:26286; Q9BSC6; Q9H9J0; Q9NP61; Q9NT10; Q9NUP5; Q9Y4V3; Q9Y4V4"	"Ciliary landscape"	"COPI-mediated anterograde transport; CDC42 GTPase cycle; RHOG GTPase cycle; COPI-dependent Golgi-to-ER retrograde traffic"	"5"	"0"	"86.1"	"82.9"	"100.7"	"90.9"	"112.9"	"105.2"	"113.7"	"150.5"	"403.5"	"620.7"	"764.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99996"	"A-kinase anchor protein 9 OS=Homo sapiens OX=9606 GN=AKAP9 PE=1 SV=4"	"1"	"4"	"6"	"3"	"3907"	"452.7"	"4.98"	"1142.74"	"5.32"	"4"	"2"	"cell-cell signaling;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf10495"	"10142"	"ENSG00000127914"	"AKAP9"	"A4D1F0; A4D1F2; A4D1F4; hsa:10142; O14869; O43355; O94895; Q75N20; Q99996; Q9UQH3; Q9UQQ4; Q9Y6B8; Q9Y6Y2"	"G protein signaling pathways; NO/cGMP/PKG mediated neuroprotection"	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Signaling by BRAF and RAF1 fusions; Phase 3 - rapid repolarisation; Phase 2 - plateau phase"	"12"	"0"	"85.7"	"73.3"	"90.3"	"75.8"	"77.8"	"75.2"	"110.3"	"132.2"	"219.5"	"431.8"	"689.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62851"	"40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1"	"15"	"2"	"3"	"2"	"125"	"13.7"	"10.11"	"327.92"	"5.32"	"1"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf03297"	"6230"	"ENSG00000118181; ENSG00000280831"	"RPS25"	"B2R4M7; hsa:6230; P25111; P62851"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"47.9"	"41.6"	"60.6"	"45.9"	"55.1"	"49.9"	"73.5"	"83.3"	"128.2"	"224.1"	"269.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P78318"	"Immunoglobulin-binding protein 1 OS=Homo sapiens OX=9606 GN=IGBP1 PE=1 SV=1"	"6"	"1"	"1"	"1"	"339"	"39.2"	"5.38"	""	"5.32"	""	"1"	"signal transduction;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity;other molecular function"	"Pf04177"	"3476"	"ENSG00000089289"	"IGBP1"	"hsa:3476; P78318; Q8TAB2"	"16p11.2 proximal deletion syndrome"	""	"1"	"0"	"35.8"	"27.0"	"42.6"	"47.9"	"52.9"	"48.2"	"43.6"	"46.4"	"60.0"	"79.5"	"119.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BRP8"	"Partner of Y14 and mago OS=Homo sapiens OX=9606 GN=PYM1 PE=1 SV=1"	"13"	"2"	"5"	"2"	"204"	"22.6"	"9.45"	"853.09"	"5.32"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity"	"Pf09282"	"84305"	"ENSG00000170473"	"PYM1"	"B6ZDM5; hsa:84305; Q8IXJ8; Q8N8E7; Q9BRP8"	"TAR syndrome"	""	"1"	"0"	"71.3"	"79.8"	"59.3"	"60.1"	"62.0"	"71.2"	"86.9"	"97.6"	"173.4"	"248.7"	"261.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UNY4"	"Transcription termination factor 2 OS=Homo sapiens OX=9606 GN=TTF2 PE=1 SV=2"	"2"	"1"	"2"	"1"	"1162"	"129.5"	"8.37"	"775.78"	"5.30"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf06839"	"8458"	"ENSG00000116830"	"TTF2"	"A8K4Q2; hsa:8458; O75921; Q5T2K7; Q5VVU8; Q8N6I8; Q9UNY4"	"Thyroid stimulating hormone (TSH) signaling pathway; Thyroid hormones production and peripheral downstream signaling effects"	""	"2"	"0"	"43.1"	"41.9"	"45.8"	"52.0"	"56.8"	"37.8"	"65.2"	"73.7"	"164.6"	"280.9"	"457.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P10586"	"Receptor-type tyrosine-protein phosphatase F OS=Homo sapiens OX=9606 GN=PTPRF PE=1 SV=2"	"1"	"1"	"1"	"1"	"1907"	"212.7"	"6.30"	""	"5.29"	""	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00041, Pf00102, Pf07679"	"5792"	"ENSG00000142949"	"PTPRF"	"D3DPX6; D3DPX7; hsa:5792; P10586; Q5T021; Q5T022; Q5W9G2; Q86WS0"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; Insulin signaling"	"Insulin receptor recycling; Synaptic adhesion-like molecules; Receptor-type tyrosine-protein phosphatases"	"5"	"0"	"6.5"	"12.6"	"8.2"	"8.6"	"10.1"	"10.8"	"16.9"	"15.6"	"55.7"	"146.4"	"218.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z2W4"	"Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3"	"3"	"2"	"4"	"2"	"902"	"101.4"	"8.40"	"688.47"	"5.29"	"2"	"2"	"stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00644, Pf02825, Pf18606, Pf18633"	"56829"	"ENSG00000105939"	"ZC3HAV1"	"A4D1R2; A4D1S4; hsa:56829; Q7Z2W4; Q8IW57; Q8TAJ3; Q96N79; Q9H8R9; Q9P0Y7"	""	"Signaling by BRAF and RAF1 fusions"	"1"	"0"	"233.9"	"195.8"	"243.3"	"236.2"	"232.4"	"247.5"	"296.8"	"354.4"	"422.5"	"707.1"	"1022.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P5R6"	"60S ribosomal protein L22-like 1 OS=Homo sapiens OX=9606 GN=RPL22L1 PE=1 SV=2"	"20"	"1"	"1"	"1"	"122"	"14.6"	"9.38"	""	"5.29"	""	"1"	"protein metabolism;other metabolic processes"	"translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01776"	"200916"	"ENSG00000163584"	"RPL22L1"	"hsa:200916; Q32Q77; Q6P5R6"	""	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"13"	"0"	"32.0"	"39.5"	"36.3"	"28.5"	"38.0"	"34.8"	"36.2"	"45.7"	"137.8"	"206.2"	"206.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q06787"	"Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1"	"3"	"2"	"3"	"1"	"632"	"71.1"	"7.42"	"278.48"	"5.29"	"1"	"2"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"cytoskeletal activity;translation activity;nucleic acid binding activity;other molecular function"	"Pf00013, Pf05641, Pf12235, Pf16098, Pf17904, Pf18336"	"2332"	"ENSG00000102081"	"FMR1"	"A6NNH4; D3DWT0; D3DWT1; D3DWT2; G8JL90; hsa:2332; Q06787; Q16578; Q5PQZ6; Q99054"	"Ovarian infertility; Serotonin and anxiety; Prader-Willi and Angelman syndrome; Fragile X syndrome; Disruption of postsynaptic signaling by CNV; 15q11.2 copy number variation syndrome; Primary ovarian insufficiency"	""	"7"	"0"	"83.6"	"80.5"	"99.0"	"83.0"	"88.1"	"106.6"	"136.9"	"138.4"	"216.4"	"254.7"	"344.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96Q05"	"Trafficking protein particle complex subunit 9 OS=Homo sapiens OX=9606 GN=TRAPPC9 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1148"	"128.4"	"6.62"	"528.67"	"5.29"	"1"	"1"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf08626"	"83696"	"ENSG00000167632"	"TRAPPC9"	"hsa:83696; Q4VTT3; Q658K7; Q6P149; Q6ZQT3; Q7L5C4; Q86Y21; Q96Q05; Q96SL2; Q9BQA2"	""	"RAB GEFs exchange GTP for GDP on RABs; COPII-mediated vesicle transport"	"2"	"0"	"13.0"	"12.0"	"16.6"	"13.9"	"24.0"	"32.8"	"57.1"	"112.5"	"64.8"	"67.6"	"87.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TAE8"	"Growth arrest and DNA damage-inducible proteins-interacting protein 1 OS=Homo sapiens OX=9606 GN=GADD45GIP1 PE=1 SV=1"	"5"	"1"	"4"	"1"	"222"	"25.4"	"10.02"	"592.86"	"5.27"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	""	"Pf10147"	"90480"	"ENSG00000179271"	"GADD45GIP1"	"hsa:90480; Q8IVM3; Q8TAE8; Q8TE51; Q969P9; Q9BSM6"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"76.9"	"65.7"	"91.0"	"78.9"	"94.6"	"97.8"	"120.5"	"155.3"	"228.8"	"297.4"	"434.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P18846"	"Cyclic AMP-dependent transcription factor ATF-1 OS=Homo sapiens OX=9606 GN=ATF1 PE=1 SV=2"	"5"	"2"	"4"	"2"	"271"	"29.2"	"8.37"	"561.55"	"5.26"	"2"	"2"	"cell organization and biogenesis;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00170, Pf02173"	"466"	"ENSG00000123268"	"ATF1"	"B4DRF9; hsa:466; P18846; P25168; Q9H4A8"	"Integrated cancer pathway; Androgen receptor network in prostate cancer; Interleukin-11 signaling pathway; Myometrial relaxation and contraction pathways; EGF/EGFR signaling pathway; GDNF signaling; Serotonin receptor 4/6/7 and NR3C signaling"	"NGF-stimulated transcription; CREB phosphorylation"	"9"	"0"	"165.8"	"112.8"	"174.7"	"159.3"	"165.0"	"164.3"	"172.4"	"210.2"	"486.4"	"1017.2"	"1373.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49458"	"Signal recognition particle 9 kDa protein OS=Homo sapiens OX=9606 GN=SRP9 PE=1 SV=2"	"22"	"2"	"4"	"2"	"86"	"10.1"	"7.97"	"656.39"	"5.25"	"2"	"2"	"transport;other biological processes"	"other membranes;cytosol;ER/Golgi;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf05486"	"6726"	"ENSG00000143742"	"SRP9"	"A8K0N0; hsa:6726; P49458; Q6NVX0; Q8WTW0"	""	"SRP-dependent cotranslational protein targeting to membrane"	"1"	"0"	"121.4"	"152.5"	"115.7"	"92.9"	"138.1"	"142.9"	"188.1"	"328.0"	"674.6"	"693.3"	"1013.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WUM4"	"Programmed cell death 6-interacting protein OS=Homo sapiens OX=9606 GN=PDCD6IP PE=1 SV=1"	"3"	"2"	"3"	"2"	"868"	"96.0"	"6.52"	"327.24"	"5.24"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"non-structural extracellular;plasma membrane;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf03097, Pf13949"	"10015"	"ENSG00000170248"	"PDCD6IP"	"C5MQH7; E9PFU1; hsa:10015; Q6NUS1; Q8WUM4; Q9BX86; Q9NUN0; Q9P2H2; Q9UKL5"	"Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells"	"Budding and maturation of HIV virion; Regulation of necroptotic cell death; Uptake and function of anthrax toxins"	"5"	"0"	"7.6"	"7.4"	"11.7"	"10.4"	"10.7"	"10.1"	"15.2"	"20.5"	"24.0"	"67.9"	"140.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IWF6"	"Protein DENND6A OS=Homo sapiens OX=9606 GN=DENND6A PE=1 SV=1"	"2"	"1"	"2"	"1"	"608"	"69.5"	"8.27"	"575.66"	"5.24"	"1"	"1"	"other biological processes"	"cytosol;other cytoplasmic organelle;other cell component"	"enzyme regulator activity"	"Pf08616, Pf09794"	"201627"	"ENSG00000174839"	"DENND6A"	"hsa:201627; Q7Z5T4; Q8IWF6; Q8N235; Q8TEG8"	""	"RAB GEFs exchange GTP for GDP on RABs"	"1"	"0"	"31.5"	"26.4"	"28.4"	"22.8"	"27.8"	"34.6"	"39.2"	"40.1"	"54.0"	"71.8"	"66.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NYY8"	"FAST kinase domain-containing protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=FASTKD2 PE=1 SV=1"	"3"	"2"	"4"	"2"	"710"	"81.4"	"8.05"	"593.15"	"5.24"	"2"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"mitochondrion;other cell component"	"nucleic acid binding activity"	"Pf06743, Pf08368, Pf08373"	"22868"	"ENSG00000118246"	"FASTKD2"	"hsa:22868; Q9NVX6; Q9NYY8; Q9Y2H7"	""	""	"0"	"0"	"103.4"	"93.9"	"110.6"	"94.6"	"95.0"	"90.3"	"121.4"	"174.9"	"399.5"	"1030.6"	"1607.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P56211"	"cAMP-regulated phosphoprotein 19 OS=Homo sapiens OX=9606 GN=ARPP19 PE=1 SV=2"	"23"	"1"	"1"	"1"	"112"	"12.3"	"9.09"	""	"5.23"	""	"1"	"cell cycle OR cell proliferation;other biological processes"	"nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf04667"	"10776"	"ENSG00000128989"	"ARPP19"	"B2R497; hsa:10776; P56211; Q6IAM2; Q86TA6; Q9UD70"	""	"MASTL Facilitates Mitotic Progression"	"1"	"0"	"17.1"	"14.8"	"15.0"	"18.2"	"15.1"	"18.5"	"20.8"	"38.5"	"127.5"	"151.2"	"160.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H0W8"	"Protein SMG9 OS=Homo sapiens OX=9606 GN=SMG9 PE=1 SV=1"	"3"	"1"	"2"	"1"	"520"	"57.6"	"7.01"	"573.22"	"5.23"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes"	"cytosol"	"other molecular function"	"Pf10220"	"56006"	"ENSG00000105771"	"SMG9"	"hsa:56006; O60429; Q9H0W8; Q9H9A9"	""	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	"1"	"0"	"63.9"	"62.9"	"43.3"	"47.1"	"50.0"	"53.3"	"63.7"	"68.3"	"83.3"	"137.5"	"185.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96SB3"	"Neurabin-2 OS=Homo sapiens OX=9606 GN=PPP1R9B PE=1 SV=3"	"3"	"2"	"3"	"1"	"817"	"89.3"	"4.97"	"505.63"	"5.22"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;kinase activity;other molecular function"	"Pf00595, Pf17817"	"84687"	"ENSG00000108819"	"PPP1R9B"	"D3DTX6; hsa:84687; Q8TCR9; Q96SB3"	""	""	"0"	"0"	"8.7"	"10.6"	"14.9"	"11.4"	"12.2"	"13.3"	"19.7"	"16.2"	"49.1"	"74.9"	"93.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N5K1"	"CDGSH iron-sulfur domain-containing protein 2 OS=Homo sapiens OX=9606 GN=CISD2 PE=1 SV=1"	"11"	"1"	"2"	"1"	"135"	"15.3"	"9.61"	"508.72"	"5.22"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"other membranes;mitochondrion;ER/Golgi;other cell component"	"other molecular function"	"Pf09360, Pf10660"	"493856"	"ENSG00000145354"	"CISD2"	"hsa:493856; Q7Z3D5; Q8N5K1"	""	""	"0"	"0"	"32.9"	"31.1"	"36.4"	"42.6"	"45.8"	"38.9"	"53.2"	"65.0"	"174.4"	"287.4"	"355.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14185"	"Dedicator of cytokinesis protein 1 OS=Homo sapiens OX=9606 GN=DOCK1 PE=1 SV=2"	"0"	"1"	"4"	"1"	"1865"	"215.2"	"7.56"	"640.19"	"5.22"	"1"	"1"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00018, Pf06920, Pf14429, Pf16172, Pf20421, Pf20422"	"1793"	"ENSG00000150760"	"DOCK1"	"A9Z1Z5; hsa:1793; Q14185"	"Integrin-mediated cell adhesion; Androgen receptor network in prostate cancer; Focal adhesion; Hepatocyte growth factor receptor signaling; Regulation of actin cytoskeleton"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RAC1 GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; DCC mediated attractive signaling; VEGFA-VEGFR2 Pathway; Factors involved in megakaryocyte development and platelet production; PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"	"14"	"0"	"76.9"	"68.1"	"78.8"	"82.0"	"94.3"	"129.7"	"306.2"	"641.6"	"431.4"	"414.3"	"482.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4P3"	"Transducin beta-like protein 2 OS=Homo sapiens OX=9606 GN=TBL2 PE=1 SV=1"	"3"	"1"	"2"	"1"	"447"	"49.8"	"9.44"	"549.52"	"5.22"	"1"	"1"	"stress response;signal transduction"	"other membranes;ER/Golgi"	"other molecular function"	"Pf00400"	"26608"	"ENSG00000106638"	"TBL2"	"hsa:26608; Q9UQE2; Q9Y4P3"	"7q11.23 copy number variation syndrome"	""	"1"	"0"	"46.2"	"26.3"	"48.1"	"47.0"	"50.8"	"33.7"	"46.8"	"60.4"	"117.2"	"223.2"	"355.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NQW6"	"Anillin OS=Homo sapiens OX=9606 GN=ANLN PE=1 SV=2"	"2"	"1"	"2"	"1"	"1124"	"124.1"	"8.07"	"498.27"	"5.22"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf00169, Pf08174, Pf16018"	"54443"	"ENSG00000011426"	"ANLN"	"hsa:54443; Q5CZ78; Q6NSK5; Q9H8Y4; Q9NQW6; Q9NVN9; Q9NVP0"	"Retinoblastoma gene in cancer; Nephrotic syndrome"	"RHOC GTPase cycle; RHOA GTPase cycle; RHOB GTPase cycle"	"5"	"0"	"36.1"	"24.8"	"31.0"	"28.2"	"37.6"	"36.4"	"40.6"	"41.2"	"94.9"	"121.7"	"143.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95251"	"Histone acetyltransferase KAT7 OS=Homo sapiens OX=9606 GN=KAT7 PE=1 SV=1"	"4"	"1"	"1"	"1"	"611"	"70.6"	"8.85"	""	"5.21"	""	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01530, Pf01853, Pf17772"	"11143"	"ENSG00000136504"	"KAT7"	"B3KN74; B4DF85; B4DFB4; B4DFE0; B4DGY4; E7ER15; G5E9K7; hsa:11143; O95251"	"Androgen receptor signaling pathway"	"HATs acetylate histones"	"2"	"0"	"3.4"	"5.6"	"7.4"	"6.0"	"4.3"	"4.2"	"5.5"	"11.8"	"14.3"	"28.8"	"38.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UPW5"	"Cytosolic carboxypeptidase 1 OS=Homo sapiens OX=9606 GN=AGTPBP1 PE=1 SV=3"	"2"	"2"	"4"	"2"	"1226"	"138.4"	"6.15"	"532.63"	"5.21"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00246, Pf18027"	"23287"	"ENSG00000135049"	"AGTPBP1"	"B4DIT6; B4DRZ8; hsa:23287; Q5VV80; Q63HM7; Q658P5; Q6P9D6; Q9H8U6; Q9H9W8; Q9NVK1; Q9UPW5"	""	"Carboxyterminal post-translational modifications of tubulin"	"1"	"0"	"11.3"	"8.4"	"12.1"	"13.1"	"10.2"	"14.9"	"17.6"	"16.7"	"21.6"	"62.2"	"124.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NCA5"	"Protein FAM98A OS=Homo sapiens OX=9606 GN=FAM98A PE=1 SV=2"	"7"	"3"	"4"	"2"	"518"	"55.2"	"8.95"	"1070.02"	"5.21"	"3"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf10239"	"25940"	"ENSG00000119812"	"FAM98A"	"B2RNA2; hsa:25940; Q8NCA5; Q9Y3Y6"	""	""	"0"	"1"	"110.5"	"99.8"	"114.4"	"109.6"	"112.6"	"111.5"	"140.4"	"188.1"	"278.1"	"446.1"	"603.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NZ32"	"Actin-related protein 10 OS=Homo sapiens OX=9606 GN=ACTR10 PE=1 SV=1"	"5"	"1"	"2"	"1"	"417"	"46.3"	"7.37"	"393.99"	"5.20"	"1"	"1"	"transport"	"non-structural extracellular;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	""	"Pf00022"	"55860"	"ENSG00000131966"	"ACTR10"	"hsa:55860; Q9H9Y5; Q9NWY2; Q9NZ32"	""	"MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Neutrophil degranulation"	"5"	"0"	"8.8"	"10.0"	"12.7"	"10.1"	"12.6"	"14.6"	"14.8"	"22.5"	"41.0"	"66.4"	"90.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P21796"	"Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2"	"7"	"2"	"3"	"2"	"283"	"30.8"	"8.54"	"270.03"	"5.19"	"1"	"2"	"cell-cell signaling;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;mitochondrion;other cell component"	"transporter activity;other molecular function"	"Pf01459"	"7416"	"ENSG00000213585"	"VDAC1"	"B3KVK4; D3DQ93; hsa:7416; P21796; Q5FVE7; Q9UIQ5; Q9UPL0"	"Alzheimer's disease and miRNA effects; Alzheimer's disease; Arsenic metabolism and reactive oxygen species generation; Cholesterol metabolism; Fatty Acids and Lipoproteins Transport in Hepatocytes"	"Ub-specific processing proteases; Pyruvate metabolism; Mitochondrial protein import; PINK1-PRKN Mediated Mitophagy; Mitochondrial calcium ion transport"	"10"	"0"	"2.4"	"3.7"	"2.1"	"0.0"	"0.0"	"2.4"	"2.4"	"2.5"	"14.6"	"40.5"	"57.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q93034"	"Cullin-5 OS=Homo sapiens OX=9606 GN=CUL5 PE=1 SV=4"	"3"	"2"	"3"	"2"	"780"	"90.9"	"7.94"	"725.53"	"5.19"	"2"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;transport;signal transduction"	"cytosol;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf00888, Pf10557"	"8065"	"ENSG00000166266"	"CUL5"	"A8K960; hsa:8065; O14766; Q93034; Q9BZC6"	"Apoptosis-related network due to altered Notch3 in ovarian cancer; Dual hijack model of Vif in HIV infection; Modulators of TCR signaling and T cell activation; 10q11.21q11.23 copy number variation syndrome"	"Antigen processing: Ubiquitination & Proteasome degradation; Vif-mediated degradation of APOBEC3G; Neddylation; Inactivation of CSF3 (G-CSF) signaling; Downregulation of ERBB2 signaling"	"9"	"0"	"45.8"	"43.2"	"54.7"	"48.6"	"57.4"	"48.1"	"59.5"	"92.6"	"313.8"	"717.3"	"1062.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H814"	"Phosphorylated adapter RNA export protein OS=Homo sapiens OX=9606 GN=PHAX PE=1 SV=1"	"5"	"2"	"4"	"2"	"394"	"44.4"	"5.40"	"554.82"	"5.18"	"2"	"2"	"transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf10258"	"51808"	"ENSG00000164902"	"PHAX"	"hsa:51808; Q9H814; Q9H8W1"	""	"RNA polymerase II transcribes snRNA genes; snRNP Assembly"	"2"	"0"	"52.0"	"51.1"	"51.3"	"51.5"	"44.5"	"46.8"	"65.2"	"75.9"	"110.9"	"154.9"	"253.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62899"	"60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1"	"14"	"2"	"4"	"2"	"125"	"14.5"	"10.54"	"622.64"	"5.18"	"2"	"2"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01198"	"6160"	"ENSG00000071082"	"RPL31"	"B7Z4K2; D3DVJ4; hsa:6160; P12947; P62899; Q53SQ5; Q6IRZ0; Q6LBJ6"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis"	"14"	"0"	"107.6"	"113.0"	"93.7"	"92.1"	"106.1"	"101.0"	"120.9"	"171.5"	"254.6"	"456.5"	"703.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2S6"	"Translation machinery-associated protein 7 OS=Homo sapiens OX=9606 GN=TMA7 PE=1 SV=1"	"25"	"3"	"5"	"2"	"64"	"7.1"	"9.99"	"1058.61"	"5.18"	"3"	"2"	""	""	""	"Pf09072"	"51372"	"ENSG00000232112"	"TMA7"	"hsa:51372; Q9P052; Q9Y2S6"	""	""	"0"	"1"	"1598.3"	"1196.1"	"1395.3"	"1351.5"	"1267.6"	"1367.2"	"1668.6"	"1894.0"	"2730.3"	"2219.7"	"2126.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14649"	"Myosin light chain 6B OS=Homo sapiens OX=9606 GN=MYL6B PE=1 SV=1"	"8"	"1"	"2"	"1"	"208"	"22.8"	"5.73"	"445.16"	"5.17"	"1"	"1"	"other biological processes"	"cytosol;cytoskeleton"	"cytoskeletal activity;other molecular function"	""	"140465"	"ENSG00000196465"	"MYL6B"	"hsa:140465; P14649"	"Ciliary landscape"	"Smooth Muscle Contraction"	"2"	"0"	"8.0"	"7.7"	"11.9"	"4.5"	"12.2"	"7.3"	"12.2"	"16.0"	"34.6"	"68.1"	"87.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y657"	"Spindlin-1 OS=Homo sapiens OX=9606 GN=SPIN1 PE=1 SV=3"	"6"	"1"	"2"	"1"	"262"	"29.6"	"6.96"	"432.37"	"5.17"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus"	"other molecular function"	"Pf02513"	"10927"	"ENSG00000106723"	"SPIN1"	"A8K0X6; B3KRQ4; hsa:10927; Q7KZJ8; Q9GZT2; Q9H0N7; Q9Y657"	""	""	"0"	"0"	"41.5"	"36.7"	"34.8"	"35.5"	"36.5"	"39.4"	"43.1"	"63.6"	"114.2"	"204.3"	"228.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H7B2"	"Ribosome production factor 2 homolog OS=Homo sapiens OX=9606 GN=RPF2 PE=1 SV=2"	"6"	"1"	"2"	"1"	"306"	"35.6"	"9.99"	"456.63"	"5.17"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf04427"	"84154"	"ENSG00000197498"	"RPF2"	"hsa:84154; Q5VXN1; Q8N4A1; Q9H7B2"	""	""	"0"	"0"	"52.3"	"28.6"	"62.2"	"64.7"	"62.3"	"46.6"	"58.6"	"74.7"	"116.1"	"176.3"	"301.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q68DK7"	"Male-specific lethal 1 homolog OS=Homo sapiens OX=9606 GN=MSL1 PE=1 SV=3"	"3"	"1"	"2"	"1"	"614"	"67.1"	"8.92"	"465.44"	"5.16"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf15275, Pf16801"	"339287"	"ENSG00000188895"	"MSL1"	"hsa:339287; Q0VF46; Q68DK7; Q69Z03"	""	"HATs acetylate histones"	"1"	"0"	"28.0"	"17.6"	"30.1"	"25.5"	"25.2"	"24.9"	"26.8"	"35.8"	"60.5"	"75.8"	"87.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P54619"	"5'-AMP-activated protein kinase subunit gamma-1 OS=Homo sapiens OX=9606 GN=PRKAG1 PE=1 SV=1"	"6"	"1"	"2"	"1"	"331"	"37.6"	"6.92"	"532.49"	"5.16"	"1"	"1"	"protein metabolism;other metabolic processes;transport;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00571"	"5571"	"ENSG00000181929"	"PRKAG1"	"B4DDT7; hsa:5571; P54619; Q8N7V9"	"AMP-activated protein kinase signaling; Target of rapamycin signaling; Energy metabolism; Sterol regulatory element-binding proteins (SREBP) signaling; Angiopoietin-like protein 8 regulatory pathway; Leptin and adiponectin; Lipid metabolism pathway; Thermogenesis; Nonalcoholic fatty liver disease; Synaptic signaling pathways associated with autism spectrum disorder; Hippo signaling regulation pathways; 1q21.1 copy number variation syndrome; Autophagy; p53 transcriptional gene network; Pleural mesothelioma"	"Regulation of TP53 Activity through Phosphorylation; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Activation of AMPK downstream of NMDARs; TP53 Regulates Metabolic Genes; Macroautophagy; Energy dependent regulation of mTOR by LKB1-AMPK; Activation of PPARGC1A (PGC-1alpha) by phosphorylation; Lipophagy"	"23"	"0"	"3.8"	"3.2"	"4.7"	"0.0"	"4.6"	"0.0"	"3.5"	"3.5"	"29.4"	"110.9"	"164.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q4KMP7"	"TBC1 domain family member 10B OS=Homo sapiens OX=9606 GN=TBC1D10B PE=1 SV=3"	"3"	"1"	"1"	"1"	"808"	"87.1"	"9.19"	""	"5.16"	""	"1"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol"	"enzyme regulator activity"	"Pf00566"	"26000"	"ENSG00000169221"	"TBC1D10B"	"B9A6L0; hsa:26000; Q4KMP7; Q6IN54; Q6P530; Q71RG7; Q86VC5; Q9H8Z2; Q9NUN6; Q9UFP2"	""	"TBC/RABGAPs"	"1"	"0"	"62.1"	"36.9"	"108.2"	"50.4"	"126.7"	"69.6"	"100.0"	"94.7"	"110.3"	"124.2"	"115.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9GZN1"	"Actin-related protein 6 OS=Homo sapiens OX=9606 GN=ACTR6 PE=1 SV=1"	"5"	"1"	"1"	"1"	"396"	"45.8"	"5.03"	""	"5.15"	""	"1"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00022"	"64431"	"ENSG00000075089"	"ACTR6"	"B3KW37; B4DLG9; hsa:64431; Q53GH2; Q9BY39; Q9GZN1; Q9H8H6"	""	""	"0"	"0"	"6.2"	"4.3"	"4.9"	"2.2"	"3.1"	"6.1"	"8.0"	"11.2"	"39.6"	"171.3"	"215.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N5N7"	"39S ribosomal protein L50, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL50 PE=1 SV=2"	"13"	"1"	"2"	"1"	"158"	"18.3"	"7.88"	"437.41"	"5.14"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;cytosol;mitochondrion;translational apparatus"	""	"Pf10501"	"54534"	"ENSG00000136897"	"MRPL50"	"B7Z358; hsa:54534; Q5T7E0; Q8N5N7; Q9NX15"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"3.0"	"9.0"	"2.9"	"4.3"	"7.3"	"9.1"	"8.1"	"15.7"	"35.0"	"60.3"	"79.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P47914"	"60S ribosomal protein L29 OS=Homo sapiens OX=9606 GN=RPL29 PE=1 SV=2"	"13"	"2"	"3"	"2"	"159"	"17.7"	"11.66"	"395.46"	"5.12"	"1"	"2"	"protein metabolism;other metabolic processes;developmental processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01779"	"6159"	"ENSG00000162244"	"RPL29"	"A8K0H3; B2R4M8; hsa:6159; P47914; Q6IPY3"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"532.9"	"505.8"	"556.9"	"464.8"	"456.1"	"538.7"	"631.3"	"754.8"	"980.8"	"1484.9"	"2334.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A5PLN9"	"Trafficking protein particle complex subunit 13 OS=Homo sapiens OX=9606 GN=TRAPPC13 PE=1 SV=2"	"4"	"1"	"2"	"1"	"417"	"46.5"	"5.60"	"609.19"	"5.11"	"1"	"1"	"cell organization and biogenesis;transport"	"cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf06159"	"80006"	"ENSG00000113597"	"TRAPPC13"	"A5PLN9; hsa:80006; Q17RZ9; Q49A23; Q4JHG0; Q6MZG4; Q8TCM2; Q9H8I3"	""	"RAB GEFs exchange GTP for GDP on RABs"	"1"	"0"	"7.4"	"5.5"	"11.6"	"6.8"	"9.2"	"9.4"	"15.3"	"31.6"	"116.2"	"193.7"	"344.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P53618"	"Coatomer subunit beta OS=Homo sapiens OX=9606 GN=COPB1 PE=1 SV=3"	"4"	"2"	"3"	"2"	"953"	"107.1"	"6.05"	"815.22"	"5.11"	"2"	"1"	"transport"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf01602, Pf07718, Pf14806"	"1315"	"ENSG00000129083"	"COPB1"	"D3DQX0; hsa:1315; P53618; Q6GTT7; Q9NTK2; Q9UNW7"	""	"COPI-dependent Golgi-to-ER retrograde traffic; Neutrophil degranulation; COPI-mediated anterograde transport"	"3"	"0"	"14.0"	"14.4"	"19.4"	"19.3"	"22.7"	"14.6"	"17.9"	"24.2"	"42.3"	"80.1"	"127.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00443"	"Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2"	"1"	"1"	"1"	"1"	"1686"	"190.6"	"8.02"	""	"5.10"	""	"1"	"cell organization and biogenesis;other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00168, Pf00454, Pf00613, Pf00787, Pf00792, Pf00794"	"5286"	"ENSG00000011405"	"PIK3C2A"	"B0LPH2; B4E2G4; hsa:5286; O00443; Q14CQ9"	"Glioblastoma signaling pathways; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Microglia pathogen phagocytosis pathway; Osteoblast differentiation and related diseases; Insulin signaling; Regulation of actin cytoskeleton; DNA damage response (only ATM dependent)"	"Golgi Associated Vesicle Biogenesis; Clathrin-mediated endocytosis; Synthesis of PIPs at the plasma membrane; Synthesis of PIPs at the Golgi membrane; Synthesis of PIPs at the early endosome membrane; Synthesis of PIPs at the late endosome membrane"	"14"	"0"	"6.4"	"8.4"	"9.0"	"6.7"	"9.4"	"11.3"	"13.8"	"13.7"	"30.0"	"62.0"	"58.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NEY8"	"Periphilin-1 OS=Homo sapiens OX=9606 GN=PPHLN1 PE=1 SV=2"	"3"	"2"	"3"	"2"	"458"	"52.7"	"9.11"	"337.25"	"5.10"	"1"	"2"	"cell organization and biogenesis;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	""	"Pf11488"	"51535"	"ENSG00000134283"	"PPHLN1"	"E9PAX8; hsa:51535; Q86YT2; Q8IXN3; Q8NEY8; Q8TB09; Q96NB9; Q9NXL4; Q9P0P6; Q9P0R9"	""	""	"0"	"0"	"488.9"	"452.3"	"550.4"	"478.9"	"547.8"	"509.0"	"575.8"	"621.9"	"686.8"	"1108.5"	"1709.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2R9"	"28S ribosomal protein S7, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS7 PE=1 SV=2"	"5"	"1"	"2"	"1"	"242"	"28.1"	"9.99"	"416.70"	"5.09"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00177"	"51081"	"ENSG00000125445"	"MRPS7"	"B2R9N5; hsa:51081; Q53GD6; Q9Y2R9"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"60.4"	"62.9"	"63.3"	"59.7"	"68.8"	"66.1"	"75.0"	"74.8"	"226.3"	"300.0"	"437.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WXC6"	"COP9 signalosome complex subunit 9 OS=Homo sapiens OX=9606 GN=COPS9 PE=1 SV=3"	"35"	"1"	"2"	"1"	"57"	"6.2"	"3.83"	"351.43"	"5.09"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	""	"Pf15004"	"150678"	"ENSG00000172428"	"COPS9"	"hsa:150678; Q8N110; Q8WXC6"	"2q37 copy number variation syndrome"	""	"1"	"0"	"0.0"	"4.3"	"9.1"	"3.8"	"4.8"	"8.9"	"4.9"	"13.2"	"34.5"	"66.6"	"139.7"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P20618"	"Proteasome subunit beta type-1 OS=Homo sapiens OX=9606 GN=PSMB1 PE=1 SV=2"	"8"	"1"	"2"	"1"	"241"	"26.5"	"8.13"	"380.98"	"5.08"	"1"	"1"	"protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	""	"Pf00227"	"5689"	"ENSG00000008018"	"PSMB1"	"B5BU76; hsa:5689; P20618; Q9BWA8"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A; MAPK6/MAPK4 signaling; The role of GTSE1 in G2/M progression after G2 checkpoint; Neutrophil degranulation; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"63"	"0"	"30.3"	"31.8"	"34.2"	"39.1"	"36.4"	"35.6"	"35.0"	"46.5"	"73.5"	"150.9"	"325.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13405"	"39S ribosomal protein L49, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL49 PE=1 SV=1"	"7"	"1"	"3"	"1"	"166"	"19.2"	"9.45"	"344.20"	"5.08"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf05046"	"740"	"ENSG00000149792"	"MRPL49"	"B2R4G6; hsa:740; Q13405"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"32.8"	"39.9"	"38.0"	"27.8"	"31.4"	"41.3"	"55.1"	"66.5"	"137.8"	"241.3"	"307.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96ES7"	"SAGA-associated factor 29 OS=Homo sapiens OX=9606 GN=SGF29 PE=1 SV=1"	"4"	"1"	"2"	"1"	"293"	"33.2"	"8.10"	"508.89"	"5.08"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf07039"	"112869"	"ENSG00000176476"	"SGF29"	"hsa:112869; Q96ES7; Q96MF5"	""	"Formation of WDR5-containing histone-modifying complexes; HATs acetylate histones"	"2"	"0"	"28.8"	"30.6"	"38.4"	"28.6"	"33.9"	"40.3"	"41.9"	"54.0"	"152.6"	"229.7"	"228.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BXY0"	"Protein MAK16 homolog OS=Homo sapiens OX=9606 GN=MAK16 PE=1 SV=2"	"4"	"1"	"2"	"1"	"300"	"35.3"	"5.38"	"409.90"	"5.08"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf01778, Pf04874"	"84549"	"ENSG00000198042"	"MAK16"	"B2RB44; hsa:84549; Q5U5T1; Q86UC4; Q96SY6; Q9BXY0"	""	""	"0"	"0"	"102.1"	"95.3"	"99.6"	"82.9"	"109.3"	"102.0"	"117.1"	"129.0"	"149.2"	"221.1"	"349.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9C0D5"	"Protein TANC1 OS=Homo sapiens OX=9606 GN=TANC1 PE=1 SV=3"	"1"	"2"	"4"	"1"	"1861"	"202.1"	"8.32"	"528.78"	"5.06"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"other cell component"	""	"Pf00023, Pf12796"	"85461"	"ENSG00000115183"	"TANC1"	"C9JD88; hsa:85461; Q49AI8; Q9C0D5"	""	""	"0"	"1"	"153.6"	"112.1"	"164.0"	"148.3"	"153.1"	"154.8"	"190.6"	"241.5"	"373.9"	"421.4"	"568.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62879"	"Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 OS=Homo sapiens OX=9606 GN=GNB2 PE=1 SV=3"	"5"	"1"	"2"	"1"	"340"	"37.3"	"6.00"	"473.22"	"5.06"	"1"	"1"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00400"	"2783"	"ENSG00000172354"	"GNB2"	"B3KPU1; hsa:2783; P11016; P54312; P62879"	"Corticotropin-releasing hormone signaling pathway; Myometrial relaxation and contraction pathways; G protein signaling pathways; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Ras signaling; Calcium regulation in cardiac cells"	"G alpha (i) signalling events; G alpha (12/13) signalling events; G alpha (q) signalling events; G alpha (z) signalling events; ADP signalling through P2Y purinoceptor 12; Extra-nuclear estrogen signaling; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production; Thrombin signalling through proteinase activated receptors (PARs); Activation of G protein gated Potassium channels; G-protein activation; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; G beta:gamma signalling through PI3Kgamma; Prostacyclin signalling through prostacyclin receptor; Adrenaline,noradrenaline inhibits insulin secretion; Ca2+ pathway; G beta:gamma signalling through PLC beta; ADP signalling through P2Y purinoceptor 1; Glucagon-type ligand receptors; Thromboxane signalling through TP receptor; Vasopressin regulates renal water homeostasis via Aquaporins; Presynaptic function of Kainate receptors; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; G beta:gamma signalling through BTK; G beta:gamma signalling through CDC42; Inhibition  of voltage gated Ca2+ channels via Gbeta/gamma subunits; Glucagon signaling in metabolic regulation"	"36"	"0"	"22.5"	"18.3"	"21.6"	"22.0"	"25.1"	"25.8"	"26.3"	"42.3"	"82.5"	"241.6"	"382.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61077"	"Ubiquitin-conjugating enzyme E2 D3 OS=Homo sapiens OX=9606 GN=UBE2D3 PE=1 SV=1"	"16"	"1"	"1"	"1"	"147"	"16.7"	"7.80"	""	"5.06"	""	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00179"	"7323"	"ENSG00000109332"	"UBE2D3"	"A6NJ93; A6NJB1; A6NM99; hsa:7323; P47986; P61077; Q6IB88; Q6NXS4; Q8N924"	"Proteasome degradation"	"Antigen processing: Ubiquitination & Proteasome degradation; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Neddylation; E3 ubiquitin ligases ubiquitinate target proteins; Peroxisomal protein import; IKK complex recruitment mediated by RIP1; Signaling by BMP; Inactivation of CSF3 (G-CSF) signaling; TICAM1, RIP1-mediated IKK complex recruitment; Regulation of TNFR1 signaling; Negative regulators of DDX58/IFIH1 signaling; Downregulation of SMAD2/3:SMAD4 transcriptional activity"	"13"	"0"	"4.2"	"0.0"	"4.5"	"5.2"	"6.4"	"5.3"	"6.9"	"6.8"	"13.4"	"37.1"	"73.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P2W1"	"Homologous-pairing protein 2 homolog OS=Homo sapiens OX=9606 GN=PSMC3IP PE=1 SV=1"	"10"	"2"	"3"	"2"	"217"	"24.9"	"7.81"	"913.04"	"5.05"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf07106, Pf18517"	"29893"	"ENSG00000131470"	"PSMC3IP"	"C5ILB7; hsa:29893; Q14458; Q8WXG2; Q96HA2; Q9P2W1"	"Androgen receptor signaling pathway; Primary ovarian insufficiency"	"Meiotic recombination"	"3"	"0"	"28.8"	"36.2"	"34.8"	"30.4"	"39.5"	"31.4"	"55.4"	"61.5"	"135.3"	"229.6"	"241.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15435"	"Protein phosphatase 1 regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PPP1R7 PE=1 SV=1"	"8"	"2"	"3"	"2"	"360"	"41.5"	"4.91"	"814.83"	"5.04"	"2"	"1"	"other biological processes"	"other cell component"	"enzyme regulator activity"	"Pf14580"	"5510"	"ENSG00000115685"	"PPP1R7"	"B4DFD4; B5MCY6; hsa:5510; Q15435; Q9UQE5; Q9UQE6; Q9Y6K4"	"2q37 copy number variation syndrome"	""	"1"	"0"	"24.7"	"22.5"	"21.4"	"21.9"	"21.9"	"16.7"	"15.8"	"31.0"	"80.4"	"195.2"	"360.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WYQ5"	"Microprocessor complex subunit DGCR8 OS=Homo sapiens OX=9606 GN=DGCR8 PE=1 SV=1"	"3"	"2"	"4"	"2"	"773"	"86.0"	"5.95"	"539.69"	"5.03"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00035"	"54487"	"ENSG00000128191"	"DGCR8"	"B2R8G1; hsa:54487; Q6DCB2; Q6MZE9; Q6Y2L0; Q8WYQ5; Q96G39; Q96GP8; Q9H6L8; Q9H6T7; Q9NRW2"	"miRNA biogenesis; exRNA mechanism of action and biogenesis; DDX1 as a regulatory component of the Drosha microprocessor; 22q11.2 copy number variation syndrome"	"Transcriptional Regulation by MECP2; MicroRNA (miRNA) biogenesis"	"6"	"0"	"26.7"	"30.4"	"28.0"	"21.2"	"28.9"	"30.5"	"39.3"	"45.1"	"58.5"	"107.5"	"161.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9C0B5"	"Palmitoyltransferase ZDHHC5 OS=Homo sapiens OX=9606 GN=ZDHHC5 PE=1 SV=2"	"3"	"1"	"1"	"1"	"715"	"77.5"	"9.01"	""	"5.03"	""	"1"	"protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf01529"	"25921"	"ENSG00000156599"	"ZDHHC5"	"hsa:25921; Q2TGF0; Q6ZMF0; Q8TAK8; Q9C0B5; Q9H923; Q9UFI7"	""	"Maturation of spike protein"	"1"	"0"	"37.1"	"32.4"	"38.7"	"38.0"	"33.8"	"36.2"	"43.2"	"48.0"	"130.6"	"254.4"	"335.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q76FK4"	"Nucleolar protein 8 OS=Homo sapiens OX=9606 GN=NOL8 PE=1 SV=1"	"2"	"2"	"4"	"2"	"1167"	"131.5"	"7.09"	"516.57"	"5.02"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf00076"	"55035"	"ENSG00000198000"	"NOL8"	"hsa:55035; Q5TCC7; Q5TCC8; Q5TCD3; Q5TCD5; Q5TCD6; Q5TCD7; Q76D35; Q76FK4; Q7L3E2; Q9H586; Q9H795; Q9H7W7; Q9H9J6; Q9NWA4; Q9NWM4"	""	""	"0"	"0"	"9.1"	"12.8"	"13.7"	"10.8"	"12.8"	"15.2"	"15.4"	"25.2"	"38.5"	"62.0"	"79.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92769"	"Histone deacetylase 2 OS=Homo sapiens OX=9606 GN=HDAC2 PE=1 SV=2"	"12"	"4"	"4"	"3"	"488"	"55.3"	"5.91"	"908.66"	"5.02"	"3"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00850"	"3066"	"ENSG00000196591"	"HDAC2"	"B3KRS5; B4DL58; E1P561; hsa:3066; Q5SRI8; Q5SZ86; Q8NEH4; Q92769"	"Cell cycle; Neural crest differentiation; Notch signaling; Initiation of transcription and translation elongation at the HIV-1 LTR; Ethanol effects on histone modifications; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; Ciliary landscape; 7q11.23 copy number variation syndrome; SARS-CoV-2 innate immunity evasion and cell-specific immune response; TAR syndrome; Notch signaling pathway"	"NoRC negatively regulates rRNA expression; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of TP53 Activity through Acetylation; Potential therapeutics for SARS; SUMOylation of chromatin organization proteins; HDACs deacetylate histones; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes; Regulation of PTEN gene transcription; Factors involved in megakaryocyte development and platelet production; RNA Polymerase I Transcription Initiation; p75NTR negatively regulates cell cycle via SC1; NOTCH1 Intracellular Domain Regulates Transcription; Notch-HLH transcription pathway; Regulation of MECP2 expression and activity; STAT3 nuclear events downstream of ALK signaling; EGR2 and SOX10-mediated initiation of Schwann cell myelination; MECP2 regulates neuronal receptors and channels"	"30"	"1"	"186.5"	"129.9"	"212.9"	"197.7"	"184.3"	"211.5"	"230.0"	"278.1"	"426.7"	"748.6"	"1197.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00423"	"Echinoderm microtubule-associated protein-like 1 OS=Homo sapiens OX=9606 GN=EML1 PE=1 SV=3"	"2"	"2"	"4"	"2"	"815"	"89.8"	"7.06"	"660.61"	"5.01"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400, Pf03451"	"2009"	"ENSG00000066629"	"EML1"	"hsa:2009; O00423; Q86U15; Q8N536; Q8N5C4; Q8WWL6"	""	""	"0"	"0"	"67.7"	"54.8"	"72.4"	"72.5"	"73.9"	"69.9"	"92.3"	"110.6"	"204.3"	"471.9"	"685.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UJA5"	"tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 OS=Homo sapiens OX=9606 GN=TRMT6 PE=1 SV=1"	"4"	"1"	"1"	"1"	"497"	"55.8"	"7.55"	""	"5.01"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf04189"	"51605"	"ENSG00000089195"	"TRMT6"	"B4DUV6; hsa:51605; Q76P92; Q9BQV5; Q9UJA5; Q9ULR7; Q9Y2Z8"	""	"tRNA modification in the nucleus and cytosol"	"1"	"0"	"21.8"	"25.9"	"24.7"	"25.2"	"20.4"	"26.9"	"39.3"	"35.2"	"60.9"	"102.6"	"149.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35244"	"Replication protein A 14 kDa subunit OS=Homo sapiens OX=9606 GN=RPA3 PE=1 SV=1"	"18"	"1"	"1"	"1"	"121"	"13.6"	"5.08"	""	"5.01"	""	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf08661"	"6119"	"ENSG00000106399"	"RPA3"	"hsa:6119; P35244; Q549U6"	"Retinoblastoma gene in cancer; G1 to S cell cycle control; DNA replication; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"HSF1 activation; Fanconi Anemia Pathway; Regulation of HSF1-mediated heat shock response; Regulation of TP53 Activity through Phosphorylation; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Meiotic recombination; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Removal of the Flap Intermediate; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"36"	"0"	"55.6"	"48.5"	"66.8"	"59.9"	"65.3"	"52.8"	"74.1"	"95.5"	"141.9"	"196.5"	"329.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P28070"	"Proteasome subunit beta type-4 OS=Homo sapiens OX=9606 GN=PSMB4 PE=1 SV=4"	"9"	"1"	"1"	"1"	"264"	"29.2"	"5.97"	""	"5.00"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00227"	"5692"	"ENSG00000159377"	"PSMB4"	"B2R9L3; hsa:5692; P28070; P31148; Q5SZS5; Q6IBI4; Q969L6"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Regulation of expression of SLITs and ROBOs; Regulation of PTEN stability and activity; KEAP1-NFE2L2 pathway; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Neddylation; Interleukin-1 signaling; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"62"	"0"	"7.1"	"9.0"	"5.1"	"8.1"	"6.1"	"6.6"	"6.0"	"7.4"	"8.9"	"16.9"	"52.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13561"	"Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4"	"4"	"2"	"3"	"2"	"401"	"44.2"	"5.21"	"250.93"	"4.99"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf04912"	"10540"	"ENSG00000175203"	"DCTN2"	"B2RBK5; hsa:10540; Q13561; Q86YN2; Q9BW17"	""	"MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Recruitment of NuMA to mitotic centrosomes; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"11"	"0"	"91.7"	"88.9"	"84.8"	"59.8"	"76.9"	"91.3"	"111.5"	"139.1"	"336.9"	"929.2"	"1973.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86YB8"	"ERO1-like protein beta OS=Homo sapiens OX=9606 GN=ERO1B PE=1 SV=2"	"5"	"2"	"4"	"2"	"467"	"53.5"	"7.99"	"564.11"	"4.96"	"2"	"2"	"protein metabolism;other metabolic processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf04137"	"56605"	"ENSG00000086619"	"ERO1B"	"B4DF57; hsa:56605; Q5T1H4; Q86YB8; Q8IZ11; Q9NR62"	""	"Insulin processing"	"1"	"0"	"4.2"	"2.8"	"2.0"	"4.7"	"5.3"	"1.9"	"9.0"	"17.5"	"52.2"	"85.5"	"130.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94874"	"E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2"	"3"	"2"	"4"	"2"	"794"	"89.5"	"6.79"	"576.57"	"4.96"	"2"	"2"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf09743"	"23376"	"ENSG00000014123"	"UFL1"	"A0PJ53; B4DJ57; C0H5X5; hsa:23376; O94874; Q8N765; Q9NTQ0"	""	"Antigen processing: Ubiquitination & Proteasome degradation"	"1"	"0"	"27.2"	"31.8"	"39.4"	"29.4"	"35.4"	"35.9"	"36.5"	"57.0"	"183.4"	"374.7"	"445.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15843"	"NEDD8 OS=Homo sapiens OX=9606 GN=NEDD8 PE=1 SV=1"	"17"	"1"	"2"	"1"	"81"	"9.1"	"8.43"	"600.14"	"4.96"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00240"	"4738"	"ENSG00000129559; ENSG00000285246"	"NEDD8"	"hsa:4738; Q15843; Q3SXN8; Q6LES6"	"EGF/EGFR signaling pathway; 2q37 copy number variation syndrome"	"UCH proteinases; Neddylation; Cargo recognition for clathrin-mediated endocytosis; Iron uptake and transport; TGF-beta receptor signaling activates SMADs"	"7"	"0"	"141.4"	"141.4"	"157.8"	"162.7"	"151.9"	"140.7"	"167.5"	"205.7"	"309.1"	"633.9"	"1331.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H410"	"Kinetochore-associated protein DSN1 homolog OS=Homo sapiens OX=9606 GN=DSN1 PE=1 SV=2"	"4"	"1"	"2"	"1"	"356"	"40.0"	"7.05"	"388.26"	"4.95"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cytoplasmic organelle;other cell component"	""	"Pf08202"	"79980"	"ENSG00000149636"	"DSN1"	"B4DWT2; E1P5U9; hsa:79980; Q5JW55; Q5JW56; Q9H410; Q9H8P4"	""	"Neutrophil degranulation; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"7"	"0"	"15.5"	"14.0"	"33.0"	"22.4"	"24.5"	"25.2"	"28.7"	"37.8"	"100.5"	"195.7"	"237.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N1N4"	"Keratin, type II cytoskeletal 78 OS=Homo sapiens OX=9606 GN=KRT78 PE=1 SV=2"	"4"	"2"	"2"	"1"	"520"	"56.8"	"6.02"	""	"4.94"	""	"2"	"other biological processes"	"cytosol;cytoskeleton"	"bone, tooth or skin structural activity"	"Pf00038, Pf16208"	"196374"	"ENSG00000170423"	"KRT78"	"A8K4D6; hsa:196374; Q5HYM7; Q7RTT2; Q8N1N4"	""	"Formation of the cornified envelope"	"2"	"0"	"20.8"	"23.5"	"27.1"	"16.5"	"38.0"	"23.2"	"24.0"	"39.3"	"100.2"	"243.1"	"277.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5W0B1"	"ORC ubiquitin ligase 1 OS=Homo sapiens OX=9606 GN=OBI1 PE=1 SV=1"	"4"	"2"	"4"	"2"	"726"	"81.1"	"5.72"	"739.52"	"4.94"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"other cell component"	"other molecular function"	"Pf13923"	"79596"	"ENSG00000152193"	"OBI1"	"B2RN99; hsa:79596; Q5W0B1; Q8TBY2; Q9H0T2; Q9H8M0"	""	""	"0"	"0"	"96.5"	"75.6"	"115.3"	"98.0"	"123.8"	"98.8"	"126.1"	"127.8"	"216.5"	"422.2"	"665.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51114"	"Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3"	"5"	"3"	"5"	"2"	"621"	"69.7"	"6.15"	"1334.27"	"4.94"	"3"	"2"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf05641, Pf12235, Pf16096, Pf16097, Pf17904, Pf18336"	"8087"	"ENSG00000114416"	"FXR1"	"A8K9B8; hsa:8087; P51114; Q7Z450; Q8N6R8"	"Bile acids synthesis and enterohepatic circulation"	"Signaling by BRAF and RAF1 fusions"	"2"	"1"	"241.5"	"200.7"	"265.3"	"237.0"	"255.0"	"272.5"	"307.1"	"368.2"	"545.8"	"1122.6"	"1738.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96RT1"	"Erbin OS=Homo sapiens OX=9606 GN=ERBIN PE=1 SV=2"	"2"	"2"	"4"	"2"	"1412"	"158.2"	"5.50"	"472.63"	"4.93"	"2"	"2"	"cell adhesion;cell organization and biogenesis;transport;signal transduction;other biological processes"	"extracellular matrix;plasma membrane;other membranes;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity"	"Pf00595, Pf13855"	"55914"	"ENSG00000112851"	"ERBIN"	"A0AVR1; B4E3F1; B7ZLV9; E7EQW9; E9PCR8; hsa:55914; Q1RMD0; Q86W38; Q96RT1; Q9NR18; Q9NW48; Q9ULJ5"	"Nucleotide-binding oligomerization domain (NOD) pathway; Nod-like receptor (NLR) signaling pathway; Pathways affected in adenoid cystic carcinoma"	"RHOC GTPase cycle; RHOA GTPase cycle; RHOB GTPase cycle; RAC1 GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; Downregulation of ERBB2 signaling; Signaling by ERBB2 KD Mutants; Signaling by ERBB2 TMD/JMD mutants; Signaling by ERBB2 ECD mutants; Constitutive Signaling by Overexpressed ERBB2; Drug-mediated inhibition of ERBB2 signaling; Resistance of ERBB2 KD mutants to trastuzumab; Resistance of ERBB2 KD mutants to sapitinib; Resistance of ERBB2 KD mutants to tesevatinib; Resistance of ERBB2 KD mutants to neratinib; Resistance of ERBB2 KD mutants to osimertinib; Resistance of ERBB2 KD mutants to afatinib; Resistance of ERBB2 KD mutants to AEE788; Resistance of ERBB2 KD mutants to lapatinib; Drug resistance in ERBB2 TMD/JMD mutants"	"26"	"0"	"3.0"	"4.3"	"10.4"	"5.9"	"13.2"	"6.8"	"10.9"	"21.6"	"33.7"	"55.3"	"58.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P43250"	"G protein-coupled receptor kinase 6 OS=Homo sapiens OX=9606 GN=GRK6 PE=1 SV=2"	"4"	"2"	"4"	"2"	"576"	"65.9"	"8.00"	"518.04"	"4.93"	"2"	"2"	"cell-cell signaling;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00615"	"2870"	"ENSG00000198055"	"GRK6"	"hsa:2870; O60541; P43250; Q13652"	"Follicle stimulating hormone (FSH) signaling pathway; Corticotropin-releasing hormone signaling pathway; Myometrial relaxation and contraction pathways; Chemokine signaling pathway; Calcium regulation in cardiac cells; 5q35 copy number variation"	"G alpha (s) signalling events"	"7"	"0"	"56.5"	"53.8"	"60.5"	"48.3"	"59.9"	"54.9"	"94.7"	"171.0"	"237.0"	"387.6"	"475.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14770"	"Homeobox protein Meis2 OS=Homo sapiens OX=9606 GN=MEIS2 PE=1 SV=2"	"3"	"1"	"2"	"1"	"477"	"51.8"	"6.40"	"477.14"	"4.92"	"1"	"1"	"developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05920, Pf16493"	"4212"	"ENSG00000134138"	"MEIS2"	"A6NJI5; A8MWD5; B3KP98; B3KPQ6; hsa:4212; O14770; Q96DI2; Q96KI4; Q96KI5; Q9NRS1; Q9NRS2; Q9NRS3"	""	""	"0"	"0"	"5.9"	"7.4"	"6.9"	"5.0"	"8.9"	"9.2"	"7.5"	"12.1"	"18.0"	"55.1"	"74.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16625"	"Occludin OS=Homo sapiens OX=9606 GN=OCLN PE=1 SV=1"	"2"	"1"	"2"	"1"	"522"	"59.1"	"6.09"	"327.63"	"4.92"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01284, Pf07303"	"100506658"	"ENSG00000197822"	"OCLN"	"B5BU70; D2DU64; D2DU65; D2IGC0; D2IGC1; E2CYV9; hsa:100506658; Q16625; Q5U1V4; Q8N6K1"	"Pathogenic Escherichia coli infection; VEGFA-VEGFR2 signaling; Epithelial to mesenchymal transition in colorectal cancer; 1q21.1 copy number variation syndrome; CKAP4 signaling pathway map; 15q11q13 copy number variation"	"RUNX1 regulates expression of components of tight junctions; Apoptotic cleavage of cell adhesion  proteins"	"8"	"0"	"62.0"	"54.4"	"74.1"	"66.2"	"78.6"	"73.0"	"86.6"	"117.5"	"206.3"	"451.2"	"718.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15013"	"Rho guanine nucleotide exchange factor 10 OS=Homo sapiens OX=9606 GN=ARHGEF10 PE=1 SV=4"	"1"	"1"	"2"	"1"	"1369"	"151.5"	"5.68"	"383.41"	"4.92"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton"	"enzyme regulator activity;cytoskeletal activity"	"Pf00621, Pf19056, Pf19057"	"9639"	"ENSG00000104728; ENSG00000274726"	"ARHGEF10"	"hsa:9639; O14665; O15013; Q2KHR8; Q68D55; Q8IWD9; Q8IY77"	""	"RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; NRAGE signals death through JNK; G alpha (12/13) signalling events; RHOB GTPase cycle"	"7"	"0"	"5.6"	"3.8"	"6.0"	"3.7"	"3.3"	"3.8"	"8.1"	"14.1"	"43.7"	"94.4"	"124.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P54578"	"Ubiquitin carboxyl-terminal hydrolase 14 OS=Homo sapiens OX=9606 GN=USP14 PE=1 SV=3"	"4"	"1"	"2"	"1"	"494"	"56.0"	"5.30"	"483.07"	"4.91"	"1"	"1"	"cell-cell signaling;protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00443"	"9097"	"ENSG00000101557"	"USP14"	"B7Z4N8; hsa:9097; J3QRZ5; P54578; Q53XY5"	""	"Ub-specific processing proteases; Regulation of NF-kappa B signaling"	"2"	"0"	"21.3"	"18.3"	"23.7"	"19.4"	"29.8"	"23.8"	"24.2"	"43.3"	"110.5"	"171.3"	"237.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NWU1"	"3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial OS=Homo sapiens OX=9606 GN=OXSM PE=1 SV=1"	"3"	"1"	"2"	"1"	"459"	"48.8"	"7.66"	"396.14"	"4.90"	"1"	"1"	"other metabolic processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf00109, Pf02801"	"54995"	"ENSG00000151093"	"OXSM"	"hsa:54995; Q9NWU1"	"Mitochondrial fatty acid synthesis pathway"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95613"	"Pericentrin OS=Homo sapiens OX=9606 GN=PCNT PE=1 SV=4"	"1"	"1"	"2"	"1"	"3336"	"377.8"	"5.55"	"581.45"	"4.88"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"cytosol;cytoskeleton"	"other molecular function"	"Pf10495"	"5116"	"ENSG00000160299"	"PCNT"	"hsa:5116; O43152; O95613; Q7Z7C9"	""	"Aggrephagy; Late endosomal microautophagy; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Chaperone Mediated Autophagy"	"10"	"0"	"19.4"	"18.5"	"25.9"	"15.5"	"20.4"	"21.6"	"22.5"	"32.7"	"72.0"	"133.3"	"193.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15005"	"Signal peptidase complex subunit 2 OS=Homo sapiens OX=9606 GN=SPCS2 PE=1 SV=3"	"8"	"1"	"2"	"1"	"226"	"25.0"	"8.47"	"612.76"	"4.86"	"1"	"1"	"protein metabolism;other metabolic processes;transport"	"other membranes;ER/Golgi"	""	"Pf06703"	"9789"	"ENSG00000118363"	"SPCS2"	"hsa:9789; Q15005; Q15507; Q3KQT0; Q641R4; Q6FG65; Q6IRX0; Q6P1P4; Q96HU9"	"15q25 copy number variation"	"SRP-dependent cotranslational protein targeting to membrane; Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1); Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP); Synthesis, secretion, and deacylation of Ghrelin"	"5"	"0"	"9.5"	"9.4"	"13.0"	"12.1"	"15.0"	"14.6"	"11.4"	"17.1"	"41.2"	"70.5"	"80.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12792"	"Twinfilin-1 OS=Homo sapiens OX=9606 GN=TWF1 PE=1 SV=3"	"4"	"2"	"3"	"1"	"350"	"40.3"	"6.96"	"240.93"	"4.86"	"1"	"2"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00241"	"5756"	"ENSG00000151239"	"TWF1"	"A8K5A8; B3KXS6; B4DLX9; hsa:5756; Q12792; Q59G07; Q5U0B1; Q6FHJ1; Q6FHL6; Q6NUK9; Q86XL6; Q8TCD3"	""	"Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; RHOBTB2 GTPase cycle"	"3"	"0"	"33.9"	"28.4"	"47.2"	"30.9"	"46.4"	"40.6"	"45.6"	"47.5"	"143.2"	"643.9"	"933.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96T88"	"E3 ubiquitin-protein ligase UHRF1 OS=Homo sapiens OX=9606 GN=UHRF1 PE=1 SV=1"	"2"	"1"	"2"	"1"	"793"	"89.8"	"7.56"	"369.84"	"4.85"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00240, Pf00628, Pf02182, Pf12148"	"29128"	"ENSG00000276043"	"UHRF1"	"A0JBR2; A8K024; B2RBA9; hsa:29128; Q2HIX7; Q8J022; Q96T88; Q9H6S6; Q9P115; Q9P1U7"	"Pathways affected in adenoid cystic carcinoma; Pleural mesothelioma"	"DNA methylation"	"3"	"0"	"22.5"	"20.2"	"29.0"	"19.7"	"22.5"	"30.4"	"27.2"	"33.3"	"49.3"	"94.4"	"102.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95433"	"Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1"	"9"	"3"	"4"	"3"	"338"	"38.3"	"5.53"	"518.25"	"4.85"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi"	"other molecular function"	"Pf08327, Pf09229"	"10598"	"ENSG00000100591"	"AHSA1"	"B2R9L2; B4DUR9; hsa:10598; O95433; Q96IL6; Q9P060"	"T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection"	""	"1"	"0"	"31.4"	"27.0"	"32.8"	"35.9"	"35.5"	"37.7"	"60.4"	"111.6"	"296.8"	"710.7"	"1394.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86UE8"	"Serine/threonine-protein kinase tousled-like 2 OS=Homo sapiens OX=9606 GN=TLK2 PE=1 SV=2"	"4"	"3"	"5"	"2"	"772"	"87.6"	"8.41"	"1145.62"	"4.82"	"3"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"11011"	"ENSG00000146872"	"TLK2"	"D3DU07; hsa:11011; Q86UE8; Q9UKI7; Q9Y4F7"	"miRNA regulation of DNA damage response; DNA damage response"	""	"2"	"1"	"73.4"	"67.3"	"70.8"	"62.2"	"77.7"	"85.6"	"91.9"	"131.4"	"303.5"	"768.6"	"1009.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14331"	"Protein FRG1 OS=Homo sapiens OX=9606 GN=FRG1 PE=1 SV=1"	"10"	"2"	"3"	"2"	"258"	"29.2"	"9.01"	"754.49"	"4.81"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus"	"cytoskeletal activity"	"Pf06229"	"2483"	"ENSG00000109536; ENSG00000275145; ENSG00000283153; ENSG00000283630"	"FRG1"	"A8K775; hsa:2483; Q14331"	""	""	"0"	"0"	"122.8"	"77.1"	"147.5"	"117.3"	"140.8"	"133.5"	"152.5"	"215.2"	"804.8"	"684.0"	"538.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BWJ5"	"Splicing factor 3B subunit 5 OS=Homo sapiens OX=9606 GN=SF3B5 PE=1 SV=1"	"17"	"1"	"3"	"1"	"86"	"10.1"	"6.35"	"759.79"	"4.80"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf07189"	"83443"	"ENSG00000169976"	"SF3B5"	"B2R568; hsa:83443; Q7RTV1; Q9BWJ5"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"3"	"0"	"110.1"	"97.3"	"121.0"	"113.3"	"134.2"	"124.8"	"146.3"	"162.8"	"219.3"	"384.4"	"727.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BUT1"	"3-hydroxybutyrate dehydrogenase type 2 OS=Homo sapiens OX=9606 GN=BDH2 PE=1 SV=2"	"11"	"3"	"4"	"2"	"245"	"26.7"	"7.65"	"619.09"	"4.80"	"2"	"2"	"other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf13561"	"56898"	"ENSG00000164039"	"BDH2"	"A8K295; B4DUF6; hsa:56898; Q503A0; Q6IA46; Q6UWD3; Q9BUT1; Q9H8S8; Q9NRX8"	""	"Synthesis of Ketone Bodies"	"1"	"0"	"131.9"	"134.4"	"140.9"	"130.3"	"127.6"	"139.0"	"168.0"	"226.6"	"415.2"	"1276.8"	"1986.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y6M9"	"NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 OS=Homo sapiens OX=9606 GN=NDUFB9 PE=1 SV=3"	"9"	"1"	"2"	"1"	"179"	"21.8"	"8.38"	"469.27"	"4.79"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity"	"Pf05347"	"4715"	"ENSG00000147684"	"NDUFB9"	"B2R8M6; hsa:4715; Q9UQE8; Q9Y6M9"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial immune response to SARS-CoV-2; Oxidative phosphorylation"	"Complex I biogenesis"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H4G0"	"Band 4.1-like protein 1 OS=Homo sapiens OX=9606 GN=EPB41L1 PE=1 SV=2"	"3"	"2"	"3"	"2"	"881"	"98.4"	"5.62"	"904.10"	"4.79"	"2"	"1"	"cell organization and biogenesis"	"plasma membrane;other membranes;cytosol;cytoskeleton"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf04382, Pf05902, Pf08736, Pf09379, Pf09380"	"2036"	"ENSG00000088367"	"EPB41L1"	"hsa:2036; O15046; Q4VXM6; Q4VXM7; Q4VXM8; Q4VXN4; Q6ZT61; Q8IUU7; Q96CV5; Q96L65; Q9H4G0"	"Splicing factor NOVA regulated synaptic proteins"	"Trafficking of AMPA receptors; Neurexins and neuroligins; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea"	"5"	"0"	"13.5"	"15.6"	"12.1"	"10.8"	"12.5"	"11.9"	"15.8"	"32.9"	"126.2"	"179.5"	"209.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z4G4"	"tRNA (guanine(10)-N2)-methyltransferase homolog OS=Homo sapiens OX=9606 GN=TRMT11 PE=1 SV=1"	"3"	"1"	"2"	"1"	"463"	"53.4"	"7.78"	"424.87"	"4.79"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01170"	"60487"	"ENSG00000066651"	"TRMT11"	"E1P570; hsa:60487; Q5JY11; Q6PGQ5; Q7Z4G4; Q9HC13"	""	"tRNA modification in the nucleus and cytosol"	"1"	"0"	"30.9"	"30.9"	"38.1"	"28.4"	"41.6"	"50.9"	"58.8"	"66.2"	"132.9"	"340.9"	"604.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5PRF9"	"Protein Smaug homolog 2 OS=Homo sapiens OX=9606 GN=SAMD4B PE=1 SV=1"	"2"	"1"	"2"	"1"	"694"	"75.4"	"6.83"	"463.52"	"4.77"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00536"	"55095"	"ENSG00000179134"	"SAMD4B"	"A5Z0M6; hsa:55095; Q5PRF9; Q6P194"	""	""	"0"	"0"	"3.7"	"2.0"	"3.5"	"3.8"	"2.9"	"5.2"	"7.4"	"5.9"	"25.7"	"53.9"	"68.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HAV4"	"Exportin-5 OS=Homo sapiens OX=9606 GN=XPO5 PE=1 SV=1"	"2"	"1"	"1"	"1"	"1204"	"136.2"	"5.80"	""	"4.77"	""	"1"	"RNA metabolism OR transcription;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf08389, Pf19273"	"57510"	"ENSG00000124571"	"XPO5"	"hsa:57510; Q5JTE6; Q96G48; Q96HN3; Q9BWM6; Q9BZV5; Q9H9M4; Q9HAV4; Q9NT89; Q9NW39; Q9ULC9"	"miRNA biogenesis; exRNA mechanism of action and biogenesis; Primary ovarian insufficiency"	"MicroRNA (miRNA) biogenesis"	"4"	"0"	"14.5"	"10.8"	"16.2"	"13.7"	"15.8"	"15.1"	"24.0"	"31.2"	"50.7"	"100.1"	"152.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IVL6"	"Prolyl 3-hydroxylase 3 OS=Homo sapiens OX=9606 GN=P3H3 PE=1 SV=1"	"3"	"1"	"2"	"1"	"736"	"81.8"	"6.32"	"473.69"	"4.75"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"ER/Golgi;other cell component"	"other molecular function"	"Pf13640"	"10536"	"ENSG00000110811"	"P3H3"	"hsa:10536; Q13512; Q15740; Q66K32; Q6NX61; Q7L2T1; Q8IVL6"	""	"Collagen biosynthesis and modifying enzymes"	"1"	"0"	"11.4"	"19.6"	"16.4"	"7.8"	"18.7"	"5.0"	"12.6"	"23.1"	"25.4"	"33.7"	"38.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H6R4"	"Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1146"	"127.5"	"7.64"	"620.62"	"4.75"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"mitochondrion;nucleus;other cell component"	""	"Pf03813, Pf17403, Pf17404, Pf17405, Pf17406, Pf17407"	"65083"	"ENSG00000165271"	"NOL6"	"hsa:65083; Q5T5M3; Q5T5M4; Q7L4G6; Q8N6I0; Q8TEY9; Q8TEZ0; Q8TEZ1; Q9H675; Q9H6R4"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"25.3"	"21.7"	"31.5"	"27.5"	"33.5"	"34.7"	"40.6"	"67.9"	"143.4"	"228.2"	"274.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96T23"	"Remodeling and spacing factor 1 OS=Homo sapiens OX=9606 GN=RSF1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1441"	"163.7"	"5.01"	"527.67"	"4.75"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00628, Pf15612"	"51773"	"ENSG00000048649"	"RSF1"	"hsa:51773; Q86X86; Q96T23; Q9H3L8; Q9NVZ8; Q9NYU0"	""	"Deposition of new CENPA-containing nucleosomes at the centromere"	"1"	"0"	"76.4"	"46.1"	"82.9"	"64.2"	"71.1"	"71.5"	"109.8"	"143.3"	"181.2"	"283.3"	"374.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TDN4"	"CDK5 and ABL1 enzyme substrate 1 OS=Homo sapiens OX=9606 GN=CABLES1 PE=1 SV=2"	"4"	"2"	"3"	"2"	"633"	"67.6"	"9.17"	"935.61"	"4.75"	"2"	"1"	"cell cycle OR cell proliferation;developmental processes;other biological processes"	"cytosol;nucleus"	""	"Pf00134"	"91768"	"ENSG00000134508"	"CABLES1"	"B4DK60; hsa:91768; Q8N3Y8; Q8NA22; Q8TDN4; Q9BTG1"	""	"Factors involved in megakaryocyte development and platelet production; Cyclin E associated events during G1/S transition ; Cyclin A:Cdk2-associated events at S phase entry"	"3"	"0"	"8.0"	"3.3"	"6.6"	"7.1"	"8.6"	"22.3"	"52.2"	"105.5"	"150.5"	"128.8"	"133.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P20674"	"Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A PE=1 SV=2"	"10"	"1"	"2"	"1"	"150"	"16.8"	"6.79"	"414.35"	"4.74"	"1"	"1"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf02284"	"9377"	"ENSG00000178741"	"COX5A"	"hsa:9377; P20674; P30045; Q8TB65"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex IV assembly; 5q35 copy number variation; Arachidonate epoxygenase / epoxide hydrolase"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"8"	"0"	"16.8"	"15.3"	"17.6"	"15.8"	"22.2"	"19.4"	"14.8"	"25.9"	"73.2"	"261.1"	"433.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P000"	"COMM domain-containing protein 9 OS=Homo sapiens OX=9606 GN=COMMD9 PE=1 SV=2"	"6"	"1"	"1"	"1"	"198"	"21.8"	"5.88"	""	"4.74"	""	"1"	"transport;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;nucleus;other cell component"	""	"Pf07258"	"29099"	"ENSG00000110442"	"COMMD9"	"E9PAN2; hsa:29099; Q96FI2; Q9H0R0; Q9P000"	""	"Neutrophil degranulation; Neddylation"	"2"	"0"	"24.2"	"19.2"	"30.7"	"29.0"	"26.7"	"22.4"	"24.2"	"40.4"	"76.0"	"224.4"	"492.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9C037"	"E3 ubiquitin-protein ligase TRIM4 OS=Homo sapiens OX=9606 GN=TRIM4 PE=1 SV=2"	"2"	"1"	"4"	"1"	"500"	"57.4"	"8.10"	""	"4.74"	""	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00622, Pf00643, Pf15227"	"89122"	"ENSG00000146833"	"TRIM4"	"A4D298; hsa:89122; Q75MK1; Q96F06; Q9C036; Q9C037"	""	"Antigen processing: Ubiquitination & Proteasome degradation; SARS-CoV-2 activates/modulates innate and adaptive immune responses; TRAF6 mediated NF-kB activation; NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10; Negative regulators of DDX58/IFIH1 signaling; Ovarian tumor domain proteases; TRAF3-dependent IRF activation pathway; TRAF6 mediated IRF7 activation"	"9"	"0"	"63.9"	"86.6"	"47.0"	"54.7"	"60.1"	"55.9"	"85.5"	"134.0"	"336.9"	"719.3"	"1077.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75380"	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS6 PE=1 SV=1"	"9"	"1"	"2"	"1"	"124"	"13.7"	"8.28"	"401.49"	"4.74"	"1"	"1"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf10276"	"4726"	"ENSG00000145494"	"NDUFS6"	"hsa:4726; O75380"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"76.8"	"93.7"	"66.8"	"61.9"	"82.8"	"84.7"	"109.1"	"127.3"	"279.6"	"477.1"	"646.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NZN8"	"CCR4-NOT transcription complex subunit 2 OS=Homo sapiens OX=9606 GN=CNOT2 PE=1 SV=1"	"3"	"1"	"2"	"1"	"540"	"59.7"	"7.66"	"634.29"	"4.74"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf04153"	"4848"	"ENSG00000111596"	"CNOT2"	"hsa:4848; Q9H3E0; Q9NSX5; Q9NWR6; Q9NZN8; Q9P028"	""	"Deadenylation of mRNA; TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"	"2"	"0"	"6.5"	"4.8"	"7.5"	"6.0"	"8.5"	"7.4"	"10.0"	"8.1"	"13.2"	"21.8"	"40.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NEF9"	"Serum response factor-binding protein 1 OS=Homo sapiens OX=9606 GN=SRFBP1 PE=1 SV=1"	"3"	"1"	"2"	"1"	"429"	"48.6"	"9.58"	"399.60"	"4.72"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf09073"	"153443"	"ENSG00000151304"	"SRFBP1"	"hsa:153443; Q5QFI2; Q8NEF9; Q96AH4; Q96DK2"	""	""	"0"	"0"	"39.4"	"45.4"	"42.8"	"36.7"	"47.9"	"49.9"	"54.8"	"48.5"	"71.0"	"199.5"	"262.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43402"	"ER membrane protein complex subunit 8 OS=Homo sapiens OX=9606 GN=EMC8 PE=1 SV=1"	"17"	"2"	"2"	"2"	"210"	"23.8"	"6.40"	"316.85"	"4.72"	"1"	"1"	"cell organization and biogenesis"	"other membranes;ER/Golgi;other cell component"	""	"Pf03665"	"10328"	"ENSG00000131148"	"EMC8"	"C9JB21; hsa:10328; O43402"	""	""	"0"	"0"	"52.4"	"66.8"	"60.6"	"52.7"	"62.7"	"59.0"	"82.8"	"108.4"	"232.4"	"449.5"	"630.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y371"	"Endophilin-B1 OS=Homo sapiens OX=9606 GN=SH3GLB1 PE=1 SV=1"	"9"	"2"	"2"	"2"	"365"	"40.8"	"6.04"	"436.02"	"4.72"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf03114, Pf14604"	"51100"	"ENSG00000097033"	"SH3GLB1"	"B4E182; hsa:51100; Q5H8U5; Q9H3Z0; Q9NR47; Q9NYA9; Q9Y371"	"Nanoparticle triggered autophagic cell death"	""	"1"	"0"	"24.1"	"23.0"	"23.2"	"21.7"	"26.1"	"23.7"	"24.3"	"39.7"	"82.7"	"258.3"	"413.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z4W1"	"L-xylulose reductase OS=Homo sapiens OX=9606 GN=DCXR PE=1 SV=2"	"7"	"2"	"3"	"2"	"244"	"25.9"	"8.10"	"344.06"	"4.72"	"1"	"2"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf13561"	"51181"	"ENSG00000169738"	"DCXR"	"hsa:51181; Q7Z4W1; Q9BTZ3; Q9UHY9"	""	"Formation of xylulose-5-phosphate; Essential pentosuria"	"2"	"0"	"232.5"	"232.4"	"267.1"	"228.6"	"251.3"	"269.2"	"294.8"	"364.1"	"654.2"	"1002.5"	"1255.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NRL2"	"Bromodomain adjacent to zinc finger domain protein 1A OS=Homo sapiens OX=9606 GN=BAZ1A PE=1 SV=2"	"2"	"3"	"5"	"3"	"1556"	"178.6"	"6.60"	"905.84"	"4.72"	"3"	"2"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00439, Pf00628, Pf02791, Pf10537, Pf15612, Pf15613"	"11177"	"ENSG00000198604"	"BAZ1A"	"hsa:11177; Q9NRL2; Q9NZ15; Q9P065; Q9UIG1; Q9Y3V3"	"Ectoderm differentiation"	""	"1"	"0"	"95.1"	"84.1"	"80.7"	"75.2"	"92.7"	"96.8"	"116.6"	"135.4"	"364.2"	"771.9"	"938.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IYJ1"	"Copine-9 OS=Homo sapiens OX=9606 GN=CPNE9 PE=1 SV=3"	"6"	"2"	"2"	"1"	"553"	"61.8"	"5.34"	"340.78"	"4.71"	"1"	"1"	"other biological processes"	"plasma membrane;other membranes"	"other molecular function"	"Pf00168, Pf07002"	"151835"	"ENSG00000144550"	"CPNE9"	"A1L430; A6NDX6; A8MSP8; hsa:151835; Q8IYJ1"	""	""	"0"	"0"	"6.3"	"4.1"	"8.8"	"4.2"	"3.9"	"5.8"	"4.0"	"11.6"	"24.8"	"57.9"	"84.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00471"	"Exocyst complex component 5 OS=Homo sapiens OX=9606 GN=EXOC5 PE=1 SV=1"	"2"	"1"	"2"	"1"	"708"	"81.8"	"6.71"	"578.16"	"4.71"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf07393"	"10640"	"ENSG00000070367"	"EXOC5"	"B2R6C5; hsa:10640; O00471; Q8IW24"	"Ciliary landscape"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"4"	"0"	"5.7"	"5.4"	"8.1"	"7.9"	"8.0"	"2.8"	"10.4"	"19.1"	"60.0"	"106.5"	"128.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92796"	"Disks large homolog 3 OS=Homo sapiens OX=9606 GN=DLG3 PE=1 SV=2"	"4"	"2"	"3"	"1"	"817"	"90.3"	"7.03"	"761.13"	"4.70"	"2"	"1"	"cell-cell signaling;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00018, Pf00595, Pf00625, Pf10600"	"1741"	"ENSG00000082458"	"DLG3"	"B4E0H1; D3DVU5; hsa:1741; Q5JUW6; Q5JUW7; Q92796; Q9ULI8"	""	"Assembly and cell surface presentation of NMDA receptors; RAF/MAP kinase cascade; Ras activation upon Ca2+ influx through NMDA receptor; Unblocking of NMDA receptors, glutamate binding and activation; Negative regulation of NMDA receptor-mediated neuronal transmission; Long-term potentiation; Neurexins and neuroligins; Synaptic adhesion-like molecules; NrCAM interactions; Activation of Ca-permeable Kainate Receptor"	"10"	"0"	"29.7"	"26.4"	"32.4"	"32.7"	"33.9"	"33.6"	"41.4"	"68.0"	"147.9"	"205.5"	"187.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UPQ9"	"Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens OX=9606 GN=TNRC6B PE=1 SV=4"	"1"	"1"	"1"	"1"	"1833"	"193.9"	"6.76"	""	"4.70"	""	"1"	"other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf10427, Pf16608"	"23112"	"ENSG00000100354"	"TNRC6B"	"B0QY73; B0QY78; B4DGC0; hsa:23112; Q5TH52; Q8TBX2; Q9UPQ9"	""	"Oxidative Stress Induced Senescence; MAPK6/MAPK4 signaling; Estrogen-dependent gene expression; Pre-NOTCH Transcription and Translation; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; TP53 Regulates Metabolic Genes; Oncogene Induced Senescence; Transcriptional Regulation by VENTX; Ca2+ pathway; Regulation of MECP2 expression and activity; NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux; Regulation of RUNX1 Expression and Activity; Regulation of CDH11 mRNA translation by microRNAs; Regulation of NPAS4 mRNA translation; Post-transcriptional silencing by small RNAs; Competing endogenous RNAs (ceRNAs) regulate PTEN translation"	"18"	"0"	"10.5"	"5.5"	"7.9"	"7.5"	"9.1"	"7.2"	"8.6"	"8.6"	"30.4"	"61.1"	"75.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q00796"	"Sorbitol dehydrogenase OS=Homo sapiens OX=9606 GN=SORD PE=1 SV=4"	"5"	"2"	"4"	"2"	"357"	"38.3"	"7.97"	"562.59"	"4.69"	"2"	"2"	"other metabolic processes;stress response;other biological processes"	"non-structural extracellular;other membranes;cytosol;cytoskeleton;mitochondrion"	"other molecular function"	"Pf00107, Pf08240"	"6652"	"ENSG00000140263"	"SORD"	"B2R655; B7Z3A6; hsa:6652; J3JZZ5; Q00796; Q16682; Q9UMD6"	"Disorders of fructose metabolism; Polyol pathway"	"Formation of xylulose-5-phosphate; Fructose biosynthesis"	"4"	"0"	"165.1"	"138.2"	"160.4"	"118.9"	"135.2"	"141.2"	"195.8"	"209.2"	"224.5"	"390.0"	"580.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IXM3"	"39S ribosomal protein L41, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL41 PE=1 SV=1"	"12"	"2"	"3"	"2"	"137"	"15.4"	"9.57"	"318.22"	"4.68"	"1"	"2"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus;other cell component"	"other molecular function"	"Pf09809"	"64975"	"ENSG00000182154"	"MRPL41"	"hsa:64975; Q8IXM3; Q96Q49"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"116.4"	"126.7"	"127.4"	"103.8"	"124.4"	"135.3"	"159.8"	"194.0"	"288.5"	"607.4"	"973.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q3B7T1"	"Erythroid differentiation-related factor 1 OS=Homo sapiens OX=9606 GN=EDRF1 PE=1 SV=1"	"2"	"2"	"4"	"2"	"1238"	"138.4"	"6.33"	"499.19"	"4.68"	"2"	"2"	"other biological processes"	"nucleus"	""	""	"26098"	"ENSG00000107938"	"EDRF1"	"B2RC65; hsa:26098; Q3B7T1; Q3KR40; Q4G190; Q5VZQ4; Q8IZ74; Q9Y3W4"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UL15"	"BAG family molecular chaperone regulator 5 OS=Homo sapiens OX=9606 GN=BAG5 PE=1 SV=1"	"4"	"2"	"3"	"1"	"447"	"51.2"	"6.05"	"267.94"	"4.68"	"1"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf02179"	"9529"	"ENSG00000166170"	"BAG5"	"hsa:9529; O94950; Q86W59; Q9UL15"	""	"Regulation of HSF1-mediated heat shock response"	"1"	"0"	"7.6"	"7.5"	"8.5"	"9.5"	"11.8"	"8.3"	"8.3"	"13.0"	"33.0"	"61.5"	"76.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95166"	"Gamma-aminobutyric acid receptor-associated protein OS=Homo sapiens OX=9606 GN=GABARAP PE=1 SV=1"	"25"	"2"	"3"	"1"	"117"	"13.9"	"8.79"	"858.17"	"4.67"	"2"	"1"	"cell-cell signaling;cell organization and biogenesis;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf02991"	"11337"	"ENSG00000170296"	"GABARAP"	"hsa:11337; O95166"	"2q37 copy number variation syndrome"	"Macroautophagy; TBC/RABGAPs"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BZL1"	"Ubiquitin-like protein 5 OS=Homo sapiens OX=9606 GN=UBL5 PE=1 SV=1"	"21"	"2"	"4"	"2"	"73"	"8.5"	"8.44"	"498.96"	"4.67"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf00240"	"59286"	"ENSG00000198258"	"UBL5"	"hsa:59286; Q2NL89; Q9BZL1"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"133.9"	"157.6"	"154.3"	"138.3"	"162.1"	"160.9"	"213.2"	"332.9"	"797.4"	"1844.6"	"3036.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51398"	"28S ribosomal protein S29, mitochondrial OS=Homo sapiens OX=9606 GN=DAP3 PE=1 SV=1"	"4"	"1"	"2"	"1"	"398"	"45.5"	"8.88"	"434.40"	"4.66"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf10236"	"7818"	"ENSG00000132676"	"DAP3"	"B4DP59; B4DY62; E7EM60; hsa:7818; P51398; Q13044; Q68CT7; Q96Q20"	"CKAP4 signaling pathway map"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"4"	"0"	"34.6"	"31.1"	"50.0"	"37.1"	"37.6"	"43.5"	"47.7"	"56.9"	"100.2"	"145.5"	"198.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51665"	"26S proteasome non-ATPase regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMD7 PE=1 SV=2"	"7"	"1"	"1"	"1"	"324"	"37.0"	"6.77"	""	"4.65"	""	"1"	"protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf01398, Pf13012"	"5713"	"ENSG00000103035"	"PSMD7"	"D3DWS9; hsa:5713; P51665; Q6PKI2; Q96E97"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Ciliary landscape; Alzheimer's disease"	"Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Neutrophil degranulation; Regulation of expression of SLITs and ROBOs; Degradation of GLI1 by the proteasome; Hedgehog 'on' state; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"65"	"0"	"20.8"	"17.6"	"23.4"	"26.7"	"23.1"	"28.4"	"29.0"	"37.9"	"62.8"	"127.2"	"177.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q53EL6"	"Programmed cell death protein 4 OS=Homo sapiens OX=9606 GN=PDCD4 PE=1 SV=2"	"3"	"1"	"2"	"1"	"469"	"51.7"	"5.21"	"411.20"	"4.65"	"1"	"1"	"developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf02847"	"27250"	"ENSG00000150593"	"PDCD4"	"B2RCV4; B5ME91; hsa:27250; O15501; Q53EL6; Q5VZS6; Q6PJI5; Q8TAR5; Q99834"	"Translation inhibitors in chronically activated PDGFRA cells; A network map of Macrophage-stimulating protein (MSP) signaling; Interferon type I signaling pathways"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	"4"	"0"	"6.4"	"11.3"	"9.9"	"8.6"	"10.4"	"8.2"	"13.2"	"15.9"	"36.9"	"122.1"	"232.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75616"	"GTPase Era, mitochondrial OS=Homo sapiens OX=9606 GN=ERAL1 PE=1 SV=2"	"4"	"1"	"2"	"1"	"437"	"48.3"	"8.84"	"460.56"	"4.63"	"1"	"1"	"cell organization and biogenesis"	"other membranes;cytosol;mitochondrion"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf01926"	"26284"	"ENSG00000132591"	"ERAL1"	"B3KN21; C9JEC6; hsa:26284; O75616; O75617; Q8WUY4; Q96LE2; Q96TC0"	"Primary ovarian insufficiency"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"4"	"0"	"18.7"	"34.2"	"24.8"	"19.6"	"26.1"	"37.2"	"34.2"	"42.5"	"71.2"	"111.8"	"119.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TCF1"	"AN1-type zinc finger protein 1 OS=Homo sapiens OX=9606 GN=ZFAND1 PE=1 SV=1"	"5"	"1"	"2"	"1"	"268"	"30.8"	"7.39"	"429.23"	"4.63"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"other cell component"	"other molecular function"	"Pf01428"	"79752"	"ENSG00000104231"	"ZFAND1"	"E5RIG0; E5RJ99; hsa:79752; Q658R7; Q6IA32; Q6PGQ6; Q8TCF1; Q9H810"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96HP4"	"Oxidoreductase NAD-binding domain-containing protein 1 OS=Homo sapiens OX=9606 GN=OXNAD1 PE=1 SV=1"	"6"	"1"	"2"	"1"	"312"	"34.8"	"8.37"	"499.23"	"4.63"	"1"	"1"	""	""	"other molecular function"	"Pf00175"	"92106"	"ENSG00000154814"	"OXNAD1"	"hsa:92106; Q2HYC7; Q59FA4; Q96HP4"	""	""	"0"	"0"	"9.6"	"6.9"	"10.9"	"7.6"	"12.5"	"8.3"	"13.4"	"33.8"	"82.8"	"122.0"	"140.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60232"	"Protein ZNRD2 OS=Homo sapiens OX=9606 GN=ZNRD2 PE=1 SV=1"	"9"	"1"	"1"	"1"	"199"	"21.5"	"5.24"	""	"4.61"	""	"1"	"cell cycle OR cell proliferation;other biological processes"	""	""	"Pf06677"	"10534"	"ENSG00000173465"	"ZNRD2"	"hsa:10534; O60232"	""	""	"0"	"0"	"53.1"	"59.1"	"72.1"	"55.6"	"70.0"	"27.2"	"66.2"	"96.4"	"132.5"	"160.9"	"205.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96QZ7"	"Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 OS=Homo sapiens OX=9606 GN=MAGI1 PE=1 SV=3"	"2"	"2"	"3"	"2"	"1491"	"164.5"	"7.58"	"648.04"	"4.61"	"2"	"1"	"cell adhesion;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00397, Pf00595, Pf00625, Pf16663, Pf16666"	"9223"	"ENSG00000151276; ENSG00000282956"	"MAGI1"	"A8K188; hsa:9223; O00309; O43863; O75085; Q96QZ7; Q96QZ8; Q96QZ9"	"Pathways affected in adenoid cystic carcinoma"	""	"1"	"0"	"95.3"	"116.0"	"121.8"	"103.6"	"119.3"	"112.5"	"107.5"	"152.5"	"278.3"	"553.9"	"726.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2Z0"	"Protein SGT1 homolog OS=Homo sapiens OX=9606 GN=SUGT1 PE=1 SV=3"	"6"	"1"	"1"	"1"	"365"	"41.0"	"5.16"	""	"4.61"	""	"1"	"cell cycle OR cell proliferation;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf04969, Pf05002"	"10910"	"ENSG00000165416"	"SUGT1"	"A2A303; hsa:10910; Q5JAK5; Q5TAM6; Q6VXY6; Q9Y2Z0"	"Nucleotide-binding oligomerization domain (NOD) pathway"	"The NLRP3 inflammasome; Purinergic signaling in leishmaniasis infection"	"3"	"0"	"13.7"	"11.1"	"16.0"	"15.2"	"16.4"	"12.9"	"15.9"	"16.3"	"25.7"	"32.9"	"36.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N4J0"	"Carnosine N-methyltransferase OS=Homo sapiens OX=9606 GN=CARNMT1 PE=1 SV=1"	"3"	"1"	"2"	"1"	"409"	"47.2"	"6.32"	"506.15"	"4.61"	"1"	"1"	"other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf07942"	"138199"	"ENSG00000156017"	"CARNMT1"	"hsa:138199; Q7Z383; Q8N4J0; Q8N7C5"	""	"Histidine catabolism"	"1"	"0"	"8.8"	"7.8"	"13.7"	"7.3"	"9.8"	"14.0"	"13.9"	"19.9"	"73.3"	"158.0"	"208.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKJ3"	"G patch domain-containing protein 8 OS=Homo sapiens OX=9606 GN=GPATCH8 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1502"	"164.1"	"8.66"	"438.81"	"4.60"	"1"	"1"	""	"nucleus"	"other molecular function"	"Pf01585, Pf12171"	"23131"	"ENSG00000186566"	"GPATCH8"	"B9EGP9; hsa:23131; O60300; Q8TB99; Q9UKJ3"	""	""	"0"	"0"	"58.1"	"60.0"	"75.2"	"69.5"	"77.3"	"67.2"	"90.3"	"102.9"	"132.6"	"233.4"	"267.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22830"	"Ferrochelatase, mitochondrial OS=Homo sapiens OX=9606 GN=FECH PE=1 SV=2"	"4"	"1"	"2"	"1"	"423"	"47.8"	"8.73"	"468.50"	"4.58"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"other membranes;mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00762"	"2235"	"ENSG00000066926"	"FECH"	"A8KA72; hsa:2235; P22830; Q8IXN1; Q8NAN0"	"Hemesynthesis defects and porphyrias; Heme biosynthesis"	"Heme biosynthesis"	"3"	"0"	"24.4"	"35.5"	"40.6"	"45.0"	"36.2"	"37.5"	"54.6"	"77.3"	"198.3"	"325.1"	"366.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P00403"	"Cytochrome c oxidase subunit 2 OS=Homo sapiens OX=9606 GN=MT-CO2 PE=1 SV=1"	"7"	"1"	"2"	"1"	"227"	"25.5"	"4.82"	"478.54"	"4.57"	"1"	"1"	"other metabolic processes;stress response;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00116, Pf02790"	"4513"	"ENSG00000198712"	"MT-CO2"	"hsa:4513; P00403; Q37526"	"Electron transport chain: OXPHOS system in mitochondria; Endothelin pathways; EGF/EGFR signaling pathway; Nonalcoholic fatty liver disease; Neuroinflammation; Mitochondrial complex IV assembly; CCL18 signaling pathway; 5q35 copy number variation"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"11"	"0"	"18.2"	"24.5"	"33.9"	"22.3"	"24.8"	"21.0"	"28.9"	"45.4"	"117.1"	"267.7"	"366.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q4V328"	"GRIP1-associated protein 1 OS=Homo sapiens OX=9606 GN=GRIPAP1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"841"	"95.9"	"5.11"	"422.69"	"4.57"	"1"	"1"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	""	"56850"	"ENSG00000068400"	"GRIPAP1"	"A6NL78; hsa:56850; Q3MJ75; Q4V327; Q4V328; Q4V330; Q5HYG1; Q6N046; Q96DH8; Q9NQ43; Q9ULQ3"	""	""	"0"	"0"	"19.0"	"23.1"	"23.7"	"19.1"	"22.4"	"24.4"	"30.0"	"40.9"	"148.1"	"357.6"	"508.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75794"	"Cell division cycle protein 123 homolog OS=Homo sapiens OX=9606 GN=CDC123 PE=1 SV=1"	"2"	"1"	"4"	"1"	"336"	"39.1"	"4.81"	"503.05"	"4.56"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"other cell component"	""	"Pf07065"	"8872"	"ENSG00000151465"	"CDC123"	"A8JZZ7; hsa:8872; O75794; Q14107; Q5T0L4; Q5T0L5; Q5T0L7; Q5T0L8; Q5T0L9"	""	""	"0"	"0"	"50.9"	"46.6"	"55.1"	"47.8"	"47.4"	"44.6"	"41.2"	"132.0"	"2486.5"	"2225.0"	"1506.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NQC8"	"Intraflagellar transport protein 46 homolog OS=Homo sapiens OX=9606 GN=IFT46 PE=1 SV=1"	"7"	"1"	"2"	"1"	"304"	"34.3"	"4.54"	"484.30"	"4.56"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"cytoskeleton;other cell component"	""	"Pf12317"	"56912"	"ENSG00000118096"	"IFT46"	"A8K0F6; hsa:56912; Q9H6V5; Q9NQC8"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein; Genes related to primary cilium development (based on CRISPR)"	"Intraflagellar transport"	"4"	"0"	"3.4"	"5.0"	"5.9"	"3.9"	"5.0"	"7.1"	"7.9"	"8.7"	"24.0"	"46.9"	"88.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13905"	"Rap guanine nucleotide exchange factor 1 OS=Homo sapiens OX=9606 GN=RAPGEF1 PE=1 SV=3"	"2"	"2"	"3"	"2"	"1077"	"120.5"	"5.92"	"283.52"	"4.55"	"1"	"2"	"developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00617, Pf00618"	"2889"	"ENSG00000107263"	"RAPGEF1"	"hsa:2889; Q13905; Q5JUE4; Q68DL3; Q8IV73"	"Integrin-mediated cell adhesion; Androgen receptor network in prostate cancer; B cell receptor signaling pathway; IL-3 signaling pathway; Focal adhesion; Hepatocyte growth factor receptor signaling; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Insulin signaling; Interferon type I signaling pathways"	"RAC3 GTPase cycle; Regulation of signaling by CBL; Downstream signal transduction; Erythropoietin activates RAS; Frs2-mediated activation; MET activates RAP1 and RAC1"	"16"	"0"	"8.1"	"7.9"	"5.1"	"8.7"	"7.7"	"5.7"	"10.7"	"22.0"	"96.9"	"211.8"	"306.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H098"	"Protein FAM107B OS=Homo sapiens OX=9606 GN=FAM107B PE=1 SV=1"	"10"	"1"	"2"	"1"	"131"	"15.5"	"8.29"	"345.61"	"4.54"	"1"	"1"	""	""	""	"Pf06625"	"83641"	"ENSG00000065809"	"FAM107B"	"A8K1P4; D3DRT2; hsa:83641; Q5T9K7; Q5T9K8; Q6ZSI4; Q9H098"	""	""	"0"	"0"	"22.6"	"23.1"	"26.6"	"26.0"	"29.8"	"29.1"	"36.9"	"37.8"	"96.5"	"184.6"	"262.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9ULU4"	"Protein kinase C-binding protein 1 OS=Homo sapiens OX=9606 GN=ZMYND8 PE=1 SV=2"	"2"	"1"	"1"	"1"	"1186"	"131.6"	"7.20"	""	"4.53"	""	"1"	"cell organization and biogenesis;DNA metabolism;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00439, Pf00855, Pf12064"	"23613"	"ENSG00000101040"	"ZMYND8"	"B3KVL2; B7Z2A8; B7Z3E0; B7Z680; B7ZM62; E1P5U5; F5H0X3; H7C0U2; hsa:23613; J3KPU3; Q13517; Q2HXV1; Q2HXV2; Q2HXV3; Q2HXV4; Q2HXV7; Q2HXV8; Q2HXV9; Q2HXW0; Q2HXW1; Q2HXW2; Q4JJ94; Q4JJ95; Q5TH09; Q5TH11; Q6MZM1; Q8WXC5; Q9H1F3; Q9H1F4; Q9H1F5; Q9H1L8; Q9H1L9; Q9H2G5; Q9NYN3; Q9UIX6; Q9ULU4"	""	""	"0"	"0"	"5.7"	"9.0"	"5.8"	"4.1"	"8.8"	"5.8"	"7.5"	"10.4"	"11.6"	"26.8"	"52.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NC56"	"LEM domain-containing protein 2 OS=Homo sapiens OX=9606 GN=LEMD2 PE=1 SV=1"	"3"	"1"	"2"	"1"	"503"	"56.9"	"9.00"	"386.93"	"4.53"	"1"	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"other membranes;cytoskeleton;nucleus;other cell component"	""	"Pf03020, Pf09402"	"221496"	"ENSG00000161904"	"LEMD2"	"B4DVH5; E7EVT2; hsa:221496; Q5T972; Q5T974; Q8NC56"	""	"Sealing of the nuclear envelope (NE) by ESCRT-III; Initiation of Nuclear Envelope (NE) Reformation; Depolymerization of the Nuclear Lamina"	"4"	"0"	"11.3"	"11.1"	"12.6"	"14.1"	"13.4"	"16.3"	"15.5"	"20.9"	"50.3"	"92.0"	"114.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NHY2"	"E3 ubiquitin-protein ligase COP1 OS=Homo sapiens OX=9606 GN=COP1 PE=1 SV=1"	"2"	"1"	"2"	"1"	"731"	"80.4"	"6.84"	"323.52"	"4.53"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00400, Pf13923"	"64326"	"ENSG00000143207"	"COP1"	"E9PKI0; hsa:64326; Q504W6; Q6H103; Q8NHY2; Q9H6L7; X5D9B4"	""	"Autodegradation of the E3 ubiquitin ligase COP1; Neddylation"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16763"	"Ubiquitin-conjugating enzyme E2 S OS=Homo sapiens OX=9606 GN=UBE2S PE=1 SV=2"	"7"	"1"	"2"	"1"	"222"	"23.8"	"8.38"	"507.79"	"4.52"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00179"	"27338"	"ENSG00000108106"	"UBE2S"	"hsa:27338; Q16763; Q9BTC1"	""	"Senescence-Associated Secretory Phenotype (SASP); Antigen processing: Ubiquitination & Proteasome degradation; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Separation of Sister Chromatids; CDK-mediated phosphorylation and removal of Cdc6; Autodegradation of Cdh1 by Cdh1:APC/C; Assembly of the pre-replicative complex; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of Cyclin B; Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase; Regulation of APC/C activators between G1/S and early anaphase; Phosphorylation of the APC/C; APC-Cdc20 mediated degradation of Nek2A; Transcriptional Regulation by VENTX; Aberrant regulation of mitotic exit in cancer due to RB1 defects; Synthesis of active ubiquitin: roles of E1 and E2 enzymes"	"19"	"0"	"17.5"	"16.5"	"23.7"	"18.9"	"16.6"	"25.8"	"30.5"	"42.9"	"100.4"	"199.0"	"182.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P53004"	"Biliverdin reductase A OS=Homo sapiens OX=9606 GN=BLVRA PE=1 SV=2"	"8"	"1"	"1"	"1"	"296"	"33.4"	"6.44"	""	"4.52"	""	"1"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf01408, Pf09166"	"644"	"ENSG00000106605"	"BLVRA"	"A8K747; hsa:644; O95019; P53004; Q86UX0; Q96QL4; Q9BRW8"	"IL-10 anti-inflammatory signaling pathway"	"Cytoprotection by HMOX1; Heme degradation"	"3"	"0"	"9.3"	"11.4"	"12.7"	"8.6"	"12.2"	"9.3"	"14.4"	"15.0"	"35.4"	"94.2"	"214.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55160"	"Nck-associated protein 1-like OS=Homo sapiens OX=9606 GN=NCKAP1L PE=1 SV=3"	"2"	"2"	"3"	"1"	"1127"	"128.1"	"6.86"	"240.65"	"4.50"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"enzyme regulator activity;other molecular function"	"Pf09735"	"3071"	"ENSG00000123338"	"NCKAP1L"	"B4DUT5; hsa:3071; P55160; Q52LW0"	"Microglia pathogen phagocytosis pathway; TYROBP causal network in microglia"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Neutrophil degranulation; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; VEGFA-VEGFR2 Pathway"	"10"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96ME7"	"Zinc finger protein 512 OS=Homo sapiens OX=9606 GN=ZNF512 PE=1 SV=2"	"3"	"1"	"2"	"1"	"567"	"64.6"	"9.76"	"650.17"	"4.50"	"1"	"1"	""	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00096"	"84450"	"ENSG00000243943"	"ZNF512"	"B4DSM5; hsa:84450; Q53RZ7; Q86XK6; Q96JM0; Q96ME7"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P84098"	"60S ribosomal protein L19 OS=Homo sapiens OX=9606 GN=RPL19 PE=1 SV=1"	"17"	"3"	"4"	"2"	"196"	"23.5"	"11.47"	"1089.40"	"4.50"	"3"	"1"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01280"	"6143"	"ENSG00000108298"	"RPL19"	"B2R4K2; hsa:6143; P14118; P22908; P84098; Q502Y6; Q7Z6E4"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"96.7"	"103.6"	"90.8"	"91.4"	"97.7"	"97.1"	"113.7"	"131.9"	"195.6"	"325.3"	"437.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5J1"	"U3 small nucleolar RNA-associated protein 18 homolog OS=Homo sapiens OX=9606 GN=UTP18 PE=1 SV=3"	"3"	"1"	"2"	"1"	"556"	"62.0"	"8.76"	"650.73"	"4.49"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;nucleus;other cell component"	""	""	"51096"	"ENSG00000011260"	"UTP18"	"hsa:51096; Q9H4N6; Q9Y5J1"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"64.1"	"77.3"	"75.9"	"60.8"	"61.2"	"68.3"	"88.6"	"87.7"	"106.7"	"165.5"	"218.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P2R7"	"Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLA2 PE=1 SV=3"	"3"	"1"	"2"	"1"	"463"	"50.3"	"7.42"	"504.89"	"4.48"	"1"	"1"	"other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf00549, Pf08442"	"8803"	"ENSG00000136143"	"SUCLA2"	"B2RDE7; hsa:8803; O95194; Q5T9Q4; Q5T9Q6; Q9NV21; Q9NVP7; Q9P2R7"	""	"Citric acid cycle (TCA cycle)"	"1"	"0"	"31.2"	"27.1"	"35.0"	"32.2"	"34.0"	"38.0"	"41.1"	"58.4"	"93.1"	"284.4"	"642.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NFJ9"	"Bardet-Biedl syndrome 1 protein OS=Homo sapiens OX=9606 GN=BBS1 PE=1 SV=1"	"3"	"1"	"2"	"1"	"593"	"65.0"	"7.93"	"354.68"	"4.48"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf14779"	"582"	"ENSG00000174483"	"BBS1"	"hsa:582; Q32MM9; Q32MN0; Q8NFJ9; Q96SN4"	"Ciliary landscape; Genes related to primary cilium development (based on CRISPR); Joubert syndrome; Ciliopathies; Bardet-Biedl syndrome"	"BBSome-mediated cargo-targeting to cilium"	"6"	"0"	"13.4"	"10.8"	"12.5"	"15.3"	"16.1"	"18.2"	"18.3"	"37.5"	"70.4"	"130.9"	"165.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IWC1"	"MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2"	"2"	"1"	"2"	"1"	"876"	"98.4"	"9.32"	"710.55"	"4.48"	"1"	"1"	"cell organization and biogenesis"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf05672"	"79649"	"ENSG00000129680"	"MAP7D3"	"A2A2J0; A6NCZ7; A6NHR4; B4DWD2; H7BY77; hsa:79649; Q5JXI5; Q5JXI6; Q6P2S1; Q8IWC1; Q9H9M8"	""	""	"0"	"0"	"97.7"	"72.8"	"92.4"	"86.4"	"107.6"	"100.2"	"110.5"	"117.3"	"187.2"	"200.9"	"209.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96QD9"	"UAP56-interacting factor OS=Homo sapiens OX=9606 GN=FYTTD1 PE=1 SV=3"	"4"	"1"	"2"	"1"	"318"	"35.8"	"11.78"	"394.92"	"4.47"	"1"	"1"	"other metabolic processes;transport"	"nucleus"	"nucleic acid binding activity"	"Pf07078"	"84248"	"ENSG00000122068"	"FYTTD1"	"A8MY74; B2RCB2; B7Z3R4; B7Z7V1; B7Z8I0; B7ZAJ3; C9J7P6; C9JNG6; C9JTH3; C9JY50; hsa:84248; Q96QD9; Q96SL9; Q9BQI8"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"3"	"0"	"47.7"	"50.6"	"66.4"	"44.6"	"54.2"	"56.7"	"71.4"	"69.7"	"99.0"	"177.8"	"304.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13674"	"Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2"	"4"	"2"	"3"	"2"	"534"	"61.0"	"6.01"	"745.85"	"4.47"	"2"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"ER/Golgi;other cell component"	"other molecular function"	"Pf08336, Pf13640"	"5033"	"ENSG00000122884"	"P4HA1"	"C9JL12; hsa:5033; P13674; Q15082; Q15083; Q5VSQ5"	"Type I collagen synthesis in the context of osteogenesis imperfecta"	"Collagen biosynthesis and modifying enzymes"	"2"	"0"	"56.3"	"63.5"	"75.5"	"46.8"	"59.9"	"71.6"	"80.6"	"119.9"	"157.9"	"283.4"	"428.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51571"	"Translocon-associated protein subunit delta OS=Homo sapiens OX=9606 GN=SSR4 PE=1 SV=1"	"7"	"1"	"2"	"1"	"173"	"19.0"	"6.15"	"338.45"	"4.47"	"1"	"1"	""	"other membranes;ER/Golgi;other cell component"	""	"Pf05404"	"6748"	"ENSG00000180879"	"SSR4"	"A8K378; hsa:6748; P51571; Q53XY1"	"VEGFA-VEGFR2 signaling"	"SRP-dependent cotranslational protein targeting to membrane"	"2"	"0"	"109.7"	"112.4"	"131.3"	"112.6"	"140.0"	"132.8"	"147.2"	"178.7"	"291.7"	"419.9"	"583.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01970"	"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 OS=Homo sapiens OX=9606 GN=PLCB3 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1234"	"138.7"	"5.90"	"502.80"	"4.47"	"1"	"1"	"other metabolic processes;transport;signal transduction;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00168, Pf00387, Pf00388, Pf08703, Pf09279, Pf17787"	"5331"	"ENSG00000149782"	"PLCB3"	"A5PKZ6; G5E960; hsa:5331; Q01970; Q8N1A4"	"Alzheimer's disease and miRNA effects; S1P receptor signal transduction; Myometrial relaxation and contraction pathways; G protein signaling pathways; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; GPR40 pathway; MAPK cascade; Wnt signaling; Non-genomic actions of 1,25 dihydroxyvitamin D3; Resistin as a regulator of inflammation; Hippo signaling regulation pathways; PKC-gamma calcium signaling pathway in ataxia; Kisspeptin/kisspeptin receptor system in the ovary; GPR143 in melanocytes and retinal pigment epithelium cells; Neuroinflammation and glutamatergic signaling; Alzheimer's disease; Calcium regulation in cardiac cells"	"G alpha (q) signalling events; Ca2+ pathway; G beta:gamma signalling through PLC beta; Presynaptic function of Kainate receptors; Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion; Synthesis of IP3 and IP4 in the cytosol; PLC beta mediated events; Acetylcholine regulates insulin secretion"	"26"	"0"	"27.4"	"23.7"	"31.8"	"31.6"	"27.8"	"23.3"	"41.8"	"42.1"	"75.7"	"114.2"	"144.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P2N5"	"RNA-binding protein 27 OS=Homo sapiens OX=9606 GN=RBM27 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1060"	"118.6"	"9.19"	"436.95"	"4.46"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf00076, Pf00642, Pf01480"	"54439"	"ENSG00000091009"	"RBM27"	"hsa:54439; Q8IYW9; Q9P2N5"	""	""	"0"	"0"	"40.5"	"40.9"	"39.7"	"43.0"	"49.4"	"38.0"	"43.3"	"63.4"	"161.2"	"329.4"	"437.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y262"	"Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1"	"3"	"1"	"2"	"1"	"564"	"66.7"	"6.34"	"453.24"	"4.45"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity"	"Pf10255"	"51386"	"ENSG00000100129"	"EIF3L"	"B2RDG6; B4DYB2; G8JLH4; hsa:51386; Q53HQ1; Q53HT4; Q5QTR1; Q5TI15; Q6ICD2; Q9Y262"	""	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition"	"6"	"0"	"19.8"	"15.3"	"33.9"	"22.0"	"24.4"	"21.4"	"26.6"	"30.9"	"79.0"	"168.3"	"479.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4B4"	"Helicase ARIP4 OS=Homo sapiens OX=9606 GN=RAD54L2 PE=1 SV=4"	"1"	"1"	"1"	"1"	"1467"	"162.7"	"6.09"	""	"4.45"	""	"1"	"cell organization and biogenesis"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271"	"23132"	"ENSG00000164080"	"RAD54L2"	"hsa:23132; Q8TB57; Q9BV54; Q9Y4B4"	"DYRK1A involvement regarding cell proliferation in brain development"	""	"1"	"0"	"10.0"	"9.4"	"8.3"	"9.0"	"12.1"	"9.0"	"8.3"	"11.8"	"19.4"	"25.2"	"34.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08574"	"Cytochrome c1, heme protein, mitochondrial OS=Homo sapiens OX=9606 GN=CYC1 PE=1 SV=3"	"7"	"1"	"1"	"1"	"325"	"35.4"	"9.00"	""	"4.45"	""	"1"	"other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf02167"	"1537"	"ENSG00000179091"	"CYC1"	"hsa:1537; P08574; Q5U062; Q6FHS7"	"Nonalcoholic fatty liver disease; Mitochondrial complex III assembly"	"Respiratory electron transport; Mitochondrial protein import"	"4"	"0"	"33.3"	"24.9"	"25.8"	"23.1"	"33.3"	"30.1"	"35.6"	"34.6"	"56.0"	"96.6"	"142.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95235"	"Kinesin-like protein KIF20A OS=Homo sapiens OX=9606 GN=KIF20A PE=1 SV=1"	"3"	"2"	"3"	"2"	"890"	"100.2"	"6.92"	"709.96"	"4.44"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"cytoskeleton;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225"	"10112"	"ENSG00000112984"	"KIF20A"	"B4DL79; D3DQB6; hsa:10112; O95235"	""	"COPI-dependent Golgi-to-ER retrograde traffic; MHC class II antigen presentation; Kinesins; Mitotic Telophase/Cytokinesis"	"4"	"0"	"30.3"	"31.5"	"36.9"	"29.1"	"34.2"	"28.8"	"39.2"	"52.3"	"78.1"	"125.2"	"181.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UFC0"	"Leucine-rich repeat and WD repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=LRWD1 PE=1 SV=2"	"2"	"2"	"4"	"2"	"647"	"70.8"	"7.21"	"523.21"	"4.44"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	""	"222229"	"ENSG00000161036"	"LRWD1"	"A8K4K2; B2R9G2; hsa:222229; Q8N0T9; Q8WV43; Q96GJ2; Q9UFC0"	"Male infertility"	""	"1"	"0"	"47.8"	"33.9"	"61.3"	"47.6"	"48.6"	"47.4"	"58.7"	"80.3"	"237.1"	"581.8"	"734.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TDR0"	"TRAF3-interacting protein 1 OS=Homo sapiens OX=9606 GN=TRAF3IP1 PE=1 SV=1"	"2"	"2"	"4"	"2"	"691"	"78.6"	"7.93"	"520.66"	"4.43"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf10243, Pf17749"	"26146"	"ENSG00000204104"	"TRAF3IP1"	"hsa:26146; Q6PCT1; Q7L8N9; Q8TDR0; Q9NRD6; Q9Y4Q1"	"Ciliary landscape; Genes related to primary cilium development (based on CRISPR); Ciliopathies; 2q37 copy number variation syndrome; Bardet-Biedl syndrome"	"Intraflagellar transport"	"6"	"0"	"98.7"	"94.0"	"116.2"	"100.4"	"115.3"	"115.4"	"136.0"	"170.7"	"345.2"	"644.3"	"768.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BXK1"	"Krueppel-like factor 16 OS=Homo sapiens OX=9606 GN=KLF16 PE=1 SV=1"	"7"	"1"	"2"	"1"	"252"	"25.4"	"9.88"	"639.91"	"4.43"	"1"	"1"	"signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00096"	"83855"	"ENSG00000129911"	"KLF16"	"hsa:83855; Q9BXK1"	""	""	"0"	"0"	"12.7"	"9.7"	"10.1"	"8.5"	"8.3"	"9.8"	"16.7"	"12.7"	"22.2"	"45.0"	"48.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P54727"	"UV excision repair protein RAD23 homolog B OS=Homo sapiens OX=9606 GN=RAD23B PE=1 SV=1"	"4"	"1"	"2"	"1"	"409"	"43.1"	"4.84"	"617.12"	"4.43"	"1"	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00240, Pf00627, Pf09280"	"5887"	"ENSG00000119318"	"RAD23B"	"B3KWK8; G5E9P0; hsa:5887; P54727; Q7Z5K8; Q8WUB0"	"Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"Formation of Incision Complex in GG-NER; Josephin domain DUBs; DNA Damage Recognition in GG-NER; N-glycan trimming in the ER and Calnexin/Calreticulin cycle"	"7"	"0"	"105.3"	"84.3"	"138.3"	"126.1"	"127.6"	"123.2"	"140.5"	"183.7"	"241.3"	"223.1"	"346.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86X10"	"Ral GTPase-activating protein subunit beta OS=Homo sapiens OX=9606 GN=RALGAPB PE=1 SV=1"	"1"	"1"	"2"	"1"	"1494"	"166.7"	"6.79"	"438.84"	"4.41"	"1"	"1"	"other biological processes"	""	"enzyme regulator activity;other molecular function"	"Pf20412"	"57148"	"ENSG00000170471"	"RALGAPB"	"A2A2E8; A2A2E9; hsa:57148; Q5TG31; Q86X10; Q8N3D1; Q8WWC0; Q9H3X8; Q9UJR1; Q9ULK1; Q9Y3G9"	""	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"	"1"	"0"	"15.9"	"14.6"	"17.4"	"13.7"	"24.6"	"16.1"	"31.0"	"70.2"	"154.1"	"215.5"	"249.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9GZN8"	"UPF0687 protein C20orf27 OS=Homo sapiens OX=9606 GN=C20orf27 PE=1 SV=3"	"8"	"1"	"2"	"1"	"174"	"19.3"	"6.84"	"418.30"	"4.41"	"1"	"1"	"other metabolic processes;other biological processes"	"non-structural extracellular"	"other molecular function"	"Pf15006"	"54976"	"ENSG00000101220"	"ADISSP"	"A8K4J0; D3DVX8; hsa:54976; Q5JX81; Q9GZN8; Q9NWX3"	""	""	"0"	"0"	"21.8"	"20.1"	"25.2"	"17.0"	"22.0"	"24.4"	"27.1"	"46.0"	"178.6"	"400.0"	"581.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5VVJ2"	"Histone H2A deubiquitinase MYSM1 OS=Homo sapiens OX=9606 GN=MYSM1 PE=1 SV=1"	"2"	"1"	"2"	"1"	"828"	"95.0"	"5.53"	"414.13"	"4.41"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00249, Pf01398, Pf04433"	"114803"	"ENSG00000162601"	"MYSM1"	"A8KA54; B3KX65; hsa:114803; Q5VVJ2; Q68DD3; Q6AI53; Q7Z3G8; Q96PX3"	""	"Metalloprotease DUBs"	"1"	"0"	"2.9"	"3.4"	"0.0"	"3.8"	"3.3"	"1.8"	"4.1"	"5.4"	"11.5"	"60.3"	"91.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60673"	"DNA polymerase zeta catalytic subunit OS=Homo sapiens OX=9606 GN=REV3L PE=1 SV=2"	"1"	"2"	"4"	"1"	"3130"	"352.6"	"8.47"	"559.77"	"4.41"	"2"	"2"	"DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00136, Pf03104, Pf14260, Pf15735"	"5980"	"ENSG00000009413"	"REV3L"	"hsa:5980; O43214; O60673; Q5TC33"	"DNA repair pathways, full network"	"Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96SK2"	"Transmembrane protein 209 OS=Homo sapiens OX=9606 GN=TMEM209 PE=1 SV=2"	"4"	"1"	"1"	"1"	"561"	"62.9"	"8.63"	""	"4.39"	""	"1"	""	"other membranes"	""	"Pf09786"	"84928"	"ENSG00000146842"	"TMEM209"	"A4D1L1; hsa:84928; Q49A50; Q6PF00; Q8NCH3; Q96SK2; Q96SL6"	""	""	"0"	"0"	"17.9"	"13.9"	"17.6"	"13.2"	"20.3"	"19.2"	"22.9"	"21.9"	"52.4"	"79.8"	"88.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14139"	"Ubiquitin conjugation factor E4 A OS=Homo sapiens OX=9606 GN=UBE4A PE=1 SV=2"	"1"	"1"	"2"	"1"	"1066"	"122.5"	"5.24"	"518.14"	"4.38"	"1"	"1"	"protein metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf04564, Pf10408"	"9354"	"ENSG00000110344"	"UBE4A"	"B0YJB6; hsa:9354; Q14139; Q2M1H0; Q6P5T4; Q7Z639"	""	"Antigen processing: Ubiquitination & Proteasome degradation"	"1"	"0"	"11.0"	"13.8"	"7.5"	"12.6"	"13.3"	"10.3"	"15.8"	"12.4"	"11.1"	"25.2"	"28.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NB78"	"Lysine-specific histone demethylase 1B OS=Homo sapiens OX=9606 GN=KDM1B PE=1 SV=3"	"1"	"1"	"2"	"1"	"822"	"92.0"	"7.87"	"417.03"	"4.38"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf01593, Pf04433, Pf07496"	"221656"	"ENSG00000165097"	"KDM1B"	"A2A2C5; A2A2C6; hsa:221656; Q5TGV3; Q6AI15; Q6ZUU4; Q8N258; Q8NB78; Q96EL7"	"Vitamin D-sensitive calcium signaling in depression"	"UCH proteinases; HDMs demethylate histones; NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"	"4"	"0"	"11.1"	"8.8"	"8.4"	"10.5"	"11.8"	"10.0"	"16.1"	"23.8"	"82.7"	"217.3"	"241.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09110"	"3-ketoacyl-CoA thiolase, peroxisomal OS=Homo sapiens OX=9606 GN=ACAA1 PE=1 SV=2"	"4"	"1"	"2"	"1"	"424"	"44.3"	"8.44"	"618.70"	"4.38"	"1"	"1"	"other metabolic processes"	"non-structural extracellular;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00108, Pf02803"	"30"	"ENSG00000060971"	"ACAA1"	"G5E935; hsa:30; P09110; Q96CA6"	"PPAR-alpha pathway; Nuclear receptors meta-pathway; Amino acid metabolism; PPAR signaling pathway; Eicosanoid metabolism via cyclooxygenases (COX); Eicosanoid metabolism via lipooxygenases (LOX)"	"Neutrophil degranulation; TYSND1 cleaves peroxisomal proteins; alpha-linolenic acid (ALA) metabolism; Beta-oxidation of very long chain fatty acids"	"11"	"0"	"44.2"	"32.4"	"42.1"	"46.5"	"33.2"	"40.1"	"46.5"	"52.7"	"112.9"	"233.5"	"367.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6DKJ4"	"Nucleoredoxin OS=Homo sapiens OX=9606 GN=NXN PE=1 SV=2"	"4"	"1"	"2"	"1"	"435"	"48.4"	"4.97"	"335.82"	"4.38"	"1"	"1"	"cell-cell signaling;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf13848, Pf13905"	"64359"	"ENSG00000167693"	"NXN"	"B4DXQ0; D3DTH2; hsa:64359; Q3SWW6; Q6DKJ4; Q6P3U6; Q7L4C6; Q9H9Q1"	""	""	"0"	"0"	"38.8"	"40.3"	"55.5"	"39.8"	"43.7"	"48.0"	"54.4"	"83.0"	"118.8"	"187.7"	"235.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15014"	"Mortality factor 4-like protein 2 OS=Homo sapiens OX=9606 GN=MORF4L2 PE=1 SV=1"	"6"	"1"	"2"	"1"	"288"	"32.3"	"9.72"	"519.68"	"4.37"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	""	"Pf05712"	"9643"	"ENSG00000123562"	"MORF4L2"	"B3KP92; D3DXA5; hsa:9643; Q15014; Q567V0; Q8J026"	""	"HATs acetylate histones"	"1"	"0"	"24.0"	"29.1"	"24.7"	"26.8"	"29.9"	"24.9"	"36.2"	"30.7"	"64.0"	"113.1"	"147.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NAV1"	"Pre-mRNA-splicing factor 38A OS=Homo sapiens OX=9606 GN=PRPF38A PE=1 SV=1"	"4"	"1"	"2"	"1"	"312"	"37.5"	"9.96"	"518.35"	"4.37"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf03371, Pf12871"	"84950"	"ENSG00000134748"	"PRPF38A"	"hsa:84950; Q8NAV1; Q96JW1; Q9BVZ8"	"MECP2 and associated Rett syndrome"	"mRNA Splicing - Major Pathway"	"2"	"0"	"29.4"	"21.9"	"43.1"	"34.2"	"43.4"	"75.4"	"137.8"	"164.5"	"364.0"	"441.8"	"700.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P53985"	"Monocarboxylate transporter 1 OS=Homo sapiens OX=9606 GN=SLC16A1 PE=1 SV=3"	"2"	"1"	"2"	"1"	"500"	"53.9"	"8.66"	"446.68"	"4.37"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"transporter activity;other molecular function"	"Pf07690"	"6566"	"ENSG00000155380; ENSG00000281917"	"SLC16A1"	"hsa:6566; P53985; Q49A45; Q5T8R6; Q9NSJ9"	"Photodynamic therapy-induced HIF-1 survival signaling; Fragile X syndrome; Glucose metabolism in triple-negative breast cancer cells"	"Pyruvate metabolism; Aspirin ADME; Basigin interactions; Proton-coupled monocarboxylate transport; Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT)"	"8"	"0"	"26.2"	"22.2"	"21.4"	"18.8"	"27.8"	"30.6"	"26.8"	"34.7"	"64.0"	"95.2"	"95.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75691"	"Small subunit processome component 20 homolog OS=Homo sapiens OX=9606 GN=UTP20 PE=1 SV=3"	"1"	"2"	"3"	"2"	"2785"	"318.2"	"7.39"	"266.59"	"4.36"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	""	"Pf07539, Pf20416"	"27340"	"ENSG00000120800"	"UTP20"	"hsa:27340; O75691; Q9H3H4"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"130.3"	"58.7"	"192.7"	"156.3"	"154.5"	"159.2"	"178.4"	"175.4"	"402.4"	"655.9"	"973.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86TI2"	"Dipeptidyl peptidase 9 OS=Homo sapiens OX=9606 GN=DPP9 PE=1 SV=3"	"3"	"1"	"1"	"1"	"863"	"98.2"	"6.46"	""	"4.36"	""	"1"	"protein metabolism;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00326, Pf00930, Pf19520"	"91039"	"ENSG00000142002"	"DPP9"	"hsa:91039; O75273; O75868; Q1ZZB8; Q6AI37; Q6UAL0; Q6ZMT2; Q6ZNJ5; Q86TI2; Q8N2J7; Q8N3F5; Q8WXD8; Q96NT8; Q9BVR3"	"Lung fibrosis"	""	"1"	"0"	"11.0"	"7.5"	"15.1"	"11.2"	"12.0"	"11.9"	"14.4"	"17.4"	"35.9"	"50.4"	"85.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5JTJ3"	"Cytochrome c oxidase assembly factor 6 homolog OS=Homo sapiens OX=9606 GN=COA6 PE=1 SV=1"	"11"	"1"	"2"	"1"	"125"	"14.1"	"8.25"	"343.99"	"4.34"	"1"	"1"	"cell organization and biogenesis;other metabolic processes"	"plasma membrane;other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf02297"	"388753"	"ENSG00000168275"	"COA6"	"hsa:388753; Q5JTJ2; Q5JTJ3; Q5JTJ4; Q8TA88"	"Mitochondrial complex IV assembly"	"Mitochondrial protein import"	"2"	"0"	"37.7"	"22.6"	"29.9"	"33.5"	"40.2"	"34.7"	"41.5"	"40.5"	"90.1"	"136.7"	"277.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35226"	"Polycomb complex protein BMI-1 OS=Homo sapiens OX=9606 GN=BMI1 PE=1 SV=2"	"6"	"2"	"2"	"1"	"326"	"36.9"	"8.63"	"240.71"	"4.33"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf13923, Pf16207"	"100532731; 648"	"ENSG00000168283"	"BMI1"	"hsa:100532731; hsa:648; P35226; Q16030; Q5T8Z3; Q96F37"	"Pleural mesothelioma; Interactions of natural killer cells in pancreatic cancer; CCL18 signaling pathway"	"Oxidative Stress Induced Senescence; SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6"	"12"	"1"	"69.8"	"83.7"	"80.1"	"74.9"	"79.2"	"76.8"	"87.6"	"159.5"	"560.5"	"1123.4"	"1388.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P53355"	"Death-associated protein kinase 1 OS=Homo sapiens OX=9606 GN=DAPK1 PE=1 SV=6"	"2"	"2"	"3"	"2"	"1430"	"159.9"	"6.83"	"962.32"	"4.33"	"2"	"1"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00023, Pf00069, Pf00531"	"1612"	"ENSG00000196730"	"DAPK1"	"B7ZLD2; B7ZLE7; hsa:1612; P53355; Q14CQ7; Q1W5W0; Q68CP8; Q6ZRZ3; Q9BTL8"	"Bladder cancer; Netrin-UNC5B signaling pathway"	"Caspase activation via Dependence Receptors in the absence of ligand"	"3"	"0"	"68.1"	"50.7"	"72.6"	"67.3"	"66.5"	"72.8"	"78.8"	"90.2"	"114.2"	"117.6"	"161.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P0U3"	"Sentrin-specific protease 1 OS=Homo sapiens OX=9606 GN=SENP1 PE=1 SV=2"	"3"	"1"	"2"	"1"	"644"	"73.4"	"8.47"	"385.33"	"4.33"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf02902"	"29843"	"ENSG00000079387"	"SENP1"	"A8K7P5; hsa:29843; Q86XC8; Q9P0U3"	""	"RHOF GTPase cycle; SUMO is proteolytically processed"	"2"	"0"	"24.1"	"27.4"	"29.9"	"21.3"	"23.5"	"28.1"	"36.8"	"39.5"	"64.1"	"126.9"	"206.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N196"	"Homeobox protein SIX5 OS=Homo sapiens OX=9606 GN=SIX5 PE=1 SV=3"	"3"	"1"	"1"	"1"	"739"	"74.5"	"4.96"	""	"4.33"	""	"1"	"cell cycle OR cell proliferation;developmental processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00046, Pf16878"	"147912"	"ENSG00000177045"	"SIX5"	"hsa:147912; Q8N196"	""	""	"0"	"0"	"7.5"	"8.1"	"12.4"	"8.9"	"7.1"	"7.9"	"5.4"	"16.7"	"25.6"	"37.0"	"45.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BRD0"	"BUD13 homolog OS=Homo sapiens OX=9606 GN=BUD13 PE=1 SV=1"	"2"	"1"	"2"	"1"	"619"	"70.5"	"9.86"	"494.56"	"4.33"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf09736"	"84811"	"ENSG00000137656"	"BUD13"	"A8K0S0; hsa:84811; Q96LS7; Q9BRD0"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"4.5"	"5.8"	"4.3"	"4.4"	"5.1"	"5.9"	"4.6"	"9.7"	"24.6"	"60.3"	"59.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14907"	"Tax1-binding protein 3 OS=Homo sapiens OX=9606 GN=TAX1BP3 PE=1 SV=2"	"14"	"1"	"2"	"1"	"124"	"13.7"	"8.48"	"392.44"	"4.32"	"1"	"1"	"cell-cell signaling;protein metabolism;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00595, Pf02163"	"30851"	"ENSG00000213977"	"TAX1BP3"	"B2RD53; D3DTJ6; hsa:30851; O14907; Q7LCQ4"	""	"RHO GTPases Activate Rhotekin and Rhophilins"	"1"	"0"	"21.1"	"17.3"	"27.6"	"22.6"	"24.6"	"26.7"	"28.8"	"46.5"	"141.1"	"330.8"	"605.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96Q83"	"Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 OS=Homo sapiens OX=9606 GN=ALKBH3 PE=1 SV=1"	"4"	"1"	"2"	"1"	"286"	"33.4"	"8.40"	"356.53"	"4.32"	"1"	"1"	"cell cycle OR cell proliferation;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf13532"	"221120"	"ENSG00000166199"	"ALKBH3"	"A6NDJ1; hsa:221120; Q3SYI0; Q6NX57; Q96BU8; Q96Q83"	"Direct reversal repair; 11p11.2 copy number variation syndrome"	"ALKBH3 mediated reversal of alkylation damage"	"3"	"0"	"31.6"	"23.5"	"29.6"	"29.2"	"33.1"	"32.8"	"42.0"	"40.9"	"75.8"	"128.0"	"218.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IYB5"	"Stromal membrane-associated protein 1 OS=Homo sapiens OX=9606 GN=SMAP1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"467"	"50.4"	"8.75"	"383.61"	"4.30"	"1"	"1"	"other biological processes"	"plasma membrane;other membranes;other cell component"	"enzyme regulator activity;other molecular function"	"Pf01412"	"60682"	"ENSG00000112305"	"SMAP1"	"hsa:60682; Q53H70; Q5SYQ2; Q6PK24; Q8IYB5; Q8NDH4; Q96L38; Q96L39; Q9H8X4"	""	""	"0"	"0"	"31.4"	"31.4"	"31.8"	"25.2"	"29.3"	"22.8"	"38.7"	"45.3"	"109.3"	"186.7"	"235.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z2Z2"	"Elongation factor-like GTPase 1 OS=Homo sapiens OX=9606 GN=EFL1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"1120"	"125.4"	"5.91"	"303.48"	"4.30"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00009, Pf00679, Pf14492"	"79631"	"ENSG00000140598"	"EFL1"	"A6NKY5; B7Z6I0; hsa:79631; Q7Z2Z2; Q9H8Z6"	"Genetic causes of porto-sinusoidal vascular disease"	""	"1"	"0"	"3.2"	"6.6"	"5.3"	"0.0"	"4.9"	"2.7"	"6.6"	"5.8"	"5.6"	"249.5"	"479.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99959"	"Plakophilin-2 OS=Homo sapiens OX=9606 GN=PKP2 PE=1 SV=2"	"2"	"2"	"3"	"1"	"881"	"97.4"	"9.33"	"281.53"	"4.29"	"1"	"2"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00514"	"5318"	"ENSG00000057294"	"PKP2"	"A0AV37; B8QFA1; B8QGS6; B8QGS7; D3DUW9; hsa:5318; Q4VC01; Q99959; Q99960"	"Arrhythmogenic right ventricular cardiomyopathy; Epithelial to mesenchymal transition in colorectal cancer"	"Formation of the cornified envelope"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EV8"	"Dysbindin OS=Homo sapiens OX=9606 GN=DTNBP1 PE=1 SV=1"	"4"	"1"	"2"	"1"	"351"	"39.5"	"4.67"	"403.61"	"4.29"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	""	"Pf04440"	"84062"	"ENSG00000047579"	"DTNBP1"	"A8K3V3; hsa:84062; Q5THY3; Q5THY4; Q96EV8; Q96NV2; Q9H0U2; Q9H3J5"	"Alstrom syndrome"	"Golgi Associated Vesicle Biogenesis"	"2"	"0"	"30.6"	"25.0"	"34.7"	"30.1"	"32.7"	"35.2"	"43.4"	"45.6"	"85.3"	"247.9"	"393.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P587"	"Acylpyruvase FAHD1, mitochondrial OS=Homo sapiens OX=9606 GN=FAHD1 PE=1 SV=2"	"6"	"1"	"2"	"1"	"224"	"24.8"	"7.39"	"426.17"	"4.27"	"1"	"1"	"other metabolic processes"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf01557"	"81889"	"ENSG00000180185"	"FAHD1"	"B1AK40; B1AK41; hsa:81889; Q6FIC7; Q6P587; Q96RY1; Q9H0N6"	""	"Citric acid cycle (TCA cycle)"	"1"	"0"	"16.1"	"11.0"	"14.1"	"16.8"	"19.9"	"14.6"	"20.7"	"35.5"	"166.3"	"375.7"	"635.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P015"	"39S ribosomal protein L15, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL15 PE=1 SV=1"	"4"	"1"	"2"	"1"	"296"	"33.4"	"10.01"	"495.43"	"4.25"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00828"	"29088"	"ENSG00000137547"	"MRPL15"	"hsa:29088; Q96Q54; Q9H0Y1; Q9P015"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"163.3"	"127.2"	"160.1"	"140.6"	"162.4"	"165.5"	"183.6"	"214.6"	"295.2"	"543.1"	"1079.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q3V6T2"	"Girdin OS=Homo sapiens OX=9606 GN=CCDC88A PE=1 SV=2"	"1"	"1"	"2"	"1"	"1871"	"215.9"	"6.21"	"336.38"	"4.25"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf19047"	"55704"	"ENSG00000115355"	"CCDC88A"	"A1IGE7; B7ZM78; C9JG83; hsa:55704; Q3V6T2; Q53SF1; Q581G3; Q5HYD0; Q7Z339; Q7Z3C5"	"Mesodermal commitment pathway"	"RND3 GTPase cycle; RND1 GTPase cycle"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23368"	"NAD-dependent malic enzyme, mitochondrial OS=Homo sapiens OX=9606 GN=ME2 PE=1 SV=1"	"3"	"1"	"2"	"1"	"584"	"65.4"	"7.61"	"321.77"	"4.24"	"1"	"1"	"other metabolic processes;other biological processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf00390, Pf03949"	"4200"	"ENSG00000082212"	"ME2"	"B2R8J2; hsa:4200; P23368; Q9BWL6; Q9BYG1; Q9H4B2"	"TCA cycle in senescence"	"Citric acid cycle (TCA cycle)"	"2"	"0"	"19.8"	"20.6"	"23.7"	"26.5"	"22.0"	"23.9"	"31.5"	"40.9"	"82.3"	"153.2"	"237.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q08J23"	"RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2"	"3"	"1"	"1"	"1"	"767"	"86.4"	"6.77"	""	"4.24"	""	"1"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytoskeleton;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01189"	"54888"	"ENSG00000037474"	"NSUN2"	"A8K529; B2RNR4; B3KP09; B4DQW2; G3V1R4; hsa:54888; Q08J23; Q9BVN4; Q9H858; Q9NXD9"	""	"tRNA modification in the nucleus and cytosol"	"1"	"0"	"11.9"	"8.1"	"11.4"	"11.3"	"11.2"	"14.2"	"17.1"	"15.1"	"27.9"	"58.3"	"74.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UK59"	"Lariat debranching enzyme OS=Homo sapiens OX=9606 GN=DBR1 PE=1 SV=2"	"3"	"1"	"1"	"1"	"544"	"61.5"	"5.47"	""	"4.24"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00149, Pf05011"	"51163"	"ENSG00000138231"	"DBR1"	"hsa:51163; Q96GH0; Q9NXQ6; Q9UK59"	""	""	"0"	"0"	"5.8"	"7.0"	"8.1"	"9.5"	"7.5"	"6.3"	"9.2"	"12.1"	"19.2"	"49.9"	"79.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q06210"	"Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3"	"3"	"2"	"3"	"2"	"699"	"78.8"	"7.11"	"785.18"	"4.23"	"2"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol"	"other molecular function"	"Pf01380, Pf13522"	"2673"	"ENSG00000198380"	"GFPT1"	"hsa:2673; Q06210; Q53QE6; Q9BXF8"	"UDP-derived sugars synthesis in fibroblasts"	"XBP1(S) activates chaperone genes; Synthesis of UDP-N-acetyl-glucosamine; Defective GFPT1 causes CMSTA1"	"4"	"0"	"16.6"	"13.5"	"24.4"	"22.0"	"18.0"	"19.1"	"20.6"	"34.2"	"96.3"	"224.2"	"276.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A8MVJ9"	"Putative histone PARylation factor 1-like OS=Homo sapiens OX=9606 PE=5 SV=1"	"3"	"1"	"2"	"1"	"347"	"39.7"	"8.10"	"524.53"	"4.23"	"1"	"1"	"stress response;other biological processes"	"nucleus"	"other molecular function"	"Pf10228"	""	""	""	""	""	""	"0"	"0"	"39.9"	"38.8"	"47.5"	"46.5"	"50.7"	"54.0"	"59.9"	"92.1"	"377.2"	"1125.9"	"1753.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96LT9"	"RNA-binding region-containing protein 3 OS=Homo sapiens OX=9606 GN=RNPC3 PE=1 SV=1"	"3"	"1"	"2"	"1"	"517"	"58.5"	"7.72"	"491.83"	"4.23"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076"	"55599"	"ENSG00000185946"	"RNPC3"	"A8K1C9; D3DT74; hsa:55599; Q5TZ87; Q96FK7; Q96JI8; Q96LT9; Q9NSU7; Q9NXX2"	""	"mRNA Splicing - Minor Pathway"	"1"	"0"	"19.9"	"10.1"	"13.9"	"13.2"	"16.3"	"12.8"	"24.6"	"22.9"	"36.3"	"62.0"	"93.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3X0"	"Coiled-coil domain-containing protein 9 OS=Homo sapiens OX=9606 GN=CCDC9 PE=1 SV=1"	"3"	"1"	"2"	"1"	"531"	"59.7"	"5.40"	"615.16"	"4.22"	"1"	"1"	""	"nucleus"	"nucleic acid binding activity"	"Pf15266"	"26093"	"ENSG00000105321"	"CCDC9"	"hsa:26093; Q9Y3X0"	"IL-18 signaling pathway"	""	"1"	"0"	"4.7"	"3.6"	"5.8"	"4.1"	"7.0"	"9.0"	"4.7"	"5.9"	"11.7"	"29.5"	"27.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62070"	"Ras-related protein R-Ras2 OS=Homo sapiens OX=9606 GN=RRAS2 PE=1 SV=1"	"6"	"1"	"2"	"1"	"204"	"23.4"	"6.01"	"401.18"	"4.22"	"1"	"1"	"developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi"	"other molecular function"	"Pf00071"	"22800"	"ENSG00000133818"	"RRAS2"	"B2R9Z3; B7Z5Z2; B7Z6C4; B7Z7H6; hsa:22800; P17082; P62070"	"MAPK signaling pathway; Ras signaling; Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells; EGFR tyrosine kinase inhibitor resistance; Regulation of actin cytoskeleton"	"RND1 GTPase cycle"	"6"	"0"	"10.2"	"12.2"	"14.0"	"16.0"	"18.3"	"15.2"	"17.7"	"25.4"	"53.9"	"121.0"	"149.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BV81"	"ER membrane protein complex subunit 6 OS=Homo sapiens OX=9606 GN=EMC6 PE=1 SV=1"	"12"	"1"	"2"	"1"	"110"	"12.0"	"10.07"	"426.98"	"4.22"	"1"	"1"	"cell organization and biogenesis;other metabolic processes"	"other membranes;ER/Golgi"	""	"Pf07019"	"83460"	"ENSG00000127774"	"EMC6"	"hsa:83460; Q9BV81"	""	""	"0"	"0"	"6.5"	"5.5"	"3.3"	"5.1"	"7.1"	"6.3"	"6.8"	"9.9"	"21.6"	"41.4"	"48.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y232"	"Chromodomain Y-like protein OS=Homo sapiens OX=9606 GN=CDYL PE=1 SV=2"	"2"	"1"	"2"	"1"	"598"	"66.4"	"9.45"	"367.78"	"4.22"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00378, Pf00385"	"9425"	"ENSG00000153046"	"CDYL"	"A8K6D6; B4DLG4; hsa:9425; Q0VDG7; Q32NC5; Q5VX99; Q6P7T5; Q9BWZ2; Q9Y232; Q9Y424"	""	""	"0"	"0"	"23.5"	"23.5"	"33.2"	"21.6"	"37.2"	"27.7"	"28.7"	"44.8"	"87.9"	"184.7"	"231.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60900"	"Proteasome subunit alpha type-6 OS=Homo sapiens OX=9606 GN=PSMA6 PE=1 SV=1"	"5"	"1"	"2"	"1"	"246"	"27.4"	"6.76"	"323.09"	"4.21"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00227, Pf10584"	"5687"	"ENSG00000100902"	"PSMA6"	"B2R7J9; B4DQR4; B4DXJ9; hsa:5687; P34062; P60900; Q6IB60"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Separation of Sister Chromatids; Downstream TCR signaling; FCERI mediated NF-kB activation; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"62"	"0"	"16.1"	"28.7"	"13.0"	"17.0"	"17.0"	"13.4"	"24.7"	"46.0"	"59.6"	"169.9"	"407.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P53999"	"Activated RNA polymerase II transcriptional coactivator p15 OS=Homo sapiens OX=9606 GN=SUB1 PE=1 SV=3"	"10"	"1"	"2"	"1"	"127"	"14.4"	"9.60"	"386.41"	"4.21"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02229"	"10923"	"ENSG00000113387"	"SUB1"	"hsa:10923; P53999; Q96L29"	""	""	"0"	"0"	"60.4"	"73.7"	"75.5"	"66.3"	"68.1"	"85.6"	"97.5"	"100.5"	"169.4"	"318.1"	"704.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z4S6"	"Kinesin-like protein KIF21A OS=Homo sapiens OX=9606 GN=KIF21A PE=1 SV=2"	"1"	"1"	"1"	"1"	"1674"	"187.1"	"6.42"	""	"4.21"	""	"1"	"other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225, Pf00400"	"55605"	"ENSG00000139116"	"KIF21A"	"A8MX28; B0I1R9; B9EGE4; F5H0C3; F5H219; hsa:55605; Q2UVF1; Q6UKL9; Q7Z4S6; Q7Z668; Q86WZ5; Q8IVZ8; Q9C0F5; Q9NXU4; Q9Y590"	""	"COPI-dependent Golgi-to-ER retrograde traffic; Kinesins"	"2"	"0"	"20.6"	"17.1"	"28.2"	"16.3"	"25.8"	"26.5"	"20.8"	"25.3"	"186.3"	"386.5"	"485.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96BJ3"	"Axin interactor, dorsalization-associated protein OS=Homo sapiens OX=9606 GN=AIDA PE=1 SV=1"	"6"	"1"	"2"	"1"	"306"	"35.0"	"6.55"	"407.05"	"4.21"	"1"	"1"	"developmental processes;other biological processes"	"other membranes;other cell component"	"other molecular function"	"Pf08910, Pf14186"	"64853"	"ENSG00000186063"	"AIDA"	"A8K1F0; hsa:64853; Q49A81; Q5JRA4; Q658P1; Q96BJ3; Q9H9E8"	""	""	"0"	"0"	"18.5"	"24.6"	"17.0"	"18.2"	"14.6"	"18.6"	"18.2"	"26.7"	"154.2"	"109.5"	"96.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5T280"	"Putative methyltransferase C9orf114 OS=Homo sapiens OX=9606 GN=SPOUT1 PE=1 SV=3"	"3"	"1"	"2"	"1"	"376"	"42.0"	"7.43"	"441.68"	"4.20"	"1"	"1"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02598"	"51490"	"ENSG00000198917"	"SPOUT1"	"hsa:51490; Q0D2P6; Q5T280; Q6P469; Q6PGP9; Q6PIJ1; Q6PJV9"	""	""	"0"	"0"	"93.7"	"84.1"	"115.0"	"109.6"	"117.8"	"99.7"	"119.6"	"116.0"	"205.4"	"278.5"	"315.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P48634"	"Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3"	"2"	"3"	"4"	"3"	"2157"	"228.7"	"9.45"	"1450.26"	"4.19"	"3"	"1"	"other biological processes"	"plasma membrane;other membranes;cytosol;nucleus"	""	"Pf07001"	"7916"	"ENSG00000204469; ENSG00000206427; ENSG00000225164; ENSG00000225748; ENSG00000226618; ENSG00000231370; ENSG00000231825"	"PRRC2A"	"B0UX77; B0UZE9; B0UZL3; hsa:7916; O95875; P48634; Q05BK4; Q4LE37; Q5SQ29; Q5SQ30; Q5ST84; Q5STX6; Q5STX7; Q68DW9; Q6P9P7; Q6PIN1; Q8MGQ9; Q96QC6"	""	""	"0"	"0"	"243.5"	"195.1"	"219.7"	"221.6"	"221.3"	"231.7"	"272.9"	"308.2"	"354.5"	"460.7"	"626.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04181"	"Ornithine aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OAT PE=1 SV=1"	"5"	"1"	"1"	"1"	"439"	"48.5"	"7.03"	""	"4.19"	""	"1"	"other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00202"	"4942"	"ENSG00000065154"	"OAT"	"D3DRF0; hsa:4942; P04181; Q16068; Q16069; Q68CS0; Q6IAV9; Q9UD03"	"Amino acid metabolism; 22q11.2 copy number variation syndrome; Creatine pathway"	"Glutamate and glutamine metabolism"	"4"	"0"	"14.2"	"17.5"	"24.4"	"22.7"	"16.4"	"8.1"	"23.2"	"47.0"	"55.3"	"116.2"	"200.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P17858"	"ATP-dependent 6-phosphofructokinase, liver type OS=Homo sapiens OX=9606 GN=PFKL PE=1 SV=6"	"1"	"1"	"2"	"1"	"780"	"85.0"	"7.50"	"387.99"	"4.19"	"1"	"1"	"other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00365"	"5211"	"ENSG00000141959"	"PFKL"	"hsa:5211; P17858; Q96A64; Q96IH4; Q9BR91"	"Photodynamic therapy-induced HIF-1 survival signaling; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Insulin signaling; Disorders of fructose metabolism; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"Neutrophil degranulation; Glycolysis"	"9"	"0"	"30.3"	"31.8"	"32.9"	"34.6"	"37.1"	"42.4"	"44.3"	"53.6"	"107.9"	"162.0"	"168.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92734"	"Protein TFG OS=Homo sapiens OX=9606 GN=TFG PE=1 SV=2"	"4"	"1"	"2"	"1"	"400"	"43.4"	"5.10"	"526.73"	"4.18"	"1"	"1"	"cell organization and biogenesis;transport"	"cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00564"	"10342"	"ENSG00000114354"	"TFG"	"D3DN49; G5E9V1; hsa:10342; K0J5S8; K0J6K2; Q15656; Q92734; Q969I2"	""	"Signaling by ALK fusions and activated point mutants; COPII-mediated vesicle transport"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N5A5"	"Zinc finger CCCH-type with G patch domain-containing protein OS=Homo sapiens OX=9606 GN=ZGPAT PE=1 SV=3"	"2"	"1"	"2"	"1"	"531"	"57.3"	"5.43"	"543.27"	"4.18"	"1"	"1"	"other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01585, Pf18044"	"84619"	"ENSG00000197114"	"ZGPAT"	"E1P5K1; hsa:84619; Q4VXN9; Q5JWI9; Q5JWJ0; Q8N5A5; Q8NC55; Q8WUV4; Q96JI0; Q96JU4; Q9H401"	""	""	"0"	"0"	"72.9"	"54.8"	"96.7"	"73.9"	"80.0"	"51.5"	"103.5"	"120.2"	"169.3"	"243.6"	"309.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13042"	"Cell division cycle protein 16 homolog OS=Homo sapiens OX=9606 GN=CDC16 PE=1 SV=2"	"3"	"1"	"2"	"1"	"620"	"71.6"	"5.85"	"359.62"	"4.17"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	""	"Pf12895, Pf13424"	"8881"	"ENSG00000130177"	"CDC16"	"A2A365; hsa:8881; Q13042; Q5T8C8; Q7Z651; Q96AE6; Q9Y564"	"Cell cycle"	"Senescence-Associated Secretory Phenotype (SASP); Antigen processing: Ubiquitination & Proteasome degradation; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Separation of Sister Chromatids; CDK-mediated phosphorylation and removal of Cdc6; Autodegradation of Cdh1 by Cdh1:APC/C; Assembly of the pre-replicative complex; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of Cyclin B; Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase; Regulation of APC/C activators between G1/S and early anaphase; Phosphorylation of the APC/C; APC-Cdc20 mediated degradation of Nek2A; Transcriptional Regulation by VENTX; Aberrant regulation of mitotic exit in cancer due to RB1 defects"	"19"	"0"	"30.7"	"20.8"	"37.8"	"31.6"	"32.8"	"35.5"	"38.6"	"54.3"	"114.2"	"202.3"	"263.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z2E3"	"Aprataxin OS=Homo sapiens OX=9606 GN=APTX PE=1 SV=2"	"4"	"1"	"2"	"1"	"356"	"40.7"	"9.17"	"445.19"	"4.15"	"1"	"1"	"DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf11969, Pf16278, Pf17913"	"54840"	"ENSG00000137074"	"APTX"	"A8MTN4; D3DRK9; D3DRL0; hsa:54840; Q0P662; Q5T781; Q5T782; Q5T784; Q6JV81; Q6JV82; Q6JV85; Q7Z2E3; Q7Z2F3; Q7Z336; Q7Z5R5; Q7Z6V7; Q7Z6V8; Q9NXM5"	""	""	"0"	"0"	"39.8"	"33.4"	"40.5"	"41.4"	"40.4"	"41.6"	"56.6"	"71.6"	"201.0"	"382.9"	"533.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6T4R5"	"Nance-Horan syndrome protein OS=Homo sapiens OX=9606 GN=NHS PE=1 SV=2"	"1"	"1"	"2"	"1"	"1651"	"179.0"	"6.86"	"421.94"	"4.15"	"1"	"1"	"developmental processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus;other cell component"	""	"Pf15273"	"4810"	"ENSG00000188158"	"NHS"	"B7ZVX8; E2DH69; hsa:4810; Q5J7Q0; Q5J7Q1; Q68DR5; Q6T4R5"	""	"RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UH03"	"Neuronal-specific septin-3 OS=Homo sapiens OX=9606 GN=SEPTIN3 PE=1 SV=3"	"7"	"1"	"1"	"1"	"358"	"40.7"	"7.20"	""	"4.15"	""	"1"	"cell cycle OR cell proliferation"	"cytoskeleton;other cell component"	"other molecular function"	"Pf00735"	"55964"	"ENSG00000100167"	"SEPTIN3"	"B1AHR0; hsa:55964; Q2NKJ7; Q59GF7; Q6IBZ6; Q8N3P3; Q9HD35; Q9UH03"	""	""	"0"	"0"	"10.3"	"5.3"	"12.3"	"12.4"	"12.8"	"8.0"	"12.2"	"21.4"	"56.0"	"82.6"	"105.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BYD6"	"39S ribosomal protein L1, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL1 PE=1 SV=2"	"9"	"3"	"5"	"3"	"325"	"36.9"	"8.78"	"1413.94"	"4.13"	"3"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00687"	"65008"	"ENSG00000169288"	"MRPL1"	"A6NG03; hsa:65008; Q4W5B8; Q6IAG4; Q96BW3; Q9BYD6; Q9H793; Q9NRL5"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"251.0"	"216.9"	"279.9"	"214.1"	"247.6"	"317.4"	"407.9"	"1170.9"	"3436.8"	"3328.1"	"3468.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35227"	"Polycomb group RING finger protein 2 OS=Homo sapiens OX=9606 GN=PCGF2 PE=1 SV=1"	"6"	"2"	"3"	"1"	"344"	"37.8"	"7.96"	"539.60"	"4.12"	"2"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13923, Pf16207"	"7703"	"ENSG00000277258; ENSG00000278644"	"PCGF2"	"A6NGD8; hsa:7703; P35227"	"17q12 copy number variation syndrome"	"SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; Transcriptional Regulation by E2F6; Activation of anterior HOX genes in hindbrain development during early embryogenesis"	"8"	"0"	"5.3"	"0.0"	"0.0"	"5.1"	"5.3"	"2.7"	"7.3"	"2.5"	"26.1"	"71.8"	"117.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P1K2"	"Polyamine-modulated factor 1 OS=Homo sapiens OX=9606 GN=PMF1 PE=1 SV=2"	"6"	"1"	"2"	"1"	"205"	"23.3"	"5.49"	"355.66"	"4.11"	"1"	"1"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf03980"	"100527963; 11243"	"ENSG00000160783"	"PMF1"	"A8K0C5; hsa:100527963; hsa:11243; Q5TCJ8; Q5TCJ9; Q5TCK0; Q5TCK1; Q5TCK3; Q69YZ9; Q6P1K2; Q6PHR4; Q6ZVE6; Q86VJ6; Q8N4T6; Q9UBQ3"	""	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"6"	"0"	"13.8"	"15.2"	"20.5"	"18.9"	"19.8"	"18.0"	"17.9"	"41.1"	"165.4"	"504.5"	"768.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H9Q4"	"Non-homologous end-joining factor 1 OS=Homo sapiens OX=9606 GN=NHEJ1 PE=1 SV=1"	"5"	"1"	"2"	"1"	"299"	"33.3"	"5.97"	"588.33"	"4.11"	"1"	"1"	"DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09302"	"79840"	"ENSG00000187736"	"NHEJ1"	"B8ZZA4; hsa:79840; Q4ZFW7; Q6IA64; Q96JS9; Q9H9Q4"	"Non-homologous end joining; DNA repair pathways, full network"	"Nonhomologous End-Joining (NHEJ)"	"3"	"0"	"59.3"	"42.8"	"57.2"	"55.1"	"53.6"	"58.6"	"84.0"	"121.2"	"401.7"	"489.9"	"497.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6PI98"	"INO80 complex subunit C OS=Homo sapiens OX=9606 GN=INO80C PE=1 SV=1"	"7"	"1"	"2"	"1"	"192"	"20.6"	"10.02"	"514.23"	"4.11"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus"	""	"Pf08265"	"125476"	"ENSG00000153391"	"INO80C"	"B4DUI4; E9PCS7; hsa:125476; Q6PI98; Q86WR1; Q8N994"	""	"UCH proteinases; DNA Damage Recognition in GG-NER"	"2"	"0"	"10.1"	"9.0"	"14.5"	"12.8"	"6.6"	"11.4"	"14.9"	"12.5"	"53.8"	"119.3"	"149.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P37198"	"Nuclear pore glycoprotein p62 OS=Homo sapiens OX=9606 GN=NUP62 PE=1 SV=3"	"3"	"1"	"2"	"1"	"522"	"53.2"	"5.31"	"426.67"	"4.11"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"other membranes;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf05064"	"23636"	"ENSG00000213024"	"NUP62"	"B3KWU5; hsa:23636; P37198; Q503A4; Q6GTM2; Q96C43; Q9NSL1"	"7q11.23 copy number variation syndrome"	"Nuclear Pore Complex (NPC) Disassembly; HCMV Early Events; Transport of Mature mRNA derived from an Intron-Containing Transcript; HCMV Late Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Postmitotic nuclear pore complex (NPC) reformation"	"30"	"0"	"25.6"	"30.0"	"29.8"	"18.4"	"28.1"	"34.3"	"40.0"	"45.7"	"103.9"	"240.1"	"388.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15008"	"26S proteasome non-ATPase regulatory subunit 6 OS=Homo sapiens OX=9606 GN=PSMD6 PE=1 SV=1"	"3"	"1"	"1"	"1"	"389"	"45.5"	"5.62"	""	"4.11"	""	"1"	"protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	""	"Pf01399, Pf10602"	"9861"	"ENSG00000163636"	"PSMD6"	"A8K2E0; E9PHI9; hsa:9861; Q15008; Q6UV22"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"AUF1 (hnRNP D0) binds and destabilizes mRNA; Regulation of expression of SLITs and ROBOs; ABC-family proteins mediated transport; Neutrophil degranulation; Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Interleukin-1 signaling; Separation of Sister Chromatids; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"64"	"0"	"74.3"	"64.2"	"82.5"	"66.9"	"79.0"	"72.7"	"85.4"	"137.8"	"291.5"	"834.9"	"1944.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NP81"	"Serine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=SARS2 PE=1 SV=1"	"4"	"2"	"3"	"2"	"518"	"58.2"	"8.13"	"626.47"	"4.10"	"2"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00587"	"54938"	"ENSG00000104835; ENSG00000283104"	"SARS2"	"A6NHW7; B4DE10; hsa:54938; Q9BVP3; Q9NP81"	""	"Mitochondrial tRNA aminoacylation"	"1"	"0"	"15.7"	"13.3"	"20.1"	"17.1"	"21.1"	"25.6"	"32.1"	"37.2"	"85.5"	"266.8"	"509.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5C9Z4"	"Nucleolar MIF4G domain-containing protein 1 OS=Homo sapiens OX=9606 GN=NOM1 PE=1 SV=1"	"5"	"1"	"1"	"1"	"860"	"96.2"	"8.10"	""	"4.09"	""	"1"	"other biological processes"	"nucleus"	""	"Pf02847, Pf02854"	"64434"	"ENSG00000146909"	"NOM1"	"hsa:64434; Q5C9Z4; Q96I08"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q14166"	"Tubulin--tyrosine ligase-like protein 12 OS=Homo sapiens OX=9606 GN=TTLL12 PE=1 SV=2"	"2"	"1"	"2"	"1"	"644"	"74.4"	"5.53"	"395.57"	"4.09"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03133"	"23170"	"ENSG00000100304"	"TTLL12"	"hsa:23170; Q14166; Q20WK5; Q9UGU3"	""	"Carboxyterminal post-translational modifications of tubulin"	"1"	"0"	"46.9"	"48.6"	"49.8"	"52.3"	"52.4"	"60.4"	"71.4"	"91.3"	"139.6"	"184.9"	"292.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96RN5"	"Mediator of RNA polymerase II transcription subunit 15 OS=Homo sapiens OX=9606 GN=MED15 PE=1 SV=2"	"2"	"1"	"2"	"1"	"788"	"86.7"	"9.42"	"509.39"	"4.07"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf09606"	"51586"	"ENSG00000099917"	"MED15"	"D3DX31; D3DX32; hsa:51586; O15413; Q6IC31; Q8NF16; Q96CT0; Q96IH7; Q96RN5; Q9P1T3"	"Sterol regulatory element-binding proteins (SREBP) signaling; SREBF and miR33 in cholesterol and lipid homeostasis; 22q11.2 copy number variation syndrome"	"PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; Generic Transcription Pathway"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q69YN4"	"Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2"	"1"	"1"	"2"	"1"	"1812"	"201.9"	"5.01"	"518.95"	"4.06"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf15912"	"25962"	"ENSG00000164944"	"VIRMA"	"hsa:25962; Q2M1N0; Q69YN4; Q6AHX9; Q6NT78; Q7Z6C7; Q8IXH4; Q9BTH4; Q9H9C9; Q9NWR3; Q9P2B8; Q9UFW1"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15212"	"Prefoldin subunit 6 OS=Homo sapiens OX=9606 GN=PFDN6 PE=1 SV=1"	"16"	"2"	"3"	"2"	"129"	"14.6"	"8.88"	"734.38"	"4.06"	"2"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"other cell component"	"other molecular function"	"Pf01920"	"10471"	"ENSG00000204220; ENSG00000206283; ENSG00000224782; ENSG00000235692; ENSG00000237335"	"PFDN6"	"hsa:10471; O15212"	"Cellular proteostasis"	"Prefoldin mediated transfer of substrate  to CCT/TriC"	"2"	"0"	"5.0"	"4.6"	"3.9"	"6.6"	"7.4"	"4.1"	"3.8"	"8.3"	"32.6"	"141.8"	"265.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H081"	"Protein MIS12 homolog OS=Homo sapiens OX=9606 GN=MIS12 PE=1 SV=1"	"5"	"1"	"2"	"1"	"205"	"24.1"	"5.69"	"384.32"	"4.05"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf05859"	"79003"	"ENSG00000167842"	"MIS12"	"hsa:79003; Q96N24; Q9H081"	""	"Resolution of Sister Chromatid Cohesion; Separation of Sister Chromatids; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"6"	"0"	"58.5"	"46.5"	"49.0"	"27.9"	"42.1"	"50.9"	"60.3"	"89.9"	"337.2"	"507.8"	"576.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60341"	"Lysine-specific histone demethylase 1A OS=Homo sapiens OX=9606 GN=KDM1A PE=1 SV=2"	"2"	"1"	"2"	"1"	"852"	"92.8"	"6.52"	"352.86"	"4.05"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01593, Pf04433"	"23028"	"ENSG00000004487"	"KDM1A"	"A8MWP9; hsa:23028; O60341; Q5TH94; Q5TH95; Q86VT7; Q8IXK4; Q8NDP6; Q8TAZ3; Q96AW4"	"Androgen receptor signaling pathway; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; Thermogenesis; Vitamin D-sensitive calcium signaling in depression; Thyroid hormones production and peripheral downstream signaling effects; Neurogenesis regulation in the olfactory epithelium"	"Estrogen-dependent gene expression; Potential therapeutics for SARS; Regulation of PTEN gene transcription; HDACs deacetylate histones; Factors involved in megakaryocyte development and platelet production; HDMs demethylate histones; NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3"	"14"	"0"	"36.0"	"36.7"	"44.4"	"27.4"	"44.7"	"31.5"	"41.5"	"54.9"	"114.8"	"358.0"	"856.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96FK6"	"WD repeat-containing protein 89 OS=Homo sapiens OX=9606 GN=WDR89 PE=2 SV=1"	"3"	"1"	"2"	"1"	"387"	"43.2"	"6.13"	"514.07"	"4.05"	"1"	"1"	"developmental processes"	""	""	"Pf00400"	"112840"	"ENSG00000140006"	"WDR89"	"hsa:112840; Q96FK6"	""	""	"0"	"0"	"18.1"	"16.8"	"21.0"	"15.6"	"19.4"	"16.0"	"27.9"	"32.5"	"85.2"	"344.6"	"455.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BTV4"	"Transmembrane protein 43 OS=Homo sapiens OX=9606 GN=TMEM43 PE=1 SV=1"	"4"	"1"	"2"	"1"	"400"	"44.8"	"8.13"	"431.24"	"4.05"	"1"	"1"	"cell organization and biogenesis;stress response"	"plasma membrane;other membranes;ER/Golgi;nucleus"	"other molecular function"	"Pf07787"	"79188"	"ENSG00000170876"	"TMEM43"	"hsa:79188; Q7L4N5; Q8NC30; Q96A63; Q96F19; Q96JX0; Q9BTV4; Q9H076"	"Envelope proteins and their potential roles in EDMD physiopathology"	""	"1"	"0"	"12.9"	"16.2"	"19.6"	"9.2"	"17.3"	"15.4"	"19.1"	"34.3"	"70.8"	"155.1"	"258.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95619"	"YEATS domain-containing protein 4 OS=Homo sapiens OX=9606 GN=YEATS4 PE=1 SV=1"	"11"	"2"	"3"	"2"	"227"	"26.5"	"8.41"	"978.81"	"4.02"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"other membranes;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03366"	"8089"	"ENSG00000127337"	"YEATS4"	"hsa:8089; O95619; Q9NQD0"	""	"HATs acetylate histones; Activation of the TFAP2 (AP-2) family of transcription factors"	"2"	"0"	"224.4"	"201.0"	"203.7"	"194.9"	"212.8"	"247.8"	"267.5"	"375.0"	"584.8"	"1136.0"	"1635.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q969X6"	"U3 small nucleolar RNA-associated protein 4 homolog OS=Homo sapiens OX=9606 GN=UTP4 PE=1 SV=1"	"3"	"1"	"1"	"1"	"686"	"76.8"	"8.85"	""	"4.00"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf00400"	"84916"	"ENSG00000141076; ENSG00000262788"	"UTP4"	"hsa:84916; Q8NCD9; Q8TF14; Q969X6; Q96SP0; Q96SR9; Q96SZ9; Q96T13; Q9BWK6"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"20.7"	"26.2"	"27.5"	"29.4"	"27.3"	"29.7"	"38.7"	"40.9"	"85.4"	"127.2"	"152.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6IA86"	"Elongator complex protein 2 OS=Homo sapiens OX=9606 GN=ELP2 PE=1 SV=2"	"1"	"1"	"1"	"1"	"826"	"92.4"	"5.96"	""	"4.00"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00400"	"55250"	"ENSG00000134759"	"ELP2"	"A8KAI6; B4DTG0; B4DXP0; E7EP23; E9PCX0; hsa:55250; Q53GZ0; Q687Y8; Q6IA86; Q8N5C2; Q96GV4; Q96PI7; Q9H9N0; Q9NV81"	""	"HATs acetylate histones"	"1"	"0"	"7.3"	"5.3"	"6.1"	"5.2"	"7.8"	"7.8"	"7.8"	"12.7"	"37.5"	"161.1"	"419.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NRW3"	"DNA dC->dU-editing enzyme APOBEC-3C OS=Homo sapiens OX=9606 GN=APOBEC3C PE=1 SV=2"	"8"	"1"	"1"	"1"	"190"	"22.8"	"7.59"	""	"3.99"	""	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf18782"	"27350"	"ENSG00000244509"	"APOBEC3C"	"B2R884; hsa:27350; Q5JZ92; Q7Z2N7; Q96F12; Q9NRW3"	""	"Formation of the Editosome"	"2"	"0"	"12.8"	"7.4"	"10.3"	"12.9"	"12.4"	"8.9"	"10.5"	"15.5"	"37.0"	"67.0"	"103.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NYB9"	"Abl interactor 2 OS=Homo sapiens OX=9606 GN=ABI2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"513"	"55.6"	"6.16"	"270.91"	"3.99"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf07815, Pf14604"	"10152"	"ENSG00000138443"	"ABI2"	"B4DSN1; hsa:10152; Q13147; Q13249; Q13801; Q9BV70; Q9NYB9"	"Regulation of actin cytoskeleton"	"RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; VEGFA-VEGFR2 Pathway"	"8"	"0"	"84.6"	"83.3"	"92.9"	"84.3"	"104.8"	"83.1"	"113.5"	"130.3"	"206.0"	"414.7"	"682.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P78537"	"Biogenesis of lysosome-related organelles complex 1 subunit 1 OS=Homo sapiens OX=9606 GN=BLOC1S1 PE=1 SV=2"	"7"	"1"	"2"	"1"	"153"	"17.3"	"9.33"	"374.36"	"3.98"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	""	"Pf06320"	"2647"	"ENSG00000135441"	"BLOC1S1"	"A1L4Q9; hsa:2647; P78537; Q6NZ45"	"Alstrom syndrome"	"Lysosome Vesicle Biogenesis; Golgi Associated Vesicle Biogenesis"	"3"	"0"	"5.0"	"7.1"	"8.5"	"7.0"	"8.5"	"8.5"	"10.1"	"13.2"	"45.0"	"167.2"	"252.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86TU7"	"Actin-histidine N-methyltransferase OS=Homo sapiens OX=9606 GN=SETD3 PE=1 SV=1"	"2"	"1"	"2"	"1"	"594"	"67.2"	"5.96"	"417.29"	"3.97"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00856, Pf09273"	"84193"	"ENSG00000183576"	"SETD3"	"A0PJU3; A5PLP0; B4DZE8; hsa:84193; Q0VAQ2; Q659C0; Q86TU7; Q86TU8; Q96GY9; Q9H5U5"	"Histone modifications"	"PKMTs methylate histone lysines"	"2"	"0"	"25.6"	"25.9"	"38.5"	"23.5"	"33.6"	"28.4"	"40.6"	"63.3"	"198.5"	"385.9"	"417.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UG63"	"ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2"	"4"	"2"	"3"	"2"	"623"	"71.2"	"7.37"	"722.47"	"3.97"	"2"	"1"	""	""	"other molecular function"	"Pf00005, Pf12848"	"10061; 114483834"	"ENSG00000033050"	"ABCF2"	"hsa:10061; hsa:114483834; O60864; Q75MJ0; Q75MJ1; Q96TE8; Q9UG63"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"8.6"	"8.4"	"7.3"	"8.4"	"8.3"	"9.0"	"7.4"	"13.8"	"19.6"	"22.0"	"24.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92896"	"Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1179"	"134.5"	"6.90"	"342.17"	"3.97"	"1"	"1"	"protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"extracellular matrix;plasma membrane;other membranes;cytoskeleton;ER/Golgi"	"signal transduction activity or receptor binding;other molecular function"	"Pf00839"	"2734"	"ENSG00000090863"	"GLG1"	"B7Z8Y4; D3DUJ7; hsa:2734; Q13221; Q6P9D1; Q92896"	""	"Cell surface interactions at the vascular wall"	"1"	"0"	"79.4"	"54.2"	"68.2"	"58.9"	"85.0"	"55.3"	"68.7"	"89.0"	"172.9"	"268.7"	"351.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N122"	"Regulatory-associated protein of mTOR OS=Homo sapiens OX=9606 GN=RPTOR PE=1 SV=1"	"1"	"1"	"2"	"1"	"1335"	"148.9"	"6.89"	"437.80"	"3.97"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00400, Pf02985, Pf14538"	"57521"	"ENSG00000141564"	"RPTOR"	"B2RN36; C6KEF2; F5H7J5; hsa:57521; Q8N122; Q8N4V9; Q8TB32; Q9P2P3"	"AMP-activated protein kinase signaling; Target of rapamycin signaling; PI3K-AKT-mTOR signaling pathway and therapeutic opportunities in prostate cancer; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Clear cell renal cell carcinoma pathways; PI3K-Akt signaling pathway; Thermogenesis; Synaptic signaling pathways associated with autism spectrum disorder; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Head and neck squamous cell carcinoma; Thyroid hormones production and peripheral downstream signaling effects; IL-18 signaling pathway; CAMKK2 pathway; Autophagy; p53 transcriptional gene network; Pleural mesothelioma; Network map of SARS-CoV-2 signaling pathway; GDNF signaling; DYRK1A involvement regarding cell proliferation in brain development; JAK-STAT signaling in the regulation of Beta-cells; Interferon type I signaling pathways"	"Regulation of PTEN gene transcription; TP53 Regulates Metabolic Genes; Amino acids regulate mTORC1; mTORC1-mediated signalling; Macroautophagy; Energy dependent regulation of mTOR by LKB1-AMPK; HSF1-dependent transactivation"	"33"	"0"	"23.3"	"13.0"	"16.0"	"15.8"	"17.4"	"12.1"	"15.9"	"27.5"	"47.9"	"110.8"	"170.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13084"	"39S ribosomal protein L28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL28 PE=1 SV=4"	"7"	"2"	"3"	"2"	"256"	"30.1"	"8.29"	"748.20"	"3.95"	"2"	"1"	"protein metabolism;other metabolic processes"	"other membranes;cytosol;mitochondrion;translational apparatus"	"other molecular function"	"Pf00830"	"10573"	"ENSG00000086504"	"MRPL28"	"B2RCM4; D3DU46; hsa:10573; Q13084; Q4TT39; Q96S26; Q9BQD8; Q9BR04"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"263.8"	"261.7"	"236.9"	"197.5"	"219.5"	"267.9"	"277.1"	"374.7"	"475.4"	"874.4"	"1702.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y223"	"Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase OS=Homo sapiens OX=9606 GN=GNE PE=1 SV=1"	"2"	"1"	"2"	"1"	"722"	"79.2"	"6.80"	"458.26"	"3.93"	"1"	"1"	"cell adhesion;other metabolic processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00480, Pf02350"	"10020"	"ENSG00000159921"	"GNE"	"A6PZH2; A6PZH3; A7UNU7; B2R6E1; B7Z372; B7Z428; D3DRP7; F5H499; H0YFA7; hsa:10020; Q0VA94; Q9Y223"	""	"Sialic acid metabolism; Defective GNE causes sialuria, NK and IBM2"	"2"	"0"	"11.7"	"9.2"	"14.6"	"12.7"	"15.6"	"12.8"	"17.7"	"15.5"	"37.4"	"114.4"	"191.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P27144"	"Adenylate kinase 4, mitochondrial OS=Homo sapiens OX=9606 GN=AK4 PE=1 SV=1"	"5"	"1"	"2"	"1"	"223"	"25.3"	"8.40"	"395.87"	"3.93"	"1"	"1"	"other metabolic processes;stress response;other biological processes"	"mitochondrion;other cell component"	"kinase activity;other molecular function"	"Pf00406, Pf05191"	"205"	"ENSG00000162433"	"AK4"	"B2R927; D3DQ62; hsa:205; P27144; Q6IBH4; Q6NXQ5; Q8IUU9"	"CCL18 signaling pathway"	"Interconversion of nucleotide di- and triphosphates"	"2"	"0"	"4.2"	"5.6"	"4.5"	"5.4"	"7.9"	"12.9"	"11.4"	"4.3"	"29.6"	"175.5"	"426.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKG9"	"Peroxisomal carnitine O-octanoyltransferase OS=Homo sapiens OX=9606 GN=CROT PE=1 SV=2"	"3"	"1"	"2"	"1"	"612"	"70.1"	"7.08"	"447.25"	"3.92"	"1"	"1"	"other metabolic processes;transport"	"cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00755"	"54677"	"ENSG00000005469"	"CROT"	"A4D1D6; E7EQF2; hsa:54677; Q86V17; Q8IUW9; Q9UKG9; Q9Y6I2"	""	"Peroxisomal protein import; Beta-oxidation of pristanoyl-CoA"	"2"	"0"	"0.0"	"0.0"	"4.5"	"4.1"	"2.4"	"5.7"	"3.7"	"7.5"	"24.2"	"47.8"	"71.4"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2K7"	"Lysine-specific demethylase 2A OS=Homo sapiens OX=9606 GN=KDM2A PE=1 SV=3"	"1"	"1"	"2"	"1"	"1162"	"132.7"	"7.58"	"548.20"	"3.92"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00646, Pf02008, Pf16866, Pf17811"	"22992"	"ENSG00000173120"	"KDM2A"	"D4QA03; E9PIL6; hsa:22992; I3VM55; Q49A21; Q4G0M3; Q69YY8; Q9BVH5; Q9H7H5; Q9UK66; Q9Y2K7"	""	"HDMs demethylate histones"	"1"	"0"	"14.9"	"15.1"	"13.8"	"18.2"	"18.4"	"16.7"	"16.8"	"24.4"	"34.2"	"58.7"	"70.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H939"	"Proline-serine-threonine phosphatase-interacting protein 2 OS=Homo sapiens OX=9606 GN=PSTPIP2 PE=1 SV=4"	"4"	"1"	"2"	"1"	"334"	"38.8"	"8.48"	"295.71"	"3.92"	"1"	"1"	"cell organization and biogenesis"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf00611"	"9050"	"ENSG00000152229"	"PSTPIP2"	"hsa:9050; Q9H939"	""	""	"0"	"0"	"43.7"	"23.5"	"48.5"	"52.3"	"49.9"	"41.2"	"54.3"	"62.2"	"91.7"	"92.8"	"129.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H7E2"	"Tudor domain-containing protein 3 OS=Homo sapiens OX=9606 GN=TDRD3 PE=1 SV=1"	"2"	"1"	"2"	"1"	"651"	"73.1"	"9.23"	"396.60"	"3.92"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00567, Pf00627, Pf08585"	"81550"	"ENSG00000083544"	"TDRD3"	"B2MWP9; hsa:81550; Q53XA6; Q6P992; Q9H7E2"	""	""	"0"	"0"	"7.9"	"9.5"	"9.8"	"7.8"	"6.0"	"10.1"	"13.2"	"15.7"	"19.7"	"27.6"	"36.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y535"	"DNA-directed RNA polymerase III subunit RPC8 OS=Homo sapiens OX=9606 GN=POLR3H PE=1 SV=1"	"7"	"1"	"2"	"1"	"204"	"22.9"	"4.58"	"432.91"	"3.91"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;stress response"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03876, Pf08292"	"171568"	"ENSG00000100413"	"POLR3H"	"B0QYH9; hsa:171568; Q5M7Y8; Q96AE3; Q9BY95; Q9Y535"	"Pyrimidine metabolism; Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway; Primary ovarian insufficiency"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation"	"11"	"0"	"6.5"	"11.8"	"10.7"	"10.4"	"9.6"	"7.7"	"13.0"	"16.2"	"27.8"	"53.9"	"97.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N8S7"	"Protein enabled homolog OS=Homo sapiens OX=9606 GN=ENAH PE=1 SV=2"	"5"	"2"	"4"	"2"	"591"	"66.5"	"6.93"	"1216.22"	"3.91"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00568, Pf08776"	"55740"	"ENSG00000154380"	"ENAH"	"D0PQI2; hsa:55740; Q502W5; Q5T5M7; Q5VTQ9; Q5VTR0; Q8N8S7; Q9NVF3; Q9UFB8"	"Regulation of actin cytoskeleton"	"Generation of second messenger molecules; Signaling by ROBO receptors"	"3"	"0"	"175.6"	"161.3"	"165.6"	"160.0"	"198.1"	"187.4"	"209.7"	"229.9"	"282.8"	"454.5"	"675.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q68CP9"	"AT-rich interactive domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ARID2 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1835"	"197.3"	"7.42"	"349.39"	"3.91"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01388, Pf02257"	"196528"	"ENSG00000189079"	"ARID2"	"hsa:196528; Q15KG9; Q5EB51; Q645I3; Q68CP9; Q6ZRY5; Q7Z3I5; Q86T28; Q96SJ6; Q9HCL5"	""	"RMTs methylate histone arginines; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"	"2"	"0"	"22.1"	"15.9"	"19.5"	"10.9"	"14.5"	"15.5"	"24.7"	"23.7"	"37.0"	"65.6"	"96.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9C0B0"	"RING finger protein unkempt homolog OS=Homo sapiens OX=9606 GN=UNK PE=1 SV=2"	"1"	"1"	"2"	"1"	"810"	"88.0"	"6.86"	"381.30"	"3.91"	"1"	"1"	"developmental processes;other biological processes"	"other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00642, Pf18384"	"85451"	"ENSG00000132478"	"UNK"	"hsa:85451; Q9C0B0"	""	""	"0"	"0"	"23.2"	"25.4"	"22.5"	"17.2"	"23.0"	"26.9"	"28.5"	"33.0"	"53.7"	"70.4"	"119.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UL63"	"Muskelin OS=Homo sapiens OX=9606 GN=MKLN1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"735"	"84.7"	"6.34"	"410.44"	"3.91"	"1"	"1"	"cell adhesion;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01344, Pf06588, Pf13415"	"4289"	"ENSG00000128585"	"MKLN1"	"A4D1M8; A6NG43; hsa:4289; Q9NSK4; Q9NUS8; Q9UL63"	"Ciliary landscape"	""	"1"	"0"	"3.4"	"8.1"	"7.3"	"6.9"	"11.5"	"6.6"	"6.6"	"11.3"	"18.2"	"43.4"	"91.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6Y288"	"Beta-1,3-glucosyltransferase OS=Homo sapiens OX=9606 GN=B3GLCT PE=1 SV=2"	"3"	"1"	"2"	"1"	"498"	"56.5"	"7.50"	"309.27"	"3.90"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf02434"	"145173"	"ENSG00000187676"	"B3GLCT"	"A8K5F8; hsa:145173; Q5W0H2; Q6NUI3; Q6Y288"	""	"Defective B3GALTL causes PpS; O-glycosylation of TSR domain-containing proteins"	"2"	"0"	"20.5"	"17.7"	"21.4"	"22.3"	"24.0"	"37.0"	"37.0"	"61.6"	"181.7"	"454.8"	"710.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61962"	"DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1"	"4"	"1"	"2"	"1"	"342"	"38.9"	"5.52"	"338.32"	"3.88"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00400"	"10238"	"ENSG00000136485"	"DCAF7"	"B4E039; D3DU14; hsa:10238; O15491; P61962; Q9DAE4"	"Ciliary landscape; DYRK1A involvement regarding cell proliferation in brain development"	"Neddylation; Association of TriC/CCT with target proteins during biosynthesis"	"4"	"0"	"37.9"	"48.6"	"43.0"	"36.4"	"37.3"	"44.4"	"57.8"	"85.8"	"121.9"	"183.3"	"258.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13685"	"Angio-associated migratory cell protein OS=Homo sapiens OX=9606 GN=AAMP PE=1 SV=2"	"3"	"1"	"1"	"1"	"434"	"46.7"	"4.42"	""	"3.87"	""	"1"	"developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00400"	"14"	"ENSG00000127837"	"AAMP"	"hsa:14; Q13685; Q8WUJ9; Q96H92"	"Nucleotide-binding oligomerization domain (NOD) pathway"	"NOD1/2 Signaling Pathway; Thromboxane signalling through TP receptor; Signaling by EGFR; Signaling by VEGF"	"5"	"0"	"12.3"	"12.3"	"14.4"	"12.6"	"12.3"	"10.3"	"15.1"	"14.7"	"25.7"	"51.6"	"118.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P86790"	"Vacuolar fusion protein CCZ1 homolog B OS=Homo sapiens OX=9606 GN=CCZ1B PE=1 SV=1"	"4"	"1"	"1"	"1"	"482"	"55.8"	"6.48"	""	"3.87"	""	"1"	"transport"	"other membranes;other cytoplasmic organelle;other cell component"	""	"Pf19031, Pf19032, Pf19033"	"221960; 51622"	"ENSG00000146574"	"CCZ1B"	"A2RU45; hsa:221960; hsa:51622; O95766; P86790; Q9UG65; Q9Y359"	""	"RAB GEFs exchange GTP for GDP on RABs"	"1"	"0"	"16.2"	"19.6"	"14.6"	"19.6"	"20.3"	"16.7"	"21.3"	"23.7"	"53.3"	"87.9"	"134.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NP50"	"SIN3-HDAC complex-associated factor OS=Homo sapiens OX=9606 GN=SINHCAF PE=1 SV=1"	"10"	"1"	"1"	"1"	"221"	"24.8"	"9.41"	""	"3.87"	""	"1"	"other biological processes"	"nucleus"	""	"Pf15396"	"58516"	"ENSG00000139146; ENSG00000276371"	"SINHCAF"	"D3DUV8; hsa:58516; Q9BSZ8; Q9NP50"	""	""	"0"	"0"	"7.2"	"7.8"	"10.0"	"7.0"	"9.1"	"6.4"	"9.9"	"9.1"	"22.0"	"32.2"	"53.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UIJ7"	"GTP:AMP phosphotransferase AK3, mitochondrial OS=Homo sapiens OX=9606 GN=AK3 PE=1 SV=4"	"5"	"1"	"1"	"1"	"227"	"25.6"	"9.16"	""	"3.86"	""	"1"	"other metabolic processes;stress response"	"mitochondrion;other cell component"	"kinase activity;other molecular function"	"Pf00406, Pf05191"	"50808"	"ENSG00000147853"	"AK3"	"B4DP58; D3DRI1; E7ET30; hsa:50808; Q5VYW6; Q9H576; Q9HC01; Q9NPB4; Q9UIJ7"	""	"Factors involved in megakaryocyte development and platelet production"	"1"	"0"	"7.4"	"5.7"	"5.9"	"5.5"	"7.9"	"7.4"	"9.7"	"22.2"	"25.2"	"61.4"	"102.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92738"	"USP6 N-terminal-like protein OS=Homo sapiens OX=9606 GN=USP6NL PE=1 SV=3"	"2"	"1"	"2"	"1"	"828"	"94.0"	"9.07"	"438.41"	"3.86"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00566"	"9712"	"ENSG00000148429"	"USP6NL"	"A8KA79; hsa:9712; Q15400; Q5VV10; Q7L0K9; Q92738"	"EGF/EGFR signaling pathway"	"Retrograde transport at the Trans-Golgi-Network"	"2"	"0"	"33.3"	"29.0"	"28.6"	"25.1"	"29.2"	"25.6"	"44.9"	"49.5"	"44.6"	"74.0"	"93.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P38117"	"Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3"	"5"	"1"	"2"	"1"	"255"	"27.8"	"8.10"	"445.08"	"3.86"	"1"	"1"	"other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf01012"	"2109"	"ENSG00000105379"	"ETFB"	"A8K766; B3KNY2; hsa:2109; P38117; Q6IBH7; Q71RF6; Q9Y3S7"	""	"Respiratory electron transport; Protein methylation"	"2"	"0"	"17.6"	"23.4"	"21.4"	"18.3"	"19.7"	"21.3"	"21.6"	"41.8"	"58.0"	"103.5"	"194.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96C19"	"EF-hand domain-containing protein D2 OS=Homo sapiens OX=9606 GN=EFHD2 PE=1 SV=1"	"5"	"1"	"2"	"1"	"240"	"26.7"	"5.20"	"394.92"	"3.86"	"1"	"1"	""	"other membranes"	"other molecular function"	"Pf13499"	"79180"	"ENSG00000142634"	"EFHD2"	"hsa:79180; Q5JYW9; Q96C19"	""	"RHOD GTPase cycle"	"1"	"0"	"21.2"	"22.9"	"28.1"	"22.0"	"23.6"	"24.9"	"31.2"	"41.4"	"88.0"	"139.1"	"251.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43314"	"Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 OS=Homo sapiens OX=9606 GN=PPIP5K2 PE=1 SV=3"	"2"	"2"	"3"	"2"	"1243"	"140.3"	"8.22"	"721.43"	"3.86"	"2"	"1"	"other metabolic processes;other biological processes"	"cytosol"	"kinase activity;other molecular function"	"Pf00328, Pf18086"	"23262"	"ENSG00000145725"	"PPIP5K2"	"A1NI53; A6NGS8; hsa:23262; O43314; Q8TB50"	""	"Synthesis of pyrophosphates in the cytosol"	"1"	"0"	"41.7"	"37.4"	"42.8"	"42.0"	"43.6"	"44.0"	"55.6"	"72.4"	"190.6"	"316.1"	"349.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q3SYG4"	"Protein PTHB1 OS=Homo sapiens OX=9606 GN=BBS9 PE=1 SV=1"	"2"	"1"	"2"	"1"	"887"	"99.2"	"5.55"	"449.20"	"3.84"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	""	"Pf14727, Pf14728"	"27241"	"ENSG00000122507"	"BBS9"	"E9PDC9; hsa:27241; P78514; Q3SYG4; Q7KYS6; Q7KYS7; Q8N570; Q99844; Q99854; Q9Y699; Q9Y6A0"	"Ciliary landscape; Genes related to primary cilium development (based on CRISPR); Joubert syndrome; Ciliopathies; Bardet-Biedl syndrome"	"BBSome-mediated cargo-targeting to cilium"	"6"	"0"	"12.9"	"11.8"	"22.7"	"13.9"	"19.3"	"18.1"	"22.1"	"29.4"	"72.6"	"132.0"	"145.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51648"	"Aldehyde dehydrogenase family 3 member A2 OS=Homo sapiens OX=9606 GN=ALDH3A2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"485"	"54.8"	"7.88"	"357.57"	"3.84"	"1"	"1"	"other metabolic processes;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00171"	"224"	"ENSG00000072210"	"ALDH3A2"	"hsa:224; P51648; Q6I9T3; Q93011; Q96J37"	"Fragile X syndrome; Fluoroacetic acid toxicity"	"RND2 GTPase cycle; RND1 GTPase cycle"	"4"	"0"	"10.9"	"10.0"	"12.5"	"12.2"	"16.9"	"10.6"	"11.9"	"21.1"	"40.7"	"126.6"	"204.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60903"	"Protein S100-A10 OS=Homo sapiens OX=9606 GN=S100A10 PE=1 SV=2"	"18"	"1"	"2"	"1"	"97"	"11.2"	"7.37"	"657.64"	"3.84"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf01023"	"6281"	"ENSG00000197747"	"S100A10"	"A8K4V8; hsa:6281; P08206; P60903; Q5T1C5"	"8p23.1 copy number variation syndrome; Prostaglandin synthesis and regulation"	"Dissolution of Fibrin Clot"	"3"	"0"	"57.6"	"51.6"	"57.8"	"50.4"	"52.7"	"51.8"	"65.9"	"74.9"	"139.9"	"184.6"	"262.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07992"	"DNA excision repair protein ERCC-1 OS=Homo sapiens OX=9606 GN=ERCC1 PE=1 SV=1"	"4"	"1"	"2"	"1"	"297"	"32.5"	"6.25"	"372.62"	"3.83"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00633, Pf03834"	"2067"	"ENSG00000012061"	"ERCC1"	"B2RC01; B3KRR0; hsa:2067; P07992; Q7Z7F5; Q96S40"	"Male infertility; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"Fanconi Anemia Pathway; Dual incision in TC-NER; HDR through Single Strand Annealing (SSA); Formation of Incision Complex in GG-NER; Dual Incision in GG-NER"	"9"	"0"	"32.5"	"33.1"	"37.1"	"37.9"	"36.3"	"37.9"	"38.8"	"52.5"	"173.3"	"358.5"	"549.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92616"	"eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6"	"0"	"1"	"2"	"1"	"2671"	"292.6"	"7.47"	"432.71"	"3.82"	"1"	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"25.9"	"28.4"	"27.6"	"22.5"	"22.6"	"29.2"	"32.8"	"58.2"	"172.2"	"243.7"	"292.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96L91"	"E1A-binding protein p400 OS=Homo sapiens OX=9606 GN=EP400 PE=1 SV=4"	"0"	"1"	"2"	"1"	"3159"	"343.3"	"9.19"	"424.32"	"3.82"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf07529, Pf15790"	"57634"	"ENSG00000183495"	"EP400"	"hsa:57634; O15411; Q6P2F5; Q8N8Q7; Q8NE05; Q96JK7; Q96L91; Q9P230"	""	"Formation of Senescence-Associated Heterochromatin Foci (SAHF); HATs acetylate histones"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P12830"	"Cadherin-1 OS=Homo sapiens OX=9606 GN=CDH1 PE=1 SV=3"	"2"	"1"	"2"	"1"	"882"	"97.4"	"4.73"	"362.18"	"3.82"	"1"	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00028, Pf01049, Pf08758"	"999"	"ENSG00000039068"	"CDH1"	"A8K1U7; hsa:999; P12830; Q13799; Q14216; Q15855; Q16194; Q4PJ14; Q9UII8"	"Neural crest differentiation; Pathogenic Escherichia coli infection; Mammary gland development pathway - Embryonic development (Stage 1 of 4); Mammary gland development pathway - Involution (Stage 4 of 4); Bladder cancer; Pre-implantation embryo; H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity; Endometrial cancer; Epithelial to mesenchymal transition in colorectal cancer; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; Gastrin signaling pathway; Melanoma; Pleural mesothelioma; CCL18 signaling pathway; TROP2 regulatory signaling; CKAP4 signaling pathway map; 10q11.21q11.23 copy number variation syndrome; A network map of Macrophage-stimulating protein (MSP) signaling"	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell; Degradation of the extracellular matrix; RHO GTPases activate IQGAPs; Integrin cell surface interactions; Formation of definitive endoderm; Adherens junctions interactions; InlA-mediated entry of Listeria monocytogenes into host cells; Apoptotic cleavage of cell adhesion  proteins"	"28"	"0"	"21.6"	"20.2"	"19.0"	"19.6"	"23.9"	"26.0"	"30.7"	"31.6"	"48.7"	"100.6"	"152.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50914"	"60S ribosomal protein L14 OS=Homo sapiens OX=9606 GN=RPL14 PE=1 SV=4"	"6"	"1"	"2"	"1"	"215"	"23.4"	"10.93"	"325.43"	"3.82"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01929"	"9045"	"ENSG00000188846"	"RPL14"	"hsa:9045; P50914; Q45RF0; Q53G20; Q8TBD5; Q8WUT0; Q92579; Q96GR0; Q9BSB8; Q9BW65; Q9BYF6"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"15.8"	"16.6"	"17.9"	"10.2"	"81.1"	"20.5"	"30.3"	"29.3"	"65.0"	"135.0"	"173.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2X3"	"Nucleolar protein 58 OS=Homo sapiens OX=9606 GN=NOP58 PE=1 SV=1"	"4"	"2"	"3"	"2"	"529"	"59.5"	"8.92"	"606.30"	"3.82"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01798, Pf08156"	"51602"	"ENSG00000055044"	"NOP58"	"hsa:51602; Q53SA4; Q6PK08; Q9P036; Q9UFN3; Q9Y2X3"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; SUMOylation of RNA binding proteins; rRNA modification in the nucleus and cytosol"	"3"	"0"	"134.7"	"126.5"	"159.8"	"129.2"	"153.6"	"168.1"	"186.5"	"209.5"	"426.8"	"725.8"	"1056.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQ15"	"SOSS complex subunit B1 OS=Homo sapiens OX=9606 GN=NABP2 PE=1 SV=1"	"10"	"2"	"3"	"2"	"211"	"22.3"	"9.06"	"749.62"	"3.80"	"2"	"1"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01336"	"79035"	"ENSG00000139579"	"NABP2"	"A6NDF8; hsa:79035; Q6XYC8; Q9BQ15"	"Mesodermal commitment pathway"	"RNA polymerase II transcribes snRNA genes"	"2"	"0"	"119.5"	"108.4"	"141.3"	"125.4"	"137.2"	"138.3"	"174.1"	"195.5"	"313.7"	"608.1"	"859.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9ULM3"	"YEATS domain-containing protein 2 OS=Homo sapiens OX=9606 GN=YEATS2 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1422"	"150.7"	"8.98"	"329.59"	"3.80"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf03366"	"55689"	"ENSG00000163872"	"YEATS2"	"A7E2B9; D3DNS9; hsa:55689; Q641P6; Q9NW96; Q9ULM3"	""	"HATs acetylate histones; Formation of WDR5-containing histone-modifying complexes"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H446"	"RWD domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RWDD1 PE=1 SV=1"	"5"	"1"	"2"	"1"	"243"	"27.9"	"4.20"	"479.80"	"3.78"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"other cell component"	""	"Pf05773"	"51389"	"ENSG00000111832"	"RWDD1"	"A8K3W2; A8MT24; hsa:51389; Q9H446; Q9Y313; Q9Y6B3"	""	""	"0"	"0"	"48.3"	"44.9"	"57.2"	"50.2"	"56.3"	"59.2"	"59.4"	"68.4"	"113.6"	"261.9"	"422.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UPY8"	"Microtubule-associated protein RP/EB family member 3 OS=Homo sapiens OX=9606 GN=MAPRE3 PE=1 SV=1"	"4"	"1"	"2"	"1"	"281"	"32.0"	"5.54"	"350.10"	"3.78"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf03271"	"22924"	"ENSG00000084764"	"MAPRE3"	"B7WPK5; hsa:22924; O00265; Q6FHB0; Q6FI15; Q9BZP7; Q9BZP8; Q9UPY8"	""	""	"0"	"0"	"16.8"	"16.7"	"22.4"	"26.9"	"28.0"	"27.5"	"26.3"	"43.7"	"96.1"	"163.7"	"236.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3A3"	"MOB-like protein phocein OS=Homo sapiens OX=9606 GN=MOB4 PE=1 SV=1"	"10"	"2"	"3"	"2"	"225"	"26.0"	"5.78"	"699.97"	"3.77"	"2"	"1"	""	"other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf03637"	"25843"	"ENSG00000115540"	"MOB4"	"B4DML0; hsa:25843; Q53SE0; Q7Z4Y6; Q9H2P3; Q9H5J1; Q9Y3A3; Q9Y4T8"	""	""	"0"	"0"	"66.1"	"68.7"	"71.7"	"56.0"	"72.1"	"71.5"	"84.3"	"103.7"	"165.5"	"370.9"	"528.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43639"	"Cytoplasmic protein NCK2 OS=Homo sapiens OX=9606 GN=NCK2 PE=1 SV=2"	"6"	"1"	"1"	"1"	"380"	"42.9"	"6.95"	""	"3.76"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00017, Pf00018, Pf14604"	"8440"	"ENSG00000071051"	"NCK2"	"D3DVK1; hsa:8440; O43639; Q9BWN9; Q9UIC3"	"Pathogenic Escherichia coli infection; Brain-derived neurotrophic factor (BDNF) signaling pathway; EGF/EGFR signaling pathway; Genes controlling nephrogenesis; ErbB signaling pathway"	"RHOV GTPase cycle; RHOU GTPase cycle; Nephrin family interactions; Downstream signal transduction; VEGFA-VEGFR2 Pathway; Ephrin signaling; Activation of RAC1; Regulation of cortical dendrite branching"	"13"	"0"	"5.7"	"5.9"	"3.2"	"4.2"	"3.8"	"6.0"	"5.0"	"9.9"	"19.0"	"58.3"	"115.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKZ1"	"CCR4-NOT transcription complex subunit 11 OS=Homo sapiens OX=9606 GN=CNOT11 PE=1 SV=1"	"3"	"1"	"2"	"1"	"510"	"55.2"	"6.40"	"476.60"	"3.76"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf10155"	"55571"	"ENSG00000158435"	"CNOT11"	"hsa:55571; Q6P2M9; Q8N681; Q9UKZ1"	""	"Deadenylation of mRNA; TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BT09"	"Protein canopy homolog 3 OS=Homo sapiens OX=9606 GN=CNPY3 PE=1 SV=1"	"4"	"1"	"2"	"1"	"278"	"30.7"	"5.49"	"356.87"	"3.76"	"1"	"1"	"stress response"	"ER/Golgi"	"signal transduction activity or receptor binding"	"Pf11938"	"10695"	"ENSG00000137161"	"CNPY3"	"hsa:10695; O15412; Q0P6I2; Q8NF54; Q8WTU8; Q9BT09; Q9P0F2"	""	"Trafficking and processing of endosomal TLR"	"1"	"0"	"4.1"	"2.6"	"5.7"	"5.5"	"2.3"	"3.3"	"4.3"	"6.8"	"116.2"	"204.4"	"238.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5QJE6"	"Deoxynucleotidyltransferase terminal-interacting protein 2 OS=Homo sapiens OX=9606 GN=DNTTIP2 PE=1 SV=2"	"3"	"2"	"3"	"2"	"756"	"84.4"	"6.16"	"544.84"	"3.75"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf08698"	"30836"	"ENSG00000067334"	"DNTTIP2"	"hsa:30836; Q12987; Q53H59; Q5QJE6; Q5TFJ4; Q6TLI0; Q76MJ8; Q86WX9"	""	""	"0"	"0"	"138.4"	"138.7"	"126.0"	"126.2"	"117.8"	"144.2"	"144.7"	"180.2"	"301.9"	"643.6"	"945.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4B6"	"DDB1- and CUL4-associated factor 1 OS=Homo sapiens OX=9606 GN=DCAF1 PE=1 SV=3"	"1"	"1"	"2"	"1"	"1507"	"168.9"	"5.06"	"315.71"	"3.75"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	""	"9730"	"ENSG00000145041"	"DCAF1"	"hsa:9730; Q2YD74; Q8TBD9; Q9HCA1; Q9UG37; Q9Y4B6"	"Hippo-Merlin signaling dysregulation"	"Antigen processing: Ubiquitination & Proteasome degradation"	"2"	"0"	"25.2"	"25.7"	"28.1"	"20.0"	"27.1"	"26.1"	"27.5"	"42.8"	"65.1"	"112.2"	"144.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKD1"	"Glucocorticoid modulatory element-binding protein 2 OS=Homo sapiens OX=9606 GN=GMEB2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"530"	"56.4"	"5.60"	"331.81"	"3.74"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01342"	"26205"	"ENSG00000101216"	"GMEB2"	"E1P5J3; hsa:26205; Q5TDS0; Q9H431; Q9H4X7; Q9H4X8; Q9UF78; Q9UKD1; Q9ULF1"	""	""	"0"	"0"	"9.2"	"11.6"	"4.7"	"5.0"	"10.7"	"7.1"	"12.7"	"17.7"	"45.5"	"137.3"	"226.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14692"	"Ribosome biogenesis protein BMS1 homolog OS=Homo sapiens OX=9606 GN=BMS1 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1282"	"145.7"	"6.44"	"386.63"	"3.74"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04950, Pf08142"	"9790"	"ENSG00000165733"	"BMS1"	"hsa:9790; Q14692; Q5QPT5; Q86XJ9"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HD47"	"Ran guanine nucleotide release factor OS=Homo sapiens OX=9606 GN=RANGRF PE=1 SV=1"	"7"	"1"	"2"	"1"	"186"	"20.4"	"4.94"	"404.41"	"3.74"	"1"	"1"	"transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf04603"	"29098"	"ENSG00000108961"	"RANGRF"	"D3DTR6; hsa:29098; Q68DI3; Q9BR68; Q9HD47; Q9HD48; Q9NRU9; Q9P001; Q9P0P2"	""	"Phase 0 - rapid depolarisation"	"1"	"0"	"10.3"	"9.8"	"14.1"	"12.4"	"11.1"	"8.7"	"9.3"	"12.3"	"15.5"	"30.1"	"26.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6ZN04"	"RNA-binding protein MEX3B OS=Homo sapiens OX=9606 GN=MEX3B PE=1 SV=1"	"3"	"1"	"2"	"1"	"569"	"58.8"	"6.90"	"481.58"	"3.73"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf13920"	"84206"	"ENSG00000183496"	"MEX3B"	"hsa:84206; Q4G0W1; Q6ZN04; Q8IVG2; Q9H0J0"	""	""	"0"	"0"	"10.4"	"20.5"	"9.3"	"4.4"	"7.9"	"12.5"	"10.7"	"17.9"	"18.7"	"39.6"	"34.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P40763"	"Signal transducer and activator of transcription 3 OS=Homo sapiens OX=9606 GN=STAT3 PE=1 SV=2"	"2"	"1"	"2"	"1"	"770"	"88.0"	"6.30"	"488.84"	"3.73"	"1"	"1"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00017, Pf01017, Pf02864, Pf02865"	"6774"	"ENSG00000168610"	"STAT3"	"A8K7B8; hsa:6774; K7ENL3; O14916; P40763; Q9BW54"	"IL-5 signaling pathway; Androgen receptor signaling pathway; Physiological and pathological hypertrophy of the heart; MicroRNAs in cardiomyocyte hypertrophy; Transcription factors regulate miRNAs related to cardiac hypertrophy; Cell differentiation - expanded index; Cell differentiation - index; Thyroid stimulating hormone (TSH) signaling pathway; Leptin signaling pathway; Prolactin signaling pathway; Microtubule cytoskeleton regulation; IL-7 signaling pathway; IL-17 signaling pathway; IL-9 signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; Androgen receptor network in prostate cancer; AGE/RAGE pathway; Interleukin-11 signaling pathway; Adipogenesis; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Mammary gland development pathway - Involution (Stage 4 of 4); Dopaminergic neurogenesis; IL-3 signaling pathway; TCA cycle nutrient use and invasiveness of ovarian cancer; Estrogen receptor pathway; Nuclear receptors meta-pathway; Kit receptor signaling pathway; Hepatocyte growth factor receptor signaling; RAC1/PAK1/p38/MMP2 pathway; IL6 signaling pathway; Hepatitis C and hepatocellular carcinoma; VEGFA-VEGFR2 signaling; Development of pulmonary dendritic cells and macrophage subsets; Chemokine signaling pathway; Embryonic stem cell pluripotency pathways; Leptin-insulin signaling overlap; IL-4 signaling pathway; Prion disease pathway; Clear cell renal cell carcinoma pathways; Non-small cell lung cancer; Pancreatic adenocarcinoma pathway; Acute viral myocarditis; Extracellular vesicles in the crosstalk of cardiac cells; ncRNAs involved in STAT3 signaling in hepatocellular carcinoma; EGF/EGFR signaling pathway; IL-10 anti-inflammatory signaling pathway ; Regulatory circuits of the STAT3 signaling pathway; Interactions between immune cells and microRNAs in tumor microenvironment; Neural crest cell migration during development; Neural crest cell migration in cancer; Cancer immunotherapy by PD-1 blockade; Measles virus infection; Gastrin signaling pathway; Hepatitis B infection; EGFR tyrosine kinase inhibitor resistance; TGF-beta receptor signaling in skeletal dysplasias; mBDNF and proBDNF regulation of GABA neurotransmission; IL-2 signaling pathway; Neuroinflammation and glutamatergic signaling; CCL18 signaling pathway; Th17 cell differentiation pathway; Urotensin-II-mediated signaling pathway; Inflammatory bowel disease signaling; 2q11.2 copy number variation syndrome; 2q21.1 copy number variation syndrome; Neurogenesis regulation in the olfactory epithelium; Autophagy in pancreatic ductal adenocarcinoma; IL-26 signaling pathways; JAK-STAT signaling in the regulation of Beta-cells; TAR syndrome; Role of hypoxia, angiogenesis, and FGF pathway in OA chondrocyte hypertrophy; TGF-beta receptor signaling; EPO receptor signaling; Interferon type I signaling pathways; Notch signaling pathway; Serotonin HTR1 group and FOS pathway"	"Interleukin-4 and Interleukin-13 signaling; Senescence-Associated Secretory Phenotype (SASP); Interleukin-7 signaling; Signaling by SCF-KIT; Downstream signal transduction; Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants; Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants; Signaling by PDGFRA extracellular domain mutants; Cytoprotection by HMOX1; Association of TriC/CCT with target proteins during biosynthesis; Interleukin-10 signaling; Growth hormone receptor signaling; Interleukin-6 signaling; Signaling by Leptin; PTK6 Activates STAT3; Inactivation of CSF3 (G-CSF) signaling; Signaling by cytosolic FGFR1 fusion mutants; Signaling by CSF1 (M-CSF) in myeloid cells; STAT3 nuclear events downstream of ALK signaling; BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members; POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation; Interleukin-20 family signaling; Interleukin-35 Signalling; Interleukin-23 signaling; Interleukin-27 signaling; Transcriptional regulation of granulopoiesis; Interleukin-37 signaling; Signalling to STAT3; Nuclear events stimulated by ALK signaling in cancer; MET activates STAT3; Interleukin-15 signaling; Interleukin-9 signaling; Interleukin-21 signaling"	"114"	"0"	"36.4"	"41.2"	"38.8"	"32.4"	"44.6"	"39.7"	"52.0"	"59.0"	"116.7"	"316.7"	"525.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31277"	"Homeobox protein Hox-D11 OS=Homo sapiens OX=9606 GN=HOXD11 PE=3 SV=3"	"6"	"1"	"1"	"1"	"338"	"35.2"	"8.84"	""	"3.71"	""	"1"	"developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00046, Pf12045"	"3237"	"ENSG00000128713"	"HOXD11"	"A6NIS4; hsa:3237; P31277; Q9NS02"	"Genes controlling nephrogenesis; Development of ureteric collection system"	""	"2"	"0"	"13.6"	"14.6"	"16.1"	"14.0"	"19.1"	"18.0"	"14.7"	"21.9"	"28.5"	"48.5"	"46.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WVX9"	"Fatty acyl-CoA reductase 1 OS=Homo sapiens OX=9606 GN=FAR1 PE=1 SV=1"	"3"	"1"	"2"	"1"	"515"	"59.3"	"9.17"	"408.13"	"3.71"	"1"	"1"	"other metabolic processes"	"other membranes;other cytoplasmic organelle"	"other molecular function"	"Pf03015, Pf07993"	"84188"	"ENSG00000197601"	"FAR1"	"D3DQW8; hsa:84188; Q5CZA3; Q8WVX9"	""	"Wax biosynthesis"	"1"	"0"	"13.7"	"20.6"	"7.8"	"13.1"	"12.8"	"10.3"	"23.3"	"18.3"	"44.8"	"102.3"	"176.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60573"	"Eukaryotic translation initiation factor 4E type 2 OS=Homo sapiens OX=9606 GN=EIF4E2 PE=1 SV=1"	"7"	"1"	"1"	"1"	"245"	"28.3"	"8.88"	""	"3.71"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01652"	"9470"	"ENSG00000135930"	"EIF4E2"	"B8ZZJ9; hsa:9470; O60573; O75349"	"Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; EGFR tyrosine kinase inhibitor resistance"	"ISG15 antiviral mechanism"	"4"	"0"	"54.4"	"33.6"	"62.5"	"45.9"	"50.3"	"56.9"	"58.9"	"49.8"	"87.7"	"112.6"	"156.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P17677"	"Neuromodulin OS=Homo sapiens OX=9606 GN=GAP43 PE=1 SV=1"	"8"	"1"	"2"	"1"	"238"	"24.8"	"4.72"	"313.85"	"3.70"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00612, Pf06614, Pf10580"	"2596"	"ENSG00000172020"	"GAP43"	"A8K0Y4; hsa:2596; P17677"	"Glial cell differentiation; Spinal cord injury"	"L1CAM interactions"	"3"	"0"	"0.0"	"2.6"	"2.4"	"2.5"	"0.0"	"0.0"	"7.4"	"4.8"	"6.9"	"41.2"	"101.8"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q4U2R6"	"39S ribosomal protein L51, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL51 PE=1 SV=1"	"9"	"1"	"3"	"1"	"128"	"15.1"	"11.27"	"859.15"	"3.70"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf10244"	"51258"	"ENSG00000111639"	"MRPL51"	"hsa:51258; Q4U2R6; Q96Q57; Q9BQ36; Q9P0N7"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"76.9"	"78.1"	"115.2"	"81.7"	"85.7"	"91.7"	"111.5"	"158.5"	"213.8"	"410.1"	"818.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5VZ89"	"DENN domain-containing protein 4C OS=Homo sapiens OX=9606 GN=DENND4C PE=1 SV=3"	"1"	"1"	"2"	"1"	"1909"	"212.6"	"6.83"	"374.52"	"3.69"	"1"	"1"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity"	"Pf02141, Pf03455, Pf03456"	"55667"	"ENSG00000137145"	"DENND4C"	"A2A3R1; A2A3R2; A2A3R3; A2A3R9; hsa:55667; Q5VZ89; Q6AI48; Q6ZUB3; Q8NCY7; Q9H6N4; Q9NUT1; Q9NWA5; Q9NWT3; R4GN35; R4GNB2"	""	"RAB GEFs exchange GTP for GDP on RABs"	"1"	"0"	"20.5"	"13.1"	"28.0"	"23.6"	"29.8"	"18.0"	"26.1"	"35.5"	"58.9"	"126.6"	"154.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H1B7"	"Probable E3 ubiquitin-protein ligase IRF2BPL OS=Homo sapiens OX=9606 GN=IRF2BPL PE=1 SV=1"	"2"	"1"	"2"	"1"	"796"	"82.6"	"8.24"	"299.07"	"3.69"	"1"	"1"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus"	"other molecular function"	"Pf11261"	"64207"	"ENSG00000119669"	"IRF2BPL"	"hsa:64207; Q8NDQ2; Q96JG2; Q9H1B7; Q9H3I7"	""	""	"0"	"0"	"30.9"	"27.6"	"39.0"	"38.4"	"42.5"	"35.7"	"43.5"	"46.0"	"103.2"	"165.0"	"229.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63173"	"60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2"	"23"	"2"	"3"	"1"	"70"	"8.2"	"10.10"	"672.56"	"3.69"	"2"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01781"	"6169"	"ENSG00000172809"	"RPL38"	"B2R5A8; hsa:6169; P23411; P63173"	"Mesodermal commitment pathway; Mesodermal commitment pathway; Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; SRP-dependent cotranslational protein targeting to membrane; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"16"	"0"	"80.8"	"59.5"	"85.3"	"76.5"	"91.9"	"96.7"	"101.5"	"98.3"	"176.9"	"265.5"	"315.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96P48"	"Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ARAP1 PE=1 SV=3"	"1"	"1"	"2"	"1"	"1450"	"162.1"	"6.23"	"344.07"	"3.68"	"1"	"1"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf00536, Pf00620, Pf00788, Pf01412"	"116985"	"ENSG00000186635"	"ARAP1"	"A3KLL7; B2RTS2; hsa:116985; O94879; Q4LDD5; Q59FI7; Q6PHS3; Q8WU51; Q96HP6; Q96L71; Q96P48"	""	"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q2M2I8"	"AP2-associated protein kinase 1 OS=Homo sapiens OX=9606 GN=AAK1 PE=1 SV=3"	"1"	"1"	"2"	"1"	"961"	"103.8"	"6.60"	"308.12"	"3.68"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"signal transduction activity or receptor binding;kinase activity;other molecular function"	"Pf00069"	"22848"	"ENSG00000115977"	"AAK1"	"hsa:22848; Q2M2I8; Q4ZFZ3; Q53RX6; Q9UPV4"	""	"Cargo recognition for clathrin-mediated endocytosis"	"2"	"0"	"11.3"	"11.5"	"10.5"	"12.0"	"10.2"	"11.8"	"12.9"	"13.3"	"24.8"	"46.2"	"62.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00273"	"DNA fragmentation factor subunit alpha OS=Homo sapiens OX=9606 GN=DFFA PE=1 SV=1"	"6"	"2"	"2"	"2"	"331"	"36.5"	"4.79"	"235.79"	"3.68"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02017, Pf09033"	"1676"	"ENSG00000160049"	"DFFA"	"hsa:1676; O00273; Q5T6G5; Q5T6G6; Q96I97; Q9Y6C6"	"Apoptosis; Fas ligand pathway and stress induction of heat shock proteins; Acute viral myocarditis"	"Apoptosis induced DNA fragmentation"	"4"	"0"	"109.1"	"79.3"	"138.1"	"122.0"	"110.9"	"82.8"	"139.4"	"181.5"	"208.6"	"323.3"	"727.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62891"	"60S ribosomal protein L39 OS=Homo sapiens OX=9606 GN=RPL39 PE=1 SV=2"	"20"	"1"	"2"	"1"	"51"	"6.4"	"12.56"	"369.03"	"3.68"	"1"	"1"	"protein metabolism;other metabolic processes;stress response"	"non-structural extracellular;cytosol;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00832"	"6170"	"ENSG00000198918"	"RPL39"	"hsa:6170; P02404; P39025; P62891; Q9BYF2"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"64.1"	"38.5"	"69.1"	"61.2"	"64.7"	"66.6"	"73.4"	"92.9"	"104.6"	"133.0"	"188.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96JM7"	"Lethal(3)malignant brain tumor-like protein 3 OS=Homo sapiens OX=9606 GN=L3MBTL3 PE=1 SV=2"	"2"	"1"	"2"	"1"	"780"	"88.3"	"6.46"	"398.32"	"3.67"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"nucleus"	"other molecular function"	"Pf00536, Pf02820"	"84456"	"ENSG00000198945"	"L3MBTL3"	"hsa:84456; Q4VXE1; Q5VUM9; Q6P9B5; Q96JM7"	""	""	"0"	"0"	"11.5"	"29.2"	"7.7"	"12.0"	"18.8"	"12.5"	"18.9"	"30.7"	"45.4"	"64.7"	"76.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94804"	"Serine/threonine-protein kinase 10 OS=Homo sapiens OX=9606 GN=STK10 PE=1 SV=1"	"1"	"1"	"2"	"1"	"968"	"112.1"	"6.95"	"358.04"	"3.67"	"1"	"1"	"cell adhesion;cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf12474"	"6793"	"ENSG00000072786"	"STK10"	"A6ND35; B2R8F5; B3KMY1; hsa:6793; O94804; Q6NSK0; Q9UIW4"	""	"RHOC GTPase cycle; RHOA GTPase cycle; RHOB GTPase cycle; Neutrophil degranulation"	"4"	"0"	"44.7"	"41.5"	"36.8"	"46.1"	"45.0"	"51.8"	"85.4"	"115.8"	"91.5"	"76.1"	"75.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96FZ2"	"Abasic site processing protein HMCES OS=Homo sapiens OX=9606 GN=HMCES PE=1 SV=1"	"3"	"1"	"2"	"1"	"354"	"40.5"	"8.15"	"299.12"	"3.66"	"1"	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02586"	"56941"	"ENSG00000183624"	"HMCES"	"A6NJR9; hsa:56941; Q96FZ2; Q96G34; Q9NRP3"	""	""	"0"	"0"	"19.2"	"21.9"	"18.2"	"15.2"	"21.4"	"17.1"	"23.7"	"37.4"	"74.9"	"152.9"	"205.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P12532"	"Creatine kinase U-type, mitochondrial OS=Homo sapiens OX=9606 GN=CKMT1A PE=1 SV=1"	"2"	"1"	"2"	"1"	"417"	"47.0"	"8.34"	"457.44"	"3.66"	"1"	"1"	"other metabolic processes"	"other membranes;mitochondrion"	"kinase activity;other molecular function"	"Pf00217, Pf02807"	"1159; 548596"	"ENSG00000223572; ENSG00000237289"	"CKMT1A; CKMT1B"	"B4DIT8; B7ZA09; hsa:1159; hsa:548596; P12532; Q0VAM3; Q32NF6; Q53FC4"	""	"Creatine metabolism"	"1"	"0"	"88.6"	"82.0"	"93.7"	"80.0"	"81.2"	"89.3"	"105.7"	"125.0"	"246.8"	"392.9"	"607.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WVK2"	"U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP27 PE=1 SV=1"	"17"	"2"	"3"	"2"	"155"	"18.8"	"11.62"	"807.58"	"3.65"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf08648"	"11017"	"ENSG00000124380"	"SNRNP27"	"hsa:11017; Q15410; Q8WVK2"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"54.7"	"49.6"	"62.5"	"57.9"	"56.0"	"58.8"	"62.3"	"73.4"	"208.3"	"506.6"	"643.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92575"	"UBX domain-containing protein 4 OS=Homo sapiens OX=9606 GN=UBXN4 PE=1 SV=2"	"3"	"1"	"2"	"1"	"508"	"56.7"	"6.38"	"336.71"	"3.65"	"1"	"1"	"protein metabolism;other metabolic processes;stress response"	"other membranes;cytosol;ER/Golgi;nucleus"	""	"Pf00789"	"23190"	"ENSG00000144224"	"UBXN4"	"A8K9W4; hsa:23190; Q4ZG56; Q8IYM5; Q92575"	""	""	"0"	"0"	"17.1"	"19.5"	"12.8"	"13.2"	"18.8"	"17.7"	"19.5"	"27.3"	"45.7"	"125.7"	"172.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75947"	"ATP synthase subunit d, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PD PE=1 SV=3"	"13"	"1"	"1"	"1"	"161"	"18.5"	"5.30"	""	"3.64"	""	"1"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf05873"	"10476"	"ENSG00000167863"	"ATP5PD"	"B2R5L6; hsa:10476; O75947; Q9H3J4"	"Electron transport chain: OXPHOS system in mitochondria; Oxidative phosphorylation"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NX63"	"MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1"	"5"	"1"	"2"	"1"	"227"	"26.1"	"8.28"	"385.84"	"3.64"	"1"	"1"	"cell organization and biogenesis"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf05300"	"54927"	"ENSG00000106554"	"CHCHD3"	"hsa:54927; Q9NX63"	""	"Cristae formation; Mitochondrial protein import"	"2"	"0"	"38.4"	"38.2"	"47.4"	"37.1"	"49.7"	"52.1"	"51.7"	"46.1"	"108.9"	"238.1"	"367.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P20936"	"Ras GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RASA1 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1047"	"116.3"	"6.54"	"323.63"	"3.63"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00017, Pf00018, Pf00168, Pf00169, Pf00616"	"5921"	"ENSG00000145715"	"RASA1"	"B2R6W3; B4DTL2; hsa:5921; P20936; Q68CU6; Q9UDI1"	"Androgen receptor network in prostate cancer; PDGF pathway; T cell receptor and co-stimulatory signaling; Hepatocyte growth factor receptor signaling; RAC1/PAK1/p38/MMP2 pathway; MAPK signaling pathway; Ras signaling; Acute viral myocarditis; EGF/EGFR signaling pathway; GDNF signaling; EPO receptor signaling"	"Regulation of RAS by GAPs; EPHB-mediated forward signaling; Downstream signal transduction; VEGFR2 mediated cell proliferation; PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"	"16"	"0"	"0.0"	"5.6"	"2.9"	"4.4"	"5.6"	"4.7"	"8.0"	"8.4"	"120.0"	"313.4"	"479.9"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H583"	"HEAT repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=HEATR1 PE=1 SV=3"	"1"	"1"	"2"	"1"	"2144"	"242.2"	"6.54"	"470.74"	"3.63"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity"	"Pf08146, Pf12397"	"55127"	"ENSG00000119285"	"HEATR1"	"hsa:55127; Q5T3Q8; Q6P197; Q9H583; Q9NW23"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"9.6"	"10.7"	"11.7"	"10.7"	"12.3"	"9.2"	"17.7"	"20.0"	"54.0"	"80.8"	"91.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P16219"	"Short-chain specific acyl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ACADS PE=1 SV=1"	"3"	"1"	"2"	"1"	"412"	"44.3"	"7.99"	"353.27"	"3.62"	"1"	"1"	"other metabolic processes"	"cytoskeleton;mitochondrion;nucleus"	"other molecular function"	"Pf00441, Pf02770, Pf02771"	"35"	"ENSG00000122971"	"ACADS"	"hsa:35; P16219; P78331"	"Fatty acid beta-oxidation; Mitochondrial long chain fatty acid beta-oxidation; IL-18 signaling pathway; Mitochondrial fatty acid oxidation disorders"	"Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of butanoyl-CoA to acetyl-CoA"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H6F5"	"Coiled-coil domain-containing protein 86 OS=Homo sapiens OX=9606 GN=CCDC86 PE=1 SV=1"	"5"	"1"	"2"	"1"	"360"	"40.2"	"10.33"	"509.27"	"3.62"	"1"	"1"	""	"nucleus;other cell component"	""	"Pf03879"	"79080"	"ENSG00000110104"	"CCDC86"	"B4DY99; hsa:79080; Q9H6F5"	""	""	"0"	"0"	"10.6"	"7.6"	"6.8"	"8.2"	"10.7"	"8.7"	"9.7"	"11.7"	"12.1"	"23.2"	"42.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96DE0"	"U8 snoRNA-decapping enzyme OS=Homo sapiens OX=9606 GN=NUDT16 PE=1 SV=2"	"8"	"1"	"2"	"1"	"195"	"21.3"	"6.89"	"467.35"	"3.61"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00293"	"131870"	"ENSG00000198585"	"NUDT16"	"B4E3B4; E9PED4; F5GYJ1; hsa:131870; Q96DE0; Q96N82"	""	"Phosphate bond hydrolysis by NUDT proteins"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49005"	"DNA polymerase delta subunit 2 OS=Homo sapiens OX=9606 GN=POLD2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"469"	"51.3"	"5.58"	"360.05"	"3.60"	"1"	"1"	"DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf04042, Pf18018"	"5425"	"ENSG00000106628"	"POLD2"	"A4D2J4; B2R5S4; hsa:5425; P49005"	"Homologous recombination; Pyrimidine metabolism; DNA replication; Base excision repair; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Removal of the Flap Intermediate; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta); Polymerase switching on the C-strand of the telomere; Polymerase switching"	"25"	"0"	"39.6"	"36.6"	"55.1"	"41.5"	"46.6"	"51.7"	"47.5"	"73.5"	"134.4"	"209.4"	"277.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NXW2"	"DnaJ homolog subfamily B member 12 OS=Homo sapiens OX=9606 GN=DNAJB12 PE=1 SV=5"	"5"	"1"	"2"	"1"	"375"	"41.8"	"8.69"	"318.07"	"3.59"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response"	"other membranes;ER/Golgi;nucleus"	"other molecular function"	"Pf00226, Pf09320"	"54788"	"ENSG00000148719"	"DNAJB12"	"B7Z7I3; hsa:54788; Q9H6H0; Q9NXW2"	""	""	"0"	"0"	"11.2"	"11.2"	"15.3"	"12.3"	"19.8"	"12.7"	"20.0"	"17.9"	"30.7"	"54.3"	"62.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q93096"	"Protein tyrosine phosphatase type IVA 1 OS=Homo sapiens OX=9606 GN=PTP4A1 PE=1 SV=2"	"7"	"1"	"3"	"1"	"173"	"19.8"	"8.97"	"725.06"	"3.58"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00782"	"7803"	"ENSG00000112245"	"PTP4A1"	"B2R6C8; hsa:7803; O00648; Q49A54; Q93096"	""	""	"0"	"0"	"30.4"	"22.3"	"32.5"	"25.9"	"32.8"	"27.3"	"45.0"	"53.9"	"110.4"	"166.1"	"205.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NS91"	"E3 ubiquitin-protein ligase RAD18 OS=Homo sapiens OX=9606 GN=RAD18 PE=1 SV=2"	"3"	"2"	"4"	"2"	"495"	"56.2"	"7.58"	"924.09"	"3.58"	"2"	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02037, Pf13923"	"56852"	"ENSG00000070950"	"RAD18"	"hsa:56852; Q58F55; Q9NRT6; Q9NS91"	"SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome"	"Recognition of DNA damage by PCNA-containing replication complex; E3 ubiquitin ligases ubiquitinate target proteins"	"3"	"0"	"123.2"	"106.2"	"152.3"	"122.3"	"139.0"	"141.7"	"144.1"	"195.4"	"317.8"	"492.0"	"609.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H9J2"	"39S ribosomal protein L44, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL44 PE=1 SV=1"	"3"	"1"	"2"	"1"	"332"	"37.5"	"8.40"	"346.81"	"3.58"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"plasma membrane;other membranes;mitochondrion;translational apparatus;nucleus"	"nucleic acid binding activity;other molecular function"	""	"65080"	"ENSG00000135900"	"MRPL44"	"hsa:65080; Q53S16; Q6IA62; Q9H821; Q9H9J2"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"37.2"	"40.0"	"37.0"	"41.6"	"38.0"	"41.4"	"52.4"	"57.8"	"97.1"	"163.6"	"268.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NYR9"	"NF-kappa-B inhibitor-interacting Ras-like protein 2 OS=Homo sapiens OX=9606 GN=NKIRAS2 PE=1 SV=1"	"6"	"1"	"2"	"1"	"191"	"21.5"	"8.05"	"357.09"	"3.58"	"1"	"1"	"stress response;developmental processes;signal transduction;other biological processes"	"other cell component"	"other molecular function"	"Pf00071"	"28511"	"ENSG00000168256"	"NKIRAS2"	"A6NCZ5; B3KNN0; B4DNM3; hsa:28511; Q6PK52; Q96KC7; Q9NSX1; Q9NYR9"	""	"RIP-mediated NFkB activation via ZBP1; TAK1-dependent IKK and NF-kappa-B activation  ; TRAF6 mediated NF-kB activation"	"3"	"0"	"18.8"	"16.5"	"17.2"	"10.6"	"19.6"	"23.6"	"40.1"	"61.0"	"132.1"	"188.6"	"212.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q56P03"	"E2F-associated phosphoprotein OS=Homo sapiens OX=9606 GN=EAPP PE=1 SV=4"	"4"	"1"	"2"	"1"	"285"	"32.7"	"5.12"	"464.04"	"3.58"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	""	"Pf10238"	"55837"	"ENSG00000129518"	"EAPP"	"hsa:55837; Q56P03; Q9BVF4; Q9NWV5; Q9NZ86"	""	""	"0"	"0"	"4.2"	"3.4"	"5.9"	"4.3"	"5.1"	"4.3"	"4.6"	"6.9"	"10.9"	"26.8"	"54.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N300"	"Small vasohibin-binding protein OS=Homo sapiens OX=9606 GN=SVBP PE=1 SV=1"	"35"	"2"	"3"	"2"	"66"	"7.8"	"9.16"	"631.46"	"3.57"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;transport;developmental processes;other biological processes"	"non-structural extracellular;cytoskeleton;other cell component"	"enzyme regulator activity;cytoskeletal activity"	"Pf15674"	"374969"	"ENSG00000177868"	"SVBP"	"A8K5P1; D3DPW7; hsa:374969; Q8N300"	""	"Carboxyterminal post-translational modifications of tubulin"	"1"	"0"	"76.4"	"68.5"	"92.8"	"91.1"	"99.8"	"97.4"	"116.4"	"177.3"	"401.3"	"587.5"	"709.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NT62"	"Ubiquitin-like-conjugating enzyme ATG3 OS=Homo sapiens OX=9606 GN=ATG3 PE=1 SV=1"	"4"	"1"	"2"	"1"	"314"	"35.8"	"4.74"	"402.13"	"3.57"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf03987"	"64422"	"ENSG00000144848"	"ATG3"	"hsa:64422; Q6PKC5; Q9H6L9; Q9NT62"	"Nanoparticle triggered autophagic cell death; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Autophagy; Clock-controlled autophagy in bone metabolism"	"Macroautophagy"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96B36"	"Proline-rich AKT1 substrate 1 OS=Homo sapiens OX=9606 GN=AKT1S1 PE=1 SV=1"	"5"	"1"	"2"	"1"	"256"	"27.4"	"4.75"	"348.56"	"3.57"	"1"	"1"	"cell organization and biogenesis;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf15798"	"84335"	"ENSG00000204673"	"AKT1S1"	"A8MTQ1; B2RE93; hsa:84335; J3KPM3; Q96B36; Q96BI4; Q96IK7; Q96NG2; Q9BWR5"	"Target of rapamycin signaling; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; VEGFA-VEGFR2 signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Clear cell renal cell carcinoma pathways; Thermogenesis; Fragile X syndrome; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Thyroid hormones production and peripheral downstream signaling effects; Autophagy; Perturbations to host-cell autophagy, induced by SARS-CoV-2 proteins; p53 transcriptional gene network; Pleural mesothelioma; Network map of SARS-CoV-2 signaling pathway; DYRK1A involvement regarding cell proliferation in brain development; JAK-STAT signaling in the regulation of Beta-cells"	"Constitutive Signaling by AKT1 E17K in Cancer; mTORC1-mediated signalling; AKT phosphorylates targets in the cytosol; HSF1-dependent transactivation"	"21"	"0"	"45.9"	"44.4"	"49.9"	"51.8"	"48.8"	"53.0"	"65.3"	"56.7"	"75.1"	"87.4"	"104.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13797"	"Plastin-3 OS=Homo sapiens OX=9606 GN=PLS3 PE=1 SV=4"	"2"	"1"	"2"	"1"	"630"	"70.8"	"5.60"	"368.21"	"3.57"	"1"	"1"	"cell organization and biogenesis;developmental processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf13499"	"5358"	"ENSG00000102024"	"PLS3"	"A8K579; B1AQ09; B4DGB4; B7Z6M1; hsa:5358; P13797; Q86YI6"	""	""	"0"	"0"	"20.5"	"31.8"	"27.6"	"22.8"	"17.3"	"20.9"	"28.6"	"42.1"	"69.4"	"122.5"	"168.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P00492"	"Hypoxanthine-guanine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=HPRT1 PE=1 SV=2"	"11"	"2"	"3"	"2"	"218"	"24.6"	"6.68"	"586.21"	"3.57"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;developmental processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00156"	"3251"	"ENSG00000165704"	"HPRT1"	"A6NHF0; B2R8M9; hsa:3251; P00492"	"Mesodermal commitment pathway"	"Azathioprine ADME; Purine salvage; Defective HPRT1 disrupts guanine and hypoxanthine salvage"	"4"	"0"	"40.2"	"58.7"	"45.8"	"45.6"	"41.6"	"32.5"	"52.1"	"78.8"	"121.8"	"207.9"	"249.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WUR7"	"UPF0235 protein C15orf40 OS=Homo sapiens OX=9606 GN=C15orf40 PE=1 SV=2"	"14"	"2"	"3"	"2"	"153"	"16.3"	"9.83"	"699.61"	"3.56"	"2"	"1"	""	"other cell component"	""	"Pf02594"	"123207"	"ENSG00000169609"	"C15orf40"	"A6NIC9; B2R5E7; F5GX92; F8WD31; G5EA00; hsa:123207; Q8WUR7"	"15q25 copy number variation"	""	"1"	"0"	"92.8"	"75.4"	"112.1"	"105.9"	"110.2"	"97.5"	"126.3"	"162.0"	"353.9"	"392.6"	"444.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62854"	"40S ribosomal protein S26 OS=Homo sapiens OX=9606 GN=RPS26 PE=1 SV=3"	"21"	"1"	"1"	"1"	"115"	"13.0"	"11.00"	""	"3.56"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01283"	"6231"	"ENSG00000197728"	"RPS26"	"hsa:6231; P02383; P62854; P70394; Q06722; Q3MHD8; Q6IRY4"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Peptide chain elongation; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"13.8"	"16.7"	"24.8"	"12.7"	"15.7"	"16.3"	"18.4"	"24.2"	"60.7"	"114.9"	"172.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P20962"	"Parathymosin OS=Homo sapiens OX=9606 GN=PTMS PE=1 SV=2"	"11"	"1"	"2"	"1"	"102"	"11.5"	"4.16"	"469.16"	"3.55"	"1"	"1"	"DNA metabolism;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf03247"	"5763"	"ENSG00000159335"	"PTMS"	"hsa:5763; P20962"	"IL-18 signaling pathway"	""	"1"	"0"	"260.0"	"198.2"	"249.4"	"233.9"	"240.4"	"261.6"	"290.7"	"280.2"	"266.0"	"264.8"	"269.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BRJ7"	"Tudor-interacting repair regulator protein OS=Homo sapiens OX=9606 GN=NUDT16L1 PE=1 SV=1"	"5"	"1"	"2"	"1"	"211"	"23.3"	"8.91"	"427.24"	"3.54"	"1"	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity"	""	"84309"	"ENSG00000168101"	"NUDT16L1"	"hsa:84309; Q8NAI2; Q9BRJ7"	""	""	"0"	"0"	"10.6"	"7.7"	"5.6"	"7.7"	"5.5"	"8.5"	"8.1"	"12.7"	"22.9"	"50.0"	"92.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H1A4"	"Anaphase-promoting complex subunit 1 OS=Homo sapiens OX=9606 GN=ANAPC1 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1944"	"216.4"	"6.30"	"412.38"	"3.54"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf12859, Pf18122, Pf19521, Pf20518"	"64682"	"ENSG00000153107"	"ANAPC1"	"hsa:64682; Q2M3H8; Q9BSE6; Q9H1A4; Q9H8D0"	"Cell cycle; 2q13 copy number variation syndrome"	"Senescence-Associated Secretory Phenotype (SASP); Separation of Sister Chromatids; Antigen processing: Ubiquitination & Proteasome degradation; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; CDK-mediated phosphorylation and removal of Cdc6; Autodegradation of Cdh1 by Cdh1:APC/C; Assembly of the pre-replicative complex; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of Cyclin B; Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase; Regulation of APC/C activators between G1/S and early anaphase; Phosphorylation of the APC/C; APC-Cdc20 mediated degradation of Nek2A; Transcriptional Regulation by VENTX; Aberrant regulation of mitotic exit in cancer due to RB1 defects"	"20"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96GG9"	"DCN1-like protein 1 OS=Homo sapiens OX=9606 GN=DCUN1D1 PE=1 SV=1"	"4"	"1"	"1"	"1"	"259"	"30.1"	"5.34"	""	"3.54"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf03556, Pf14555"	"54165"	"ENSG00000043093"	"DCUN1D1"	"B2RB37; hsa:54165; Q7L3G9; Q8TEX7; Q96GG9; Q9H6M1; Q9HCT3"	""	"Neddylation"	"1"	"0"	"0.0"	"0.0"	"0.0"	"2.2"	"0.0"	"0.0"	"0.0"	"2.1"	"3.8"	"54.0"	"136.3"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q00536"	"Cyclin-dependent kinase 16 OS=Homo sapiens OX=9606 GN=CDK16 PE=1 SV=1"	"3"	"1"	"1"	"1"	"496"	"55.7"	"7.62"	""	"3.53"	""	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"5127"	"ENSG00000102225"	"CDK16"	"A8K280; B7Z7C8; hsa:5127; J3KN74; J3KQP7; Q00536"	""	""	"0"	"0"	"13.6"	"20.4"	"19.9"	"20.0"	"18.5"	"21.0"	"21.2"	"26.0"	"57.6"	"118.0"	"160.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75718"	"Cartilage-associated protein OS=Homo sapiens OX=9606 GN=CRTAP PE=1 SV=1"	"3"	"1"	"2"	"1"	"401"	"46.5"	"5.73"	"343.71"	"3.53"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;ER/Golgi;other cell component"	""	""	"10491"	"ENSG00000170275"	"CRTAP"	"B2RBL6; hsa:10491; O75718"	"Type I collagen synthesis in the context of osteogenesis imperfecta"	"Collagen biosynthesis and modifying enzymes"	"2"	"0"	"32.8"	"50.5"	"50.5"	"37.6"	"42.3"	"31.7"	"47.0"	"86.4"	"164.6"	"233.2"	"316.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16514"	"Transcription initiation factor TFIID subunit 12 OS=Homo sapiens OX=9606 GN=TAF12 PE=1 SV=1"	"7"	"1"	"2"	"1"	"161"	"17.9"	"7.99"	"269.40"	"3.51"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03847"	"6883"	"ENSG00000120656"	"TAF12"	"D3DPM5; hsa:6883; Q15775; Q16514; Q5T077"	"Eukaryotic transcription initiation"	"HATs acetylate histones; Regulation of TP53 Activity through Phosphorylation; RNA Polymerase II Pre-transcription Events; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation"	"11"	"0"	"40.6"	"36.6"	"42.1"	"37.7"	"44.9"	"46.5"	"44.7"	"48.1"	"78.3"	"164.1"	"233.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43847"	"Nardilysin OS=Homo sapiens OX=9606 GN=NRDC PE=1 SV=3"	"1"	"1"	"2"	"1"	"1151"	"131.6"	"4.98"	"377.97"	"3.51"	"1"	"1"	"protein metabolism;other biological processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00675, Pf05193, Pf16187"	"4898"	"ENSG00000078618"	"NRDC"	"A6NI41; hsa:4898; O15241; O15242; O43847; Q5VUL0; Q96HB2; Q9NU57"	""	""	"0"	"0"	"18.1"	"15.5"	"23.0"	"18.0"	"20.5"	"17.6"	"31.6"	"39.3"	"61.8"	"114.5"	"176.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BRT9"	"DNA replication complex GINS protein SLD5 OS=Homo sapiens OX=9606 GN=GINS4 PE=1 SV=1"	"5"	"1"	"2"	"1"	"223"	"26.0"	"4.98"	"285.93"	"3.51"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	""	"Pf05916, Pf16922"	"84296"	"ENSG00000147536"	"GINS4"	"B2R8H5; D3DSY0; hsa:84296; Q8N648; Q9BRT9"	""	"Unwinding of DNA"	"1"	"0"	"9.7"	"16.7"	"11.0"	"10.8"	"11.9"	"13.2"	"14.9"	"22.4"	"23.3"	"33.0"	"50.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82675"	"28S ribosomal protein S5, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS5 PE=1 SV=2"	"3"	"1"	"2"	"1"	"430"	"48.0"	"9.92"	"446.65"	"3.50"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00333, Pf03719"	"64969"	"ENSG00000144029"	"MRPS5"	"hsa:64969; P82675; Q4ZFY5; Q96LJ6; Q9BWI4; Q9BYC4"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"48.9"	"38.5"	"57.7"	"55.7"	"52.2"	"57.4"	"57.6"	"60.9"	"76.2"	"99.9"	"156.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5T0N5"	"Formin-binding protein 1-like OS=Homo sapiens OX=9606 GN=FNBP1L PE=1 SV=3"	"2"	"1"	"1"	"1"	"605"	"70.0"	"6.64"	""	"3.50"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00018, Pf00611"	"54874"	"ENSG00000137942"	"FNBP1L"	"hsa:54874; J3QSS4; Q5T0N5; Q5T0N6; Q6B097; Q6P653; Q6R4Q4; Q9NXG1"	""	"CDC42 GTPase cycle; RHOJ GTPase cycle; Clathrin-mediated endocytosis"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43824"	"Putative GTP-binding protein 6 OS=Homo sapiens OX=9606 GN=GTPBP6 PE=2 SV=4"	"3"	"1"	"2"	"1"	"516"	"56.9"	"9.42"	"368.87"	"3.49"	"1"	"1"	""	"other cell component"	"translation activity;other molecular function"	"Pf01926, Pf13167, Pf16360"	"8225"	"ENSG00000178605"	"GTPBP6"	"H0Y2S1; hsa:8225; O43824; Q53F77; Q5HYX8"	""	""	"0"	"0"	"8.0"	"7.1"	"7.1"	"5.0"	"10.4"	"5.5"	"9.9"	"11.4"	"22.1"	"48.5"	"58.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q06203"	"Amidophosphoribosyltransferase OS=Homo sapiens OX=9606 GN=PPAT PE=1 SV=1"	"2"	"1"	"1"	"1"	"517"	"57.4"	"6.76"	""	"3.48"	""	"1"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf00156, Pf13522"	"5471"	"ENSG00000128059"	"PPAT"	"hsa:5471; Q06203"	"Fluoropyrimidine activity; Metabolic reprogramming in colon cancer"	"Purine ribonucleoside monophosphate biosynthesis"	"3"	"0"	"3.3"	"3.3"	"3.6"	"4.4"	"0.0"	"0.0"	"3.5"	"7.8"	"11.6"	"25.5"	"87.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5T3I0"	"G patch domain-containing protein 4 OS=Homo sapiens OX=9606 GN=GPATCH4 PE=1 SV=2"	"4"	"1"	"2"	"1"	"446"	"50.4"	"9.63"	"460.65"	"3.48"	"1"	"1"	""	"nucleus"	""	"Pf01585"	""	""	"GPATCH4"	"Q5T3I0; Q5T3I1; Q6ZUE7; Q8IWG8; Q9NXH4"	""	""	"0"	"0"	"75.7"	"57.0"	"95.7"	"84.2"	"102.4"	"100.3"	"104.2"	"107.1"	"189.8"	"242.6"	"281.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82673"	"28S ribosomal protein S35, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS35 PE=1 SV=1"	"7"	"3"	"4"	"3"	"323"	"36.8"	"8.24"	"818.92"	"3.48"	"3"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf10213"	"60488"	"ENSG00000061794"	"MRPS35"	"hsa:60488; P82673; Q32LZ1; Q6P4C6; Q7L1M6; Q8NBP4; Q96AI0; Q9H044; Q9HC14; Q9P1R5"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"455.4"	"343.0"	"419.4"	"399.3"	"469.5"	"438.4"	"497.3"	"538.5"	"683.2"	"919.4"	"1331.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H444"	"Charged multivesicular body protein 4b OS=Homo sapiens OX=9606 GN=CHMP4B PE=1 SV=1"	"6"	"1"	"2"	"1"	"224"	"24.9"	"4.82"	"355.52"	"3.48"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf03357"	"128866"	"ENSG00000101421"	"CHMP4B"	"E1P5N4; hsa:128866; Q53ZD6; Q9H444"	""	"Sealing of the nuclear envelope (NE) by ESCRT-III; Budding and maturation of HIV virion; Endosomal Sorting Complex Required For Transport (ESCRT); HCMV Late Events; Late endosomal microautophagy; Macroautophagy; Pyroptosis; Translation of Replicase and Assembly of the Replication Transcription Complex; Translation of Replicase and Assembly of the Replication Transcription Complex"	"9"	"0"	"46.2"	"42.8"	"54.4"	"49.9"	"55.0"	"42.9"	"62.6"	"76.3"	"152.2"	"304.2"	"493.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NPB8"	"Glycerophosphocholine phosphodiesterase GPCPD1 OS=Homo sapiens OX=9606 GN=GPCPD1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"672"	"76.0"	"5.53"	"284.95"	"3.48"	"1"	"1"	"other metabolic processes;other biological processes"	"cytosol"	"other molecular function"	"Pf00686, Pf03009"	"56261"	"ENSG00000125772"	"GPCPD1"	"D3DW06; hsa:56261; Q9BQL8; Q9NPB8; Q9NUX0"	""	"Hydrolysis of LPC; Hydrolysis of LPE"	"2"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"2.8"	"5.4"	"43.9"	"89.4"	"125.1"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6FIF0"	"AN1-type zinc finger protein 6 OS=Homo sapiens OX=9606 GN=ZFAND6 PE=1 SV=2"	"9"	"2"	"3"	"2"	"208"	"22.5"	"7.20"	"671.11"	"3.47"	"2"	"1"	"cell organization and biogenesis;transport;other biological processes"	"cytosol"	"nucleic acid binding activity;other molecular function"	"Pf01428, Pf01754"	"54469"	"ENSG00000086666"	"ZFAND6"	"D3DW92; D3DW94; hsa:54469; O95792; Q6FIF0; Q9BQF7; Q9GZY3"	""	"Peroxisomal protein import"	"1"	"0"	"43.0"	"40.8"	"49.8"	"37.9"	"48.7"	"47.9"	"63.3"	"114.8"	"470.6"	"801.2"	"975.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NWU2"	"Glucose-induced degradation protein 8 homolog OS=Homo sapiens OX=9606 GN=GID8 PE=1 SV=1"	"5"	"1"	"1"	"1"	"228"	"26.7"	"4.97"	""	"3.47"	""	"1"	"cell-cell signaling;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf08513, Pf10607"	"54994"	"ENSG00000101193"	"GID8"	"E1P5I3; hsa:54994; Q8N5M5; Q9NWU2"	"Ciliary landscape"	""	"1"	"0"	"15.8"	"19.7"	"20.5"	"15.3"	"18.5"	"19.2"	"21.7"	"36.1"	"100.6"	"232.5"	"319.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NVT9"	"Armadillo repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=ARMC1 PE=1 SV=1"	"10"	"1"	"1"	"1"	"282"	"31.3"	"5.74"	""	"3.47"	""	"1"	"cell organization and biogenesis"	"other membranes;cytosol;mitochondrion"	"other molecular function"	"Pf00514"	"55156"	"ENSG00000104442"	"ARMC1"	"B4E2W7; hsa:55156; Q9H018; Q9H820; Q9NVT9"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q00325"	"Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=2"	"3"	"1"	"2"	"1"	"362"	"40.1"	"9.38"	"341.52"	"3.47"	"1"	"1"	"transport"	"plasma membrane;other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00153"	"5250"	"ENSG00000075415"	"SLC25A3"	"B3KS34; hsa:5250; Q00325; Q7Z7N7; Q96A03"	""	""	"0"	"0"	"16.5"	"18.3"	"18.6"	"14.2"	"17.1"	"19.0"	"22.8"	"38.4"	"84.1"	"137.0"	"200.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61970"	"Nuclear transport factor 2 OS=Homo sapiens OX=9606 GN=NUTF2 PE=1 SV=1"	"17"	"2"	"3"	"2"	"127"	"14.5"	"5.38"	"719.23"	"3.47"	"2"	"1"	"transport;other biological processes"	"other membranes;cytosol;nucleus"	"other molecular function"	"Pf02136"	"10204"	"ENSG00000102898"	"NUTF2"	"B2R4G7; hsa:10204; P13662; P61970; Q6IB67"	""	""	"0"	"0"	"68.3"	"126.5"	"90.5"	"91.8"	"91.0"	"61.9"	"93.1"	"164.2"	"241.3"	"387.2"	"346.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95721"	"Synaptosomal-associated protein 29 OS=Homo sapiens OX=9606 GN=SNAP29 PE=1 SV=1"	"4"	"1"	"2"	"1"	"258"	"29.0"	"5.81"	"280.33"	"3.46"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	""	"9342"	"ENSG00000099940"	"SNAP29"	"hsa:9342; O95721"	"Ciliary landscape; 22q11.2 copy number variation syndrome"	"Neutrophil degranulation; Intra-Golgi traffic"	"4"	"0"	"28.9"	"25.2"	"21.7"	"22.2"	"26.2"	"25.8"	"33.0"	"37.8"	"51.4"	"80.3"	"108.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BR76"	"Coronin-1B OS=Homo sapiens OX=9606 GN=CORO1B PE=1 SV=1"	"3"	"1"	"1"	"1"	"489"	"54.2"	"5.88"	""	"3.45"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400, Pf08953, Pf16300"	"57175"	"ENSG00000172725"	"CORO1B"	"B2RD45; hsa:57175; Q9BR76"	""	""	"0"	"0"	"12.6"	"11.8"	"12.7"	"11.3"	"11.9"	"10.6"	"18.3"	"25.7"	"55.1"	"172.5"	"368.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86YT6"	"E3 ubiquitin-protein ligase MIB1 OS=Homo sapiens OX=9606 GN=MIB1 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1006"	"110.1"	"6.92"	"263.58"	"3.45"	"1"	"1"	"protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00569, Pf06701, Pf12796, Pf13920, Pf18346"	"57534"	"ENSG00000101752"	"MIB1"	"B0YJ38; hsa:57534; Q2TB37; Q68D01; Q6YI51; Q86YT6; Q8NBY0; Q8TCB5; Q8TCL7; Q9P2M3"	"Genes related to primary cilium development (based on CRISPR)"	"Activated NOTCH1 Transmits Signal to the Nucleus; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; NOTCH2 Activation and Transmission of Signal to the Nucleus; NOTCH3 Activation and Transmission of Signal to the Nucleus"	"7"	"0"	"16.8"	"22.0"	"25.8"	"16.0"	"24.2"	"19.5"	"25.7"	"37.3"	"55.4"	"126.4"	"193.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HC62"	"Sentrin-specific protease 2 OS=Homo sapiens OX=9606 GN=SENP2 PE=1 SV=3"	"2"	"1"	"2"	"1"	"589"	"67.8"	"9.48"	"281.57"	"3.45"	"1"	"1"	"cell-cell signaling;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;nucleus"	"other molecular function"	"Pf02902"	"59343"	"ENSG00000163904"	"SENP2"	"B4DQ42; hsa:59343; Q8IW97; Q96SR2; Q9HC62; Q9P2L5"	"lncRNA in canonical Wnt signaling and colorectal cancer; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Pleural mesothelioma"	"SUMO is proteolytically processed"	"5"	"0"	"127.5"	"91.9"	"122.1"	"120.5"	"126.8"	"132.9"	"150.8"	"169.5"	"262.6"	"342.5"	"473.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7L266"	"Isoaspartyl peptidase/L-asparaginase OS=Homo sapiens OX=9606 GN=ASRGL1 PE=1 SV=2"	"3"	"1"	"1"	"1"	"308"	"32.0"	"6.24"	""	"3.44"	""	"1"	"protein metabolism;other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf01112"	"80150"	"ENSG00000162174"	"ASRGL1"	"B2R7Q0; hsa:80150; Q567Q4; Q6P1P0; Q7L266; Q8NI34; Q9H6F7"	""	"Phenylalanine metabolism"	"1"	"0"	"8.6"	"8.0"	"11.7"	"8.4"	"13.7"	"8.6"	"12.5"	"24.1"	"57.2"	"155.7"	"298.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16626"	"Male-enhanced antigen 1 OS=Homo sapiens OX=9606 GN=MEA1 PE=1 SV=2"	"7"	"1"	"2"	"1"	"185"	"19.9"	"4.22"	"343.22"	"3.44"	"1"	"1"	"developmental processes;other biological processes"	"other cell component"	""	"Pf06910"	"4201"	"ENSG00000124733"	"MEA1"	"hsa:4201; Q16626; Q5TC36; Q9BV01"	""	""	"0"	"0"	"62.3"	"49.1"	"65.6"	"58.2"	"64.1"	"62.4"	"70.1"	"81.3"	"113.4"	"168.0"	"203.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TF71"	"Monocarboxylate transporter 10 OS=Homo sapiens OX=9606 GN=SLC16A10 PE=1 SV=1"	"3"	"1"	"2"	"1"	"515"	"55.5"	"7.69"	"454.16"	"3.44"	"1"	"1"	"cell-cell signaling;other metabolic processes;transport"	"plasma membrane;other membranes;other cell component"	"transporter activity"	"Pf07690"	"117247"	"ENSG00000112394"	"SLC16A10"	"B3KWY0; hsa:117247; Q6ZMG0; Q8TF71; Q8WVI5"	"Thyroid hormones production and peripheral downstream signaling effects; Proximal tubule transport"	"Amino acid transport across the plasma membrane"	"3"	"0"	"21.2"	"17.4"	"12.7"	"15.8"	"12.1"	"19.7"	"20.6"	"28.7"	"71.9"	"76.4"	"120.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15678"	"Tyrosine-protein phosphatase non-receptor type 14 OS=Homo sapiens OX=9606 GN=PTPN14 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1187"	"135.2"	"8.31"	"315.63"	"3.43"	"1"	"1"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00102, Pf00373, Pf09379, Pf09380"	"5784"	"ENSG00000152104"	"PTPN14"	"hsa:5784; Q15678; Q5VSI0"	"VEGFA-VEGFR2 signaling"	"Interleukin-37 signaling"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9GZM8"	"Nuclear distribution protein nudE-like 1 OS=Homo sapiens OX=9606 GN=NDEL1 PE=1 SV=1"	"4"	"1"	"2"	"1"	"345"	"38.4"	"5.24"	"541.63"	"3.43"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf04880"	"81565"	"ENSG00000166579"	"NDEL1"	"B3KP93; D3DTS0; hsa:81565; J3QT32; Q86T80; Q8TAR7; Q9GZM8; Q9UH50"	"Neurogenesis regulation in the olfactory epithelium; PAFAH1B1 copy number variation"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"8"	"0"	"25.9"	"27.4"	"32.4"	"27.1"	"26.1"	"21.3"	"34.1"	"53.5"	"92.0"	"161.0"	"227.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23786"	"Carnitine O-palmitoyltransferase 2, mitochondrial OS=Homo sapiens OX=9606 GN=CPT2 PE=1 SV=2"	"2"	"1"	"2"	"1"	"658"	"73.7"	"8.18"	"351.08"	"3.43"	"1"	"1"	"other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf00755"	"1376"	"ENSG00000157184"	"CPT2"	"B2R6S0; hsa:1376; P23786; Q5SW68; Q9BQ26"	"Fatty acid beta-oxidation; PPAR-alpha pathway; Nuclear receptors meta-pathway; Mitochondrial long chain fatty acid beta-oxidation; PPAR signaling pathway; Thermogenesis; Mitochondrial fatty acid oxidation disorders"	"PPARA activates gene expression; Carnitine metabolism"	"9"	"0"	"17.2"	"17.5"	"16.4"	"12.3"	"23.2"	"19.5"	"17.1"	"21.5"	"32.3"	"59.7"	"97.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P29590"	"Protein PML OS=Homo sapiens OX=9606 GN=PML PE=1 SV=3"	"1"	"1"	"2"	"1"	"882"	"97.5"	"6.21"	"317.41"	"3.43"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00643, Pf12126"	"5371"	"ENSG00000140464"	"PML"	"E9PBR7; hsa:5371; P29590; P29591; P29592; P29593; Q00755; Q15959; Q59FP9; Q8WUA0; Q96S41; Q9BPW2; Q9BWP7; Q9BZX6; Q9BZX7; Q9BZX8; Q9BZX9; Q9BZY0; Q9BZY2; Q9BZY3"	"miRNA regulation of DNA damage response; Wnt/beta-catenin signaling pathway in leukemia; p53 transcriptional gene network; DNA damage response"	"HCMV Early Events; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Interferon gamma signaling; Regulation of TP53 Activity through Acetylation; Regulation of PTEN localization; Regulation of RUNX1 Expression and Activity"	"11"	"0"	"8.2"	"9.7"	"8.2"	"9.4"	"9.6"	"7.8"	"9.0"	"15.8"	"18.0"	"31.7"	"45.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N1B4"	"Vacuolar protein sorting-associated protein 52 homolog OS=Homo sapiens OX=9606 GN=VPS52 PE=1 SV=1"	"2"	"1"	"2"	"1"	"723"	"82.2"	"5.99"	"337.37"	"3.43"	"1"	"1"	"transport;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf04129"	"6293"	"ENSG00000206286; ENSG00000223501; ENSG00000224455; ENSG00000225590; ENSG00000228425; ENSG00000236014"	"VPS52"	"A2BF38; B0UZZ4; B4DNI9; hsa:6293; Q53GR4; Q5JPA0; Q5SQW1; Q8IUN6; Q8N1B4; Q9NPT5"	""	"Retrograde transport at the Trans-Golgi-Network"	"1"	"0"	"15.3"	"12.1"	"18.3"	"14.1"	"18.1"	"17.6"	"16.3"	"30.3"	"43.1"	"62.6"	"79.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y248"	"DNA replication complex GINS protein PSF2 OS=Homo sapiens OX=9606 GN=GINS2 PE=1 SV=1"	"7"	"1"	"2"	"1"	"185"	"21.4"	"5.44"	"255.15"	"3.43"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus"	""	"Pf05916"	"51659"	"ENSG00000131153"	"GINS2"	"D3DUM5; hsa:51659; Q6IAG9; Q9Y248"	""	"Unwinding of DNA"	"1"	"0"	"41.4"	"25.3"	"49.8"	"45.3"	"41.7"	"41.0"	"57.3"	"57.1"	"109.4"	"185.5"	"238.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96AY3"	"Peptidyl-prolyl cis-trans isomerase FKBP10 OS=Homo sapiens OX=9606 GN=FKBP10 PE=1 SV=1"	"2"	"1"	"2"	"1"	"582"	"64.2"	"5.62"	"370.13"	"3.42"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes"	"other membranes;mitochondrion;ER/Golgi"	"other molecular function"	"Pf00254, Pf13202"	"60681"	"ENSG00000141756"	"FKBP10"	"hsa:60681; Q7Z3R4; Q96AY3; Q9H3N3; Q9H6J3; Q9H6N5; Q9UF89"	"Type I collagen synthesis in the context of osteogenesis imperfecta"	""	"1"	"0"	"22.8"	"30.8"	"23.2"	"22.8"	"20.2"	"21.2"	"22.7"	"27.0"	"49.7"	"84.4"	"113.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99442"	"Translocation protein SEC62 OS=Homo sapiens OX=9606 GN=SEC62 PE=1 SV=1"	"3"	"1"	"1"	"1"	"399"	"45.8"	"7.12"	""	"3.42"	""	"1"	"transport"	"other membranes;ER/Golgi"	"other molecular function"	"Pf03839"	"7095"	"ENSG00000008952"	"SEC62"	"D3DNQ0; hsa:7095; O00682; O00729; Q99442"	""	""	"0"	"0"	"36.9"	"27.4"	"39.0"	"37.5"	"37.8"	"44.7"	"45.7"	"50.1"	"239.7"	"486.3"	"720.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UER7"	"Death domain-associated protein 6 OS=Homo sapiens OX=9606 GN=DAXX PE=1 SV=2"	"2"	"1"	"2"	"1"	"740"	"81.3"	"4.87"	"512.93"	"3.42"	"1"	"1"	"cell organization and biogenesis;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf03344"	"1616"	"ENSG00000204209; ENSG00000206206; ENSG00000206279; ENSG00000227046; ENSG00000231617"	"DAXX"	"B4E1I3; F5ANJ6; F5ANJ7; F5H082; hsa:1616; O14747; O15141; O15208; Q5STK9; Q9BWI3; Q9UER7"	"Androgen receptor signaling pathway; Amyotrophic lateral sclerosis (ALS); Fas ligand pathway and stress induction of heat shock proteins; MAPK signaling pathway; p38 MAPK signaling pathway"	"HCMV Early Events; Inhibition of DNA recombination at telomere; SUMOylation of transcription cofactors; Regulation of TP53 Degradation; Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations; Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations"	"11"	"0"	"8.6"	"12.8"	"12.1"	"10.6"	"8.8"	"11.2"	"12.1"	"23.5"	"39.1"	"79.5"	"88.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q70E73"	"Ras-associated and pleckstrin homology domains-containing protein 1 OS=Homo sapiens OX=9606 GN=RAPH1 PE=1 SV=3"	"1"	"1"	"2"	"1"	"1250"	"135.2"	"8.85"	"444.21"	"3.42"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	""	"Pf00169, Pf00788"	"65059"	"ENSG00000173166"	"RAPH1"	"hsa:65059; Q70E73; Q96Q37; Q9C0I2"	""	""	"0"	"0"	"0.0"	"2.3"	"0.0"	"0.0"	"3.9"	"2.0"	"1.8"	"6.2"	"23.2"	"42.5"	"48.1"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z745"	"Maestro heat-like repeat-containing protein family member 2B OS=Homo sapiens OX=9606 GN=MROH2B PE=2 SV=3"	"1"	"1"	"1"	"1"	"1585"	"180.7"	"6.28"	""	"3.42"	""	"1"	"signal transduction;other biological processes"	"cytoskeleton;other cell component"	""	""	"133558"	"ENSG00000171495"	"MROH2B"	"hsa:133558; Q68DM1; Q7Z4U4; Q7Z745; Q8N7X3"	""	""	"0"	"0"	"296.3"	"279.5"	"273.3"	"255.5"	"267.8"	"269.2"	"322.1"	"349.1"	"381.5"	"540.0"	"856.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y6G3"	"39S ribosomal protein L42, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL42 PE=1 SV=1"	"16"	"1"	"1"	"1"	"142"	"16.7"	"8.35"	""	"3.42"	""	"1"	"protein metabolism;other metabolic processes"	"plasma membrane;other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf10210"	"28977"	"ENSG00000198015"	"MRPL42"	"hsa:28977; Q6FID1; Q96Q48; Q9P0S1; Q9Y6G3"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"9.9"	"10.0"	"9.6"	"11.7"	"9.8"	"12.6"	"9.4"	"13.3"	"24.0"	"40.7"	"60.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60826"	"Coiled-coil domain-containing protein 22 OS=Homo sapiens OX=9606 GN=CCDC22 PE=1 SV=1"	"2"	"1"	"2"	"1"	"627"	"70.7"	"6.74"	"451.54"	"3.40"	"1"	"1"	"transport;other biological processes"	"cytosol;cytoskeleton;nucleus;other cytoplasmic organelle"	"other molecular function"	"Pf05667"	"28952"	"ENSG00000101997"	"CCDC22"	"A8K7G1; hsa:28952; O60826"	""	"Neddylation"	"1"	"0"	"23.9"	"28.6"	"27.0"	"25.0"	"28.4"	"27.9"	"40.9"	"51.1"	"85.8"	"189.9"	"298.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NUP7"	"tRNA:m(4)X modification enzyme TRM13 homolog OS=Homo sapiens OX=9606 GN=TRMT13 PE=1 SV=2"	"2"	"1"	"2"	"1"	"481"	"54.2"	"8.09"	"397.56"	"3.40"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	""	"other molecular function"	"Pf05206, Pf05253, Pf11722"	"54482"	"ENSG00000122435"	"TRMT13"	"hsa:54482; Q5VVL0; Q9NUP7; Q9NW65"	""	"tRNA modification in the nucleus and cytosol"	"1"	"0"	"2.6"	"3.4"	"4.3"	"2.3"	"2.8"	"4.1"	"4.9"	"6.7"	"33.3"	"56.9"	"68.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61764"	"Syntaxin-binding protein 1 OS=Homo sapiens OX=9606 GN=STXBP1 PE=1 SV=1"	"3"	"1"	"2"	"1"	"594"	"67.5"	"6.96"	"433.36"	"3.40"	"1"	"1"	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00995"	"6812"	"ENSG00000136854"	"STXBP1"	"B1AM97; hsa:6812; P61764; Q28208; Q62759; Q64320; Q68CM6; Q96TG8"	"Synaptic vesicle pathway; Rett syndrome causing genes; EGF/EGFR signaling pathway; Insulin signaling; 15q11q13 copy number variation"	"Regulation of insulin secretion; Neurexins and neuroligins"	"7"	"0"	"7.6"	"9.0"	"10.0"	"9.1"	"7.3"	"9.3"	"13.8"	"16.0"	"48.4"	"116.4"	"157.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N2Z9"	"Centromere protein S OS=Homo sapiens OX=9606 GN=CENPS PE=1 SV=1"	"9"	"1"	"2"	"1"	"138"	"15.9"	"6.05"	"443.65"	"3.40"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf15630"	"100526739; 378708"	"ENSG00000175279"	"CENPS"	"hsa:100526739; hsa:378708; Q8N2Z9; Q8NFE5; Q8NFG5"	"DNA repair pathways, full network"	"Fanconi Anemia Pathway; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Deposition of new CENPA-containing nucleosomes at the centromere"	"9"	"0"	"25.6"	"20.7"	"28.7"	"23.6"	"23.0"	"23.2"	"31.1"	"40.7"	"111.5"	"304.1"	"477.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96F86"	"Enhancer of mRNA-decapping protein 3 OS=Homo sapiens OX=9606 GN=EDC3 PE=1 SV=1"	"3"	"1"	"2"	"1"	"508"	"56.0"	"7.11"	"333.99"	"3.39"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03853, Pf09532, Pf12701, Pf16598"	"80153"	"ENSG00000179151"	"EDC3"	"B3KPH0; D3DW61; hsa:80153; Q96F86; Q9H797"	""	"mRNA decay by 5' to 3' exoribonuclease"	"1"	"0"	"31.3"	"21.4"	"31.9"	"29.6"	"32.6"	"34.2"	"35.5"	"44.7"	"76.4"	"168.0"	"390.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UPN9"	"E3 ubiquitin-protein ligase TRIM33 OS=Homo sapiens OX=9606 GN=TRIM33 PE=1 SV=3"	"1"	"1"	"1"	"1"	"1127"	"122.5"	"6.67"	""	"3.39"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00439, Pf00628, Pf00643, Pf13445"	"51592"	"ENSG00000197323"	"TRIM33"	"hsa:51592; O95855; Q5TG72; Q5TG73; Q5TG74; Q9C017; Q9UJ79; Q9UPN9"	"Ectoderm differentiation"	"Downregulation of SMAD2/3:SMAD4 transcriptional activity; Germ layer formation at gastrulation"	"3"	"0"	"26.7"	"25.7"	"25.1"	"23.8"	"30.9"	"14.6"	"21.5"	"34.7"	"48.1"	"68.4"	"108.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IYB7"	"DIS3-like exonuclease 2 OS=Homo sapiens OX=9606 GN=DIS3L2 PE=1 SV=4"	"2"	"1"	"1"	"1"	"885"	"99.2"	"6.10"	""	"3.39"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00773, Pf17216, Pf17849, Pf17877"	"129563"	"ENSG00000144535"	"DIS3L2"	"hsa:129563; Q53S79; Q580W6; Q5XKH0; Q69YG5; Q6AW99; Q7Z4T6; Q8IYB7; Q8N9K9"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12846"	"Syntaxin-4 OS=Homo sapiens OX=9606 GN=STX4 PE=1 SV=2"	"4"	"1"	"2"	"1"	"297"	"34.2"	"6.28"	"294.23"	"3.38"	"1"	"1"	"cell organization and biogenesis;stress response;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00804, Pf05739"	"6810"	"ENSG00000103496"	"STX4"	"A8MXY0; hsa:6810; Q12846; Q15525; Q6FHE8"	"Insulin signaling"	"ER-Phagosome pathway; Translocation of SLC2A4 (GLUT4) to the plasma membrane; trans-Golgi Network Vesicle Budding; Disinhibition of SNARE formation; Other interleukin signaling"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q03701"	"CCAAT/enhancer-binding protein zeta OS=Homo sapiens OX=9606 GN=CEBPZ PE=1 SV=3"	"1"	"1"	"2"	"1"	"1054"	"120.9"	"5.94"	"330.04"	"3.38"	"1"	"1"	"other biological processes"	"nucleus"	"other molecular function"	"Pf03914"	"10153"	"ENSG00000115816"	"CEBPZ"	"hsa:10153; Q03701; Q8NE75"	"Gastric cancer network 2"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22087"	"rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2"	"8"	"2"	"3"	"2"	"321"	"33.8"	"10.18"	"676.72"	"3.38"	"2"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf01269"	"2091"	"ENSG00000105202; ENSG00000280548"	"FBL"	"B5BUE8; hsa:2091; O75259; P22087; Q6IAT5; Q9UPI6"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"134.7"	"117.4"	"137.2"	"112.5"	"122.3"	"101.9"	"160.6"	"160.6"	"203.9"	"297.7"	"543.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15057"	"Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ACAP2 PE=1 SV=3"	"2"	"1"	"2"	"1"	"778"	"88.0"	"6.80"	"300.43"	"3.38"	"1"	"1"	"transport;other biological processes"	"other membranes;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf01412, Pf12796, Pf16746"	"23527"	"ENSG00000114331"	"ACAP2"	"A8K2V4; hsa:23527; Q15057; Q8N5Z8; Q9UQR3"	""	""	"0"	"0"	"30.0"	"18.9"	"27.9"	"22.4"	"22.0"	"30.4"	"37.5"	"50.3"	"118.2"	"211.2"	"344.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H0E2"	"Toll-interacting protein OS=Homo sapiens OX=9606 GN=TOLLIP PE=1 SV=1"	"3"	"1"	"2"	"1"	"274"	"30.3"	"5.97"	"393.54"	"3.37"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00168, Pf02845"	"54472"	"ENSG00000078902"	"TOLLIP"	"B3KXC6; hsa:54472; Q9H0E2; Q9H9E6; Q9UJ69"	"IL-1 signaling pathway; Interleukin-1 (IL-1) structural pathway; Toll-like receptor signaling related to MyD88; Signal transduction through IL1R; Toll-like receptor signaling pathway"	"Neutrophil degranulation; Interleukin-1 signaling"	"7"	"0"	"36.6"	"40.4"	"51.9"	"46.5"	"52.1"	"56.1"	"42.0"	"69.1"	"233.8"	"435.5"	"580.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q70Z53"	"Protein FRA10AC1 OS=Homo sapiens OX=9606 GN=FRA10AC1 PE=1 SV=3"	"3"	"1"	"2"	"1"	"315"	"37.5"	"8.10"	"362.82"	"3.37"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf09725"	"118924"	"ENSG00000148690"	"FRA10AC1"	"C9JCR4; C9JCR5; C9JMY4; hsa:118924; Q70Z49; Q70Z50; Q70Z51; Q70Z52; Q70Z53; Q8N293; Q8WVH5; Q96JQ8"	""	""	"0"	"0"	"6.5"	"4.6"	"4.2"	"5.6"	"3.7"	"5.3"	"8.9"	"12.8"	"27.7"	"38.9"	"36.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H0U9"	"Testis-specific Y-encoded-like protein 1 OS=Homo sapiens OX=9606 GN=TSPYL1 PE=1 SV=3"	"3"	"1"	"2"	"1"	"437"	"49.2"	"5.45"	"445.13"	"3.37"	"1"	"1"	"cell organization and biogenesis"	"nucleus;other cell component"	"other molecular function"	"Pf00956"	"7259"	"ENSG00000189241"	"TSPYL1"	"hsa:7259; O75885; Q5TFE6; Q9H0U9"	"Sudden infant death syndrome (SIDS) susceptibility pathways"	""	"1"	"0"	"20.0"	"9.0"	"17.2"	"17.1"	"15.6"	"16.1"	"19.9"	"23.5"	"26.5"	"24.0"	"31.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5NDL2"	"EGF domain-specific O-linked N-acetylglucosamine transferase OS=Homo sapiens OX=9606 GN=EOGT PE=1 SV=1"	"2"	"1"	"1"	"1"	"527"	"62.0"	"7.05"	""	"3.36"	""	"1"	"protein metabolism;other metabolic processes"	"ER/Golgi"	"other molecular function"	"Pf04577"	"285203"	"ENSG00000163378"	"EOGT"	"A8K2U1; B4DFH5; hsa:285203; L7X1M5; Q5NDL2; Q6MZY0; Q6P985; Q6ZTV0"	"Genetic causes of porto-sinusoidal vascular disease"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00567"	"Nucleolar protein 56 OS=Homo sapiens OX=9606 GN=NOP56 PE=1 SV=4"	"3"	"2"	"3"	"2"	"594"	"66.0"	"9.19"	"658.65"	"3.36"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01798, Pf08156"	"10528"	"ENSG00000101361"	"NOP56"	"hsa:10528; O00567; Q2M3T6; Q9NQ05"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol; Association of TriC/CCT with target proteins during biosynthesis"	"3"	"0"	"42.0"	"27.9"	"50.8"	"32.0"	"43.9"	"45.8"	"44.1"	"67.4"	"188.0"	"165.2"	"141.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NZZ3"	"Charged multivesicular body protein 5 OS=Homo sapiens OX=9606 GN=CHMP5 PE=1 SV=1"	"7"	"1"	"1"	"1"	"219"	"24.6"	"4.83"	""	"3.36"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	""	"Pf03357"	"51510"	"ENSG00000086065"	"CHMP5"	"B2RD95; B4DIR6; hsa:51510; Q5VXW2; Q96AV2; Q9HB68; Q9NYS4; Q9NZZ3; Q9Y323"	"Ferroptosis"	"Budding and maturation of HIV virion; Endosomal Sorting Complex Required For Transport (ESCRT)"	"3"	"0"	"22.1"	"18.4"	"33.0"	"23.4"	"29.2"	"26.1"	"30.8"	"38.4"	"62.1"	"113.1"	"166.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BVQ7"	"Spermatogenesis-associated protein 5-like protein 1 OS=Homo sapiens OX=9606 GN=SPATA5L1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"753"	"80.7"	"8.09"	"337.86"	"3.36"	"1"	"1"	"other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf17862"	"79029"	"ENSG00000171763"	"AFG2B"	"C9JHR5; hsa:79029; Q9BVQ7; Q9H8W7; Q9HA41"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N5W9"	"Refilin-B OS=Homo sapiens OX=9606 GN=RFLNB PE=1 SV=1"	"6"	"1"	"2"	"1"	"214"	"22.9"	"5.44"	"254.10"	"3.36"	"1"	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf15068"	"359845"	"ENSG00000183688"	"RFLNB"	"hsa:359845; Q8N5W9"	""	""	"0"	"0"	"30.2"	"27.9"	"32.8"	"30.8"	"42.7"	"37.2"	"46.8"	"46.2"	"80.0"	"172.6"	"246.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q0VD83"	"Apolipoprotein B receptor OS=Homo sapiens OX=9606 GN=APOBR PE=1 SV=3"	"3"	"1"	"1"	"1"	"1097"	"115.6"	"4.40"	""	"3.36"	""	"1"	"other metabolic processes;transport"	"non-structural extracellular;plasma membrane;other membranes"	"other molecular function"	""	"55911"	"ENSG00000184730"	"APOBR"	"H3BU97; hsa:55911; Q0VD81; Q0VD83; Q8NC15; Q9NPJ9"	""	"VLDL clearance"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94880"	"PHD finger protein 14 OS=Homo sapiens OX=9606 GN=PHF14 PE=1 SV=2"	"1"	"1"	"2"	"1"	"888"	"100.0"	"5.33"	"417.31"	"3.35"	"1"	"1"	""	""	"other molecular function"	"Pf00628, Pf13832"	"463265"	"ENSPTRG00000018935"	"PHF14"	"A0A2J8MED2; A0A6D2XU20; H2RCM0; ptr:463265"	""	""	"0"	"0"	"16.1"	"16.2"	"14.0"	"14.2"	"13.3"	"13.9"	"15.8"	"25.8"	"32.8"	"54.4"	"72.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H7Z3"	"Nuclear exosome regulator NRDE2 OS=Homo sapiens OX=9606 GN=NRDE2 PE=1 SV=3"	"2"	"3"	"4"	"3"	"1164"	"132.6"	"7.68"	"895.05"	"3.35"	"3"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus"	""	"Pf08424"	"55051"	"ENSG00000119720"	"NRDE2"	"B4DH71; hsa:55051; Q4G0A7; Q9H7Z3; Q9NWH6"	""	""	"0"	"0"	"64.6"	"74.2"	"62.1"	"60.8"	"67.5"	"57.1"	"78.3"	"108.9"	"362.9"	"418.6"	"447.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13501"	"Sequestosome-1 OS=Homo sapiens OX=9606 GN=SQSTM1 PE=1 SV=1"	"5"	"1"	"1"	"1"	"440"	"47.7"	"5.22"	""	"3.35"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;kinase activity;other molecular function"	"Pf00564, Pf00569, Pf16577"	"8878"	"ENSG00000161011; ENSG00000284099"	"SQSTM1"	"A6NFN7; B2R661; B3KUW5; hsa:8878; Q13446; Q13501; Q9BUV7; Q9BVS6; Q9UEU1"	"IL-1 signaling pathway; RANKL/RANK signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Apoptosis-related network due to altered Notch3 in ovarian cancer; Nuclear receptors meta-pathway; NRF2 pathway; Interleukin-1 induced activation of NF-kB; Clear cell renal cell carcinoma pathways; CAMKK2 pathway; 7q11.23 copy number variation syndrome; Opioid receptor pathways; Clock-controlled autophagy in bone metabolism; Autophagy in pancreatic ductal adenocarcinoma"	"Neddylation; Interleukin-1 signaling; Signaling by ALK fusions and activated point mutants; p75NTR recruits signalling complexes; NF-kB is activated and signals survival; Nuclear events mediated by NFE2L2; PINK1-PRKN Mediated Mitophagy; NRIF signals cell death from the nucleus; Pexophagy"	"23"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q13464"	"Rho-associated protein kinase 1 OS=Homo sapiens OX=9606 GN=ROCK1 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1354"	"158.1"	"5.90"	"272.81"	"3.35"	"1"	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"enzyme regulator activity;cytoskeletal activity;kinase activity;other molecular function"	"Pf00069, Pf08912"	"6093"	"ENSG00000067900"	"ROCK1"	"B0YJ91; hsa:6093; Q13464; Q2KHM4; Q59GZ4"	"Androgen receptor signaling pathway; MicroRNAs in cardiomyocyte hypertrophy; Integrin-mediated cell adhesion; Leptin signaling pathway; Microtubule cytoskeleton regulation; Pathogenic Escherichia coli infection; AGE/RAGE pathway; Focal adhesion; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; EGF/EGFR signaling pathway; Gastrin signaling pathway; mBDNF and proBDNF regulation of GABA neurotransmission; MAP3K1 role in promoting and blocking gonadal determination; Airway smooth muscle cell contraction; RAS and bradykinin pathways in COVID-19; Regulation of actin cytoskeleton; GDNF signaling; G13 signaling pathway"	"RND3 GTPase cycle; RHOBTB1 GTPase cycle; RHOA GTPase cycle; G alpha (12/13) signalling events; Neutrophil degranulation; VEGFA-VEGFR2 Pathway; EPHB-mediated forward signaling; Potential therapeutics for SARS; RHOC GTPase cycle; RHOB GTPase cycle; EPHA-mediated growth cone collapse; Sema4D induced cell migration and growth-cone collapse; RHO GTPases Activate ROCKs; RHOH GTPase cycle; Apoptotic cleavage of cellular proteins"	"34"	"0"	"5.3"	"5.0"	"6.8"	"7.2"	"9.2"	"4.6"	"9.3"	"11.6"	"25.4"	"90.5"	"218.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13144"	"Translation initiation factor eIF-2B subunit epsilon OS=Homo sapiens OX=9606 GN=EIF2B5 PE=1 SV=3"	"2"	"1"	"2"	"1"	"721"	"80.3"	"5.08"	"415.45"	"3.35"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf02020"	"8893"	"ENSG00000145191"	"EIF2B5"	"hsa:8893; Q13144; Q541Z1; Q96D04"	"Translation factors; MicroRNAs in cardiomyocyte hypertrophy; DYRK1A involvement regarding cell proliferation in brain development; Primary ovarian insufficiency"	"Recycling of eIF2:GDP"	"5"	"0"	"9.7"	"16.2"	"13.8"	"9.9"	"13.1"	"17.1"	"15.4"	"25.8"	"41.3"	"98.9"	"149.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14737"	"Programmed cell death protein 5 OS=Homo sapiens OX=9606 GN=PDCD5 PE=1 SV=3"	"9"	"1"	"2"	"1"	"125"	"14.3"	"6.04"	"295.03"	"3.35"	"1"	"1"	"other biological processes"	"cytosol;nucleus"	"enzyme regulator activity;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf01984"	"9141"	"ENSG00000105185"	"PDCD5"	"B4DE64; hsa:9141; O14737; Q53YC9; Q6IB70"	""	""	"0"	"0"	"26.1"	"29.8"	"34.6"	"28.8"	"30.1"	"32.6"	"43.0"	"55.3"	"81.6"	"208.3"	"404.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96G01"	"Protein bicaudal D homolog 1 OS=Homo sapiens OX=9606 GN=BICD1 PE=1 SV=3"	"1"	"1"	"1"	"1"	"975"	"110.7"	"5.81"	""	"3.35"	""	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf09730"	"636"	"ENSG00000151746"	"BICD1"	"A8K2C3; F8W113; hsa:636; O43892; O43893; Q96G01"	""	"COPI-independent Golgi-to-ER retrograde traffic"	"1"	"0"	"2.4"	"5.4"	"5.5"	"4.0"	"2.8"	"4.1"	"4.4"	"7.6"	"26.2"	"104.9"	"137.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2X7"	"ARF GTPase-activating protein GIT1 OS=Homo sapiens OX=9606 GN=GIT1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"761"	"84.3"	"6.80"	"488.12"	"3.35"	"1"	"1"	"transport;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;mitochondrion;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf01412, Pf08518, Pf12205, Pf12796, Pf16559"	"28964"	"ENSG00000108262"	"GIT1"	"B4DGU9; B4DSV3; hsa:28964; Q86SS0; Q9BRJ4; Q9Y2X7"	"CAMKK2 pathway; Regulation of actin cytoskeleton"	"RHOJ GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOV GTPase cycle; RHOU GTPase cycle; Ephrin signaling; Activation of RAC1 downstream of NMDARs"	"12"	"0"	"23.2"	"22.8"	"26.5"	"24.6"	"27.8"	"26.1"	"25.2"	"34.1"	"87.0"	"274.7"	"394.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y570"	"Protein phosphatase methylesterase 1 OS=Homo sapiens OX=9606 GN=PPME1 PE=1 SV=3"	"3"	"1"	"2"	"1"	"386"	"42.3"	"5.97"	"376.97"	"3.34"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes"	"nucleus"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf12697"	"51400"	"ENSG00000214517"	"PPME1"	"B3KMU6; B5MEE7; hsa:51400; J3QT22; Q8WYG8; Q9NVT5; Q9UI18; Q9Y570"	""	"Cyclin A/B1/B2 associated events during G2/M transition"	"1"	"0"	"16.3"	"13.8"	"14.6"	"12.0"	"9.2"	"14.9"	"21.0"	"21.9"	"50.5"	"95.0"	"283.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96RS6"	"NudC domain-containing protein 1 OS=Homo sapiens OX=9606 GN=NUDCD1 PE=1 SV=2"	"4"	"1"	"1"	"1"	"583"	"66.7"	"5.11"	""	"3.34"	""	"1"	"other biological processes"	"cytosol;nucleus"	""	"Pf04969"	"84955"	"ENSG00000120526"	"NUDCD1"	"B4DVX6; hsa:84955; Q4G130; Q8NDQ5; Q8NG18; Q96RS6; Q96SI4; Q9BVR5"	""	""	"0"	"0"	"14.4"	"11.2"	"29.9"	"23.9"	"25.5"	"17.7"	"30.0"	"37.2"	"72.6"	"156.3"	"233.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H8H2"	"Probable ATP-dependent RNA helicase DDX31 OS=Homo sapiens OX=9606 GN=DDX31 PE=1 SV=2"	"2"	"1"	"2"	"1"	"851"	"94.0"	"9.99"	"400.08"	"3.34"	"1"	"1"	"other biological processes"	"ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271, Pf13959"	"64794"	"ENSG00000125485"	"DDX31"	"hsa:64794; Q5K6N2; Q5K6N3; Q5K6N4; Q5VZJ4; Q5VZJ9; Q96E91; Q96NY2; Q96SX5; Q9H5K6; Q9H8H2"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IVD9"	"NudC domain-containing protein 3 OS=Homo sapiens OX=9606 GN=NUDCD3 PE=1 SV=3"	"4"	"1"	"2"	"1"	"361"	"40.8"	"5.25"	"252.75"	"3.34"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;other cell component"	"other molecular function"	"Pf04969, Pf14050"	"23386"	"ENSG00000015676"	"NUDCD3"	"hsa:23386; Q8IVD9; Q9BTI3; Q9H7W9; Q9UPT4"	""	""	"0"	"0"	"13.4"	"19.1"	"18.2"	"19.8"	"22.7"	"18.0"	"19.9"	"24.9"	"39.3"	"78.9"	"46.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00193"	"Small acidic protein OS=Homo sapiens OX=9606 GN=SMAP PE=1 SV=1"	"13"	"2"	"3"	"2"	"183"	"20.3"	"4.72"	"828.66"	"3.34"	"2"	"1"	""	""	""	"Pf15477"	"10944"	"ENSG00000110696"	"SMAP"	"B2RD28; hsa:10944; O00193"	""	""	"0"	"0"	"452.1"	"405.9"	"455.5"	"413.9"	"434.1"	"480.3"	"536.5"	"546.4"	"573.2"	"641.4"	"852.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BSJ2"	"Gamma-tubulin complex component 2 OS=Homo sapiens OX=9606 GN=TUBGCP2 PE=1 SV=2"	"1"	"1"	"2"	"1"	"902"	"102.5"	"6.84"	"339.98"	"3.32"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes"	"cytosol;cytoskeleton;nucleus"	"cytoskeletal activity"	"Pf04130, Pf17681"	"10844"	"ENSG00000130640"	"TUBGCP2"	"B4DM18; B7ZKL8; F5H4E0; F5H4L0; hsa:10844; O43632; Q5VWX7; Q9BSJ2"	"Prader-Willi and Angelman syndrome; 15q11.2 copy number variation syndrome"	"Recruitment of NuMA to mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes"	"4"	"0"	"10.3"	"10.8"	"14.6"	"13.9"	"16.8"	"10.5"	"16.3"	"23.9"	"64.0"	"135.7"	"208.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TED0"	"U3 small nucleolar RNA-associated protein 15 homolog OS=Homo sapiens OX=9606 GN=UTP15 PE=1 SV=3"	"3"	"1"	"2"	"1"	"518"	"58.4"	"9.11"	"335.09"	"3.32"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"ER/Golgi;nucleus;other cell component"	""	"Pf00400, Pf09384"	"84135"	"ENSG00000164338"	"UTP15"	"B4DU75; B4DXK8; hsa:84135; Q6IA60; Q8TED0; Q96E08; Q9H9F8"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IYU8"	"Calcium uptake protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=MICU2 PE=1 SV=2"	"4"	"1"	"2"	"1"	"434"	"49.6"	"9.09"	"309.88"	"3.32"	"1"	"1"	"transport;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf13833"	"221154"	"ENSG00000165487"	"MICU2"	"hsa:221154; Q8IYU8; Q8N0T6; Q8NAX8"	""	"Processing of SMDT1"	"2"	"0"	"10.5"	"5.3"	"15.2"	"13.6"	"9.7"	"15.9"	"21.8"	"24.9"	"57.1"	"103.7"	"89.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95429"	"BAG family molecular chaperone regulator 4 OS=Homo sapiens OX=9606 GN=BAG4 PE=1 SV=1"	"2"	"1"	"2"	"1"	"457"	"49.6"	"5.12"	"329.71"	"3.32"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus"	"other molecular function"	"Pf02179"	"9530"	"ENSG00000156735"	"BAG4"	"B4E217; hsa:9530; O95429; O95818"	"Oxidative damage response"	"Signaling by FGFR1 in disease; Regulation of HSF1-mediated heat shock response; Signaling by plasma membrane FGFR1 fusions; TNF signaling"	"5"	"0"	"5.3"	"7.2"	"2.0"	"3.9"	"3.8"	"5.2"	"6.8"	"5.3"	"27.8"	"62.2"	"63.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9ULW3"	"Activator of basal transcription 1 OS=Homo sapiens OX=9606 GN=ABT1 PE=1 SV=1"	"7"	"1"	"2"	"1"	"272"	"31.1"	"9.88"	"395.25"	"3.32"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	""	"29777"	"ENSG00000146109"	"ABT1"	"hsa:29777; Q9ULW3"	""	""	"0"	"0"	"10.8"	"8.4"	"13.2"	"12.6"	"13.4"	"10.9"	"13.8"	"15.0"	"28.4"	"47.0"	"52.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P17096"	"High mobility group protein HMG-I/HMG-Y OS=Homo sapiens OX=9606 GN=HMGA1 PE=1 SV=3"	"25"	"2"	"4"	"2"	"107"	"11.7"	"10.32"	"1497.20"	"3.32"	"2"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	""	"3159"	"ENSG00000137309"	"HMGA1"	"hsa:3159; P10910; P17096; Q5T6U9; Q9UKB0"	"Adipogenesis; Pre-implantation embryo; Male infertility; 7q11.23 copy number variation syndrome; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Orexin receptor pathway"	"Vpr-mediated nuclear import of PICs; 2-LTR circle formation; Integration of viral DNA into host genomic DNA; Autointegration results in viral DNA circles; APOBEC3G mediated resistance to HIV-1 infection; Formation of Senescence-Associated Heterochromatin Foci (SAHF)"	"13"	"0"	"470.2"	"315.6"	"505.4"	"443.5"	"417.5"	"512.1"	"595.7"	"597.1"	"950.7"	"1460.1"	"1749.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95816"	"BAG family molecular chaperone regulator 2 OS=Homo sapiens OX=9606 GN=BAG2 PE=1 SV=1"	"5"	"1"	"2"	"1"	"211"	"23.8"	"6.70"	"304.34"	"3.31"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	""	"9532"	"ENSG00000112208"	"BAG2"	"B4DXE2; hsa:9532; O95816; Q08AS9; Q6FID0"	"Pleural mesothelioma"	"Regulation of HSF1-mediated heat shock response"	"2"	"0"	"4.9"	"6.6"	"6.3"	"4.9"	"8.3"	"7.7"	"6.5"	"9.9"	"14.1"	"33.0"	"28.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BPX5"	"Actin-related protein 2/3 complex subunit 5-like protein OS=Homo sapiens OX=9606 GN=ARPC5L PE=1 SV=1"	"8"	"1"	"2"	"1"	"153"	"16.9"	"6.60"	"424.26"	"3.31"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf04699"	"81873"	"ENSG00000136950"	"ARPC5L"	"hsa:81873; Q7Z523; Q9BPX5"	"Pathogenic Escherichia coli infection; VEGFA-VEGFR2 signaling"	""	"2"	"0"	"36.8"	"40.4"	"45.6"	"36.0"	"40.5"	"34.1"	"38.1"	"53.5"	"170.6"	"323.5"	"412.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TEQ6"	"Gem-associated protein 5 OS=Homo sapiens OX=9606 GN=GEMIN5 PE=1 SV=3"	"1"	"1"	"2"	"1"	"1508"	"168.5"	"6.62"	"259.81"	"3.31"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf00400, Pf12894"	"25929"	"ENSG00000082516"	"GEMIN5"	"hsa:25929; Q14CV0; Q8TEQ6; Q8WWV4; Q969W4; Q9H9K3; Q9UFI5"	""	"snRNP Assembly; SARS-CoV-2 modulates host translation machinery"	"2"	"0"	"6.4"	"6.0"	"3.6"	"4.9"	"8.2"	"6.9"	"5.3"	"9.0"	"21.1"	"59.9"	"96.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75347"	"Tubulin-specific chaperone A OS=Homo sapiens OX=9606 GN=TBCA PE=1 SV=3"	"10"	"1"	"2"	"1"	"108"	"12.8"	"5.29"	"493.82"	"3.30"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02970"	"6902"	"ENSG00000171530"	"TBCA"	"B4DT30; hsa:6902; O75347"	"VEGFA-VEGFR2 signaling"	"Post-chaperonin tubulin folding pathway"	"2"	"0"	"33.1"	"45.7"	"42.1"	"41.0"	"34.2"	"26.1"	"33.7"	"58.7"	"87.4"	"230.3"	"432.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7L2H7"	"Eukaryotic translation initiation factor 3 subunit M OS=Homo sapiens OX=9606 GN=EIF3M PE=1 SV=1"	"3"	"1"	"2"	"1"	"374"	"42.5"	"5.63"	"325.33"	"3.30"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01399, Pf18005"	"10480"	"ENSG00000149100"	"EIF3M"	"A8K7X4; B4E2Q4; hsa:10480; O60735; Q2F836; Q53HL6; Q7L2H7; Q9BXW1"	""	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition"	"6"	"0"	"21.4"	"22.8"	"26.1"	"16.0"	"26.7"	"20.7"	"27.1"	"36.8"	"72.0"	"130.7"	"429.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96DT7"	"Zinc finger and BTB domain-containing protein 10 OS=Homo sapiens OX=9606 GN=ZBTB10 PE=1 SV=2"	"2"	"1"	"2"	"1"	"871"	"94.8"	"5.16"	"408.21"	"3.29"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00651, Pf13909"	"65986"	"ENSG00000205189"	"ZBTB10"	"A4FVD0; hsa:65986; Q86W96; Q8IXI9; Q96DT7; Q96MH9"	""	""	"0"	"0"	"20.3"	"18.8"	"25.9"	"23.8"	"28.6"	"31.6"	"24.8"	"35.9"	"59.8"	"105.1"	"108.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EH3"	"Mitochondrial assembly of ribosomal large subunit protein 1 OS=Homo sapiens OX=9606 GN=MALSU1 PE=1 SV=1"	"5"	"1"	"2"	"1"	"234"	"26.2"	"5.49"	"415.57"	"3.29"	"1"	"1"	"other biological processes"	"cytosol;mitochondrion"	"translation activity"	"Pf02410"	"115416"	"ENSG00000156928"	"MALSU1"	"A4D154; hsa:115416; Q96EH3"	""	""	"0"	"0"	"3.3"	"3.4"	"6.9"	"5.3"	"4.7"	"3.8"	"7.2"	"17.6"	"66.9"	"157.0"	"270.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q06481"	"Amyloid-like protein 2 OS=Homo sapiens OX=9606 GN=APLP2 PE=1 SV=2"	"2"	"1"	"2"	"1"	"763"	"86.9"	"4.79"	"358.13"	"3.29"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00014, Pf02177, Pf10515, Pf12924, Pf12925"	"334"	"ENSG00000084234"	"APLP2"	"B3KXX9; H7BXI4; hsa:334; Q06481; Q13861; Q14594; Q14662; Q71U10; Q7M4L3; Q9BT36"	"Splicing factor NOVA regulated synaptic proteins"	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Platelet degranulation"	"4"	"0"	"0.0"	"4.9"	"4.3"	"2.5"	"3.9"	"3.8"	"7.3"	"9.8"	"12.7"	"29.1"	"35.6"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92556"	"Engulfment and cell motility protein 1 OS=Homo sapiens OX=9606 GN=ELMO1 PE=1 SV=2"	"2"	"2"	"3"	"2"	"727"	"83.8"	"6.28"	"586.46"	"3.28"	"2"	"1"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf04727, Pf11841, Pf16457"	"9844"	"ENSG00000155849"	"ELMO1"	"A4D1X6; hsa:9844; Q29R79; Q6ZTJ0; Q92556; Q96PB0; Q9H0I1"	"Chemokine signaling pathway; CCL18 signaling pathway"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; VEGFA-VEGFR2 Pathway; PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases; Nef and signal transduction"	"7"	"0"	"81.6"	"75.4"	"87.9"	"73.1"	"113.5"	"169.9"	"279.4"	"461.1"	"292.9"	"409.0"	"584.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51946"	"Cyclin-H OS=Homo sapiens OX=9606 GN=CCNH PE=1 SV=1"	"3"	"1"	"1"	"1"	"323"	"37.6"	"7.15"	""	"3.28"	""	"1"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"enzyme regulator activity"	"Pf00134, Pf16899"	"902"	"ENSG00000134480"	"CCNH"	"hsa:902; P51946; Q53X72; Q8TBL9"	"Cell cycle; Eukaryotic transcription initiation; G1 to S cell cycle control; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Formation of the Early Elongation Complex; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; Cyclin D associated events in G1; Cyclin A/B1/B2 associated events during G2/M transition; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Cyclin E associated events during G1/S transition ; Cyclin A:Cdk2-associated events at S phase entry"	"39"	"0"	"5.4"	"5.0"	"15.0"	"5.9"	"12.6"	"10.4"	"10.8"	"16.4"	"59.8"	"142.0"	"219.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86YP4"	"Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1"	"2"	"1"	"2"	"1"	"633"	"68.0"	"9.94"	"405.93"	"3.26"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00320, Pf16563"	"54815"	"ENSG00000167491"	"GATAD2A"	"B5MC40; hsa:54815; Q7L3J2; Q86YP4; Q96F28; Q9NPU2; Q9NXS1"	""	"RNA Polymerase I Transcription Initiation; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Potential therapeutics for SARS; Regulation of PTEN gene transcription; HDACs deacetylate histones; Regulation of TP53 Activity through Acetylation"	"6"	"0"	"81.0"	"81.3"	"77.4"	"64.6"	"80.7"	"74.3"	"88.8"	"110.4"	"117.8"	"261.2"	"413.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQS8"	"FYVE and coiled-coil domain-containing protein 1 OS=Homo sapiens OX=9606 GN=FYCO1 PE=1 SV=3"	"1"	"1"	"2"	"1"	"1478"	"166.9"	"4.92"	"417.89"	"3.26"	"1"	"1"	"transport;other biological processes"	"ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01363, Pf02759"	"79443"	"ENSG00000163820"	"FYCO1"	"B7ZKT7; hsa:79443; Q3MJE6; Q86T41; Q86TB1; Q8TEF9; Q96IV5; Q9BQS8; Q9H8P9"	"Clock-controlled autophagy in bone metabolism"	""	"1"	"0"	"18.2"	"10.6"	"25.0"	"21.6"	"19.0"	"21.1"	"24.3"	"31.5"	"51.1"	"94.9"	"141.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6DCA0"	"AMMECR1-like protein OS=Homo sapiens OX=9606 GN=AMMECR1L PE=1 SV=1"	"4"	"1"	"2"	"1"	"310"	"34.5"	"8.98"	"329.79"	"3.26"	"1"	"1"	""	""	""	"Pf01871"	"83607"	"ENSG00000144233"	"AMMECR1L"	"B4E276; hsa:83607; Q6DCA0"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9GZS1"	"DNA-directed RNA polymerase I subunit RPA49 OS=Homo sapiens OX=9606 GN=POLR1E PE=1 SV=3"	"3"	"1"	"2"	"1"	"419"	"47.2"	"8.94"	"340.79"	"3.25"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf06870"	"64425"	"ENSG00000137054"	"POLR1E"	"hsa:64425; Q5VZT3; Q8NBA9; Q96L20; Q9GZS1"	"Pyrimidine metabolism; Eukaryotic transcription initiation; 2q13 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"8"	"0"	"32.3"	"29.0"	"48.6"	"42.3"	"37.0"	"41.8"	"50.6"	"92.5"	"175.6"	"241.4"	"324.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00257"	"E3 SUMO-protein ligase CBX4 OS=Homo sapiens OX=9606 GN=CBX4 PE=1 SV=3"	"5"	"2"	"3"	"2"	"560"	"61.3"	"9.36"	"546.56"	"3.25"	"2"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00385, Pf17218"	"8535"	"ENSG00000141582"	"CBX4"	"B1PJR7; hsa:8535; O00257; Q6TPI8; Q96C04"	""	"SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Oxidative Stress Induced Senescence; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Regulation of PTEN gene transcription"	"8"	"0"	"57.0"	"72.9"	"72.1"	"62.8"	"73.5"	"76.8"	"86.0"	"107.9"	"204.8"	"318.2"	"400.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y333"	"U6 snRNA-associated Sm-like protein LSm2 OS=Homo sapiens OX=9606 GN=LSM2 PE=1 SV=1"	"8"	"1"	"2"	"1"	"95"	"10.8"	"6.52"	"337.00"	"3.25"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01423"	"57819"	"ENSG00000172850; ENSG00000204392; ENSG00000224979; ENSG00000225998; ENSG00000231502; ENSG00000236826"	"LSM2"	"hsa:57819; Q6FGG1; Q9Y333"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA decay by 5' to 3' exoribonuclease"	"3"	"0"	"130.7"	"134.3"	"103.1"	"125.7"	"147.8"	"140.8"	"149.3"	"206.7"	"251.8"	"479.3"	"1101.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BU02"	"Thiamine-triphosphatase OS=Homo sapiens OX=9606 GN=THTPA PE=1 SV=3"	"6"	"1"	"1"	"1"	"230"	"25.6"	"4.82"	""	"3.25"	""	"1"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf01928"	"79178"	"ENSG00000259431"	"THTPA"	"D3DS50; G3V4J3; hsa:79178; Q9BU02"	""	"Vitamin B1 (thiamin) metabolism"	"1"	"0"	"46.3"	"41.3"	"43.5"	"37.0"	"45.7"	"53.8"	"50.2"	"71.5"	"78.3"	"129.3"	"178.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BRG1"	"Vacuolar protein-sorting-associated protein 25 OS=Homo sapiens OX=9606 GN=VPS25 PE=1 SV=1"	"17"	"3"	"4"	"3"	"176"	"20.7"	"6.34"	"1870.18"	"3.23"	"3"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf05871"	"84313"	"ENSG00000131475"	"VPS25"	"B2R581; hsa:84313; Q9BRG1"	""	"HCMV Late Events; Endosomal Sorting Complex Required For Transport (ESCRT)"	"2"	"0"	"50.7"	"50.8"	"67.2"	"58.2"	"99.3"	"129.4"	"191.0"	"335.9"	"530.5"	"701.0"	"758.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75529"	"TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L OS=Homo sapiens OX=9606 GN=TAF5L PE=1 SV=1"	"2"	"1"	"2"	"1"	"589"	"66.1"	"5.88"	"464.85"	"3.22"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00400, Pf04494"	"27097"	"ENSG00000135801"	"TAF5L"	"hsa:27097; O75529; Q5TDI5; Q5TDI6; Q8IW31"	""	"HATs acetylate histones"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BTD8"	"RNA-binding protein 42 OS=Homo sapiens OX=9606 GN=RBM42 PE=1 SV=1"	"2"	"1"	"2"	"1"	"480"	"50.4"	"9.63"	"368.80"	"3.22"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"79171"	"ENSG00000126254"	"RBM42"	"hsa:79171; O00320; Q8N5R7; Q9BTD8; Q9BU66"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"25.7"	"29.3"	"23.6"	"15.7"	"18.5"	"16.5"	"24.7"	"41.6"	"75.2"	"130.0"	"195.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P54289"	"Voltage-dependent calcium channel subunit alpha-2/delta-1 OS=Homo sapiens OX=9606 GN=CACNA2D1 PE=1 SV=3"	"1"	"1"	"2"	"1"	"1103"	"124.5"	"5.27"	"317.92"	"3.22"	"1"	"1"	"cell-cell signaling;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"transporter activity;other molecular function"	"Pf08399, Pf08473, Pf13768"	"781"	"ENSG00000153956"	"CACNA2D1"	"hsa:781; P54289; Q17R45; Q9UD80; Q9UD81; Q9UD82"	"Arrhythmogenic right ventricular cardiomyopathy; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Disturbed pathways in Duchenne Muscular Dystrophy"	""	"4"	"0"	"8.4"	"8.5"	"8.8"	"7.6"	"11.6"	"7.4"	"15.4"	"16.4"	"33.2"	"71.4"	"121.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13056"	"Nuclear receptor subfamily 2 group C member 1 OS=Homo sapiens OX=9606 GN=NR2C1 PE=1 SV=2"	"4"	"1"	"1"	"1"	"603"	"67.3"	"6.32"	""	"3.22"	""	"1"	"signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00104, Pf00105"	"7181"	"ENSG00000120798"	"NR2C1"	"A8K5K4; hsa:7181; P13056; Q15625; Q15626"	""	"Nuclear Receptor transcription pathway; SUMOylation of intracellular receptors"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H2G2"	"STE20-like serine/threonine-protein kinase OS=Homo sapiens OX=9606 GN=SLK PE=1 SV=1"	"2"	"1"	"1"	"1"	"1235"	"142.6"	"5.15"	""	"3.22"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf12474"	"9748"	"ENSG00000065613"	"SLK"	"D3DRA0; D3DRA1; hsa:9748; O00211; Q6P1Z4; Q86WU7; Q86WW1; Q92603; Q9H2G2; Q9NQL0; Q9NQL1"	"TAR syndrome"	"RHOA GTPase cycle; RHOC GTPase cycle; RHOB GTPase cycle"	"4"	"0"	"3.4"	"4.4"	"2.4"	"6.4"	"5.9"	"5.2"	"6.5"	"6.2"	"10.8"	"32.7"	"61.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P1X6"	"UPF0598 protein C8orf82 OS=Homo sapiens OX=9606 GN=C8orf82 PE=1 SV=2"	"5"	"1"	"2"	"1"	"216"	"23.9"	"9.14"	"322.13"	"3.22"	"1"	"1"	""	""	""	"Pf14956"	"414919"	"ENSG00000213563"	"C8orf82"	"hsa:414919; Q6GMR2; Q6P1X6; Q6P2Q7"	""	""	"0"	"0"	"8.7"	"6.7"	"10.5"	"12.2"	"9.1"	"10.5"	"9.6"	"30.8"	"80.9"	"181.3"	"297.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BVG4"	"Protein PBDC1 OS=Homo sapiens OX=9606 GN=PBDC1 PE=1 SV=1"	"5"	"1"	"2"	"1"	"233"	"26.0"	"4.79"	"364.96"	"3.21"	"1"	"1"	""	""	""	"Pf04669"	"51260"	"ENSG00000102390"	"PBDC1"	"hsa:51260; Q9BVG4"	""	""	"0"	"0"	"18.4"	"14.9"	"18.3"	"13.8"	"13.0"	"17.8"	"23.7"	"23.9"	"77.5"	"143.6"	"190.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NUG6"	"p53 and DNA damage-regulated protein 1 OS=Homo sapiens OX=9606 GN=PDRG1 PE=1 SV=2"	"10"	"1"	"2"	"1"	"133"	"15.5"	"6.06"	"342.70"	"3.21"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other cell component"	"other molecular function"	"Pf01920"	"81572"	"ENSG00000088356"	"PDRG1"	"B2R511; hsa:81572; Q96GP3; Q9BUW8; Q9NUG6"	""	""	"0"	"0"	"26.2"	"17.2"	"28.0"	"21.4"	"25.3"	"29.1"	"36.8"	"40.3"	"159.8"	"345.8"	"538.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61026"	"Ras-related protein Rab-10 OS=Homo sapiens OX=9606 GN=RAB10 PE=1 SV=1"	"6"	"1"	"2"	"1"	"200"	"22.5"	"8.38"	"439.37"	"3.21"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00071"	"10890"	"ENSG00000084733"	"RAB10"	"D6W538; hsa:10890; O88386; P61026; Q6IA52; Q9D7X6; Q9H0T3"	"Focal adhesion: PI3K-Akt-mTOR-signaling pathway"	"RAB GEFs exchange GTP for GDP on RABs; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Neutrophil degranulation; RAB geranylgeranylation"	"5"	"0"	"11.4"	"12.1"	"11.5"	"12.1"	"12.6"	"9.4"	"14.4"	"12.2"	"36.7"	"76.5"	"114.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TC92"	"Ecto-NOX disulfide-thiol exchanger 1 OS=Homo sapiens OX=9606 GN=ENOX1 PE=1 SV=1"	"2"	"1"	"2"	"1"	"643"	"73.3"	"5.54"	"288.19"	"3.20"	"1"	"1"	"other biological processes"	"non-structural extracellular;plasma membrane;other membranes"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"55068"	"ENSG00000120658"	"ENOX1"	"A4GU15; A6NMH9; B7Z5K1; hsa:55068; Q2TU81; Q5VT11; Q8TC92; Q9NWE0"	""	""	"0"	"0"	"6.6"	"5.2"	"5.7"	"5.6"	"4.9"	"5.8"	"7.6"	"8.5"	"17.3"	"38.0"	"44.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86Y07"	"Serine/threonine-protein kinase VRK2 OS=Homo sapiens OX=9606 GN=VRK2 PE=1 SV=3"	"2"	"1"	"2"	"1"	"508"	"58.1"	"8.84"	"418.53"	"3.20"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"other membranes;mitochondrion;ER/Golgi;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"7444"	"ENSG00000028116"	"VRK2"	"B4DKL0; D6W5D4; D6W5D6; hsa:7444; Q49AK9; Q53EU9; Q53S39; Q53S77; Q53TU1; Q86Y07; Q86Y08; Q86Y09; Q86Y10; Q86Y11; Q86Y12; Q8IXI5; Q99987"	""	"RAC1 GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOD GTPase cycle"	"5"	"0"	"23.5"	"23.6"	"31.7"	"21.9"	"27.6"	"32.2"	"30.7"	"40.0"	"62.3"	"108.1"	"126.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75487"	"Glypican-4 OS=Homo sapiens OX=9606 GN=GPC4 PE=1 SV=4"	"3"	"2"	"3"	"2"	"556"	"62.4"	"6.68"	"608.61"	"3.20"	"2"	"1"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;signal transduction;other biological processes"	"extracellular matrix;plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf01153"	"2239"	"ENSG00000076716"	"GPC4"	"B2R6J7; B4E2C0; hsa:2239; O75487; Q6ZMA6; Q96L43; Q9NU08; Q9UJN1; Q9UPD9"	"Wnt signaling"	"A tetrasaccharide linker sequence is required for GAG synthesis; HS-GAG biosynthesis; HS-GAG degradation; Defective B4GALT7 causes EDS, progeroid type; Defective B3GAT3 causes JDSSDHD; Defective EXT2 causes exostoses 2; Defective EXT1 causes exostoses 1, TRPS2 and CHDS; Defective B3GALT6 causes EDSP2 and SEMDJL1; Attachment and Entry; Retinoid metabolism and transport"	"11"	"0"	"214.8"	"220.7"	"195.7"	"164.1"	"234.3"	"220.2"	"237.2"	"292.2"	"396.0"	"724.0"	"1133.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25105"	"Platelet-activating factor receptor OS=Homo sapiens OX=9606 GN=PTAFR PE=1 SV=1"	"5"	"1"	"1"	"1"	"342"	"39.2"	"8.95"	""	"3.19"	""	"1"	"other metabolic processes;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes"	"other molecular function"	"Pf00001"	"5724"	"ENSG00000169403"	"PTAFR"	"A3KMC8; A8K2H5; hsa:5724; P25105"	"Small ligand GPCRs; GPCRs, class A rhodopsin-like"	"Neutrophil degranulation; G alpha (q) signalling events; Interleukin-10 signaling; Interferon gamma signaling; Class A/1 (Rhodopsin-like receptors)"	"7"	"0"	"146.5"	"111.0"	"180.7"	"142.8"	"182.1"	"162.5"	"196.5"	"231.8"	"247.1"	"331.3"	"454.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P41208"	"Centrin-2 OS=Homo sapiens OX=9606 GN=CETN2 PE=1 SV=1"	"8"	"1"	"2"	"1"	"172"	"19.7"	"5.00"	"265.25"	"3.19"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;transport;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf13499"	"1069"	"ENSG00000147400"	"CETN2"	"B2R4T4; hsa:1069; P41208; Q53XW1"	"Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; SUMOylation of DNA damage response and repair proteins; Formation of Incision Complex in GG-NER; DNA Damage Recognition in GG-NER"	"13"	"0"	"35.6"	"27.3"	"42.2"	"39.5"	"43.0"	"47.3"	"75.0"	"193.1"	"475.0"	"949.5"	"1347.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A6NCE7"	"Microtubule-associated proteins 1A/1B light chain 3 beta 2 OS=Homo sapiens OX=9606 GN=MAP1LC3B2 PE=2 SV=1"	"8"	"1"	"1"	"1"	"125"	"14.6"	"8.68"	""	"3.19"	""	"1"	"cell organization and biogenesis;other metabolic processes;stress response"	"other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02991"	"643246"	"ENSG00000258102"	"MAP1LC3B2"	"A6NCE7; hsa:643246"	""	""	"0"	"0"	"65.3"	"43.4"	"72.9"	"66.8"	"75.4"	"75.6"	"67.3"	"80.4"	"180.9"	"349.1"	"484.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4W2"	"Ribosomal biogenesis protein LAS1L OS=Homo sapiens OX=9606 GN=LAS1L PE=1 SV=2"	"3"	"2"	"3"	"2"	"734"	"83.0"	"4.73"	"779.56"	"3.19"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf04031"	"81887"	"ENSG00000001497"	"LAS1L"	"A9X410; hsa:81887; Q5JXQ0; Q8TEN5; Q9H9V5; Q9Y4W2"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"98.1"	"85.6"	"114.4"	"93.7"	"113.6"	"89.3"	"120.7"	"163.7"	"221.1"	"373.2"	"572.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NVS2"	"39S ribosomal protein S18a, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS18A PE=1 SV=1"	"8"	"1"	"1"	"1"	"196"	"22.2"	"10.33"	""	"3.19"	""	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf01084"	"55168"	"ENSG00000096080"	"MRPS18A"	"A6XND3; hsa:55168; Q5QPA4; Q9NVS2"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6PJG2"	"Mitotic deacetylase-associated SANT domain protein OS=Homo sapiens OX=9606 GN=MIDEAS PE=1 SV=2"	"1"	"1"	"2"	"1"	"1045"	"114.9"	"9.19"	"268.17"	"3.18"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01448"	"91748"	"ENSG00000156030"	"MIDEAS"	"hsa:91748; Q6PJG2; Q6PK13; Q6PK59; Q6ZS23"	""	""	"0"	"0"	"30.5"	"26.5"	"28.8"	"31.9"	"25.1"	"24.3"	"32.1"	"38.5"	"74.5"	"142.3"	"188.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UL25"	"Ras-related protein Rab-21 OS=Homo sapiens OX=9606 GN=RAB21 PE=1 SV=3"	"5"	"1"	"2"	"1"	"225"	"24.3"	"7.94"	"325.16"	"3.18"	"1"	"1"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00071"	"23011"	"ENSG00000080371"	"RAB21"	"hsa:23011; Q14466; Q569H3; Q9UL25"	"Ciliary landscape"	"RAB GEFs exchange GTP for GDP on RABs; RAB geranylgeranylation"	"3"	"0"	"22.6"	"21.5"	"24.4"	"21.7"	"25.4"	"10.3"	"20.6"	"33.4"	"60.1"	"100.8"	"182.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15052"	"Rho guanine nucleotide exchange factor 6 OS=Homo sapiens OX=9606 GN=ARHGEF6 PE=1 SV=2"	"1"	"1"	"2"	"1"	"776"	"87.4"	"6.05"	"270.49"	"3.18"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;signal transduction;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity"	"Pf00169, Pf00307, Pf00621, Pf07653, Pf16523, Pf16614, Pf16615"	"9459"	"ENSG00000129675"	"ARHGEF6"	"A6NMW9; A8K6S7; B1AL37; hsa:9459; Q15052; Q15396; Q5JQ66; Q7Z3W1; Q86XH0"	"Pancreatic adenocarcinoma pathway; Regulation of actin cytoskeleton"	"CDC42 GTPase cycle; RAC1 GTPase cycle; RHOU GTPase cycle; NRAGE signals death through JNK; G alpha (12/13) signalling events; G beta:gamma signalling through CDC42; Regulation of cytoskeletal remodeling and cell spreading by IPP complex components"	"9"	"0"	"21.7"	"20.5"	"19.1"	"13.6"	"22.2"	"16.5"	"24.8"	"25.3"	"74.8"	"134.5"	"174.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51572"	"B-cell receptor-associated protein 31 OS=Homo sapiens OX=9606 GN=BCAP31 PE=1 SV=3"	"4"	"1"	"2"	"1"	"246"	"28.0"	"8.44"	"325.85"	"3.18"	"1"	"1"	"cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf05529, Pf18035"	"10134"	"ENSG00000185825"	"BCAP31"	"B3KQ79; D3DWV5; hsa:10134; P51572; Q13836; Q96CF0"	""	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC; RHOA GTPase cycle; Apoptotic cleavage of cellular proteins"	"4"	"0"	"43.4"	"33.2"	"42.0"	"47.6"	"57.3"	"57.6"	"65.7"	"71.4"	"115.6"	"232.7"	"326.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q93008"	"Probable ubiquitin carboxyl-terminal hydrolase FAF-X OS=Homo sapiens OX=9606 GN=USP9X PE=1 SV=3"	"1"	"2"	"3"	"2"	"2570"	"292.1"	"5.80"	"868.48"	"3.17"	"2"	"1"	"protein metabolism;other metabolic processes"	""	"other molecular function"	"Pf00443, Pf12030"	"100971796; 465582"	"ENSPPAG00000039671; ENSPTRG00000045541"	"USP9X"	"A0A2I3RAB4; A0A2J8JDU7; A0A2R9BVD0; A0A6D2WW26"	""	""	"0"	"0"	"71.1"	"69.8"	"96.3"	"71.6"	"83.7"	"73.3"	"114.2"	"165.3"	"296.1"	"499.7"	"753.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H981"	"Actin-related protein 8 OS=Homo sapiens OX=9606 GN=ACTR8 PE=1 SV=2"	"2"	"1"	"2"	"1"	"624"	"70.4"	"7.78"	"611.78"	"3.17"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus"	"other molecular function"	"Pf00022"	"93973"	"ENSG00000113812"	"ACTR8"	"B3KSW7; hsa:93973; Q8N566; Q9H663; Q9H981"	""	"UCH proteinases; DNA Damage Recognition in GG-NER"	"2"	"0"	"8.6"	"8.3"	"4.3"	"6.8"	"7.3"	"9.1"	"10.6"	"12.9"	"43.1"	"111.3"	"148.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9C0H9"	"SRC kinase signaling inhibitor 1 OS=Homo sapiens OX=9606 GN=SRCIN1 PE=1 SV=4"	"1"	"1"	"2"	"1"	"1183"	"127.0"	"9.38"	"294.70"	"3.17"	"1"	"1"	"cell adhesion;cell organization and biogenesis;transport;other biological processes"	"cytoskeleton;other cell component"	"other molecular function"	"Pf03915"	"80725"	"ENSG00000273608; ENSG00000277363"	"SRCIN1"	"hsa:80725; Q75T46; Q8N4W8; Q9C0H9"	"17q12 copy number variation syndrome"	""	"1"	"0"	"18.0"	"15.5"	"21.1"	"20.3"	"20.6"	"18.1"	"31.9"	"28.4"	"43.6"	"93.2"	"128.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12923"	"Tyrosine-protein phosphatase non-receptor type 13 OS=Homo sapiens OX=9606 GN=PTPN13 PE=1 SV=2"	"1"	"1"	"2"	"1"	"2485"	"276.7"	"6.42"	"405.90"	"3.17"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00102, Pf00373, Pf00595, Pf09379, Pf09380, Pf16599"	"5783"	"ENSG00000163629"	"PTPN13"	"B2RTR0; hsa:5783; Q12923; Q15159; Q15263; Q15264; Q15265; Q15674; Q16826; Q8IWH7; Q9NYN9; Q9UDA8"	"Apoptosis modulation and signaling; Ectoderm differentiation; Ectoderm differentiation"	"Synthesis of PIPs at the plasma membrane; RND2 GTPase cycle; RND3 GTPase cycle; RND1 GTPase cycle; Interleukin-37 signaling"	"8"	"0"	"5.7"	"5.9"	"2.1"	"6.8"	"6.4"	"5.1"	"10.4"	"10.1"	"14.3"	"26.0"	"34.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75554"	"WW domain-binding protein 4 OS=Homo sapiens OX=9606 GN=WBP4 PE=1 SV=1"	"3"	"1"	"2"	"1"	"376"	"42.5"	"5.57"	"420.61"	"3.17"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00397, Pf06220"	"11193"	"ENSG00000120688"	"WBP4"	"B7Z4M2; hsa:11193; O75554; Q32P29"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"29.9"	"26.4"	"27.4"	"26.4"	"26.4"	"23.5"	"29.4"	"30.1"	"38.5"	"68.8"	"120.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N0X4"	"Citramalyl-CoA lyase, mitochondrial OS=Homo sapiens OX=9606 GN=CLYBL PE=1 SV=2"	"3"	"1"	"2"	"1"	"340"	"37.3"	"8.73"	"343.21"	"3.16"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"mitochondrion"	"other molecular function"	"Pf03328"	"171425"	"ENSG00000125246"	"CLYBL"	"hsa:171425; Q5W0F7; Q8N0X4; Q8TDH8"	""	""	"0"	"0"	"2.0"	"3.6"	"5.1"	"3.3"	"5.0"	"8.5"	"24.6"	"71.4"	"200.9"	"285.4"	"483.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55060"	"Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3"	"1"	"1"	"1"	"1"	"971"	"110.3"	"5.77"	""	"3.16"	""	"1"	"transport"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf03378, Pf03810, Pf08506"	"1434"	"ENSG00000124207"	"CSE1L"	"A3RLL6; B2R5T4; E1P5Y0; F8W904; hsa:1434; O75432; P55060; Q32M40; Q9H5B7; Q9NTS0; Q9UP98; Q9UP99; Q9UPA0"	""	""	"0"	"0"	"16.2"	"17.5"	"23.4"	"22.7"	"22.8"	"18.3"	"23.7"	"44.1"	"65.8"	"220.6"	"320.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3D3"	"28S ribosomal protein S16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS16 PE=1 SV=1"	"9"	"1"	"1"	"1"	"137"	"15.3"	"9.50"	""	"3.14"	""	"1"	"protein metabolism;other metabolic processes"	"other membranes;cytosol;mitochondrion;translational apparatus"	"other molecular function"	"Pf00886"	"51021"	"ENSG00000182180"	"MRPS16"	"B4E032; hsa:51021; Q96Q60; Q9Y3D3"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"15.4"	"12.1"	"16.7"	"17.1"	"18.4"	"19.6"	"23.6"	"24.8"	"26.2"	"44.1"	"59.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EY5"	"Multivesicular body subunit 12A OS=Homo sapiens OX=9606 GN=MVB12A PE=1 SV=1"	"4"	"1"	"2"	"1"	"273"	"28.8"	"8.91"	"295.74"	"3.14"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf10240"	"93343"	"ENSG00000141971"	"MVB12A"	"hsa:93343; Q96EY5; Q96I18"	"7q11.23 copy number variation syndrome"	"Budding and maturation of HIV virion; Membrane binding and targetting of GAG proteins; Endosomal Sorting Complex Required For Transport (ESCRT); Late endosomal microautophagy; HCMV Late Events"	"6"	"0"	"31.7"	"30.0"	"30.4"	"35.2"	"38.2"	"34.2"	"42.7"	"77.6"	"232.2"	"320.0"	"380.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60866"	"40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1"	"9"	"1"	"2"	"1"	"119"	"13.4"	"9.94"	"361.29"	"3.14"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00338"	"6224"	"ENSG00000008988"	"RPS20"	"B2R4F4; B4DW28; hsa:6224; P17075; P60866; Q5M8S9"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"59.7"	"57.3"	"62.3"	"65.7"	"77.1"	"72.5"	"75.5"	"86.6"	"127.3"	"188.1"	"257.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92947"	"Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1"	"3"	"1"	"2"	"1"	"438"	"48.1"	"8.06"	"354.70"	"3.14"	"1"	"1"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00441, Pf02770, Pf02771"	"2639"	"ENSG00000105607"	"GCDH"	"A8K2Z2; hsa:2639; O14719; Q92947"	"Fatty acid beta-oxidation; Tryptophan metabolism"	"Lysine catabolism"	"3"	"0"	"9.4"	"7.5"	"7.8"	"6.2"	"8.4"	"5.3"	"11.9"	"13.8"	"18.9"	"39.6"	"54.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62877"	"E3 ubiquitin-protein ligase RBX1 OS=Homo sapiens OX=9606 GN=RBX1 PE=1 SV=1"	"13"	"1"	"2"	"1"	"108"	"12.3"	"6.96"	"275.67"	"3.14"	"1"	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf12678"	"9978"	"ENSG00000100387"	"RBX1"	"B2RDY1; hsa:9978; P62877; Q8N6Z8; Q9D1S2; Q9WUK9; Q9Y254"	"Cell cycle; Dual hijack model of Vif in HIV infection; Type 2 papillary renal cell carcinoma; NRF2-ARE regulation; Hippo-Merlin signaling dysregulation; 22q11.2 copy number variation syndrome; Nucleotide excision repair; Hijack of ubiquitination by SARS-CoV-2; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; 1p36 copy number variation syndrome"	"Potential therapeutics for SARS; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; Dual Incision in GG-NER; Regulation of expression of SLITs and ROBOs; Antigen processing: Ubiquitination & Proteasome degradation; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Degradation of DVL; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; Orc1 removal from chromatin; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Neddylation; Interleukin-1 signaling; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Regulation of BACH1 activity; NOTCH1 Intracellular Domain Regulates Transcription; Formation of TC-NER Pre-Incision Complex; Prolactin receptor signaling; DNA Damage Recognition in GG-NER; Nuclear events stimulated by ALK signaling in cancer; Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling"	"46"	"0"	"34.1"	"38.7"	"40.2"	"37.5"	"38.9"	"34.9"	"44.0"	"76.3"	"163.2"	"338.1"	"446.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NWB1"	"RNA binding protein fox-1 homolog 1 OS=Homo sapiens OX=9606 GN=RBFOX1 PE=1 SV=2"	"3"	"1"	"2"	"1"	"397"	"42.8"	"6.86"	"422.36"	"3.13"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf12414"	"54715"	"ENSG00000078328"	"RBFOX1"	"hsa:54715; Q7Z7I7; Q8TAE3; Q8TAF2; Q8WYB2; Q9NS20; Q9NWB1"	"MECP2 and associated Rett syndrome"	"MECP2 regulates transcription factors"	"2"	"0"	"63.7"	"61.1"	"82.8"	"66.8"	"68.3"	"73.6"	"98.5"	"129.1"	"217.0"	"360.3"	"496.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4X0"	"AMME syndrome candidate gene 1 protein OS=Homo sapiens OX=9606 GN=AMMECR1 PE=1 SV=1"	"4"	"1"	"2"	"1"	"333"	"35.4"	"8.63"	"305.14"	"3.13"	"1"	"1"	""	"mitochondrion;nucleus"	""	"Pf01871"	"9949"	"ENSG00000101935"	"AMMECR1"	"hsa:9949; Q5JYV9; Q6P9D8; Q8WX22; Q9UIQ8; Q9Y4X0"	""	""	"0"	"0"	"13.9"	"10.5"	"14.7"	"15.7"	"16.2"	"12.5"	"18.3"	"17.6"	"39.3"	"83.0"	"103.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8ND76"	"Cyclin-Y OS=Homo sapiens OX=9606 GN=CCNY PE=1 SV=2"	"4"	"1"	"2"	"1"	"341"	"39.3"	"7.20"	"325.54"	"3.13"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;signal transduction;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00134"	"219771"	"ENSG00000108100"	"CCNY"	"B7ZKX9; D3DRY9; hsa:219771; Q2M3V4; Q2TU96; Q6NT86; Q7Z4U7; Q8ND76; Q8TEX2; Q8TEX3; Q96M99; Q96P45"	""	""	"0"	"0"	"2.3"	"9.0"	"9.5"	"9.9"	"7.6"	"7.6"	"8.9"	"12.9"	"31.5"	"97.4"	"130.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00303"	"Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1"	"3"	"1"	"1"	"1"	"357"	"37.5"	"5.45"	""	"3.13"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01398, Pf13012"	"8665"	"ENSG00000175390"	"EIF3F"	"A8K0S2; hsa:8665; O00303; Q6IB45; Q8N978"	"Translation factors; VEGFA-VEGFR2 signaling; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"9"	"0"	"12.9"	"14.0"	"18.0"	"13.1"	"13.0"	"14.3"	"20.0"	"35.4"	"52.0"	"86.7"	"384.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94782"	"Ubiquitin carboxyl-terminal hydrolase 1 OS=Homo sapiens OX=9606 GN=USP1 PE=1 SV=1"	"3"	"1"	"1"	"1"	"785"	"88.2"	"5.45"	""	"3.13"	""	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00443"	"7398"	"ENSG00000162607"	"USP1"	"A0PJ95; D3DQ57; hsa:7398; O94782; Q05BX7; Q59H66; Q9UFR0; Q9UNJ3"	"miR-517 relationship with ARCN1 and USP1; DNA repair pathways, full network"	"Fanconi Anemia Pathway; Recognition of DNA damage by PCNA-containing replication complex"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3L5"	"Ras-related protein Rap-2c OS=Homo sapiens OX=9606 GN=RAP2C PE=1 SV=1"	"7"	"1"	"2"	"1"	"183"	"20.7"	"4.94"	"429.29"	"3.12"	"1"	"1"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00071"	"57826"	"ENSG00000123728"	"RAP2C"	"B3KWD6; hsa:57826; Q5H9H9; Q9BTS0; Q9Y3L5"	""	"Neutrophil degranulation"	"1"	"0"	"39.7"	"45.1"	"50.7"	"56.5"	"49.7"	"42.8"	"59.6"	"82.6"	"161.8"	"299.4"	"401.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60613"	"Selenoprotein F OS=Homo sapiens OX=9606 GN=SELENOF PE=1 SV=4"	"8"	"1"	"2"	"1"	"165"	"18.1"	"5.03"	"264.28"	"3.12"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"ER/Golgi"	"other molecular function"	"Pf08806"	"9403"	"ENSG00000183291"	"SELENOF"	"A0A0B4J1S4; hsa:9403; O60613; Q4GZG7; Q8WU00; Q9BS64; Q9GZW0; Q9NR01"	"Selenium metabolism / selenoproteins; Selenium micronutrient network"	""	"2"	"0"	"29.3"	"29.8"	"37.0"	"34.1"	"33.7"	"44.7"	"41.5"	"54.8"	"131.3"	"219.5"	"282.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46934"	"E3 ubiquitin-protein ligase NEDD4 OS=Homo sapiens OX=9606 GN=NEDD4 PE=1 SV=4"	"1"	"1"	"2"	"1"	"1319"	"149.0"	"6.58"	"411.64"	"3.12"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00397, Pf00632"	"4734"	"ENSG00000069869"	"NEDD4"	"A1KY35; A6ND72; A7MD29; B4E2R7; B7ZM59; B7ZM60; B9EGN5; D6RF89; hsa:4734; P46934"	"Proteasome degradation; Ebola virus infection in host; EGF/EGFR signaling pathway; LDLRAD4 and what we know about it"	"Antigen processing: Ubiquitination & Proteasome degradation; Regulation of PTEN stability and activity; ISG15 antiviral mechanism; Downregulation of ERBB4 signaling; Regulation of PTEN localization"	"9"	"0"	"9.4"	"7.5"	"17.7"	"9.5"	"10.6"	"9.1"	"15.1"	"17.5"	"43.4"	"225.3"	"379.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4X5"	"E3 ubiquitin-protein ligase ARIH1 OS=Homo sapiens OX=9606 GN=ARIH1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"557"	"64.1"	"5.08"	"292.56"	"3.11"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01485, Pf19422"	"25820"	"ENSG00000166233"	"ARIH1"	"B2R6U3; hsa:25820; O76026; Q9H3T6; Q9UEN0; Q9UP39; Q9Y4X5"	""	"ISG15 antiviral mechanism"	"1"	"0"	"16.3"	"9.9"	"15.0"	"14.9"	"15.3"	"16.7"	"21.1"	"27.9"	"61.4"	"87.9"	"109.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TBB5"	"Kelch domain-containing protein 4 OS=Homo sapiens OX=9606 GN=KLHDC4 PE=1 SV=1"	"2"	"1"	"2"	"1"	"520"	"57.9"	"5.72"	"331.37"	"3.11"	"1"	"1"	""	""	""	"Pf07646, Pf13418, Pf13854, Pf13964"	"54758"	"ENSG00000104731"	"KLHDC4"	"D3DUN3; D3DUN4; D3DUN5; hsa:54758; Q8TBB5; Q96F29; Q9BVN3"	""	""	"0"	"0"	"3.9"	"0.0"	"6.0"	"2.3"	"3.4"	"1.8"	"9.0"	"5.5"	"40.9"	"81.6"	"72.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00154"	"Cytosolic acyl coenzyme A thioester hydrolase OS=Homo sapiens OX=9606 GN=ACOT7 PE=1 SV=3"	"3"	"1"	"1"	"1"	"380"	"41.8"	"8.54"	""	"3.11"	""	"1"	"other metabolic processes"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf03061"	"11332"	"ENSG00000097021"	"ACOT7"	"A8K0K7; A8K232; A8K6B8; A8K837; B3KQ12; hsa:11332; O00154; O43703; Q53Y78; Q5JYL2; Q5JYL3; Q5JYL4; Q5JYL5; Q5JYL6; Q5TGR4; Q9UJM9; Q9Y539; Q9Y540"	""	"Mitochondrial Fatty Acid Beta-Oxidation"	"1"	"0"	"8.5"	"13.3"	"9.0"	"8.3"	"14.0"	"4.9"	"11.6"	"18.3"	"42.7"	"178.3"	"667.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46199"	"Translation initiation factor IF-2, mitochondrial OS=Homo sapiens OX=9606 GN=MTIF2 PE=1 SV=2"	"2"	"1"	"1"	"1"	"727"	"81.3"	"7.15"	""	"3.10"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00009, Pf11987"	"4528"	"ENSG00000085760"	"MTIF2"	"D6W5D0; hsa:4528; P46199"	""	"Mitochondrial translation initiation"	"1"	"0"	"20.8"	"9.2"	"47.0"	"43.8"	"27.2"	"27.0"	"28.1"	"21.4"	"66.5"	"113.0"	"139.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5T1M5"	"FK506-binding protein 15 OS=Homo sapiens OX=9606 GN=FKBP15 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1219"	"133.5"	"5.20"	"252.38"	"3.10"	"1"	"1"	"transport"	"other membranes;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00254"	"23307"	"ENSG00000119321"	"FKBP15"	"hsa:23307; Q05DK8; Q5T1M2; Q5T1M5; Q6DD85; Q9Y4D0"	"TYROBP causal network in microglia"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P84090"	"Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1"	"11"	"1"	"2"	"1"	"104"	"12.3"	"5.92"	"248.97"	"3.10"	"1"	"1"	"cell cycle OR cell proliferation;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf01133"	"2079"	"ENSG00000100632"	"ERH"	"B2R5H2; hsa:2079; P70659; P84090; Q14259"	""	""	"0"	"0"	"23.3"	"39.8"	"25.3"	"22.5"	"25.4"	"22.3"	"37.3"	"48.2"	"87.8"	"257.6"	"438.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q02978"	"Mitochondrial 2-oxoglutarate/malate carrier protein OS=Homo sapiens OX=9606 GN=SLC25A11 PE=1 SV=3"	"4"	"1"	"2"	"1"	"314"	"34.0"	"9.91"	"386.90"	"3.10"	"1"	"1"	"other metabolic processes;transport"	"plasma membrane;other membranes;mitochondrion"	"transporter activity"	"Pf00153"	"8402"	"ENSG00000108528"	"SLC25A11"	"F5GY65; hsa:8402; O75537; Q02978; Q969P7"	"VEGFA-VEGFR2 signaling"	"Gluconeogenesis"	"2"	"0"	"4.1"	"5.9"	"0.0"	"6.7"	"4.6"	"4.4"	"2.7"	"6.6"	"27.0"	"68.7"	"94.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5T5C0"	"Syntaxin-binding protein 5 OS=Homo sapiens OX=9606 GN=STXBP5 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1151"	"127.5"	"7.28"	"291.23"	"3.09"	"1"	"1"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00400, Pf08366, Pf08596"	"134957"	"ENSG00000164506"	"STXBP5"	"hsa:134957; Q14DF3; Q5T5C0; Q5T5C1; Q5T5C2; Q8NBG8; Q96NG9"	""	""	"0"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"3.8"	"1.6"	"4.1"	"18.7"	"38.7"	"70.7"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60783"	"28S ribosomal protein S14, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS14 PE=1 SV=1"	"12"	"1"	"2"	"1"	"128"	"15.1"	"11.41"	"386.41"	"3.09"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf00253"	"63931"	"ENSG00000120333"	"MRPS14"	"hsa:63931; O60783; Q5R358"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62873"	"Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 OS=Homo sapiens OX=9606 GN=GNB1 PE=1 SV=3"	"4"	"1"	"2"	"1"	"340"	"37.4"	"6.00"	"264.90"	"3.09"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00400"	"2782"	"ENSG00000078369"	"GNB1"	"B1AJZ7; hsa:2782; P04697; P04901; P62873; Q1RMY8"	"Nicotine effect on dopaminergic neurons; Thyroid stimulating hormone (TSH) signaling pathway; Corticotropin-releasing hormone signaling pathway; Myometrial relaxation and contraction pathways; G protein signaling pathways; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Ras signaling; 1p36 copy number variation syndrome; Calcium regulation in cardiac cells; Estrogen signaling pathway"	"G alpha (q) signalling events; G alpha (12/13) signalling events; Olfactory Signaling Pathway; G alpha (i) signalling events; G alpha (z) signalling events; Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1); ADP signalling through P2Y purinoceptor 12; Extra-nuclear estrogen signaling; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production; Sensory perception of sweet, bitter, and umami (glutamate) taste; Thrombin signalling through proteinase activated receptors (PARs); Activation of G protein gated Potassium channels; G-protein activation; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; G beta:gamma signalling through PI3Kgamma; Prostacyclin signalling through prostacyclin receptor; Adrenaline,noradrenaline inhibits insulin secretion; Ca2+ pathway; G beta:gamma signalling through PLC beta; ADP signalling through P2Y purinoceptor 1; Glucagon-type ligand receptors; Thromboxane signalling through TP receptor; Vasopressin regulates renal water homeostasis via Aquaporins; Presynaptic function of Kainate receptors; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; G beta:gamma signalling through BTK; G beta:gamma signalling through CDC42; Inhibition  of voltage gated Ca2+ channels via Gbeta/gamma subunits; Inactivation, recovery and regulation of the phototransduction cascade; Glucagon signaling in metabolic regulation; Activation of the phototransduction cascade"	"45"	"0"	"3.1"	"4.8"	"7.5"	"6.9"	"6.3"	"6.6"	"7.6"	"10.1"	"36.0"	"85.7"	"143.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92615"	"La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3"	"3"	"2"	"3"	"2"	"738"	"80.5"	"6.92"	"941.83"	"3.09"	"2"	"1"	"other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity"	"Pf05383"	"23185"	"ENSG00000107929"	"LARP4B"	"A7MD20; hsa:23185; Q5T3R3; Q5T3R4; Q5T3R5; Q68CY4; Q92615"	""	""	"0"	"0"	"163.4"	"153.5"	"180.0"	"147.0"	"161.2"	"175.5"	"195.0"	"204.4"	"298.9"	"419.6"	"543.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBF8"	"Phosphatidylinositol 4-kinase beta OS=Homo sapiens OX=9606 GN=PI4KB PE=1 SV=1"	"1"	"1"	"2"	"1"	"816"	"91.3"	"6.25"	"418.06"	"3.09"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport;signal transduction"	"other membranes;cytosol;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf00454"	"5298"	"ENSG00000143393"	"PI4KB"	"B4DGI2; hsa:5298; O15096; P78405; Q5VWB9; Q5VWC0; Q5VWC1; Q9BWR6; Q9UBF8"	""	"Synthesis of PIPs at the Golgi membrane"	"1"	"0"	"3.6"	"6.4"	"7.5"	"4.2"	"4.7"	"5.0"	"6.3"	"10.9"	"19.4"	"44.6"	"70.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08195"	"4F2 cell-surface antigen heavy chain OS=Homo sapiens OX=9606 GN=SLC3A2 PE=1 SV=3"	"2"	"1"	"2"	"1"	"630"	"68.0"	"5.01"	"525.61"	"3.08"	"1"	"1"	"other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;nucleus;other cytoplasmic organelle;other cell component"	"transporter activity;nucleic acid binding activity"	"Pf00128, Pf16028"	"6520"	"ENSG00000168003"	"SLC3A2"	"hsa:6520; J3KPF3; P08195; Q13543"	"mRNA, protein, and metabolite inducation pathway by cyclosporin A; Ferroptosis; Proximal tubule transport; Pleural mesothelioma"	"Tryptophan catabolism; Basigin interactions; Amino acid transport across the plasma membrane; Defective SLC7A7 causes lysinuric protein intolerance (LPI)"	"8"	"0"	"10.3"	"14.6"	"10.5"	"11.7"	"10.2"	"10.0"	"14.9"	"14.0"	"45.9"	"89.5"	"132.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H2K0"	"Translation initiation factor IF-3, mitochondrial OS=Homo sapiens OX=9606 GN=MTIF3 PE=1 SV=4"	"5"	"1"	"2"	"1"	"278"	"31.7"	"9.69"	"448.98"	"3.08"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"mitochondrion"	"translation activity;nucleic acid binding activity"	"Pf05198"	"219402"	"ENSG00000122033"	"MTIF3"	"hsa:219402; Q05BL8; Q5W0V0; Q86X68; Q9H2K0"	""	"Mitochondrial translation initiation"	"1"	"0"	"174.4"	"128.3"	"169.1"	"154.4"	"165.9"	"180.1"	"197.2"	"197.9"	"430.3"	"542.0"	"379.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43159"	"Ribosomal RNA-processing protein 8 OS=Homo sapiens OX=9606 GN=RRP8 PE=1 SV=2"	"3"	"1"	"2"	"1"	"456"	"50.7"	"9.42"	"309.20"	"3.08"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf05148"	"23378"	"ENSG00000132275"	"RRP8"	"hsa:23378; O43159; Q7KZ78; Q9BVM6"	""	"SIRT1 negatively regulates rRNA expression"	"1"	"0"	"6.5"	"4.3"	"4.8"	"2.8"	"4.7"	"5.0"	"8.7"	"9.5"	"49.1"	"61.4"	"60.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95568"	"Histidine protein methyltransferase 1 homolog OS=Homo sapiens OX=9606 GN=METTL18 PE=1 SV=1"	"3"	"1"	"2"	"1"	"372"	"42.1"	"6.76"	"365.11"	"3.08"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf13489"	"92342"	"ENSG00000171806"	"METTL18"	"B2R9T5; hsa:92342; O95568"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q93075"	"Putative deoxyribonuclease TATDN2 OS=Homo sapiens OX=9606 GN=TATDN2 PE=1 SV=2"	"2"	"1"	"2"	"1"	"761"	"85.0"	"7.39"	"368.71"	"3.08"	"1"	"1"	""	"nucleus"	"other molecular function"	"Pf01026"	"9797"	"ENSG00000157014"	"TATDN2"	"hsa:9797; Q3MIL9; Q5BKU0; Q93075"	""	"XBP1(S) activates chaperone genes"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P38398"	"Breast cancer type 1 susceptibility protein OS=Homo sapiens OX=9606 GN=BRCA1 PE=1 SV=2"	"1"	"1"	"1"	"1"	"1863"	"207.6"	"5.41"	""	"3.07"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00097, Pf00533, Pf12820"	"672"	"ENSG00000012048"	"BRCA1"	"E9PFZ0; hsa:672; O15129; P38398; Q1RMC1; Q3LRJ0; Q3LRJ6; Q6IN79; Q7KYU9"	"Androgen receptor signaling pathway; miRNA regulation of DNA damage response; Glioblastoma signaling pathways; Hepatitis C and hepatocellular carcinoma; Pathways affected in adenoid cystic carcinoma; PI3K-Akt signaling pathway; Breast cancer pathway; DNA repair pathways, full network; Pleural mesothelioma; Nucleotide excision repair in xeroderma pigmentosum ; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; Primary ovarian insufficiency; 5q35 copy number variation; DNA damage response"	"Neddylation; KEAP1-NFE2L2 pathway; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Regulation of TP53 Activity through Phosphorylation; Metalloprotease DUBs; Processing of DNA double-strand break ends; TP53 Regulates Transcription of DNA Repair Genes; Meiotic synapsis; Resolution of D-loop Structures through Holliday Junction Intermediates; SUMOylation of DNA damage response and repair proteins; Transcriptional Regulation by E2F6; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; Meiotic recombination; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Nonhomologous End-Joining (NHEJ); Defective DNA double strand break response due to BRCA1 loss of function; Defective DNA double strand break response due to BARD1 loss of function"	"40"	"0"	"3.1"	"3.1"	"6.3"	"3.8"	"4.8"	"4.9"	"6.7"	"6.9"	"20.2"	"40.5"	"49.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UGP8"	"Translocation protein SEC63 homolog OS=Homo sapiens OX=9606 GN=SEC63 PE=1 SV=2"	"2"	"1"	"2"	"1"	"760"	"87.9"	"5.31"	"468.29"	"3.07"	"1"	"1"	"other metabolic processes;transport;developmental processes"	"other membranes;ER/Golgi"	"transporter activity;other molecular function"	"Pf00226, Pf02889"	"11231"	"ENSG00000025796"	"SEC63"	"hsa:11231; O95380; Q5THN4; Q86VS9; Q8IWL0; Q9NTE0; Q9UGP8"	""	""	"0"	"0"	"7.3"	"8.4"	"5.8"	"6.7"	"7.4"	"7.1"	"6.5"	"19.5"	"34.6"	"178.1"	"269.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96NW4"	"Ankyrin repeat domain-containing protein 27 OS=Homo sapiens OX=9606 GN=ANKRD27 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1050"	"116.9"	"6.87"	"435.93"	"3.07"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02204, Pf12796"	"84079"	"ENSG00000105186"	"ANKRD27"	"hsa:84079; Q71MF5; Q86UC3; Q8ND80; Q96NW4; Q9H0I4"	""	"RAB GEFs exchange GTP for GDP on RABs"	"1"	"0"	"35.4"	"36.6"	"29.0"	"26.6"	"31.0"	"30.4"	"30.9"	"45.1"	"87.8"	"138.3"	"172.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P56182"	"Ribosomal RNA processing protein 1 homolog A OS=Homo sapiens OX=9606 GN=RRP1 PE=1 SV=1"	"5"	"1"	"1"	"1"	"461"	"52.8"	"9.33"	""	"3.06"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf05997"	"8568"	"ENSG00000160214"	"RRP1"	"hsa:8568; P56182; Q9NST5"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y485"	"DmX-like protein 1 OS=Homo sapiens OX=9606 GN=DMXL1 PE=1 SV=3"	"1"	"1"	"2"	"1"	"3027"	"337.6"	"6.34"	"304.86"	"3.06"	"1"	"1"	"other biological processes"	"other cell component"	""	"Pf00400, Pf12234"	"1657"	"ENSG00000172869"	"DMXL1"	"hsa:1657; Q9Y485"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y6X2"	"E3 SUMO-protein ligase PIAS3 OS=Homo sapiens OX=9606 GN=PIAS3 PE=1 SV=2"	"2"	"1"	"2"	"1"	"628"	"68.0"	"7.69"	"286.78"	"3.05"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf02891, Pf14324"	"10401"	"ENSG00000131788"	"PIAS3"	"hsa:10401; Q9UFI3; Q9Y6X2"	"Androgen receptor signaling pathway; Prolactin signaling pathway; Interleukin-11 signaling pathway; Oncostatin M signaling pathway; EGF/EGFR signaling pathway; Regulatory circuits of the STAT3 signaling pathway; Interactions between immune cells and microRNAs in tumor microenvironment; TAR syndrome; Interferon type I signaling pathways"	"Formation of Incision Complex in GG-NER; SUMOylation of DNA replication proteins; SUMOylation of transcription cofactors; SUMOylation of intracellular receptors; SUMOylation of transcription factors; SUMOylation of immune response proteins"	"15"	"0"	"45.7"	"38.0"	"59.5"	"45.7"	"58.9"	"49.2"	"65.1"	"76.6"	"112.5"	"168.9"	"245.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NRF8"	"CTP synthase 2 OS=Homo sapiens OX=9606 GN=CTPS2 PE=1 SV=1"	"2"	"1"	"1"	"1"	"586"	"65.6"	"6.90"	""	"3.05"	""	"1"	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00117, Pf06418"	"56474"	"ENSG00000047230"	"CTPS2"	"B3KWM2; hsa:56474; Q9BRI0; Q9H809; Q9H8K9; Q9NRF8"	"Pyrimidine metabolism"	"Interconversion of nucleotide di- and triphosphates"	"2"	"0"	"6.9"	"2.9"	"8.2"	"4.4"	"7.0"	"7.6"	"10.4"	"10.4"	"28.4"	"123.8"	"189.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15796"	"Mothers against decapentaplegic homolog 2 OS=Homo sapiens OX=9606 GN=SMAD2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"467"	"52.3"	"6.58"	"346.43"	"3.05"	"1"	"1"	"cell-cell signaling;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf03165, Pf03166"	"4087"	"ENSG00000175387"	"SMAD2"	"hsa:4087; Q15796"	"Cell cycle; AGE/RAGE pathway; Endoderm differentiation; Mesodermal commitment pathway; Extracellular vesicle-mediated signaling in recipient cells; Mesodermal commitment pathway; Hypothesized pathways in pathogenesis of cardiovascular disease; Tgif disruption of Shh signaling; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition; Canonical and non-canonical TGF-B signaling; Chromosomal and microsatellite instability in colorectal cancer ; Epithelial to mesenchymal transition in colorectal cancer; Pancreatic adenocarcinoma pathway; Neovascularisation processes; Envelope proteins and their potential roles in EDMD physiopathology; Hippo signaling regulation pathways; Hepatitis B infection; TGF-beta receptor signaling in skeletal dysplasias; Regucalcin in proximal tubule epithelial kidney cells; Overlap between signal transduction pathways contributing to LMNA laminopathies; LDLRAD4 and what we know about it; Neuroinflammation and glutamatergic signaling; CCL18 signaling pathway; Progeria-associated lipodystrophy; Th17 cell differentiation pathway; GDNF signaling; Inflammatory bowel disease signaling; A network map of Macrophage-stimulating protein (MSP) signaling; TGF-beta receptor signaling"	"Ub-specific processing proteases; SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Downregulation of TGF-beta receptor signaling; Downregulation of SMAD2/3:SMAD4 transcriptional activity; Formation of axial mesoderm; FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes; Signaling by NODAL; FOXO-mediated transcription of cell cycle genes; Germ layer formation at gastrulation; Formation of definitive endoderm; Transcriptional regulation of pluripotent stem cells; Signaling by Activin; SMAD2/3 Phosphorylation Motif Mutants in Cancer; TGFBR1 KD Mutants in Cancer; SMAD4 MH2 Domain Mutants in Cancer; SMAD2/3 MH2 Domain Mutants in Cancer"	"47"	"0"	"41.2"	"33.3"	"48.5"	"35.6"	"40.9"	"44.2"	"52.9"	"87.3"	"195.1"	"293.3"	"336.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P12277"	"Creatine kinase B-type OS=Homo sapiens OX=9606 GN=CKB PE=1 SV=1"	"3"	"1"	"2"	"1"	"381"	"42.6"	"5.59"	"352.82"	"3.05"	"1"	"1"	"other metabolic processes;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00217, Pf02807"	"1152"	"ENSG00000166165"	"CKB"	"A8K236; B2R5R4; hsa:1152; P12277; Q2LE07; Q6FG40; Q9UC66"	""	"RND3 GTPase cycle; Creatine metabolism"	"2"	"0"	"69.7"	"77.4"	"83.4"	"77.0"	"61.7"	"55.1"	"92.9"	"122.3"	"188.2"	"348.5"	"649.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4E1"	"WASH complex subunit 2C OS=Homo sapiens OX=9606 GN=WASHC2C PE=1 SV=4"	"1"	"1"	"2"	"1"	"1320"	"144.8"	"4.79"	"334.25"	"3.05"	"1"	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75531"	"Barrier-to-autointegration factor OS=Homo sapiens OX=9606 GN=BANF1 PE=1 SV=1"	"13"	"1"	"2"	"1"	"89"	"10.1"	"6.09"	"417.72"	"3.05"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02961"	"8815"	"ENSG00000175334"	"BANF1"	"hsa:8815; O60558; O75531; Q6FGG7"	"Envelope proteins and their potential roles in EDMD physiopathology; Familial partial lipodystrophy; Progeria-associated lipodystrophy"	"Vpr-mediated nuclear import of PICs; 2-LTR circle formation; Integration of viral DNA into host genomic DNA; Autointegration results in viral DNA circles; APOBEC3G mediated resistance to HIV-1 infection; Nuclear Envelope Breakdown; Initiation of Nuclear Envelope (NE) Reformation"	"11"	"0"	"36.3"	"53.6"	"39.8"	"41.1"	"36.2"	"32.4"	"55.6"	"74.3"	"98.8"	"161.6"	"177.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86UX6"	"Serine/threonine-protein kinase 32C OS=Homo sapiens OX=9606 GN=STK32C PE=1 SV=1"	"2"	"1"	"2"	"1"	"486"	"55.0"	"6.61"	"279.85"	"3.04"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction"	""	"kinase activity;other molecular function"	"Pf00069"	"282974"	"ENSG00000165752"	"STK32C"	"hsa:282974; Q5T0Q5; Q86UE1; Q86UX6"	""	""	"0"	"0"	"7.6"	"6.9"	"4.6"	"6.8"	"7.3"	"3.8"	"7.0"	"9.2"	"104.0"	"149.6"	"195.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q969S3"	"Zinc finger protein 622 OS=Homo sapiens OX=9606 GN=ZNF622 PE=1 SV=1"	"6"	"2"	"3"	"2"	"477"	"54.2"	"6.15"	"874.89"	"3.04"	"2"	"1"	"signal transduction;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf12171, Pf12756"	"90441"	"ENSG00000173545"	"ZNF622"	"hsa:90441; Q969S3"	""	""	"0"	"0"	"4.5"	"3.1"	"4.6"	"7.1"	"5.3"	"4.2"	"4.7"	"6.4"	"13.5"	"27.8"	"72.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52732"	"Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1056"	"119.1"	"5.64"	"300.09"	"3.03"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225, Pf13931"	"3832"	"ENSG00000138160"	"KIF11"	"A0AV49; B2RMV3; hsa:3832; P52732; Q15716; Q5VWX0"	""	"COPI-dependent Golgi-to-ER retrograde traffic; MHC class II antigen presentation; Kinesins"	"3"	"0"	"6.2"	"4.4"	"5.9"	"5.8"	"7.9"	"5.6"	"5.8"	"8.5"	"29.4"	"43.1"	"49.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z569"	"BRCA1-associated protein OS=Homo sapiens OX=9606 GN=BRAP PE=1 SV=2"	"2"	"1"	"2"	"1"	"592"	"67.3"	"5.92"	"297.20"	"3.03"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02148, Pf07576, Pf13639"	"8315"	"ENSG00000089234"	"BRAP"	"B4DRM1; B9EGS8; hsa:8315; O43238; O75341; Q7Z569"	"Ras signaling"	"RAF activation; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Negative regulation of MAPK pathway"	"6"	"0"	"19.5"	"21.3"	"19.8"	"20.6"	"25.5"	"26.2"	"27.4"	"36.2"	"84.4"	"90.1"	"97.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52747"	"Zinc finger protein 143 OS=Homo sapiens OX=9606 GN=ZNF143 PE=1 SV=2"	"1"	"1"	"2"	"1"	"638"	"68.9"	"6.05"	"388.72"	"3.03"	"1"	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00096"	"7702"	"ENSG00000166478"	"ZNF143"	"A8K518; B4DLY5; E7ER34; hsa:7702; O75559; P52747; Q8WUK9"	"IL-18 signaling pathway"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 3 Promoter; RNA polymerase II transcribes snRNA genes"	"4"	"0"	"188.5"	"205.6"	"123.1"	"113.3"	"157.8"	"157.4"	"183.6"	"242.1"	"321.9"	"522.4"	"643.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O76003"	"Glutaredoxin-3 OS=Homo sapiens OX=9606 GN=GLRX3 PE=1 SV=2"	"2"	"1"	"2"	"1"	"335"	"37.4"	"5.39"	"336.42"	"3.03"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00085, Pf00462"	"10539"	"ENSG00000108010"	"GLRX3"	"B3KMP7; B3KMQ5; D3DRG2; hsa:10539; O76003; Q5JV01; Q96CE0; Q9P1B0; Q9P1B1"	""	"Iron uptake and transport"	"1"	"0"	"46.6"	"65.6"	"75.5"	"80.2"	"68.4"	"62.9"	"74.8"	"99.2"	"179.9"	"287.6"	"402.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IWV7"	"E3 ubiquitin-protein ligase UBR1 OS=Homo sapiens OX=9606 GN=UBR1 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1749"	"200.1"	"6.01"	"303.74"	"3.03"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf02207, Pf02617, Pf18995"	"197131"	"ENSG00000159459"	"UBR1"	"hsa:197131; O60708; O75492; Q14D45; Q68DN9; Q8IWV7; Q8IWY6; Q96JY4"	""	"Antigen processing: Ubiquitination & Proteasome degradation"	"1"	"0"	"14.7"	"23.2"	"19.7"	"13.0"	"16.8"	"11.2"	"21.8"	"27.0"	"28.9"	"62.7"	"93.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IYH5"	"ZZ-type zinc finger-containing protein 3 OS=Homo sapiens OX=9606 GN=ZZZ3 PE=1 SV=1"	"1"	"1"	"2"	"1"	"903"	"102.0"	"5.69"	"362.68"	"3.03"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00249, Pf00569"	"26009"	"ENSG00000036549"	"ZZZ3"	"B7WPC6; hsa:26009; Q6N004; Q6N070; Q8IYH5; Q8IYP0; Q8IYR1; Q8TEK4; Q9Y4U0"	""	"Formation of WDR5-containing histone-modifying complexes; HATs acetylate histones"	"2"	"0"	"23.3"	"16.6"	"32.7"	"28.6"	"19.5"	"27.7"	"32.2"	"38.7"	"76.7"	"159.1"	"208.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95983"	"Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1"	"10"	"2"	"4"	"2"	"291"	"32.8"	"5.34"	"1674.22"	"3.02"	"2"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01429, Pf14048, Pf16564"	"53615"	"ENSG00000071655"	"MBD3"	"A8K4B7; D6W5Z2; hsa:53615; O95983; Q6PIL9; Q6PJZ9; Q86XF4"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"HDACs deacetylate histones; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Potential therapeutics for SARS; Regulation of PTEN gene transcription; RNA Polymerase I Transcription Initiation; Regulation of TP53 Activity through Acetylation"	"7"	"0"	"280.1"	"266.8"	"323.7"	"267.2"	"298.2"	"303.5"	"382.5"	"395.5"	"515.3"	"943.6"	"1532.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95163"	"Elongator complex protein 1 OS=Homo sapiens OX=9606 GN=ELP1 PE=1 SV=3"	"1"	"1"	"1"	"1"	"1332"	"150.2"	"5.94"	""	"3.02"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04762"	"8518"	"ENSG00000070061"	"ELP1"	"hsa:8518; O95163; Q5JSV2; Q9H327; Q9UG87"	""	"HATs acetylate histones"	"1"	"0"	"9.3"	"9.6"	"16.9"	"12.8"	"14.5"	"10.7"	"14.9"	"24.6"	"46.9"	"146.6"	"271.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86WR7"	"Proline and serine-rich protein 2 OS=Homo sapiens OX=9606 GN=PROSER2 PE=1 SV=2"	"3"	"1"	"2"	"1"	"435"	"45.8"	"7.20"	"372.35"	"3.01"	"1"	"1"	""	""	""	"Pf15385"	"254427"	"ENSG00000148426"	"PROSER2"	"D3DRR8; hsa:254427; Q5W0J9; Q5W0K0; Q5W0K1; Q5W0K2; Q6PJC8; Q86WR7; Q8N317"	""	""	"0"	"0"	"14.5"	"12.2"	"14.9"	"15.8"	"12.9"	"11.5"	"18.0"	"22.1"	"34.2"	"45.3"	"60.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BZF9"	"Uveal autoantigen with coiled-coil domains and ankyrin repeats OS=Homo sapiens OX=9606 GN=UACA PE=1 SV=2"	"1"	"2"	"3"	"2"	"1416"	"162.4"	"7.03"	"604.24"	"3.01"	"2"	"1"	"other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus"	"cytoskeletal activity"	"Pf12796"	"55075"	"ENSG00000137831"	"UACA"	"G3XAG2; hsa:55075; Q14DD3; Q8N3B8; Q96NH6; Q9BZF9; Q9HCL1; Q9NWC6"	""	"Regulation of the apoptosome activity; RHOH GTPase cycle"	"2"	"0"	"58.2"	"46.1"	"57.3"	"46.3"	"55.3"	"64.0"	"64.6"	"116.2"	"232.5"	"379.4"	"500.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQ69"	"ADP-ribose glycohydrolase MACROD1 OS=Homo sapiens OX=9606 GN=MACROD1 PE=1 SV=2"	"3"	"1"	"2"	"1"	"325"	"35.5"	"9.51"	"449.06"	"3.01"	"1"	"1"	"protein metabolism;other metabolic processes;stress response"	"nucleus"	"other molecular function"	"Pf01661"	"28992"	"ENSG00000133315"	"MACROD1"	"hsa:28992; Q9BQ69; Q9UH96"	""	""	"0"	"0"	"19.3"	"18.8"	"21.9"	"22.1"	"27.7"	"16.3"	"28.1"	"53.3"	"155.4"	"307.1"	"322.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50995"	"Annexin A11 OS=Homo sapiens OX=9606 GN=ANXA11 PE=1 SV=1"	"2"	"1"	"2"	"1"	"505"	"54.4"	"7.65"	"247.43"	"3.01"	"1"	"1"	"cell cycle OR cell proliferation;transport;other biological processes"	"cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00191"	"311"	"ENSG00000122359"	"ANXA11"	"B4DVE7; hsa:311; P50995"	""	""	"0"	"0"	"11.5"	"8.7"	"11.7"	"5.8"	"15.4"	"15.0"	"13.8"	"19.9"	"41.3"	"124.1"	"279.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99728"	"BRCA1-associated RING domain protein 1 OS=Homo sapiens OX=9606 GN=BARD1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"777"	"86.6"	"8.72"	"251.18"	"3.01"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00023, Pf14835"	"580"	"ENSG00000138376"	"BARD1"	"F6MDH7; F6MDH8; F6MDH9; hsa:580; O43574; Q53SS5; Q99728"	"Retinoblastoma gene in cancer; Pleural mesothelioma; 5q35 copy number variation"	"UCH proteinases; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Regulation of TP53 Activity through Phosphorylation; Metalloprotease DUBs; Processing of DNA double-strand break ends; Resolution of D-loop Structures through Holliday Junction Intermediates; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Nonhomologous End-Joining (NHEJ); Defective DNA double strand break response due to BRCA1 loss of function; Defective DNA double strand break response due to BARD1 loss of function"	"23"	"0"	"23.7"	"23.3"	"35.9"	"29.5"	"33.7"	"25.1"	"35.7"	"34.8"	"74.5"	"137.2"	"137.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NZL9"	"Methionine adenosyltransferase 2 subunit beta OS=Homo sapiens OX=9606 GN=MAT2B PE=1 SV=1"	"4"	"1"	"2"	"1"	"334"	"37.5"	"7.36"	"357.28"	"3.00"	"1"	"1"	"other metabolic processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf04321"	"27430"	"ENSG00000038274"	"MAT2B"	"B2R5Y6; hsa:27430; Q1WAI7; Q27J92; Q3LIE8; Q567T7; Q6NYC7; Q9BS89; Q9H3E1; Q9NZL9; Q9UJ54"	"Trans-sulfuration pathway; One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways; Methionine de novo and salvage pathway; Methylation pathways"	"Ub-specific processing proteases; Methylation"	"7"	"0"	"35.1"	"32.3"	"55.1"	"43.0"	"48.1"	"36.3"	"52.1"	"56.0"	"97.3"	"218.9"	"385.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NC96"	"Adaptin ear-binding coat-associated protein 1 OS=Homo sapiens OX=9606 GN=NECAP1 PE=1 SV=2"	"7"	"2"	"3"	"1"	"275"	"29.7"	"6.80"	"606.80"	"2.99"	"2"	"1"	"transport"	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf07933"	"25977"	"ENSG00000089818"	"NECAP1"	"hsa:25977; Q2NL73; Q5XG95; Q6NWY6; Q8N153; Q8NC96; Q8NCB0; Q9BU52; Q9Y407"	""	"Cargo recognition for clathrin-mediated endocytosis; Golgi Associated Vesicle Biogenesis"	"3"	"1"	"139.7"	"118.7"	"131.9"	"115.2"	"160.4"	"303.9"	"901.1"	"2143.7"	"1317.6"	"1038.2"	"1052.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UL51"	"Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 OS=Homo sapiens OX=9606 GN=HCN2 PE=1 SV=3"	"4"	"1"	"1"	"1"	"889"	"96.9"	"8.97"	""	"2.99"	""	"1"	"cell-cell signaling;transport;other biological processes"	"plasma membrane;other membranes;other cell component"	"transporter activity;other molecular function"	"Pf00027, Pf00520, Pf08412"	"610"	"ENSG00000099822"	"HCN2"	"hsa:610; O60742; O60743; O75267; Q9UBS2; Q9UL51"	"Genes targeted by miRNAs in adipocytes"	"HCN channels"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NXE8"	"Pre-mRNA-splicing factor CWC25 homolog OS=Homo sapiens OX=9606 GN=CWC25 PE=1 SV=1"	"2"	"1"	"2"	"1"	"425"	"49.6"	"10.18"	"416.50"	"2.99"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf10197, Pf12542"	"54883"	"ENSG00000273559; ENSG00000276761"	"CWC25"	"A0JLM3; hsa:54883; Q68DK5; Q9NXE8"	"17q12 copy number variation syndrome"	"mRNA Splicing - Major Pathway"	"2"	"0"	"38.2"	"29.7"	"43.1"	"29.4"	"38.6"	"41.3"	"51.0"	"60.1"	"125.5"	"162.7"	"137.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19623"	"Spermidine synthase OS=Homo sapiens OX=9606 GN=SRM PE=1 SV=1"	"3"	"1"	"2"	"1"	"302"	"33.8"	"5.49"	"306.95"	"2.99"	"1"	"1"	"other metabolic processes;other biological processes"	"cytosol"	"other molecular function"	"Pf01564, Pf17284"	"6723"	"ENSG00000116649"	"SRM"	"B1AKP9; hsa:6723; P19623; Q15511"	"Methionine de novo and salvage pathway; Amino acid metabolism"	"Metabolism of polyamines"	"3"	"0"	"110.9"	"133.4"	"101.4"	"100.1"	"118.9"	"114.5"	"117.0"	"153.4"	"225.8"	"373.1"	"453.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HD42"	"Charged multivesicular body protein 1a OS=Homo sapiens OX=9606 GN=CHMP1A PE=1 SV=1"	"9"	"2"	"2"	"2"	"196"	"21.7"	"8.06"	"326.22"	"2.99"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf03357"	"5119"	"ENSG00000131165"	"CHMP1A"	"A2RU09; hsa:5119; Q14468; Q15779; Q96G31; Q9HD42"	""	"HCMV Late Events"	"1"	"0"	"74.7"	"61.2"	"99.7"	"87.1"	"93.6"	"94.5"	"104.4"	"140.7"	"633.5"	"1997.0"	"2683.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NVC6"	"Mediator of RNA polymerase II transcription subunit 17 OS=Homo sapiens OX=9606 GN=MED17 PE=1 SV=2"	"2"	"1"	"2"	"1"	"651"	"72.8"	"7.44"	"340.12"	"2.99"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf10156"	"9440"	"ENSG00000042429"	"MED17"	"B3KN07; hsa:9440; Q9HA81; Q9NVC6; Q9UNP7; Q9Y2W0; Q9Y660"	""	"PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; Generic Transcription Pathway"	"3"	"0"	"7.2"	"5.5"	"7.6"	"3.2"	"7.6"	"5.9"	"9.0"	"9.1"	"25.9"	"58.1"	"90.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q969R5"	"Lethal(3)malignant brain tumor-like protein 2 OS=Homo sapiens OX=9606 GN=L3MBTL2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"705"	"79.1"	"6.84"	"374.53"	"2.98"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"nucleus"	"other molecular function"	"Pf02820"	"83746"	"ENSG00000100395"	"L3MBTL2"	"hsa:83746; Q8TEN1; Q969R5; Q96SC4; Q9BQI2; Q9UGS4"	""	"SUMOylation of chromatin organization proteins; Transcriptional Regulation by E2F6"	"2"	"0"	"36.3"	"32.2"	"35.5"	"35.2"	"37.1"	"34.8"	"39.2"	"53.1"	"110.9"	"239.3"	"375.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92989"	"Polyribonucleotide 5'-hydroxyl-kinase Clp1 OS=Homo sapiens OX=9606 GN=CLP1 PE=1 SV=1"	"3"	"1"	"2"	"1"	"425"	"47.6"	"6.62"	"349.78"	"2.98"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus"	"kinase activity;other molecular function"	"Pf06807, Pf16573, Pf16575"	"10978"	"ENSG00000172409"	"CLP1"	"B2R7J6; B4DTI8; hsa:10978; Q92989"	"mRNA processing"	"tRNA processing in the nucleus; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"6"	"0"	"9.6"	"17.7"	"12.0"	"8.5"	"11.5"	"10.9"	"13.3"	"12.9"	"29.9"	"45.7"	"88.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P78332"	"RNA-binding protein 6 OS=Homo sapiens OX=9606 GN=RBM6 PE=1 SV=5"	"1"	"1"	"2"	"1"	"1123"	"128.6"	"6.32"	"532.16"	"2.97"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf01585, Pf17780"	"10180"	"ENSG00000004534"	"RBM6"	"B4E0G6; hsa:10180; O60549; O75524; P78332; Q86SS3"	""	""	"0"	"0"	"81.1"	"95.5"	"95.0"	"83.8"	"89.8"	"81.5"	"94.0"	"115.3"	"156.4"	"181.3"	"226.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09669"	"Cytochrome c oxidase subunit 6C OS=Homo sapiens OX=9606 GN=COX6C PE=1 SV=2"	"11"	"1"	"2"	"1"	"75"	"8.8"	"10.39"	"306.72"	"2.97"	"1"	"1"	"other metabolic processes"	"other membranes;mitochondrion"	""	"Pf02937"	"1345"	"ENSG00000164919"	"COX6C"	"B2R4D7; hsa:1345; P09669"	"Electron transport chain: OXPHOS system in mitochondria; Ciliary landscape; Nonalcoholic fatty liver disease; Mitochondrial complex IV assembly; 5q35 copy number variation"	"TP53 Regulates Metabolic Genes; Respiratory electron transport; Cytoprotection by HMOX1"	"8"	"0"	"83.2"	"93.9"	"85.7"	"77.9"	"83.3"	"75.4"	"74.8"	"92.8"	"289.2"	"943.5"	"1512.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P85037"	"Forkhead box protein K1 OS=Homo sapiens OX=9606 GN=FOXK1 PE=1 SV=1"	"2"	"1"	"2"	"1"	"733"	"75.4"	"9.32"	"356.84"	"2.97"	"1"	"1"	"other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00250, Pf00498"	"221937"	"ENSG00000164916"	"FOXK1"	"hsa:221937; P85037"	""	"UCH proteinases"	"1"	"0"	"18.8"	"17.8"	"22.6"	"25.9"	"18.6"	"11.5"	"25.5"	"23.0"	"42.7"	"83.7"	"152.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O76031"	"ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial OS=Homo sapiens OX=9606 GN=CLPX PE=1 SV=2"	"2"	"1"	"2"	"1"	"633"	"69.2"	"7.58"	"273.74"	"2.97"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;cytosol;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf07724, Pf10431"	"10845"	"ENSG00000166855"	"CLPX"	"A1L428; A8K8F1; B9EGI8; hsa:10845; O76031; Q9H4D9"	""	""	"0"	"0"	"36.4"	"34.6"	"42.2"	"26.1"	"40.4"	"34.8"	"43.2"	"58.8"	"221.8"	"334.7"	"359.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11274"	"Breakpoint cluster region protein OS=Homo sapiens OX=9606 GN=BCR PE=1 SV=2"	"1"	"1"	"2"	"1"	"1271"	"142.7"	"7.03"	"282.01"	"2.97"	"1"	"1"	"cell adhesion;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00168, Pf00620, Pf00621, Pf09036, Pf19057"	"613"	"ENSG00000186716"	"BCR"	"hsa:613; P11274; P78501; Q12842; Q4LE80; Q6NZI3"	"Imatinib and chronic myeloid leukemia; Extrafollicular and follicular B cell activation by SARS-CoV-2"	"RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOB GTPase cycle; Signaling by cytosolic FGFR1 fusion mutants; Signaling by FGFR1 in disease"	"11"	"0"	"14.2"	"15.7"	"17.1"	"10.0"	"11.8"	"12.0"	"18.4"	"25.9"	"63.3"	"163.8"	"227.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NR33"	"DNA polymerase epsilon subunit 4 OS=Homo sapiens OX=9606 GN=POLE4 PE=1 SV=2"	"9"	"1"	"1"	"1"	"117"	"12.2"	"4.92"	""	"2.97"	""	"1"	"DNA metabolism;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00808"	"56655"	"ENSG00000115350"	"POLE4"	"hsa:56655; Q53TR2; Q9NR33"	"Pyrimidine metabolism; Base excision repair; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Activation of the pre-replicative complex; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; DNA replication initiation; Gap-filling DNA repair synthesis and ligation in GG-NER"	"16"	"0"	"8.2"	"12.9"	"9.4"	"11.1"	"10.3"	"7.7"	"11.8"	"16.6"	"28.7"	"55.8"	"92.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IYW5"	"E3 ubiquitin-protein ligase RNF168 OS=Homo sapiens OX=9606 GN=RNF168 PE=1 SV=1"	"2"	"1"	"2"	"1"	"571"	"65.0"	"7.96"	"334.52"	"2.97"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf14447"	"165918"	"ENSG00000163961"	"RNF168"	"hsa:165918; Q8IYW5; Q8NA67; Q96NS4"	"ATM signaling in development and disease ; 3q29 copy number variation syndrome; NIPBL role in DNA damage - Cornelia de Lange syndrome"	"SUMOylation of DNA damage response and repair proteins; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; Nonhomologous End-Joining (NHEJ)"	"8"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q4KWH8"	"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 OS=Homo sapiens OX=9606 GN=PLCH1 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1693"	"189.1"	"7.74"	"443.03"	"2.97"	"1"	"1"	"other metabolic processes;transport;signal transduction"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00168, Pf00387, Pf00388, Pf09279"	"23007"	"ENSG00000114805"	"PLCH1"	"hsa:23007; Q29RV9; Q4KWH8; Q4KWH9; Q68CN0; Q86XK4; Q9H9U2; Q9UPT3"	"Mesodermal commitment pathway; GPR40 pathway"	"Synthesis of IP3 and IP4 in the cytosol"	"3"	"0"	"28.8"	"13.2"	"27.9"	"41.7"	"27.3"	"34.0"	"36.4"	"32.7"	"42.6"	"57.5"	"105.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82932"	"28S ribosomal protein S6, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS6 PE=1 SV=3"	"10"	"1"	"2"	"1"	"125"	"14.2"	"9.26"	"413.48"	"2.96"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf01250"	"64968"	"ENSG00000243927"	"MRPS6"	"B2R573; hsa:64968; P82932; Q96Q64; Q9BSK8; Q9BW89"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01664"	"Transcription factor AP-4 OS=Homo sapiens OX=9606 GN=TFAP4 PE=1 SV=2"	"2"	"1"	"2"	"1"	"338"	"38.7"	"5.87"	"265.95"	"2.96"	"1"	"1"	"cell organization and biogenesis;stress response;signal transduction;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00010"	"7023"	"ENSG00000090447"	"TFAP4"	"hsa:7023; O60409; Q01664"	"DYRK1A involvement regarding cell proliferation in brain development"	""	"1"	"0"	"267.4"	"249.0"	"253.2"	"212.6"	"231.2"	"231.2"	"276.8"	"304.5"	"349.5"	"451.6"	"568.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07602"	"Prosaposin OS=Homo sapiens OX=9606 GN=PSAP PE=1 SV=2"	"2"	"1"	"2"	"1"	"524"	"58.1"	"5.17"	"347.83"	"2.96"	"1"	"1"	"other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02199, Pf03489, Pf05184"	"5660"	"ENSG00000197746"	"PSAP"	"hsa:5660; P07292; P07602; P15793; P78538; P78541; P78546; P78547; P78558; Q53Y86; Q6IBQ6; Q92739; Q92740; Q92741; Q92742"	"Degradation pathway of sphingolipids, including diseases"	"Neutrophil degranulation; Glycosphingolipid metabolism; G alpha (i) signalling events; Platelet degranulation ; Peptide ligand-binding receptors"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UPN4"	"Centrosomal protein of 131 kDa OS=Homo sapiens OX=9606 GN=CEP131 PE=1 SV=3"	"2"	"2"	"3"	"2"	"1083"	"122.1"	"8.69"	"561.19"	"2.95"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	""	"22994"	"ENSG00000141577"	"CEP131"	"A6NHI8; B2RN11; hsa:22994; Q96F50; Q9UPN4"	""	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"7"	"0"	"51.6"	"38.3"	"60.0"	"53.1"	"71.6"	"59.2"	"66.8"	"83.0"	"125.5"	"207.6"	"258.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23378"	"Glycine dehydrogenase (decarboxylating), mitochondrial OS=Homo sapiens OX=9606 GN=GLDC PE=1 SV=2"	"1"	"1"	"1"	"1"	"1020"	"112.7"	"7.11"	""	"2.95"	""	"1"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01212, Pf02347"	"2731"	"ENSG00000178445"	"GLDC"	"hsa:2731; P23378; Q2M2F8"	"Metabolic Epileptic Disorders"	"Glycine degradation"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13526"	"Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 OS=Homo sapiens OX=9606 GN=PIN1 PE=1 SV=1"	"9"	"1"	"2"	"1"	"163"	"18.2"	"8.82"	"338.65"	"2.95"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00397, Pf00639"	"5300"	"ENSG00000127445"	"PIN1"	"A8K4V9; hsa:5300; Q13526; Q53X75"	"Novel intracellular components of RIG-I-like receptor pathway"	"Regulation of TP53 Activity through Phosphorylation; ISG15 antiviral mechanism; Negative regulators of DDX58/IFIH1 signaling; PI5P Regulates TP53 Acetylation; RHO GTPases Activate NADPH Oxidases"	"6"	"0"	"90.4"	"71.1"	"84.7"	"64.2"	"76.4"	"92.8"	"92.6"	"128.9"	"303.7"	"586.8"	"984.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H1K1"	"Iron-sulfur cluster assembly enzyme ISCU, mitochondrial OS=Homo sapiens OX=9606 GN=ISCU PE=1 SV=2"	"5"	"1"	"2"	"1"	"167"	"18.0"	"9.48"	"398.86"	"2.95"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01592"	"23479"	"ENSG00000136003"	"ISCU"	"hsa:23479; Q6P713; Q99617; Q9H1K1; Q9H1K2"	"Iron-sulfur cluster biogenesis"	"Maturation of replicase proteins"	"2"	"0"	"39.5"	"26.1"	"38.5"	"30.0"	"38.5"	"34.9"	"49.1"	"58.4"	"131.5"	"262.3"	"323.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H6S0"	"3'-5' RNA helicase YTHDC2 OS=Homo sapiens OX=9606 GN=YTHDC2 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1430"	"160.1"	"8.40"	"293.15"	"2.95"	"1"	"1"	"cell cycle OR cell proliferation;other biological processes"	"ER/Golgi;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf01424, Pf04146, Pf04408, Pf07717"	"64848"	"ENSG00000047188"	"YTHDC2"	"B2RP66; hsa:64848; Q9H6S0"	""	""	"0"	"0"	"16.7"	"16.5"	"21.3"	"15.2"	"15.4"	"16.2"	"18.6"	"33.4"	"29.9"	"73.8"	"135.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75146"	"Huntingtin-interacting protein 1-related protein OS=Homo sapiens OX=9606 GN=HIP1R PE=1 SV=2"	"1"	"1"	"2"	"1"	"1068"	"119.3"	"6.67"	"311.48"	"2.95"	"1"	"1"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01608, Pf07651, Pf16515"	"9026"	"ENSG00000130787"	"HIP1R"	"A6NHQ6; hsa:9026; O75146; Q6NXG8; Q9UED9"	"5q35 copy number variation"	"Clathrin-mediated endocytosis; Golgi Associated Vesicle Biogenesis"	"3"	"0"	"3.7"	"4.0"	"2.5"	"1.8"	"2.9"	"4.3"	"4.1"	"12.5"	"30.2"	"40.1"	"51.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NR48"	"Histone-lysine N-methyltransferase ASH1L OS=Homo sapiens OX=9606 GN=ASH1L PE=1 SV=2"	"1"	"2"	"3"	"2"	"2969"	"332.6"	"9.39"	"823.44"	"2.95"	"2"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00439, Pf00856, Pf01426, Pf17907"	"55870"	"ENSG00000116539"	"ASH1L"	"hsa:55870; Q59GP1; Q5T714; Q5T715; Q9NR48; Q9P2C7"	"Histone modifications"	"PKMTs methylate histone lysines"	"2"	"0"	"6.4"	"4.5"	"11.2"	"6.0"	"4.0"	"6.7"	"7.2"	"9.7"	"16.3"	"30.2"	"31.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46020"	"Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform OS=Homo sapiens OX=9606 GN=PHKA1 PE=1 SV=2"	"2"	"1"	"1"	"1"	"1223"	"137.2"	"6.19"	""	"2.94"	""	"1"	"other metabolic processes"	"plasma membrane;other membranes;cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00723, Pf19292"	"5255"	"ENSG00000067177"	"PHKA1"	"B7ZL05; B7ZL07; hsa:5255; P46020; Q2M3D7"	"Glycogen synthesis and degradation"	"Glycogen breakdown (glycogenolysis)"	"2"	"0"	"5.2"	"3.8"	"7.0"	"6.0"	"5.1"	"4.7"	"9.9"	"10.2"	"33.1"	"60.1"	"81.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q969J3"	"BLOC-1-related complex subunit 5 OS=Homo sapiens OX=9606 GN=BORCS5 PE=1 SV=1"	"6"	"1"	"1"	"1"	"196"	"22.2"	"6.35"	""	"2.94"	""	"1"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf10158"	"118426"	"ENSG00000165714; ENSG00000280689"	"BORCS5"	"hsa:118426; Q969J3; Q96QS5"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H7D7"	"WD repeat-containing protein 26 OS=Homo sapiens OX=9606 GN=WDR26 PE=1 SV=3"	"2"	"1"	"1"	"1"	"661"	"72.1"	"6.16"	""	"2.94"	""	"1"	"protein metabolism;other metabolic processes"	"cytosol;mitochondrion;nucleus;other cell component"	""	"Pf00400, Pf17814"	"80232"	"ENSG00000162923"	"WDR26"	"A0MNN3; hsa:80232; Q4G100; Q59EC4; Q5GLZ9; Q86UY4; Q9H3C2; Q9H7D7"	"Ciliary landscape"	""	"1"	"0"	"9.5"	"13.4"	"12.3"	"7.1"	"13.1"	"6.7"	"11.2"	"23.5"	"34.1"	"60.7"	"119.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00217"	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS8 PE=1 SV=1"	"4"	"1"	"2"	"1"	"210"	"23.7"	"6.34"	"338.21"	"2.94"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;stress response;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf12838"	"4728"	"ENSG00000110717"	"NDUFS8"	"B2RB86; hsa:4728; O00217; Q0VDA8"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"46.4"	"33.4"	"61.7"	"44.9"	"45.2"	"46.8"	"60.9"	"82.1"	"273.5"	"668.0"	"822.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31930"	"Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3"	"2"	"1"	"2"	"1"	"480"	"52.6"	"6.37"	"390.67"	"2.94"	"1"	"1"	"other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00675, Pf05193"	"7384"	"ENSG00000010256"	"UQCRC1"	"B2R7R8; hsa:7384; P31930; Q96DD2"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex III assembly"	"Respiratory electron transport"	"4"	"0"	"14.0"	"19.2"	"15.9"	"10.6"	"13.2"	"12.1"	"17.1"	"27.3"	"36.8"	"64.5"	"76.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3U8"	"60S ribosomal protein L36 OS=Homo sapiens OX=9606 GN=RPL36 PE=1 SV=3"	"15"	"2"	"3"	"2"	"105"	"12.2"	"11.59"	"619.03"	"2.92"	"2"	"1"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus"	"other molecular function"	"Pf01158"	"25873"	"ENSG00000130255"	"RPL36"	"B2R4Y1; D6W634; hsa:25873; Q6FIG1; Q9UQF6; Q9Y3U8"	"Cytoplasmic ribosomal proteins"	"Major pathway of rRNA processing in the nucleolus and cytosol; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"127.3"	"139.8"	"140.5"	"121.4"	"135.6"	"137.6"	"161.3"	"239.3"	"529.9"	"1085.1"	"1670.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NWB7"	"Intraflagellar transport protein 57 homolog OS=Homo sapiens OX=9606 GN=IFT57 PE=1 SV=1"	"3"	"1"	"1"	"1"	"429"	"49.1"	"4.98"	""	"2.92"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"cytoskeleton;ER/Golgi;other cell component"	"nucleic acid binding activity"	"Pf10498"	"55081"	"ENSG00000114446"	"IFT57"	"hsa:55081; Q96DA9; Q9NWB7"	"Ciliary landscape; Genes related to primary cilium development (based on CRISPR); Ciliopathies; Bardet-Biedl syndrome"	"Intraflagellar transport; Hedgehog 'off' state"	"6"	"0"	"7.1"	"8.1"	"7.4"	"7.4"	"8.5"	"4.4"	"5.4"	"11.7"	"27.3"	"63.2"	"85.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5VT06"	"Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1"	"1"	"1"	"2"	"1"	"3117"	"350.7"	"6.33"	"531.17"	"2.92"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf01302, Pf14309"	"9857"	"ENSG00000135837"	"CEP350"	"hsa:9857; O75068; Q5VT06; Q8TDK3; Q8WY20"	"3q29 copy number variation syndrome"	""	"1"	"0"	"15.4"	"13.6"	"9.6"	"13.2"	"13.9"	"11.1"	"14.2"	"26.1"	"37.4"	"49.7"	"54.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q07889"	"Son of sevenless homolog 1 OS=Homo sapiens OX=9606 GN=SOS1 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1333"	"152.4"	"6.84"	"305.94"	"2.92"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00169, Pf00617, Pf00618, Pf00621"	"6654"	"ENSG00000115904"	"SOS1"	"A8K2G3; B4DXG2; hsa:6654; Q07889"	"IL-5 signaling pathway; Integrin-mediated cell adhesion; Leptin signaling pathway; Prolactin signaling pathway; Pilocytic astrocytoma; Androgen receptor network in prostate cancer; B cell receptor signaling pathway; TNF-alpha signaling pathway; Oncostatin M signaling pathway; Alpha 6 beta 4 signaling pathway; IL-3 signaling pathway; Kit receptor signaling pathway; Focal adhesion; Hepatocyte growth factor receptor signaling; RAC1/PAK1/p38/MMP2 pathway; IL6 signaling pathway; Hepatitis C and hepatocellular carcinoma; BDNF-TrkB signaling; Physico-chemical features and toxicity-associated pathways; MAPK signaling pathway; T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection; Angiopoietin-like protein 8 regulatory pathway; Chemokine signaling pathway; Embryonic stem cell pluripotency pathways; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; IL-4 signaling pathway; Endometrial cancer; PI3K-Akt signaling pathway; MAPK cascade; Ras signaling; Epithelial to mesenchymal transition in colorectal cancer; Non-small cell lung cancer; Breast cancer pathway; Acute viral myocarditis; Thermogenesis; EGF/EGFR signaling pathway; Envelope proteins and their potential roles in EDMD physiopathology; Fragile X syndrome; Gastrin signaling pathway; Hepatitis B infection; Melanoma; Thyroid hormones production and peripheral downstream signaling effects; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; IL-2 signaling pathway; MAPK pathway in congenital thyroid cancer; Pleural mesothelioma; Regulation of actin cytoskeleton; 4p16.3 copy number variation; 5q35 copy number variation; EPO receptor signaling; ErbB signaling pathway; T-cell receptor signaling pathway; DNA damage response (only ATM dependent)"	"Role of LAT2/NTAL/LAB on calcium mobilization; RET signaling; Downstream signal transduction; Tie2 Signaling; Signaling by CSF1 (M-CSF) in myeloid cells; FRS-mediated FGFR1 signaling; FRS-mediated FGFR2 signaling; FRS-mediated FGFR3 signaling; FRS-mediated FGFR4 signaling; FLT3 Signaling; Activated NTRK2 signals through FRS2 and FRS3; Signaling by FLT3 ITD and TKD mutants; FCERI mediated MAPK activation; FCERI mediated Ca+2 mobilization; Potential therapeutics for SARS; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; RAC1 GTPase cycle; NRAGE signals death through JNK; G alpha (12/13) signalling events; Interleukin receptor SHC signaling; RAF/MAP kinase cascade; DAP12 signaling; Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants; Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants; Signaling by PDGFRA extracellular domain mutants; Regulation of KIT signaling; SHC1 events in ERBB2 signaling; SHC1 events in ERBB4 signaling; GRB2 events in ERBB2 signaling; Signaling by ERBB2 KD Mutants; Signaling by ERBB2 TMD/JMD mutants; GRB2 events in EGFR signaling; SHC1 events in EGFR signaling; NCAM signaling for neurite out-growth; Signaling by FGFR1 in disease; SHC-mediated cascade:FGFR1; SHC-mediated cascade:FGFR2; Signaling by FGFR2 in disease; SHC-mediated cascade:FGFR3; SHC-mediated cascade:FGFR4; Signaling by FGFR3 in disease; Activation of RAC1; Erythropoietin activates RAS; Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; EGFR Transactivation by Gastrin; Constitutive Signaling by EGFRvIII; Signaling by ERBB2 ECD mutants; SOS-mediated signalling; Signalling to RAS; SHC-related events triggered by IGF1R; Signaling by FGFR4 in disease; MET activates RAS signaling; Activated NTRK2 signals through RAS; Activated NTRK3 signals through RAS; Constitutive Signaling by Overexpressed ERBB2; Signaling by FLT3 fusion proteins; Signal attenuation; GRB2:SOS provides linkage to MAPK signaling for Integrins ; Interleukin-15 signaling"	"115"	"0"	"26.9"	"23.1"	"22.7"	"21.4"	"26.9"	"29.8"	"49.3"	"114.0"	"314.9"	"594.2"	"830.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKA9"	"Polypyrimidine tract-binding protein 2 OS=Homo sapiens OX=9606 GN=PTBP2 PE=1 SV=1"	"5"	"2"	"3"	"1"	"531"	"57.5"	"8.66"	"1011.68"	"2.91"	"2"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf11835, Pf13893"	"58155"	"ENSG00000117569"	"PTBP2"	"hsa:58155; Q8N0Z1; Q8N160; Q8NFB0; Q8NFB1; Q969N9; Q96Q76; Q9UKA9"	"Genes targeted by miRNAs in adipocytes; mRNA processing"	""	"2"	"0"	"57.6"	"50.2"	"60.4"	"57.6"	"55.8"	"57.4"	"64.8"	"74.8"	"144.5"	"338.5"	"571.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75052"	"Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein OS=Homo sapiens OX=9606 GN=NOS1AP PE=1 SV=3"	"2"	"1"	"2"	"1"	"506"	"56.1"	"6.30"	"448.90"	"2.91"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00640"	"9722"	"ENSG00000198929"	"NOS1AP"	"B7ZLF5; hsa:9722; O43564; O75052; Q3T551; Q5VU95"	"Sudden infant death syndrome (SIDS) susceptibility pathways"	""	"1"	"0"	"75.7"	"54.6"	"65.0"	"65.8"	"70.8"	"77.0"	"81.4"	"83.8"	"175.9"	"263.1"	"310.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19532"	"Transcription factor E3 OS=Homo sapiens OX=9606 GN=TFE3 PE=1 SV=4"	"2"	"1"	"2"	"1"	"575"	"61.5"	"5.58"	"331.77"	"2.91"	"1"	"1"	"other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00010, Pf11851, Pf15951"	"7030"	"ENSG00000068323"	"TFE3"	"A8MZL6; hsa:7030; P19532; Q5JU74; Q92757; Q92758; Q99964"	"Type 2 papillary renal cell carcinoma; TGF-beta receptor signaling in skeletal dysplasias; Autophagy in pancreatic ductal adenocarcinoma; TGF-beta receptor signaling"	""	"4"	"0"	"58.5"	"45.9"	"42.6"	"35.7"	"49.7"	"55.4"	"53.3"	"67.3"	"101.3"	"158.2"	"205.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13137"	"Calcium-binding and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=CALCOCO2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"446"	"52.2"	"5.02"	"292.18"	"2.91"	"1"	"1"	"other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf17751"	"10241"	"ENSG00000136436"	"CALCOCO2"	"B2RBT0; B4DDC4; B4DDT4; B4DP36; B4E0C0; E7ENK0; E7ETP5; E9PBE5; hsa:10241; Q13137; Q53FQ5; Q53HB5; Q6IBN9; Q9BTF7"	""	""	"0"	"0"	"41.6"	"30.9"	"32.4"	"24.9"	"37.6"	"35.5"	"41.5"	"56.3"	"99.5"	"150.8"	"182.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P18206"	"Vinculin OS=Homo sapiens OX=9606 GN=VCL PE=1 SV=4"	"1"	"1"	"2"	"1"	"1134"	"123.7"	"5.66"	"271.60"	"2.90"	"1"	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01044"	"7414"	"ENSG00000035403"	"VCL"	"hsa:7414; P18206; Q16450; Q5SWX2; Q7Z3B8; Q8IXU7"	"Integrin-mediated cell adhesion; Primary focal segmental glomerulosclerosis (FSGS); Focal adhesion; VEGFA-VEGFR2 signaling; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Melanoma; Regulation of actin cytoskeleton"	"Neutrophil degranulation; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Platelet degranulation ; Signaling by BRAF and RAF1 fusions; Signaling by ALK fusions and activated point mutants; Smooth Muscle Contraction; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants"	"18"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00442"	"RNA 3'-terminal phosphate cyclase OS=Homo sapiens OX=9606 GN=RTCA PE=1 SV=1"	"3"	"1"	"2"	"1"	"366"	"39.3"	"7.85"	"258.29"	"2.90"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf01137, Pf05189"	"8634"	"ENSG00000137996"	"RTCA"	"hsa:8634; O00442; Q5VVL5; Q5VVL6; Q96E99"	""	""	"0"	"0"	"10.7"	"7.1"	"7.7"	"9.4"	"10.6"	"8.1"	"8.3"	"13.5"	"30.9"	"94.6"	"168.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NFT6"	"Protein DBF4 homolog B OS=Homo sapiens OX=9606 GN=DBF4B PE=1 SV=1"	"1"	"1"	"1"	"1"	"615"	"67.2"	"8.34"	""	"2.90"	""	"1"	"cell cycle OR cell proliferation;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf07535"	"80174"	"ENSG00000161692"	"DBF4B"	"D3DX56; hsa:80174; Q8NFT6; Q8TEX0; Q96B19; Q9H912"	""	""	"0"	"0"	"79.6"	"85.0"	"107.9"	"78.5"	"95.7"	"110.9"	"131.7"	"138.5"	"434.9"	"1328.0"	"2235.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5VSL9"	"Striatin-interacting protein 1 OS=Homo sapiens OX=9606 GN=STRIP1 PE=1 SV=1"	"1"	"1"	"1"	"1"	"837"	"95.5"	"6.29"	""	"2.90"	""	"1"	"cell organization and biogenesis;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf07923, Pf11882"	"85369"	"ENSG00000143093"	"STRIP1"	"hsa:85369; Q0V925; Q5VSL8; Q5VSL9; Q658K2; Q6ZV31; Q8N598; Q96SN2; Q9C0A2"	""	""	"0"	"0"	"18.0"	"15.4"	"18.5"	"17.5"	"17.8"	"24.2"	"21.9"	"22.4"	"46.6"	"93.0"	"128.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30622"	"CAP-Gly domain-containing linker protein 1 OS=Homo sapiens OX=9606 GN=CLIP1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1438"	"162.1"	"5.36"	"306.50"	"2.89"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01302, Pf16641"	"6249"	"ENSG00000130779"	"CLIP1"	"A0AVD3; hsa:6249; P30622; Q17RS4; Q29RG0"	"Microtubule cytoskeleton regulation; PAFAH1B1 copy number variation"	"RHO GTPases Activate Formins; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases activate IQGAPs; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"9"	"0"	"6.2"	"3.8"	"5.5"	"5.1"	"8.0"	"3.8"	"5.2"	"8.6"	"8.3"	"39.4"	"56.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55199"	"RNA polymerase II elongation factor ELL OS=Homo sapiens OX=9606 GN=ELL PE=1 SV=1"	"4"	"2"	"3"	"2"	"621"	"68.2"	"9.33"	"730.36"	"2.89"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf07303, Pf10390"	"8178"	"ENSG00000105656"	"ELL"	"hsa:8178; P55199"	"Interactome of polycomb repressive complex 2 (PRC2)"	"Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; Transcription-Coupled Nucleotide Excision Repair (TC-NER)"	"14"	"0"	"39.6"	"33.3"	"40.1"	"35.8"	"46.5"	"40.6"	"43.8"	"60.1"	"87.1"	"140.7"	"202.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NFI3"	"Cytosolic endo-beta-N-acetylglucosaminidase OS=Homo sapiens OX=9606 GN=ENGASE PE=1 SV=1"	"2"	"1"	"2"	"1"	"743"	"83.9"	"6.79"	"400.78"	"2.89"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol"	"other molecular function"	"Pf03644"	"64772"	"ENSG00000167280"	"ENGASE"	"hsa:64772; Q659F0; Q8NFI3; Q8TB86; Q9H6U4"	""	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"	"1"	"0"	"13.2"	"19.6"	"13.0"	"14.6"	"20.2"	"14.2"	"18.0"	"24.3"	"109.5"	"205.8"	"231.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NQT8"	"Kinesin-like protein KIF13B OS=Homo sapiens OX=9606 GN=KIF13B PE=1 SV=2"	"1"	"1"	"2"	"1"	"1826"	"202.7"	"5.88"	"334.86"	"2.89"	"1"	"1"	"transport;signal transduction;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225, Pf00498, Pf01302, Pf12423, Pf12473, Pf16183"	"23303"	"ENSG00000197892"	"KIF13B"	"B4DGY5; B5MC45; F8VPJ2; hsa:23303; O75134; Q9BYJ6; Q9NQT8"	""	"COPI-dependent Golgi-to-ER retrograde traffic; Kinesins"	"2"	"0"	"95.3"	"85.2"	"129.8"	"94.3"	"113.9"	"109.2"	"137.1"	"161.3"	"292.0"	"517.4"	"662.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5RKV6"	"Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1"	"3"	"1"	"2"	"1"	"272"	"28.2"	"6.28"	"307.32"	"2.89"	"1"	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	""	"Pf01138"	"118460"	"ENSG00000223496"	"EXOSC6"	"hsa:118460; Q5RKV6"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	"6"	"0"	"115.4"	"121.1"	"121.8"	"108.9"	"128.5"	"114.0"	"149.7"	"175.6"	"264.6"	"577.0"	"1092.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86T03"	"Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase OS=Homo sapiens OX=9606 GN=PIP4P1 PE=1 SV=1"	"4"	"1"	"2"	"1"	"277"	"29.5"	"8.91"	"305.43"	"2.88"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;nucleus;other cytoplasmic organelle"	"other molecular function"	"Pf09788"	"90809"	"ENSG00000165782"	"PIP4P1"	"B2RA35; hsa:90809; Q86T03; Q86U09; Q8WUC0; Q9BU67; Q9NSU8"	""	"PI5P Regulates TP53 Acetylation; Synthesis of PIPs in the nucleus"	"2"	"0"	"15.1"	"10.3"	"23.8"	"17.9"	"15.2"	"3.2"	"19.0"	"29.0"	"38.2"	"87.5"	"135.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31040"	"Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHA PE=1 SV=2"	"2"	"1"	"2"	"1"	"664"	"72.6"	"7.39"	"413.64"	"2.88"	"1"	"1"	"other metabolic processes;developmental processes"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf00890, Pf02910"	"6389"	"ENSG00000073578"	"SDHA"	"A8K5J6; B4DJ60; E9PBJ5; hsa:6389; P31040; Q16395; Q59GW8; Q8IW48; Q9UMY5"	"Electron transport chain: OXPHOS system in mitochondria; TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Nonalcoholic fatty liver disease; Mitochondrial complex II assembly; Arsenic metabolism and reactive oxygen species generation; TCA cycle (aka Krebs or citric acid cycle)"	"Respiratory electron transport; Citric acid cycle (TCA cycle)"	"9"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NR09"	"Baculoviral IAP repeat-containing protein 6 OS=Homo sapiens OX=9606 GN=BIRC6 PE=1 SV=2"	"0"	"1"	"2"	"1"	"4857"	"529.9"	"6.05"	"323.18"	"2.88"	"1"	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"19.6"	"16.3"	"19.8"	"15.9"	"24.0"	"18.6"	"21.0"	"30.4"	"45.1"	"79.0"	"104.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96HA1"	"Nuclear envelope pore membrane protein POM 121 OS=Homo sapiens OX=9606 GN=POM121 PE=1 SV=2"	"2"	"3"	"4"	"3"	"1249"	"127.6"	"10.56"	"859.04"	"2.88"	"3"	"1"	"transport"	"other membranes;ER/Golgi;nucleus"	"other molecular function"	"Pf15229"	"9883"	"ENSG00000196313"	"POM121"	"A6NFS9; A8CDT4; A8K933; A8MXF9; hsa:9883; O75115; Q96DI0; Q96HA1; Q9H9X1; Q9Y2N3; Q9Y4S7"	"Ciliary landscape"	"HCMV Early Events; HCMV Late Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Postmitotic nuclear pore complex (NPC) reformation"	"30"	"0"	"270.6"	"250.5"	"281.0"	"246.7"	"268.4"	"281.1"	"322.2"	"348.7"	"549.6"	"984.5"	"1426.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61599"	"N-alpha-acetyltransferase 20 OS=Homo sapiens OX=9606 GN=NAA20 PE=1 SV=1"	"8"	"1"	"2"	"1"	"178"	"20.4"	"5.03"	"323.50"	"2.88"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00583"	"51126"	"ENSG00000173418"	"NAA20"	"A6NHA3; B2R4G4; hsa:51126; P61599; Q5TFT7; Q9D7H8; Q9H0Y4; Q9NQH6; Q9Y6D2"	"Metapathway biotransformation Phase I and II"	""	"1"	"0"	"20.0"	"22.0"	"27.9"	"18.2"	"25.1"	"26.2"	"30.8"	"55.6"	"138.3"	"300.5"	"324.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43665"	"Regulator of G-protein signaling 10 OS=Homo sapiens OX=9606 GN=RGS10 PE=1 SV=3"	"6"	"1"	"1"	"1"	"181"	"21.2"	"7.49"	""	"2.88"	""	"1"	"cell-cell signaling;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00615"	"6001"	"ENSG00000148908"	"RGS10"	"A8K408; B1AMR8; hsa:6001; O43665; Q6IAZ6; Q96GN0"	"Mesodermal commitment pathway; Myometrial relaxation and contraction pathways; Calcium regulation in cardiac cells"	"G alpha (i) signalling events"	"4"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"2.5"	"3.0"	"17.7"	"59.6"	"128.8"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NRA8"	"Eukaryotic translation initiation factor 4E transporter OS=Homo sapiens OX=9606 GN=EIF4ENIF1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"985"	"108.1"	"8.32"	"264.61"	"2.87"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf10477"	"56478"	"ENSG00000184708"	"EIF4ENIF1"	"B1AKL2; B1AKL3; B2RBF1; hsa:56478; Q8NCF2; Q9H708; Q9NRA8"	"Primary ovarian insufficiency; 10q11.21q11.23 copy number variation syndrome"	""	"2"	"0"	"7.5"	"6.8"	"9.4"	"6.5"	"12.9"	"10.7"	"12.7"	"15.8"	"25.2"	"54.9"	"66.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H089"	"Large subunit GTPase 1 homolog OS=Homo sapiens OX=9606 GN=LSG1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"658"	"75.2"	"6.38"	"342.59"	"2.87"	"1"	"1"	"transport"	"cytosol;ER/Golgi;nucleus"	"other molecular function"	"Pf01926"	"55341"	"ENSG00000041802"	"LSG1"	"A0JLT4; A0PJK3; A6NI18; hsa:55341; Q7L9H8; Q9H089; Q9NUK8"	""	""	"0"	"0"	"48.3"	"38.5"	"59.6"	"57.3"	"64.2"	"60.5"	"74.8"	"75.7"	"153.7"	"294.0"	"393.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86XN8"	"RNA-binding protein MEX3D OS=Homo sapiens OX=9606 GN=MEX3D PE=1 SV=3"	"2"	"1"	"2"	"1"	"651"	"64.8"	"5.35"	"435.49"	"2.86"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf13920"	"399664"	"ENSG00000181588"	"MEX3D"	"A0PJL8; A1L023; E9PAL6; hsa:399664; Q71M49; Q86XN8"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P206"	"Uncharacterized protein KIAA1522 OS=Homo sapiens OX=9606 GN=KIAA1522 PE=1 SV=2"	"2"	"1"	"2"	"1"	"1035"	"107.0"	"9.73"	"390.68"	"2.86"	"1"	"1"	"other biological processes"	""	""	""	"57648"	"ENSG00000162522"	"KIAA1522"	"B4DQU8; B5MDY0; C9JH84; hsa:57648; Q8TCQ0; Q9P206"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75367"	"Core histone macro-H2A.1 OS=Homo sapiens OX=9606 GN=MACROH2A1 PE=1 SV=4"	"3"	"1"	"2"	"1"	"372"	"39.6"	"9.79"	"333.77"	"2.86"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00125, Pf01661, Pf16211"	"100394084; 100998964; 101131222; 101381952; 101564704; 101706296; 102008188; 102123677; 103079324; 104855290; 105467125; 105506940; 105531308; 105816031; 105869993; 108529540; 462076; 481514; 711836"	"ENSAMEG00000017887; ENSBMSG00010001156; ENSCAFG00000001076; ENSCAFG00020007175; ENSCAFG00030007355; ENSCAFG00040009734; ENSCANG00000022762; ENSCJAG00000005818; ENSCLAG00000016530; ENSCWAG00000001657; ENSFCAG00000013924; ENSGGOG00000001707; ENSLCNG00005003680; ENSMICG00000005677; ENSMLEG00000037795; ENSMMNG00015002866; ENSMNEG00000031666; ENSMPUG00000010011; ENSPANG00000002758; ENSPCOG00000013464; ENSPCTG00005011747; ENSPLOG00000000479; ENSPPAG00000029258; ENSPPYG00000015799; ENSPSMG00000021213; ENSPSNG00000019193; ENSPTRG00000017256; ENSRBIG00000034425; ENSRROG00000045755; ENSSBOG00000034640; ENSSSUG00005001976; ENSSVLG00005008251; ENSTGEG00000021330; ENSVVUG00000017487"	"H2afy; H2AFY; LOC100466888; LOC101338325; LOC101381952; LOC101564704; LOC102987354; LOC103079324; LOC103663804; LOC105869993; LOC106989149; LOC110591142; LOC111141291; LOC111182462; LOC112404331; LOC112625777; LOC112815157; LOC112861289; LOC112917035; LOC113928700; LOC114891795; LOC115516119; LOC116529369; LOC116750637; MACROH2A1"	"A0A091CNU6; A0A096N0E8; A0A2J8LRK8; A0A2J8VQ67; A0A2K5HRC8; A0A2K5W7N1; A0A2K5ZHE4; A0A2K6BUT6; A0A2K6EU20; A0A2K6LBL0; A0A2K6RXM8; A0A2K6UYW1; A0A2R9A926; A0A2U3WAW1; A0A2Y9IU30; A0A2Y9PFA0; A0A2Y9SS16; A0A340XJ26; A0A341BZA5; A0A3Q7NDG6; A0A3Q7S763; A0A484GVZ9; A0A485NYK5; A0A5S6R987; A0A667GC30; A0A673T0D7; A0A6G1ASZ6; A0A6J2AVA7; A0A6J2DX40; A0A6J3FC37; A0A6J3R528; A0A6P3F5E4; A0A6P6HX24; A0A8B7G616; A0A8C0C880; A0A8C0K484; A0A8C0S4U0; A0A8C2W4Z6; A0A8C3VQP8; A0A8C6F240; A0A8C8WAC0; A0A8C9AAB1; A0A8C9CK62; A0A8D2BC14; A0A8D2FWT2; A0A8I5UBU0; A0A8J8XTA7; A0A8M1F844; A0A8M1MQV0; A0A8P0N4A7; aju:106989149; cang:105506940; D2GVK3; dle:111182462; elk:111141291; F7HN69; G3QH59; G5BQ26; G7MUD7; ggo:101131222; H2QRI8; I2CUE9; lve:103079324; M3WJR3; M3YF29; mcf:102123677; mleu:105531308; mmur:105869993; mni:105467125; mpuf:101692673; nsu:110591142; oro:101381952; panu:100998964; pcad:102987354; pcoq:105816031; ptr:462076; rbb:108529540; sbq:101050376; umr:103663804; vvp:112917035; zca:113928700"	""	""	"0"	"0"	"106.1"	"83.8"	"115.8"	"98.3"	"106.3"	"104.0"	"137.4"	"161.5"	"325.8"	"609.5"	"780.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7L590"	"Protein MCM10 homolog OS=Homo sapiens OX=9606 GN=MCM10 PE=1 SV=2"	"3"	"2"	"3"	"2"	"875"	"98.1"	"8.75"	"706.15"	"2.86"	"2"	"1"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf09329, Pf09332"	"55388"	"ENSG00000065328"	"MCM10"	"A8K9I6; B7ZKZ8; hsa:55388; Q3MIR3; Q7L590; Q7LD55; Q96GX4; Q96NB6; Q9H0D7; Q9H3P9; Q9P177"	"Ciliary landscape; DNA replication"	"Activation of ATR in response to replication stress; Activation of the pre-replicative complex"	"4"	"0"	"83.6"	"51.1"	"78.5"	"80.0"	"97.5"	"82.1"	"99.7"	"111.1"	"176.1"	"248.3"	"281.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BRX2"	"Protein pelota homolog OS=Homo sapiens OX=9606 GN=PELO PE=1 SV=2"	"2"	"1"	"2"	"1"	"385"	"43.3"	"6.34"	"310.22"	"2.85"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;translation activity;other molecular function"	"Pf03463, Pf03464, Pf03465"	"53918"	"ENSG00000152684"	"PELO"	"hsa:53918; Q9BRX2; Q9GZS6; Q9Y306"	"Focal adhesion: PI3K-Akt-mTOR-signaling pathway"	""	"1"	"0"	"145.4"	"167.3"	"141.8"	"122.8"	"141.2"	"157.2"	"171.2"	"229.9"	"437.2"	"1102.1"	"1301.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82930"	"28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2"	"4"	"1"	"2"	"1"	"218"	"25.6"	"9.98"	"337.40"	"2.85"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf16053"	"65993"	"ENSG00000074071"	"MRPS34"	"hsa:65993; P82930; Q9BVI7"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"70.1"	"72.3"	"90.8"	"67.0"	"67.0"	"77.2"	"97.3"	"110.4"	"145.6"	"254.6"	"357.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UL03"	"Integrator complex subunit 6 OS=Homo sapiens OX=9606 GN=INTS6 PE=1 SV=1"	"1"	"1"	"2"	"1"	"887"	"100.3"	"8.62"	"305.11"	"2.85"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus"	"other molecular function"	"Pf13519, Pf15300"	"26512"	"ENSG00000102786"	"INTS6"	"hsa:26512; Q0P664; Q6PJP4; Q9UFK0; Q9UL03; Q9Y5M9"	""	"RNA polymerase II transcribes snRNA genes"	"1"	"0"	"19.6"	"20.4"	"22.8"	"24.5"	"20.1"	"20.2"	"27.5"	"37.5"	"43.4"	"76.3"	"124.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99536"	"Synaptic vesicle membrane protein VAT-1 homolog OS=Homo sapiens OX=9606 GN=VAT1 PE=1 SV=2"	"3"	"1"	"2"	"1"	"393"	"41.9"	"6.29"	"434.94"	"2.85"	"1"	"1"	"other biological processes"	"non-structural extracellular;other membranes;mitochondrion;other cytoplasmic organelle"	"other molecular function"	"Pf08240, Pf13602"	"10493"	"ENSG00000108828"	"VAT1"	"A8K345; B0AZP7; B4DPX4; hsa:10493; Q13035; Q5BKZ7; Q96A39; Q99536; Q9BUT8"	""	"Neutrophil degranulation"	"1"	"0"	"45.8"	"38.3"	"57.5"	"46.6"	"57.7"	"58.9"	"76.5"	"126.2"	"287.6"	"368.0"	"372.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30048"	"Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3"	"8"	"2"	"3"	"2"	"256"	"27.7"	"7.78"	"561.28"	"2.84"	"2"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00578, Pf10417"	"10935"	"ENSG00000165672"	"PRDX3"	"B2R7Z0; D3DRC9; E9PH29; hsa:10935; P30048; P35690; Q0D2H1; Q13776; Q5T5V2; Q96HK4"	"Selenium micronutrient network"	"Detoxification of Reactive Oxygen Species"	"2"	"0"	"71.3"	"69.1"	"92.8"	"85.4"	"100.3"	"91.6"	"97.9"	"135.9"	"246.0"	"507.2"	"741.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96FS4"	"Signal-induced proliferation-associated protein 1 OS=Homo sapiens OX=9606 GN=SIPA1 PE=1 SV=1"	"2"	"1"	"2"	"1"	"1042"	"112.1"	"6.60"	"361.27"	"2.84"	"1"	"1"	"cell organization and biogenesis;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity"	"Pf00595, Pf02145"	"6494"	"ENSG00000213445"	"SIPA1"	"hsa:6494; O14518; O60484; O60618; Q2YD83; Q96FS4"	"MAPK cascade"	"Rap1 signalling"	"2"	"0"	"25.4"	"27.9"	"32.9"	"29.2"	"36.3"	"25.2"	"46.5"	"50.9"	"98.3"	"206.8"	"255.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NE86"	"Calcium uniporter protein, mitochondrial OS=Homo sapiens OX=9606 GN=MCU PE=1 SV=1"	"3"	"1"	"2"	"1"	"351"	"39.8"	"8.65"	"335.74"	"2.84"	"1"	"1"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf04678"	"90550"	"ENSG00000156026"	"MCU"	"B2RDF3; B3KXV7; hsa:90550; Q8NE86; Q96FL3"	"Alzheimer's disease and miRNA effects; Pleural mesothelioma; Alzheimer's disease"	"Processing of SMDT1"	"5"	"0"	"18.8"	"15.1"	"13.4"	"15.4"	"25.8"	"16.1"	"20.3"	"26.0"	"40.7"	"65.8"	"99.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62910"	"60S ribosomal protein L32 OS=Homo sapiens OX=9606 GN=RPL32 PE=1 SV=2"	"7"	"1"	"2"	"1"	"135"	"15.9"	"11.33"	"285.18"	"2.84"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01655"	"6161"	"ENSG00000144713"	"RPL32"	"B2R4Q3; hsa:6161; P02433; P62910"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"33.1"	"29.9"	"41.4"	"38.9"	"41.7"	"38.3"	"55.4"	"95.2"	"185.9"	"343.6"	"546.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96B01"	"RAD51-associated protein 1 OS=Homo sapiens OX=9606 GN=RAD51AP1 PE=1 SV=1"	"3"	"1"	"2"	"1"	"352"	"38.4"	"9.11"	"316.23"	"2.83"	"1"	"1"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf15696"	"10635"	"ENSG00000111247"	"RAD51AP1"	"A8K7D3; hsa:10635; O43403; Q7Z779; Q96B01"	""	"Resolution of D-loop Structures through Holliday Junction Intermediates; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Homologous DNA Pairing and Strand Exchange; Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2"	"8"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N567"	"Zinc finger CCHC domain-containing protein 9 OS=Homo sapiens OX=9606 GN=ZCCHC9 PE=1 SV=2"	"5"	"1"	"2"	"1"	"271"	"30.5"	"9.17"	"407.33"	"2.83"	"1"	"1"	""	"nucleus"	"other molecular function"	"Pf00098"	"84240"	"ENSG00000131732"	"ZCCHC9"	"B2RAE7; hsa:84240; Q8N567; Q9H027"	""	""	"0"	"0"	"85.8"	"79.2"	"98.0"	"90.5"	"102.7"	"104.2"	"113.5"	"132.1"	"212.1"	"410.8"	"611.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IZ21"	"Phosphatase and actin regulator 4 OS=Homo sapiens OX=9606 GN=PHACTR4 PE=1 SV=1"	"2"	"1"	"2"	"1"	"702"	"78.2"	"6.62"	"433.56"	"2.83"	"1"	"1"	"cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf02755"	"65979"	"ENSG00000204138"	"PHACTR4"	"A2APK6; B9ZVW0; D3DPM3; hsa:65979; Q68DD4; Q6NUN6; Q8IZ21; Q8N384; Q9H395; Q9H6X0; Q9H8W6"	""	""	"0"	"0"	"7.7"	"6.0"	"13.5"	"5.1"	"8.4"	"8.8"	"12.5"	"6.8"	"28.7"	"99.7"	"235.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13371"	"Phosducin-like protein OS=Homo sapiens OX=9606 GN=PDCL PE=1 SV=3"	"6"	"1"	"2"	"1"	"301"	"34.3"	"4.73"	""	"2.83"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"cytosol;other cell component"	""	"Pf02114"	"5082"	"ENSG00000136940"	"PDCL"	"hsa:5082; Q13371; Q4VXB6; Q96AF1; Q9UEW7; Q9UFL0; Q9UNX1; Q9UNX2"	""	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"	"1"	"0"	"0.0"	"3.6"	"1.9"	"0.0"	"3.0"	"0.0"	"2.6"	"1.5"	"37.0"	"263.3"	"284.3"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5T440"	"Putative transferase CAF17, mitochondrial OS=Homo sapiens OX=9606 GN=IBA57 PE=1 SV=1"	"3"	"1"	"1"	"1"	"356"	"38.1"	"9.83"	""	"2.82"	""	"1"	"cell organization and biogenesis;other metabolic processes"	"mitochondrion"	"other molecular function"	""	"200205"	"ENSG00000181873"	"IBA57"	"hsa:200205; Q5T440"	""	""	"0"	"0"	"43.9"	"43.7"	"40.1"	"42.0"	"40.5"	"46.3"	"59.9"	"74.1"	"146.6"	"277.0"	"328.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N9N5"	"Protein BANP OS=Homo sapiens OX=9606 GN=BANP PE=1 SV=3"	"2"	"1"	"2"	"1"	"519"	"56.5"	"5.49"	"368.64"	"2.82"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf10523"	"54971"	"ENSG00000172530"	"BANP"	"A8MU25; A8MX25; B2RCF7; B4DNJ9; F5GZM0; hsa:54971; Q8N9N5; Q96GJ7; Q9NWY1"	""	"Regulation of TP53 Activity through Association with Co-factors"	"1"	"0"	"42.9"	"36.3"	"48.8"	"44.2"	"36.2"	"45.7"	"54.1"	"75.5"	"174.5"	"308.8"	"387.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46063"	"ATP-dependent DNA helicase Q1 OS=Homo sapiens OX=9606 GN=RECQL PE=1 SV=3"	"2"	"1"	"2"	"1"	"649"	"73.4"	"7.88"	"271.41"	"2.82"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf16124"	"5965"	"ENSG00000004700"	"RECQL"	"A8K6G2; hsa:5965; P46063"	"Progeria-associated lipodystrophy"	""	"1"	"0"	"13.1"	"13.9"	"13.2"	"10.5"	"13.4"	"10.9"	"10.0"	"21.0"	"48.3"	"73.7"	"98.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75880"	"Protein SCO1 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=SCO1 PE=1 SV=1"	"3"	"1"	"2"	"1"	"301"	"33.8"	"8.88"	"340.37"	"2.81"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"other membranes;cytoskeleton;mitochondrion"	"other molecular function"	"Pf02630"	"6341"	"ENSG00000133028"	"SCO1"	"B2RDM0; hsa:6341; O75880"	"Electron transport chain: OXPHOS system in mitochondria; Copper homeostasis"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"5"	"0"	"73.0"	"73.4"	"71.0"	"59.0"	"75.4"	"73.8"	"95.0"	"136.6"	"320.1"	"523.8"	"586.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00743"	"Serine/threonine-protein phosphatase 6 catalytic subunit OS=Homo sapiens OX=9606 GN=PPP6C PE=1 SV=1"	"3"	"1"	"2"	"1"	"305"	"35.1"	"5.69"	"241.67"	"2.80"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00149"	"5537"	"ENSG00000119414"	"PPP6C"	"B2R5V6; B7Z2W9; B7Z5K9; hsa:5537; O00743; Q5U0A2; Q9UIC9"	""	"Telomere Extension By Telomerase; COPII-mediated vesicle transport"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BTE6"	"Alanyl-tRNA editing protein Aarsd1 OS=Homo sapiens OX=9606 GN=AARSD1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"412"	"45.5"	"6.42"	"341.40"	"2.80"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other cell component"	"nucleic acid binding activity;other molecular function"	"Pf07973"	"100885850; 80755"	"ENSG00000108825; ENSG00000266967"	"AARSD1"	"B4DI73; hsa:100885850; hsa:80755; Q9BTE6"	""	""	"0"	"0"	"21.0"	"28.6"	"35.3"	"27.9"	"31.5"	"22.9"	"27.6"	"46.5"	"102.5"	"312.0"	"450.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H6U6"	"Breast carcinoma-amplified sequence 3 OS=Homo sapiens OX=9606 GN=BCAS3 PE=1 SV=3"	"2"	"1"	"2"	"1"	"928"	"101.2"	"6.70"	"356.07"	"2.80"	"1"	"1"	"cell-cell signaling;other metabolic processes;stress response;developmental processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf12490"	"54828"	"ENSG00000141376"	"BCAS3"	"hsa:54828; Q17RM0; Q6KF21; Q8IXI6; Q8NDR8; Q8TDL9; Q8TDM1; Q8WY55; Q9BVF0; Q9H6U6; Q9H957; Q9H9Y9; Q9NXP4"	"Ectoderm differentiation"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96TA2"	"ATP-dependent zinc metalloprotease YME1L1 OS=Homo sapiens OX=9606 GN=YME1L1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"773"	"86.4"	"8.76"	"438.91"	"2.79"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf00004, Pf01434, Pf17862"	"10730"	"ENSG00000136758"	"YME1L1"	"B4DNM1; D3DRV8; D3DRV9; hsa:10730; Q5T8D9; Q96TA2; Q9H1Q0; Q9UMR9"	""	"Processing of SMDT1"	"1"	"0"	"21.6"	"23.2"	"25.9"	"30.2"	"30.7"	"25.2"	"30.2"	"39.9"	"65.5"	"106.5"	"167.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96A35"	"39S ribosomal protein L24, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL24 PE=1 SV=1"	"5"	"1"	"2"	"1"	"216"	"24.9"	"9.29"	"359.91"	"2.79"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00467, Pf17136"	"79590"	"ENSG00000143314"	"MRPL24"	"D3DVC8; hsa:79590; Q53G65; Q53HT0; Q5SYZ9; Q5SZ00; Q5SZ02; Q96A35; Q96Q70; Q9H7G3"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"58.4"	"58.6"	"65.9"	"67.4"	"74.5"	"62.4"	"74.5"	"93.2"	"145.7"	"320.5"	"506.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60568"	"Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 OS=Homo sapiens OX=9606 GN=PLOD3 PE=1 SV=1"	"2"	"1"	"2"	"1"	"738"	"84.7"	"6.05"	"292.79"	"2.79"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"non-structural extracellular;extracellular matrix;other membranes;ER/Golgi"	"other molecular function"	"Pf03171"	"8985"	"ENSG00000106397"	"PLOD3"	"B2R6W6; hsa:8985; O60568; Q540C3"	"VEGFA-VEGFR2 signaling; IL-18 signaling pathway"	"Collagen biosynthesis and modifying enzymes"	"3"	"0"	"13.2"	"12.1"	"20.1"	"14.1"	"19.6"	"18.5"	"22.0"	"18.9"	"40.9"	"72.1"	"88.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63218"	"Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 OS=Homo sapiens OX=9606 GN=GNG5 PE=1 SV=3"	"13"	"1"	"2"	"1"	"68"	"7.3"	"9.85"	"390.75"	"2.79"	"1"	"1"	"signal transduction"	"plasma membrane;other membranes"	"other molecular function"	"Pf00631"	"2787"	"ENSG00000174021"	"GNG5"	"B2R5A0; hsa:2787; P30670; P63218; Q5VX54; Q61015"	"Myometrial relaxation and contraction pathways; G protein signaling pathways; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Ras signaling; Calcium regulation in cardiac cells"	"G alpha (12/13) signalling events; G alpha (q) signalling events; G alpha (i) signalling events; G alpha (z) signalling events; ADP signalling through P2Y purinoceptor 12; Extra-nuclear estrogen signaling; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production; Thrombin signalling through proteinase activated receptors (PARs); Activation of G protein gated Potassium channels; G-protein activation; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; G beta:gamma signalling through PI3Kgamma; Prostacyclin signalling through prostacyclin receptor; Adrenaline,noradrenaline inhibits insulin secretion; Ca2+ pathway; G beta:gamma signalling through PLC beta; ADP signalling through P2Y purinoceptor 1; Glucagon-type ligand receptors; Thromboxane signalling through TP receptor; Vasopressin regulates renal water homeostasis via Aquaporins; Presynaptic function of Kainate receptors; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; G beta:gamma signalling through BTK; G beta:gamma signalling through CDC42; Inhibition  of voltage gated Ca2+ channels via Gbeta/gamma subunits; Glucagon signaling in metabolic regulation"	"35"	"0"	"100.4"	"94.1"	"88.8"	"95.3"	"112.6"	"83.2"	"121.2"	"163.4"	"535.6"	"1463.7"	"1981.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TDJ6"	"DmX-like protein 2 OS=Homo sapiens OX=9606 GN=DMXL2 PE=1 SV=2"	"0"	"1"	"1"	"1"	"3036"	"339.4"	"6.38"	""	"2.79"	""	"1"	"other biological processes"	"other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf00400, Pf12234"	"23312"	"ENSG00000104093"	"DMXL2"	"B2RTR3; B7ZMH3; F5GWF1; hsa:23312; O94938; Q8TDJ6"	""	""	"0"	"0"	"86.1"	"15.6"	"151.0"	"92.7"	"117.8"	"117.8"	"102.3"	"69.8"	"155.9"	"216.6"	"360.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IWA4"	"Mitofusin-1 OS=Homo sapiens OX=9606 GN=MFN1 PE=1 SV=3"	"1"	"1"	"1"	"1"	"741"	"84.1"	"6.33"	""	"2.79"	""	"1"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf00350, Pf04799"	"55669"	"ENSG00000171109"	"MFN1"	"A0A0C4DFN1; B2RAR1; D3DNR6; hsa:55669; O15323; O60639; Q8IWA4; Q9BZB5; Q9NWQ2"	""	"Factors involved in megakaryocyte development and platelet production; PINK1-PRKN Mediated Mitophagy; RHOT2 GTPase cycle"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5J5"	"Pleckstrin homology-like domain family A member 3 OS=Homo sapiens OX=9606 GN=PHLDA3 PE=1 SV=1"	"6"	"1"	"2"	"1"	"127"	"13.9"	"9.67"	"306.79"	"2.78"	"1"	"1"	"stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"other molecular function"	""	"23612"	"ENSG00000174307"	"PHLDA3"	"B2R5A4; hsa:23612; Q53HD6; Q8NBW9; Q9Y5J5"	""	""	"0"	"0"	"56.2"	"64.1"	"72.0"	"66.5"	"96.6"	"83.6"	"131.9"	"210.7"	"329.9"	"479.6"	"532.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P18031"	"Tyrosine-protein phosphatase non-receptor type 1 OS=Homo sapiens OX=9606 GN=PTPN1 PE=1 SV=1"	"3"	"1"	"1"	"1"	"435"	"49.9"	"6.27"	""	"2.78"	""	"1"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"other membranes;cytosol;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00102"	"5770"	"ENSG00000196396"	"PTPN1"	"hsa:5770; P18031; Q5TGD8; Q9BQV9; Q9NQQ4"	"Leptin signaling pathway; Prolactin signaling pathway; Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4); VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Insulin signaling"	"Insulin receptor recycling; Growth hormone receptor signaling; Regulation of IFNG signaling; Regulation of IFNA/IFNB signaling; Negative regulation of MET activity; Integrin signaling; MECP2 regulates neuronal receptors and channels; PTK6 Down-Regulation"	"14"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"10.2"	"74.4"	"114.6"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A6NKF1"	"SAC3 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SAC3D1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"404"	"43.5"	"8.69"	"323.48"	"2.78"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;nucleus;other cell component"	""	"Pf03399"	""	""	"SAC3D1"	"A6NKF1; A8MX08; Q99773"	""	""	"0"	"0"	"28.6"	"23.3"	"26.9"	"22.8"	"17.2"	"19.0"	"23.6"	"54.1"	"74.5"	"190.8"	"281.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2G9"	"Protein strawberry notch homolog 2 OS=Homo sapiens OX=9606 GN=SBNO2 PE=2 SV=3"	"1"	"1"	"1"	"1"	"1366"	"150.2"	"6.52"	""	"2.78"	""	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf13871, Pf13872"	"22904"	"ENSG00000064932; ENSG00000278788"	"SBNO2"	"A8K8P2; B3KWJ1; hsa:22904; O75257; Q3KQX0; Q8TEM0; Q9Y2G9"	""	""	"0"	"0"	"71.0"	"62.1"	"102.4"	"77.9"	"83.1"	"81.1"	"86.5"	"70.0"	"113.4"	"166.7"	"241.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01433"	"AMP deaminase 2 OS=Homo sapiens OX=9606 GN=AMPD2 PE=1 SV=2"	"1"	"1"	"2"	"1"	"879"	"100.6"	"6.93"	"325.36"	"2.78"	"1"	"1"	"other metabolic processes;other biological processes"	"cytosol"	"other molecular function"	"Pf19326"	"271"	"ENSG00000116337"	"AMPD2"	"B4DK50; B4DZI5; E9PNG0; hsa:271; Q01433; Q14856; Q14857; Q16686; Q16687; Q16688; Q16729; Q5T693; Q5T695; Q96IA1; Q9UDX8; Q9UDX9; Q9UMU4"	""	"Purine salvage"	"1"	"0"	"52.5"	"56.1"	"69.6"	"59.0"	"59.0"	"53.2"	"61.8"	"94.7"	"152.6"	"268.3"	"424.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P26885"	"Peptidyl-prolyl cis-trans isomerase FKBP2 OS=Homo sapiens OX=9606 GN=FKBP2 PE=1 SV=2"	"13"	"2"	"3"	"2"	"142"	"15.6"	"9.13"	"645.34"	"2.78"	"2"	"1"	"protein metabolism;other metabolic processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf00254"	"2286"	"ENSG00000173486"	"FKBP2"	"hsa:2286; P26885; Q5BJH9; Q9BTS7"	"Complement system"	""	"1"	"0"	"110.3"	"110.3"	"109.3"	"102.0"	"109.4"	"110.7"	"148.4"	"183.9"	"780.5"	"2051.1"	"2241.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5HYJ3"	"Protein FAM76B OS=Homo sapiens OX=9606 GN=FAM76B PE=1 SV=3"	"3"	"1"	"1"	"1"	"339"	"38.7"	"9.25"	""	"2.78"	""	"1"	""	"nucleus"	""	"Pf16046"	"143684"	"ENSG00000077458"	"FAM76B"	"B2R9C2; hsa:143684; Q5HYJ3; Q6PIU3; Q8TC53"	""	""	"0"	"0"	"44.5"	"43.8"	"42.1"	"50.6"	"54.6"	"44.2"	"61.7"	"79.8"	"133.7"	"165.1"	"182.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04114"	"Apolipoprotein B-100 OS=Homo sapiens OX=9606 GN=APOB PE=1 SV=2"	"0"	"1"	"2"	"1"	"4563"	"515.3"	"7.05"	"327.61"	"2.77"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;transporter activity;other molecular function"	"Pf01347, Pf06448, Pf09172, Pf12491"	"338"	"ENSG00000084674"	"APOB"	"hsa:338; O00502; P04114; P78479; P78480; P78481; Q13779; Q13785; Q13786; Q13787; Q13788; Q4ZG63; Q53QC8; Q7Z600; Q9UMN0"	"Selenium micronutrient network; Vitamin B12 metabolism; Folate metabolism; Statin inhibition of cholesterol production; Male infertility; Perturbations to host-cell autophagy, induced by SARS-CoV-2 proteins; Familial hyperlipidemia type 2; Cholesterol metabolism; Female steroid hormones in cardiomyocyte energy metabolism; Fatty Acids and Lipoproteins Transport in Hepatocytes; Enterocyte cholesterol metabolism"	"Cell surface interactions at the vascular wall; Scavenging by Class B Receptors; Regulation of TLR by endogenous ligand; Heme signaling; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Retinoid metabolism and transport; Cargo recognition for clathrin-mediated endocytosis; LDL clearance; Chylomicron clearance; Scavenging by Class A Receptors; Chylomicron assembly; Chylomicron remodeling; VLDL assembly; VLDL clearance; Scavenging by Class F Receptors; Scavenging by Class H Receptors; Platelet sensitization by LDL; LDL remodeling"	"31"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"2.4"	"6.1"	"13.5"	"35.0"	"63.2"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95453"	"Poly(A)-specific ribonuclease PARN OS=Homo sapiens OX=9606 GN=PARN PE=1 SV=1"	"2"	"1"	"1"	"1"	"639"	"73.4"	"6.20"	""	"2.77"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04857, Pf08675"	"5073"	"ENSG00000140694; ENSG00000274829"	"PARN"	"B2RCB3; B4DDG8; B4DSB0; B4DWR4; B4E1H6; hsa:5073; O95453"	"Lung fibrosis"	"Deadenylation of mRNA; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA"	"4"	"0"	"27.5"	"20.2"	"38.5"	"24.3"	"26.4"	"23.7"	"41.1"	"62.7"	"194.7"	"416.1"	"616.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75446"	"Histone deacetylase complex subunit SAP30 OS=Homo sapiens OX=9606 GN=SAP30 PE=1 SV=1"	"5"	"1"	"2"	"1"	"220"	"23.3"	"9.17"	"271.90"	"2.77"	"1"	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf13866, Pf13867"	"8819"	"ENSG00000164105"	"SAP30"	"D3DP38; hsa:8819; O75446"	"Retinoblastoma gene in cancer; Notch signaling pathway"	"Potential therapeutics for SARS; HDACs deacetylate histones; NoRC negatively regulates rRNA expression"	"5"	"0"	"4.5"	"6.8"	"2.4"	"4.6"	"0.0"	"4.0"	"9.6"	"15.4"	"32.7"	"90.3"	"152.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P16383"	"GC-rich sequence DNA-binding factor 2 OS=Homo sapiens OX=9606 GN=GCFC2 PE=1 SV=2"	"1"	"1"	"2"	"1"	"781"	"89.3"	"5.99"	"291.52"	"2.77"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity"	"Pf07842"	"6936"	"ENSG00000005436"	"GCFC2"	"A4UHQ8; A4UHQ9; hsa:6936; O95032; P16383; Q53TY0; Q6P2F2"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"49.5"	"60.1"	"60.4"	"48.8"	"53.2"	"58.4"	"71.7"	"85.1"	"112.7"	"224.1"	"373.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q93050"	"V-type proton ATPase 116 kDa subunit a isoform 1 OS=Homo sapiens OX=9606 GN=ATP6V0A1 PE=1 SV=3"	"1"	"1"	"2"	"1"	"837"	"96.4"	"6.43"	"266.93"	"2.76"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf01496"	"535"	"ENSG00000033627"	"ATP6V0A1"	"B7Z3B7; hsa:535; Q8N5G7; Q93050; Q9NSX0"	""	"Neutrophil degranulation; ROS and RNS production in phagocytes; Insulin receptor recycling; Transferrin endocytosis and recycling; Ion channel transport"	"5"	"0"	"2.5"	"5.4"	"5.8"	"5.8"	"5.5"	"4.1"	"5.7"	"13.5"	"27.8"	"67.4"	"79.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14644"	"Ras GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=RASA3 PE=1 SV=3"	"1"	"1"	"2"	"1"	"834"	"95.6"	"7.15"	"369.58"	"2.76"	"1"	"1"	"transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol"	"transporter activity;enzyme regulator activity;other molecular function"	"Pf00168, Pf00169, Pf00616, Pf00779"	"22821"	"ENSG00000185989; ENSG00000280477"	"RASA3"	"A6NL15; F8W6X8; hsa:22821; Q14644; Q8IUY2"	"MAPK cascade; Ras signaling; IL-18 signaling pathway"	"Regulation of RAS by GAPs"	"4"	"0"	"36.9"	"43.9"	"41.2"	"38.5"	"48.3"	"43.4"	"71.1"	"135.4"	"298.8"	"313.3"	"293.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBB9"	"Tuftelin-interacting protein 11 OS=Homo sapiens OX=9606 GN=TFIP11 PE=1 SV=1"	"1"	"1"	"1"	"1"	"837"	"96.8"	"5.67"	""	"2.76"	""	"1"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"extracellular matrix;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01585, Pf07842, Pf12457"	"24144"	"ENSG00000100109"	"TFIP11"	"hsa:24144; O95908; Q20WL0; Q5H8V8; Q9UBB9; Q9UGV7; Q9Y2Q8"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"35.3"	"39.9"	"57.3"	"43.4"	"46.7"	"53.6"	"59.2"	"77.3"	"153.4"	"253.4"	"396.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UPN6"	"SR-related and CTD-associated factor 8 OS=Homo sapiens OX=9606 GN=SCAF8 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1271"	"140.4"	"8.29"	"284.09"	"2.75"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf04818"	"22828"	"ENSG00000213079"	"SCAF8"	"B7Z888; hsa:22828; Q5TBU6; Q6NSK3; Q9BQN8; Q9BX43; Q9UPN6"	""	""	"0"	"0"	"76.0"	"71.2"	"87.6"	"73.6"	"90.8"	"73.9"	"100.1"	"144.6"	"233.3"	"405.0"	"515.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5UCC4"	"ER membrane protein complex subunit 10 OS=Homo sapiens OX=9606 GN=EMC10 PE=1 SV=1"	"7"	"1"	"2"	"1"	"262"	"27.3"	"6.13"	"240.81"	"2.75"	"1"	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"non-structural extracellular;other membranes;ER/Golgi"	""	""	"284361"	"ENSG00000161671"	"EMC10"	"hsa:284361; Q5UCC4; Q5UCC6; Q69YT5; Q6UWP3; Q86YL4; Q8N541"	"22q11.2 copy number variation syndrome"	""	"1"	"0"	"60.7"	"48.1"	"56.8"	"43.4"	"58.2"	"55.4"	"63.5"	"87.3"	"129.9"	"260.2"	"380.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UGU0"	"Transcription factor 20 OS=Homo sapiens OX=9606 GN=TCF20 PE=1 SV=3"	"0"	"1"	"2"	"1"	"1960"	"211.6"	"9.04"	"344.80"	"2.75"	"1"	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf13771"	"6942"	"ENSG00000100207; ENSG00000262024; ENSG00000276461; ENSG00000280467; ENSG00000281897; ENSG00000282892; ENSG00000283026; ENSG00000283681"	"TCF20"	"A9JX12; hsa:6942; O14528; Q13078; Q4V353; Q9H4M0; Q9UGU0"	"Matrix metalloproteinases"	""	"1"	"0"	"103.1"	"83.9"	"108.8"	"82.9"	"91.3"	"109.6"	"114.4"	"115.4"	"156.2"	"255.7"	"315.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H3Q1"	"Cdc42 effector protein 4 OS=Homo sapiens OX=9606 GN=CDC42EP4 PE=1 SV=1"	"9"	"2"	"3"	"2"	"356"	"38.0"	"5.19"	"1095.73"	"2.74"	"2"	"1"	"cell organization and biogenesis;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00786, Pf14957"	"23580"	"ENSG00000179604"	"CDC42EP4"	"B3KUS7; hsa:23580; O95828; Q96FT3; Q9H3Q1"	""	"CDC42 GTPase cycle; RAC1 GTPase cycle; RAC2 GTPase cycle; RHOQ GTPase cycle"	"4"	"0"	"86.4"	"65.4"	"90.7"	"94.5"	"86.5"	"90.2"	"97.0"	"110.4"	"194.1"	"251.3"	"285.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46937"	"Transcriptional coactivator YAP1 OS=Homo sapiens OX=9606 GN=YAP1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"504"	"54.4"	"5.17"	"329.12"	"2.74"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00397"	"10413"	"ENSG00000137693"	"YAP1"	"B4DTY1; B7ZA01; E3WEB5; E3WEB6; E9PRV2; F5H202; hsa:10413; K0KQ18; K0KYZ8; K0L195; K0L1G3; P46937; Q7Z574; Q8IUY9"	"Mesodermal commitment pathway; Mesodermal commitment pathway; RAC1/PAK1/p38/MMP2 pathway; miR-509-3p alteration of YAP1/ECM axis; Ciliary landscape; Leukocyte-intrinsic Hippo pathway functions; Netrin-UNC5B signaling pathway; Galanin receptor pathway; Pleural mesothelioma"	"Signaling by Hippo; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Formation of axial mesoderm; Nuclear signaling by ERBB4; RUNX2 regulates osteoblast differentiation; YAP1- and WWTR1 (TAZ)-stimulated gene expression; EGR2 and SOX10-mediated initiation of Schwann cell myelination; RUNX3 regulates YAP1-mediated transcription"	"17"	"0"	"51.5"	"47.1"	"64.2"	"60.0"	"74.7"	"65.5"	"63.7"	"66.9"	"119.4"	"217.3"	"261.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IWJ2"	"GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4"	"1"	"1"	"2"	"1"	"1684"	"195.8"	"5.14"	"267.23"	"2.74"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"cytosol;ER/Golgi;nucleus"	"other molecular function"	"Pf01465, Pf16704"	"9648"	"ENSG00000135968"	"GCC2"	"A6H8X8; hsa:9648; O15045; Q4ZG46; Q8IWJ2; Q8TDH3; Q9H2G8"	"Deregulation of Rab and Rab effector genes in bladder cancer"	"Signaling by ALK fusions and activated point mutants; Retrograde transport at the Trans-Golgi-Network"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43674"	"NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFB5 PE=1 SV=1"	"6"	"1"	"2"	"1"	"189"	"21.7"	"9.63"	"291.95"	"2.74"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion;nucleus"	"transporter activity"	"Pf09781"	"4711"	"ENSG00000136521"	"NDUFB5"	"hsa:4711; O43674; Q561V6"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"7.4"	"5.0"	"7.4"	"4.1"	"6.9"	"9.4"	"9.9"	"11.7"	"46.0"	"95.1"	"138.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WXW3"	"Progesterone-induced-blocking factor 1 OS=Homo sapiens OX=9606 GN=PIBF1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"757"	"89.8"	"6.02"	"242.71"	"2.74"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding"	""	"10464"	"ENSG00000083535"	"PIBF1"	"hsa:10464; O95664; Q6U9V2; Q6UG50; Q86V07; Q8WXW3; Q96SF4"	"Genes related to primary cilium development (based on CRISPR); Joubert syndrome; Ciliopathies"	""	"3"	"0"	"7.9"	"9.3"	"11.3"	"10.3"	"14.2"	"11.8"	"18.3"	"25.7"	"114.3"	"105.5"	"126.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H9T3"	"Elongator complex protein 3 OS=Homo sapiens OX=9606 GN=ELP3 PE=1 SV=2"	"2"	"1"	"2"	"1"	"547"	"62.2"	"8.88"	"363.84"	"2.74"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00583, Pf04055, Pf16199"	"55140"	"ENSG00000134014"	"ELP3"	"B4DE19; B4DIG1; E2QRI5; hsa:55140; Q53G84; Q6AWB0; Q9BVF7; Q9H9T3; Q9NVZ1"	"Ethanol effects on histone modifications"	"HATs acetylate histones"	"2"	"0"	"15.7"	"16.1"	"15.7"	"12.5"	"17.6"	"21.9"	"19.3"	"22.9"	"49.7"	"167.8"	"345.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UEG4"	"Zinc finger protein 629 OS=Homo sapiens OX=9606 GN=ZNF629 PE=1 SV=2"	"1"	"1"	"2"	"1"	"869"	"96.6"	"7.93"	"244.83"	"2.74"	"1"	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00096"	"23361"	"ENSG00000102870"	"ZNF629"	"hsa:23361; Q15938; Q9UEG4"	""	""	"0"	"0"	"10.5"	"17.2"	"14.1"	"9.5"	"12.0"	"13.5"	"13.2"	"18.5"	"20.3"	"29.8"	"34.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3D7"	"Mitochondrial import inner membrane translocase subunit TIM16 OS=Homo sapiens OX=9606 GN=PAM16 PE=1 SV=2"	"9"	"1"	"2"	"1"	"125"	"13.8"	"9.70"	"260.68"	"2.74"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion;other cell component"	""	"Pf03656"	"51025"	"ENSG00000217930; ENSG00000282228"	"PAM16"	"hsa:51025; Q6I9Z3; Q9H5X3; Q9Y3D7"	""	"Mitochondrial protein import"	"1"	"0"	"23.6"	"20.7"	"18.5"	"20.7"	"22.3"	"21.2"	"25.4"	"35.1"	"47.7"	"90.8"	"118.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14699"	"Raftlin OS=Homo sapiens OX=9606 GN=RFTN1 PE=1 SV=4"	"3"	"1"	"2"	"1"	"578"	"63.1"	"5.67"	"318.30"	"2.74"	"1"	"1"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity"	"Pf15250"	"23180"	"ENSG00000131378"	"RFTN1"	"hsa:23180; Q0D2G0; Q14699; Q496Y2; Q4QQI7; Q5JB48; Q7Z7P2"	""	""	"0"	"0"	"7.4"	"3.9"	"6.4"	"7.6"	"5.6"	"7.8"	"3.1"	"10.1"	"47.8"	"55.7"	"74.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EA4"	"Protein Spindly OS=Homo sapiens OX=9606 GN=SPDL1 PE=1 SV=2"	"2"	"1"	"1"	"1"	"605"	"70.1"	"5.47"	""	"2.73"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	""	"54908"	"ENSG00000040275"	"SPDL1"	"B4E393; C9JS47; hsa:54908; Q8TEC8; Q96EA4; Q9HD44; Q9NX97"	""	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"6"	"0"	"12.0"	"12.3"	"12.9"	"7.8"	"12.5"	"10.3"	"12.7"	"16.0"	"61.8"	"127.7"	"216.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6PGP7"	"Tetratricopeptide repeat protein 37 OS=Homo sapiens OX=9606 GN=TTC37 PE=1 SV=1"	"1"	"1"	"1"	"1"	"1564"	"175.4"	"7.53"	""	"2.73"	""	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf13181, Pf13432"	"9652"	"ENSG00000198677"	"SKIC3"	"hsa:9652; O15077; Q6PGP7; Q6PJI3"	""	"mRNA decay by 3' to 5' exoribonuclease"	"1"	"0"	"0.0"	"2.1"	"0.0"	"0.0"	"0.0"	"0.0"	"3.1"	"2.5"	"17.1"	"90.7"	"174.2"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NSI6"	"Bromodomain and WD repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=BRWD1 PE=1 SV=4"	"1"	"1"	"2"	"1"	"2320"	"262.8"	"8.46"	"386.12"	"2.73"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"cytosol;nucleus"	""	"Pf00400, Pf00439"	"54014"	"ENSG00000185658"	"BRWD1"	"C9JK25; hsa:54014; O43721; Q5R2V0; Q5R2V1; Q6P2D1; Q8TCV3; Q96QG9; Q96QH0; Q9NSI6; Q9NUK1"	""	"Interleukin-7 signaling; Chromatin modifying enzymes"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"P06400"	"Retinoblastoma-associated protein OS=Homo sapiens OX=9606 GN=RB1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"928"	"106.1"	"7.94"	"273.34"	"2.72"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01857, Pf01858, Pf08934, Pf11934"	"5925"	"ENSG00000139687"	"RB1"	"A8K5E3; hsa:5925; P06400; P78499; Q5VW46; Q8IZL4"	"Androgen receptor signaling pathway; miRNA regulation of DNA damage response; Cell cycle; Thyroid stimulating hormone (TSH) signaling pathway; Glioblastoma signaling pathways; Adipogenesis; Spinal cord injury; Retinoblastoma gene in cancer; Aryl hydrocarbon receptor pathway; Bladder cancer; Fas ligand pathway and stress induction of heat shock proteins; H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity; Tumor suppressor activity of SMARCB1; Non-small cell lung cancer; Breast cancer pathway; Pancreatic adenocarcinoma pathway; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; Ciliary landscape; G1 to S cell cycle control; Small cell lung cancer; Head and neck squamous cell carcinoma; Melanoma; Overlap between signal transduction pathways contributing to LMNA laminopathies; 7q11.23 copy number variation syndrome; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Glycolysis in senescence; Sphingolipid metabolism in senescence; Prostaglandin and leukotriene metabolism in senescence ; ID signaling pathway; TROP2 regulatory signaling; Prostaglandin and leukotriene metabolism in senescence ; DNA damage response"	"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Oncogene Induced Senescence; Cyclin D associated events in G1; Defective binding of RB1 mutants to E2F1,(E2F2, E2F3); Aberrant regulation of mitotic exit in cancer due to RB1 defects; RUNX2 regulates osteoblast differentiation; Condensation of Prophase Chromosomes; Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes; Cyclin A:Cdk2-associated events at S phase entry; Formation of Senescence-Associated Heterochromatin Foci (SAHF); Inhibition of replication initiation of damaged DNA by RB1/E2F1; Defective translocation of RB1 mutants to the nucleus; Replication of the SARS-CoV-1 genome; Replication of the SARS-CoV-2 genome"	"47"	"0"	"118.1"	"91.1"	"141.3"	"113.1"	"123.5"	"136.4"	"154.1"	"149.4"	"202.4"	"321.4"	"479.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96MX6"	"WD repeat-containing protein 92 OS=Homo sapiens OX=9606 GN=WDR92 PE=1 SV=1"	"3"	"1"	"1"	"1"	"357"	"39.7"	"8.09"	""	"2.72"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"other cell component"	"other molecular function"	"Pf00400"	"116143"	"ENSG00000243667"	"DNAAF10"	"hsa:116143; Q96CR6; Q96MX6"	""	""	"0"	"0"	"7.6"	"9.3"	"15.3"	"9.5"	"13.6"	"8.3"	"11.8"	"20.6"	"63.7"	"131.8"	"200.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14676"	"Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3"	"0"	"1"	"2"	"1"	"2089"	"226.5"	"5.47"	"261.22"	"2.72"	"1"	"1"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	""	"Pf00498, Pf16770"	"9656"	"ENSG00000137337; ENSG00000206481; ENSG00000224587; ENSG00000225589; ENSG00000228575; ENSG00000231135; ENSG00000234012; ENSG00000237095"	"MDC1"	"A2AB04; A2BF04; A2RRA8; A7YY86; B0S8A2; hsa:9656; Q0EFC2; Q14676; Q2L6H7; Q2TAZ4; Q5JP55; Q5JP56; Q5ST83; Q68CQ3; Q86Z06; Q96QC2"	"ATM signaling in development and disease ; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; NIPBL role in DNA damage - Cornelia de Lange syndrome"	"SUMOylation of DNA damage response and repair proteins; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; TP53 Regulates Transcription of DNA Repair Genes; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; Nonhomologous End-Joining (NHEJ)"	"9"	"0"	"55.3"	"39.4"	"64.0"	"51.4"	"56.7"	"52.8"	"58.2"	"77.2"	"166.4"	"199.5"	"239.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92830"	"Histone acetyltransferase KAT2A OS=Homo sapiens OX=9606 GN=KAT2A PE=1 SV=3"	"2"	"1"	"1"	"1"	"837"	"93.9"	"9.04"	""	"2.72"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00439, Pf00583, Pf06466"	"2648"	"ENSG00000108773"	"KAT2A"	"hsa:2648; Q8N1A2; Q92830; Q9UCW1"	"Notch signaling"	"Ub-specific processing proteases; B-WICH complex positively regulates rRNA expression; Pre-NOTCH Transcription and Translation; HATs acetylate histones; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; NOTCH1 Intracellular Domain Regulates Transcription; Formation of paraxial mesoderm; Formation of WDR5-containing histone-modifying complexes; RNA Polymerase I Transcription Initiation; Cardiogenesis; Notch-HLH transcription pathway; NOTCH3 Intracellular Domain Regulates Transcription; Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells; NOTCH4 Intracellular Domain Regulates Transcription; RUNX3 regulates NOTCH signaling"	"17"	"0"	"303.1"	"97.2"	"520.6"	"364.0"	"389.7"	"372.5"	"343.1"	"268.6"	"357.1"	"451.1"	"733.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P54098"	"DNA polymerase subunit gamma-1 OS=Homo sapiens OX=9606 GN=POLG PE=1 SV=1"	"2"	"1"	"2"	"1"	"1239"	"139.5"	"6.90"	"351.31"	"2.72"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response"	"mitochondrion;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00476, Pf18136"	"5428"	"ENSG00000140521"	"POLG"	"hsa:5428; P54098; Q8NFM2; Q92515"	"Male infertility; Primary ovarian insufficiency"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96IJ6"	"Mannose-1-phosphate guanyltransferase alpha OS=Homo sapiens OX=9606 GN=GMPPA PE=1 SV=1"	"3"	"1"	"2"	"1"	"420"	"46.3"	"7.21"	"355.82"	"2.71"	"1"	"1"	"other metabolic processes"	"other cell component"	"other molecular function"	"Pf00483"	"29926"	"ENSG00000144591"	"GMPPA"	"A6NJ74; A8K3Q6; B3KMT4; hsa:29926; Q53GI0; Q96IJ6; Q9NWC3; Q9Y5P5"	"N-glycan biosynthesis"	"Synthesis of GDP-mannose"	"2"	"0"	"17.6"	"16.6"	"21.0"	"19.6"	"19.4"	"12.9"	"15.8"	"27.8"	"52.8"	"149.6"	"206.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NYZ3"	"G2 and S phase-expressed protein 1 OS=Homo sapiens OX=9606 GN=GTSE1 PE=1 SV=3"	"3"	"1"	"2"	"1"	"720"	"76.6"	"9.39"	"286.46"	"2.71"	"1"	"1"	"cell cycle OR cell proliferation;stress response;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus"	"cytoskeletal activity"	"Pf15259"	"51512"	"ENSG00000075218"	"GTSE1"	"B0QYM3; hsa:51512; Q20WK2; Q53GX5; Q5R3I6; Q6DHX4; Q9BRE0; Q9NYZ3; Q9UGZ9; Q9Y557"	""	"G2/M Checkpoints; The role of GTSE1 in G2/M progression after G2 checkpoint"	"2"	"0"	"15.6"	"13.7"	"18.4"	"18.7"	"21.9"	"14.7"	"23.8"	"15.3"	"32.7"	"47.0"	"54.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14191"	"Werner syndrome ATP-dependent helicase OS=Homo sapiens OX=9606 GN=WRN PE=1 SV=2"	"1"	"1"	"1"	"1"	"1432"	"162.4"	"6.34"	""	"2.71"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf00570, Pf01612, Pf09382, Pf14493, Pf16124"	"7486"	"ENSG00000165392"	"WRN"	"A1KYY9; hsa:7486; Q14191"	"Non-homologous end joining; DNA repair pathways, full network; Progeria-associated lipodystrophy; Primary ovarian insufficiency"	"Resolution of D-loop Structures through Holliday Junction Intermediates; Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; SUMOylation of DNA damage response and repair proteins; Removal of the Flap Intermediate from the C-strand"	"21"	"0"	"3.4"	"3.7"	"4.5"	"4.9"	"4.4"	"3.6"	"8.7"	"12.8"	"13.6"	"32.2"	"45.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96QT6"	"PHD finger protein 12 OS=Homo sapiens OX=9606 GN=PHF12 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1004"	"109.6"	"7.74"	"297.65"	"2.71"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00628, Pf16737"	"57649"	"ENSG00000109118"	"PHF12"	"hsa:57649; Q0VAI5; Q2TAK2; Q6ZML2; Q96QT6; Q9BV34; Q9H7U9; Q9P205"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95825"	"Quinone oxidoreductase-like protein 1 OS=Homo sapiens OX=9606 GN=CRYZL1 PE=1 SV=2"	"3"	"1"	"2"	"1"	"349"	"38.7"	"5.78"	"310.11"	"2.70"	"1"	"1"	"other metabolic processes"	""	"other molecular function"	""	"9946"	"ENSG00000205758"	"CRYZL1"	"B2RDX1; B3KQ77; hsa:9946; O95825; Q96DY0; Q9NVY7"	""	""	"0"	"0"	"3.2"	"2.7"	"3.8"	"2.2"	"3.1"	"3.9"	"3.6"	"7.4"	"27.4"	"43.9"	"58.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99798"	"Aconitate hydratase, mitochondrial OS=Homo sapiens OX=9606 GN=ACO2 PE=1 SV=2"	"1"	"1"	"1"	"1"	"780"	"85.4"	"7.61"	""	"2.70"	""	"1"	"other metabolic processes;stress response;developmental processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf00330, Pf00694"	"50"	"ENSG00000100412"	"ACO2"	"hsa:50; O75809; Q5JZ41; Q6FHX0; Q8TAQ6; Q99798"	"Amino acid metabolism; Metabolic reprogramming in colon cancer; Fluoroacetic acid toxicity; TCA cycle (aka Krebs or citric acid cycle)"	"Citric acid cycle (TCA cycle); Mitochondrial protein import"	"6"	"0"	"5.4"	"10.4"	"12.9"	"10.7"	"9.2"	"8.2"	"11.4"	"21.5"	"48.6"	"143.1"	"267.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BUK6"	"Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1"	"2"	"1"	"2"	"1"	"570"	"61.8"	"6.11"	"263.45"	"2.70"	"1"	"1"	"cell organization and biogenesis"	"other membranes;cytosol;mitochondrion;other cell component"	""	"Pf10644, Pf14881"	"55154"	"ENSG00000125459"	"MSTO1"	"hsa:55154; Q53GR8; Q5CZ69; Q5T717; Q68CT6; Q7LBZ8; Q7Z3M7; Q7Z558; Q8TE05; Q9BUK6; Q9NQX2; Q9NVU4"	""	""	"0"	"0"	"6.4"	"10.6"	"8.5"	"10.2"	"11.7"	"9.9"	"12.9"	"26.3"	"32.7"	"47.2"	"69.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13111"	"Chromatin assembly factor 1 subunit A OS=Homo sapiens OX=9606 GN=CHAF1A PE=1 SV=3"	"2"	"1"	"2"	"1"	"956"	"106.8"	"5.94"	"409.11"	"2.70"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf11600, Pf12253, Pf15539, Pf15557"	"10036"	"ENSG00000167670"	"CHAF1A"	"hsa:10036; Q13111; Q6NXG5; Q7Z7K3; Q9UJY8"	"Nanoparticle triggered autophagic cell death"	""	"1"	"0"	"25.7"	"19.8"	"18.0"	"16.9"	"22.3"	"23.5"	"22.9"	"28.9"	"42.2"	"53.9"	"69.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14669"	"E3 ubiquitin-protein ligase TRIP12 OS=Homo sapiens OX=9606 GN=TRIP12 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1992"	"220.3"	"8.48"	"298.17"	"2.70"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00632"	"9320"	"ENSG00000153827"	"TRIP12"	"D4HL82; hsa:9320; Q14669; Q14CA3; Q14CF1; Q15644; Q53R87; Q53TE7"	""	"Antigen processing: Ubiquitination & Proteasome degradation"	"1"	"0"	"39.2"	"33.9"	"42.8"	"37.9"	"39.7"	"46.3"	"50.2"	"57.0"	"81.1"	"194.0"	"253.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96PZ0"	"Pseudouridylate synthase 7 homolog OS=Homo sapiens OX=9606 GN=PUS7 PE=1 SV=2"	"2"	"1"	"2"	"1"	"661"	"75.0"	"6.37"	"317.11"	"2.70"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf01142"	"54517"	"ENSG00000091127"	"PUS7"	"hsa:54517; Q75MG4; Q96PZ0; Q9NX19"	""	"tRNA modification in the nucleus and cytosol"	"1"	"0"	"7.5"	"6.3"	"14.0"	"6.7"	"9.2"	"11.5"	"17.4"	"16.5"	"33.1"	"56.3"	"96.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14578"	"Citron Rho-interacting kinase OS=Homo sapiens OX=9606 GN=CIT PE=1 SV=2"	"1"	"1"	"2"	"1"	"2027"	"231.3"	"6.57"	"313.46"	"2.69"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069, Pf00169, Pf00780"	"11113"	"ENSG00000122966"	"CIT"	"hsa:11113; O14578; Q2M5E1; Q6XUH8; Q86UQ9; Q9UPZ7"	"Pleural mesothelioma; G13 signaling pathway"	"RHOC GTPase cycle; RHOA GTPase cycle; RAC1 GTPase cycle; RHOB GTPase cycle; RHO GTPases activate CIT"	"7"	"0"	"9.1"	"9.8"	"9.3"	"10.7"	"11.3"	"10.6"	"10.8"	"17.7"	"39.3"	"68.0"	"89.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13643"	"Four and a half LIM domains protein 3 OS=Homo sapiens OX=9606 GN=FHL3 PE=1 SV=4"	"4"	"1"	"2"	"1"	"280"	"31.2"	"6.20"	"256.62"	"2.69"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;nucleus"	"cytoskeletal activity;other molecular function"	"Pf00412"	"2275"	"ENSG00000183386"	"FHL3"	"D3DPT6; hsa:2275; Q13643; Q6I9T0; Q9BVA2"	""	""	"0"	"0"	"72.8"	"65.2"	"95.6"	"62.8"	"90.5"	"83.5"	"93.0"	"105.1"	"151.6"	"344.6"	"512.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NEY1"	"Neuron navigator 1 OS=Homo sapiens OX=9606 GN=NAV1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1877"	"202.3"	"8.07"	"284.99"	"2.69"	"1"	"1"	"cell organization and biogenesis;developmental processes"	"cytoskeleton;other cell component"	""	""	"89796"	"ENSG00000134369"	"NAV1"	"A8MS88; hsa:89796; Q5SVH1; Q5SVH2; Q5SVH3; Q5SVH7; Q5VUY9; Q8IVL2; Q8NEY1; Q96II1; Q9H7V9; Q9H9S9; Q9H9T5; Q9UGI1; Q9ULK7; Q9ULR9"	""	""	"0"	"0"	"9.2"	"10.8"	"7.0"	"14.1"	"7.5"	"12.3"	"11.7"	"14.2"	"21.1"	"31.7"	"46.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q06609"	"DNA repair protein RAD51 homolog 1 OS=Homo sapiens OX=9606 GN=RAD51 PE=1 SV=1"	"4"	"1"	"2"	"1"	"339"	"36.9"	"5.60"	"312.67"	"2.69"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf08423, Pf14520"	"5888"	"ENSG00000051180"	"RAD51"	"B0FXP0; B2R8T6; hsa:5888; Q06609; Q6FHX9; Q6ZNA8; Q9BV60"	"miRNA regulation of DNA damage response; Homologous recombination; ATM signaling pathway; RAC1/PAK1/p38/MMP2 pathway; Ovarian infertility; Breast cancer pathway; Pancreatic adenocarcinoma pathway; DNA repair pathways, full network; Primary ovarian insufficiency; DNA damage response"	"Resolution of D-loop Structures through Holliday Junction Intermediates; Transcriptional Regulation by E2F6; Presynaptic phase of homologous DNA pairing and strand exchange; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; Meiotic recombination; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51"	"23"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q3SXY8"	"ADP-ribosylation factor-like protein 13B OS=Homo sapiens OX=9606 GN=ARL13B PE=1 SV=1"	"3"	"1"	"2"	"1"	"428"	"48.6"	"6.62"	"297.29"	"2.69"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00025"	"200894"	"ENSG00000169379"	"ARL13B"	"D3DN29; G3V1S8; hsa:200894; Q3SXY8; Q504W8; Q8TCL5"	"Genes related to primary cilium development (based on CRISPR); Joubert syndrome; Ciliopathies; Bardet-Biedl syndrome"	"Aggrephagy; RHOQ GTPase cycle; RHOJ GTPase cycle; Late endosomal microautophagy; ARL13B-mediated ciliary trafficking of INPP5E; Chaperone Mediated Autophagy"	"10"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NQ66"	"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 OS=Homo sapiens OX=9606 GN=PLCB1 PE=1 SV=1"	"1"	"1"	"1"	"1"	"1216"	"138.5"	"6.23"	""	"2.69"	""	"1"	"cell-cell signaling;cell cycle OR cell proliferation;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00387, Pf00388, Pf06631, Pf08703, Pf09279, Pf17787"	"23236"	"ENSG00000182621"	"PLCB1"	"D3DW12; D3DW13; hsa:23236; O60325; Q17RQ6; Q5TFF7; Q5TGC9; Q8IV93; Q9BQW2; Q9H4H2; Q9H8H5; Q9NQ65; Q9NQ66; Q9NQH9; Q9NTH4; Q9UJP6; Q9UM26"	"AMP-activated protein kinase signaling; Thyroid stimulating hormone (TSH) signaling pathway; Alzheimer's disease and miRNA effects; Endothelin pathways; S1P receptor signal transduction; Cell-type dependent selectivity of CCK2R signaling; Chemokine signaling pathway; GPR40 pathway; Wnt signaling; Non-genomic actions of 1,25 dihydroxyvitamin D3; Resistin as a regulator of inflammation; Hippo signaling regulation pathways; Fragile X syndrome; PKC-gamma calcium signaling pathway in ataxia; Kisspeptin/kisspeptin receptor system in the ovary; GPR143 in melanocytes and retinal pigment epithelium cells; Airway smooth muscle cell contraction; Neuroinflammation and glutamatergic signaling; Alzheimer's disease"	"Ca2+ pathway; G alpha (q) signalling events; G beta:gamma signalling through PLC beta; Presynaptic function of Kainate receptors; Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion; Synthesis of IP3 and IP4 in the cytosol; PLC beta mediated events; Acetylcholine regulates insulin secretion"	"27"	"0"	"11.2"	"10.0"	"16.7"	"14.7"	"11.2"	"12.8"	"14.0"	"15.5"	"54.2"	"77.2"	"84.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BWU0"	"Kanadaptin OS=Homo sapiens OX=9606 GN=SLC4A1AP PE=1 SV=1"	"1"	"1"	"2"	"1"	"796"	"88.8"	"5.19"	"279.60"	"2.69"	"1"	"1"	""	"plasma membrane;other membranes;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00498"	"22950"	"ENSG00000163798"	"SLC4A1AP"	"A6NJ39; hsa:22950; Q4KMT1; Q4KMX0; Q7Z5Q9; Q9BWU0; Q9NVN2"	""	""	"0"	"0"	"66.8"	"77.5"	"75.2"	"62.2"	"71.8"	"71.5"	"103.1"	"127.4"	"164.6"	"413.7"	"937.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75694"	"Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1"	"1"	"1"	"1"	"1"	"1391"	"155.1"	"6.16"	""	"2.69"	""	"1"	"cell-cell signaling;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;nucleus"	"other molecular function"	"Pf03177, Pf08801"	"9631"	"ENSG00000113569"	"NUP155"	"hsa:9631; O75694; Q9UBE9; Q9UFL5"	""	"ISG15 antiviral mechanism; HCMV Late Events; HCMV Early Events; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Postmitotic nuclear pore complex (NPC) reformation"	"29"	"0"	"66.6"	"70.4"	"71.5"	"58.2"	"82.2"	"67.7"	"93.9"	"112.1"	"182.4"	"248.3"	"299.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P45877"	"Peptidyl-prolyl cis-trans isomerase C OS=Homo sapiens OX=9606 GN=PPIC PE=1 SV=1"	"5"	"1"	"1"	"1"	"212"	"22.7"	"8.40"	""	"2.68"	""	"1"	"protein metabolism;other metabolic processes"	"other cell component"	"other molecular function"	"Pf00160"	"5480"	"ENSG00000168938"	"PPIC"	"A4LBB5; hsa:5480; P45877"	""	""	"0"	"0"	"27.9"	"28.4"	"32.3"	"30.6"	"35.6"	"35.6"	"40.7"	"50.8"	"92.4"	"180.6"	"226.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75165"	"DnaJ homolog subfamily C member 13 OS=Homo sapiens OX=9606 GN=DNAJC13 PE=1 SV=5"	"1"	"1"	"2"	"1"	"2243"	"254.3"	"6.74"	"334.77"	"2.68"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	""	"Pf00226, Pf14237, Pf19432"	"23317"	"ENSG00000138246"	"DNAJC13"	"hsa:23317; O75165; Q3L0T1; Q6PI82; Q6UJ77; Q6ZSW1; Q6ZUT5; Q86XG3; Q96DC1; Q9BWK9"	""	"Neutrophil degranulation"	"1"	"0"	"16.6"	"13.5"	"16.1"	"15.6"	"14.1"	"16.8"	"16.5"	"21.3"	"39.0"	"74.2"	"102.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NSA2"	"Potassium voltage-gated channel subfamily D member 1 OS=Homo sapiens OX=9606 GN=KCND1 PE=1 SV=2"	"4"	"1"	"1"	"1"	"647"	"71.3"	"8.44"	""	"2.67"	""	"1"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;other cell component"	"transporter activity;other molecular function"	"Pf00520, Pf02214, Pf11601, Pf11879"	"3750"	"ENSG00000102057"	"KCND1"	"A6NEF1; B2RCG0; hsa:3750; O75671; Q9NSA2"	""	"Voltage gated Potassium channels; Phase 1 - inactivation of fast Na+ channels"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H1E3"	"Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 OS=Homo sapiens OX=9606 GN=NUCKS1 PE=1 SV=1"	"4"	"1"	"2"	"1"	"243"	"27.3"	"5.08"	"283.01"	"2.67"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	""	"64710"	"ENSG00000069275"	"NUCKS1"	"hsa:64710; Q54AC0; Q5PXE7; Q9H1D6; Q9H1E3; Q9H723"	""	""	"0"	"0"	"48.3"	"53.9"	"45.6"	"43.7"	"49.1"	"44.0"	"53.8"	"70.3"	"139.8"	"238.4"	"292.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P48507"	"Glutamate--cysteine ligase regulatory subunit OS=Homo sapiens OX=9606 GN=GCLM PE=1 SV=1"	"5"	"1"	"2"	"1"	"274"	"30.7"	"6.02"	"347.54"	"2.66"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;stress response;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00248"	"2730"	"ENSG00000023909"	"GCLM"	"A8K334; D3DT45; hsa:2730; M5A959; P48507; Q6FHC1; Q9NPX9; Q9NU74"	"Glutathione metabolism; Trans-sulfuration pathway; Trans-sulfuration, one-carbon metabolism and related pathways; Nuclear receptors meta-pathway; NRF2 pathway; Transcriptional activation by NRF2 in response to phytochemicals; Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling; Amino acid metabolism; Ferroptosis; NRF2-ARE regulation; Antiviral and anti-inflammatory effects of Nrf2 on SARS-CoV-2 pathway"	"Glutathione synthesis and recycling; NFE2L2 regulating anti-oxidant/detoxification enzymes; Defective GCLC causes HAGGSD"	"14"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P53990"	"IST1 homolog OS=Homo sapiens OX=9606 GN=IST1 PE=1 SV=1"	"2"	"1"	"1"	"1"	"364"	"39.7"	"5.35"	""	"2.66"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf03398"	"9798"	"ENSG00000182149"	"IST1"	"A8KAH5; hsa:9798; J3QLU7; P53990; Q3SYM4; Q9BQ81; Q9BWN2"	""	"Neutrophil degranulation; Sealing of the nuclear envelope (NE) by ESCRT-III"	"2"	"0"	"41.7"	"47.0"	"41.9"	"36.3"	"36.4"	"35.6"	"44.9"	"59.7"	"265.4"	"1189.4"	"1582.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TC07"	"TBC1 domain family member 15 OS=Homo sapiens OX=9606 GN=TBC1D15 PE=1 SV=2"	"2"	"1"	"1"	"1"	"691"	"79.4"	"5.67"	""	"2.66"	""	"1"	"other biological processes"	"non-structural extracellular;other cell component"	"enzyme regulator activity"	"Pf00566, Pf12068"	"64786"	"ENSG00000121749"	"TBC1D15"	"B4DMT9; B9A6L6; hsa:64786; J3KNI9; Q8TC07; Q9HA83"	""	"TBC/RABGAPs"	"1"	"0"	"0.0"	"3.4"	"3.7"	"3.1"	"5.2"	"6.2"	"3.6"	"6.2"	"13.9"	"27.4"	"39.6"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6IQ23"	"Pleckstrin homology domain-containing family A member 7 OS=Homo sapiens OX=9606 GN=PLEKHA7 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1121"	"127.1"	"9.35"	"325.19"	"2.66"	"1"	"1"	"cell adhesion;cell organization and biogenesis"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00169"	"144100"	"ENSG00000166689"	"PLEKHA7"	"B4DK33; B4DWC3; hsa:144100; Q6IQ23; Q86VZ7"	""	""	"0"	"0"	"69.4"	"70.2"	"83.4"	"70.4"	"91.2"	"82.2"	"83.6"	"122.2"	"221.7"	"321.5"	"384.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19447"	"General transcription and DNA repair factor IIH helicase subunit XPB OS=Homo sapiens OX=9606 GN=ERCC3 PE=1 SV=1"	"2"	"1"	"1"	"1"	"782"	"89.2"	"7.23"	""	"2.66"	""	"1"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04851, Pf13625, Pf16203"	"2071"	"ENSG00000163161"	"ERCC3"	"hsa:2071; P19447; Q53QM0"	"Eukaryotic transcription initiation; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Dual Incision in GG-NER"	"33"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P27448"	"MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens OX=9606 GN=MARK3 PE=1 SV=5"	"2"	"1"	"2"	"1"	"753"	"84.4"	"9.57"	"418.48"	"2.66"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"cytoskeletal activity;kinase activity;other molecular function"	"Pf00069, Pf00627, Pf02149"	"4140"	"ENSG00000075413"	"MARK3"	"A0A0A0MQR8; A0A0A0MST9; A0A0A0MT23; hsa:4140; O60219; P27448; Q86TT8; Q8TB41; Q8WX83; Q96RG1; Q9UMY9; Q9UN34"	"Complement system in neuronal development and plasticity"	"Signaling by BRAF and RAF1 fusions; RAF activation; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Negative regulation of MAPK pathway; Signaling by high-kinase activity BRAF mutants"	"10"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96GD4"	"Aurora kinase B OS=Homo sapiens OX=9606 GN=AURKB PE=1 SV=3"	"3"	"1"	"2"	"1"	"344"	"39.3"	"9.29"	"241.12"	"2.66"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"9212"	"ENSG00000178999"	"AURKB"	"B4DNM4; C7G533; C7G534; C7G535; D3DTR4; hsa:9212; J9JID1; O14630; O60446; O95083; Q96DV5; Q96GD4; Q9UQ46"	"Microtubule cytoskeleton regulation; ATM signaling in development and disease"	"RHO GTPases Activate Formins; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; EML4 and NUDC in mitotic spindle formation; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Regulation of MECP2 expression and activity; SUMOylation of DNA replication proteins; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Regulation of TP53 Activity through Phosphorylation"	"12"	"0"	"43.4"	"28.3"	"67.3"	"57.7"	"57.9"	"65.0"	"66.6"	"52.2"	"99.9"	"149.9"	"211.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5T200"	"Zinc finger CCCH domain-containing protein 13 OS=Homo sapiens OX=9606 GN=ZC3H13 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1668"	"196.5"	"9.42"	"334.56"	"2.65"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00642"	"23091"	"ENSG00000123200"	"ZC3H13"	"A2A323; hsa:23091; O94936; Q5T1Z9; Q5T200; Q7Z7J3; Q8NDT6; Q9H0L6"	""	""	"0"	"0"	"63.9"	"40.2"	"77.6"	"45.7"	"66.5"	"65.4"	"71.4"	"82.4"	"160.7"	"248.3"	"383.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49902"	"Cytosolic purine 5'-nucleotidase OS=Homo sapiens OX=9606 GN=NT5C2 PE=1 SV=1"	"3"	"1"	"2"	"1"	"561"	"64.9"	"6.14"	"242.79"	"2.65"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf05761"	"22978"	"ENSG00000076685"	"NT5C2"	"B7Z382; D3DR91; hsa:22978; P49902; Q5JUV5"	""	"Purine catabolism; Ribavirin ADME; Abacavir metabolism"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EB6"	"NAD-dependent protein deacetylase sirtuin-1 OS=Homo sapiens OX=9606 GN=SIRT1 PE=1 SV=2"	"1"	"1"	"1"	"1"	"747"	"81.6"	"4.67"	""	"2.65"	""	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf02146"	"23411"	"ENSG00000096717"	"SIRT1"	"hsa:23411; Q2XNF6; Q5JVQ0; Q96EB6; Q9GZR9; Q9Y6F0"	"Androgen receptor signaling pathway; Energy metabolism; Sterol regulatory element-binding proteins (SREBP) signaling; SREBF and miR33 in cholesterol and lipid homeostasis; Melatonin metabolism and effects; NAD metabolism, sirtuins and aging; NAD+ metabolism; NAD+ biosynthetic pathways; Interactions between LOXL4 and oxidative stress pathway; Somatroph axis (GH) and its relationship to dietary restriction and aging; Caloric restriction and aging; CAMKK2 pathway; 3q29 copy number variation syndrome; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Inclusion body myositis; Prostaglandin and leukotriene metabolism in senescence ; DYRK1A involvement regarding cell proliferation in brain development; Primary ovarian insufficiency; Prostaglandin and leukotriene metabolism in senescence ; 10q11.21q11.23 copy number variation syndrome; TAR syndrome"	"SIRT1 negatively regulates rRNA expression; Regulation of HSF1-mediated heat shock response; Heme signaling; Circadian Clock; Regulation of FOXO transcriptional activity by acetylation"	"26"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43617"	"Trafficking protein particle complex subunit 3 OS=Homo sapiens OX=9606 GN=TRAPPC3 PE=1 SV=1"	"4"	"1"	"2"	"1"	"180"	"20.3"	"4.96"	"294.16"	"2.64"	"1"	"1"	"cell organization and biogenesis;transport"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf04051"	"27095"	"ENSG00000054116"	"TRAPPC3"	"A6NDN0; B2RDN2; D3DPS2; hsa:27095; O43617"	""	"RAB GEFs exchange GTP for GDP on RABs; COPII-mediated vesicle transport"	"2"	"0"	"41.7"	"40.5"	"43.8"	"37.3"	"44.1"	"43.9"	"60.5"	"98.1"	"191.7"	"540.0"	"867.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UHR4"	"Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 OS=Homo sapiens OX=9606 GN=BAIAP2L1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"511"	"56.8"	"8.68"	"385.34"	"2.64"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus"	"cytoskeletal activity;other molecular function"	"Pf08397, Pf14604"	"55971"	"ENSG00000006453"	"BAIAP2L1"	"A4D268; hsa:55971; Q75L21; Q75L22; Q96CV4; Q9H5F5; Q9UHR4; Q9Y2M8"	""	"RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOF GTPase cycle"	"4"	"0"	"192.3"	"85.3"	"190.0"	"161.1"	"216.1"	"200.1"	"220.0"	"222.9"	"285.8"	"200.7"	"199.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60825"	"6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2"	"2"	"1"	"2"	"1"	"505"	"58.4"	"8.38"	"325.36"	"2.64"	"1"	"1"	"other metabolic processes;other biological processes"	"cytosol;nucleus"	"kinase activity;other molecular function"	"Pf00300, Pf01591"	"5208"	"ENSG00000123836"	"PFKFB2"	"hsa:5208; O60824; O60825; Q5VVQ3; Q5VVQ4; Q9H3P1"	"Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Thyroid hormones production and peripheral downstream signaling effects"	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96B26"	"Exosome complex component RRP43 OS=Homo sapiens OX=9606 GN=EXOSC8 PE=1 SV=1"	"6"	"1"	"2"	"1"	"276"	"30.0"	"5.30"	"249.98"	"2.64"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01138, Pf03725"	"11340"	"ENSG00000120699"	"EXOSC8"	"hsa:11340; O43480; Q5TBA5; Q96B26"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	"6"	"0"	"18.1"	"15.9"	"22.7"	"18.9"	"20.4"	"28.2"	"23.4"	"29.2"	"70.6"	"160.9"	"239.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19838"	"Nuclear factor NF-kappa-B p105 subunit OS=Homo sapiens OX=9606 GN=NFKB1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"968"	"105.3"	"5.40"	"284.06"	"2.64"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"non-structural extracellular;cytosol;mitochondrion;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00023, Pf00531, Pf00554, Pf16179"	"4790"	"ENSG00000109320"	"NFKB1"	"A8K5Y5; B3KVE8; hsa:4790; P19838; Q68D84; Q86V43; Q8N4X7; Q9NZC0"	"Osteopontin signaling; Selenium micronutrient network; Vitamin B12 metabolism; MicroRNAs in cardiomyocyte hypertrophy; Transcription factors regulate miRNAs related to cardiac hypertrophy; Folate metabolism; IL-1 signaling pathway; RANKL/RANK signaling pathway; Leptin signaling pathway; TNF-related weak inducer of apoptosis (TWEAK) signaling pathway; Prolactin signaling pathway; Alzheimer's disease and miRNA effects; Neural crest differentiation; IL-17 signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; B cell receptor signaling pathway; TNF-alpha signaling pathway; AGE/RAGE pathway; Corticotropin-releasing hormone signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Quercetin and Nf-kB / AP-1 induced apoptosis; PDGF pathway; Apoptosis; T cell receptor and co-stimulatory signaling; Aryl hydrocarbon receptor pathway; Ebstein-Barr virus LMP1 signaling; Cardiac hypertrophic response; Apoptosis-related network due to altered Notch3 in ovarian cancer; IL1 and megakaryocytes in obesity; Myometrial relaxation and contraction pathways; Melatonin metabolism and effects; RAC1/PAK1/p38/MMP2 pathway; Initiation of transcription and translation elongation at the HIV-1 LTR; Photodynamic therapy-induced NF-kB survival signaling; NAD metabolism, sirtuins and aging; Hepatitis C and hepatocellular carcinoma; MAPK signaling pathway; Apoptosis modulation by HSP70; MAPK and NFkB signaling pathways inhibited by Yersinia YopJ; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; TLR4 signaling and tolerance; Toll-like receptor signaling related to MyD88; T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection; Novel intracellular components of RIG-I-like receptor pathway; MYD88 distinct input-output pathway; ATM signaling in development and disease ; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Oxidative damage response; IL-4 signaling pathway; Prion disease pathway; NO/cGMP/PKG mediated neuroprotection; Oxidative stress response; Fibrin complement receptor 3 signaling pathway; PI3K-Akt signaling pathway; Ebola virus infection in host; Ras signaling; Pancreatic adenocarcinoma pathway; miRNA role in immune response in sepsis; ncRNAs involved in STAT3 signaling in hepatocellular carcinoma; Non-genomic actions of 1,25 dihydroxyvitamin D3; Ciliary landscape; Nonalcoholic fatty liver disease; Supression of HMGB1 mediated inflammation by THBD; Altered glycosylation of MUC1 in tumor microenvironment; Resistin as a regulator of inflammation; Vitamin D in inflammatory diseases; Signal transduction through IL1R; Interactions between immune cells and microRNAs in tumor microenvironment; Canonical NF-kB pathway; Cancer immunotherapy by PD-1 blockade; Measles virus infection; Cytosolic DNA-sensing pathway; Small cell lung cancer; Gastrin signaling pathway; Hepatitis B infection; Head and neck squamous cell carcinoma; Aspirin and miRNAs; IL-18 signaling pathway; Autosomal recessive osteopetrosis pathways; FGF23 signaling in hypophosphatemic rickets and related disorders; TGF-beta receptor signaling in skeletal dysplasias; Kisspeptin/kisspeptin receptor system in the ovary; Activation of NLRP3 inflammasome by SARS-CoV-2; Host-pathogen interaction of human coronaviruses - interferon induction; 16p11.2 proximal deletion syndrome; STING pathway in Kawasaki-like disease and COVID-19; RAS and bradykinin pathways in COVID-19; Mitochondrial immune response to SARS-CoV-2; SARS-CoV-2 innate immunity evasion and cell-specific immune response; Modulators of TCR signaling and T cell activation; Neuroinflammation and glutamatergic signaling; Pleural mesothelioma; Prostaglandin signaling; Antiviral and anti-inflammatory effects of Nrf2 on SARS-CoV-2 pathway; Inclusion body myositis; Alzheimer's disease; Th17 cell differentiation pathway; Ulcerative colitis signaling; SARS-CoV-2 mitochondrial chronic oxidative stress and endothelial dysfunction; Modulation of PI3K-Akt-mTOR signaling by bioactive sphingolipids; Inflammatory bowel disease signaling; Genetic causes of porto-sinusoidal vascular disease; TROP2 regulatory signaling; Autophagy in pancreatic ductal adenocarcinoma; A network map of Macrophage-stimulating protein (MSP) signaling; Disturbed pathways in Duchenne Muscular Dystrophy; TAR syndrome; Role of hypoxia, angiogenesis, and FGF pathway in OA chondrocyte hypertrophy; 10q22q23 copy number variation; TGF-beta receptor signaling; Notch signaling pathway; T-cell receptor signaling pathway; Sudden infant death syndrome (SIDS) susceptibility pathways; Estrogen signaling pathway; Toll-like receptor signaling pathway"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Transcriptional regulation of white adipocyte differentiation; Activation of NF-kappaB in B cells; HCMV Early Events; Neutrophil degranulation; Senescence-Associated Secretory Phenotype (SASP); Transcriptional Regulation by VENTX; PKMTs methylate histone lysines; RIP-mediated NFkB activation via ZBP1; NF-kB is activated and signals survival; TAK1-dependent IKK and NF-kappa-B activation  ; IkBA variant leads to EDA-ID; MAP3K8 (TPL2)-dependent MAPK1/3 activation; TRAF6 mediated NF-kB activation; The NLRP3 inflammasome; Purinergic signaling in leishmaniasis infection; SARS-CoV-1 activates/modulates innate immune responses; CD209 (DC-SIGN) signaling; Interleukin-1 processing; CLEC7A/inflammasome pathway; Regulated proteolysis of p75NTR; DEx/H-box helicases activate type I IFN and inflammatory cytokines production"	"142"	"0"	"86.8"	"87.3"	"113.4"	"91.2"	"104.2"	"89.4"	"118.8"	"164.7"	"267.7"	"380.6"	"484.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3C4"	"EKC/KEOPS complex subunit TPRKB OS=Homo sapiens OX=9606 GN=TPRKB PE=1 SV=1"	"4"	"1"	"2"	"1"	"175"	"19.6"	"6.79"	"286.00"	"2.64"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf08617"	"51002"	"ENSG00000144034"	"TPRKB"	"D6W5H6; hsa:51002; Q8IWR6; Q8IWR7; Q9H3K4; Q9Y3C4"	""	"tRNA modification in the nucleus and cytosol"	"1"	"0"	"49.7"	"53.6"	"50.0"	"55.7"	"53.1"	"48.4"	"66.9"	"92.7"	"155.2"	"307.2"	"495.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15031"	"Plexin-B2 OS=Homo sapiens OX=9606 GN=PLXNB2 PE=1 SV=3"	"1"	"1"	"2"	"1"	"1838"	"205.0"	"6.24"	"317.96"	"2.63"	"1"	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf01403, Pf01437, Pf01833, Pf08337, Pf17960, Pf20170"	"23654"	"ENSG00000196576"	"PLXNB2"	"A6QRH0; hsa:23654; O15031; Q7KZU3; Q9BSU7"	"2q11.2 copy number variation syndrome"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9GZU8"	"PSME3-interacting protein OS=Homo sapiens OX=9606 GN=PSME3IP1 PE=1 SV=1"	"3"	"1"	"1"	"1"	"254"	"28.9"	"5.45"	""	"2.63"	""	"1"	"other biological processes"	"nucleus;other cell component"	""	"Pf10187"	"80011"	"ENSG00000172775"	"PSME3IP1"	"hsa:80011; Q9GZU8"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96DV4"	"39S ribosomal protein L38, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL38 PE=1 SV=2"	"2"	"1"	"2"	"1"	"380"	"44.6"	"7.53"	"308.88"	"2.63"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	""	"Pf01161"	"64978"	"ENSG00000204316"	"MRPL38"	"B3KN96; hsa:64978; Q96DV4; Q96Q66; Q9P0B9"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"51.3"	"52.4"	"65.2"	"56.7"	"48.9"	"40.7"	"77.3"	"77.6"	"83.5"	"228.6"	"414.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q07954"	"Prolow-density lipoprotein receptor-related protein 1 OS=Homo sapiens OX=9606 GN=LRP1 PE=1 SV=2"	"0"	"1"	"1"	"1"	"4544"	"504.3"	"5.39"	""	"2.63"	""	"1"	"other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00057, Pf00058, Pf07645, Pf12662, Pf14670, Pf16472"	"4035"	"ENSG00000123384"	"LRP1"	"hsa:4035; Q07954; Q2PP12; Q86SW0; Q8IVG8"	"Alzheimer's disease and miRNA effects; Regulation of Wnt / B-catenin signaling by small molecule compounds; Statin inhibition of cholesterol production; Familial  hyperlipidemia type 1; Familial hyperlipidemia type 3; Familial hyperlipidemia type 4; Familial hyperlipidemia type 5; Alzheimer's disease; Cholesterol metabolism"	"Retinoid metabolism and transport; Scavenging of heme from plasma"	"11"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NB49"	"Phospholipid-transporting ATPase IG OS=Homo sapiens OX=9606 GN=ATP11C PE=1 SV=3"	"1"	"1"	"1"	"1"	"1132"	"129.4"	"6.67"	""	"2.62"	""	"1"	"cell organization and biogenesis;transport"	"plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf00122, Pf13246, Pf16209, Pf16212"	"286410"	"ENSG00000101974"	"ATP11C"	"hsa:286410; Q5JT69; Q5JT70; Q5JT71; Q5JT72; Q5JT73; Q6ZND5; Q6ZU50; Q6ZUP7; Q70IJ9; Q70IK0; Q8NB49; Q8WX24"	"Complement system in neuronal development and plasticity"	"Ion transport by P-type ATPases"	"2"	"0"	"0.0"	"4.4"	"4.3"	"6.0"	"4.4"	"1.9"	"3.9"	"7.5"	"16.0"	"37.6"	"59.0"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49137"	"MAP kinase-activated protein kinase 2 OS=Homo sapiens OX=9606 GN=MAPKAPK2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"400"	"45.5"	"8.68"	"321.15"	"2.62"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"9261"	"ENSG00000162889"	"MAPKAPK2"	"hsa:9261; P49137; Q5SY30; Q5SY41; Q8IYD6"	"IL-1 signaling pathway; Microtubule cytoskeleton regulation; Interleukin-1 (IL-1) structural pathway; Fas ligand pathway and stress induction of heat shock proteins; MAPK signaling pathway; VEGFA-VEGFR2 signaling; p38 MAPK signaling pathway; Pleural mesothelioma; Serotonin HTR1 group and FOS pathway; Serotonin receptor 2 and ELK-SRF/GATA4 signaling; Serotonin receptor 4/6/7 and NR3C signaling"	"Oxidative Stress Induced Senescence; Regulation of HSF1-mediated heat shock response; VEGFA-VEGFR2 Pathway; Regulation of TNFR1 signaling; p38MAPK events; activated TAK1 mediates p38 MAPK activation; CREB phosphorylation; Synthesis of Leukotrienes (LT) and Eoxins (EX); Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"	"21"	"0"	"69.6"	"66.8"	"86.7"	"74.2"	"73.8"	"81.2"	"84.4"	"103.0"	"337.7"	"548.3"	"610.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBB5"	"Methyl-CpG-binding domain protein 2 OS=Homo sapiens OX=9606 GN=MBD2 PE=1 SV=1"	"6"	"2"	"3"	"2"	"411"	"43.2"	"10.04"	"714.59"	"2.62"	"2"	"1"	"cell-cell signaling;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01429, Pf14048, Pf16564"	"8932"	"ENSG00000134046"	"MBD2"	"hsa:8932; O95242; Q9UBB5; Q9UIS8"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"NoRC negatively regulates rRNA expression; RNA Polymerase I Promoter Opening"	"3"	"0"	"6.5"	"10.2"	"11.4"	"6.2"	"13.2"	"11.6"	"13.8"	"21.9"	"33.4"	"60.2"	"75.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A0A087WV53"	"SPEG neighbor protein OS=Homo sapiens OX=9606 GN=SPEGNB PE=4 SV=1"	"7"	"1"	"1"	"1"	"238"	"26.1"	"5.60"	""	"2.62"	""	"1"	""	""	""	"Pf00612, Pf07679"	"100996693"	"ENSG00000286095"	"SPEGNB"	"A0A087WV53; hsa:100996693"	""	""	"0"	"0"	"15.2"	"11.3"	"11.7"	"12.0"	"12.5"	"8.6"	"13.9"	"26.1"	"65.6"	"185.3"	"349.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43707"	"Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2"	"1"	"1"	"2"	"1"	"911"	"104.8"	"5.44"	"313.20"	"2.62"	"1"	"1"	"cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00307, Pf00435, Pf08726"	"81"	"ENSG00000130402; ENSG00000282844"	"ACTN4"	"A4K467; D6PXK4; hsa:81; O43707; O76048"	"Arrhythmogenic right ventricular cardiomyopathy; Primary focal segmental glomerulosclerosis (FSGS); Focal adhesion; Striated muscle contraction pathway; Ebola virus infection in host; Nephrotic syndrome; Alstrom syndrome"	"Platelet degranulation ; Nephrin family interactions"	"9"	"0"	"3.4"	"7.1"	"3.7"	"4.5"	"7.9"	"4.6"	"5.5"	"10.6"	"15.2"	"33.0"	"35.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15347"	"High mobility group protein B3 OS=Homo sapiens OX=9606 GN=HMGB3 PE=1 SV=4"	"11"	"2"	"3"	"2"	"200"	"23.0"	"8.37"	"970.82"	"2.62"	"2"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00505, Pf09011"	"3149"	"ENSG00000029993"	"HMGB3"	"hsa:3149; O15347; O95556; Q6NS40"	""	""	"0"	"0"	"151.0"	"108.3"	"161.8"	"144.1"	"144.2"	"177.2"	"203.1"	"229.2"	"560.5"	"1107.6"	"1367.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7KZI7"	"Serine/threonine-protein kinase MARK2 OS=Homo sapiens OX=9606 GN=MARK2 PE=1 SV=2"	"1"	"1"	"1"	"1"	"788"	"87.9"	"9.72"	""	"2.61"	""	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;kinase activity;other molecular function"	"Pf00069, Pf00627, Pf02149"	"2011"	"ENSG00000072518"	"MARK2"	"hsa:2011; Q15449; Q15524; Q5XGA3; Q68A18; Q7KZI7; Q96HB3; Q96RG0"	"Microtubule cytoskeleton regulation; Complement system in neuronal development and plasticity; Neurogenesis regulation in the olfactory epithelium"	""	"3"	"0"	"104.8"	"46.5"	"75.3"	"131.3"	"84.6"	"108.5"	"60.1"	"135.8"	"225.0"	"284.5"	"323.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09884"	"DNA polymerase alpha catalytic subunit OS=Homo sapiens OX=9606 GN=POLA1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1462"	"165.8"	"5.85"	"351.54"	"2.61"	"1"	"1"	"cell cycle OR cell proliferation;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00136, Pf03104, Pf08996, Pf12254"	"5422"	"ENSG00000101868"	"POLA1"	"hsa:5422; P09884; Q86UQ7"	"Retinoblastoma gene in cancer; Pyrimidine metabolism; DNA replication"	"Activation of the pre-replicative complex; Defective pyroptosis; G1/S-Specific Transcription; Inhibition of replication initiation of damaged DNA by RB1/E2F1; Polymerase switching on the C-strand of the telomere; Telomere C-strand synthesis initiation; DNA replication initiation; Polymerase switching; Removal of the Flap Intermediate"	"13"	"0"	"26.5"	"19.0"	"28.9"	"29.8"	"29.8"	"35.4"	"30.6"	"42.2"	"125.9"	"375.6"	"447.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5TEU4"	"Arginine-hydroxylase NDUFAF5, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFAF5 PE=1 SV=1"	"3"	"1"	"2"	"1"	"345"	"38.9"	"6.57"	"311.05"	"2.60"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf08241"	"79133"	"ENSG00000101247"	"NDUFAF5"	"A8K166; hsa:79133; Q5TEU4; Q6GPH3; Q9H6F4"	""	"Complex I biogenesis"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5V0"	"Zinc finger protein 706 OS=Homo sapiens OX=9606 GN=ZNF706 PE=1 SV=1"	"14"	"1"	"1"	"1"	"76"	"8.5"	"10.01"	""	"2.60"	""	"1"	"other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf04419, Pf12874"	"51123"	"ENSG00000120963"	"ZNF706"	"A8K362; hsa:51123; Q9Y5V0"	""	"Generic Transcription Pathway"	"1"	"0"	"157.4"	"151.7"	"125.4"	"114.4"	"140.1"	"89.2"	"153.9"	"211.8"	"343.6"	"274.2"	"213.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35251"	"Replication factor C subunit 1 OS=Homo sapiens OX=9606 GN=RFC1 PE=1 SV=4"	"1"	"1"	"2"	"1"	"1148"	"128.2"	"9.36"	"368.83"	"2.59"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00004, Pf00533, Pf08519"	"5981"	"ENSG00000035928"	"RFC1"	"A8K6E7; hsa:5981; P35251; Q5XKF5; Q6PKU0; Q86V41; Q86V46"	"miRNA regulation of DNA damage response; DNA replication; Male infertility; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair; DNA damage response"	"PCNA-Dependent Long Patch Base Excision Repair; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; Recognition of DNA damage by PCNA-containing replication complex; Dual Incision in GG-NER; Polymerase switching on the C-strand of the telomere; Polymerase switching; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER"	"22"	"0"	"112.3"	"46.9"	"124.5"	"118.5"	"98.1"	"104.7"	"129.9"	"163.9"	"458.2"	"603.5"	"721.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NRY4"	"Rho GTPase-activating protein 35 OS=Homo sapiens OX=9606 GN=ARHGAP35 PE=1 SV=3"	"1"	"1"	"2"	"1"	"1499"	"170.4"	"6.64"	"278.63"	"2.59"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00071, Pf00620, Pf01846, Pf16512, Pf19518"	"2909"	"ENSG00000160007"	"ARHGAP35"	"A7E2A4; hsa:2909; Q14452; Q9C0E1; Q9NRY4"	"Focal adhesion; Regulation of actin cytoskeleton"	"RND3 GTPase cycle; RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOB GTPase cycle; RND2 GTPase cycle; RHOQ GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOD GTPase cycle; RHOJ GTPase cycle; RND1 GTPase cycle; Sema4D mediated inhibition of cell attachment and migration; PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"	"18"	"0"	"0.0"	"0.0"	"2.8"	"0.0"	"0.0"	"0.0"	"4.4"	"4.6"	"26.7"	"67.1"	"83.9"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WVD3"	"E3 ubiquitin-protein ligase RNF138 OS=Homo sapiens OX=9606 GN=RNF138 PE=1 SV=1"	"4"	"1"	"2"	"1"	"245"	"28.2"	"6.93"	"301.78"	"2.59"	"1"	"1"	"cell-cell signaling;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05605, Pf13923, Pf18574"	"51444"	"ENSG00000134758"	"RNF138"	"B2RE17; hsa:51444; Q8WVD3; Q9H8K2; Q9UF87; Q9UKI6"	""	"Antigen processing: Ubiquitination & Proteasome degradation"	"1"	"0"	"46.4"	"52.1"	"46.6"	"47.7"	"50.9"	"41.2"	"61.0"	"119.3"	"266.8"	"254.8"	"220.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BUR4"	"Telomerase Cajal body protein 1 OS=Homo sapiens OX=9606 GN=WRAP53 PE=1 SV=1"	"3"	"1"	"2"	"1"	"548"	"59.3"	"4.58"	"248.63"	"2.59"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400"	"55135"	"ENSG00000141499"	"WRAP53"	"B3KPR9; D3DTQ4; hsa:55135; Q08ET9; Q9BUR4; Q9NW09"	""	"Association of TriC/CCT with target proteins during biosynthesis; Telomere Extension By Telomerase"	"2"	"0"	"10.8"	"10.6"	"16.9"	"14.6"	"16.5"	"16.1"	"20.5"	"18.9"	"42.6"	"69.3"	"92.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15067"	"Peroxisomal acyl-coenzyme A oxidase 1 OS=Homo sapiens OX=9606 GN=ACOX1 PE=1 SV=3"	"2"	"1"	"2"	"1"	"660"	"74.4"	"8.16"	"320.89"	"2.59"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle"	"other molecular function"	"Pf01756, Pf02770, Pf14749"	"51"	"ENSG00000161533"	"ACOX1"	"A8K6X8; A8KAA0; B4DK61; F5GYQ8; hsa:51; Q12863; Q15067; Q15068; Q15101; Q16131; Q7Z3W5; Q9UD31"	"Estrogen receptor pathway; Nuclear receptors meta-pathway; PPAR signaling pathway; Eicosanoid metabolism via cyclooxygenases (COX); Eicosanoid metabolism via lipooxygenases (LOX); Omega-3 / omega-6 fatty acid synthesis"	"TYSND1 cleaves peroxisomal proteins"	"8"	"0"	"71.9"	"67.8"	"70.5"	"54.4"	"66.4"	"76.6"	"97.5"	"118.3"	"214.0"	"366.5"	"514.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06746"	"DNA polymerase beta OS=Homo sapiens OX=9606 GN=POLB PE=1 SV=3"	"7"	"2"	"3"	"2"	"335"	"38.2"	"8.95"	"647.72"	"2.58"	"2"	"1"	"DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf10391, Pf14716, Pf14791, Pf14792"	"5423"	"ENSG00000070501"	"POLB"	"B2RC78; hsa:5423; P06746; Q3KP48; Q6FI34"	"Male infertility; Base excision repair; DNA repair pathways, full network"	"Ub-specific processing proteases; APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway; POLB-Dependent Long Patch Base Excision Repair; PCNA-Dependent Long Patch Base Excision Repair; Abasic sugar-phosphate removal via the single-nucleotide replacement pathway"	"10"	"0"	"29.1"	"28.0"	"26.8"	"26.1"	"25.0"	"30.5"	"41.9"	"76.4"	"284.5"	"293.9"	"212.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UL40"	"Zinc finger protein 346 OS=Homo sapiens OX=9606 GN=ZNF346 PE=1 SV=1"	"4"	"1"	"1"	"1"	"294"	"32.9"	"9.09"	""	"2.58"	""	"1"	""	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf12874"	"23567"	"ENSG00000113761"	"ZNF346"	"B7Z367; hsa:23567; Q68CV9; Q6ZMW1; Q9UL40"	"5q35 copy number variation"	""	"1"	"0"	"38.8"	"37.6"	"47.7"	"47.4"	"51.3"	"43.4"	"49.1"	"90.5"	"181.1"	"293.1"	"319.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86TN4"	"tRNA 2'-phosphotransferase 1 OS=Homo sapiens OX=9606 GN=TRPT1 PE=1 SV=2"	"4"	"1"	"2"	"1"	"253"	"27.7"	"9.98"	"410.14"	"2.58"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	""	"other molecular function"	"Pf01885"	"83707"	"ENSG00000149743"	"TRPT1"	"A8MU17; A8MYC9; F5H2B2; hsa:83707; Q86TN4; Q9BSB9"	""	""	"0"	"0"	"21.7"	"27.6"	"23.7"	"19.7"	"19.8"	"21.0"	"30.3"	"46.3"	"237.4"	"320.9"	"279.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96MG7"	"Non-structural maintenance of chromosomes element 3 homolog OS=Homo sapiens OX=9606 GN=NSMCE3 PE=1 SV=1"	"4"	"1"	"2"	"1"	"304"	"34.3"	"9.28"	"344.10"	"2.58"	"1"	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf01454"	"56160"	"ENSG00000185115; ENSG00000282130"	"NSMCE3"	"hsa:56160; Q8IW16; Q8TEI6; Q96MG7; Q9H214"	"15q11q13 copy number variation"	"SUMOylation of DNA damage response and repair proteins"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30041"	"Peroxiredoxin-6 OS=Homo sapiens OX=9606 GN=PRDX6 PE=1 SV=3"	"5"	"1"	"2"	"1"	"224"	"25.0"	"6.38"	"367.19"	"2.58"	"1"	"1"	"other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00578, Pf10417"	"9588"	"ENSG00000117592"	"PRDX6"	"A8JZY7; hsa:9588; P30041; P32077; Q5TAH4; Q5ZEZ8"	"Nuclear receptors meta-pathway; NRF2 pathway; VEGFA-VEGFR2 signaling"	"Neutrophil degranulation; Detoxification of Reactive Oxygen Species"	"5"	"0"	"46.2"	"53.5"	"59.2"	"43.0"	"49.6"	"37.1"	"58.8"	"73.4"	"129.5"	"231.0"	"387.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P2F8"	"Signal-induced proliferation-associated 1-like protein 2 OS=Homo sapiens OX=9606 GN=SIPA1L2 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1722"	"190.3"	"6.77"	"277.14"	"2.58"	"1"	"1"	"other biological processes"	"other cell component"	"enzyme regulator activity"	"Pf00595, Pf02145, Pf11881"	"57568"	"ENSG00000116991"	"SIPA1L2"	"hsa:57568; Q2TV88; Q5VXR7; Q5VXR8; Q641Q4; Q8NA38; Q96DZ3; Q9H9F6; Q9P2F8"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P20073"	"Annexin A7 OS=Homo sapiens OX=9606 GN=ANXA7 PE=1 SV=3"	"2"	"1"	"2"	"1"	"488"	"52.7"	"5.68"	"313.16"	"2.58"	"1"	"1"	"other metabolic processes;other biological processes"	"other membranes;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00191"	"310"	"ENSG00000138279"	"ANXA7"	"hsa:310; P20073; Q5F2H3; Q5T0M6; Q5T0M7"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q08AD1"	"Calmodulin-regulated spectrin-associated protein 2 OS=Homo sapiens OX=9606 GN=CAMSAP2 PE=1 SV=3"	"2"	"2"	"3"	"2"	"1489"	"168.0"	"6.80"	"522.24"	"2.58"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;ER/Golgi"	"cytoskeletal activity;other molecular function"	"Pf08683, Pf11971, Pf17095"	"23271"	"ENSG00000118200"	"CAMSAP2"	"B1APG6; hsa:23271; Q08AD1; Q08AD2; Q6PGN8; Q96FB3; Q9UG20; Q9UPS4"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15532"	"Protein SSXT OS=Homo sapiens OX=9606 GN=SS18 PE=1 SV=3"	"3"	"1"	"2"	"1"	"418"	"45.9"	"6.46"	"277.56"	"2.58"	"1"	"1"	"cell organization and biogenesis;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf05030"	"6760"	"ENSG00000141380"	"SS18"	"B0YJ95; hsa:6760; Q15532; Q16404; Q4VAX1; Q9BXC6"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16527"	"Cysteine and glycine-rich protein 2 OS=Homo sapiens OX=9606 GN=CSRP2 PE=1 SV=3"	"4"	"1"	"2"	"1"	"193"	"20.9"	"8.62"	"258.24"	"2.56"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412"	"1466"	"ENSG00000175183"	"CSRP2"	"hsa:1466; Q16527; Q93030"	"Mesodermal commitment pathway; VEGFA-VEGFR2 signaling; H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity"	""	"3"	"0"	"336.7"	"345.2"	"310.0"	"274.3"	"342.0"	"298.5"	"411.4"	"412.5"	"485.0"	"730.6"	"745.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14258"	"E3 ubiquitin/ISG15 ligase TRIM25 OS=Homo sapiens OX=9606 GN=TRIM25 PE=1 SV=2"	"2"	"1"	"2"	"1"	"630"	"70.9"	"8.09"	"249.58"	"2.56"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00622, Pf13445, Pf13765"	"7706"	"ENSG00000121060"	"TRIM25"	"hsa:7706; Q14258"	"Novel intracellular components of RIG-I-like receptor pathway; Cytosolic DNA-sensing pathway; SARS-CoV-2 innate immunity evasion and cell-specific immune response; 1p36 copy number variation syndrome"	"SARS-CoV-1 activates/modulates innate immune responses; ISG15 antiviral mechanism; Interferon gamma signaling; SARS-CoV-2 activates/modulates innate and adaptive immune responses; TRAF6 mediated NF-kB activation; NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10; Termination of translesion DNA synthesis; Negative regulators of DDX58/IFIH1 signaling; Ovarian tumor domain proteases; TRAF3-dependent IRF activation pathway; TRAF6 mediated IRF7 activation"	"16"	"0"	"6.1"	"5.0"	"8.5"	"3.8"	"8.2"	"8.9"	"7.1"	"15.9"	"32.6"	"81.9"	"96.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86U44"	"N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2"	"4"	"2"	"3"	"2"	"580"	"64.4"	"6.42"	"650.02"	"2.56"	"2"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05063"	"56339"	"ENSG00000165819"	"METTL3"	"hsa:56339; O14736; Q86U44; Q86V05; Q9HB32"	"mRNA processing"	"Processing of Capped Intron-Containing Pre-mRNA"	"2"	"0"	"149.7"	"122.2"	"141.6"	"123.5"	"145.8"	"126.8"	"153.1"	"183.7"	"347.4"	"749.4"	"1040.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UJ04"	"Testis-specific Y-encoded-like protein 4 OS=Homo sapiens OX=9606 GN=TSPYL4 PE=1 SV=2"	"2"	"1"	"2"	"1"	"414"	"45.1"	"8.57"	"311.45"	"2.56"	"1"	"1"	"cell organization and biogenesis"	"nucleus;other cell component"	"other molecular function"	"Pf00956"	"23270"	"ENSG00000187189"	"TSPYL4"	"B4DYQ2; hsa:23270; O94828; Q96GW8; Q9UJ04"	""	""	"0"	"0"	"32.3"	"26.2"	"27.3"	"29.3"	"30.6"	"29.0"	"30.7"	"35.9"	"40.3"	"45.2"	"42.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6IQ49"	"Replication stress response regulator SDE2 OS=Homo sapiens OX=9606 GN=SDE2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"451"	"49.7"	"6.05"	"299.10"	"2.56"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity"	"Pf13019, Pf13297"	"163859"	"ENSG00000143751"	"SDE2"	"A8K4P3; hsa:163859; Q5TD36; Q6IQ49; Q6ZS26; Q8NAG7"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"145.6"	"109.8"	"130.5"	"107.8"	"133.5"	"118.8"	"157.2"	"193.7"	"300.5"	"506.6"	"714.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q10472"	"Polypeptide N-acetylgalactosaminyltransferase 1 OS=Homo sapiens OX=9606 GN=GALNT1 PE=1 SV=1"	"2"	"1"	"2"	"1"	"559"	"64.2"	"7.72"	"304.51"	"2.55"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf00535, Pf00652"	"2589"	"ENSG00000141429"	"GALNT1"	"hsa:2589; Q10472; Q86TJ7; Q9UM86"	"Metabolism of sphingolipids in ER and Golgi apparatus"	"COPI-independent Golgi-to-ER retrograde traffic; O-linked glycosylation of mucins; Maturation of protein 3a; Maturation of protein 3a"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5TAX3"	"Terminal uridylyltransferase 4 OS=Homo sapiens OX=9606 GN=TUT4 PE=1 SV=3"	"1"	"1"	"2"	"1"	"1644"	"185.0"	"7.97"	"297.51"	"2.55"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00098, Pf01909, Pf03828, Pf19088"	"23318"	"ENSG00000134744"	"TUT4"	"A2RRP0; B7Z8J5; D3DQ35; hsa:23318; Q12764; Q5TAX2; Q5TAX3; Q5TAX4; Q86XZ3"	""	"Deadenylation of mRNA"	"1"	"0"	"4.7"	"4.3"	"4.4"	"6.7"	"8.6"	"8.7"	"9.0"	"10.4"	"30.6"	"58.1"	"55.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A3KN83"	"Protein strawberry notch homolog 1 OS=Homo sapiens OX=9606 GN=SBNO1 PE=1 SV=1"	"1"	"1"	"1"	"1"	"1393"	"154.2"	"7.88"	""	"2.54"	""	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf13871, Pf13872"	"55206"	"ENSG00000139697"	"SBNO1"	"A3KN83; hsa:55206; Q05C06; Q3ZTS3; Q9H3T8; Q9NVB2"	""	""	"0"	"0"	"4.2"	"0.0"	"2.7"	"0.0"	"2.6"	"5.4"	"5.0"	"4.1"	"18.9"	"164.5"	"242.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UJX3"	"Anaphase-promoting complex subunit 7 OS=Homo sapiens OX=9606 GN=ANAPC7 PE=1 SV=4"	"2"	"1"	"2"	"1"	"599"	"66.8"	"5.64"	"373.59"	"2.54"	"1"	"1"	""	""	""	"Pf13432"	"51434"	""	"ANAPC7"	"A0A024RBJ3; hsa:51434"	""	""	"0"	"0"	"29.6"	"34.3"	"17.6"	"20.8"	"28.4"	"28.9"	"32.1"	"41.4"	"65.0"	"179.6"	"299.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BV38"	"WD repeat-containing protein 18 OS=Homo sapiens OX=9606 GN=WDR18 PE=1 SV=2"	"4"	"2"	"3"	"2"	"432"	"47.4"	"6.70"	"553.67"	"2.54"	"2"	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf00400, Pf14077"	"57418"	"ENSG00000065268"	"WDR18"	"hsa:57418; O60390; Q9BV38; Q9BWR2"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"119.0"	"102.6"	"160.1"	"120.7"	"109.5"	"118.4"	"156.9"	"187.0"	"267.6"	"319.1"	"428.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05783"	"Keratin, type I cytoskeletal 18 OS=Homo sapiens OX=9606 GN=KRT18 PE=1 SV=2"	"4"	"2"	"3"	"1"	"430"	"48.0"	"5.45"	"641.03"	"2.54"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00038"	"3875"	"ENSG00000111057"	"KRT18"	"hsa:3875; P05783; Q53G38; Q5U0N8; Q9BW26"	"Pathogenic Escherichia coli infection"	"Formation of the cornified envelope"	"3"	"0"	"9.0"	"11.6"	"10.0"	"7.2"	"9.9"	"8.4"	"11.7"	"21.8"	"41.7"	"87.3"	"118.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UPZ3"	"Hermansky-Pudlak syndrome 5 protein OS=Homo sapiens OX=9606 GN=HPS5 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1129"	"127.4"	"5.54"	"347.06"	"2.54"	"1"	"1"	"cell organization and biogenesis;stress response;transport;other biological processes"	"cytosol;other cytoplasmic organelle;other cell component"	""	""	"11234"	"ENSG00000110756; ENSG00000288445"	"HPS5"	"A8K6J8; A8K8S1; D3DQX9; D3DQY0; hsa:11234; O95942; Q8N4U0; Q9UPZ3"	""	""	"0"	"0"	"6.9"	"5.7"	"8.2"	"5.6"	"10.6"	"5.8"	"9.8"	"9.4"	"20.2"	"38.7"	"52.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99963"	"Endophilin-A3 OS=Homo sapiens OX=9606 GN=SH3GL3 PE=1 SV=1"	"4"	"1"	"1"	"1"	"347"	"39.3"	"5.38"	""	"2.54"	""	"1"	"cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"other membranes;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00018, Pf03114"	"6457"	"ENSG00000140600"	"SH3GL3"	"hsa:6457; O43553; O43554; Q99963"	"EGF/EGFR signaling pathway; Fragile X syndrome; 10q22q23 copy number variation; 15q25 copy number variation"	"NGF-stimulated transcription; Cargo recognition for clathrin-mediated endocytosis; EGFR downregulation; Negative regulation of MET activity; InlB-mediated entry of Listeria monocytogenes into host cell"	"10"	"0"	"237.8"	"223.0"	"237.8"	"168.7"	"247.1"	"236.9"	"272.7"	"348.3"	"381.6"	"617.9"	"709.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H8W4"	"Pleckstrin homology domain-containing family F member 2 OS=Homo sapiens OX=9606 GN=PLEKHF2 PE=1 SV=1"	"5"	"1"	"2"	"1"	"249"	"27.8"	"8.21"	"333.38"	"2.54"	"1"	"1"	"cell organization and biogenesis;transport"	"other membranes;ER/Golgi;other cytoplasmic organelle"	"other molecular function"	"Pf00169, Pf01363"	"79666"	"ENSG00000175895"	"PLEKHF2"	"hsa:79666; Q9H8W4"	""	""	"0"	"0"	"3.4"	"3.8"	"3.7"	"2.3"	"5.7"	"3.0"	"5.3"	"14.4"	"37.9"	"60.3"	"43.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IZH2"	"5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1"	"1"	"1"	"1"	"1"	"1706"	"194.0"	"7.21"	""	"2.54"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03159, Pf17846, Pf18129, Pf18332, Pf18334"	"54464"	"ENSG00000114127"	"XRN1"	"hsa:54464; Q4G0S3; Q68D88; Q6AI24; Q6MZS8; Q86WS7; Q8IZH2; Q8N8U4; Q9UF39"	"miRNA degrading enzymes"	"mRNA decay by 5' to 3' exoribonuclease; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"	"4"	"0"	"6.3"	"4.6"	"7.9"	"4.3"	"7.6"	"7.1"	"6.1"	"14.1"	"21.4"	"25.4"	"48.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NR12"	"PDZ and LIM domain protein 7 OS=Homo sapiens OX=9606 GN=PDLIM7 PE=1 SV=1"	"6"	"2"	"3"	"2"	"457"	"49.8"	"8.41"	"680.94"	"2.53"	"2"	"1"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412, Pf00595"	"9260"	"ENSG00000196923"	"PDLIM7"	"hsa:9260; Q14250; Q5XG82; Q6NVZ5; Q96C91; Q9BXB8; Q9BXB9; Q9NR12"	"Ebstein-Barr virus LMP1 signaling; GDNF signaling; 5q35 copy number variation"	"RET signaling"	"4"	"0"	"34.3"	"36.6"	"42.6"	"33.7"	"41.7"	"42.9"	"53.7"	"58.7"	"119.8"	"262.3"	"356.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P21359"	"Neurofibromin OS=Homo sapiens OX=9606 GN=NF1 PE=1 SV=2"	"0"	"1"	"2"	"1"	"2839"	"319.2"	"7.39"	"309.13"	"2.53"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00616, Pf13716"	"4763"	"ENSG00000196712"	"NF1"	"hsa:4763; O00662; P21359; Q14284; Q14930; Q14931; Q9UMK3"	"Pilocytic astrocytoma; Glioblastoma signaling pathways; Aryl hydrocarbon receptor pathway; MECP2 and associated Rett syndrome; MAPK signaling pathway; Ras signaling; Transcription co-factors SKI and SKIL protein partners; Synaptic signaling pathways associated with autism spectrum disorder; Fragile X syndrome; Melanoma; EGFR tyrosine kinase inhibitor resistance"	"Regulation of RAS by GAPs; RAS signaling downstream of NF1 loss-of-function variants"	"13"	"0"	"21.1"	"20.8"	"23.0"	"20.9"	"22.5"	"20.2"	"23.0"	"32.3"	"74.6"	"117.5"	"150.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H3T2"	"Semaphorin-6C OS=Homo sapiens OX=9606 GN=SEMA6C PE=2 SV=4"	"3"	"1"	"1"	"1"	"930"	"99.6"	"8.03"	""	"2.53"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"signal transduction activity or receptor binding"	"Pf01403"	"10500"	"ENSG00000143434"	"SEMA6C"	"D3DV15; hsa:10500; Q5JR71; Q5JR72; Q5JR73; Q8WXT8; Q8WXT9; Q8WXU0; Q96JF8; Q9H3T2"	"IL-18 signaling pathway"	""	"1"	"0"	"100.1"	"91.5"	"128.5"	"96.3"	"78.4"	"64.7"	"124.1"	"212.4"	"354.5"	"399.6"	"381.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00429"	"Dynamin-1-like protein OS=Homo sapiens OX=9606 GN=DNM1L PE=1 SV=2"	"1"	"1"	"2"	"1"	"736"	"81.8"	"6.81"	"325.55"	"2.53"	"1"	"1"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00350, Pf01031, Pf02212"	"10059"	"ENSG00000087470"	"DNM1L"	"A8K4X9; B4DGC9; B4DSU8; G8JLD5; hsa:10059; J3KPI2; O00429; O14541; O60709; Q59GN9; Q7L6B3; Q8TBT7; Q9BWM1; Q9Y5J2"	"Synaptic vesicle pathway; CAMKK2 pathway"	"Apoptotic execution phase"	"3"	"0"	"41.1"	"37.4"	"44.6"	"38.4"	"40.0"	"45.2"	"56.7"	"58.6"	"92.1"	"453.2"	"806.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P98095"	"Fibulin-2 OS=Homo sapiens OX=9606 GN=FBLN2 PE=1 SV=2"	"1"	"1"	"1"	"1"	"1184"	"126.5"	"4.82"	""	"2.52"	""	"1"	"other biological processes"	"extracellular matrix"	"extracellular structural activity;other molecular function"	"Pf01821, Pf07645, Pf12662, Pf14670"	"2199"	"ENSG00000163520"	"FBLN2"	"B7Z9C5; hsa:2199; P98095; Q8IUI0; Q8IUI1"	"7q11.23 copy number variation syndrome"	"Molecules associated with elastic fibres"	"2"	"0"	"82.6"	"45.6"	"121.1"	"92.4"	"112.4"	"170.5"	"291.6"	"476.1"	"637.3"	"446.1"	"400.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43313"	"ATM interactor OS=Homo sapiens OX=9606 GN=ATMIN PE=1 SV=2"	"2"	"1"	"1"	"1"	"823"	"88.3"	"5.16"	""	"2.52"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	""	"23300"	"ENSG00000166454"	"ATMIN"	"A8K4H8; hsa:23300; O43313; Q68DC9"	"ATM signaling in development and disease"	""	"1"	"0"	"20.8"	"16.1"	"34.8"	"29.3"	"30.7"	"36.0"	"34.2"	"36.2"	"71.6"	"117.8"	"124.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WTT2"	"Nucleolar complex protein 3 homolog OS=Homo sapiens OX=9606 GN=NOC3L PE=1 SV=1"	"1"	"1"	"2"	"1"	"800"	"92.5"	"9.17"	"298.50"	"2.52"	"1"	"1"	"DNA metabolism;other metabolic processes;other biological processes"	"mitochondrion;nucleus"	"other molecular function"	"Pf03914, Pf07540"	"64318"	"ENSG00000173145"	"NOC3L"	"hsa:64318; Q8WTT2; Q9H5M6; Q9H9D8"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UNW9"	"RNA-binding protein Nova-2 OS=Homo sapiens OX=9606 GN=NOVA2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"492"	"49.0"	"8.16"	"245.85"	"2.52"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00013"	"4858"	"ENSG00000104967"	"NOVA2"	"hsa:4858; O43267; Q9UEA1; Q9UNW9"	""	""	"0"	"0"	"80.6"	"69.8"	"85.4"	"79.3"	"83.6"	"93.9"	"82.5"	"100.9"	"131.6"	"215.6"	"305.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75689"	"Arf-GAP with dual PH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ADAP1 PE=1 SV=2"	"6"	"3"	"4"	"3"	"374"	"43.4"	"8.97"	"840.30"	"2.52"	"3"	"1"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf01412"	"11033"	"ENSG00000105963"	"ADAP1"	"A4D2Q2; B3KRZ4; B4DVA6; F6XZ68; H7C2Q4; hsa:11033; O75689"	""	"Nuclear signaling by ERBB4"	"1"	"0"	"114.5"	"105.6"	"117.0"	"99.6"	"127.2"	"196.8"	"372.0"	"829.1"	"1475.6"	"1288.9"	"1041.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08183"	"ATP-dependent translocase ABCB1 OS=Homo sapiens OX=9606 GN=ABCB1 PE=1 SV=3"	"2"	"1"	"1"	"1"	"1280"	"141.4"	"9.00"	""	"2.51"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;other cell component"	"transporter activity;other molecular function"	"Pf00005, Pf00664"	"5243"	"ENSG00000085563"	"ABCB1"	"A8K294; B5AK60; hsa:5243; P08183; Q12755; Q14812"	"Codeine and morphine metabolism; Drug induction of bile acid pathway; Allograft rejection; Constitutive androstane receptor pathway; Pregnane X receptor pathway; Vitamin D receptor pathway; Nuclear receptors meta-pathway; Nuclear receptors in lipid metabolism and toxicity; Imatinib and chronic myeloid leukemia; lncRNA-mediated mechanisms of therapeutic resistance; Male infertility; Proximal tubule transport"	"ABC-family proteins mediated transport; Abacavir transmembrane transport; Prednisone ADME; Atorvastatin ADME"	"16"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P47755"	"F-actin-capping protein subunit alpha-2 OS=Homo sapiens OX=9606 GN=CAPZA2 PE=1 SV=3"	"6"	"1"	"2"	"1"	"286"	"32.9"	"5.85"	"408.10"	"2.51"	"1"	"1"	"cell organization and biogenesis"	"non-structural extracellular;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf01267"	"830"	"ENSG00000198898"	"CAPZA2"	"B4DG50; hsa:830; P47755"	""	"Sensory processing of sound by inner hair cells of the cochlea; MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Factors involved in megakaryocyte development and platelet production; Advanced glycosylation endproduct receptor signaling"	"7"	"0"	"6.5"	"8.2"	"5.5"	"7.0"	"4.6"	"3.6"	"9.8"	"11.8"	"35.3"	"108.7"	"192.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5VZE5"	"N-alpha-acetyltransferase 35, NatC auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA35 PE=1 SV=1"	"2"	"1"	"2"	"1"	"725"	"83.6"	"7.05"	"279.81"	"2.51"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	""	"Pf04112"	"60560"	"ENSG00000135040"	"NAA35"	"hsa:60560; Q5VZE5; Q5VZE6; Q9H631; Q9H703"	""	"Retrograde transport at the Trans-Golgi-Network"	"1"	"0"	"4.2"	"0.0"	"2.4"	"2.6"	"0.0"	"2.1"	"0.0"	"5.6"	"17.9"	"48.6"	"67.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12797"	"Aspartyl/asparaginyl beta-hydroxylase OS=Homo sapiens OX=9606 GN=ASPH PE=1 SV=3"	"3"	"2"	"3"	"2"	"758"	"85.8"	"5.01"	"762.75"	"2.50"	"2"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi"	"other molecular function"	"Pf05118, Pf05279, Pf13432"	"444"	"ENSG00000198363"	"ASPH"	"A0A0A0MSK8; A6NDF4; A6NHI2; B4DIC9; B4E2K4; B7ZM95; E5RGP5; F5H667; hsa:444; Q12797; Q6NXR7; Q8TB28; Q9H291; Q9H2C4; Q9NRI0; Q9NRI1; Q9Y4J0"	""	"Stimuli-sensing channels; Ion homeostasis"	"2"	"0"	"37.4"	"42.3"	"35.1"	"26.5"	"41.1"	"38.4"	"47.6"	"71.3"	"452.6"	"1040.6"	"1125.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BX40"	"Protein LSM14 homolog B OS=Homo sapiens OX=9606 GN=LSM14B PE=1 SV=1"	"7"	"2"	"3"	"1"	"385"	"42.0"	"9.69"	"506.33"	"2.50"	"1"	"1"	"other biological processes"	"other cell component"	"nucleic acid binding activity"	"Pf09532, Pf12701"	"149986"	"ENSG00000149657"	"LSM14B"	"hsa:149986; Q6PFW8; Q96LH8; Q9BX40"	""	""	"0"	"0"	"33.4"	"32.3"	"32.8"	"21.8"	"30.9"	"35.7"	"49.8"	"45.8"	"53.5"	"133.8"	"133.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13416"	"Origin recognition complex subunit 2 OS=Homo sapiens OX=9606 GN=ORC2 PE=1 SV=2"	"2"	"2"	"3"	"2"	"577"	"65.9"	"6.51"	"569.70"	"2.50"	"2"	"1"	"DNA metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity"	"Pf04084"	"4999"	"ENSG00000115942"	"ORC2"	"hsa:4999; Q13204; Q13416; Q53TX5"	"Cell cycle; G1 to S cell cycle control; DNA replication"	"Activation of ATR in response to replication stress; Orc1 removal from chromatin; Activation of the pre-replicative complex; E2F-enabled inhibition of pre-replication complex formation; Assembly of the ORC complex at the origin of replication; CDC6 association with the ORC:origin complex"	"10"	"0"	"350.3"	"254.3"	"346.1"	"324.0"	"342.0"	"351.7"	"369.8"	"377.5"	"824.5"	"1929.7"	"2579.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4C2"	"TRPM8 channel-associated factor 1 OS=Homo sapiens OX=9606 GN=TCAF1 PE=1 SV=3"	"1"	"1"	"1"	"1"	"921"	"102.1"	"6.54"	""	"2.50"	""	"1"	"other biological processes"	"plasma membrane;other membranes"	"other molecular function"	"Pf13402, Pf17291"	"9747"	"ENSG00000198420"	"TCAF1"	"A8K6E0; hsa:9747; Q75KM8; Q75KM9; Q7L665; Q9BW63; Q9Y4C2"	""	""	"0"	"0"	"26.4"	"13.1"	"33.5"	"25.2"	"26.2"	"31.9"	"38.3"	"40.9"	"112.5"	"189.4"	"234.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HC38"	"Glyoxalase domain-containing protein 4 OS=Homo sapiens OX=9606 GN=GLOD4 PE=1 SV=1"	"4"	"1"	"2"	"1"	"313"	"34.8"	"5.60"	"272.42"	"2.49"	"1"	"1"	""	"mitochondrion"	""	""	"51031"	"ENSG00000167699"	"GLOD4"	"D3DTG9; D3DTH1; hsa:51031; Q96B89; Q9H3J8; Q9HC37; Q9HC38; Q9NVN1"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96B97"	"SH3 domain-containing kinase-binding protein 1 OS=Homo sapiens OX=9606 GN=SH3KBP1 PE=1 SV=2"	"3"	"1"	"2"	"1"	"665"	"73.1"	"6.62"	"320.92"	"2.49"	"1"	"1"	"cell-cell signaling;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf14604"	"30011"	"ENSG00000147010"	"SH3KBP1"	"B7Z1D5; hsa:30011; Q5JPT4; Q5JPT5; Q8IWX6; Q8IX98; Q96B97; Q96RN4; Q9NYR0"	"EGF/EGFR signaling pathway"	"Potential therapeutics for SARS; Cargo recognition for clathrin-mediated endocytosis; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; EGFR downregulation; Negative regulation of MET activity; InlB-mediated entry of Listeria monocytogenes into host cell; Reelin signalling pathway"	"9"	"0"	"5.6"	"0.0"	"7.9"	"6.4"	"8.1"	"7.3"	"10.2"	"11.1"	"12.8"	"32.1"	"60.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08240"	"Signal recognition particle receptor subunit alpha OS=Homo sapiens OX=9606 GN=SRPRA PE=1 SV=2"	"2"	"1"	"2"	"1"	"638"	"69.8"	"8.95"	"282.23"	"2.49"	"1"	"1"	"cell organization and biogenesis;transport"	"other membranes;ER/Golgi"	"other molecular function"	"Pf00448, Pf02881, Pf04086"	"6734"	"ENSG00000182934"	"SRPRA"	"A6NIB3; B2R5Z8; B4E0H3; E9PJS4; hsa:6734; P08240; Q9BVJ4"	""	"SRP-dependent cotranslational protein targeting to membrane; XBP1(S) activates chaperone genes"	"2"	"0"	"3.9"	"5.1"	"4.4"	"4.1"	"5.7"	"2.4"	"4.3"	"4.6"	"25.6"	"43.7"	"49.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86WB0"	"Nuclear-interacting partner of ALK OS=Homo sapiens OX=9606 GN=ZC3HC1 PE=1 SV=1"	"4"	"1"	"1"	"1"	"502"	"55.2"	"5.62"	""	"2.49"	""	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"other membranes;nucleus"	"other molecular function"	"Pf07967, Pf08600"	"51530"	"ENSG00000091732"	"ZC3HC1"	"A6NH66; hsa:51530; Q75MF3; Q75MF4; Q86WB0; Q8N330; Q96F75; Q9HA34; Q9NVX4; Q9P0R0"	""	"Nuclear events stimulated by ALK signaling in cancer"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"P82663"	"28S ribosomal protein S25, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS25 PE=1 SV=1"	"6"	"1"	"2"	"1"	"173"	"20.1"	"8.82"	"255.57"	"2.49"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf05047"	"64432"	"ENSG00000131368"	"MRPS25"	"B4DFJ5; B4DQG6; hsa:64432; P82663; Q9H7P5"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P0C7P4"	"Putative cytochrome b-c1 complex subunit Rieske-like protein 1 OS=Homo sapiens OX=9606 GN=UQCRFS1P1 PE=5 SV=1"	"3"	"1"	"2"	"1"	"283"	"30.8"	"8.87"	"239.75"	"2.49"	"1"	"1"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00355, Pf02921, Pf09165"	""	""	"UQCRFS1P1"	"P0C7P4"	""	""	"0"	"0"	"86.1"	"83.5"	"77.7"	"78.3"	"92.6"	"79.7"	"96.9"	"104.6"	"141.5"	"235.8"	"324.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8ND04"	"Protein SMG8 OS=Homo sapiens OX=9606 GN=SMG8 PE=1 SV=1"	"1"	"1"	"2"	"1"	"991"	"109.6"	"7.68"	"273.58"	"2.48"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol"	""	"Pf10220"	"55181"	"ENSG00000167447"	"SMG8"	"hsa:55181; Q8N5U5; Q8ND04; Q8TDN0; Q9H5P5; Q9NVQ1"	""	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50213"	"Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3A PE=1 SV=1"	"2"	"1"	"2"	"1"	"366"	"39.6"	"6.92"	"284.99"	"2.48"	"1"	"1"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00180"	"3419"	"ENSG00000166411"	"IDH3A"	"D3DW83; hsa:3419; P50213; Q9H3X0"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Metabolic reprogramming in colon cancer; TCA cycle (aka Krebs or citric acid cycle)"	"Citric acid cycle (TCA cycle)"	"4"	"0"	"59.6"	"56.8"	"50.9"	"44.6"	"58.5"	"55.0"	"71.6"	"79.8"	"107.1"	"378.7"	"900.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14976"	"Cyclin-G-associated kinase OS=Homo sapiens OX=9606 GN=GAK PE=1 SV=2"	"1"	"1"	"2"	"1"	"1311"	"143.1"	"5.73"	"301.26"	"2.48"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;ER/Golgi;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf10409"	"2580"	"ENSG00000178950"	"GAK"	"hsa:2580; O14976; Q5U4P5; Q9BVY6"	""	"Golgi Associated Vesicle Biogenesis; Clathrin-mediated endocytosis"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BZ29"	"Dedicator of cytokinesis protein 9 OS=Homo sapiens OX=9606 GN=DOCK9 PE=1 SV=2"	"1"	"1"	"1"	"1"	"2069"	"236.3"	"7.49"	""	"2.48"	""	"1"	"signal transduction;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity"	"Pf00169, Pf06920, Pf11878, Pf14429, Pf20421, Pf20422"	"23348"	"ENSG00000088387"	"DOCK9"	"B3KX25; E9PFM9; hsa:23348; Q5JUD4; Q5JUD6; Q5T2Q1; Q5TAN8; Q9BZ25; Q9BZ26; Q9BZ27; Q9BZ28; Q9BZ29; Q9UPU4"	""	"CDC42 GTPase cycle; RAC1 GTPase cycle; Factors involved in megakaryocyte development and platelet production"	"3"	"0"	"14.2"	"16.8"	"19.6"	"13.3"	"23.4"	"52.8"	"109.4"	"154.7"	"142.6"	"258.3"	"224.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95299"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFA10 PE=1 SV=1"	"3"	"1"	"2"	"1"	"355"	"40.7"	"8.48"	"241.66"	"2.48"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion;other cell component"	"transporter activity"	"Pf01712"	"4705"	"ENSG00000130414"	"NDUFA10"	"hsa:4705; O95299; Q8WXC9"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; 2q37 copy number variation syndrome; Oxidative phosphorylation"	"Complex I biogenesis"	"6"	"0"	"56.0"	"62.1"	"48.4"	"46.7"	"57.3"	"38.8"	"58.3"	"80.3"	"110.4"	"195.7"	"282.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TB45"	"DEP domain-containing mTOR-interacting protein OS=Homo sapiens OX=9606 GN=DEPTOR PE=1 SV=2"	"2"	"1"	"2"	"1"	"409"	"46.3"	"8.07"	"284.19"	"2.47"	"1"	"1"	"cell organization and biogenesis;signal transduction;other biological processes"	""	""	"Pf00610"	"64798"	"ENSG00000155792"	"DEPTOR"	"B2RCL9; B4DN97; E7EV87; hsa:64798; Q8TB45; Q96EQ1; Q9H0R7; Q9H894; Q9HA07"	"Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; Clear cell renal cell carcinoma pathways; Fragile X syndrome; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Autophagy; p53 transcriptional gene network; Pleural mesothelioma; Network map of SARS-CoV-2 signaling pathway; DYRK1A involvement regarding cell proliferation in brain development"	""	"9"	"0"	"7.7"	"8.2"	"6.6"	"7.1"	"10.9"	"9.1"	"9.4"	"12.2"	"37.2"	"76.3"	"90.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P54132"	"Bloom syndrome protein OS=Homo sapiens OX=9606 GN=BLM PE=1 SV=1"	"1"	"1"	"2"	"1"	"1417"	"158.9"	"7.49"	"375.23"	"2.47"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf00570, Pf08072, Pf09382, Pf16124, Pf16202, Pf16204"	"641"	"ENSG00000197299"	"BLM"	"hsa:641; P54132; Q52M96"	"Primary ovarian insufficiency"	"HDR through Single Strand Annealing (SSA); Resolution of D-loop Structures through Holliday Junction Intermediates; SUMOylation of DNA damage response and repair proteins; Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; Meiotic recombination; Impaired BRCA2 binding to RAD51; Processive synthesis on the C-strand of the telomere"	"18"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q53GQ0"	"Very-long-chain 3-oxoacyl-CoA reductase OS=Homo sapiens OX=9606 GN=HSD17B12 PE=1 SV=2"	"4"	"1"	"1"	"1"	"312"	"34.3"	"9.32"	""	"2.47"	""	"1"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"extracellular matrix;other membranes;ER/Golgi"	"other molecular function"	"Pf00106"	"51144"	"ENSG00000149084"	"HSD17B12"	"A8K9B0; D3DR23; hsa:51144; Q53GQ0; Q96EA9; Q96JU2; Q9Y6G8"	"Mitochondrial fatty acid synthesis pathway"	"Synthesis of very long-chain fatty acyl-CoAs; Androgen biosynthesis"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6VY07"	"Phosphofurin acidic cluster sorting protein 1 OS=Homo sapiens OX=9606 GN=PACS1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"963"	"104.8"	"7.74"	"333.75"	"2.46"	"1"	"1"	"other biological processes"	"cytosol;ER/Golgi"	"other molecular function"	"Pf10254"	"55690"	"ENSG00000175115"	"PACS1"	"hsa:55690; Q6PJY6; Q6PKB6; Q6VY07; Q7Z590; Q7Z5W4; Q8N8K6; Q96MW0; Q9NW92; Q9ULP5"	""	"Nef mediated downregulation of MHC class I complex cell surface expression"	"1"	"0"	"19.3"	"18.7"	"20.0"	"20.8"	"20.6"	"20.6"	"22.5"	"27.7"	"62.9"	"112.6"	"137.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TBF4"	"Zinc finger CCHC-type and RNA-binding motif-containing protein 1 OS=Homo sapiens OX=9606 GN=ZCRB1 PE=1 SV=2"	"5"	"1"	"2"	"1"	"217"	"24.6"	"8.53"	"274.64"	"2.46"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf00076, Pf00098"	"85437"	"ENSG00000139168"	"ZCRB1"	"hsa:85437; Q6PJX0; Q8TBF4; Q96TA6"	""	"mRNA Splicing - Minor Pathway; Replication of the SARS-CoV-1 genome; Replication of the SARS-CoV-2 genome"	"3"	"0"	"20.8"	"16.8"	"13.4"	"15.5"	"17.9"	"11.7"	"19.8"	"17.5"	"27.3"	"39.1"	"51.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25788"	"Proteasome subunit alpha type-3 OS=Homo sapiens OX=9606 GN=PSMA3 PE=1 SV=2"	"5"	"1"	"2"	"1"	"255"	"28.4"	"5.33"	"357.42"	"2.46"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00227, Pf10584"	"5684"	"ENSG00000100567"	"PSMA3"	"B2RCK6; hsa:5684; P25788; Q86U83; Q8N1D8; Q9BS70"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Separation of Sister Chromatids; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"62"	"0"	"134.4"	"76.3"	"214.3"	"161.3"	"144.7"	"155.0"	"176.9"	"161.2"	"280.2"	"313.1"	"465.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49685"	"G-protein coupled receptor 15 OS=Homo sapiens OX=9606 GN=GPR15 PE=2 SV=1"	"3"	"1"	"1"	"1"	"360"	"40.8"	"8.72"	""	"2.46"	""	"1"	"developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00001"	"2838"	"ENSG00000154165"	"GPR15"	"hsa:2838; P49685; Q3MIL4; Q6ISN6"	"GPCRs, class A rhodopsin-like; 10q22q23 copy number variation"	"G alpha (s) signalling events"	"3"	"0"	"165.2"	"178.4"	"275.3"	"230.6"	"252.6"	"251.3"	"285.0"	"354.3"	"691.5"	"1098.6"	"1540.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P27986"	"Phosphatidylinositol 3-kinase regulatory subunit alpha OS=Homo sapiens OX=9606 GN=PIK3R1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"724"	"83.5"	"6.16"	"248.56"	"2.45"	"1"	"1"	"cell adhesion;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00017, Pf00620, Pf16454"	"5295"	"ENSG00000145675"	"PIK3R1"	"B3KT19; D3DWA0; E7EX19; hsa:5295; P27986; Q15747; Q4VBZ7; Q53EM6; Q8IXA2; Q8N1C5"	"IL-5 signaling pathway; Androgen receptor signaling pathway; AMP-activated protein kinase signaling; MicroRNAs in cardiomyocyte hypertrophy; IL-1 signaling pathway; RANKL/RANK signaling pathway; Thyroid stimulating hormone (TSH) signaling pathway; Leptin signaling pathway; Prolactin signaling pathway; IL-7 signaling pathway; Alzheimer's disease and miRNA effects; IL-9 signaling pathway; Glioblastoma signaling pathways; B cell receptor signaling pathway; Interleukin-11 signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Alpha 6 beta 4 signaling pathway; Apoptosis; Bladder cancer; IL-3 signaling pathway; Kit receptor signaling pathway; Focal adhesion; RAC1/PAK1/p38/MMP2 pathway; IL6 signaling pathway; PI3K-AKT-mTOR signaling pathway and therapeutic opportunities in prostate cancer; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Microglia pathogen phagocytosis pathway; IL-4 signaling pathway; Endometrial cancer; PI3K-Akt signaling pathway; Ebola virus infection in host; Ras signaling; Epithelial to mesenchymal transition in colorectal cancer; Non-small cell lung cancer; Breast cancer pathway; Pancreatic adenocarcinoma pathway; Acute viral myocarditis; EGF/EGFR signaling pathway; Nonalcoholic fatty liver disease; Synaptic signaling pathways associated with autism spectrum disorder; Overview of interferons-mediated signaling pathway; Translation inhibitors in chronically activated PDGFRA cells; Cancer immunotherapy by CTLA4 blockade; Measles virus infection; Small cell lung cancer; Gastrin signaling pathway; Hepatitis B infection; Head and neck squamous cell carcinoma; Melanoma; IL-18 signaling pathway; Osteoblast differentiation and related diseases; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; mBDNF and proBDNF regulation of GABA neurotransmission; IL-2 signaling pathway; Modulators of TCR signaling and T cell activation; Orexin receptor pathway; CCL18 signaling pathway; Regulation of actin cytoskeleton; Alzheimer's disease; GDNF signaling; TROP2 regulatory signaling; A network map of Macrophage-stimulating protein (MSP) signaling; 4p16.3 copy number variation; 5q35 copy number variation; Interferon type I signaling pathways; Notch signaling pathway; ErbB signaling pathway; T-cell receptor signaling pathway; DNA damage response (only ATM dependent); Toll-like receptor signaling pathway"	"RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOB GTPase cycle; Signaling by cytosolic FGFR1 fusion mutants; Signaling by FGFR1 in disease; RHOJ GTPase cycle; G alpha (q) signalling events; Role of phospholipids in phagocytosis; Role of LAT2/NTAL/LAB on calcium mobilization; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Downstream TCR signaling; RND2 GTPase cycle; RHOG GTPase cycle; RHOD GTPase cycle; RHOF GTPase cycle; Extra-nuclear estrogen signaling; RHOV GTPase cycle; PIP3 activates AKT signaling; Signaling by ALK fusions and activated point mutants; RHOU GTPase cycle; Synthesis of PIPs at the plasma membrane; Constitutive Signaling by Aberrant PI3K in Cancer; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; RET signaling; Erythropoietin activates Phosphoinositide-3-kinase (PI3K); Interleukin receptor SHC signaling; Regulation of signaling by CBL; Nephrin family interactions; RAF/MAP kinase cascade; PI3K Cascade; GPVI-mediated activation cascade; Interleukin-7 signaling; Signaling by SCF-KIT; Downstream signal transduction; PI3K/AKT activation; Signaling by ALK; Tie2 Signaling; DAP12 signaling; Costimulation by the CD28 family; CD28 dependent PI3K/Akt signaling; VEGFA-VEGFR2 Pathway; Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants; Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants; Signaling by PDGFRA extracellular domain mutants; RND3 GTPase cycle; RND1 GTPase cycle; Interleukin-4 and Interleukin-13 signaling; PI3K events in ERBB4 signaling; PI3K events in ERBB2 signaling; Signaling by ERBB2 KD Mutants; GAB1 signalosome; Signaling by CSF1 (M-CSF) in myeloid cells; PI-3K cascade:FGFR1; PI-3K cascade:FGFR2; Signaling by FGFR2 in disease; PI-3K cascade:FGFR3; PI-3K cascade:FGFR4; Signaling by FGFR3 in disease; FLT3 Signaling; Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; Constitutive Signaling by EGFRvIII; Signaling by ERBB2 ECD mutants; Signaling by FGFR4 in disease; Signaling by FLT3 fusion proteins; Signaling by FLT3 ITD and TKD mutants; GP1b-IX-V activation signalling; MET activates PI3K/AKT signaling; Activated NTRK3 signals through PI3K; Activated NTRK2 signals through PI3K"	"150"	"0"	"67.1"	"32.7"	"68.5"	"75.0"	"50.4"	"84.7"	"104.7"	"145.8"	"226.9"	"197.0"	"306.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75306"	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2"	"3"	"1"	"2"	"1"	"463"	"52.5"	"7.55"	"283.81"	"2.45"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"other membranes;mitochondrion;nucleus"	"transporter activity;other molecular function"	"Pf00346"	"4720"	"ENSG00000158864"	"NDUFS2"	"D3DVG7; hsa:4720; J3KPM7; O75306; Q5VTW0; Q969P3; Q9UEV3"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"22.3"	"25.1"	"27.9"	"29.6"	"24.6"	"23.1"	"28.2"	"28.6"	"57.4"	"115.3"	"136.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HAS0"	"Protein Njmu-R1 OS=Homo sapiens OX=9606 GN=C17orf75 PE=1 SV=2"	"3"	"1"	"2"	"1"	"396"	"44.6"	"5.03"	"300.22"	"2.44"	"1"	"1"	"cell organization and biogenesis;transport"	"ER/Golgi;other cell component"	""	"Pf15053"	"64149"	"ENSG00000108666"	"C17orf75"	"hsa:64149; Q7Z2H4; Q9HAS0"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61927"	"60S ribosomal protein L37 OS=Homo sapiens OX=9606 GN=RPL37 PE=1 SV=2"	"6"	"1"	"1"	"1"	"97"	"11.1"	"11.74"	""	"2.44"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf01907"	"6167"	"ENSG00000145592"	"RPL37"	"B2R4H2; hsa:6167; P02403; P61927; Q6IBB4; Q99883"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis"	"14"	"0"	"443.8"	"451.8"	"293.8"	"328.2"	"355.9"	"357.4"	"469.4"	"573.4"	"629.0"	"1058.3"	"1659.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5VST9"	"Obscurin OS=Homo sapiens OX=9606 GN=OBSCN PE=1 SV=3"	"0"	"1"	"1"	"1"	"7968"	"867.9"	"5.99"	""	"2.44"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus"	"enzyme regulator activity;cytoskeletal activity;kinase activity;other molecular function"	"Pf00041, Pf00069, Pf00612, Pf00621, Pf07679"	"84033"	"ENSG00000154358"	"OBSCN"	"hsa:84033; Q2A664; Q5T7G8; Q5T7G9; Q5VST9; Q5VSU2; Q86YC7; Q8NHN0; Q8NHN1; Q8NHN2; Q8NHN3; Q8NHN4; Q8NHN5; Q8NHN6; Q8NHN7; Q8NHN8; Q8NHN9; Q96AA2; Q9HCD3; Q9HCL6"	""	"RHOA GTPase cycle; NRAGE signals death through JNK; G alpha (12/13) signalling events; RHOQ GTPase cycle"	"4"	"0"	"62.2"	"27.5"	"153.3"	"109.8"	"93.3"	"117.0"	"111.6"	"89.6"	"191.4"	"161.8"	"239.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96CW5"	"Gamma-tubulin complex component 3 OS=Homo sapiens OX=9606 GN=TUBGCP3 PE=1 SV=2"	"1"	"1"	"1"	"1"	"907"	"103.5"	"8.12"	""	"2.44"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf04130, Pf17681"	"10426"	"ENSG00000126216"	"TUBGCP3"	"hsa:10426; O43631; O60852; O60853; Q5T8L2; Q7Z4K1; Q96CW5; Q96I79"	"Prader-Willi and Angelman syndrome; 15q11.2 copy number variation syndrome"	"Recruitment of NuMA to mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"E9PRG8"	"Uncharacterized protein C11orf98 OS=Homo sapiens OX=9606 GN=C11orf98 PE=4 SV=2"	"7"	"1"	"2"	"1"	"123"	"14.2"	"11.53"	"316.54"	"2.43"	"1"	"1"	""	""	""	"Pf17719"	"102288414"	"ENSG00000278615"	"C11orf98"	"A0A0B4J220; E9PRG8; hsa:102288414"	""	""	"0"	"0"	"111.2"	"105.9"	"122.2"	"107.3"	"138.8"	"128.4"	"137.4"	"150.4"	"193.6"	"282.5"	"353.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60496"	"Docking protein 2 OS=Homo sapiens OX=9606 GN=DOK2 PE=1 SV=2"	"3"	"1"	"1"	"1"	"412"	"45.4"	"6.02"	""	"2.43"	""	"1"	"signal transduction;other biological processes"	"cytosol;other cell component"	"signal transduction activity or receptor binding"	"Pf02174"	"9046"	"ENSG00000147443"	"DOK2"	"hsa:9046; O60496; Q8N5A4"	"RAC1/PAK1/p38/MMP2 pathway; IL-4 signaling pathway; EGF/EGFR signaling pathway"	"RET signaling; Tie2 Signaling"	"5"	"0"	"128.8"	"41.4"	"253.7"	"166.9"	"225.5"	"220.1"	"157.6"	"148.4"	"377.2"	"531.3"	"832.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16222"	"UDP-N-acetylhexosamine pyrophosphorylase OS=Homo sapiens OX=9606 GN=UAP1 PE=1 SV=3"	"2"	"1"	"1"	"1"	"522"	"58.7"	"6.33"	""	"2.43"	""	"1"	"other metabolic processes"	"plasma membrane;other membranes;cytosol;nucleus"	"other molecular function"	"Pf01704"	"6675"	"ENSG00000117143"	"UAP1"	"B2R6R8; hsa:6675; Q16222; Q5VTA9; Q5VTB0; Q5VTB1; Q96GM2"	""	"Synthesis of UDP-N-acetyl-glucosamine"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N5L8"	"Ribonuclease P protein subunit p25-like protein OS=Homo sapiens OX=9606 GN=RPP25L PE=1 SV=1"	"6"	"1"	"2"	"1"	"163"	"17.6"	"10.30"	"269.96"	"2.43"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf01918"	"138716"	"ENSG00000164967"	"RPP25L"	"D3DRM5; hsa:138716; Q8N5L8"	""	""	"0"	"0"	"73.5"	"47.8"	"80.2"	"63.9"	"66.2"	"71.7"	"90.2"	"106.9"	"144.5"	"196.2"	"292.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IYI6"	"Exocyst complex component 8 OS=Homo sapiens OX=9606 GN=EXOC8 PE=1 SV=2"	"2"	"1"	"2"	"1"	"725"	"81.7"	"5.49"	"313.90"	"2.43"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf08700, Pf16528"	"149371"	"ENSG00000116903"	"EXOC8"	"B3KU33; hsa:149371; Q5TE82; Q8IYI6"	"RalA downstream regulated genes; Ciliary landscape"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BUA3"	"Spindlin interactor and repressor of chromatin-binding protein OS=Homo sapiens OX=9606 GN=SPINDOC PE=1 SV=3"	"2"	"1"	"2"	"1"	"381"	"41.0"	"5.01"	"318.92"	"2.43"	"1"	"1"	"stress response;other biological processes"	"nucleus;other cell component"	""	"Pf18658"	"144097"	"ENSG00000168005"	"SPINDOC"	"hsa:144097; Q68CV7; Q6PHS2; Q96IH0; Q9BUA3"	""	""	"0"	"0"	"55.2"	"58.7"	"51.5"	"42.6"	"63.9"	"63.4"	"65.4"	"91.8"	"214.6"	"535.2"	"725.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15154"	"Pericentriolar material 1 protein OS=Homo sapiens OX=9606 GN=PCM1 PE=1 SV=5"	"0"	"1"	"2"	"1"	"2024"	"228.4"	"5.02"	"392.57"	"2.42"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf15717"	"5108"	"ENSG00000078674"	"PCM1"	"A6NNN6; B4DYD5; E7ETA6; E7EV56; hsa:5108; Q15154; Q58F13; Q6P1K7; Q8NB85; Q9BWC1; Q9H4A2"	"Prader-Willi and Angelman syndrome; Joubert syndrome"	"Regulation of PLK1 Activity at G2/M Transition; Recruitment of NuMA to mitotic centrosomes; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"9"	"0"	"62.1"	"69.8"	"53.0"	"49.0"	"55.5"	"47.1"	"64.6"	"84.4"	"101.8"	"124.5"	"190.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61758"	"Prefoldin subunit 3 OS=Homo sapiens OX=9606 GN=VBP1 PE=1 SV=4"	"4"	"1"	"2"	"1"	"197"	"22.6"	"7.11"	"266.16"	"2.42"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02996"	"7411"	"ENSG00000155959"	"VBP1"	"B2R8L5; B4DWR3; F5H2A7; hsa:7411; O55228; P61758; Q15765; Q5JT81; Q86X96"	"Cellular proteostasis"	"Prefoldin mediated transfer of substrate  to CCT/TriC"	"2"	"0"	"39.1"	"44.9"	"39.1"	"31.5"	"44.3"	"35.4"	"45.1"	"55.6"	"114.7"	"279.7"	"524.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11182"	"Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DBT PE=1 SV=3"	"3"	"1"	"2"	"1"	"482"	"53.5"	"8.51"	"272.43"	"2.42"	"1"	"1"	"other metabolic processes"	"cytosol;cytoskeleton;mitochondrion;other cell component"	"other molecular function"	"Pf00198, Pf00364, Pf02817"	"1629"	"ENSG00000137992"	"DBT"	"B2R811; hsa:1629; P11182; Q5VVL8"	""	"Glyoxylate metabolism and glycine degradation; Branched-chain amino acid catabolism; RHOH GTPase cycle"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H270"	"Vacuolar protein sorting-associated protein 11 homolog OS=Homo sapiens OX=9606 GN=VPS11 PE=1 SV=1"	"1"	"1"	"1"	"1"	"941"	"107.8"	"7.05"	""	"2.41"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00637, Pf12451, Pf13923"	"55823"	""	"VPS11"	"hsa:55823; Q8WY89; Q96EP8; Q9H270; Q9H6D9; Q9HCS6"	"Network map of SARS-CoV-2 signaling pathway"	"SARS-CoV-2 modulates autophagy"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2P8"	"RNA 3'-terminal phosphate cyclase-like protein OS=Homo sapiens OX=9606 GN=RCL1 PE=1 SV=3"	"3"	"1"	"2"	"1"	"373"	"40.8"	"9.26"	"395.20"	"2.41"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf01137, Pf05189"	"10171"	"ENSG00000120158"	"RCL1"	"D3DRI2; hsa:10171; Q5VYW9; Q5VZU1; Q9H9D0; Q9NY00; Q9P044; Q9Y2P8"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"13.7"	"14.5"	"13.5"	"12.3"	"13.9"	"10.8"	"14.4"	"19.9"	"32.5"	"49.8"	"65.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4K4"	"Mitogen-activated protein kinase kinase kinase kinase 5 OS=Homo sapiens OX=9606 GN=MAP4K5 PE=1 SV=2"	"1"	"1"	"2"	"1"	"846"	"95.0"	"7.83"	"285.45"	"2.41"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction"	"plasma membrane;other membranes;cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00780"	"11183"	"ENSG00000012983"	"MAP4K5"	"A0A0A0MQR1; hsa:11183; Q8IYF6; Q9Y4K4"	"Angiopoietin-like protein 8 regulatory pathway; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Insulin signaling"	""	"3"	"0"	"82.4"	"96.1"	"99.6"	"76.5"	"97.6"	"76.0"	"114.3"	"152.9"	"224.2"	"330.7"	"281.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96DX7"	"Tripartite motif-containing protein 44 OS=Homo sapiens OX=9606 GN=TRIM44 PE=1 SV=1"	"3"	"1"	"2"	"1"	"344"	"38.4"	"4.21"	"341.44"	"2.41"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other cell component"	"other molecular function"	"Pf00643"	"54765"	"ENSG00000166326"	"TRIM44"	"D3DR14; hsa:54765; Q96DX7; Q96QY2; Q9UGK0"	""	""	"0"	"0"	"5.8"	"7.8"	"9.0"	"7.8"	"5.5"	"8.1"	"9.5"	"12.3"	"18.6"	"39.6"	"54.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H977"	"WD repeat-containing protein 54 OS=Homo sapiens OX=9606 GN=WDR54 PE=1 SV=1"	"4"	"1"	"1"	"1"	"334"	"35.9"	"6.20"	""	"2.41"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"other molecular function"	""	"84058"	"ENSG00000005448"	"WDR54"	"B9A049; D6W5I3; hsa:84058; Q53H85; Q86V45; Q9H977"	""	""	"0"	"0"	"47.9"	"21.3"	"94.3"	"58.1"	"64.5"	"64.2"	"97.8"	"115.8"	"366.3"	"576.4"	"1044.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BRP4"	"Proteasomal ATPase-associated factor 1 OS=Homo sapiens OX=9606 GN=PAAF1 PE=1 SV=2"	"3"	"1"	"1"	"1"	"392"	"42.2"	"6.32"	""	"2.41"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf00400"	"80227"	"ENSG00000175575"	"PAAF1"	"A6NDR5; B4DPB0; B7ZAS9; hsa:80227; Q4G165; Q53HS9; Q7Z500; Q8TBU6; Q9BRP4; Q9HAB6"	""	""	"0"	"0"	"22.8"	"16.9"	"24.1"	"23.6"	"22.7"	"29.2"	"35.5"	"48.2"	"70.7"	"205.4"	"366.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A4D1P6"	"WD repeat-containing protein 91 OS=Homo sapiens OX=9606 GN=WDR91 PE=1 SV=2"	"1"	"1"	"1"	"1"	"747"	"83.3"	"6.58"	""	"2.41"	""	"1"	"transport;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle"	"enzyme regulator activity"	"Pf00400"	"29062"	"ENSG00000105875"	"WDR91"	"A4D1P6; A6NK54; C9JMI4; hsa:29062; Q6FI65; Q6MZQ1; Q6P4I1; Q96AE5; Q96G63; Q9H062; Q9H9B6; Q9NVG7; Q9NZY6"	""	"CDC42 GTPase cycle"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95801"	"Tetratricopeptide repeat protein 4 OS=Homo sapiens OX=9606 GN=TTC4 PE=1 SV=3"	"3"	"1"	"2"	"1"	"387"	"44.7"	"5.60"	"254.59"	"2.40"	"1"	"1"	"protein metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf18972"	"7268"	"ENSG00000243725"	"TTC4"	"hsa:7268; O95801; Q53Y95; Q5TA96; Q9H3I2"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P28482"	"Mitogen-activated protein kinase 1 OS=Homo sapiens OX=9606 GN=MAPK1 PE=1 SV=3"	"2"	"1"	"2"	"1"	"360"	"41.4"	"6.98"	"309.75"	"2.40"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00069"	"5594"	"ENSG00000100030"	"MAPK1"	"A8CZ64; hsa:5594; P28482"	"IL-5 signaling pathway; Osteopontin signaling; Physiological and pathological hypertrophy of the heart; Angiogenesis; MicroRNAs in cardiomyocyte hypertrophy; Type II diabetes mellitus; Heart development; Integrin-mediated cell adhesion; IL-1 signaling pathway; Thyroxine (thyroid hormone) production; RANKL/RANK signaling pathway; Thyroid stimulating hormone (TSH) signaling pathway; Leptin signaling pathway; Follicle stimulating hormone (FSH) signaling pathway; TNF-related weak inducer of apoptosis (TWEAK) signaling pathway; Prolactin signaling pathway; IL-7 signaling pathway; Alzheimer's disease and miRNA effects; IL-17 signaling pathway; Endothelin pathways; IL-9 signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; Glioblastoma signaling pathways; Androgen receptor network in prostate cancer; B cell receptor signaling pathway; TNF-alpha signaling pathway; AGE/RAGE pathway; Interleukin-11 signaling pathway; Corticotropin-releasing hormone signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Spinal cord injury; Alpha 6 beta 4 signaling pathway; PDGF pathway; Aryl hydrocarbon receptor pathway; S1P receptor signal transduction; Ebstein-Barr virus LMP1 signaling; Common pathways underlying drug addiction; Interleukin-1 (IL-1) structural pathway; Cardiac hypertrophic response; Bladder cancer; IL-3 signaling pathway; Apoptosis-related network due to altered Notch3 in ovarian cancer; TCA cycle nutrient use and invasiveness of ovarian cancer; Kit receptor signaling pathway; Focal adhesion; Hepatocyte growth factor receptor signaling; MFAP5-mediated ovarian cancer cell motility and invasiveness; RAC1/PAK1/p38/MMP2 pathway; Wnt signaling pathway; IL6 signaling pathway; Hypothesized pathways in pathogenesis of cardiovascular disease; BDNF-TrkB signaling; Physico-chemical features and toxicity-associated pathways; MAPK signaling pathway; MAPK and NFkB signaling pathways inhibited by Yersinia YopJ; ERK pathway in Huntington's disease; Toll-like receptor signaling related to MyD88; TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition; 4-hydroxytamoxifen, dexamethasone, and retinoic acids regulation of p27 expression; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Chemokine signaling pathway; Embryonic stem cell pluripotency pathways; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; IL-4 signaling pathway; Prion disease pathway; Endometrial cancer; PI3K-Akt signaling pathway; Chromosomal and microsatellite instability in colorectal cancer ; Ebola virus infection in host; MAPK cascade; Ras signaling; Epithelial to mesenchymal transition in colorectal cancer; Non-small cell lung cancer; Breast cancer pathway; Pancreatic adenocarcinoma pathway; Acute viral myocarditis; Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells; Neovascularisation processes; Non-genomic actions of 1,25 dihydroxyvitamin D3; EGF/EGFR signaling pathway; Bile acids synthesis and enterohepatic circulation ; Resistin as a regulator of inflammation; Relationship between inflammation, COX-2 and EGFR; Envelope proteins and their potential roles in EDMD physiopathology; Regulatory circuits of the STAT3 signaling pathway; Synaptic signaling pathways associated with autism spectrum disorder; Fragile X syndrome; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Translation inhibitors in chronically activated PDGFRA cells; Gastrin signaling pathway; Hepatitis B infection; Melanoma; Netrin-UNC5B signaling pathway; IL-18 signaling pathway; FGFR3 signaling in chondrocyte proliferation and terminal differentiation; Osteoblast differentiation and related diseases; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; Regucalcin in proximal tubule epithelial kidney cells; Kisspeptin/kisspeptin receptor system in the ovary; MAP3K1 role in promoting and blocking gonadal determination; CAMKK2 pathway; Disruption of postsynaptic signaling by CNV; Host-pathogen interaction of human coronaviruses - MAPK signaling; IL-2 signaling pathway; RAS and bradykinin pathways in COVID-19; Angiotensin II receptor type 1 pathway; Kallmann syndrome; Neuroinflammation and glutamatergic signaling; Pleural mesothelioma; Orexin receptor pathway; CCL18 signaling pathway; Regulation of actin cytoskeleton; Sphingolipid metabolism in senescence; Alzheimer's disease; Th17 cell differentiation pathway; GDNF signaling; 2q11.2 copy number variation syndrome; 2q13 copy number variation syndrome; Hippocampal synaptogenesis and neurogenesis; Comprehensive IL-17A signaling; Genetic causes of porto-sinusoidal vascular disease; Female steroid hormones in cardiomyocyte energy metabolism; Cardiomyocyte signaling pathways converging on Titin; 8p23.1 copy number variation syndrome; IL-26 signaling pathways; A network map of Macrophage-stimulating protein (MSP) signaling; 4p16.3 copy number variation; Role of hypoxia, angiogenesis, and FGF pathway in OA chondrocyte hypertrophy; NPHP1 deletion syndrome; EPO receptor signaling; ErbB signaling pathway; T-cell receptor signaling pathway; DNA damage response (only ATM dependent); Estrogen signaling pathway; Vitamin A and carotenoid metabolism; Toll-like receptor signaling pathway"	"NPAS4 regulates expression of target genes; Estrogen-dependent nuclear events downstream of ESR-membrane signaling; Recycling pathway of L1; Downregulation of SMAD2/3:SMAD4 transcriptional activity; Neutrophil degranulation; Regulation of HSF1-mediated heat shock response; Regulation of actin dynamics for phagocytic cup formation; FCERI mediated MAPK activation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Signaling by BRAF and RAF1 fusions; Thrombin signalling through proteinase activated receptors (PARs); SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Oxidative Stress Induced Senescence; Regulation of PTEN gene transcription; Signaling by NODAL; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Interferon gamma signaling; Oncogene Induced Senescence; Senescence-Associated Secretory Phenotype (SASP); Growth hormone receptor signaling; Regulation of the apoptosome activity; Signal transduction by L1; NCAM signaling for neurite out-growth; RUNX2 regulates osteoblast differentiation; RSK activation; Estrogen-stimulated signaling through PRKCZ; Spry regulation of FGF signaling; Suppression of apoptosis; MAPK1 (ERK2) activation; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; IFNG signaling activates MAPKs; Golgi Cisternae Pericentriolar Stack Reorganization; Signaling by Activin; Activation of the AP-1 family of transcription factors; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; Frs2-mediated activation; Signal attenuation; Gastrin-CREB signalling pathway via PKC and MAPK; Nuclear events stimulated by ALK signaling in cancer; ESR-mediated signaling; Negative feedback regulation of MAPK pathway; Advanced glycosylation endproduct receptor signaling; RHO GTPases Activate NADPH Oxidases; ERKs are inactivated; Signaling by MAP2K mutants; phospho-PLA2 pathway; Signaling by MAPK mutants"	"200"	"0"	"104.6"	"123.7"	"117.4"	"89.7"	"112.2"	"122.4"	"139.1"	"245.8"	"392.4"	"719.8"	"1151.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43166"	"Signal-induced proliferation-associated 1-like protein 1 OS=Homo sapiens OX=9606 GN=SIPA1L1 PE=1 SV=4"	"1"	"1"	"1"	"1"	"1804"	"199.9"	"8.19"	""	"2.40"	""	"1"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity"	"Pf02145, Pf11881"	"26037"	"ENSG00000197555"	"SIPA1L1"	"hsa:26037; J3KP19; O43166; O95321; Q9UDU4; Q9UNU4"	""	"Neurexins and neuroligins"	"1"	"0"	"7.1"	"9.1"	"9.6"	"6.6"	"8.7"	"10.6"	"8.4"	"8.6"	"17.4"	"16.6"	"26.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6DKI1"	"60S ribosomal protein L7-like 1 OS=Homo sapiens OX=9606 GN=RPL7L1 PE=1 SV=2"	"4"	"2"	"3"	"2"	"255"	"29.7"	"10.52"	"748.90"	"2.40"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes"	"cytosol;translational apparatus;nucleus"	"other molecular function"	"Pf00327, Pf08079"	"285855"	"ENSG00000146223"	"RPL7L1"	"A8K7D4; B7Z652; hsa:285855; Q5TFZ5; Q6DKI1; Q6PEK3"	""	""	"0"	"0"	"83.6"	"80.3"	"93.8"	"81.8"	"75.2"	"84.2"	"100.1"	"121.2"	"159.0"	"239.9"	"338.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P39880"	"Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3"	"1"	"1"	"2"	"1"	"1505"	"164.1"	"5.90"	"291.51"	"2.40"	"1"	"1"	"other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00046, Pf02376"	"1523"	"ENSG00000257923"	"CUX1"	"B3KV79; J3KQV9; P39880; Q6NYH4; Q75LE5; Q75MT2; Q75MT3; Q86UJ7; Q9UEV5"	""	"Signaling by FGFR1 in disease; Signaling by cytosolic FGFR1 fusion mutants"	"2"	"0"	"2.4"	"4.5"	"4.9"	"8.2"	"7.7"	"7.9"	"8.1"	"20.3"	"46.8"	"45.3"	"55.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IXS8"	"Protein FAM126B OS=Homo sapiens OX=9606 GN=FAM126B PE=1 SV=1"	"2"	"1"	"2"	"1"	"530"	"58.6"	"7.90"	"315.33"	"2.40"	"1"	"1"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol"	""	"Pf09790"	"285172"	"ENSG00000155744"	"HYCC2"	"B2RCG7; hsa:285172; Q4ZG87; Q53TX6; Q8IXS8"	""	""	"0"	"0"	"14.5"	"7.0"	"13.5"	"12.3"	"13.9"	"13.0"	"17.2"	"18.7"	"55.0"	"103.3"	"131.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62310"	"U6 snRNA-associated Sm-like protein LSm3 OS=Homo sapiens OX=9606 GN=LSM3 PE=1 SV=2"	"8"	"1"	"2"	"1"	"102"	"11.8"	"4.70"	"275.83"	"2.39"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01423"	"27258"	"ENSG00000170860"	"LSM3"	"hsa:27258; P62310; Q6IAH0; Q9Y4Z1"	""	"mRNA Splicing - Major Pathway; mRNA decay by 5' to 3' exoribonuclease"	"2"	"0"	"138.7"	"78.3"	"162.5"	"130.8"	"140.0"	"139.0"	"165.7"	"180.4"	"268.3"	"335.6"	"638.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95373"	"Importin-7 OS=Homo sapiens OX=9606 GN=IPO7 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1038"	"119.4"	"4.82"	"257.72"	"2.39"	"1"	"1"	"stress response;transport;other biological processes"	"cytosol;nucleus"	"enzyme regulator activity;other molecular function"	"Pf03810, Pf08506"	"10527"	"ENSG00000205339"	"IPO7"	"A6NNM5; B2R786; hsa:10527; O95373; Q1RMF7; Q9H177; Q9NTE3"	""	""	"0"	"0"	"0.0"	"0.0"	"0.0"	"2.7"	"0.0"	"0.0"	"3.1"	"4.9"	"10.5"	"32.0"	"72.3"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14174"	"Macrophage migration inhibitory factor OS=Homo sapiens OX=9606 GN=MIF PE=1 SV=4"	"11"	"1"	"2"	"1"	"115"	"12.5"	"7.88"	"352.08"	"2.39"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;stress response;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01187"	"4282"	"ENSG00000240972; ENSG00000276701"	"MIF"	"A5Z1R8; B2R4S3; hsa:4282; P14174; Q2V4Y5; Q6FHV0"	"Adipogenesis; Spinal cord injury"	"Neutrophil degranulation; Cell surface interactions at the vascular wall; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	"5"	"0"	"138.3"	"125.2"	"135.2"	"161.5"	"90.3"	"81.1"	"128.9"	"166.9"	"170.3"	"234.0"	"264.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P28290"	"Protein ITPRID2 OS=Homo sapiens OX=9606 GN=ITPRID2 PE=1 SV=3"	"0"	"1"	"2"	"1"	"1259"	"138.3"	"5.19"	"251.52"	"2.39"	"1"	"1"	""	"plasma membrane;other membranes;cytosol;nucleus"	"signal transduction activity or receptor binding;cytoskeletal activity"	"Pf14722, Pf14723"	"6744"	"ENSG00000138434"	"ITPRID2"	"A8K6T0; hsa:6744; P28290; Q68DA6; Q7Z7L2; Q8N1L3; Q8N263; Q8N7H2; Q8NEN5; Q96E36; Q96PW1"	""	""	"0"	"0"	"115.9"	"108.1"	"118.7"	"95.3"	"121.5"	"105.5"	"115.8"	"154.7"	"229.1"	"467.2"	"799.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4W6"	"AFG3-like protein 2 OS=Homo sapiens OX=9606 GN=AFG3L2 PE=1 SV=2"	"2"	"2"	"3"	"1"	"797"	"88.5"	"8.66"	"673.23"	"2.39"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf00004, Pf01434, Pf06480, Pf17862"	"10939"	"ENSG00000141385"	"AFG3L2"	"hsa:10939; Q6P1L0; Q9Y4W6"	"Ciliary landscape; 10q22q23 copy number variation"	"Processing of SMDT1"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H871"	"E3 ubiquitin-protein transferase RMND5A OS=Homo sapiens OX=9606 GN=RMND5A PE=1 SV=1"	"3"	"1"	"1"	"1"	"391"	"44.0"	"6.06"	""	"2.38"	""	"1"	"protein metabolism;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf10607, Pf13445"	"64795"	"ENSG00000153561"	"RMND5A"	"D6W5M6; hsa:64795; Q6NTF0; Q9H6W5; Q9H871; Q9H9H2"	"Ciliary landscape"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13823"	"Nucleolar GTP-binding protein 2 OS=Homo sapiens OX=9606 GN=GNL2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"731"	"83.6"	"9.25"	"337.07"	"2.38"	"1"	"1"	"other biological processes"	"nucleus"	"other molecular function"	"Pf01926, Pf08153"	"29889"	"ENSG00000134697"	"GNL2"	"hsa:29889; Q13823; Q9BWN7"	""	""	"0"	"0"	"4.0"	"3.2"	"8.0"	"5.4"	"7.2"	"5.1"	"7.4"	"7.7"	"14.4"	"23.5"	"25.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7LBR1"	"Charged multivesicular body protein 1b OS=Homo sapiens OX=9606 GN=CHMP1B PE=1 SV=1"	"3"	"1"	"1"	"1"	"199"	"22.1"	"8.10"	""	"2.38"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf03357"	"57132"	"ENSG00000255112"	"CHMP1B"	"hsa:57132; Q7LBR1; Q96E89; Q9HD41"	""	""	"0"	"0"	"109.9"	"70.6"	"111.3"	"99.9"	"138.8"	"134.8"	"188.9"	"357.3"	"803.9"	"560.5"	"444.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5T447"	"E3 ubiquitin-protein ligase HECTD3 OS=Homo sapiens OX=9606 GN=HECTD3 PE=1 SV=1"	"2"	"1"	"2"	"1"	"861"	"97.1"	"5.64"	"367.78"	"2.38"	"1"	"1"	"protein metabolism;other metabolic processes"	"other cell component"	"other molecular function"	"Pf00632, Pf03256"	"79654"	"ENSG00000126107"	"HECTD3"	"B3KPV7; B3KRH4; hsa:79654; Q5T447; Q5T448; Q9H783"	""	"Antigen processing: Ubiquitination & Proteasome degradation"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9ULW0"	"Targeting protein for Xklp2 OS=Homo sapiens OX=9606 GN=TPX2 PE=1 SV=2"	"1"	"1"	"2"	"1"	"747"	"85.6"	"9.23"	"308.40"	"2.38"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf06886, Pf09041, Pf12214"	"22974"	"ENSG00000088325"	"TPX2"	"hsa:22974; Q96RR5; Q9H1R4; Q9NRA3; Q9UFN9; Q9UL00; Q9ULW0; Q9Y2M1"	"Gastric cancer network 1"	"Regulation of TP53 Activity through Phosphorylation; AURKA Activation by TPX2"	"3"	"0"	"64.5"	"61.6"	"65.7"	"56.0"	"66.9"	"63.8"	"75.2"	"83.8"	"114.9"	"182.7"	"269.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5PSV4"	"Breast cancer metastasis-suppressor 1-like protein OS=Homo sapiens OX=9606 GN=BRMS1L PE=1 SV=2"	"4"	"1"	"1"	"1"	"323"	"37.6"	"5.15"	""	"2.38"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf08598"	"84312"	"ENSG00000100916"	"BRMS1L"	"A6NFW5; A6NH45; B2RD65; hsa:84312; Q5PSV4; Q9BRI4"	""	""	"0"	"0"	"0.0"	"2.4"	"5.1"	"6.0"	"4.5"	"3.5"	"8.0"	"10.5"	"17.2"	"41.0"	"56.5"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NG48"	"Protein Lines homolog 1 OS=Homo sapiens OX=9606 GN=LINS1 PE=1 SV=2"	"1"	"1"	"1"	"1"	"757"	"85.8"	"6.52"	""	"2.37"	""	"1"	"other biological processes"	""	""	"Pf14694, Pf14695"	"55180"	"ENSG00000140471"	"LINS1"	"hsa:55180; Q8NG48; Q96FW2; Q9NVQ3"	""	""	"0"	"0"	"137.9"	"121.8"	"129.5"	"123.6"	"127.5"	"135.2"	"155.0"	"163.3"	"207.0"	"398.9"	"760.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96NL6"	"Sodium channel and clathrin linker 1 OS=Homo sapiens OX=9606 GN=SCLT1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"688"	"80.9"	"6.07"	"241.22"	"2.37"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes"	"other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	""	"132320"	"ENSG00000151466"	"SCLT1"	"A4QN04; hsa:132320; Q0VAH2; Q6P2M4; Q96NL6"	"Genes related to primary cilium development (based on CRISPR); Ciliopathies; Bardet-Biedl syndrome"	"Anchoring of the basal body to the plasma membrane"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EY4"	"Translation machinery-associated protein 16 OS=Homo sapiens OX=9606 GN=TMA16 PE=1 SV=2"	"5"	"1"	"2"	"1"	"203"	"23.8"	"9.26"	"383.48"	"2.37"	"1"	"1"	"other biological processes"	"nucleus"	"other molecular function"	"Pf11176"	"55319"	"ENSG00000198498"	"TMA16"	"hsa:55319; Q0P6E4; Q0P6J1; Q96EY4; Q9NUR7"	""	""	"0"	"0"	"143.3"	"74.7"	"135.4"	"124.4"	"129.2"	"139.1"	"169.7"	"170.3"	"190.5"	"241.9"	"262.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00170"	"AH receptor-interacting protein OS=Homo sapiens OX=9606 GN=AIP PE=1 SV=2"	"2"	"1"	"2"	"1"	"330"	"37.6"	"6.29"	"237.13"	"2.36"	"1"	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P48681"	"Nestin OS=Homo sapiens OX=9606 GN=NES PE=1 SV=2"	"1"	"1"	"2"	"1"	"1621"	"177.3"	"4.36"	"250.29"	"2.36"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytoskeleton;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00038"	"10763"	"ENSG00000132688"	"NES"	"hsa:10763; O00552; P48681; Q3LIF5; Q5SYZ6"	""	""	"0"	"0"	"47.7"	"35.6"	"59.1"	"47.3"	"55.5"	"49.9"	"61.5"	"69.5"	"120.2"	"164.8"	"217.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15642"	"Cdc42-interacting protein 4 OS=Homo sapiens OX=9606 GN=TRIP10 PE=1 SV=3"	"2"	"1"	"1"	"1"	"601"	"68.3"	"5.73"	""	"2.36"	""	"1"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00018, Pf00611"	"9322"	"ENSG00000125733"	"TRIP10"	"B2R8A6; B7WP22; D6W645; hsa:9322; O15184; Q15642; Q53G22; Q5TZN1; Q6FI24; Q8NFL1; Q8TCY1; Q8TDX3; Q96RJ1"	"Angiopoietin-like protein 8 regulatory pathway"	"Clathrin-mediated endocytosis; RHOQ GTPase cycle"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60315"	"Zinc finger E-box-binding homeobox 2 OS=Homo sapiens OX=9606 GN=ZEB2 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1214"	"136.4"	"6.32"	"283.52"	"2.36"	"1"	"1"	"developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00096, Pf05605, Pf12874"	"9839"	"ENSG00000169554"	"ZEB2"	"A0JP09; B7Z2P2; F5H814; hsa:9839; O60315; Q9UED1"	"Mammary gland development pathway - Embryonic development (Stage 1 of 4); Epithelial to mesenchymal transition in colorectal cancer; TGF-beta receptor signaling in skeletal dysplasias; CCL18 signaling pathway; Extrafollicular and follicular B cell activation by SARS-CoV-2; A network map of Macrophage-stimulating protein (MSP) signaling; TGF-beta receptor signaling"	"Regulation of CDH11 gene transcription"	"8"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96GN5"	"Cell division cycle-associated 7-like protein OS=Homo sapiens OX=9606 GN=CDCA7L PE=1 SV=2"	"2"	"1"	"2"	"1"	"454"	"52.2"	"5.74"	"328.55"	"2.36"	"1"	"1"	"other biological processes"	"cytosol;nucleus"	""	"Pf10497"	"55536"	"ENSG00000164649"	"CDCA7L"	"A4D141; A6NF50; B3KTR5; B4DUT3; C9K0Y1; hsa:55536; Q6PIL4; Q86YT0; Q8IXN5; Q96C70; Q96GN5; Q9H9A2; Q9NPV2"	"Sudden infant death syndrome (SIDS) susceptibility pathways"	""	"1"	"0"	"17.0"	"12.4"	"22.0"	"22.2"	"18.4"	"14.3"	"23.1"	"22.0"	"38.6"	"57.7"	"60.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7RTP6"	"[F-actin]-monooxygenase MICAL3 OS=Homo sapiens OX=9606 GN=MICAL3 PE=1 SV=2"	"1"	"1"	"2"	"1"	"2002"	"224.2"	"5.55"	"262.81"	"2.36"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00412, Pf01494, Pf12130"	"57553"	"ENSG00000243156"	"MICAL3"	"B2RXJ5; E9PEF0; hsa:57553; O94909; Q5U4P4; Q6ICK4; Q7RTP6; Q96DF2; Q9P2I3"	""	""	"0"	"0"	"2.5"	"0.0"	"2.4"	"0.0"	"0.0"	"3.8"	"6.7"	"11.3"	"29.1"	"51.5"	"57.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P33981"	"Dual specificity protein kinase TTK OS=Homo sapiens OX=9606 GN=TTK PE=1 SV=2"	"2"	"1"	"2"	"1"	"857"	"97.0"	"8.16"	"280.33"	"2.36"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"7272"	"ENSG00000112742"	"TTK"	"A8K8U5; B2RDW2; E1P543; hsa:7272; P33981; Q15272; Q5TCS0; Q9BW51; Q9NTM0"	"Cell cycle; Retinoblastoma gene in cancer"	""	"2"	"0"	"23.7"	"27.3"	"26.6"	"27.2"	"31.4"	"26.8"	"27.9"	"45.1"	"86.7"	"173.8"	"235.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22735"	"Protein-glutamine gamma-glutamyltransferase K OS=Homo sapiens OX=9606 GN=TGM1 PE=1 SV=4"	"1"	"1"	"1"	"1"	"817"	"89.7"	"6.04"	""	"2.36"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol"	"other molecular function"	"Pf00868, Pf00927, Pf01841"	"7051"	"ENSG00000092295; ENSG00000285348"	"TGM1"	"B4DWR7; hsa:7051; P22735; Q197M4"	""	"Formation of the cornified envelope"	"1"	"0"	"8.1"	"18.6"	"20.5"	"19.5"	"32.0"	"12.7"	"22.0"	"53.8"	"41.3"	"113.2"	"98.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NRP0"	"Oligosaccharyltransferase complex subunit OSTC OS=Homo sapiens OX=9606 GN=OSTC PE=1 SV=1"	"8"	"1"	"1"	"1"	"149"	"16.8"	"9.13"	""	"2.36"	""	"1"	"protein metabolism;other metabolic processes"	"other membranes;ER/Golgi"	""	"Pf04756"	"58505"	"ENSG00000198856"	"OSTC"	"A8MYS2; B2R5H1; D6RH22; hsa:58505; Q9NRP0; Q9P075; Q9P1R4"	""	""	"0"	"0"	"22.8"	"19.1"	"22.3"	"19.6"	"21.6"	"16.3"	"23.6"	"28.9"	"75.7"	"130.1"	"150.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6XZF7"	"Dynamin-binding protein OS=Homo sapiens OX=9606 GN=DNMBP PE=1 SV=1"	"1"	"1"	"1"	"1"	"1577"	"177.2"	"5.39"	""	"2.35"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;other cell component"	"enzyme regulator activity"	"Pf00018, Pf00621, Pf03114, Pf07653, Pf14604"	"23268"	"ENSG00000107554"	"DNMBP"	"hsa:23268; Q6XZF7; Q8IVY3; Q9Y2L3"	"15q11q13 copy number variation"	"CDC42 GTPase cycle"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"P55039"	"Developmentally-regulated GTP-binding protein 2 OS=Homo sapiens OX=9606 GN=DRG2 PE=1 SV=1"	"3"	"1"	"2"	"1"	"364"	"40.7"	"8.88"	"261.70"	"2.35"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01926, Pf02824, Pf16897"	"1819"	"ENSG00000108591"	"DRG2"	"B2R8G5; hsa:1819; P55039; Q53Y50; Q9BWB2"	"Smith-Magenis and Potocki-Lupski syndrome copy number variation"	""	"1"	"0"	"3.1"	"0.0"	"2.9"	"5.4"	"3.1"	"2.5"	"4.1"	"4.5"	"13.1"	"43.4"	"61.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A6NMY6"	"Putative annexin A2-like protein OS=Homo sapiens OX=9606 GN=ANXA2P2 PE=5 SV=2"	"3"	"1"	"2"	"1"	"339"	"38.6"	"6.95"	"258.77"	"2.35"	"1"	"1"	"transport"	"non-structural extracellular;extracellular matrix;plasma membrane;other membranes;nucleus;other cell component"	"transporter activity;enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00191"	""	""	"ANXA2P2"	"A6NMY6"	""	""	"0"	"0"	"3.2"	"7.4"	"4.1"	"3.7"	"2.9"	"0.0"	"3.2"	"12.0"	"14.2"	"45.7"	"90.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86TB9"	"Protein PAT1 homolog 1 OS=Homo sapiens OX=9606 GN=PATL1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"770"	"86.8"	"6.67"	"307.92"	"2.35"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf09770"	"219988"	"ENSG00000166889"	"PATL1"	"B3KXT9; hsa:219988; Q2TA86; Q6P166; Q86TB9; Q8N9M6; Q8NI63"	""	"mRNA decay by 5' to 3' exoribonuclease"	"1"	"0"	"89.2"	"74.4"	"112.2"	"97.1"	"111.6"	"90.9"	"103.7"	"126.3"	"208.8"	"326.2"	"438.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P031"	"Thyroid transcription factor 1-associated protein 26 OS=Homo sapiens OX=9606 GN=CCDC59 PE=1 SV=2"	"5"	"1"	"2"	"1"	"241"	"28.7"	"9.88"	"294.13"	"2.34"	"1"	"1"	""	"nucleus"	""	"Pf08524"	"29080"	"ENSG00000133773"	"CCDC59"	"hsa:29080; Q9H2V5; Q9NW62; Q9P031"	""	"Surfactant metabolism"	"1"	"0"	"12.5"	"16.3"	"13.3"	"10.9"	"15.7"	"11.1"	"19.2"	"18.3"	"19.3"	"31.2"	"37.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IV48"	"3'-5' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=ERI1 PE=1 SV=3"	"2"	"1"	"2"	"1"	"349"	"40.0"	"6.70"	"309.08"	"2.34"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00929, Pf02037"	"90459"	"ENSG00000104626"	"ERI1"	"A8K4U7; hsa:90459; Q8IV48; Q9NSX3"	"exRNA mechanism of action and biogenesis; 8p23.1 copy number variation syndrome; 4p16.3 copy number variation"	"Major pathway of rRNA processing in the nucleolus and cytosol"	"4"	"0"	"59.9"	"57.9"	"59.3"	"54.3"	"75.4"	"72.3"	"106.7"	"138.5"	"781.0"	"1273.7"	"898.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95363"	"Phenylalanine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=FARS2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"451"	"52.3"	"7.46"	"299.53"	"2.34"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01409, Pf03147"	"10667"	"ENSG00000145982"	"FARS2"	"B2R664; hsa:10667; O95363; Q53F66; Q5TCS3; Q6FG29; Q9NPY7; Q9P062"	""	"Mitochondrial tRNA aminoacylation"	"1"	"0"	"8.6"	"7.4"	"6.7"	"6.2"	"5.4"	"6.4"	"7.2"	"10.1"	"15.1"	"46.7"	"61.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P33527"	"Multidrug resistance-associated protein 1 OS=Homo sapiens OX=9606 GN=ABCC1 PE=1 SV=3"	"1"	"1"	"2"	"1"	"1531"	"171.5"	"7.11"	"315.91"	"2.34"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes"	"transporter activity;other molecular function"	"Pf00005, Pf00664"	"4363"	"ENSG00000103222; ENSG00000278183"	"ABCC1"	"A3RJX2; C9JPJ4; hsa:4363; O14819; O43333; P33527; P78419; Q59GI9; Q9UQ97; Q9UQ99; Q9UQA0"	"Irinotecan pathway; Leukotriene metabolic pathway; TROP2 regulatory signaling"	"ABC-family proteins mediated transport; Paracetamol ADME; Cytoprotection by HMOX1; Transport of RCbl within the body; Heme degradation; Synthesis of Leukotrienes (LT) and Eoxins (EX)"	"9"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"1.9"	"2.4"	"1.3"	"3.1"	"18.4"	"56.7"	"99.6"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BS16"	"Centromere protein K OS=Homo sapiens OX=9606 GN=CENPK PE=1 SV=1"	"4"	"1"	"2"	"1"	"269"	"31.6"	"4.89"	"314.80"	"2.34"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis"	"cytosol;nucleus;other cell component"	""	"Pf11802"	"64105"	"ENSG00000123219"	"CENPK"	"hsa:64105; Q9BS16; Q9H4L0"	""	"Deposition of new CENPA-containing nucleosomes at the centromere; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"7"	"0"	"10.0"	"5.0"	"8.8"	"9.4"	"10.1"	"16.0"	"13.1"	"33.5"	"105.7"	"115.9"	"256.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NRK6"	"ATP-binding cassette sub-family B member 10, mitochondrial OS=Homo sapiens OX=9606 GN=ABCB10 PE=1 SV=2"	"1"	"1"	"2"	"1"	"738"	"79.1"	"9.85"	"299.70"	"2.33"	"1"	"1"	"other metabolic processes;stress response;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00005, Pf00664"	"23456"	"ENSG00000135776"	"ABCB10"	"hsa:23456; Q13040; Q6P1Q8; Q9H3V0; Q9NRK6"	""	"Mitochondrial ABC transporters"	"1"	"0"	"5.5"	"6.8"	"5.8"	"4.3"	"2.1"	"7.6"	"5.7"	"9.6"	"20.4"	"65.7"	"101.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75569"	"Interferon-inducible double-stranded RNA-dependent protein kinase activator A OS=Homo sapiens OX=9606 GN=PRKRA PE=1 SV=1"	"3"	"1"	"2"	"1"	"313"	"34.4"	"8.41"	"249.95"	"2.33"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00035"	"8575"	"ENSG00000180228"	"PRKRA"	"A8K3I6; hsa:8575; O75569; Q53G24; Q6X7T5; Q8NDK4"	"VEGFA-VEGFR2 signaling; Ebola virus infection in host"	"MicroRNA (miRNA) biogenesis; Small interfering RNA (siRNA) biogenesis"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95479"	"GDH/6PGL endoplasmic bifunctional protein OS=Homo sapiens OX=9606 GN=H6PD PE=1 SV=2"	"2"	"1"	"2"	"1"	"791"	"88.8"	"7.30"	"232.19"	"2.33"	"1"	"1"	"other metabolic processes;other biological processes"	"mitochondrion;ER/Golgi"	"other molecular function"	"Pf00479, Pf01182, Pf02781"	"9563"	"ENSG00000049239"	"H6PD"	"hsa:9563; O95479; Q4TT33; Q66I35; Q68DT3; R4GMU1"	"Classical pathway of steroidogenesis with glucocorticoid and mineralocorticoid metabolism"	""	"1"	"0"	"4.0"	"4.1"	"8.5"	"6.8"	"6.3"	"5.5"	"6.3"	"8.3"	"13.7"	"45.9"	"89.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49848"	"Transcription initiation factor TFIID subunit 6 OS=Homo sapiens OX=9606 GN=TAF6 PE=1 SV=1"	"1"	"1"	"2"	"1"	"677"	"72.6"	"8.60"	"251.02"	"2.33"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf02969, Pf07571"	"6878"	"ENSG00000106290"	"TAF6"	"A4D2B2; A4D2B3; B4DT11; D6W5U2; hsa:6878; P49848; Q6AI29"	"Eukaryotic transcription initiation"	"RNA Polymerase II Pre-transcription Events; RNA polymerase II transcribes snRNA genes; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Regulation of TP53 Activity through Phosphorylation"	"11"	"0"	"48.4"	"43.6"	"60.3"	"52.2"	"60.4"	"47.8"	"67.0"	"93.0"	"189.1"	"349.3"	"478.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P10619"	"Lysosomal protective protein OS=Homo sapiens OX=9606 GN=CTSA PE=1 SV=2"	"2"	"1"	"2"	"1"	"480"	"54.4"	"6.61"	"252.78"	"2.33"	"1"	"1"	"protein metabolism;transport;other biological processes"	"non-structural extracellular;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00450"	"5476"	"ENSG00000064601"	"CTSA"	"B2R798; hsa:5476; P10619; Q561W6; Q5JZH1; Q96KJ2; Q9BR08; Q9BW68"	"Ciliary landscape"	"MHC class II antigen presentation; Glycosphingolipid metabolism; Neutrophil degranulation; Sialic acid metabolism; Defective NEU1 causes sialidosis"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IWA0"	"WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1"	"1"	"1"	"2"	"1"	"830"	"94.4"	"5.96"	"294.36"	"2.32"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf00400"	"84128"	"ENSG00000115368"	"WDR75"	"hsa:84128; Q8IWA0; Q96J10; Q9H8U8; Q9H9U5; Q9H9V8; Q9UIX2"	""	"rRNA modification in the nucleus and cytosol; Major pathway of rRNA processing in the nucleolus and cytosol"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BYC9"	"39S ribosomal protein L20, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL20 PE=1 SV=1"	"7"	"1"	"1"	"1"	"149"	"17.4"	"10.86"	""	"2.31"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00453"	"55052"	"ENSG00000242485"	"MRPL20"	"B2RE41; B7Z746; hsa:55052; Q9BYC9"	"1p36 copy number variation syndrome"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86SX6"	"Glutaredoxin-related protein 5, mitochondrial OS=Homo sapiens OX=9606 GN=GLRX5 PE=1 SV=2"	"4"	"1"	"2"	"1"	"157"	"16.6"	"6.79"	"254.66"	"2.31"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00462"	"51218"	"ENSG00000182512"	"GLRX5"	"hsa:51218; Q0X088; Q3YML0; Q86SX6; Q86WY3; Q8IZ54"	"Iron-sulfur cluster biogenesis"	"Mitochondrial iron-sulfur cluster biogenesis"	"2"	"0"	"154.3"	"155.4"	"147.1"	"132.9"	"141.1"	"138.3"	"162.1"	"214.6"	"302.3"	"439.3"	"530.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBB4"	"Ataxin-10 OS=Homo sapiens OX=9606 GN=ATXN10 PE=1 SV=1"	"2"	"1"	"1"	"1"	"475"	"53.5"	"5.25"	""	"2.31"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes"	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf09759"	"25814"	"ENSG00000130638"	"ATXN10"	"A6NLC4; B4DG05; hsa:25814; O14998; O15009; Q6I9X4; Q9UBB4"	"Ciliopathies"	""	"1"	"0"	"5.1"	"3.2"	"5.9"	"4.7"	"5.4"	"7.0"	"4.9"	"10.1"	"20.4"	"40.3"	"84.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P38606"	"V-type proton ATPase catalytic subunit A OS=Homo sapiens OX=9606 GN=ATP6V1A PE=1 SV=2"	"1"	"1"	"2"	"1"	"617"	"68.3"	"5.52"	"347.85"	"2.31"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf00006, Pf02874, Pf16886"	"523"	"ENSG00000114573"	"ATP6V1A"	"B2RBR8; B7Z1R5; D3DN75; hsa:523; P38606; Q53YD9; Q96DY6; Q9UHY3"	"Proximal tubule transport"	"Amino acids regulate mTORC1; ROS and RNS production in phagocytes; Insulin receptor recycling; Transferrin endocytosis and recycling; Ion channel transport"	"6"	"0"	"10.3"	"13.0"	"11.5"	"10.4"	"11.1"	"11.9"	"14.7"	"21.8"	"34.5"	"70.5"	"121.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P54198"	"Protein HIRA OS=Homo sapiens OX=9606 GN=HIRA PE=1 SV=2"	"1"	"1"	"1"	"1"	"1017"	"111.8"	"8.07"	""	"2.30"	""	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00400, Pf07569"	"7290"	"ENSG00000100084"	"HIRA"	"hsa:7290; P54198; Q05BU9; Q8IXN2"	"22q11.2 copy number variation syndrome; 16p11.2 proximal deletion syndrome"	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"	"3"	"0"	"110.7"	"109.3"	"93.8"	"96.9"	"106.0"	"115.2"	"115.3"	"136.8"	"277.5"	"593.0"	"771.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2Q9"	"28S ribosomal protein S28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS28 PE=1 SV=1"	"5"	"1"	"2"	"1"	"187"	"20.8"	"9.10"	"257.38"	"2.30"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	""	"Pf10246"	"28957"	"ENSG00000147586"	"MRPS28"	"B2RDZ7; hsa:28957; Q96Q21; Q9Y2Q9"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96QK1"	"Vacuolar protein sorting-associated protein 35 OS=Homo sapiens OX=9606 GN=VPS35 PE=1 SV=2"	"1"	"1"	"1"	"1"	"796"	"91.6"	"5.49"	""	"2.30"	""	"1"	"cell-cell signaling;cell organization and biogenesis;transport;signal transduction;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding"	"Pf03635"	"55737"	"ENSG00000069329"	"VPS35"	"hsa:55737; Q561W2; Q96QK1; Q9H016; Q9H096; Q9H4P3; Q9H8J0; Q9NRS7; Q9NVG2; Q9NX80; Q9NZK2"	""	"WNT ligand biogenesis and trafficking"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P2N2"	"Rho GTPase-activating protein 28 OS=Homo sapiens OX=9606 GN=ARHGAP28 PE=1 SV=3"	"1"	"1"	"2"	"1"	"729"	"82.0"	"7.75"	"259.44"	"2.29"	"1"	"1"	"cell organization and biogenesis;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf00620"	""	"ENSG00000088756"	"ARHGAP28"	"A8MQB7; A8MU88; Q6P160; Q8N4T3; Q9NW53; Q9P2N2"	""	"RHOA GTPase cycle"	"1"	"0"	"10.5"	"10.7"	"10.9"	"7.6"	"11.4"	"10.7"	"10.2"	"13.7"	"43.7"	"66.2"	"70.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q05655"	"Protein kinase C delta type OS=Homo sapiens OX=9606 GN=PRKCD PE=1 SV=2"	"2"	"1"	"2"	"1"	"676"	"77.5"	"7.75"	"276.02"	"2.29"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069, Pf00130, Pf00433"	"5580"	"ENSG00000163932"	"PRKCD"	"B0KZ81; B2R834; hsa:5580; Q05655; Q15144; Q86XJ6"	"Type II diabetes mellitus; Glioblastoma signaling pathways; B cell receptor signaling pathway; AGE/RAGE pathway; Corticotropin-releasing hormone signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Alpha 6 beta 4 signaling pathway; Myometrial relaxation and contraction pathways; G protein signaling pathways; IL6 signaling pathway; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Wnt signaling pathway and pluripotency; Pancreatic adenocarcinoma pathway; Non-genomic actions of 1,25 dihydroxyvitamin D3; EGF/EGFR signaling pathway; Hippo signaling regulation pathways; Translation inhibitors in chronically activated PDGFRA cells; Gastrin signaling pathway; IL-18 signaling pathway; Osteoblast differentiation and related diseases; Insulin signaling; Kisspeptin/kisspeptin receptor system in the ovary; Galanin receptor pathway; Orexin receptor pathway; CCL18 signaling pathway; Chronic hyperglycemia impairment of neuron function; TROP2 regulatory signaling; Calcium regulation in cardiac cells; Type II interferon signaling; T-cell receptor signaling pathway"	"CLEC7A (Dectin-1) signaling; KEAP1-NFE2L2 pathway; Neutrophil degranulation; Interferon gamma signaling; Role of phospholipids in phagocytosis; G alpha (z) signalling events; SHC1 events in ERBB2 signaling; HuR (ELAVL1) binds and stabilizes mRNA; VEGFR2 mediated cell proliferation; DAG and IP3 signaling; Effects of PIP2 hydrolysis; RHO GTPases Activate NADPH Oxidases; Calmodulin induced events; Apoptotic cleavage of cellular proteins"	"47"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P57772"	"Selenocysteine-specific elongation factor OS=Homo sapiens OX=9606 GN=EEFSEC PE=1 SV=4"	"1"	"1"	"2"	"1"	"596"	"65.3"	"8.35"	"239.06"	"2.29"	"1"	"1"	"protein metabolism;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009"	"60678"	"ENSG00000132394; ENSG00000284869"	"EEFSEC"	"hsa:60678; P57772; Q96HZ6"	""	"Selenocysteine synthesis"	"1"	"0"	"115.0"	"92.9"	"127.7"	"109.6"	"119.8"	"136.6"	"214.6"	"398.9"	"437.3"	"371.9"	"371.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P17028"	"Zinc finger protein 24 OS=Homo sapiens OX=9606 GN=ZNF24 PE=1 SV=4"	"2"	"1"	"1"	"1"	"368"	"42.1"	"6.21"	""	"2.29"	""	"1"	"developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00096, Pf02023"	"7572"	"ENSG00000172466"	"ZNF24"	"hsa:7572; O14754; P17028; Q53YE4; Q6ICR5; Q8IZN4"	""	""	"0"	"0"	"243.7"	"202.7"	"236.5"	"211.8"	"210.7"	"224.0"	"279.5"	"288.0"	"376.6"	"554.6"	"698.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13510"	"Acid ceramidase OS=Homo sapiens OX=9606 GN=ASAH1 PE=1 SV=5"	"3"	"1"	"1"	"1"	"395"	"44.6"	"7.62"	""	"2.28"	""	"1"	"other metabolic processes;other biological processes"	"non-structural extracellular;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf02275, Pf15508"	"427"	"ENSG00000104763"	"ASAH1"	"E9PDS0; hsa:427; Q13510; Q6W898; Q96AS2"	"Sphingolipid pathway; S1P receptor signal transduction; Sphingolipid metabolism: integrated pathway; Sphingolipid metabolism in senescence; Biosynthesis and turnover of 1-deoxy-sphingoid bases; Synthesis of ceramides and 1-deoxyceramides"	"Glycosphingolipid metabolism; Neutrophil degranulation"	"8"	"0"	"21.8"	"26.4"	"19.5"	"21.2"	"31.2"	"26.0"	"25.5"	"35.0"	"37.4"	"72.2"	"78.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NCM8"	"Cytoplasmic dynein 2 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC2H1 PE=1 SV=4"	"0"	"1"	"1"	"1"	"4307"	"492.3"	"6.54"	""	"2.28"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03028, Pf08385, Pf08393, Pf12774, Pf12775, Pf12777, Pf12780, Pf12781, Pf18198, Pf18199"	"79659"	"ENSG00000187240"	"DYNC2H1"	"hsa:79659; O00432; Q16693; Q3C1U8; Q4AC93; Q6ZMX7; Q6ZUM6; Q7Z363; Q8N977; Q8NCM8; Q92815; Q9HAE4"	"Intraflagellar transport proteins binding to dynein; Genes related to primary cilium development (based on CRISPR); Ciliopathies; 3q29 copy number variation syndrome; Bardet-Biedl syndrome"	"Hedgehog 'off' state; Intraflagellar transport"	"7"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60244"	"Mediator of RNA polymerase II transcription subunit 14 OS=Homo sapiens OX=9606 GN=MED14 PE=1 SV=2"	"0"	"1"	"2"	"1"	"1454"	"160.5"	"8.73"	"236.04"	"2.28"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf08638"	"9282"	"ENSG00000180182"	"MED14"	"hsa:9282; O60244; Q4KMR7; Q9UNB3"	"Vitamin D in inflammatory diseases"	"PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; Generic Transcription Pathway"	"4"	"0"	"42.6"	"52.3"	"52.3"	"44.8"	"57.8"	"50.9"	"55.2"	"60.7"	"91.9"	"123.5"	"167.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4D1"	"Disheveled-associated activator of morphogenesis 1 OS=Homo sapiens OX=9606 GN=DAAM1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1078"	"123.4"	"7.23"	"284.07"	"2.28"	"1"	"1"	"cell-cell signaling;cell organization and biogenesis;signal transduction"	"plasma membrane;other membranes;cytosol;cytoskeleton"	"cytoskeletal activity;other molecular function"	"Pf02181, Pf06367, Pf06371"	"23002"	"ENSG00000100592"	"DAAM1"	"hsa:23002; Q86U34; Q8N1Z8; Q8TB39; Q9Y4D1"	"Physico-chemical features and toxicity-associated pathways; Wnt signaling"	"RHO GTPases Activate Formins; PCP/CE pathway; CDC42 GTPase cycle; RHOC GTPase cycle; RHOA GTPase cycle; RHOB GTPase cycle"	"8"	"0"	"45.5"	"38.9"	"54.4"	"43.7"	"58.4"	"48.8"	"63.0"	"71.6"	"161.8"	"347.1"	"412.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00411"	"DNA-directed RNA polymerase, mitochondrial OS=Homo sapiens OX=9606 GN=POLRMT PE=1 SV=2"	"0"	"1"	"1"	"1"	"1230"	"138.5"	"8.98"	""	"2.28"	""	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00940, Pf14700"	"5442"	"ENSG00000099821"	"POLRMT"	"hsa:5442; O00411; O60370"	"Mitochondrial gene expression"	"Mitochondrial transcription initiation; Transcriptional activation of mitochondrial biogenesis"	"3"	"0"	"65.3"	"70.6"	"73.3"	"66.5"	"66.4"	"43.9"	"83.5"	"128.8"	"181.8"	"338.4"	"496.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IXW5"	"Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 OS=Homo sapiens OX=9606 GN=RPAP2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"612"	"69.5"	"7.78"	"282.66"	"2.28"	"1"	"1"	"RNA metabolism OR transcription;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf04181"	"79871"	"ENSG00000122484"	"RPAP2"	"C9JKB5; hsa:79871; Q49AS7; Q8IXW5; Q9H8Y2"	""	"RNA polymerase II transcribes snRNA genes"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q06033"	"Inter-alpha-trypsin inhibitor heavy chain H3 OS=Homo sapiens OX=9606 GN=ITIH3 PE=1 SV=2"	"1"	"1"	"1"	"1"	"890"	"99.8"	"5.74"	""	"2.28"	""	"1"	"other metabolic processes;other biological processes"	"non-structural extracellular;other cell component"	"enzyme regulator activity"	"Pf00092, Pf06668, Pf08487"	"3699"	"ENSG00000162267"	"ITIH3"	"hsa:3699; Q06033; Q3B7H5; Q53F06; Q6LAM2; Q99085"	"Network map of SARS-CoV-2 signaling pathway"	"Platelet degranulation"	"2"	"0"	"73.0"	"33.5"	"130.7"	"94.3"	"120.0"	"103.7"	"100.0"	"84.0"	"160.0"	"406.9"	"525.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2L9"	"Leucine-rich repeat and calponin homology domain-containing protein 1 OS=Homo sapiens OX=9606 GN=LRCH1 PE=1 SV=3"	"1"	"1"	"2"	"1"	"728"	"80.8"	"5.94"	"301.85"	"2.28"	"1"	"1"	"other biological processes"	"other cell component"	""	"Pf00307, Pf13855"	"23143"	"ENSG00000136141"	"LRCH1"	"B7ZLL5; F8W6F0; hsa:23143; Q17R43; Q2KHR1; Q5TBU9; Q7Z5F6; Q7Z5F7; Q9Y2L9"	""	""	"0"	"0"	"23.8"	"25.2"	"32.1"	"25.5"	"36.1"	"23.7"	"44.6"	"52.1"	"112.6"	"303.3"	"401.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q562F6"	"Shugoshin 2 OS=Homo sapiens OX=9606 GN=SGO2 PE=1 SV=2"	"1"	"2"	"2"	"1"	"1265"	"144.7"	"7.91"	"243.37"	"2.27"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	""	""	"151246"	"ENSG00000163535"	"SGO2"	"hsa:151246; Q53RR9; Q53T20; Q562F6; Q86XY4; Q8IWK2; Q8IZK1; Q8N1Q5; Q96LQ3"	"Cohesin complex - Cornelia de Lange syndrome"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"7"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96L92"	"Sorting nexin-27 OS=Homo sapiens OX=9606 GN=SNX27 PE=1 SV=2"	"2"	"1"	"2"	"1"	"541"	"61.2"	"6.49"	"303.85"	"2.27"	"1"	"1"	"transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00595, Pf00787, Pf00788"	"81609"	"ENSG00000143376"	"SNX27"	"hsa:81609; Q32Q36; Q4AEJ5; Q5VWB0; Q5VWB1; Q5VWB2; Q6IPP6; Q86UB1; Q96D79; Q96L92; Q9H3K8"	""	""	"0"	"0"	"28.8"	"19.9"	"32.0"	"25.4"	"30.4"	"27.1"	"32.8"	"45.8"	"179.4"	"402.2"	"635.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5T1V6"	"Probable ATP-dependent RNA helicase DDX59 OS=Homo sapiens OX=9606 GN=DDX59 PE=1 SV=1"	"2"	"1"	"2"	"1"	"619"	"68.8"	"7.44"	"272.79"	"2.27"	"1"	"1"	""	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04438"	"83479"	"ENSG00000118197"	"DDX59"	"hsa:83479; Q5T1V6; Q6PJL2; Q8IVW3; Q9H0W3"	"Ciliopathies"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60174"	"Triosephosphate isomerase OS=Homo sapiens OX=9606 GN=TPI1 PE=1 SV=3"	"5"	"1"	"1"	"1"	"286"	"30.8"	"5.92"	""	"2.27"	""	"1"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf00121"	""	"ENSPPYG00000004207; ENSPTRG00000004595"	"TPI1"	"A0A2J8JEI5; A0A2J8JEJ3; A0A2J8TBG7; A0A6D2X563; H2NGA4"	""	""	"0"	"0"	"105.9"	"59.1"	"154.6"	"121.8"	"125.5"	"134.7"	"145.2"	"150.4"	"288.6"	"622.6"	"1099.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BWD1"	"Acetyl-CoA acetyltransferase, cytosolic OS=Homo sapiens OX=9606 GN=ACAT2 PE=1 SV=2"	"3"	"1"	"2"	"1"	"397"	"41.3"	"6.92"	"377.82"	"2.26"	"1"	"1"	"other metabolic processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00108, Pf02803"	"39"	"ENSG00000120437"	"ACAT2"	"B7Z233; E1P5B1; hsa:39; Q16146; Q5TCL7; Q8TDM4; Q9BWD1"	"Mevalonate pathway; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Cholesterol metabolism; Cholesterol biosynthesis pathway in hepatocytes; Enterocyte cholesterol metabolism"	"Cholesterol biosynthesis"	"6"	"0"	"15.3"	"27.5"	"15.8"	"16.9"	"12.2"	"11.2"	"16.0"	"22.6"	"32.1"	"56.4"	"76.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N9R8"	"Protein SCAI OS=Homo sapiens OX=9606 GN=SCAI PE=1 SV=2"	"2"	"1"	"2"	"1"	"606"	"70.4"	"8.60"	"265.54"	"2.26"	"1"	"1"	"other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf12070"	"286205"	"ENSG00000173611"	"SCAI"	"hsa:286205; Q3SXZ1; Q3SXZ2; Q5T163; Q8N1I4; Q8N9R8"	""	"RHO GTPases Activate Formins"	"1"	"0"	"6.8"	"6.2"	"5.5"	"8.3"	"10.3"	"6.8"	"9.4"	"7.0"	"9.4"	"16.9"	"29.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IXH7"	"Negative elongation factor C/D OS=Homo sapiens OX=9606 GN=NELFCD PE=1 SV=2"	"2"	"1"	"2"	"1"	"590"	"66.2"	"5.10"	"316.41"	"2.26"	"1"	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf04858"	"51497"	"ENSG00000101158"	"NELFCD"	"B4DE06; hsa:51497; Q8IXH7; Q9BYL2; Q9H405; Q9H888; Q9H8T3; Q9NVX5; Q9P029; Q9UGN1; Q9UGN2; Q9UGN3"	"Initiation of transcription and translation elongation at the HIV-1 LTR; 4p16.3 copy number variation"	"RNA Polymerase II Pre-transcription Events; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; TP53 Regulates Transcription of DNA Repair Genes"	"16"	"0"	"9.3"	"6.2"	"10.0"	"10.9"	"12.7"	"8.2"	"11.3"	"17.8"	"52.2"	"86.1"	"106.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96GM5"	"SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 OS=Homo sapiens OX=9606 GN=SMARCD1 PE=1 SV=2"	"5"	"2"	"3"	"2"	"515"	"58.2"	"9.25"	"618.86"	"2.25"	"2"	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf02201"	"6602"	"ENSG00000066117"	"SMARCD1"	"A6NN27; hsa:6602; Q92924; Q96GM5; Q9Y635"	"Androgen receptor network in prostate cancer; Tumor suppressor activity of SMARCB1; Thermogenesis; Kleefstra syndrome"	"RMTs methylate histone arginines; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"	"6"	"0"	"186.9"	"153.3"	"184.7"	"149.5"	"182.8"	"190.4"	"214.9"	"248.6"	"413.6"	"907.0"	"1279.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96P70"	"Importin-9 OS=Homo sapiens OX=9606 GN=IPO9 PE=1 SV=3"	"1"	"1"	"2"	"1"	"1041"	"115.9"	"4.81"	"263.12"	"2.25"	"1"	"1"	"transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf03810"	"55705"	"ENSG00000198700"	"IPO9"	"B1ASV5; hsa:55705; Q8N1Y1; Q8N3I2; Q8NCG9; Q96P70; Q96SU6; Q9NW01; Q9P0A8; Q9ULM8"	""	""	"0"	"0"	"5.0"	"3.0"	"8.1"	"4.3"	"3.2"	"6.9"	"7.4"	"8.1"	"16.9"	"36.5"	"35.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O76041"	"Nebulette OS=Homo sapiens OX=9606 GN=NEBL PE=1 SV=1"	"2"	"1"	"2"	"1"	"1014"	"116.4"	"7.99"	""	"2.24"	""	"1"	"cell organization and biogenesis;developmental processes"	"cytoskeleton"	"cytoskeletal activity;other molecular function"	"Pf00880, Pf14604, Pf17705"	"10529"	"ENSG00000078114"	"NEBL"	"B0YJ45; B9EIM9; E9PRX7; hsa:10529; O76041; Q2TBD0; Q5VZT2; Q70I54; Q9UIC4"	""	""	"0"	"0"	"48.4"	"32.9"	"44.0"	"41.5"	"39.7"	"32.5"	"46.7"	"61.8"	"322.6"	"814.6"	"1242.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P48201"	"ATP synthase F(0) complex subunit C3, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5MC3 PE=1 SV=1"	"5"	"1"	"2"	"1"	"142"	"14.7"	"9.45"	"310.54"	"2.24"	"1"	"1"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00137"	"518"	"ENSG00000154518"	"ATP5MC3"	"B2R4Z0; D3DPF0; hsa:518; P48201; Q4ZFX7"	"Electron transport chain: OXPHOS system in mitochondria; 7q11.23 copy number variation syndrome; Oxidative phosphorylation"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"5"	"0"	"125.8"	"124.9"	"112.6"	"114.9"	"148.9"	"193.8"	"250.8"	"383.2"	"464.5"	"736.7"	"1085.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49450"	"Histone H3-like centromeric protein A OS=Homo sapiens OX=9606 GN=CENPA PE=1 SV=1"	"4"	"1"	"1"	"1"	"140"	"16.0"	"11.71"	""	"2.24"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125"	"1058"	"ENSG00000115163"	"CENPA"	"D6W544; hsa:1058; P49450; Q53T74; Q9BVW2"	"2q37 copy number variation syndrome"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Deposition of new CENPA-containing nucleosomes at the centromere; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"8"	"0"	"52.2"	"40.1"	"47.4"	"47.2"	"53.5"	"43.1"	"51.3"	"56.1"	"130.8"	"334.8"	"408.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55198"	"Protein AF-17 OS=Homo sapiens OX=9606 GN=MLLT6 PE=1 SV=3"	"1"	"1"	"2"	"1"	"1093"	"112.0"	"8.62"	"238.01"	"2.24"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"nucleus"	"other molecular function"	"Pf00628, Pf13832"	"4302"	"ENSG00000275023; ENSG00000275851"	"MLLT6"	"hsa:4302; P55198; Q59F28; Q96IU3; Q9H5F6; Q9UF49"	"17q12 copy number variation syndrome"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P57678"	"Gem-associated protein 4 OS=Homo sapiens OX=9606 GN=GEMIN4 PE=1 SV=2"	"1"	"1"	"1"	"1"	"1058"	"120.0"	"6.04"	""	"2.24"	""	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	""	"50628"	"ENSG00000179409"	"GEMIN4"	"hsa:50628; P57678; Q9NZS7; Q9UG32; Q9Y4Q2"	""	"SARS-CoV-2 modulates host translation machinery; snRNP Assembly"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50402"	"Emerin OS=Homo sapiens OX=9606 GN=EMD PE=1 SV=1"	"7"	"2"	"3"	"2"	"254"	"29.0"	"5.50"	"752.43"	"2.24"	"2"	"1"	"cell organization and biogenesis;other biological processes"	"other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity"	"Pf03020"	"2010"	"ENSG00000102119"	"EMD"	"hsa:2010; P50402; Q6FI02"	"Arrhythmogenic right ventricular cardiomyopathy; Envelope proteins and their potential roles in EDMD physiopathology; Influence of laminopathies on Wnt signaling"	"Initiation of Nuclear Envelope (NE) Reformation; Depolymerization of the Nuclear Lamina; RHOG GTPase cycle; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOD GTPase cycle; Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"	"12"	"0"	"149.1"	"148.5"	"146.8"	"127.8"	"147.9"	"145.6"	"189.7"	"215.5"	"352.7"	"636.7"	"891.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2R5"	"28S ribosomal protein S17, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS17 PE=1 SV=1"	"8"	"1"	"1"	"1"	"130"	"14.5"	"9.85"	""	"2.24"	""	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity"	"Pf00366"	"51373"	"ENSG00000239789"	"MRPS17"	"hsa:51373; Q86X15; Q9Y2R5"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"27.4"	"25.3"	"36.9"	"33.0"	"38.5"	"34.4"	"37.9"	"42.7"	"76.0"	"119.3"	"141.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9ULR3"	"Protein phosphatase 1H OS=Homo sapiens OX=9606 GN=PPM1H PE=1 SV=2"	"2"	"1"	"2"	"1"	"514"	"56.4"	"6.60"	"280.99"	"2.24"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00481"	"57460"	"ENSG00000111110"	"PPM1H"	"B1Q2A9; B2RXG4; hsa:57460; Q6PI86; Q9ULR3"	""	""	"0"	"0"	"4.2"	"5.0"	"5.0"	"3.3"	"4.2"	"2.7"	"2.6"	"5.0"	"18.2"	"63.6"	"102.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92794"	"Histone acetyltransferase KAT6A OS=Homo sapiens OX=9606 GN=KAT6A PE=1 SV=2"	"1"	"1"	"2"	"1"	"2004"	"224.9"	"5.68"	"281.30"	"2.24"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00628, Pf01853, Pf17772"	"7994"	"ENSG00000083168"	"KAT6A"	"hsa:7994; Q76L81; Q92794"	"Pathways affected in adenoid cystic carcinoma"	"HATs acetylate histones; Regulation of TP53 Activity through Acetylation"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15254"	"Peroxisomal acyl-coenzyme A oxidase 3 OS=Homo sapiens OX=9606 GN=ACOX3 PE=1 SV=2"	"2"	"1"	"1"	"1"	"700"	"77.6"	"7.25"	""	"2.24"	""	"1"	"other metabolic processes;other biological processes"	"cytosol;other cytoplasmic organelle"	"other molecular function"	"Pf01756, Pf02770"	"8310"	"ENSG00000087008"	"ACOX3"	"hsa:8310; O15254; Q96AJ8"	"PPAR signaling pathway; Eicosanoid metabolism via cyclooxygenases (COX); Eicosanoid metabolism via lipooxygenases (LOX); Omega-3 / omega-6 fatty acid synthesis"	"Peroxisomal protein import; Beta-oxidation of pristanoyl-CoA"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3D0"	"Cytosolic iron-sulfur assembly component 2B OS=Homo sapiens OX=9606 GN=CIAO2B PE=1 SV=1"	"4"	"1"	"1"	"1"	"163"	"17.7"	"5.19"	""	"2.23"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;cytoskeleton;nucleus;other cell component"	""	"Pf01883"	"51647"	"ENSG00000166595"	"CIAO2B"	"hsa:51647; Q9Y3D0"	"Iron-sulfur cluster biogenesis; 2q11.2 copy number variation syndrome"	"Cytosolic iron-sulfur cluster assembly"	"3"	"0"	"45.1"	"46.5"	"59.6"	"45.8"	"50.0"	"51.6"	"65.1"	"75.3"	"151.0"	"258.3"	"335.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6IWH7"	"Anoctamin-7 OS=Homo sapiens OX=9606 GN=ANO7 PE=1 SV=2"	"2"	"1"	"1"	"1"	"933"	"105.5"	"7.87"	""	"2.23"	""	"1"	"cell organization and biogenesis;transport"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"transporter activity;other molecular function"	"Pf04547, Pf16178"	"50636"	"ENSG00000146205"	"ANO7"	"hsa:50636; Q6IWH6; Q6IWH7"	"2q37 copy number variation syndrome"	"Stimuli-sensing channels; Induction of Cell-Cell Fusion"	"3"	"0"	"119.8"	"57.7"	"155.9"	"79.9"	"106.1"	"102.9"	"120.1"	"84.8"	"132.5"	"157.2"	"241.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P40818"	"Ubiquitin carboxyl-terminal hydrolase 8 OS=Homo sapiens OX=9606 GN=USP8 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1118"	"127.4"	"8.51"	"312.97"	"2.23"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00443, Pf00581, Pf08969"	"9101"	"ENSG00000138592"	"USP8"	"B4DKA8; hsa:9101; P40818; Q2TB31; Q7Z3U2; Q86VA0; Q8IWI7"	"EGF/EGFR signaling pathway; Male infertility"	"Ub-specific processing proteases; Negative regulation of MET activity; Downregulation of ERBB2:ERBB3 signaling; Regulation of FZD by ubiquitination"	"6"	"0"	"53.5"	"49.0"	"52.2"	"45.6"	"47.9"	"57.2"	"69.9"	"73.5"	"139.0"	"233.9"	"331.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q71RC2"	"La-related protein 4 OS=Homo sapiens OX=9606 GN=LARP4 PE=1 SV=3"	"3"	"2"	"3"	"2"	"724"	"80.5"	"6.61"	"882.31"	"2.23"	"2"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity"	"Pf05383"	"113251"	"ENSG00000161813"	"LARP4"	"A8K6T1; E9PDG5; G3XAA8; G5E976; hsa:113251; Q5CZ97; Q6ZV14; Q71RC2; Q96NF9"	""	""	"0"	"0"	"97.0"	"104.3"	"104.8"	"86.6"	"118.4"	"110.8"	"134.5"	"171.5"	"187.2"	"245.5"	"290.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61081"	"NEDD8-conjugating enzyme Ubc12 OS=Homo sapiens OX=9606 GN=UBE2M PE=1 SV=1"	"10"	"2"	"3"	"2"	"183"	"20.9"	"7.69"	"535.73"	"2.23"	"2"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00179"	"9040"	"ENSG00000130725"	"UBE2M"	"hsa:9040; O76069; P61081; Q8VC50"	""	"Antigen processing: Ubiquitination & Proteasome degradation; Dectin-1 mediated noncanonical NF-kB signaling; NIK-->noncanonical NF-kB signaling; Neddylation; TGF-beta receptor signaling activates SMADs"	"5"	"0"	"70.2"	"55.4"	"93.4"	"72.9"	"80.4"	"81.6"	"89.3"	"128.9"	"245.9"	"578.0"	"1408.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A6NEE1"	"Pleckstrin homology domain-containing family D member 1 OS=Homo sapiens OX=9606 GN=PLEKHD1 PE=2 SV=3"	"2"	"1"	"1"	"1"	"506"	"59.2"	"6.44"	""	"2.23"	""	"1"	""	""	""	"Pf00169"	"400224"	"ENSG00000175985"	"PLEKHD1"	"A6NEE1; B9EJC2; hsa:400224"	""	""	"0"	"0"	"81.1"	"81.6"	"97.0"	"73.7"	"101.9"	"93.1"	"97.9"	"111.1"	"150.9"	"202.8"	"237.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96MN5"	"Transcription elongation factor A N-terminal and central domain-containing protein 2 OS=Homo sapiens OX=9606 GN=TCEANC2 PE=1 SV=1"	"5"	"1"	"2"	"1"	"208"	"24.1"	"10.05"	"315.69"	"2.23"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf08711"	"127428"	"ENSG00000116205"	"TCEANC2"	"hsa:127428; Q5T702; Q8N8N2; Q96MN5"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95835"	"Serine/threonine-protein kinase LATS1 OS=Homo sapiens OX=9606 GN=LATS1 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1130"	"126.8"	"8.70"	"296.45"	"2.22"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00627"	"9113"	"ENSG00000131023"	"LATS1"	"hsa:9113; O95835; Q6PKD0"	"Mesodermal commitment pathway; Transcription co-factors SKI and SKIL protein partners; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-YAP signaling; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; Leukocyte-intrinsic Hippo pathway functions; Pleural mesothelioma"	"Signaling by Hippo"	"9"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A6NED2"	"RCC1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RCCD1 PE=1 SV=1"	"3"	"1"	"1"	"1"	"376"	"40.1"	"5.27"	""	"2.22"	""	"1"	"cell organization and biogenesis"	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf00415"	"91433"	"ENSG00000166965"	"RCCD1"	"A6NED2; B2RTP9; hsa:91433; Q29RX6"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60566"	"Mitotic checkpoint serine/threonine-protein kinase BUB1 beta OS=Homo sapiens OX=9606 GN=BUB1B PE=1 SV=3"	"2"	"1"	"1"	"1"	"1050"	"119.5"	"5.27"	""	"2.22"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf08311"	"701"	"ENSG00000156970"	"BUB1B"	"B2R6U0; B4DL09; B4DLG3; hsa:701; O60501; O60566; O60627; O60758; O75389; Q59HH6; Q8WV50; Q96KM4"	"Regulation of sister chromatid separation at the metaphase-anaphase transition; 10q22q23 copy number variation"	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of mitotic proteins; APC-Cdc20 mediated degradation of Nek2A"	"12"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQE4"	"Selenoprotein S OS=Homo sapiens OX=9606 GN=SELENOS PE=1 SV=3"	"6"	"1"	"2"	"1"	"189"	"21.2"	"9.70"	"246.66"	"2.22"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytoskeleton;ER/Golgi"	"other molecular function"	"Pf06936"	"55829"	"ENSG00000131871"	"SELENOS"	"hsa:55829; Q3B771; Q9BQE4; Q9P0I6"	"Selenium micronutrient network"	"E3 ubiquitin ligases ubiquitinate target proteins"	"2"	"0"	"3.6"	"2.4"	"8.0"	"6.6"	"5.2"	"6.2"	"8.7"	"8.7"	"23.4"	"36.2"	"51.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NAN2"	"Mitoguardin 1 OS=Homo sapiens OX=9606 GN=MIGA1 PE=1 SV=1"	"3"	"1"	"1"	"1"	"632"	"71.0"	"5.63"	""	"2.21"	""	"1"	"cell organization and biogenesis"	"plasma membrane;other membranes;mitochondrion"	"other molecular function"	"Pf10265"	"374986"	"ENSG00000180488"	"MIGA1"	"hsa:374986; Q6MZG0; Q8NAN2"	""	"Synthesis of PA"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P42695"	"Condensin-2 complex subunit D3 OS=Homo sapiens OX=9606 GN=NCAPD3 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1498"	"168.8"	"7.50"	"255.11"	"2.21"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf12717"	"23310"	"ENSG00000151503"	"NCAPD3"	"A6NFS2; hsa:23310; P42695; Q4KMQ9"	""	"Condensation of Prophase Chromosomes"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IU60"	"m7GpppN-mRNA hydrolase OS=Homo sapiens OX=9606 GN=DCP2 PE=1 SV=3"	"1"	"1"	"1"	"1"	"420"	"48.4"	"8.00"	""	"2.20"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00293, Pf05026"	"167227"	"ENSG00000172795"	"DCP2"	"C9J778; hsa:167227; Q6P2D4; Q7Z5W5; Q8IU60; Q8NBG5"	""	"mRNA decay by 5' to 3' exoribonuclease; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"	"5"	"0"	"93.6"	"100.9"	"75.8"	"79.9"	"91.5"	"76.7"	"92.0"	"124.5"	"197.6"	"281.8"	"341.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15439"	"Multidrug resistance-associated protein 4 OS=Homo sapiens OX=9606 GN=ABCC4 PE=1 SV=3"	"1"	"1"	"2"	"1"	"1325"	"149.4"	"8.19"	"318.58"	"2.20"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport"	"plasma membrane;other membranes;ER/Golgi;nucleus"	"transporter activity;other molecular function"	"Pf00005, Pf00664"	"10257"	"ENSG00000125257"	"ABCC4"	"A9Z1Z7; B7Z3Q7; hsa:10257; O15439; Q8IVZ4; Q8IZN6; Q8NEW8; Q9Y6J2"	"Fluoropyrimidine activity; Androgen receptor network in prostate cancer; Drug induction of bile acid pathway; Ectoderm differentiation; Pregnane X receptor pathway; Nuclear receptors meta-pathway; NRF2 pathway; Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling; TYROBP causal network in microglia; Aspirin and miRNAs; Proximal tubule transport; FOXA2 pathway; Prostaglandin synthesis and regulation"	"ABC-family proteins mediated transport; Paracetamol ADME; Platelet degranulation ; Azathioprine ADME"	"17"	"0"	"3.6"	"4.1"	"5.1"	"3.1"	"2.8"	"3.9"	"5.8"	"6.5"	"48.5"	"59.2"	"56.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9GZS3"	"WD repeat-containing protein 61 OS=Homo sapiens OX=9606 GN=WDR61 PE=1 SV=1"	"2"	"1"	"1"	"1"	"305"	"33.6"	"5.47"	""	"2.20"	""	"1"	"cell-cell signaling;protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf00400"	"80349"	"ENSG00000140395"	"SKIC8"	"D3DW84; hsa:80349; Q6IA22; Q7Z4X4; Q9GZS3"	""	"Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events; E3 ubiquitin ligases ubiquitinate target proteins; mRNA decay by 3' to 5' exoribonuclease"	"5"	"0"	"145.2"	"128.0"	"145.1"	"112.7"	"136.6"	"134.0"	"152.2"	"186.1"	"321.7"	"684.1"	"1026.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51587"	"Breast cancer type 2 susceptibility protein OS=Homo sapiens OX=9606 GN=BRCA2 PE=1 SV=3"	"0"	"1"	"2"	"1"	"3418"	"384.0"	"6.71"	"264.99"	"2.19"	"1"	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H4B0"	"Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OSGEPL1 PE=2 SV=2"	"1"	"1"	"1"	"1"	"414"	"45.1"	"8.56"	""	"2.19"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00814"	"64172"	"ENSG00000128694"	"OSGEPL1"	"hsa:64172; Q96EV9; Q96NH5; Q9H4B0"	""	""	"0"	"0"	"40.4"	"35.6"	"45.1"	"33.8"	"41.7"	"37.3"	"74.0"	"149.3"	"376.2"	"548.8"	"493.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P15927"	"Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2 PE=1 SV=1"	"2"	"1"	"1"	"1"	"270"	"29.2"	"6.15"	""	"2.19"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf08784"	"6118"	"ENSG00000117748"	"RPA2"	"hsa:6118; P15927; Q52II0; Q5TEI9; Q5TEJ5"	"miRNA regulation of DNA damage response; Retinoblastoma gene in cancer; G1 to S cell cycle control; DNA replication; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair; DNA damage response"	"Regulation of HSF1-mediated heat shock response; Fanconi Anemia Pathway; Regulation of TP53 Activity through Phosphorylation; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Meiotic recombination; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; HSF1 activation; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Removal of the Flap Intermediate; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"38"	"0"	"162.8"	"152.5"	"175.8"	"151.5"	"161.9"	"145.6"	"178.3"	"241.3"	"328.3"	"490.3"	"926.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UG01"	"Intraflagellar transport protein 172 homolog OS=Homo sapiens OX=9606 GN=IFT172 PE=1 SV=2"	"1"	"1"	"1"	"1"	"1749"	"197.5"	"6.13"	""	"2.19"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"cytoskeleton;other cell component"	""	"Pf00400"	"26160"	"ENSG00000138002"	"IFT172"	"A5PKZ0; B2RNU5; hsa:26160; Q86X44; Q96HW4; Q9UFJ9; Q9UG01; Q9ULP1"	"Ciliary landscape; Genes related to primary cilium development (based on CRISPR); Ciliopathies; Alstrom syndrome; Bardet-Biedl syndrome"	"Intraflagellar transport; Hedgehog 'off' state"	"7"	"0"	"211.7"	"114.0"	"239.0"	"203.8"	"228.8"	"208.9"	"253.5"	"219.6"	"330.0"	"464.2"	"850.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UHN6"	"Cell surface hyaluronidase OS=Homo sapiens OX=9606 GN=CEMIP2 PE=1 SV=1"	"1"	"1"	"1"	"1"	"1383"	"154.3"	"8.15"	""	"2.19"	""	"1"	"other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf10162, Pf15711"	"23670"	"ENSG00000135048"	"CEMIP2"	"A6H8W9; B2RTQ6; hsa:23670; Q5T838; Q5T839; Q5T840; Q5T841; Q8NBP6; Q9P2D5; Q9UHN6"	""	""	"0"	"0"	"6.6"	"5.8"	"5.6"	"9.0"	"12.0"	"7.3"	"6.3"	"14.6"	"27.3"	"74.3"	"78.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95777"	"U6 snRNA-associated Sm-like protein LSm8 OS=Homo sapiens OX=9606 GN=LSM8 PE=1 SV=3"	"7"	"1"	"2"	"1"	"96"	"10.4"	"4.48"	"256.01"	"2.19"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf01423"	"51691"	"ENSG00000128534"	"LSM8"	"hsa:51691; O95777"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"39.5"	"40.4"	"66.5"	"46.0"	"61.1"	"50.1"	"71.9"	"89.2"	"197.4"	"334.3"	"529.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96PY5"	"Formin-like protein 2 OS=Homo sapiens OX=9606 GN=FMNL2 PE=1 SV=3"	"1"	"1"	"2"	"1"	"1086"	"123.2"	"7.40"	"293.89"	"2.18"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"cytosol"	"cytoskeletal activity;other molecular function"	"Pf02181, Pf06367, Pf06371"	"114793"	"ENSG00000157827"	"FMNL2"	"B2RZH5; hsa:114793; Q14CC9; Q4ZG52; Q8N3E0; Q96PY5"	"Epithelial to mesenchymal transition in colorectal cancer"	"RHOC GTPase cycle; CDC42 GTPase cycle; RHO GTPases Activate Formins"	"4"	"0"	"13.0"	"7.0"	"15.3"	"12.9"	"17.8"	"13.8"	"20.3"	"16.9"	"18.4"	"36.1"	"44.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14832"	"Phytanoyl-CoA dioxygenase, peroxisomal OS=Homo sapiens OX=9606 GN=PHYH PE=1 SV=1"	"2"	"1"	"1"	"1"	"338"	"38.5"	"8.47"	""	"2.18"	""	"1"	"other metabolic processes"	"cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf05721"	"5264"	"ENSG00000107537"	"PHYH"	"A8MTS8; B1ALH5; hsa:5264; O14832"	""	"TYSND1 cleaves peroxisomal proteins; Alpha-oxidation of phytanate"	"3"	"0"	"129.4"	"106.9"	"131.6"	"120.8"	"138.1"	"130.3"	"138.8"	"164.3"	"298.0"	"568.5"	"814.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6UW63"	"Protein O-glucosyltransferase 2 OS=Homo sapiens OX=9606 GN=POGLUT2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"502"	"58.0"	"7.71"	"274.96"	"2.18"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00630, Pf05686"	"79070"	"ENSG00000134901"	"POGLUT2"	"hsa:79070; Q53HL3; Q6UW63; Q9BVD2"	""	""	"0"	"0"	"6.7"	"7.3"	"17.0"	"10.2"	"8.2"	"10.1"	"12.5"	"16.0"	"31.5"	"62.8"	"84.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H4X1"	"Regulator of cell cycle RGCC OS=Homo sapiens OX=9606 GN=RGCC PE=1 SV=1"	"8"	"1"	"2"	"1"	"137"	"14.6"	"4.75"	"267.66"	"2.18"	"1"	"1"	"cell cycle OR cell proliferation;stress response;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf15151"	"28984"	"ENSG00000102760"	"RGCC"	"hsa:28984; Q6NZ48; Q9H4X1; Q9UL69"	""	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"	"1"	"0"	"7.9"	"8.5"	"10.2"	"9.0"	"10.6"	"10.5"	"11.0"	"12.2"	"10.0"	"12.1"	"14.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BRJ6"	"Uncharacterized protein C7orf50 OS=Homo sapiens OX=9606 GN=C7orf50 PE=1 SV=1"	"7"	"1"	"2"	"1"	"194"	"22.1"	"9.64"	"313.50"	"2.18"	"1"	"1"	""	""	""	"Pf10180"	"84310"	"ENSG00000146540"	"C7orf50"	"hsa:84310; Q9BRJ6"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43818"	"U3 small nucleolar RNA-interacting protein 2 OS=Homo sapiens OX=9606 GN=RRP9 PE=1 SV=1"	"1"	"1"	"2"	"1"	"475"	"51.8"	"7.85"	"234.45"	"2.18"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00400"	"9136"	"ENSG00000114767"	"RRP9"	"B2R996; hsa:9136; O43818; Q8IZ30"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"68.3"	"60.9"	"55.6"	"56.1"	"72.5"	"59.8"	"73.9"	"94.5"	"115.0"	"203.6"	"275.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P79522"	"Proline-rich protein 3 OS=Homo sapiens OX=9606 GN=PRR3 PE=1 SV=2"	"3"	"1"	"2"	"1"	"188"	"20.6"	"9.83"	"250.54"	"2.18"	"1"	"1"	""	""	"other molecular function"	"Pf00642"	"80742"	"ENSG00000204576; ENSG00000206491; ENSG00000223766; ENSG00000223887; ENSG00000228186; ENSG00000229202; ENSG00000233564"	"PRR3"	"A1A4H4; hsa:80742; P79522; Q5RJB5; Q5STN6"	""	""	"0"	"0"	"256.8"	"198.2"	"249.0"	"242.5"	"243.1"	"203.5"	"269.4"	"326.9"	"380.1"	"474.8"	"636.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N7R7"	"Cyclin-Y-like protein 1 OS=Homo sapiens OX=9606 GN=CCNYL1 PE=1 SV=2"	"5"	"1"	"2"	"1"	"359"	"40.7"	"6.07"	"291.90"	"2.17"	"1"	"1"	"other biological processes"	"plasma membrane;other membranes"	"enzyme regulator activity;other molecular function"	"Pf00134"	"151195"	"ENSG00000163249"	"CCNYL1"	"hsa:151195; Q6NX60; Q8N7R7"	""	""	"0"	"0"	"6.9"	"5.2"	"8.0"	"9.0"	"9.4"	"7.7"	"10.9"	"14.8"	"21.6"	"43.9"	"47.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43396"	"Thioredoxin-like protein 1 OS=Homo sapiens OX=9606 GN=TXNL1 PE=1 SV=3"	"2"	"1"	"1"	"1"	"289"	"32.2"	"4.96"	""	"2.17"	""	"1"	""	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00085, Pf06201"	"9352"	"ENSG00000091164"	"TXNL1"	"hsa:9352; O43396"	""	"RND2 GTPase cycle; RHOV GTPase cycle; RHOU GTPase cycle; RND3 GTPase cycle; RND1 GTPase cycle; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle"	"7"	"0"	"55.1"	"43.2"	"68.9"	"56.9"	"69.0"	"56.7"	"76.6"	"103.4"	"147.8"	"246.7"	"379.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12979"	"Active breakpoint cluster region-related protein OS=Homo sapiens OX=9606 GN=ABR PE=1 SV=2"	"1"	"1"	"2"	"1"	"859"	"97.5"	"6.55"	"247.33"	"2.16"	"1"	"1"	"signal transduction;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity"	"Pf00168, Pf00169, Pf00620, Pf00621"	"29"	"ENSG00000159842; ENSG00000276016; ENSG00000278741"	"ABR"	"B3KW89; B7Z6H7; D3DTH3; D3DTH4; F5H3S2; F5H8B3; hsa:29; Q12979; Q13693; Q13694"	""	"RAC1 GTPase cycle; NRAGE signals death through JNK; G alpha (12/13) signalling events; RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOB GTPase cycle"	"9"	"0"	"102.0"	"72.3"	"106.7"	"92.9"	"103.1"	"111.4"	"128.1"	"153.6"	"335.8"	"567.3"	"665.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13613"	"Myotubularin-related protein 1 OS=Homo sapiens OX=9606 GN=MTMR1 PE=1 SV=4"	"1"	"1"	"2"	"1"	"665"	"74.6"	"7.14"	"241.12"	"2.16"	"1"	"1"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf02893, Pf06602"	"8776"	"ENSG00000063601"	"MTMR1"	"A0A024RC07; hsa:8776; Q13613; Q9UBX6; Q9UEM0; Q9UQD5"	""	"RHOF GTPase cycle; Synthesis of PIPs at the plasma membrane"	"2"	"0"	"62.1"	"57.6"	"63.4"	"53.0"	"56.9"	"59.8"	"123.7"	"252.3"	"359.0"	"316.2"	"286.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95707"	"Ribonuclease P protein subunit p29 OS=Homo sapiens OX=9606 GN=POP4 PE=1 SV=2"	"5"	"2"	"3"	"2"	"220"	"25.4"	"10.07"	"568.60"	"2.16"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01868"	"10775"	"ENSG00000105171"	"POP4"	"hsa:10775; O95707; Q5XKL7; Q6FHW9; Q9UQQ3"	""	"tRNA processing in the nucleus"	"1"	"0"	"61.7"	"70.3"	"56.2"	"64.7"	"64.1"	"71.1"	"88.9"	"99.1"	"113.8"	"200.5"	"275.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5T6C5"	"Ataxin-7-like protein 2 OS=Homo sapiens OX=9606 GN=ATXN7L2 PE=1 SV=1"	"1"	"1"	"1"	"1"	"722"	"77.1"	"9.23"	""	"2.16"	""	"1"	""	""	""	"Pf08313"	"127002"	"ENSG00000162650"	"ATXN7L2"	"hsa:127002; Q5T6C5"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UJW0"	"Dynactin subunit 4 OS=Homo sapiens OX=9606 GN=DCTN4 PE=1 SV=1"	"2"	"1"	"2"	"1"	"460"	"52.3"	"7.34"	"279.24"	"2.16"	"1"	"1"	""	"cytosol;cytoskeleton;nucleus;other cell component"	""	"Pf05502"	"51164"	"ENSG00000132912"	"DCTN4"	"B3KWW0; D3DQH0; E5RGT5; hsa:51164; Q8TAN8; Q9UJW0"	""	"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; MHC class II antigen presentation; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic"	"4"	"0"	"6.4"	"6.6"	"2.3"	"7.7"	"6.8"	"4.0"	"8.8"	"13.1"	"53.0"	"143.0"	"275.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BXI6"	"TBC1 domain family member 10A OS=Homo sapiens OX=9606 GN=TBC1D10A PE=1 SV=1"	"2"	"1"	"2"	"1"	"508"	"57.1"	"8.44"	"239.80"	"2.15"	"1"	"1"	"protein metabolism;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00566"	"83874"	"ENSG00000099992"	"TBC1D10A"	"B3KXT8; hsa:83874; O76053; Q20WK7; Q543A2; Q9BXI6"	"Deregulation of Rab and Rab effector genes in bladder cancer"	"TBC/RABGAPs"	"2"	"0"	"11.7"	"7.1"	"12.7"	"9.6"	"10.6"	"9.9"	"17.0"	"22.7"	"55.4"	"76.8"	"89.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96BN2"	"Transcriptional adapter 1 OS=Homo sapiens OX=9606 GN=TADA1 PE=1 SV=1"	"3"	"1"	"1"	"1"	"335"	"37.4"	"7.39"	""	"2.15"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf12767"	"117143"	"ENSG00000152382"	"TADA1"	"A8K4J9; hsa:117143; Q96BN2"	""	"HATs acetylate histones"	"1"	"0"	"4.3"	"9.5"	"6.2"	"6.8"	"7.9"	"5.2"	"6.9"	"11.7"	"31.4"	"72.5"	"100.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P032"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 OS=Homo sapiens OX=9606 GN=NDUFAF4 PE=1 SV=1"	"3"	"1"	"2"	"1"	"175"	"20.3"	"8.82"	"250.45"	"2.15"	"1"	"1"	"cell organization and biogenesis;stress response;other biological processes"	"other membranes;cytosol;mitochondrion"	"other molecular function"	"Pf06784"	"29078"	"ENSG00000123545"	"NDUFAF4"	"B2R4J5; hsa:29078; Q9P032"	""	"Complex I biogenesis"	"1"	"0"	"131.1"	"125.5"	"147.2"	"121.6"	"153.7"	"129.4"	"145.8"	"165.2"	"312.8"	"650.0"	"833.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q68D86"	"Coiled-coil domain-containing protein 102B OS=Homo sapiens OX=9606 GN=CCDC102B PE=1 SV=4"	"4"	"1"	"1"	"1"	"513"	"60.4"	"5.95"	""	"2.15"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis"	"cytoskeleton;other cell component"	"other molecular function"	""	"79839"	"ENSG00000150636"	"CCDC102B"	"A1A4H1; hsa:79839; Q68D86; Q7Z467; Q8NDK7; Q9H5C1"	""	""	"0"	"0"	"25.9"	"24.7"	"31.3"	"23.5"	"22.3"	"27.8"	"34.3"	"53.2"	"201.0"	"296.1"	"326.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13418"	"Integrin-linked protein kinase OS=Homo sapiens OX=9606 GN=ILK PE=1 SV=2"	"2"	"1"	"1"	"1"	"452"	"51.4"	"8.07"	""	"2.15"	""	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf07714, Pf12796"	"3611"	"ENSG00000166333"	"ILK"	"B7Z1I0; B7Z418; D3DQU0; hsa:3611; P57043; Q13418; Q68DZ3"	"Integrin-mediated cell adhesion; Primary focal segmental glomerulosclerosis (FSGS); Focal adhesion; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; PPAR signaling pathway; Eukaryotic transcription initiation; Endometrial cancer; Acute viral myocarditis; Genes controlling nephrogenesis; Development of ureteric collection system; 2q37 copy number variation syndrome"	"Localization of the PINCH-ILK-PARVIN complex to focal adhesions"	"13"	"0"	"43.5"	"42.9"	"53.6"	"48.0"	"55.7"	"52.6"	"57.9"	"91.4"	"257.0"	"370.9"	"396.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14181"	"DNA polymerase alpha subunit B OS=Homo sapiens OX=9606 GN=POLA2 PE=1 SV=2"	"2"	"1"	"1"	"1"	"598"	"65.9"	"5.24"	""	"2.15"	""	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;transport"	"cytosol;nucleus"	"nucleic acid binding activity"	"Pf04042, Pf08418"	"23649"	"ENSG00000014138"	"POLA2"	"B4DNB4; hsa:23649; Q14181; Q9BPV3"	"Pyrimidine metabolism; G1 to S cell cycle control; DNA replication"	"Activation of the pre-replicative complex; Defective pyroptosis; Inhibition of replication initiation of damaged DNA by RB1/E2F1; Polymerase switching on the C-strand of the telomere; Telomere C-strand synthesis initiation; DNA replication initiation; Polymerase switching; Removal of the Flap Intermediate"	"12"	"0"	"12.7"	"14.5"	"17.0"	"9.6"	"16.7"	"15.9"	"13.2"	"24.7"	"71.9"	"288.2"	"465.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IXK0"	"Polyhomeotic-like protein 2 OS=Homo sapiens OX=9606 GN=PHC2 PE=1 SV=1"	"1"	"1"	"2"	"1"	"858"	"90.7"	"8.69"	"306.99"	"2.15"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00536, Pf16616"	"1912"	"ENSG00000134686"	"PHC2"	"A1L4Q1; A8KA40; D3DPR2; hsa:1912; Q2TAL3; Q5T0C1; Q6NUJ6; Q6ZQR1; Q8IXK0; Q8N306; Q8TAG8; Q96BL4; Q9Y4Y7"	""	"SUMOylation of transcription cofactors; SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Oxidative Stress Induced Senescence; SUMOylation of DNA methylation proteins; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Regulation of PTEN gene transcription"	"8"	"0"	"199.9"	"187.5"	"185.3"	"164.2"	"196.3"	"197.5"	"225.0"	"230.5"	"303.7"	"499.2"	"569.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NE18"	"Putative methyltransferase NSUN7 OS=Homo sapiens OX=9606 GN=NSUN7 PE=2 SV=4"	"2"	"1"	"1"	"1"	"718"	"81.0"	"8.75"	""	"2.15"	""	"1"	"other metabolic processes"	""	"nucleic acid binding activity;other molecular function"	"Pf01189"	"79730"	"ENSG00000179299"	"NSUN7"	"C9JI19; hsa:79730; Q8N9K8; Q8NE18; Q9H815"	""	""	"0"	"0"	"89.1"	"37.5"	"165.0"	"122.6"	"123.9"	"138.3"	"126.5"	"108.5"	"213.9"	"243.0"	"344.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P00352"	"Retinal dehydrogenase 1 OS=Homo sapiens OX=9606 GN=ALDH1A1 PE=1 SV=2"	"5"	"1"	"1"	"1"	"501"	"54.8"	"6.73"	""	"2.14"	""	"1"	"other metabolic processes;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00171"	"216"	"ENSG00000165092"	"ALDH1A1"	"hsa:216; O00768; P00352; Q5SYR1"	"Folate-alcohol and cancer pathway hypotheses; Fatty acid omega-oxidation; Dopaminergic neurogenesis; Amino acid metabolism; Ethanol effects on histone modifications; Disorders of fructose metabolism; Vitamin A and carotenoid metabolism"	"RA biosynthesis pathway; Ethanol oxidation; Fructose catabolism"	"10"	"0"	"36.3"	"11.2"	"55.6"	"38.0"	"36.5"	"39.3"	"43.9"	"52.7"	"131.9"	"617.1"	"1632.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q3T906"	"N-acetylglucosamine-1-phosphotransferase subunits alpha/beta OS=Homo sapiens OX=9606 GN=GNPTAB PE=1 SV=1"	"1"	"1"	"1"	"1"	"1256"	"143.5"	"7.17"	""	"2.14"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport"	"other membranes;ER/Golgi;other cytoplasmic organelle"	"other molecular function"	"Pf00066, Pf06464, Pf11380, Pf17101, Pf17102, Pf17103, Pf18440"	"79158"	"ENSG00000111670"	"GNPTAB"	"A2RRQ9; hsa:79158; Q3T906; Q3ZQK2; Q6IPW5; Q86TQ2; Q96N13; Q9ULL2"	""	""	"0"	"0"	"88.3"	"59.2"	"98.1"	"99.6"	"93.6"	"105.9"	"130.6"	"216.0"	"1005.4"	"642.1"	"590.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16560"	"U11/U12 small nuclear ribonucleoprotein 35 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP35 PE=1 SV=1"	"6"	"1"	"1"	"1"	"246"	"29.4"	"9.86"	""	"2.14"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076"	"11066"	"ENSG00000184209"	"SNRNP35"	"A8K262; hsa:11066; Q16560; Q5XKN9"	""	"mRNA Splicing - Minor Pathway"	"1"	"0"	"115.6"	"32.3"	"157.5"	"134.1"	"142.2"	"116.7"	"121.6"	"94.2"	"143.9"	"222.2"	"470.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H0B6"	"Kinesin light chain 2 OS=Homo sapiens OX=9606 GN=KLC2 PE=1 SV=1"	"1"	"1"	"2"	"1"	"622"	"68.9"	"7.15"	"255.03"	"2.14"	"1"	"1"	"other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity"	"Pf13424"	"64837"	"ENSG00000174996"	"KLC2"	"A8MXL7; B2RDY4; hsa:64837; Q9H0B6; Q9H9C8; Q9HA20"	"Alzheimer's disease and miRNA effects; Alzheimer's disease"	"MHC class II antigen presentation; COPI-dependent Golgi-to-ER retrograde traffic; Kinesins; RHO GTPases activate KTN1"	"6"	"0"	"87.8"	"84.4"	"99.6"	"87.0"	"96.4"	"93.1"	"110.1"	"134.2"	"339.6"	"831.2"	"976.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9C0C9"	"(E3-independent) E2 ubiquitin-conjugating enzyme OS=Homo sapiens OX=9606 GN=UBE2O PE=1 SV=3"	"1"	"1"	"1"	"1"	"1292"	"141.2"	"5.12"	""	"2.14"	""	"1"	"protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00179"	"63893"	"ENSG00000175931"	"UBE2O"	"A6NDU5; hsa:63893; Q69YP4; Q6PIZ2; Q86UA4; Q8N425; Q8TBN1; Q9BSW1; Q9C0C9; Q9H6E6; Q9H7E4; Q9H9B2"	""	"Antigen processing: Ubiquitination & Proteasome degradation"	"1"	"0"	"57.3"	"61.6"	"71.1"	"63.0"	"59.1"	"61.0"	"77.9"	"96.5"	"140.6"	"286.3"	"396.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75431"	"Metaxin-2 OS=Homo sapiens OX=9606 GN=MTX2 PE=1 SV=1"	"4"	"1"	"2"	"1"	"263"	"29.7"	"6.29"	"238.61"	"2.14"	"1"	"1"	"cell organization and biogenesis;transport"	"other membranes;mitochondrion;nucleus;other cell component"	""	"Pf10568, Pf17171"	"10651"	"ENSG00000128654"	"MTX2"	"A8JZZ4; hsa:10651; O75431; Q53S50; Q53SQ2; Q5M7Z6; Q8IZ68"	""	"Mitochondrial protein import; Cristae formation"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P53803"	"DNA-directed RNA polymerases I, II, and III subunit RPABC4 OS=Homo sapiens OX=9606 GN=POLR2K PE=1 SV=1"	"12"	"1"	"2"	"1"	"58"	"7.0"	"9.06"	"242.89"	"2.13"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03604"	"5440"	"ENSG00000147669"	"POLR2K"	"hsa:5440; P53803; Q6IBD4"	"Pyrimidine metabolism; Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; Activation of anterior HOX genes in hindbrain development during early embryogenesis; mRNA Splicing - Major Pathway; Cytosolic sensors of pathogen-associated DNA ; Viral Messenger RNA Synthesis; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Estrogen-dependent gene expression; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; Transcriptional regulation by small RNAs; B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase III Transcription Termination; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Inhibition of DNA recombination at telomere"	"57"	"0"	"100.5"	"46.4"	"91.7"	"75.6"	"67.0"	"81.9"	"89.8"	"125.1"	"245.0"	"254.6"	"315.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q504Q3"	"PAN2-PAN3 deadenylation complex catalytic subunit PAN2 OS=Homo sapiens OX=9606 GN=PAN2 PE=1 SV=3"	"1"	"1"	"1"	"1"	"1202"	"135.3"	"5.99"	""	"2.13"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00929, Pf13423"	"9924"	"ENSG00000135473"	"PAN2"	"hsa:9924; O75189; Q504Q3; Q76E12; Q8IVE1"	"Ectoderm differentiation; Ectoderm differentiation"	"Deadenylation of mRNA"	"3"	"0"	"21.9"	"21.9"	"25.4"	"20.4"	"20.5"	"22.8"	"28.2"	"30.3"	"42.8"	"77.6"	"81.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A6H8Y1"	"Transcription factor TFIIIB component B'' homolog OS=Homo sapiens OX=9606 GN=BDP1 PE=1 SV=3"	"1"	"1"	"2"	"1"	"2624"	"293.7"	"5.11"	"256.89"	"2.13"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf15963"	"55814"	"ENSG00000145734; ENSG00000273873"	"BDP1"	"A6H8Y1; hsa:55814; Q68DS6; Q68DY5; Q6MZL9; Q6PIM7; Q86W98; Q96LR8; Q9C0H4; Q9H197; Q9H1A1; Q9HAW1; Q9HAW2; Q9HCY0; Q9ULH9"	""	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q02880"	"DNA topoisomerase 2-beta OS=Homo sapiens OX=9606 GN=TOP2B PE=1 SV=3"	"0"	"1"	"2"	"1"	"1626"	"183.2"	"8.00"	"266.51"	"2.12"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00204, Pf00521, Pf01751, Pf02518, Pf08070, Pf16898"	"7155"	"ENSG00000077097"	"TOP2B"	"hsa:7155; Q02880; Q13600; Q9UMG8; Q9UQP8"	""	"SUMOylation of DNA replication proteins"	"1"	"0"	"46.6"	"43.9"	"39.8"	"43.1"	"52.1"	"41.7"	"53.1"	"70.5"	"128.9"	"450.5"	"1249.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22670"	"MHC class II regulatory factor RFX1 OS=Homo sapiens OX=9606 GN=RFX1 PE=1 SV=2"	"1"	"1"	"1"	"1"	"979"	"104.7"	"6.29"	""	"2.12"	""	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02257, Pf04589"	"5989"	"ENSG00000132005; ENSG00000288283"	"RFX1"	"hsa:5989; P22670"	"Alstrom syndrome"	""	"1"	"0"	"17.6"	"18.0"	"22.1"	"20.6"	"25.5"	"23.8"	"21.9"	"32.9"	"64.9"	"141.7"	"213.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O96020"	"G1/S-specific cyclin-E2 OS=Homo sapiens OX=9606 GN=CCNE2 PE=1 SV=1"	"2"	"1"	"1"	"1"	"404"	"46.7"	"7.83"	""	"2.12"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00134, Pf02984"	"9134"	"ENSG00000175305"	"CCNE2"	"hsa:9134; O95439; O96020"	"miRNA regulation of DNA damage response; Cell cycle; Parkinson's disease pathway; Retinoblastoma gene in cancer; PI3K-Akt signaling pathway; Ultraconserved region 339 modulation of tumor suppressor microRNAs in cancer; G1 to S cell cycle control; Measles virus infection; Small cell lung cancer; DNA damage response"	"TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest; CDK-mediated phosphorylation and removal of Cdc6; SCF(Skp2)-mediated degradation of p27/p21; Association of TriC/CCT with target proteins during biosynthesis; Cyclin D associated events in G1; Defective binding of RB1 mutants to E2F1,(E2F2, E2F3); DNA Damage/Telomere Stress Induced Senescence; G0 and Early G1; Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes; p53-Dependent G1 DNA Damage Response"	"21"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P2X3"	"Protein IMPACT OS=Homo sapiens OX=9606 GN=IMPACT PE=1 SV=2"	"3"	"1"	"1"	"1"	"320"	"36.5"	"4.97"	""	"2.12"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"other cell component"	"cytoskeletal activity;translation activity;other molecular function"	"Pf01205, Pf05773"	"55364"	"ENSG00000154059"	"IMPACT"	"A8MXG0; hsa:55364; Q49AM0; Q9H2X4; Q9P2X3"	""	"Response of EIF2AK4 (GCN2) to amino acid deficiency"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y399"	"28S ribosomal protein S2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS2 PE=1 SV=1"	"3"	"1"	"2"	"1"	"296"	"33.2"	"9.26"	"268.11"	"2.12"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00318"	"51116"	"ENSG00000122140"	"MRPS2"	"hsa:51116; Q5T899; Q9BSQ4; Q9Y399"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"58.6"	"54.2"	"75.2"	"56.5"	"73.2"	"63.3"	"80.6"	"114.0"	"187.1"	"297.5"	"405.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P2P2"	"Protein arginine N-methyltransferase 9 OS=Homo sapiens OX=9606 GN=PRMT9 PE=1 SV=1"	"2"	"1"	"1"	"1"	"845"	"94.4"	"5.25"	""	"2.12"	""	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"other cell component"	"other molecular function"	"Pf06325"	"90826"	"ENSG00000164169"	"PRMT9"	"A8KA39; B3KU92; hsa:90826; Q6P2P2; Q6ZR58; Q8N383; Q9BT55; Q9NT98"	""	""	"0"	"0"	"45.1"	"48.9"	"58.1"	"38.8"	"61.7"	"64.5"	"77.9"	"81.9"	"204.3"	"466.1"	"726.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94854"	"Uncharacterized protein KIAA0754 OS=Homo sapiens OX=9606 GN=KIAA0754 PE=2 SV=4"	"1"	"1"	"2"	"1"	"1291"	"135.1"	"4.21"	"309.57"	"2.11"	"1"	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"29.9"	"21.3"	"33.7"	"25.2"	"26.1"	"25.6"	"33.2"	"39.9"	"45.3"	"82.0"	"134.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"G2XKQ0"	"Small ubiquitin-related modifier 5 OS=Homo sapiens OX=9606 GN=SUMO1P1 PE=1 SV=2"	"7"	"1"	"1"	"1"	"101"	"11.5"	"5.52"	""	"2.11"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"nucleus"	"other molecular function"	"Pf11976"	""	""	"SUMO1P1"	"G2XKQ0"	""	""	"0"	"0"	"189.1"	"192.3"	"243.7"	"157.9"	"194.6"	"203.1"	"246.6"	"265.1"	"315.4"	"433.2"	"622.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UPU5"	"Ubiquitin carboxyl-terminal hydrolase 24 OS=Homo sapiens OX=9606 GN=USP24 PE=1 SV=3"	"0"	"1"	"2"	"1"	"2620"	"294.2"	"6.14"	"252.60"	"2.10"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf00443, Pf12030"	"23358"	"ENSG00000162402"	"USP24"	"hsa:23358; Q6ZSY2; Q8N2Y4; Q9NXD1; Q9UPU5"	""	"Ub-specific processing proteases"	"1"	"0"	"18.0"	"22.3"	"21.1"	"20.7"	"27.3"	"24.8"	"24.6"	"30.3"	"51.9"	"162.5"	"398.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2R4"	"Probable ATP-dependent RNA helicase DDX52 OS=Homo sapiens OX=9606 GN=DDX52 PE=1 SV=3"	"3"	"2"	"2"	"1"	"599"	"67.5"	"9.67"	"399.46"	"2.09"	"1"	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"9.4"	"6.1"	"9.8"	"7.1"	"10.3"	"10.4"	"8.8"	"21.8"	"40.0"	"64.3"	"93.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99627"	"COP9 signalosome complex subunit 8 OS=Homo sapiens OX=9606 GN=COPS8 PE=1 SV=1"	"5"	"1"	"1"	"1"	"209"	"23.2"	"5.38"	""	"2.09"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf10075"	"10920"	"ENSG00000198612"	"COPS8"	"A8K1H6; hsa:10920; Q53QS9; Q99627"	"Ciliary landscape; 2q37 copy number variation syndrome"	"Neddylation; DNA Damage Recognition in GG-NER; Cargo recognition for clathrin-mediated endocytosis; Formation of TC-NER Pre-Incision Complex"	"6"	"0"	"8.7"	"12.3"	"16.8"	"10.5"	"19.8"	"20.0"	"16.8"	"26.7"	"54.0"	"114.9"	"197.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3D9"	"28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2"	"5"	"1"	"2"	"1"	"190"	"21.8"	"8.90"	"295.78"	"2.08"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf10484"	"51649"	"ENSG00000181610"	"MRPS23"	"B2R6V3; hsa:51649; Q96Q24; Q9BWH8; Q9P053; Q9Y3D9"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"37.7"	"31.1"	"40.3"	"40.1"	"35.6"	"43.5"	"29.2"	"42.2"	"113.5"	"190.7"	"260.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14517"	"Protocadherin Fat 1 OS=Homo sapiens OX=9606 GN=FAT1 PE=1 SV=2"	"0"	"1"	"1"	"1"	"4588"	"506.0"	"5.00"	""	"2.08"	""	"1"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00008, Pf00028, Pf02210"	"2195"	"ENSG00000083857"	"FAT1"	"hsa:2195; Q14517"	"Primary focal segmental glomerulosclerosis (FSGS); Head and neck squamous cell carcinoma"	""	"2"	"0"	"50.8"	"52.0"	"58.3"	"58.2"	"72.9"	"60.6"	"71.9"	"77.9"	"163.0"	"314.9"	"345.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P00338"	"L-lactate dehydrogenase A chain OS=Homo sapiens OX=9606 GN=LDHA PE=1 SV=2"	"5"	"2"	"3"	"2"	"332"	"36.7"	"8.27"	"557.88"	"2.08"	"2"	"1"	"other metabolic processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00056, Pf02866"	"3939"	"ENSG00000134333; ENSG00000288299"	"LDHA"	"B4DKQ2; B7Z5E3; D3DQY3; F8W819; hsa:3939; P00338; Q53G53; Q6IBM7; Q6ZNV1; Q9UDE8; Q9UDE9"	"Cori cycle; HIF1A and PPARG regulation of glycolysis; Photodynamic therapy-induced HIF-1 survival signaling; VEGFA-VEGFR2 signaling; Amino acid metabolism; Clear cell renal cell carcinoma pathways; PI3K/AKT/mTOR - vitamin D3 signaling; Metabolic reprogramming in colon cancer; Aerobic glycolysis; Glycolysis in senescence; Orexin receptor pathway; CCL18 signaling pathway; Glucose metabolism in triple-negative breast cancer cells; Warburg effect modulated by deubiquitinating enzymes and their substrates; Lactate shuttle in glial cells; Glycolysis and gluconeogenesis; A network map of Macrophage-stimulating protein (MSP) signaling; Metabolic Epileptic Disorders"	"Pyruvate metabolism"	"19"	"0"	"13.6"	"21.5"	"17.4"	"12.2"	"15.8"	"9.8"	"15.7"	"28.4"	"41.2"	"60.1"	"79.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P1L8"	"39S ribosomal protein L14, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL14 PE=1 SV=1"	"6"	"1"	"1"	"1"	"145"	"15.9"	"10.24"	""	"2.08"	""	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00238"	"64928"	"ENSG00000180992"	"MRPL14"	"B2R575; hsa:64928; Q6P1L8; Q96Q72"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"21.8"	"25.9"	"30.9"	"24.3"	"27.8"	"28.4"	"36.4"	"42.1"	"69.5"	"134.5"	"175.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00165"	"HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2"	"5"	"2"	"3"	"2"	"279"	"31.6"	"4.92"	"494.09"	"2.07"	"2"	"1"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"other molecular function"	""	"10456"	"ENSG00000143575"	"HAX1"	"A8W4W9; A8W4X0; B4DUJ7; hsa:10456; O00165; Q5VYD5; Q5VYD7; Q96AU4; Q9BS80"	"Primary ovarian insufficiency"	""	"1"	"0"	"171.7"	"164.8"	"181.9"	"172.3"	"174.9"	"190.7"	"227.5"	"258.7"	"463.4"	"997.4"	"1573.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6UXN9"	"WD repeat-containing protein 82 OS=Homo sapiens OX=9606 GN=WDR82 PE=1 SV=1"	"5"	"2"	"2"	"2"	"313"	"35.1"	"7.69"	"295.76"	"2.06"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00400"	"80335"	"ENSG00000164091"	"WDR82"	"A8K5R5; hsa:80335; Q6UXN9; Q8TEB2"	""	"Formation of WDR5-containing histone-modifying complexes"	"1"	"0"	"180.8"	"186.2"	"151.9"	"149.0"	"178.9"	"167.4"	"208.0"	"293.6"	"549.8"	"987.5"	"1469.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62072"	"Mitochondrial import inner membrane translocase subunit Tim10 OS=Homo sapiens OX=9606 GN=TIMM10 PE=1 SV=1"	"16"	"1"	"1"	"1"	"90"	"10.3"	"6.29"	"762.12"	""	"1"	""	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf02953"	"26519"	"ENSG00000134809"	"TIMM10"	"A8K136; hsa:26519; P62072; Q9WV99; Q9WVA0; Q9Y5J8"	""	"Mitochondrial protein import"	"1"	"0"	"123.4"	"112.5"	"140.8"	"130.5"	"124.6"	"126.1"	"148.3"	"149.1"	"170.2"	"349.2"	"1374.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13617"	"Cullin-2 OS=Homo sapiens OX=9606 GN=CUL2 PE=1 SV=2"	"2"	"2"	"2"	"2"	"745"	"86.9"	"6.92"	"728.94"	""	"2"	""	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;signal transduction"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00888, Pf10557"	"8453"	"ENSG00000108094"	"CUL2"	"B3KT95; B7Z6K8; D3DRY6; G3V1S2; hsa:8453; O00200; Q13617; Q5T2B6; Q9UNF9"	"Type 2 papillary renal cell carcinoma; Hijack of ubiquitination by SARS-CoV-2"	"Neddylation; Regulation of expression of SLITs and ROBOs; Antigen processing: Ubiquitination & Proteasome degradation; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"	"6"	"0"	"26.3"	"17.5"	"16.0"	"23.2"	"25.0"	"22.4"	"28.9"	"36.1"	"143.8"	"529.6"	"979.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TEW8"	"Partitioning defective 3 homolog B OS=Homo sapiens OX=9606 GN=PARD3B PE=1 SV=2"	"2"	"2"	"2"	"2"	"1205"	"132.4"	"8.37"	"696.05"	""	"2"	""	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00595, Pf12053"	"117583"	"ENSG00000116117"	"PARD3B"	"E9PE87; hsa:117583; Q8IUC7; Q8IUC9; Q8TEW8; Q96DK9; Q96N09; Q96NX6; Q96NX7; Q96Q29"	""	""	"0"	"0"	"35.5"	"33.4"	"33.0"	"34.1"	"35.9"	"33.7"	"55.5"	"63.9"	"143.4"	"294.8"	"365.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q969F1"	"General transcription factor 3C polypeptide 6 OS=Homo sapiens OX=9606 GN=GTF3C6 PE=1 SV=1"	"8"	"1"	"1"	"1"	"213"	"24.0"	"4.21"	"683.90"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf10419"	"112495"	"ENSG00000155115"	"GTF3C6"	"hsa:112495; Q5VXN2; Q969F1"	""	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter"	"3"	"0"	"45.4"	"42.8"	"55.1"	"42.7"	"53.1"	"48.2"	"72.2"	"85.6"	"135.2"	"316.1"	"550.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IZL8"	"Proline-, glutamic acid- and leucine-rich protein 1 OS=Homo sapiens OX=9606 GN=PELP1 PE=1 SV=2"	"1"	"1"	"1"	"1"	"1130"	"119.6"	"4.34"	"672.61"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf08166, Pf08167"	"27043"	"ENSG00000141456"	"PELP1"	"hsa:27043; O15450; Q5EGN3; Q6NTE6; Q8IZL8; Q96FT1; Q9BU60"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; PTK6 Expression"	"2"	"0"	"49.3"	"44.4"	"58.9"	"50.7"	"48.1"	"26.6"	"70.4"	"102.1"	"133.4"	"292.4"	"440.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UN37"	"Vacuolar protein sorting-associated protein 4A OS=Homo sapiens OX=9606 GN=VPS4A PE=1 SV=1"	"3"	"1"	"1"	"1"	"437"	"48.9"	"7.80"	"667.59"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00004, Pf04212, Pf09336, Pf17862"	"27183"	"ENSG00000132612"	"VPS4A"	"B2RCB7; hsa:27183; Q8TF07; Q9UI03; Q9UN37; Q9Y582"	"Ebola virus infection in host; Ciliary landscape"	"Budding and maturation of HIV virion; Endosomal Sorting Complex Required For Transport (ESCRT); HCMV Late Events; Sealing of the nuclear envelope (NE) by ESCRT-III"	"6"	"0"	"14.2"	"15.1"	"12.8"	"15.8"	"11.9"	"11.9"	"14.3"	"24.1"	"41.0"	"90.7"	"110.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15392"	"Baculoviral IAP repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=BIRC5 PE=1 SV=3"	"9"	"1"	"1"	"1"	"142"	"16.4"	"5.90"	"665.21"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00653"	"332"	"ENSG00000089685"	"BIRC5"	"A2SUH6; B2R4R1; hsa:332; O15392; Q2I3N8; Q4VGX0; Q53F61; Q5MGC6; Q6FHL2; Q75SP2; Q9P2W8"	"Apoptosis modulation and signaling; Interleukin-11 signaling pathway; Apoptosis; Apoptosis-related network due to altered Notch3 in ovarian cancer; RAC1/PAK1/p38/MMP2 pathway; Photodynamic therapy-induced HIF-1 survival signaling; Photodynamic therapy-induced NF-kB survival signaling; Hepatitis C and hepatocellular carcinoma; VEGFA-VEGFR2 signaling; IL-4 signaling pathway; Chromosomal and microsatellite instability in colorectal cancer ; Extracellular vesicles in the crosstalk of cardiac cells; Gastrin signaling pathway; Hepatitis B infection"	"Separation of Sister Chromatids; Neddylation; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; SUMOylation of DNA replication proteins; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Interleukin-4 and Interleukin-13 signaling; TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"	"24"	"0"	"82.9"	"91.6"	"95.2"	"83.3"	"95.7"	"77.4"	"101.8"	"181.6"	"230.2"	"267.3"	"398.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"B7ZAP0"	"Rab GTPase-activating protein 1-like, isoform 10 OS=Homo sapiens OX=9606 GN=RABGAP1L PE=1 SV=1"	"4"	"1"	"2"	"1"	"253"	"29.0"	"5.33"	"651.11"	""	"1"	""	""	""	""	""	"9910"	"ENSG00000152061"	"RABGAP1L"	"B7ZAA4; B7ZAP0; hsa:9910"	""	""	"0"	"0"	"662.0"	"635.5"	"773.1"	"618.4"	"711.3"	"693.4"	"838.7"	"991.6"	"1436.2"	"2474.9"	"3231.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H6R0"	"ATP-dependent RNA helicase DHX33 OS=Homo sapiens OX=9606 GN=DHX33 PE=1 SV=2"	"2"	"1"	"1"	"1"	"707"	"78.8"	"8.91"	"648.94"	""	"1"	""	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"56919"	"ENSG00000005100"	"DHX33"	"B4DHF9; hsa:56919; Q4G149; Q5CZ73; Q9H5M9; Q9H6R0"	""	""	"0"	"0"	"30.7"	"38.5"	"26.7"	"23.4"	"24.8"	"27.5"	"27.8"	"33.7"	"46.6"	"73.7"	"114.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NB46"	"Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C OS=Homo sapiens OX=9606 GN=ANKRD52 PE=1 SV=3"	"3"	"2"	"2"	"2"	"1076"	"115.0"	"6.48"	"645.10"	""	"2"	""	""	""	""	"Pf00023, Pf12796"	"283373"	"ENSG00000139645"	"ANKRD52"	"A6NE79; B1Q2K2; hsa:283373; Q8NB46"	""	""	"0"	"0"	"11.2"	"10.4"	"15.3"	"17.5"	"15.0"	"15.1"	"14.1"	"24.2"	"49.3"	"91.6"	"113.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NYJ1"	"Cytochrome c oxidase assembly factor 4 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=COA4 PE=1 SV=2"	"17"	"1"	"1"	"1"	"87"	"10.1"	"6.04"	"636.27"	""	"1"	""	"cell organization and biogenesis"	"mitochondrion"	""	""	"51287"	"ENSG00000181924"	"COA4"	"B2RAA0; hsa:51287; Q69YU4; Q9NYJ1"	""	"Mitochondrial protein import"	"1"	"0"	"72.2"	"52.2"	"89.9"	"88.8"	"90.1"	"83.9"	"86.5"	"95.9"	"111.9"	"148.9"	"170.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82912"	"28S ribosomal protein S11, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS11 PE=1 SV=2"	"9"	"1"	"1"	"1"	"194"	"20.6"	"10.81"	"620.08"	""	"1"	""	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00411"	"64963"	"ENSG00000181991"	"MRPS11"	"B2RD52; hsa:64963; P82912; Q969D7; Q96GI3; Q9BYC3"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"6.0"	"6.2"	"9.4"	"8.2"	"7.6"	"6.8"	"7.4"	"11.7"	"17.5"	"30.7"	"47.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P02768"	"Serum albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2"	"2"	"1"	"1"	"1"	"609"	"69.3"	"6.28"	"618.94"	""	"1"	""	"stress response;other biological processes"	"non-structural extracellular;ER/Golgi;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00273"	"213"	"ENSG00000163631"	"ALB"	"E7ESS9; hsa:213; O95574; P02768; P04277; Q13140; Q645G4; Q68DN5; Q6UXK4; Q86YG0; Q8IUK7; Q9P157; Q9P1I7; Q9UHS3; Q9UJZ0"	"Selenium micronutrient network; Vitamin B12 metabolism; Folate metabolism; Complement system; VEGFA-VEGFR2 signaling"	"Scavenging of heme from plasma; Platelet degranulation ; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Cytoprotection by HMOX1; Aspirin ADME; Ciprofloxacin ADME; Recycling of bile acids and salts; Prednisone ADME; Heme degradation; HDL remodeling; Heme biosynthesis"	"17"	"0"	"16.4"	"27.3"	"21.7"	"13.2"	"19.2"	"15.0"	"25.3"	"43.6"	"89.0"	"114.5"	"119.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N1I0"	"Dedicator of cytokinesis protein 4 OS=Homo sapiens OX=9606 GN=DOCK4 PE=1 SV=3"	"1"	"1"	"1"	"1"	"1966"	"225.1"	"7.65"	"618.08"	""	"1"	""	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf06920, Pf07653, Pf14429, Pf16172, Pf20421, Pf20422"	"9732"	"ENSG00000128512"	"DOCK4"	"hsa:9732; O14584; O94824; Q8N1I0; Q8NB45"	""	"RAC1 GTPase cycle; Factors involved in megakaryocyte development and platelet production; RHOG GTPase cycle; RAC2 GTPase cycle"	"4"	"0"	"6.4"	"7.7"	"8.1"	"10.3"	"19.9"	"39.3"	"57.0"	"78.5"	"33.4"	"45.8"	"43.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13547"	"Histone deacetylase 1 OS=Homo sapiens OX=9606 GN=HDAC1 PE=1 SV=1"	"4"	"2"	"2"	"1"	"482"	"55.1"	"5.48"	"600.93"	""	"2"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00850"	"3065"	"ENSG00000116478"	"HDAC1"	"hsa:3065; Q13547; Q92534"	"Androgen receptor signaling pathway; Energy metabolism; Cell cycle; TNF-related weak inducer of apoptosis (TWEAK) signaling pathway; Neural crest differentiation; Retinoblastoma gene in cancer; Notch signaling; Apoptosis-related network due to altered Notch3 in ovarian cancer; Initiation of transcription and translation elongation at the HIV-1 LTR; MECP2 and associated Rett syndrome; IL6 signaling pathway; Valproic acid pathway; VEGFA-VEGFR2 signaling; Ethanol effects on histone modifications; Rett syndrome causing genes; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; Ciliary landscape; Transcription co-factors SKI and SKIL protein partners; Overlap between signal transduction pathways contributing to LMNA laminopathies; Opioid receptor pathways; 15q11q13 copy number variation; Notch signaling pathway; Sudden infant death syndrome (SIDS) susceptibility pathways"	"NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; Potential therapeutics for SARS; SUMOylation of chromatin organization proteins; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes; Formation of the beta-catenin:TCF transactivating complex; SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Deactivation of the beta-catenin transactivating complex; Regulation of PTEN gene transcription; HDACs deacetylate histones; Estrogen-dependent gene expression; MECP2 regulates transcription of neuronal ligands; Factors involved in megakaryocyte development and platelet production; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Downregulation of SMAD2/3:SMAD4 transcriptional activity; p75NTR negatively regulates cell cycle via SC1; NOTCH1 Intracellular Domain Regulates Transcription; Notch-HLH transcription pathway; Regulation of MECP2 expression and activity; STAT3 nuclear events downstream of ALK signaling; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; G1/S-Specific Transcription; Regulation of TP53 Activity through Acetylation; Transcription of E2F targets under negative control by DREAM complex; Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1; MECP2 regulates neuronal receptors and channels; Repression of WNT target genes; Loss of MECP2 binding ability to 5mC-DNA"	"54"	"0"	"38.1"	"28.2"	"37.6"	"47.2"	"46.8"	"43.3"	"43.5"	"54.2"	"83.2"	"169.5"	"287.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96BX8"	"MOB kinase activator 3A OS=Homo sapiens OX=9606 GN=MOB3A PE=1 SV=1"	"6"	"1"	"1"	"1"	"217"	"25.4"	"8.63"	"593.07"	""	"1"	""	"signal transduction;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf03637"	"126308"	"ENSG00000172081"	"MOB3A"	"B3KTF1; hsa:126308; O75249; Q8TF69; Q96BX8"	""	""	"0"	"0"	"0.0"	"0.0"	"0.0"	"2.5"	"3.9"	"0.0"	"4.9"	"14.9"	"64.8"	"62.5"	"123.2"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2X9"	"Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1"	"2"	"1"	"1"	"1"	"895"	"96.9"	"8.48"	"589.32"	""	"1"	""	"developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00096"	"23528"	"ENSG00000162702"	"ZNF281"	"A6NF48; B3KMX2; hsa:23528; Q5RKW5; Q9NY92; Q9Y2X9"	"Mesodermal commitment pathway"	""	"1"	"0"	"16.8"	"18.5"	"18.4"	"15.5"	"19.7"	"15.6"	"25.3"	"25.0"	"33.6"	"47.7"	"65.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y6I4"	"Ubiquitin carboxyl-terminal hydrolase 3 OS=Homo sapiens OX=9606 GN=USP3 PE=1 SV=2"	"3"	"1"	"1"	"1"	"520"	"58.9"	"8.18"	"579.16"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf00443, Pf02148"	"9960"	"ENSG00000140455"	"USP3"	"B4DVU5; F5H1A6; hsa:9960; Q8WVD0; Q9Y6I4"	""	"Ub-specific processing proteases"	"1"	"0"	"54.9"	"50.5"	"52.9"	"45.3"	"48.9"	"46.0"	"58.9"	"75.9"	"103.9"	"93.9"	"97.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TBZ6"	"tRNA methyltransferase 10 homolog A OS=Homo sapiens OX=9606 GN=TRMT10A PE=1 SV=1"	"5"	"1"	"1"	"1"	"339"	"39.7"	"7.65"	"569.48"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;cytoskeleton;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01746"	"93587"	"ENSG00000145331"	"TRMT10A"	"B2R8X7; hsa:93587; Q8TBZ6; Q9Y2T9"	""	"tRNA modification in the nucleus and cytosol"	"1"	"0"	"9.5"	"15.7"	"16.9"	"11.1"	"16.7"	"13.6"	"17.6"	"24.9"	"30.4"	"45.2"	"45.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IVW6"	"AT-rich interactive domain-containing protein 3B OS=Homo sapiens OX=9606 GN=ARID3B PE=1 SV=2"	"3"	"1"	"1"	"1"	"561"	"60.6"	"7.52"	"562.93"	""	"1"	""	"other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf01388"	"10620"	"ENSG00000179361"	"ARID3B"	"hsa:10620; O95443; Q59HC9; Q6P9C9; Q8IVW6"	""	""	"0"	"0"	"31.6"	"23.8"	"37.6"	"30.5"	"26.0"	"34.5"	"40.5"	"42.1"	"52.1"	"58.8"	"77.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TDX7"	"Serine/threonine-protein kinase Nek7 OS=Homo sapiens OX=9606 GN=NEK7 PE=1 SV=1"	"4"	"1"	"1"	"1"	"302"	"34.5"	"8.25"	"561.07"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"140609"	"ENSG00000151414"	"NEK7"	"A6NGT8; hsa:140609; Q8TDX7"	"Ciliary landscape"	"EML4 and NUDC in mitotic spindle formation; Nuclear Pore Complex (NPC) Disassembly; Activation of NIMA Kinases NEK9, NEK6, NEK7"	"4"	"0"	"19.0"	"21.6"	"32.8"	"23.4"	"28.2"	"23.8"	"37.1"	"47.0"	"173.5"	"330.8"	"373.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P15336"	"Cyclic AMP-dependent transcription factor ATF-2 OS=Homo sapiens OX=9606 GN=ATF2 PE=1 SV=4"	"3"	"1"	"1"	"1"	"505"	"54.5"	"7.88"	"559.95"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00170"	"1386"	"ENSG00000115966"	"ATF2"	"A1L3Z2; A4D7U4; A4D7U5; A4D7V1; D3DPE9; G8JLM5; hsa:1386; P15336; Q13000; Q3B7B7; Q4ZFU9; Q53RY2; Q8TAR1; Q96JT8"	"Energy metabolism; IL-1 signaling pathway; B cell receptor signaling pathway; AGE/RAGE pathway; ATM signaling pathway; Interleukin-1 (IL-1) structural pathway; Myometrial relaxation and contraction pathways; MAPK signaling pathway; ATM signaling in development and disease ; VEGFA-VEGFR2 signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; IL-4 signaling pathway; DNA IR-double strand breaks and cellular response via ATM; Ethanol effects on histone modifications; p38 MAPK signaling pathway; PI3K-Akt signaling pathway; Thermogenesis; Gastrin signaling pathway; Hepatitis B infection; Thyroid hormones production and peripheral downstream signaling effects; Host-pathogen interaction of human coronaviruses - MAPK signaling; Pleural mesothelioma; 10q11.21q11.23 copy number variation syndrome; T-cell receptor signaling pathway"	"Heme signaling; Estrogen-dependent gene expression; HATs acetylate histones; NGF-stimulated transcription; Regulation of PTEN gene transcription; TP53 Regulates Transcription of DNA Repair Genes; Circadian Clock; Transcriptional activation of mitochondrial biogenesis; Activation of the AP-1 family of transcription factors; Response of EIF2AK4 (GCN2) to amino acid deficiency"	"34"	"0"	"18.7"	"28.0"	"26.9"	"17.9"	"25.2"	"22.8"	"28.4"	"28.2"	"47.1"	"75.7"	"109.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P021"	"Cysteine-rich PDZ-binding protein OS=Homo sapiens OX=9606 GN=CRIPT PE=1 SV=1"	"12"	"1"	"1"	"1"	"101"	"11.2"	"9.47"	"557.75"	""	"1"	""	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf10235"	"9419"	"ENSG00000119878"	"CRIPT"	"hsa:9419; Q9P021"	""	""	"0"	"0"	"31.4"	"20.5"	"34.5"	"34.5"	"36.0"	"35.9"	"41.3"	"41.9"	"57.8"	"72.5"	"90.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IY81"	"pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 OS=Homo sapiens OX=9606 GN=FTSJ3 PE=1 SV=2"	"2"	"1"	"1"	"1"	"847"	"96.5"	"8.40"	"539.42"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf01728, Pf07780, Pf11861"	"117246"	"ENSG00000108592"	"FTSJ3"	"B2RCA5; D3DU22; hsa:117246; Q8IY81; Q8N3A3; Q8WXX1; Q9BWM4; Q9NXT6"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"14.3"	"15.9"	"16.1"	"8.3"	"17.1"	"17.8"	"20.9"	"33.6"	"53.1"	"94.4"	"134.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P26583"	"High mobility group protein B2 OS=Homo sapiens OX=9606 GN=HMGB2 PE=1 SV=2"	"6"	"1"	"1"	"1"	"209"	"24.0"	"7.81"	"539.06"	""	"1"	""	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00505, Pf09011"	"3148"	"ENSG00000164104"	"HMGB2"	"B2R4K8; D3DP37; hsa:3148; P26583; Q5U072"	"Retinoblastoma gene in cancer; Ectoderm differentiation; Ectoderm differentiation"	"Apoptosis induced DNA fragmentation"	"4"	"0"	"73.3"	"66.1"	"83.8"	"81.7"	"75.6"	"82.6"	"110.9"	"125.8"	"234.3"	"440.0"	"558.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y365"	"START domain-containing protein 10 OS=Homo sapiens OX=9606 GN=STARD10 PE=1 SV=2"	"5"	"1"	"1"	"1"	"291"	"33.0"	"7.12"	"536.10"	""	"1"	""	"transport"	"other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf01852"	"10809"	"ENSG00000214530"	"STARD10"	"hsa:10809; O60532; Q9Y365"	""	"Synthesis of PC"	"1"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"1.9"	"0.3"	"27.6"	"190.3"	"221.3"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15631"	"Translin OS=Homo sapiens OX=9606 GN=TSN PE=1 SV=1"	"5"	"1"	"1"	"1"	"228"	"26.2"	"6.44"	"535.18"	""	"1"	""	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01997"	"7247"	"ENSG00000211460"	"TSN"	"B7Z3X8; hsa:7247; Q15631; Q5U0K7"	""	"Small interfering RNA (siRNA) biogenesis"	"1"	"0"	"23.1"	"32.8"	"27.1"	"20.8"	"22.2"	"22.7"	"32.6"	"53.5"	"80.6"	"126.7"	"213.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96RL1"	"BRCA1-A complex subunit RAP80 OS=Homo sapiens OX=9606 GN=UIMC1 PE=1 SV=2"	"2"	"1"	"1"	"1"	"719"	"79.7"	"5.45"	"535.17"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf18282"	"51720"	"ENSG00000087206"	"UIMC1"	"A8MSA1; B3KMZ1; B4E3N2; hsa:51720; Q5XKQ1; Q7Z3W7; Q8N5B9; Q96RL1; Q9BZR1; Q9BZR5; Q9UHX7"	"5q35 copy number variation"	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; Nonhomologous End-Joining (NHEJ); Metalloprotease DUBs"	"6"	"0"	"109.1"	"98.7"	"125.1"	"128.0"	"127.0"	"139.3"	"139.5"	"166.6"	"263.7"	"332.8"	"335.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P27824"	"Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2"	"3"	"1"	"1"	"1"	"592"	"67.5"	"4.60"	"528.01"	""	"1"	""	"protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;translational apparatus;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00262"	"821"	"ENSG00000127022; ENSG00000283777"	"CANX"	"B2R5V8; B4DGP8; B4E2T8; D3DWQ3; D6R9K3; hsa:821; P27824"	"15q11q13 copy number variation"	"Maturation of spike protein; MHC class II antigen presentation; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Interleukin-35 Signalling; Interleukin-27 signaling; Assembly of Viral Components at the Budding Site; Calnexin/calreticulin cycle; Maturation of spike protein"	"9"	"0"	"34.0"	"45.5"	"45.5"	"32.8"	"30.0"	"28.4"	"42.2"	"64.1"	"140.5"	"251.9"	"314.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P18615"	"Negative elongation factor E OS=Homo sapiens OX=9606 GN=NELFE PE=1 SV=3"	"5"	"1"	"1"	"1"	"380"	"43.2"	"9.33"	"526.18"	""	"1"	""	"other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"7936"	"ENSG00000204356; ENSG00000206268; ENSG00000206357; ENSG00000229363; ENSG00000231044; ENSG00000233801"	"NELFE"	"A2BE08; B4DUN1; B4DYX9; hsa:7936; P18615; Q5JP74; Q5JP75; Q96F56; Q9NPK2"	"Initiation of transcription and translation elongation at the HIV-1 LTR; 4p16.3 copy number variation"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes"	"16"	"0"	"13.6"	"16.7"	"10.4"	"10.3"	"8.7"	"6.3"	"15.4"	"24.8"	"50.6"	"106.3"	"129.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25490"	"Transcriptional repressor protein YY1 OS=Homo sapiens OX=9606 GN=YY1 PE=1 SV=2"	"4"	"1"	"1"	"1"	"414"	"44.7"	"6.25"	"516.20"	""	"1"	""	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00096"	"7528"	"ENSG00000100811"	"YY1"	"hsa:7528; P25490; Q14935"	"Sterol regulatory element-binding proteins (SREBP) signaling; Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4); Pleural mesothelioma"	"Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; UCH proteinases; DNA Damage Recognition in GG-NER; TFAP2 (AP-2) family regulates transcription of growth factors and their receptors"	"8"	"0"	"36.3"	"54.7"	"52.0"	"40.5"	"48.2"	"45.0"	"52.4"	"53.6"	"86.4"	"124.6"	"200.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P56181"	"NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV3 PE=1 SV=2"	"15"	"1"	"1"	"1"	"108"	"11.9"	"9.70"	"505.34"	""	"1"	""	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf15880"	"4731"	"ENSG00000160194"	"NDUFV3"	"A8K0M1; hsa:4731; J3KNX7; P56181; Q6FGD3; Q8WU60; Q9HCR5"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"42.3"	"40.4"	"44.6"	"36.0"	"38.4"	"40.4"	"48.5"	"59.8"	"120.4"	"192.5"	"268.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HBM1"	"Kinetochore protein Spc25 OS=Homo sapiens OX=9606 GN=SPC25 PE=1 SV=1"	"6"	"1"	"1"	"1"	"224"	"26.1"	"8.00"	"504.27"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf08234"	"57405"	"ENSG00000152253; ENSG00000277909"	"SPC25"	"A8K4X8; D3DPC0; hsa:57405; Q9HBM1"	""	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"6"	"0"	"18.2"	"17.5"	"18.9"	"14.4"	"20.6"	"25.9"	"24.1"	"26.3"	"54.6"	"56.4"	"59.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UH92"	"Max-like protein X OS=Homo sapiens OX=9606 GN=MLX PE=1 SV=2"	"2"	"1"	"2"	"1"	"298"	"33.3"	"8.06"	"503.63"	""	"1"	""	"other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00010"	"6945"	"ENSG00000108788"	"MLX"	"A8K2J3; B2RAV8; B2RD73; hsa:6945; Q53XM6; Q96FL2; Q9H2V0; Q9H2V1; Q9H2V2; Q9NXN3; Q9UH92"	"Nonalcoholic fatty liver disease"	"ChREBP activates metabolic gene expression"	"2"	"0"	"66.9"	"91.6"	"30.0"	"134.6"	"79.7"	"82.1"	"147.2"	"828.8"	"247.4"	"1216.8"	"228.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95926"	"Pre-mRNA-splicing factor SYF2 OS=Homo sapiens OX=9606 GN=SYF2 PE=1 SV=1"	"7"	"1"	"1"	"1"	"243"	"28.7"	"8.40"	"502.84"	""	"1"	""	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	""	"Pf08231"	"25949"	"ENSG00000117614"	"SYF2"	"hsa:25949; O95926; Q5TH73"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"8.9"	"13.4"	"10.7"	"7.0"	"6.0"	"9.8"	"11.0"	"9.8"	"7.7"	"11.1"	"17.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N3X1"	"Formin-binding protein 4 OS=Homo sapiens OX=9606 GN=FNBP4 PE=1 SV=3"	"1"	"1"	"1"	"1"	"1017"	"110.2"	"4.74"	"499.10"	""	"1"	""	""	"nucleus"	""	"Pf00397"	"23360"	"ENSG00000109920; ENSG00000285182"	"FNBP4"	"hsa:23360; Q8N3X1; Q9H985; Q9NT81; Q9Y2L7"	""	""	"0"	"0"	"31.5"	"23.3"	"24.0"	"21.2"	"21.0"	"26.2"	"27.9"	"30.0"	"31.2"	"38.2"	"37.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2I1"	"Nischarin OS=Homo sapiens OX=9606 GN=NISCH PE=1 SV=3"	"1"	"2"	"2"	"2"	"1504"	"166.5"	"5.14"	"496.19"	""	"2"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00787"	"11188"	"ENSG00000010322"	"NISCH"	"C9J245; hsa:11188; Q6PGP3; Q6PIB4; Q7L8M3; Q7Z2X6; Q9UES6; Q9UEU4; Q9UFW3; Q9Y2I1"	""	"RND3 GTPase cycle; RAC1 GTPase cycle; RND2 GTPase cycle"	"3"	"0"	"107.9"	"103.8"	"116.9"	"103.3"	"122.0"	"112.9"	"137.1"	"172.9"	"279.1"	"705.6"	"999.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BY32"	"Inosine triphosphate pyrophosphatase OS=Homo sapiens OX=9606 GN=ITPA PE=1 SV=2"	"6"	"1"	"1"	"1"	"194"	"21.4"	"5.66"	"484.88"	""	"1"	""	"cell organization and biogenesis;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01725"	"3704"	"ENSG00000125877"	"ITPA"	"A2A2N2; A4UIM5; B2BCH7; hsa:3704; O14878; Q5JWH4; Q9BY32; Q9BYN1; Q9BYX0; Q9H3H8"	""	"Purine catabolism; Ribavirin ADME"	"2"	"0"	"37.9"	"44.1"	"48.1"	"42.6"	"55.3"	"33.0"	"55.9"	"70.6"	"147.1"	"225.5"	"288.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75116"	"Rho-associated protein kinase 2 OS=Homo sapiens OX=9606 GN=ROCK2 PE=1 SV=4"	"1"	"2"	"2"	"1"	"1388"	"160.8"	"6.02"	"484.45"	""	"2"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;kinase activity;other molecular function"	"Pf00069, Pf08912"	"9475"	"ENSG00000134318"	"ROCK2"	"hsa:9475; O75116; Q53QZ0; Q53SJ7; Q9UQN5"	"Androgen receptor signaling pathway; MicroRNAs in cardiomyocyte hypertrophy; Integrin-mediated cell adhesion; Leptin signaling pathway; Pathogenic Escherichia coli infection; Spinal cord injury; Focal adhesion; Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Wnt signaling; Airway smooth muscle cell contraction; Regulation of actin cytoskeleton; GDNF signaling; G13 signaling pathway"	"Potential therapeutics for SARS; RHOC GTPase cycle; RHOA GTPase cycle; G alpha (12/13) signalling events; RHOB GTPase cycle; EPHB-mediated forward signaling; VEGFA-VEGFR2 Pathway; EPHA-mediated growth cone collapse; Sema4D induced cell migration and growth-cone collapse; RHO GTPases Activate ROCKs; RHOBTB1 GTPase cycle; RHOH GTPase cycle"	"27"	"0"	"79.5"	"110.9"	"114.9"	"69.8"	"96.2"	"95.5"	"117.2"	"168.6"	"291.3"	"486.7"	"686.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63000"	"Ras-related C3 botulinum toxin substrate 1 OS=Homo sapiens OX=9606 GN=RAC1 PE=1 SV=1"	"8"	"1"	"1"	"1"	"192"	"21.4"	"8.50"	"483.66"	""	"1"	""	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00071"	"5879"	"ENSG00000136238"	"RAC1"	"hsa:5879; O95501; P15154; P63000; Q3Y4D3; Q5JAA8; Q9BTB4"	"Androgen receptor signaling pathway; Nucleotide-binding oligomerization domain (NOD) pathway; Target of rapamycin signaling; Physiological and pathological hypertrophy of the heart; MicroRNAs in cardiomyocyte hypertrophy; Integrin-mediated cell adhesion; RANKL/RANK signaling pathway; Leptin signaling pathway; TNF-related weak inducer of apoptosis (TWEAK) signaling pathway; Prolactin signaling pathway; Microtubule cytoskeleton regulation; RalA downstream regulated genes; B cell receptor signaling pathway; TNF-alpha signaling pathway; AGE/RAGE pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Spinal cord injury; Alpha 6 beta 4 signaling pathway; Amyotrophic lateral sclerosis (ALS); Cardiac hypertrophic response; Focal adhesion; RAC1/PAK1/p38/MMP2 pathway; Wnt signaling pathway; IL6 signaling pathway; Hepatitis C and hepatocellular carcinoma; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Microglia pathogen phagocytosis pathway; Robo4 and VEGF signaling pathways crosstalk; p38 MAPK signaling pathway; PI3K-Akt signaling pathway; Chromosomal and microsatellite instability in colorectal cancer ; Ebola virus infection in host; Ras signaling; Pancreatic adenocarcinoma pathway; Wnt signaling; Ciliary landscape; EGF/EGFR signaling pathway; Nonalcoholic fatty liver disease; Hippo signaling regulation pathways; Leukocyte-intrinsic Hippo pathway functions; Neural crest cell migration during development; Neural crest cell migration in cancer; Gastrin signaling pathway; Melanoma; Netrin-UNC5B signaling pathway; Insulin signaling; CAMKK2 pathway; Opioid receptor pathways; Regulation of actin cytoskeleton; GDNF signaling; 2q13 copy number variation syndrome; 2q21.1 copy number variation syndrome; 2q37 copy number variation syndrome; G13 signaling pathway; Genetic causes of porto-sinusoidal vascular disease; TROP2 regulatory signaling; 13q12.12 copy number variation; Interferon type I signaling pathways; DNA damage response (only ATM dependent); Toll-like receptor signaling pathway"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; EPHB-mediated forward signaling; Neutrophil degranulation; FCERI mediated MAPK activation; Signaling by SCF-KIT; DAP12 signaling; PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases; EPH-ephrin mediated repulsion of cells; MAPK6/MAPK4 signaling; RAC1 GTPase cycle; NRAGE signals death through JNK; Translocation of SLC2A4 (GLUT4) to the plasma membrane; RHO GTPases activate IQGAPs; RHO GTPases Activate Formins; PIP3 activates AKT signaling; Constitutive Signaling by Aberrant PI3K in Cancer; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; DCC mediated attractive signaling; GPVI-mediated activation cascade; Ephrin signaling; Factors involved in megakaryocyte development and platelet production; RHO GTPases activate CIT; PCP/CE pathway; WNT5:FZD7-mediated leishmania damping; Sema3A PAK dependent Axon repulsion; SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion; Signal transduction by L1; RHO GTPases activate PKNs; RHO GTPases activate PAKs; DSCAM interactions; Azathioprine ADME; VEGFR2 mediated vascular permeability; Sema4D mediated inhibition of cell attachment and migration; Inactivation of CDC42 and RAC1; Activation of RAC1; CD28 dependent Vav1 pathway; Nef and signal transduction; RHO GTPases Activate NADPH Oxidases; NTRK2 activates RAC1; MET activates RAP1 and RAC1; Activation of RAC1 downstream of NMDARs; Activated NTRK2 signals through CDK5; RHO GTPases activate KTN1"	"108"	"0"	"14.5"	"21.8"	"15.9"	"10.2"	"16.6"	"18.0"	"19.7"	"31.1"	"71.3"	"126.0"	"176.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P45974"	"Ubiquitin carboxyl-terminal hydrolase 5 OS=Homo sapiens OX=9606 GN=USP5 PE=1 SV=2"	"1"	"1"	"1"	"1"	"858"	"95.7"	"5.03"	"480.69"	""	"1"	""	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle"	"other molecular function"	"Pf00443, Pf00627, Pf02148, Pf17807"	"8078"	"ENSG00000111667"	"USP5"	"D3DUS7; D3DUS8; hsa:8078; P45974; Q96J22"	"IL-18 signaling pathway"	"Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Ub-specific processing proteases"	"3"	"0"	"19.6"	"24.1"	"21.0"	"21.4"	"19.2"	"16.2"	"19.1"	"33.3"	"48.5"	"66.0"	"73.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HAF1"	"Chromatin modification-related protein MEAF6 OS=Homo sapiens OX=9606 GN=MEAF6 PE=1 SV=1"	"7"	"1"	"1"	"1"	"191"	"21.6"	"9.32"	"474.48"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf09340"	"64769"	"ENSG00000163875"	"MEAF6"	"B1AK64; hsa:64769; Q4F967; Q7Z311; Q86WE3; Q9HAF1"	""	"HATs acetylate histones; Regulation of TP53 Activity through Acetylation"	"2"	"0"	"16.4"	"10.7"	"13.2"	"11.7"	"8.5"	"10.9"	"13.6"	"22.3"	"23.9"	"20.4"	"27.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q10469"	"Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT2 PE=1 SV=1"	"4"	"1"	"1"	"1"	"447"	"51.5"	"8.76"	"464.04"	""	"1"	""	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf05060"	"4247"	"ENSG00000168282"	"MGAT2"	"B3KPC5; B3KQM0; hsa:4247; Q10469"	"N-glycan biosynthesis"	"Reactions specific to the complex N-glycan synthesis pathway; Maturation of spike protein; Defective MGAT2 causes CDG-2a"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99418"	"Cytohesin-2 OS=Homo sapiens OX=9606 GN=CYTH2 PE=1 SV=2"	"3"	"1"	"1"	"1"	"400"	"46.5"	"5.54"	"453.76"	""	"1"	""	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf01369"	"9266"	"ENSG00000105443"	"CYTH2"	"A8K8P0; hsa:9266; Q8IXY9; Q92958; Q99418"	"2q37 copy number variation syndrome"	"Intra-Golgi traffic"	"2"	"0"	"8.5"	"8.3"	"7.5"	"8.2"	"7.4"	"13.6"	"20.6"	"34.0"	"74.1"	"95.7"	"126.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30414"	"NK-tumor recognition protein OS=Homo sapiens OX=9606 GN=NKTR PE=1 SV=2"	"1"	"1"	"1"	"1"	"1462"	"165.6"	"9.99"	"448.33"	""	"1"	""	"protein metabolism;other metabolic processes"	"plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00160"	"4820"	"ENSG00000114857"	"NKTR"	"hsa:4820; P30414"	""	""	"0"	"0"	"119.6"	"95.5"	"130.6"	"112.0"	"110.8"	"131.0"	"143.5"	"149.2"	"210.2"	"337.1"	"485.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BRR8"	"G patch domain-containing protein 1 OS=Homo sapiens OX=9606 GN=GPATCH1 PE=1 SV=1"	"1"	"1"	"1"	"1"	"931"	"103.3"	"7.05"	"446.00"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf01585, Pf07713"	"55094"	"ENSG00000076650"	"GPATCH1"	"hsa:55094; Q8IZV6; Q8N3B7; Q9BRR8; Q9NW94"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"12.0"	"8.4"	"14.3"	"10.7"	"12.5"	"10.3"	"13.1"	"17.9"	"19.8"	"30.3"	"73.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94927"	"HAUS augmin-like complex subunit 5 OS=Homo sapiens OX=9606 GN=HAUS5 PE=1 SV=2"	"2"	"1"	"1"	"1"	"633"	"71.6"	"8.51"	"436.75"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton"	""	"Pf14817"	"23354"	"ENSG00000249115"	"HAUS5"	"B2RXK1; hsa:23354; O94927; Q6P2P7; Q7L3D5; Q96CT8"	""	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"7"	"0"	"40.8"	"45.5"	"51.5"	"41.3"	"58.9"	"55.3"	"65.5"	"63.7"	"136.2"	"221.0"	"304.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q4VC05"	"B-cell CLL/lymphoma 7 protein family member A OS=Homo sapiens OX=9606 GN=BCL7A PE=1 SV=1"	"5"	"1"	"1"	"1"	"210"	"22.8"	"5.14"	"430.60"	""	"1"	""	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	""	"Pf04714"	"605"	"ENSG00000110987; ENSG00000282873"	"BCL7A"	"B4DJN6; B7ZB21; hsa:605; Q13843; Q14CT7; Q4VC05"	""	""	"0"	"0"	"46.6"	"56.0"	"60.0"	"42.4"	"50.1"	"61.7"	"71.1"	"89.4"	"201.5"	"466.1"	"711.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q53H12"	"Acylglycerol kinase, mitochondrial OS=Homo sapiens OX=9606 GN=AGK PE=1 SV=2"	"3"	"1"	"1"	"1"	"422"	"47.1"	"8.09"	"429.89"	""	"1"	""	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;cytosol;mitochondrion;other cell component"	"kinase activity;other molecular function"	"Pf00781, Pf19712"	"55750"	"ENSG00000006530; ENSG00000262327"	"AGK"	"hsa:55750; Q53H12; Q75KN1; Q96GC3; Q9NP48"	""	"Signaling by BRAF and RAF1 fusions; Glycerophospholipid biosynthesis"	"2"	"0"	"45.0"	"38.9"	"53.5"	"39.9"	"42.7"	"38.3"	"56.8"	"70.0"	"167.0"	"245.3"	"302.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BV44"	"THUMP domain-containing protein 3 OS=Homo sapiens OX=9606 GN=THUMPD3 PE=1 SV=1"	"3"	"1"	"1"	"1"	"507"	"57.0"	"6.37"	"428.59"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01170, Pf02926"	"25917"	"ENSG00000134077"	"THUMPD3"	"hsa:25917; Q9BV44; Q9H8V6; Q9NVC1; Q9UFS3"	""	""	"0"	"0"	"6.2"	"5.6"	"3.7"	"6.5"	"2.5"	"5.1"	"8.6"	"16.9"	"22.8"	"54.8"	"101.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22694"	"cAMP-dependent protein kinase catalytic subunit beta OS=Homo sapiens OX=9606 GN=PRKACB PE=1 SV=2"	"3"	"1"	"1"	"1"	"351"	"40.6"	"8.78"	"428.05"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"5567"	"ENSG00000142875"	"PRKACB"	"B1APG4; B4DKB0; B4E2Q1; hsa:5567; P22694; Q14VH1; Q59GC0; Q5BNE9; Q5BNF0; Q5BNF1; Q5BNF2; Q5BNF3; Q5CZ92; Q5T1K3; Q7Z3M1; Q8IYR5; Q8IZQ0; Q96B09"	"AMP-activated protein kinase signaling; Dopamine metabolism; Common pathways underlying drug addiction; Myometrial relaxation and contraction pathways; G protein signaling pathways; MAPK signaling pathway; Cannabinoid receptor signaling; Chemokine signaling pathway; Lipid metabolism pathway; Ras signaling; Hedgehog signaling pathway; Thermogenesis; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; GPR143 in melanocytes and retinal pigment epithelium cells; Cardiomyocyte signaling pathways converging on Titin; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"FCGR3A-mediated IL10 synthesis; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; MAPK6/MAPK4 signaling; Triglyceride catabolism; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production; RET signaling; VEGFA-VEGFR2 Pathway; Factors involved in megakaryocyte development and platelet production; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Vasopressin regulates renal water homeostasis via Aquaporins; PKA activation; PKA activation in glucagon signalling; Regulation of glycolysis by fructose 2,6-bisphosphate metabolism; CD209 (DC-SIGN) signaling; Rap1 signalling; HDL assembly; DARPP-32 events; CREB1 phosphorylation through the activation of Adenylate Cyclase; ROBO receptors bind AKAP5; PKA-mediated phosphorylation of key metabolic factors"	"44"	"0"	"72.2"	"57.6"	"71.8"	"71.4"	"72.7"	"68.2"	"70.6"	"90.9"	"148.3"	"255.4"	"426.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6PIJ6"	"F-box only protein 38 OS=Homo sapiens OX=9606 GN=FBXO38 PE=1 SV=3"	"1"	"1"	"1"	"1"	"1188"	"133.9"	"6.33"	"425.86"	""	"1"	""	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf00646"	"81545"	"ENSG00000145868"	"FBXO38"	"hsa:81545; Q6PIJ6; Q6PK72; Q7Z2U0; Q86VN3; Q9BXY6; Q9H837; Q9HC40"	""	""	"0"	"0"	"3.0"	"3.9"	"2.5"	"5.1"	"3.4"	"1.5"	"5.5"	"7.3"	"11.4"	"44.7"	"115.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96SU4"	"Oxysterol-binding protein-related protein 9 OS=Homo sapiens OX=9606 GN=OSBPL9 PE=1 SV=2"	"2"	"1"	"1"	"1"	"736"	"83.1"	"6.18"	"424.35"	""	"1"	""	"other metabolic processes;transport"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf00169, Pf01237"	"114883"	"ENSG00000117859"	"OSBPL9"	"B1AKJ8; B3KPQ4; D3DQ31; hsa:114883; Q5TFC0; Q6IA67; Q86YQ3; Q8NB17; Q8TAS8; Q96SK4; Q96SU4; Q9H9X2"	""	"Synthesis of bile acids and bile salts"	"1"	"0"	"0.0"	"6.3"	"0.0"	"0.0"	"0.0"	"0.0"	"2.7"	"3.7"	"13.8"	"42.6"	"70.2"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NPL8"	"Complex I assembly factor TIMMDC1, mitochondrial OS=Homo sapiens OX=9606 GN=TIMMDC1 PE=1 SV=2"	"4"	"1"	"1"	"1"	"285"	"32.2"	"8.50"	"423.26"	""	"1"	""	""	"other membranes;mitochondrion;nucleus"	""	"Pf02466"	"51300"	"ENSG00000113845"	"TIMMDC1"	"D3DN81; hsa:51300; Q6IAJ7; Q6UWU6; Q9NPL8; Q9NPR3; Q9NPS5; Q9P0Y6"	""	"Complex I biogenesis"	"1"	"0"	"57.7"	"50.4"	"68.6"	"49.4"	"57.6"	"71.5"	"85.8"	"111.0"	"212.3"	"286.6"	"424.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75351"	"Vacuolar protein sorting-associated protein 4B OS=Homo sapiens OX=9606 GN=VPS4B PE=1 SV=2"	"3"	"1"	"1"	"1"	"444"	"49.3"	"7.23"	"417.40"	""	"1"	""	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00004, Pf04212, Pf09336, Pf17862"	"9525"	"ENSG00000119541"	"VPS4B"	"hsa:9525; O75351; Q69HW4; Q9GZS7"	""	"Budding and maturation of HIV virion; Endosomal Sorting Complex Required For Transport (ESCRT)"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A8K8P3"	"Protein SFI1 homolog OS=Homo sapiens OX=9606 GN=SFI1 PE=1 SV=2"	"1"	"1"	"1"	"1"	"1242"	"147.6"	"10.81"	"414.82"	""	"1"	""	""	"cytosol;cytoskeleton"	"other molecular function"	""	"9814"	"ENSG00000198089"	"SFI1"	"A1L373; A1L387; A2A2L2; A8K8P3; B1AKL9; B5MDB7; B7Z1V6; B7Z8G3; B7ZBE2; B7ZBE3; hsa:9814; O60289; Q2TAN8; Q5W1B5; Q86TK0; Q8N4U8; Q8N8C1; Q8WU14"	""	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"7"	"0"	"5.4"	"5.9"	"3.5"	"6.9"	"7.2"	"10.6"	"23.2"	"44.7"	"57.2"	"55.1"	"70.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y6X9"	"ATPase MORC2 OS=Homo sapiens OX=9606 GN=MORC2 PE=1 SV=2"	"1"	"1"	"1"	"1"	"1032"	"117.8"	"8.38"	"414.63"	""	"1"	""	"cell organization and biogenesis;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf07496, Pf13589, Pf17942"	"22880"	"ENSG00000133422"	"MORC2"	"B2RNB1; hsa:22880; Q9UF28; Q9Y6V2; Q9Y6X9"	""	"Fatty acyl-CoA biosynthesis"	"1"	"0"	"12.6"	"21.3"	"19.5"	"20.4"	"20.2"	"11.5"	"25.5"	"24.2"	"40.0"	"102.5"	"169.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14192"	"Four and a half LIM domains protein 2 OS=Homo sapiens OX=9606 GN=FHL2 PE=1 SV=3"	"4"	"1"	"1"	"1"	"279"	"32.2"	"7.55"	"412.90"	""	"1"	""	"developmental processes;other biological processes"	"cytoskeleton;nucleus"	"other molecular function"	"Pf00412"	"2274"	"ENSG00000115641"	"FHL2"	"hsa:2274; Q13229; Q13644; Q14192; Q2I5I4; Q5TM15; Q9P294"	"Androgen receptor signaling pathway; RANKL/RANK signaling pathway; Ectoderm differentiation; VEGFA-VEGFR2 signaling"	"PPARA activates gene expression"	"5"	"0"	"67.0"	"77.5"	"54.0"	"46.2"	"64.8"	"56.2"	"78.4"	"113.2"	"157.6"	"201.2"	"257.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q08945"	"FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1"	"2"	"1"	"1"	"1"	"709"	"81.0"	"6.87"	"399.51"	""	"1"	""	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00505, Pf03531, Pf08512, Pf17292"	"6749"	"ENSG00000149136"	"SSRP1"	"hsa:6749; Q08945; Q5BJG8"	""	"Regulation of TP53 Activity through Phosphorylation; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes"	"12"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92551"	"Inositol hexakisphosphate kinase 1 OS=Homo sapiens OX=9606 GN=IP6K1 PE=1 SV=3"	"3"	"1"	"1"	"1"	"441"	"50.2"	"7.24"	"393.78"	""	"1"	""	"other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf03770"	"9807"	"ENSG00000176095"	"IP6K1"	"A8K157; A8MUX4; hsa:9807; Q7L3I7; Q92551; Q96E38"	""	"Synthesis of pyrophosphates in the cytosol; Synthesis of IPs in the nucleus"	"2"	"0"	"3.8"	"6.9"	"6.2"	"4.7"	"7.4"	"8.3"	"15.9"	"33.3"	"61.7"	"59.7"	"73.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P78364"	"Polyhomeotic-like protein 1 OS=Homo sapiens OX=9606 GN=PHC1 PE=1 SV=3"	"2"	"1"	"1"	"1"	"1004"	"105.5"	"9.03"	"393.64"	""	"1"	""	"cell organization and biogenesis"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00536, Pf16616"	"1911"	"ENSG00000111752"	"PHC1"	"D3DUV4; hsa:1911; P78364; Q8WVM3; Q9BU63"	"Pleural mesothelioma"	"Oxidative Stress Induced Senescence; SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6"	"10"	"0"	"16.0"	"12.6"	"19.4"	"17.4"	"17.8"	"17.4"	"16.7"	"22.7"	"27.7"	"39.2"	"41.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BT92"	"Trichoplein keratin filament-binding protein OS=Homo sapiens OX=9606 GN=TCHP PE=1 SV=1"	"2"	"1"	"1"	"1"	"498"	"61.0"	"6.54"	"390.84"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;other cell component"	""	"Pf13868"	"84260"	"ENSG00000139437"	"TCHP"	"hsa:84260; Q8NAG0; Q9BT92"	""	""	"0"	"0"	"17.4"	"15.2"	"18.3"	"11.2"	"14.2"	"18.7"	"10.5"	"15.8"	"24.6"	"27.2"	"39.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKK9"	"ADP-sugar pyrophosphatase OS=Homo sapiens OX=9606 GN=NUDT5 PE=1 SV=1"	"7"	"1"	"1"	"1"	"219"	"24.3"	"4.94"	"390.68"	""	"1"	""	"cell organization and biogenesis;other metabolic processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00293"	"11164"	"ENSG00000165609"	"NUDT5"	"A8K516; hsa:11164; Q6IAG0; Q9UH49; Q9UKK9"	""	"Phosphate bond hydrolysis by NUDT proteins"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15051"	"IQ calmodulin-binding motif-containing protein 1 OS=Homo sapiens OX=9606 GN=IQCB1 PE=1 SV=1"	"2"	"1"	"1"	"1"	"598"	"68.9"	"9.10"	"390.19"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00612"	"9657"	"ENSG00000173226"	"IQCB1"	"hsa:9657; Q15051; Q3KS08; Q3KS09; Q5DKQ7; Q8NI79; Q9BS08"	"Ciliary landscape; Ciliopathies; Bardet-Biedl syndrome"	"Anchoring of the basal body to the plasma membrane"	"4"	"0"	"13.1"	"9.1"	"15.7"	"11.9"	"14.1"	"10.5"	"15.6"	"16.8"	"37.5"	"74.9"	"101.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P287"	"BRCA2 and CDKN1A-interacting protein OS=Homo sapiens OX=9606 GN=BCCIP PE=1 SV=1"	"5"	"1"	"1"	"1"	"314"	"36.0"	"4.61"	"375.07"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus"	"enzyme regulator activity;cytoskeletal activity"	"Pf13862"	"56647"	"ENSG00000107949"	"BCCIP"	"B3KP45; hsa:56647; Q8ND15; Q96GC4; Q9P287; Q9P288"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N556"	"Actin filament-associated protein 1 OS=Homo sapiens OX=9606 GN=AFAP1 PE=1 SV=2"	"1"	"1"	"1"	"1"	"730"	"80.7"	"8.68"	"366.56"	""	"1"	""	""	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00169"	"60312"	"ENSG00000196526"	"AFAP1"	"A8K442; B4DMU2; E9PDT7; hsa:60312; Q59EY5; Q8N556; Q9HBY1"	""	""	"0"	"0"	"61.3"	"48.0"	"55.5"	"46.2"	"49.8"	"51.2"	"62.3"	"65.5"	"113.3"	"152.6"	"177.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16762"	"Thiosulfate sulfurtransferase OS=Homo sapiens OX=9606 GN=TST PE=1 SV=4"	"4"	"1"	"1"	"1"	"297"	"33.4"	"7.25"	"366.48"	""	"1"	""	"other metabolic processes;transport;other biological processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00581"	"7263"	"ENSG00000128311"	"TST"	"B3KRM1; hsa:7263; Q16762; Q6IB06"	""	"Sulfide oxidation to sulfate"	"2"	"0"	"0.0"	"0.0"	"2.9"	"0.0"	"0.0"	"2.4"	"3.3"	"7.1"	"18.2"	"72.1"	"155.1"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15036"	"Sorting nexin-17 OS=Homo sapiens OX=9606 GN=SNX17 PE=1 SV=1"	"3"	"1"	"1"	"1"	"470"	"52.9"	"7.46"	"345.77"	""	"1"	""	"other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00787, Pf18116"	"9784"	"ENSG00000115234"	"SNX17"	"B4DQM7; hsa:9784; Q15036; Q53HN7; Q6IAS3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9ULX3"	"RNA-binding protein NOB1 OS=Homo sapiens OX=9606 GN=NOB1 PE=1 SV=1"	"4"	"1"	"1"	"1"	"412"	"46.6"	"7.18"	"342.97"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf08772, Pf15017, Pf17146"	"28987"	"ENSG00000141101"	"NOB1"	"hsa:28987; Q7L6B7; Q7M4M4; Q7Z4B5; Q9NWB0; Q9ULX3"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P2L0"	"WD repeat-containing protein 35 OS=Homo sapiens OX=9606 GN=WDR35 PE=1 SV=3"	"1"	"1"	"1"	"1"	"1181"	"133.5"	"6.38"	"340.61"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"cytoskeleton;other cell component"	""	"Pf12894"	"57539"	"ENSG00000118965"	"WDR35"	"B3KVI5; hsa:57539; Q4ZG01; Q8NE11; Q9P2L0"	"Intraflagellar transport proteins binding to dynein; Genes related to primary cilium development (based on CRISPR); Ciliopathies; Bardet-Biedl syndrome"	"Intraflagellar transport; Hedgehog 'off' state"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99576"	"TSC22 domain family protein 3 OS=Homo sapiens OX=9606 GN=TSC22D3 PE=1 SV=2"	"7"	"1"	"1"	"1"	"134"	"14.8"	"4.54"	"338.66"	""	"1"	""	"stress response;other biological processes"	"cytosol;nucleus"	""	"Pf01166"	"1831"	"ENSG00000157514"	"TSC22D3"	"hsa:1831; Q5H9S3; Q5JRI9; Q5JRJ2; Q6FIH6; Q8NAI1; Q8WVB9; Q99576; Q9UBN5; Q9UG13"	"Glucocorticoid receptor pathway; Nuclear receptors meta-pathway"	"Stimuli-sensing channels"	"3"	"0"	"27.4"	"27.4"	"33.8"	"27.2"	"37.6"	"31.2"	"43.6"	"61.8"	"87.6"	"139.5"	"166.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P34741"	"Syndecan-2 OS=Homo sapiens OX=9606 GN=SDC2 PE=1 SV=2"	"4"	"1"	"1"	"1"	"201"	"22.1"	"4.86"	"334.05"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01034"	"6383"	"ENSG00000169439"	"SDC2"	"B3KQA3; hsa:6383; P34741; Q6PIS6; Q9H6V1"	"miRNA targets in ECM and membrane receptors"	"EPHB-mediated forward signaling; Cell surface interactions at the vascular wall; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; A tetrasaccharide linker sequence is required for GAG synthesis; HS-GAG biosynthesis; HS-GAG degradation; Defective B4GALT7 causes EDS, progeroid type; Defective B3GAT3 causes JDSSDHD; Defective EXT2 causes exostoses 2; Defective EXT1 causes exostoses 1, TRPS2 and CHDS; Defective B3GALT6 causes EDSP2 and SEMDJL1; Attachment and Entry; Retinoid metabolism and transport; Syndecan interactions"	"16"	"0"	"16.9"	"20.5"	"15.8"	"15.3"	"16.6"	"21.4"	"27.2"	"28.2"	"37.8"	"63.0"	"95.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q69YQ0"	"Cytospin-A OS=Homo sapiens OX=9606 GN=SPECC1L PE=1 SV=2"	"1"	"1"	"1"	"1"	"1117"	"124.5"	"5.72"	"331.03"	""	"1"	""	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"34.6"	"33.7"	"37.8"	"33.5"	"33.5"	"30.4"	"50.1"	"48.3"	"93.2"	"146.8"	"185.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NVE5"	"Ubiquitin carboxyl-terminal hydrolase 40 OS=Homo sapiens OX=9606 GN=USP40 PE=1 SV=3"	"1"	"1"	"1"	"1"	"1235"	"140.0"	"5.67"	"326.28"	""	"1"	""	"protein metabolism;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf00443"	"55230"	"ENSG00000085982"	"USP40"	"hsa:55230; Q6NX38; Q70EL0; Q9NVE5"	"2q37 copy number variation syndrome"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H582"	"Zinc finger protein 644 OS=Homo sapiens OX=9606 GN=ZNF644 PE=1 SV=2"	"1"	"1"	"1"	"1"	"1327"	"149.5"	"8.16"	"326.11"	""	"1"	""	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	""	"84146"	"ENSG00000122482"	"ZNF644"	"A2RU71; hsa:84146; Q2TAM0; Q5TCC0; Q6BEP7; Q6P446; Q6PI06; Q7LG67; Q9H582; Q9ULJ9"	""	""	"0"	"0"	"31.2"	"32.5"	"44.2"	"34.4"	"34.7"	"28.0"	"41.1"	"43.0"	"46.8"	"53.0"	"57.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15460"	"Prolyl 4-hydroxylase subunit alpha-2 OS=Homo sapiens OX=9606 GN=P4HA2 PE=1 SV=1"	"2"	"1"	"1"	"1"	"535"	"60.9"	"5.71"	"322.67"	""	"1"	""	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf08336, Pf13640"	"8974"	"ENSG00000072682"	"P4HA2"	"D3DQ85; D3DQ86; hsa:8974; O15460; Q8WWN0"	"VEGFA-VEGFR2 signaling; Amino acid metabolism; Type I collagen synthesis in the context of osteogenesis imperfecta"	"Collagen biosynthesis and modifying enzymes"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13200"	"26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3"	"2"	"1"	"1"	"1"	"908"	"100.1"	"5.20"	"315.03"	""	"1"	""	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf01851, Pf17781, Pf18051"	"5708"	"ENSG00000175166"	"PSMD2"	"B4DX07; B4DXY1; E7EW34; E9PCS3; hsa:5708; Q12932; Q13200; Q15321; Q53XQ4; Q96I12"	"Proteasome degradation; Alzheimer's disease and miRNA effects; TNF-alpha signaling pathway; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"Ub-specific processing proteases; Antigen processing: Ubiquitination & Proteasome degradation; CDK-mediated phosphorylation and removal of Cdc6; SCF(Skp2)-mediated degradation of p27/p21; FCERI mediated NF-kB activation; Downstream TCR signaling; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Orc1 removal from chromatin; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"65"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q53GG5"	"PDZ and LIM domain protein 3 OS=Homo sapiens OX=9606 GN=PDLIM3 PE=1 SV=1"	"4"	"1"	"1"	"1"	"364"	"39.2"	"6.89"	"306.34"	""	"1"	""	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412, Pf00595, Pf15936"	"27295"	"ENSG00000154553"	"PDLIM3"	"B2R866; hsa:27295; O43590; O60439; O60440; Q53GG5; Q8N6Y6; Q9BVP4"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N4T8"	"Carbonyl reductase family member 4 OS=Homo sapiens OX=9606 GN=CBR4 PE=1 SV=3"	"3"	"1"	"1"	"1"	"237"	"25.3"	"9.33"	"300.62"	""	"1"	""	"cell organization and biogenesis;other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf13561"	"84869"	"ENSG00000145439"	"CBR4"	"hsa:84869; Q8N4T8; Q8WTW8; Q96K93"	""	"Fatty acyl-CoA biosynthesis"	"1"	"0"	"39.6"	"47.4"	"50.8"	"36.9"	"48.0"	"43.1"	"52.2"	"54.6"	"79.5"	"138.2"	"167.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96JC1"	"Vam6/Vps39-like protein OS=Homo sapiens OX=9606 GN=VPS39 PE=1 SV=2"	"1"	"1"	"1"	"1"	"886"	"101.7"	"6.99"	"299.34"	""	"1"	""	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;other cytoplasmic organelle;other cell component"	""	"Pf00780, Pf10366, Pf10367"	"23339"	"ENSG00000166887"	"VPS39"	"hsa:23339; O94869; Q71SQ6; Q7Z3V3; Q96B93; Q96JC1; Q96RM0"	"VEGFA-VEGFR2 signaling; Ebola virus infection in host; Perturbations to host-cell autophagy, induced by SARS-CoV-2 proteins"	"SARS-CoV-2 modulates autophagy"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TE76"	"MORC family CW-type zinc finger protein 4 OS=Homo sapiens OX=9606 GN=MORC4 PE=1 SV=2"	"1"	"1"	"1"	"1"	"937"	"106.3"	"7.46"	"296.11"	""	"1"	""	""	"nucleus"	"other molecular function"	"Pf07496, Pf13589, Pf17942"	"79710"	"ENSG00000133131"	"MORC4"	"A1YR23; A1YR24; H7BXF1; hsa:79710; Q5JUK7; Q8TE76; Q96MZ2; Q9HAI7"	""	""	"0"	"0"	"87.6"	"68.4"	"111.7"	"81.6"	"93.4"	"104.7"	"108.3"	"118.6"	"134.3"	"169.1"	"186.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N4C6"	"Ninein OS=Homo sapiens OX=9606 GN=NIN PE=1 SV=4"	"1"	"1"	"1"	"1"	"2090"	"243.1"	"5.03"	"290.67"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	""	"51199"	"ENSG00000100503"	"NIN"	"A6NDB8; B7WPA3; C9JSB6; C9JSG2; C9JXL2; hsa:51199; Q5BKU3; Q6P0P6; Q8N4C6; Q9BWU6; Q9C012; Q9C013; Q9C014; Q9H5I6; Q9HAT7; Q9HBY5; Q9HCK7; Q9UH61"	""	""	"0"	"0"	"19.0"	"20.1"	"25.8"	"21.0"	"25.7"	"22.2"	"21.2"	"29.5"	"93.5"	"231.4"	"374.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5VX52"	"Spermatogenesis-associated protein 1 OS=Homo sapiens OX=9606 GN=SPATA1 PE=2 SV=4"	"2"	"1"	"1"	"1"	"459"	"52.9"	"8.85"	"289.68"	""	"1"	""	""	"other cell component"	""	"Pf15743"	"100505741"	""	"SPATA1"	"A0A1W2PQB0; A0PJU9; hsa:100505741; Q0VDJ9; Q0VDK0; Q5VX52; Q6P386; Q9HAR4"	""	""	"0"	"0"	"135.4"	"117.3"	"136.3"	"123.1"	"128.1"	"136.3"	"155.7"	"164.6"	"329.7"	"576.9"	"858.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q53EZ4"	"Centrosomal protein of 55 kDa OS=Homo sapiens OX=9606 GN=CEP55 PE=1 SV=3"	"3"	"1"	"1"	"1"	"464"	"54.1"	"7.01"	"289.68"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"other molecular function"	"Pf12180"	"55165"	"ENSG00000138180"	"CEP55"	"B2RDG8; D3DR37; hsa:55165; Q32WF5; Q3MV20; Q53EZ4; Q5VY28; Q6N034; Q96H32; Q9NVS7"	""	""	"0"	"0"	"28.7"	"20.6"	"34.2"	"22.3"	"34.1"	"39.7"	"36.9"	"40.6"	"68.5"	"81.8"	"131.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86W56"	"Poly(ADP-ribose) glycohydrolase OS=Homo sapiens OX=9606 GN=PARG PE=1 SV=1"	"1"	"1"	"1"	"1"	"976"	"111.0"	"6.43"	"287.97"	""	"1"	""	"DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf05028"	"670; 8505"	"ENSG00000227345"	"PARG"	"A5YBK3; B2RC24; B4DIU5; B4DYR4; hsa:8505; I6RUV3; Q6E4P6; Q6E4P7; Q7Z742; Q86W56; Q9Y4W7"	"10q11.21q11.23 copy number variation syndrome"	"POLB-Dependent Long Patch Base Excision Repair"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14493"	"Histone RNA hairpin-binding protein OS=Homo sapiens OX=9606 GN=SLBP PE=1 SV=1"	"3"	"1"	"1"	"1"	"270"	"31.3"	"7.47"	"287.51"	""	"1"	""	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf15247"	"7884"	"ENSG00000163950"	"SLBP"	"B3KRJ5; hsa:7884; Q14493"	"8p23.1 copy number variation syndrome; 4p16.3 copy number variation"	"RNA Polymerase II Transcription Termination; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs; Transport of the SLBP Dependant Mature mRNA"	"5"	"0"	"100.8"	"99.8"	"84.6"	"94.9"	"103.7"	"100.0"	"123.8"	"154.6"	"236.4"	"382.3"	"471.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UQ84"	"Exonuclease 1 OS=Homo sapiens OX=9606 GN=EXO1 PE=1 SV=2"	"1"	"1"	"1"	"1"	"846"	"94.0"	"8.31"	"286.39"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00752, Pf00867"	"9156"	"ENSG00000174371"	"EXO1"	"hsa:9156; O60545; O75214; O75466; Q5T396; Q96IJ1; Q9UG38; Q9UNW0; Q9UQ84"	"DNA repair pathways, full network; DNA mismatch repair; Primary ovarian insufficiency"	"Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; Resolution of D-loop Structures through Holliday Junction Intermediates; Regulation of TP53 Activity through Phosphorylation; Presynaptic phase of homologous DNA pairing and strand exchange; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"19"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14646"	"Chromodomain-helicase-DNA-binding protein 1 OS=Homo sapiens OX=9606 GN=CHD1 PE=1 SV=2"	"1"	"1"	"1"	"1"	"1710"	"196.6"	"7.14"	"282.52"	""	"1"	""	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf00385, Pf13907, Pf18375"	"1105"	"ENSG00000153922"	"CHD1"	"hsa:1105; O14646; Q17RZ3"	""	"Estrogen-dependent gene expression"	"1"	"0"	"4.4"	"3.6"	"6.6"	"5.1"	"2.2"	"2.4"	"4.5"	"9.5"	"11.9"	"24.8"	"49.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5VTQ0"	"Tetratricopeptide repeat protein 39B OS=Homo sapiens OX=9606 GN=TTC39B PE=1 SV=4"	"2"	"1"	"1"	"1"	"682"	"76.9"	"7.39"	"281.33"	""	"1"	""	"other metabolic processes;other biological processes"	""	""	"Pf10300"	"158219"	"ENSG00000155158"	"TTC39B"	"A5PLN1; B4DQ10; B4DQX4; B4DW93; hsa:158219; Q5VTQ0; Q8IVR7; Q8IXZ6; Q8N267"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y478"	"5'-AMP-activated protein kinase subunit beta-1 OS=Homo sapiens OX=9606 GN=PRKAB1 PE=1 SV=4"	"6"	"1"	"1"	"1"	"270"	"30.4"	"6.40"	"271.87"	""	"1"	""	"protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf04739, Pf16561"	"5564"	"ENSG00000111725"	"PRKAB1"	"hsa:5564; Q9UBV0; Q9UE20; Q9UEX2; Q9Y478; Q9Y6V8"	"AMP-activated protein kinase signaling; Target of rapamycin signaling; Energy metabolism; Sterol regulatory element-binding proteins (SREBP) signaling; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; Angiopoietin-like protein 8 regulatory pathway; Leptin and adiponectin; Lipid metabolism pathway; Thermogenesis; Nonalcoholic fatty liver disease; Synaptic signaling pathways associated with autism spectrum disorder; Hippo signaling regulation pathways; 1q21.1 copy number variation syndrome; Autophagy; p53 transcriptional gene network; Pleural mesothelioma"	"Regulation of TP53 Activity through Phosphorylation; Macroautophagy; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Activation of AMPK downstream of NMDARs; TP53 Regulates Metabolic Genes; Energy dependent regulation of mTOR by LKB1-AMPK; Activation of PPARGC1A (PGC-1alpha) by phosphorylation; Lipophagy"	"24"	"0"	"12.2"	"10.9"	"15.3"	"13.0"	"15.6"	"10.0"	"14.2"	"18.9"	"40.0"	"79.3"	"111.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NI08"	"Nuclear receptor coactivator 7 OS=Homo sapiens OX=9606 GN=NCOA7 PE=1 SV=2"	"2"	"1"	"1"	"1"	"942"	"106.1"	"5.59"	"271.47"	""	"1"	""	"stress response;other biological processes"	"nucleus"	"other molecular function"	"Pf01476, Pf07534"	"135112"	"ENSG00000111912"	"NCOA7"	"B2RNS2; B7Z2C4; B9EH71; G8JL91; hsa:135112; Q3LID6; Q4G0V1; Q5TF95; Q6IPQ4; Q6NE83; Q86T89; Q8N1W4; Q8NI08"	"Aryl hydrocarbon receptor pathway"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WWK9"	"Cytoskeleton-associated protein 2 OS=Homo sapiens OX=9606 GN=CKAP2 PE=1 SV=1"	"1"	"1"	"1"	"1"	"683"	"76.9"	"9.41"	"270.06"	""	"1"	""	"cell cycle OR cell proliferation;other biological processes"	"cytoskeleton;other cell component"	""	"Pf15297"	"26586"	"ENSG00000136108"	"CKAP2"	"A2BDE0; A5YM58; B4DR35; E9PD90; hsa:26586; Q3KRA5; Q5VXB4; Q8IWV5; Q8IWV6; Q8WWK9; Q96FH9; Q9H012; Q9H0D0; Q9H988; Q9HC49; Q9NVG4"	""	""	"0"	"0"	"184.0"	"121.3"	"170.5"	"158.3"	"166.1"	"163.3"	"200.8"	"208.8"	"268.2"	"410.0"	"555.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q07699"	"Sodium channel subunit beta-1 OS=Homo sapiens OX=9606 GN=SCN1B PE=1 SV=1"	"4"	"1"	"1"	"1"	"218"	"24.7"	"4.89"	"269.65"	""	"1"	""	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;other cell component"	"transporter activity;other molecular function"	"Pf07686"	"6324"	"ENSG00000105711"	"SCN1B"	"hsa:6324; Q07699; Q5TZZ4; Q6TN97"	""	"Sensory perception of sweet, bitter, and umami (glutamate) taste; Interaction between L1 and Ankyrins; Phase 0 - rapid depolarisation"	"3"	"0"	"40.8"	"38.8"	"55.0"	"47.7"	"58.0"	"45.5"	"60.6"	"118.1"	"178.5"	"346.3"	"500.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NRM2"	"Zinc finger protein 277 OS=Homo sapiens OX=9606 GN=ZNF277 PE=1 SV=2"	"2"	"1"	"1"	"1"	"450"	"52.8"	"5.34"	"268.78"	""	"1"	""	"stress response;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf12756"	"11179"	"ENSG00000198839"	"ZNF277"	"hsa:11179; Q75MZ2; Q75MZ3; Q8WY14; Q9NRM2"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09543"	"2',3'-cyclic-nucleotide 3'-phosphodiesterase OS=Homo sapiens OX=9606 GN=CNP PE=1 SV=2"	"2"	"1"	"1"	"1"	"421"	"47.5"	"9.07"	"268.14"	""	"1"	""	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytoskeleton;mitochondrion;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05881, Pf13671"	"1267"	"ENSG00000173786"	"CNP"	"hsa:1267; P09543"	"Glial cell differentiation; MECP2 and associated Rett syndrome; VEGFA-VEGFR2 signaling; FGFR3 signaling in chondrocyte proliferation and terminal differentiation"	""	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NPA8"	"Transcription and mRNA export factor ENY2 OS=Homo sapiens OX=9606 GN=ENY2 PE=1 SV=1"	"7"	"1"	"1"	"1"	"101"	"11.5"	"9.33"	"266.97"	""	"1"	""	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf10163"	"56943"	"ENSG00000120533"	"ENY2"	"B2RE52; G3V117; hsa:56943; Q9NPA8"	""	"HATs acetylate histones"	"1"	"0"	"65.3"	"61.8"	"86.9"	"72.5"	"84.9"	"76.8"	"91.6"	"123.5"	"202.5"	"405.1"	"591.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P2W9"	"Syntaxin-18 OS=Homo sapiens OX=9606 GN=STX18 PE=1 SV=1"	"4"	"1"	"1"	"1"	"335"	"38.7"	"5.49"	"264.04"	""	"1"	""	"cell organization and biogenesis;transport;other biological processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf10496"	"53407"	"ENSG00000168818"	"STX18"	"hsa:53407; Q596L3; Q5TZP5; Q9P2W9"	""	"COPI-dependent Golgi-to-ER retrograde traffic"	"1"	"0"	"19.3"	"15.6"	"23.0"	"14.7"	"21.4"	"24.5"	"29.0"	"25.6"	"57.9"	"106.1"	"142.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UM54"	"Unconventional myosin-VI OS=Homo sapiens OX=9606 GN=MYO6 PE=1 SV=4"	"1"	"1"	"1"	"1"	"1294"	"149.6"	"8.53"	"261.14"	""	"1"	""	"cell organization and biogenesis;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00063, Pf16521"	"4646"	"ENSG00000196586"	"MYO6"	"A6H8V4; E1P540; hsa:4646; Q5TEM5; Q5TEM6; Q5TEM7; Q9BZZ7; Q9UEG2; Q9UM54"	"VEGFA-VEGFR2 signaling; Joubert syndrome"	"RHOU GTPase cycle; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle; Trafficking of AMPA receptors; Gap junction degradation"	"7"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NX07"	"tRNA selenocysteine 1-associated protein 1 OS=Homo sapiens OX=9606 GN=TRNAU1AP PE=1 SV=1"	"2"	"1"	"1"	"1"	"287"	"32.5"	"4.74"	"260.57"	""	"1"	""	"protein metabolism;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf17654"	"54952"	"ENSG00000180098"	"TRNAU1AP"	"hsa:54952; Q86SU7; Q9NX07"	""	""	"0"	"0"	"37.7"	"34.3"	"34.1"	"28.1"	"33.2"	"18.9"	"38.4"	"49.1"	"56.7"	"68.7"	"112.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y625"	"Glypican-6 OS=Homo sapiens OX=9606 GN=GPC6 PE=1 SV=1"	"1"	"1"	"1"	"1"	"555"	"62.7"	"5.41"	"260.21"	""	"1"	""	"other biological processes"	"non-structural extracellular;extracellular matrix;plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf01153"	"10082"	"ENSG00000183098"	"GPC6"	"A8K279; hsa:10082; Q96SG5; Q96SG8; Q9H1P4; Q9Y625"	"miR-509-3p alteration of YAP1/ECM axis"	"A tetrasaccharide linker sequence is required for GAG synthesis; HS-GAG biosynthesis; HS-GAG degradation; Defective B4GALT7 causes EDS, progeroid type; Defective B3GAT3 causes JDSSDHD; Defective EXT2 causes exostoses 2; Defective EXT1 causes exostoses 1, TRPS2 and CHDS; Defective B3GALT6 causes EDSP2 and SEMDJL1; Attachment and Entry; Retinoid metabolism and transport"	"11"	"0"	"24.3"	"27.4"	"23.0"	"13.8"	"22.3"	"11.4"	"26.8"	"45.7"	"47.5"	"104.8"	"159.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7L804"	"Rab11 family-interacting protein 2 OS=Homo sapiens OX=9606 GN=RAB11FIP2 PE=1 SV=1"	"3"	"1"	"1"	"1"	"512"	"58.2"	"9.32"	"259.64"	""	"1"	""	"cell-cell signaling;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00168, Pf09457"	"22841"	"ENSG00000107560"	"RAB11FIP2"	"A6NEI4; hsa:22841; Q3I768; Q7L804; Q9Y2F0"	""	"Vasopressin regulates renal water homeostasis via Aquaporins"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q07864"	"DNA polymerase epsilon catalytic subunit A OS=Homo sapiens OX=9606 GN=POLE PE=1 SV=5"	"0"	"1"	"1"	"1"	"2286"	"261.4"	"6.39"	"258.19"	""	"1"	""	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;developmental processes"	"plasma membrane;other membranes;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00136, Pf03104, Pf08490"	"5426"	"ENSG00000177084"	"POLE"	"hsa:5426; Q07864; Q13533; Q86VH9"	"Retinoblastoma gene in cancer; Pyrimidine metabolism; G1 to S cell cycle control; DNA replication; Base excision repair; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"Activation of the pre-replicative complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; DNA replication initiation; Gap-filling DNA repair synthesis and ligation in GG-NER"	"19"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y673"	"Dolichyl-phosphate beta-glucosyltransferase OS=Homo sapiens OX=9606 GN=ALG5 PE=1 SV=1"	"2"	"1"	"1"	"1"	"324"	"36.9"	"9.28"	"256.00"	""	"1"	""	"protein metabolism;other metabolic processes;developmental processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf00535"	"29880"	"ENSG00000120697"	"ALG5"	"B4DR37; hsa:29880; Q5TBA6; Q9Y673"	"N-glycan biosynthesis"	"Synthesis of dolichyl-phosphate-glucose"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q969Z3"	"Mitochondrial amidoxime reducing component 2 OS=Homo sapiens OX=9606 GN=MTARC2 PE=1 SV=1"	"2"	"1"	"1"	"1"	"335"	"38.0"	"9.16"	"255.54"	""	"1"	""	"other metabolic processes;stress response;other biological processes"	"other membranes;mitochondrion;other cytoplasmic organelle"	"other molecular function"	"Pf03473, Pf03476"	"54996"	"ENSG00000117791"	"MTARC2"	"B2D0R5; D3DTB3; hsa:54996; Q0JSK7; Q5VT67; Q5VXC7; Q7L317; Q969Z3; Q9H066; Q9NWU0"	""	"Phase I - Functionalization of compounds"	"1"	"0"	"29.8"	"28.3"	"42.2"	"27.6"	"38.0"	"31.6"	"39.8"	"57.9"	"86.7"	"201.4"	"293.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H3P7"	"Golgi resident protein GCP60 OS=Homo sapiens OX=9606 GN=ACBD3 PE=1 SV=4"	"1"	"1"	"1"	"1"	"528"	"60.6"	"5.06"	"254.56"	""	"1"	""	"other metabolic processes"	"other membranes;mitochondrion;ER/Golgi"	"other molecular function"	"Pf00887, Pf13897"	"64746"	"ENSG00000182827"	"ACBD3"	"B2RB29; hsa:64746; Q5VTJ0; Q6P9F1; Q8IZC5; Q8N4D6; Q9H3P7; Q9H6U3"	""	"Golgi Associated Vesicle Biogenesis"	"1"	"0"	"40.9"	"58.9"	"35.8"	"33.8"	"37.6"	"39.8"	"57.7"	"94.2"	"123.5"	"177.8"	"216.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6ZU35"	"Capping protein inhibiting regulator of actin dynamics OS=Homo sapiens OX=9606 GN=CRACD PE=1 SV=3"	"1"	"1"	"1"	"1"	"1233"	"136.7"	"5.60"	"254.42"	""	"1"	""	"cell organization and biogenesis;other biological processes"	"cytosol"	""	"Pf15262"	"57482"	"ENSG00000109265"	"CRACD"	"hsa:57482; Q6ZU35; Q9NTE2; Q9NTP8; Q9ULK9"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43709"	"Probable 18S rRNA (guanine-N(7))-methyltransferase OS=Homo sapiens OX=9606 GN=BUD23 PE=1 SV=2"	"2"	"1"	"1"	"1"	"281"	"31.9"	"8.73"	"253.41"	""	"1"	""	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf08241, Pf12589"	"114049"	"ENSG00000071462"	"BUD23"	"A8K501; C9K060; hsa:114049; O43709; Q96P12; Q9BQ58; Q9HBP9"	"7q11.23 copy number variation syndrome"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"3"	"0"	"200.4"	"189.9"	"202.9"	"185.2"	"204.8"	"223.2"	"240.7"	"275.4"	"528.9"	"684.1"	"570.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99856"	"AT-rich interactive domain-containing protein 3A OS=Homo sapiens OX=9606 GN=ARID3A PE=1 SV=2"	"2"	"1"	"1"	"1"	"593"	"62.9"	"4.91"	"253.16"	""	"1"	""	"other biological processes"	"other membranes;cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01388"	"1820"	"ENSG00000116017"	"ARID3A"	"hsa:1820; Q5I858; Q6P9C6; Q8IZA7; Q8N4Z3; Q99856"	""	"TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95671"	"Probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein OS=Homo sapiens OX=9606 GN=ASMTL PE=1 SV=3"	"2"	"1"	"1"	"1"	"621"	"68.8"	"6.07"	"252.56"	""	"1"	""	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf00891, Pf02545, Pf16864"	"8623"	"ENSG00000169093"	"ASMTL"	"B4DX75; F5GXH4; hsa:8623; J3JS33; O95671; Q5JQ53; Q8NBH5; Q96G02; Q9BUL6"	""	""	"0"	"0"	"3.3"	"6.6"	"5.9"	"5.6"	"6.1"	"3.7"	"2.9"	"5.9"	"16.0"	"36.0"	"47.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82909"	"28S ribosomal protein S36, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS36 PE=1 SV=2"	"12"	"1"	"1"	"1"	"103"	"11.5"	"9.99"	"252.42"	""	"1"	""	"other metabolic processes"	"other membranes;mitochondrion"	""	""	"92259"	"ENSG00000134056; ENSG00000278461"	"MRPS36"	"hsa:92259; P82909; Q9H2H4"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"19.3"	"19.5"	"18.5"	"26.5"	"26.0"	"25.3"	"21.8"	"35.7"	"102.6"	"237.9"	"274.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P0M9"	"39S ribosomal protein L27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL27 PE=1 SV=1"	"4"	"1"	"1"	"1"	"148"	"16.1"	"10.42"	"252.17"	""	"1"	""	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf01016"	"51264"	"ENSG00000108826"	"MRPL27"	"B2RE14; hsa:51264; Q9P0M9"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"87.1"	"119.9"	"68.6"	"68.5"	"83.8"	"92.6"	"110.4"	"162.2"	"229.9"	"542.4"	"1075.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96RT7"	"Gamma-tubulin complex component 6 OS=Homo sapiens OX=9606 GN=TUBGCP6 PE=1 SV=3"	"0"	"1"	"1"	"1"	"1819"	"200.4"	"6.32"	"251.33"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis"	"cytosol;cytoskeleton"	"cytoskeletal activity"	"Pf04130, Pf17681, Pf19340"	"85378"	"ENSG00000128159"	"TUBGCP6"	"hsa:85378; Q5JZ80; Q6PJ40; Q86YE9; Q96RT7; Q9BY91; Q9UGX3; Q9UGX4"	"Prader-Willi and Angelman syndrome; 15q11.2 copy number variation syndrome"	"Recruitment of NuMA to mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes"	"4"	"0"	"31.8"	"42.4"	"39.9"	"35.1"	"40.1"	"35.1"	"54.1"	"50.0"	"157.7"	"477.3"	"645.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NTM9"	"Copper homeostasis protein cutC homolog OS=Homo sapiens OX=9606 GN=CUTC PE=1 SV=1"	"2"	"1"	"1"	"1"	"273"	"29.3"	"8.18"	"251.13"	""	"1"	""	"cell organization and biogenesis;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf03932"	"51076"	"ENSG00000119929"	"CUTC"	"hsa:51076; Q5TCZ8; Q9NTM9; Q9Y321"	""	"Ion transport by P-type ATPases"	"1"	"0"	"98.9"	"80.9"	"71.4"	"75.9"	"91.9"	"86.1"	"98.2"	"118.9"	"195.9"	"253.3"	"276.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61244"	"Protein max OS=Homo sapiens OX=9606 GN=MAX PE=1 SV=1"	"4"	"1"	"1"	"1"	"160"	"18.3"	"6.30"	"251.05"	""	"1"	""	"cell organization and biogenesis;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00010"	"4149"	"ENSG00000125952"	"MAX"	"A6NH73; A8K265; A8K4G4; A8K824; hsa:4149; P25912; P52163; P61244; Q14803; Q96CY8"	"B cell receptor signaling pathway; Pathways affected in adenoid cystic carcinoma; MAPK signaling pathway; p38 MAPK signaling pathway; Small cell lung cancer; Pleural mesothelioma; 5q35 copy number variation"	"Transcriptional Regulation by E2F6; Cyclin E associated events during G1/S transition ; Transcription of E2F targets under negative control by DREAM complex; Cyclin A:Cdk2-associated events at S phase entry"	"11"	"0"	"145.8"	"119.6"	"131.1"	"131.5"	"128.4"	"134.2"	"142.3"	"180.6"	"285.4"	"697.2"	"1105.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q04721"	"Neurogenic locus notch homolog protein 2 OS=Homo sapiens OX=9606 GN=NOTCH2 PE=1 SV=3"	"0"	"1"	"1"	"1"	"2471"	"265.2"	"5.14"	"250.38"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00008, Pf00066, Pf06816, Pf07645, Pf07684, Pf12661, Pf12796"	"4853"	"ENSG00000134250"	"NOTCH2"	"hsa:4853; Q04721; Q5T3X7; Q99734; Q9H240"	"Neural crest differentiation; Notch signaling; Canonical and non-canonical Notch signaling; OSX and miRNAs in tooth development; Epithelial to mesenchymal transition in colorectal cancer; Breast cancer pathway; Head and neck squamous cell carcinoma; Osteoblast differentiation and related diseases; Genes controlling nephrogenesis; Primary ovarian insufficiency; Notch signaling pathway"	"NOTCH2 Activation and Transmission of Signal to the Nucleus; Pre-NOTCH Processing in Golgi; Pre-NOTCH Transcription and Translation; Notch-HLH transcription pathway; NOTCH2 intracellular domain regulates transcription; NOTCH4 Intracellular Domain Regulates Transcription; Pre-NOTCH Processing in the Endoplasmic Reticulum; Defective LFNG causes SCDO3"	"19"	"0"	"12.7"	"10.1"	"13.8"	"9.7"	"12.6"	"15.0"	"17.8"	"18.9"	"37.8"	"62.7"	"78.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6BDS2"	"UHRF1-binding protein 1 OS=Homo sapiens OX=9606 GN=UHRF1BP1 PE=1 SV=1"	"0"	"1"	"1"	"1"	"1440"	"159.4"	"6.14"	"249.95"	""	"1"	""	""	"other cytoplasmic organelle"	"other molecular function"	"Pf12624"	"54887"	"ENSG00000065060"	"BLTP3A"	"hsa:54887; Q6BDS2; Q9NXE0"	""	""	"0"	"0"	"35.2"	"38.2"	"39.1"	"27.3"	"39.6"	"39.2"	"48.5"	"44.7"	"60.5"	"80.5"	"112.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99698"	"Lysosomal-trafficking regulator OS=Homo sapiens OX=9606 GN=LYST PE=1 SV=3"	"0"	"1"	"1"	"1"	"3801"	"428.9"	"6.61"	"249.88"	""	"1"	""	"cell organization and biogenesis;stress response;transport;other biological processes"	"other membranes;cytosol;cytoskeleton"	"other molecular function"	"Pf00400, Pf02138, Pf14844"	"1130"	"ENSG00000143669"	"LYST"	"hsa:1130; O43274; Q5T2U9; Q96TD7; Q96TD8; Q99698; Q99709; Q9H133"	""	""	"0"	"0"	"125.6"	"108.8"	"117.1"	"111.5"	"138.8"	"115.4"	"123.5"	"125.4"	"147.0"	"296.0"	"499.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96IY1"	"Kinetochore-associated protein NSL1 homolog OS=Homo sapiens OX=9606 GN=NSL1 PE=1 SV=3"	"4"	"1"	"2"	"1"	"281"	"32.1"	"6.79"	"249.68"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf08641"	"25936"	"ENSG00000117697"	"NSL1"	"E7ETD5; hsa:25936; Q5SY75; Q96IY1; Q9H2M5; Q9NRN8; Q9Y415"	""	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"6"	"0"	"26.1"	"24.0"	"28.2"	"26.6"	"27.4"	"34.0"	"41.0"	"73.6"	"256.5"	"750.6"	"1487.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N1G1"	"RNA exonuclease 1 homolog OS=Homo sapiens OX=9606 GN=REXO1 PE=1 SV=3"	"1"	"1"	"1"	"1"	"1221"	"131.4"	"8.95"	"249.26"	""	"1"	""	""	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf15870"	"57455"	"ENSG00000079313"	"REXO1"	"hsa:57455; Q8N1G1; Q9ULT2"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H3R5"	"Centromere protein H OS=Homo sapiens OX=9606 GN=CENPH PE=1 SV=1"	"7"	"1"	"1"	"1"	"247"	"28.5"	"5.29"	"247.23"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf05837"	"64946"	"ENSG00000153044"	"CENPH"	"A8K3Y1; hsa:64946; Q9H3R5"	""	"RHO GTPases Activate Formins; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Deposition of new CENPA-containing nucleosomes at the centromere"	"7"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12802"	"A-kinase anchor protein 13 OS=Homo sapiens OX=9606 GN=AKAP13 PE=1 SV=2"	"0"	"1"	"1"	"1"	"2813"	"307.4"	"5.24"	"246.01"	""	"1"	""	"transport;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf00621, Pf10522"	"11214"	"ENSG00000170776"	"AKAP13"	"hsa:11214; Q12802; Q14572; Q59FP6; Q86W90; Q8WXQ6; Q96JP6; Q96P79; Q9Y5T0; Q9Y5T6"	"Glucocorticoid receptor pathway; Nuclear receptors meta-pathway; G protein signaling pathways"	"NRAGE signals death through JNK; RHOC GTPase cycle; RHOA GTPase cycle; G alpha (12/13) signalling events; RHOB GTPase cycle"	"8"	"0"	"44.8"	"40.3"	"40.2"	"37.8"	"47.0"	"41.8"	"49.7"	"46.0"	"81.8"	"140.6"	"165.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5VVY1"	"Alpha N-terminal protein methyltransferase 1B OS=Homo sapiens OX=9606 GN=METTL11B PE=1 SV=2"	"4"	"1"	"1"	"1"	"283"	"32.4"	"6.98"	"245.70"	""	"1"	""	"protein metabolism;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf05891"	"149281"	"ENSG00000203740"	"NTMT2"	"B2RXI0; hsa:149281; Q5VVY1"	""	""	"0"	"0"	"118.3"	"107.5"	"113.8"	"76.8"	"98.3"	"103.7"	"129.3"	"163.1"	"354.3"	"954.2"	"1753.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NPF5"	"DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1"	"2"	"1"	"1"	"1"	"467"	"53.0"	"9.50"	"244.87"	""	"1"	""	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf05499, Pf16282"	"55929"	"ENSG00000178028"	"DMAP1"	"A8K001; D3DPY8; hsa:55929; Q0JSM4; Q5TG41; Q7Z3H7; Q9H0S8; Q9NPF5; Q9P2C2"	""	"HATs acetylate histones"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49406"	"39S ribosomal protein L19, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL19 PE=1 SV=2"	"3"	"1"	"1"	"1"	"292"	"33.5"	"9.50"	"243.37"	""	"1"	""	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf01245"	"9801"	"ENSG00000115364"	"MRPL19"	"hsa:9801; P49406; Q53TX9; Q96Q52"	"Cytoplasmic ribosomal proteins"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"4"	"0"	"69.4"	"80.5"	"72.1"	"57.5"	"78.6"	"74.6"	"81.2"	"85.6"	"132.5"	"264.5"	"343.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBZ4"	"DNA-(apurinic or apyrimidinic site) lyase 2 OS=Homo sapiens OX=9606 GN=APEX2 PE=1 SV=1"	"2"	"1"	"1"	"1"	"518"	"57.4"	"8.29"	"242.09"	""	"1"	""	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03372, Pf06839"	"27301"	"ENSG00000169188"	"APEX2"	"hsa:27301; Q9UBZ4; Q9Y5X7"	"Base excision repair; DNA repair pathways, full network"	""	"2"	"0"	"24.5"	"21.0"	"25.9"	"23.5"	"27.9"	"19.4"	"25.8"	"31.6"	"41.5"	"62.2"	"58.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14975"	"Very long-chain acyl-CoA synthetase OS=Homo sapiens OX=9606 GN=SLC27A2 PE=1 SV=2"	"2"	"1"	"1"	"1"	"620"	"70.3"	"8.51"	"240.81"	""	"1"	""	"other metabolic processes;transport"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle"	"transporter activity;other molecular function"	"Pf00501, Pf13193"	"11001"	"ENSG00000140284"	"SLC27A2"	"A8K2J7; hsa:11001; O14975; Q53FY6; Q6PF09"	"PPAR signaling pathway; Fatty Acids and Lipoproteins Transport in Hepatocytes"	"Peroxisomal protein import; Neutrophil degranulation; Fatty acyl-CoA biosynthesis; Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol; Alpha-oxidation of phytanate; Synthesis of bile acids and bile salts via 24-hydroxycholesterol"	"8"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NPJ8"	"NTF2-related export protein 2 OS=Homo sapiens OX=9606 GN=NXT2 PE=1 SV=1"	"5"	"1"	"1"	"1"	"142"	"16.2"	"5.48"	"240.01"	""	"1"	""	"other metabolic processes;transport"	"cytosol;nucleus;other cell component"	""	"Pf02136"	"55916"	"ENSG00000101888"	"NXT2"	"D3DUY1; hsa:55916; Q0VAN8; Q5JYV5; Q5JYV6; Q5JYV7; Q9H8U0; Q9NPJ8; Q9NQ64; Q9NRL7; Q9Y3M4; Q9Y3M5"	""	""	"0"	"0"	"112.9"	"116.3"	"126.7"	"103.2"	"135.0"	"147.1"	"138.2"	"166.9"	"200.3"	"436.8"	"665.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WWV3"	"Reticulon-4-interacting protein 1, mitochondrial OS=Homo sapiens OX=9606 GN=RTN4IP1 PE=1 SV=2"	"3"	"1"	"1"	"1"	"396"	"43.6"	"9.11"	"237.96"	""	"1"	""	"developmental processes;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf08240, Pf13602"	"84816"	"ENSG00000130347"	"RTN4IP1"	"hsa:84816; Q8N9B3; Q8WWV3; Q8WZ66; Q9BRA4"	""	""	"0"	"0"	"3.6"	"6.6"	"4.0"	"3.9"	"4.4"	"7.3"	"9.5"	"7.9"	"25.8"	"45.6"	"59.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14202"	"Zinc finger MYM-type protein 3 OS=Homo sapiens OX=9606 GN=ZMYM3 PE=1 SV=2"	"1"	"1"	"1"	"1"	"1370"	"152.3"	"6.35"	"237.75"	""	"1"	""	"cell organization and biogenesis;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf06467, Pf12012"	"9203"	"ENSG00000147130"	"ZMYM3"	"D3DVV3; hsa:9203; O15089; Q14202; Q96E26"	"Orexin receptor pathway"	""	"1"	"0"	"6.9"	"5.7"	"5.6"	"5.8"	"7.5"	"7.0"	"9.6"	"10.3"	"19.9"	"48.5"	"55.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30307"	"M-phase inducer phosphatase 3 OS=Homo sapiens OX=9606 GN=CDC25C PE=1 SV=2"	"2"	"1"	"1"	"1"	"473"	"53.3"	"6.79"	"237.64"	""	"1"	""	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00581, Pf06617"	"995"	"ENSG00000158402"	"CDC25C"	"D3DQB8; hsa:995; P30307; Q96PL3; Q9H168; Q9H2E8; Q9H2E9; Q9H2F1"	"miRNA regulation of DNA damage response; Cell cycle; ATM signaling pathway; p53 transcriptional gene network; CCL18 signaling pathway; DNA damage response; Monoamine transport"	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain; Activation of ATR in response to replication stress; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RHO GTPases activate PKNs; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Cyclin A/B1/B2 associated events during G2/M transition; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models; Polo-like kinase mediated events"	"15"	"0"	"6.2"	"4.8"	"5.4"	"6.1"	"4.4"	"5.2"	"7.2"	"6.6"	"15.8"	"30.1"	"30.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75582"	"Ribosomal protein S6 kinase alpha-5 OS=Homo sapiens OX=9606 GN=RPS6KA5 PE=1 SV=1"	"1"	"1"	"1"	"1"	"802"	"89.8"	"7.11"	"236.32"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00433"	"9252"	"ENSG00000100784"	"RPS6KA5"	"B7Z2Y5; hsa:9252; O75582; O95316; Q96AF7"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; Interleukin-1 (IL-1) structural pathway; Bladder cancer; MAPK signaling pathway; ERK pathway in Huntington's disease; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; p38 MAPK signaling pathway; EGF/EGFR signaling pathway; Translation inhibitors in chronically activated PDGFRA cells; Insulin signaling; Pleural mesothelioma; Hippocampal synaptogenesis and neurogenesis; A network map of Macrophage-stimulating protein (MSP) signaling; Interferon type I signaling pathways; Serotonin HTR1 group and FOS pathway; Serotonin receptor 4/6/7 and NR3C signaling"	"Recycling pathway of L1; NCAM signaling for neurite out-growth; ERK/MAPK targets; CREB phosphorylation; CD209 (DC-SIGN) signaling"	"22"	"0"	"8.4"	"3.7"	"7.9"	"6.8"	"6.9"	"9.2"	"6.6"	"8.9"	"39.5"	"64.9"	"76.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6PK04"	"Coiled-coil domain-containing protein 137 OS=Homo sapiens OX=9606 GN=CCDC137 PE=1 SV=1"	"5"	"1"	"1"	"1"	"289"	"33.2"	"10.93"	"235.14"	""	"1"	""	""	"nucleus;other cell component"	""	""	"339230"	"ENSG00000185298"	"CCDC137"	"hsa:339230; Q6PK04"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UPN7"	"Serine/threonine-protein phosphatase 6 regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PPP6R1 PE=1 SV=5"	"1"	"1"	"1"	"1"	"881"	"96.7"	"4.55"	"234.55"	""	"1"	""	"other biological processes"	"cytosol;nucleus"	"enzyme regulator activity;other molecular function"	"Pf04499"	"22870"	"ENSG00000105063"	"PPP6R1"	"hsa:22870; Q2M2H3; Q504V2; Q6NVJ6; Q9BU97; Q9UPN7"	""	"COPII-mediated vesicle transport"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IYL3"	"UPF0688 protein C1orf174 OS=Homo sapiens OX=9606 GN=C1orf174 PE=1 SV=2"	"6"	"1"	"1"	"1"	"243"	"26.0"	"6.90"	"234.51"	""	"1"	""	""	"nucleus"	""	"Pf15772"	"339448"	"ENSG00000198912"	"C1orf174"	"A8K0C8; A8MUG9; hsa:339448; Q5SR20; Q6NX36; Q8IYL3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N5Y2"	"Male-specific lethal 3 homolog OS=Homo sapiens OX=9606 GN=MSL3 PE=1 SV=1"	"1"	"1"	"1"	"1"	"521"	"59.8"	"8.21"	"234.41"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05712, Pf11717"	"10943"	"ENSG00000005302"	"MSL3"	"A6NCU2; A6NHW8; A8K165; B4DUV8; B7Z227; hsa:10943; Q8N5Y2; Q9UG70; Q9Y5Z8"	""	"HATs acetylate histones"	"1"	"0"	"65.7"	"63.3"	"78.6"	"62.1"	"73.1"	"83.0"	"94.9"	"96.0"	"173.6"	"250.5"	"313.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BTK6"	"PAXIP1-associated glutamate-rich protein 1 OS=Homo sapiens OX=9606 GN=PAGR1 PE=1 SV=1"	"2"	"1"	"1"	"1"	"254"	"27.7"	"4.46"	"233.85"	""	"1"	""	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus"	"other molecular function"	"Pf15364"	"79447"	"ENSG00000280789"	"PAGR1"	"A2ICR6; hsa:79447; Q9BTK6"	"16p11.2 proximal deletion syndrome; Kleefstra syndrome"	"Formation of WDR5-containing histone-modifying complexes; Activation of anterior HOX genes in hindbrain development during early embryogenesis"	"4"	"0"	"91.1"	"95.6"	"109.6"	"90.5"	"114.2"	"114.4"	"107.7"	"109.6"	"156.0"	"222.2"	"294.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2K3"	"Myosin-15 OS=Homo sapiens OX=9606 GN=MYH15 PE=1 SV=5"	"0"	"1"	"1"	"1"	"1946"	"224.5"	"5.85"	"233.60"	""	"1"	""	""	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00063, Pf01576, Pf02736"	"22989"	"ENSG00000144821"	"MYH15"	"hsa:22989; Q9Y2K3"	""	""	"0"	"0"	"41.7"	"39.0"	"46.9"	"41.4"	"43.6"	"37.9"	"52.3"	"63.0"	"87.3"	"145.6"	"217.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08243"	"Asparagine synthetase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=ASNS PE=1 SV=4"	"1"	"1"	"1"	"1"	"561"	"64.3"	"6.86"	"233.57"	""	"1"	""	"other metabolic processes;stress response;other biological processes"	"cytosol"	"other molecular function"	"Pf00733, Pf13537"	"440"	"ENSG00000070669"	"ASNS"	"A4D1I8; B4DXZ1; B7ZAA9; D6W5R3; E9PCI3; E9PCX6; hsa:440; P08184; P08243; Q15666; Q549T9; Q96HD0"	"Photodynamic therapy-induced unfolded protein response; Amino acid metabolism"	"Aspartate and asparagine metabolism; Response of EIF2AK1 (HRI) to heme deficiency; ATF4 activates genes in response to endoplasmic reticulum  stress; Response of EIF2AK4 (GCN2) to amino acid deficiency"	"6"	"0"	"49.2"	"66.4"	"51.3"	"50.0"	"47.9"	"45.1"	"43.9"	"69.6"	"102.2"	"214.9"	"344.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35613"	"Basigin OS=Homo sapiens OX=9606 GN=BSG PE=1 SV=2"	"2"	"1"	"1"	"1"	"385"	"42.2"	"5.66"	"233.50"	""	"1"	""	"developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf13927"	"682"	"ENSG00000172270"	"BSG"	"A6NJW1; D3YLG5; hsa:682; P35613; Q7Z796; Q8IZL7"	"Matrix metalloproteinases; VEGFA-VEGFR2 signaling; IL-18 signaling pathway"	"Degradation of the extracellular matrix; Integrin cell surface interactions; Pyruvate metabolism; Aspirin ADME; Basigin interactions; Proton-coupled monocarboxylate transport; Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT)"	"10"	"0"	"162.4"	"204.7"	"162.7"	"164.0"	"165.0"	"136.5"	"160.5"	"227.5"	"380.6"	"686.7"	"845.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9ULJ8"	"Neurabin-1 OS=Homo sapiens OX=9606 GN=PPP1R9A PE=1 SV=2"	"1"	"1"	"1"	"1"	"1098"	"123.3"	"5.10"	"233.19"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf00595, Pf07647, Pf17817"	"55607"	"ENSG00000158528"	"PPP1R9A"	"A1L494; B2RWQ1; E9PCA0; E9PCK6; E9PDX1; F8W7J9; hsa:55607; O76059; Q9NXT2; Q9ULJ8"	"Perturbations to host-cell autophagy, induced by SARS-CoV-2 proteins"	""	"1"	"0"	"57.0"	"41.4"	"47.7"	"42.2"	"37.4"	"50.4"	"53.9"	"74.4"	"172.7"	"364.4"	"382.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z739"	"YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1"	"1"	"1"	"1"	"1"	"585"	"63.8"	"9.04"	"233.15"	""	"1"	""	"cell organization and biogenesis;other biological processes"	"cytosol;other cell component"	"translation activity;nucleic acid binding activity"	"Pf04146"	"253943"	"ENSG00000185728"	"YTHDF3"	"B3KXL4; hsa:253943; Q63Z37; Q659A3; Q7Z739"	""	""	"0"	"0"	"174.7"	"181.8"	"165.1"	"152.0"	"174.6"	"160.2"	"193.0"	"204.4"	"278.3"	"559.2"	"851.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q08209"	"Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform OS=Homo sapiens OX=9606 GN=PPP3CA PE=1 SV=1"	"2"	"1"	"1"	"1"	"521"	"58.7"	"5.86"	"233.11"	""	"1"	""	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00149"	"5530"	"ENSG00000138814"	"PPP3CA"	"A1A441; A8K3B7; A8W6Z7; A8W6Z8; B5BUA2; hsa:5530; Q08209; Q8TAW9"	"Physiological and pathological hypertrophy of the heart; Energy metabolism; MicroRNAs in cardiomyocyte hypertrophy; Alzheimer's disease and miRNA effects; Spinal cord injury; Amyotrophic lateral sclerosis (ALS); T cell receptor and co-stimulatory signaling; Cardiac hypertrophic response; Initiation of transcription and translation elongation at the HIV-1 LTR; G protein signaling pathways; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Mitochondrial gene expression; Serotonin and anxiety-related events; Serotonin and anxiety; Wnt signaling; Vitamin D in inflammatory diseases; Fragile X syndrome; Alzheimer's disease; Th17 cell differentiation pathway"	"FCERI mediated Ca+2 mobilization; CLEC7A (Dectin-1) induces NFAT activation; DARPP-32 events; Ca2+ pathway; Calcineurin activates NFAT"	"25"	"0"	"28.8"	"31.6"	"33.6"	"24.2"	"34.1"	"31.8"	"37.9"	"53.6"	"61.4"	"220.5"	"121.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N428"	"Polypeptide N-acetylgalactosaminyltransferase 16 OS=Homo sapiens OX=9606 GN=GALNT16 PE=1 SV=2"	"1"	"1"	"1"	"1"	"558"	"63.0"	"9.13"	"232.43"	""	"1"	""	"protein metabolism;other metabolic processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf00535, Pf00652"	"57452"	"ENSG00000100626"	"GALNT16"	"hsa:57452; Q4KMG3; Q58A55; Q8N428; Q9ULT9"	""	"O-linked glycosylation of mucins"	"1"	"0"	"36.9"	"44.7"	"24.5"	"41.8"	"38.2"	"35.5"	"37.5"	"158.0"	"97.9"	"269.6"	"123.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3S1"	"Serine/threonine-protein kinase WNK2 OS=Homo sapiens OX=9606 GN=WNK2 PE=1 SV=4"	"0"	"1"	"1"	"1"	"2297"	"242.5"	"6.13"	"232.32"	""	"1"	""	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf12202"	"65268"	"ENSG00000165238"	"WNK2"	"hsa:65268; Q5VWF1; Q5VWF2; Q8IY36; Q9C0A3; Q9H3P4; Q9Y3S1"	""	"Stimuli-sensing channels"	"1"	"0"	"9.9"	"8.9"	"8.5"	"7.2"	"13.0"	"6.7"	"13.9"	"11.4"	"24.4"	"106.5"	"195.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86UP3"	"Zinc finger homeobox protein 4 OS=Homo sapiens OX=9606 GN=ZFHX4 PE=1 SV=1"	"1"	"1"	"1"	"1"	"3567"	"393.5"	"6.37"	"232.29"	""	"1"	""	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00046, Pf00096, Pf12874"	"79776"	"ENSG00000091656"	"ZFHX4"	"G3V138; hsa:79776; Q18PS0; Q6ZN20; Q86UP3"	"Mesodermal commitment pathway; Ectoderm differentiation; Ectoderm differentiation"	""	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""