"Checked"	"Master"	"Accession"	"Description"	"Coverage [%]"	"# Peptides"	"# PSMs"	"# Unique Peptides"	"# AAs"	"MW [kDa]"	"calc. pI"	"Score MS Amanda 2.0: MS Amanda 2.0"	"Score Sequest HT: Sequest HT"	"# Peptides (by Search Engine): MS Amanda 2.0"	"# Peptides (by Search Engine): Sequest HT"	"Biological Process"	"Cellular Component"	"Molecular Function"	"Pfam IDs"	"Entrez Gene ID"	"Ensembl Gene ID"	"Gene Symbol"	"Gene ID"	"Reactome Pathways"	"WikiPathways"	"# Protein Pathway Groups"	"# Razor Peptides"	"Abundances (Grouped): 126"	"Abundances (Grouped): 127N"	"Abundances (Grouped): 127C"	"Abundances (Grouped): 128N"	"Abundances (Grouped): 128C"	"Abundances (Grouped): 129N"	"Abundances (Grouped): 129C"	"Abundances (Grouped): 130N"	"Abundances (Grouped): 130C"	"Abundances (Grouped): 131N"	"Abundances (Grouped): 131C"	"Abundances (Grouped) CV [%]: 126"	"Abundances (Grouped) CV [%]: 127N"	"Abundances (Grouped) CV [%]: 127C"	"Abundances (Grouped) CV [%]: 128N"	"Abundances (Grouped) CV [%]: 128C"	"Abundances (Grouped) CV [%]: 129N"	"Abundances (Grouped) CV [%]: 129C"	"Abundances (Grouped) CV [%]: 130N"	"Abundances (Grouped) CV [%]: 130C"	"Abundances (Grouped) CV [%]: 131N"	"Abundances (Grouped) CV [%]: 131C"	"Found in Sample: F25: 126, Sample"	"Found in Sample: F25: 127N, Sample"	"Found in Sample: F25: 127C, Sample"	"Found in Sample: F25: 128N, Sample"	"Found in Sample: F25: 128C, Sample"	"Found in Sample: F25: 129N, Sample"	"Found in Sample: F25: 129C, Sample"	"Found in Sample: F25: 130N, Sample"	"Found in Sample: F25: 130C, Sample"	"Found in Sample: F25: 131N, Sample"	"Found in Sample: F25: 131C, Sample"	"# Protein Groups"	"Modifications"
"False"	"IsMasterProtein"	"P08238"	"Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4"	"56"	"51"	"189"	"30"	"724"	"83.2"	"5.03"	"37426.36"	"367.50"	"45"	"44"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00183, Pf02518"	"3326"	"ENSG00000096384"	"HSP90AB1"	"B2R5P0; hsa:3326; P08238; Q5T9W7; Q9NQW0; Q9NTK6"	"Regulation of actin dynamics for phagocytic cup formation; Neutrophil degranulation; Potential therapeutics for SARS; The role of GTSE1 in G2/M progression after G2 checkpoint; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Aryl hydrocarbon receptor signalling; Estrogen-dependent gene expression; Sema3A PAK dependent Axon repulsion; DDX58/IFIH1-mediated induction of interferon-alpha/beta; The NLRP3 inflammasome; Purinergic signaling in leishmaniasis infection; RHOBTB2 GTPase cycle; Chaperone Mediated Autophagy; HSF1 activation; Attenuation phase; Uptake and function of diphtheria toxin"	"Nuclear receptors meta-pathway; NRF2 pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway"	"23"	"27"	"8117.9"	"10459.9"	"38411.0"	"9309.8"	"7570.7"	"5716.4"	"41400.4"	"4021.0"	"5152.6"	"4137.9"	"4108.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04264"	"Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6"	"49"	"45"	"170"	"38"	"644"	"66.0"	"8.12"	"30980.89"	"315.29"	"38"	"42"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"bone, tooth or skin structural activity;other molecular function"	"Pf00038, Pf16208, Pf16210"	"3848"	"ENSG00000167768"	"KRT1"	"B2RA01; hsa:3848; P04264; P85925; P86104; Q14720; Q6GSJ0; Q9H298"	"Formation of the cornified envelope; Neutrophil degranulation"	"Corticotropin-releasing hormone signaling pathway"	"4"	"9"	"50534.5"	"21362.7"	"19231.9"	"10939.2"	"3967.6"	"4039.0"	"11495.4"	"5004.6"	"2118.0"	"1911.5"	"2768.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07900"	"Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5"	"49"	"44"	"145"	"22"	"732"	"84.6"	"5.02"	"28574.15"	"277.53"	"39"	"35"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"non-structural extracellular;extracellular matrix;plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00183, Pf02518"	"3320"	"ENSG00000080824"	"HSP90AA1"	"A8K500; B3KPJ9; hsa:3320; P07900; Q2PP14; Q5CAQ6; Q5CAQ7; Q9BVQ5"	"Neutrophil degranulation; Regulation of actin dynamics for phagocytic cup formation; Potential therapeutics for SARS; The role of GTSE1 in G2/M progression after G2 checkpoint; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Recruitment of NuMA to mitotic centrosomes; Aggrephagy; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Extra-nuclear estrogen signaling; vRNP Assembly; Estrogen-dependent gene expression; Regulation of necroptotic cell death; Interleukin-4 and Interleukin-13 signaling; Downregulation of ERBB2 signaling; Signaling by ERBB2 KD Mutants; Signaling by ERBB2 TMD/JMD mutants; Sema3A PAK dependent Axon repulsion; DDX58/IFIH1-mediated induction of interferon-alpha/beta; PIWI-interacting RNA (piRNA) biogenesis; VEGFR2 mediated vascular permeability; RHOBTB2 GTPase cycle; Chaperone Mediated Autophagy; HSF1 activation; Attenuation phase; eNOS activation; Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation; Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; Constitutive Signaling by EGFRvIII; Signaling by ERBB2 ECD mutants; Uptake and function of diphtheria toxin; Constitutive Signaling by Overexpressed ERBB2; Scavenging by Class F Receptors; Drug-mediated inhibition of ERBB2 signaling; Resistance of ERBB2 KD mutants to trastuzumab; Resistance of ERBB2 KD mutants to sapitinib; Resistance of ERBB2 KD mutants to tesevatinib; Resistance of ERBB2 KD mutants to neratinib; Resistance of ERBB2 KD mutants to osimertinib; Resistance of ERBB2 KD mutants to afatinib; Resistance of ERBB2 KD mutants to AEE788; Resistance of ERBB2 KD mutants to lapatinib; Drug resistance in ERBB2 TMD/JMD mutants"	"Nucleotide-binding oligomerization domain (NOD) pathway; TNF-alpha signaling pathway; Corticotropin-releasing hormone signaling pathway; Aryl hydrocarbon receptor pathway; Ebstein-Barr virus LMP1 signaling; Aryl hydrocarbon receptor pathway; Constitutive androstane receptor pathway; Pregnane X receptor pathway; Glucocorticoid receptor pathway; Nuclear receptors meta-pathway; NRF2 pathway; VEGFA-VEGFR2 signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Th17 cell differentiation pathway"	"67"	"2"	"2960.4"	"3562.7"	"16406.5"	"3499.0"	"2494.4"	"1737.1"	"16314.4"	"1461.9"	"1936.5"	"1521.2"	"1435.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14618"	"Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4"	"74"	"38"	"118"	"38"	"531"	"57.9"	"7.84"	"23110.33"	"261.10"	"28"	"33"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00224, Pf02887"	"5315"	"ENSG00000067225"	"PKM"	"A6NFK3; B2R5N8; B3KRY0; B4DFX8; B4DUU6; hsa:5315; P14618; P14786; Q53GK4; Q96E76; Q9BWB5; Q9UCV6; Q9UPF2"	"Neutrophil degranulation"	"Photodynamic therapy-induced HIF-1 survival signaling; Amino acid metabolism; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Aerobic glycolysis; Glycolysis in senescence; Glucose metabolism in triple-negative breast cancer cells; Glycolysis and gluconeogenesis"	"9"	"0"	"3884.4"	"4761.2"	"14997.3"	"4757.6"	"4122.9"	"3664.6"	"18265.9"	"3050.6"	"4744.6"	"4018.2"	"5309.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11142"	"Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1"	"59"	"43"	"137"	"35"	"646"	"70.9"	"5.52"	"26114.35"	"229.96"	"39"	"42"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00012"	"3312"	"ENSG00000109971"	"HSPA8"	"hsa:3312; P11142; Q9H3R6"	"AUF1 (hnRNP D0) binds and destabilizes mRNA; Neutrophil degranulation; Golgi Associated Vesicle Biogenesis; Clathrin-mediated endocytosis; Late endosomal microautophagy; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Regulation of HSF1-mediated heat shock response; Lysosome Vesicle Biogenesis; mRNA Splicing - Major Pathway; CHL1 interactions; Interleukin-4 and Interleukin-13 signaling; GABA synthesis, release, reuptake and degradation; Lipophagy; Chaperone Mediated Autophagy; Protein methylation; Attenuation phase"	"Parkin-ubiquitin proteasomal system pathway; MAPK signaling pathway; Exercise-induced circadian regulation; Measles virus infection; Opioid receptor pathways; Extrafollicular and follicular B cell activation by SARS-CoV-2; 1p36 copy number variation syndrome"	"24"	"2"	"5718.8"	"6686.0"	"20671.3"	"7693.1"	"5872.7"	"4946.0"	"27527.3"	"4277.1"	"5841.1"	"4632.7"	"4723.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13639"	"Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4"	"58"	"55"	"131"	"53"	"858"	"95.3"	"6.83"	"26406.36"	"225.66"	"48"	"44"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00009, Pf00679, Pf03144, Pf03764, Pf14492"	"1938"	"ENSG00000167658"	"EEF2"	"A0A384N6H1; B2RMP5; D6W618; hsa:1938; P13639; Q58J86"	"Neutrophil degranulation; Protein methylation; Uptake and function of diphtheria toxin; Peptide chain elongation; Synthesis of diphthamide-EEF2"	"Translation factors; AMP-activated protein kinase signaling; Brain-derived neurotrophic factor (BDNF) signaling pathway; IL-18 signaling pathway"	"9"	"2"	"7406.8"	"7491.4"	"26626.7"	"8779.8"	"6472.0"	"5247.4"	"24281.4"	"3034.6"	"5010.7"	"4492.6"	"5588.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35527"	"Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3"	"51"	"31"	"108"	"30"	"623"	"62.0"	"5.24"	"18488.31"	"215.53"	"23"	"30"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton"	"cytoskeletal activity"	"Pf00038"	"3857"	"ENSG00000171403"	"KRT9"	"hsa:3857; O00109; P35527; Q0IJ47; Q14665"	"Formation of the cornified envelope"	""	"2"	"2"	"36179.7"	"13106.9"	"14025.3"	"12055.9"	"3649.3"	"3193.0"	"10018.8"	"4588.6"	"1658.0"	"1667.8"	"2957.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14204"	"Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5"	"17"	"61"	"114"	"60"	"4646"	"532.1"	"6.40"	"20951.82"	"214.71"	"53"	"56"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03028, Pf08385, Pf08393, Pf12774, Pf12775, Pf12777, Pf12780, Pf12781, Pf17852, Pf18198, Pf18199"	"1778"	"ENSG00000197102"	"DYNC1H1"	"B0I1R0; hsa:1778; Q14204; Q6DKQ7; Q8WU28; Q92814; Q9Y4G5"	"Neutrophil degranulation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; HCMV Early Events; COPI-independent Golgi-to-ER retrograde traffic; MHC class II antigen presentation; Recruitment of NuMA to mitotic centrosomes; COPI-mediated anterograde transport; Aggrephagy; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein"	"22"	"1"	"4091.7"	"4054.3"	"14472.5"	"3547.8"	"3151.9"	"2328.0"	"12754.3"	"1828.9"	"2810.9"	"2333.7"	"2333.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P0DMV9"	"Heat shock 70 kDa protein 1B OS=Homo sapiens OX=9606 GN=HSPA1B PE=1 SV=1"	"73"	"45"	"108"	"39"	"641"	"70.0"	"5.66"	"18369.21"	"213.13"	"33"	"41"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00012"	"3303; 3304"	"ENSG00000204388; ENSG00000212866; ENSG00000224501; ENSG00000231555; ENSG00000232804"	"HSPA1B"	"B4E3B6; hsa:3303; hsa:3304; P08107; P0DMV9; P19790; Q5JQI4; Q5SP17; Q9UQL9; Q9UQM0"	"Regulation of HSF1-mediated heat shock response; Neutrophil degranulation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Attenuation phase"	"Apoptosis modulation and signaling; Parkin-ubiquitin proteasomal system pathway; MAPK signaling pathway; Apoptosis modulation by HSP70; VEGFA-VEGFR2 signaling; Measles virus infection; CKAP4 signaling pathway map"	"12"	"8"	"6128.2"	"7915.9"	"23686.1"	"8805.3"	"6936.9"	"6257.8"	"30469.7"	"4265.8"	"6228.5"	"5002.0"	"4934.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22102"	"Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1"	"49"	"46"	"93"	"46"	"1010"	"107.7"	"6.70"	"17646.16"	"206.44"	"37"	"43"	"other metabolic processes;developmental processes;other biological processes"	"cytosol"	"other molecular function"	"Pf00551, Pf00586, Pf01071, Pf02769, Pf02843, Pf02844"	"2618"	"ENSG00000159131; ENSG00000262473"	"GART"	"A8K945; A8KA32; D3DSF3; D3DSF4; hsa:2618; O14659; P22102; Q52M77"	"Purine ribonucleoside monophosphate biosynthesis"	"Folate metabolism; One-carbon metabolism; Metabolic reprogramming in colon cancer"	"4"	"0"	"1441.4"	"1540.5"	"5137.7"	"1513.3"	"1394.4"	"1183.3"	"7182.1"	"3804.9"	"12223.9"	"16109.0"	"20673.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13645"	"Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6"	"45"	"30"	"106"	"24"	"584"	"58.8"	"5.21"	"18901.12"	"200.61"	"25"	"28"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;cytosol;cytoskeleton;other cell component"	"bone, tooth or skin structural activity;other molecular function"	"Pf00038"	"3858"	"ENSG00000186395"	"KRT10"	"hsa:3858; P13645; Q14664; Q8N175"	"Formation of the cornified envelope"	""	"2"	"9"	"29086.8"	"14082.6"	"8630.7"	"2408.9"	"1449.2"	"1704.7"	"4558.0"	"1851.4"	"1020.2"	"875.2"	"1104.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35908"	"Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2"	"52"	"36"	"104"	"26"	"639"	"65.4"	"8.00"	"19536.95"	"182.87"	"34"	"34"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;cytosol;cytoskeleton;other cell component"	"bone, tooth or skin structural activity;cytoskeletal activity"	"Pf00038, Pf16208"	"3849"	"ENSG00000172867"	"KRT2"	"hsa:3849; P35908; Q4VAQ2"	"Formation of the cornified envelope"	""	"2"	"9"	"38216.6"	"16077.4"	"9640.8"	"2645.2"	"1970.9"	"1761.6"	"5237.7"	"2157.0"	"1268.0"	"1086.8"	"1345.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P10809"	"60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2"	"56"	"39"	"99"	"39"	"573"	"61.0"	"5.87"	"20537.96"	"176.25"	"36"	"35"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00118"	"3329"	"ENSG00000144381"	"HSPD1"	"B2R5M6; B7Z712; hsa:3329; P10809; Q38L19; Q9UCR6"	"Mitochondrial protein import; TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"	"Apoptosis-related network due to altered Notch3 in ovarian cancer; Sudden infant death syndrome (SIDS) susceptibility pathways"	"4"	"0"	"4445.1"	"4859.9"	"28494.7"	"4736.0"	"3581.8"	"2682.1"	"32553.2"	"1832.5"	"2348.5"	"1907.1"	"1922.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P68371"	"Tubulin beta-4B chain OS=Homo sapiens OX=9606 GN=TUBB4B PE=1 SV=1"	"75"	"27"	"97"	"5"	"445"	"49.8"	"4.89"	"20421.60"	"174.84"	"23"	"26"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response"	"non-structural extracellular;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00091, Pf03953"	"10383"	"ENSG00000188229"	"TUBB4B"	"A2BFA2; hsa:10383; P05217; P68371"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Neutrophil degranulation; HCMV Early Events; COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport; Intraflagellar transport; Recycling pathway of L1; The role of GTSE1 in G2/M progression after G2 checkpoint; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane; Gap junction assembly; MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Formation of tubulin folding intermediates by CCT/TriC; Post-chaperonin tubulin folding pathway; RHO GTPases activate IQGAPs; COPI-independent Golgi-to-ER retrograde traffic; Carboxyterminal post-translational modifications of tubulin; Assembly and cell surface presentation of NMDA receptors; Activation of AMPK downstream of NMDARs; Aggrephagy; Sealing of the nuclear envelope (NE) by ESCRT-III; Kinesins; Prefoldin mediated transfer of substrate  to CCT/TriC; Hedgehog 'off' state"	"Alzheimer's disease and miRNA effects; Pathogenic Escherichia coli infection; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"41"	"1"	"539.6"	"551.9"	"1681.5"	"501.5"	"463.9"	"372.2"	"1835.0"	"298.5"	"401.3"	"306.3"	"315.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07437"	"Tubulin beta chain OS=Homo sapiens OX=9606 GN=TUBB PE=1 SV=2"	"75"	"27"	"96"	"5"	"444"	"49.6"	"4.89"	"20749.87"	"174.09"	"23"	"26"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;other biological processes"	"non-structural extracellular;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00091, Pf03953"	"203068"	"ENSG00000183311; ENSG00000196230; ENSG00000224156; ENSG00000227739; ENSG00000229684; ENSG00000232421; ENSG00000232575; ENSG00000235067"	"TUBB"	"hsa:203068; P05218; P07437; Q8WUC1; Q9CY33"	"Potential therapeutics for SARS; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Neutrophil degranulation"	"Alzheimer's disease and miRNA effects; Pathogenic Escherichia coli infection; Parkin-ubiquitin proteasomal system pathway; Opioid receptor pathways; Alzheimer's disease"	"14"	"33"	"2947.6"	"3057.7"	"11976.2"	"2729.1"	"2397.3"	"1798.9"	"13444.3"	"1337.0"	"1845.5"	"1392.0"	"1402.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P68363"	"Tubulin alpha-1B chain OS=Homo sapiens OX=9606 GN=TUBA1B PE=1 SV=1"	"55"	"23"	"83"	"3"	"451"	"50.1"	"5.06"	"14098.77"	"170.12"	"18"	"22"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00091, Pf03953"	"10376"	"ENSG00000123416"	"TUBA1B"	"hsa:10376; P04687; P05209; P68363; Q27I68; Q8WU19"	"Recruitment of NuMA to mitotic centrosomes; Recycling pathway of L1; COPI-dependent Golgi-to-ER retrograde traffic; MHC class II antigen presentation; Kinesins; Hedgehog 'off' state; HCMV Early Events; Intraflagellar transport; Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane; Gap junction assembly; Resolution of Sister Chromatid Cohesion; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Formation of tubulin folding intermediates by CCT/TriC; Post-chaperonin tubulin folding pathway; RHO GTPases activate IQGAPs; RHO GTPases Activate Formins; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Carboxyterminal post-translational modifications of tubulin; Assembly and cell surface presentation of NMDA receptors; Activation of AMPK downstream of NMDARs; Aggrephagy; EML4 and NUDC in mitotic spindle formation; Sealing of the nuclear envelope (NE) by ESCRT-III; RHOH GTPase cycle"	"Alzheimer's disease and miRNA effects; Pathogenic Escherichia coli infection; Allograft rejection; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"35"	"28"	"4120.7"	"4338.2"	"16709.6"	"3613.5"	"3037.5"	"2535.3"	"17858.5"	"1849.7"	"2536.1"	"1874.3"	"2006.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q71U36"	"Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1"	"55"	"22"	"79"	"2"	"451"	"50.1"	"5.06"	"13313.69"	"164.01"	"17"	"21"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00091, Pf03953"	"7846"	"ENSG00000167552"	"TUBA1A"	"A8K0B8; G3V1U9; hsa:7846; P04687; P05209; Q71U36"	"COPI-dependent Golgi-to-ER retrograde traffic; Separation of Sister Chromatids; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Kinesins; The role of GTSE1 in G2/M progression after G2 checkpoint; HCMV Early Events; Recycling pathway of L1; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Formation of tubulin folding intermediates by CCT/TriC; Prefoldin mediated transfer of substrate  to CCT/TriC; COPI-mediated anterograde transport; RHO GTPases activate IQGAPs; COPI-independent Golgi-to-ER retrograde traffic; Intraflagellar transport; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane; Gap junction assembly; Post-chaperonin tubulin folding pathway; Carboxyterminal post-translational modifications of tubulin; Assembly and cell surface presentation of NMDA receptors; Activation of AMPK downstream of NMDARs; Aggrephagy; Sealing of the nuclear envelope (NE) by ESCRT-III; Hedgehog 'off' state"	"Alzheimer's disease and miRNA effects; Pathogenic Escherichia coli infection; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"40"	"0"	"200.8"	"189.4"	"942.8"	"197.8"	"159.0"	"119.9"	"934.0"	"81.5"	"126.0"	"88.9"	"85.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04075"	"Fructose-bisphosphate aldolase A OS=Homo sapiens OX=9606 GN=ALDOA PE=1 SV=2"	"66"	"30"	"91"	"22"	"364"	"39.4"	"8.09"	"19535.21"	"163.62"	"26"	"25"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00274"	"226"	"ENSG00000149925"	"ALDOA"	"B4DXI7; hsa:226; P04075; Q6FH76; Q6FI10; Q96B15; Q9BWD9; Q9UCN2"	"Neutrophil degranulation; Glycolysis; Gluconeogenesis; Platelet degranulation"	"VEGFA-VEGFR2 signaling; Clear cell renal cell carcinoma pathways; Aerobic glycolysis; 16p11.2 proximal deletion syndrome; Glycolysis and gluconeogenesis; Sudden infant death syndrome (SIDS) susceptibility pathways"	"10"	"8"	"3354.7"	"5059.7"	"12049.4"	"4856.3"	"5162.4"	"5283.3"	"20549.9"	"5670.9"	"7574.3"	"5736.4"	"6610.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13010"	"X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3"	"48"	"33"	"88"	"33"	"732"	"82.7"	"5.81"	"18103.38"	"151.48"	"30"	"29"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf02735, Pf03730, Pf03731, Pf08785"	"7520"	"ENSG00000079246"	"XRCC5"	"A8K3X5; hsa:7520; P13010; Q0Z7V0; Q4VBQ5; Q53HH7; Q7M4N0; Q9UCQ0; Q9UCQ1"	"Neutrophil degranulation; Cytosolic sensors of pathogen-associated DNA ; Nonhomologous End-Joining (NHEJ); 2-LTR circle formation; IRF3-mediated induction of type I IFN"	"Non-homologous end joining; Male infertility; DNA repair pathways, full network; p53 transcriptional gene network; 10q11.21q11.23 copy number variation syndrome"	"10"	"0"	"3514.5"	"3874.4"	"12477.9"	"3925.2"	"3388.5"	"2856.3"	"14695.9"	"1956.7"	"2924.8"	"2394.7"	"2504.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04406"	"Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3"	"70"	"27"	"68"	"27"	"335"	"36.0"	"8.46"	"11222.69"	"150.68"	"19"	"26"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00044, Pf02800"	"2597"	"ENSG00000111640"	"GAPDH"	"E7EUT4; hsa:2597; P00354; P04406; Q53X65"	"Glycolysis; Gluconeogenesis"	"Cori cycle; Alzheimer's disease and miRNA effects; HIF1A and PPARG regulation of glycolysis; VEGFA-VEGFR2 signaling; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Aerobic glycolysis; 7q11.23 copy number variation syndrome; Glycolysis in senescence; Alzheimer's disease; Sildenafil treatment; Glycolysis and gluconeogenesis; Sudden infant death syndrome (SIDS) susceptibility pathways"	"15"	"0"	"3922.3"	"3605.9"	"12078.9"	"3699.9"	"2653.8"	"2013.6"	"13811.7"	"3042.6"	"4574.9"	"3901.2"	"4342.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11021"	"Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2"	"52"	"39"	"95"	"36"	"654"	"72.3"	"5.16"	"20119.23"	"147.74"	"35"	"33"	"protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;nucleus;other cell component"	"translation activity;other molecular function"	"Pf00012"	"3309"	"ENSG00000044574"	"HSPA5"	"B0QZ61; hsa:3309; P11021; Q2EF78; Q9NPF1; Q9UK02"	"Regulation of HSF1-mediated heat shock response; Platelet degranulation ; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; ATF6B (ATF6-beta) activates chaperones; IRE1alpha activates chaperones; PERK regulates gene expression; ATF6 (ATF6-alpha) activates chaperone genes"	"Parkin-ubiquitin proteasomal system pathway; Apoptosis-related network due to altered Notch3 in ovarian cancer; Photodynamic therapy-induced unfolded protein response; Prion disease pathway; Unfolded protein response; Orexin receptor pathway"	"14"	"0"	"4648.6"	"4918.2"	"15653.3"	"5623.2"	"4147.4"	"3198.6"	"20916.3"	"2952.1"	"4222.9"	"3568.4"	"3614.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P78527"	"DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3"	"12"	"39"	"82"	"39"	"4128"	"468.8"	"7.12"	"16353.09"	"142.39"	"39"	"38"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00454, Pf02259, Pf02260, Pf08163, Pf19704, Pf20502"	"5591"	"ENSG00000253729"	"PRKDC"	"hsa:5591; P78527; P78528; Q13327; Q13337; Q14175; Q59H99; Q7Z611; Q96SE6; Q9UME3"	"E3 ubiquitin ligases ubiquitinate target proteins; Cytosolic sensors of pathogen-associated DNA ; Nonhomologous End-Joining (NHEJ); IRF3-mediated induction of type I IFN"	"miRNA regulation of DNA damage response; Cell cycle; Retinoblastoma gene in cancer; Fas ligand pathway and stress induction of heat shock proteins; Pathways affected in adenoid cystic carcinoma; ATM signaling in development and disease ; Non-homologous end joining; Osteoblast differentiation and related diseases; DNA repair pathways, full network; DNA damage response"	"14"	"0"	"2498.2"	"2425.8"	"8420.1"	"2267.4"	"2041.6"	"1647.8"	"7412.1"	"904.9"	"1565.6"	"1318.3"	"1335.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7KZF4"	"Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1"	"38"	"29"	"67"	"29"	"910"	"101.9"	"7.17"	"12315.88"	"141.37"	"24"	"29"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00565, Pf00567"	"27044"	"ENSG00000197157"	"SND1"	"hsa:27044; Q13122; Q7KZF4; Q96AG0"	"Signaling by BRAF and RAF1 fusions"	"VEGFA-VEGFR2 signaling"	"2"	"0"	"3370.1"	"2934.2"	"7764.8"	"2489.4"	"2108.0"	"1732.2"	"9174.2"	"2049.5"	"2960.3"	"3088.1"	"4133.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19338"	"Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3"	"45"	"50"	"104"	"50"	"710"	"76.6"	"4.70"	"20131.19"	"139.68"	"46"	"33"	"developmental processes;other biological processes"	"plasma membrane;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"4691"	"ENSG00000115053"	"NCL"	"hsa:4691; P19338; Q53SK1; Q8NB06; Q9UCF0; Q9UDG1"	"Major pathway of rRNA processing in the nucleolus and cytosol"	"Pathogenic Escherichia coli infection; VEGFA-VEGFR2 signaling"	"3"	"0"	"7819.1"	"8691.6"	"22801.9"	"8532.6"	"7867.1"	"6908.0"	"38253.4"	"9161.0"	"13083.2"	"10335.7"	"8768.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13885"	"Tubulin beta-2A chain OS=Homo sapiens OX=9606 GN=TUBB2A PE=1 SV=1"	"53"	"21"	"78"	"1"	"445"	"49.9"	"4.89"	"16781.62"	"136.54"	"19"	"20"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00091, Pf03953"	"7280"	"ENSG00000137267"	"TUBB2A"	"hsa:7280; Q13885; Q6FGZ8; Q8IWR2"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; The role of GTSE1 in G2/M progression after G2 checkpoint; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Recruitment of NuMA to mitotic centrosomes; Aggrephagy; Translocation of SLC2A4 (GLUT4) to the plasma membrane; HCMV Early Events; Formation of tubulin folding intermediates by CCT/TriC; Prefoldin mediated transfer of substrate  to CCT/TriC; Intraflagellar transport; Recycling pathway of L1; COPI-dependent Golgi-to-ER retrograde traffic; Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane; Gap junction assembly; MHC class II antigen presentation; Post-chaperonin tubulin folding pathway; RHO GTPases activate IQGAPs; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Carboxyterminal post-translational modifications of tubulin; Assembly and cell surface presentation of NMDA receptors; Activation of AMPK downstream of NMDARs; Sealing of the nuclear envelope (NE) by ESCRT-III; Kinesins; Hedgehog 'off' state"	"Alzheimer's disease and miRNA effects; Pathogenic Escherichia coli infection; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"34"	"1"	"166.8"	"195.7"	"669.5"	"151.6"	"144.4"	"124.5"	"707.1"	"103.3"	"114.0"	"89.5"	"81.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P12956"	"X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2"	"49"	"31"	"77"	"31"	"609"	"69.8"	"6.64"	"14914.64"	"136.30"	"25"	"27"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02037, Pf02735, Pf03730, Pf03731"	"2547"	"ENSG00000196419"	"XRCC6"	"B1AHC8; hsa:2547; P12956; Q6FG89; Q9UCQ2; Q9UCQ3"	"Neutrophil degranulation; Cytosolic sensors of pathogen-associated DNA ; Nonhomologous End-Joining (NHEJ); 2-LTR circle formation; IRF3-mediated induction of type I IFN"	"Non-homologous end joining; DNA repair pathways, full network; Primary ovarian insufficiency; 10q11.21q11.23 copy number variation syndrome"	"9"	"0"	"3622.5"	"4044.0"	"12598.4"	"3995.4"	"3385.9"	"2907.1"	"14649.3"	"2114.2"	"3123.9"	"2628.8"	"2754.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06733"	"Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2"	"57"	"26"	"71"	"26"	"434"	"47.1"	"7.39"	"13244.51"	"135.89"	"21"	"24"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00113, Pf03952"	"2023"	"ENSG00000074800"	"ENO1"	"B2RD59; hsa:2023; P06733; P22712; Q16704; Q4TUS4; Q53FT9; Q53HR3; Q658M5; Q6GMP2; Q71V37; Q7Z3V6; Q8WU71; Q96GV1; Q9BT62; Q9UCH6; Q9UM55"	"Glycolysis; Gluconeogenesis; Manipulation of host energy metabolism"	"Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Aerobic glycolysis; IL-18 signaling pathway; Glycolysis and gluconeogenesis"	"8"	"0"	"3036.8"	"3262.7"	"15366.2"	"3724.7"	"2816.4"	"1796.1"	"29577.9"	"3064.9"	"3357.3"	"2487.7"	"2174.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P38646"	"Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2"	"48"	"32"	"68"	"31"	"679"	"73.6"	"6.16"	"11174.22"	"134.75"	"24"	"30"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00012"	"3313"	"ENSG00000113013"	"HSPA9"	"B2RCM1; hsa:3313; P30036; P31932; P38646; Q1HB43; Q53H23; Q6GU03; Q9BWB7; Q9UC56"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Mitochondrial protein import; Regulation of HSF1-mediated heat shock response; Cristae formation"	"Parkin-ubiquitin proteasomal system pathway; Iron-sulfur cluster biogenesis"	"6"	"0"	"3246.9"	"4189.2"	"13422.3"	"4427.3"	"4035.5"	"3548.6"	"17587.7"	"2660.8"	"4068.7"	"3108.9"	"3280.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09874"	"Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4"	"42"	"40"	"87"	"40"	"1014"	"113.0"	"8.88"	"17827.39"	"134.31"	"38"	"35"	"cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00533, Pf00644, Pf00645, Pf02877, Pf05406, Pf08063"	"142"	"ENSG00000143799"	"PARP1"	"B1ANJ4; hsa:142; P09874; Q8IUZ9"	"SUMOylation of DNA damage response and repair proteins; Downregulation of SMAD2/3:SMAD4 transcriptional activity; HDR through MMEJ (alt-NHEJ); Formation of Incision Complex in GG-NER; DNA Damage Recognition in GG-NER; vRNA Synthesis; POLB-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER"	"Corticotropin-releasing hormone signaling pathway; Nanoparticle triggered regulated necrosis; Fas ligand pathway and stress induction of heat shock proteins; NAD metabolism, sirtuins and aging; NAD+ metabolism; NAD+ biosynthetic pathways; Breast cancer pathway; Acute viral myocarditis; Joubert syndrome; Male infertility; Base excision repair; IL-18 signaling pathway; DNA repair pathways, full network; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Progeria-associated lipodystrophy; Primary ovarian insufficiency; 10q11.21q11.23 copy number variation syndrome; A network map of Macrophage-stimulating protein (MSP) signaling"	"26"	"0"	"5335.4"	"5561.9"	"18275.1"	"5099.1"	"4141.6"	"3593.1"	"17260.1"	"3221.7"	"4318.5"	"4445.0"	"5988.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22626"	"Heterogeneous nuclear ribonucleoproteins A2/B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2"	"57"	"18"	"57"	"16"	"353"	"37.4"	"8.95"	"9590.30"	"128.30"	"14"	"15"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"3181"	"ENSG00000122566"	"HNRNPA2B1"	"A0A024RA27; A0A024RA61; A8K064; hsa:3181; P22626; P22627; Q9UC98; Q9UDJ2"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"mRNA processing"	"4"	"2"	"3573.3"	"3564.3"	"8849.9"	"2928.5"	"2692.3"	"2398.3"	"9920.4"	"2342.7"	"3264.2"	"2428.6"	"2901.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P53396"	"ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3"	"36"	"38"	"84"	"38"	"1101"	"120.8"	"7.33"	"16948.62"	"125.60"	"37"	"31"	"other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00285, Pf00549, Pf02629, Pf16114"	"47"	"ENSG00000131473"	"ACLY"	"B4DIM0; B4E3P0; hsa:47; P53396; Q13037; Q9BRL0"	"Neutrophil degranulation; ChREBP activates metabolic gene expression; Fatty acyl-CoA biosynthesis"	"Sterol regulatory element-binding proteins (SREBP) signaling; TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Fatty acid biosynthesis; Amino acid metabolism; Lipid metabolism pathway; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer"	"10"	"0"	"5142.1"	"5610.0"	"14807.8"	"5083.8"	"4583.2"	"3889.4"	"18833.6"	"3842.4"	"5054.9"	"4286.9"	"4336.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14625"	"Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1"	"47"	"35"	"66"	"34"	"803"	"92.4"	"4.84"	"11550.36"	"125.11"	"29"	"30"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00183, Pf02518"	"7184"	"ENSG00000166598"	"HSP90B1"	"hsa:7184; P14625; Q96A97"	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Interleukin-4 and Interleukin-13 signaling; Trafficking and processing of endosomal TLR; Scavenging by Class A Receptors; ATF6 (ATF6-alpha) activates chaperone genes"	"Photodynamic therapy-induced unfolded protein response; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Prion disease pathway; PI3K-Akt signaling pathway; Sudden infant death syndrome (SIDS) susceptibility pathways"	"11"	"0"	"3318.6"	"4059.2"	"14877.7"	"3427.0"	"2928.2"	"2089.8"	"16835.9"	"1658.6"	"4216.9"	"3482.4"	"3354.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60709"	"Actin, cytoplasmic 1 OS=Homo sapiens OX=9606 GN=ACTB PE=1 SV=1"	"53"	"20"	"76"	"5"	"375"	"41.7"	"5.48"	"15150.19"	"124.79"	"15"	"18"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00022"	"60"	"ENSG00000075624"	"ACTB"	"hsa:60; P02570; P60709; P70514; P99021; Q11211; Q64316; Q75MN2; Q96B34; Q96HG5"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; UCH proteinases; Clathrin-mediated endocytosis; DNA Damage Recognition in GG-NER; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; VEGFA-VEGFR2 Pathway; RHOF GTPase cycle; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; Recycling pathway of L1; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; RHO GTPases Activate WASPs and WAVEs; RHO GTPases activate IQGAPs; RHO GTPases Activate Formins; B-WICH complex positively regulates rRNA expression; Signaling by BRAF and RAF1 fusions; EPHB-mediated forward signaling; Factors involved in megakaryocyte development and platelet production; EPH-ephrin mediated repulsion of cells; HATs acetylate histones; Interaction between L1 and Ankyrins; Prefoldin mediated transfer of substrate  to CCT/TriC; Signaling by RAF1 mutants; Adherens junctions interactions; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; Formation of annular gap junctions; Folding of actin by CCT/TriC; Cell-extracellular matrix interactions"	"Arrhythmogenic right ventricular cardiomyopathy; Pathogenic Escherichia coli infection; Common pathways underlying drug addiction; Myometrial relaxation and contraction pathways; Focal adhesion; Fas ligand pathway and stress induction of heat shock proteins; Ebola virus infection in host; Acute viral myocarditis; Thermogenesis; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Overlap between signal transduction pathways contributing to LMNA laminopathies; Pleural mesothelioma; Regulation of actin cytoskeleton; Network map of SARS-CoV-2 signaling pathway"	"47"	"19"	"2680.2"	"3012.4"	"15603.5"	"2546.4"	"2041.3"	"1426.1"	"20222.9"	"1658.3"	"1569.1"	"1342.5"	"1189.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25705"	"ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1"	"51"	"31"	"74"	"31"	"553"	"59.7"	"9.13"	"15237.73"	"122.54"	"28"	"25"	"other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;transporter activity;other molecular function"	"Pf00006, Pf00306, Pf02874"	"498"	"ENSG00000152234"	"ATP5F1A"	"A8K092; B4DY56; hsa:498; K7ENP3; P25705; Q53XX6; Q8IXV2; Q96FB4; Q96HW2; Q96IR6; Q9BTV8"	"Mitochondrial protein import; Cristae formation; Formation of ATP by chemiosmotic coupling"	"Electron transport chain: OXPHOS system in mitochondria; 7q11.23 copy number variation syndrome; Oxidative phosphorylation"	"6"	"0"	"4464.0"	"4591.0"	"18056.0"	"4023.6"	"3267.3"	"2480.7"	"17663.3"	"2194.4"	"3195.0"	"2641.5"	"2850.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P78371"	"T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4"	"64"	"27"	"60"	"27"	"535"	"57.5"	"6.46"	"11824.02"	"122.35"	"21"	"25"	"cell organization and biogenesis;transport;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00118"	"10576"	"ENSG00000166226"	"CCT2"	"A8K402; B5BTY7; B7Z243; B7Z7K4; B7ZAT2; hsa:10576; P78371; Q14D36; Q6IAT3"	"Neutrophil degranulation; Formation of tubulin folding intermediates by CCT/TriC; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; RHOBTB2 GTPase cycle; Folding of actin by CCT/TriC; BBSome-mediated cargo-targeting to cilium; RHOBTB1 GTPase cycle"	"16p11.2 proximal deletion syndrome"	"10"	"0"	"2513.3"	"2861.8"	"8330.0"	"2424.3"	"2303.5"	"1802.7"	"7910.2"	"1139.1"	"1606.6"	"1458.3"	"1351.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50991"	"T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4"	"58"	"24"	"66"	"24"	"539"	"57.9"	"7.83"	"13427.51"	"120.69"	"20"	"23"	"transport;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00118"	"10575"	"ENSG00000115484"	"CCT4"	"B2R6I3; B7Z8B1; F5H5W3; hsa:10575; O14870; P50991; Q53QP9; Q96C51"	"Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; Folding of actin by CCT/TriC"	"16p11.2 proximal deletion syndrome"	"7"	"0"	"4108.6"	"4656.9"	"13571.8"	"4119.6"	"3572.6"	"2832.0"	"13171.6"	"1878.4"	"2785.4"	"2416.1"	"2406.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P54577"	"Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4"	"60"	"34"	"76"	"34"	"528"	"59.1"	"7.05"	"14487.84"	"120.58"	"33"	"29"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00579, Pf01588"	"8565"	"ENSG00000134684"	"YARS1"	"B3KWK4; D3DPQ4; hsa:8565; O43276; P54577; Q53EN1"	"Cytosolic tRNA aminoacylation"	"Nephrotic syndrome"	"2"	"0"	"2565.2"	"3051.5"	"11191.8"	"2706.5"	"2195.0"	"1898.8"	"11018.4"	"2793.3"	"7295.4"	"11784.2"	"14345.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22234"	"Multifunctional protein ADE2 OS=Homo sapiens OX=9606 GN=PAICS PE=1 SV=3"	"42"	"21"	"65"	"21"	"425"	"47.0"	"7.23"	"11905.30"	"120.25"	"18"	"19"	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00731, Pf01259"	"10606"	"ENSG00000128050"	"PAICS"	"E9PDH9; hsa:10606; P22234; Q68CQ5"	"Purine ribonucleoside monophosphate biosynthesis"	"Metabolic reprogramming in colon cancer"	"2"	"0"	"2546.5"	"2604.1"	"5944.4"	"2310.5"	"2338.7"	"1903.8"	"7002.3"	"1757.1"	"2656.9"	"3370.2"	"6115.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P00558"	"Phosphoglycerate kinase 1 OS=Homo sapiens OX=9606 GN=PGK1 PE=1 SV=3"	"69"	"27"	"68"	"27"	"417"	"44.6"	"8.10"	"12484.56"	"120.11"	"24"	"23"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;other membranes;cytosol"	"kinase activity;other molecular function"	"Pf00162"	"5230"	"ENSG00000102144"	"PGK1"	"A8K4W6; B7Z7A9; hsa:5230; P00558; Q5J7W1; Q6IBT6; Q8NI87"	"Gluconeogenesis; Glycolysis; Manipulation of host energy metabolism"	"Cori cycle; Photodynamic therapy-induced HIF-1 survival signaling; VEGFA-VEGFR2 signaling; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Aerobic glycolysis; Glycolysis in senescence; Glycolysis and gluconeogenesis"	"11"	"0"	"2240.5"	"2637.5"	"11186.0"	"2620.9"	"2219.6"	"1697.3"	"18660.5"	"2500.4"	"4066.3"	"5405.9"	"14512.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P40926"	"Malate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=MDH2 PE=1 SV=3"	"59"	"19"	"64"	"19"	"338"	"35.5"	"8.68"	"10087.57"	"119.15"	"16"	"18"	"other metabolic processes"	"other membranes;mitochondrion;other cell component"	"other molecular function"	"Pf00056, Pf02866"	"4191"	"ENSG00000146701"	"MDH2"	"A8K414; B2RE78; B4DE44; E9PDB2; hsa:4191; O43682; P40926"	"Gluconeogenesis; Citric acid cycle (TCA cycle)"	"Amino acid metabolism; Metabolic reprogramming in colon cancer; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Glycolysis and gluconeogenesis; TCA cycle (aka Krebs or citric acid cycle)"	"7"	"0"	"2178.8"	"2399.4"	"5826.5"	"2666.4"	"2067.4"	"1585.7"	"10183.4"	"3874.2"	"5198.4"	"4524.6"	"5717.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14152"	"Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1"	"26"	"35"	"71"	"35"	"1382"	"166.5"	"6.79"	"13400.08"	"118.36"	"32"	"31"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;translational apparatus;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf01399"	"8661"	"ENSG00000107581"	"EIF3A"	"B1AMV5; B4DYS1; F5H335; hsa:8661; O00653; Q14152; Q15778"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"8"	"0"	"3858.2"	"3987.5"	"11431.8"	"3676.6"	"3458.6"	"3054.5"	"11920.2"	"1781.9"	"2805.8"	"2402.0"	"2435.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60891"	"Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2"	"59"	"20"	"68"	"8"	"318"	"34.8"	"6.98"	"13342.36"	"116.90"	"16"	"18"	"other metabolic processes;developmental processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf13793, Pf14572"	"5631"	"ENSG00000147224"	"PRPS1"	"B1ALA8; B2R6T7; B4DNL6; D3DUX6; hsa:5631; P09329; P60891"	"5-Phosphoribose 1-diphosphate biosynthesis"	""	"1"	"16"	"1788.9"	"3222.9"	"6593.2"	"2807.6"	"2768.2"	"2537.3"	"6300.0"	"2294.1"	"4088.0"	"5199.3"	"8249.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q08211"	"ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4"	"29"	"31"	"68"	"31"	"1270"	"140.9"	"6.84"	"13554.90"	"114.71"	"26"	"27"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;cytoskeleton;translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00035, Pf00270, Pf00271, Pf04408, Pf07717"	"1660"	"ENSG00000135829"	"DHX9"	"B2RNV4; hsa:1660; Q05CI5; Q08211; Q12803; Q32Q22; Q5VY62; Q6PD69; Q99556"	"mRNA Splicing - Major Pathway; RIP-mediated NFkB activation via ZBP1; DEx/H-box helicases activate type I IFN and inflammatory cytokines production"	"MECP2 and associated Rett syndrome; mRNA processing"	"5"	"0"	"1892.9"	"2056.7"	"5715.6"	"1951.0"	"1964.8"	"1627.2"	"7374.5"	"1535.2"	"3061.8"	"3563.2"	"4203.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55072"	"Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4"	"43"	"32"	"61"	"32"	"806"	"89.3"	"5.26"	"12035.76"	"113.42"	"26"	"28"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"non-structural extracellular;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00004, Pf02359, Pf02933, Pf09336, Pf17862"	"7415"	"ENSG00000165280"	"VCP"	"B2R5T8; hsa:7415; P55072; Q0V924; Q2TAI5; Q969G7; Q9UCD5"	"Neutrophil degranulation; Aggrephagy; HSF1 activation; ABC-family proteins mediated transport; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Defective CFTR causes cystic fibrosis; Neddylation; KEAP1-NFE2L2 pathway; RHOH GTPase cycle; E3 ubiquitin ligases ubiquitinate target proteins; Attachment and Entry; Attachment and Entry; Ovarian tumor domain proteases; Josephin domain DUBs; Protein methylation; Translesion Synthesis by POLH; N-glycan trimming in the ER and Calnexin/Calreticulin cycle"	"Alstrom syndrome; Clock-controlled autophagy in bone metabolism"	"20"	"0"	"2760.7"	"3406.3"	"11675.3"	"3520.9"	"3087.2"	"2804.6"	"16513.6"	"3438.7"	"3975.5"	"3274.1"	"3307.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61978"	"Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1"	"44"	"22"	"60"	"22"	"463"	"50.9"	"5.54"	"12054.02"	"112.63"	"19"	"20"	"RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf08067"	"3190"	"ENSG00000165119"	"HNRNPK"	"hsa:3190; P61978; Q07244; Q15671; Q59F98; Q5T6W4; Q60577; Q6IBN1; Q922Y7; Q96J62"	"mRNA Splicing - Major Pathway; HCMV Late Events; SUMOylation of RNA binding proteins; Processing of Capped Intron-Containing Pre-mRNA"	"mRNA processing; lncRNA in canonical Wnt signaling and colorectal cancer"	"6"	"0"	"2468.3"	"3776.5"	"11200.5"	"3701.2"	"3321.0"	"3162.5"	"12266.4"	"2260.8"	"2911.3"	"2236.1"	"2227.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50990"	"T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4"	"56"	"30"	"61"	"30"	"548"	"59.6"	"5.60"	"11560.86"	"110.81"	"24"	"26"	"cell organization and biogenesis;transport;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00118"	"10694"	"ENSG00000156261"	"CCT8"	"A6NN54; B4DEM7; B4DQH4; hsa:10694; P50990; Q4VBP8"	"Neutrophil degranulation; Association of TriC/CCT with target proteins during biosynthesis; Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; Folding of actin by CCT/TriC"	"16p11.2 proximal deletion syndrome"	"8"	"0"	"3973.4"	"4531.7"	"13010.9"	"3796.9"	"3343.1"	"2762.9"	"11516.4"	"1701.0"	"2544.0"	"2376.4"	"2340.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62258"	"14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1"	"54"	"17"	"72"	"15"	"255"	"29.2"	"4.74"	"14594.79"	"106.55"	"16"	"15"	"stress response;transport;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00244"	"7531"	"ENSG00000108953; ENSG00000274474"	"YWHAE"	"B3KY71; D3DTH5; hsa:7531; P29360; P42655; P62258; Q4VJB6; Q53XZ5; Q63631; Q7M4R4"	"RAB GEFs exchange GTP for GDP on RABs; Translocation of SLC2A4 (GLUT4) to the plasma membrane; TP53 Regulates Metabolic Genes; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Activation of BAD and translocation to mitochondria ; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models; Recruitment of NuMA to mitotic centrosomes; Regulation of HSF1-mediated heat shock response; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Signaling by Hippo; HSF1 activation; NADE modulates death signalling"	"Cell cycle; Myometrial relaxation and contraction pathways; VEGFA-VEGFR2 signaling; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"25"	"4"	"2352.8"	"3518.4"	"12076.3"	"2872.8"	"2808.5"	"2439.9"	"15747.5"	"2395.0"	"3066.4"	"2372.1"	"2729.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11586"	"C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=3"	"37"	"33"	"68"	"32"	"935"	"101.5"	"7.30"	"13244.75"	"104.83"	"28"	"26"	""	""	""	""	""	""	""	""	""	""	"0"	"1"	"2551.9"	"2356.5"	"8364.7"	"2297.7"	"2035.9"	"1578.3"	"12329.1"	"2297.0"	"3452.7"	"3039.7"	"3262.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P00367"	"Glutamate dehydrogenase 1, mitochondrial OS=Homo sapiens OX=9606 GN=GLUD1 PE=1 SV=2"	"44"	"26"	"61"	"26"	"558"	"61.4"	"7.80"	"11178.46"	"103.85"	"24"	"24"	"other metabolic processes;other biological processes"	"mitochondrion;ER/Golgi;other cell component"	"other molecular function"	"Pf00208, Pf02812"	"2746"	"ENSG00000148672"	"GLUD1"	"B3KV55; B4DGN5; hsa:2746; P00367; Q5TBU3"	"Transcriptional activation of mitochondrial biogenesis; Glutamate and glutamine metabolism"	"VEGFA-VEGFR2 signaling; Amino acid metabolism; Metabolic reprogramming in colon cancer; 22q11.2 copy number variation syndrome; Amino acid metabolism pathway excerpt: histidine catabolism extension"	"7"	"0"	"2308.7"	"2698.9"	"5902.4"	"2754.1"	"2617.8"	"2442.9"	"11834.8"	"3943.9"	"5581.6"	"4397.0"	"4081.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04259"	"Keratin, type II cytoskeletal 6B OS=Homo sapiens OX=9606 GN=KRT6B PE=1 SV=5"	"30"	"21"	"59"	"1"	"564"	"60.0"	"8.00"	"11312.47"	"102.46"	"20"	"21"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton"	"bone, tooth or skin structural activity;cytoskeletal activity"	"Pf00038, Pf16208"	"3854"	"ENSG00000185479"	"KRT6B"	"hsa:3854; P04259; P48669"	"Formation of the cornified envelope"	""	"2"	"6"	"9983.0"	"1198.2"	"2265.7"	"1420.0"	"275.6"	"268.7"	"819.3"	"245.5"	"222.5"	"207.9"	"228.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P17987"	"T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1"	"49"	"23"	"53"	"23"	"556"	"60.3"	"6.11"	"9199.41"	"101.90"	"17"	"22"	"cell organization and biogenesis;transport;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf00118"	"6950"	"ENSG00000120438"	"TCP1"	"E1P5B2; hsa:6950; P17987; Q15556; Q5TCM3"	"Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; Folding of actin by CCT/TriC"	"16p11.2 proximal deletion syndrome"	"8"	"0"	"2657.4"	"2983.7"	"8593.4"	"2671.3"	"2326.2"	"1897.0"	"8491.1"	"1250.1"	"1869.4"	"1594.6"	"1569.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P68104"	"Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1"	"44"	"17"	"50"	"17"	"462"	"50.1"	"9.01"	"7358.23"	"100.65"	"13"	"12"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;translational apparatus;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03143, Pf03144"	"1915"	"ENSG00000156508"	"EEF1A1"	"hsa:1915; P04719; P04720; P68104; Q6IQ15"	"Chaperone Mediated Autophagy; Peptide chain elongation; SARS-CoV-1 modulates host translation machinery; Neutrophil degranulation; Protein methylation; HSF1 activation"	"Translation factors; Fragile X syndrome; 2q37 copy number variation syndrome"	"10"	"0"	"4057.7"	"4457.9"	"12032.8"	"3575.1"	"3008.1"	"2409.8"	"13570.0"	"2982.9"	"3576.3"	"3196.9"	"3659.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5JRX3"	"Presequence protease, mitochondrial OS=Homo sapiens OX=9606 GN=PITRM1 PE=1 SV=3"	"29"	"23"	"37"	"23"	"1037"	"117.3"	"6.92"	"4261.00"	"100.27"	"9"	"22"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport"	"mitochondrion"	"enzyme regulator activity;other molecular function"	"Pf00675, Pf05193, Pf08367"	"10531"	"ENSG00000107959"	"PITRM1"	"B3KMJ6; B4E0J8; C9JSL2; E7ES23; hsa:10531; O95204; Q2M2G6; Q4VBR1; Q5JRW7; Q5JRX3; Q7L5Z7; Q9BSI6; Q9BVJ5; Q9UPP8"	"Mitochondrial protein import"	""	"1"	"0"	"840.4"	"851.3"	"2782.9"	"898.6"	"834.8"	"688.3"	"3292.6"	"579.6"	"1551.8"	"4440.0"	"13021.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P2J5"	"Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2"	"27"	"29"	"56"	"29"	"1176"	"134.4"	"7.30"	"9194.72"	"99.72"	"22"	"27"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00133, Pf08264"	"51520"	"ENSG00000133706"	"LARS1"	"A2RRR4; A7E266; B4DJ10; hsa:51520; Q2TU79; Q9NSE1; Q9P2J5"	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	""	"2"	"0"	"2626.4"	"3671.6"	"9294.1"	"3395.9"	"3233.2"	"2916.7"	"8293.4"	"1231.6"	"1925.0"	"1573.0"	"1794.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q00610"	"Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5"	"21"	"26"	"52"	"26"	"1675"	"191.5"	"5.69"	"9949.99"	"99.46"	"22"	"25"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00637, Pf01394, Pf09268, Pf13838"	"1213"	"ENSG00000141367"	"CLTC"	"D3DU00; hsa:1213; Q00610; Q6N0A0; Q86TF2"	"ALK mutants bind TKIs; Nuclear events stimulated by ALK signaling in cancer; Lysosome Vesicle Biogenesis; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; Formation of annular gap junctions; Recycling pathway of L1; MHC class II antigen presentation; RHOV GTPase cycle; RHOU GTPase cycle; LDL clearance; Retrograde neurotrophin signalling; VLDLR internalisation and degradation; Entry of Influenza Virion into Host Cell via Endocytosis"	"Synaptic vesicle pathway; VEGFA-VEGFR2 signaling; Ebola virus infection in host; Fragile X syndrome; 7q11.23 copy number variation syndrome; Complement and coagulation cascades"	"25"	"0"	"1729.4"	"1991.3"	"6106.4"	"1898.3"	"1807.8"	"1677.4"	"7516.1"	"1101.7"	"1673.8"	"1253.9"	"1328.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13647"	"Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3"	"33"	"25"	"61"	"13"	"590"	"62.3"	"7.74"	"10850.42"	"98.54"	"22"	"24"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;other cell component"	"bone, tooth or skin structural activity;cytoskeletal activity;other molecular function"	"Pf00038, Pf16208"	"3852"	"ENSG00000186081"	"KRT5"	"hsa:3852; P13647; Q6PI71; Q6UBJ0; Q8TA91"	"Formation of the cornified envelope; Type I hemidesmosome assembly"	""	"3"	"3"	"10701.6"	"4625.7"	"3071.7"	"1446.0"	"603.3"	"833.7"	"1872.9"	"752.1"	"350.7"	"288.9"	"471.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99832"	"T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2"	"43"	"24"	"49"	"24"	"543"	"59.3"	"7.65"	"7801.14"	"96.14"	"18"	"23"	"transport;other biological processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00118"	"10574"	"ENSG00000135624"	"CCT7"	"A8K7E6; A8MWI8; B7WNW9; B7Z4T9; B7Z4Z7; hsa:10574; O14871; Q6FI26; Q99832"	"Formation of tubulin folding intermediates by CCT/TriC; RHOBTB1 GTPase cycle; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; RHOBTB2 GTPase cycle; Folding of actin by CCT/TriC"	"VEGFA-VEGFR2 signaling; 16p11.2 proximal deletion syndrome"	"9"	"0"	"2934.5"	"3500.1"	"10398.9"	"3187.1"	"2674.2"	"2176.0"	"10339.0"	"1367.8"	"2019.9"	"1760.9"	"1800.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75369"	"Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2"	"13"	"27"	"49"	"24"	"2602"	"278.0"	"5.73"	"8765.44"	"95.90"	"23"	"26"	"cell organization and biogenesis;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00630"	"2317"	"ENSG00000136068"	"FLNB"	"B2ZZ83; B2ZZ84; B2ZZ85; C9JKE6; C9JMC4; hsa:2317; O75369; Q13706; Q59EC2; Q60FE7; Q6MZJ1; Q8WXS9; Q8WXT0; Q8WXT1; Q8WXT2; Q8WXT3; Q9NRB5; Q9NT26; Q9UEV9"	"ISG15 antiviral mechanism"	"Focal adhesion; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Ebola virus infection in host"	"5"	"2"	"1599.6"	"1848.8"	"5998.9"	"1635.5"	"1561.5"	"1150.5"	"7099.9"	"909.8"	"1429.4"	"1084.4"	"1104.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07814"	"Bifunctional glutamate/proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5"	"23"	"30"	"55"	"29"	"1512"	"170.5"	"7.33"	"9623.06"	"95.41"	"23"	"25"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00043, Pf00458, Pf00587, Pf00749, Pf03129, Pf03950, Pf09180"	"2058"	"ENSG00000136628"	"EPRS1"	"A0AVA9; B9EGH3; hsa:2058; P07814; Q05BP6; Q05DF8; Q5DSM1; Q5H9S5; Q6PD57; Q86X73"	"tRNA modification in the nucleus and cytosol; Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"Parkinson's disease pathway; VEGFA-VEGFR2 signaling; Amino acid metabolism"	"6"	"1"	"3378.3"	"3676.2"	"14534.0"	"2973.3"	"2399.0"	"1844.8"	"13902.5"	"1436.9"	"2163.2"	"1769.7"	"1996.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P27816"	"Microtubule-associated protein 4 OS=Homo sapiens OX=9606 GN=MAP4 PE=1 SV=3"	"33"	"31"	"61"	"31"	"1152"	"120.9"	"5.43"	"12447.11"	"95.18"	"29"	"27"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00418"	"4134"	"ENSG00000047849"	"MAP4"	"hsa:4134; P27816; Q13082; Q59FT2; Q68D74; Q6ZUW9; Q86V26; Q96A76; Q96NS9"	""	"Splicing factor NOVA regulated synaptic proteins; 2q37 copy number variation syndrome"	"2"	"0"	"2625.2"	"2683.9"	"7959.7"	"2862.2"	"2650.8"	"2320.6"	"11622.3"	"2251.7"	"3947.6"	"3006.8"	"2982.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62701"	"40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2"	"55"	"23"	"60"	"23"	"263"	"29.6"	"10.15"	"10843.28"	"94.34"	"23"	"19"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00467, Pf00900, Pf01479, Pf08071, Pf16121"	"6191"	"ENSG00000198034"	"RPS4X"	"hsa:6191; P12631; P12750; P27576; P55831; P62701; Q14727; Q6IPY4"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"4977.4"	"5220.7"	"15505.2"	"4618.6"	"4304.5"	"3887.0"	"15446.8"	"1933.5"	"2928.7"	"2148.9"	"2090.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08779"	"Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4"	"41"	"21"	"60"	"9"	"473"	"51.2"	"5.05"	"11521.57"	"94.30"	"19"	"21"	"cell organization and biogenesis;stress response;other biological processes"	"plasma membrane;cytosol;cytoskeleton"	"cytoskeletal activity"	"Pf00038"	"3868"	"ENSG00000186832"	"KRT16"	"A8K488; hsa:3868; P08779; P30654; Q16402; Q9UBG8"	"Formation of the cornified envelope"	"Vitamin D receptor pathway"	"3"	"6"	"16607.9"	"2588.4"	"3623.6"	"2470.7"	"542.5"	"491.5"	"2027.0"	"559.4"	"530.1"	"455.9"	"502.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q00839"	"Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6"	"35"	"26"	"50"	"25"	"825"	"90.5"	"6.00"	"8801.89"	"94.22"	"20"	"21"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00622, Pf02037, Pf13671"	"3192"	"ENSG00000153187"	"HNRNPU"	"hsa:3192; O75507; Q00839; Q8N174; Q96HY9; Q9BQ09"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"mRNA processing; lncRNA in canonical Wnt signaling and colorectal cancer"	"4"	"1"	"4358.2"	"4664.5"	"16459.3"	"4478.3"	"4031.3"	"3323.1"	"17763.3"	"1595.0"	"2655.6"	"1942.5"	"1908.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23284"	"Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2"	"59"	"15"	"46"	"15"	"216"	"23.7"	"9.41"	"8200.93"	"93.69"	"13"	"14"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00160"	"5479"	"ENSG00000166794"	"PPIB"	"A8K534; hsa:5479; P23284; Q6IBH5; Q9BVK5"	"Collagen biosynthesis and modifying enzymes; SARS-CoV-1 activates/modulates innate immune responses"	"Prolactin signaling pathway; Type I collagen synthesis in the context of osteogenesis imperfecta"	"4"	"0"	"656.7"	"705.8"	"2175.6"	"760.9"	"689.9"	"554.4"	"4095.0"	"2186.0"	"7234.8"	"11239.2"	"13258.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14697"	"Neutral alpha-glucosidase AB OS=Homo sapiens OX=9606 GN=GANAB PE=1 SV=3"	"30"	"22"	"49"	"22"	"944"	"106.8"	"6.14"	"6632.16"	"93.40"	"15"	"21"	"protein metabolism;other metabolic processes"	"ER/Golgi;other cell component"	"other molecular function"	"Pf01055, Pf13802"	"23193"	"ENSG00000089597"	"GANAB"	"A6NC20; hsa:23193; Q14697; Q8WTS9; Q9P0X0"	"Maturation of spike protein; Calnexin/calreticulin cycle; Maturation of spike protein"	"N-glycan biosynthesis"	"5"	"0"	"1216.5"	"1790.4"	"6049.7"	"1746.3"	"1797.6"	"1653.0"	"7195.9"	"1036.8"	"1445.5"	"1182.2"	"1146.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23396"	"40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2"	"66"	"18"	"56"	"18"	"243"	"26.7"	"9.66"	"9840.29"	"93.02"	"17"	"18"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;translational apparatus;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00189, Pf07650"	"6188"	"ENSG00000149273"	"RPS3"	"B2R7N5; hsa:6188; J3KN86; P23396; Q498B5; Q8NI95"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"2791.9"	"3163.3"	"9712.8"	"2640.1"	"2410.4"	"2161.9"	"8772.5"	"973.6"	"1539.2"	"1218.2"	"1231.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P02538"	"Keratin, type II cytoskeletal 6A OS=Homo sapiens OX=9606 GN=KRT6A PE=1 SV=3"	"31"	"21"	"54"	"2"	"564"	"60.0"	"8.00"	"10326.64"	"91.81"	"20"	"21"	"cell organization and biogenesis;stress response;other biological processes"	"cytosol;cytoskeleton"	"bone, tooth or skin structural activity;cytoskeletal activity"	"Pf00038, Pf16208"	"3853"	"ENSG00000205420"	"KRT6A"	"A4QPC1; hsa:3853; P02538; P48667; Q08AR4; Q6NT67; Q96CL4"	"Formation of the cornified envelope"	"Ectoderm differentiation; Ectoderm differentiation; Pancreatic cancer subtypes"	"5"	"0"	"2820.9"	"514.2"	"722.2"	"594.9"	"94.4"	"81.7"	"276.0"	"75.0"	"60.4"	"50.4"	"61.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92945"	"Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4"	"40"	"27"	"54"	"21"	"711"	"73.1"	"7.30"	"11100.99"	"91.57"	"25"	"22"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf09005"	"8570"	"ENSG00000088247"	"KHSRP"	"hsa:8570; O00301; Q59EZ9; Q5U4P6; Q92945; Q9UNT5; Q9UQH5"	"ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA"	"Pre-implantation embryo"	"3"	"6"	"2391.0"	"2739.6"	"11579.3"	"2629.0"	"2293.3"	"1861.3"	"15078.6"	"1780.9"	"2420.9"	"1931.4"	"2049.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q06830"	"Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1"	"49"	"14"	"50"	"11"	"199"	"22.1"	"8.13"	"9160.84"	"91.22"	"13"	"13"	"cell cycle OR cell proliferation;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00578, Pf10417"	"5052"	"ENSG00000117450"	"PRDX1"	"B5BU26; D3DPZ8; hsa:5052; P35703; Q06830; Q2V576; Q5T154; Q5T155"	"Detoxification of Reactive Oxygen Species; TP53 Regulates Metabolic Genes; NFE2L2 regulating anti-oxidant/detoxification enzymes; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"	"Androgen receptor signaling pathway; Selenium micronutrient network; Nuclear receptors meta-pathway; NRF2 pathway"	"8"	"5"	"1871.8"	"2325.5"	"6612.6"	"2250.6"	"1920.8"	"1856.2"	"8996.9"	"1702.4"	"2624.4"	"1847.1"	"1748.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P68032"	"Actin, alpha cardiac muscle 1 OS=Homo sapiens OX=9606 GN=ACTC1 PE=1 SV=1"	"34"	"16"	"66"	"1"	"377"	"42.0"	"5.39"	"14060.38"	"90.69"	"14"	"14"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00022"	"70"	"ENSG00000159251"	"ACTC1"	"hsa:70; P04270; P68032"	"RHOA GTPase cycle; Striated Muscle Contraction; RHOB GTPase cycle"	"Cardiac progenitor differentiation; Myometrial relaxation and contraction pathways; Striated muscle contraction pathway; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; 22q11.2 copy number variation syndrome; Pleural mesothelioma"	"9"	"0"	"203.8"	"243.0"	"913.0"	"160.3"	"152.6"	"79.6"	"1158.9"	"108.6"	"133.3"	"78.0"	"76.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P34932"	"Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4"	"40"	"30"	"54"	"27"	"840"	"94.3"	"5.19"	"10837.50"	"90.60"	"28"	"25"	"cell organization and biogenesis;stress response;transport;other biological processes"	"non-structural extracellular;cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf00012"	"3308"	"ENSG00000170606"	"HSPA4"	"hsa:3308; O95756; P34932; Q2TAL4; Q9BUK9"	"Regulation of HSF1-mediated heat shock response"	"Parkin-ubiquitin proteasomal system pathway"	"2"	"3"	"2197.6"	"2657.3"	"10042.0"	"2891.8"	"2439.5"	"1988.6"	"12247.5"	"1540.7"	"2144.4"	"1592.1"	"1504.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49368"	"T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4"	"48"	"25"	"49"	"25"	"545"	"60.5"	"6.49"	"8719.56"	"90.50"	"21"	"20"	"cell organization and biogenesis;transport;other biological processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00118"	"7203"	"ENSG00000163468"	"CCT3"	"A6NE14; hsa:7203; P49368; Q5SZY1; Q9BR64"	"Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; Folding of actin by CCT/TriC"	"16p11.2 proximal deletion syndrome"	"7"	"0"	"2577.1"	"2939.7"	"9006.1"	"2613.2"	"2301.6"	"1808.5"	"8965.6"	"1327.7"	"1871.5"	"1493.0"	"1584.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05455"	"Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2"	"55"	"24"	"57"	"24"	"408"	"46.8"	"7.12"	"11725.10"	"90.19"	"23"	"22"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf05383, Pf08777"	"6741"	"ENSG00000138385"	"SSB"	"hsa:6741; P05455; Q15367; Q53XJ4"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Termination"	""	"2"	"0"	"2861.9"	"3377.0"	"11000.7"	"3019.7"	"2892.3"	"2293.0"	"12908.3"	"2029.5"	"2888.5"	"2239.2"	"2173.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EK5"	"KIF-binding protein OS=Homo sapiens OX=9606 GN=KIFBP PE=1 SV=1"	"26"	"18"	"49"	"18"	"621"	"71.8"	"5.49"	"8794.32"	"89.74"	"15"	"16"	"cell organization and biogenesis;transport;developmental processes"	"cytoskeleton;mitochondrion"	"cytoskeletal activity"	"Pf12309"	"26128"	"ENSG00000198954"	"KIFBP"	"A8K5M8; hsa:26128; Q96EK5; Q9BR89; Q9ULE1; Q9Y428"	""	""	"0"	"0"	"780.2"	"727.6"	"2061.0"	"794.8"	"914.1"	"926.2"	"3336.2"	"2331.6"	"8320.9"	"8123.7"	"8517.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P02533"	"Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4"	"35"	"19"	"59"	"5"	"472"	"51.5"	"5.16"	"10670.03"	"88.90"	"17"	"18"	"cell organization and biogenesis;other biological processes"	"plasma membrane;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00038"	"3861"	"ENSG00000186847"	"KRT14"	"hsa:3861; P02533; Q14715; Q53XY3; Q9BUE3; Q9UBN2; Q9UBN3; Q9UCY4"	"Formation of the cornified envelope; Type I hemidesmosome assembly"	"Corticotropin-releasing hormone signaling pathway"	"4"	"3"	"4489.6"	"2292.6"	"1970.9"	"958.6"	"454.4"	"560.5"	"1314.7"	"382.3"	"364.9"	"310.3"	"360.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43776"	"Asparagine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=NARS1 PE=1 SV=1"	"35"	"21"	"47"	"21"	"548"	"62.9"	"6.25"	"10130.21"	"87.82"	"19"	"17"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00152, Pf01336"	"4677"	"ENSG00000134440"	"NARS1"	"B4DG16; hsa:4677; O43776; Q53GU6"	"Cytosolic tRNA aminoacylation"	"Photodynamic therapy-induced unfolded protein response"	"2"	"0"	"1117.9"	"1226.8"	"3545.6"	"1037.5"	"868.5"	"710.8"	"4487.5"	"994.7"	"2534.5"	"5358.2"	"10251.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q04837"	"Single-stranded DNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SSBP1 PE=1 SV=1"	"64"	"12"	"38"	"12"	"148"	"17.2"	"9.60"	"7445.51"	"84.46"	"9"	"12"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00436"	"6742"	"ENSG00000106028; ENSG00000262771"	"SSBP1"	"hsa:6742; Q04837"	"Transcriptional activation of mitochondrial biogenesis"	""	"1"	"0"	"1356.1"	"1867.6"	"4365.6"	"1815.3"	"1706.1"	"1440.4"	"8092.4"	"2265.2"	"3096.6"	"2215.2"	"2450.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12906"	"Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3"	"26"	"20"	"49"	"20"	"894"	"95.3"	"8.76"	"9269.30"	"83.96"	"19"	"20"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00035, Pf07528"	"3609"	"ENSG00000129351"	"ILF3"	"A8K6F2; G5E9M5; hsa:3609; O43409; Q12906; Q6P1X1; Q86XY7; Q99544; Q99545; Q9BZH4; Q9BZH5; Q9NQ95; Q9NQ96; Q9NQ97; Q9NQ98; Q9NQ99; Q9NQA0; Q9NQA1; Q9NQA2; Q9NRN2; Q9NRN3; Q9NRN4; Q9UMZ9; Q9UN00; Q9UN84; Q9UNA2"	"Regulation of CDH11 gene transcription"	""	"1"	"0"	"1961.1"	"1964.8"	"6520.7"	"1845.5"	"1750.9"	"1414.6"	"7494.5"	"853.3"	"1280.1"	"1009.4"	"1071.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P48643"	"T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1"	"41"	"23"	"51"	"23"	"541"	"59.6"	"5.66"	"11692.83"	"83.23"	"22"	"19"	"transport;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00118"	"22948"	"ENSG00000150753"	"CCT5"	"A8JZY8; A8K2X8; B4DYD8; hsa:22948; P48643"	"Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; Folding of actin by CCT/TriC"	"16p11.2 proximal deletion syndrome"	"7"	"0"	"4557.7"	"5040.5"	"15736.5"	"4704.0"	"3940.1"	"3320.7"	"15076.3"	"1891.6"	"2952.2"	"2442.8"	"2348.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52272"	"Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3"	"39"	"28"	"60"	"28"	"730"	"77.5"	"8.70"	"11160.22"	"83.06"	"27"	"22"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf11532"	"4670"	"ENSG00000099783"	"HNRNPM"	"hsa:4670; P52272; Q15584; Q8WZ44; Q96H56; Q9BWL9; Q9Y492"	"mRNA Splicing - Major Pathway; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA"	"mRNA processing"	"4"	"0"	"3096.2"	"3199.5"	"10792.8"	"2771.8"	"2542.9"	"2105.9"	"12473.2"	"1593.3"	"2384.7"	"2024.2"	"2366.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49327"	"Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3"	"11"	"20"	"40"	"20"	"2511"	"273.3"	"6.44"	"6644.91"	"81.15"	"16"	"19"	"other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00107, Pf00109, Pf00550, Pf00698, Pf00975, Pf02801, Pf08242, Pf08659, Pf14765, Pf16197"	"2194"	"ENSG00000169710"	"FASN"	"hsa:2194; P49327; Q13479; Q16702; Q4LE83; Q6P4U5; Q6SS02; Q969R1; Q96C68; Q96IT0"	"ChREBP activates metabolic gene expression; Activation of gene expression by SREBF (SREBP); Fatty acyl-CoA biosynthesis; NR1H2 & NR1H3 regulate gene expression linked to lipogenesis; Vitamin B5 (pantothenate) metabolism"	"AMP-activated protein kinase signaling; Sterol regulatory element-binding proteins (SREBP) signaling; SREBF and miR33 in cholesterol and lipid homeostasis; Liver X receptor pathway; Nuclear receptors meta-pathway; Fatty acid biosynthesis; Angiopoietin-like protein 8 regulatory pathway; Lipid metabolism pathway; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Omega-9 fatty acid synthesis; FOXA2 pathway"	"18"	"0"	"1008.9"	"1221.8"	"3996.3"	"1092.4"	"1041.0"	"858.2"	"5037.7"	"710.2"	"1049.1"	"800.7"	"833.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11908"	"Ribose-phosphate pyrophosphokinase 2 OS=Homo sapiens OX=9606 GN=PRPS2 PE=1 SV=2"	"47"	"15"	"45"	"3"	"318"	"34.7"	"6.61"	"9322.81"	"80.88"	"12"	"14"	"other metabolic processes;other biological processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf13793, Pf14572"	"5634"	"ENSG00000101911"	"PRPS2"	"hsa:5634; P11908; Q0VDH9; Q0VDI0; Q15245; Q2TAK7"	"5-Phosphoribose 1-diphosphate biosynthesis"	""	"1"	"0"	"131.3"	"234.5"	"518.8"	"238.2"	"247.8"	"224.1"	"576.7"	"190.7"	"434.1"	"511.1"	"695.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96AE4"	"Far upstream element-binding protein 1 OS=Homo sapiens OX=9606 GN=FUBP1 PE=1 SV=3"	"30"	"22"	"50"	"14"	"644"	"67.5"	"7.61"	"9259.55"	"80.63"	"21"	"20"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00013, Pf09005"	"8880"	"ENSG00000162613"	"FUBP1"	"hsa:8880; Q12828; Q96AE4"	""	""	"0"	"2"	"1304.9"	"1761.6"	"5885.4"	"1557.6"	"1594.0"	"1369.5"	"7469.3"	"1281.5"	"1731.4"	"1417.5"	"1630.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08865"	"40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4"	"48"	"14"	"33"	"14"	"295"	"32.8"	"4.87"	"5817.20"	"80.47"	"10"	"13"	"cell adhesion;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;translational apparatus;nucleus;other cell component"	"translation activity;other molecular function"	"Pf00318, Pf16122"	"3921"	"ENSG00000168028"	"RPSA"	"hsa:3921; P08865; P11085; P12030; Q16471; Q6IPD1; Q6IPD2; Q6NSD1; Q6NXQ8; Q86VC0"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"1235.1"	"1401.9"	"3767.0"	"1139.1"	"1148.0"	"921.3"	"4975.5"	"470.0"	"727.6"	"458.3"	"556.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P34897"	"Serine hydroxymethyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=SHMT2 PE=1 SV=3"	"32"	"15"	"42"	"14"	"504"	"56.0"	"8.53"	"7930.03"	"77.59"	"14"	"13"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00464"	"6472"	"ENSG00000182199"	"SHMT2"	"B7Z9F1; E7EQ19; E7EU43; hsa:6472; O00740; P34897; Q8N1A5"	"RHOG GTPase cycle; Metabolism of folate and pterines"	"Glycine metabolism; Vitamin B12 metabolism; Folate metabolism; One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Neuroinflammation and glutamatergic signaling"	"10"	"1"	"1212.8"	"1572.5"	"4869.1"	"1363.4"	"1218.5"	"1055.8"	"7913.1"	"1570.6"	"1913.8"	"1572.1"	"1553.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46777"	"60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3"	"48"	"14"	"44"	"14"	"297"	"34.3"	"9.72"	"10112.52"	"77.57"	"13"	"12"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf14204, Pf17144"	"6125"	"ENSG00000122406"	"RPL5"	"hsa:6125; P46777; Q32LZ3; Q53HH6; Q9H3F4"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"15"	"0"	"1856.1"	"2260.6"	"6889.8"	"1705.9"	"1741.5"	"1522.0"	"8979.5"	"1199.1"	"1757.3"	"1129.5"	"1141.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31948"	"Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1"	"46"	"29"	"61"	"29"	"543"	"62.6"	"6.80"	"11843.98"	"77.15"	"28"	"22"	"other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00515, Pf13181, Pf17830"	"10963"	"ENSG00000168439"	"STIP1"	"B4DM70; F5H0T1; G3XAD8; hsa:10963; P31948; Q3ZCU9; Q5TZU9"	"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; RND1 GTPase cycle"	"VEGFA-VEGFR2 signaling"	"3"	"0"	"3684.9"	"4940.5"	"17494.2"	"4622.9"	"3742.5"	"3264.9"	"18782.9"	"2193.0"	"2846.1"	"2496.4"	"2560.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P36578"	"60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5"	"55"	"28"	"63"	"28"	"427"	"47.7"	"11.06"	"13145.61"	"77.02"	"27"	"19"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00573, Pf14374"	"6124"	"ENSG00000174444"	"RPL4"	"A8K502; hsa:6124; P36578; P39029; Q4VBR0; Q969Z9"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"6373.3"	"6842.1"	"19662.2"	"5750.7"	"5493.7"	"4921.9"	"24027.6"	"2629.3"	"4072.4"	"2765.3"	"2536.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06576"	"ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3"	"34"	"16"	"45"	"16"	"529"	"56.5"	"5.40"	"9334.98"	"75.25"	"16"	"14"	"other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;mitochondrion;other cell component"	"signal transduction activity or receptor binding;transporter activity;other molecular function"	"Pf00006, Pf02874"	"506"	"ENSG00000110955"	"ATP5F1B"	"A8K4X0; hsa:506; P06576; Q14283"	"Transcriptional activation of mitochondrial biogenesis; Mitochondrial protein import; Cristae formation; Formation of ATP by chemiosmotic coupling"	"Electron transport chain: OXPHOS system in mitochondria; 7q11.23 copy number variation syndrome; Oxidative phosphorylation"	"7"	"0"	"1403.6"	"1501.3"	"5750.5"	"1372.2"	"1112.8"	"871.7"	"6175.5"	"743.7"	"1165.3"	"981.4"	"1049.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q05397"	"Focal adhesion kinase 1 OS=Homo sapiens OX=9606 GN=PTK2 PE=1 SV=2"	"18"	"14"	"31"	"14"	"1052"	"119.2"	"6.62"	"4884.34"	"74.88"	"9"	"14"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;kinase activity;other molecular function"	"Pf00373, Pf03623, Pf07714, Pf18038"	"5747"	"ENSG00000169398"	"PTK2"	"B4E2N6; F5H4S4; hsa:5747; J3QT16; Q05397; Q14291; Q8IYN9; Q9UD85"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; EPHB-mediated forward signaling; Signal regulatory protein family interactions; DCC mediated attractive signaling; RAF/MAP kinase cascade; VEGFA-VEGFR2 Pathway; Estrogen-dependent nuclear events downstream of ESR-membrane signaling; NCAM signaling for neurite out-growth; MET activates PTK2 signaling; GRB2:SOS provides linkage to MAPK signaling for Integrins ; p130Cas linkage to MAPK signaling for integrins; Apoptotic cleavage of cellular proteins"	"Androgen receptor signaling pathway; Integrin-mediated cell adhesion; RANKL/RANK signaling pathway; Leptin signaling pathway; Prolactin signaling pathway; Corticotropin-releasing hormone signaling pathway; Alpha 6 beta 4 signaling pathway; Primary focal segmental glomerulosclerosis (FSGS); Apoptosis-related network due to altered Notch3 in ovarian cancer; Focal adhesion; Hepatocyte growth factor receptor signaling; Overview of nanoparticle effects; MFAP5-mediated ovarian cancer cell motility and invasiveness; RAC1/PAK1/p38/MMP2 pathway; Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Prion disease pathway; PI3K-Akt signaling pathway; EGF/EGFR signaling pathway; Hippo-Merlin signaling dysregulation; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Small cell lung cancer; Gastrin signaling pathway; Netrin-UNC5B signaling pathway; Pleural mesothelioma; Regulation of actin cytoskeleton; 2q13 copy number variation syndrome; TROP2 regulatory signaling; A network map of Macrophage-stimulating protein (MSP) signaling; ErbB signaling pathway"	"48"	"0"	"489.4"	"498.0"	"1361.7"	"506.8"	"576.5"	"462.8"	"1895.8"	"1320.4"	"4629.0"	"4589.6"	"4753.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75390"	"Citrate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=CS PE=1 SV=2"	"35"	"16"	"49"	"16"	"466"	"51.7"	"8.32"	"8979.76"	"74.87"	"15"	"14"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00285"	"1431"	"ENSG00000062485"	"CS"	"hsa:1431; O75390; Q71UT9; Q7KZH0; Q96FZ8; Q9BWN8"	"Mitochondrial protein import; Citric acid cycle (TCA cycle)"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Fluoroacetic acid toxicity; TCA cycle (aka Krebs or citric acid cycle)"	"6"	"0"	"2620.5"	"2832.3"	"5430.5"	"2735.7"	"2595.4"	"2274.9"	"8688.5"	"3194.5"	"4201.4"	"3447.1"	"3779.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2L1"	"Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2"	"22"	"18"	"39"	"18"	"958"	"108.9"	"7.14"	"6264.33"	"74.84"	"15"	"17"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00773, Pf13638, Pf17215, Pf17216, Pf17849"	"22894"	"ENSG00000083520"	"DIS3"	"A6NI21; B2RBL2; hsa:22894; Q5W0P7; Q5W0P8; Q658Z7; Q7Z481; Q8WWI2; Q9UG36; Q9Y2L1"	"Major pathway of rRNA processing in the nucleolus and cytosol; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	""	"6"	"0"	"1353.8"	"1418.3"	"3983.6"	"1329.9"	"1229.0"	"1079.1"	"4747.9"	"836.1"	"1261.0"	"1145.1"	"1512.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63010"	"AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1"	"17"	"15"	"39"	"11"	"937"	"104.5"	"5.38"	"7364.59"	"74.53"	"14"	"14"	"transport;developmental processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01602, Pf02883, Pf09066"	"163"	"ENSG00000006125"	"AP2B1"	"A6NJP3; hsa:163; P21851; P63010; Q7Z451; Q96J19"	"Recycling pathway of L1; MHC class II antigen presentation; Potential therapeutics for SARS; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; LDL clearance; Nef Mediated CD4 Down-regulation; Retrograde neurotrophin signalling; Nef Mediated CD8 Down-regulation; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; VLDLR internalisation and degradation"	"Synaptic vesicle pathway; GABA receptor signaling; EGF/EGFR signaling pathway; Fragile X syndrome; mBDNF and proBDNF regulation of GABA neurotransmission; Markers of kidney cell lineage; 17q12 copy number variation syndrome"	"20"	"4"	"642.8"	"634.9"	"2249.8"	"639.9"	"623.0"	"541.6"	"2756.9"	"1474.3"	"4271.0"	"4910.1"	"5674.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P12277"	"Creatine kinase B-type OS=Homo sapiens OX=9606 GN=CKB PE=1 SV=1"	"40"	"14"	"34"	"14"	"381"	"42.6"	"5.59"	"4876.31"	"74.14"	"10"	"12"	"other metabolic processes;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00217, Pf02807"	"1152"	"ENSG00000166165"	"CKB"	"A8K236; B2R5R4; hsa:1152; P12277; Q2LE07; Q6FG40; Q9UC66"	"RND3 GTPase cycle; Creatine metabolism"	""	"2"	"0"	"1006.1"	"1337.9"	"6550.1"	"1130.2"	"999.3"	"663.8"	"7272.1"	"656.5"	"739.6"	"547.0"	"509.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14103"	"Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1"	"38"	"17"	"43"	"15"	"355"	"38.4"	"7.81"	"8086.42"	"73.39"	"15"	"16"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08143"	"3184"	"ENSG00000138668"	"HNRNPD"	"A8K9J2; hsa:3184; P07029; Q01858; Q14100; Q14101; Q14102; Q14103; Q4W5A1; Q9UCE8; Q9UCE9"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"mRNA processing"	"3"	"3"	"2184.1"	"2406.9"	"6749.2"	"2473.3"	"2272.2"	"1938.8"	"9647.0"	"1803.7"	"2765.1"	"2101.9"	"2130.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23246"	"Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2"	"28"	"20"	"41"	"19"	"707"	"76.1"	"9.44"	"7598.10"	"72.19"	"17"	"18"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08075"	"6421"	"ENSG00000116560"	"SFPQ"	"hsa:6421; P23246; P30808; Q5SZ71"	"Suppression of apoptosis; PTK6 Regulates Proteins Involved in RNA Processing"	"mRNA processing; Type 2 papillary renal cell carcinoma"	"4"	"1"	"2402.2"	"2471.7"	"5917.8"	"2676.0"	"2397.1"	"2281.6"	"6154.4"	"1031.3"	"1632.8"	"1241.3"	"1153.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TCS8"	"Polyribonucleotide nucleotidyltransferase 1, mitochondrial OS=Homo sapiens OX=9606 GN=PNPT1 PE=1 SV=2"	"31"	"18"	"39"	"18"	"783"	"85.9"	"7.77"	"7581.18"	"71.77"	"16"	"17"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"other membranes;cytosol;mitochondrion;ER/Golgi;translational apparatus;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf01138, Pf03725, Pf03726"	"87178"	"ENSG00000138035"	"PNPT1"	"hsa:87178; Q53SU0; Q68CN1; Q7Z7D1; Q8IWX1; Q8TCS8; Q96T05; Q9BRU3; Q9BVX0"	""	"Pyrimidine metabolism; miRNA degrading enzymes"	"2"	"0"	"1133.0"	"1169.7"	"2690.3"	"1110.4"	"1050.1"	"946.5"	"4409.7"	"1376.5"	"2042.2"	"1648.3"	"1776.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61247"	"40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2"	"65"	"23"	"49"	"23"	"264"	"29.9"	"9.73"	"9518.11"	"71.47"	"22"	"18"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01015"	"6189"	"ENSG00000145425"	"RPS3A"	"B2R4D4; D3DP05; hsa:6189; P33443; P49241; P61247"	"Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Peptide chain elongation; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"4191.8"	"4349.8"	"11815.4"	"3700.7"	"3376.2"	"3021.0"	"12965.2"	"1493.5"	"2333.2"	"1718.0"	"1638.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49588"	"Alanine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=AARS1 PE=1 SV=2"	"23"	"20"	"43"	"20"	"968"	"106.7"	"5.53"	"7081.12"	"71.41"	"17"	"18"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;mitochondrion;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01411, Pf02272, Pf07973"	"16"	"ENSG00000090861"	"AARS1"	"A6NF14; B4DR45; hsa:16; P49588; Q53GV7; Q96FA0"	"Cytosolic tRNA aminoacylation"	"IL-18 signaling pathway"	"2"	"0"	"2204.4"	"2553.5"	"10233.3"	"2334.1"	"1888.6"	"1362.4"	"11467.8"	"955.5"	"1276.6"	"1224.2"	"999.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51659"	"Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3"	"33"	"20"	"36"	"20"	"736"	"79.6"	"8.84"	"5892.76"	"71.41"	"16"	"17"	"other metabolic processes;developmental processes"	"cytosol;other cytoplasmic organelle"	"other molecular function"	"Pf00106, Pf01575, Pf02036"	"3295"	"ENSG00000133835"	"HSD17B4"	"B4DNV1; B4DVS5; E9PB82; F5HE57; hsa:3295; P51659"	"TYSND1 cleaves peroxisomal proteins; Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol; alpha-linolenic acid (ALA) metabolism; Beta-oxidation of pristanoyl-CoA; Beta-oxidation of very long chain fatty acids"	"Androgen receptor network in prostate cancer; Steroid biosynthesis; Disorders of bile acid synthesis and biliary transport; Primary ovarian insufficiency"	"10"	"0"	"1667.1"	"1699.9"	"4698.5"	"1499.9"	"1450.6"	"1269.9"	"4284.0"	"679.7"	"1083.3"	"1033.3"	"1270.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31943"	"Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4"	"23"	"10"	"30"	"3"	"449"	"49.2"	"6.30"	"5128.39"	"71.39"	"8"	"9"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08080"	"3187"	"ENSG00000169045; ENSG00000284254"	"HNRNPH1"	"B3KW86; D3DWQ2; hsa:3187; P31943; Q6IBM4"	"mRNA Splicing - Major Pathway; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA"	"MECP2 and associated Rett syndrome; mRNA processing; Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells"	"6"	"4"	"807.5"	"1604.7"	"4109.8"	"1345.7"	"1445.0"	"1357.2"	"5329.7"	"1089.4"	"1425.3"	"1078.4"	"1293.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62937"	"Peptidyl-prolyl cis-trans isomerase A OS=Homo sapiens OX=9606 GN=PPIA PE=1 SV=2"	"68"	"13"	"46"	"13"	"165"	"18.0"	"7.81"	"9336.47"	"71.02"	"11"	"11"	"cell adhesion;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00160"	"5478"	"ENSG00000196262"	"PPIA"	"A8K220; hsa:5478; P05092; P62937; Q3KQW3; Q567Q0; Q6IBU5; Q96IX3; Q9BRU4; Q9BTY9; Q9UC61"	"Neutrophil degranulation; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Budding and maturation of HIV virion; Platelet degranulation ; Basigin interactions; SARS-CoV-1 activates/modulates innate immune responses; Integration of provirus; APOBEC3G mediated resistance to HIV-1 infection; Calcineurin activates NFAT; Binding and entry of HIV virion; Assembly Of The HIV Virion; Uncoating of the HIV Virion; Minus-strand DNA synthesis; Plus-strand DNA synthesis"	"Prolactin signaling pathway"	"16"	"0"	"2570.1"	"3106.6"	"11858.7"	"2633.0"	"2099.0"	"1509.2"	"16778.6"	"2278.2"	"2224.7"	"1579.7"	"1583.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49407"	"Beta-arrestin-1 OS=Homo sapiens OX=9606 GN=ARRB1 PE=1 SV=2"	"32"	"14"	"38"	"11"	"418"	"47.0"	"6.20"	"7315.74"	"70.95"	"13"	"13"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00339, Pf02752"	"408"	"ENSG00000137486"	"ARRB1"	"B6V9G8; hsa:408; O75625; O75630; P49407; Q2PP20; Q9BTK8"	"Ub-specific processing proteases; Activation of SMO; Activated NOTCH1 Transmits Signal to the Nucleus; G alpha (s) signalling events; Lysosome Vesicle Biogenesis; Golgi Associated Vesicle Biogenesis; Signaling by BRAF and RAF1 fusions; Thrombin signalling through proteinase activated receptors (PARs); Cargo recognition for clathrin-mediated endocytosis; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants"	"Corticotropin-releasing hormone signaling pathway; Myometrial relaxation and contraction pathways; MAPK signaling pathway; Chemokine signaling pathway; Hedgehog signaling pathway; Gastrin signaling pathway; Kisspeptin/kisspeptin receptor system in the ovary; GPR143 in melanocytes and retinal pigment epithelium cells; Calcium regulation in cardiac cells"	"25"	"3"	"307.8"	"306.9"	"888.0"	"315.6"	"320.7"	"346.6"	"3645.6"	"2302.3"	"5416.4"	"4845.7"	"4927.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63104"	"14-3-3 protein zeta/delta OS=Homo sapiens OX=9606 GN=YWHAZ PE=1 SV=1"	"55"	"13"	"43"	"9"	"245"	"27.7"	"4.79"	"8828.51"	"70.80"	"13"	"11"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00244"	"7534"	"ENSG00000164924"	"YWHAZ"	"A8K1N0; B7Z465; hsa:7534; P29213; P29312; P63104; Q32P43; Q5XJ08; Q6GPI2; Q6IN74; Q6NUR9; Q6P3U9; Q86V33"	"RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Regulation of localization of FOXO transcription factors; Negative regulation of NOTCH4 signaling; Deactivation of the beta-catenin transactivating complex; Interleukin-3, Interleukin-5 and GM-CSF signaling; TP53 Regulates Metabolic Genes; NOTCH4 Activation and Transmission of Signal to the Nucleus; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; Rap1 signalling; KSRP (KHSRP) binds and destabilizes mRNA; GP1b-IX-V activation signalling; Activation of BAD and translocation to mitochondria"	"Cell cycle; Prolactin signaling pathway; Pathogenic Escherichia coli infection; Myometrial relaxation and contraction pathways; Hepatitis B infection; GDNF signaling; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"23"	"2"	"660.8"	"1004.9"	"5026.6"	"1015.5"	"935.7"	"846.4"	"6523.4"	"818.0"	"1157.1"	"970.6"	"959.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13797"	"Plastin-3 OS=Homo sapiens OX=9606 GN=PLS3 PE=1 SV=4"	"31"	"17"	"41"	"15"	"630"	"70.8"	"5.60"	"8485.03"	"70.43"	"16"	"16"	"cell organization and biogenesis;developmental processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf13499"	"5358"	"ENSG00000102024"	"PLS3"	"A8K579; B1AQ09; B4DGB4; B7Z6M1; hsa:5358; P13797; Q86YI6"	""	""	"0"	"2"	"886.7"	"1031.1"	"5423.6"	"1076.5"	"1023.6"	"796.1"	"7268.5"	"571.0"	"961.7"	"719.5"	"740.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UQ80"	"Proliferation-associated protein 2G4 OS=Homo sapiens OX=9606 GN=PA2G4 PE=1 SV=3"	"49"	"19"	"38"	"19"	"394"	"43.8"	"6.55"	"6384.06"	"68.83"	"17"	"16"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"non-structural extracellular;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00557"	"5036"	"ENSG00000170515"	"PA2G4"	"hsa:5036; O43846; Q9UM59; Q9UQ80"	"Neutrophil degranulation"	""	"1"	"0"	"1670.0"	"1728.9"	"5822.4"	"1746.2"	"1347.5"	"1127.6"	"6695.9"	"1143.9"	"1709.5"	"1651.0"	"1810.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P47897"	"Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1"	"25"	"16"	"40"	"15"	"775"	"87.7"	"7.15"	"7295.98"	"68.49"	"14"	"16"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;mitochondrion;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00749, Pf03950, Pf04557, Pf04558"	"5859"	"ENSG00000172053"	"QARS1"	"B4DWJ2; hsa:5859; P47897"	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation; Mitochondrial tRNA aminoacylation"	""	"3"	"0"	"792.3"	"1061.7"	"3197.7"	"1128.3"	"1014.6"	"797.9"	"2702.9"	"429.1"	"690.8"	"544.1"	"595.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00571"	"ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3"	"29"	"21"	"42"	"21"	"662"	"73.2"	"7.18"	"7774.73"	"68.46"	"19"	"18"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;translation activity;nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"1654"	"ENSG00000215301"	"DDX3X"	"A8K538; B4E3E8; hsa:1654; O00571; O15536"	"Neutrophil degranulation"	"Novel intracellular components of RIG-I-like receptor pathway; Hepatitis B infection"	"3"	"0"	"1819.3"	"1776.9"	"4501.6"	"1768.0"	"1545.5"	"1436.1"	"4923.8"	"915.0"	"1363.4"	"1127.2"	"1206.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30101"	"Protein disulfide-isomerase A3 OS=Homo sapiens OX=9606 GN=PDIA3 PE=1 SV=4"	"36"	"17"	"35"	"17"	"505"	"56.7"	"6.35"	"6759.09"	"68.33"	"16"	"15"	"cell adhesion;cell organization and biogenesis;stress response;signal transduction;other biological processes"	"non-structural extracellular;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00085, Pf13848"	"2923"	"ENSG00000167004"	"PDIA3"	"hsa:2923; P30101; Q13453; Q14255; Q8IYF8; Q9UMU7"	"ER-Phagosome pathway; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Calnexin/calreticulin cycle"	"Prion disease pathway"	"4"	"0"	"1451.8"	"1484.5"	"4907.7"	"1640.0"	"1181.8"	"826.5"	"6854.3"	"785.9"	"1300.1"	"1134.8"	"1069.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P40227"	"T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3"	"39"	"18"	"39"	"18"	"531"	"58.0"	"6.68"	"7463.94"	"68.31"	"15"	"15"	"other biological processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00118"	"908"	"ENSG00000146731"	"CCT6A"	"A6NCD2; hsa:908; P40227; Q3KP28; Q75LP4; Q96S46"	"Formation of tubulin folding intermediates by CCT/TriC; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; RHOBTB2 GTPase cycle; Folding of actin by CCT/TriC"	"16p11.2 proximal deletion syndrome"	"7"	"0"	"2743.0"	"3277.5"	"9378.2"	"2661.4"	"2201.6"	"1834.4"	"9490.7"	"1440.6"	"1920.6"	"1748.0"	"1792.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43175"	"D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4"	"33"	"16"	"40"	"16"	"533"	"56.6"	"6.71"	"8698.22"	"67.97"	"14"	"14"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;developmental processes;other biological processes"	"cytosol"	"other molecular function"	"Pf00389, Pf02826, Pf19304"	"26227"	"ENSG00000092621"	"PHGDH"	"B2RD08; hsa:26227; O43175; Q5SZU3; Q9BQ01"	"Serine biosynthesis"	"Trans-sulfuration, one-carbon metabolism and related pathways; Clear cell renal cell carcinoma pathways; Neuroinflammation and glutamatergic signaling; Amino acid metabolism in triple-negative breast cancer cells"	"5"	"0"	"2380.9"	"2370.8"	"10263.8"	"2064.2"	"1602.6"	"1277.5"	"10361.1"	"781.9"	"1228.7"	"932.7"	"909.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11177"	"Pyruvate dehydrogenase E1 component subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=PDHB PE=1 SV=3"	"38"	"12"	"37"	"12"	"359"	"39.2"	"6.65"	"7813.02"	"67.80"	"11"	"12"	"other metabolic processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf02779, Pf02780"	"5162"	"ENSG00000168291"	"PDHB"	"B2R7L0; B4DDD7; hsa:5162; P11177; Q6FH45; Q9BQ27; Q9UFK3"	"Glyoxylate metabolism and glycine degradation; Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid"	"Metabolic reprogramming in colon cancer; Orexin receptor pathway"	"6"	"0"	"1574.9"	"1626.4"	"3953.1"	"1911.8"	"1533.0"	"1451.0"	"4754.4"	"962.5"	"1457.6"	"993.5"	"940.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60174"	"Triosephosphate isomerase OS=Homo sapiens OX=9606 GN=TPI1 PE=1 SV=3"	"54"	"17"	"39"	"17"	"286"	"30.8"	"5.92"	"8405.14"	"67.54"	"16"	"14"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf00121"	""	"ENSPPYG00000004207; ENSPTRG00000004595"	"TPI1"	"A0A2J8JEI5; A0A2J8JEJ3; A0A2J8TBG7; A0A6D2X563; H2NGA4"	""	""	"0"	"0"	"1807.9"	"2093.3"	"10392.3"	"1964.3"	"1575.6"	"1013.4"	"15823.4"	"1270.4"	"1431.8"	"1031.7"	"810.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60842"	"Eukaryotic initiation factor 4A-I OS=Homo sapiens OX=9606 GN=EIF4A1 PE=1 SV=1"	"48"	"17"	"39"	"7"	"406"	"46.1"	"5.48"	"9265.51"	"67.52"	"14"	"13"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"1973"	"ENSG00000161960"	"EIF4A1"	"B2R6L8; D3DTP9; hsa:1973; J3QLC4; P04765; P60842; Q5U018; Q61516"	"L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Translation initiation complex formation; Ribosomal scanning and start codon recognition; Deadenylation of mRNA; ISG15 antiviral mechanism"	"Translation factors; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Interferon type I signaling pathways"	"11"	"11"	"1862.0"	"2278.3"	"6966.2"	"2341.2"	"2209.7"	"1825.8"	"8529.5"	"1367.2"	"1933.7"	"1662.0"	"1662.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HB71"	"Calcyclin-binding protein OS=Homo sapiens OX=9606 GN=CACYBP PE=1 SV=2"	"50"	"14"	"36"	"14"	"228"	"26.2"	"8.25"	"7251.08"	"67.52"	"13"	"13"	"developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf04969, Pf05002, Pf09032"	"27101"	"ENSG00000116161"	"CACYBP"	"B2ZWH2; B3KSF1; hsa:27101; O60666; Q5R370; Q5R371; Q9HB71"	""	"Gastric cancer network 2"	"1"	"0"	"1415.1"	"1422.0"	"5005.2"	"1483.6"	"1119.2"	"957.1"	"4552.1"	"1187.5"	"2537.6"	"4483.1"	"7901.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11940"	"Polyadenylate-binding protein 1 OS=Homo sapiens OX=9606 GN=PABPC1 PE=1 SV=2"	"29"	"17"	"42"	"12"	"636"	"70.6"	"9.50"	"8003.15"	"67.36"	"16"	"16"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf00658"	"26986"	"ENSG00000070756"	"PABPC1"	"hsa:26986; P11940; Q15097; Q93004"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; AUF1 (hnRNP D0) binds and destabilizes mRNA; Regulation of expression of SLITs and ROBOs; Deadenylation of mRNA; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Translation factors; Endoderm differentiation; VEGFA-VEGFR2 signaling; Acute viral myocarditis"	"11"	"5"	"2130.9"	"2352.5"	"7691.7"	"2148.2"	"2088.7"	"1715.1"	"9399.5"	"1153.2"	"1752.3"	"1308.6"	"1429.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P39023"	"60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2"	"47"	"23"	"45"	"23"	"403"	"46.1"	"10.18"	"7765.67"	"66.48"	"19"	"15"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00297"	"6122"	"ENSG00000100316"	"RPL3"	"B2RDV9; hsa:6122; P39023; Q15548; Q5I0G0"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"5925.1"	"6091.5"	"18991.5"	"5727.7"	"5069.7"	"4528.2"	"20694.6"	"1857.9"	"3078.3"	"2096.0"	"1888.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52597"	"Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3"	"24"	"12"	"29"	"9"	"415"	"45.6"	"5.58"	"3701.34"	"66.28"	"8"	"12"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf08080"	"3185"	"ENSG00000169813"	"HNRNPF"	"B3KM84; hsa:3185; P52597; Q5T0N2; Q96AU2"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA; FGFR2 alternative splicing; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	"MECP2 and associated Rett syndrome"	"5"	"3"	"767.6"	"2537.8"	"4951.0"	"2397.2"	"2428.6"	"2462.8"	"4784.7"	"1354.4"	"1840.8"	"1316.1"	"1535.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08559"	"Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial OS=Homo sapiens OX=9606 GN=PDHA1 PE=1 SV=3"	"33"	"15"	"41"	"15"	"390"	"43.3"	"8.06"	"8913.17"	"66.26"	"13"	"14"	"other metabolic processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00676"	"5160"	"ENSG00000131828"	"PDHA1"	"A5YVE9; B2R5P7; B7Z3T7; B7Z3X5; hsa:5160; P08559; Q53H41; Q5JPT8; Q9NP12; Q9UBJ8; Q9UBU0; Q9UNG4; Q9UNG5"	"Glyoxylate metabolism and glycine degradation; Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Lipid metabolism pathway; PI3K/AKT/mTOR - vitamin D3 signaling; Metabolic reprogramming in colon cancer; Thiamine metabolic pathways; TCA cycle in senescence; Neuroinflammation and glutamatergic signaling; Acetylcholine synthesis; Glycolysis and gluconeogenesis"	"14"	"0"	"2597.6"	"2823.1"	"6055.9"	"3171.2"	"2690.6"	"2527.1"	"7977.6"	"2214.5"	"3095.2"	"2199.5"	"2275.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22314"	"Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3"	"16"	"16"	"41"	"16"	"1058"	"117.8"	"5.76"	"9531.74"	"65.75"	"16"	"14"	"protein metabolism;other metabolic processes;stress response"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00899, Pf09358, Pf10585, Pf16190, Pf16191"	"7317"	"ENSG00000130985"	"UBA1"	"hsa:7317; P22314; Q5JRR8; Q96E13"	"Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Antigen processing: Ubiquitination & Proteasome degradation"	"Proteasome degradation; Parkin-ubiquitin proteasomal system pathway; Parkinson's disease pathway"	"5"	"0"	"1287.5"	"1477.5"	"7258.8"	"1367.3"	"1229.3"	"861.3"	"10104.1"	"875.5"	"1142.1"	"843.7"	"785.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92841"	"Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2"	"28"	"19"	"38"	"14"	"729"	"80.2"	"8.27"	"6947.05"	"65.34"	"17"	"17"	"RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"10521"	"ENSG00000100201"	"DDX17"	"B1AHM0; H3BLZ8; hsa:10521; Q69YT1; Q6ICD6; Q92841"	"SUMOylation of transcription cofactors"	"Novel intracellular components of RIG-I-like receptor pathway"	"2"	"5"	"1494.0"	"1507.0"	"4379.4"	"1507.2"	"1409.2"	"1228.1"	"4712.4"	"723.8"	"1009.1"	"1501.0"	"833.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35579"	"Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4"	"13"	"21"	"38"	"16"	"1960"	"226.4"	"5.60"	"7102.67"	"65.03"	"19"	"19"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00063, Pf01576, Pf02736"	"4627"	"ENSG00000100345"	"MYH9"	"A8K6E4; hsa:4627; O60805; P35579; Q60FE2; Q86T83"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Signaling by ALK fusions and activated point mutants; RHO GTPases activate CIT; EPHA-mediated growth cone collapse; Sema4D induced cell migration and growth-cone collapse; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; RHO GTPases activate PAKs; CD163 mediating an anti-inflammatory response"	"Primary focal segmental glomerulosclerosis (FSGS); VEGFA-VEGFR2 signaling; Nephrotic syndrome"	"16"	"4"	"1600.1"	"1606.8"	"7453.1"	"1389.0"	"923.6"	"724.4"	"4840.4"	"489.0"	"720.6"	"671.8"	"585.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P27348"	"14-3-3 protein theta OS=Homo sapiens OX=9606 GN=YWHAQ PE=1 SV=1"	"48"	"11"	"36"	"8"	"245"	"27.7"	"4.78"	"7457.46"	"63.90"	"11"	"9"	"transport;signal transduction;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00244"	"10971"	"ENSG00000134308"	"YWHAQ"	"D6W4Z5; hsa:10971; P27348; Q567U5; Q5TZU8; Q9UP48"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Regulation of localization of FOXO transcription factors; TP53 Regulates Metabolic Genes; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Activation of BAD and translocation to mitochondria"	"Cell cycle; Pathogenic Escherichia coli infection; Primary focal segmental glomerulosclerosis (FSGS); IL-3 signaling pathway; Myometrial relaxation and contraction pathways; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-YAP signaling; Leukocyte-intrinsic Hippo pathway functions; Hepatitis B infection; Opioid receptor pathways; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"20"	"0"	"675.7"	"1048.2"	"3893.8"	"1040.9"	"1008.6"	"932.5"	"4871.6"	"774.0"	"1186.4"	"1055.4"	"1105.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60506"	"Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2"	"33"	"18"	"37"	"11"	"623"	"69.6"	"8.59"	"6797.91"	"63.85"	"15"	"16"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf18360"	"10492"	"ENSG00000135316"	"SYNCRIP"	"E1P501; E1P502; hsa:10492; O60506; Q53H05; Q5TCG2; Q5TCG3; Q8IW78; Q8N599; Q96LC1; Q96LC2; Q9Y583"	""	""	"0"	"7"	"1663.7"	"1734.0"	"6259.0"	"1673.7"	"1549.5"	"1258.7"	"7990.4"	"831.6"	"1298.5"	"989.7"	"918.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P2T1"	"GMP reductase 2 OS=Homo sapiens OX=9606 GN=GMPR2 PE=1 SV=1"	"42"	"10"	"25"	"9"	"348"	"37.9"	"7.23"	"2736.61"	"63.08"	"6"	"9"	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00478"	"51292"	"ENSG00000100938; ENSG00000284752"	"GMPR2"	"D3DS66; hsa:51292; Q567T0; Q6IAJ8; Q86T14; Q9P2T1"	"Purine salvage"	""	"1"	"1"	"298.9"	"271.9"	"930.7"	"277.3"	"307.3"	"251.0"	"1390.6"	"616.3"	"2964.6"	"4458.1"	"6812.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P41252"	"Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2"	"16"	"19"	"41"	"19"	"1262"	"144.4"	"6.15"	"9115.64"	"62.95"	"19"	"17"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00133, Pf08264, Pf19302"	"3376"	"ENSG00000196305"	"IARS1"	"A8KAE9; hsa:3376; P41252; Q5TCD0; Q7Z3T4; Q9H588"	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"Amino acid metabolism"	"3"	"0"	"2236.6"	"2331.9"	"9240.3"	"1926.8"	"1622.6"	"1134.8"	"8139.8"	"753.2"	"1333.1"	"989.7"	"1081.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q02790"	"Peptidyl-prolyl cis-trans isomerase FKBP4 OS=Homo sapiens OX=9606 GN=FKBP4 PE=1 SV=3"	"45"	"17"	"32"	"17"	"459"	"51.8"	"5.43"	"5440.26"	"62.27"	"12"	"15"	"cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00254, Pf00515"	"2288"	"ENSG00000004478"	"FKBP4"	"D3DUQ1; hsa:2288; Q02790; Q9UCP1; Q9UCV7"	"Estrogen-dependent gene expression; Potential therapeutics for SARS; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Attenuation phase"	"Androgen receptor signaling pathway"	"6"	"0"	"1508.9"	"1675.0"	"5955.0"	"1720.4"	"1394.3"	"1053.3"	"7308.3"	"960.6"	"1449.5"	"1154.5"	"1110.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49321"	"Nuclear autoantigenic sperm protein OS=Homo sapiens OX=9606 GN=NASP PE=1 SV=2"	"27"	"20"	"41"	"19"	"788"	"85.2"	"4.30"	"7959.45"	"60.95"	"18"	"16"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf10516"	"4678"	"ENSG00000132780"	"NASP"	"A8K6H2; B4DQP3; D3DQ07; F5H3J2; hsa:4678; P49321; Q53GW5; Q5T622; Q5T625; Q96A69; Q9BTW2"	""	""	"0"	"1"	"1905.1"	"2468.1"	"8248.1"	"2398.5"	"2083.1"	"2029.8"	"9448.6"	"1304.0"	"1721.0"	"1463.1"	"1272.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P32121"	"Beta-arrestin-2 OS=Homo sapiens OX=9606 GN=ARRB2 PE=1 SV=2"	"34"	"14"	"31"	"11"	"409"	"46.1"	"7.69"	"5655.48"	"60.93"	"13"	"13"	"cell-cell signaling;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00339, Pf02752"	"409"	"ENSG00000141480"	"ARRB2"	"B4DLW0; B5B0C0; B7WPL3; D3DTK2; H0Y688; hsa:409; P32121; Q0Z8D3; Q2PP19; Q6ICT3; Q8N7Y2; Q9UEQ6"	"Ub-specific processing proteases; Activated NOTCH1 Transmits Signal to the Nucleus; Cargo recognition for clathrin-mediated endocytosis; Activation of SMO; G alpha (s) signalling events; Signaling by BRAF and RAF1 fusions; Thrombin signalling through proteinase activated receptors (PARs); WNT5A-dependent internalization of FZD4; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants"	"Corticotropin-releasing hormone signaling pathway; Complement system; Myometrial relaxation and contraction pathways; Wnt signaling pathway; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Hedgehog signaling pathway; Gastrin signaling pathway; Kisspeptin/kisspeptin receptor system in the ovary; GPR143 in melanocytes and retinal pigment epithelium cells; Calcium regulation in cardiac cells"	"27"	"0"	"286.0"	"294.0"	"890.2"	"298.1"	"281.2"	"257.8"	"2918.1"	"1954.1"	"3936.1"	"3655.9"	"3900.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06748"	"Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2"	"46"	"17"	"47"	"17"	"294"	"32.6"	"4.78"	"9233.60"	"60.75"	"16"	"15"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;translation activity;nucleic acid binding activity;other molecular function"	"Pf03066, Pf16276"	"4869"	"ENSG00000181163"	"NPM1"	"A8K3N7; B5BU00; D3DQL6; hsa:4869; P06748; P08693; Q12826; Q13440; Q13441; Q14115; Q5EU94; Q5EU95; Q5EU96; Q5EU97; Q5EU98; Q5EU99; Q6V962; Q8WTW5; Q96AT6; Q96DC4; Q96EA5; Q9BYG9; Q9UDJ7"	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain; Nuclear import of Rev protein; Deposition of new CENPA-containing nucleosomes at the centromere; SUMOylation of transcription cofactors; ALK mutants bind TKIs; Nuclear events stimulated by ALK signaling in cancer; TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation; SARS-CoV-1-host interactions"	""	"9"	"0"	"4089.5"	"4505.7"	"12554.1"	"4143.4"	"3237.1"	"2861.4"	"20864.1"	"4729.8"	"7662.3"	"6274.5"	"8264.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13263"	"Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5"	"17"	"16"	"34"	"16"	"835"	"88.5"	"5.77"	"7113.51"	"60.41"	"15"	"14"	"cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00628, Pf00643, Pf14634"	"10155"	"ENSG00000130726"	"TRIM28"	"hsa:10155; O00677; Q13263; Q7Z632; Q93040; Q96IM1"	"HCMV Early Events; Generic Transcription Pathway; SUMOylation of transcription cofactors"	"Corticotropin-releasing hormone signaling pathway; Mesodermal commitment pathway; ATM signaling in development and disease"	"6"	"0"	"1709.4"	"1935.2"	"8343.5"	"1750.1"	"1394.0"	"1045.3"	"9112.2"	"698.2"	"1006.7"	"786.6"	"842.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99497"	"Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2"	"69"	"12"	"33"	"12"	"189"	"19.9"	"6.79"	"6334.78"	"60.38"	"10"	"11"	"cell-cell signaling;cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf01965"	"11315"	"ENSG00000116288"	"PARK7"	"B2R4Z1; hsa:11315; O14805; Q6DR95; Q7LFU2; Q99497"	"Aggrephagy; Late endosomal microautophagy; SUMOylation of transcription cofactors; Chaperone Mediated Autophagy"	"Androgen receptor signaling pathway; Synaptic vesicle pathway; Parkinson's disease pathway"	"7"	"0"	"2132.5"	"2227.9"	"5050.1"	"2161.1"	"1992.2"	"1892.7"	"5920.8"	"1755.0"	"2260.9"	"1821.9"	"1999.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92499"	"ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2"	"32"	"17"	"32"	"17"	"740"	"82.4"	"7.23"	"6034.92"	"58.53"	"14"	"15"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf00622"	"1653"	"ENSG00000079785"	"DDX1"	"B4DME8; B4DPN6; hsa:1653; Q92499"	"tRNA processing in the nucleus"	"DDX1 as a regulatory component of the Drosha microprocessor; mRNA processing"	"3"	"0"	"1339.7"	"1293.2"	"3676.3"	"1342.8"	"1166.6"	"956.4"	"3242.5"	"476.9"	"707.3"	"613.2"	"602.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15233"	"Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4"	"32"	"15"	"35"	"14"	"471"	"54.2"	"8.95"	"5928.22"	"58.35"	"13"	"14"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08075"	"4841"	"ENSG00000147140"	"NONO"	"B7Z4C2; D3DVV4; F5GYZ3; hsa:4841; O00201; P30807; Q12786; Q15233; Q9BQC5"	""	"mRNA processing"	"1"	"0"	"2005.7"	"2035.4"	"4655.4"	"2164.8"	"1887.7"	"1838.6"	"4670.1"	"901.6"	"1589.9"	"1413.1"	"1473.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P0DP25"	"Calmodulin-3 OS=Homo sapiens OX=9606 GN=CALM3 PE=1 SV=1"	"77"	"13"	"34"	"13"	"149"	"16.8"	"4.22"	"6269.59"	"58.27"	"10"	"13"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;mitochondrion;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf13499"	"801; 805; 808"	"ENSG00000160014"	"CALM3"	"hsa:801; hsa:805; hsa:808; P02593; P0DP25; P62158; P70667; P99014; Q13942; Q53S29; Q61379; Q61380; Q96HK3"	""	"Physiological and pathological hypertrophy of the heart; MicroRNAs in cardiomyocyte hypertrophy; Alzheimer's disease and miRNA effects; T cell receptor and co-stimulatory signaling; Cardiac hypertrophic response; Myometrial relaxation and contraction pathways; G protein signaling pathways; Ras signaling; Melanoma; Endochondral ossification; Endochondral ossification with skeletal dysplasias; CAMKK2 pathway; Glycogen synthesis and degradation; Neuroinflammation and glutamatergic signaling; Alzheimer's disease; G13 signaling pathway; Calcium regulation in cardiac cells"	"17"	"0"	"1007.8"	"1744.7"	"4115.7"	"1420.4"	"1261.4"	"1221.8"	"5079.5"	"1076.4"	"1566.3"	"1540.4"	"2748.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15366"	"Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1"	"39"	"10"	"25"	"5"	"365"	"38.6"	"6.79"	"4580.83"	"58.09"	"7"	"10"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013"	"5094"	"ENSG00000197111"	"PCBP2"	"A8K7X6; B4DXP5; F8VYL7; G3V0E8; hsa:5094; I6L8F9; Q15366; Q32Q82; Q59HD4; Q68Y55; Q6IPF4; Q6PKG5"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA; Negative regulators of DDX58/IFIH1 signaling; SARS-CoV-1 activates/modulates innate immune responses"	"mRNA processing; Ferroptosis; Modulators of TCR signaling and T cell activation"	"7"	"0"	"397.9"	"540.5"	"2284.9"	"480.3"	"420.6"	"308.0"	"2670.6"	"264.9"	"326.4"	"301.7"	"378.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P18124"	"60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1"	"56"	"16"	"39"	"16"	"248"	"29.2"	"10.65"	"7786.85"	"57.86"	"16"	"12"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00327, Pf08079"	"6129"	"ENSG00000147604"	"RPL7"	"A8K504; hsa:6129; P18124; Q15289; Q3KQU0; Q5I0X1; Q6IBM9"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"15"	"0"	"1947.4"	"2172.2"	"6720.0"	"1929.4"	"1767.8"	"1537.5"	"7648.6"	"802.0"	"1220.2"	"773.8"	"784.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60256"	"Phosphoribosyl pyrophosphate synthase-associated protein 2 OS=Homo sapiens OX=9606 GN=PRPSAP2 PE=1 SV=1"	"49"	"16"	"31"	"13"	"369"	"40.9"	"7.44"	"5230.03"	"57.54"	"14"	"14"	"other metabolic processes;developmental processes"	"other cell component"	"enzyme regulator activity;other molecular function"	"Pf13793, Pf14572"	"5636"	"ENSG00000141127"	"PRPSAP2"	"B4E1M8; B4E329; B7ZKZ1; E7EMY2; hsa:5636; O60256; Q6IAS2"	""	""	"0"	"3"	"900.5"	"1135.8"	"2867.4"	"1309.7"	"1062.9"	"1070.7"	"2973.8"	"846.6"	"2624.9"	"3228.4"	"4746.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04843"	"Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1"	"29"	"15"	"30"	"15"	"607"	"68.5"	"6.38"	"5792.40"	"56.92"	"13"	"13"	"protein metabolism;other metabolic processes"	"other membranes;cytosol;ER/Golgi;other cell component"	""	"Pf04597"	"6184"	"ENSG00000163902"	"RPN1"	"B2R5Z0; D3DNB6; hsa:6184; P04843; Q68DT1"	"SRP-dependent cotranslational protein targeting to membrane; Asparagine N-linked glycosylation; Maturation of spike protein"	"Proteasome degradation; N-glycan biosynthesis"	"5"	"0"	"1254.9"	"1281.0"	"4910.6"	"1117.5"	"991.5"	"740.1"	"5270.4"	"512.0"	"837.1"	"645.4"	"770.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86VP6"	"Cullin-associated NEDD8-dissociated protein 1 OS=Homo sapiens OX=9606 GN=CAND1 PE=1 SV=2"	"12"	"13"	"32"	"13"	"1230"	"136.3"	"5.78"	"6407.31"	"56.76"	"13"	"13"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf08623"	"55832"	"ENSG00000111530"	"CAND1"	"B2RAU3; hsa:55832; O94918; Q6PIY4; Q86VP6; Q8NDJ4; Q96JZ9; Q96T19; Q9BTC4; Q9H0G2; Q9P0H7; Q9UF85"	"Neutrophil degranulation; Neddylation; Iron uptake and transport"	"Endoderm differentiation"	"4"	"0"	"951.5"	"1022.8"	"4215.3"	"1084.2"	"835.5"	"667.8"	"4115.0"	"481.8"	"724.6"	"645.8"	"772.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15371"	"Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1"	"26"	"10"	"25"	"10"	"548"	"63.9"	"6.05"	"3680.22"	"56.16"	"6"	"9"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf05091"	"8664"	"ENSG00000100353"	"EIF3D"	"A8MWD3; B2R7D4; B4DTF8; B4DVY1; hsa:8664; O15371; Q3MJD9; Q5M9Q6"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"Translation factors; VEGFA-VEGFR2 signaling; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"9"	"0"	"700.1"	"719.2"	"2304.0"	"741.2"	"695.1"	"585.1"	"2545.6"	"321.2"	"552.9"	"455.3"	"468.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94973"	"AP-2 complex subunit alpha-2 OS=Homo sapiens OX=9606 GN=AP2A2 PE=1 SV=2"	"21"	"14"	"26"	"11"	"939"	"103.9"	"6.96"	"4650.69"	"55.46"	"10"	"13"	"transport"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01602, Pf02296, Pf02883"	"161"	"ENSG00000183020"	"AP2A2"	"hsa:161; O75403; O94973; Q53ET1; Q96SI8"	"Neutrophil degranulation; Potential therapeutics for SARS; Recycling pathway of L1; MHC class II antigen presentation; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; LDL clearance; Nef Mediated CD4 Down-regulation; Retrograde neurotrophin signalling; Nef Mediated CD8 Down-regulation; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; VLDLR internalisation and degradation"	"Synaptic vesicle pathway; GABA receptor signaling; mBDNF and proBDNF regulation of GABA neurotransmission"	"17"	"3"	"465.7"	"395.7"	"1290.2"	"401.2"	"391.4"	"366.0"	"1552.2"	"953.8"	"2716.5"	"3030.4"	"3580.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NSD9"	"Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3"	"31"	"17"	"33"	"17"	"589"	"66.1"	"6.84"	"6055.25"	"55.25"	"15"	"15"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03483, Pf03484, Pf17759, Pf18262"	"10056"	"ENSG00000116120"	"FARSB"	"B4DFM0; hsa:10056; O95708; Q4ZFX1; Q57ZJ5; Q9NSD9; Q9NZZ6"	"Cytosolic tRNA aminoacylation"	"VEGFA-VEGFR2 signaling; Amino acid metabolism"	"3"	"0"	"2042.7"	"2081.5"	"5350.2"	"1954.7"	"1902.0"	"1703.0"	"5527.8"	"800.3"	"1135.5"	"916.1"	"800.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07737"	"Profilin-1 OS=Homo sapiens OX=9606 GN=PFN1 PE=1 SV=2"	"56"	"8"	"30"	"8"	"140"	"15.0"	"8.27"	"6668.55"	"55.22"	"8"	"8"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00235"	"5216"	"ENSG00000108518"	"PFN1"	"hsa:5216; P07737; Q53Y44"	"RHO GTPases Activate Formins; Platelet degranulation ; PCP/CE pathway; Signaling by ROBO receptors"	"Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; Burn wound healing; Regulation of actin cytoskeleton; G13 signaling pathway"	"9"	"0"	"547.7"	"607.6"	"6742.5"	"677.7"	"532.5"	"330.8"	"9489.7"	"423.4"	"538.8"	"378.4"	"353.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P26373"	"60S ribosomal protein L13 OS=Homo sapiens OX=9606 GN=RPL13 PE=1 SV=4"	"44"	"13"	"37"	"13"	"211"	"24.2"	"11.65"	"6151.85"	"55.18"	"11"	"11"	"protein metabolism;other metabolic processes;developmental processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01294"	"6137"	"ENSG00000167526"	"RPL13"	"B4DLX3; F5H1S2; hsa:6137; P26373; Q3KQT8; Q567Q8; Q9BPX0"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"3153.3"	"3487.9"	"9693.0"	"2925.4"	"2684.0"	"2449.1"	"11098.5"	"1240.1"	"1914.9"	"1324.5"	"1252.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05388"	"60S acidic ribosomal protein P0 OS=Homo sapiens OX=9606 GN=RPLP0 PE=1 SV=1"	"38"	"11"	"30"	"11"	"317"	"34.3"	"5.97"	"6083.15"	"54.80"	"10"	"10"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00428, Pf00466, Pf17777"	"6175"	"ENSG00000089157"	"RPLP0"	"hsa:6175; P05388; Q3B7A4; Q9BVK4"	"Regulation of expression of SLITs and ROBOs; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"15"	"0"	"2349.8"	"2493.6"	"9359.8"	"2377.0"	"1929.8"	"1649.7"	"7866.6"	"617.1"	"927.8"	"653.6"	"614.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q04637"	"Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4"	"12"	"17"	"36"	"15"	"1599"	"175.4"	"5.33"	"6900.58"	"54.19"	"17"	"14"	"protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02020, Pf02847, Pf02854"	"1981"	"ENSG00000114867"	"EIF4G1"	"D3DNT2; D3DNT4; D3DNT5; E9PFM1; G5E9S1; hsa:1981; O43177; O95066; Q04637; Q5HYG0; Q6ZN21; Q8N102"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); AUF1 (hnRNP D0) binds and destabilizes mRNA; Deadenylation of mRNA; ISG15 antiviral mechanism; mTORC1-mediated signalling"	"Translation factors; VEGFA-VEGFR2 signaling; Acute viral myocarditis; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Pleural mesothelioma"	"18"	"2"	"1745.0"	"1853.0"	"6228.8"	"1630.6"	"1472.0"	"1185.3"	"6751.8"	"824.3"	"1187.7"	"964.1"	"913.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01105"	"Protein SET OS=Homo sapiens OX=9606 GN=SET PE=1 SV=3"	"29"	"8"	"26"	"8"	"290"	"33.5"	"4.32"	"5112.98"	"53.86"	"7"	"7"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00956"	"6418"	"ENSG00000119335"	"SET"	"A5A5H4; A6NGV1; B4DUE2; hsa:6418; Q01105; Q15541; Q5VXV1; Q5VXV2; Q6FHZ5"	"HuR (ELAVL1) binds and stabilizes mRNA; Condensation of Prophase Chromosomes"	"Histone modifications; VEGFA-VEGFR2 signaling"	"4"	"0"	"1019.6"	"1338.2"	"4273.9"	"1152.1"	"1117.8"	"929.3"	"7126.5"	"1412.7"	"1826.8"	"1366.4"	"1283.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43684"	"Mitotic checkpoint protein BUB3 OS=Homo sapiens OX=9606 GN=BUB3 PE=1 SV=1"	"47"	"14"	"30"	"14"	"328"	"37.1"	"6.84"	"6513.69"	"53.36"	"13"	"12"	"cell cycle OR cell proliferation;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00400"	"9184"	"ENSG00000154473"	"BUB3"	"A6NJ42; B2R6E7; D3DRE9; hsa:9184; O43684; O43685"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of mitotic proteins; APC-Cdc20 mediated degradation of Nek2A"	"Cell cycle; Regulation of sister chromatid separation at the metaphase-anaphase transition"	"12"	"0"	"1461.9"	"1606.1"	"3222.0"	"1527.4"	"1492.0"	"1233.7"	"4082.8"	"1068.1"	"1726.2"	"1873.3"	"2790.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99613"	"Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1"	"18"	"16"	"31"	"16"	"913"	"105.3"	"5.68"	"5937.00"	"53.36"	"15"	"13"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf01399, Pf05470"	"8663"	"ENSG00000184110"	"EIF3C"	"A8K7Z0; B2RXG3; B4E1D5; H3BRV0; hsa:8663; O00215; Q99613; Q9BW98"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"8"	"0"	"1211.7"	"1181.6"	"3057.3"	"987.5"	"955.3"	"869.1"	"3257.6"	"571.8"	"801.9"	"681.5"	"721.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BUF5"	"Tubulin beta-6 chain OS=Homo sapiens OX=9606 GN=TUBB6 PE=1 SV=1"	"18"	"8"	"39"	"1"	"446"	"49.8"	"4.88"	"7158.62"	"53.19"	"8"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00091, Pf03953"	"84617"	"ENSG00000176014"	"TUBB6"	"B3KM76; hsa:84617; Q9BUF5; Q9HA42"	"Prefoldin mediated transfer of substrate  to CCT/TriC; Recycling pathway of L1; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; The role of GTSE1 in G2/M progression after G2 checkpoint; Intraflagellar transport; HCMV Early Events; Post-chaperonin tubulin folding pathway; COPI-dependent Golgi-to-ER retrograde traffic; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane; Gap junction assembly; MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Recruitment of NuMA to mitotic centrosomes; Formation of tubulin folding intermediates by CCT/TriC; RHO GTPases activate IQGAPs; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Carboxyterminal post-translational modifications of tubulin; Assembly and cell surface presentation of NMDA receptors; Activation of AMPK downstream of NMDARs; Aggrephagy; Sealing of the nuclear envelope (NE) by ESCRT-III; Kinesins; Hedgehog 'off' state"	"Alzheimer's disease and miRNA effects; Pathogenic Escherichia coli infection; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"34"	"0"	"49.8"	"45.5"	"158.5"	"43.1"	"55.0"	"31.5"	"179.2"	"32.7"	"54.4"	"56.6"	"60.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62195"	"26S proteasome regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMC5 PE=1 SV=1"	"46"	"16"	"29"	"14"	"406"	"45.6"	"7.55"	"4891.88"	"53.12"	"14"	"15"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00004, Pf16450, Pf17862"	"5705"	"ENSG00000087191"	"PSMC5"	"A8K3Z3; A8K763; hsa:5705; O35051; O43208; P47210; P52915; P52916; P62195"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Pregnane X receptor pathway; Nuclear receptors meta-pathway; Alzheimer's disease"	"65"	"1"	"1203.4"	"1171.4"	"3843.1"	"1070.0"	"914.2"	"774.2"	"3508.0"	"532.8"	"779.1"	"698.4"	"804.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P42704"	"Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3"	"14"	"18"	"35"	"18"	"1394"	"157.8"	"6.13"	"6655.50"	"52.74"	"18"	"15"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"other membranes;cytoskeleton;mitochondrion;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf01535"	"10128"	"ENSG00000138095"	"LRPPRC"	"A0PJE3; A8K1V1; hsa:10128; P42704; Q53PC0; Q53QN7; Q6ZUD8; Q7Z7A6; Q96D84"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"Ciliary landscape"	"4"	"0"	"1482.8"	"1888.6"	"7570.4"	"1783.2"	"1532.5"	"1259.3"	"7171.8"	"734.3"	"1112.3"	"885.8"	"860.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P32119"	"Peroxiredoxin-2 OS=Homo sapiens OX=9606 GN=PRDX2 PE=1 SV=5"	"35"	"10"	"35"	"9"	"198"	"21.9"	"5.97"	"6711.98"	"52.60"	"9"	"10"	"cell cycle OR cell proliferation;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00578, Pf10417"	"7001"	"ENSG00000167815"	"PRDX2"	"A8K0C0; hsa:7001; P31945; P32118; P32119; P35701; Q6FHG4; Q92763; Q9UC23"	"TP53 Regulates Metabolic Genes; Detoxification of Reactive Oxygen Species; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"	"Selenium micronutrient network; VEGFA-VEGFR2 signaling"	"5"	"0"	"976.0"	"999.8"	"4045.9"	"934.0"	"804.3"	"673.0"	"5287.0"	"592.3"	"784.0"	"543.3"	"502.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62424"	"60S ribosomal protein L7a OS=Homo sapiens OX=9606 GN=RPL7A PE=1 SV=2"	"53"	"17"	"33"	"17"	"266"	"30.0"	"10.61"	"7076.26"	"52.25"	"15"	"13"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01248"	"6130"	"ENSG00000148303; ENSG00000280858"	"RPL7A"	"hsa:6130; P11518; P62424; Q5T8U4"	"L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"2551.1"	"2734.8"	"8165.9"	"2423.3"	"2356.7"	"1965.6"	"11058.6"	"1058.1"	"1685.7"	"1132.0"	"1028.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46782"	"40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4"	"44"	"11"	"30"	"11"	"204"	"22.9"	"9.72"	"6041.10"	"52.00"	"11"	"10"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00177"	"6193"	"ENSG00000083845"	"RPS5"	"B2R4T2; hsa:6193; P46782; Q96BN0"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"1185.8"	"1134.2"	"3072.6"	"911.5"	"893.9"	"753.2"	"3867.8"	"550.0"	"695.4"	"553.1"	"539.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95757"	"Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3"	"21"	"14"	"28"	"11"	"839"	"94.5"	"5.88"	"4625.62"	"51.92"	"11"	"13"	"stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00012"	"22824"	"ENSG00000164070"	"HSPA4L"	"A2ICT2; hsa:22824; O95757; Q4W5M5; Q8IWA2"	"Regulation of HSF1-mediated heat shock response"	""	"1"	"2"	"894.9"	"1122.0"	"3512.0"	"1113.8"	"997.4"	"893.6"	"4326.2"	"617.2"	"888.7"	"697.5"	"723.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P21333"	"Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4"	"8"	"18"	"31"	"15"	"2647"	"280.6"	"6.06"	"6095.61"	"51.90"	"16"	"15"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00307, Pf00630"	"2316"	"ENSG00000196924"	"FLNA"	"E9KL45; hsa:2316; P21333; Q5HY53; Q5HY55; Q8NF52"	"OAS antiviral response; Platelet degranulation ; RHO GTPases activate PAKs; GP1b-IX-V activation signalling; Cell-extracellular matrix interactions"	"Androgen receptor signaling pathway; Prolactin signaling pathway; Focal adhesion; Hypothesized pathways in pathogenesis of cardiovascular disease; MAPK signaling pathway; IL-4 signaling pathway; Ebola virus infection in host; Joubert syndrome"	"13"	"0"	"1384.5"	"1542.6"	"6761.0"	"1387.0"	"948.7"	"762.3"	"5486.6"	"543.3"	"892.2"	"635.1"	"630.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55884"	"Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3"	"22"	"14"	"26"	"14"	"814"	"92.4"	"5.00"	"4217.60"	"51.68"	"11"	"13"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08662"	"8662"	"ENSG00000106263"	"EIF3B"	"A4D208; hsa:8662; P55884; Q2NL77; Q9UMF9"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"8"	"0"	"786.1"	"780.4"	"2696.8"	"797.7"	"691.3"	"523.4"	"2818.4"	"345.9"	"525.0"	"436.0"	"424.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00159"	"Unconventional myosin-Ic OS=Homo sapiens OX=9606 GN=MYO1C PE=1 SV=4"	"12"	"11"	"25"	"10"	"1063"	"121.6"	"9.41"	"4332.08"	"51.63"	"9"	"11"	"cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00063, Pf00612, Pf06017"	"4641"	"ENSG00000197879"	"MYO1C"	"hsa:4641; O00159; Q4LE56; Q6NVJ7; Q86Y95"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Translocation of SLC2A4 (GLUT4) to the plasma membrane"	"VEGFA-VEGFR2 signaling; Insulin signaling"	"7"	"1"	"158.2"	"149.6"	"495.5"	"153.6"	"173.6"	"127.1"	"544.7"	"273.3"	"1033.7"	"1311.8"	"1627.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23921"	"Ribonucleoside-diphosphate reductase large subunit OS=Homo sapiens OX=9606 GN=RRM1 PE=1 SV=1"	"21"	"12"	"22"	"12"	"792"	"90.0"	"7.15"	"3885.36"	"51.49"	"9"	"11"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf00317, Pf02867, Pf03477"	"6240"	"ENSG00000167325"	"RRM1"	"hsa:6240; P23921; Q9UNN2"	"Interconversion of nucleotide di- and triphosphates"	"Fluoropyrimidine activity; Retinoblastoma gene in cancer; Pyrimidine metabolism"	"4"	"0"	"526.6"	"653.1"	"1766.8"	"730.0"	"740.3"	"686.3"	"2233.4"	"469.2"	"939.5"	"938.6"	"1316.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95831"	"Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1"	"24"	"12"	"30"	"12"	"613"	"66.9"	"8.95"	"5804.84"	"50.74"	"11"	"11"	"cell organization and biogenesis;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00070, Pf14721"	"9131"	"ENSG00000156709"	"AIFM1"	"A4QPB4; B1ALN1; B2RB08; D3DTE9; E9PRR0; hsa:9131; O95831; Q1L6K4; Q1L6K6; Q2QKE4; Q5JUZ7; Q6I9X6; Q9Y3I3; Q9Y3I4"	""	"Apoptosis modulation and signaling; Nanomaterial induced apoptosis; Apoptosis modulation by HSP70"	"3"	"0"	"872.8"	"1225.2"	"3161.5"	"1298.7"	"1186.0"	"1031.6"	"4362.1"	"897.9"	"1296.9"	"1046.0"	"1068.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13667"	"Protein disulfide-isomerase A4 OS=Homo sapiens OX=9606 GN=PDIA4 PE=1 SV=2"	"32"	"21"	"36"	"21"	"645"	"72.9"	"5.07"	"6648.38"	"50.73"	"19"	"15"	"stress response;transport;other biological processes"	"non-structural extracellular;ER/Golgi;other cell component"	"other molecular function"	"Pf00085, Pf13848"	"9601"	"ENSG00000155660"	"PDIA4"	"A8K4K6; hsa:9601; P13667; Q549T6"	""	""	"0"	"0"	"1838.6"	"1897.0"	"7135.9"	"2024.8"	"1416.0"	"1012.2"	"5919.1"	"777.2"	"1066.1"	"1115.7"	"990.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q07020"	"60S ribosomal protein L18 OS=Homo sapiens OX=9606 GN=RPL18 PE=1 SV=2"	"51"	"12"	"27"	"12"	"188"	"21.6"	"11.72"	"5019.02"	"50.67"	"11"	"11"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf17135"	"6141"	"ENSG00000063177"	"RPL18"	"F8VWC5; hsa:6141; Q07020; Q8WTZ6"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"1907.0"	"2059.1"	"5867.9"	"1913.1"	"1864.1"	"1641.4"	"5400.9"	"748.7"	"1037.6"	"717.7"	"648.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00232"	"26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3"	"35"	"15"	"32"	"15"	"456"	"52.9"	"7.65"	"5310.20"	"50.62"	"12"	"14"	"protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	""	"Pf01399, Pf18098"	"5718"	"ENSG00000197170"	"PSMD12"	"A6NP15; hsa:5718; O00232; Q53HA2; Q6P053"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Ciliary landscape; Alzheimer's disease"	"65"	"0"	"1714.1"	"1799.4"	"6303.7"	"1758.8"	"1330.6"	"1129.6"	"4803.6"	"539.6"	"764.1"	"775.0"	"820.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62826"	"GTP-binding nuclear protein Ran OS=Homo sapiens OX=9606 GN=RAN PE=1 SV=3"	"49"	"8"	"20"	"8"	"216"	"24.4"	"7.49"	"2624.48"	"50.57"	"5"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00071"	"5901"	"ENSG00000132341"	"RAN"	"A8K3Z8; hsa:5901; P17080; P28746; P28747; P62826; Q6IPB2; Q86V08; Q8NI90; Q9CSP3; Q9CWI7; Q9CZA2; Q9UDJ5; Q9UEU9"	"Transcriptional regulation by small RNAs; Rev-mediated nuclear export of HIV RNA; NEP/NS2 Interacts with the Cellular Export Machinery; Nuclear import of Rev protein; tRNA processing in the nucleus; Regulation of cholesterol biosynthesis by SREBP (SREBF); MicroRNA (miRNA) biogenesis; Postmitotic nuclear pore complex (NPC) reformation"	"Androgen receptor signaling pathway; miRNA biogenesis; 22q11.2 copy number variation syndrome"	"11"	"0"	"617.0"	"764.1"	"2588.8"	"761.0"	"689.6"	"500.7"	"3927.2"	"529.1"	"628.5"	"463.2"	"476.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15365"	"Poly(rC)-binding protein 1 OS=Homo sapiens OX=9606 GN=PCBP1 PE=1 SV=2"	"34"	"10"	"23"	"5"	"356"	"37.5"	"7.09"	"4170.19"	"50.27"	"8"	"10"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013"	"5093"	"ENSG00000169564"	"PCBP1"	"hsa:5093; Q13157; Q14975; Q15365"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"Ferroptosis"	"3"	"7"	"798.7"	"1171.9"	"3775.6"	"980.6"	"956.1"	"799.6"	"4177.9"	"551.6"	"733.3"	"593.9"	"664.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92598"	"Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1"	"21"	"14"	"28"	"12"	"858"	"96.8"	"5.39"	"5020.52"	"49.95"	"12"	"12"	"stress response;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00012"	"10808"	"ENSG00000120694"	"HSPH1"	"B4DYH1; hsa:10808; O95739; Q5TBM6; Q5TBM7; Q5TBM8; Q92598; Q9UPC4"	"Regulation of HSF1-mediated heat shock response; Scavenging by Class F Receptors"	""	"2"	"0"	"905.8"	"1126.3"	"4003.0"	"1145.8"	"1000.8"	"812.7"	"4793.4"	"599.2"	"987.8"	"834.3"	"803.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P16152"	"Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3"	"48"	"11"	"26"	"11"	"277"	"30.4"	"8.32"	"4807.37"	"49.87"	"10"	"11"	"other metabolic processes;other biological processes"	"cytosol"	"other molecular function"	"Pf00106"	"873"	"ENSG00000159228"	"CBR1"	"B2RBZ7; B4DFK7; hsa:873; P16152; Q3LHW8"	"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)"	"Nuclear receptors meta-pathway; NRF2 pathway; Prostaglandin synthesis and regulation"	"4"	"0"	"751.1"	"876.3"	"2994.6"	"1093.3"	"990.0"	"871.6"	"4341.6"	"756.1"	"1238.3"	"1073.5"	"1574.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NC51"	"Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2"	"35"	"15"	"29"	"15"	"408"	"44.9"	"8.65"	"6736.33"	"49.79"	"14"	"12"	"cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf04774, Pf16174"	"26135"	"ENSG00000142864"	"SERBP1"	"hsa:26135; Q5VU19; Q5VU20; Q5VU22; Q8NC51; Q8WUH0; Q96SE2; Q9BTY3; Q9BUM4; Q9Y367; Q9Y4S3"	""	"Apoptosis-related network due to altered Notch3 in ovarian cancer"	"1"	"0"	"2118.6"	"2119.8"	"5857.4"	"1979.4"	"1885.7"	"1617.5"	"7191.8"	"1060.4"	"1828.6"	"1281.5"	"1311.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3F4"	"Serine-threonine kinase receptor-associated protein OS=Homo sapiens OX=9606 GN=STRAP PE=1 SV=1"	"34"	"9"	"26"	"9"	"350"	"38.4"	"5.12"	"5845.90"	"49.62"	"9"	"8"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00400"	"11171"	"ENSG00000023734"	"STRAP"	"B2R5S5; B4DNJ6; hsa:11171; Q5TZT4; Q9NTK0; Q9UQC8; Q9Y3F4"	"Downregulation of TGF-beta receptor signaling"	"Epithelial to mesenchymal transition in colorectal cancer"	"2"	"0"	"882.2"	"1248.5"	"4531.4"	"1353.4"	"1283.2"	"1224.3"	"5246.1"	"690.0"	"1245.9"	"787.4"	"829.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y490"	"Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3"	"8"	"17"	"29"	"17"	"2541"	"269.6"	"6.07"	"5412.11"	"49.49"	"15"	"14"	"cell adhesion;cell organization and biogenesis;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00373, Pf01608, Pf08913, Pf09141, Pf16511"	"7094"	"ENSG00000137076"	"TLN1"	"A6NMY0; hsa:7094; Q86YD0; Q9NZQ2; Q9UHH8; Q9UPX3; Q9Y490"	"Platelet degranulation ; Signaling by BRAF and RAF1 fusions; XBP1(S) activates chaperone genes; SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion; Smooth Muscle Contraction; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; GRB2:SOS provides linkage to MAPK signaling for Integrins ; p130Cas linkage to MAPK signaling for integrins"	"Integrin-mediated cell adhesion; Primary focal segmental glomerulosclerosis (FSGS); Focal adhesion; TROP2 regulatory signaling"	"18"	"0"	"798.7"	"944.2"	"3497.1"	"856.8"	"744.3"	"584.7"	"3067.7"	"353.4"	"553.1"	"585.5"	"667.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22061"	"Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens OX=9606 GN=PCMT1 PE=1 SV=4"	"42"	"9"	"30"	"9"	"227"	"24.6"	"7.21"	"7306.04"	"49.16"	"9"	"8"	"protein metabolism;other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf01135"	"5110"	"ENSG00000120265"	"PCMT1"	"A8K109; hsa:5110; J3KP72; P22061; Q14661; Q16556; Q5VYC1; Q5VYC2; Q93061; Q96II9; Q99625; Q9BQV7; Q9BQV8; Q9NP03"	"Protein repair"	"Primary ovarian insufficiency"	"2"	"0"	"978.2"	"1864.0"	"3722.9"	"1684.4"	"1812.2"	"1914.6"	"4491.2"	"1349.4"	"1889.9"	"1231.3"	"1290.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P17844"	"Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1"	"27"	"15"	"28"	"10"	"614"	"69.1"	"8.92"	"5133.37"	"49.16"	"12"	"14"	"RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf08061"	"1655"	"ENSG00000108654"	"DDX5"	"B4DLW8; B5BU21; D3DU32; E7ETL9; hsa:1655; O75681; P17844; Q53Y61"	"mRNA Splicing - Major Pathway; SUMOylation of transcription cofactors; Estrogen-dependent gene expression; Replication of the SARS-CoV-1 genome; Replication of the SARS-CoV-2 genome"	"Ciliary landscape"	"6"	"0"	"1184.3"	"1228.9"	"3588.9"	"1085.4"	"1067.5"	"884.5"	"4012.2"	"451.0"	"723.6"	"526.5"	"547.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16775"	"Hydroxyacylglutathione hydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=HAGH PE=1 SV=2"	"39"	"8"	"23"	"8"	"308"	"33.8"	"8.12"	"4119.72"	"49.10"	"6"	"8"	"other metabolic processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00753, Pf16123"	"3029"	"ENSG00000063854"	"HAGH"	"A8K290; B4DP33; B4DRA7; E7EN93; hsa:3029; Q16775"	""	""	"0"	"0"	"426.1"	"476.7"	"862.7"	"462.3"	"499.4"	"515.6"	"1241.8"	"533.9"	"699.8"	"590.7"	"600.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15084"	"Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1"	"25"	"10"	"23"	"10"	"440"	"48.1"	"5.08"	"4225.84"	"49.07"	"8"	"10"	"stress response;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00085"	"10130"	"ENSG00000143870"	"PDIA6"	"B3KY95; B5MCQ5; B7Z254; B7Z4M8; F8WA83; hsa:10130; Q15084; Q53RC7; Q6ZSH5; Q99778"	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; XBP1(S) activates chaperone genes"	"Photodynamic therapy-induced unfolded protein response; VEGFA-VEGFR2 signaling"	"5"	"0"	"811.6"	"866.7"	"2141.4"	"868.2"	"713.8"	"731.2"	"2912.5"	"576.4"	"736.5"	"581.4"	"725.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y617"	"Phosphoserine aminotransferase OS=Homo sapiens OX=9606 GN=PSAT1 PE=1 SV=2"	"41"	"14"	"29"	"14"	"370"	"40.4"	"7.66"	"5041.30"	"48.97"	"12"	"11"	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00266"	"29968"	"ENSG00000135069"	"PSAT1"	"hsa:29968; Q5T7G5; Q5T7G6; Q96AW2; Q9BQ12; Q9Y617"	"Serine biosynthesis"	"Trans-sulfuration, one-carbon metabolism and related pathways; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Male infertility; Neuroinflammation and glutamatergic signaling; Amino acid metabolism in triple-negative breast cancer cells"	"7"	"0"	"968.0"	"1351.0"	"6633.3"	"1199.9"	"1029.3"	"698.8"	"8784.2"	"789.0"	"864.6"	"702.7"	"598.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31946"	"14-3-3 protein beta/alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3"	"45"	"12"	"33"	"5"	"246"	"28.1"	"4.83"	"6719.93"	"48.26"	"12"	"9"	"transport;signal transduction;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00244"	"7529"	"ENSG00000166913"	"YWHAB"	"A8K9K2; E1P616; hsa:7529; P31946"	"TP53 Regulates Metabolic Genes; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by BRAF and RAF1 fusions; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Regulation of localization of FOXO transcription factors; mTORC1-mediated signalling; Signaling by Hippo; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RAF activation; SHOC2 M1731 mutant abolishes MRAS complex function; Gain-of-function MRAS complexes activate RAF signaling; RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Rap1 signalling; Negative regulation of MAPK pathway; Frs2-mediated activation; ARMS-mediated activation; Activation of BAD and translocation to mitochondria ; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"	"Cell cycle; IL-3 signaling pathway; Myometrial relaxation and contraction pathways; Hepatitis B infection; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"33"	"4"	"631.7"	"1043.5"	"3247.4"	"982.0"	"884.9"	"854.3"	"4398.5"	"760.0"	"1113.3"	"875.8"	"926.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62906"	"60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2"	"47"	"12"	"29"	"12"	"217"	"24.8"	"9.94"	"7311.27"	"48.01"	"12"	"11"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf00687"	"4736"	"ENSG00000198755"	"RPL10A"	"B2R801; hsa:4736; P52859; P53025; P62906; Q5TZT6; Q8J013"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"15"	"0"	"2010.9"	"2143.9"	"6386.4"	"1876.9"	"1661.9"	"1427.7"	"7279.7"	"665.3"	"1013.0"	"667.0"	"655.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63244"	"Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3"	"38"	"14"	"31"	"14"	"317"	"35.1"	"7.69"	"5997.54"	"47.66"	"14"	"13"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;cytosol;mitochondrion;translational apparatus;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;translation activity;other molecular function"	"Pf00400"	"10399"	"ENSG00000204628"	"RACK1"	"B3KTJ0; D3DWS0; hsa:10399; P25388; P63244; P99049; Q53HU2; Q5J8M6; Q5VLR4; Q6FH47"	"Regulation of TNFR1 signaling; TNFR1-induced NF-kappa-B signaling pathway; TNFR1-mediated ceramide production"	"Androgen receptor signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; VEGFA-VEGFR2 signaling; Measles virus infection; Angiotensin II receptor type 1 pathway; TROP2 regulatory signaling; Interferon type I signaling pathways"	"10"	"0"	"2198.9"	"2225.2"	"7486.7"	"1927.5"	"1838.0"	"1598.1"	"6189.3"	"453.8"	"885.9"	"655.6"	"670.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NZI8"	"Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2"	"21"	"11"	"25"	"10"	"577"	"63.4"	"9.20"	"5278.07"	"47.44"	"11"	"11"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf00076"	"10642"	"ENSG00000159217"	"IGF2BP1"	"C9JT33; hsa:10642; Q9NZI8"	"MAPK6/MAPK4 signaling; Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; eIF5A regulation in response to inhibition of the nuclear export system"	"4"	"2"	"1680.6"	"1734.5"	"5812.1"	"1550.4"	"1454.9"	"1168.7"	"6037.9"	"637.3"	"1028.9"	"759.9"	"826.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46109"	"Crk-like protein OS=Homo sapiens OX=9606 GN=CRKL PE=1 SV=1"	"44"	"11"	"25"	"11"	"303"	"33.8"	"6.74"	"4962.52"	"47.29"	"10"	"10"	"cell-cell signaling;cell organization and biogenesis;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00017, Pf00018, Pf07653"	"1399"	"ENSG00000099942"	"CRKL"	"A8KA44; D3DX35; hsa:1399; P46109"	"Frs2-mediated activation; Regulation of signaling by CBL; Downstream signal transduction; Erythropoietin activates RAS; MET activates RAP1 and RAC1; MET receptor recycling"	"Androgen receptor network in prostate cancer; B cell receptor signaling pathway; IL-3 signaling pathway; Kit receptor signaling pathway; Focal adhesion; Hepatocyte growth factor receptor signaling; MAPK signaling pathway; Chemokine signaling pathway; EGF/EGFR signaling pathway; 22q11.2 copy number variation syndrome; IL-2 signaling pathway; A network map of Macrophage-stimulating protein (MSP) signaling; Interferon type I signaling pathways; ErbB signaling pathway; T-cell receptor signaling pathway"	"21"	"0"	"1098.7"	"1081.8"	"2304.2"	"1022.6"	"1073.8"	"1070.6"	"2385.2"	"584.4"	"869.4"	"678.0"	"766.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P54819"	"Adenylate kinase 2, mitochondrial OS=Homo sapiens OX=9606 GN=AK2 PE=1 SV=2"	"63"	"12"	"22"	"12"	"239"	"26.5"	"7.81"	"4380.91"	"47.17"	"10"	"11"	"other metabolic processes"	"cytoskeleton;mitochondrion;other cell component"	"kinase activity;other molecular function"	"Pf00406, Pf05191"	"204"	"ENSG00000004455"	"AK2"	"A8K6L1; B4DHH7; B4DL64; hsa:204; P54819; Q16856; Q5EB54; Q5TIF7; Q8TCY2; Q8TCY3"	"Interconversion of nucleotide di- and triphosphates"	""	"1"	"0"	"389.8"	"540.2"	"2258.3"	"525.7"	"551.4"	"438.8"	"3726.5"	"337.6"	"505.9"	"360.2"	"331.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08708"	"40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2"	"64"	"9"	"17"	"9"	"135"	"15.5"	"9.85"	"2122.08"	"47.14"	"5"	"9"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00833"	"6218"	"ENSG00000182774; ENSG00000278229"	"RPS17"	"B2R4U4; hsa:6218; P08708; P0CW22"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"855.4"	"915.8"	"2359.4"	"805.1"	"790.1"	"636.7"	"2766.8"	"396.3"	"579.8"	"451.9"	"403.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00231"	"26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3"	"37"	"12"	"25"	"12"	"422"	"47.4"	"6.48"	"5145.59"	"46.55"	"11"	"12"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf01399, Pf18055, Pf18503"	"5717"	"ENSG00000108671"	"PSMD11"	"A8K3I7; E1P663; hsa:5717; O00231; O00495; Q53FT5"	"Separation of Sister Chromatids; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Parkin-ubiquitin proteasomal system pathway; VEGFA-VEGFR2 signaling"	"63"	"0"	"987.1"	"1067.3"	"3159.6"	"882.1"	"781.1"	"683.0"	"2473.1"	"372.5"	"568.7"	"512.6"	"560.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50395"	"Rab GDP dissociation inhibitor beta OS=Homo sapiens OX=9606 GN=GDI2 PE=1 SV=2"	"36"	"13"	"26"	"8"	"445"	"50.6"	"6.47"	"5906.06"	"46.54"	"11"	"11"	"transport;signal transduction;other biological processes"	"non-structural extracellular;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00996"	"2665"	"ENSG00000057608"	"GDI2"	"hsa:2665; O43928; P50395; Q5SX88; Q9UQM6"	"Neutrophil degranulation; RAB GEFs exchange GTP for GDP on RABs"	""	"2"	"4"	"699.8"	"793.0"	"3228.4"	"838.2"	"767.8"	"544.0"	"4607.9"	"442.9"	"694.4"	"588.5"	"561.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P26639"	"Threonine--tRNA ligase 1, cytoplasmic OS=Homo sapiens OX=9606 GN=TARS1 PE=1 SV=3"	"21"	"12"	"25"	"12"	"723"	"83.4"	"6.67"	"3976.18"	"46.20"	"10"	"11"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol"	"nucleic acid binding activity;other molecular function"	"Pf00587, Pf02824, Pf03129, Pf07973"	"6897"	"ENSG00000113407"	"TARS1"	"A8K8I1; B4DEG8; hsa:6897; P26639; Q96FP5; Q9BWA6"	"Cytosolic tRNA aminoacylation"	""	"1"	"0"	"494.9"	"527.9"	"2405.1"	"487.4"	"340.3"	"335.7"	"2481.3"	"451.2"	"750.9"	"1346.8"	"3780.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P27824"	"Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2"	"26"	"16"	"26"	"16"	"592"	"67.5"	"4.60"	"5355.96"	"45.69"	"13"	"13"	"protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;translational apparatus;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00262"	"821"	"ENSG00000127022; ENSG00000283777"	"CANX"	"B2R5V8; B4DGP8; B4E2T8; D3DWQ3; D6R9K3; hsa:821; P27824"	"Maturation of spike protein; MHC class II antigen presentation; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Interleukin-35 Signalling; Interleukin-27 signaling; Assembly of Viral Components at the Budding Site; Calnexin/calreticulin cycle; Maturation of spike protein"	""	"8"	"0"	"1814.5"	"1805.1"	"8640.7"	"1791.1"	"1683.6"	"1048.7"	"9519.0"	"624.8"	"1233.4"	"752.1"	"745.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P39019"	"40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2"	"46"	"10"	"29"	"10"	"145"	"16.1"	"10.32"	"6037.31"	"45.67"	"10"	"10"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01090"	"6223"	"ENSG00000105372"	"RPS19"	"hsa:6223; P39019"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Complement system; Cytoplasmic ribosomal proteins"	"20"	"0"	"1708.8"	"1759.1"	"4750.9"	"1493.0"	"1603.4"	"1393.5"	"6976.2"	"744.9"	"1119.9"	"861.0"	"886.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3I0"	"RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1"	"27"	"13"	"25"	"13"	"505"	"55.2"	"7.23"	"4000.02"	"45.65"	"11"	"12"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01139"	"51493"	"ENSG00000100220"	"RTCB"	"B2R6A8; hsa:51493; Q6IAI0; Q9BWL4; Q9NTH1; Q9P037; Q9P0J3; Q9Y3I0"	"tRNA processing in the nucleus"	"Unfolded protein response"	"2"	"0"	"1583.0"	"1814.8"	"4270.5"	"1570.9"	"1355.8"	"1233.2"	"4304.4"	"883.8"	"1213.0"	"1019.4"	"1114.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99623"	"Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2"	"46"	"13"	"31"	"13"	"299"	"33.3"	"9.83"	"7230.02"	"45.59"	"13"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01145"	"11331"	"ENSG00000215021"	"PHB2"	"B4DP75; hsa:11331; Q2YDA4; Q7KYU3; Q92978; Q99623"	"Processing of SMDT1"	""	"1"	"0"	"1518.8"	"1721.0"	"6623.1"	"1376.9"	"1122.1"	"890.2"	"4502.3"	"467.5"	"957.0"	"649.3"	"690.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60869"	"Endothelial differentiation-related factor 1 OS=Homo sapiens OX=9606 GN=EDF1 PE=1 SV=1"	"64"	"13"	"28"	"13"	"148"	"16.4"	"9.95"	"5638.73"	"45.20"	"13"	"9"	"RNA metabolism OR transcription;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01381, Pf08523"	"8721"	"ENSG00000107223"	"EDF1"	"hsa:8721; O60869; Q5T5T2; Q9UIM1"	""	""	"0"	"0"	"1104.1"	"1013.3"	"2210.2"	"962.5"	"955.6"	"762.8"	"6732.6"	"1996.9"	"3264.1"	"2779.4"	"2941.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61604"	"10 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPE1 PE=1 SV=2"	"86"	"15"	"31"	"15"	"102"	"10.9"	"8.92"	"6261.82"	"45.19"	"14"	"12"	"stress response;other biological processes"	"mitochondrion"	"other molecular function"	"Pf00166"	"3336"	"ENSG00000115541"	"HSPE1"	"hsa:3336; O95421; P61604; Q04984; Q53X54; Q9UDH0"	"RHOG GTPase cycle"	""	"1"	"0"	"2493.6"	"3300.4"	"14212.1"	"2908.4"	"2460.0"	"1904.5"	"10782.3"	"1199.7"	"1730.2"	"1502.4"	"1923.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q04917"	"14-3-3 protein eta OS=Homo sapiens OX=9606 GN=YWHAH PE=1 SV=4"	"31"	"8"	"24"	"4"	"246"	"28.2"	"4.84"	"3829.44"	"44.87"	"7"	"8"	"other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00244"	"7533"	"ENSG00000128245"	"YWHAH"	"hsa:7533; Q04917"	"TP53 Regulates Metabolic Genes; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RHO GTPases activate PKNs; Translocation of SLC2A4 (GLUT4) to the plasma membrane; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Activation of BAD and translocation to mitochondria"	"Cell cycle; Myometrial relaxation and contraction pathways; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"11"	"0"	"562.4"	"756.8"	"2244.6"	"675.0"	"653.8"	"661.6"	"2523.3"	"568.5"	"795.0"	"698.3"	"757.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06454"	"Prothymosin alpha OS=Homo sapiens OX=9606 GN=PTMA PE=1 SV=2"	"23"	"5"	"26"	"5"	"111"	"12.2"	"3.78"	"5745.82"	"44.74"	"5"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf03247"	"5757"	"ENSG00000187514"	"PTMA"	"hsa:5757; P06454; Q15249; Q15592"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"371.4"	"376.2"	"1503.8"	"398.9"	"397.2"	"310.5"	"1887.3"	"216.3"	"301.9"	"209.1"	"140.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q58FF6"	"Putative heat shock protein HSP 90-beta 4 OS=Homo sapiens OX=9606 GN=HSP90AB4P PE=5 SV=1"	"10"	"7"	"26"	"1"	"505"	"58.2"	"4.73"	"5878.64"	"44.15"	"7"	"5"	"stress response;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00183, Pf02518"	""	""	"HSP90AB4P"	"Q58FF6"	""	""	"0"	"0"	"33.5"	"32.6"	"260.5"	"22.0"	"18.8"	"12.8"	"244.5"	"10.7"	"9.2"	"7.7"	"11.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55209"	"Nucleosome assembly protein 1-like 1 OS=Homo sapiens OX=9606 GN=NAP1L1 PE=1 SV=1"	"36"	"11"	"25"	"9"	"391"	"45.3"	"4.46"	"4254.22"	"43.99"	"9"	"10"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00956"	"4673"	"ENSG00000187109"	"NAP1L1"	"B3KNT8; B3KV44; hsa:4673; P55209"	""	"VEGFA-VEGFR2 signaling; Overlap between signal transduction pathways contributing to LMNA laminopathies"	"2"	"2"	"761.9"	"733.9"	"2836.5"	"898.5"	"700.2"	"606.2"	"3605.7"	"390.8"	"622.3"	"475.1"	"427.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P78347"	"General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2"	"14"	"12"	"27"	"12"	"998"	"112.3"	"6.39"	"6640.44"	"43.98"	"11"	"8"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02946"	"2969"	"ENSG00000263001"	"GTF2I"	"hsa:2969; O14743; O15359; O43546; O43588; O43589; P78347; Q75M85; Q75M86; Q75M87; Q75M88; Q86U51; Q9BSZ4"	""	"B cell receptor signaling pathway; 7q11.23 copy number variation syndrome; Genetic causes of porto-sinusoidal vascular disease"	"3"	"0"	"781.9"	"917.6"	"3605.8"	"952.7"	"875.1"	"675.8"	"4246.4"	"492.1"	"802.8"	"696.4"	"666.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05023"	"Sodium/potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1"	"14"	"13"	"25"	"13"	"1023"	"112.8"	"5.49"	"4381.61"	"43.77"	"12"	"12"	"transport;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;other cell component"	"transporter activity;other molecular function"	"Pf00122, Pf00689, Pf00690, Pf13246"	"476"	"ENSG00000163399"	"ATP1A1"	"B2RBR6; B7Z2T5; B7Z3U6; F5H3A1; hsa:476; P05023; Q16689; Q6LDM4; Q9UCN1; Q9UJ20; Q9UJ21"	"Potential therapeutics for SARS; Ion homeostasis; Ion transport by P-type ATPases"	"Pre-implantation embryo; Proximal tubule transport; Arsenic metabolism and reactive oxygen species generation"	"6"	"0"	"1453.9"	"1525.0"	"5496.1"	"1352.0"	"1177.5"	"914.0"	"5350.5"	"592.5"	"941.6"	"764.0"	"771.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y230"	"RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3"	"40"	"14"	"26"	"14"	"463"	"51.1"	"5.64"	"4458.23"	"43.69"	"12"	"14"	"cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06068, Pf17856"	"10856"	"ENSG00000183207"	"RUVBL2"	"B3KQ59; E7ETE5; hsa:10856; Q6FIB9; Q6PK27; Q9Y230; Q9Y361"	"HATs acetylate histones; Telomere Extension By Telomerase"	""	"2"	"0"	"791.0"	"778.5"	"3120.0"	"718.7"	"648.7"	"457.4"	"3575.6"	"352.4"	"483.9"	"395.8"	"407.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22392"	"Nucleoside diphosphate kinase B OS=Homo sapiens OX=9606 GN=NME2 PE=1 SV=1"	"51"	"7"	"27"	"3"	"152"	"17.3"	"8.41"	"4848.11"	"43.56"	"6"	"7"	"cell adhesion;protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00334"	"4831; 654364"	"ENSG00000243678"	"NME2"	"A8MWA3; hsa:4831; hsa:654364; P22392; Q1WM23; Q6LCT6"	"Neutrophil degranulation; Interconversion of nucleotide di- and triphosphates; Azathioprine ADME; Ribavirin ADME"	"Pyrimidine metabolism"	"5"	"0"	"498.1"	"570.0"	"2294.7"	"474.3"	"361.0"	"218.2"	"2319.8"	"250.3"	"234.2"	"215.0"	"209.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07195"	"L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2"	"35"	"13"	"27"	"12"	"334"	"36.6"	"6.05"	"6118.09"	"43.46"	"13"	"10"	"other metabolic processes"	"other membranes;cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00056, Pf02866"	"3945"	"ENSG00000111716"	"LDHB"	"hsa:3945; P07195"	"Pyruvate metabolism"	"Clear cell renal cell carcinoma pathways; CCL18 signaling pathway; Glycolysis and gluconeogenesis"	"4"	"1"	"1382.3"	"1604.4"	"7122.4"	"1282.2"	"1283.9"	"832.0"	"9218.3"	"732.5"	"938.4"	"661.5"	"467.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52209"	"6-phosphogluconate dehydrogenase, decarboxylating OS=Homo sapiens OX=9606 GN=PGD PE=1 SV=3"	"35"	"14"	"24"	"14"	"483"	"53.1"	"7.23"	"4191.15"	"43.43"	"11"	"11"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf00393, Pf03446"	"5226"	"ENSG00000142657"	"PGD"	"A8K2Y9; B4DQJ8; hsa:5226; P52209; Q9BWD8"	"NFE2L2 regulates pentose phosphate pathway genes; Pentose phosphate pathway"	"Pentose phosphate metabolism; Nuclear receptors meta-pathway; NRF2 pathway; VEGFA-VEGFR2 signaling; Metabolic reprogramming in colon cancer"	"7"	"0"	"1262.0"	"1688.1"	"4150.2"	"2047.9"	"1767.6"	"1501.7"	"4052.4"	"675.6"	"1209.0"	"1137.2"	"1985.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P12532"	"Creatine kinase U-type, mitochondrial OS=Homo sapiens OX=9606 GN=CKMT1A PE=1 SV=1"	"20"	"10"	"27"	"10"	"417"	"47.0"	"8.34"	"4967.98"	"43.28"	"10"	"9"	"other metabolic processes"	"other membranes;mitochondrion"	"kinase activity;other molecular function"	"Pf00217, Pf02807"	"1159; 548596"	"ENSG00000223572; ENSG00000237289"	"CKMT1A; CKMT1B"	"B4DIT8; B7ZA09; hsa:1159; hsa:548596; P12532; Q0VAM3; Q32NF6; Q53FC4"	"Creatine metabolism"	""	"1"	"0"	"1561.8"	"1746.1"	"3721.9"	"1690.3"	"1607.2"	"1483.7"	"3309.9"	"645.3"	"938.8"	"760.9"	"696.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P54886"	"Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2"	"25"	"15"	"27"	"15"	"795"	"87.2"	"7.12"	"4259.96"	"43.28"	"13"	"14"	"other metabolic processes"	"other membranes;mitochondrion"	"kinase activity;other molecular function"	"Pf00171, Pf00696"	"5832"	"ENSG00000059573"	"ALDH18A1"	"B2R5Q4; B7Z350; B7Z5X8; B7ZLP1; D3DR44; hsa:5832; O95952; P54886; Q3KQU2; Q5T566; Q5T567; Q9UM72"	""	"Amino acid metabolism"	"1"	"0"	"615.8"	"840.9"	"2979.9"	"801.0"	"741.4"	"592.1"	"2925.2"	"363.7"	"528.8"	"427.6"	"394.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P33992"	"DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5"	"19"	"12"	"25"	"12"	"734"	"82.2"	"8.37"	"5101.23"	"43.00"	"11"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf14551, Pf17207, Pf17855"	"4174"	"ENSG00000100297"	"MCM5"	"hsa:4174; O60785; P33992; Q14578; Q9BTJ4; Q9BWL8"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"Cell cycle; Ciliary landscape; G1 to S cell cycle control; DNA replication; 10q11.21q11.23 copy number variation syndrome"	"11"	"0"	"781.8"	"895.7"	"3174.3"	"819.8"	"738.8"	"544.1"	"3478.0"	"360.6"	"558.6"	"427.3"	"433.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14008"	"Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3"	"6"	"12"	"26"	"12"	"2032"	"225.4"	"7.80"	"5063.42"	"42.66"	"11"	"11"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02985, Pf12348"	"9793"	"ENSG00000175216"	"CKAP5"	"hsa:9793; Q05D70; Q0VAX7; Q0VAX8; Q14008; Q14668; Q2TA89; Q6NSH4"	"Separation of Sister Chromatids; Regulation of PLK1 Activity at G2/M Transition; RHO GTPases Activate Formins; Resolution of Sister Chromatid Cohesion; Recruitment of NuMA to mitotic centrosomes; EML4 and NUDC in mitotic spindle formation; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	""	"13"	"0"	"831.6"	"831.2"	"2588.2"	"832.8"	"745.1"	"615.3"	"2399.1"	"304.6"	"415.5"	"362.3"	"359.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P48739"	"Phosphatidylinositol transfer protein beta isoform OS=Homo sapiens OX=9606 GN=PITPNB PE=1 SV=2"	"49"	"11"	"23"	"10"	"271"	"31.5"	"6.87"	"4172.68"	"42.22"	"9"	"10"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;ER/Golgi;other cell component"	"transporter activity;other molecular function"	"Pf02121"	"23760"	"ENSG00000180957"	"PITPNB"	"B3KYB8; B7Z7Q0; hsa:23760; P48739; Q8N5W1"	"PI and PC transport between ER and Golgi membranes"	""	"1"	"1"	"1254.0"	"1687.3"	"3864.6"	"1566.0"	"1834.0"	"1793.9"	"4981.1"	"1284.3"	"2158.3"	"1520.4"	"1678.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P16989"	"Y-box-binding protein 3 OS=Homo sapiens OX=9606 GN=YBX3 PE=1 SV=4"	"36"	"11"	"20"	"6"	"372"	"40.1"	"9.77"	"3122.45"	"42.19"	"8"	"10"	"stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00313"	"8531"	"ENSG00000060138"	"YBX3"	"B2RBW6; hsa:8531; P16989; Q14121; Q969N6; Q96B76"	""	"RalA downstream regulated genes; Apoptosis-related network due to altered Notch3 in ovarian cancer"	"2"	"6"	"712.8"	"695.3"	"2105.8"	"711.5"	"697.3"	"608.7"	"2390.9"	"400.1"	"639.0"	"478.4"	"516.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35232"	"Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1"	"48"	"12"	"27"	"12"	"272"	"29.8"	"5.76"	"5262.62"	"42.12"	"11"	"11"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01145"	"5245"	"ENSG00000167085"	"PHB1"	"B4DY47; hsa:5245; P35232; Q4VBQ0"	"RAF activation; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Processing of SMDT1"	""	"5"	"0"	"2016.8"	"2092.9"	"9097.8"	"1694.6"	"1300.5"	"1007.7"	"5986.9"	"498.9"	"946.8"	"684.8"	"657.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06744"	"Glucose-6-phosphate isomerase OS=Homo sapiens OX=9606 GN=GPI PE=1 SV=4"	"23"	"13"	"28"	"13"	"558"	"63.1"	"8.32"	"6551.29"	"41.93"	"12"	"10"	"other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00342"	"2821"	"ENSG00000105220"	"GPI"	"B4DG39; hsa:2821; P06744; Q9BRD3; Q9BSK5; Q9UHE6"	"Neutrophil degranulation; Glycolysis; Gluconeogenesis; TP53 Regulates Metabolic Genes"	"Cori cycle; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Aerobic glycolysis; N-glycan biosynthesis; Disorders of fructose metabolism; Glycolysis and gluconeogenesis; UDP-derived sugars synthesis in fibroblasts"	"12"	"0"	"1397.3"	"1877.7"	"7819.5"	"1711.7"	"1645.4"	"1381.9"	"10653.0"	"1200.5"	"1704.8"	"1223.9"	"1579.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14868"	"Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2"	"29"	"12"	"22"	"12"	"501"	"57.1"	"6.55"	"4746.73"	"41.81"	"11"	"11"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00152, Pf01336"	"1615"	"ENSG00000115866"	"DARS1"	"A8K3J2; D3DP77; hsa:1615; P14868; Q2TNI3; Q32Q69; Q53HV4; Q53YC5; Q68CR9; Q9BW52"	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"Alanine and aspartate metabolism"	"3"	"0"	"1020.4"	"1124.7"	"4343.1"	"955.8"	"829.1"	"629.4"	"4034.8"	"398.0"	"713.9"	"586.3"	"800.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50502"	"Hsc70-interacting protein OS=Homo sapiens OX=9606 GN=ST13 PE=1 SV=2"	"33"	"14"	"31"	"14"	"369"	"41.3"	"5.27"	"6758.25"	"41.80"	"14"	"10"	"other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf17830, Pf18253"	"6767"	"ENSG00000100380"	"ST13"	"hsa:6767; O14999; P50502; Q2TU77"	"Regulation of HSF1-mediated heat shock response"	""	"1"	"0"	"1540.7"	"2770.2"	"6036.1"	"2535.6"	"2478.7"	"2387.7"	"5143.9"	"1006.9"	"1364.4"	"1044.9"	"1100.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P24752"	"Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1"	"27"	"11"	"28"	"11"	"427"	"45.2"	"8.85"	"5259.70"	"41.74"	"11"	"9"	"other metabolic processes;stress response;developmental processes;other biological processes"	"mitochondrion;ER/Golgi"	"other molecular function"	"Pf00108, Pf02803"	"38"	"ENSG00000075239"	"ACAT1"	"B2R6H1; G3XAB4; hsa:38; P24752; Q96FG8"	"Branched-chain amino acid catabolism; Utilization of Ketone Bodies; Synthesis of Ketone Bodies"	"Fatty acid beta-oxidation; Tryptophan metabolism; SARS-CoV-2 and COVID-19 pathway"	"6"	"0"	"1111.7"	"1290.5"	"3494.4"	"1358.2"	"1305.7"	"1093.0"	"4378.2"	"952.3"	"1556.3"	"1693.4"	"3192.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16531"	"DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1"	"13"	"14"	"27"	"14"	"1140"	"126.9"	"5.26"	"4829.82"	"41.68"	"14"	"13"	"cell-cell signaling;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03178, Pf10433"	"1642"	"ENSG00000167986"	"DDB1"	"A6NG77; B2R648; B4DG00; hsa:1642; O15176; Q13289; Q16531; Q58F96"	"Neddylation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; DNA Damage Recognition in GG-NER; Dual Incision in GG-NER"	"Hippo-Merlin signaling dysregulation; Hepatitis B infection; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"14"	"0"	"905.4"	"1118.8"	"3634.1"	"1033.8"	"972.7"	"854.2"	"4227.0"	"685.5"	"960.5"	"798.5"	"931.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P67809"	"Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3"	"40"	"9"	"22"	"4"	"324"	"35.9"	"9.88"	"3957.40"	"41.53"	"8"	"8"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00313"	"4904"	"ENSG00000065978"	"YBX1"	"hsa:4904; P16990; P16991; P67809; Q14972; Q15325; Q5FVF0"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA; SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Interferon gamma signaling; mRNA Splicing - Minor Pathway; Noncanonical activation of NOTCH3"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; MECP2 and associated Rett syndrome; mRNA processing; Sudden infant death syndrome (SIDS) susceptibility pathways"	"10"	"0"	"172.8"	"195.7"	"494.1"	"166.1"	"164.4"	"142.1"	"556.0"	"115.6"	"157.9"	"121.0"	"128.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95782"	"AP-2 complex subunit alpha-1 OS=Homo sapiens OX=9606 GN=AP2A1 PE=1 SV=3"	"18"	"12"	"24"	"9"	"977"	"107.5"	"7.03"	"3725.49"	"41.36"	"9"	"11"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01602, Pf02296, Pf02883"	"160"	"ENSG00000196961"	"AP2A1"	"hsa:160; O95782; Q96CI7; Q96PP6; Q96PP7; Q9H070"	"MHC class II antigen presentation; Potential therapeutics for SARS; Recycling pathway of L1; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; LDL clearance; Trafficking of GluR2-containing AMPA receptors; Nef Mediated CD4 Down-regulation; Retrograde neurotrophin signalling; Nef Mediated CD8 Down-regulation; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; VLDLR internalisation and degradation"	"Synaptic vesicle pathway; VEGFA-VEGFR2 signaling; GABA receptor signaling; EGF/EGFR signaling pathway; Fragile X syndrome; mBDNF and proBDNF regulation of GABA neurotransmission"	"20"	"0"	"249.1"	"245.5"	"749.7"	"232.2"	"246.5"	"217.3"	"976.4"	"478.0"	"1392.6"	"1364.3"	"1687.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P18621"	"60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3"	"48"	"10"	"26"	"10"	"184"	"21.4"	"10.17"	"4571.31"	"41.34"	"10"	"10"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf00237"	"6139"	"ENSG00000265681"	"RPL17"	"B2R4H3; B4E3C2; B5ME31; hsa:6139; J3QL51; P18621; Q3KQW2; Q6NZ54; Q7M4M5"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"2491.9"	"2661.7"	"7827.1"	"2287.8"	"2066.3"	"1885.5"	"8519.8"	"824.5"	"1328.4"	"960.6"	"822.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y520"	"Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4"	"6"	"14"	"27"	"12"	"2896"	"316.7"	"9.13"	"4628.38"	"41.27"	"14"	"13"	"cell organization and biogenesis;other biological processes"	"cytosol;other cell component"	""	"Pf07001"	"23215"	"ENSG00000117523"	"PRRC2C"	"hsa:23215; Q05DM8; Q49A39; Q6PD54; Q9H2N2; Q9HA05; Q9NSM8; Q9NXL3; Q9UF29; Q9UPQ6; Q9Y520"	""	"VEGFA-VEGFR2 signaling"	"1"	"2"	"991.3"	"912.8"	"2379.9"	"891.6"	"895.7"	"797.6"	"4121.0"	"1095.2"	"1774.5"	"1429.1"	"1337.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62913"	"60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2"	"45"	"11"	"23"	"11"	"178"	"20.2"	"9.60"	"3748.80"	"41.04"	"7"	"10"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00281, Pf00673"	"6135"	"ENSG00000142676"	"RPL11"	"hsa:6135; P25121; P39026; P62913; Q8TDH2; Q9Y674"	"L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"2069.0"	"2130.8"	"6792.5"	"2030.7"	"1817.1"	"1702.0"	"7540.8"	"910.7"	"1399.2"	"1095.4"	"1045.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61981"	"14-3-3 protein gamma OS=Homo sapiens OX=9606 GN=YWHAG PE=1 SV=2"	"28"	"9"	"28"	"3"	"247"	"28.3"	"4.89"	"5404.05"	"41.04"	"9"	"9"	"transport;signal transduction;other biological processes"	"cytosol;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00244"	"7532"	"ENSG00000170027"	"YWHAG"	"hsa:7532; O70457; P35214; P61981; Q6FH52; Q9UDP2; Q9UN99"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Regulation of localization of FOXO transcription factors; TP53 Regulates Metabolic Genes; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Activation of BAD and translocation to mitochondria"	"Cell cycle; Prolactin signaling pathway; Myometrial relaxation and contraction pathways; Disruption of postsynaptic signaling by CNV; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"21"	"0"	"170.3"	"232.9"	"826.9"	"263.6"	"241.9"	"232.9"	"1193.4"	"210.8"	"302.5"	"255.2"	"267.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49736"	"DNA replication licensing factor MCM2 OS=Homo sapiens OX=9606 GN=MCM2 PE=1 SV=4"	"15"	"11"	"22"	"11"	"904"	"101.8"	"5.52"	"4529.47"	"41.01"	"10"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf12619, Pf14551, Pf17207, Pf17855"	"4171"	"ENSG00000073111"	"MCM2"	"hsa:4171; P49736; Q14577; Q15023; Q8N2V1; Q969W7; Q96AE1; Q9BRM7"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"Cell cycle; Ciliary landscape; G1 to S cell cycle control; DNA replication; 1p36 copy number variation syndrome; 10q11.21q11.23 copy number variation syndrome"	"12"	"0"	"812.3"	"813.9"	"2546.1"	"728.6"	"659.2"	"528.8"	"2875.4"	"341.1"	"487.3"	"449.5"	"373.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13283"	"Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1"	"30"	"12"	"21"	"10"	"466"	"52.1"	"5.52"	"3494.37"	"40.95"	"10"	"11"	"cell organization and biogenesis;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00076, Pf02136"	"10146"	"ENSG00000145907"	"G3BP1"	"hsa:10146; Q13283; Q5HYE9"	"SARS-CoV-2 activates/modulates innate and adaptive immune responses"	""	"1"	"2"	"464.3"	"543.7"	"1914.9"	"530.4"	"552.5"	"432.8"	"2433.7"	"340.5"	"491.9"	"424.1"	"419.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62269"	"40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3"	"51"	"12"	"30"	"12"	"152"	"17.7"	"10.99"	"6233.51"	"40.79"	"12"	"9"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00416"	"6222"	"ENSG00000096150; ENSG00000223367; ENSG00000226225; ENSG00000231500; ENSG00000235650"	"RPS18"	"hsa:6222; P25232; P62269; Q5SUJ3; Q6IPF8"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"2258.7"	"2573.7"	"7081.5"	"2149.9"	"1953.9"	"1694.3"	"7565.0"	"746.3"	"1163.8"	"899.8"	"893.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62241"	"40S ribosomal protein S8 OS=Homo sapiens OX=9606 GN=RPS8 PE=1 SV=2"	"47"	"10"	"21"	"10"	"208"	"24.2"	"10.32"	"2806.09"	"40.71"	"7"	"10"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01201"	"6202"	"ENSG00000142937"	"RPS8"	"hsa:6202; P09058; P62241; Q6IRL7"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"1697.8"	"1808.9"	"4730.4"	"1388.2"	"1368.1"	"1217.4"	"5138.4"	"780.1"	"1141.3"	"890.2"	"939.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95433"	"Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1"	"33"	"11"	"21"	"11"	"338"	"38.3"	"5.53"	"2810.93"	"40.67"	"7"	"11"	"other biological processes"	"cytosol;ER/Golgi"	"other molecular function"	"Pf08327, Pf09229"	"10598"	"ENSG00000100591"	"AHSA1"	"B2R9L2; B4DUR9; hsa:10598; O95433; Q96IL6; Q9P060"	""	"T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection"	"1"	"0"	"2097.6"	"1988.3"	"3762.8"	"2119.1"	"2016.5"	"2167.4"	"3182.8"	"900.8"	"1456.4"	"950.8"	"783.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P29692"	"Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5"	"36"	"13"	"26"	"12"	"281"	"31.1"	"5.01"	"5367.16"	"40.64"	"13"	"9"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00736, Pf10587"	"1936"	"ENSG00000104529; ENSG00000273594"	"EEF1D"	"B4DDU4; D3DWK3; E9PBQ9; hsa:1936; P29692; Q4VBZ6; Q969J1; Q96I38"	"Eukaryotic Translation Elongation"	"Translation factors"	"2"	"1"	"1748.9"	"2031.0"	"6803.2"	"1683.6"	"1354.9"	"1154.6"	"4325.5"	"747.5"	"1125.7"	"952.0"	"919.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P56192"	"Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2"	"18"	"10"	"18"	"10"	"900"	"101.1"	"6.16"	"3355.30"	"40.41"	"8"	"9"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00043, Pf00458, Pf09334, Pf18485, Pf19303"	"4141"	"ENSG00000166986"	"MARS1"	"B3KVK7; hsa:4141; P56192; Q14895; Q53H14; Q96A15; Q96BZ0; Q9NSE0"	"Cytosolic tRNA aminoacylation; Selenoamino acid metabolism"	""	"2"	"0"	"616.3"	"650.4"	"3159.1"	"589.2"	"585.3"	"414.3"	"3684.0"	"285.9"	"431.1"	"351.9"	"406.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P40429"	"60S ribosomal protein L13a OS=Homo sapiens OX=9606 GN=RPL13A PE=1 SV=2"	"40"	"11"	"27"	"11"	"203"	"23.6"	"10.93"	"4654.87"	"40.36"	"10"	"10"	"protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00572"	"23521"	"ENSG00000142541"	"RPL13A"	"A8K505; hsa:23521; P40429"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"15"	"0"	"1851.2"	"2041.7"	"6204.7"	"1730.3"	"1618.4"	"1473.6"	"6941.4"	"630.5"	"1006.9"	"676.2"	"625.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13162"	"Peroxiredoxin-4 OS=Homo sapiens OX=9606 GN=PRDX4 PE=1 SV=1"	"27"	"6"	"22"	"4"	"271"	"30.5"	"6.29"	"3592.88"	"40.33"	"4"	"6"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00578, Pf10417"	"10549"	"ENSG00000123131"	"PRDX4"	"hsa:10549; Q13162; Q6FHT3"	"Neutrophil degranulation"	"Selenium micronutrient network"	"2"	"0"	"79.9"	"98.9"	"585.4"	"110.4"	"110.1"	"65.9"	"730.6"	"60.2"	"98.6"	"64.0"	"51.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P10599"	"Thioredoxin OS=Homo sapiens OX=9606 GN=TXN PE=1 SV=3"	"78"	"7"	"20"	"7"	"105"	"11.7"	"4.92"	"3341.42"	"40.27"	"5"	"7"	"other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00085"	"7295"	"ENSG00000136810"	"TXN"	"B1ALW1; hsa:7295; O60744; P10599; Q53X69; Q96KI3; Q9UDG5"	"Detoxification of Reactive Oxygen Species; Oxidative Stress Induced Senescence; TP53 Regulates Metabolic Genes; Interconversion of nucleotide di- and triphosphates; The NLRP3 inflammasome; Purinergic signaling in leishmaniasis infection; Regulation of FOXO transcriptional activity by acetylation; Protein repair"	"Selenium micronutrient network; Folic acid network; Selenium micronutrient network ; Folic acid network; Selenium micronutrient network; TNF-alpha signaling pathway; Complement system; Nuclear receptors meta-pathway; NRF2 pathway; VEGFA-VEGFR2 signaling"	"18"	"0"	"905.1"	"1057.3"	"4626.9"	"1024.2"	"944.4"	"820.9"	"6775.7"	"730.2"	"865.2"	"692.7"	"715.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23528"	"Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3"	"71"	"14"	"28"	"9"	"166"	"18.5"	"8.09"	"6508.23"	"40.15"	"13"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf00241"	"1072"	"ENSG00000172757"	"CFL1"	"B3KUQ1; hsa:1072; P23528; Q53Y87; Q9UCA2"	"Platelet degranulation ; Regulation of actin dynamics for phagocytic cup formation; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; EPHB-mediated forward signaling; Sema3A PAK dependent Axon repulsion; RHO GTPases Activate ROCKs"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; VEGFA-VEGFR2 signaling; EGF/EGFR signaling pathway; Envelope proteins and their potential roles in EDMD physiopathology; 7q11.23 copy number variation syndrome; Neuroinflammation and glutamatergic signaling; CCL18 signaling pathway; Regulation of actin cytoskeleton; G13 signaling pathway"	"15"	"5"	"1594.2"	"1825.7"	"10458.0"	"2061.9"	"1270.0"	"943.0"	"14082.0"	"946.5"	"1251.9"	"913.1"	"787.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P53621"	"Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2"	"11"	"10"	"22"	"10"	"1224"	"138.3"	"7.66"	"3790.05"	"40.05"	"8"	"10"	"transport;signal transduction"	"non-structural extracellular;other membranes;cytosol;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00400, Pf04053, Pf06957, Pf12894"	"1314"	"ENSG00000122218"	"COPA"	"hsa:1314; P53621; Q5T201; Q8IXZ9"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport"	""	"2"	"0"	"851.6"	"916.8"	"2951.1"	"771.5"	"692.9"	"574.1"	"2144.5"	"277.2"	"420.2"	"361.4"	"388.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14174"	"Macrophage migration inhibitory factor OS=Homo sapiens OX=9606 GN=MIF PE=1 SV=4"	"45"	"7"	"23"	"7"	"115"	"12.5"	"7.88"	"3835.37"	"39.68"	"5"	"6"	"cell organization and biogenesis;other metabolic processes;stress response;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01187"	"4282"	"ENSG00000240972; ENSG00000276701"	"MIF"	"A5Z1R8; B2R4S3; hsa:4282; P14174; Q2V4Y5; Q6FHV0"	"Neutrophil degranulation; Cell surface interactions at the vascular wall; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	"Adipogenesis; Spinal cord injury"	"5"	"0"	"579.3"	"827.9"	"3546.5"	"786.2"	"768.0"	"546.9"	"4784.8"	"461.1"	"624.7"	"365.4"	"346.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55060"	"Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3"	"15"	"14"	"27"	"14"	"971"	"110.3"	"5.77"	"4661.18"	"39.64"	"13"	"12"	"transport"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf03378, Pf03810, Pf08506"	"1434"	"ENSG00000124207"	"CSE1L"	"A3RLL6; B2R5T4; E1P5Y0; F8W904; hsa:1434; O75432; P55060; Q32M40; Q9H5B7; Q9NTS0; Q9UP98; Q9UP99; Q9UPA0"	""	""	"0"	"0"	"1096.3"	"947.1"	"4236.0"	"944.2"	"720.4"	"497.6"	"3618.1"	"311.2"	"528.4"	"504.2"	"485.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y237"	"Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 OS=Homo sapiens OX=9606 GN=PIN4 PE=1 SV=1"	"47"	"7"	"30"	"7"	"131"	"13.8"	"9.77"	"5815.21"	"39.51"	"6"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13616"	"5303"	"ENSG00000102309"	"PIN4"	"A8E0G6; B3KXM0; F5H1P5; hsa:5303; Q0D2H3; Q3MHV0; Q52M21; Q5HYW6; Q6IRW4; Q9Y237"	""	""	"0"	"0"	"682.0"	"627.0"	"1950.2"	"651.7"	"635.6"	"420.2"	"7344.1"	"2081.8"	"3520.4"	"2850.2"	"3043.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P15531"	"Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1"	"48"	"7"	"26"	"3"	"152"	"17.1"	"6.19"	"4581.49"	"39.05"	"7"	"7"	"DNA metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"translation activity;kinase activity;other molecular function"	"Pf00334"	"4830"	"ENSG00000239672"	"NME1"	"hsa:4830; P15531; Q6FGK3; Q86XQ2; Q9UDJ6"	"Interconversion of nucleotide di- and triphosphates; Azathioprine ADME; Ribavirin ADME"	"Pyrimidine metabolism"	"4"	"7"	"1358.3"	"1455.8"	"7199.5"	"1459.5"	"967.9"	"630.2"	"6776.7"	"525.0"	"627.7"	"523.7"	"486.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62081"	"40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1"	"43"	"11"	"21"	"11"	"194"	"22.1"	"10.10"	"3312.64"	"38.98"	"7"	"10"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf01251"	"6201"	"ENSG00000171863"	"RPS7"	"hsa:6201; P23821; P24818; P62081; Q57Z92; Q6IPH1"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery; rRNA modification in the nucleus and cytosol"	"Cytoplasmic ribosomal proteins"	"20"	"0"	"1796.5"	"1837.0"	"5268.6"	"1549.3"	"1383.7"	"1235.0"	"4880.3"	"468.8"	"773.6"	"533.2"	"556.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P18669"	"Phosphoglycerate mutase 1 OS=Homo sapiens OX=9606 GN=PGAM1 PE=1 SV=2"	"54"	"9"	"18"	"9"	"254"	"28.8"	"7.18"	"3189.98"	"38.97"	"6"	"9"	"other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;other cell component"	"other molecular function"	"Pf00300"	"5223"	"ENSG00000171314"	"PGAM1"	"hsa:5223; P18669; Q9BWC0"	"Neutrophil degranulation; Glycolysis; Gluconeogenesis"	"Cori cycle; Metabolic reprogramming in colon cancer; Glycolysis and gluconeogenesis"	"6"	"0"	"561.2"	"767.8"	"3111.1"	"590.8"	"596.4"	"330.4"	"3451.3"	"357.9"	"403.2"	"241.2"	"231.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P32969"	"60S ribosomal protein L9 OS=Homo sapiens OX=9606 GN=RPL9 PE=1 SV=1"	"51"	"8"	"24"	"8"	"192"	"21.9"	"9.95"	"4974.36"	"38.92"	"7"	"5"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00347"	"6133"	"ENSG00000163682"	"RPL9; RPL9P7; RPL9P8; RPL9P9"	"hsa:6133; P32969"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"1016.6"	"1160.1"	"3360.2"	"1025.4"	"966.8"	"830.4"	"4134.9"	"439.6"	"639.4"	"443.3"	"423.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13642"	"Four and a half LIM domains protein 1 OS=Homo sapiens OX=9606 GN=FHL1 PE=1 SV=4"	"25"	"7"	"15"	"7"	"323"	"36.2"	"8.97"	"2190.95"	"38.86"	"4"	"6"	"other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00412"	"2273"	"ENSG00000022267"	"FHL1"	"B7Z5T4; B7Z793; hsa:2273; O95212; Q13230; Q13642; Q13645; Q5JXI7; Q5M7Y6; Q6IB30; Q9NZ40; Q9UKZ8; Q9Y630"	""	"Notch signaling pathway"	"1"	"0"	"1174.7"	"1431.3"	"2786.9"	"1506.3"	"1332.5"	"1254.6"	"3252.9"	"787.0"	"1051.6"	"827.6"	"1058.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q02878"	"60S ribosomal protein L6 OS=Homo sapiens OX=9606 GN=RPL6 PE=1 SV=3"	"44"	"14"	"29"	"14"	"288"	"32.7"	"10.58"	"5948.65"	"38.83"	"13"	"11"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01159, Pf03868"	"6128"	"ENSG00000089009"	"RPL6"	"hsa:6128; Q02878; Q2M3Q3; Q8WW97"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"4275.1"	"4510.3"	"13928.9"	"3897.2"	"3525.7"	"3159.8"	"12315.1"	"1174.9"	"1946.1"	"1333.7"	"1245.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P26599"	"Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1"	"29"	"12"	"22"	"11"	"531"	"57.2"	"9.17"	"4676.87"	"38.53"	"8"	"10"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf11835, Pf13893"	"749887"	"ENSPPYG00000009289; ENSPTRG00000010165"	"PTBP1"	"A0A2J8IKP3; A0A2J8RA51; A0A6D2WFY9; A0A8I5YPF9; K7AXA8"	""	""	"0"	"2"	"1243.0"	"1174.8"	"3195.1"	"1019.4"	"973.1"	"844.8"	"4101.6"	"1084.1"	"1396.5"	"1048.3"	"1345.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43707"	"Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2"	"15"	"12"	"24"	"6"	"911"	"104.8"	"5.44"	"4959.83"	"38.33"	"11"	"11"	"cell organization and biogenesis;RNA metabolism OR transcription;stress response;transport;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00307, Pf00435, Pf08726"	"81"	"ENSG00000130402; ENSG00000282844"	"ACTN4"	"A4K467; D6PXK4; hsa:81; O43707; O76048"	"Platelet degranulation ; Nephrin family interactions"	"Arrhythmogenic right ventricular cardiomyopathy; Primary focal segmental glomerulosclerosis (FSGS); Focal adhesion; Striated muscle contraction pathway; Ebola virus infection in host; Nephrotic syndrome; Alstrom syndrome"	"9"	"6"	"569.9"	"565.4"	"2977.3"	"556.8"	"516.2"	"363.8"	"3974.6"	"295.6"	"379.3"	"347.1"	"325.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51610"	"Host cell factor 1 OS=Homo sapiens OX=9606 GN=HCFC1 PE=1 SV=2"	"7"	"11"	"20"	"11"	"2035"	"208.6"	"7.46"	"3729.44"	"38.07"	"9"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf01344, Pf13415"	"3054"	"ENSG00000172534"	"HCFC1"	"hsa:3054; P51610; Q6P4G5"	"UCH proteinases; Formation of WDR5-containing histone-modifying complexes; Transcriptional activation of mitochondrial biogenesis; HATs acetylate histones"	"Mitochondrial gene expression; Pleural mesothelioma"	"6"	"0"	"865.2"	"915.4"	"2365.4"	"845.9"	"785.3"	"665.3"	"3626.3"	"1039.4"	"1467.3"	"1208.0"	"1323.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q58FG1"	"Putative heat shock protein HSP 90-alpha A4 OS=Homo sapiens OX=9606 GN=HSP90AA4P PE=5 SV=1"	"9"	"4"	"21"	"1"	"418"	"47.7"	"5.19"	"4096.76"	"38.07"	"4"	"3"	"stress response;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00183, Pf13589"	""	""	"HSP90AA4P"	"Q58FG1"	""	""	"0"	"0"	"70.7"	"98.0"	"355.7"	"78.4"	"65.5"	"51.4"	"275.9"	"29.1"	"39.9"	"23.4"	"19.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07910"	"Heterogeneous nuclear ribonucleoproteins C1/C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4"	"31"	"12"	"25"	"12"	"306"	"33.7"	"5.08"	"5789.81"	"37.83"	"10"	"8"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"3183"	"ENSG00000092199"	"HNRNPC"	"D3DS19; D3DS22; hsa:3183; P07910; P22628; Q53EX2; Q59FD3; Q5FWE8; Q86SF8; Q86U45; Q96HK7; Q96HM4; Q96IY5; Q9BTS3"	"SUMOylation of RNA binding proteins; mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle"	"mRNA processing"	"6"	"0"	"1400.6"	"1389.0"	"4808.3"	"1285.7"	"1273.7"	"1035.5"	"6063.3"	"666.1"	"1170.7"	"807.2"	"750.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96AG4"	"Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1"	"28"	"9"	"21"	"9"	"307"	"34.9"	"9.57"	"3305.26"	"37.69"	"7"	"8"	""	"other membranes;mitochondrion;ER/Golgi;nucleus;other cell component"	""	"Pf13855"	"55379"	"ENSG00000108829"	"LRRC59"	"B2RE83; D3DTX8; hsa:55379; Q96AG4; Q9P189"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"917.6"	"955.4"	"2995.9"	"879.9"	"766.5"	"644.3"	"2722.5"	"317.6"	"491.7"	"481.4"	"514.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25205"	"DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3"	"18"	"11"	"20"	"11"	"808"	"90.9"	"5.77"	"4633.49"	"37.67"	"10"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf14551, Pf17207, Pf17855"	"4172"	"ENSG00000112118"	"MCM3"	"B4DWW4; hsa:4172; P25205; Q92660; Q9BTR3; Q9NUE7"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"Cell cycle; Retinoblastoma gene in cancer; Ciliary landscape; G1 to S cell cycle control; DNA replication; 10q11.21q11.23 copy number variation syndrome"	"12"	"0"	"464.6"	"492.6"	"1802.7"	"510.9"	"476.1"	"355.1"	"2085.5"	"242.3"	"374.0"	"357.3"	"321.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P67936"	"Tropomyosin alpha-4 chain OS=Homo sapiens OX=9606 GN=TPM4 PE=1 SV=3"	"37"	"10"	"23"	"4"	"248"	"28.5"	"4.69"	"4450.97"	"37.62"	"10"	"9"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton"	"cytoskeletal activity;other molecular function"	"Pf00261"	"7171"	"ENSG00000167460"	"TPM4"	"hsa:7171; P07226; P67936; Q15659; Q5U0D9; Q9BU85; Q9H8Q3; Q9UCS1; Q9UCS2; Q9UCS3; Q9UCS4"	"Smooth Muscle Contraction; RHOV GTPase cycle; Signaling by ALK fusions and activated point mutants; Striated Muscle Contraction"	"Striated muscle contraction pathway"	"5"	"0"	"306.4"	"329.6"	"1344.5"	"331.9"	"259.2"	"199.8"	"1705.8"	"213.7"	"290.6"	"215.2"	"186.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99460"	"26S proteasome non-ATPase regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PSMD1 PE=1 SV=2"	"11"	"10"	"22"	"10"	"953"	"105.8"	"5.39"	"4344.17"	"37.59"	"10"	"9"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf01851, Pf13646, Pf18004"	"5707"	"ENSG00000173692"	"PSMD1"	"B8ZZH9; hsa:5707; Q24JU0; Q53TI2; Q6GMU5; Q6P2P4; Q6PJM7; Q6PKG9; Q86VU1; Q8IV79; Q99460"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Neutrophil degranulation"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"64"	"0"	"928.3"	"1058.7"	"3291.6"	"929.5"	"880.5"	"730.7"	"2949.9"	"418.4"	"587.4"	"496.6"	"532.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92616"	"eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6"	"5"	"11"	"26"	"11"	"2671"	"292.6"	"7.47"	"5166.10"	"37.52"	"11"	"10"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"457.5"	"494.5"	"1882.3"	"421.0"	"370.2"	"276.3"	"2012.5"	"168.2"	"257.6"	"223.6"	"268.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P27635"	"60S ribosomal protein L10 OS=Homo sapiens OX=9606 GN=RPL10 PE=1 SV=4"	"49"	"9"	"23"	"9"	"214"	"24.6"	"10.08"	"4350.17"	"37.20"	"7"	"8"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00252"	"100137264; 100146244; 100172946; 100415355; 100468790; 100724614; 100982236; 101083663; 101136536; 101344695; 101444008; 101539056; 101690567; 101867181; 101975002; 102028809; 102257301; 102442647; 102878669; 102890423; 102923570; 102957760; 103127392; 103211225; 103250904; 103731218; 104667036; 104872587; 105294701; 105302495; 105467951; 105521640; 105579731; 105727260; 105824536; 105867804; 106000161; 107160308; 108513162; 108518769; 109696857; 110954; 465944; 700795; 81764"	"ENSAMEG00000000227; ENSANAG00000036053; ENSCAFG00020009114; ENSCAFG00030015144; ENSCAFG00040021422; ENSCAFG00845028627; ENSCANG00000032226; ENSCATG00000030970; ENSCCAG00000024992; ENSCGRG00001008387; ENSCJAG00000011822; ENSCLAG00000003108; ENSCPOG00000002355; ENSECAG00000017154; ENSFCAG00000011395; ENSGGOG00000000131; ENSLCNG00005021252; ENSMFAG00000040824; ENSMLUG00000014337; ENSMMMG00000014279; ENSMMUG00000005494; ENSMNEG00000038094; ENSMPUG00000009320; ENSMUSG00000008682; ENSMUSG00000058443; ENSNGAG00000023746; ENSNLEG00000028143; ENSNVIG00000023818; ENSPANG00000008309; ENSPCOG00000027122; ENSPPAG00000034160; ENSPPYG00000020874; ENSPSMG00000015404; ENSPTIG00000005599; ENSPTRG00000043378; ENSRBIG00000042996; ENSRNOG00000056765; ENSRROG00000019247; ENSSSUG00005010590; ENSSTOG00000011857; ENSTGEG00000012563; ENSUAMG00000020454; ENSUMAG00000019583; ENSUPAG00010000252"	"LOC100768740; LOC101344695; LOC105294701; LOC112632580; Rpl10; RPL10"	"A0A091D943; A0A1S3APJ4; A0A1S3GPT7; A0A1U7SU42; A0A250YCK6; A0A286XQR8; A0A2I3FV08; A0A2J8IN69; A0A2J8RLU6; A0A2K5EV78; A0A2K5ILK8; A0A2K5LLF2; A0A2K5QER4; A0A2K5U275; A0A2K6D043; A0A2K6GRP4; A0A2K6MTH0; A0A2K6NK39; A0A2R9B361; A0A2Y9G5G6; A0A384DKX1; A0A3Q0CF07; A0A3Q7NJC4; A0A452S2Z9; A0A485PEW4; A0A667IJV2; A0A673U4F8; A0A6D2WIN2; A0A6D2XTB8; A0A6I9ME29; A0A6J0A9X4; A0A6J2E7G1; A0A6J3GU06; A0A6P3QFP2; A0A6P5P1X6; A0A6P6DLY1; A0A7J7YFN8; A0A7J8J7V5; A0A822A0T4; A0A8B7B976; A0A8B7FW91; A0A8C0K7J7; A0A8C0TBM4; A0A8C2LMI8; A0A8C2UVN1; A0A8C5ZPE8; A0A8C6S1T7; A0A8C7BXJ2; A0A8C8ZPD3; A0A8C9J452; A0A8D2F5T2; A0A8D2GF85; A0A8I3PXJ3; A0A8J8XDM4; A0A8M1M1S6; A0A9B0U593; A2AM97; A6KRS1; A9CB60; aju:106987320; aml:100468790; B0KWW6; B1MTV1; B3RFD9; C3PT02; cang:105521640; caty:105579731; ccan:109696857; cpoc:100724614; csyr:103250904; D3YC00; dnm:101444008; dord:106000161; ecb:100146244; F7AYR2; F7GKJ8; fca:101083663; G1PPT9; G2HFW2; G3S9Q9; G7Q3B3; ggo:101136536; H2PX84; I2CYS4; I3MI39; L5KDV0; L8Y8T7; M3WF14; M3YD39; mcal:110286529; mcc:700795; mcf:101867181; mlf:102442647; mmu:110954; mmur:105867804; mni:105467951; mpuf:101690567; myb:102257301; nsu:110578606; P45634; pale:102878669; pale:102890423; panu:100137264; pcoq:105824536; pps:100982236; ptg:102957760; ptr:465944; pvp:105294701; pvp:105302495; Q569M8; Q5M9K8; Q6PDV7; Q6ZWV3; rbb:108513162; rbb:108518769; rno:81764; rro:104667036; S7NR49; sara:101539056; tmu:101344695; umr:103679662; zca:113931110"	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; SRP-dependent cotranslational protein targeting to membrane; Major pathway of rRNA processing in the nucleolus and cytosol; L13a-mediated translational silencing of Ceruloplasmin expression; SRP-dependent cotranslational protein targeting to membrane; Major pathway of rRNA processing in the nucleolus and cytosol; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"15"	"0"	"1701.8"	"1696.0"	"5199.5"	"1657.3"	"1540.2"	"1265.2"	"5449.9"	"677.0"	"996.4"	"690.3"	"683.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13310"	"Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1"	"16"	"10"	"22"	"5"	"644"	"70.7"	"9.26"	"3932.82"	"37.07"	"9"	"10"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf00658"	"8761"	"ENSG00000090621"	"PABPC4"	"B1ANQ8; hsa:8761; Q13310; Q4VC03; Q6P0N3"	""	""	"0"	"0"	"457.3"	"532.6"	"1787.0"	"495.3"	"508.1"	"394.5"	"2287.2"	"262.6"	"362.6"	"284.8"	"298.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15393"	"Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4"	"11"	"11"	"22"	"11"	"1217"	"135.5"	"5.26"	"4113.01"	"36.93"	"11"	"11"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03178, Pf10433"	"23450"	"ENSG00000189091"	"SF3B3"	"hsa:23450; Q15393; Q6NTI8; Q96GC0; Q9BPY2; Q9UFX7; Q9UJ29"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"mRNA processing"	"3"	"0"	"756.9"	"822.3"	"2677.7"	"865.0"	"801.9"	"684.9"	"2759.3"	"391.9"	"612.4"	"477.1"	"512.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30050"	"60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1"	"73"	"11"	"23"	"11"	"165"	"17.8"	"9.42"	"4531.78"	"36.74"	"10"	"8"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00298, Pf03946"	"6136"	"ENSG00000197958"	"RPL12"	"hsa:6136; P30050; Q5VVV2; Q6PB27"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"2169.4"	"2256.9"	"7860.0"	"2079.7"	"1619.8"	"1422.2"	"8107.8"	"694.4"	"989.9"	"693.0"	"680.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P24534"	"Elongation factor 1-beta OS=Homo sapiens OX=9606 GN=EEF1B2 PE=1 SV=3"	"43"	"12"	"27"	"11"	"225"	"24.7"	"4.67"	"4766.29"	"36.73"	"11"	"9"	"protein metabolism;other metabolic processes"	"cytosol;other cell component"	"enzyme regulator activity;nucleic acid binding activity"	"Pf00736, Pf10587"	"1933"	"ENSG00000114942; ENSG00000283391"	"EEF1B2"	"A8K795; hsa:1933; P24534; Q6IBH9"	"Eukaryotic Translation Elongation"	"Translation factors"	"2"	"0"	"1481.7"	"2267.9"	"5298.0"	"1991.8"	"1905.6"	"1756.1"	"4918.5"	"1423.1"	"2313.1"	"1989.8"	"2116.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15181"	"Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2"	"47"	"11"	"17"	"11"	"289"	"32.6"	"5.86"	"2867.98"	"36.66"	"8"	"9"	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00719"	"5464"	"ENSG00000180817"	"PPA1"	"hsa:5464; Q15181; Q2M348; Q5SQT7; Q6P7P4; Q9UQJ5; Q9Y5B1"	"Cytosolic tRNA aminoacylation; Pyrophosphate hydrolysis"	""	"2"	"0"	"491.1"	"592.1"	"3189.2"	"598.0"	"530.1"	"387.4"	"4418.5"	"411.4"	"559.7"	"497.1"	"1281.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P26641"	"Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3"	"31"	"16"	"29"	"16"	"437"	"50.1"	"6.67"	"5685.62"	"36.63"	"15"	"12"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity"	"Pf00043, Pf00647, Pf02798"	"1937"	"ENSG00000254772"	"EEF1G"	"B4DTG2; hsa:1937; P26641; Q6PJ62; Q6PK31; Q96CU2; Q9P196"	"Signaling by ALK fusions and activated point mutants; Eukaryotic Translation Elongation"	"Translation factors"	"3"	"0"	"1705.9"	"2295.0"	"7608.0"	"2229.2"	"1829.3"	"1649.3"	"7261.1"	"1196.1"	"2135.2"	"1743.3"	"1835.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50570"	"Dynamin-2 OS=Homo sapiens OX=9606 GN=DNM2 PE=1 SV=2"	"10"	"7"	"17"	"4"	"870"	"98.0"	"7.44"	"3441.64"	"36.34"	"6"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00169, Pf00350, Pf01031, Pf02212"	"1785"	"ENSG00000079805"	"DNM2"	"A8K1B6; E7EV30; E9PEQ4; hsa:1785; K7ESI9; P50570; Q5I0Y0; Q7Z5S3; Q9UPH4"	"MHC class II antigen presentation; Lysosome Vesicle Biogenesis; Golgi Associated Vesicle Biogenesis; Clathrin-mediated endocytosis; Recycling pathway of L1; NGF-stimulated transcription; Toll Like Receptor 4 (TLR4) Cascade; NOSTRIN mediated eNOS trafficking; Retrograde neurotrophin signalling; Formation of annular gap junctions"	"Synaptic vesicle pathway; Fragile X syndrome; Intracellular trafficking proteins involved in CMT neuropathy"	"14"	"3"	"515.7"	"548.6"	"1653.0"	"495.0"	"465.6"	"335.6"	"1583.9"	"331.7"	"509.3"	"529.6"	"692.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q07666"	"KH domain-containing, RNA-binding, signal transduction-associated protein 1 OS=Homo sapiens OX=9606 GN=KHDRBS1 PE=1 SV=1"	"18"	"9"	"20"	"9"	"443"	"48.2"	"8.66"	"4176.53"	"36.27"	"8"	"8"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf16274, Pf16568"	"10657"	"ENSG00000121774"	"KHDRBS1"	"D3DPP3; hsa:10657; Q07666; Q6PJX7; Q8NB97; Q99760"	"PTK6 Regulates Proteins Involved in RNA Processing"	"Leptin signaling pathway; Primary ovarian insufficiency"	"3"	"0"	"1131.1"	"1228.9"	"2430.3"	"1121.0"	"1069.0"	"1105.2"	"2820.5"	"421.7"	"664.1"	"520.5"	"544.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62249"	"40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2"	"65"	"11"	"26"	"11"	"146"	"16.4"	"10.21"	"4961.55"	"36.02"	"11"	"10"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00380"	"6217"	"ENSG00000105193"	"RPS16"	"B2RDD5; hsa:6217; P17008; P62249"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"2309.8"	"2459.8"	"6432.3"	"1943.1"	"1795.0"	"1580.6"	"7415.0"	"895.2"	"1225.6"	"903.7"	"854.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07237"	"Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3"	"22"	"10"	"21"	"10"	"508"	"57.1"	"4.87"	"2910.87"	"35.93"	"8"	"10"	"protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00085, Pf13848"	"5034"	"ENSG00000185624"	"P4HB"	"B2RDQ2; hsa:5034; P07237; P30037; P32079; Q15205; Q6LDE5"	"Hedgehog ligand biogenesis; Collagen biosynthesis and modifying enzymes; Detoxification of Reactive Oxygen Species; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Insulin processing; Interleukin-12 signaling; Interleukin-23 signaling; Chylomicron assembly; VLDL assembly; LDL remodeling"	"VEGFA-VEGFR2 signaling; Type I collagen synthesis in the context of osteogenesis imperfecta"	"13"	"0"	"732.7"	"905.5"	"3716.8"	"845.4"	"746.1"	"592.4"	"5237.1"	"598.1"	"834.5"	"637.1"	"545.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63241"	"Eukaryotic translation initiation factor 5A-1 OS=Homo sapiens OX=9606 GN=EIF5A PE=1 SV=2"	"45"	"6"	"22"	"6"	"154"	"16.8"	"5.24"	"4787.62"	"35.79"	"5"	"5"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf01287"	"1984"	"ENSG00000132507; ENSG00000288145"	"EIF5A"	"A8K9A0; D3DTP2; hsa:1984; P10159; P63241; Q16182; Q7L7L3; Q7Z4L1; Q9D0G2"	"Hypusine synthesis from eIF5A-lysine"	"Translation factors; eIF5A regulation in response to inhibition of the nuclear export system"	"3"	"0"	"1127.6"	"1302.1"	"3583.3"	"1313.9"	"1151.6"	"1056.1"	"4124.5"	"612.6"	"2143.0"	"3415.9"	"6343.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P38919"	"Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4"	"23"	"10"	"22"	"7"	"411"	"46.8"	"6.73"	"4982.16"	"35.74"	"10"	"8"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"9775"	"ENSG00000141543"	"EIF4A3"	"hsa:9775; P38919; Q15033; Q6IBQ2; Q96A18"	"mRNA Splicing - Major Pathway; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Deadenylation of mRNA; ISG15 antiviral mechanism; Transport of Mature mRNA derived from an Intron-Containing Transcript"	""	"8"	"0"	"600.3"	"597.1"	"2157.2"	"578.2"	"531.1"	"404.9"	"2769.2"	"337.1"	"544.1"	"387.4"	"463.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04181"	"Ornithine aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OAT PE=1 SV=1"	"27"	"8"	"16"	"8"	"439"	"48.5"	"7.03"	"3201.34"	"35.73"	"7"	"8"	"other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00202"	"4942"	"ENSG00000065154"	"OAT"	"D3DRF0; hsa:4942; P04181; Q16068; Q16069; Q68CS0; Q6IAV9; Q9UD03"	"Glutamate and glutamine metabolism"	"Amino acid metabolism; 22q11.2 copy number variation syndrome; Creatine pathway"	"4"	"0"	"545.8"	"654.9"	"3084.0"	"618.9"	"542.4"	"353.0"	"4139.0"	"365.5"	"526.4"	"360.7"	"356.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62263"	"40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3"	"41"	"6"	"17"	"6"	"151"	"16.3"	"10.05"	"2944.53"	"35.45"	"4"	"6"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00411"	"6208"	"ENSG00000164587"	"RPS14"	"B2R5G5; D3DQG5; hsa:6208; P06366; P62263; Q5BJI0"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; rRNA modification in the nucleus and cytosol; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"20"	"0"	"530.8"	"560.9"	"1535.4"	"466.2"	"479.3"	"376.9"	"2176.0"	"230.9"	"379.4"	"277.1"	"250.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62829"	"60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1"	"54"	"8"	"16"	"8"	"140"	"14.9"	"10.51"	"3163.67"	"35.42"	"6"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00238"	"9349"	"ENSG00000125691"	"RPL23"	"hsa:9349; P23131; P24048; P62829; Q29246; Q3SWV7; Q6P5S1"	"Regulation of expression of SLITs and ROBOs; SRP-dependent cotranslational protein targeting to membrane; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins; 17q12 copy number variation syndrome"	"15"	"0"	"1449.4"	"1576.5"	"4687.3"	"1340.5"	"1214.1"	"1080.1"	"4717.8"	"504.8"	"702.0"	"545.1"	"504.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92688"	"Acidic leucine-rich nuclear phosphoprotein 32 family member B OS=Homo sapiens OX=9606 GN=ANP32B PE=1 SV=1"	"28"	"8"	"16"	"5"	"251"	"28.8"	"4.06"	"2509.91"	"35.12"	"6"	"6"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf12799"	"10541"	"ENSG00000136938"	"ANP32B"	"B2R9C7; hsa:10541; O00655; P78458; P78459; Q92688"	""	""	"0"	"3"	"580.3"	"821.0"	"2745.8"	"848.9"	"752.4"	"675.5"	"4428.3"	"970.3"	"1449.2"	"911.7"	"955.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P39687"	"Acidic leucine-rich nuclear phosphoprotein 32 family member A OS=Homo sapiens OX=9606 GN=ANP32A PE=1 SV=1"	"26"	"7"	"15"	"4"	"249"	"28.6"	"4.09"	"2369.04"	"35.11"	"6"	"6"	"transport;signal transduction;other biological processes"	"ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf14580"	"8125"	"ENSG00000140350"	"ANP32A"	"B2R6T4; hsa:8125; P39687; Q53FK4; Q5J8L8; Q7M4N6"	"HuR (ELAVL1) binds and stabilizes mRNA"	"IL-18 signaling pathway"	"2"	"0"	"233.8"	"342.0"	"1104.7"	"328.3"	"328.1"	"281.6"	"1789.4"	"400.1"	"509.3"	"374.1"	"397.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13838"	"Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1"	"24"	"9"	"20"	"9"	"428"	"49.0"	"5.67"	"3389.87"	"35.11"	"8"	"9"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"7919"	"ENSG00000198563; ENSG00000215425; ENSG00000225073; ENSG00000225859; ENSG00000229496; ENSG00000230624; ENSG00000235439"	"DDX39B"	"B0S8C0; hsa:7919; O43496; Q0EFA1; Q13838; Q2L6F9; Q53GL9; Q5RJ64; Q5RJ66; Q5ST94; Q5STB4; Q5STB5; Q5STB7; Q5STB8; Q5STU4; Q5STU5; Q5STU6; Q5STU8; Q71V76"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; RHOBTB2 GTPase cycle"	""	"5"	"0"	"605.8"	"717.6"	"2856.5"	"801.2"	"609.1"	"442.5"	"3102.7"	"349.5"	"443.0"	"355.5"	"438.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P99999"	"Cytochrome c OS=Homo sapiens OX=9606 GN=CYCS PE=1 SV=2"	"46"	"6"	"21"	"6"	"105"	"11.7"	"9.57"	"4002.16"	"35.11"	"6"	"5"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"other membranes;cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf00034"	"54205"	"ENSG00000172115"	"CYCS"	"A4D166; B2R4I1; hsa:54205; P00001; P99999; Q6NUR2; Q6NX69; Q96BV4"	"Respiratory electron transport; Detoxification of Reactive Oxygen Species; Transcriptional activation of mitochondrial biogenesis; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1; Activation of caspases through apoptosome-mediated cleavage; SMAC (DIABLO) binds to IAPs ; SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes ; Regulation of the apoptosome activity; Release of apoptotic factors from the mitochondria; Pyroptosis"	"miRNA regulation of DNA damage response; Apoptosis modulation and signaling; Alzheimer's disease and miRNA effects; AGE/RAGE pathway; Parkinson's disease pathway; Nanomaterial induced apoptosis; Apoptosis; Fas ligand pathway and stress induction of heat shock proteins; Apoptosis modulation by HSP70; VEGFA-VEGFR2 signaling; Oxidative damage response; NO/cGMP/PKG mediated neuroprotection; Chromosomal and microsatellite instability in colorectal cancer ; Non-small cell lung cancer; Acute viral myocarditis; Nonalcoholic fatty liver disease; Measles virus infection; Small cell lung cancer; Hepatitis B infection; IL-18 signaling pathway; Pleural mesothelioma; Complement system in neuronal development and plasticity; Alzheimer's disease; DNA damage response"	"36"	"0"	"802.7"	"595.2"	"1426.6"	"869.9"	"468.8"	"300.8"	"6307.4"	"1917.9"	"2496.3"	"2254.9"	"3239.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15046"	"Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3"	"18"	"9"	"17"	"9"	"597"	"68.0"	"6.35"	"3146.09"	"34.90"	"8"	"9"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00152, Pf01336"	"3735"	"ENSG00000065427"	"KARS1"	"A8MSK1; D3DUK4; hsa:3735; O14946; Q15046; Q96J25; Q9HB23"	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation; Mitochondrial tRNA aminoacylation"	""	"3"	"0"	"720.9"	"816.4"	"2731.7"	"740.3"	"672.6"	"492.7"	"2975.4"	"541.3"	"821.6"	"731.0"	"920.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35637"	"RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1"	"16"	"7"	"16"	"5"	"526"	"53.4"	"9.36"	"2822.53"	"34.78"	"5"	"7"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00641"	"2521"	"ENSG00000089280"	"FUS"	"hsa:2521; P35637; Q9H4A8"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"MECP2 and associated Rett syndrome; mRNA processing"	"4"	"2"	"1346.0"	"1525.4"	"3228.9"	"1413.7"	"1295.3"	"1278.9"	"3922.1"	"778.8"	"1195.4"	"876.0"	"915.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06753"	"Tropomyosin alpha-3 chain OS=Homo sapiens OX=9606 GN=TPM3 PE=1 SV=2"	"30"	"10"	"24"	"3"	"285"	"32.9"	"4.72"	"4350.86"	"34.75"	"10"	"10"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton"	"cytoskeletal activity"	"Pf00261"	"7170"	"ENSG00000143549"	"TPM3"	"D3DV71; hsa:7170; P06753; P12324; Q2QD06; Q5VU58; Q5VU63; Q5VU66; Q5VU71; Q5VU72; Q8TCG3; Q969Q2; Q9NQH8"	"RHOV GTPase cycle; Signaling by ALK fusions and activated point mutants; Smooth Muscle Contraction; Striated Muscle Contraction"	"Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4); Striated muscle contraction pathway; VEGFA-VEGFR2 signaling"	"7"	"7"	"1232.5"	"1444.9"	"8050.0"	"1514.8"	"1213.2"	"1080.7"	"9491.8"	"894.9"	"1480.3"	"929.1"	"828.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14558"	"Phosphoribosyl pyrophosphate synthase-associated protein 1 OS=Homo sapiens OX=9606 GN=PRPSAP1 PE=1 SV=2"	"34"	"9"	"19"	"6"	"356"	"39.4"	"7.20"	"3882.33"	"34.56"	"9"	"8"	"other metabolic processes"	"other cell component"	"enzyme regulator activity;other molecular function"	"Pf13793, Pf14572"	"5635"	"ENSG00000161542"	"PRPSAP1"	"B2R6M4; hsa:5635; Q14558; Q96H06"	""	""	"0"	"0"	"209.6"	"250.4"	"759.5"	"254.5"	"255.4"	"203.3"	"757.4"	"172.5"	"359.1"	"417.4"	"541.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62753"	"40S ribosomal protein S6 OS=Homo sapiens OX=9606 GN=RPS6 PE=1 SV=1"	"33"	"12"	"26"	"12"	"249"	"28.7"	"10.84"	"5302.58"	"34.50"	"12"	"9"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01092"	"6194"	"ENSG00000137154"	"RPS6"	"hsa:6194; P08227; P10660; P62753; Q4VBY7; Q8N6Z7"	"Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SARS-CoV-2 modulates host translation machinery; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; mTORC1-mediated signalling; rRNA modification in the nucleus and cytosol; Nuclear events stimulated by ALK signaling in cancer; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"IL-5 signaling pathway; Thyroid stimulating hormone (TSH) signaling pathway; Leptin signaling pathway; Follicle stimulating hormone (FSH) signaling pathway; Prolactin signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; Interleukin-11 signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Kit receptor signaling pathway; MECP2 and associated Rett syndrome; VEGFA-VEGFR2 signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Thermogenesis; Translation inhibitors in chronically activated PDGFRA cells; Gastrin signaling pathway; Head and neck squamous cell carcinoma; Thyroid hormones production and peripheral downstream signaling effects; Cytoplasmic ribosomal proteins; EGFR tyrosine kinase inhibitor resistance; IL-2 signaling pathway; Pleural mesothelioma; 2q37 copy number variation syndrome; A network map of Macrophage-stimulating protein (MSP) signaling; Interferon type I signaling pathways"	"47"	"0"	"1659.2"	"1724.0"	"5332.0"	"1563.1"	"1518.2"	"1340.6"	"6347.5"	"623.3"	"1068.2"	"768.4"	"672.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13428"	"Treacle protein OS=Homo sapiens OX=9606 GN=TCOF1 PE=1 SV=3"	"10"	"15"	"27"	"15"	"1488"	"152.0"	"9.04"	"6114.79"	"34.47"	"15"	"10"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf03546"	"6949"	"ENSG00000070814"	"TCOF1"	"A0JLU0; B4E111; hsa:6949; Q13428; Q6SC72; Q7Z5W9; Q96A52; Q99408; Q99860"	""	""	"0"	"0"	"1203.5"	"1270.8"	"3821.9"	"1157.7"	"1087.3"	"1200.3"	"7441.6"	"1847.8"	"1389.7"	"1260.6"	"1337.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P12081"	"Histidine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=HARS1 PE=1 SV=2"	"23"	"13"	"21"	"11"	"509"	"57.4"	"5.88"	"3445.98"	"34.40"	"11"	"10"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00458, Pf03129, Pf13393"	"3035"	"ENSG00000170445"	"HARS1"	"B4DHQ1; B4DY73; D6REN6; hsa:3035; J3KNE5; P12081"	"Cytosolic tRNA aminoacylation"	"Allograft rejection"	"2"	"2"	"579.2"	"688.3"	"2393.3"	"650.4"	"535.0"	"416.6"	"2525.1"	"507.8"	"1488.2"	"2714.2"	"4659.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46779"	"60S ribosomal protein L28 OS=Homo sapiens OX=9606 GN=RPL28 PE=1 SV=3"	"42"	"9"	"31"	"9"	"137"	"15.7"	"12.02"	"5436.07"	"34.39"	"9"	"7"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01778"	"6158"	"ENSG00000108107"	"RPL28"	"B2R4A6; B4DEP9; C9JB50; E9PB24; G5E9L2; hsa:6158; P46779; Q6IAY0; Q96FX1; Q9BWQ0"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"1864.6"	"2006.0"	"6350.8"	"1917.7"	"1606.8"	"1460.2"	"7122.5"	"657.1"	"1080.1"	"765.0"	"756.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q00341"	"Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2"	"11"	"11"	"20"	"11"	"1268"	"141.4"	"6.87"	"3289.36"	"34.25"	"9"	"11"	"other metabolic processes;transport"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013"	"3069"	"ENSG00000115677"	"HDLBP"	"B4DTQ2; E7EM71; hsa:3069; Q00341; Q53QU2; Q9UCY3"	"HDL clearance"	"2q37 copy number variation syndrome"	"2"	"0"	"567.5"	"615.4"	"2044.2"	"588.1"	"516.3"	"417.4"	"1982.7"	"282.9"	"394.3"	"327.9"	"351.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96C36"	"Pyrroline-5-carboxylate reductase 2 OS=Homo sapiens OX=9606 GN=PYCR2 PE=1 SV=1"	"33"	"8"	"16"	"7"	"320"	"33.6"	"7.77"	"3294.87"	"34.25"	"7"	"7"	"other metabolic processes;stress response"	"mitochondrion"	"other molecular function"	"Pf03807, Pf14748"	"29920"	"ENSG00000143811"	"PYCR2"	"A8K798; hsa:29920; Q7Z515; Q96C36; Q9Y5J4"	"Glutamate and glutamine metabolism"	"Metabolic reprogramming in colon cancer"	"2"	"1"	"627.6"	"645.4"	"1699.5"	"669.3"	"667.5"	"613.6"	"1859.0"	"247.6"	"456.1"	"340.3"	"273.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05141"	"ADP/ATP translocase 2 OS=Homo sapiens OX=9606 GN=SLC25A5 PE=1 SV=7"	"48"	"14"	"28"	"6"	"298"	"32.8"	"9.69"	"6131.99"	"34.23"	"13"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytoskeleton;mitochondrion"	"transporter activity;other molecular function"	"Pf00153"	"292"	"ENSG00000005022"	"SLC25A5"	"B2RCV1; hsa:292; O43350; P05141"	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane; Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization"	"Electron transport chain: OXPHOS system in mitochondria; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"5"	"8"	"2521.7"	"2565.3"	"10274.7"	"2322.4"	"1849.0"	"1533.3"	"8324.5"	"712.5"	"1144.4"	"826.9"	"912.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9ULP9"	"TBC1 domain family member 24 OS=Homo sapiens OX=9606 GN=TBC1D24 PE=1 SV=2"	"18"	"9"	"18"	"9"	"559"	"62.9"	"7.36"	"2825.16"	"34.19"	"7"	"9"	"cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;other cell component"	"enzyme regulator activity"	"Pf00566, Pf07534"	"57465"	"ENSG00000162065"	"TBC1D24"	"A0JNW3; B9A6M6; hsa:57465; Q2KJ08; Q9ULP9"	"TBC/RABGAPs"	""	"1"	"0"	"288.1"	"296.3"	"880.2"	"295.3"	"341.7"	"239.5"	"936.3"	"292.4"	"1713.7"	"2687.9"	"3189.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14866"	"Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2"	"16"	"7"	"16"	"6"	"589"	"64.1"	"8.22"	"2826.99"	"33.90"	"5"	"7"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf11835, Pf13893"	"3191"	"ENSG00000104824; ENSG00000282947"	"HNRNPL"	"A6ND69; A6NIT8; hsa:3191; P14866; Q9H3P3"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"mRNA processing; Hippocampal synaptogenesis and neurogenesis; 11p11.2 copy number variation syndrome"	"5"	"1"	"901.8"	"910.5"	"2461.2"	"949.5"	"854.4"	"734.3"	"2798.4"	"527.3"	"814.6"	"614.6"	"701.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14314"	"Glucosidase 2 subunit beta OS=Homo sapiens OX=9606 GN=PRKCSH PE=1 SV=2"	"20"	"12"	"19"	"12"	"528"	"59.4"	"4.41"	"3758.02"	"33.84"	"10"	"9"	"protein metabolism;other metabolic processes;developmental processes;signal transduction"	"ER/Golgi;other cell component"	"other molecular function"	"Pf12999, Pf13015, Pf13202"	"5589"	"ENSG00000130175"	"PRKCSH"	"A8K318; hsa:5589; P14314; Q96BU9; Q96D06; Q9P0W9"	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Advanced glycosylation endproduct receptor signaling; Maturation of spike protein; Calnexin/calreticulin cycle; Maturation of spike protein"	""	"7"	"0"	"889.7"	"1423.3"	"5602.6"	"1575.1"	"1381.7"	"1328.4"	"9092.6"	"907.9"	"1438.4"	"1016.6"	"1049.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62280"	"40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3"	"54"	"12"	"21"	"12"	"158"	"18.4"	"10.30"	"4149.52"	"33.81"	"10"	"9"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00366, Pf16205"	"6205"	"ENSG00000142534"	"RPS11"	"B2R4F5; hsa:6205; P04643; P62280; Q498Y6; Q6IRY0"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"VEGFA-VEGFR2 signaling; IL-18 signaling pathway; Cytoplasmic ribosomal proteins"	"21"	"0"	"2262.3"	"2284.0"	"6809.9"	"2077.5"	"1933.0"	"1666.1"	"7442.8"	"812.1"	"1257.3"	"984.2"	"919.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96CT7"	"Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1"	"45"	"10"	"21"	"10"	"223"	"25.8"	"9.54"	"3563.18"	"33.69"	"9"	"9"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf06244"	"115098"	"ENSG00000007080"	"CCDC124"	"hsa:115098; Q96CT7"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"957.7"	"1046.3"	"2586.6"	"944.4"	"962.3"	"869.9"	"3588.4"	"812.1"	"1157.4"	"987.7"	"1215.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12931"	"Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3"	"19"	"11"	"21"	"10"	"704"	"80.1"	"8.21"	"3804.98"	"33.50"	"10"	"10"	"other biological processes"	"other membranes;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00183, Pf02518"	"10131"	"ENSG00000126602"	"TRAP1"	"B4DR68; D3DUC8; F5H897; hsa:10131; O43642; O75235; Q12931; Q9UHL5"	"Respiratory electron transport"	"TNF-alpha signaling pathway; Clock-controlled autophagy in bone metabolism"	"3"	"0"	"526.6"	"921.0"	"2984.3"	"868.7"	"749.2"	"682.8"	"2464.9"	"293.0"	"404.1"	"367.8"	"387.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P36542"	"ATP synthase subunit gamma, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1C PE=1 SV=1"	"33"	"10"	"23"	"10"	"298"	"33.0"	"9.22"	"3266.01"	"33.33"	"10"	"9"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf00231"	"509"	"ENSG00000165629"	"ATP5F1C"	"A8KA31; hsa:509; P36542; Q5VYP3; Q6I9V2; Q96AS8"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"Electron transport chain: OXPHOS system in mitochondria"	"3"	"0"	"1014.2"	"1046.4"	"3827.2"	"928.5"	"746.8"	"615.0"	"3456.8"	"402.0"	"587.3"	"490.3"	"528.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62191"	"26S proteasome regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMC1 PE=1 SV=1"	"32"	"14"	"25"	"12"	"440"	"49.2"	"6.21"	"4829.25"	"33.29"	"13"	"10"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf16450, Pf17862"	"5700"	"ENSG00000100764"	"PSMC1"	"B4DR63; hsa:5700; P49014; P62191; Q03527; Q6IAW0; Q6NW36; Q96AZ3"	"Regulation of expression of SLITs and ROBOs; N-glycan trimming in the ER and Calnexin/Calreticulin cycle; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"64"	"0"	"1649.2"	"1703.2"	"5331.1"	"1597.5"	"1439.4"	"1175.8"	"5299.0"	"787.5"	"1176.4"	"1067.8"	"1169.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P15880"	"40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2"	"43"	"13"	"24"	"13"	"293"	"31.3"	"10.24"	"5250.83"	"33.29"	"11"	"10"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00333, Pf03719"	"6187"	"ENSG00000140988"	"RPS2"	"B2R5G0; D3DU82; hsa:6187; P15880; Q3MIB1"	"Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; RMTs methylate histone arginines; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Protein methylation; Peptide chain elongation; rRNA modification in the nucleus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"22"	"0"	"2387.0"	"2586.0"	"8342.4"	"2017.5"	"1809.1"	"1626.2"	"8364.3"	"818.2"	"1281.0"	"1010.7"	"1044.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q08J23"	"RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2"	"17"	"8"	"13"	"8"	"767"	"86.4"	"6.77"	"2250.21"	"33.27"	"5"	"7"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytoskeleton;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01189"	"54888"	"ENSG00000037474"	"NSUN2"	"A8K529; B2RNR4; B3KP09; B4DQW2; G3V1R4; hsa:54888; Q08J23; Q9BVN4; Q9H858; Q9NXD9"	"tRNA modification in the nucleus and cytosol"	""	"1"	"0"	"291.3"	"350.6"	"1210.0"	"319.6"	"313.8"	"244.9"	"1357.5"	"137.6"	"191.3"	"155.7"	"172.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15056"	"Eukaryotic translation initiation factor 4H OS=Homo sapiens OX=9606 GN=EIF4H PE=1 SV=5"	"44"	"7"	"13"	"7"	"248"	"27.4"	"7.23"	"1936.53"	"33.13"	"4"	"7"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"7458"	"ENSG00000106682"	"EIF4H"	"A8K3R1; D3DXF6; D3DXF8; hsa:7458; Q15056"	"L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Translation initiation complex formation; Ribosomal scanning and start codon recognition"	"Translation factors; 7q11.23 copy number variation syndrome"	"7"	"0"	"329.5"	"427.0"	"1531.0"	"384.3"	"326.4"	"273.9"	"2113.3"	"307.0"	"386.8"	"305.7"	"289.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61221"	"ATP-binding cassette sub-family E member 1 OS=Homo sapiens OX=9606 GN=ABCE1 PE=1 SV=1"	"16"	"8"	"18"	"8"	"599"	"67.3"	"8.34"	"4047.07"	"32.97"	"8"	"8"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;mitochondrion;translational apparatus;other cell component"	"enzyme regulator activity;translation activity;other molecular function"	"Pf00005, Pf00037, Pf04068"	"6059"	"ENSG00000164163"	"ABCE1"	"hsa:6059; O88793; P61221; Q13181; Q13864; Q6NR76; Q96AL0; Q96B10; Q99K66"	"OAS antiviral response; Interferon alpha/beta signaling"	""	"2"	"0"	"499.4"	"462.2"	"1478.6"	"483.7"	"470.9"	"409.4"	"1818.2"	"351.2"	"584.8"	"613.3"	"725.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P27695"	"DNA-(apurinic or apyrimidinic site) lyase OS=Homo sapiens OX=9606 GN=APEX1 PE=1 SV=2"	"39"	"9"	"18"	"9"	"318"	"35.5"	"8.12"	"4644.34"	"32.95"	"9"	"7"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytoskeleton;mitochondrion;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03372"	"328"	"ENSG00000100823"	"APEX1"	"hsa:328; P27695; Q969L5; Q99775"	"Displacement of DNA glycosylase by APEX1; POLB-Dependent Long Patch Base Excision Repair; PCNA-Dependent Long Patch Base Excision Repair; Abasic sugar-phosphate removal via the single-nucleotide replacement pathway"	"Thyroid stimulating hormone (TSH) signaling pathway; Spinal cord injury; Base excision repair; DNA repair pathways, full network"	"10"	"0"	"365.3"	"382.2"	"1308.5"	"382.3"	"340.4"	"224.0"	"2417.1"	"606.3"	"845.6"	"758.9"	"1069.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q00688"	"Peptidyl-prolyl cis-trans isomerase FKBP3 OS=Homo sapiens OX=9606 GN=FKBP3 PE=1 SV=1"	"40"	"14"	"23"	"14"	"224"	"25.2"	"9.28"	"4454.01"	"32.91"	"13"	"10"	""	"nucleus"	"other molecular function"	"Pf00254, Pf18410"	"2287"	"ENSG00000100442"	"FKBP3"	"B2R4Q9; hsa:2287; Q00688; Q14317"	""	""	"0"	"0"	"1785.4"	"1755.5"	"5206.4"	"1798.3"	"1225.8"	"1079.1"	"6102.4"	"1254.1"	"2544.6"	"3519.1"	"4984.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UMS4"	"Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1"	"18"	"8"	"19"	"8"	"504"	"55.1"	"6.61"	"2818.82"	"32.89"	"7"	"8"	"cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00400, Pf04564, Pf08606"	"27339"	"ENSG00000110107"	"PRPF19"	"hsa:27339; Q9UMS4"	"Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; mRNA Splicing - Major Pathway; Formation of TC-NER Pre-Incision Complex"	""	"5"	"0"	"827.3"	"899.2"	"3592.1"	"908.4"	"789.4"	"619.8"	"3677.3"	"542.7"	"1017.9"	"1188.3"	"2099.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30419"	"Glycylpeptide N-tetradecanoyltransferase 1 OS=Homo sapiens OX=9606 GN=NMT1 PE=1 SV=2"	"24"	"9"	"18"	"7"	"496"	"56.8"	"7.80"	"3105.65"	"32.86"	"7"	"8"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf01233, Pf02799"	"4836"	"ENSG00000136448"	"NMT1"	"A8K7C1; hsa:4836; P30419; Q9UE09"	"Inactivation, recovery and regulation of the phototransduction cascade; Late Phase of HIV Life Cycle; Activation, myristolyation of BID and translocation to mitochondria"	""	"3"	"2"	"560.0"	"596.4"	"1637.3"	"477.4"	"474.4"	"367.0"	"1865.8"	"357.2"	"624.5"	"816.7"	"1424.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46940"	"Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1"	"6"	"8"	"17"	"8"	"1657"	"189.1"	"6.48"	"3598.42"	"32.81"	"8"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00307, Pf00612, Pf00616, Pf03836"	"8826"	"ENSG00000140575"	"IQGAP1"	"A7MBM3; hsa:8826; P46940"	"Neutrophil degranulation; RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RHO GTPases activate IQGAPs; RAC2 GTPase cycle; RHOV GTPase cycle; Signaling by BRAF and RAF1 fusions; RHOU GTPase cycle; Nephrin family interactions; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants"	"VEGFA-VEGFR2 signaling; Ebola virus infection in host; Ciliary landscape; EGF/EGFR signaling pathway; Regulation of actin cytoskeleton; G13 signaling pathway"	"25"	"0"	"396.1"	"444.1"	"1555.7"	"382.2"	"383.3"	"313.7"	"1558.3"	"203.2"	"381.5"	"463.2"	"818.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99459"	"Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2"	"17"	"10"	"16"	"9"	"802"	"92.2"	"8.18"	"3059.00"	"32.81"	"8"	"8"	"cell cycle OR cell proliferation;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf11831, Pf13921"	"988"	"ENSG00000096401"	"CDC5L"	"hsa:988; Q76N46; Q99459; Q99974"	"mRNA Splicing - Major Pathway"	""	"1"	"1"	"343.8"	"366.3"	"1113.6"	"324.8"	"309.0"	"228.5"	"1254.0"	"204.9"	"341.2"	"356.2"	"590.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P258"	"Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2"	"21"	"12"	"24"	"12"	"522"	"56.0"	"8.78"	"5191.98"	"32.71"	"12"	"8"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00415"	"55920"	"ENSG00000179051; ENSG00000281540"	"RCC2"	"hsa:55920; Q8IVL9; Q9BSN6; Q9NPV8; Q9P258"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	""	"6"	"0"	"1553.1"	"1628.1"	"4220.2"	"1306.7"	"1100.9"	"1071.3"	"4461.1"	"979.7"	"1176.0"	"1054.1"	"1105.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q07065"	"Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2"	"23"	"12"	"22"	"12"	"602"	"66.0"	"5.92"	"4041.58"	"32.69"	"12"	"10"	""	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	""	""	"10970"	"ENSG00000136026"	"CKAP4"	"hsa:10970; Q07065; Q504S5; Q53ES6"	"Neutrophil degranulation; RND2 GTPase cycle; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; RND3 GTPase cycle; Surfactant metabolism"	""	"6"	"0"	"843.7"	"877.3"	"2861.3"	"789.7"	"791.9"	"612.6"	"2876.6"	"362.2"	"547.1"	"438.6"	"423.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P17980"	"26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3 PE=1 SV=3"	"29"	"9"	"20"	"9"	"439"	"49.2"	"5.24"	"5074.81"	"32.60"	"9"	"7"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf16450, Pf17862"	"5702"	"ENSG00000165916"	"PSMC3"	"B2R8V1; hsa:5702; P17980; Q3B757; Q3B865; Q53HU5; Q6GPG8; Q6IBS1; Q96HD3"	"Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Neutrophil degranulation; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; UCH proteinases; Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of expression of SLITs and ROBOs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"64"	"0"	"1018.4"	"1086.6"	"3605.5"	"1006.4"	"896.0"	"770.0"	"4003.5"	"562.9"	"807.5"	"644.2"	"658.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30041"	"Peroxiredoxin-6 OS=Homo sapiens OX=9606 GN=PRDX6 PE=1 SV=3"	"47"	"12"	"21"	"12"	"224"	"25.0"	"6.38"	"3965.59"	"32.60"	"11"	"10"	"other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00578, Pf10417"	"9588"	"ENSG00000117592"	"PRDX6"	"A8JZY7; hsa:9588; P30041; P32077; Q5TAH4; Q5ZEZ8"	"Detoxification of Reactive Oxygen Species; Neutrophil degranulation"	"Nuclear receptors meta-pathway; NRF2 pathway; VEGFA-VEGFR2 signaling"	"5"	"0"	"673.8"	"870.2"	"4413.7"	"797.1"	"700.9"	"520.8"	"4837.0"	"455.1"	"546.6"	"423.4"	"370.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y606"	"tRNA pseudouridine synthase A OS=Homo sapiens OX=9606 GN=PUS1 PE=1 SV=3"	"26"	"9"	"19"	"9"	"427"	"47.4"	"8.41"	"3585.38"	"32.48"	"9"	"9"	"RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01416"	"80324"	"ENSG00000177192"	"PUS1"	"A8K877; B3KQC1; hsa:80324; Q8WYT2; Q9BU44; Q9Y606"	""	""	"0"	"0"	"344.1"	"328.8"	"934.0"	"372.7"	"334.8"	"247.3"	"1012.7"	"294.8"	"789.2"	"1735.1"	"2862.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46781"	"40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3"	"51"	"14"	"29"	"14"	"194"	"22.6"	"10.65"	"6566.82"	"32.47"	"13"	"11"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00163, Pf01479"	"6203"	"ENSG00000170889; ENSG00000274005; ENSG00000274626; ENSG00000274646; ENSG00000274950; ENSG00000275323; ENSG00000277079; ENSG00000277359; ENSG00000278081; ENSG00000278270"	"RPS9"	"A9C4C1; hsa:6203; P46781; Q4QRK7; Q9BVZ0"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"20"	"0"	"1903.0"	"2112.1"	"7650.2"	"2031.0"	"1760.6"	"1554.9"	"6726.4"	"692.3"	"996.3"	"777.4"	"773.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P83731"	"60S ribosomal protein L24 OS=Homo sapiens OX=9606 GN=RPL24 PE=1 SV=1"	"43"	"10"	"26"	"10"	"157"	"17.8"	"11.25"	"6269.73"	"32.43"	"10"	"6"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01246"	"6152"	"ENSG00000114391"	"RPL24"	"B2R4Y3; hsa:6152; P38663; P83731; Q6IBS3"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"2654.4"	"2744.6"	"7744.8"	"2466.7"	"2358.4"	"1984.4"	"8941.5"	"895.4"	"1504.8"	"1003.4"	"843.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P12694"	"2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=BCKDHA PE=1 SV=2"	"26"	"10"	"18"	"10"	"445"	"50.4"	"8.27"	"3480.08"	"32.28"	"9"	"9"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00676"	"593"	"ENSG00000248098"	"BCKDHA"	"B4DP47; E7EW46; hsa:593; P12694; Q16034; Q16472"	"Glyoxylate metabolism and glycine degradation; Branched-chain amino acid catabolism"	"Lipid metabolism pathway"	"3"	"0"	"705.6"	"719.9"	"1448.9"	"686.8"	"698.8"	"615.6"	"1433.6"	"360.4"	"531.3"	"410.6"	"424.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05387"	"60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1"	"75"	"6"	"15"	"5"	"115"	"11.7"	"4.54"	"3136.61"	"32.16"	"5"	"5"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf00428"	"6181"	"ENSG00000177600"	"RPLP2"	"hsa:6181; P05387; Q6FG96"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins; Opioid receptor pathways"	"16"	"1"	"546.4"	"582.5"	"2509.3"	"557.2"	"497.5"	"383.1"	"2078.0"	"176.6"	"231.5"	"170.1"	"178.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06737"	"Glycogen phosphorylase, liver form OS=Homo sapiens OX=9606 GN=PYGL PE=1 SV=4"	"12"	"9"	"18"	"7"	"847"	"97.1"	"7.17"	"3294.60"	"32.12"	"8"	"8"	"other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;other cell component"	"other molecular function"	"Pf00343"	"5836"	"ENSG00000100504"	"PYGL"	"A6NDQ4; B4DUB7; F5H816; hsa:5836; O60567; O60752; O60913; P06737; Q501V9; Q641R5; Q96G82"	"Neutrophil degranulation; Glycogen breakdown (glycogenolysis)"	"TNF-alpha signaling pathway; Glycogen synthesis and degradation; Disorders of galactose metabolism"	"5"	"2"	"389.4"	"504.1"	"1799.7"	"418.9"	"398.3"	"310.7"	"2480.5"	"310.9"	"438.2"	"377.9"	"360.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13347"	"Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens OX=9606 GN=EIF3I PE=1 SV=1"	"30"	"10"	"20"	"10"	"325"	"36.5"	"5.64"	"4079.75"	"32.11"	"10"	"8"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf00400"	"8668"	"ENSG00000084623"	"EIF3I"	"hsa:8668; Q13347"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"8"	"0"	"1156.3"	"1219.8"	"3531.3"	"1005.4"	"967.0"	"841.9"	"3665.2"	"520.5"	"779.7"	"725.3"	"745.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P29966"	"Myristoylated alanine-rich C-kinase substrate OS=Homo sapiens OX=9606 GN=MARCKS PE=1 SV=4"	"22"	"7"	"19"	"7"	"332"	"31.5"	"4.45"	"3672.05"	"32.07"	"7"	"7"	"cell organization and biogenesis;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02063"	"4082"	"ENSG00000277443"	"MARCKS"	"E1P560; hsa:4082; P29966; Q2LA83; Q5TDB7"	"Acetylcholine regulates insulin secretion"	"Brain-derived neurotrophic factor (BDNF) signaling pathway"	"2"	"0"	"944.9"	"1121.2"	"3525.9"	"1007.7"	"924.6"	"813.9"	"4942.7"	"746.1"	"1014.0"	"809.4"	"754.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P54136"	"Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2"	"15"	"9"	"19"	"9"	"660"	"75.3"	"6.68"	"4134.15"	"32.02"	"9"	"9"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00750, Pf03485, Pf05746"	"5917"	"ENSG00000113643"	"RARS1"	"B2RBS9; hsa:5917; P54136; Q53GY4; Q9BWA1"	"Cytosolic tRNA aminoacylation; Selenoamino acid metabolism"	"Amino acid metabolism"	"3"	"0"	"513.1"	"558.5"	"2433.7"	"499.0"	"386.8"	"276.9"	"2338.6"	"207.6"	"377.1"	"546.5"	"1231.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P10515"	"Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3"	"15"	"9"	"17"	"9"	"647"	"69.0"	"7.84"	"2730.17"	"32.00"	"7"	"8"	"other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf00198, Pf00364, Pf02817"	"1737"	"ENSG00000150768"	"DLAT"	"hsa:1737; P10515; Q16783; Q53EP3"	"Glyoxylate metabolism and glycine degradation; Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Neuroinflammation and glutamatergic signaling; Glycolysis and gluconeogenesis"	"7"	"0"	"1737.4"	"1750.9"	"3443.5"	"2145.6"	"1652.1"	"1765.1"	"2546.2"	"458.5"	"821.5"	"684.3"	"905.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96CW1"	"AP-2 complex subunit mu OS=Homo sapiens OX=9606 GN=AP2M1 PE=1 SV=2"	"22"	"7"	"15"	"7"	"435"	"49.6"	"9.54"	"2945.08"	"31.98"	"5"	"6"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00928, Pf01217"	"1173"	"ENSG00000161203"	"AP2M1"	"A6NE12; D3DNT1; hsa:1173; P20172; P53679; Q96CW1"	"Potential therapeutics for SARS; Cargo recognition for clathrin-mediated endocytosis; VLDLR internalisation and degradation; Recycling pathway of L1; MHC class II antigen presentation; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; LDL clearance; Nef Mediated CD4 Down-regulation; Retrograde neurotrophin signalling; Nef Mediated CD8 Down-regulation; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; Nef mediated downregulation of CD28 cell surface expression; Formation of annular gap junctions"	"Synaptic vesicle pathway; GABA receptor signaling; EGF/EGFR signaling pathway; Fragile X syndrome; GDNF signaling"	"21"	"0"	"335.7"	"344.4"	"1108.4"	"332.4"	"324.6"	"291.9"	"1204.6"	"515.4"	"1229.7"	"1580.3"	"2036.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14203"	"Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3"	"11"	"11"	"18"	"11"	"1278"	"141.6"	"5.81"	"2905.32"	"31.97"	"8"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01302, Pf12455"	"1639"	"ENSG00000204843"	"DCTN1"	"A8MY36; B4DM45; E9PFS5; E9PGE1; G5E9H4; hsa:1639; O95296; Q14203; Q6IQ37; Q9BRM9; Q9UIU1; Q9UIU2"	"MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Signaling by ALK fusions and activated point mutants; XBP1(S) activates chaperone genes"	""	"6"	"0"	"443.6"	"418.3"	"1522.6"	"449.2"	"420.5"	"324.7"	"1744.7"	"202.6"	"292.9"	"265.5"	"240.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q09028"	"Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3"	"23"	"9"	"15"	"4"	"425"	"47.6"	"4.89"	"2256.83"	"31.97"	"6"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400, Pf12265"	"5928"	"ENSG00000162521"	"RBBP4"	"B2R6G9; B4DRH0; D3DPQ3; hsa:5928; P31149; Q09028; Q53H02; Q96BV9"	"RNA Polymerase I Transcription Initiation; Potential therapeutics for SARS; HCMV Early Events; Deposition of new CENPA-containing nucleosomes at the centromere; Oxidative Stress Induced Senescence; HDACs deacetylate histones; Activation of anterior HOX genes in hindbrain development during early embryogenesis; PRC2 methylates histones and DNA; Defective pyroptosis; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6; PKMTs methylate histone lysines; G1/S-Specific Transcription; Regulation of TP53 Activity through Acetylation; Polo-like kinase mediated events; Cyclin E associated events during G1/S transition ; Transcription of E2F targets under negative control by DREAM complex; Cyclin A:Cdk2-associated events at S phase entry; Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"	"Retinoblastoma gene in cancer; Interactome of polycomb repressive complex 2 (PRC2) ; Tumor suppressor activity of SMARCB1; Epithelial to mesenchymal transition in colorectal cancer; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; Pleural mesothelioma; DYRK1A involvement regarding cell proliferation in brain development"	"28"	"5"	"835.4"	"1122.3"	"3213.3"	"973.8"	"962.3"	"827.2"	"3974.0"	"872.6"	"1162.4"	"885.3"	"885.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14240"	"Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2"	"27"	"11"	"22"	"1"	"407"	"46.4"	"5.48"	"4422.24"	"31.85"	"10"	"8"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"1974"	"ENSG00000156976"	"EIF4A2"	"D3DNU9; hsa:1974; Q14240; Q53XJ6; Q96B90; Q96EA8"	"L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Deadenylation of mRNA; ISG15 antiviral mechanism; Translation initiation complex formation; Ribosomal scanning and start codon recognition"	"Translation factors; Translation inhibitors in chronically activated PDGFRA cells"	"9"	"0"	"105.9"	"106.5"	"284.2"	"115.7"	"123.8"	"104.4"	"321.1"	"100.4"	"136.8"	"104.4"	"102.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46063"	"ATP-dependent DNA helicase Q1 OS=Homo sapiens OX=9606 GN=RECQL PE=1 SV=3"	"16"	"8"	"17"	"8"	"649"	"73.4"	"7.88"	"3071.80"	"31.78"	"7"	"8"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf16124"	"5965"	"ENSG00000004700"	"RECQL"	"A8K6G2; hsa:5965; P46063"	""	"Progeria-associated lipodystrophy"	"1"	"0"	"636.8"	"671.3"	"1797.3"	"633.8"	"548.3"	"478.3"	"1675.0"	"269.9"	"388.1"	"323.7"	"371.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75533"	"Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3"	"10"	"11"	"20"	"11"	"1304"	"145.7"	"7.09"	"3915.94"	"31.77"	"11"	"9"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf08920"	"23451"	"ENSG00000115524"	"SF3B1"	"E9PCH3; hsa:23451; O75533"	"B-WICH complex positively regulates rRNA expression; mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"mRNA processing"	"4"	"0"	"561.7"	"625.2"	"1998.9"	"654.8"	"604.9"	"541.4"	"2006.6"	"232.1"	"432.3"	"312.1"	"309.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BSJ8"	"Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1"	"6"	"5"	"10"	"5"	"1104"	"122.8"	"5.83"	"1980.98"	"31.60"	"3"	"5"	"cell organization and biogenesis;transport"	"plasma membrane;other membranes;ER/Golgi"	"transporter activity;other molecular function"	"Pf00168, Pf17047"	"23344"	"ENSG00000139641"	"ESYT1"	"A0FGR7; A8K2S2; hsa:23344; O94848; Q6PJN4; Q9BSJ8; Q9H6J1; Q9H6W2; Q9Y416"	"RHOG GTPase cycle; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; Glycosphingolipid metabolism; RHOD GTPase cycle; RHOF GTPase cycle"	""	"7"	"0"	"196.1"	"215.6"	"757.9"	"278.9"	"467.4"	"732.3"	"1185.6"	"491.2"	"820.9"	"676.8"	"733.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P41250"	"Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3"	"21"	"11"	"17"	"10"	"739"	"83.1"	"7.03"	"3121.00"	"31.57"	"9"	"8"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"non-structural extracellular;cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00458, Pf00587, Pf03129"	"2617"	"ENSG00000106105"	"GARS1"	"A0A090N8G0; B3KQA2; B4DIA0; hsa:2617; P41250; Q969Y1"	"Cytosolic tRNA aminoacylation; Mitochondrial tRNA aminoacylation"	""	"2"	"1"	"647.0"	"656.7"	"3270.3"	"753.3"	"504.5"	"387.1"	"3608.9"	"371.7"	"570.9"	"425.4"	"402.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P18859"	"ATP synthase-coupling factor 6, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PF PE=1 SV=1"	"43"	"5"	"10"	"5"	"108"	"12.6"	"9.52"	"1590.74"	"31.40"	"3"	"5"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf05511"	"522"	"ENSG00000154723"	"ATP5PF"	"hsa:522; J3KQ83; P18859"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"Electron transport chain: OXPHOS system in mitochondria; Oxidative phosphorylation"	"4"	"0"	"358.6"	"570.0"	"1583.9"	"513.1"	"537.3"	"532.0"	"1778.2"	"448.0"	"703.1"	"507.8"	"562.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P37802"	"Transgelin-2 OS=Homo sapiens OX=9606 GN=TAGLN2 PE=1 SV=3"	"65"	"9"	"15"	"9"	"199"	"22.4"	"8.25"	"2963.64"	"31.35"	"7"	"8"	"cell organization and biogenesis;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton"	"cytoskeletal activity"	"Pf00307, Pf00402"	"8407"	"ENSG00000158710"	"TAGLN2"	"E9KL39; hsa:8407; P37802; Q5JRQ6; Q5JRQ7; Q6FGI1; Q9BUH5; Q9H4P0"	"Platelet degranulation"	""	"1"	"0"	"249.1"	"308.5"	"1718.7"	"348.8"	"328.4"	"194.0"	"3294.1"	"184.8"	"328.1"	"231.9"	"164.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P42167"	"Lamina-associated polypeptide 2, isoforms beta/gamma OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2"	"26"	"10"	"16"	"10"	"454"	"50.6"	"9.38"	"2932.49"	"31.32"	"8"	"8"	""	"other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03020, Pf08198"	"7112"	"ENSG00000120802"	"TMPO"	"A2T926; hsa:7112; P42167; Q14861"	"RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOG GTPase cycle; RHOD GTPase cycle; RHOJ GTPase cycle; RHOF GTPase cycle"	"Envelope proteins and their potential roles in EDMD physiopathology; Overlap between signal transduction pathways contributing to LMNA laminopathies"	"12"	"0"	"968.2"	"1015.9"	"3402.8"	"930.1"	"877.5"	"685.8"	"3978.9"	"589.3"	"895.2"	"666.2"	"672.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15185"	"Prostaglandin E synthase 3 OS=Homo sapiens OX=9606 GN=PTGES3 PE=1 SV=1"	"51"	"8"	"17"	"8"	"160"	"18.7"	"4.54"	"4105.32"	"31.25"	"8"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf04969"	"10728"	"ENSG00000110958"	"PTGES3"	"A8K7D0; B4DHP2; B4DP11; B4DP21; hsa:10728; Q15185; Q8WU70"	"Estrogen-dependent gene expression; Potential therapeutics for SARS; HSF1 activation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Aryl hydrocarbon receptor signalling; Synthesis of Prostaglandins (PG) and Thromboxanes (TX); Attenuation phase"	"Aryl hydrocarbon receptor pathway; Glucocorticoid receptor pathway; Nuclear receptors meta-pathway"	"11"	"0"	"676.6"	"963.6"	"4298.3"	"1053.3"	"978.4"	"928.7"	"7531.3"	"838.2"	"1067.3"	"730.2"	"655.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q04695"	"Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2"	"16"	"9"	"24"	"2"	"432"	"48.1"	"5.02"	"3717.57"	"31.15"	"9"	"8"	"cell organization and biogenesis;other biological processes"	"plasma membrane;cytosol;cytoskeleton"	"other molecular function"	"Pf00038"	"3872"	"ENSG00000128422"	"KRT17"	"A5Z1M9; A5Z1N0; A5Z1N1; A5Z1N2; A6NDV6; A6NKQ2; hsa:3872; Q04695; Q6IP98; Q8N1P6"	"Formation of the cornified envelope"	"1p36 copy number variation syndrome; Pancreatic cancer subtypes"	"4"	"0"	"1342.4"	"197.7"	"277.6"	"212.7"	"84.1"	"76.7"	"256.9"	"63.6"	"73.7"	"58.0"	"73.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q02543"	"60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2"	"48"	"10"	"20"	"10"	"176"	"20.7"	"10.71"	"3523.51"	"31.14"	"9"	"9"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01775"	"6142"	"ENSG00000105640"	"RPL18A"	"hsa:6142; Q02543"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"15"	"0"	"2122.7"	"2186.0"	"6558.3"	"1979.3"	"1915.3"	"1787.1"	"6735.0"	"716.4"	"1167.4"	"821.4"	"695.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46776"	"60S ribosomal protein L27a OS=Homo sapiens OX=9606 GN=RPL27A PE=1 SV=2"	"34"	"7"	"19"	"7"	"148"	"16.6"	"11.00"	"3631.31"	"31.13"	"7"	"6"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;other cell component"	"other molecular function"	"Pf00828"	"6157"	"ENSG00000166441"	"RPL27A"	"B2R4B3; hsa:6157; P46776"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"1662.9"	"1805.8"	"5087.6"	"1528.1"	"1487.9"	"1263.2"	"5603.1"	"556.0"	"956.5"	"567.7"	"559.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P53582"	"Methionine aminopeptidase 1 OS=Homo sapiens OX=9606 GN=METAP1 PE=1 SV=2"	"26"	"7"	"10"	"7"	"386"	"43.2"	"7.17"	"1698.85"	"31.02"	"3"	"7"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00557, Pf15801"	"23173"	"ENSG00000164024"	"METAP1"	"B4E2E6; hsa:23173; P53582"	"Inactivation, recovery and regulation of the phototransduction cascade"	""	"1"	"0"	"204.5"	"238.6"	"487.2"	"239.9"	"205.5"	"202.3"	"631.6"	"179.7"	"427.5"	"642.7"	"1172.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15020"	"Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1"	"14"	"11"	"18"	"11"	"963"	"109.9"	"5.57"	"2993.62"	"30.97"	"9"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00076, Pf05391, Pf16605"	"9733"	"ENSG00000075856"	"SART3"	"A8K2E4; B7ZKM0; hsa:9733; Q15020; Q2M2H0; Q58F06; Q8IUS1; Q96J95"	""	""	"0"	"0"	"787.0"	"845.4"	"2354.2"	"826.0"	"817.7"	"673.3"	"3393.4"	"541.0"	"794.4"	"635.9"	"620.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61160"	"Actin-related protein 2 OS=Homo sapiens OX=9606 GN=ACTR2 PE=1 SV=1"	"21"	"6"	"12"	"5"	"394"	"44.7"	"6.74"	"1529.14"	"30.97"	"4"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00022"	"10097"	"ENSG00000138071"	"ACTR2"	"B2RCP5; D6W5F4; E9PF41; hsa:10097; O15142; P61160; Q96C82"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Neutrophil degranulation; Clathrin-mediated endocytosis; EPHB-mediated forward signaling"	"Physico-chemical features and toxicity-associated pathways; Embryonic stem cell pluripotency pathways"	"8"	"0"	"193.1"	"186.7"	"690.0"	"187.7"	"172.3"	"135.1"	"676.3"	"166.2"	"319.5"	"574.4"	"921.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95202"	"Mitochondrial proton/calcium exchanger protein OS=Homo sapiens OX=9606 GN=LETM1 PE=1 SV=1"	"16"	"10"	"16"	"10"	"739"	"83.3"	"6.70"	"2457.14"	"30.95"	"7"	"9"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;translation activity;other molecular function"	"Pf07766"	"3954"	"ENSG00000168924"	"LETM1"	"B4DED2; hsa:3954; O95202; Q9UF65"	"RHOG GTPase cycle; Mitochondrial calcium ion transport"	""	"2"	"0"	"688.4"	"686.3"	"2677.9"	"705.4"	"648.2"	"525.0"	"2833.1"	"325.9"	"563.6"	"403.9"	"400.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y265"	"RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1 PE=1 SV=1"	"23"	"8"	"17"	"8"	"456"	"50.2"	"6.42"	"3747.82"	"30.83"	"8"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf06068, Pf17856"	"8607"	"ENSG00000175792; ENSG00000284901"	"RUVBL1"	"B2R5S0; hsa:8607; P82276; Q1KMR0; Q53HK5; Q53HL7; Q53Y27; Q9BSX9; Q9Y265"	"Ub-specific processing proteases; DNA Damage Recognition in GG-NER; UCH proteinases; Deposition of new CENPA-containing nucleosomes at the centromere; Formation of the beta-catenin:TCF transactivating complex; Telomere Extension By Telomerase; HATs acetylate histones"	"Gastric cancer network 1; lncRNA in canonical Wnt signaling and colorectal cancer"	"9"	"0"	"808.6"	"826.6"	"3411.7"	"739.2"	"647.0"	"449.0"	"2869.5"	"235.0"	"335.8"	"245.8"	"247.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62857"	"40S ribosomal protein S28 OS=Homo sapiens OX=9606 GN=RPS28 PE=1 SV=1"	"68"	"6"	"19"	"6"	"69"	"7.8"	"10.70"	"4290.97"	"30.83"	"6"	"6"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01200"	"6234"	"ENSG00000233927"	"RPS28"	"hsa:6234; P25112; P62857"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"896.0"	"970.8"	"2857.8"	"879.2"	"788.6"	"668.9"	"3098.8"	"375.6"	"570.7"	"413.6"	"427.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95602"	"DNA-directed RNA polymerase I subunit RPA1 OS=Homo sapiens OX=9606 GN=POLR1A PE=1 SV=2"	"8"	"9"	"15"	"9"	"1720"	"194.7"	"7.03"	"3106.49"	"30.82"	"7"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00623, Pf04983, Pf04997, Pf04998, Pf05000"	"25885"	"ENSG00000068654"	"POLR1A"	"B7Z7T0; D6W5M0; hsa:25885; O95602; Q0VG05; Q9UEH0; Q9UFT9"	"B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"Pyrimidine metabolism; Eukaryotic transcription initiation; 2q13 copy number variation syndrome"	"8"	"0"	"130.5"	"129.0"	"488.9"	"131.1"	"141.5"	"108.4"	"554.0"	"179.5"	"884.7"	"920.9"	"917.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P12268"	"Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2"	"20"	"10"	"19"	"10"	"514"	"55.8"	"6.90"	"5018.52"	"30.80"	"10"	"8"	"cell cycle OR cell proliferation;other metabolic processes;developmental processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00478, Pf00571"	"3615"	"ENSG00000178035"	"IMPDH2"	"hsa:3615; P12268; Q6LEF3"	"Potential therapeutics for SARS; Neutrophil degranulation; Purine ribonucleoside monophosphate biosynthesis; Azathioprine ADME"	"Rett syndrome causing genes"	"5"	"0"	"927.7"	"983.3"	"4674.1"	"880.5"	"717.4"	"484.8"	"5383.9"	"420.7"	"565.6"	"441.1"	"431.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43143"	"Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2"	"14"	"9"	"16"	"9"	"795"	"90.9"	"7.46"	"2577.63"	"30.75"	"7"	"8"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"1665"	"ENSG00000109606"	"DHX15"	"hsa:1665; O43143; Q9NQT7"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"0"	"226.7"	"242.7"	"799.2"	"263.4"	"264.3"	"234.0"	"1128.5"	"154.8"	"242.9"	"206.3"	"163.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P37837"	"Transaldolase OS=Homo sapiens OX=9606 GN=TALDO1 PE=1 SV=2"	"23"	"9"	"20"	"9"	"337"	"37.5"	"6.81"	"3400.62"	"30.69"	"8"	"8"	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00923"	"6888"	"ENSG00000177156"	"TALDO1"	"B2R8M2; hsa:6888; O00751; P37837; Q8WV32; Q8WZ45"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; NFE2L2 regulates pentose phosphate pathway genes; Pentose phosphate pathway; Insulin effects increased synthesis of Xylulose-5-Phosphate; TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P; TALDO1 deficiency: failed conversion of  Fru(6)P, E4P to SH7P, GA3P"	"Pentose phosphate metabolism; Cori cycle; Metabolic reprogramming in colon cancer"	"9"	"0"	"880.1"	"1030.9"	"4534.5"	"875.8"	"809.0"	"559.5"	"5727.7"	"589.6"	"699.9"	"538.8"	"488.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BRG1"	"Vacuolar protein-sorting-associated protein 25 OS=Homo sapiens OX=9606 GN=VPS25 PE=1 SV=1"	"48"	"8"	"16"	"8"	"176"	"20.7"	"6.34"	"4498.36"	"30.53"	"8"	"6"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf05871"	"84313"	"ENSG00000131475"	"VPS25"	"B2R581; hsa:84313; Q9BRG1"	"Endosomal Sorting Complex Required For Transport (ESCRT); HCMV Late Events"	""	"2"	"0"	"291.6"	"285.7"	"904.4"	"258.5"	"252.4"	"209.6"	"1213.8"	"449.9"	"1318.7"	"1947.5"	"2469.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62979"	"Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2"	"51"	"10"	"19"	"10"	"156"	"18.0"	"9.64"	"3408.47"	"30.50"	"8"	"7"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;translational apparatus;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00240, Pf01599"	"6233"	"ENSG00000143947"	"RPS27A"	"hsa:6233; P02248; P02249; P02250; P14798; P62979; P62988; Q29120; Q6LBL4; Q6LDU5; Q8WYN8; Q91887; Q91888; Q9BQ77; Q9BWD6; Q9BX98; Q9UEF2; Q9UEG1; Q9UEK8; Q9UPK7"	"Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Aggrephagy; ISG15 antiviral mechanism; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; Orc1 removal from chromatin; Assembly of the pre-replicative complex; Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; Recognition of DNA damage by PCNA-containing replication complex; Dual Incision in GG-NER; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER; Cargo recognition for clathrin-mediated endocytosis; EGFR downregulation; Negative regulation of MET activity; InlB-mediated entry of Listeria monocytogenes into host cell; Antigen processing: Ubiquitination & Proteasome degradation; Regulation of PTEN stability and activity; Downregulation of ERBB4 signaling; Regulation of PTEN localization; Degradation of GLI1 by the proteasome; Hedgehog 'on' state; Activated NOTCH1 Transmits Signal to the Nucleus; FCERI mediated NF-kB activation; Downstream TCR signaling; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Neddylation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Regulation of PLK1 Activity at G2/M Transition; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery; E3 ubiquitin ligases ubiquitinate target proteins; Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Stimuli-sensing channels; Amyloid fiber formation; Fanconi Anemia Pathway; Budding and maturation of HIV virion; Membrane binding and targetting of GAG proteins; Endosomal Sorting Complex Required For Transport (ESCRT); Late endosomal microautophagy; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; NOTCH2 Activation and Transmission of Signal to the Nucleus; NOTCH3 Activation and Transmission of Signal to the Nucleus; Peroxisomal protein import; Regulation of TP53 Degradation; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Activation of IRF3, IRF7 mediated by TBK1, IKBKE; IKK complex recruitment mediated by RIP1; TRAF6-mediated induction of TAK1 complex within TLR4 complex; IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation; ER Quality Control Compartment (ERQC); SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Deactivation of the beta-catenin transactivating complex; Oxidative Stress Induced Senescence; Circadian Clock; Regulation of signaling by CBL; Metalloprotease DUBs; Regulation of necroptotic cell death; Oncogene Induced Senescence; Cyclin D associated events in G1; APC/C:Cdc20 mediated degradation of Cyclin B; APC-Cdc20 mediated degradation of Nek2A; Senescence-Associated Secretory Phenotype (SASP); Negative regulation of FLT3; Downregulation of ERBB2:ERBB3 signaling; Interferon alpha/beta signaling; Inactivation of CSF3 (G-CSF) signaling; JNK (c-Jun kinases) phosphorylation and  activation mediated by activated human TAK1; Regulation of TP53 Activity through Methylation; Regulation of BACH1 activity; NOD1/2 Signaling Pathway; TICAM1, RIP1-mediated IKK complex recruitment; p75NTR recruits signalling complexes; NF-kB is activated and signals survival; TAK1-dependent IKK and NF-kappa-B activation  ; Regulation of TNFR1 signaling; TNFR1-induced NF-kappa-B signaling pathway; MAP3K8 (TPL2)-dependent MAPK1/3 activation; IRAK1 recruits IKK complex; IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation; Regulation of NF-kappa B signaling; Negative regulators of DDX58/IFIH1 signaling; Prevention of phagosomal-lysosomal fusion; Downregulation of TGF-beta receptor signaling; Downregulation of SMAD2/3:SMAD4 transcriptional activity; Signaling by CSF1 (M-CSF) in myeloid cells; NOTCH1 Intracellular Domain Regulates Transcription; TICAM1-dependent activation of IRF3/IRF7; TICAM1,TRAF6-dependent induction of TAK1 complex; Glycogen synthesis; Formation of TC-NER Pre-Incision Complex; Modulation by Mtb of host immune system; activated TAK1 mediates p38 MAPK activation; IRAK2 mediated activation of TAK1 complex; SARS-CoV-1 activates/modulates innate immune responses; Alpha-protein kinase 1 signaling pathway; Ovarian tumor domain proteases; Spry regulation of FGF signaling; RAS processing; PINK1-PRKN Mediated Mitophagy; Josephin domain DUBs; Regulation of FZD by ubiquitination; Chaperone Mediated Autophagy; InlA-mediated entry of Listeria monocytogenes into host cells; Formation of Incision Complex in GG-NER; Iron uptake and transport; VLDLR internalisation and degradation; Myoclonic epilepsy of Lafora; DNA Damage Recognition in GG-NER; Negative regulation of MAPK pathway; TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition); NRIF signals cell death from the nucleus; Assembly Of The HIV Virion; Regulation of innate immune responses to cytosolic DNA; N-glycan trimming in the ER and Calnexin/Calreticulin cycle; PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1; Pexophagy; Maturation of protein E; Maturation of protein E; FLT3 signaling by CBL mutants; TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling"	"Cytoplasmic ribosomal proteins"	"201"	"0"	"2251.0"	"2737.0"	"7252.5"	"2198.0"	"2021.4"	"1653.7"	"7724.5"	"1717.9"	"2089.3"	"1513.7"	"1848.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13200"	"26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3"	"13"	"9"	"17"	"9"	"908"	"100.1"	"5.20"	"3052.85"	"30.45"	"8"	"9"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf01851, Pf17781, Pf18051"	"5708"	"ENSG00000175166"	"PSMD2"	"B4DX07; B4DXY1; E7EW34; E9PCS3; hsa:5708; Q12932; Q13200; Q15321; Q53XQ4; Q96I12"	"Neutrophil degranulation; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; TNF-alpha signaling pathway; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"65"	"0"	"453.0"	"483.4"	"1505.8"	"427.2"	"438.2"	"342.0"	"1338.0"	"272.3"	"283.7"	"289.8"	"422.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62917"	"60S ribosomal protein L8 OS=Homo sapiens OX=9606 GN=RPL8 PE=1 SV=2"	"38"	"10"	"18"	"10"	"257"	"28.0"	"11.03"	"2919.11"	"30.29"	"9"	"9"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00181, Pf03947"	"6132"	"ENSG00000161016"	"RPL8"	"A8K094; D3DWN2; hsa:6132; P25120; P62917; Q567Q7; Q969V7; Q9BWQ9"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"1784.3"	"2002.6"	"5731.5"	"1598.1"	"1520.4"	"1342.5"	"7646.9"	"752.9"	"1068.6"	"719.7"	"620.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P40925"	"Malate dehydrogenase, cytoplasmic OS=Homo sapiens OX=9606 GN=MDH1 PE=1 SV=4"	"39"	"13"	"23"	"13"	"334"	"36.4"	"7.36"	"4426.74"	"30.20"	"12"	"10"	"other metabolic processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00056, Pf02866"	"4190"	"ENSG00000014641"	"MDH1"	"B2R5V5; B4DUN2; B7Z3I7; F5H098; hsa:4190; P40925; Q6I9V0"	"Gluconeogenesis"	"Sterol regulatory element-binding proteins (SREBP) signaling; TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Clear cell renal cell carcinoma pathways; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; TCA cycle in senescence; Glycolysis and gluconeogenesis"	"8"	"0"	"1093.9"	"1379.8"	"6987.9"	"1496.5"	"1060.5"	"826.0"	"9964.7"	"844.4"	"977.4"	"719.3"	"582.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14744"	"Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4"	"15"	"10"	"19"	"10"	"637"	"72.6"	"6.29"	"3495.54"	"30.09"	"9"	"8"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05185, Pf17285, Pf17286"	"10419"	"ENSG00000100462"	"PRMT5"	"A8MTP3; A8MZ91; B4DX49; B4DY30; B5BU10; D3DS33; E2QRE7; hsa:10419; O14744; Q6IBR1; Q9UKH1"	"snRNP Assembly; RMTs methylate histone arginines; Regulation of TP53 Activity through Methylation"	"Transcription co-factors SKI and SKIL protein partners; Nitric oxide metabolism in cystic fibrosis"	"5"	"0"	"850.4"	"1023.4"	"3626.0"	"959.7"	"877.0"	"761.4"	"4809.4"	"675.9"	"840.1"	"684.8"	"744.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30153"	"Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4"	"13"	"8"	"19"	"8"	"589"	"65.3"	"5.11"	"4286.65"	"30.01"	"8"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02985"	"5518"	"ENSG00000105568"	"PPP2R1A"	"hsa:5518; P30153; Q13773; Q6ICQ3; Q96DH3"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Cyclin A/B1/B2 associated events during G2/M transition; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Negative regulation of MAPK pathway; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Regulation of TP53 Degradation; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Cyclin D associated events in G1; Disassembly of the destruction complex and recruitment of AXIN to the membrane; RAF activation; Beta-catenin phosphorylation cascade; Signaling by GSK3beta mutants; CTNNB1 S33 mutants aren't phosphorylated; CTNNB1 S37 mutants aren't phosphorylated; CTNNB1 S45 mutants aren't phosphorylated; CTNNB1 T41 mutants aren't phosphorylated; APC truncation mutants have impaired AXIN binding; AXIN missense mutants destabilize the destruction complex; Truncations of AMER1 destabilize the destruction complex; Spry regulation of FGF signaling; MASTL Facilitates Mitotic Progression; Regulation of glycolysis by fructose 2,6-bisphosphate metabolism; Initiation of Nuclear Envelope (NE) Reformation; Platelet sensitization by LDL; CTLA4 inhibitory signaling; Inhibition of replication initiation of damaged DNA by RB1/E2F1; DARPP-32 events; PP2A-mediated dephosphorylation of key metabolic factors; ERKs are inactivated"	"Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Wnt signaling pathway and pluripotency; PI3K-Akt signaling pathway; 16p11.2 proximal deletion syndrome; Glycogen synthesis and degradation; Cohesin complex - Cornelia de Lange syndrome"	"49"	"0"	"479.9"	"623.2"	"2336.1"	"632.9"	"572.7"	"571.1"	"2559.4"	"372.2"	"580.7"	"501.3"	"527.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31930"	"Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3"	"21"	"7"	"14"	"7"	"480"	"52.6"	"6.37"	"2321.31"	"30.01"	"5"	"7"	"other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00675, Pf05193"	"7384"	"ENSG00000010256"	"UQCRC1"	"B2R7R8; hsa:7384; P31930; Q96DD2"	"Respiratory electron transport"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex III assembly"	"4"	"0"	"316.8"	"378.5"	"1590.7"	"421.3"	"377.6"	"314.5"	"1929.0"	"174.5"	"276.7"	"232.1"	"215.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HCC0"	"Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC2 PE=1 SV=1"	"23"	"10"	"20"	"10"	"563"	"61.3"	"7.68"	"4120.33"	"29.79"	"9"	"8"	"other metabolic processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf01039"	"64087"	"ENSG00000131844"	"MCCC2"	"A6NIY9; hsa:64087; Q96C27; Q9HCC0; Q9Y4L7"	"Biotin transport and metabolism; Branched-chain amino acid catabolism; Defective HLCS causes multiple carboxylase deficiency"	""	"3"	"0"	"932.0"	"971.4"	"1817.8"	"871.3"	"910.6"	"854.7"	"2991.9"	"1045.2"	"1604.6"	"1278.9"	"1333.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q05682"	"Caldesmon OS=Homo sapiens OX=9606 GN=CALD1 PE=1 SV=3"	"13"	"10"	"19"	"10"	"793"	"93.2"	"5.66"	"3250.87"	"29.64"	"9"	"9"	"cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton"	"cytoskeletal activity;other molecular function"	"Pf02029"	"800"	"ENSG00000122786"	"CALD1"	"A8K0X1; hsa:800; Q05682; Q13978; Q13979; Q14741; Q14742; Q9UD91"	"Smooth Muscle Contraction"	"Myometrial relaxation and contraction pathways"	"2"	"0"	"1034.9"	"993.1"	"2487.9"	"1004.0"	"1033.5"	"905.9"	"3523.5"	"951.1"	"1521.1"	"1227.5"	"1107.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P00492"	"Hypoxanthine-guanine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=HPRT1 PE=1 SV=2"	"53"	"10"	"20"	"10"	"218"	"24.6"	"6.68"	"3381.71"	"29.64"	"9"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;developmental processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00156"	"3251"	"ENSG00000165704"	"HPRT1"	"A6NHF0; B2R8M9; hsa:3251; P00492"	"Azathioprine ADME; Purine salvage; Defective HPRT1 disrupts guanine and hypoxanthine salvage"	"Mesodermal commitment pathway"	"4"	"0"	"582.3"	"667.0"	"3473.9"	"696.5"	"591.1"	"469.9"	"3957.0"	"293.7"	"497.6"	"353.4"	"332.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31939"	"Bifunctional purine biosynthesis protein PURH OS=Homo sapiens OX=9606 GN=ATIC PE=1 SV=3"	"22"	"9"	"15"	"9"	"592"	"64.6"	"6.71"	"1960.90"	"29.56"	"6"	"9"	"other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol"	"other molecular function"	"Pf01808, Pf02142"	"471"	"ENSG00000138363"	"ATIC"	"A8K202; E9PBU3; hsa:471; P31939; Q13856; Q53S28"	"Signaling by ALK fusions and activated point mutants; Purine ribonucleoside monophosphate biosynthesis"	"One-carbon metabolism"	"3"	"0"	"412.5"	"524.3"	"2065.9"	"432.1"	"383.6"	"273.1"	"2718.2"	"264.9"	"315.7"	"254.3"	"249.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50914"	"60S ribosomal protein L14 OS=Homo sapiens OX=9606 GN=RPL14 PE=1 SV=4"	"37"	"11"	"21"	"11"	"215"	"23.4"	"10.93"	"3637.21"	"29.55"	"10"	"8"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01929"	"9045"	"ENSG00000188846"	"RPL14"	"hsa:9045; P50914; Q45RF0; Q53G20; Q8TBD5; Q8WUT0; Q92579; Q96GR0; Q9BSB8; Q9BW65; Q9BYF6"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"1981.7"	"2164.5"	"6213.1"	"1877.8"	"1938.5"	"1566.8"	"8313.9"	"753.1"	"1215.4"	"862.6"	"798.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P33993"	"DNA replication licensing factor MCM7 OS=Homo sapiens OX=9606 GN=MCM7 PE=1 SV=4"	"15"	"10"	"20"	"10"	"719"	"81.3"	"6.46"	"4652.78"	"29.50"	"10"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf14551, Pf17207, Pf17855"	"4176"	"ENSG00000166508"	"MCM7"	"A4D2A1; A4D2A2; E9PGN9; hsa:4176; P33993; Q15076; Q96D34; Q96GL1"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"miRNA regulation of DNA damage response; Cell cycle; Retinoblastoma gene in cancer; Ciliary landscape; G1 to S cell cycle control; DNA replication; 10q11.21q11.23 copy number variation syndrome"	"13"	"0"	"679.3"	"733.3"	"2826.4"	"709.2"	"629.9"	"467.4"	"3232.3"	"331.6"	"473.2"	"367.7"	"374.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43242"	"26S proteasome non-ATPase regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PSMD3 PE=1 SV=2"	"20"	"9"	"16"	"9"	"534"	"60.9"	"8.44"	"2697.67"	"29.41"	"8"	"8"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf01399, Pf08375"	"5709"	"ENSG00000108344"	"PSMD3"	"B3KMW9; B4DT72; hsa:5709; O43242; Q96EI2; Q9BQA4"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"64"	"0"	"709.9"	"667.0"	"1883.7"	"566.9"	"491.4"	"433.0"	"1661.3"	"267.9"	"389.9"	"341.5"	"357.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43390"	"Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1"	"19"	"12"	"20"	"5"	"633"	"70.9"	"8.13"	"3829.03"	"29.40"	"10"	"10"	"RNA metabolism OR transcription;other metabolic processes"	"ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf18360"	"10236"	"ENSG00000125944; ENSG00000282958"	"HNRNPR"	"hsa:10236; O43390; Q2L7G6; Q5TEH1; Q9BV64; S4R3J4"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"mRNA processing"	"3"	"0"	"360.0"	"355.4"	"1147.6"	"362.4"	"325.5"	"306.2"	"1231.6"	"154.2"	"240.4"	"214.8"	"156.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15029"	"116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1"	"11"	"8"	"17"	"6"	"972"	"109.4"	"5.00"	"2811.94"	"29.35"	"7"	"8"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf00679, Pf03144, Pf03764, Pf14492, Pf16004"	"9343"	"ENSG00000108883"	"EFTUD2"	"B4DK30; B4DMC0; D3DX58; hsa:9343; K7EJ81; Q15029; Q9BUR0"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"mRNA processing; Ciliary landscape"	"4"	"0"	"392.7"	"442.8"	"1624.2"	"423.6"	"387.6"	"308.6"	"1380.0"	"184.0"	"273.0"	"210.6"	"177.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q93009"	"Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2"	"8"	"6"	"14"	"6"	"1102"	"128.2"	"5.55"	"3467.82"	"29.30"	"6"	"6"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00443, Pf00917, Pf12436, Pf14533"	"7874"	"ENSG00000187555"	"USP7"	"A6NMY8; B7Z815; H0Y3G8; hsa:7874; Q93009"	"Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Regulation of TP53 Degradation; Ub-specific processing proteases; Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Formation of TC-NER Pre-Incision Complex; Regulation of PTEN localization"	"Nucleotide excision repair in xeroderma pigmentosum"	"9"	"0"	"294.8"	"384.8"	"1120.9"	"360.7"	"335.6"	"277.9"	"966.9"	"152.8"	"246.4"	"210.2"	"190.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99729"	"Heterogeneous nuclear ribonucleoprotein A/B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2"	"29"	"10"	"20"	"9"	"332"	"36.2"	"8.21"	"3622.04"	"29.28"	"9"	"8"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08143"	"3182"	"ENSG00000197451"	"HNRNPAB"	"B3KNN5; D3DWP7; hsa:3182; Q04150; Q8N7U3; Q99729; Q9BQ99"	""	"Pre-implantation embryo; mRNA processing"	"2"	"0"	"867.9"	"961.4"	"2639.5"	"896.4"	"848.8"	"723.7"	"3569.6"	"591.9"	"914.5"	"668.6"	"708.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62333"	"26S proteasome regulatory subunit 10B OS=Homo sapiens OX=9606 GN=PSMC6 PE=1 SV=1"	"28"	"11"	"20"	"11"	"389"	"44.1"	"7.49"	"3977.26"	"29.13"	"11"	"9"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf16450, Pf17862"	"5706"	"ENSG00000100519"	"PSMC6"	"B2R975; hsa:5706; P49719; P62333; Q6IBU3; Q92524"	"The role of GTSE1 in G2/M progression after G2 checkpoint; Separation of Sister Chromatids; Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; SARS-CoV-1 targets host intracellular signalling and regulatory pathways"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Ciliary landscape; Alzheimer's disease"	"65"	"0"	"729.1"	"693.9"	"2644.7"	"755.7"	"760.9"	"571.2"	"2784.6"	"372.8"	"527.3"	"452.6"	"496.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14979"	"Heterogeneous nuclear ribonucleoprotein D-like OS=Homo sapiens OX=9606 GN=HNRNPDL PE=1 SV=3"	"23"	"8"	"19"	"6"	"420"	"46.4"	"9.57"	"3679.91"	"29.01"	"8"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity"	"Pf00076"	"9987"	"ENSG00000152795"	"HNRNPDL"	"hsa:9987; O14979; Q6SPF2; Q7KZ74; Q7KZ75; Q96IM0; Q96S43"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	""	"1"	"0"	"311.3"	"344.5"	"1032.9"	"351.4"	"339.5"	"300.7"	"1087.0"	"217.2"	"378.3"	"360.9"	"506.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P43686"	"26S proteasome regulatory subunit 6B OS=Homo sapiens OX=9606 GN=PSMC4 PE=1 SV=2"	"32"	"9"	"16"	"8"	"418"	"47.3"	"5.21"	"3159.94"	"28.94"	"7"	"7"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf16450, Pf17862"	"5704"	"ENSG00000013275; ENSG00000281221"	"PSMC4"	"hsa:5704; P43686; Q96FV5; Q9UBM3; Q9UEX3"	"Neddylation; KEAP1-NFE2L2 pathway; Regulation of RAS by GAPs; Regulation of expression of SLITs and ROBOs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Interleukin-1 signaling; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Ciliary landscape; Alzheimer's disease"	"64"	"0"	"362.0"	"290.9"	"975.4"	"270.3"	"243.2"	"186.8"	"967.9"	"130.0"	"168.7"	"151.5"	"139.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11310"	"Medium-chain specific acyl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ACADM PE=1 SV=1"	"24"	"6"	"12"	"6"	"421"	"46.6"	"8.37"	"2665.28"	"28.91"	"5"	"5"	"other metabolic processes;stress response;developmental processes;other biological processes"	"other membranes;mitochondrion;other cell component"	"other molecular function"	"Pf00441, Pf02770, Pf02771"	"34"	"ENSG00000117054"	"ACADM"	"hsa:34; P11310; Q5T4U4; Q9NYF1"	"PPARA activates gene expression; mitochondrial fatty acid beta-oxidation of unsaturated fatty acids; Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA"	"Fatty acid beta-oxidation; PPAR-alpha pathway; Nuclear receptors meta-pathway; Mitochondrial long chain fatty acid beta-oxidation; Amino acid metabolism; PPAR signaling pathway; Mitochondrial fatty acid oxidation disorders; Female steroid hormones in cardiomyocyte energy metabolism; Sudden infant death syndrome (SIDS) susceptibility pathways"	"13"	"0"	"215.7"	"226.6"	"866.3"	"236.0"	"205.5"	"154.1"	"857.2"	"117.8"	"177.8"	"137.4"	"148.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08243"	"Asparagine synthetase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=ASNS PE=1 SV=4"	"20"	"11"	"18"	"11"	"561"	"64.3"	"6.86"	"2806.26"	"28.75"	"8"	"10"	"other metabolic processes;stress response;other biological processes"	"cytosol"	"other molecular function"	"Pf00733, Pf13537"	"440"	"ENSG00000070669"	"ASNS"	"A4D1I8; B4DXZ1; B7ZAA9; D6W5R3; E9PCI3; E9PCX6; hsa:440; P08184; P08243; Q15666; Q549T9; Q96HD0"	"Aspartate and asparagine metabolism; Response of EIF2AK1 (HRI) to heme deficiency; ATF4 activates genes in response to endoplasmic reticulum  stress; Response of EIF2AK4 (GCN2) to amino acid deficiency"	"Photodynamic therapy-induced unfolded protein response; Amino acid metabolism"	"6"	"0"	"923.0"	"804.8"	"3713.8"	"841.7"	"652.8"	"486.3"	"4237.8"	"408.2"	"537.6"	"415.4"	"393.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P43487"	"Ran-specific GTPase-activating protein OS=Homo sapiens OX=9606 GN=RANBP1 PE=1 SV=1"	"43"	"8"	"15"	"8"	"201"	"23.3"	"5.29"	"1753.26"	"28.72"	"5"	"8"	"transport;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00638"	"5902"	"ENSG00000099901"	"RANBP1"	"hsa:5902; P43487; Q53EY3"	"Rev-mediated nuclear export of HIV RNA"	"22q11.2 copy number variation syndrome"	"2"	"0"	"974.5"	"1259.9"	"4577.8"	"1552.4"	"1204.4"	"1016.4"	"4954.9"	"624.0"	"1005.4"	"676.5"	"631.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q07021"	"Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1"	"34"	"7"	"15"	"7"	"282"	"31.3"	"4.84"	"2970.92"	"28.71"	"6"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;translation activity;nucleic acid binding activity;other molecular function"	"Pf02330"	"708"	"ENSG00000108561"	"C1QBP"	"hsa:708; Q07021; Q2HXR8; Q9NNY8"	"RHOC GTPase cycle; RHOA GTPase cycle; Intrinsic Pathway of Fibrin Clot Formation; Apoptotic factor-mediated response; Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function"	"Complement system; Mesodermal commitment pathway; Ebola virus infection in host"	"8"	"0"	"745.0"	"865.9"	"2863.8"	"957.4"	"821.4"	"636.5"	"3574.4"	"565.9"	"787.1"	"646.0"	"599.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P43490"	"Nicotinamide phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=NAMPT PE=1 SV=1"	"21"	"8"	"15"	"8"	"491"	"55.5"	"7.15"	"2546.53"	"28.63"	"7"	"8"	"cell-cell signaling;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf04095, Pf18127"	"10135"	"ENSG00000105835"	"NAMPT"	"A4D0Q9; A4D0R0; hsa:10135; P43490; Q3KQV0; Q8WW95"	"NPAS4 regulates expression of target genes; BMAL1:CLOCK,NPAS2 activates circadian gene expression; Nicotinamide salvaging"	"Adipogenesis; NAD metabolism, sirtuins and aging; NAD+ metabolism; NAD+ biosynthetic pathways; Caloric restriction and aging; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence"	"9"	"0"	"400.7"	"754.1"	"2252.2"	"743.3"	"691.3"	"591.2"	"2116.9"	"270.0"	"438.3"	"488.3"	"749.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86UE4"	"Protein LYRIC OS=Homo sapiens OX=9606 GN=MTDH PE=1 SV=2"	"15"	"7"	"16"	"7"	"582"	"63.8"	"9.32"	"3282.54"	"28.60"	"7"	"7"	"RNA metabolism OR transcription;signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf15686"	"92140"	"ENSG00000147649"	"MTDH"	"hsa:92140; Q05DH2; Q52QU9; Q6PK07; Q86UE4; Q8TCX3"	""	"Gastric cancer network 2; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; CCL18 signaling pathway"	"3"	"0"	"470.1"	"500.7"	"1449.5"	"461.6"	"429.4"	"363.8"	"1777.8"	"360.3"	"698.2"	"849.6"	"1388.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62841"	"40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2"	"42"	"3"	"12"	"3"	"145"	"17.0"	"10.39"	"1776.34"	"28.56"	"1"	"3"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00203"	"6209"	"ENSG00000115268"	"RPS15"	"A5D8V9; hsa:6209; P11174; P62841; Q3KRA1; Q9UDC2"	"Regulation of expression of SLITs and ROBOs; SRP-dependent cotranslational protein targeting to membrane; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"752.8"	"775.4"	"2225.7"	"656.2"	"624.2"	"509.4"	"2086.6"	"183.6"	"334.4"	"215.6"	"222.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y262"	"Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1"	"20"	"10"	"18"	"10"	"564"	"66.7"	"6.34"	"3314.50"	"28.44"	"9"	"9"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity"	"Pf10255"	"51386"	"ENSG00000100129"	"EIF3L"	"B2RDG6; B4DYB2; G8JLH4; hsa:51386; Q53HQ1; Q53HT4; Q5QTR1; Q5TI15; Q6ICD2; Q9Y262"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition"	""	"6"	"0"	"827.6"	"856.9"	"2619.7"	"831.0"	"781.2"	"638.5"	"2516.7"	"328.0"	"536.3"	"470.7"	"517.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09972"	"Fructose-bisphosphate aldolase C OS=Homo sapiens OX=9606 GN=ALDOC PE=1 SV=2"	"26"	"10"	"16"	"2"	"364"	"39.4"	"6.87"	"2168.26"	"28.42"	"7"	"8"	"other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00274"	"230"	"ENSG00000109107"	"ALDOC"	"B2R5R3; hsa:230; P09972; Q3SYL3; Q6FH94; Q6P0L5"	"Neutrophil degranulation; Glycolysis; Gluconeogenesis"	"Clear cell renal cell carcinoma pathways; Glycolysis and gluconeogenesis"	"5"	"0"	"17.0"	"16.5"	"45.9"	"15.3"	"14.9"	"10.4"	"48.9"	"10.7"	"16.8"	"10.3"	"15.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55196"	"Afadin OS=Homo sapiens OX=9606 GN=AFDN PE=1 SV=3"	"5"	"7"	"15"	"7"	"1824"	"206.7"	"6.47"	"2637.42"	"28.36"	"6"	"7"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00498, Pf00595, Pf00788, Pf01843"	"4301"	"ENSG00000130396"	"AFDN"	"hsa:4301; O75087; O75088; O75089; P55196; Q59FP0; Q5TIG6; Q5TIG7; Q9NSN7; Q9NU92"	""	"VEGFA-VEGFR2 signaling; Ras signaling; 1q21.1 copy number variation syndrome"	"3"	"0"	"190.7"	"172.3"	"553.6"	"164.1"	"139.7"	"123.3"	"597.7"	"109.1"	"266.1"	"374.2"	"606.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12904"	"Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 OS=Homo sapiens OX=9606 GN=AIMP1 PE=1 SV=2"	"32"	"9"	"17"	"8"	"312"	"34.3"	"8.43"	"3403.59"	"28.22"	"9"	"8"	"cell-cell signaling;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf01588"	"9255"	"ENSG00000164022"	"AIMP1"	"B3KTR2; B4E1S7; hsa:9255; Q12904; Q6FG28; Q96CQ9"	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"Ciliary landscape"	"3"	"0"	"591.0"	"603.4"	"2307.6"	"520.4"	"497.1"	"369.2"	"2421.1"	"319.5"	"751.4"	"1025.4"	"1637.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60610"	"Protein diaphanous homolog 1 OS=Homo sapiens OX=9606 GN=DIAPH1 PE=1 SV=2"	"8"	"9"	"18"	"9"	"1272"	"141.3"	"5.41"	"3092.54"	"28.14"	"9"	"9"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf02181, Pf06346, Pf06367, Pf06371"	"1729"	"ENSG00000131504"	"DIAPH1"	"A6NF18; B7ZKW2; E9PEZ2; hsa:1729; O60610; Q17RN4; Q59FH8; Q9UC76"	"RHOC GTPase cycle; RHOA GTPase cycle; RHO GTPases Activate Formins; RHOB GTPase cycle; RHOD GTPase cycle; RHOF GTPase cycle; Neutrophil degranulation; ERBB2 Regulates Cell Motility"	"Microtubule cytoskeleton regulation; AGE/RAGE pathway; Focal adhesion; Type 2 papillary renal cell carcinoma; Regulation of actin cytoskeleton; G13 signaling pathway"	"14"	"0"	"443.3"	"846.9"	"2319.7"	"980.8"	"818.3"	"748.8"	"1908.9"	"313.2"	"498.6"	"472.0"	"509.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30086"	"Phosphatidylethanolamine-binding protein 1 OS=Homo sapiens OX=9606 GN=PEBP1 PE=1 SV=3"	"34"	"6"	"11"	"6"	"187"	"21.0"	"7.53"	"2225.14"	"28.00"	"4"	"5"	"other biological processes"	"cytosol"	"enzyme regulator activity;other molecular function"	"Pf01161"	"5037"	"ENSG00000089220"	"PEBP1"	"B2R4S1; hsa:5037; P30086"	"Signaling by BRAF and RAF1 fusions; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; MAP2K and MAPK activation; Negative regulation of MAPK pathway; Signaling by high-kinase activity BRAF mutants"	"Pancreatic adenocarcinoma pathway; EGF/EGFR signaling pathway"	"9"	"0"	"530.6"	"640.7"	"2942.5"	"644.7"	"588.3"	"399.9"	"3890.6"	"346.1"	"442.1"	"277.7"	"261.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P41091"	"Eukaryotic translation initiation factor 2 subunit 3 OS=Homo sapiens OX=9606 GN=EIF2S3 PE=1 SV=3"	"24"	"9"	"15"	"9"	"472"	"51.1"	"8.40"	"2740.61"	"27.95"	"6"	"9"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03144, Pf09173"	"1968"	"ENSG00000130741"	"EIF2S3"	"A0A024RBY4; A8K2Y2; B2R5N2; B5BTZ4; hsa:1968; P41091; Q53HK3"	"ABC-family proteins mediated transport; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK1 (HRI) to heme deficiency; PERK regulates gene expression; Recycling of eIF2:GDP; Response of EIF2AK4 (GCN2) to amino acid deficiency"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"12"	"0"	"1157.1"	"1244.8"	"4253.1"	"1211.4"	"941.2"	"875.4"	"3066.7"	"432.2"	"845.7"	"1271.1"	"2375.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P40939"	"Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2"	"14"	"9"	"17"	"9"	"763"	"82.9"	"9.04"	"2952.95"	"27.81"	"8"	"9"	"other metabolic processes;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf00378, Pf00725, Pf02737"	"3030"	"ENSG00000084754"	"HADHA"	"B2R7L4; B4DYP2; hsa:3030; P40939; Q16679; Q53T69; Q53TA2; Q96GT7; Q9UQC5"	"Acyl chain remodeling of CL; mitochondrial fatty acid beta-oxidation of unsaturated fatty acids; Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA; Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of myristoyl-CoA to lauroyl-CoA; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA; Beta oxidation of palmitoyl-CoA to myristoyl-CoA"	"Fatty acid beta-oxidation; Mitochondrial long chain fatty acid beta-oxidation; Valproic acid pathway; Mitochondrial fatty acid oxidation disorders; Sudden infant death syndrome (SIDS) susceptibility pathways"	"13"	"0"	"578.3"	"589.9"	"2079.0"	"544.5"	"463.5"	"362.7"	"1992.9"	"220.5"	"310.7"	"256.8"	"267.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14927"	"Cytochrome b-c1 complex subunit 7 OS=Homo sapiens OX=9606 GN=UQCRB PE=1 SV=2"	"53"	"6"	"16"	"6"	"111"	"13.5"	"8.78"	"3314.53"	"27.64"	"6"	"6"	"other metabolic processes;transport"	"other membranes;mitochondrion"	""	"Pf02271"	"7381"	"ENSG00000156467"	"UQCRB"	"E5RJU0; hsa:7381; P14927; Q6FGD1"	"Respiratory electron transport"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex III assembly; 11p11.2 copy number variation syndrome"	"5"	"0"	"341.0"	"461.6"	"1896.9"	"509.0"	"475.2"	"411.5"	"5157.9"	"1238.5"	"1803.4"	"1297.3"	"1485.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00425"	"Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2"	"14"	"7"	"16"	"6"	"579"	"63.7"	"8.87"	"3622.27"	"27.57"	"7"	"6"	"protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf00076"	"10643"	"ENSG00000136231"	"IGF2BP3"	"A0A4Z5; hsa:10643; O00425; Q63HM0; Q6MZZ2; Q86VB1"	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"	""	"1"	"0"	"346.9"	"338.3"	"1197.5"	"308.7"	"305.9"	"252.8"	"1364.7"	"149.2"	"215.7"	"171.4"	"177.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92747"	"Actin-related protein 2/3 complex subunit 1A OS=Homo sapiens OX=9606 GN=ARPC1A PE=2 SV=2"	"23"	"7"	"14"	"6"	"370"	"41.5"	"8.18"	"1960.68"	"27.50"	"5"	"7"	"cell organization and biogenesis"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf00400"	"10552"	"ENSG00000241685"	"ARPC1A"	"A4D276; B4DLQ7; D6W5S1; hsa:10552; Q7Z5U8; Q86WU5; Q8IXQ0; Q92747"	"Clathrin-mediated endocytosis; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; EPHB-mediated forward signaling"	"Pathogenic Escherichia coli infection"	"6"	"1"	"407.6"	"453.4"	"1591.7"	"402.6"	"261.5"	"221.7"	"1613.7"	"349.2"	"769.7"	"1820.3"	"3490.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14157"	"Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2"	"9"	"8"	"15"	"8"	"1087"	"114.5"	"7.11"	"2674.46"	"27.50"	"7"	"8"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	""	"Pf12478"	"9898"	"ENSG00000143569"	"UBAP2L"	"B4E0U8; hsa:9898; Q14157; Q5VU75; Q5VU76; Q9BTU3; Q9UGL2; Q9UGL3; Q9UGL4; Q9UGL5"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"716.2"	"717.9"	"2272.9"	"709.9"	"690.0"	"556.0"	"2700.7"	"462.0"	"683.5"	"506.5"	"490.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49411"	"Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2"	"24"	"10"	"19"	"10"	"452"	"49.5"	"7.61"	"4032.51"	"27.50"	"9"	"8"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"890.3"	"1163.0"	"4558.2"	"1176.3"	"978.8"	"768.5"	"5169.6"	"635.6"	"891.3"	"809.7"	"834.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62910"	"60S ribosomal protein L32 OS=Homo sapiens OX=9606 GN=RPL32 PE=1 SV=2"	"41"	"6"	"17"	"6"	"135"	"15.9"	"11.33"	"3604.45"	"27.47"	"6"	"5"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01655"	"6161"	"ENSG00000144713"	"RPL32"	"B2R4Q3; hsa:6161; P02433; P62910"	"SRP-dependent cotranslational protein targeting to membrane; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"1304.1"	"1509.7"	"3921.5"	"1157.6"	"1172.7"	"973.9"	"4228.8"	"453.1"	"711.9"	"472.3"	"429.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P48047"	"ATP synthase subunit O, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PO PE=1 SV=1"	"38"	"7"	"15"	"7"	"213"	"23.3"	"9.96"	"2578.72"	"27.46"	"6"	"7"	"other metabolic processes;transport"	"plasma membrane;other membranes;mitochondrion"	"transporter activity"	"Pf00213"	"539"	"ENSG00000241837"	"ATP5PO"	"B2R4E2; hsa:539; P48047; Q5U042; Q6IBI2"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"Electron transport chain: OXPHOS system in mitochondria; 7q11.23 copy number variation syndrome; Oxidative phosphorylation"	"5"	"0"	"1002.4"	"1004.9"	"4489.6"	"933.2"	"739.0"	"581.2"	"3472.6"	"267.4"	"464.7"	"355.1"	"424.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UQE7"	"Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2"	"8"	"8"	"16"	"8"	"1217"	"141.5"	"7.18"	"3042.79"	"27.46"	"8"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf02463, Pf06470"	"9126"	"ENSG00000108055"	"SMC3"	"A8K156; hsa:9126; O60464; Q5T482; Q9UQE7"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Meiotic synapsis; Estrogen-dependent gene expression; SUMOylation of DNA damage response and repair proteins; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"Cell cycle; Retinoblastoma gene in cancer; MECP2 and associated Rett syndrome; Prion disease pathway; Regulation of sister chromatid separation at the metaphase-anaphase transition; Cohesin complex - Cornelia de Lange syndrome; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome"	"14"	"0"	"435.3"	"475.1"	"1306.7"	"433.5"	"382.1"	"343.9"	"1121.3"	"176.4"	"273.2"	"230.6"	"289.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4L1"	"Hypoxia up-regulated protein 1 OS=Homo sapiens OX=9606 GN=HYOU1 PE=1 SV=1"	"14"	"9"	"13"	"9"	"999"	"111.3"	"5.22"	"2420.92"	"27.41"	"6"	"7"	"stress response;transport;other biological processes"	"non-structural extracellular;ER/Golgi;other cell component"	"other molecular function"	"Pf00012"	"10525"	"ENSG00000149428; ENSG00000280682"	"HYOU1"	"A8C1Z0; B7Z909; hsa:10525; Q2I204; Q53H25; Q9Y4L1"	"XBP1(S) activates chaperone genes; Scavenging by Class F Receptors"	"VEGFA-VEGFR2 signaling; 11p11.2 copy number variation syndrome"	"4"	"0"	"693.1"	"704.6"	"3011.1"	"657.5"	"600.3"	"393.2"	"3692.6"	"311.8"	"445.3"	"338.7"	"318.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P27797"	"Calreticulin OS=Homo sapiens OX=9606 GN=CALR PE=1 SV=1"	"24"	"9"	"16"	"9"	"417"	"48.1"	"4.44"	"2493.84"	"27.40"	"6"	"7"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;extracellular matrix;plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00262"	"811"	"ENSG00000179218"	"CALR"	"hsa:811; P27797; Q6IAT4; Q9UDG2"	"ER-Phagosome pathway; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Scavenging by Class A Receptors; Assembly of Viral Components at the Budding Site; Scavenging by Class F Receptors; ATF6 (ATF6-alpha) activates chaperone genes; Calnexin/calreticulin cycle"	"Androgen receptor signaling pathway; Complement system; Photodynamic therapy-induced unfolded protein response; VEGFA-VEGFR2 signaling; GDNF signaling; Calcium regulation in cardiac cells"	"13"	"0"	"699.8"	"966.4"	"4219.6"	"838.7"	"749.7"	"621.8"	"5601.0"	"549.1"	"800.7"	"572.6"	"536.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P00338"	"L-lactate dehydrogenase A chain OS=Homo sapiens OX=9606 GN=LDHA PE=1 SV=2"	"24"	"9"	"20"	"8"	"332"	"36.7"	"8.27"	"3676.27"	"27.32"	"9"	"8"	"other metabolic processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00056, Pf02866"	"3939"	"ENSG00000134333; ENSG00000288299"	"LDHA"	"B4DKQ2; B7Z5E3; D3DQY3; F8W819; hsa:3939; P00338; Q53G53; Q6IBM7; Q6ZNV1; Q9UDE8; Q9UDE9"	"Pyruvate metabolism"	"Cori cycle; HIF1A and PPARG regulation of glycolysis; Photodynamic therapy-induced HIF-1 survival signaling; VEGFA-VEGFR2 signaling; Amino acid metabolism; Clear cell renal cell carcinoma pathways; PI3K/AKT/mTOR - vitamin D3 signaling; Metabolic reprogramming in colon cancer; Aerobic glycolysis; Glycolysis in senescence; Orexin receptor pathway; CCL18 signaling pathway; Glucose metabolism in triple-negative breast cancer cells; Lactate shuttle in glial cells; Glycolysis and gluconeogenesis; A network map of Macrophage-stimulating protein (MSP) signaling"	"17"	"0"	"846.9"	"1010.0"	"4755.8"	"948.5"	"697.0"	"454.6"	"5234.2"	"441.2"	"484.7"	"365.5"	"290.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16576"	"Histone-binding protein RBBP7 OS=Homo sapiens OX=9606 GN=RBBP7 PE=1 SV=1"	"16"	"7"	"13"	"2"	"425"	"47.8"	"5.05"	"2292.92"	"27.21"	"4"	"7"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400, Pf12265"	"5931"	"ENSG00000102054"	"RBBP7"	"hsa:5931; Q16576; Q5JP00"	"HCMV Early Events; Deposition of new CENPA-containing nucleosomes at the centromere; Oxidative Stress Induced Senescence; HDACs deacetylate histones; Activation of anterior HOX genes in hindbrain development during early embryogenesis; RMTs methylate histone arginines; HATs acetylate histones; PRC2 methylates histones and DNA; Defective pyroptosis; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Neddylation; Potential therapeutics for SARS; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6; PKMTs methylate histone lysines; RNA Polymerase I Transcription Initiation; Regulation of TP53 Activity through Acetylation"	"Retinoblastoma gene in cancer; Interactome of polycomb repressive complex 2 (PRC2) ; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"20"	"0"	"83.0"	"138.4"	"321.0"	"109.1"	"133.1"	"101.6"	"420.4"	"122.3"	"145.3"	"114.8"	"99.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25786"	"Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1"	"40"	"9"	"15"	"9"	"263"	"29.5"	"6.61"	"3079.63"	"27.18"	"8"	"7"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00227, Pf10584"	"5682"	"ENSG00000129084"	"PSMA1"	"A8K400; hsa:5682; P25786; Q53YE8; Q9BRV9"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"62"	"0"	"555.9"	"587.9"	"2315.6"	"582.1"	"425.7"	"339.7"	"2142.8"	"508.8"	"542.1"	"569.5"	"575.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P15924"	"Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3"	"5"	"12"	"19"	"12"	"2871"	"331.6"	"6.81"	"2552.52"	"27.11"	"8"	"11"	"cell adhesion;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00681, Pf17902, Pf18373"	"1832"	"ENSG00000096696"	"DSP"	"B2RTT2; D7RX09; hsa:1832; O75993; P15924; Q14189; Q9UHN4"	"Formation of the cornified envelope; Neutrophil degranulation; RND3 GTPase cycle; RND1 GTPase cycle; Apoptotic cleavage of cell adhesion  proteins"	"Arrhythmogenic right ventricular cardiomyopathy; Lung fibrosis; Epithelial to mesenchymal transition in colorectal cancer"	"9"	"0"	"3165.5"	"1127.6"	"1641.2"	"994.8"	"504.2"	"423.8"	"1449.9"	"499.8"	"325.6"	"295.5"	"332.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P12814"	"Alpha-actinin-1 OS=Homo sapiens OX=9606 GN=ACTN1 PE=1 SV=2"	"10"	"8"	"17"	"2"	"892"	"103.0"	"5.41"	"3297.68"	"27.09"	"7"	"8"	"cell adhesion;cell organization and biogenesis;RNA metabolism OR transcription;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00307, Pf00435, Pf08726"	"87"	"ENSG00000072110"	"ACTN1"	"B3V8S3; B4DHH3; B7TY16; hsa:87; P12814; Q1HE25; Q9BTN1"	"Platelet degranulation ; RHOD GTPase cycle; RHOF GTPase cycle; Nephrin family interactions; Syndecan interactions; RHOBTB2 GTPase cycle; Regulation of cytoskeletal remodeling and cell spreading by IPP complex components"	"Arrhythmogenic right ventricular cardiomyopathy; Focal adhesion; Ebola virus infection in host; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Regulation of actin cytoskeleton"	"12"	"0"	"43.1"	"50.8"	"210.3"	"48.8"	"42.2"	"29.8"	"239.1"	"26.1"	"44.6"	"25.0"	"24.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49189"	"4-trimethylaminobutyraldehyde dehydrogenase OS=Homo sapiens OX=9606 GN=ALDH9A1 PE=1 SV=3"	"16"	"8"	"15"	"8"	"494"	"53.8"	"5.87"	"2652.64"	"27.07"	"6"	"8"	"cell organization and biogenesis;other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00171"	"223"	"ENSG00000143149"	"ALDH9A1"	"B2R6X1; B4DXY7; B9EKV4; hsa:223; P49189; Q5VV90; Q6LCL1; Q9NZT7"	"Carnitine synthesis"	"GABA receptor signaling; Fluoroacetic acid toxicity; Opioid receptor pathways"	"4"	"0"	"293.8"	"488.0"	"1510.1"	"439.6"	"409.7"	"399.4"	"2033.5"	"295.4"	"393.2"	"317.9"	"314.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BY44"	"Eukaryotic translation initiation factor 2A OS=Homo sapiens OX=9606 GN=EIF2A PE=1 SV=3"	"19"	"10"	"19"	"10"	"585"	"64.9"	"8.87"	"3633.40"	"27.03"	"10"	"7"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;translational apparatus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf08662"	"83939"	"ENSG00000144895"	"EIF2A"	"A8MPS6; B4DF96; B4DQ14; D3DNI9; hsa:83939; Q5QTR2; Q7Z4E9; Q8NFM1; Q96EW9; Q96K81; Q9BY44"	""	"Photodynamic therapy-induced unfolded protein response; VEGFA-VEGFR2 signaling; 7q11.23 copy number variation syndrome"	"3"	"0"	"658.0"	"600.6"	"1482.4"	"622.9"	"578.3"	"484.6"	"2010.7"	"589.5"	"925.2"	"1106.5"	"1697.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99873"	"Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3"	"18"	"6"	"14"	"6"	"371"	"42.4"	"5.35"	"2725.54"	"26.68"	"6"	"6"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13649"	"3276"	"ENSG00000126457"	"PRMT1"	"A0A087X1W2; B4E3C3; G5E9B6; H7C2I1; hsa:3276; Q15529; Q2VP93; Q6LEU5; Q8WUW5; Q99872; Q99873; Q99874; Q9NZ04; Q9NZ05; Q9NZ06"	"Extra-nuclear estrogen signaling; Estrogen-dependent gene expression; RMTs methylate histone arginines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Maturation of nucleoprotein"	"Energy metabolism; mRNA processing; Nitric oxide metabolism in cystic fibrosis; 16p11.2 distal deletion syndrome; Interferon type I signaling pathways"	"11"	"0"	"399.1"	"435.2"	"1589.9"	"458.3"	"447.0"	"343.8"	"1681.7"	"203.2"	"655.4"	"538.0"	"398.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61313"	"60S ribosomal protein L15 OS=Homo sapiens OX=9606 GN=RPL15 PE=1 SV=2"	"28"	"6"	"17"	"6"	"204"	"24.1"	"11.62"	"3309.23"	"26.63"	"6"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00827"	"6138"	"ENSG00000174748"	"RPL15"	"hsa:6138; P39030; P41051; P61313; Q5U0C0; Q642I1; Q6IPX6; Q8WYP2; Q96C44; Q9H2E5"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"830.7"	"947.9"	"2609.8"	"738.5"	"729.7"	"639.8"	"3220.0"	"434.0"	"565.0"	"389.2"	"371.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86VN1"	"Vacuolar protein-sorting-associated protein 36 OS=Homo sapiens OX=9606 GN=VPS36 PE=1 SV=1"	"22"	"7"	"15"	"7"	"386"	"43.8"	"7.20"	"2547.60"	"26.61"	"7"	"7"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport"	"other membranes;cytosol;nucleus;other cytoplasmic organelle"	"other molecular function"	"Pf04157, Pf11605"	"51028"	"ENSG00000136100"	"VPS36"	"A8K125; hsa:51028; Q3ZCV7; Q5H9S1; Q5VXB6; Q86VN1; Q9H8Z5; Q9Y3E3"	"Endosomal Sorting Complex Required For Transport (ESCRT); HCMV Late Events"	"Network map of SARS-CoV-2 signaling pathway"	"3"	"0"	"190.0"	"184.3"	"554.6"	"186.1"	"196.5"	"174.8"	"674.1"	"265.3"	"942.7"	"1534.2"	"1939.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NBS9"	"Thioredoxin domain-containing protein 5 OS=Homo sapiens OX=9606 GN=TXNDC5 PE=1 SV=2"	"22"	"7"	"10"	"7"	"432"	"47.6"	"5.97"	"1204.55"	"26.52"	"4"	"6"	"other biological processes"	"non-structural extracellular;ER/Golgi;other cytoplasmic organelle"	"other molecular function"	"Pf00085"	"81567"	"ENSG00000239264"	"TXNDC5"	"B2RDM2; hsa:81567; Q5TCQ0; Q8NBS9; Q8ND33; Q8TCT2; Q9BVH9"	"Neutrophil degranulation; Lysosome Vesicle Biogenesis; Golgi Associated Vesicle Biogenesis"	"VEGFA-VEGFR2 signaling"	"4"	"0"	"646.2"	"723.1"	"1609.0"	"792.5"	"676.4"	"671.0"	"1968.5"	"548.9"	"744.0"	"559.2"	"620.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NR30"	"Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5"	"10"	"7"	"14"	"7"	"783"	"87.3"	"9.28"	"2873.44"	"26.38"	"6"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf08152"	"9188"	"ENSG00000165732"	"DDX21"	"B2RDL0; hsa:9188; Q13436; Q5VX41; Q68D35; Q9NR30"	"B-WICH complex positively regulates rRNA expression; Major pathway of rRNA processing in the nucleolus and cytosol"	""	"2"	"0"	"304.8"	"330.1"	"1183.7"	"314.7"	"312.3"	"264.1"	"1257.9"	"164.4"	"265.0"	"259.7"	"268.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25685"	"DnaJ homolog subfamily B member 1 OS=Homo sapiens OX=9606 GN=DNAJB1 PE=1 SV=4"	"31"	"10"	"18"	"9"	"340"	"38.0"	"8.63"	"2912.40"	"26.36"	"9"	"9"	"RNA metabolism OR transcription;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00226, Pf01556"	"3337"	"ENSG00000132002"	"DNAJB1"	"B4DX52; hsa:3337; P25685"	"MAPK6/MAPK4 signaling; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Regulation of HSF1-mediated heat shock response; Attenuation phase"	"Nuclear receptors meta-pathway; NRF2 pathway"	"7"	"1"	"900.3"	"883.5"	"2831.0"	"864.9"	"757.6"	"607.2"	"3001.5"	"448.0"	"693.3"	"585.2"	"629.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q4VCS5"	"Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1"	"10"	"9"	"16"	"8"	"1084"	"118.0"	"7.64"	"2176.16"	"26.33"	"7"	"9"	"cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf12240"	"154796"	"ENSG00000126016"	"AMOT"	"hsa:154796; Q4VCS5; Q504X5; Q9HD27; Q9UPT1"	""	"VEGFA-VEGFR2 signaling; Hippo-Merlin signaling dysregulation; Pleural mesothelioma"	"3"	"0"	"493.5"	"530.8"	"1520.7"	"429.4"	"419.7"	"348.2"	"1799.4"	"293.4"	"422.6"	"416.5"	"507.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31689"	"DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2"	"14"	"4"	"9"	"4"	"397"	"44.8"	"7.08"	"1002.66"	"26.26"	"3"	"3"	"stress response;transport;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00226, Pf00684, Pf01556"	"3301"	"ENSG00000086061"	"DNAJA1"	"hsa:3301; P31689; Q5T7Q0; Q86TL9"	"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand"	"VEGFA-VEGFR2 signaling; Exercise-induced circadian regulation"	"3"	"0"	"311.7"	"287.3"	"1682.3"	"301.1"	"170.6"	"145.2"	"1291.3"	"93.9"	"149.6"	"109.8"	"115.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75821"	"Eukaryotic translation initiation factor 3 subunit G OS=Homo sapiens OX=9606 GN=EIF3G PE=1 SV=2"	"18"	"5"	"10"	"5"	"320"	"35.6"	"6.13"	"1612.62"	"26.26"	"4"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf12353"	"8666"	"ENSG00000130811"	"EIF3G"	"hsa:8666; O14801; O75821; Q969U5"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"8"	"0"	"431.0"	"454.4"	"1349.3"	"464.0"	"452.2"	"385.0"	"1645.7"	"234.2"	"429.9"	"311.6"	"312.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P29401"	"Transketolase OS=Homo sapiens OX=9606 GN=TKT PE=1 SV=3"	"9"	"5"	"15"	"5"	"623"	"67.8"	"7.66"	"2566.08"	"26.24"	"4"	"5"	"other metabolic processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle"	"other molecular function"	"Pf00456, Pf02779, Pf02780"	"7086"	"ENSG00000163931"	"TKT"	"A8K089; B4DE31; E7EPA7; hsa:7086; P29401; Q8TBA3; Q96HH3"	"NFE2L2 regulates pentose phosphate pathway genes; Pentose phosphate pathway; Insulin effects increased synthesis of Xylulose-5-Phosphate"	"Pentose phosphate metabolism; VEGFA-VEGFR2 signaling; Metabolic reprogramming in colon cancer; Thiamine metabolic pathways"	"7"	"0"	"156.4"	"208.1"	"1681.4"	"238.4"	"116.1"	"118.4"	"1145.8"	"90.5"	"160.6"	"132.9"	"147.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75347"	"Tubulin-specific chaperone A OS=Homo sapiens OX=9606 GN=TBCA PE=1 SV=3"	"61"	"10"	"16"	"10"	"108"	"12.8"	"5.29"	"3233.90"	"26.18"	"8"	"8"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02970"	"6902"	"ENSG00000171530"	"TBCA"	"B4DT30; hsa:6902; O75347"	"Post-chaperonin tubulin folding pathway"	"VEGFA-VEGFR2 signaling"	"2"	"0"	"705.8"	"740.0"	"3750.8"	"751.4"	"732.8"	"442.5"	"5802.8"	"412.0"	"543.8"	"392.7"	"368.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13693"	"Translationally-controlled tumor protein OS=Homo sapiens OX=9606 GN=TPT1 PE=1 SV=1"	"34"	"5"	"12"	"5"	"172"	"19.6"	"4.93"	"2668.05"	"26.03"	"5"	"4"	"transport;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00838"	"7178"	"ENSG00000133112"	"TPT1"	"B2R7E5; hsa:7178; P13693; Q6YLS2; Q7Z4J4; Q8TBK7; Q96EE2; Q9UC70"	""	""	"0"	"0"	"505.9"	"550.4"	"2190.7"	"581.4"	"480.8"	"342.6"	"2521.7"	"307.7"	"529.9"	"521.8"	"703.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14737"	"Programmed cell death protein 5 OS=Homo sapiens OX=9606 GN=PDCD5 PE=1 SV=3"	"46"	"8"	"21"	"8"	"125"	"14.3"	"6.04"	"4223.54"	"25.86"	"8"	"6"	"other biological processes"	"cytosol;nucleus"	"enzyme regulator activity;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf01984"	"9141"	"ENSG00000105185"	"PDCD5"	"B4DE64; hsa:9141; O14737; Q53YC9; Q6IB70"	""	""	"0"	"0"	"1050.8"	"1456.8"	"3675.3"	"1253.6"	"1607.3"	"1504.9"	"4365.5"	"979.9"	"1611.9"	"1099.5"	"996.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P38117"	"Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3"	"28"	"8"	"15"	"8"	"255"	"27.8"	"8.10"	"3434.99"	"25.79"	"7"	"6"	"other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf01012"	"2109"	"ENSG00000105379"	"ETFB"	"A8K766; B3KNY2; hsa:2109; P38117; Q6IBH7; Q71RF6; Q9Y3S7"	"Respiratory electron transport; Protein methylation"	""	"2"	"0"	"430.7"	"476.3"	"2652.5"	"483.1"	"393.3"	"301.1"	"3800.8"	"278.7"	"352.1"	"298.0"	"262.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62851"	"40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1"	"38"	"6"	"19"	"6"	"125"	"13.7"	"10.11"	"3299.48"	"25.70"	"6"	"6"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf03297"	"6230"	"ENSG00000118181; ENSG00000280831"	"RPS25"	"B2R4M7; hsa:6230; P25111; P62851"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"1119.9"	"1277.5"	"3343.0"	"989.2"	"925.4"	"841.0"	"3646.2"	"441.2"	"582.1"	"480.0"	"468.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P21796"	"Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2"	"33"	"8"	"15"	"8"	"283"	"30.8"	"8.54"	"2752.95"	"25.61"	"7"	"8"	"cell-cell signaling;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;mitochondrion;other cell component"	"transporter activity;other molecular function"	"Pf01459"	"7416"	"ENSG00000213585"	"VDAC1"	"B3KVK4; D3DQ93; hsa:7416; P21796; Q5FVE7; Q9UIQ5; Q9UPL0"	"Ub-specific processing proteases; Pyruvate metabolism; Mitochondrial protein import; PINK1-PRKN Mediated Mitophagy; Mitochondrial calcium ion transport"	"Alzheimer's disease and miRNA effects; Alzheimer's disease; Arsenic metabolism and reactive oxygen species generation; Cholesterol metabolism; Fatty Acids and Lipoproteins Transport in Hepatocytes"	"10"	"0"	"797.0"	"738.1"	"3527.1"	"638.1"	"466.9"	"315.3"	"2836.2"	"179.0"	"319.6"	"240.5"	"259.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35998"	"26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3"	"28"	"12"	"20"	"12"	"433"	"48.6"	"5.95"	"4079.39"	"25.59"	"11"	"8"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf17862"	"5701"	"ENSG00000161057"	"PSMC2"	"A4D0Q1; B7Z5E2; hsa:5701; P35998; Q3LIA5; Q9UDI3"	"Regulation of expression of SLITs and ROBOs; Separation of Sister Chromatids; Neutrophil degranulation; The role of GTSE1 in G2/M progression after G2 checkpoint; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; SCF(Skp2)-mediated degradation of p27/p21; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"64"	"0"	"528.9"	"539.7"	"1805.6"	"552.0"	"484.2"	"379.8"	"1982.2"	"214.9"	"366.6"	"303.0"	"313.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BUJ2"	"Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2"	"13"	"10"	"16"	"9"	"856"	"95.7"	"6.92"	"2541.80"	"25.54"	"7"	"9"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00622, Pf02037, Pf13671"	"11100"	"ENSG00000105323"	"HNRNPUL1"	"B3KMW7; hsa:11100; O76022; Q6ZSZ0; Q7L8P4; Q8N6Z4; Q96G37; Q9BUJ2; Q9HAL3; Q9UG75"	""	""	"0"	"0"	"611.6"	"668.8"	"2097.1"	"711.3"	"593.5"	"562.5"	"2665.4"	"363.4"	"627.9"	"492.8"	"501.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P42765"	"3-ketoacyl-CoA thiolase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAA2 PE=1 SV=2"	"24"	"8"	"14"	"8"	"397"	"41.9"	"8.09"	"2510.00"	"25.49"	"7"	"7"	"cell organization and biogenesis;other metabolic processes;stress response;transport"	"mitochondrion"	"other molecular function"	"Pf00108, Pf02803"	"10449"	"ENSG00000167315"	"ACAA2"	"hsa:10449; P42765; Q9BUT6"	"Mitochondrial Fatty Acid Beta-Oxidation"	"Fatty acid biosynthesis; 10q11.21q11.23 copy number variation syndrome"	"3"	"0"	"621.6"	"726.7"	"1920.0"	"749.8"	"595.9"	"412.8"	"2068.5"	"372.7"	"604.4"	"920.4"	"1465.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25787"	"Proteasome subunit alpha type-2 OS=Homo sapiens OX=9606 GN=PSMA2 PE=1 SV=2"	"26"	"5"	"10"	"5"	"234"	"25.9"	"7.43"	"1345.11"	"25.49"	"3"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	""	"Pf00227, Pf10584"	"5683"	"ENSG00000106588"	"PSMA2"	"hsa:5683; P25787; Q6ICS6; Q9BU45"	"Neutrophil degranulation; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"63"	"0"	"294.2"	"282.3"	"1224.3"	"258.9"	"164.7"	"137.2"	"1095.8"	"204.7"	"247.9"	"214.7"	"246.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61158"	"Actin-related protein 3 OS=Homo sapiens OX=9606 GN=ACTR3 PE=1 SV=3"	"20"	"6"	"12"	"6"	"418"	"47.3"	"5.88"	"1883.47"	"25.42"	"5"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00022"	"10096"	"ENSG00000115091"	"ACTR3"	"hsa:10096; P32391; P61158; Q53QM2"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Clathrin-mediated endocytosis; EPHB-mediated forward signaling"	"Physico-chemical features and toxicity-associated pathways"	"6"	"0"	"375.6"	"433.4"	"1609.3"	"390.5"	"322.8"	"230.6"	"1654.5"	"321.8"	"717.6"	"1548.1"	"2513.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NTJ3"	"Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2"	"8"	"9"	"16"	"9"	"1288"	"147.1"	"6.79"	"2753.11"	"25.39"	"8"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02463, Pf06470"	"10051"	"ENSG00000113810"	"SMC4"	"A6NLT9; D3DNL8; hsa:10051; O95752; Q8NDL4; Q9NTJ3; Q9UNT9"	"Condensation of Prophase Chromosomes; Condensation of Prometaphase Chromosomes"	"Ciliary landscape"	"3"	"0"	"557.9"	"600.8"	"2155.7"	"545.5"	"454.3"	"407.5"	"1447.8"	"245.5"	"454.0"	"422.4"	"442.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92900"	"Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2"	"8"	"6"	"11"	"6"	"1129"	"124.3"	"6.61"	"2654.36"	"25.34"	"5"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09416, Pf13086, Pf13087, Pf18141"	"5976"	"ENSG00000005007"	"UPF1"	"hsa:5976; O00239; O43343; Q86Z25; Q92842; Q92900"	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Pathophysiological roles of DUX4 in FSHD1"	"3"	"0"	"360.3"	"380.9"	"1324.2"	"342.5"	"357.7"	"271.1"	"1542.6"	"214.3"	"347.2"	"263.6"	"260.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P39748"	"Flap endonuclease 1 OS=Homo sapiens OX=9606 GN=FEN1 PE=1 SV=1"	"16"	"6"	"13"	"6"	"380"	"42.6"	"8.62"	"2858.67"	"25.34"	"6"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00752, Pf00867"	"2237"	"ENSG00000168496"	"FEN1"	"hsa:2237; P39748"	"HDR through MMEJ (alt-NHEJ); Early Phase of HIV Life Cycle; POLB-Dependent Long Patch Base Excision Repair; PCNA-Dependent Long Patch Base Excision Repair; Removal of the Flap Intermediate; Removal of the Flap Intermediate from the C-strand"	"Base excision repair; DNA repair pathways, full network"	"8"	"0"	"477.1"	"475.4"	"1891.7"	"516.3"	"352.3"	"289.5"	"1480.0"	"248.3"	"376.3"	"403.5"	"607.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P38159"	"RNA-binding motif protein, X chromosome OS=Homo sapiens OX=9606 GN=RBMX PE=1 SV=3"	"19"	"6"	"15"	"3"	"391"	"42.3"	"10.05"	"2729.38"	"25.10"	"6"	"6"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08081"	"27316"	"ENSG00000147274"	"RBMX"	"B4E3U4; D3DWH0; E9PG86; hsa:27316; P38159; Q5JQ67; Q8N8Y7; Q969R3"	"mRNA Splicing - Major Pathway; RND2 GTPase cycle; RND3 GTPase cycle; RND1 GTPase cycle; Processing of Capped Intron-Containing Pre-mRNA; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle"	"mRNA processing"	"8"	"2"	"630.3"	"697.3"	"2704.8"	"571.4"	"520.8"	"423.0"	"3658.5"	"412.2"	"678.0"	"443.7"	"485.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60660"	"Myosin light polypeptide 6 OS=Homo sapiens OX=9606 GN=MYL6 PE=1 SV=2"	"53"	"7"	"16"	"6"	"151"	"16.9"	"4.65"	"3319.09"	"25.09"	"7"	"6"	"other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	""	"4637"	"ENSG00000092841"	"MYL6"	"hsa:4637; P16475; P24572; P24573; P60660; Q12790; Q561V9; Q6IAZ0; Q6IPY5"	"Smooth Muscle Contraction; RHO GTPases activate CIT; EPHA-mediated growth cone collapse; Sema4D induced cell migration and growth-cone collapse; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; RHO GTPases activate PAKs"	"Ciliary landscape"	"8"	"1"	"699.5"	"831.7"	"3278.8"	"685.9"	"515.1"	"370.7"	"2680.1"	"305.1"	"502.6"	"441.6"	"571.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96PK6"	"RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2"	"15"	"9"	"16"	"9"	"669"	"69.4"	"9.67"	"2469.29"	"25.06"	"8"	"8"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00076"	"100526737; 10432"	"ENSG00000239306"	"RBM14"	"B0LM41; B3KMN4; D6RGD8; hsa:100526737; hsa:10432; O75932; Q2PYN1; Q53GV1; Q68DQ9; Q96PK5; Q96PK6"	"RUNX2 regulates bone development"	"Ciliary landscape"	"2"	"0"	"570.4"	"530.9"	"1359.1"	"527.8"	"587.2"	"449.6"	"2367.3"	"835.0"	"1110.9"	"954.8"	"1041.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P16949"	"Stathmin OS=Homo sapiens OX=9606 GN=STMN1 PE=1 SV=3"	"54"	"8"	"15"	"8"	"149"	"17.3"	"5.97"	"2391.43"	"25.06"	"7"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf00836"	"3925"	"ENSG00000117632"	"STMN1"	"A2A2D1; B2R4E7; B7Z8N4; D3DPJ5; hsa:3925; P16949"	"Nuclear signaling by ERBB4"	"Microtubule cytoskeleton regulation; Retinoblastoma gene in cancer; RAC1/PAK1/p38/MMP2 pathway; MAPK signaling pathway; EGF/EGFR signaling pathway; IL-18 signaling pathway"	"7"	"0"	"523.4"	"583.4"	"2945.1"	"598.3"	"591.2"	"414.3"	"4616.1"	"394.4"	"518.7"	"451.3"	"548.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51665"	"26S proteasome non-ATPase regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMD7 PE=1 SV=2"	"31"	"8"	"13"	"8"	"324"	"37.0"	"6.77"	"2222.05"	"25.03"	"6"	"7"	"protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf01398, Pf13012"	"5713"	"ENSG00000103035"	"PSMD7"	"D3DWS9; hsa:5713; P51665; Q6PKI2; Q96E97"	"Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Neutrophil degranulation; Regulation of expression of SLITs and ROBOs; Orc1 removal from chromatin; Assembly of the pre-replicative complex; Antigen processing: Ubiquitination & Proteasome degradation; Regulation of PTEN stability and activity; Degradation of GLI1 by the proteasome; Hedgehog 'on' state; FCERI mediated NF-kB activation; Downstream TCR signaling; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Ciliary landscape; Alzheimer's disease"	"65"	"0"	"500.8"	"570.2"	"1906.0"	"563.6"	"563.2"	"455.6"	"1747.7"	"245.0"	"368.8"	"364.5"	"351.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35268"	"60S ribosomal protein L22 OS=Homo sapiens OX=9606 GN=RPL22 PE=1 SV=2"	"55"	"6"	"11"	"6"	"128"	"14.8"	"9.19"	"2170.63"	"24.97"	"5"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01776"	"6146"	"ENSG00000116251"	"RPL22"	"B2R495; hsa:6146; P35268; Q6IBD1"	"SRP-dependent cotranslational protein targeting to membrane; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"444.2"	"523.6"	"1803.5"	"567.7"	"486.5"	"401.6"	"2326.4"	"227.4"	"388.6"	"253.1"	"261.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16181"	"Septin-7 OS=Homo sapiens OX=9606 GN=SEPTIN7 PE=1 SV=2"	"19"	"7"	"17"	"6"	"437"	"50.6"	"8.63"	"3314.38"	"24.88"	"7"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00735"	"989"	"ENSG00000122545"	"SEPTIN7"	"hsa:989; Q16181; Q52M76; Q6NX50"	"MAPK6/MAPK4 signaling"	""	"1"	"1"	"478.7"	"491.7"	"1896.1"	"525.0"	"462.1"	"350.3"	"1244.3"	"183.5"	"329.8"	"273.4"	"524.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P42285"	"Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3"	"9"	"7"	"12"	"7"	"1042"	"117.7"	"6.52"	"1855.27"	"24.84"	"5"	"6"	"RNA metabolism OR transcription;other metabolic processes;stress response"	"nucleus"	"other molecular function"	"Pf00270, Pf00271, Pf08148, Pf13234"	"23517"	"ENSG00000039123"	"MTREX"	"hsa:23517; P42285; Q2M386; Q6MZZ8; Q6P170; Q8N5R0; Q8TAG2"	"mRNA Splicing - Major Pathway; Major pathway of rRNA processing in the nucleolus and cytosol"	""	"2"	"0"	"217.3"	"221.2"	"750.4"	"216.8"	"210.5"	"163.5"	"633.6"	"98.7"	"175.1"	"170.6"	"234.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z6Z7"	"E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3"	"3"	"8"	"11"	"8"	"4374"	"481.6"	"5.22"	"1767.81"	"24.84"	"5"	"6"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00627, Pf00632, Pf02825, Pf06012, Pf06025, Pf14377"	"10075"	"ENSG00000086758"	"HUWE1"	"hsa:10075; O15029; Q4G2Z2; Q5H961; Q6P4D0; Q7Z6Z7; Q8NG67; Q9BUI0; Q9HCJ4; Q9NSL6; Q9P0A9"	"Antigen processing: Ubiquitination & Proteasome degradation; Neutrophil degranulation"	""	"2"	"0"	"141.6"	"153.8"	"574.4"	"149.2"	"160.8"	"100.2"	"594.5"	"69.8"	"100.2"	"90.1"	"80.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UNM6"	"26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2"	"22"	"8"	"18"	"8"	"376"	"42.9"	"5.81"	"3408.50"	"24.82"	"8"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf01399"	"5719"	"ENSG00000185627"	"PSMD13"	"B3KT15; hsa:5719; O75831; Q53XU2; Q9UNM6; Q9UNV3"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Ciliary landscape; Alzheimer's disease"	"65"	"0"	"979.3"	"935.8"	"3521.4"	"976.7"	"786.1"	"624.5"	"2749.1"	"318.8"	"534.2"	"458.8"	"438.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P12236"	"ADP/ATP translocase 3 OS=Homo sapiens OX=9606 GN=SLC25A6 PE=1 SV=4"	"29"	"10"	"20"	"2"	"298"	"32.8"	"9.74"	"3651.30"	"24.71"	"9"	"7"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity"	"Pf00153"	"293"	"ENSG00000169100"	"SLC25A6"	"hsa:293; P12236; Q96C49"	"Mitochondrial protein import; Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane; Influenza Virus Induced Apoptosis; Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization"	"Electron transport chain: OXPHOS system in mitochondria; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"7"	"0"	"248.2"	"225.0"	"938.4"	"196.5"	"177.0"	"129.1"	"836.3"	"60.8"	"97.9"	"83.5"	"70.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35580"	"Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3"	"5"	"9"	"18"	"4"	"1976"	"228.9"	"5.54"	"2855.49"	"24.70"	"9"	"9"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00063, Pf00612, Pf01576, Pf02736"	"4628"	"ENSG00000133026"	"MYH10"	"B2RWP9; D3DTS1; F8VTL3; hsa:4628; P35580; Q12989; Q149N3; Q149N4; Q16087; Q4LE45; Q6PK16; Q9BWG0"	"Sema4D induced cell migration and growth-cone collapse; RHO GTPases activate PAKs; RHO GTPases activate CIT; EPHA-mediated growth cone collapse; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs"	"Regulation of actin cytoskeleton"	"7"	"1"	"601.3"	"488.8"	"1958.5"	"484.1"	"265.3"	"209.8"	"1333.0"	"131.3"	"223.0"	"224.4"	"270.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60547"	"GDP-mannose 4,6 dehydratase OS=Homo sapiens OX=9606 GN=GMDS PE=1 SV=1"	"21"	"5"	"10"	"5"	"372"	"41.9"	"7.31"	"1938.19"	"24.68"	"4"	"5"	"other metabolic processes;signal transduction"	"cytosol;other cell component"	"other molecular function"	"Pf16363"	"2762"	"ENSG00000112699"	"GMDS"	"E9PI88; hsa:2762; O60547; O75357; Q5T954; Q6FH09; Q9UGZ3; Q9UJK9"	"GDP-fucose biosynthesis"	""	"1"	"0"	"259.5"	"388.7"	"793.6"	"335.1"	"305.5"	"292.9"	"1054.4"	"318.8"	"486.9"	"438.0"	"506.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P26640"	"Valine--tRNA ligase OS=Homo sapiens OX=9606 GN=VARS1 PE=1 SV=4"	"8"	"8"	"15"	"8"	"1264"	"140.4"	"7.59"	"3199.21"	"24.67"	"8"	"7"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol"	"other molecular function"	"Pf00043, Pf00133, Pf08264"	"7407"	"ENSG00000096171; ENSG00000204394; ENSG00000224264; ENSG00000226589; ENSG00000231116"	"VARS1"	"B0V1N1; B4DZ61; hsa:7407; P26640; Q5JQ90; Q96E77; Q9UQM2"	"Cytosolic tRNA aminoacylation"	"Amino acid metabolism"	"2"	"0"	"330.3"	"335.3"	"1177.0"	"372.5"	"308.6"	"250.6"	"1138.4"	"184.5"	"270.1"	"243.8"	"239.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14678"	"Small nuclear ribonucleoprotein-associated proteins B and B' OS=Homo sapiens OX=9606 GN=SNRPB PE=1 SV=2"	"25"	"7"	"15"	"7"	"240"	"24.6"	"11.19"	"2129.56"	"24.59"	"6"	"7"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01423"	"6628"	"ENSG00000125835"	"SNRPB"	"hsa:6628; P14678; Q15490; Q6IB35; Q9UIS5"	"snRNP Assembly; RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway; SARS-CoV-2 modulates host translation machinery; mRNA Splicing - Minor Pathway; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"mRNA processing"	"8"	"0"	"596.8"	"735.4"	"2613.4"	"715.7"	"608.8"	"530.7"	"2807.9"	"322.5"	"435.3"	"377.9"	"326.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61224"	"Ras-related protein Rap-1b OS=Homo sapiens OX=9606 GN=RAP1B PE=1 SV=1"	"35"	"6"	"14"	"6"	"184"	"20.8"	"5.78"	"3187.14"	"24.40"	"6"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00071"	"5908"	"ENSG00000127314"	"RAP1B"	"B2R5Z2; B4DQI8; B4DW74; B4DW94; hsa:5908; P09526; P61224; Q502X3; Q5TZR4; Q6DCA1; Q6LES0"	"Neutrophil degranulation; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Signaling by BRAF and RAF1 fusions; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; Rap1 signalling; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; GRB2:SOS provides linkage to MAPK signaling for Integrins ; p130Cas linkage to MAPK signaling for integrins; MET activates RAP1 and RAC1"	"Integrin-mediated cell adhesion; Thyroid stimulating hormone (TSH) signaling pathway; Androgen receptor network in prostate cancer; Corticotropin-releasing hormone signaling pathway; Common pathways underlying drug addiction; Focal adhesion; Hepatocyte growth factor receptor signaling; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Ras signaling"	"25"	"0"	"451.6"	"505.2"	"1450.1"	"454.7"	"430.4"	"341.3"	"2143.6"	"394.1"	"566.5"	"498.6"	"479.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P67775"	"Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform OS=Homo sapiens OX=9606 GN=PPP2CA PE=1 SV=1"	"28"	"6"	"11"	"6"	"309"	"35.6"	"5.54"	"1923.22"	"24.40"	"5"	"6"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00149"	"5515"	"ENSG00000113575"	"PPP2CA"	"hsa:5515; P05323; P13197; P67775"	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Regulation of TP53 Degradation; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Cyclin D associated events in G1; Disassembly of the destruction complex and recruitment of AXIN to the membrane; RAF activation; Cyclin A/B1/B2 associated events during G2/M transition; Beta-catenin phosphorylation cascade; Signaling by GSK3beta mutants; CTNNB1 S33 mutants aren't phosphorylated; CTNNB1 S37 mutants aren't phosphorylated; CTNNB1 S45 mutants aren't phosphorylated; CTNNB1 T41 mutants aren't phosphorylated; APC truncation mutants have impaired AXIN binding; AXIN missense mutants destabilize the destruction complex; Truncations of AMER1 destabilize the destruction complex; Spry regulation of FGF signaling; MASTL Facilitates Mitotic Progression; Regulation of glycolysis by fructose 2,6-bisphosphate metabolism; Initiation of Nuclear Envelope (NE) Reformation; Negative regulation of MAPK pathway; Platelet sensitization by LDL; CTLA4 inhibitory signaling; Inhibition of replication initiation of damaged DNA by RB1/E2F1; DARPP-32 events; PP2A-mediated dephosphorylation of key metabolic factors; ERKs are inactivated"	"Sphingolipid pathway; TNF-alpha signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Dopamine metabolism; Mesodermal commitment pathway; Mesodermal commitment pathway; Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Wnt signaling pathway and pluripotency; PI3K-Akt signaling pathway; Cancer immunotherapy by CTLA4 blockade; FGFR3 signaling in chondrocyte proliferation and terminal differentiation; 16p11.2 proximal deletion syndrome; Glycogen synthesis and degradation; Cohesin complex - Cornelia de Lange syndrome"	"52"	"0"	"367.6"	"489.1"	"1542.2"	"510.1"	"518.5"	"399.2"	"1710.8"	"275.2"	"465.7"	"343.3"	"344.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBE0"	"SUMO-activating enzyme subunit 1 OS=Homo sapiens OX=9606 GN=SAE1 PE=1 SV=1"	"21"	"8"	"15"	"8"	"346"	"38.4"	"5.30"	"2456.83"	"24.30"	"7"	"8"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00899"	"10055"	"ENSG00000142230"	"SAE1"	"B2RDP5; B3KMQ2; F5GXX7; G3XAK6; hsa:10055; O95717; Q9P020; Q9UBE0"	"SUMO is conjugated to E1 (UBA2:SAE1); SUMO is transferred from E1 to E2 (UBE2I, UBC9)"	""	"2"	"0"	"280.2"	"342.7"	"1341.2"	"276.2"	"248.8"	"182.8"	"1375.3"	"131.2"	"201.0"	"151.5"	"129.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q04760"	"Lactoylglutathione lyase OS=Homo sapiens OX=9606 GN=GLO1 PE=1 SV=4"	"48"	"8"	"17"	"8"	"184"	"20.8"	"5.31"	"3239.97"	"24.12"	"7"	"7"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00903"	"2739"	"ENSG00000124767"	"GLO1"	"B2R6P7; B4DDV0; hsa:2739; P78375; Q04760; Q59EL0; Q5TZW3; Q96FC0; Q96J41"	"Pyruvate metabolism"	""	"1"	"0"	"701.7"	"858.0"	"3605.1"	"760.8"	"683.9"	"475.0"	"3834.0"	"433.3"	"503.5"	"373.6"	"363.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HC38"	"Glyoxalase domain-containing protein 4 OS=Homo sapiens OX=9606 GN=GLOD4 PE=1 SV=1"	"25"	"7"	"15"	"7"	"313"	"34.8"	"5.60"	"2420.69"	"24.09"	"6"	"7"	""	"mitochondrion"	""	""	"51031"	"ENSG00000167699"	"GLOD4"	"D3DTG9; D3DTH1; hsa:51031; Q96B89; Q9H3J8; Q9HC37; Q9HC38; Q9NVN1"	""	""	"0"	"0"	"417.5"	"481.4"	"1959.7"	"461.3"	"472.8"	"348.5"	"2604.4"	"319.7"	"564.7"	"508.3"	"450.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23588"	"Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2"	"16"	"8"	"14"	"8"	"611"	"69.1"	"5.73"	"2557.85"	"23.92"	"7"	"7"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus"	"nucleic acid binding activity"	"Pf00076"	"1975"	"ENSG00000063046"	"EIF4B"	"B4DS13; hsa:1975; P23588; Q4G0E3; Q53HQ2; Q6GPH5; Q6IB46; Q8WYK5"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Deadenylation of mRNA; mTORC1-mediated signalling"	"Translation factors; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Translation inhibitors in chronically activated PDGFRA cells; Perturbations to host-cell autophagy, induced by SARS-CoV-2 proteins; Pleural mesothelioma; Interferon type I signaling pathways"	"14"	"0"	"480.1"	"489.2"	"1730.1"	"511.2"	"473.9"	"417.7"	"2482.5"	"356.8"	"523.1"	"365.2"	"316.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14978"	"Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2"	"13"	"9"	"14"	"9"	"699"	"73.6"	"9.47"	"2038.59"	"23.90"	"6"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05022"	"9221"	"ENSG00000166197"	"NOLC1"	"hsa:9221; Q14978; Q15030; Q5VV70; Q9BUV3"	""	""	"0"	"0"	"987.4"	"979.1"	"3087.9"	"896.7"	"828.4"	"823.4"	"4272.3"	"1325.7"	"952.1"	"866.6"	"938.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51991"	"Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2"	"22"	"7"	"15"	"5"	"378"	"39.6"	"9.01"	"3044.72"	"23.89"	"5"	"5"	"RNA metabolism OR transcription;other metabolic processes;transport"	"nucleus;other cell component"	"transporter activity;nucleic acid binding activity"	"Pf00076"	"220988"	"ENSG00000170144"	"HNRNPA3"	"D3DPF4; hsa:220988; P51991; Q53RW7; Q6URK5"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	""	"2"	"0"	"465.4"	"499.6"	"1616.9"	"485.4"	"456.1"	"359.2"	"2134.7"	"337.4"	"643.5"	"397.0"	"420.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"E9PAV3"	"Nascent polypeptide-associated complex subunit alpha, muscle-specific form OS=Homo sapiens OX=9606 GN=NACA PE=1 SV=1"	"1"	"3"	"14"	"3"	"2078"	"205.3"	"9.58"	"2529.48"	"23.78"	"3"	"3"	"transport"	"translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01849, Pf19026"	""	"ENSG00000196531"	"NACA"	"E9PAV3"	""	""	"0"	"0"	"63.4"	"76.6"	"207.9"	"72.5"	"100.8"	"67.2"	"267.2"	"60.2"	"84.3"	"92.7"	"67.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q10567"	"AP-1 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP1B1 PE=1 SV=2"	"10"	"8"	"14"	"4"	"949"	"104.6"	"5.06"	"2469.94"	"23.64"	"7"	"7"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"112.1"	"137.4"	"494.6"	"123.2"	"117.6"	"101.5"	"575.4"	"210.6"	"588.9"	"519.5"	"608.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P48444"	"Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1"	"16"	"7"	"14"	"7"	"511"	"57.2"	"6.21"	"2585.96"	"23.63"	"7"	"7"	"transport;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi"	""	"Pf00928, Pf01217"	"372"	"ENSG00000095139"	"ARCN1"	"B4E1X2; E9PEU4; hsa:372; P48444; Q52M80"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport"	"miR-517 relationship with ARCN1 and USP1"	"3"	"0"	"289.6"	"393.4"	"1330.7"	"390.3"	"354.7"	"288.5"	"1388.2"	"242.0"	"332.8"	"300.8"	"289.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13435"	"Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2"	"9"	"7"	"13"	"7"	"895"	"100.2"	"5.67"	"2902.64"	"23.54"	"7"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf02037, Pf04037, Pf04046"	"10992"	"ENSG00000087365"	"SF3B2"	"A8K485; B4DT19; hsa:10992; Q13435; Q7L4T5; Q7Z627; Q969K1; Q96CM6; Q9BWD2"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"mRNA processing"	"3"	"0"	"731.6"	"743.0"	"2690.5"	"794.7"	"766.2"	"657.0"	"3218.7"	"402.8"	"603.5"	"458.7"	"447.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BXP5"	"Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1"	"12"	"7"	"12"	"7"	"876"	"100.6"	"5.96"	"2626.64"	"23.51"	"6"	"6"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04959, Pf12066"	"51593"	"ENSG00000087087"	"SRRT"	"A4D2E5; A4D2E6; A6NK22; B4DJL4; B4DZA6; hsa:51593; O95808; Q32MI4; Q6NT74; Q8TDQ5; Q9BWP6; Q9BXP4; Q9BXP5; Q9Y4S4"	"mRNA Splicing - Major Pathway; RNA polymerase II transcribes snRNA genes"	""	"2"	"0"	"360.5"	"468.2"	"1357.8"	"525.8"	"480.5"	"472.5"	"1408.5"	"201.1"	"352.2"	"264.3"	"251.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15372"	"Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1"	"31"	"9"	"17"	"9"	"352"	"39.9"	"6.54"	"3663.76"	"23.49"	"9"	"8"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01398, Pf19445"	"8667"	"ENSG00000147677"	"EIF3H"	"hsa:8667; O15372"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"Translation factors; VEGFA-VEGFR2 signaling; Measles virus infection; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"10"	"0"	"559.9"	"523.1"	"1690.6"	"513.2"	"482.5"	"415.7"	"1725.3"	"214.9"	"318.0"	"267.5"	"284.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P2E9"	"Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5"	"31"	"20"	"25"	"20"	"1410"	"152.4"	"8.60"	"7912.10"	"23.45"	"19"	"6"	"protein metabolism;other metabolic processes;transport"	"other membranes;ER/Golgi;translational apparatus"	"other molecular function"	"Pf05104"	"6238"	"ENSG00000125844"	"RRBP1"	"A0A0A0MRV0; A2A2S6; A6NCN6; hsa:6238; O75300; O75301; Q5W165; Q96SB2; Q9BWP1; Q9H476; Q9P2E9"	"Signaling by ALK fusions and activated point mutants"	"Ectoderm differentiation"	"2"	"0"	"1147.2"	"1127.9"	"2922.1"	"1043.3"	"1072.9"	"943.3"	"4749.5"	"1285.5"	"2066.3"	"1611.5"	"1537.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00299"	"Chloride intracellular channel protein 1 OS=Homo sapiens OX=9606 GN=CLIC1 PE=1 SV=4"	"38"	"8"	"15"	"7"	"241"	"26.9"	"5.17"	"2882.21"	"23.43"	"8"	"7"	"transport;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;mitochondrion;nucleus;other cell component"	"transporter activity"	"Pf13409, Pf13410"	"1192"	"ENSG00000206394; ENSG00000213719; ENSG00000223639; ENSG00000226248; ENSG00000226417; ENSG00000226651; ENSG00000230685"	"CLIC1"	"hsa:1192; O00299; Q15089; Q502X1"	""	"VEGFA-VEGFR2 signaling"	"1"	"1"	"513.3"	"588.5"	"2973.4"	"632.5"	"514.4"	"383.5"	"3655.2"	"320.6"	"406.8"	"331.5"	"321.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62136"	"Serine/threonine-protein phosphatase PP1-alpha catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CA PE=1 SV=1"	"27"	"7"	"12"	"3"	"330"	"37.5"	"6.33"	"1899.53"	"23.39"	"5"	"7"	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00149, Pf16891"	"5499"	"ENSG00000172531"	"PPP1CA"	"A6NNR3; B2R908; hsa:5499; P08129; P20653; P22802; P62136; Q07161"	"Triglyceride catabolism; Circadian Clock; Downregulation of TGF-beta receptor signaling; DARPP-32 events"	"Sphingolipid pathway; Nicotine effect on dopaminergic neurons; Common pathways underlying drug addiction; Focal adhesion; VEGFA-VEGFR2 signaling; Hippo-Merlin signaling dysregulation; Fragile X syndrome; Netrin-UNC5B signaling pathway; Neuroinflammation and glutamatergic signaling"	"13"	"4"	"446.3"	"486.3"	"1435.6"	"535.3"	"453.9"	"351.8"	"1715.5"	"360.3"	"587.2"	"488.3"	"529.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3U8"	"60S ribosomal protein L36 OS=Homo sapiens OX=9606 GN=RPL36 PE=1 SV=3"	"44"	"9"	"17"	"8"	"105"	"12.2"	"11.59"	"4006.17"	"23.22"	"9"	"5"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus"	"other molecular function"	"Pf01158"	"25873"	"ENSG00000130255"	"RPL36"	"B2R4Y1; D6W634; hsa:25873; Q6FIG1; Q9UQF6; Q9Y3U8"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"1"	"1083.1"	"1179.6"	"3596.7"	"1033.1"	"968.4"	"868.0"	"4256.9"	"431.9"	"597.3"	"466.1"	"414.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKK9"	"ADP-sugar pyrophosphatase OS=Homo sapiens OX=9606 GN=NUDT5 PE=1 SV=1"	"36"	"8"	"14"	"8"	"219"	"24.3"	"4.94"	"3337.14"	"23.21"	"8"	"6"	"cell organization and biogenesis;other metabolic processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00293"	"11164"	"ENSG00000165609"	"NUDT5"	"A8K516; hsa:11164; Q6IAG0; Q9UH49; Q9UKK9"	"Phosphate bond hydrolysis by NUDT proteins"	"10q11.21q11.23 copy number variation syndrome"	"2"	"0"	"575.2"	"694.9"	"2134.2"	"669.0"	"670.0"	"612.3"	"2459.9"	"416.2"	"664.5"	"470.9"	"476.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P28066"	"Proteasome subunit alpha type-5 OS=Homo sapiens OX=9606 GN=PSMA5 PE=1 SV=3"	"34"	"5"	"12"	"5"	"241"	"26.4"	"4.79"	"2683.81"	"23.20"	"5"	"5"	"protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	""	"Pf00227, Pf10584"	"5686"	"ENSG00000143106"	"PSMA5"	"B2R8F6; B4E2V4; hsa:5686; P28066; Q3T1C1; Q6IBF7"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"63"	"0"	"167.0"	"180.1"	"733.1"	"174.9"	"129.6"	"82.3"	"747.4"	"147.3"	"165.0"	"142.0"	"160.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H3K6"	"BolA-like protein 2 OS=Homo sapiens OX=9606 GN=BOLA2 PE=1 SV=1"	"62"	"4"	"12"	"4"	"86"	"10.1"	"6.52"	"2595.37"	"23.16"	"4"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01722"	"552900; 654483"	"ENSG00000169627; ENSG00000183336"	"BOLA2; BOLA2B"	"A1L454; A7YDY3; hsa:552900; hsa:654483; Q9H3K6"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	""	"1"	"0"	"392.7"	"597.8"	"2032.4"	"563.9"	"549.2"	"474.2"	"2716.7"	"318.0"	"528.7"	"380.0"	"357.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7L014"	"Probable ATP-dependent RNA helicase DDX46 OS=Homo sapiens OX=9606 GN=DDX46 PE=1 SV=2"	"9"	"8"	"15"	"8"	"1031"	"117.3"	"9.29"	"2869.12"	"23.15"	"8"	"7"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"other membranes;nucleus"	"other molecular function"	"Pf00270, Pf00271"	"9879"	"ENSG00000145833"	"DDX46"	"hsa:9879; O94894; Q7L014; Q96EI0; Q9Y658"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"353.3"	"366.0"	"1283.7"	"334.1"	"296.0"	"256.6"	"1099.2"	"154.2"	"316.3"	"376.7"	"460.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NRV9"	"Heme-binding protein 1 OS=Homo sapiens OX=9606 GN=HEBP1 PE=1 SV=1"	"46"	"6"	"14"	"6"	"189"	"21.1"	"5.80"	"2082.52"	"23.13"	"4"	"6"	"other biological processes"	"non-structural extracellular;other cell component"	"other molecular function"	"Pf04832"	"50865"	"ENSG00000013583"	"HEBP1"	"A8K1G2; hsa:50865; Q9NRV9; Q9Y5Z5"	"G alpha (i) signalling events; Formyl peptide receptors bind formyl peptides and many other ligands"	""	"2"	"0"	"460.9"	"455.3"	"1086.4"	"390.6"	"509.4"	"452.7"	"1598.9"	"462.3"	"623.0"	"487.3"	"497.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43615"	"Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2"	"18"	"6"	"13"	"6"	"452"	"51.3"	"8.32"	"3060.78"	"23.13"	"6"	"6"	"cell organization and biogenesis;transport"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf04280"	"10469"	"ENSG00000104980"	"TIMM44"	"A8K0R9; D6W664; hsa:10469; O43615; Q8N193"	"Mitochondrial protein import"	""	"1"	"0"	"229.3"	"236.4"	"959.8"	"277.2"	"235.4"	"208.0"	"1051.7"	"121.8"	"211.2"	"180.8"	"177.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15459"	"Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1"	"11"	"8"	"14"	"7"	"793"	"88.8"	"5.22"	"2866.02"	"23.12"	"7"	"7"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00240, Pf01805, Pf12230"	"10291"	"ENSG00000099995"	"SF3A1"	"E9PAW1; hsa:10291; Q15459"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"1"	"616.6"	"615.5"	"1935.5"	"625.9"	"564.2"	"545.0"	"1941.8"	"318.8"	"454.1"	"404.4"	"359.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12905"	"Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2"	"21"	"7"	"13"	"7"	"390"	"43.0"	"5.26"	"2835.68"	"23.03"	"7"	"5"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf07528"	"3608"	"ENSG00000143621"	"ILF2"	"A6NDB0; B2R8G7; hsa:3608; Q12905; Q5SR10; Q5SR11; Q7L7R3; Q9BWD4; Q9P1N0"	"Neutrophil degranulation"	"B cell receptor signaling pathway"	"2"	"0"	"937.2"	"948.9"	"3001.2"	"880.1"	"799.6"	"662.1"	"3345.4"	"381.2"	"657.5"	"462.2"	"477.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2Z4"	"Tyrosine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=YARS2 PE=1 SV=2"	"13"	"5"	"12"	"5"	"477"	"53.2"	"8.98"	"2521.15"	"23.02"	"5"	"5"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00579"	"51067"	"ENSG00000139131"	"YARS2"	"D3DUW8; hsa:51067; Q9H817; Q9Y2Z4"	"Mitochondrial tRNA aminoacylation"	"Orexin receptor pathway"	"2"	"0"	"291.4"	"300.0"	"752.5"	"291.8"	"295.4"	"246.1"	"1405.8"	"445.6"	"673.2"	"708.3"	"772.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75937"	"DnaJ homolog subfamily C member 8 OS=Homo sapiens OX=9606 GN=DNAJC8 PE=1 SV=2"	"31"	"6"	"10"	"6"	"253"	"29.8"	"9.06"	"2158.39"	"22.93"	"5"	"5"	""	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00226"	"22826"	"ENSG00000126698; ENSG00000285317"	"DNAJC8"	"B4DUU4; D3DPM0; hsa:22826; O75937; Q6IBA4; Q8N4Z5; Q9P051; Q9P067"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"0"	"467.2"	"456.7"	"1987.3"	"575.7"	"433.7"	"329.6"	"2987.1"	"386.0"	"899.0"	"1238.3"	"2059.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99733"	"Nucleosome assembly protein 1-like 4 OS=Homo sapiens OX=9606 GN=NAP1L4 PE=1 SV=1"	"19"	"8"	"16"	"6"	"375"	"42.8"	"4.69"	"2449.80"	"22.91"	"8"	"8"	"cell organization and biogenesis"	"nucleus;other cell component"	"other molecular function"	"Pf00956"	"4676"	"ENSG00000205531; ENSG00000273562"	"NAP1L4"	"B2R6J4; F5HFY4; hsa:4676; Q99733"	""	""	"0"	"0"	"375.7"	"448.5"	"1348.0"	"401.1"	"376.0"	"315.8"	"1796.4"	"288.3"	"395.3"	"314.1"	"322.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61254"	"60S ribosomal protein L26 OS=Homo sapiens OX=9606 GN=RPL26 PE=1 SV=1"	"38"	"8"	"19"	"1"	"145"	"17.2"	"10.55"	"3177.99"	"22.89"	"8"	"5"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00467, Pf16906"	"6154"	"ENSG00000161970"	"RPL26"	"B2R4F0; D3DTR8; hsa:6154; P61254; Q02877; Q6IPY2"	"Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Peptide chain elongation; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"15"	"10"	"1624.7"	"1752.3"	"5010.0"	"1597.9"	"1543.4"	"1395.0"	"5830.1"	"660.1"	"1102.8"	"830.5"	"653.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P32929"	"Cystathionine gamma-lyase OS=Homo sapiens OX=9606 GN=CTH PE=1 SV=3"	"16"	"5"	"12"	"5"	"405"	"44.5"	"6.70"	"2373.57"	"22.89"	"5"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf01053"	"1491"	"ENSG00000116761"	"CTH"	"B4E1R2; E9PDV0; hsa:1491; P32929; Q53FB3; Q53Y79; Q9H4W7; Q9H4W8"	"Degradation of cysteine and homocysteine; Metabolism of ingested SeMet, Sec, MeSec into H2Se; Cysteine formation from homocysteine"	"Selenium micronutrient network; Vitamin B12 metabolism; Folate metabolism; Trans-sulfuration pathway; Trans-sulfuration, one-carbon metabolism and related pathways; Amino acid metabolism; Methionine metabolism leading to sulfur amino acids and related disorders; Ferroptosis"	"11"	"0"	"243.2"	"294.3"	"910.4"	"290.0"	"271.7"	"221.8"	"992.1"	"148.5"	"226.4"	"159.9"	"176.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14980"	"Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1"	"5"	"4"	"14"	"4"	"1071"	"123.3"	"6.06"	"2723.81"	"22.86"	"4"	"4"	"other metabolic processes;transport;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03810, Pf08389, Pf08767, Pf18777, Pf18784, Pf18787"	"7514"	"ENSG00000082898"	"XPO1"	"A6NL14; A8K1K5; D6W5E2; hsa:7514; O14980; Q63HP8; Q68CP3; Q99433"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; MAPK6/MAPK4 signaling; NPAS4 regulates expression of target genes; Rev-mediated nuclear export of HIV RNA; NEP/NS2 Interacts with the Cellular Export Machinery; Heme signaling; Deactivation of the beta-catenin transactivating complex; Estrogen-dependent nuclear events downstream of ESR-membrane signaling; Downregulation of TGF-beta receptor signaling; HuR (ELAVL1) binds and stabilizes mRNA; Cyclin A/B1/B2 associated events during G2/M transition"	"eIF5A regulation in response to inhibition of the nuclear export system; 22q11.2 copy number variation syndrome"	"18"	"0"	"138.9"	"144.2"	"676.7"	"124.4"	"88.7"	"69.8"	"570.3"	"44.8"	"60.4"	"47.9"	"49.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09493"	"Tropomyosin alpha-1 chain OS=Homo sapiens OX=9606 GN=TPM1 PE=1 SV=2"	"18"	"6"	"15"	"1"	"284"	"32.7"	"4.74"	"2993.02"	"22.83"	"6"	"5"	"cell organization and biogenesis;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00261"	"7168"	"ENSG00000140416"	"TPM1"	"B7Z5T7; D9YZV2; D9YZV3; D9YZV8; hsa:7168; P09493; P09494; P10469; Q6DV89; Q6DV90; Q7Z6L8; Q86W64; Q96IK2; Q9UCI1; Q9UCI2; Q9UCY9; Q9Y427"	"Smooth Muscle Contraction; Striated Muscle Contraction"	"Vitamin D receptor pathway; Striated muscle contraction pathway"	"4"	"0"	"13.2"	"16.5"	"71.5"	"13.3"	"12.4"	"6.5"	"155.1"	"16.7"	"17.8"	"7.5"	"12.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P33991"	"DNA replication licensing factor MCM4 OS=Homo sapiens OX=9606 GN=MCM4 PE=1 SV=5"	"9"	"6"	"13"	"6"	"863"	"96.5"	"6.74"	"1835.15"	"22.71"	"5"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf14551, Pf17207, Pf17855"	"4173"	"ENSG00000104738"	"MCM4"	"hsa:4173; P33991; Q8NEH1; Q99658"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"Cell cycle; Gastric cancer network 1; Retinoblastoma gene in cancer; Ciliary landscape; G1 to S cell cycle control; DNA replication; 10q11.21q11.23 copy number variation syndrome"	"13"	"0"	"665.7"	"705.3"	"2141.2"	"535.1"	"485.1"	"396.0"	"2318.6"	"264.0"	"387.1"	"331.8"	"374.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94826"	"Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1"	"13"	"7"	"13"	"7"	"608"	"67.4"	"7.12"	"2736.04"	"22.59"	"7"	"6"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00515, Pf13181"	"9868"	"ENSG00000154174"	"TOMM70"	"D3DN48; hsa:9868; O94826"	"Ub-specific processing proteases; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Mitochondrial protein import; DDX58/IFIH1-mediated induction of interferon-alpha/beta; SARS-CoV-1 activates/modulates innate immune responses; PINK1-PRKN Mediated Mitophagy"	"Mitochondrial immune response to SARS-CoV-2; SARS-CoV-2 B.1.1.7 variant antagonises innate immune activation; SARS-CoV-2 mitochondrial chronic oxidative stress and endothelial dysfunction"	"9"	"0"	"509.4"	"498.6"	"1787.4"	"495.9"	"465.3"	"383.0"	"1878.5"	"270.5"	"477.1"	"420.6"	"583.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UNX3"	"60S ribosomal protein L26-like 1 OS=Homo sapiens OX=9606 GN=RPL26L1 PE=1 SV=1"	"38"	"8"	"19"	"1"	"145"	"17.2"	"10.55"	"3174.37"	"22.58"	"8"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00467, Pf16906"	"51121"	"ENSG00000037241"	"RPL26L1"	"B3KY82; D3DQM0; hsa:51121; Q9UNX3"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	""	"13"	"0"	"55.9"	"47.3"	"152.2"	"43.4"	"50.6"	"38.6"	"184.8"	"14.0"	"29.6"	"11.9"	"15.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49006"	"MARCKS-related protein OS=Homo sapiens OX=9606 GN=MARCKSL1 PE=1 SV=2"	"35"	"4"	"11"	"4"	"195"	"19.5"	"4.67"	"1692.69"	"22.57"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02063"	"65108"	"ENSG00000175130"	"MARCKSL1"	"D3DPQ0; hsa:65108; P49006; Q5TEE6; Q6NXS5"	""	""	"0"	"0"	"319.2"	"383.5"	"1857.3"	"378.4"	"310.5"	"199.5"	"2011.8"	"196.3"	"274.8"	"226.6"	"251.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99798"	"Aconitate hydratase, mitochondrial OS=Homo sapiens OX=9606 GN=ACO2 PE=1 SV=2"	"11"	"6"	"11"	"6"	"780"	"85.4"	"7.61"	"2031.89"	"22.54"	"5"	"6"	"other metabolic processes;stress response;developmental processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf00330, Pf00694"	"50"	"ENSG00000100412"	"ACO2"	"hsa:50; O75809; Q5JZ41; Q6FHX0; Q8TAQ6; Q99798"	"Citric acid cycle (TCA cycle); Mitochondrial protein import"	"Amino acid metabolism; Metabolic reprogramming in colon cancer; Fluoroacetic acid toxicity; TCA cycle (aka Krebs or citric acid cycle)"	"6"	"0"	"469.8"	"527.4"	"2036.8"	"501.2"	"395.3"	"286.8"	"2057.9"	"233.4"	"426.9"	"306.6"	"279.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99426"	"Tubulin-folding cofactor B OS=Homo sapiens OX=9606 GN=TBCB PE=1 SV=2"	"31"	"6"	"13"	"6"	"244"	"27.3"	"5.15"	"2603.82"	"22.53"	"5"	"6"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf01302, Pf14560"	"1155"	"ENSG00000105254"	"TBCB"	"hsa:1155; O00111; O00674; O14728; Q6FGY5; Q99426"	"Post-chaperonin tubulin folding pathway"	""	"1"	"0"	"235.2"	"247.8"	"1014.7"	"226.2"	"189.6"	"158.2"	"1651.0"	"145.6"	"180.1"	"134.7"	"148.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86V81"	"THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3"	"32"	"4"	"6"	"4"	"257"	"26.9"	"11.15"	"985.63"	"22.41"	"2"	"4"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf13865"	"10189"	""	"ALYREF"	"hsa:10189; O43672; Q86V81"	"mRNA Splicing - Major Pathway; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	""	"7"	"0"	"178.5"	"222.0"	"611.3"	"182.2"	"214.2"	"150.9"	"970.1"	"136.0"	"243.1"	"162.5"	"175.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P83881"	"60S ribosomal protein L36a OS=Homo sapiens OX=9606 GN=RPL36A PE=1 SV=2"	"49"	"9"	"15"	"9"	"106"	"12.4"	"10.58"	"2301.07"	"22.34"	"7"	"8"	"protein metabolism;other metabolic processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;translational apparatus"	"other molecular function"	"Pf00935"	"6173"	"ENSG00000241343"	"RPL36A"	"hsa:6173; P09896; P10661; P83881; Q08ES5; Q5J9I6"	"GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"1632.4"	"1688.7"	"5128.9"	"1607.1"	"1512.7"	"1389.1"	"6301.9"	"569.5"	"916.1"	"661.9"	"581.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95347"	"Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2"	"5"	"6"	"14"	"6"	"1197"	"135.6"	"8.43"	"2804.71"	"22.34"	"6"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02463, Pf06470"	"10592"	"ENSG00000136824"	"SMC2"	"hsa:10592; O95347; Q6IEE0; Q9P1P2"	"Condensation of Prophase Chromosomes; Condensation of Prometaphase Chromosomes"	"Retinoblastoma gene in cancer"	"3"	"0"	"405.1"	"390.3"	"1410.2"	"371.4"	"314.4"	"260.2"	"940.2"	"114.6"	"219.9"	"174.8"	"192.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13492"	"Phosphatidylinositol-binding clathrin assembly protein OS=Homo sapiens OX=9606 GN=PICALM PE=1 SV=2"	"14"	"6"	"12"	"6"	"652"	"70.7"	"7.90"	"2432.00"	"22.20"	"5"	"5"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf07651"	"8301"	"ENSG00000073921"	"PICALM"	"B4DTM3; E9PN05; F8VPG7; hsa:8301; O60700; Q13492; Q4LE54; Q6GMQ6; Q86XZ9"	"Cargo recognition for clathrin-mediated endocytosis; Golgi Associated Vesicle Biogenesis; RND3 GTPase cycle"	""	"4"	"0"	"206.7"	"207.7"	"574.4"	"212.4"	"235.4"	"187.3"	"685.5"	"186.6"	"483.5"	"863.8"	"1211.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49915"	"GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1"	"11"	"5"	"10"	"5"	"693"	"76.7"	"6.87"	"2636.67"	"22.10"	"4"	"4"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf00117, Pf00958, Pf02540"	"8833"	"ENSG00000163655"	"GMPS"	"A8K639; B4DXV7; F8W720; hsa:8833; P49915"	"Purine ribonucleoside monophosphate biosynthesis; Azathioprine ADME"	""	"2"	"0"	"127.3"	"141.6"	"662.1"	"149.0"	"135.8"	"96.9"	"817.5"	"59.0"	"104.8"	"72.1"	"68.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61026"	"Ras-related protein Rab-10 OS=Homo sapiens OX=9606 GN=RAB10 PE=1 SV=1"	"23"	"5"	"14"	"3"	"200"	"22.5"	"8.38"	"2891.64"	"22.00"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00071"	"10890"	"ENSG00000084733"	"RAB10"	"D6W538; hsa:10890; O88386; P61026; Q6IA52; Q9D7X6; Q9H0T3"	"RAB GEFs exchange GTP for GDP on RABs; Neutrophil degranulation; Translocation of SLC2A4 (GLUT4) to the plasma membrane; RAB geranylgeranylation"	"Focal adhesion: PI3K-Akt-mTOR-signaling pathway"	"5"	"2"	"383.4"	"375.5"	"1763.8"	"366.4"	"360.3"	"231.6"	"1505.0"	"170.8"	"222.2"	"156.8"	"132.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15637"	"Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4"	"13"	"7"	"13"	"7"	"639"	"68.3"	"8.98"	"2743.07"	"21.95"	"6"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"translational apparatus;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf00098, Pf16275"	"7536"	"ENSG00000168066"	"SF1"	"B7Z1Q1; C9JJE2; hsa:7536; Q14818; Q14819; Q15637; Q15913; Q8IY00; Q92744; Q92745; Q969H7; Q9BW01; Q9UEI0"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"416.7"	"468.1"	"1348.7"	"455.4"	"468.5"	"394.8"	"1739.7"	"300.4"	"476.8"	"436.2"	"491.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52292"	"Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1"	"15"	"5"	"9"	"5"	"529"	"57.8"	"5.40"	"1758.77"	"21.93"	"4"	"5"	"DNA metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00514, Pf01749, Pf16186"	"3838"	"ENSG00000182481"	"KPNA2"	"B9EJD6; hsa:3838; P52292; Q53YE3; Q6NVW7; Q9BRU5"	"ISG15 antiviral mechanism; NS1 Mediated Effects on Host Pathways; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Estrogen-dependent gene expression; SARS-CoV-1 activates/modulates innate immune responses; Sensing of DNA Double Strand Breaks; CaMK IV-mediated phosphorylation of CREB; CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde"	""	"8"	"0"	"176.7"	"209.0"	"838.6"	"213.2"	"160.5"	"142.4"	"881.4"	"128.6"	"163.6"	"143.2"	"155.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15293"	"Reticulocalbin-1 OS=Homo sapiens OX=9606 GN=RCN1 PE=1 SV=1"	"21"	"6"	"10"	"6"	"331"	"38.9"	"5.00"	"1694.17"	"21.90"	"4"	"6"	"developmental processes"	"ER/Golgi"	"other molecular function"	"Pf13202"	"5954"	"ENSG00000049449"	"RCN1"	"B7Z1M1; D3DR00; hsa:5954; Q15293"	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation"	"VEGFA-VEGFR2 signaling"	"3"	"0"	"880.5"	"993.9"	"3733.2"	"1102.4"	"930.8"	"869.0"	"3662.0"	"345.9"	"663.8"	"492.8"	"511.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62316"	"Small nuclear ribonucleoprotein Sm D2 OS=Homo sapiens OX=9606 GN=SNRPD2 PE=1 SV=1"	"56"	"6"	"12"	"6"	"118"	"13.5"	"9.91"	"2471.10"	"21.89"	"5"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf01423"	"6633"	"ENSG00000125743"	"SNRPD2"	"A8K797; hsa:6633; J3KPM5; P43330; P62316"	"mRNA Splicing - Major Pathway; SARS-CoV-2 modulates host translation machinery; snRNP Assembly; mRNA Splicing - Minor Pathway"	"mRNA processing"	"5"	"0"	"557.9"	"633.8"	"2127.4"	"693.8"	"644.2"	"566.4"	"2069.1"	"187.3"	"372.1"	"255.8"	"294.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P53618"	"Coatomer subunit beta OS=Homo sapiens OX=9606 GN=COPB1 PE=1 SV=3"	"9"	"7"	"13"	"7"	"953"	"107.1"	"6.05"	"2478.95"	"21.81"	"6"	"7"	"transport"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf01602, Pf07718, Pf14806"	"1315"	"ENSG00000129083"	"COPB1"	"D3DQX0; hsa:1315; P53618; Q6GTT7; Q9NTK2; Q9UNW7"	"COPI-dependent Golgi-to-ER retrograde traffic; Neutrophil degranulation; COPI-mediated anterograde transport"	""	"3"	"0"	"257.5"	"268.2"	"1121.9"	"267.0"	"234.8"	"197.9"	"1070.4"	"94.7"	"160.2"	"105.0"	"97.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P53999"	"Activated RNA polymerase II transcriptional coactivator p15 OS=Homo sapiens OX=9606 GN=SUB1 PE=1 SV=3"	"52"	"7"	"13"	"7"	"127"	"14.4"	"9.60"	"2798.28"	"21.73"	"6"	"5"	"RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02229"	"10923"	"ENSG00000113387"	"SUB1"	"hsa:10923; P53999; Q96L29"	""	""	"0"	"0"	"652.0"	"649.3"	"1664.1"	"507.4"	"484.6"	"564.7"	"2541.1"	"779.5"	"490.8"	"425.6"	"440.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16891"	"MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1"	"12"	"9"	"16"	"9"	"758"	"83.6"	"6.48"	"2967.72"	"21.69"	"9"	"7"	"cell organization and biogenesis;other biological processes"	"other membranes;mitochondrion"	""	"Pf09731"	"10989"	"ENSG00000132305"	"IMMT"	"B1H0U5; B2R5N6; hsa:10989; Q14539; Q15092; Q16891; Q68D41; Q69HW5; Q6IBL0; Q7Z3X1; Q8TAJ5; Q9P0V2"	"Cristae formation"	""	"1"	"0"	"708.9"	"721.4"	"2708.1"	"624.6"	"573.9"	"422.6"	"3014.4"	"332.3"	"508.9"	"488.1"	"487.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94903"	"Pyridoxal phosphate homeostasis protein OS=Homo sapiens OX=9606 GN=PLPBP PE=1 SV=1"	"27"	"6"	"13"	"6"	"275"	"30.3"	"7.50"	"2232.96"	"21.68"	"6"	"6"	""	"cytosol;other cell component"	"other molecular function"	"Pf01168"	"11212"	"ENSG00000147471"	"PLPBP"	"hsa:11212; O94903; Q6FI94"	""	""	"0"	"0"	"178.5"	"194.0"	"587.7"	"198.1"	"221.0"	"167.2"	"632.3"	"161.5"	"487.6"	"893.2"	"1289.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62318"	"Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1"	"48"	"4"	"8"	"4"	"126"	"13.9"	"10.32"	"1207.38"	"21.65"	"3"	"4"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01423"	"6634"	"ENSG00000100028"	"SNRPD3"	"B4DJP7; B5BU13; hsa:6634; P43331; P62318"	"mRNA Splicing - Major Pathway; SARS-CoV-2 modulates host translation machinery; snRNP Assembly; RNA Polymerase II Transcription Termination; mRNA Splicing - Minor Pathway; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"mRNA processing"	"8"	"0"	"306.9"	"357.1"	"1290.6"	"320.2"	"292.8"	"237.8"	"1276.2"	"111.0"	"189.6"	"130.9"	"119.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P2Q9"	"Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2"	"5"	"9"	"13"	"9"	"2335"	"273.4"	"8.84"	"2103.86"	"21.57"	"6"	"7"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01398, Pf08082, Pf08083, Pf08084, Pf10596, Pf10597, Pf10598, Pf12134"	"10594"	"ENSG00000174231; ENSG00000274442"	"PRPF8"	"hsa:10594; O14547; O75965; Q6P2Q9"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"mRNA processing"	"3"	"0"	"476.9"	"513.5"	"1833.8"	"464.0"	"440.5"	"343.3"	"1549.6"	"290.4"	"330.3"	"310.1"	"402.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63208"	"S-phase kinase-associated protein 1 OS=Homo sapiens OX=9606 GN=SKP1 PE=1 SV=2"	"53"	"6"	"10"	"6"	"163"	"18.6"	"4.54"	"2129.80"	"21.57"	"5"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf01466, Pf03931"	"6500"	"ENSG00000113558"	"SKP1"	"D3DQ97; D3DQ98; hsa:6500; P34991; P63208; Q8TAY2"	"Nuclear events stimulated by ALK signaling in cancer; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; SCF-beta-TrCP mediated degradation of Emi1; Vpu mediated degradation of CD4; Degradation of beta-catenin by the destruction complex; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; NIK-->noncanonical NF-kB signaling; Orc1 removal from chromatin; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Neddylation; SCF(Skp2)-mediated degradation of p27/p21; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Regulation of PLK1 Activity at G2/M Transition; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Circadian Clock; Cyclin D associated events in G1; Regulation of BACH1 activity; MAP3K8 (TPL2)-dependent MAPK1/3 activation; NOTCH1 Intracellular Domain Regulates Transcription; Prolactin receptor signaling; Iron uptake and transport; Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling"	"Cell cycle; TNF-alpha signaling pathway; Breast cancer pathway; Small cell lung cancer; Notch signaling pathway"	"38"	"0"	"481.2"	"613.0"	"2234.2"	"579.3"	"484.5"	"447.7"	"2243.0"	"305.0"	"444.0"	"326.1"	"349.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13804"	"Electron transfer flavoprotein subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ETFA PE=1 SV=1"	"25"	"6"	"11"	"6"	"333"	"35.1"	"8.38"	"2204.32"	"21.56"	"5"	"6"	"other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf00766, Pf01012"	"2108"	"ENSG00000140374"	"ETFA"	"B4DT43; hsa:2108; P13804; Q53XN3"	"Respiratory electron transport"	""	"1"	"0"	"156.8"	"169.0"	"740.6"	"182.6"	"159.1"	"104.5"	"920.1"	"103.5"	"144.5"	"123.9"	"138.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01081"	"Splicing factor U2AF 35 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF1 PE=1 SV=3"	"27"	"4"	"10"	"4"	"240"	"27.9"	"8.81"	"1551.11"	"21.53"	"2"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00642"	"102724594; 7307"	"ENSG00000160201"	"U2AF1"	"hsa:102724594; hsa:7307; Q01081; Q701P4; Q71RF1"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"mRNA processing"	"5"	"0"	"161.7"	"159.2"	"591.0"	"152.3"	"161.9"	"133.1"	"623.6"	"82.1"	"125.3"	"117.9"	"110.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14566"	"DNA replication licensing factor MCM6 OS=Homo sapiens OX=9606 GN=MCM6 PE=1 SV=1"	"10"	"8"	"13"	"8"	"821"	"92.8"	"5.41"	"2431.47"	"21.45"	"6"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf14551, Pf17207, Pf17855, Pf18263"	"4175"	"ENSG00000076003"	"MCM6"	"B2R6H2; hsa:4175; Q13504; Q14566; Q99859"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"Cell cycle; Retinoblastoma gene in cancer; Ciliary landscape; G1 to S cell cycle control; DNA replication; 10q11.21q11.23 copy number variation syndrome"	"12"	"0"	"634.7"	"739.2"	"2567.1"	"629.0"	"589.8"	"475.1"	"3030.3"	"343.7"	"462.9"	"368.9"	"323.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q52LJ0"	"Protein FAM98B OS=Homo sapiens OX=9606 GN=FAM98B PE=1 SV=2"	"18"	"7"	"12"	"5"	"433"	"45.5"	"8.69"	"2248.94"	"21.21"	"6"	"6"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf10239"	"283742"	"ENSG00000171262"	"FAM98B"	"A8MUW5; hsa:283742; Q52LJ0; Q8N935"	"tRNA processing in the nucleus"	""	"1"	"2"	"464.1"	"481.2"	"1547.4"	"546.6"	"444.4"	"405.0"	"1466.7"	"234.8"	"333.6"	"290.0"	"266.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61353"	"60S ribosomal protein L27 OS=Homo sapiens OX=9606 GN=RPL27 PE=1 SV=2"	"49"	"8"	"15"	"7"	"136"	"15.8"	"10.56"	"2870.47"	"21.17"	"7"	"5"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00467, Pf01777"	"6155"	"ENSG00000131469"	"RPL27"	"hsa:6155; P08526; P61353; Q4G0A9"	"L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"15"	"1"	"1435.2"	"1540.3"	"4356.2"	"1271.1"	"1258.1"	"1051.3"	"5068.5"	"528.5"	"829.4"	"671.6"	"733.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z794"	"Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3"	"7"	"4"	"12"	"1"	"578"	"61.9"	"5.99"	"2058.06"	"21.17"	"4"	"4"	"other biological processes"	"plasma membrane;cytosol;cytoskeleton"	"bone, tooth or skin structural activity"	"Pf00038, Pf16208"	"374454"	"ENSG00000189182"	"KRT77"	"hsa:374454; Q7RTS8; Q7Z794"	"Formation of the cornified envelope"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"P25398"	"40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3"	"60"	"8"	"13"	"8"	"132"	"14.5"	"7.21"	"2422.47"	"21.14"	"5"	"7"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01248"	"6206"	"ENSG00000112306"	"RPS12"	"hsa:6206; P25398; Q76M58"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"1145.5"	"1155.1"	"3507.0"	"1009.4"	"972.6"	"875.3"	"2232.0"	"282.8"	"499.4"	"370.9"	"329.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09651"	"Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5"	"17"	"8"	"21"	"6"	"372"	"38.7"	"9.13"	"5294.99"	"20.98"	"7"	"5"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf11627"	"3178"	"ENSG00000135486"	"HNRNPA1"	"A8K4Z8; hsa:3178; P09651; Q3MIB7; Q6PJZ7"	"mRNA Splicing - Major Pathway; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA; SARS-CoV-1-host interactions; SARS-CoV-1 modulates host translation machinery"	"mRNA processing"	"6"	"0"	"1118.4"	"1167.8"	"3024.8"	"1099.2"	"1013.3"	"892.2"	"4621.4"	"774.0"	"1177.7"	"830.9"	"869.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2S6"	"Translation machinery-associated protein 7 OS=Homo sapiens OX=9606 GN=TMA7 PE=1 SV=1"	"36"	"4"	"15"	"3"	"64"	"7.1"	"9.99"	"2517.41"	"20.89"	"4"	"4"	""	""	""	"Pf09072"	"51372"	"ENSG00000232112"	"TMA7"	"hsa:51372; Q9P052; Q9Y2S6"	""	""	"0"	"2"	"984.7"	"887.9"	"1429.3"	"875.6"	"887.0"	"727.2"	"6142.0"	"4223.9"	"5081.4"	"4395.3"	"5999.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14818"	"Proteasome subunit alpha type-7 OS=Homo sapiens OX=9606 GN=PSMA7 PE=1 SV=1"	"25"	"6"	"13"	"6"	"248"	"27.9"	"8.46"	"2808.83"	"20.88"	"6"	"5"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00227, Pf10584"	"5688"	"ENSG00000101182"	"PSMA7"	"B2R515; hsa:5688; O14818; Q5JXJ2; Q9BR53; Q9H4K5; Q9UEU8"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"62"	"0"	"639.2"	"651.9"	"2631.6"	"626.0"	"412.9"	"356.4"	"2536.8"	"480.7"	"528.8"	"484.4"	"544.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P10606"	"Cytochrome c oxidase subunit 5B, mitochondrial OS=Homo sapiens OX=9606 GN=COX5B PE=1 SV=2"	"51"	"7"	"12"	"7"	"129"	"13.7"	"8.81"	"2383.53"	"20.86"	"6"	"6"	"other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf01215"	"1329"	"ENSG00000135940"	"COX5B"	"hsa:1329; P10606; Q53YB7; Q96J18; Q99610"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex IV assembly"	"6"	"0"	"560.2"	"770.4"	"2753.1"	"651.2"	"603.5"	"440.3"	"3397.5"	"444.0"	"615.8"	"439.1"	"430.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75663"	"TIP41-like protein OS=Homo sapiens OX=9606 GN=TIPRL PE=1 SV=2"	"27"	"5"	"9"	"5"	"272"	"31.4"	"5.91"	"1180.12"	"20.67"	"3"	"5"	"stress response;signal transduction;other biological processes"	"cytosol"	""	"Pf04176"	"261726"	"ENSG00000143155"	"TIPRL"	"B2R8V3; hsa:261726; O75663; Q5HYB2; Q8IZ86"	""	"Ciliary landscape"	"1"	"0"	"158.4"	"247.5"	"738.0"	"248.8"	"246.5"	"215.1"	"929.0"	"176.0"	"294.1"	"255.8"	"411.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09429"	"High mobility group protein B1 OS=Homo sapiens OX=9606 GN=HMGB1 PE=1 SV=3"	"39"	"7"	"13"	"7"	"215"	"24.9"	"5.74"	"2950.17"	"20.62"	"7"	"6"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00505, Pf09011"	"3146"	"ENSG00000189403"	"HMGB1"	"A5D8W9; hsa:3146; P09429; Q14321; Q5T7C3; Q6IBE1"	"ER-Phagosome pathway; Neutrophil degranulation; MyD88 deficiency (TLR2/4); IRAK4 deficiency (TLR2/4); Regulation of TLR by endogenous ligand; Apoptosis induced DNA fragmentation; TAK1-dependent IKK and NF-kappa-B activation  ; TRAF6 mediated NF-kB activation; Pyroptosis; Advanced glycosylation endproduct receptor signaling"	"Retinoblastoma gene in cancer; VEGFA-VEGFR2 signaling; Supression of HMGB1 mediated inflammation by THBD; Base excision repair; DNA repair pathways, full network; Pleural mesothelioma; Clock-controlled autophagy in bone metabolism; Autophagy in pancreatic ductal adenocarcinoma; DNA damage response (only ATM dependent)"	"20"	"0"	"1291.7"	"1209.5"	"5315.9"	"1317.4"	"777.9"	"781.9"	"2822.0"	"436.7"	"837.1"	"721.5"	"637.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5T8P6"	"RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3"	"6"	"5"	"12"	"5"	"1007"	"113.5"	"9.16"	"2404.64"	"20.56"	"5"	"5"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf01480"	"64062"	"ENSG00000139746"	"RBM26"	"B4DZE0; hsa:64062; Q2NKM2; Q2NKQ2; Q5CZH8; Q5T8P5; Q5T8P6; Q5T8P8; Q5U5P5; Q5W0G7; Q8N3H5; Q96K92; Q96SZ3; Q9H2F8; Q9H7F9; Q9P1G7"	""	""	"0"	"0"	"300.7"	"311.0"	"1087.5"	"314.7"	"303.5"	"252.1"	"1480.7"	"209.7"	"400.7"	"285.5"	"294.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P12004"	"Proliferating cell nuclear antigen OS=Homo sapiens OX=9606 GN=PCNA PE=1 SV=1"	"35"	"8"	"13"	"8"	"261"	"28.8"	"4.69"	"2334.94"	"20.55"	"6"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00705, Pf02747"	"5111"	"ENSG00000132646"	"PCNA"	"B2R897; D3DW02; hsa:5111; P12004"	"HDR through Homologous Recombination (HRR); E3 ubiquitin ligases ubiquitinate target proteins; SUMOylation of DNA replication proteins; Termination of translesion DNA synthesis; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; G1/S-Specific Transcription; Recognition of DNA damage by PCNA-containing replication complex; Transcription of E2F targets under negative control by DREAM complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Polymerase switching on the C-strand of the telomere; Polymerase switching; Removal of the Flap Intermediate; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"Cell cycle; Retinoblastoma gene in cancer; Primary focal segmental glomerulosclerosis (FSGS); Oxidative damage response; EGF/EGFR signaling pathway; G1 to S cell cycle control; DNA replication; Hepatitis B infection; Base excision repair; Nucleotide excision repair; 7q11.23 copy number variation syndrome; DNA repair pathways, full network; 16p11.2 proximal deletion syndrome; p53 transcriptional gene network; Nucleotide excision repair in xeroderma pigmentosum ; Urotensin-II-mediated signaling pathway; DNA mismatch repair; 10q11.21q11.23 copy number variation syndrome; A network map of Macrophage-stimulating protein (MSP) signaling"	"45"	"0"	"646.3"	"841.5"	"4145.8"	"783.5"	"655.5"	"579.0"	"5464.6"	"542.5"	"680.7"	"560.4"	"499.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P26358"	"DNA (cytosine-5)-methyltransferase 1 OS=Homo sapiens OX=9606 GN=DNMT1 PE=1 SV=2"	"5"	"7"	"13"	"7"	"1616"	"183.1"	"7.75"	"2587.64"	"20.43"	"7"	"6"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00145, Pf01426, Pf02008, Pf06464, Pf12047"	"1786"	"ENSG00000130816"	"DNMT1"	"A0AV63; B7ZLW6; hsa:1786; P26358; Q9UHG5; Q9ULA2; Q9UMZ6"	"SUMOylation of DNA methylation proteins; NoRC negatively regulates rRNA expression; PRC2 methylates histones and DNA; Defective pyroptosis; DNA methylation"	"Trans-sulfuration pathway; One-carbon metabolism; Retinoblastoma gene in cancer; Hematopoietic stem cell gene regulation by GABP alpha/beta complex; MTHFR deficiency"	"10"	"0"	"168.0"	"157.3"	"457.4"	"158.6"	"164.1"	"131.5"	"638.7"	"126.7"	"207.8"	"193.9"	"170.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NVI7"	"ATPase family AAA domain-containing protein 3A OS=Homo sapiens OX=9606 GN=ATAD3A PE=1 SV=2"	"13"	"7"	"10"	"2"	"634"	"71.3"	"8.98"	"1547.67"	"20.35"	"4"	"6"	"cell organization and biogenesis;stress response;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf00004, Pf12037"	"55210"	"ENSG00000197785"	"ATAD3A"	"B3KPB3; D2K8Q1; G3V1I6; hsa:55210; Q5SV23; Q8N275; Q96A50; Q9NVI7"	""	"1p36 copy number variation syndrome"	"1"	"0"	"33.9"	"36.5"	"105.0"	"24.0"	"24.0"	"20.3"	"86.6"	"9.3"	"24.3"	"14.5"	"16.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P0DN79"	"Cystathionine beta-synthase-like protein OS=Homo sapiens OX=9606 GN=CBSL PE=1 SV=1"	"14"	"7"	"15"	"7"	"551"	"60.5"	"6.65"	"2663.36"	"20.35"	"6"	"6"	"DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00291, Pf00571"	"102724560; 875"	"ENSG00000160200"	"CBS"	"B2R993; D3DSK4; hsa:102724560; hsa:875; P35520; Q99425; Q9BWC5"	"Metabolism of ingested SeMet, Sec, MeSec into H2Se; Cysteine formation from homocysteine"	"Selenium micronutrient network; Vitamin B12 metabolism; Folate-alcohol and cancer pathway hypotheses; Folate metabolism; Trans-sulfuration pathway; Trans-sulfuration, one-carbon metabolism and related pathways; Vitamin D receptor pathway; Amino acid metabolism; Methionine metabolism leading to sulfur amino acids and related disorders; Ferroptosis; Ciliary landscape"	"13"	"0"	"288.1"	"310.2"	"1593.9"	"317.0"	"307.5"	"240.9"	"2252.2"	"134.8"	"207.8"	"156.0"	"138.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15843"	"NEDD8 OS=Homo sapiens OX=9606 GN=NEDD8 PE=1 SV=1"	"42"	"3"	"10"	"3"	"81"	"9.1"	"8.43"	"2119.93"	"20.34"	"3"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00240"	"4738"	"ENSG00000129559; ENSG00000285246"	"NEDD8"	"hsa:4738; Q15843; Q3SXN8; Q6LES6"	"Cargo recognition for clathrin-mediated endocytosis; UCH proteinases; Neddylation; Iron uptake and transport; TGF-beta receptor signaling activates SMADs"	"EGF/EGFR signaling pathway; 2q37 copy number variation syndrome"	"7"	"0"	"282.5"	"322.2"	"1446.8"	"320.9"	"281.9"	"199.4"	"1952.2"	"183.7"	"229.8"	"172.5"	"126.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46778"	"60S ribosomal protein L21 OS=Homo sapiens OX=9606 GN=RPL21 PE=1 SV=2"	"46"	"8"	"16"	"8"	"160"	"18.6"	"10.49"	"3392.17"	"20.34"	"8"	"5"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;other cell component"	"other molecular function"	"Pf01157"	"6144"	"ENSG00000122026"	"RPL21"	"hsa:6144; P46778; Q16699"	"SRP-dependent cotranslational protein targeting to membrane; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"1166.8"	"1267.7"	"3611.0"	"1158.8"	"1102.9"	"1008.2"	"3986.1"	"475.6"	"799.6"	"645.4"	"657.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16543"	"Hsp90 co-chaperone Cdc37 OS=Homo sapiens OX=9606 GN=CDC37 PE=1 SV=1"	"18"	"6"	"9"	"6"	"378"	"44.4"	"5.25"	"1535.33"	"20.28"	"4"	"5"	"stress response;transport;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity;other molecular function"	"Pf03234, Pf08564, Pf08565"	"11140"	"ENSG00000105401"	"CDC37"	"hsa:11140; Q16543; Q53YA2"	"RHOBTB2 GTPase cycle; Regulation of necroptotic cell death; Downregulation of ERBB2 signaling; Signaling by ERBB2 KD Mutants; Signaling by ERBB2 TMD/JMD mutants; Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; Constitutive Signaling by EGFRvIII; Signaling by ERBB2 ECD mutants; Constitutive Signaling by Overexpressed ERBB2; Drug-mediated inhibition of ERBB2 signaling; Resistance of ERBB2 KD mutants to trastuzumab; Resistance of ERBB2 KD mutants to sapitinib; Resistance of ERBB2 KD mutants to tesevatinib; Resistance of ERBB2 KD mutants to neratinib; Resistance of ERBB2 KD mutants to osimertinib; Resistance of ERBB2 KD mutants to afatinib; Resistance of ERBB2 KD mutants to AEE788; Resistance of ERBB2 KD mutants to lapatinib; Drug resistance in ERBB2 TMD/JMD mutants"	"TNF-alpha signaling pathway; Aryl hydrocarbon receptor pathway; Aryl hydrocarbon receptor pathway; Nuclear receptors meta-pathway; Interactions between LOXL4 and oxidative stress pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway"	"27"	"0"	"307.0"	"357.4"	"1593.5"	"440.4"	"379.7"	"311.5"	"1679.1"	"191.4"	"347.5"	"255.5"	"206.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49589"	"Cysteine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=CARS1 PE=1 SV=3"	"13"	"8"	"14"	"8"	"748"	"85.4"	"6.76"	"2344.28"	"20.17"	"6"	"8"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01406"	"833"	"ENSG00000110619; ENSG00000278191"	"CARS1"	"hsa:833; P49589; Q53XI8; Q5HYE4; Q9HD24; Q9HD25"	"Cytosolic tRNA aminoacylation; Signaling by ALK fusions and activated point mutants"	""	"2"	"0"	"185.0"	"198.5"	"770.7"	"199.0"	"163.6"	"120.4"	"684.9"	"85.5"	"138.2"	"118.1"	"125.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30566"	"Adenylosuccinate lyase OS=Homo sapiens OX=9606 GN=ADSL PE=1 SV=2"	"20"	"6"	"9"	"6"	"484"	"54.9"	"7.11"	"1308.55"	"20.13"	"4"	"5"	"other metabolic processes;stress response;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00206, Pf10397"	"158"	"ENSG00000239900"	"ADSL"	"B0QY76; hsa:158; O75495; P30566; Q5TI34"	"Purine ribonucleoside monophosphate biosynthesis"	""	"1"	"0"	"231.9"	"229.1"	"700.1"	"280.1"	"292.9"	"235.4"	"915.2"	"195.3"	"289.8"	"224.8"	"193.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P78406"	"mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1"	"16"	"5"	"10"	"5"	"368"	"40.9"	"7.83"	"2065.81"	"20.09"	"5"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00400"	"8480"	"ENSG00000101146"	"RAE1"	"A8K882; hsa:8480; O15306; P78406; Q3SYL7; Q5TCH8; Q6V708; Q9H100; Q9NQM6"	"HCMV Early Events; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; HCMV Late Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"IL-18 signaling pathway; SARS-CoV-2 innate immunity evasion and cell-specific immune response"	"30"	"0"	"453.3"	"558.9"	"1416.8"	"628.4"	"629.0"	"559.8"	"1888.5"	"418.6"	"844.3"	"956.1"	"1507.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BSD7"	"Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1"	"33"	"6"	"11"	"6"	"190"	"20.7"	"9.54"	"2098.53"	"20.00"	"5"	"6"	""	""	"other molecular function"	"Pf03266"	"84284"	"ENSG00000135778"	"NTPCR"	"hsa:84284; Q9BSD7"	""	""	"0"	"0"	"208.0"	"230.1"	"602.0"	"197.1"	"226.8"	"156.3"	"998.1"	"300.4"	"501.3"	"673.9"	"1474.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y697"	"Cysteine desulfurase, mitochondrial OS=Homo sapiens OX=9606 GN=NFS1 PE=1 SV=3"	"12"	"5"	"10"	"5"	"457"	"50.2"	"8.31"	"2337.95"	"19.92"	"4"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf00266"	"9054"	"ENSG00000244005"	"NFS1"	"B3KMA5; B4DXK9; E1P5R8; F5GYK5; hsa:9054; Q6P0L8; Q9NTZ5; Q9Y481; Q9Y697"	""	"Iron-sulfur cluster biogenesis"	"1"	"0"	"139.4"	"212.3"	"513.3"	"169.2"	"182.2"	"150.2"	"691.3"	"218.7"	"465.7"	"608.6"	"861.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A0A0B4J2D5"	"Glutamine amidotransferase-like class 1 domain-containing protein 3B, mitochondrial OS=Homo sapiens OX=9606 GN=GATD3B PE=1 SV=1"	"29"	"5"	"7"	"5"	"268"	"28.1"	"8.27"	"713.98"	"19.83"	"2"	"5"	""	"mitochondrion"	""	""	"8209"	""	"GATD3B"	"A0A0B4J2D5; A6NFJ6; A6NJY7; hsa:8209; O00650; O00660; O15011; O15012; P30042; P55346; P78474; Q92505; Q92507"	""	"Gastric cancer network 1"	"1"	"0"	"207.9"	"228.1"	"1022.7"	"253.7"	"207.6"	"173.0"	"1416.5"	"138.3"	"194.4"	"152.4"	"147.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13561"	"Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4"	"14"	"5"	"10"	"5"	"401"	"44.2"	"5.21"	"1983.52"	"19.74"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf04912"	"10540"	"ENSG00000175203"	"DCTN2"	"B2RBK5; hsa:10540; Q13561; Q86YN2; Q9BW17"	"MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Recruitment of NuMA to mitotic centrosomes; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	""	"11"	"0"	"491.5"	"584.4"	"2018.5"	"519.3"	"477.0"	"386.1"	"1965.3"	"200.5"	"315.3"	"263.7"	"246.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08758"	"Annexin A5 OS=Homo sapiens OX=9606 GN=ANXA5 PE=1 SV=2"	"22"	"6"	"12"	"6"	"320"	"35.9"	"5.05"	"2376.96"	"19.68"	"6"	"6"	"stress response;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00191"	"308"	"ENSG00000164111"	"ANXA5"	"D3DNW7; hsa:308; P08758; Q6FHB3; Q6FI16; Q8WV69; Q9UDH9"	"Platelet degranulation"	"Apoptosis-related network due to altered Notch3 in ovarian cancer; Interactions between LOXL4 and oxidative stress pathway; Prostaglandin synthesis and regulation"	"4"	"0"	"393.6"	"454.3"	"2919.0"	"501.5"	"427.2"	"289.8"	"3528.7"	"257.1"	"351.1"	"211.0"	"142.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P27694"	"Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2"	"16"	"7"	"10"	"7"	"616"	"68.1"	"7.21"	"2402.81"	"19.64"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01336, Pf04057, Pf08646, Pf16900"	"6117"	"ENSG00000132383"	"RPA1"	"A8K0Y9; hsa:6117; P27694; Q59ES9"	"SUMOylation of DNA damage response and repair proteins; Fanconi Anemia Pathway; Regulation of HSF1-mediated heat shock response; Regulation of TP53 Activity through Phosphorylation; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Meiotic recombination; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; HSF1 activation; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Removal of the Flap Intermediate; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"Homologous recombination; Retinoblastoma gene in cancer; ATR signaling; G1 to S cell cycle control; DNA replication; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"39"	"0"	"242.3"	"270.6"	"1207.9"	"306.7"	"324.8"	"251.9"	"1652.3"	"152.5"	"279.0"	"158.3"	"159.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UII2"	"ATPase inhibitor, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5IF1 PE=1 SV=1"	"25"	"5"	"13"	"5"	"106"	"12.2"	"9.35"	"1956.21"	"19.62"	"4"	"5"	"cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"mitochondrion;other cell component"	"enzyme regulator activity;other molecular function"	"Pf04568"	"93974"	"ENSG00000130770; ENSG00000285390"	"ATP5IF1"	"hsa:93974; Q5JXL8; Q6IAQ7; Q9BSL9; Q9UII2"	""	"Electron transport chain: OXPHOS system in mitochondria"	"1"	"0"	"811.0"	"1225.6"	"3180.2"	"1144.3"	"1050.3"	"974.9"	"3311.8"	"1030.1"	"1675.6"	"1384.6"	"1758.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61163"	"Alpha-centractin OS=Homo sapiens OX=9606 GN=ACTR1A PE=1 SV=1"	"17"	"5"	"8"	"4"	"376"	"42.6"	"6.64"	"1304.19"	"19.59"	"3"	"5"	"transport"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00022"	"10121"	"ENSG00000138107"	"ACTR1A"	"B2R6B0; hsa:10121; P42024; P61163"	"COPI-mediated anterograde transport; MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-independent Golgi-to-ER retrograde traffic; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	""	"11"	"0"	"341.6"	"352.8"	"1107.6"	"309.9"	"285.6"	"235.0"	"1262.4"	"206.8"	"289.6"	"221.5"	"211.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15370"	"Elongin-B OS=Homo sapiens OX=9606 GN=ELOB PE=1 SV=1"	"53"	"6"	"11"	"6"	"118"	"13.1"	"4.88"	"1684.34"	"19.57"	"5"	"6"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00240"	"6923"	"ENSG00000103363"	"ELOB"	"B7WPD3; hsa:6923; Q15370"	"Regulation of expression of SLITs and ROBOs; Antigen processing: Ubiquitination & Proteasome degradation; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Vif-mediated degradation of APOBEC3G; Neddylation; Inactivation of CSF3 (G-CSF) signaling; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes"	"Dual hijack model of Vif in HIV infection; Type 2 papillary renal cell carcinoma; Hijack of ubiquitination by SARS-CoV-2; Modulators of TCR signaling and T cell activation"	"21"	"0"	"454.2"	"690.9"	"2209.0"	"734.5"	"737.5"	"701.4"	"2615.1"	"549.0"	"888.3"	"656.5"	"718.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07108"	"Acyl-CoA-binding protein OS=Homo sapiens OX=9606 GN=DBI PE=1 SV=2"	"34"	"2"	"10"	"2"	"87"	"10.0"	"6.57"	"2799.30"	"19.54"	"2"	"2"	"other metabolic processes;other biological processes"	"ER/Golgi;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00887"	"1622"	"ENSG00000155368"	"DBI"	"B8ZWD2; B8ZWD6; B8ZWD7; hsa:1622; P07108; P08869; Q4VWZ6; Q53SQ7; Q6IB48; Q9UCI8"	"Mitochondrial Fatty Acid Beta-Oxidation"	"Sterol regulatory element-binding proteins (SREBP) signaling; PPAR-alpha pathway; Nuclear receptors meta-pathway; PPAR signaling pathway; Fatty acid transporters"	"6"	"0"	"150.3"	"208.0"	"2446.8"	"251.9"	"214.5"	"152.1"	"5224.1"	"181.8"	"226.2"	"154.3"	"143.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2R9"	"28S ribosomal protein S7, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS7 PE=1 SV=2"	"31"	"6"	"10"	"6"	"242"	"28.1"	"9.99"	"1405.93"	"19.53"	"4"	"6"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00177"	"51081"	"ENSG00000125445"	"MRPS7"	"B2R9N5; hsa:51081; Q53GD6; Q9Y2R9"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"181.8"	"181.6"	"592.5"	"187.9"	"196.6"	"171.0"	"613.2"	"89.8"	"122.0"	"113.1"	"107.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62277"	"40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2"	"45"	"8"	"16"	"8"	"151"	"17.2"	"10.54"	"3440.01"	"19.46"	"8"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00312, Pf08069"	"6207"	"ENSG00000110700"	"RPS13"	"B2R549; hsa:6207; P19116; P62277; Q02546; Q29200; Q498Y0"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"2394.2"	"2635.2"	"7682.9"	"2163.3"	"1845.9"	"1788.7"	"6652.2"	"686.1"	"955.5"	"693.7"	"721.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6PKG0"	"La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2"	"7"	"7"	"12"	"7"	"1096"	"123.4"	"8.82"	"1731.41"	"19.40"	"5"	"7"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf05383"	"23367"	"ENSG00000155506"	"LARP1"	"hsa:23367; O94836; Q6PKG0; Q8N4M2; Q8NB73; Q9UFD7"	"SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"Perturbations to host-cell autophagy, induced by SARS-CoV-2 proteins; SARS-CoV-2 innate immunity evasion and cell-specific immune response; Network map of SARS-CoV-2 signaling pathway"	"4"	"0"	"638.4"	"638.6"	"2088.3"	"599.0"	"521.1"	"468.7"	"1815.9"	"217.4"	"390.7"	"280.7"	"281.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49720"	"Proteasome subunit beta type-3 OS=Homo sapiens OX=9606 GN=PSMB3 PE=1 SV=2"	"28"	"4"	"10"	"4"	"205"	"22.9"	"6.55"	"2221.81"	"19.32"	"4"	"4"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf00227"	"5691"	"ENSG00000275903; ENSG00000277791"	"PSMB3"	"hsa:5691; P31147; P49720; Q0P6J7; Q96E27"	"Antigen processing: Ubiquitination & Proteasome degradation; Regulation of expression of SLITs and ROBOs; FCERI mediated NF-kB activation; Downstream TCR signaling; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"62"	"0"	"259.4"	"298.8"	"1201.0"	"312.8"	"191.0"	"169.7"	"931.3"	"220.2"	"290.4"	"267.0"	"258.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55795"	"Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1"	"15"	"6"	"13"	"1"	"449"	"49.2"	"6.30"	"2187.38"	"19.32"	"5"	"5"	"other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf00076, Pf08080"	"3188"	"ENSG00000126945"	"HNRNPH2"	"A1L400; hsa:3188; P55795; Q9HHA7"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"mRNA processing"	"3"	"0"	"24.9"	"28.9"	"109.3"	"32.5"	"32.6"	"20.3"	"99.8"	"19.1"	"32.7"	"17.2"	"22.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99584"	"Protein S100-A13 OS=Homo sapiens OX=9606 GN=S100A13 PE=1 SV=1"	"31"	"3"	"9"	"3"	"98"	"11.5"	"6.16"	"1596.14"	"19.28"	"2"	"3"	"transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01023"	"6284"	"ENSG00000189171"	"S100A13"	"hsa:6284; Q52PI9; Q6FGF8; Q99584"	""	""	"0"	"0"	"236.8"	"242.4"	"503.5"	"237.2"	"206.0"	"161.0"	"601.3"	"136.7"	"375.0"	"686.4"	"1766.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5T9A4"	"ATPase family AAA domain-containing protein 3B OS=Homo sapiens OX=9606 GN=ATAD3B PE=1 SV=1"	"12"	"7"	"10"	"2"	"648"	"72.5"	"9.20"	"1451.63"	"19.27"	"4"	"6"	"cell organization and biogenesis"	"plasma membrane;other membranes;mitochondrion"	"other molecular function"	"Pf00004, Pf12037"	"83858"	"ENSG00000160072"	"ATAD3B"	"A8K3H1; hsa:83858; Q5T9A4; Q6ZRB5; Q9BUK4; Q9ULE7"	"Neutrophil degranulation"	"1p36 copy number variation syndrome"	"2"	"5"	"367.1"	"392.7"	"1301.4"	"321.3"	"310.9"	"249.6"	"1509.6"	"168.5"	"271.6"	"186.0"	"196.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P33240"	"Cleavage stimulation factor subunit 2 OS=Homo sapiens OX=9606 GN=CSTF2 PE=1 SV=1"	"13"	"5"	"10"	"5"	"577"	"60.9"	"6.83"	"1386.11"	"19.08"	"3"	"5"	"other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf14304, Pf14327"	"1478"	"ENSG00000101811"	"CSTF2"	"hsa:1478; P33240; Q5H951; Q6LA74; Q8N502"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; tRNA processing in the nucleus; Processing of Intronless Pre-mRNAs"	"mRNA processing"	"6"	"0"	"483.3"	"549.0"	"1953.9"	"487.4"	"460.2"	"387.1"	"2302.2"	"349.9"	"642.4"	"492.1"	"566.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5S9"	"RNA-binding protein 8A OS=Homo sapiens OX=9606 GN=RBM8A PE=1 SV=1"	"17"	"2"	"9"	"2"	"174"	"19.9"	"5.72"	"2871.10"	"19.06"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"9939"	"ENSG00000265241"	"RBM8A"	"B3KQI9; hsa:9939; Q6FHD1; Q6IQ40; Q9GZX8; Q9NZI4; Q9Y5S9"	"Regulation of expression of SLITs and ROBOs; mRNA Splicing - Major Pathway; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript"	""	"6"	"0"	"131.8"	"143.1"	"515.7"	"129.2"	"125.2"	"88.0"	"677.9"	"82.5"	"121.1"	"68.8"	"82.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46060"	"Ran GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RANGAP1 PE=1 SV=1"	"13"	"7"	"13"	"7"	"587"	"63.5"	"4.68"	"2444.73"	"19.05"	"7"	"6"	"protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf07834, Pf13516"	"5905"	"ENSG00000100401"	"RANGAP1"	"hsa:5905; P46060; Q96JJ2"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Rev-mediated nuclear export of HIV RNA; SUMOylation of DNA replication proteins; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Postmitotic nuclear pore complex (NPC) reformation; SUMOylation of nuclear envelope proteins"	"22q11.2 copy number variation syndrome; IL-18 signaling pathway"	"12"	"0"	"512.4"	"504.1"	"1733.1"	"450.9"	"357.1"	"319.6"	"1796.0"	"237.1"	"303.3"	"273.4"	"272.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P28838"	"Cytosol aminopeptidase OS=Homo sapiens OX=9606 GN=LAP3 PE=1 SV=3"	"14"	"5"	"9"	"5"	"519"	"56.1"	"7.93"	"1473.39"	"19.03"	"4"	"5"	"protein metabolism"	"other cell component"	"other molecular function"	"Pf00883, Pf02789"	"51056"	"ENSG00000002549"	"LAP3"	"B3KMQ3; hsa:51056; P28838; Q6IAM6; Q6P0L6; Q9UQE3"	""	""	"0"	"0"	"162.2"	"184.0"	"727.6"	"155.4"	"168.7"	"115.1"	"959.8"	"106.4"	"149.4"	"115.1"	"105.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y383"	"Putative RNA-binding protein Luc7-like 2 OS=Homo sapiens OX=9606 GN=LUC7L2 PE=1 SV=2"	"17"	"6"	"11"	"6"	"392"	"46.5"	"10.01"	"2240.94"	"18.99"	"6"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03194"	"51631"	"ENSG00000146963"	"LUC7L2"	"B7Z500; hsa:51631; Q8IUP9; Q9NVL3; Q9NVN7; Q9UQN1; Q9Y383"	""	""	"0"	"0"	"434.2"	"401.3"	"1810.8"	"381.8"	"347.9"	"258.3"	"1894.4"	"184.7"	"283.5"	"257.7"	"261.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15691"	"Microtubule-associated protein RP/EB family member 1 OS=Homo sapiens OX=9606 GN=MAPRE1 PE=1 SV=3"	"28"	"6"	"10"	"5"	"268"	"30.0"	"5.14"	"1997.95"	"18.95"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf03271"	"22919"	"ENSG00000101367"	"MAPRE1"	"B2R6I7; E1P5M8; hsa:22919; Q15691; Q3KQS8"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; Anchoring of the basal body to the plasma membrane; The role of GTSE1 in G2/M progression after G2 checkpoint; Recruitment of NuMA to mitotic centrosomes; EML4 and NUDC in mitotic spindle formation; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; AURKA Activation by TPX2; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"Microtubule cytoskeleton regulation"	"15"	"1"	"546.4"	"627.4"	"2546.9"	"610.9"	"476.0"	"361.7"	"2990.5"	"309.6"	"399.6"	"340.9"	"398.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62750"	"60S ribosomal protein L23a OS=Homo sapiens OX=9606 GN=RPL23A PE=1 SV=1"	"49"	"8"	"16"	"8"	"156"	"17.7"	"10.45"	"4002.81"	"18.90"	"8"	"6"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00276, Pf03939"	"6147"	"ENSG00000198242"	"RPL23A"	"B2R5B2; hsa:6147; P29316; P39024; P62750; Q92774"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"1392.7"	"1380.6"	"4214.7"	"1167.3"	"1160.3"	"974.0"	"4483.7"	"368.8"	"652.6"	"529.8"	"624.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5B9"	"FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1"	"10"	"7"	"12"	"7"	"1047"	"119.8"	"5.66"	"2249.70"	"18.89"	"5"	"6"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus"	"other molecular function"	"Pf00557, Pf08512, Pf08644, Pf14826"	"11198"	"ENSG00000092201"	"SUPT16H"	"hsa:11198; Q6GMT8; Q6P2F1; Q6PJM1; Q9NRX0; Q9Y5B9"	"Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; Regulation of TP53 Activity through Phosphorylation"	""	"12"	"0"	"446.3"	"474.1"	"1881.5"	"397.3"	"338.3"	"304.6"	"889.5"	"128.3"	"222.7"	"177.9"	"156.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60841"	"Eukaryotic translation initiation factor 5B OS=Homo sapiens OX=9606 GN=EIF5B PE=1 SV=4"	"5"	"4"	"7"	"4"	"1220"	"138.7"	"5.49"	"1380.04"	"18.89"	"3"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03144, Pf11987"	"9669"	"ENSG00000158417"	"EIF5B"	"hsa:9669; O60841; O95805; Q53RV7; Q53SI8; Q9UF81; Q9UMN7"	"GTP hydrolysis and joining of the 60S ribosomal subunit"	"Translation factors; Ciliary landscape"	"3"	"0"	"329.8"	"302.3"	"1041.5"	"301.7"	"286.5"	"230.5"	"757.2"	"126.1"	"231.2"	"204.7"	"203.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WUM4"	"Programmed cell death 6-interacting protein OS=Homo sapiens OX=9606 GN=PDCD6IP PE=1 SV=1"	"10"	"8"	"13"	"8"	"868"	"96.0"	"6.52"	"2346.65"	"18.89"	"7"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"non-structural extracellular;plasma membrane;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf03097, Pf13949"	"10015"	"ENSG00000170248"	"PDCD6IP"	"C5MQH7; E9PFU1; hsa:10015; Q6NUS1; Q8WUM4; Q9BX86; Q9NUN0; Q9P2H2; Q9UKL5"	"Budding and maturation of HIV virion; Regulation of necroptotic cell death; Uptake and function of anthrax toxins"	"Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells"	"5"	"0"	"476.9"	"560.5"	"3090.0"	"522.5"	"445.4"	"323.1"	"3390.8"	"212.9"	"308.1"	"247.5"	"233.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y266"	"Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1"	"16"	"6"	"12"	"6"	"331"	"38.2"	"5.38"	"2510.05"	"18.85"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf04969, Pf14050, Pf16273"	"10726"	"ENSG00000090273"	"NUDC"	"hsa:10726; Q5QP31; Q5QP35; Q9H0N2; Q9Y266; Q9Y2B6"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; RND2 GTPase cycle"	"Ciliary landscape"	"8"	"0"	"628.1"	"841.7"	"2884.7"	"760.9"	"605.6"	"519.9"	"3793.4"	"463.6"	"614.2"	"459.9"	"508.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15067"	"Peroxisomal acyl-coenzyme A oxidase 1 OS=Homo sapiens OX=9606 GN=ACOX1 PE=1 SV=3"	"12"	"5"	"8"	"5"	"660"	"74.4"	"8.16"	"1082.21"	"18.83"	"3"	"4"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle"	"other molecular function"	"Pf01756, Pf02770, Pf14749"	"51"	"ENSG00000161533"	"ACOX1"	"A8K6X8; A8KAA0; B4DK61; F5GYQ8; hsa:51; Q12863; Q15067; Q15068; Q15101; Q16131; Q7Z3W5; Q9UD31"	"TYSND1 cleaves peroxisomal proteins"	"Estrogen receptor pathway; Nuclear receptors meta-pathway; PPAR signaling pathway; Eicosanoid metabolism via cyclooxygenases (COX); Eicosanoid metabolism via lipooxygenases (LOX); Omega-3 / omega-6 fatty acid synthesis"	"8"	"0"	"453.2"	"467.1"	"1922.8"	"461.5"	"324.1"	"326.8"	"1648.7"	"201.6"	"266.4"	"237.6"	"312.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P84098"	"60S ribosomal protein L19 OS=Homo sapiens OX=9606 GN=RPL19 PE=1 SV=1"	"21"	"6"	"12"	"5"	"196"	"23.5"	"11.47"	"2790.35"	"18.83"	"6"	"4"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01280"	"6143"	"ENSG00000108298"	"RPL19"	"B2R4K2; hsa:6143; P14118; P22908; P84098; Q502Y6; Q7Z6E4"	"Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"1"	"1025.0"	"1077.3"	"3043.1"	"938.0"	"908.1"	"781.2"	"3554.8"	"452.5"	"672.7"	"463.8"	"399.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P47985"	"Cytochrome b-c1 complex subunit Rieske, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRFS1 PE=1 SV=2"	"30"	"6"	"9"	"6"	"274"	"29.6"	"8.32"	"1055.28"	"18.82"	"3"	"6"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00355, Pf02921, Pf09165"	"7386"	"ENSG00000169021"	"UQCRFS1"	"A8K519; hsa:7386; P47985; Q6NVX5; Q9UPH2"	"Respiratory electron transport"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex III assembly; Iron metabolism disorders; Arsenic metabolism and reactive oxygen species generation"	"6"	"0"	"477.4"	"762.4"	"1727.9"	"675.2"	"782.3"	"696.8"	"2069.1"	"578.3"	"726.3"	"528.3"	"568.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q08945"	"FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1"	"10"	"6"	"11"	"6"	"709"	"81.0"	"6.87"	"2530.15"	"18.76"	"5"	"5"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00505, Pf03531, Pf08512, Pf17292"	"6749"	"ENSG00000149136"	"SSRP1"	"hsa:6749; Q08945; Q5BJG8"	"Regulation of TP53 Activity through Phosphorylation; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes"	""	"12"	"0"	"720.2"	"776.4"	"2846.1"	"637.0"	"509.3"	"479.6"	"1594.6"	"252.6"	"418.1"	"385.5"	"444.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19367"	"Hexokinase-1 OS=Homo sapiens OX=9606 GN=HK1 PE=1 SV=3"	"12"	"7"	"10"	"7"	"917"	"102.4"	"6.80"	"1848.59"	"18.67"	"5"	"5"	"other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;mitochondrion"	"kinase activity;other molecular function"	"Pf00349, Pf03727"	"3098"	"ENSG00000156515"	"HK1"	"E9PCK0; hsa:3098; O43443; O43444; O75574; P19367; Q5VTC3; Q96HC8; Q9NNZ4; Q9NNZ5"	"Glycolysis; Defective HK1 causes hexokinase deficiency (HK deficiency)"	"Cori cycle; Photodynamic therapy-induced HIF-1 survival signaling; Clear cell renal cell carcinoma pathways; Aerobic glycolysis; Disorders of fructose metabolism; Glucose metabolism in triple-negative breast cancer cells; Glycolysis and gluconeogenesis; UDP-derived sugars synthesis in fibroblasts; Glucuronidation"	"11"	"0"	"172.5"	"239.3"	"688.4"	"249.2"	"215.0"	"172.0"	"690.2"	"137.5"	"177.5"	"162.5"	"208.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WVM8"	"Sec1 family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCFD1 PE=1 SV=4"	"11"	"6"	"10"	"6"	"642"	"72.3"	"6.27"	"2284.85"	"18.67"	"5"	"5"	"stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi"	"other molecular function"	"Pf00995"	"23256"	"ENSG00000092108"	"SCFD1"	"A8K2Z5; B7Z4U7; B7Z594; hsa:23256; O60754; O94990; Q7Z529; Q8WVM8; Q9BZI3; Q9UNL3; Q9Y6A8"	"RHOA GTPase cycle; COPII-mediated vesicle transport"	""	"2"	"0"	"353.9"	"367.3"	"1062.0"	"414.5"	"390.2"	"334.7"	"1338.0"	"232.1"	"396.6"	"293.4"	"290.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P15121"	"Aldo-keto reductase family 1 member B1 OS=Homo sapiens OX=9606 GN=AKR1B1 PE=1 SV=3"	"27"	"6"	"10"	"5"	"316"	"35.8"	"6.98"	"1757.21"	"18.60"	"5"	"5"	"other metabolic processes;stress response;developmental processes;other biological processes"	"non-structural extracellular;cytosol;nucleus"	"other molecular function"	"Pf00248"	"231"	"ENSG00000085662"	"AKR1B1"	"B2R8N3; hsa:231; P15121; Q5U031; Q6FGA4; Q6ICP2; Q9BS21; Q9UCI9"	"Pregnenolone biosynthesis; Fructose biosynthesis"	"Eicosanoid metabolism via cyclooxygenases (COX); Disorders of galactose metabolism ; Polyol pathway; Metapathway biotransformation Phase I and II"	"6"	"1"	"249.7"	"268.2"	"1442.7"	"292.4"	"281.2"	"189.4"	"2034.8"	"164.6"	"329.9"	"295.3"	"285.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96I24"	"Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2"	"12"	"9"	"16"	"4"	"572"	"61.6"	"8.38"	"2739.34"	"18.58"	"9"	"6"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"translational apparatus;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00013"	"8939"	"ENSG00000107164"	"FUBP3"	"A3KFK8; A3KFL0; hsa:8939; Q92946; Q96I24; Q9BVB6"	""	""	"0"	"0"	"401.8"	"441.1"	"1742.1"	"378.8"	"339.0"	"248.2"	"1984.8"	"211.0"	"327.9"	"251.1"	"270.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49591"	"Serine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=SARS1 PE=1 SV=3"	"20"	"11"	"18"	"11"	"514"	"58.7"	"6.43"	"3808.48"	"18.54"	"10"	"7"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00587, Pf02403"	"6301"	"ENSG00000031698"	"SARS1"	"B2R6Y9; hsa:6301; P49591; Q5T5C8; Q9NSE3"	"Cytosolic tRNA aminoacylation; Selenocysteine synthesis"	"VEGFA-VEGFR2 signaling"	"3"	"0"	"682.8"	"843.8"	"3007.5"	"751.3"	"677.2"	"520.7"	"3466.1"	"422.0"	"616.1"	"488.1"	"505.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35249"	"Replication factor C subunit 4 OS=Homo sapiens OX=9606 GN=RFC4 PE=1 SV=2"	"22"	"6"	"11"	"6"	"363"	"39.7"	"8.02"	"2369.63"	"18.53"	"6"	"5"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00004, Pf08542"	"5984"	"ENSG00000163918"	"RFC4"	"B4DM41; D3DNV2; hsa:5984; P35249; Q6FHX7"	"Activation of ATR in response to replication stress; Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Polymerase switching on the C-strand of the telomere; Polymerase switching; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER"	"Gastric cancer network 2; Retinoblastoma gene in cancer; DNA replication; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"28"	"0"	"331.7"	"361.0"	"1260.9"	"361.6"	"332.0"	"262.4"	"1295.9"	"154.8"	"226.3"	"195.5"	"183.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NYU2"	"UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3"	"6"	"5"	"6"	"5"	"1555"	"177.1"	"5.63"	"634.78"	"18.44"	"2"	"4"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"ER/Golgi;other cell component"	"other molecular function"	"Pf06427, Pf18400, Pf18401, Pf18402, Pf18403, Pf18404"	"56886"	"ENSG00000136731"	"UGGT1"	"hsa:56886; Q53QP2; Q53SL3; Q8IW30; Q9H8I4; Q9NYU2"	"ER Quality Control Compartment (ERQC)"	"IL-18 signaling pathway"	"2"	"0"	"72.0"	"98.6"	"231.8"	"103.0"	"101.1"	"97.5"	"265.6"	"72.5"	"105.0"	"83.3"	"78.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51858"	"Hepatoma-derived growth factor OS=Homo sapiens OX=9606 GN=HDGF PE=1 SV=1"	"32"	"7"	"12"	"7"	"240"	"26.8"	"4.73"	"2462.11"	"18.44"	"7"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;signal transduction;other biological processes"	"nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00855"	"3068"	"ENSG00000143321"	"HDGF"	"B3KU21; D3DVC9; hsa:3068; P51858; Q5SZ07; Q5SZ08; Q5SZ09"	"XBP1(S) activates chaperone genes"	"IL-18 signaling pathway"	"2"	"0"	"438.4"	"464.2"	"2081.4"	"464.1"	"425.5"	"237.9"	"2558.3"	"255.5"	"366.6"	"205.7"	"176.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55809"	"Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial OS=Homo sapiens OX=9606 GN=OXCT1 PE=1 SV=1"	"11"	"4"	"7"	"4"	"520"	"56.1"	"7.46"	"682.74"	"18.43"	"2"	"4"	"other metabolic processes;stress response;developmental processes;other biological processes"	"mitochondrion"	"other molecular function"	"Pf01144"	"5019"	"ENSG00000083720"	"OXCT1"	"B2R5V2; B7Z528; hsa:5019; P55809"	"Utilization of Ketone Bodies"	""	"1"	"0"	"124.1"	"140.0"	"523.5"	"130.0"	"145.2"	"89.5"	"628.4"	"85.2"	"139.0"	"95.5"	"105.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82979"	"SAP domain-containing ribonucleoprotein OS=Homo sapiens OX=9606 GN=SARNP PE=1 SV=3"	"23"	"5"	"12"	"5"	"210"	"23.7"	"6.42"	"2078.68"	"18.42"	"4"	"4"	"other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02037"	"84324"	"ENSG00000205323"	"SARNP"	"A8K393; hsa:84324; P82979; Q9P066"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	""	"3"	"0"	"481.6"	"575.2"	"1535.1"	"503.8"	"639.4"	"520.1"	"2993.0"	"710.5"	"1363.9"	"1025.6"	"1154.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46783"	"40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1"	"47"	"8"	"22"	"7"	"165"	"18.9"	"10.15"	"5609.86"	"18.40"	"8"	"4"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf03501"	"6204"	"ENSG00000124614"	"RPS10"	"B2R4E3; hsa:6204; P46783; Q5TZC0"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"2"	"2209.3"	"2468.5"	"6115.8"	"1960.1"	"1889.0"	"1677.7"	"6472.6"	"900.1"	"1246.4"	"904.8"	"925.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43447"	"Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1"	"32"	"6"	"12"	"6"	"177"	"19.2"	"8.07"	"2453.73"	"18.34"	"5"	"5"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00160"	"10465"	"ENSG00000171960"	"PPIH"	"A6NNE7; hsa:10465; O43447"	"mRNA Splicing - Major Pathway; SARS-CoV-1 activates/modulates innate immune responses"	""	"2"	"0"	"635.1"	"801.7"	"2452.7"	"897.6"	"809.5"	"757.6"	"3069.5"	"638.8"	"1148.1"	"1077.0"	"1337.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y285"	"Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3"	"13"	"6"	"11"	"6"	"508"	"57.5"	"7.80"	"2053.72"	"18.25"	"5"	"5"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01409, Pf18552, Pf18553, Pf18554"	"2193"	"ENSG00000179115"	"FARSA"	"B4E363; hsa:2193; Q9NSD8; Q9Y285; Q9Y4W8"	"Cytosolic tRNA aminoacylation"	""	"1"	"0"	"665.1"	"716.0"	"1791.6"	"671.3"	"629.5"	"584.9"	"1592.2"	"282.4"	"360.4"	"291.6"	"274.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06493"	"Cyclin-dependent kinase 1 OS=Homo sapiens OX=9606 GN=CDK1 PE=1 SV=3"	"20"	"4"	"8"	"4"	"297"	"34.1"	"8.40"	"2109.02"	"18.24"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069"	"983"	"ENSG00000170312"	"CDK1"	"A8K7C4; C9J497; hsa:983; O60764; P06493"	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A; MAPK6/MAPK4 signaling; The role of GTSE1 in G2/M progression after G2 checkpoint; Golgi Cisternae Pericentriolar Stack Reorganization; Resolution of Sister Chromatid Cohesion; Recruitment of NuMA to mitotic centrosomes; Nuclear Pore Complex (NPC) Disassembly; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Regulation of TP53 Degradation; APC/C:Cdc20 mediated degradation of Cyclin B; Phosphorylation of the APC/C; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Transcriptional regulation by RUNX2; Ovarian tumor domain proteases; MASTL Facilitates Mitotic Progression; E2F-enabled inhibition of pre-replication complex formation; MAPK3 (ERK1) activation; Condensation of Prophase Chromosomes; G1/S-Specific Transcription; Initiation of Nuclear Envelope (NE) Reformation; Condensation of Prometaphase Chromosomes; Activation of NIMA Kinases NEK9, NEK6, NEK7; G2/M DNA replication checkpoint; Depolymerization of the Nuclear Lamina; Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1; Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes; Phosphorylation of Emi1"	"miRNA regulation of DNA damage response; Cell cycle; Microtubule cytoskeleton regulation; Spinal cord injury; Retinoblastoma gene in cancer; ATM signaling pathway; PPAR-alpha pathway; Nuclear receptors meta-pathway; ATM signaling in development and disease ; G1 to S cell cycle control; Cohesin complex - Cornelia de Lange syndrome; Urotensin-II-mediated signaling pathway; DNA damage response"	"49"	"0"	"193.1"	"229.4"	"830.8"	"207.4"	"209.0"	"153.8"	"1063.8"	"136.0"	"211.4"	"217.2"	"289.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49959"	"Double-strand break repair protein MRE11 OS=Homo sapiens OX=9606 GN=MRE11 PE=1 SV=3"	"6"	"3"	"8"	"3"	"708"	"80.5"	"5.90"	"1892.75"	"18.21"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00149, Pf04152"	"4361"	"ENSG00000020922"	"MRE11"	"B3KTC7; hsa:4361; O43475; P49959"	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; Meiotic recombination; DNA Damage/Telomere Stress Induced Senescence; Nonhomologous End-Joining (NHEJ); Resolution of D-loop Structures through Holliday Junction Intermediates; Regulation of TP53 Activity through Phosphorylation; Presynaptic phase of homologous DNA pairing and strand exchange; Cytosolic sensors of pathogen-associated DNA ; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; HDR through MMEJ (alt-NHEJ); Sensing of DNA Double Strand Breaks; IRF3-mediated induction of type I IFN"	"miRNA regulation of DNA damage response; Homologous recombination; DDX1 as a regulatory component of the Drosha microprocessor; ATM signaling in development and disease ; Breast cancer pathway; Joubert syndrome; DNA repair pathways, full network; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; Neurogenesis regulation in the olfactory epithelium; DNA damage response"	"32"	"0"	"83.9"	"115.7"	"421.7"	"100.0"	"98.4"	"73.9"	"377.5"	"50.4"	"75.8"	"63.0"	"54.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P20618"	"Proteasome subunit beta type-1 OS=Homo sapiens OX=9606 GN=PSMB1 PE=1 SV=2"	"23"	"3"	"7"	"3"	"241"	"26.5"	"8.13"	"1146.68"	"18.20"	"2"	"3"	"protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	""	"Pf00227"	"5689"	"ENSG00000008018"	"PSMB1"	"B5BU76; hsa:5689; P20618; Q9BWA8"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Neutrophil degranulation"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"63"	"0"	"287.1"	"322.5"	"930.1"	"291.6"	"261.9"	"206.1"	"834.6"	"185.4"	"248.3"	"178.1"	"210.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P18077"	"60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A PE=1 SV=2"	"47"	"7"	"15"	"7"	"110"	"12.5"	"11.06"	"2926.02"	"18.12"	"7"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01247"	"6165"	"ENSG00000182899"	"RPL35A"	"hsa:6165; P18077; Q08ES9; Q9BVN7"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"1761.2"	"1951.8"	"5981.0"	"1659.7"	"1526.3"	"1349.6"	"4821.0"	"470.0"	"638.8"	"531.4"	"501.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15144"	"Actin-related protein 2/3 complex subunit 2 OS=Homo sapiens OX=9606 GN=ARPC2 PE=1 SV=1"	"15"	"6"	"11"	"6"	"300"	"34.3"	"7.36"	"1714.53"	"18.12"	"5"	"6"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity"	"Pf04045"	"10109"	"ENSG00000163466"	"ARPC2"	"hsa:10109; O15144; Q92801; Q9P1D4"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Clathrin-mediated endocytosis; EPHB-mediated forward signaling"	"Pathogenic Escherichia coli infection"	"6"	"0"	"419.9"	"395.3"	"1417.9"	"369.9"	"281.4"	"239.8"	"1275.3"	"273.4"	"580.3"	"1016.7"	"1639.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25788"	"Proteasome subunit alpha type-3 OS=Homo sapiens OX=9606 GN=PSMA3 PE=1 SV=2"	"19"	"5"	"12"	"5"	"255"	"28.4"	"5.33"	"2011.77"	"18.07"	"5"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00227, Pf10584"	"5684"	"ENSG00000100567"	"PSMA3"	"B2RCK6; hsa:5684; P25788; Q86U83; Q8N1D8; Q9BS70"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Cross-presentation of soluble exogenous antigens (endosomes); Regulation of ornithine decarboxylase (ODC); Somitogenesis"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"62"	"0"	"398.9"	"397.4"	"1471.6"	"401.3"	"301.1"	"242.5"	"1410.8"	"347.8"	"402.1"	"377.2"	"390.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46459"	"Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3"	"10"	"6"	"12"	"6"	"744"	"82.5"	"6.95"	"1993.24"	"18.02"	"6"	"6"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00004, Pf02359, Pf02933, Pf17862"	"4905"	"ENSG00000073969; ENSG00000276262; ENSG00000278174"	"NSF"	"A8K2D9; B4DFA2; hsa:4905; P46459; Q8N6D7; Q9UKZ2"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport; Intra-Golgi traffic; COPII-mediated vesicle transport; Retrograde transport at the Trans-Golgi-Network; Trafficking of GluR2-containing AMPA receptors"	"Synaptic vesicle pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway"	"8"	"0"	"302.2"	"290.9"	"1478.9"	"237.7"	"178.2"	"134.6"	"1417.8"	"95.7"	"133.7"	"127.9"	"108.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62266"	"40S ribosomal protein S23 OS=Homo sapiens OX=9606 GN=RPS23 PE=1 SV=3"	"33"	"4"	"10"	"4"	"143"	"15.8"	"10.49"	"1723.77"	"17.94"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00164"	"6228"	"ENSG00000186468"	"RPS23"	"hsa:6228; P39028; P62266; Q6IB08"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"734.3"	"748.8"	"2286.5"	"682.4"	"740.7"	"541.4"	"2563.5"	"385.0"	"417.2"	"343.3"	"407.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49207"	"60S ribosomal protein L34 OS=Homo sapiens OX=9606 GN=RPL34 PE=1 SV=3"	"29"	"5"	"13"	"5"	"117"	"13.3"	"11.47"	"2545.57"	"17.94"	"5"	"4"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01199"	"6164"	"ENSG00000109475"	"RPL34"	"hsa:6164; P49207; Q6FG66; Q9BUZ2"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"1150.0"	"1269.0"	"3195.6"	"932.4"	"843.2"	"779.1"	"3565.7"	"405.7"	"586.8"	"404.9"	"410.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBS4"	"DnaJ homolog subfamily B member 11 OS=Homo sapiens OX=9606 GN=DNAJB11 PE=1 SV=1"	"18"	"5"	"10"	"5"	"358"	"40.5"	"6.18"	"2213.90"	"17.92"	"4"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"non-structural extracellular;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00226, Pf01556"	"51726"	"ENSG00000090520"	"DNAJB11"	"hsa:51726; Q542Y5; Q542Y9; Q6IAQ8; Q96JC6; Q9UBS4"	"XBP1(S) activates chaperone genes"	"Photodynamic therapy-induced unfolded protein response"	"2"	"0"	"475.6"	"780.9"	"1900.4"	"978.0"	"874.2"	"758.0"	"1530.6"	"284.8"	"488.9"	"370.5"	"349.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14602"	"Eukaryotic translation initiation factor 1A, Y-chromosomal OS=Homo sapiens OX=9606 GN=EIF1AY PE=1 SV=4"	"38"	"5"	"9"	"5"	"144"	"16.4"	"5.24"	"2146.54"	"17.85"	"5"	"4"	"protein metabolism;other metabolic processes"	"other cell component"	"nucleic acid binding activity"	"Pf01176"	"9086"	"ENSG00000198692"	"EIF1AY"	"hsa:9086; O14602; Q9BS77"	""	"Translation factors"	"1"	"0"	"469.1"	"491.8"	"1195.7"	"523.8"	"496.9"	"397.0"	"1865.1"	"388.0"	"535.0"	"423.3"	"429.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96CX2"	"BTB/POZ domain-containing protein KCTD12 OS=Homo sapiens OX=9606 GN=KCTD12 PE=1 SV=1"	"19"	"5"	"10"	"5"	"325"	"35.7"	"5.64"	"1862.50"	"17.79"	"5"	"5"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf02214"	"115207"	"ENSG00000178695"	"KCTD12"	"hsa:115207; Q96CX2"	""	""	"0"	"0"	"149.6"	"179.1"	"666.1"	"175.1"	"161.5"	"141.9"	"808.7"	"95.5"	"130.2"	"113.2"	"162.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75534"	"Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2"	"9"	"7"	"12"	"7"	"798"	"88.8"	"6.25"	"1950.53"	"17.78"	"6"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"nucleic acid binding activity"	"Pf00313, Pf12901"	"7812"	"ENSG00000009307"	"CSDE1"	"A8K281; E9PGZ0; G5E9Q2; hsa:7812; O75534; O94961; Q5TF04; Q5TF05; Q68DF1; Q68DI9; Q9Y2S4"	""	""	"0"	"0"	"459.2"	"538.7"	"2137.1"	"523.0"	"492.6"	"380.2"	"2454.9"	"275.7"	"377.2"	"295.5"	"292.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P38606"	"V-type proton ATPase catalytic subunit A OS=Homo sapiens OX=9606 GN=ATP6V1A PE=1 SV=2"	"11"	"5"	"10"	"5"	"617"	"68.3"	"5.52"	"2086.61"	"17.72"	"5"	"5"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf00006, Pf02874, Pf16886"	"523"	"ENSG00000114573"	"ATP6V1A"	"B2RBR8; B7Z1R5; D3DN75; hsa:523; P38606; Q53YD9; Q96DY6; Q9UHY3"	"Amino acids regulate mTORC1; ROS and RNS production in phagocytes; Insulin receptor recycling; Transferrin endocytosis and recycling; Ion channel transport"	"Proximal tubule transport"	"6"	"0"	"85.1"	"91.5"	"290.0"	"86.5"	"90.4"	"64.4"	"319.2"	"55.5"	"72.7"	"57.4"	"57.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62888"	"60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2"	"55"	"8"	"17"	"7"	"115"	"12.8"	"9.63"	"4515.54"	"17.70"	"8"	"5"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01248"	"6156"	"ENSG00000156482"	"RPL30"	"B2R591; hsa:6156; P04645; P62888; Q502Z6"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"756.9"	"714.6"	"2026.4"	"672.1"	"582.4"	"489.7"	"2938.2"	"277.6"	"478.1"	"307.7"	"296.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92917"	"G-patch domain and KOW motifs-containing protein OS=Homo sapiens OX=9606 GN=GPKOW PE=1 SV=2"	"14"	"4"	"9"	"4"	"476"	"52.2"	"6.15"	"1429.60"	"17.69"	"3"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00467, Pf12656"	"27238"	"ENSG00000068394"	"GPKOW"	"hsa:27238; Q59EK5; Q92917; Q9BQA8"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"172.8"	"145.5"	"352.3"	"145.4"	"165.1"	"129.3"	"395.2"	"84.4"	"160.5"	"174.3"	"252.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05198"	"Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3"	"17"	"6"	"12"	"5"	"315"	"36.1"	"5.08"	"1794.45"	"17.46"	"6"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf00575, Pf07541"	"1965"	"ENSG00000134001"	"EIF2S1"	"hsa:1965; P05198"	"ABC-family proteins mediated transport; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK1 (HRI) to heme deficiency; PERK regulates gene expression; Recycling of eIF2:GDP; Response of EIF2AK4 (GCN2) to amino acid deficiency"	"Translation factors; Alzheimer's disease and miRNA effects; Brain-derived neurotrophic factor (BDNF) signaling pathway; Ebola virus infection in host; Nonalcoholic fatty liver disease; Measles virus infection; Unfolded protein response; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell; Alzheimer's disease"	"19"	"0"	"648.4"	"714.2"	"2240.3"	"612.2"	"536.1"	"501.1"	"1512.5"	"245.6"	"443.3"	"569.4"	"1098.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H9B4"	"Sideroflexin-1 OS=Homo sapiens OX=9606 GN=SFXN1 PE=1 SV=4"	"23"	"7"	"13"	"7"	"322"	"35.6"	"9.07"	"2180.35"	"17.43"	"7"	"6"	"other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity"	"Pf03820"	"94081"	"ENSG00000164466"	"SFXN1"	"B3KPW3; D3DQN2; hsa:94081; Q9H9B4; Q9HA53"	""	""	"0"	"0"	"518.9"	"524.2"	"1909.5"	"465.6"	"423.4"	"332.2"	"1936.1"	"268.0"	"336.6"	"310.2"	"330.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01518"	"Adenylyl cyclase-associated protein 1 OS=Homo sapiens OX=9606 GN=CAP1 PE=1 SV=5"	"16"	"7"	"10"	"7"	"475"	"51.9"	"8.06"	"1686.87"	"17.40"	"5"	"5"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01213, Pf08603"	"10487"	"ENSG00000131236"	"CAP1"	"hsa:10487; Q01518; Q53HR7; Q5T0S1; Q5T0S2; Q6I9U6"	"Neutrophil degranulation; Platelet degranulation ; Role of ABL in ROBO-SLIT signaling"	"Angiopoietin-like protein 8 regulatory pathway; Insulin signaling; Complement system in neuronal development and plasticity; Opioid receptor pathways"	"7"	"0"	"588.7"	"599.0"	"2294.2"	"513.2"	"412.4"	"282.9"	"2375.8"	"237.3"	"327.4"	"272.2"	"252.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14923"	"Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3"	"12"	"9"	"16"	"7"	"745"	"81.7"	"6.14"	"2807.00"	"17.38"	"9"	"7"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;RNA metabolism OR transcription;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00514"	"3728"	"ENSG00000173801"	"JUP"	"hsa:3728; P14923; Q15093; Q15151; Q7L3S5; Q86W21; Q9BWC4; Q9HCX9"	"Neutrophil degranulation; RHOC GTPase cycle; Formation of the cornified envelope; RHOA GTPase cycle; CDC42 GTPase cycle; RHOQ GTPase cycle; RHOB GTPase cycle; RHOJ GTPase cycle; VEGFR2 mediated vascular permeability; Adherens junctions interactions; Regulation of CDH11 function; Regulation of CDH19 Expression and Function; CDH11 homotypic and heterotypic interactions; RHOH GTPase cycle"	"Arrhythmogenic right ventricular cardiomyopathy; Corticotropin-releasing hormone signaling pathway; Ectoderm differentiation; Ectoderm differentiation; Epithelial to mesenchymal transition in colorectal cancer; Opioid receptor pathways"	"21"	"2"	"2544.7"	"1076.8"	"1140.5"	"739.1"	"352.8"	"261.3"	"1081.6"	"422.6"	"283.6"	"262.6"	"395.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P20042"	"Eukaryotic translation initiation factor 2 subunit 2 OS=Homo sapiens OX=9606 GN=EIF2S2 PE=1 SV=2"	"15"	"5"	"11"	"5"	"333"	"38.4"	"5.80"	"2377.57"	"17.37"	"5"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01873"	"8894"	"ENSG00000125977"	"EIF2S2"	"hsa:8894; P20042; Q9BVU0; Q9UJE4"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; ABC-family proteins mediated transport; Response of EIF2AK1 (HRI) to heme deficiency; PERK regulates gene expression; Recycling of eIF2:GDP; Response of EIF2AK4 (GCN2) to amino acid deficiency"	"Translation factors; Brain-derived neurotrophic factor (BDNF) signaling pathway; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell; Primary ovarian insufficiency"	"14"	"0"	"588.9"	"611.0"	"1917.7"	"584.7"	"533.5"	"484.2"	"1208.7"	"233.0"	"481.1"	"779.1"	"1389.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NR31"	"GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1"	"34"	"5"	"10"	"3"	"198"	"22.4"	"6.68"	"1859.75"	"17.32"	"4"	"4"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf00025"	"56681"	"ENSG00000079332"	"SAR1A"	"B4DQ19; hsa:56681; Q9NR31"	""	"Sterol regulatory element-binding proteins (SREBP) signaling"	"1"	"2"	"187.2"	"290.5"	"871.1"	"277.5"	"343.4"	"347.3"	"1186.8"	"211.9"	"394.7"	"248.3"	"221.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7L576"	"Cytoplasmic FMR1-interacting protein 1 OS=Homo sapiens OX=9606 GN=CYFIP1 PE=1 SV=1"	"6"	"6"	"12"	"6"	"1253"	"145.1"	"6.90"	"2034.38"	"17.30"	"6"	"6"	"cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf05994, Pf07159"	"23191"	"ENSG00000273749; ENSG00000288461"	"CYFIP1"	"A8K6D9; hsa:23191; Q14467; Q5IED0; Q6ZSX1; Q7L576; Q9BSD9; Q9BVC7"	"Neutrophil degranulation; VEGFA-VEGFR2 Pathway; RAC3 GTPase cycle; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RAC1 GTPase cycle; RHOG GTPase cycle; RHO GTPases Activate WASPs and WAVEs; RAC2 GTPase cycle"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; Prader-Willi and Angelman syndrome; Fragile X syndrome; Disruption of postsynaptic signaling by CNV; 15q11.2 copy number variation syndrome; G13 signaling pathway"	"15"	"0"	"348.2"	"326.2"	"908.2"	"328.0"	"297.2"	"257.8"	"463.6"	"95.6"	"169.5"	"167.7"	"162.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UN86"	"Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2"	"15"	"6"	"10"	"4"	"482"	"54.1"	"5.55"	"1777.09"	"17.25"	"5"	"5"	"cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf02136"	"9908"	"ENSG00000138757"	"G3BP2"	"A8K6X1; hsa:9908; O60606; O75149; Q9UN86; Q9UPA1"	"SARS-CoV-2 activates/modulates innate and adaptive immune responses"	""	"1"	"0"	"325.8"	"409.2"	"1314.7"	"446.4"	"421.6"	"360.8"	"1695.3"	"221.0"	"362.5"	"267.8"	"271.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50454"	"Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2"	"14"	"4"	"7"	"4"	"418"	"46.4"	"8.69"	"1284.77"	"17.22"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"non-structural extracellular;other membranes;ER/Golgi"	"enzyme regulator activity;other molecular function"	"Pf00079"	"871"	"ENSG00000149257"	"SERPINH1"	"B3KVJ3; hsa:871; P29043; P50454; Q5XPB4; Q6NSJ6; Q8IY96; Q9NP88"	"Collagen biosynthesis and modifying enzymes"	"Endochondral ossification; Type I collagen synthesis in the context of osteogenesis imperfecta; Endochondral ossification with skeletal dysplasias; 15q13.3 copy number variation syndrome"	"5"	"0"	"217.1"	"207.5"	"823.6"	"219.1"	"192.4"	"135.2"	"917.3"	"142.5"	"167.8"	"135.2"	"143.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43719"	"HIV Tat-specific factor 1 OS=Homo sapiens OX=9606 GN=HTATSF1 PE=1 SV=1"	"9"	"6"	"10"	"6"	"755"	"85.8"	"4.40"	"2415.22"	"17.21"	"6"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	"Pf00076"	"27336"	"ENSG00000102241"	"HTATSF1"	"D3DWG9; hsa:27336; O43719; Q59G06; Q99730"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"517.2"	"570.7"	"1688.6"	"593.1"	"544.5"	"508.8"	"1806.2"	"342.8"	"506.5"	"428.0"	"380.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96DI7"	"U5 small nuclear ribonucleoprotein 40 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP40 PE=1 SV=1"	"10"	"3"	"8"	"3"	"357"	"39.3"	"8.10"	"1816.89"	"17.20"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf00400"	"9410"	"ENSG00000060688"	"SNRNP40"	"B4DQJ1; hsa:9410; O75938; O95320; Q96DI7"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"mRNA processing"	"3"	"0"	"237.8"	"253.7"	"839.7"	"260.3"	"253.3"	"203.8"	"1014.8"	"163.2"	"494.3"	"494.2"	"714.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P01116"	"GTPase KRas OS=Homo sapiens OX=9606 GN=KRAS PE=1 SV=1"	"28"	"3"	"7"	"3"	"189"	"21.6"	"6.77"	"967.45"	"17.17"	"2"	"3"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00071"	"3845"	"ENSG00000133703"	"KRAS"	"A8K8Z5; B0LPF9; hsa:3845; P01116; P01118; Q96D10"	"Signaling by CSF3 (G-CSF); Signaling by CSF1 (M-CSF) in myeloid cells; RAS processing; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAS GAP mutants; Signaling by RAS GTPase mutants; RUNX3 regulates p14-ARF"	"IL-5 signaling pathway; Alzheimer's disease and miRNA effects; Glioblastoma signaling pathways; RalA downstream regulated genes; TNF-alpha signaling pathway; Oncostatin M signaling pathway; Aryl hydrocarbon receptor pathway; Bladder cancer; Extracellular vesicle-mediated signaling in recipient cells; RAC1/PAK1/p38/MMP2 pathway; G protein signaling pathways; BDNF-TrkB signaling; MAPK signaling pathway; PI3K-AKT-mTOR signaling pathway and therapeutic opportunities; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Endometrial cancer; PI3K-Akt signaling pathway; Chromosomal and microsatellite instability in colorectal cancer ; MAPK cascade; Ras signaling; Epithelial to mesenchymal transition in colorectal cancer; Non-small cell lung cancer; Breast cancer pathway; Pancreatic adenocarcinoma pathway; Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells; Thermogenesis; Non-genomic actions of 1,25 dihydroxyvitamin D3; EGF/EGFR signaling pathway; Relationship between inflammation, COX-2 and EGFR; Envelope proteins and their potential roles in EDMD physiopathology; Synaptic signaling pathways associated with autism spectrum disorder; Hippo-Merlin signaling dysregulation; Fragile X syndrome; Gastrin signaling pathway; Hepatitis B infection; Head and neck squamous cell carcinoma; Melanoma; EGFR tyrosine kinase inhibitor resistance; Kisspeptin/kisspeptin receptor system in the ovary; MAPK pathway in congenital thyroid cancer; Regulation of actin cytoskeleton; Alzheimer's disease; Autophagy in pancreatic ductal adenocarcinoma; JAK-STAT signaling in the regulation of Beta-cells; ErbB signaling pathway; DNA damage response (only ATM dependent); Serotonin receptor 2 and ELK-SRF/GATA4 signaling"	"57"	"0"	"56.3"	"59.7"	"170.3"	"60.8"	"70.8"	"52.9"	"246.1"	"61.8"	"139.3"	"121.8"	"175.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55036"	"26S proteasome non-ATPase regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMD4 PE=1 SV=1"	"19"	"6"	"10"	"6"	"377"	"40.7"	"4.79"	"1999.79"	"17.10"	"5"	"5"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf02809, Pf13519"	"5710"	"ENSG00000159352"	"PSMD4"	"D3DV16; hsa:5710; P55036; Q5VWC5; Q9NS92"	"MAPK6/MAPK4 signaling; Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; UCH proteinases; Regulation of expression of SLITs and ROBOs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; VEGFA-VEGFR2 signaling; Alzheimer's disease"	"64"	"0"	"493.9"	"587.7"	"1818.3"	"555.2"	"449.9"	"382.6"	"1549.1"	"210.3"	"340.0"	"368.9"	"562.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35606"	"Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2"	"6"	"4"	"9"	"4"	"906"	"102.4"	"5.27"	"2148.77"	"17.10"	"3"	"4"	"transport"	"other membranes;cytosol;ER/Golgi"	"other molecular function"	"Pf00400, Pf04053"	"9276"	"ENSG00000184432"	"COPB2"	"B4DZI8; hsa:9276; P35606"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport"	""	"2"	"0"	"325.6"	"345.9"	"1132.0"	"296.0"	"254.6"	"234.6"	"977.2"	"114.7"	"188.2"	"136.2"	"139.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NR45"	"Sialic acid synthase OS=Homo sapiens OX=9606 GN=NANS PE=1 SV=2"	"14"	"5"	"9"	"5"	"359"	"40.3"	"6.74"	"1671.53"	"16.96"	"4"	"5"	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf03102"	"54187"	"ENSG00000095380"	"NANS"	"B2RE98; hsa:54187; Q8WUV9; Q9BWS6; Q9NR45; Q9NVD4"	"Sialic acid metabolism"	""	"1"	"0"	"205.9"	"232.9"	"982.2"	"223.6"	"204.2"	"142.9"	"1264.2"	"137.9"	"249.8"	"153.6"	"122.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31150"	"Rab GDP dissociation inhibitor alpha OS=Homo sapiens OX=9606 GN=GDI1 PE=1 SV=2"	"19"	"7"	"11"	"2"	"447"	"50.6"	"5.14"	"2892.68"	"16.91"	"6"	"5"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00996"	"2664"	"ENSG00000203879"	"GDI1"	"hsa:2664; P31150; P50394; Q6FG50; Q7Z2G6; Q7Z2G9; Q7Z2H5; Q7Z2I6"	"RAB GEFs exchange GTP for GDP on RABs"	"Ciliary landscape; Airway smooth muscle cell contraction; 10q11.21q11.23 copy number variation syndrome"	"4"	"0"	"87.5"	"106.1"	"452.7"	"104.1"	"104.1"	"64.0"	"497.3"	"55.3"	"98.0"	"80.1"	"58.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14166"	"Tubulin--tyrosine ligase-like protein 12 OS=Homo sapiens OX=9606 GN=TTLL12 PE=1 SV=2"	"10"	"5"	"9"	"5"	"644"	"74.4"	"5.53"	"1256.46"	"16.86"	"4"	"5"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03133"	"23170"	"ENSG00000100304"	"TTLL12"	"hsa:23170; Q14166; Q20WK5; Q9UGU3"	"Carboxyterminal post-translational modifications of tubulin"	""	"1"	"0"	"155.2"	"230.4"	"787.1"	"233.6"	"204.5"	"201.2"	"935.5"	"191.9"	"357.0"	"260.2"	"268.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16658"	"Fascin OS=Homo sapiens OX=9606 GN=FSCN1 PE=1 SV=3"	"10"	"4"	"9"	"4"	"493"	"54.5"	"7.24"	"2087.82"	"16.83"	"4"	"3"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf06268"	"6624"	"ENSG00000075618"	"FSCN1"	"A6NI89; B2RE97; hsa:6624; Q16658; Q96IC5; Q96IH1; Q9BRF1"	"Interleukin-4 and Interleukin-13 signaling"	"VEGFA-VEGFR2 signaling; Urotensin-II-mediated signaling pathway"	"3"	"0"	"142.2"	"184.3"	"849.3"	"167.7"	"142.6"	"93.9"	"1327.4"	"143.1"	"152.4"	"109.4"	"111.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23527"	"Histone H2B type 1-O OS=Homo sapiens OX=9606 GN=H2BC17 PE=1 SV=3"	"42"	"5"	"11"	"1"	"126"	"13.9"	"10.32"	"2099.44"	"16.83"	"5"	"4"	"cell organization and biogenesis"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125"	"8348"	"ENSG00000274641"	"H2BC17"	"hsa:8348; P23527; Q3KPI7; Q8TCV6"	"B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Promoter Escape; E3 ubiquitin ligases ubiquitinate target proteins; Amyloid fiber formation; Meiotic synapsis; HCMV Late Events; Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; HCMV Early Events; Transcriptional regulation by small RNAs; Deposition of new CENPA-containing nucleosomes at the centromere; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Formation of the beta-catenin:TCF transactivating complex; Oxidative Stress Induced Senescence; HDACs deacetylate histones; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Pre-NOTCH Transcription and Translation; Senescence-Associated Secretory Phenotype (SASP); RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; HATs acetylate histones; Meiotic recombination; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Packaging Of Telomere Ends; Condensation of Prophase Chromosomes; DNA Damage/Telomere Stress Induced Senescence; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; Nonhomologous End-Joining (NHEJ); RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis"	""	"43"	"5"	"408.4"	"469.0"	"1264.8"	"360.6"	"371.0"	"304.4"	"1282.6"	"237.6"	"303.9"	"231.6"	"246.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q02218"	"2-oxoglutarate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=OGDH PE=1 SV=3"	"8"	"6"	"10"	"6"	"1023"	"115.9"	"6.86"	"1731.03"	"16.79"	"5"	"5"	"protein metabolism;other metabolic processes;developmental processes"	"other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00676, Pf02779, Pf16078, Pf16870"	"4967"	"ENSG00000105953"	"OGDH"	"B4E2U9; D3DVL0; E9PBM1; hsa:4967; Q02218; Q96DD3; Q9UDX0"	"Lysine catabolism; Glyoxylate metabolism and glycine degradation; Citric acid cycle (TCA cycle)"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Thiamine metabolic pathways; 7q11.23 copy number variation syndrome; TCA cycle (aka Krebs or citric acid cycle)"	"8"	"0"	"139.7"	"170.5"	"457.0"	"176.1"	"165.8"	"130.4"	"461.7"	"74.7"	"136.1"	"83.7"	"84.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P54727"	"UV excision repair protein RAD23 homolog B OS=Homo sapiens OX=9606 GN=RAD23B PE=1 SV=1"	"15"	"6"	"10"	"4"	"409"	"43.1"	"4.84"	"2365.22"	"16.78"	"6"	"4"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00240, Pf00627, Pf09280"	"5887"	"ENSG00000119318"	"RAD23B"	"B3KWK8; G5E9P0; hsa:5887; P54727; Q7Z5K8; Q8WUB0"	"Josephin domain DUBs; Formation of Incision Complex in GG-NER; DNA Damage Recognition in GG-NER; N-glycan trimming in the ER and Calnexin/Calreticulin cycle"	"Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"7"	"1"	"401.8"	"512.8"	"1584.0"	"550.7"	"586.3"	"570.5"	"1796.3"	"311.8"	"486.6"	"357.8"	"334.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5JSL3"	"Dedicator of cytokinesis protein 11 OS=Homo sapiens OX=9606 GN=DOCK11 PE=1 SV=2"	"2"	"4"	"10"	"4"	"2073"	"237.5"	"7.74"	"1855.76"	"16.75"	"4"	"4"	"signal transduction;other biological processes"	"cytosol"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf06920, Pf11878, Pf14429, Pf20421, Pf20422"	"139818"	"ENSG00000147251"	"DOCK11"	"A6NMF0; hsa:139818; Q5JSL3; Q66M66; Q6ZUJ5; Q86VU8; Q96MN3"	"Factors involved in megakaryocyte development and platelet production; CDC42 GTPase cycle; RAC1 GTPase cycle"	""	"3"	"0"	"150.0"	"144.8"	"448.1"	"153.2"	"140.9"	"120.4"	"473.8"	"120.5"	"341.0"	"367.8"	"355.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H3P2"	"Negative elongation factor A OS=Homo sapiens OX=9606 GN=NELFA PE=1 SV=3"	"8"	"3"	"10"	"3"	"528"	"57.2"	"9.03"	"1885.91"	"16.73"	"2"	"3"	"other biological processes"	"cytosol;nucleus"	"other molecular function"	""	"7469"	"ENSG00000185049"	"NELFA"	"A2A2T1; hsa:7469; O95392; Q9H3P2"	"Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; TP53 Regulates Transcription of DNA Repair Genes"	"Initiation of transcription and translation elongation at the HIV-1 LTR"	"15"	"0"	"90.9"	"106.2"	"262.3"	"88.8"	"110.4"	"92.7"	"394.3"	"105.1"	"154.4"	"120.3"	"139.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2S7"	"Polymerase delta-interacting protein 2 OS=Homo sapiens OX=9606 GN=POLDIP2 PE=1 SV=1"	"13"	"4"	"10"	"4"	"368"	"42.0"	"8.63"	"1915.35"	"16.70"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytoskeleton;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity"	"Pf04379, Pf08755"	"26073"	"ENSG00000004142"	"POLDIP2"	"B2R846; hsa:26073; Q96JE4; Q9Y2S7"	""	""	"0"	"0"	"289.1"	"467.9"	"1347.6"	"435.6"	"444.2"	"460.3"	"1598.2"	"327.7"	"480.5"	"318.1"	"338.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99714"	"3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3"	"18"	"4"	"10"	"4"	"261"	"26.9"	"7.78"	"1949.88"	"16.69"	"4"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"plasma membrane;other membranes;mitochondrion;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00106"	"3028"	"ENSG00000072506"	"HSD17B10"	"hsa:3028; Q5H927; Q6IBS9; Q8TCV9; Q96HD5; Q99714"	"Branched-chain amino acid catabolism; tRNA processing in the mitochondrion; tRNA modification in the mitochondrion; rRNA processing in the mitochondrion"	"Alzheimer's disease and miRNA effects; Valproic acid pathway; Alzheimer's disease"	"7"	"0"	"250.9"	"285.7"	"1165.9"	"268.3"	"248.8"	"206.4"	"1142.7"	"158.7"	"206.5"	"171.5"	"197.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UJS0"	"Calcium-binding mitochondrial carrier protein Aralar2 OS=Homo sapiens OX=9606 GN=SLC25A13 PE=1 SV=2"	"8"	"4"	"10"	"4"	"675"	"74.1"	"8.62"	"2161.26"	"16.67"	"4"	"4"	"other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00153"	"10165"	"ENSG00000004864"	"SLC25A13"	"hsa:10165; O14566; O14575; Q546F9; Q9NZW1; Q9UJS0; Q9UNI7"	"Mitochondrial protein import; Gluconeogenesis; Aspartate and asparagine metabolism"	""	"3"	"0"	"161.2"	"167.1"	"626.9"	"151.8"	"141.3"	"113.3"	"635.2"	"72.1"	"106.7"	"78.4"	"83.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49406"	"39S ribosomal protein L19, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL19 PE=1 SV=2"	"19"	"5"	"9"	"5"	"292"	"33.5"	"9.50"	"1563.68"	"16.63"	"4"	"5"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf01245"	"9801"	"ENSG00000115364"	"MRPL19"	"hsa:9801; P49406; Q53TX9; Q96Q52"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"Cytoplasmic ribosomal proteins"	"4"	"0"	"178.1"	"198.5"	"543.3"	"177.2"	"158.6"	"145.7"	"613.9"	"138.3"	"160.2"	"148.4"	"155.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q2NL82"	"Pre-rRNA-processing protein TSR1 homolog OS=Homo sapiens OX=9606 GN=TSR1 PE=1 SV=1"	"12"	"6"	"10"	"6"	"804"	"91.8"	"7.42"	"1723.05"	"16.59"	"5"	"5"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04950, Pf08142"	"55720"	"ENSG00000167721"	"TSR1"	"hsa:55720; Q2NL82; Q8WUY5; Q9NVT0; Q9P2E6"	"Major pathway of rRNA processing in the nucleolus and cytosol"	""	"1"	"0"	"223.9"	"210.4"	"655.6"	"223.7"	"203.3"	"176.7"	"617.3"	"88.3"	"169.6"	"144.2"	"132.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13867"	"Bleomycin hydrolase OS=Homo sapiens OX=9606 GN=BLMH PE=1 SV=1"	"14"	"4"	"7"	"4"	"455"	"52.5"	"6.27"	"1029.84"	"16.59"	"3"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf03051"	"642"	"ENSG00000108578"	"BLMH"	"B2R796; hsa:642; Q13867; Q53F86; Q9UER9"	"Antigen processing: Ubiquitination & Proteasome degradation"	""	"1"	"0"	"515.0"	"323.1"	"919.2"	"193.8"	"218.6"	"156.5"	"1094.0"	"151.2"	"189.6"	"161.2"	"160.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96E39"	"RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1"	"14"	"4"	"9"	"1"	"390"	"42.1"	"9.89"	"1498.65"	"16.55"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf08081"	"494115"	"ENSG00000213516"	"RBMXL1"	"hsa:494115; Q96E39"	""	""	"0"	"0"	"52.5"	"47.1"	"189.3"	"53.8"	"55.3"	"40.5"	"222.0"	"34.4"	"49.1"	"50.2"	"49.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQ52"	"Zinc phosphodiesterase ELAC protein 2 OS=Homo sapiens OX=9606 GN=ELAC2 PE=1 SV=2"	"10"	"6"	"11"	"6"	"826"	"92.2"	"7.90"	"2088.00"	"16.55"	"6"	"5"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf12706, Pf13691"	"60528"	"ENSG00000006744"	"ELAC2"	"B4DPL9; hsa:60528; Q6IA94; Q9BQ52; Q9HAS8; Q9HAS9; Q9NVT1"	"tRNA processing in the nucleus; tRNA processing in the mitochondrion; rRNA processing in the mitochondrion; tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis"	""	"4"	"0"	"120.1"	"145.8"	"512.4"	"154.4"	"134.8"	"108.4"	"573.6"	"83.7"	"171.7"	"185.9"	"257.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6UB35"	"Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1"	"7"	"5"	"10"	"4"	"978"	"105.7"	"8.06"	"2282.72"	"16.47"	"4"	"4"	"other metabolic processes;developmental processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf00763, Pf01268, Pf02882"	"25902"	"ENSG00000120254"	"MTHFD1L"	"hsa:25902; Q2TBF3; Q6UB35; Q8WVW0; Q96HG8; Q9H789; Q9UFU8"	"Metabolism of folate and pterines"	"One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways"	"3"	"0"	"160.8"	"209.5"	"735.3"	"218.6"	"210.5"	"141.2"	"930.8"	"103.4"	"166.0"	"141.6"	"170.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P33176"	"Kinesin-1 heavy chain OS=Homo sapiens OX=9606 GN=KIF5B PE=1 SV=1"	"7"	"5"	"9"	"5"	"963"	"109.6"	"6.51"	"1415.35"	"16.47"	"4"	"5"	"cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225"	"3799"	"ENSG00000170759"	"KIF5B"	"A0AVB2; hsa:3799; P33176; Q5VZ85"	"COPI-dependent Golgi-to-ER retrograde traffic; MHC class II antigen presentation; Kinesins; Insulin processing; Nuclear events stimulated by ALK signaling in cancer; RHO GTPases activate KTN1"	"Alzheimer's disease and miRNA effects; Envelope proteins and their potential roles in EDMD physiopathology; Insulin signaling; CCL18 signaling pathway; Alzheimer's disease"	"12"	"0"	"327.0"	"323.9"	"1482.1"	"310.6"	"256.4"	"177.4"	"1545.3"	"127.9"	"179.4"	"152.1"	"143.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P36873"	"Serine/threonine-protein phosphatase PP1-gamma catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CC PE=1 SV=1"	"21"	"5"	"8"	"1"	"323"	"37.0"	"6.54"	"1157.34"	"16.30"	"3"	"5"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00149, Pf16891"	"5501"	"ENSG00000186298"	"PPP1CC"	"hsa:5501; P36873"	"Separation of Sister Chromatids; Triglyceride catabolism; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Circadian Clock; RAF activation; SHOC2 M1731 mutant abolishes MRAS complex function; Gain-of-function MRAS complexes activate RAF signaling; Downregulation of TGF-beta receptor signaling"	"Common pathways underlying drug addiction; Focal adhesion; Hippo-Merlin signaling dysregulation; Neuroinflammation and glutamatergic signaling"	"16"	"0"	"136.2"	"157.3"	"369.6"	"138.0"	"111.1"	"85.0"	"379.7"	"110.3"	"168.7"	"156.0"	"202.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P58876"	"Histone H2B type 1-D OS=Homo sapiens OX=9606 GN=H2BC5 PE=1 SV=2"	"42"	"5"	"10"	"1"	"126"	"13.9"	"10.32"	"1823.22"	"16.24"	"4"	"4"	""	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125"	"3017"	"ENSG00000158373"	"H2BC5"	"hsa:3017; P58876"	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Estrogen-dependent gene expression; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; Meiotic recombination; E3 ubiquitin ligases ubiquitinate target proteins; Amyloid fiber formation; Meiotic synapsis; HCMV Late Events; Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; HCMV Early Events; Transcriptional regulation by small RNAs; Deposition of new CENPA-containing nucleosomes at the centromere; B-WICH complex positively regulates rRNA expression; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Formation of the beta-catenin:TCF transactivating complex; Oxidative Stress Induced Senescence; HDACs deacetylate histones; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Pre-NOTCH Transcription and Translation; Senescence-Associated Secretory Phenotype (SASP); HATs acetylate histones; RNA Polymerase I Promoter Escape; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Packaging Of Telomere Ends; Condensation of Prophase Chromosomes; DNA Damage/Telomere Stress Induced Senescence; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; Nonhomologous End-Joining (NHEJ); RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis"	""	"43"	"0"	"117.2"	"163.3"	"358.9"	"94.4"	"138.5"	"82.9"	"290.2"	"50.5"	"62.4"	"78.6"	"58.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A0FGR8"	"Extended synaptotagmin-2 OS=Homo sapiens OX=9606 GN=ESYT2 PE=1 SV=1"	"4"	"3"	"10"	"3"	"921"	"102.3"	"9.26"	"1763.83"	"16.19"	"3"	"3"	"cell organization and biogenesis;transport"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00168, Pf17047"	"57488"	"ENSG00000117868"	"ESYT2"	"A0FGR8; A4D229; hsa:57488; Q69YJ2; Q6UKI4; Q6ZTU0; Q6ZVU1; Q9BQS0; Q9NW47; Q9ULJ2"	"Glycosphingolipid metabolism"	""	"1"	"0"	"73.5"	"82.0"	"256.8"	"99.7"	"119.6"	"174.0"	"391.6"	"165.6"	"359.9"	"367.0"	"401.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P27708"	"CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3"	"4"	"8"	"13"	"8"	"2225"	"242.8"	"6.46"	"2261.31"	"16.18"	"7"	"6"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00117, Pf00185, Pf00988, Pf01979, Pf02142, Pf02729, Pf02786, Pf02787"	"790"	"ENSG00000084774"	"CAD"	"D6W552; hsa:790; P27708; Q6P0Q0; Q96CK3"	"Pyrimidine biosynthesis"	"Endothelin pathways; Amino acid metabolism; Pyrimidine metabolism"	"4"	"0"	"220.7"	"225.2"	"916.1"	"261.0"	"252.9"	"194.3"	"880.8"	"139.4"	"186.1"	"224.1"	"187.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62805"	"Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2"	"45"	"5"	"11"	"5"	"103"	"11.4"	"11.36"	"1740.16"	"16.17"	"4"	"5"	"cell organization and biogenesis;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf15511"	"121504; 554313; 8294; 8359; 8360; 8361; 8362; 8363; 8364; 8365; 8366; 8367; 8368; 8370"	"ENSG00000158406; ENSG00000197061; ENSG00000197238; ENSG00000197837; ENSG00000270276; ENSG00000270882; ENSG00000273542; ENSG00000274618; ENSG00000275126; ENSG00000276180; ENSG00000276966; ENSG00000277157; ENSG00000278637; ENSG00000278705"	"H4C1; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9"	"A2VCL0; hsa:121504; hsa:554313; hsa:8294; hsa:8359; hsa:8360; hsa:8361; hsa:8362; hsa:8363; hsa:8364; hsa:8365; hsa:8366; hsa:8367; hsa:8368; hsa:8370; P02304; P02305; P62805; Q6DRA9; Q6FGB8; Q6NWP7"	"HDACs deacetylate histones; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Oxidative Stress Induced Senescence; Senescence-Associated Secretory Phenotype (SASP); RNA Polymerase I Promoter Opening; RUNX1 regulates transcription of genes involved in differentiation of HSCs; SUMOylation of chromatin organization proteins; HCMV Late Events; Amyloid fiber formation; Meiotic synapsis; HCMV Early Events; Transcriptional regulation by small RNAs; Deposition of new CENPA-containing nucleosomes at the centromere; B-WICH complex positively regulates rRNA expression; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Formation of the beta-catenin:TCF transactivating complex; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Pre-NOTCH Transcription and Translation; RMTs methylate histone arginines; HDMs demethylate histones; PKMTs methylate histone lysines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; HATs acetylate histones; RNA Polymerase I Promoter Escape; Meiotic recombination; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Packaging Of Telomere Ends; Condensation of Prophase Chromosomes; DNA Damage/Telomere Stress Induced Senescence; DNA methylation; Nonhomologous End-Joining (NHEJ); Transcriptional regulation of granulopoiesis"	"Gastric cancer network 1; Histone modifications; 22q11.2 copy number variation syndrome; Male infertility; 11p11.2 copy number variation syndrome ; Type II interferon signaling"	"51"	"0"	"392.4"	"478.9"	"1779.5"	"478.7"	"429.5"	"312.3"	"1811.6"	"198.2"	"295.9"	"229.4"	"216.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61201"	"COP9 signalosome complex subunit 2 OS=Homo sapiens OX=9606 GN=COPS2 PE=1 SV=1"	"13"	"5"	"9"	"5"	"443"	"51.6"	"5.53"	"2117.73"	"16.17"	"5"	"4"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01399"	"9318"	"ENSG00000166200"	"COPS2"	"hsa:9318; O88950; P61201; Q15647; Q6FGP4; Q9BY54; Q9R249; Q9UNI2; Q9UNQ5"	"Neddylation; Cargo recognition for clathrin-mediated endocytosis; Formation of TC-NER Pre-Incision Complex; RHOBTB1 GTPase cycle; DNA Damage Recognition in GG-NER"	"Ciliary landscape"	"6"	"0"	"354.7"	"423.4"	"1236.1"	"370.6"	"337.8"	"274.6"	"1437.9"	"226.1"	"332.4"	"295.3"	"314.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62633"	"Cellular nucleic acid-binding protein OS=Homo sapiens OX=9606 GN=CNBP PE=1 SV=1"	"25"	"4"	"8"	"4"	"177"	"19.5"	"7.71"	"587.27"	"16.16"	"1"	"4"	"DNA metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00098"	"7555"	"ENSG00000169714"	"CNBP"	"A8K7V4; B2RAV9; B4DP17; D3DNB9; D3DNC0; D3DNC1; E9PDR7; hsa:7555; P20694; P62633; Q4JGY0; Q4JGY1; Q5QJR0; Q5U0E9; Q6PJI7; Q96NV3"	"SARS-CoV-2 activates/modulates innate and adaptive immune responses"	""	"1"	"0"	"190.7"	"179.5"	"875.2"	"249.6"	"197.2"	"162.8"	"983.9"	"113.3"	"176.2"	"139.1"	"115.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P26368"	"Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4"	"17"	"6"	"9"	"6"	"475"	"53.5"	"9.09"	"1723.62"	"16.15"	"5"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"11338"	"ENSG00000063244"	"U2AF2"	"hsa:11338; P26368; Q96HC5"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"mRNA processing"	"5"	"0"	"290.0"	"288.5"	"1118.0"	"276.0"	"263.2"	"233.4"	"1136.6"	"146.1"	"209.1"	"182.8"	"202.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P48634"	"Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3"	"3"	"5"	"9"	"4"	"2157"	"228.7"	"9.45"	"1354.13"	"16.13"	"4"	"5"	"other biological processes"	"plasma membrane;other membranes;cytosol;nucleus"	""	"Pf07001"	"7916"	"ENSG00000204469; ENSG00000206427; ENSG00000225164; ENSG00000225748; ENSG00000226618; ENSG00000231370; ENSG00000231825"	"PRRC2A"	"B0UX77; B0UZE9; B0UZL3; hsa:7916; O95875; P48634; Q05BK4; Q4LE37; Q5SQ29; Q5SQ30; Q5ST84; Q5STX6; Q5STX7; Q68DW9; Q6P9P7; Q6PIN1; Q8MGQ9; Q96QC6"	""	""	"0"	"0"	"107.0"	"109.2"	"428.7"	"125.6"	"117.1"	"101.1"	"630.0"	"160.5"	"272.7"	"219.6"	"208.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08195"	"4F2 cell-surface antigen heavy chain OS=Homo sapiens OX=9606 GN=SLC3A2 PE=1 SV=3"	"9"	"5"	"10"	"5"	"630"	"68.0"	"5.01"	"1701.29"	"16.12"	"5"	"5"	"other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;nucleus;other cytoplasmic organelle;other cell component"	"transporter activity;nucleic acid binding activity"	"Pf00128, Pf16028"	"6520"	"ENSG00000168003"	"SLC3A2"	"hsa:6520; J3KPF3; P08195; Q13543"	"Tryptophan catabolism; Basigin interactions; Amino acid transport across the plasma membrane; Defective SLC7A7 causes lysinuric protein intolerance (LPI)"	"mRNA, protein, and metabolite inducation pathway by cyclosporin A; Ferroptosis; Proximal tubule transport; Pleural mesothelioma"	"8"	"0"	"180.6"	"159.0"	"477.0"	"139.9"	"124.9"	"105.0"	"510.0"	"81.6"	"93.6"	"83.8"	"67.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30048"	"Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3"	"20"	"4"	"7"	"4"	"256"	"27.7"	"7.78"	"1425.80"	"16.10"	"3"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00578, Pf10417"	"10935"	"ENSG00000165672"	"PRDX3"	"B2R7Z0; D3DRC9; E9PH29; hsa:10935; P30048; P35690; Q0D2H1; Q13776; Q5T5V2; Q96HK4"	"Detoxification of Reactive Oxygen Species"	"Selenium micronutrient network"	"2"	"0"	"149.8"	"170.6"	"1070.1"	"158.8"	"139.3"	"91.7"	"1592.1"	"75.0"	"99.7"	"76.3"	"60.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q07955"	"Serine/arginine-rich splicing factor 1 OS=Homo sapiens OX=9606 GN=SRSF1 PE=1 SV=2"	"25"	"4"	"6"	"4"	"248"	"27.7"	"10.36"	"629.25"	"16.03"	"2"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6426"	"ENSG00000136450"	"SRSF1"	"B2R6Z7; D3DTZ3; hsa:6426; Q07955; Q13809"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; mRNA Splicing - Minor Pathway"	"mRNA processing"	"7"	"0"	"342.7"	"395.9"	"1244.2"	"313.5"	"344.3"	"260.1"	"1541.8"	"183.0"	"300.1"	"226.4"	"226.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WWM7"	"Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2"	"6"	"5"	"8"	"5"	"1075"	"113.3"	"8.59"	"1566.95"	"16.02"	"4"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf06741, Pf07145, Pf14438"	"11273"	"ENSG00000168488"	"ATXN2L"	"A8K1R6; B9EGM2; E9PAR9; hsa:11273; O95135; Q63ZY4; Q6NVJ8; Q6PJW6; Q8IU61; Q8IU95; Q8WWM3; Q8WWM4; Q8WWM5; Q8WWM6; Q8WWM7; Q99703"	""	"16p11.2 distal deletion syndrome"	"1"	"0"	"511.9"	"458.8"	"1344.2"	"444.8"	"425.7"	"362.3"	"1913.8"	"406.8"	"635.3"	"526.4"	"489.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61011"	"Signal recognition particle 54 kDa protein OS=Homo sapiens OX=9606 GN=SRP54 PE=1 SV=1"	"13"	"5"	"10"	"5"	"504"	"55.7"	"8.75"	"2005.48"	"15.99"	"5"	"5"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00448, Pf02881, Pf02978"	"6729"	"ENSG00000100883"	"SRP54"	"B2R759; B4DUW6; hsa:6729; P13624; P61011"	"SRP-dependent cotranslational protein targeting to membrane"	"VEGFA-VEGFR2 signaling; mRNA processing"	"3"	"0"	"142.2"	"132.3"	"514.1"	"98.3"	"91.2"	"63.4"	"522.4"	"44.1"	"60.7"	"50.1"	"48.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82673"	"28S ribosomal protein S35, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS35 PE=1 SV=1"	"18"	"4"	"9"	"4"	"323"	"36.8"	"8.24"	"1132.64"	"15.94"	"3"	"4"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf10213"	"60488"	"ENSG00000061794"	"MRPS35"	"hsa:60488; P82673; Q32LZ1; Q6P4C6; Q7L1M6; Q8NBP4; Q96AI0; Q9H044; Q9HC14; Q9P1R5"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"230.9"	"252.8"	"713.2"	"223.9"	"226.1"	"199.6"	"865.0"	"142.9"	"181.0"	"155.0"	"175.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2A7"	"Nck-associated protein 1 OS=Homo sapiens OX=9606 GN=NCKAP1 PE=1 SV=1"	"5"	"6"	"11"	"6"	"1128"	"128.7"	"6.62"	"2354.15"	"15.85"	"6"	"5"	"cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	""	"Pf09735"	"10787"	"ENSG00000061676"	"NCKAP1"	"hsa:10787; O60329; Q53QN5; Q53S94; Q53Y35; Q9Y2A7"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; VEGFA-VEGFR2 Pathway"	"Exercise-induced circadian regulation; Regulation of actin cytoskeleton"	"9"	"0"	"446.2"	"453.6"	"1176.0"	"427.2"	"382.0"	"322.5"	"807.2"	"184.5"	"302.2"	"313.7"	"352.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UG63"	"ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2"	"10"	"5"	"10"	"5"	"623"	"71.2"	"7.37"	"1755.46"	"15.83"	"5"	"5"	""	""	"other molecular function"	"Pf00005, Pf12848"	"10061; 114483834"	"ENSG00000033050"	"ABCF2"	"hsa:10061; hsa:114483834; O60864; Q75MJ0; Q75MJ1; Q96TE8; Q9UG63"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"112.2"	"120.3"	"378.8"	"99.1"	"110.3"	"87.5"	"382.4"	"44.9"	"66.9"	"45.7"	"46.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13868"	"Exosome complex component RRP4 OS=Homo sapiens OX=9606 GN=EXOSC2 PE=1 SV=2"	"16"	"3"	"8"	"3"	"293"	"32.8"	"7.50"	"1813.79"	"15.83"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf14382, Pf15985"	"23404"	"ENSG00000130713"	"EXOSC2"	"A3KFL3; A3KFL4; B4DKK6; hsa:23404; Q13868; Q9NUY4"	"Major pathway of rRNA processing in the nucleolus and cytosol; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	"Ciliary landscape"	"7"	"0"	"64.3"	"70.0"	"324.6"	"74.8"	"67.0"	"46.6"	"419.2"	"37.6"	"67.0"	"37.1"	"42.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6PI48"	"Aspartate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=DARS2 PE=1 SV=1"	"11"	"6"	"10"	"6"	"645"	"73.5"	"8.02"	"1810.26"	"15.72"	"5"	"5"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00152, Pf01336, Pf02938"	"55157"	"ENSG00000117593"	"DARS2"	"hsa:55157; Q6PI48"	"Mitochondrial tRNA aminoacylation"	""	"1"	"0"	"457.8"	"482.2"	"1615.9"	"463.9"	"350.0"	"304.0"	"1707.2"	"305.2"	"379.1"	"315.3"	"357.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01844"	"RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1"	"7"	"4"	"9"	"4"	"656"	"68.4"	"9.33"	"1551.69"	"15.67"	"3"	"3"	"RNA metabolism OR transcription;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00076, Pf00641"	"2130"	"ENSG00000182944"	"EWSR1"	"B0QYK1; hsa:2130; Q01844; Q5THL0; Q92635; Q96FE8; Q96MN4; Q96MX4; Q9BWA2"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"850.7"	"905.4"	"2280.5"	"947.2"	"822.4"	"832.3"	"2244.9"	"378.4"	"572.2"	"459.2"	"493.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16630"	"Cleavage and polyadenylation specificity factor subunit 6 OS=Homo sapiens OX=9606 GN=CPSF6 PE=1 SV=2"	"14"	"4"	"6"	"4"	"551"	"59.2"	"7.15"	"710.80"	"15.59"	"2"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00076"	"11052"	"ENSG00000111605"	"CPSF6"	"A8K7K9; hsa:11052; Q16630; Q53ES1; Q9BSJ7; Q9BW18"	"Signaling by cytosolic FGFR1 fusion mutants; Signaling by FGFR1 in disease"	""	"2"	"0"	"56.9"	"55.9"	"149.4"	"45.5"	"59.4"	"50.4"	"196.3"	"31.8"	"49.5"	"42.4"	"49.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82663"	"28S ribosomal protein S25, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS25 PE=1 SV=1"	"27"	"4"	"10"	"4"	"173"	"20.1"	"8.82"	"1636.53"	"15.58"	"4"	"4"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf05047"	"64432"	"ENSG00000131368"	"MRPS25"	"B4DFJ5; B4DQG6; hsa:64432; P82663; Q9H7P5"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"194.7"	"190.3"	"578.3"	"190.5"	"187.5"	"154.7"	"517.6"	"73.8"	"114.0"	"101.4"	"87.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P36776"	"Lon protease homolog, mitochondrial OS=Homo sapiens OX=9606 GN=LONP1 PE=1 SV=2"	"5"	"5"	"10"	"5"	"959"	"106.4"	"6.39"	"1722.10"	"15.56"	"5"	"5"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00004, Pf02190, Pf05362"	"9361"	"ENSG00000196365"	"LONP1"	"B3KPH8; D6W635; E5KMH8; F5GZ27; hsa:9361; P36776; P36777; Q8N8K8; Q9UQ95"	""	""	"0"	"0"	"83.8"	"80.4"	"448.8"	"77.1"	"69.4"	"57.3"	"368.8"	"29.0"	"28.9"	"47.7"	"31.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60900"	"Proteasome subunit alpha type-6 OS=Homo sapiens OX=9606 GN=PSMA6 PE=1 SV=1"	"26"	"6"	"10"	"6"	"246"	"27.4"	"6.76"	"1851.68"	"15.52"	"5"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00227, Pf10584"	"5687"	"ENSG00000100902"	"PSMA6"	"B2R7J9; B4DQR4; B4DXJ9; hsa:5687; P34062; P60900; Q6IB60"	"Separation of Sister Chromatids; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"62"	"0"	"274.0"	"280.5"	"1093.6"	"245.7"	"145.5"	"124.3"	"997.3"	"236.6"	"277.6"	"254.1"	"305.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBT2"	"SUMO-activating enzyme subunit 2 OS=Homo sapiens OX=9606 GN=UBA2 PE=1 SV=2"	"11"	"5"	"8"	"5"	"640"	"71.2"	"5.29"	"1068.13"	"15.45"	"3"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00899, Pf14732, Pf16195"	"10054"	"ENSG00000126261"	"UBA2"	"B3KWB9; hsa:10054; O95605; Q59H87; Q6IBP6; Q9NTJ1; Q9UBT2; Q9UED2"	"SUMO is conjugated to E1 (UBA2:SAE1); SUMO is transferred from E1 to E2 (UBE2I, UBC9)"	""	"2"	"0"	"228.2"	"235.3"	"958.2"	"228.0"	"227.8"	"139.5"	"1138.5"	"163.2"	"165.0"	"119.1"	"86.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13813"	"Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3"	"2"	"4"	"8"	"4"	"2472"	"284.4"	"5.35"	"1736.42"	"15.45"	"4"	"4"	"cell organization and biogenesis"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00018, Pf00435, Pf08726, Pf13499"	"6709"	"ENSG00000197694"	"SPTAN1"	"hsa:6709; Q13186; Q13813; Q15324; Q16606; Q59EF1; Q5VXV5; Q5VXV6; Q7Z6M5; Q9P0V0"	"Neutrophil degranulation; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Interaction between L1 and Ankyrins; RHOV GTPase cycle; COPI-mediated anterograde transport; RHOU GTPase cycle; Nephrin family interactions; RAF/MAP kinase cascade; NCAM signaling for neurite out-growth; Caspase-mediated cleavage of cytoskeletal proteins"	"Fas ligand pathway and stress induction of heat shock proteins"	"12"	"0"	"101.2"	"103.1"	"401.4"	"102.7"	"91.3"	"70.2"	"390.1"	"47.7"	"70.9"	"68.5"	"113.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13442"	"28 kDa heat- and acid-stable phosphoprotein OS=Homo sapiens OX=9606 GN=PDAP1 PE=1 SV=1"	"34"	"6"	"11"	"6"	"181"	"20.6"	"8.87"	"2513.52"	"15.43"	"6"	"5"	"signal transduction"	"non-structural extracellular;plasma membrane;other membranes;cytosol;other cell component"	""	"Pf10252"	"11333"	"ENSG00000106244"	"PDAP1"	"D6W5S5; hsa:11333; Q13442; Q92906"	"Neutrophil degranulation"	""	"1"	"0"	"919.0"	"900.3"	"2664.9"	"903.3"	"857.2"	"733.4"	"3903.5"	"741.7"	"1474.0"	"1069.3"	"1043.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A6NHR9"	"Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2"	"3"	"5"	"10"	"5"	"2005"	"226.2"	"7.30"	"1557.19"	"15.39"	"5"	"5"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06470, Pf13589"	"23347"	"ENSG00000101596"	"SMCHD1"	"A6NHR9; hsa:23347; O75141; Q6AHX6; Q6ZTQ8; Q9H6Q2; Q9UG39"	""	""	"0"	"0"	"126.0"	"137.6"	"472.8"	"138.4"	"143.6"	"118.9"	"468.5"	"53.5"	"74.5"	"50.6"	"54.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23526"	"Adenosylhomocysteinase OS=Homo sapiens OX=9606 GN=AHCY PE=1 SV=4"	"12"	"5"	"10"	"5"	"432"	"47.7"	"6.34"	"1786.67"	"15.36"	"5"	"5"	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00670, Pf05221"	"191"	"ENSG00000101444"	"AHCY"	"A8K307; B3KUN3; E1P5P2; F5H737; hsa:191; P23526; Q96A36"	"Methylation; Sulfur amino acid metabolism; Metabolism of ingested SeMet, Sec, MeSec into H2Se; Defective AHCY causes HMAHCHD"	"Folate metabolism; Trans-sulfuration pathway; One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways; Methionine de novo and salvage pathway; Ethanol effects on histone modifications"	"10"	"0"	"459.4"	"567.9"	"2444.0"	"499.1"	"407.3"	"324.6"	"3612.6"	"304.1"	"338.0"	"272.9"	"250.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NSE4"	"Isoleucine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=IARS2 PE=1 SV=2"	"5"	"4"	"9"	"4"	"1012"	"113.7"	"7.20"	"1190.83"	"15.33"	"3"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00133, Pf06827, Pf08264"	"55699"	"ENSG00000067704"	"IARS2"	"B2RPG8; hsa:55699; Q1M2P9; Q6PI85; Q7L439; Q86WU9; Q96D91; Q9H9Q8; Q9NSE4; Q9NW42"	"Mitochondrial tRNA aminoacylation"	""	"1"	"0"	"138.2"	"155.2"	"661.3"	"150.5"	"151.2"	"97.8"	"714.3"	"80.8"	"98.2"	"76.9"	"70.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q00169"	"Phosphatidylinositol transfer protein alpha isoform OS=Homo sapiens OX=9606 GN=PITPNA PE=1 SV=2"	"20"	"4"	"7"	"3"	"270"	"31.8"	"6.55"	"1159.53"	"15.33"	"3"	"4"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf02121"	"5306"	"ENSG00000174238"	"PITPNA"	"hsa:5306; Q00169"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Role of second messengers in netrin-1 signaling"	""	"2"	"0"	"128.5"	"148.1"	"459.6"	"166.9"	"179.4"	"191.9"	"560.5"	"83.1"	"171.6"	"121.8"	"81.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15347"	"High mobility group protein B3 OS=Homo sapiens OX=9606 GN=HMGB3 PE=1 SV=4"	"36"	"7"	"11"	"7"	"200"	"23.0"	"8.37"	"3022.30"	"15.30"	"7"	"4"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00505, Pf09011"	"3149"	"ENSG00000029993"	"HMGB3"	"hsa:3149; O15347; O95556; Q6NS40"	""	""	"0"	"0"	"872.9"	"861.1"	"3274.5"	"878.3"	"537.0"	"531.2"	"2553.2"	"336.0"	"643.1"	"531.5"	"545.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P20674"	"Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A PE=1 SV=2"	"33"	"4"	"8"	"4"	"150"	"16.8"	"6.79"	"1730.19"	"15.30"	"4"	"4"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf02284"	"9377"	"ENSG00000178741"	"COX5A"	"hsa:9377; P20674; P30045; Q8TB65"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex IV assembly; Arachidonate epoxygenase / epoxide hydrolase"	"7"	"0"	"254.1"	"321.3"	"1389.1"	"265.9"	"215.1"	"172.0"	"1601.5"	"123.0"	"172.3"	"103.4"	"139.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75643"	"U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2"	"3"	"6"	"9"	"6"	"2136"	"244.4"	"6.06"	"1556.59"	"15.25"	"4"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00270, Pf00271, Pf02889, Pf18149"	"23020"	"ENSG00000144028"	"SNRNP200"	"hsa:23020; O75643; O94884; Q6NZY0; Q6PX59; Q8NBE6; Q96IF2; Q9H7S0"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"2q11.2 copy number variation syndrome"	"3"	"0"	"272.6"	"299.5"	"808.7"	"252.1"	"246.7"	"192.6"	"791.0"	"166.2"	"209.3"	"195.6"	"198.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51572"	"B-cell receptor-associated protein 31 OS=Homo sapiens OX=9606 GN=BCAP31 PE=1 SV=3"	"23"	"7"	"12"	"7"	"246"	"28.0"	"8.44"	"2662.89"	"15.25"	"7"	"5"	"cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf05529, Pf18035"	"10134"	"ENSG00000185825"	"BCAP31"	"B3KQ79; D3DWV5; hsa:10134; P51572; Q13836; Q96CF0"	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC; RHOA GTPase cycle; Apoptotic cleavage of cellular proteins"	""	"4"	"0"	"619.5"	"696.7"	"2422.6"	"631.1"	"575.3"	"429.1"	"3522.3"	"306.0"	"535.8"	"382.4"	"343.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49755"	"Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2"	"17"	"3"	"8"	"3"	"219"	"25.0"	"7.44"	"1799.74"	"15.23"	"3"	"3"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"transporter activity;other molecular function"	"Pf01105"	"10972"	"ENSG00000170348"	"TMED10"	"B2R605; hsa:10972; P49755; Q15602; Q16536; Q86TC2; Q86TS5"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport; COPII-mediated vesicle transport; Cargo concentration in the ER"	"mRNA processing"	"5"	"0"	"312.1"	"320.5"	"1427.5"	"252.6"	"211.7"	"133.6"	"1552.2"	"99.7"	"139.6"	"108.8"	"108.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13995"	"Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD2 PE=1 SV=2"	"17"	"5"	"8"	"5"	"350"	"37.9"	"8.73"	"1333.64"	"15.21"	"3"	"4"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00763, Pf02882"	"10797"	"ENSG00000065911"	"MTHFD2"	"hsa:10797; P13995; Q53G90; Q53GV5; Q53S36; Q7Z650"	"Metabolism of folate and pterines"	"Folate metabolism; One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways"	"4"	"0"	"424.4"	"443.1"	"1291.8"	"392.4"	"394.2"	"381.5"	"2383.9"	"539.5"	"860.1"	"673.5"	"748.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5D862"	"Filaggrin-2 OS=Homo sapiens OX=9606 GN=FLG2 PE=1 SV=1"	"3"	"4"	"9"	"4"	"2391"	"247.9"	"8.31"	"1191.79"	"15.16"	"3"	"4"	"cell adhesion;other biological processes"	"non-structural extracellular;plasma membrane;other cell component"	"other molecular function"	"Pf01023"	"388698"	"ENSG00000143520"	"FLG2"	"hsa:388698; Q5D862; Q9H4U1"	"Neutrophil degranulation"	""	"1"	"0"	"1007.3"	"423.4"	"155.3"	"48.3"	"29.6"	"50.5"	"68.3"	"38.6"	"16.3"	"19.9"	"25.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBL3"	"Set1/Ash2 histone methyltransferase complex subunit ASH2 OS=Homo sapiens OX=9606 GN=ASH2L PE=1 SV=1"	"10"	"4"	"7"	"4"	"628"	"68.7"	"5.69"	"1277.93"	"15.15"	"3"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00622"	"9070"	"ENSG00000129691"	"ASH2L"	"A8K7C3; D3DSW9; hsa:9070; O60659; O60660; Q96B62; Q9UBL3"	"Deactivation of the beta-catenin transactivating complex; Formation of the beta-catenin:TCF transactivating complex; Activation of anterior HOX genes in hindbrain development during early embryogenesis; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Formation of WDR5-containing histone-modifying complexes; PKMTs methylate histone lysines"	"Kleefstra syndrome"	"7"	"0"	"127.3"	"120.1"	"372.8"	"114.5"	"108.4"	"84.6"	"387.7"	"62.8"	"94.7"	"76.5"	"70.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43852"	"Calumenin OS=Homo sapiens OX=9606 GN=CALU PE=1 SV=2"	"15"	"4"	"8"	"4"	"315"	"37.1"	"4.64"	"1448.49"	"15.07"	"4"	"4"	""	"non-structural extracellular;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf13833"	"813"	"ENSG00000128595"	"CALU"	"B3KPG9; D6QS48; D6QS49; D6QS50; D6QS51; D6QS52; D6QS53; D6QS54; D6QS55; D6QS56; D6QS57; D6QS58; D6QS59; F5H1Q9; F5H879; hsa:813; O43852; O60456; Q6FHB9; Q96RL3; Q9NR43"	"Platelet degranulation ; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation"	"NOTCH1 regulation of endothelial cell calcification; VEGFA-VEGFR2 signaling"	"5"	"0"	"164.2"	"211.6"	"580.0"	"199.6"	"214.3"	"178.1"	"629.5"	"116.5"	"197.0"	"190.6"	"197.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95747"	"Serine/threonine-protein kinase OSR1 OS=Homo sapiens OX=9606 GN=OXSR1 PE=1 SV=1"	"12"	"5"	"7"	"5"	"527"	"58.0"	"6.43"	"956.07"	"15.07"	"3"	"4"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf12202"	"9943"	"ENSG00000172939"	"OXSR1"	"hsa:9943; O95747; Q3LR53; Q7Z501; Q9UPQ1"	""	""	"0"	"0"	"130.3"	"114.4"	"403.3"	"118.7"	"137.8"	"106.6"	"424.7"	"83.6"	"209.1"	"607.5"	"1881.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31942"	"Heterogeneous nuclear ribonucleoprotein H3 OS=Homo sapiens OX=9606 GN=HNRNPH3 PE=1 SV=2"	"15"	"4"	"8"	"4"	"346"	"36.9"	"6.87"	"1287.39"	"15.04"	"3"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf00076"	"3189"	"ENSG00000096746"	"HNRNPH3"	"A8K682; B3KRE1; hsa:3189; P31942; Q9BSX1; Q9NP53; Q9NP96; Q9NPA7; Q9NPI4; Q9UFU4; Q9Y4J5"	""	""	"0"	"0"	"97.7"	"104.3"	"287.7"	"79.3"	"104.0"	"67.6"	"344.0"	"51.6"	"69.4"	"53.1"	"63.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30837"	"Aldehyde dehydrogenase X, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH1B1 PE=1 SV=3"	"11"	"5"	"9"	"4"	"517"	"57.2"	"6.80"	"1947.38"	"15.02"	"5"	"4"	""	""	""	""	""	""	""	""	""	""	"0"	"1"	"284.9"	"354.7"	"1343.0"	"318.1"	"324.9"	"247.7"	"1542.2"	"199.7"	"252.6"	"172.1"	"163.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P10768"	"S-formylglutathione hydrolase OS=Homo sapiens OX=9606 GN=ESD PE=1 SV=2"	"20"	"4"	"6"	"4"	"282"	"31.4"	"7.02"	"582.56"	"14.98"	"2"	"4"	"other metabolic processes"	"cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00756"	"2098"	"ENSG00000139684"	"ESD"	"hsa:2098; P10768; Q5TBU8; Q5TBV0; Q5TBV2; Q9BVJ2"	"Glutathione conjugation"	"Phase I biotransformations, non P450"	"2"	"0"	"269.1"	"345.9"	"1469.4"	"324.2"	"291.6"	"220.3"	"1695.7"	"185.8"	"246.1"	"186.3"	"151.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6WKZ4"	"Rab11 family-interacting protein 1 OS=Homo sapiens OX=9606 GN=RAB11FIP1 PE=1 SV=3"	"5"	"5"	"7"	"5"	"1283"	"137.1"	"5.43"	"1450.99"	"14.95"	"3"	"4"	"transport;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00168, Pf09457"	"80223"	"ENSG00000156675"	"RAB11FIP1"	"hsa:80223; J3KNP0; Q307T1; Q6AZK4; Q6WKZ2; Q6WKZ4; Q6WKZ6; Q86YV4; Q8TDL1; Q9H642"	""	""	"0"	"0"	"74.8"	"72.5"	"258.6"	"81.5"	"74.4"	"59.2"	"392.3"	"229.3"	"713.3"	"900.0"	"1002.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30085"	"UMP-CMP kinase OS=Homo sapiens OX=9606 GN=CMPK1 PE=1 SV=3"	"19"	"4"	"10"	"4"	"196"	"22.2"	"5.57"	"1731.19"	"14.93"	"4"	"4"	"other metabolic processes"	"cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00406"	"51727"	"ENSG00000162368"	"CMPK1"	"B2R6S5; B4DPU7; E9PGI8; hsa:51727; P30085; Q53GB7; Q5SVZ0; Q96C07; Q9UBQ8; Q9UIA2"	"Interconversion of nucleotide di- and triphosphates"	"Pyrimidine metabolism"	"2"	"0"	"111.0"	"169.1"	"715.1"	"155.1"	"130.9"	"90.8"	"848.0"	"102.9"	"126.1"	"91.2"	"80.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11387"	"DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2"	"10"	"7"	"11"	"7"	"765"	"90.7"	"9.31"	"1652.43"	"14.90"	"6"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf01028, Pf02919, Pf14370"	"7150"	"ENSG00000198900"	"TOP1"	"A8KA78; E1P5W3; hsa:7150; O43256; P11387; Q12855; Q12856; Q15610; Q5TFY3; Q9UJN0"	"SUMOylation of DNA replication proteins"	"Ebola virus infection in host"	"2"	"0"	"320.1"	"291.2"	"955.2"	"331.1"	"348.3"	"306.3"	"680.8"	"173.7"	"1312.0"	"1742.6"	"1274.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30520"	"Adenylosuccinate synthetase isozyme 2 OS=Homo sapiens OX=9606 GN=ADSS2 PE=1 SV=3"	"13"	"4"	"7"	"4"	"456"	"50.1"	"6.55"	"867.55"	"14.89"	"3"	"4"	"other metabolic processes;other biological processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00709"	"159"	"ENSG00000035687"	"ADSS2"	"B1AQM5; hsa:159; P30520; Q96EG7"	"Purine ribonucleoside monophosphate biosynthesis"	""	"1"	"0"	"129.7"	"161.2"	"715.5"	"149.6"	"136.3"	"96.4"	"896.1"	"93.5"	"122.4"	"84.0"	"75.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NE71"	"ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2"	"5"	"4"	"10"	"3"	"845"	"95.9"	"6.80"	"1891.25"	"14.85"	"4"	"4"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00005, Pf12848"	"23"	"ENSG00000204574; ENSG00000206490; ENSG00000225989; ENSG00000231129; ENSG00000232169; ENSG00000236149; ENSG00000236342"	"ABCF1"	"A2BF75; hsa:23; O14897; Q69YP6; Q8NE71"	"ABC-family proteins mediated transport"	"IL-18 signaling pathway"	"2"	"1"	"488.7"	"467.7"	"1621.7"	"536.9"	"499.0"	"427.6"	"1571.0"	"229.2"	"432.3"	"428.3"	"427.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00264"	"Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3"	"28"	"8"	"11"	"8"	"195"	"21.7"	"4.70"	"2016.44"	"14.79"	"6"	"5"	"cell organization and biogenesis;other metabolic processes;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;mitochondrion;ER/Golgi;other cell component"	"other molecular function"	"Pf00173"	"10857"	"ENSG00000101856"	"PGRMC1"	"B7Z1L3; hsa:10857; O00264; Q9UGJ9"	"Neutrophil degranulation"	"Primary ovarian insufficiency"	"2"	"0"	"847.4"	"976.1"	"3863.5"	"867.4"	"766.9"	"572.0"	"5052.9"	"528.6"	"718.5"	"535.9"	"554.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62244"	"40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2"	"43"	"8"	"16"	"8"	"130"	"14.8"	"10.13"	"2806.16"	"14.77"	"8"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00410"	"6210"	"ENSG00000134419"	"RPS15A"	"hsa:6210; P39027; P39031; P62244; Q3MHD9; Q8C023; Q9BV24"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Response of EIF2AK4 (GCN2) to amino acid deficiency; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"2195.2"	"2423.9"	"7653.2"	"2415.0"	"1972.3"	"1870.3"	"6401.2"	"629.7"	"1075.8"	"809.6"	"774.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P17174"	"Aspartate aminotransferase, cytoplasmic OS=Homo sapiens OX=9606 GN=GOT1 PE=1 SV=3"	"14"	"3"	"5"	"3"	"413"	"46.2"	"7.01"	"981.58"	"14.73"	"2"	"3"	"other metabolic processes;signal transduction;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00155"	"2805"	"ENSG00000120053"	"GOT1"	"B2R6R7; B7Z7E9; hsa:2805; P17174; Q5VW80"	"Gluconeogenesis; Aspartate and asparagine metabolism; Methionine salvage pathway"	"Alanine and aspartate metabolism; Trans-sulfuration pathway; Amino acid metabolism; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; TCA cycle in senescence; Neuroinflammation and glutamatergic signaling; Glycolysis and gluconeogenesis"	"10"	"0"	"20.5"	"33.0"	"77.6"	"15.6"	"14.3"	"11.9"	"123.5"	"22.8"	"25.1"	"18.7"	"10.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14776"	"Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2"	"6"	"5"	"8"	"4"	"1098"	"123.8"	"8.65"	"1212.89"	"14.70"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00397, Pf01846"	"10915"	"ENSG00000113649"	"TCERG1"	"hsa:10915; O14776; Q2NKN2; Q59EA1"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"305.4"	"302.0"	"835.4"	"301.0"	"311.5"	"265.0"	"1120.6"	"288.5"	"421.8"	"296.3"	"332.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14974"	"Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2"	"8"	"7"	"12"	"7"	"876"	"97.1"	"4.78"	"2288.74"	"14.68"	"7"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;signal transduction;other biological processes"	"non-structural extracellular;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00514, Pf03810"	"3837"	"ENSG00000108424"	"KPNB1"	"B7ZAV6; D3DTT3; hsa:3837; Q14637; Q14974; Q53XN2; Q96J27"	"Neutrophil degranulation; Apoptosis induced DNA fragmentation; ISG15 antiviral mechanism; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Nuclear import of Rev protein; Interferon alpha/beta signaling; Regulation of cholesterol biosynthesis by SREBP (SREBF); SARS-CoV-1 activates/modulates innate immune responses; Assembly of the ORC complex at the origin of replication; Initiation of Nuclear Envelope (NE) Reformation; Postmitotic nuclear pore complex (NPC) reformation; Inhibition of nitric oxide production"	"Sterol regulatory element-binding proteins (SREBP) signaling; 22q11.2 copy number variation syndrome"	"15"	"0"	"553.8"	"551.3"	"2629.8"	"533.2"	"458.0"	"332.0"	"3090.7"	"226.3"	"345.0"	"258.6"	"250.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P28340"	"DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2"	"7"	"6"	"10"	"6"	"1107"	"123.6"	"7.03"	"1771.47"	"14.68"	"5"	"5"	"DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00136, Pf03104, Pf14260"	"5424"	"ENSG00000062822"	"POLD1"	"hsa:5424; P28340; Q8NER3; Q96H98"	"Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Removal of the Flap Intermediate; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta); Cytosolic iron-sulfur cluster assembly; Polymerase switching on the C-strand of the telomere; Polymerase switching"	"Homologous recombination; Pyrimidine metabolism; DNA replication; Base excision repair; Nucleotide excision repair; DNA repair pathways, full network; Progeria-associated lipodystrophy; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"27"	"0"	"62.8"	"78.7"	"230.7"	"77.3"	"74.7"	"64.4"	"295.5"	"44.8"	"100.1"	"108.7"	"164.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H0U4"	"Ras-related protein Rab-1B OS=Homo sapiens OX=9606 GN=RAB1B PE=1 SV=1"	"31"	"5"	"11"	"2"	"201"	"22.2"	"5.73"	"2433.03"	"14.64"	"5"	"4"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00071"	"81876"	"ENSG00000174903"	"RAB1B"	"A8K7S1; hsa:81876; Q9H0U4"	"COPI-mediated anterograde transport; COPII-mediated vesicle transport; COPI-dependent Golgi-to-ER retrograde traffic; RAB GEFs exchange GTP for GDP on RABs; RAB geranylgeranylation; Golgi Cisternae Pericentriolar Stack Reorganization"	""	"6"	"0"	"62.6"	"66.6"	"280.8"	"79.0"	"78.1"	"60.3"	"367.1"	"53.6"	"74.6"	"88.3"	"44.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P98179"	"RNA-binding protein 3 OS=Homo sapiens OX=9606 GN=RBM3 PE=1 SV=1"	"36"	"3"	"7"	"3"	"157"	"17.2"	"8.91"	"1039.55"	"14.58"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"translation activity"	"Pf00076"	"5935"	"ENSG00000102317"	"RBM3"	"hsa:5935; P98179"	""	""	"0"	"0"	"104.3"	"149.7"	"161.6"	"60.2"	"83.3"	"79.2"	"328.8"	"209.8"	"218.9"	"179.2"	"223.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25789"	"Proteasome subunit alpha type-4 OS=Homo sapiens OX=9606 GN=PSMA4 PE=1 SV=1"	"19"	"5"	"10"	"5"	"261"	"29.5"	"7.72"	"1617.00"	"14.56"	"5"	"5"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf00227, Pf10584"	"5685"	"ENSG00000041357"	"PSMA4"	"D3DW86; hsa:5685; P25789; Q53XP2; Q567Q5; Q8TBD1"	"MAPK6/MAPK4 signaling; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Exercise-induced circadian regulation; Alzheimer's disease"	"63"	"0"	"1145.8"	"714.8"	"2254.5"	"666.6"	"345.8"	"301.4"	"1758.4"	"350.4"	"356.6"	"340.2"	"404.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00273"	"DNA fragmentation factor subunit alpha OS=Homo sapiens OX=9606 GN=DFFA PE=1 SV=1"	"22"	"6"	"9"	"6"	"331"	"36.5"	"4.79"	"1433.50"	"14.52"	"4"	"5"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02017, Pf09033"	"1676"	"ENSG00000160049"	"DFFA"	"hsa:1676; O00273; Q5T6G5; Q5T6G6; Q96I97; Q9Y6C6"	"Apoptosis induced DNA fragmentation"	"Apoptosis; Fas ligand pathway and stress induction of heat shock proteins; Acute viral myocarditis"	"4"	"0"	"191.1"	"296.7"	"951.8"	"318.2"	"323.5"	"286.0"	"1209.2"	"197.1"	"310.8"	"235.3"	"218.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05114"	"Non-histone chromosomal protein HMG-14 OS=Homo sapiens OX=9606 GN=HMGN1 PE=1 SV=3"	"32"	"4"	"9"	"4"	"100"	"10.7"	"9.60"	"1283.42"	"14.48"	"3"	"4"	"cell organization and biogenesis;DNA metabolism;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01101"	"3150"	"ENSG00000205581"	"HMGN1"	"hsa:3150; P05114; Q3KQR8"	"Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	"ATM signaling in development and disease ; p38 MAPK signaling pathway; Pleural mesothelioma; Nucleotide excision repair in xeroderma pigmentosum"	"8"	"0"	"307.1"	"306.6"	"945.2"	"295.9"	"300.9"	"236.5"	"1529.2"	"328.6"	"577.1"	"471.0"	"595.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P0L0"	"Vesicle-associated membrane protein-associated protein A OS=Homo sapiens OX=9606 GN=VAPA PE=1 SV=3"	"27"	"4"	"9"	"3"	"249"	"27.9"	"8.62"	"1706.23"	"14.44"	"4"	"4"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00635"	"9218"	"ENSG00000101558"	"VAPA"	"A6NDZ0; D3DUI3; hsa:9218; O75453; Q5U0E7; Q9P0L0; Q9UBZ2"	"Neutrophil degranulation; Sphingolipid de novo biosynthesis; Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"	"Exercise-induced circadian regulation; Cholesterol metabolism"	"5"	"0"	"46.8"	"48.9"	"166.2"	"42.2"	"44.7"	"33.6"	"175.6"	"19.8"	"32.4"	"27.1"	"27.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15530"	"3-phosphoinositide-dependent protein kinase 1 OS=Homo sapiens OX=9606 GN=PDPK1 PE=1 SV=1"	"6"	"2"	"6"	"2"	"556"	"63.1"	"7.36"	"1576.11"	"14.41"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069, Pf14593"	"5170"	"ENSG00000140992"	"PDPK1"	"H0Y4Z0; hsa:5170; O15530; Q59EH6; Q6FI20; Q8IV52; Q9BRD5"	"Role of LAT2/NTAL/LAB on calcium mobilization; FCERI mediated NF-kB activation; Downstream TCR signaling; CLEC7A (Dectin-1) signaling; Constitutive Signaling by AKT1 E17K in Cancer; PIP3 activates AKT signaling; Regulation of TP53 Degradation; GPVI-mediated activation cascade; CD28 dependent PI3K/Akt signaling; G beta:gamma signalling through PI3Kgamma; RHO GTPases activate PKNs; Activation of AKT2; Integrin signaling; RSK activation; VEGFR2 mediated vascular permeability; VEGFR2 mediated cell proliferation; Estrogen-stimulated signaling through PRKCZ; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways"	"MicroRNAs in cardiomyocyte hypertrophy; Integrin-mediated cell adhesion; Thyroid stimulating hormone (TSH) signaling pathway; Glioblastoma signaling pathways; B cell receptor signaling pathway; Interleukin-11 signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Cardiac hypertrophic response; Focal adhesion; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Leptin-insulin signaling overlap; PPAR signaling pathway; Endometrial cancer; PI3K-Akt signaling pathway; EGF/EGFR signaling pathway; Head and neck squamous cell carcinoma; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; Modulators of TCR signaling and T cell activation; GDNF signaling; Primary ovarian insufficiency; A network map of Macrophage-stimulating protein (MSP) signaling; ErbB signaling pathway; T-cell receptor signaling pathway; Serotonin HTR1 group and FOS pathway"	"46"	"0"	"12.0"	"18.0"	"47.7"	"14.3"	"22.9"	"20.2"	"108.6"	"39.5"	"129.0"	"192.9"	"303.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NYL9"	"Tropomodulin-3 OS=Homo sapiens OX=9606 GN=TMOD3 PE=1 SV=1"	"16"	"4"	"8"	"4"	"352"	"39.6"	"5.19"	"1707.84"	"14.40"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton"	"cytoskeletal activity"	"Pf03250"	"29766"	"ENSG00000138594"	"TMOD3"	"B2R6G7; hsa:29766; Q9NT43; Q9NYL9; Q9NZR0"	"RND3 GTPase cycle; Striated Muscle Contraction; RHOBTB2 GTPase cycle"	"VEGFA-VEGFR2 signaling"	"4"	"0"	"205.6"	"232.5"	"637.0"	"228.8"	"244.2"	"190.5"	"749.9"	"132.5"	"210.2"	"182.4"	"147.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N1G4"	"Leucine-rich repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=LRRC47 PE=1 SV=1"	"9"	"4"	"7"	"4"	"583"	"63.4"	"8.28"	"1074.16"	"14.39"	"3"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	""	"other molecular function"	"Pf00560, Pf03483, Pf12799"	"57470"	"ENSG00000130764"	"LRRC47"	"hsa:57470; Q8N1G4; Q9ULN5"	""	""	"0"	"0"	"179.0"	"163.7"	"582.0"	"171.2"	"144.0"	"108.8"	"622.3"	"92.7"	"141.4"	"136.3"	"140.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P16402"	"Histone H1.3 OS=Homo sapiens OX=9606 GN=H1-3 PE=1 SV=2"	"28"	"8"	"14"	"1"	"221"	"22.3"	"11.02"	"3215.66"	"14.36"	"8"	"4"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00538"	"3007"	"ENSG00000124575"	"H1-3"	"B2R751; hsa:3007; P16402; Q2M2I2"	"Formation of Senescence-Associated Heterochromatin Foci (SAHF); Apoptosis induced DNA fragmentation"	""	"2"	"7"	"1245.7"	"1292.5"	"4185.6"	"1103.9"	"1024.9"	"829.3"	"4426.0"	"465.3"	"632.2"	"510.7"	"547.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P16403"	"Histone H1.2 OS=Homo sapiens OX=9606 GN=H1-2 PE=1 SV=2"	"29"	"8"	"14"	"1"	"213"	"21.4"	"10.93"	"3186.54"	"14.36"	"8"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00538"	"3006"	"ENSG00000187837"	"H1-2"	"A8K4I2; hsa:3006; P16403"	"Apoptosis induced DNA fragmentation; Formation of Senescence-Associated Heterochromatin Foci (SAHF)"	""	"2"	"0"	"62.2"	"73.1"	"193.1"	"63.7"	"65.1"	"49.2"	"167.0"	"23.3"	"29.9"	"21.3"	"18.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P81605"	"Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2"	"35"	"5"	"8"	"5"	"110"	"11.3"	"6.54"	"907.30"	"14.36"	"3"	"4"	"protein metabolism;stress response;transport;other biological processes"	"non-structural extracellular;other membranes"	"transporter activity;other molecular function"	"Pf15291"	"117159"	"ENSG00000161634"	"DCD"	"A5JHP2; A5JHP3; hsa:117159; P58461; P81605; Q53YJ2"	"Antimicrobial peptides"	""	"1"	"0"	"3387.8"	"1276.4"	"1259.6"	"624.4"	"660.4"	"744.2"	"1555.9"	"520.9"	"795.9"	"597.3"	"552.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBQ5"	"Eukaryotic translation initiation factor 3 subunit K OS=Homo sapiens OX=9606 GN=EIF3K PE=1 SV=1"	"20"	"3"	"7"	"3"	"218"	"25.0"	"4.93"	"1235.45"	"14.36"	"2"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf10075"	"27335"	"ENSG00000178982; ENSG00000282986"	"EIF3K"	"A8K0I9; B7ZAM9; hsa:27335; Q96IQ0; Q9UBQ5; Q9Y6D1"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	""	"6"	"0"	"243.9"	"213.0"	"589.2"	"184.0"	"188.4"	"143.6"	"604.7"	"100.6"	"127.6"	"118.4"	"105.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75521"	"Enoyl-CoA delta isomerase 2, mitochondrial OS=Homo sapiens OX=9606 GN=ECI2 PE=1 SV=4"	"11"	"5"	"7"	"5"	"394"	"43.6"	"9.00"	"1261.11"	"14.35"	"3"	"4"	"other metabolic processes"	"cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00378, Pf00887"	"10455"	"ENSG00000198721"	"ECI2"	"hsa:10455; O75521; Q5JYK5; Q5JYK7; Q7L124; Q8N0X0; Q9BUE9; Q9H0T9; Q9NQH1; Q9NYH7; Q9UN55"	""	""	"0"	"0"	"384.7"	"406.9"	"1254.2"	"380.6"	"380.7"	"260.7"	"1437.6"	"298.7"	"490.3"	"602.6"	"785.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61586"	"Transforming protein RhoA OS=Homo sapiens OX=9606 GN=RHOA PE=1 SV=1"	"19"	"3"	"8"	"3"	"193"	"21.8"	"6.10"	"1378.76"	"14.31"	"3"	"3"	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00071"	"387"	"ENSG00000067560"	"RHOA"	"hsa:387; P06749; P61586; Q53HM4; Q5U024; Q9UDJ0; Q9UEJ4"	"Neutrophil degranulation; RHOC GTPase cycle; RHOA GTPase cycle; G alpha (12/13) signalling events; RHO GTPases Activate Formins; EPHB-mediated forward signaling; GPVI-mediated activation cascade; PI3K/AKT activation; VEGFA-VEGFR2 Pathway; ERBB2 Regulates Cell Motility; RHO GTPases activate CIT; G beta:gamma signalling through PI3Kgamma; PCP/CE pathway; RHO GTPases Activate Rhotekin and Rhophilins; EPHA-mediated growth cone collapse; Sema4D induced cell migration and growth-cone collapse; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; Sema4D mediated inhibition of cell attachment and migration; Ovarian tumor domain proteases; SLIT2:ROBO1 increases RHOA activity; PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases; TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition); Axonal growth stimulation; Axonal growth inhibition (RHOA activation); RHO GTPases activate KTN1"	"Androgen receptor signaling pathway; Physiological and pathological hypertrophy of the heart; MicroRNAs in cardiomyocyte hypertrophy; Leptin signaling pathway; Pathogenic Escherichia coli infection; AGE/RAGE pathway; Corticotropin-releasing hormone signaling pathway; Spinal cord injury; Alpha 6 beta 4 signaling pathway; Focal adhesion; G protein signaling pathways; Wnt signaling pathway; Hypothetical craniofacial development pathway; Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; Wnt signaling pathway and pluripotency; Fibrin complement receptor 3 signaling pathway; Wnt signaling in kidney disease; Chromosomal and microsatellite instability in colorectal cancer ; Ebola virus infection in host; Ras signaling; Pancreatic adenocarcinoma pathway; Wnt signaling; Envelope proteins and their potential roles in EDMD physiopathology; Hippo signaling regulation pathways; Leukocyte-intrinsic Hippo pathway functions; Neural crest cell migration during development; Neural crest cell migration in cancer; Joubert syndrome; Gastrin signaling pathway; Netrin-UNC5B signaling pathway; mBDNF and proBDNF regulation of GABA neurotransmission; MAP3K1 role in promoting and blocking gonadal determination; Airway smooth muscle cell contraction; RAS and bradykinin pathways in COVID-19; Regulation of actin cytoskeleton; GDNF signaling; PtdIns(4,5)P2 in cytokinesis pathway; 2q11.2 copy number variation syndrome; 2q21.1 copy number variation syndrome; G13 signaling pathway; 8p23.1 copy number variation syndrome; DNA damage response (only ATM dependent); Serotonin HTR1 group and FOS pathway"	"70"	"0"	"183.4"	"214.1"	"933.6"	"215.6"	"223.5"	"158.4"	"1254.1"	"145.0"	"239.0"	"182.3"	"165.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P45974"	"Ubiquitin carboxyl-terminal hydrolase 5 OS=Homo sapiens OX=9606 GN=USP5 PE=1 SV=2"	"10"	"6"	"9"	"6"	"858"	"95.7"	"5.03"	"2214.78"	"14.29"	"5"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle"	"other molecular function"	"Pf00443, Pf00627, Pf02148, Pf17807"	"8078"	"ENSG00000111667"	"USP5"	"D3DUS7; D3DUS8; hsa:8078; P45974; Q96J22"	"Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Ub-specific processing proteases"	"IL-18 signaling pathway"	"3"	"0"	"192.7"	"281.6"	"949.1"	"250.0"	"274.2"	"249.3"	"1169.6"	"171.6"	"273.5"	"213.8"	"188.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WWY3"	"U4/U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2"	"12"	"4"	"6"	"4"	"499"	"55.4"	"5.78"	"709.12"	"14.28"	"2"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01798, Pf09785"	"26121"	"ENSG00000105618; ENSG00000274144; ENSG00000274651; ENSG00000274894; ENSG00000275117; ENSG00000275885; ENSG00000276421; ENSG00000277154; ENSG00000277707; ENSG00000277953"	"PRPF31"	"E7ESA8; F1T0A4; F1T0A5; hsa:26121; Q17RB4; Q8N7F9; Q8WWY3; Q9H271; Q9Y439"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"33.2"	"38.6"	"108.9"	"29.6"	"37.7"	"21.5"	"208.7"	"47.2"	"83.6"	"63.3"	"79.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82650"	"28S ribosomal protein S22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS22 PE=1 SV=1"	"16"	"5"	"11"	"5"	"360"	"41.3"	"7.90"	"2432.70"	"14.23"	"5"	"4"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf10245"	"56945"	"ENSG00000175110"	"MRPS22"	"hsa:56945; P82650; Q9H3I1"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"Primary ovarian insufficiency"	"4"	"0"	"442.1"	"456.2"	"1327.8"	"438.5"	"339.5"	"322.8"	"1218.5"	"190.3"	"267.0"	"218.2"	"256.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15942"	"Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1"	"10"	"4"	"8"	"4"	"572"	"61.2"	"6.67"	"1571.36"	"14.22"	"4"	"4"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00412"	"7791"	"ENSG00000159840; ENSG00000285443"	"ZYX"	"A4D2G6; B4DQX7; hsa:7791; Q15942; Q6I9S4"	""	"Integrin-mediated cell adhesion; Focal adhesion"	"2"	"0"	"197.9"	"254.7"	"730.8"	"239.9"	"230.3"	"203.3"	"882.1"	"181.7"	"258.2"	"205.1"	"214.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96F85"	"CB1 cannabinoid receptor-interacting protein 1 OS=Homo sapiens OX=9606 GN=CNRIP1 PE=1 SV=1"	"35"	"3"	"4"	"3"	"164"	"18.6"	"7.94"	"269.96"	"14.21"	"1"	"3"	"other biological processes"	"plasma membrane;other membranes;other cell component"	"signal transduction activity or receptor binding"	"Pf15043"	"25927"	"ENSG00000119865"	"CNRIP1"	"B2R4D0; hsa:25927; Q49AN4; Q96F85; Q9UFZ0"	""	""	"0"	"0"	"51.2"	"60.6"	"223.3"	"67.8"	"58.1"	"69.0"	"433.3"	"158.5"	"425.4"	"267.6"	"340.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62820"	"Ras-related protein Rab-1A OS=Homo sapiens OX=9606 GN=RAB1A PE=1 SV=3"	"26"	"5"	"10"	"2"	"205"	"22.7"	"6.21"	"2008.18"	"14.20"	"4"	"4"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;other metabolic processes;stress response;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00071"	"5861"	"ENSG00000138069"	"RAB1A"	"hsa:5861; P11476; P62820; Q6FIE7; Q96N61; Q9Y3T2"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport; RAB GEFs exchange GTP for GDP on RABs; RAB geranylgeranylation; COPII-mediated vesicle transport; Golgi Cisternae Pericentriolar Stack Reorganization"	""	"6"	"1"	"103.0"	"108.3"	"561.4"	"103.9"	"91.8"	"64.1"	"702.7"	"53.5"	"85.8"	"59.9"	"61.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WXF1"	"Paraspeckle component 1 OS=Homo sapiens OX=9606 GN=PSPC1 PE=1 SV=1"	"7"	"2"	"4"	"2"	"523"	"58.7"	"6.67"	"390.98"	"14.17"	"1"	"2"	"stress response;other biological processes"	"nucleus;other cell component"	""	"Pf00076, Pf08075"	"55269"	"ENSG00000121390"	"PSPC1"	"hsa:55269; Q5JTQ3; Q8NCZ9; Q8WXE8; Q8WXF1; Q9NV36"	""	""	"0"	"0"	"220.0"	"203.3"	"537.5"	"200.1"	"185.2"	"172.4"	"535.6"	"103.5"	"160.5"	"117.9"	"125.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14444"	"Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2"	"6"	"4"	"6"	"4"	"709"	"78.3"	"5.25"	"713.29"	"14.17"	"2"	"4"	"cell organization and biogenesis;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf12287, Pf18293"	"4076"	"ENSG00000135387"	"CAPRIN1"	"A6NMY7; D3DR06; hsa:4076; Q14444; Q15074; Q6IMN4; Q6IMN7; Q9BV09"	""	""	"0"	"0"	"234.3"	"264.0"	"1159.2"	"261.9"	"223.6"	"176.6"	"1452.1"	"123.1"	"195.6"	"165.5"	"210.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UNF1"	"Melanoma-associated antigen D2 OS=Homo sapiens OX=9606 GN=MAGED2 PE=1 SV=2"	"14"	"5"	"5"	"5"	"606"	"64.9"	"9.32"	"537.07"	"14.12"	"2"	"3"	"transport;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	""	"Pf01454"	"10916"	"ENSG00000102316"	"MAGED2"	"A6NMX0; hsa:10916; O76058; Q5BJF3; Q8NAL6; Q9H218; Q9P0U9; Q9UM52; Q9UNF1"	"Platelet degranulation"	""	"1"	"0"	"205.1"	"227.0"	"954.2"	"187.5"	"165.2"	"126.6"	"844.0"	"89.5"	"125.7"	"108.9"	"99.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15283"	"Ras GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=RASA2 PE=1 SV=3"	"6"	"5"	"9"	"5"	"850"	"96.6"	"7.20"	"1744.25"	"14.09"	"4"	"3"	"signal transduction;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00168, Pf00169, Pf00616, Pf00779"	"5922"	"ENSG00000155903"	"RASA2"	"A8K7K1; G3V0F9; hsa:5922; O00695; Q15283; Q15284; Q92594; Q99577; Q9UEQ2"	"Regulation of RAS by GAPs"	"MAPK signaling pathway; Ebola virus infection in host; Ras signaling; Modulators of TCR signaling and T cell activation"	"5"	"0"	"160.7"	"95.4"	"291.9"	"128.3"	"123.2"	"95.3"	"287.1"	"117.1"	"450.5"	"502.5"	"485.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NVA2"	"Septin-11 OS=Homo sapiens OX=9606 GN=SEPTIN11 PE=1 SV=3"	"7"	"3"	"10"	"2"	"429"	"49.4"	"6.81"	"1714.32"	"14.02"	"3"	"3"	"cell cycle OR cell proliferation"	"cytoskeleton;other cell component"	"other molecular function"	"Pf00735"	"55752"	"ENSG00000138758"	"SEPTIN11"	"B7Z7Z6; E9KL32; hsa:55752; Q4W5G1; Q7L4N1; Q96SP1; Q9NVA2; Q9UFY9"	""	"22q11.2 copy number variation syndrome"	"1"	"0"	"68.6"	"78.7"	"263.4"	"77.4"	"77.4"	"61.3"	"175.5"	"36.2"	"53.6"	"42.1"	"35.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P00918"	"Carbonic anhydrase 2 OS=Homo sapiens OX=9606 GN=CA2 PE=1 SV=2"	"26"	"5"	"9"	"5"	"260"	"29.2"	"7.40"	"1418.45"	"14.02"	"4"	"5"	"transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00194"	"760"	"ENSG00000104267"	"CA2"	"B2R7G8; hsa:760; P00918; Q6FI12; Q96ET9"	"Reversible hydration of carbon dioxide; Erythrocytes take up carbon dioxide and release oxygen; Erythrocytes take up oxygen and release carbon dioxide"	"Proximal tubule transport"	"4"	"0"	"268.9"	"335.1"	"1314.3"	"319.5"	"291.0"	"191.1"	"1478.1"	"161.7"	"253.0"	"195.1"	"167.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14683"	"Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2"	"7"	"7"	"9"	"7"	"1233"	"143.1"	"7.64"	"1491.00"	"14.01"	"5"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02463, Pf06470"	"8243"	"ENSG00000072501"	"SMC1A"	"hsa:8243; O14995; Q14683; Q16351; Q2M228"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Estrogen-dependent gene expression; Meiotic synapsis; SUMOylation of DNA damage response and repair proteins; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"miRNA regulation of DNA damage response; Cell cycle; Retinoblastoma gene in cancer; Constitutive androstane receptor pathway; Nuclear receptors meta-pathway; Pathways affected in adenoid cystic carcinoma; ATM signaling in development and disease ; mRNA processing; Regulation of sister chromatid separation at the metaphase-anaphase transition; Rett syndrome causing genes; CAMKK2 pathway; Cohesin complex - Cornelia de Lange syndrome; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; DNA damage response"	"21"	"0"	"367.9"	"395.1"	"1223.2"	"369.7"	"310.7"	"267.3"	"948.4"	"132.3"	"167.9"	"208.3"	"286.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96C90"	"Protein phosphatase 1 regulatory subunit 14B OS=Homo sapiens OX=9606 GN=PPP1R14B PE=1 SV=3"	"31"	"2"	"4"	"2"	"147"	"15.9"	"4.86"	"339.94"	"13.99"	"1"	"2"	"stress response;other biological processes"	"other cell component"	"enzyme regulator activity"	"Pf05361"	"26472"	"ENSG00000173457"	"PPP1R14B"	"hsa:26472; Q504S7; Q7KZD7; Q96C90"	""	""	"0"	"0"	"41.7"	"54.3"	"251.5"	"61.5"	"59.1"	"48.7"	"392.1"	"38.4"	"54.0"	"28.2"	"15.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95793"	"Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2"	"9"	"4"	"7"	"4"	"577"	"63.1"	"9.44"	"1116.52"	"13.98"	"3"	"4"	"cell organization and biogenesis;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00035, Pf16482"	"6780"	"ENSG00000124214"	"STAU1"	"A8K9Z4; E1P5Y1; E1P608; hsa:6780; O95793; Q5JW29; Q6GTM4; Q9H5B4; Q9H5B5; Q9Y3Q2"	""	""	"0"	"0"	"217.9"	"237.8"	"786.8"	"237.7"	"255.6"	"174.9"	"805.5"	"91.5"	"166.4"	"127.3"	"121.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P20248"	"Cyclin-A2 OS=Homo sapiens OX=9606 GN=CCNA2 PE=1 SV=2"	"12"	"3"	"5"	"3"	"432"	"48.5"	"6.54"	"1038.09"	"13.94"	"2"	"3"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00134, Pf02984, Pf16500"	"890"	"ENSG00000145386"	"CCNA2"	"A8K7B6; hsa:890; P20248; Q2M3U6; Q4W5P4; Q6LER8"	"TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; Regulation of TP53 Degradation; SCF(Skp2)-mediated degradation of p27/p21; Regulation of TP53 Activity through Phosphorylation; G2 Phase; Telomere Extension By Telomerase; Regulation of APC/C activators between G1/S and early anaphase; Senescence-Associated Secretory Phenotype (SASP); Processing of DNA double-strand break ends; DNA Damage/Telomere Stress Induced Senescence; p53-Dependent G1 DNA Damage Response; Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1; Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes"	"AMP-activated protein kinase signaling; Cell cycle; Retinoblastoma gene in cancer; IL-18 signaling pathway"	"24"	"0"	"58.9"	"73.7"	"226.1"	"70.3"	"64.2"	"61.6"	"236.3"	"60.7"	"94.4"	"117.9"	"178.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62304"	"Small nuclear ribonucleoprotein E OS=Homo sapiens OX=9606 GN=SNRPE PE=1 SV=1"	"38"	"3"	"9"	"3"	"92"	"10.8"	"9.44"	"1474.63"	"13.94"	"2"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01423"	"6635"	"ENSG00000182004"	"SNRPE"	"B2R5B9; hsa:6635; P08578; P62304; Q15498; Q5BKT2"	"SARS-CoV-2 modulates host translation machinery; snRNP Assembly; RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"mRNA processing"	"8"	"0"	"196.2"	"230.4"	"797.9"	"231.0"	"186.3"	"155.4"	"817.3"	"115.6"	"140.7"	"120.2"	"137.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15785"	"Mitochondrial import receptor subunit TOM34 OS=Homo sapiens OX=9606 GN=TOMM34 PE=1 SV=2"	"15"	"3"	"6"	"3"	"309"	"34.5"	"8.98"	"1372.04"	"13.92"	"3"	"3"	"cell organization and biogenesis;transport"	"other membranes;cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00515"	"10953"	"ENSG00000025772"	"TOMM34"	"hsa:10953; Q15785; Q53GH9; Q6IBN7; Q9NTZ3"	""	""	"0"	"0"	"99.8"	"97.2"	"447.7"	"103.6"	"84.4"	"60.1"	"484.9"	"42.2"	"82.4"	"68.1"	"63.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31483"	"Nucleolysin TIA-1 isoform p40 OS=Homo sapiens OX=9606 GN=TIA1 PE=1 SV=3"	"13"	"6"	"10"	"4"	"386"	"42.9"	"7.74"	"1598.60"	"13.89"	"5"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"7072"	"ENSG00000116001"	"TIA1"	"hsa:7072; P31483; Q53SS9; Q96B58"	"FGFR2 alternative splicing"	""	"1"	"2"	"278.8"	"422.8"	"1024.1"	"381.1"	"358.0"	"347.7"	"1329.1"	"328.8"	"440.1"	"331.6"	"387.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P00387"	"NADH-cytochrome b5 reductase 3 OS=Homo sapiens OX=9606 GN=CYB5R3 PE=1 SV=3"	"17"	"4"	"8"	"4"	"301"	"34.2"	"7.59"	"1657.88"	"13.86"	"4"	"4"	"other metabolic processes;other biological processes"	"non-structural extracellular;other membranes;cytosol;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00175, Pf00970"	"1727"	"ENSG00000100243"	"CYB5R3"	"B1AHF2; B7Z7L3; hsa:1727; O75675; P00387; Q8TDL8; Q8WTS8; Q9UEN4; Q9UEN5; Q9UL55; Q9UL56"	"Neutrophil degranulation; Phase I - Functionalization of compounds; Vitamin C (ascorbate) metabolism"	"Oxidation by cytochrome P450"	"4"	"0"	"400.1"	"385.2"	"1940.1"	"401.1"	"299.1"	"172.7"	"1182.0"	"101.9"	"196.0"	"132.2"	"165.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75947"	"ATP synthase subunit d, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PD PE=1 SV=3"	"25"	"3"	"4"	"3"	"161"	"18.5"	"5.30"	"408.73"	"13.85"	"1"	"3"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf05873"	"10476"	"ENSG00000167863"	"ATP5PD"	"B2R5L6; hsa:10476; O75947; Q9H3J4"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"Electron transport chain: OXPHOS system in mitochondria; Oxidative phosphorylation"	"4"	"0"	"110.1"	"114.9"	"620.0"	"141.9"	"119.6"	"70.2"	"519.8"	"34.1"	"79.3"	"61.3"	"57.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01082"	"Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2"	"2"	"5"	"10"	"5"	"2364"	"274.4"	"5.57"	"1640.70"	"13.83"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00169, Pf00307, Pf00435"	"6711"	"ENSG00000115306"	"SPTBN1"	"B2RP63; hsa:6711; O60837; Q01082; Q16057; Q53R99; Q59ER3; Q8IX99"	"RHOV GTPase cycle; RHOU GTPase cycle; COPI-mediated anterograde transport; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Nephrin family interactions; RAF/MAP kinase cascade; NCAM signaling for neurite out-growth; Interaction between L1 and Ankyrins; Signaling by FLT3 fusion proteins"	"Sudden infant death syndrome (SIDS) susceptibility pathways"	"11"	"0"	"117.5"	"127.3"	"425.5"	"121.8"	"104.8"	"84.3"	"380.5"	"51.8"	"76.7"	"72.6"	"113.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63151"	"Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R2A PE=1 SV=1"	"9"	"4"	"9"	"4"	"447"	"51.7"	"6.20"	"1379.58"	"13.77"	"3"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity"	""	"5520"	"ENSG00000221914"	"PPP2R2A"	"B2RBU8; B4E1T7; hsa:5520; P50409; P63151; Q00007"	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Cyclin D associated events in G1; Cyclin A/B1/B2 associated events during G2/M transition; Initiation of Nuclear Envelope (NE) Reformation"	"Wnt signaling pathway and pluripotency; PI3K-Akt signaling pathway; Glycogen synthesis and degradation"	"7"	"0"	"144.3"	"190.2"	"601.0"	"212.4"	"188.0"	"156.8"	"721.4"	"113.9"	"165.0"	"125.6"	"132.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13620"	"Cullin-4B OS=Homo sapiens OX=9606 GN=CUL4B PE=1 SV=4"	"6"	"5"	"10"	"2"	"913"	"103.9"	"7.37"	"1701.43"	"13.74"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00888, Pf10557"	"8450"	"ENSG00000158290"	"CUL4B"	"B1APK5; B3KVX4; B7Z5K8; hsa:8450; Q13620; Q6PIE4; Q6UP07; Q7Z673; Q9BY37; Q9UEB7; Q9UED7"	"Formation of Incision Complex in GG-NER; DNA Damage Recognition in GG-NER; Neddylation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Recognition of DNA damage by PCNA-containing replication complex; Dual Incision in GG-NER"	"Mesodermal commitment pathway; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"13"	"2"	"152.2"	"169.1"	"662.0"	"174.7"	"121.0"	"115.8"	"609.3"	"67.9"	"124.5"	"110.9"	"168.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14739"	"Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2"	"11"	"6"	"11"	"6"	"615"	"70.7"	"9.36"	"1962.34"	"13.71"	"6"	"5"	"other metabolic processes;other biological processes"	"other membranes;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01222, Pf09465"	"3930"	"ENSG00000143815"	"LBR"	"B2R5P3; hsa:3930; Q14739; Q14740; Q53GU7; Q59FE6"	"RHOC GTPase cycle; RHOA GTPase cycle; RHOD GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; Regulation of MECP2 expression and activity; Initiation of Nuclear Envelope (NE) Reformation; Cholesterol biosynthesis"	"Gastric cancer network 2; ATM signaling in development and disease ; Envelope proteins and their potential roles in EDMD physiopathology; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Cholesterol biosynthesis with skeletal dysplasias; Cholesterol synthesis disorders; Cholesterol metabolism; Enterocyte cholesterol metabolism"	"19"	"0"	"380.0"	"401.1"	"1653.9"	"381.5"	"346.2"	"244.8"	"2043.3"	"176.5"	"335.8"	"217.9"	"209.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08237"	"ATP-dependent 6-phosphofructokinase, muscle type OS=Homo sapiens OX=9606 GN=PFKM PE=1 SV=2"	"7"	"5"	"9"	"3"	"780"	"85.1"	"7.99"	"1661.83"	"13.71"	"5"	"4"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus"	"kinase activity;other molecular function"	"Pf00365"	"5213"	"ENSG00000152556"	"PFKM"	"hsa:5213; J3KNX3; P08237; Q16814; Q16815; Q6ZTT1"	"Glycolysis"	"Clear cell renal cell carcinoma pathways; Aerobic glycolysis; Insulin signaling; Glycolysis and gluconeogenesis"	"5"	"2"	"145.6"	"144.2"	"620.1"	"145.7"	"134.2"	"108.1"	"582.5"	"70.5"	"88.0"	"124.9"	"81.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60866"	"40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1"	"34"	"5"	"11"	"5"	"119"	"13.4"	"9.94"	"2421.84"	"13.70"	"5"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00338"	"6224"	"ENSG00000008988"	"RPS20"	"B2R4F4; B4DW28; hsa:6224; P17075; P60866; Q5M8S9"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"681.9"	"726.7"	"2200.8"	"545.4"	"622.3"	"527.8"	"3222.8"	"300.1"	"460.4"	"373.8"	"316.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62847"	"40S ribosomal protein S24 OS=Homo sapiens OX=9606 GN=RPS24 PE=1 SV=1"	"25"	"4"	"9"	"4"	"133"	"15.4"	"10.78"	"1965.74"	"13.69"	"4"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01282"	"6229"	"ENSG00000138326"	"RPS24"	"E7EPK6; hsa:6229; P16632; P62847; Q5T0P7; Q5T0P8; Q7Z3D1"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"631.6"	"718.7"	"2227.5"	"568.0"	"511.0"	"452.2"	"2388.1"	"205.9"	"318.0"	"224.1"	"220.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52907"	"F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3"	"17"	"3"	"6"	"3"	"286"	"32.9"	"5.69"	"1419.77"	"13.68"	"3"	"3"	"cell organization and biogenesis"	"non-structural extracellular;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf01267"	"829"	"ENSG00000116489"	"CAPZA1"	"hsa:829; P52907; Q53FQ6; Q6FHD5"	"MHC class II antigen presentation; COPI-mediated anterograde transport; Sensory processing of sound by inner hair cells of the cochlea; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-independent Golgi-to-ER retrograde traffic; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Factors involved in megakaryocyte development and platelet production; Advanced glycosylation endproduct receptor signaling"	""	"8"	"0"	"64.1"	"72.9"	"235.4"	"64.3"	"54.3"	"49.2"	"254.7"	"40.4"	"62.1"	"46.3"	"53.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16795"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFA9 PE=1 SV=2"	"12"	"3"	"6"	"3"	"377"	"42.5"	"9.80"	"1611.16"	"13.66"	"3"	"3"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf01370"	"4704"	"ENSG00000139180"	"NDUFA9"	"hsa:4704; Q14076; Q16795; Q2NKX0"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Ciliary landscape; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"6"	"0"	"204.2"	"213.4"	"847.5"	"215.3"	"189.5"	"149.2"	"807.8"	"61.1"	"135.6"	"92.6"	"105.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UHD8"	"Septin-9 OS=Homo sapiens OX=9606 GN=SEPTIN9 PE=1 SV=2"	"8"	"4"	"7"	"4"	"586"	"65.4"	"8.97"	"1286.81"	"13.64"	"3"	"4"	"cell cycle OR cell proliferation;other biological processes"	"cytoskeleton;other cell component"	"other molecular function"	"Pf00735"	"10801"	"ENSG00000184640"	"SEPTIN9"	"A8K2V3; B3KPM0; B4DTL9; B4E0N2; B4E274; B7Z654; hsa:10801; Q96QF3; Q96QF4; Q96QF5; Q9HA04; Q9UG40; Q9UHD8; Q9Y5W4"	""	""	"0"	"0"	"390.8"	"350.5"	"1041.0"	"333.8"	"327.1"	"271.3"	"639.4"	"149.2"	"262.6"	"238.0"	"235.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99615"	"DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2"	"8"	"4"	"11"	"4"	"494"	"56.4"	"6.96"	"1864.25"	"13.61"	"4"	"4"	"other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00226, Pf13181, Pf13414, Pf13432"	"7266"	"ENSG00000168259"	"DNAJC7"	"hsa:7266; Q7Z784; Q99615"	"Regulation of HSF1-mediated heat shock response"	"Constitutive androstane receptor pathway; Pregnane X receptor pathway; Nuclear receptors meta-pathway"	"4"	"0"	"249.4"	"291.5"	"1236.1"	"290.4"	"221.1"	"157.8"	"1068.8"	"184.8"	"235.7"	"242.2"	"300.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92665"	"28S ribosomal protein S31, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS31 PE=1 SV=3"	"12"	"4"	"7"	"4"	"395"	"45.3"	"9.29"	"956.86"	"13.60"	"3"	"4"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf15433"	"10240"	"ENSG00000102738"	"MRPS31"	"B2RCS3; hsa:10240; Q5VYC8; Q8WTV8; Q92665"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"277.6"	"323.6"	"769.0"	"285.9"	"268.8"	"255.0"	"1090.0"	"244.7"	"431.3"	"402.2"	"558.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y281"	"Cofilin-2 OS=Homo sapiens OX=9606 GN=CFL2 PE=1 SV=1"	"31"	"6"	"13"	"1"	"166"	"18.7"	"7.88"	"3249.90"	"13.58"	"6"	"4"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf00241"	"1073"	"ENSG00000165410"	"CFL2"	"G3V5P4; hsa:1073; Q9Y281"	""	"Leptin signaling pathway; Microtubule cytoskeleton regulation; Regulation of actin cytoskeleton; G13 signaling pathway"	"4"	"0"	"56.1"	"61.7"	"286.2"	"68.9"	"58.6"	"35.4"	"413.6"	"35.2"	"52.9"	"33.8"	"32.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14802"	"DNA-directed RNA polymerase III subunit RPC1 OS=Homo sapiens OX=9606 GN=POLR3A PE=1 SV=2"	"4"	"4"	"8"	"4"	"1390"	"155.5"	"8.48"	"1358.18"	"13.58"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00623, Pf04983, Pf04997, Pf04998, Pf05000"	"11128"	"ENSG00000148606"	"POLR3A"	"hsa:11128; O14802; Q8IW34; Q8TCW5"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation"	"Pyrimidine metabolism; Cytosolic DNA-sensing pathway"	"9"	"0"	"135.5"	"129.4"	"421.0"	"122.9"	"118.1"	"98.2"	"438.8"	"72.0"	"92.1"	"96.3"	"79.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q02978"	"Mitochondrial 2-oxoglutarate/malate carrier protein OS=Homo sapiens OX=9606 GN=SLC25A11 PE=1 SV=3"	"13"	"3"	"7"	"3"	"314"	"34.0"	"9.91"	"1142.81"	"13.56"	"3"	"3"	"other metabolic processes;transport"	"plasma membrane;other membranes;mitochondrion"	"transporter activity"	"Pf00153"	"8402"	"ENSG00000108528"	"SLC25A11"	"F5GY65; hsa:8402; O75537; Q02978; Q969P7"	"Gluconeogenesis"	"VEGFA-VEGFR2 signaling"	"2"	"0"	"318.9"	"231.8"	"813.2"	"337.8"	"345.3"	"296.1"	"733.4"	"102.8"	"219.9"	"163.1"	"162.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P20962"	"Parathymosin OS=Homo sapiens OX=9606 GN=PTMS PE=1 SV=2"	"24"	"3"	"10"	"3"	"102"	"11.5"	"4.16"	"1858.75"	"13.55"	"3"	"3"	"DNA metabolism;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf03247"	"5763"	"ENSG00000159335"	"PTMS"	"hsa:5763; P20962"	""	"IL-18 signaling pathway"	"1"	"0"	"232.1"	"266.3"	"990.7"	"237.5"	"217.4"	"146.4"	"1375.2"	"155.7"	"167.0"	"118.7"	"85.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EY7"	"Pentatricopeptide repeat domain-containing protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=PTCD3 PE=1 SV=3"	"9"	"4"	"8"	"4"	"689"	"78.5"	"6.42"	"1693.44"	"13.45"	"4"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;translational apparatus;nucleus"	"translation activity;nucleic acid binding activity"	"Pf13041, Pf13812"	"55037"	"ENSG00000132300"	"PTCD3"	"A6NHD2; D6W5M1; hsa:55037; Q597H0; Q658Y9; Q96EY7; Q9BUZ8; Q9NWL0"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"142.3"	"172.9"	"515.6"	"171.0"	"157.1"	"137.5"	"590.2"	"98.9"	"134.0"	"122.0"	"122.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9C005"	"Protein dpy-30 homolog OS=Homo sapiens OX=9606 GN=DPY30 PE=1 SV=1"	"16"	"1"	"6"	"1"	"99"	"11.2"	"4.88"	"1464.36"	"13.44"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport"	"ER/Golgi;nucleus"	"other molecular function"	"Pf05186"	"84661"	"ENSG00000162961"	"DPY30"	"D6W578; hsa:84661; Q9C005"	"Activation of anterior HOX genes in hindbrain development during early embryogenesis; PKMTs methylate histone lysines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Formation of WDR5-containing histone-modifying complexes"	"Kleefstra syndrome"	"5"	"0"	"63.6"	"72.9"	"242.2"	"64.7"	"62.8"	"53.4"	"230.0"	"43.3"	"57.5"	"46.5"	"38.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00505"	"Importin subunit alpha-4 OS=Homo sapiens OX=9606 GN=KPNA3 PE=1 SV=2"	"11"	"4"	"6"	"4"	"521"	"57.8"	"4.94"	"968.98"	"13.42"	"2"	"4"	"cell organization and biogenesis;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00514, Pf01749, Pf16186"	"3839"	"ENSG00000102753"	"KPNA3"	"hsa:3839; O00191; O00505; O43195; Q5JVM9; Q8IYQ9; Q96AA7"	"ISG15 antiviral mechanism; NS1 Mediated Effects on Host Pathways"	""	"2"	"0"	"156.5"	"191.3"	"743.8"	"236.9"	"208.6"	"199.5"	"801.1"	"105.5"	"185.2"	"153.2"	"131.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13045"	"Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2"	"4"	"4"	"8"	"4"	"1269"	"144.7"	"6.05"	"1401.73"	"13.39"	"4"	"4"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00626, Pf12799, Pf13855"	"2314"	"ENSG00000177731; ENSG00000284571"	"FLII"	"B4DIL0; F5H407; hsa:2314; J3QLG3; Q13045"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"134.6"	"193.5"	"668.1"	"149.3"	"147.1"	"101.9"	"735.4"	"83.5"	"111.2"	"101.1"	"109.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08670"	"Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4"	"14"	"5"	"10"	"5"	"466"	"53.6"	"5.12"	"2300.42"	"13.31"	"5"	"4"	"cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00038, Pf04732"	"7431"	"ENSG00000026025"	"VIM"	"B0YJC2; D3DRU4; hsa:7431; P08670; Q15867; Q15868; Q15869; Q548L2; Q6LER9; Q8N850; Q96ML2; Q9NTM3"	"Aggrephagy; Interleukin-4 and Interleukin-13 signaling; Chaperone Mediated Autophagy; Late endosomal microautophagy; Striated Muscle Contraction; RHOBTB1 GTPase cycle; Caspase-mediated cleavage of cytoskeletal proteins"	"Allograft rejection; Spinal cord injury; Primary focal segmental glomerulosclerosis (FSGS); Mammary gland development pathway - Puberty (Stage 2 of 4); Apoptosis-related network due to altered Notch3 in ovarian cancer; Striated muscle contraction pathway; TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition; Ciliary landscape; Burn wound healing; CCL18 signaling pathway; TROP2 regulatory signaling; CKAP4 signaling pathway map; A network map of Macrophage-stimulating protein (MSP) signaling; T-cell receptor signaling pathway"	"21"	"0"	"226.9"	"238.0"	"606.1"	"218.1"	"240.7"	"223.1"	"495.9"	"101.4"	"149.8"	"144.8"	"153.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y678"	"Coatomer subunit gamma-1 OS=Homo sapiens OX=9606 GN=COPG1 PE=1 SV=1"	"5"	"4"	"9"	"4"	"874"	"97.7"	"5.47"	"1122.43"	"13.30"	"4"	"4"	"transport;other biological processes"	"other membranes;cytosol;ER/Golgi"	"other molecular function"	"Pf01602, Pf08752, Pf16381"	"22820"	"ENSG00000181789"	"COPG1"	"A8K6M8; B3KMF6; hsa:22820; Q54AC4; Q9Y678"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport"	"VEGFA-VEGFR2 signaling"	"3"	"0"	"208.7"	"250.1"	"900.3"	"225.0"	"210.7"	"147.6"	"999.4"	"128.9"	"159.2"	"123.8"	"120.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12874"	"Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1"	"9"	"3"	"6"	"3"	"501"	"58.8"	"5.38"	"1266.34"	"13.26"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf11931, Pf12108, Pf13297, Pf16837"	"10946"	"ENSG00000183431"	"SF3A3"	"D3DPT5; hsa:10946; Q12874; Q15460; Q5VT87"	"mRNA Splicing - Major Pathway"	"Exercise-induced circadian regulation; mRNA processing"	"3"	"0"	"214.4"	"204.9"	"636.1"	"210.5"	"204.6"	"184.4"	"511.2"	"64.1"	"114.4"	"83.0"	"75.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99829"	"Copine-1 OS=Homo sapiens OX=9606 GN=CPNE1 PE=1 SV=1"	"10"	"4"	"8"	"4"	"537"	"59.0"	"5.83"	"1660.89"	"13.17"	"4"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00168, Pf07002"	"8904"	"ENSG00000214078"	"CPNE1"	"E1P5Q4; hsa:8904; Q6IBL3; Q99829; Q9H243; Q9NTZ7"	"Neutrophil degranulation; Glycerophospholipid biosynthesis"	""	"2"	"0"	"92.0"	"111.4"	"502.8"	"94.8"	"86.9"	"65.6"	"540.2"	"54.5"	"75.1"	"62.4"	"49.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75962"	"Triple functional domain protein OS=Homo sapiens OX=9606 GN=TRIO PE=1 SV=2"	"2"	"3"	"4"	"3"	"3097"	"346.7"	"6.37"	"350.01"	"13.14"	"1"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00018, Pf00069, Pf00169, Pf00435, Pf00621, Pf00650, Pf07679, Pf16609"	"7204"	"ENSG00000038382"	"TRIO"	"D3DTD1; hsa:7204; O75962; Q13458; Q59EQ7; Q6PJC9; Q6ZN05; Q8IWK8"	"RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; NRAGE signals death through JNK; G alpha (12/13) signalling events; RHOG GTPase cycle; G alpha (q) signalling events; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOJ GTPase cycle; DCC mediated attractive signaling"	"Microtubule cytoskeleton regulation; Neural crest cell migration during development; Neural crest cell migration in cancer"	"14"	"0"	"18.2"	"18.8"	"67.0"	"18.2"	"9.8"	"9.4"	"81.8"	"43.3"	"108.8"	"154.6"	"151.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P80303"	"Nucleobindin-2 OS=Homo sapiens OX=9606 GN=NUCB2 PE=1 SV=3"	"12"	"3"	"5"	"3"	"420"	"50.2"	"5.12"	"754.98"	"13.14"	"2"	"3"	"signal transduction"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf13499"	"4925"	"ENSG00000070081"	"NUCB2"	"A8K642; D3DQX5; hsa:4925; P80303; Q8NFT5; V9HW75"	""	""	"0"	"0"	"102.5"	"129.9"	"496.3"	"136.1"	"132.5"	"102.4"	"562.4"	"84.3"	"124.4"	"84.2"	"111.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NS86"	"LanC-like protein 2 OS=Homo sapiens OX=9606 GN=LANCL2 PE=1 SV=1"	"8"	"3"	"5"	"3"	"450"	"50.8"	"7.43"	"733.53"	"13.10"	"2"	"3"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus"	"other molecular function"	"Pf05147"	"55915"	"ENSG00000132434"	"LANCL2"	"B2R8D4; hsa:55915; Q6NSL4; Q8TCQ3; Q9BSR1; Q9NS86"	""	""	"0"	"0"	"41.1"	"51.0"	"126.4"	"50.5"	"47.3"	"35.3"	"153.6"	"40.6"	"157.3"	"300.7"	"424.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5T749"	"Keratinocyte proline-rich protein OS=Homo sapiens OX=9606 GN=KPRP PE=1 SV=1"	"7"	"2"	"3"	"2"	"579"	"64.1"	"8.27"	"505.10"	"13.10"	"1"	"2"	""	"other cell component"	""	""	"448834"	"ENSG00000203786"	"KPRP"	"hsa:448834; Q5T749"	""	""	"0"	"0"	"238.7"	"140.0"	"181.7"	"59.1"	"50.0"	"51.3"	"149.8"	"36.7"	"41.3"	"37.4"	"37.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4Z0"	"U6 snRNA-associated Sm-like protein LSm4 OS=Homo sapiens OX=9606 GN=LSM4 PE=1 SV=1"	"28"	"5"	"9"	"5"	"139"	"15.3"	"9.99"	"1688.04"	"13.09"	"5"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01423"	"25804"	"ENSG00000130520"	"LSM4"	"hsa:25804; Q9Y4Z0"	"mRNA Splicing - Major Pathway; mRNA decay by 5' to 3' exoribonuclease"	"Ciliary landscape"	"3"	"0"	"131.9"	"167.8"	"579.5"	"187.3"	"180.2"	"127.3"	"714.7"	"109.2"	"199.8"	"158.5"	"168.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P36915"	"Guanine nucleotide-binding protein-like 1 OS=Homo sapiens OX=9606 GN=GNL1 PE=1 SV=2"	"9"	"4"	"7"	"4"	"607"	"68.6"	"5.80"	"1439.61"	"13.08"	"4"	"3"	"stress response;signal transduction;other biological processes"	"non-structural extracellular"	"other molecular function"	"Pf01926"	"2794"	"ENSG00000204590; ENSG00000206492; ENSG00000226882; ENSG00000228581; ENSG00000229470; ENSG00000232143; ENSG00000235986"	"GNL1"	"B0S838; hsa:2794; P36915; Q96CT5"	""	""	"0"	"0"	"72.0"	"93.5"	"250.5"	"77.9"	"89.3"	"74.3"	"337.7"	"59.3"	"76.3"	"72.9"	"79.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q08752"	"Peptidyl-prolyl cis-trans isomerase D OS=Homo sapiens OX=9606 GN=PPID PE=1 SV=3"	"15"	"7"	"12"	"6"	"370"	"40.7"	"7.21"	"2394.74"	"13.06"	"7"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00160, Pf13176"	"5481"	"ENSG00000171497"	"PPID"	"B2R9V2; hsa:5481; Q08752"	"ESR-mediated signaling"	"Alzheimer's disease and miRNA effects; NO/cGMP/PKG mediated neuroprotection; Alzheimer's disease"	"4"	"1"	"373.6"	"419.6"	"1517.1"	"404.6"	"342.0"	"294.8"	"1822.5"	"340.9"	"546.1"	"437.8"	"572.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63173"	"60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2"	"50"	"4"	"9"	"3"	"70"	"8.2"	"10.10"	"1434.94"	"13.06"	"4"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01781"	"6169"	"ENSG00000172809"	"RPL38"	"B2R5A8; hsa:6169; P23411; P63173"	"L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Mesodermal commitment pathway; Mesodermal commitment pathway; Cytoplasmic ribosomal proteins"	"16"	"0"	"166.9"	"171.3"	"532.0"	"150.4"	"163.0"	"122.3"	"629.5"	"67.9"	"123.6"	"118.6"	"112.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BWD1"	"Acetyl-CoA acetyltransferase, cytosolic OS=Homo sapiens OX=9606 GN=ACAT2 PE=1 SV=2"	"15"	"4"	"7"	"4"	"397"	"41.3"	"6.92"	"947.47"	"13.03"	"3"	"4"	"other metabolic processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00108, Pf02803"	"39"	"ENSG00000120437"	"ACAT2"	"B7Z233; E1P5B1; hsa:39; Q16146; Q5TCL7; Q8TDM4; Q9BWD1"	"Cholesterol biosynthesis"	"Mevalonate pathway; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Cholesterol metabolism; Cholesterol biosynthesis pathway in hepatocytes; Enterocyte cholesterol metabolism"	"6"	"0"	"66.6"	"70.4"	"304.4"	"66.8"	"58.8"	"42.4"	"415.1"	"52.4"	"45.6"	"61.5"	"31.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86XP3"	"ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1"	"6"	"4"	"6"	"4"	"938"	"102.9"	"7.02"	"1432.30"	"13.03"	"3"	"3"	"other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"11325"	"ENSG00000198231"	"DDX42"	"A6NML1; A8KA43; hsa:11325; O75619; Q68G51; Q86XP3; Q96BK1; Q96HR7; Q9Y3V8"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	""	"2"	"0"	"258.5"	"321.5"	"683.3"	"283.0"	"305.0"	"248.7"	"709.6"	"161.2"	"222.9"	"183.4"	"210.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19388"	"DNA-directed RNA polymerases I, II, and III subunit RPABC1 OS=Homo sapiens OX=9606 GN=POLR2E PE=1 SV=4"	"29"	"4"	"5"	"4"	"210"	"24.5"	"5.95"	"297.50"	"13.00"	"1"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01191, Pf03871"	"5434"	"ENSG00000099817"	"POLR2E"	"B2R6L4; D6W5Y1; hsa:5434; O43380; P19388; Q6PIH5; Q9BT06"	"mRNA Splicing - Major Pathway; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Transcriptional regulation by small RNAs; B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; RNA Polymerase I Promoter Escape; Inhibition of DNA recombination at telomere; RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; Viral Messenger RNA Synthesis; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Transcription Termination; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM"	"Pyrimidine metabolism; Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"57"	"0"	"147.8"	"158.8"	"448.7"	"166.5"	"155.1"	"131.5"	"582.5"	"139.5"	"348.6"	"329.6"	"314.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51398"	"28S ribosomal protein S29, mitochondrial OS=Homo sapiens OX=9606 GN=DAP3 PE=1 SV=1"	"9"	"3"	"6"	"3"	"398"	"45.5"	"8.88"	"1261.97"	"12.98"	"3"	"3"	"protein metabolism;other metabolic processes;signal transduction"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf10236"	"7818"	"ENSG00000132676"	"DAP3"	"B4DP59; B4DY62; E7EM60; hsa:7818; P51398; Q13044; Q68CT7; Q96Q20"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"CKAP4 signaling pathway map"	"4"	"0"	"273.1"	"232.8"	"759.7"	"318.8"	"262.6"	"249.3"	"872.9"	"137.8"	"225.7"	"188.2"	"145.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P45973"	"Chromobox protein homolog 5 OS=Homo sapiens OX=9606 GN=CBX5 PE=1 SV=1"	"24"	"4"	"8"	"3"	"191"	"22.2"	"5.86"	"1754.91"	"12.96"	"4"	"4"	"cell organization and biogenesis;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00385, Pf01393"	"23468"	"ENSG00000094916"	"CBX5"	"B2R8T9; hsa:23468; P45973"	"SUMOylation of chromatin organization proteins; Transcriptional Regulation by E2F6; Factors involved in megakaryocyte development and platelet production"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; 22q11.2 copy number variation syndrome"	"5"	"1"	"298.2"	"259.0"	"930.2"	"264.6"	"217.2"	"219.0"	"1367.7"	"177.5"	"200.6"	"153.5"	"200.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HD33"	"39S ribosomal protein L47, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL47 PE=1 SV=2"	"16"	"4"	"9"	"4"	"250"	"29.4"	"10.37"	"1077.12"	"12.95"	"4"	"4"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf06984"	"57129"	"ENSG00000136522"	"MRPL47"	"hsa:57129; Q6XRG1; Q8N5D1; Q9HD33"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"184.2"	"176.2"	"587.3"	"176.1"	"169.7"	"146.6"	"736.8"	"96.7"	"170.8"	"126.9"	"146.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15907"	"Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4"	"28"	"6"	"11"	"6"	"218"	"24.5"	"5.94"	"2197.98"	"12.92"	"6"	"4"	"cell-cell signaling;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00071"	"9230"	"ENSG00000185236"	"RAB11B"	"A5YM50; B2R7I4; B4DMK0; D6W671; hsa:9230; Q15907; Q2YDT2; Q5U0I1; Q6FHR0; Q6FI42; Q8NI07"	"RAB geranylgeranylation; TBC/RABGAPs"	"Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Intracellular trafficking proteins involved in CMT neuropathy"	"4"	"0"	"537.3"	"548.2"	"2306.5"	"509.9"	"450.8"	"357.3"	"2098.5"	"246.4"	"335.7"	"295.2"	"270.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00116"	"Alkyldihydroxyacetonephosphate synthase, peroxisomal OS=Homo sapiens OX=9606 GN=AGPS PE=1 SV=1"	"8"	"3"	"5"	"3"	"658"	"72.9"	"7.34"	"912.79"	"12.91"	"2"	"3"	"other metabolic processes"	"cytosol;other cytoplasmic organelle"	"other molecular function"	"Pf01565, Pf02913"	"8540"	"ENSG00000018510"	"AGPS"	"A5D8U9; hsa:8540; O00116; Q2TU35"	"Plasmalogen biosynthesis; TYSND1 cleaves peroxisomal proteins"	"Triacylglyceride synthesis"	"4"	"0"	"73.2"	"71.8"	"321.3"	"73.4"	"54.9"	"46.9"	"363.1"	"38.5"	"50.0"	"47.3"	"51.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NTK5"	"Obg-like ATPase 1 OS=Homo sapiens OX=9606 GN=OLA1 PE=1 SV=2"	"12"	"5"	"9"	"5"	"396"	"44.7"	"7.81"	"1701.50"	"12.84"	"5"	"4"	"other metabolic processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cell component"	"translation activity;other molecular function"	"Pf01926, Pf06071"	"29789"	"ENSG00000138430"	"OLA1"	"D7EHM2; hsa:29789; Q5BJD7; Q8NCI8; Q96CU1; Q96SV2; Q9NTK5; Q9P1D3; Q9UNY9; Q9Y6G4"	"Platelet degranulation"	""	"1"	"0"	"469.4"	"592.7"	"2000.6"	"610.3"	"509.4"	"385.5"	"1948.2"	"278.8"	"456.7"	"393.0"	"462.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15435"	"Protein phosphatase 1 regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PPP1R7 PE=1 SV=1"	"10"	"3"	"8"	"3"	"360"	"41.5"	"4.91"	"1461.79"	"12.81"	"3"	"3"	"other biological processes"	"other cell component"	"enzyme regulator activity"	"Pf14580"	"5510"	"ENSG00000115685"	"PPP1R7"	"B4DFD4; B5MCY6; hsa:5510; Q15435; Q9UQE5; Q9UQE6; Q9Y6K4"	""	"2q37 copy number variation syndrome"	"1"	"0"	"99.5"	"117.5"	"452.1"	"103.1"	"99.8"	"78.4"	"574.3"	"76.6"	"139.3"	"191.5"	"351.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09110"	"3-ketoacyl-CoA thiolase, peroxisomal OS=Homo sapiens OX=9606 GN=ACAA1 PE=1 SV=2"	"8"	"2"	"6"	"2"	"424"	"44.3"	"8.44"	"1469.35"	"12.78"	"2"	"2"	"other metabolic processes"	"non-structural extracellular;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00108, Pf02803"	"30"	"ENSG00000060971"	"ACAA1"	"G5E935; hsa:30; P09110; Q96CA6"	"Neutrophil degranulation; TYSND1 cleaves peroxisomal proteins; alpha-linolenic acid (ALA) metabolism; Beta-oxidation of very long chain fatty acids"	"PPAR-alpha pathway; Nuclear receptors meta-pathway; Amino acid metabolism; PPAR signaling pathway; Eicosanoid metabolism via cyclooxygenases (COX); Eicosanoid metabolism via lipooxygenases (LOX)"	"11"	"0"	"31.0"	"27.9"	"91.7"	"23.8"	"25.9"	"13.5"	"138.0"	"19.3"	"29.9"	"32.6"	"26.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKY7"	"Protein CDV3 homolog OS=Homo sapiens OX=9606 GN=CDV3 PE=1 SV=1"	"14"	"3"	"6"	"3"	"258"	"27.3"	"6.40"	"1546.91"	"12.74"	"3"	"3"	""	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf15359"	"55573"	"ENSG00000091527"	"CDV3"	"B3KUC2; hsa:55573; Q96IP9; Q9UKY7"	""	""	"0"	"0"	"279.9"	"300.9"	"1676.7"	"356.0"	"319.8"	"190.5"	"2487.5"	"168.3"	"400.1"	"404.3"	"633.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6L8Q7"	"2',5'-phosphodiesterase 12 OS=Homo sapiens OX=9606 GN=PDE12 PE=1 SV=2"	"9"	"4"	"6"	"4"	"609"	"67.3"	"6.57"	"737.25"	"12.74"	"2"	"4"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf03372"	"201626"	"ENSG00000174840"	"PDE12"	"B4DTU8; hsa:201626; Q6L8Q7; Q8IYU3; Q8NDU2; Q8TE78"	"OAS antiviral response"	"Phosphodiesterases in neuronal function"	"2"	"0"	"113.4"	"130.5"	"415.6"	"132.4"	"123.4"	"103.0"	"468.2"	"85.2"	"115.7"	"130.4"	"213.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKX7"	"Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2"	"12"	"4"	"7"	"4"	"468"	"50.1"	"7.06"	"1184.89"	"12.74"	"3"	"4"	"transport"	"other membranes;nucleus"	""	"Pf00638, Pf08911"	"10762"	"ENSG00000093000"	"NUP50"	"B1AHA4; B2RB15; hsa:10762; O75644; Q8N6V5; Q9NPM9; Q9NPR6; Q9P1K5; Q9UKX7"	"SARS-CoV-2 activates/modulates innate and adaptive immune responses; Regulation of HSF1-mediated heat shock response; Rev-mediated nuclear export of HIV RNA; SUMOylation of DNA replication proteins; HCMV Late Events; HCMV Early Events; Transcriptional regulation by small RNAs; Transport of Mature mRNA Derived from an Intronless Transcript; tRNA processing in the nucleus; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA derived from an Intron-Containing Transcript; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"	""	"28"	"0"	"52.7"	"66.9"	"290.0"	"77.8"	"56.0"	"52.6"	"320.2"	"42.6"	"58.2"	"46.7"	"58.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P00403"	"Cytochrome c oxidase subunit 2 OS=Homo sapiens OX=9606 GN=MT-CO2 PE=1 SV=1"	"21"	"3"	"7"	"3"	"227"	"25.5"	"4.82"	"1805.66"	"12.72"	"3"	"2"	"other metabolic processes;stress response;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00116, Pf02790"	"4513"	"ENSG00000198712"	"MT-CO2"	"hsa:4513; P00403; Q37526"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"Electron transport chain: OXPHOS system in mitochondria; Endothelin pathways; EGF/EGFR signaling pathway; Nonalcoholic fatty liver disease; Neuroinflammation; Mitochondrial complex IV assembly; CCL18 signaling pathway"	"10"	"0"	"132.5"	"155.3"	"687.0"	"129.4"	"127.4"	"79.4"	"727.7"	"63.7"	"87.6"	"69.1"	"78.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00764"	"Pyridoxal kinase OS=Homo sapiens OX=9606 GN=PDXK PE=1 SV=1"	"16"	"3"	"5"	"3"	"312"	"35.1"	"6.13"	"903.15"	"12.68"	"2"	"3"	"other metabolic processes"	"non-structural extracellular;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf08543"	"8566"	"ENSG00000160209"	"PDXK"	"hsa:8566; O00764; Q7Z2Y0; Q9BS02"	"Neutrophil degranulation; Vitamins B6 activation to pyridoxal phosphate"	""	"2"	"0"	"63.1"	"66.5"	"206.5"	"54.0"	"62.1"	"43.2"	"242.9"	"44.0"	"68.5"	"45.8"	"50.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61956"	"Small ubiquitin-related modifier 2 OS=Homo sapiens OX=9606 GN=SUMO2 PE=1 SV=3"	"27"	"3"	"8"	"3"	"95"	"10.9"	"5.50"	"1412.30"	"12.67"	"3"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf11976"	"6613"	"ENSG00000188612"	"SUMO2"	"B2R4I2; hsa:6613; P55855; P61956; Q32Q42; Q6IPZ6; Q96HK1"	"SUMOylation of chromatin organization proteins; SUMOylation of intracellular receptors; SUMOylation of DNA damage response and repair proteins; SUMOylation of SUMOylation proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; SUMOylation of transcription cofactors; Processing of DNA double-strand break ends; Vitamin D (calciferol) metabolism; SUMOylation of transcription factors; Formation of Incision Complex in GG-NER; SUMO is conjugated to E1 (UBA2:SAE1); SUMO is transferred from E1 to E2 (UBE2I, UBC9); SUMO is proteolytically processed"	""	"14"	"0"	"269.0"	"300.7"	"1430.0"	"268.5"	"232.0"	"146.5"	"1894.9"	"138.7"	"201.9"	"162.3"	"276.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UQ16"	"Dynamin-3 OS=Homo sapiens OX=9606 GN=DNM3 PE=1 SV=4"	"5"	"4"	"8"	"1"	"869"	"97.7"	"8.35"	"1433.16"	"12.67"	"3"	"3"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytoskeleton;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00169, Pf00350, Pf01031, Pf02212"	"26052"	"ENSG00000197959"	"DNM3"	"A9Z1Y1; hsa:26052; O14982; O95555; Q1MTM8; Q5W129; Q6P2G1; Q9H0P3; Q9H548; Q9NQ68; Q9NQN6; Q9UQ16"	"Clathrin-mediated endocytosis; MHC class II antigen presentation; Recycling pathway of L1; Retrograde neurotrophin signalling; Toll Like Receptor 4 (TLR4) Cascade"	"Synaptic vesicle pathway; Alstrom syndrome"	"7"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09622"	"Dihydrolipoyl dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=DLD PE=1 SV=2"	"12"	"6"	"11"	"6"	"509"	"54.1"	"7.85"	"2215.45"	"12.66"	"6"	"3"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytoskeleton;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf02852, Pf07992"	"1738"	"ENSG00000091140"	"DLD"	"B2R5X0; B4DHG0; B4DT69; hsa:1738; P09622; Q14131; Q14167; Q59EV8; Q8WTS4"	"Lysine catabolism; Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid; Citric acid cycle (TCA cycle); Branched-chain amino acid catabolism; Glycine degradation"	"Fatty acid beta-oxidation; TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Tryptophan metabolism; 7q11.23 copy number variation syndrome; Neuroinflammation and glutamatergic signaling; Glycolysis and gluconeogenesis; 10q11.21q11.23 copy number variation syndrome; TCA cycle (aka Krebs or citric acid cycle)"	"17"	"0"	"786.1"	"973.5"	"2739.1"	"1093.8"	"859.5"	"675.7"	"2964.5"	"610.3"	"962.4"	"751.9"	"819.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9GZT3"	"SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1"	"42"	"4"	"7"	"4"	"109"	"12.3"	"10.24"	"1094.36"	"12.66"	"3"	"4"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;mitochondrion;nucleus;other cell component"	""	"Pf00076"	"81892"	"ENSG00000119705"	"SLIRP"	"hsa:81892; J3KMY7; Q9GZT3"	""	""	"0"	"0"	"305.4"	"278.1"	"834.8"	"245.9"	"252.1"	"173.2"	"987.4"	"145.1"	"200.9"	"185.9"	"182.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UJZ1"	"Stomatin-like protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=STOML2 PE=1 SV=1"	"11"	"4"	"8"	"4"	"356"	"38.5"	"7.39"	"1406.48"	"12.65"	"4"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;mitochondrion"	"signal transduction activity or receptor binding;other molecular function"	"Pf01145, Pf16200"	"30968"	"ENSG00000165283"	"STOML2"	"B4E1K7; D3DRN3; hsa:30968; O60376; Q53G29; Q96FY2; Q9P042; Q9UJZ1"	"Processing of SMDT1"	""	"1"	"0"	"117.6"	"121.6"	"577.4"	"141.9"	"124.1"	"106.3"	"652.6"	"39.8"	"79.0"	"60.2"	"47.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13185"	"Chromobox protein homolog 3 OS=Homo sapiens OX=9606 GN=CBX3 PE=1 SV=4"	"22"	"3"	"6"	"2"	"183"	"20.8"	"5.33"	"1551.07"	"12.63"	"3"	"3"	"cell organization and biogenesis;stress response;other biological processes"	"other membranes;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00385, Pf01393"	"11335"	"ENSG00000122565"	"CBX3"	"hsa:11335; Q13185; Q96CD7; Q99409; Q9BVS3; Q9P0Z6"	"RNA Polymerase I Promoter Escape; Transcriptional Regulation by E2F6; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"	"Exercise-induced circadian regulation; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; NIPBL role in DNA damage - Cornelia de Lange syndrome"	"6"	"0"	"238.7"	"264.6"	"1424.5"	"295.7"	"227.1"	"189.4"	"1899.1"	"140.9"	"228.6"	"148.2"	"117.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NVI1"	"Fanconi anemia group I protein OS=Homo sapiens OX=9606 GN=FANCI PE=1 SV=4"	"4"	"4"	"7"	"4"	"1328"	"149.2"	"6.74"	"1001.35"	"12.60"	"3"	"4"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf14674, Pf14675, Pf14676, Pf14677, Pf14678, Pf14679, Pf14680"	"55215"	"ENSG00000140525"	"FANCI"	"A4ZVE4; A5YMH4; A6NJZ0; hsa:55215; Q96JN1; Q96ST0; Q9BT96; Q9NVI1"	"TP53 Regulates Transcription of DNA Repair Genes; Fanconi Anemia Pathway"	"Gastric cancer network 2; DNA repair pathways, full network"	"4"	"0"	"85.2"	"77.6"	"349.4"	"76.0"	"67.1"	"44.8"	"364.1"	"24.1"	"46.5"	"25.1"	"20.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q02413"	"Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2"	"6"	"4"	"8"	"4"	"1049"	"113.7"	"5.03"	"1620.34"	"12.46"	"4"	"4"	"cell adhesion;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00028, Pf01049"	"1828"	"ENSG00000134760"	"DSG1"	"B7Z845; hsa:1828; Q02413"	"Neutrophil degranulation; Formation of the cornified envelope; RND2 GTPase cycle; RND3 GTPase cycle; Apoptotic cleavage of cell adhesion  proteins"	""	"6"	"0"	"369.4"	"168.1"	"179.0"	"92.2"	"61.1"	"58.8"	"155.3"	"38.9"	"44.8"	"36.3"	"36.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13861"	"cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2"	"16"	"5"	"8"	"5"	"404"	"45.5"	"5.07"	"1339.89"	"12.44"	"4"	"4"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00027, Pf02197"	"5576"	"ENSG00000114302"	"PRKAR2A"	"hsa:5576; P13861; Q16823; Q9BUB1"	"Factors involved in megakaryocyte development and platelet production; GPER1 signaling; FCGR3A-mediated IL10 synthesis; ADORA2B mediated anti-inflammatory cytokines production; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Vasopressin regulates renal water homeostasis via Aquaporins; PKA activation; PKA activation in glucagon signalling; Hedgehog 'off' state; DARPP-32 events; CREB1 phosphorylation through the activation of Adenylate Cyclase; ROBO receptors bind AKAP5"	"Myometrial relaxation and contraction pathways; G protein signaling pathways; Lipid metabolism pathway; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; GDNF signaling; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"20"	"0"	"54.0"	"64.3"	"215.1"	"47.8"	"48.2"	"34.8"	"218.8"	"24.0"	"39.2"	"30.7"	"26.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WVV9"	"Heterogeneous nuclear ribonucleoprotein L-like OS=Homo sapiens OX=9606 GN=HNRNPLL PE=1 SV=1"	"7"	"3"	"7"	"2"	"542"	"60.0"	"7.72"	"967.59"	"12.42"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf11835, Pf13893"	"92906"	"ENSG00000143889"	"HNRNPLL"	"hsa:92906; Q53T80; Q5JB51; Q5JB52; Q659B9; Q8IVH5; Q8IVH6; Q8WVV9; Q96HR5"	""	""	"0"	"0"	"98.3"	"102.4"	"221.9"	"83.6"	"77.3"	"77.8"	"239.8"	"41.0"	"84.0"	"59.4"	"72.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15355"	"Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1"	"8"	"4"	"9"	"4"	"546"	"59.2"	"4.36"	"1734.53"	"12.39"	"4"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf00481"	"5496"	"ENSG00000115241"	"PPM1G"	"hsa:5496; O15355"	""	"VEGFA-VEGFR2 signaling; mRNA processing"	"2"	"0"	"343.0"	"311.9"	"1582.6"	"311.0"	"229.9"	"219.1"	"1567.3"	"152.3"	"279.1"	"193.0"	"202.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00487"	"26S proteasome non-ATPase regulatory subunit 14 OS=Homo sapiens OX=9606 GN=PSMD14 PE=1 SV=1"	"22"	"5"	"8"	"5"	"310"	"34.6"	"6.52"	"1474.13"	"12.31"	"4"	"3"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf01398, Pf13012"	"10213"	"ENSG00000115233"	"PSMD14"	"B3KNW2; hsa:10213; O00176; O00487"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Metalloprotease DUBs"	"Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"64"	"0"	"773.3"	"835.4"	"2710.5"	"732.0"	"595.3"	"559.7"	"2124.3"	"245.1"	"383.1"	"334.1"	"348.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P15311"	"Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4"	"7"	"6"	"11"	"5"	"586"	"69.4"	"6.27"	"1762.07"	"12.31"	"6"	"5"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf00769, Pf09379, Pf09380, Pf20492"	"7430"	"ENSG00000092820"	"EZR"	"E1P5A8; hsa:7430; P15311; P23714; Q4VX75; Q96CU8; Q9NSJ4"	"Recycling pathway of L1; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Netrin-1 signaling"	"Pathogenic Escherichia coli infection; AGE/RAGE pathway; VEGFA-VEGFR2 signaling; 16p11.2 proximal deletion syndrome; CCL18 signaling pathway; Regulation of actin cytoskeleton; GDNF signaling"	"11"	"1"	"587.0"	"609.5"	"2199.6"	"525.1"	"344.4"	"351.5"	"628.8"	"145.5"	"233.3"	"228.2"	"255.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14980"	"Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2"	"3"	"4"	"7"	"4"	"2115"	"238.1"	"5.78"	"1904.35"	"12.31"	"4"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	""	"4926"	"ENSG00000137497"	"NUMA1"	"H0YH75; hsa:4926; Q14980; Q14981; Q9BTE9"	"Recruitment of NuMA to mitotic centrosomes; Mitotic Prophase"	"Ectoderm differentiation; Ectoderm differentiation; 8p23.1 copy number variation syndrome"	"5"	"0"	"77.0"	"83.9"	"241.8"	"72.0"	"69.9"	"49.8"	"334.2"	"48.0"	"67.0"	"43.1"	"37.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15008"	"26S proteasome non-ATPase regulatory subunit 6 OS=Homo sapiens OX=9606 GN=PSMD6 PE=1 SV=1"	"13"	"4"	"7"	"4"	"389"	"45.5"	"5.62"	"1719.06"	"12.25"	"4"	"3"	"protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	""	"Pf01399, Pf10602"	"9861"	"ENSG00000163636"	"PSMD6"	"A8K2E0; E9PHI9; hsa:9861; Q15008; Q6UV22"	"AUF1 (hnRNP D0) binds and destabilizes mRNA; Regulation of expression of SLITs and ROBOs; ABC-family proteins mediated transport; Neutrophil degranulation; Ub-specific processing proteases; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Interleukin-1 signaling; Separation of Sister Chromatids; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"64"	"0"	"362.6"	"363.5"	"1501.6"	"402.8"	"318.5"	"247.6"	"1269.7"	"130.8"	"248.2"	"201.7"	"194.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TDI0"	"Chromodomain-helicase-DNA-binding protein 5 OS=Homo sapiens OX=9606 GN=CHD5 PE=1 SV=1"	"3"	"4"	"5"	"1"	"1954"	"222.9"	"6.15"	"685.67"	"12.24"	"2"	"3"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf00385, Pf00628, Pf06461, Pf06465, Pf08073, Pf08074"	"26038"	"ENSG00000116254"	"CHD5"	"hsa:26038; O75032; Q5TG89; Q7LGH2; Q8TDI0; Q9UFR9"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q86X55"	"Histone-arginine methyltransferase CARM1 OS=Homo sapiens OX=9606 GN=CARM1 PE=1 SV=3"	"7"	"3"	"5"	"3"	"608"	"65.8"	"6.73"	"614.25"	"12.22"	"2"	"3"	"cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06325, Pf11531"	"10498"	"ENSG00000142453"	"CARM1"	"A6NN38; hsa:10498; Q86X55"	"Estrogen-dependent gene expression; RMTs methylate histone arginines; PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; Heme signaling; BMAL1:CLOCK,NPAS2 activates circadian gene expression; Transcriptional activation of mitochondrial biogenesis; Cytoprotection by HMOX1; Activation of gene expression by SREBF (SREBP); TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; RORA activates gene expression"	"Androgen receptor signaling pathway; Nitric oxide metabolism in cystic fibrosis"	"15"	"0"	"128.3"	"209.2"	"555.8"	"243.2"	"217.4"	"238.5"	"475.1"	"80.5"	"138.6"	"109.1"	"100.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04632"	"Calpain small subunit 1 OS=Homo sapiens OX=9606 GN=CAPNS1 PE=1 SV=1"	"25"	"4"	"7"	"4"	"268"	"28.3"	"5.20"	"922.80"	"12.21"	"3"	"4"	"protein metabolism;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	""	"826"	"ENSG00000126247"	"CAPNS1"	"A8K0P1; hsa:826; P04632; Q8WTX3; Q96EW0"	"Formation of the cornified envelope; Degradation of the extracellular matrix; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"	"Integrin-mediated cell adhesion"	"4"	"0"	"119.9"	"101.2"	"412.1"	"105.8"	"95.1"	"79.6"	"399.7"	"71.7"	"148.8"	"194.5"	"225.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P56545"	"C-terminal-binding protein 2 OS=Homo sapiens OX=9606 GN=CTBP2 PE=1 SV=1"	"10"	"4"	"8"	"4"	"445"	"48.9"	"6.95"	"1475.32"	"12.21"	"4"	"4"	"cell-cell signaling;cell organization and biogenesis;RNA metabolism OR transcription;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00389, Pf02826"	"1488"	"ENSG00000175029"	"CTBP2"	"A8K2X5; D3DRF5; hsa:1488; O43449; P56545; Q5SQP7; Q69YI3; Q86SV0; Q8IY44; Q9H2T8"	"Repression of WNT target genes; Signaling by TCF7L2 mutants"	"Neural crest differentiation; Notch signaling; Mesodermal commitment pathway; Wnt signaling pathway and pluripotency; lncRNA in canonical Wnt signaling and colorectal cancer; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Ciliary landscape; Pleural mesothelioma"	"11"	"0"	"286.1"	"379.3"	"1366.8"	"357.3"	"288.3"	"246.7"	"1436.8"	"187.4"	"252.1"	"208.1"	"203.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P20073"	"Annexin A7 OS=Homo sapiens OX=9606 GN=ANXA7 PE=1 SV=3"	"10"	"5"	"7"	"5"	"488"	"52.7"	"5.68"	"676.43"	"12.16"	"2"	"5"	"other metabolic processes;other biological processes"	"other membranes;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00191"	"310"	"ENSG00000138279"	"ANXA7"	"hsa:310; P20073; Q5F2H3; Q5T0M6; Q5T0M7"	""	"11p11.2 copy number variation syndrome"	"1"	"0"	"184.8"	"189.0"	"508.5"	"200.0"	"222.0"	"180.4"	"565.7"	"123.0"	"170.0"	"164.8"	"116.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14527"	"Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2"	"6"	"3"	"5"	"3"	"1009"	"113.9"	"8.60"	"807.64"	"12.16"	"2"	"3"	"cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf08797, Pf13923"	"6596"	"ENSG00000071794"	"HLTF"	"D3DNH3; hsa:6596; Q14527; Q14536; Q16051; Q7KYJ6; Q86YA5; Q92652; Q96KM9"	"E3 ubiquitin ligases ubiquitinate target proteins"	"Retinoblastoma gene in cancer"	"2"	"0"	"29.1"	"29.5"	"91.8"	"24.3"	"25.0"	"25.4"	"90.5"	"16.3"	"12.5"	"18.3"	"14.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P36551"	"Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3"	"10"	"3"	"6"	"3"	"454"	"50.1"	"8.25"	"1536.15"	"12.15"	"3"	"3"	"other metabolic processes;other biological processes"	"other membranes;cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf01218"	"1371"	"ENSG00000080819"	"CPOX"	"A8K275; B4DSD5; hsa:1371; P36551; Q14060; Q53F08; Q8IZ45; Q96AF3"	"Heme biosynthesis"	"Hemesynthesis defects and porphyrias; Heme biosynthesis"	"3"	"0"	"153.3"	"167.6"	"649.1"	"165.7"	"134.2"	"103.5"	"964.1"	"95.9"	"120.7"	"84.5"	"82.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61289"	"Proteasome activator complex subunit 3 OS=Homo sapiens OX=9606 GN=PSME3 PE=1 SV=1"	"24"	"6"	"9"	"6"	"254"	"29.5"	"5.95"	"1727.06"	"12.14"	"5"	"4"	"cell cycle OR cell proliferation;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02251, Pf02252"	"10197"	"ENSG00000131467"	"PSME3"	"A8K9A3; hsa:10197; O35563; P61289; P97373; Q12920; Q13172; Q9BQD9"	"Regulation of expression of SLITs and ROBOs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation"	"60"	"0"	"283.6"	"402.8"	"1943.6"	"390.5"	"336.9"	"265.7"	"2164.9"	"171.2"	"385.7"	"491.3"	"857.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NZZ3"	"Charged multivesicular body protein 5 OS=Homo sapiens OX=9606 GN=CHMP5 PE=1 SV=1"	"13"	"4"	"8"	"4"	"219"	"24.6"	"4.83"	"1269.50"	"12.12"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	""	"Pf03357"	"51510"	"ENSG00000086065"	"CHMP5"	"B2RD95; B4DIR6; hsa:51510; Q5VXW2; Q96AV2; Q9HB68; Q9NYS4; Q9NZZ3; Q9Y323"	"Budding and maturation of HIV virion; Endosomal Sorting Complex Required For Transport (ESCRT)"	"Ferroptosis"	"3"	"0"	"249.4"	"339.6"	"1082.6"	"348.0"	"330.6"	"271.3"	"1341.3"	"183.2"	"257.3"	"224.2"	"257.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62899"	"60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1"	"32"	"4"	"10"	"4"	"125"	"14.5"	"10.54"	"1507.61"	"12.12"	"4"	"4"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01198"	"6160"	"ENSG00000071082"	"RPL31"	"B7Z4K2; D3DVJ4; hsa:6160; P12947; P62899; Q53SQ5; Q6IRZ0; Q6LBJ6"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"633.1"	"679.3"	"1956.7"	"558.8"	"516.0"	"458.9"	"2403.4"	"222.8"	"303.2"	"230.7"	"215.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P36871"	"Phosphoglucomutase-1 OS=Homo sapiens OX=9606 GN=PGM1 PE=1 SV=3"	"7"	"4"	"8"	"4"	"562"	"61.4"	"6.76"	"1501.40"	"12.10"	"4"	"4"	"other metabolic processes"	"non-structural extracellular;cytosol;other cell component"	"other molecular function"	"Pf02878, Pf02879, Pf02880"	"5236"	"ENSG00000079739"	"PGM1"	"B2R5N9; B4DPV0; hsa:5236; P36871; Q16105; Q16106; Q5BKZ9; Q6NW22; Q86U74; Q96J40; Q9NTY4"	"Neutrophil degranulation; Glycogen synthesis; Glycogen breakdown (glycogenolysis); Galactose catabolism; Defective PGM1 causes PGM1-CDG"	"Ectoderm differentiation; Clear cell renal cell carcinoma pathways; Glycogen synthesis and degradation; Opioid receptor pathways; Disorders of galactose metabolism ; Disorders of fructose metabolism; UDP-derived sugars synthesis in fibroblasts; Glucuronidation"	"13"	"0"	"301.8"	"365.6"	"1681.1"	"316.6"	"261.8"	"208.4"	"2245.8"	"193.1"	"238.3"	"193.4"	"173.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3C8"	"Ubiquitin-fold modifier-conjugating enzyme 1 OS=Homo sapiens OX=9606 GN=UFC1 PE=1 SV=3"	"22"	"4"	"8"	"4"	"167"	"19.4"	"7.40"	"1351.75"	"12.10"	"4"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes"	""	"other molecular function"	"Pf08694"	"51506"	"ENSG00000143222"	"UFC1"	"A8K9R1; D3DVF9; hsa:51506; Q549X0; Q5VTX1; Q9BS96; Q9P009; Q9Y3C8"	""	""	"0"	"0"	"111.4"	"133.7"	"665.2"	"134.1"	"141.4"	"113.9"	"874.8"	"82.7"	"122.1"	"84.6"	"83.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P28072"	"Proteasome subunit beta type-6 OS=Homo sapiens OX=9606 GN=PSMB6 PE=1 SV=4"	"9"	"2"	"8"	"2"	"239"	"25.3"	"4.92"	"1440.70"	"12.04"	"2"	"2"	"protein metabolism;other metabolic processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00227"	"5694"	"ENSG00000142507"	"PSMB6"	"hsa:5694; P28072; Q96J55"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"62"	"0"	"336.9"	"326.5"	"1225.5"	"280.3"	"159.7"	"152.9"	"1050.2"	"203.7"	"268.4"	"228.0"	"270.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55786"	"Puromycin-sensitive aminopeptidase OS=Homo sapiens OX=9606 GN=NPEPPS PE=1 SV=2"	"5"	"4"	"8"	"4"	"919"	"103.2"	"5.72"	"1434.39"	"12.04"	"4"	"4"	"protein metabolism;other metabolic processes;stress response"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01433, Pf11838, Pf17900"	"9520"	"ENSG00000141279"	"NPEPPS"	"B7Z463; hsa:9520; P55786; Q6P145; Q9NP16; Q9UEM2"	"Antigen processing: Ubiquitination & Proteasome degradation"	""	"1"	"0"	"236.8"	"289.2"	"921.9"	"232.2"	"253.5"	"200.9"	"1120.7"	"182.3"	"239.9"	"178.6"	"173.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P42677"	"40S ribosomal protein S27 OS=Homo sapiens OX=9606 GN=RPS27 PE=1 SV=3"	"26"	"3"	"8"	"3"	"84"	"9.5"	"9.45"	"1320.67"	"12.02"	"3"	"3"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01667"	"6232"	"ENSG00000177954"	"RPS27"	"hsa:6232; P42677; Q5T4L6"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins; 11p11.2 copy number variation syndrome"	"26"	"0"	"680.4"	"726.8"	"2179.5"	"618.0"	"570.1"	"484.3"	"2064.4"	"251.0"	"370.1"	"271.9"	"282.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60613"	"Selenoprotein F OS=Homo sapiens OX=9606 GN=SELENOF PE=1 SV=4"	"18"	"2"	"6"	"2"	"165"	"18.1"	"5.03"	"1228.10"	"12.02"	"2"	"2"	"cell organization and biogenesis;other biological processes"	"ER/Golgi"	"other molecular function"	"Pf08806"	"9403"	"ENSG00000183291"	"SELENOF"	"A0A0B4J1S4; hsa:9403; O60613; Q4GZG7; Q8WU00; Q9BS64; Q9GZW0; Q9NR01"	""	"Selenium metabolism / selenoproteins; Selenium micronutrient network"	"2"	"0"	"80.2"	"100.6"	"210.5"	"102.5"	"91.8"	"84.9"	"196.0"	"49.8"	"71.6"	"60.7"	"57.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60953"	"Cell division control protein 42 homolog OS=Homo sapiens OX=9606 GN=CDC42 PE=1 SV=2"	"11"	"2"	"6"	"2"	"191"	"21.2"	"6.55"	"1327.43"	"12.01"	"2"	"2"	"cell-cell signaling;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00071"	"998"	"ENSG00000070831"	"CDC42"	"hsa:998; P21181; P25763; P60953; Q7L8R5; Q9UDI2"	"RHO GTPases Activate Formins; MAPK6/MAPK4 signaling; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RHOG GTPase cycle; RHO GTPases Activate WASPs and WAVEs; RHO GTPases activate IQGAPs; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOJ GTPase cycle; RHOV GTPase cycle; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; RHOU GTPase cycle; EPHB-mediated forward signaling; DCC mediated attractive signaling; GPVI-mediated activation cascade; VEGFA-VEGFR2 Pathway; Myogenesis; Factors involved in megakaryocyte development and platelet production; G beta:gamma signalling through CDC42; EGFR downregulation; RHO GTPases activate PAKs; Inactivation of CDC42 and RAC1; CD28 dependent Vav1 pathway; RHO GTPases activate KTN1"	"Androgen receptor signaling pathway; Target of rapamycin signaling; Integrin-mediated cell adhesion; RANKL/RANK signaling pathway; Leptin signaling pathway; Microtubule cytoskeleton regulation; Metastatic brain tumor; Pathogenic Escherichia coli infection; RalA downstream regulated genes; B cell receptor signaling pathway; AGE/RAGE pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Spinal cord injury; Focal adhesion; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Oxidative damage response; p38 MAPK signaling pathway; Ebola virus infection in host; Ras signaling; Pancreatic adenocarcinoma pathway; EGF/EGFR signaling pathway; Nonalcoholic fatty liver disease; Hippo signaling regulation pathways; 22q11.2 copy number variation syndrome; Gastrin signaling pathway; Regulation of actin cytoskeleton; G13 signaling pathway; Genetic causes of porto-sinusoidal vascular disease; T-cell receptor signaling pathway; DNA damage response (only ATM dependent)"	"60"	"0"	"327.7"	"373.8"	"1772.0"	"377.9"	"372.7"	"294.8"	"2105.1"	"182.5"	"328.9"	"310.6"	"347.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q3SY69"	"Mitochondrial 10-formyltetrahydrofolate dehydrogenase OS=Homo sapiens OX=9606 GN=ALDH1L2 PE=1 SV=2"	"7"	"4"	"6"	"4"	"923"	"101.7"	"6.52"	"562.96"	"12.01"	"2"	"4"	"other metabolic processes"	"mitochondrion;nucleus"	"other molecular function"	"Pf00171, Pf00550, Pf00551, Pf02911"	"160428"	"ENSG00000136010"	"ALDH1L2"	"hsa:160428; Q3SY68; Q3SY69; Q68D62; Q6AI55; Q8N922"	"Metabolism of folate and pterines"	""	"1"	"0"	"63.9"	"86.4"	"263.7"	"63.6"	"56.0"	"48.8"	"288.0"	"67.0"	"67.9"	"51.4"	"71.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63167"	"Dynein light chain 1, cytoplasmic OS=Homo sapiens OX=9606 GN=DYNLL1 PE=1 SV=1"	"46"	"3"	"4"	"3"	"89"	"10.4"	"7.40"	"462.39"	"11.99"	"1"	"2"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01221"	"8655"	"ENSG00000088986"	"DYNLL1"	"hsa:8655; P63167; Q15701"	"MHC class II antigen presentation; COPI-mediated anterograde transport; Neutrophil degranulation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-independent Golgi-to-ER retrograde traffic; Aggrephagy; Intraflagellar transport; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Recruitment of NuMA to mitotic centrosomes; RHO GTPases Activate Formins; HCMV Early Events; EML4 and NUDC in mitotic spindle formation; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Macroautophagy; Activation of BIM and translocation to mitochondria"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein; Genes related to primary cilium development (based on CRISPR); 3q29 copy number variation syndrome"	"27"	"0"	"196.5"	"265.8"	"993.8"	"243.3"	"247.3"	"249.4"	"1342.0"	"254.4"	"301.5"	"275.1"	"339.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62861"	"40S ribosomal protein S30 OS=Homo sapiens OX=9606 GN=FAU PE=1 SV=1"	"20"	"4"	"8"	"4"	"59"	"6.6"	"12.15"	"1466.46"	"11.99"	"4"	"4"	"protein metabolism;other metabolic processes;stress response"	"non-structural extracellular;cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf04758"	""	"ENSCHIG00000017446; ENSJHYG00000000624; ENSLLEG00000000574"	"Fau; FAU"	"A0A452F0A8; A0A7L0YXB0; A0A8C5IE60; A0A8C5LQJ8; P0C2F0; P62860; P62863; P62864; P62866; P62867; Q05472; Q5RC12; Q8HYI8; Q920W7; Q95261"	""	""	"0"	"0"	"365.8"	"384.0"	"1037.4"	"319.3"	"349.9"	"304.8"	"1410.5"	"178.7"	"312.3"	"224.4"	"195.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09936"	"Ubiquitin carboxyl-terminal hydrolase isozyme L1 OS=Homo sapiens OX=9606 GN=UCHL1 PE=1 SV=2"	"23"	"5"	"8"	"5"	"223"	"24.8"	"5.48"	"1198.97"	"11.96"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01088"	"7345"	"ENSG00000154277"	"UCHL1"	"hsa:7345; P09936; Q4W5K6; Q71UM0"	"UCH proteinases"	"Proteasome degradation; Parkinson's disease pathway; Hepatitis C and hepatocellular carcinoma"	"4"	"0"	"247.8"	"314.9"	"1620.1"	"335.6"	"261.7"	"210.3"	"2388.3"	"217.9"	"249.5"	"204.2"	"193.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UHR4"	"Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 OS=Homo sapiens OX=9606 GN=BAIAP2L1 PE=1 SV=2"	"10"	"4"	"8"	"4"	"511"	"56.8"	"8.68"	"1426.23"	"11.96"	"4"	"4"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus"	"cytoskeletal activity;other molecular function"	"Pf08397, Pf14604"	"55971"	"ENSG00000006453"	"BAIAP2L1"	"A4D268; hsa:55971; Q75L21; Q75L22; Q96CV4; Q9H5F5; Q9UHR4; Q9Y2M8"	"RHOF GTPase cycle; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle"	""	"4"	"0"	"47.8"	"47.1"	"149.7"	"49.7"	"48.7"	"38.4"	"168.7"	"40.8"	"92.5"	"107.8"	"104.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BTT0"	"Acidic leucine-rich nuclear phosphoprotein 32 family member E OS=Homo sapiens OX=9606 GN=ANP32E PE=1 SV=1"	"12"	"3"	"7"	"3"	"268"	"30.7"	"3.85"	"2017.72"	"11.93"	"3"	"2"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf14580"	"81611"	"ENSG00000143401"	"ANP32E"	"B4E0I6; E9PEA6; hsa:81611; Q5TB18; Q5TB20; Q8N1S4; Q8WWW9; Q9BTT0"	""	""	"0"	"0"	"172.4"	"184.5"	"593.6"	"179.7"	"198.8"	"168.9"	"879.3"	"217.1"	"350.8"	"270.8"	"235.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96H20"	"Vacuolar-sorting protein SNF8 OS=Homo sapiens OX=9606 GN=SNF8 PE=1 SV=1"	"10"	"4"	"7"	"4"	"258"	"28.8"	"6.65"	"954.20"	"11.92"	"3"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf04157"	"11267"	"ENSG00000159210"	"SNF8"	"hsa:11267; Q8IXY3; Q96H20; Q9UN50"	"HCMV Late Events; Endosomal Sorting Complex Required For Transport (ESCRT)"	""	"2"	"0"	"233.7"	"228.5"	"625.6"	"220.0"	"250.5"	"202.7"	"820.9"	"354.7"	"944.9"	"1477.6"	"1879.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P53985"	"Monocarboxylate transporter 1 OS=Homo sapiens OX=9606 GN=SLC16A1 PE=1 SV=3"	"9"	"4"	"7"	"4"	"500"	"53.9"	"8.66"	"959.84"	"11.92"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"transporter activity;other molecular function"	"Pf07690"	"6566"	"ENSG00000155380; ENSG00000281917"	"SLC16A1"	"hsa:6566; P53985; Q49A45; Q5T8R6; Q9NSJ9"	"Basigin interactions; Pyruvate metabolism; Aspirin ADME; Proton-coupled monocarboxylate transport; Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT)"	"Photodynamic therapy-induced HIF-1 survival signaling; Fragile X syndrome; Glucose metabolism in triple-negative breast cancer cells"	"8"	"0"	"250.1"	"244.1"	"808.9"	"214.9"	"226.2"	"158.7"	"763.2"	"101.2"	"142.5"	"99.3"	"100.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P42766"	"60S ribosomal protein L35 OS=Homo sapiens OX=9606 GN=RPL35 PE=1 SV=2"	"38"	"6"	"8"	"5"	"123"	"14.5"	"11.05"	"1314.76"	"11.91"	"4"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00831"	"11224"	"ENSG00000136942"	"RPL35"	"A8K4V7; hsa:11224; P42766; Q4VBY5; Q5JTN5; Q6IBC7; Q96QJ7; Q9BYF4"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"485.7"	"526.4"	"1796.5"	"561.5"	"546.5"	"440.7"	"3120.7"	"269.7"	"474.8"	"352.3"	"301.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11413"	"Glucose-6-phosphate 1-dehydrogenase OS=Homo sapiens OX=9606 GN=G6PD PE=1 SV=4"	"8"	"4"	"7"	"4"	"515"	"59.2"	"6.84"	"961.78"	"11.89"	"3"	"4"	"other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00479, Pf02781"	"2539"	"ENSG00000160211"	"G6PD"	"D3DWX9; hsa:2539; P11413; Q16000; Q16765; Q8IU70; Q8IU88; Q8IUA6; Q96PQ2"	"TP53 Regulates Metabolic Genes; NFE2L2 regulates pentose phosphate pathway genes; Pentose phosphate pathway"	"Glutathione metabolism; Pentose phosphate metabolism; Cori cycle; Vitamin D receptor pathway; Nuclear receptors meta-pathway; NRF2 pathway; ATM signaling in development and disease ; Metabolic reprogramming in colon cancer; Vitamin D-sensitive calcium signaling in depression; Pentose phosphate pathway in senescent cells; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Glycolysis in senescence; Sulfation biotransformation reaction"	"16"	"0"	"167.8"	"259.6"	"835.6"	"229.6"	"237.4"	"196.6"	"1208.3"	"151.6"	"229.0"	"208.4"	"246.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52434"	"DNA-directed RNA polymerases I, II, and III subunit RPABC3 OS=Homo sapiens OX=9606 GN=POLR2H PE=1 SV=4"	"21"	"2"	"6"	"2"	"150"	"17.1"	"4.68"	"1509.54"	"11.88"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf03870"	"5437"	"ENSG00000163882"	"POLR2H"	"C9J413; C9JBJ6; C9JCU7; C9JUA8; hsa:5437; P52434; P53802; Q969R0"	"mRNA Splicing - Major Pathway; Estrogen-dependent gene expression; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; B-WICH complex positively regulates rRNA expression; Formation of the Early Elongation Complex; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Abortive elongation of HIV-1 transcript in the absence of Tat; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; mRNA Splicing - Minor Pathway; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"Pyrimidine metabolism; Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"57"	"0"	"57.8"	"61.7"	"184.3"	"55.3"	"62.3"	"51.6"	"239.4"	"73.7"	"176.4"	"159.4"	"185.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09211"	"Glutathione S-transferase P OS=Homo sapiens OX=9606 GN=GSTP1 PE=1 SV=2"	"14"	"2"	"6"	"2"	"210"	"23.3"	"5.64"	"1135.18"	"11.86"	"2"	"2"	"cell cycle OR cell proliferation;other metabolic processes;stress response;developmental processes;other biological processes"	"non-structural extracellular;cytosol;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02798, Pf14497"	"2950"	"ENSG00000084207"	"GSTP1"	"hsa:2950; O00460; P09211; Q15690; Q5TZY3"	"Neutrophil degranulation; Detoxification of Reactive Oxygen Species; Paracetamol ADME; Glutathione conjugation"	"Nuclear receptors meta-pathway; NRF2 pathway; Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling; Exercise-induced circadian regulation; Arachidonate epoxygenase / epoxide hydrolase; Metapathway biotransformation Phase I and II"	"10"	"0"	"130.8"	"168.5"	"962.8"	"167.2"	"178.6"	"117.8"	"1538.0"	"134.4"	"191.7"	"111.6"	"105.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HAV7"	"GrpE protein homolog 1, mitochondrial OS=Homo sapiens OX=9606 GN=GRPEL1 PE=1 SV=2"	"18"	"3"	"6"	"3"	"217"	"24.3"	"8.12"	"1261.81"	"11.86"	"3"	"3"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf01025"	"80273"	"ENSG00000109519"	"GRPEL1"	"B2R783; hsa:80273; Q549M6; Q9HAV7"	"Mitochondrial protein import"	""	"1"	"0"	"203.4"	"250.1"	"1137.8"	"257.6"	"243.8"	"178.8"	"1519.3"	"120.1"	"180.5"	"137.9"	"106.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13011"	"Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial OS=Homo sapiens OX=9606 GN=ECH1 PE=1 SV=2"	"14"	"4"	"7"	"4"	"328"	"35.8"	"8.00"	"1274.70"	"11.84"	"3"	"3"	"other metabolic processes"	"cytosol;mitochondrion;other cytoplasmic organelle"	"other molecular function"	"Pf00378"	"1891"	"ENSG00000104823; ENSG00000282853"	"ECH1"	"A8K745; hsa:1891; Q13011; Q8WVX0; Q96EZ9"	"Peroxisomal protein import"	"Fatty acid biosynthesis; IL-18 signaling pathway"	"3"	"0"	"365.2"	"387.5"	"1082.5"	"408.6"	"358.5"	"284.1"	"1337.5"	"309.8"	"496.5"	"681.4"	"706.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31040"	"Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHA PE=1 SV=2"	"7"	"5"	"9"	"5"	"664"	"72.6"	"7.39"	"1555.87"	"11.83"	"5"	"4"	"other metabolic processes;developmental processes"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf00890, Pf02910"	"6389"	"ENSG00000073578"	"SDHA"	"A8K5J6; B4DJ60; E9PBJ5; hsa:6389; P31040; Q16395; Q59GW8; Q8IW48; Q9UMY5"	"Respiratory electron transport; Citric acid cycle (TCA cycle)"	"Electron transport chain: OXPHOS system in mitochondria; TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Nonalcoholic fatty liver disease; Mitochondrial complex II assembly; Arsenic metabolism and reactive oxygen species generation; TCA cycle (aka Krebs or citric acid cycle)"	"9"	"0"	"607.7"	"725.6"	"2040.2"	"645.0"	"564.2"	"486.4"	"2539.3"	"470.0"	"780.2"	"623.6"	"705.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UNS2"	"COP9 signalosome complex subunit 3 OS=Homo sapiens OX=9606 GN=COPS3 PE=1 SV=3"	"12"	"3"	"6"	"3"	"423"	"47.8"	"6.65"	"1256.83"	"11.78"	"3"	"3"	"protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf01399"	"8533"	"ENSG00000141030"	"COPS3"	"B2R683; B4DY81; hsa:8533; O43191; Q7LDR6; Q9UNS2"	"Neddylation; Cargo recognition for clathrin-mediated endocytosis; Formation of TC-NER Pre-Incision Complex; DNA Damage Recognition in GG-NER"	"Ciliary landscape"	"5"	"0"	"79.4"	"91.3"	"280.4"	"83.6"	"83.6"	"61.2"	"285.4"	"52.2"	"62.3"	"63.3"	"65.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92922"	"SWI/SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3"	"3"	"3"	"8"	"3"	"1105"	"122.8"	"5.76"	"1483.23"	"11.77"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00249, Pf04433, Pf16495, Pf16496, Pf16498"	"6599"	"ENSG00000173473"	"SMARCC1"	"hsa:6599; Q17RS0; Q6P172; Q8IWH2; Q92922"	"RMTs methylate histone arginines; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"	"Androgen receptor network in prostate cancer; Tumor suppressor activity of SMARCB1; Thermogenesis; Kleefstra syndrome"	"6"	"0"	"231.9"	"232.4"	"803.4"	"181.2"	"206.6"	"132.1"	"793.1"	"91.8"	"147.1"	"118.5"	"103.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P17480"	"Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF PE=1 SV=1"	"4"	"3"	"7"	"3"	"764"	"89.4"	"5.81"	"1603.34"	"11.75"	"3"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00505, Pf09011, Pf14887"	"7343"	"ENSG00000108312"	"UBTF"	"A8K6R8; hsa:7343; P17480"	"NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; RNA Polymerase I Promoter Opening"	"Ectoderm differentiation"	"6"	"0"	"119.5"	"104.5"	"358.5"	"93.8"	"85.4"	"66.3"	"406.4"	"63.4"	"111.4"	"163.8"	"225.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y6G9"	"Cytoplasmic dynein 1 light intermediate chain 1 OS=Homo sapiens OX=9606 GN=DYNC1LI1 PE=1 SV=3"	"9"	"4"	"7"	"4"	"523"	"56.5"	"6.42"	"1462.16"	"11.71"	"4"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf05783"	"51143"	"ENSG00000144635"	"DYNC1LI1"	"A2RRG7; hsa:51143; Q53HC8; Q53HK7; Q9Y6G9"	"RHO GTPases Activate Formins; HCMV Early Events; MHC class II antigen presentation; Neutrophil degranulation; COPI-independent Golgi-to-ER retrograde traffic; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-mediated anterograde transport; Aggrephagy; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein"	"15"	"0"	"262.4"	"270.5"	"613.9"	"234.9"	"208.1"	"179.4"	"517.5"	"118.0"	"153.1"	"116.4"	"105.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01085"	"Nucleolysin TIAR OS=Homo sapiens OX=9606 GN=TIAL1 PE=1 SV=1"	"9"	"3"	"6"	"1"	"375"	"41.6"	"7.74"	"1306.98"	"11.67"	"3"	"3"	"cell cycle OR cell proliferation;stress response;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"7073"	"ENSG00000151923"	"TIAL1"	"A8K3T0; A8K4L9; hsa:7073; Q01085"	"FGFR2 alternative splicing"	""	"1"	"0"	"68.4"	"84.6"	"183.2"	"91.0"	"106.2"	"91.0"	"250.9"	"92.4"	"134.8"	"111.8"	"98.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IX12"	"Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2"	"3"	"3"	"6"	"3"	"1150"	"132.7"	"5.76"	"1164.23"	"11.65"	"3"	"3"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02037, Pf14443, Pf14444, Pf19256, Pf19257"	"55749"	"ENSG00000060339"	"CCAR1"	"A0JLT7; A1L4P7; A8K9D4; B4DNP8; B4DRK8; hsa:55749; Q32NE3; Q5EBM3; Q5VUP6; Q6PIZ0; Q6X935; Q8IX12; Q9H8N4; Q9NVA7; Q9NVQ0; Q9NWM6"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"168.5"	"169.4"	"482.7"	"149.6"	"180.7"	"161.8"	"788.0"	"304.3"	"430.6"	"323.3"	"316.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q00325"	"Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=2"	"15"	"6"	"10"	"6"	"362"	"40.1"	"9.38"	"1771.50"	"11.60"	"6"	"4"	"transport"	"plasma membrane;other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00153"	"5250"	"ENSG00000075415"	"SLC25A3"	"B3KS34; hsa:5250; Q00325; Q7Z7N7; Q96A03"	""	""	"0"	"0"	"667.5"	"719.6"	"2802.3"	"679.9"	"596.7"	"438.4"	"2719.3"	"230.5"	"371.6"	"290.5"	"262.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00410"	"Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4"	"5"	"5"	"10"	"5"	"1097"	"123.6"	"4.94"	"1978.73"	"11.56"	"5"	"3"	"transport;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02985, Pf18808, Pf18816, Pf18829"	"3843"	"ENSG00000065150"	"IPO5"	"B4DZA0; hsa:3843; O00410; O15257; Q5T578; Q86XC7"	"vRNP Assembly"	""	"1"	"0"	"339.9"	"346.5"	"1505.0"	"333.0"	"264.0"	"194.8"	"1326.1"	"126.2"	"191.8"	"133.4"	"143.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H2U2"	"Inorganic pyrophosphatase 2, mitochondrial OS=Homo sapiens OX=9606 GN=PPA2 PE=1 SV=2"	"13"	"3"	"6"	"3"	"334"	"37.9"	"7.39"	"1479.11"	"11.51"	"3"	"3"	"other metabolic processes;other biological processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf00719"	"27068"	"ENSG00000138777"	"PPA2"	"B4DLP7; F8WDN9; hsa:27068; I6L9B6; Q4W5E9; Q6PG51; Q8TBW0; Q96E55; Q9H0T0; Q9H2U2; Q9NX37; Q9P033; Q9ULX0"	"Mitochondrial tRNA aminoacylation; Pyrophosphate hydrolysis"	""	"2"	"0"	"40.7"	"49.9"	"180.7"	"47.3"	"40.7"	"26.8"	"186.5"	"30.0"	"33.8"	"27.6"	"44.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13573"	"SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1"	"11"	"4"	"6"	"4"	"536"	"61.5"	"9.52"	"1146.50"	"11.49"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus"	"signal transduction activity or receptor binding;other molecular function"	"Pf02731"	"22938"	"ENSG00000100603"	"SNW1"	"A8K8A9; hsa:22938; Q13483; Q13573; Q32N03; Q5D0D6"	"mRNA Splicing - Major Pathway; Formation of paraxial mesoderm; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Pre-NOTCH Transcription and Translation; Downregulation of SMAD2/3:SMAD4 transcriptional activity; NOTCH1 Intracellular Domain Regulates Transcription; Notch-HLH transcription pathway; NOTCH3 Intracellular Domain Regulates Transcription; Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells; NOTCH4 Intracellular Domain Regulates Transcription; RUNX3 regulates NOTCH signaling"	"Novel intracellular components of RIG-I-like receptor pathway; Splicing factor NOVA regulated synaptic proteins; Notch signaling pathway"	"15"	"0"	"165.8"	"209.3"	"612.0"	"204.2"	"207.9"	"181.8"	"727.8"	"126.8"	"189.0"	"155.6"	"168.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82933"	"28S ribosomal protein S9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS9 PE=1 SV=2"	"13"	"4"	"7"	"4"	"396"	"45.8"	"9.51"	"941.42"	"11.49"	"3"	"4"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf00380"	"64965"	"ENSG00000135972"	"MRPS9"	"hsa:64965; P82933; Q6PG40"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"192.4"	"228.5"	"638.5"	"205.4"	"182.2"	"150.2"	"653.2"	"100.2"	"141.4"	"118.6"	"119.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75874"	"Isocitrate dehydrogenase [NADP] cytoplasmic OS=Homo sapiens OX=9606 GN=IDH1 PE=1 SV=2"	"10"	"4"	"8"	"4"	"414"	"46.6"	"7.01"	"1301.45"	"11.46"	"4"	"4"	"other metabolic processes;stress response;developmental processes;other biological processes"	"non-structural extracellular;cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00180"	"3417"	"ENSG00000138413"	"IDH1"	"hsa:3417; O75874; Q567U4; Q6FHQ6; Q7Z3V0; Q93090; Q9NTJ9; Q9UKW8"	"Peroxisomal protein import; Neutrophil degranulation; Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate; NADPH regeneration; NFE2L2 regulating TCA cycle genes"	"Glutathione metabolism; TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism"	"8"	"0"	"171.0"	"207.3"	"1026.7"	"199.1"	"154.2"	"93.6"	"1314.6"	"101.7"	"89.6"	"89.0"	"73.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P21912"	"Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHB PE=1 SV=3"	"21"	"6"	"10"	"6"	"280"	"31.6"	"8.76"	"1886.24"	"11.43"	"6"	"4"	"other metabolic processes"	"plasma membrane;other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf13085, Pf13534"	"6390"	"ENSG00000117118"	"SDHB"	"B2R545; hsa:6390; P21912; Q0QEY7; Q9NQ12"	"Respiratory electron transport; Citric acid cycle (TCA cycle)"	"Electron transport chain: OXPHOS system in mitochondria; Metabolic reprogramming in colon cancer; Nonalcoholic fatty liver disease; Mitochondrial complex II assembly; TCA cycle (aka Krebs or citric acid cycle)"	"7"	"0"	"477.4"	"582.9"	"1972.1"	"553.6"	"497.6"	"422.7"	"2494.0"	"358.6"	"548.8"	"422.0"	"461.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P18206"	"Vinculin OS=Homo sapiens OX=9606 GN=VCL PE=1 SV=4"	"3"	"3"	"8"	"3"	"1134"	"123.7"	"5.66"	"1444.95"	"11.40"	"3"	"3"	"cell adhesion;cell organization and biogenesis;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01044"	"7414"	"ENSG00000035403"	"VCL"	"hsa:7414; P18206; Q16450; Q5SWX2; Q7Z3B8; Q8IXU7"	"Neutrophil degranulation; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Platelet degranulation ; Signaling by BRAF and RAF1 fusions; Signaling by ALK fusions and activated point mutants; Smooth Muscle Contraction; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants"	"Integrin-mediated cell adhesion; Primary focal segmental glomerulosclerosis (FSGS); Focal adhesion; VEGFA-VEGFR2 signaling; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Melanoma; Regulation of actin cytoskeleton"	"18"	"0"	"69.8"	"76.3"	"582.3"	"60.6"	"40.0"	"39.7"	"791.3"	"23.6"	"17.3"	"28.7"	"28.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H9Y6"	"DNA-directed RNA polymerase I subunit RPA2 OS=Homo sapiens OX=9606 GN=POLR1B PE=1 SV=2"	"5"	"5"	"9"	"5"	"1135"	"128.1"	"7.83"	"1487.95"	"11.40"	"5"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00562, Pf04560, Pf04561, Pf04563, Pf04565, Pf06883"	"84172"	"ENSG00000125630"	"POLR1B"	"B7Z6Y7; B7Z823; F5GZX4; F8W898; hsa:84172; Q2TAM4; Q585T5; Q6ZRR2; Q9H9D3; Q9H9Y6"	"B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"Pyrimidine metabolism; Eukaryotic transcription initiation; 2q13 copy number variation syndrome"	"8"	"0"	"44.0"	"61.7"	"171.1"	"45.5"	"56.1"	"37.3"	"164.4"	"74.3"	"314.9"	"295.9"	"328.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P57076"	"Cilia- and flagella-associated protein 298 OS=Homo sapiens OX=9606 GN=CFAP298 PE=1 SV=1"	"17"	"3"	"5"	"3"	"290"	"33.2"	"7.44"	"959.12"	"11.38"	"2"	"3"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	""	"Pf11069"	"56683"	"ENSG00000159079"	"CFAP298"	"hsa:56683; P57076; Q53FH0"	""	"Ciliopathies"	"1"	"0"	"48.3"	"75.8"	"142.1"	"89.3"	"74.3"	"65.1"	"220.4"	"64.9"	"98.7"	"82.9"	"119.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EP5"	"DAZ-associated protein 1 OS=Homo sapiens OX=9606 GN=DAZAP1 PE=1 SV=1"	"10"	"3"	"7"	"3"	"407"	"43.4"	"8.56"	"913.11"	"11.37"	"2"	"3"	"cell cycle OR cell proliferation;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"26528"	"ENSG00000071626"	"DAZAP1"	"hsa:26528; Q96EP5; Q96MJ3; Q9NRR9"	""	""	"0"	"0"	"261.2"	"277.1"	"706.7"	"267.7"	"262.1"	"252.4"	"1011.1"	"283.0"	"368.5"	"291.6"	"328.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14839"	"Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2"	"3"	"5"	"6"	"2"	"1912"	"217.9"	"5.86"	"900.13"	"11.34"	"3"	"3"	"cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf00385, Pf00628, Pf06461, Pf06465, Pf08073, Pf08074"	"1108"	"ENSG00000111642"	"CHD4"	"hsa:1108; Q14839; Q8IXZ5"	"RNA Polymerase I Transcription Initiation; Potential therapeutics for SARS; HDACs deacetylate histones; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of PTEN gene transcription; Regulation of TP53 Activity through Acetylation; NGF-stimulated transcription"	"Rett syndrome causing genes; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"9"	"3"	"170.3"	"176.0"	"745.1"	"166.5"	"187.6"	"134.4"	"776.9"	"94.8"	"118.2"	"146.1"	"99.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00429"	"Dynamin-1-like protein OS=Homo sapiens OX=9606 GN=DNM1L PE=1 SV=2"	"8"	"3"	"5"	"3"	"736"	"81.8"	"6.81"	"766.33"	"11.32"	"2"	"3"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00350, Pf01031, Pf02212"	"10059"	"ENSG00000087470"	"DNM1L"	"A8K4X9; B4DGC9; B4DSU8; G8JLD5; hsa:10059; J3KPI2; O00429; O14541; O60709; Q59GN9; Q7L6B3; Q8TBT7; Q9BWM1; Q9Y5J2"	"Apoptotic execution phase"	"Synaptic vesicle pathway; CAMKK2 pathway; 10q11.21q11.23 copy number variation syndrome"	"4"	"0"	"73.3"	"81.0"	"268.1"	"75.0"	"89.7"	"69.2"	"333.2"	"58.2"	"74.5"	"63.8"	"56.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13126"	"S-methyl-5'-thioadenosine phosphorylase OS=Homo sapiens OX=9606 GN=MTAP PE=1 SV=2"	"13"	"2"	"5"	"2"	"283"	"31.2"	"7.18"	"986.12"	"11.32"	"1"	"2"	"other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf01048"	"4507"	"ENSG00000099810"	"MTAP"	"hsa:4507; I2G7M5; I2G7M6; I2G7M7; I2G7M8; I2G7M9; I2G7N0; Q13126; Q5T3P3; Q9H010"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Methionine salvage pathway"	"Methionine de novo and salvage pathway"	"3"	"0"	"102.6"	"104.2"	"496.8"	"100.5"	"95.7"	"59.6"	"738.9"	"60.4"	"98.7"	"54.7"	"47.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P158"	"Putative ATP-dependent RNA helicase DHX57 OS=Homo sapiens OX=9606 GN=DHX57 PE=1 SV=2"	"4"	"4"	"7"	"3"	"1386"	"155.5"	"7.71"	"1040.38"	"11.31"	"3"	"4"	""	""	"other molecular function"	"Pf00270, Pf00271, Pf04408, Pf05773, Pf07717, Pf18044"	"90957"	"ENSG00000163214"	"DHX57"	"A2RRC7; hsa:90957; Q53SI4; Q6P158; Q6P9G1; Q7Z6H3; Q8NG17; Q96M33"	""	""	"0"	"0"	"49.3"	"51.6"	"143.8"	"40.3"	"47.0"	"30.9"	"131.5"	"20.0"	"33.0"	"31.8"	"29.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95881"	"Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1"	"30"	"5"	"7"	"5"	"172"	"19.2"	"5.40"	"1649.49"	"11.31"	"4"	"3"	"other biological processes"	"ER/Golgi"	"other molecular function"	"Pf13899"	"51060"	"ENSG00000117862"	"TXNDC12"	"B3KQS0; hsa:51060; O95881; Q5T1T4; Q96H50"	""	""	"0"	"0"	"475.7"	"467.2"	"1211.9"	"730.0"	"577.4"	"599.5"	"1324.7"	"289.4"	"530.9"	"412.7"	"409.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15819"	"Ubiquitin-conjugating enzyme E2 variant 2 OS=Homo sapiens OX=9606 GN=UBE2V2 PE=1 SV=4"	"39"	"3"	"4"	"3"	"145"	"16.4"	"8.09"	"394.04"	"11.29"	"1"	"3"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	""	"Pf00179"	"7336"	"ENSG00000169139"	"UBE2V2"	"hsa:7336; Q15819"	"E3 ubiquitin ligases ubiquitinate target proteins; Antigen processing: Ubiquitination & Proteasome degradation; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; Nonhomologous End-Joining (NHEJ); Formation of Incision Complex in GG-NER"	""	"7"	"0"	"38.5"	"46.4"	"283.4"	"43.9"	"49.9"	"30.0"	"363.1"	"20.6"	"30.5"	"20.0"	"22.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N8S7"	"Protein enabled homolog OS=Homo sapiens OX=9606 GN=ENAH PE=1 SV=2"	"11"	"4"	"6"	"4"	"591"	"66.5"	"6.93"	"1010.73"	"11.29"	"3"	"3"	"cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00568, Pf08776"	"55740"	"ENSG00000154380"	"ENAH"	"D0PQI2; hsa:55740; Q502W5; Q5T5M7; Q5VTQ9; Q5VTR0; Q8N8S7; Q9NVF3; Q9UFB8"	"Generation of second messenger molecules; Signaling by ROBO receptors"	"Regulation of actin cytoskeleton"	"3"	"0"	"105.0"	"110.4"	"407.8"	"95.1"	"92.4"	"64.4"	"667.5"	"97.0"	"116.2"	"90.9"	"97.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q1KMD3"	"Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1"	"7"	"3"	"5"	"3"	"747"	"85.1"	"4.91"	"797.62"	"11.28"	"2"	"3"	""	"nucleus;other cell component"	""	"Pf00622, Pf02037, Pf13671"	"221092"	"ENSG00000214753"	"HNRNPUL2"	"hsa:221092; Q1KMD3; Q8N3B3"	""	""	"0"	"0"	"34.3"	"39.8"	"147.3"	"46.1"	"43.9"	"29.1"	"171.7"	"26.2"	"43.3"	"25.9"	"28.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05091"	"Aldehyde dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH2 PE=1 SV=2"	"8"	"4"	"8"	"3"	"517"	"56.3"	"7.05"	"1504.39"	"11.27"	"4"	"4"	"other metabolic processes;other biological processes"	"mitochondrion"	"other molecular function"	"Pf00171"	"217"	"ENSG00000111275"	"ALDH2"	"B4DW54; E7EUE5; hsa:217; P05091; Q03639; Q6IB13; Q6IV71"	"Smooth Muscle Contraction; Ethanol oxidation; Metabolism of serotonin"	"Fatty acid omega-oxidation; Ethanol effects on histone modifications; Tryptophan metabolism; Fluoroacetic acid toxicity"	"7"	"0"	"37.9"	"39.4"	"223.3"	"29.7"	"39.7"	"23.6"	"281.4"	"18.0"	"23.9"	"19.0"	"16.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00186"	"Syntaxin-binding protein 3 OS=Homo sapiens OX=9606 GN=STXBP3 PE=1 SV=2"	"8"	"4"	"8"	"4"	"592"	"67.7"	"7.80"	"1193.22"	"11.20"	"4"	"4"	"cell adhesion;cell-cell signaling;stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00995"	"6814"	"ENSG00000116266"	"STXBP3"	"A8K269; A8K5K7; hsa:6814; O00186; Q53FW1; Q86YJ3; Q9UPD7"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Disinhibition of SNARE formation"	"Insulin signaling"	"3"	"0"	"79.7"	"78.9"	"341.6"	"75.8"	"64.1"	"39.1"	"307.4"	"46.5"	"53.8"	"52.0"	"64.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75396"	"Vesicle-trafficking protein SEC22b OS=Homo sapiens OX=9606 GN=SEC22B PE=1 SV=4"	"30"	"4"	"5"	"4"	"215"	"24.6"	"6.92"	"1103.91"	"11.09"	"3"	"2"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"140.6"	"141.0"	"605.3"	"132.4"	"120.3"	"83.5"	"742.0"	"63.5"	"91.2"	"71.5"	"67.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23193"	"Transcription elongation factor A protein 1 OS=Homo sapiens OX=9606 GN=TCEA1 PE=1 SV=2"	"30"	"9"	"15"	"9"	"301"	"33.9"	"8.38"	"3424.12"	"11.08"	"9"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01096, Pf07500, Pf08711"	"6917"	"ENSG00000187735"	"TCEA1"	"A6NF25; A8K339; hsa:6917; P23193; Q15563; Q6FG87"	"Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	""	"15"	"0"	"116.3"	"106.4"	"377.5"	"121.7"	"124.1"	"88.9"	"520.7"	"119.4"	"252.4"	"373.5"	"614.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P84103"	"Serine/arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1"	"29"	"3"	"5"	"3"	"164"	"19.3"	"11.65"	"949.27"	"11.07"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6428"	"ENSG00000112081"	"SRSF3"	"B4E241; hsa:6428; O08831; P23152; P84103; Q5R3K0"	"mRNA Splicing - Major Pathway; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript"	"mRNA processing"	"6"	"0"	"86.7"	"114.3"	"290.8"	"52.7"	"72.2"	"64.9"	"383.5"	"53.5"	"84.2"	"74.0"	"72.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35659"	"Protein DEK OS=Homo sapiens OX=9606 GN=DEK PE=1 SV=1"	"10"	"3"	"6"	"3"	"375"	"42.6"	"8.56"	"1081.35"	"11.06"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytoskeleton;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf08766"	"7913"	"ENSG00000124795"	"DEK"	"B2R6K6; B4DN37; hsa:7913; P35659; Q5TGV4; Q5TGV5"	"B-WICH complex positively regulates rRNA expression; Transcriptional regulation of granulopoiesis; Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors"	"IL-18 signaling pathway"	"4"	"0"	"286.9"	"265.4"	"786.1"	"226.8"	"193.7"	"185.8"	"410.3"	"70.6"	"113.1"	"101.2"	"180.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14258"	"E3 ubiquitin/ISG15 ligase TRIM25 OS=Homo sapiens OX=9606 GN=TRIM25 PE=1 SV=2"	"5"	"3"	"6"	"3"	"630"	"70.9"	"8.09"	"924.14"	"11.02"	"3"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00622, Pf13445, Pf13765"	"7706"	"ENSG00000121060"	"TRIM25"	"hsa:7706; Q14258"	"SARS-CoV-1 activates/modulates innate immune responses; ISG15 antiviral mechanism; Interferon gamma signaling; SARS-CoV-2 activates/modulates innate and adaptive immune responses; TRAF6 mediated NF-kB activation; NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10; Termination of translesion DNA synthesis; Negative regulators of DDX58/IFIH1 signaling; Ovarian tumor domain proteases; TRAF3-dependent IRF activation pathway; TRAF6 mediated IRF7 activation"	"Novel intracellular components of RIG-I-like receptor pathway; Cytosolic DNA-sensing pathway; SARS-CoV-2 innate immunity evasion and cell-specific immune response; 1p36 copy number variation syndrome"	"16"	"0"	"39.9"	"40.6"	"144.2"	"47.3"	"36.9"	"32.0"	"160.2"	"16.4"	"27.5"	"23.1"	"25.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43598"	"2'-deoxynucleoside 5'-phosphate N-hydrolase 1 OS=Homo sapiens OX=9606 GN=DNPH1 PE=1 SV=1"	"19"	"3"	"7"	"3"	"174"	"19.1"	"5.05"	"1320.31"	"11.00"	"3"	"2"	"other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf05014"	"10591"	"ENSG00000112667"	"DNPH1"	"B2LUJ9; hsa:10591; O43598"	"Purine catabolism"	""	"1"	"0"	"245.5"	"300.9"	"1249.3"	"267.1"	"288.4"	"203.1"	"1632.5"	"212.0"	"251.7"	"206.2"	"200.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P12270"	"Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3"	"3"	"7"	"11"	"7"	"2363"	"267.1"	"5.02"	"2079.06"	"10.98"	"6"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"other membranes;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf07926"	"7175"	"ENSG00000047410"	"TPR"	"hsa:7175; P12270; Q15624; Q15655; Q5SWY0; Q99968"	"Signaling by ALK fusions and activated point mutants; HCMV Late Events; HCMV Early Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses"	""	"29"	"0"	"111.8"	"111.8"	"542.5"	"111.6"	"74.4"	"70.7"	"589.0"	"61.6"	"73.5"	"86.1"	"110.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H2G2"	"STE20-like serine/threonine-protein kinase OS=Homo sapiens OX=9606 GN=SLK PE=1 SV=1"	"4"	"3"	"5"	"3"	"1235"	"142.6"	"5.15"	"664.98"	"10.97"	"2"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf12474"	"9748"	"ENSG00000065613"	"SLK"	"D3DRA0; D3DRA1; hsa:9748; O00211; Q6P1Z4; Q86WU7; Q86WW1; Q92603; Q9H2G2; Q9NQL0; Q9NQL1"	"RHOC GTPase cycle; RHOA GTPase cycle; RHOB GTPase cycle"	""	"3"	"0"	"110.7"	"120.1"	"461.4"	"110.5"	"104.7"	"73.6"	"413.3"	"62.1"	"96.8"	"81.1"	"80.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4W6"	"AFG3-like protein 2 OS=Homo sapiens OX=9606 GN=AFG3L2 PE=1 SV=2"	"5"	"4"	"8"	"4"	"797"	"88.5"	"8.66"	"1383.07"	"10.95"	"4"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf00004, Pf01434, Pf06480, Pf17862"	"10939"	"ENSG00000141385"	"AFG3L2"	"hsa:10939; Q6P1L0; Q9Y4W6"	"Processing of SMDT1"	"Ciliary landscape"	"2"	"0"	"327.0"	"320.3"	"1133.6"	"302.3"	"269.2"	"243.1"	"1040.1"	"98.1"	"188.9"	"151.0"	"131.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08579"	"U2 small nuclear ribonucleoprotein B'' OS=Homo sapiens OX=9606 GN=SNRPB2 PE=1 SV=1"	"12"	"3"	"8"	"2"	"225"	"25.5"	"9.72"	"1153.85"	"10.94"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6629"	"ENSG00000125870"	"SNRPB2"	"B2R7J3; D3DW21; hsa:6629; P08579; Q9UJD4"	"mRNA Splicing - Major Pathway"	"mRNA processing; Ciliary landscape"	"3"	"1"	"576.2"	"529.1"	"1530.0"	"541.7"	"505.8"	"455.9"	"1605.9"	"209.0"	"427.0"	"401.6"	"564.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23381"	"Tryptophan--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=WARS1 PE=1 SV=2"	"9"	"3"	"4"	"3"	"471"	"53.1"	"6.23"	"309.17"	"10.92"	"1"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00458, Pf00579"	"7453"	"ENSG00000140105"	"WARS1"	"A6NGN1; A6NID3; hsa:7453; P23381; P78535; Q502Y0; Q53XB6; Q9UDI5; Q9UDL3"	"Cytosolic tRNA aminoacylation"	"Photodynamic therapy-induced unfolded protein response; Amino acid metabolism"	"3"	"0"	"46.0"	"49.2"	"156.2"	"50.7"	"63.1"	"38.0"	"259.5"	"38.5"	"85.3"	"65.3"	"386.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P41567"	"Eukaryotic translation initiation factor 1 OS=Homo sapiens OX=9606 GN=EIF1 PE=1 SV=1"	"25"	"3"	"6"	"1"	"113"	"12.7"	"7.44"	"1146.74"	"10.81"	"3"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf01253"	"10209"	"ENSG00000173812"	"EIF1"	"hsa:10209; P41567; Q9UNQ9"	""	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"2"	"0"	"12.0"	"14.1"	"10.6"	"4.7"	"4.7"	"4.6"	"32.6"	"15.3"	"25.3"	"29.6"	"84.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11766"	"Alcohol dehydrogenase class-3 OS=Homo sapiens OX=9606 GN=ADH5 PE=1 SV=4"	"11"	"4"	"7"	"4"	"374"	"39.7"	"7.49"	"1372.34"	"10.79"	"4"	"3"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf00107, Pf08240"	"128"	"ENSG00000197894"	"ADH5"	"hsa:128; P11766; Q6FHR2"	"Ethanol oxidation"	"Folate-alcohol and cancer pathway hypotheses; Amino acid metabolism"	"3"	"0"	"283.4"	"341.8"	"1503.0"	"349.1"	"307.3"	"218.6"	"1812.0"	"188.7"	"257.8"	"200.3"	"193.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15424"	"Scaffold attachment factor B1 OS=Homo sapiens OX=9606 GN=SAFB PE=1 SV=4"	"4"	"4"	"9"	"4"	"915"	"102.6"	"5.47"	"1680.03"	"10.79"	"4"	"3"	"cell organization and biogenesis;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf02037"	"6294"	"ENSG00000160633"	"SAFB"	"A0AV56; B7Z5B6; B7ZLP6; F5H0H3; hsa:6294; O60406; Q15424; Q59HH8"	"SUMOylation of transcription cofactors"	"Interleukin-1 (IL-1) structural pathway"	"2"	"0"	"318.3"	"361.6"	"1354.5"	"314.4"	"284.8"	"216.1"	"1692.6"	"207.8"	"286.2"	"214.4"	"188.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60981"	"Destrin OS=Homo sapiens OX=9606 GN=DSTN PE=1 SV=3"	"44"	"6"	"11"	"5"	"165"	"18.5"	"7.85"	"2425.30"	"10.76"	"5"	"3"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf00241"	"11034"	"ENSG00000125868"	"DSTN"	"B2R6N2; B4DYA6; hsa:11034; P18282; P60981; Q5W166; Q6IAW2"	""	"Androgen receptor signaling pathway"	"1"	"0"	"197.0"	"236.4"	"922.3"	"275.5"	"212.1"	"188.0"	"1258.5"	"135.4"	"239.2"	"171.0"	"159.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01780"	"Exosome component 10 OS=Homo sapiens OX=9606 GN=EXOSC10 PE=1 SV=2"	"5"	"3"	"5"	"3"	"885"	"100.8"	"8.46"	"588.88"	"10.75"	"2"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00570, Pf01612, Pf08066"	"5394"	"ENSG00000171824"	"EXOSC10"	"B1AKQ0; B1AKQ1; hsa:5394; Q01780; Q15158"	"Major pathway of rRNA processing in the nucleolus and cytosol"	""	"1"	"0"	"138.4"	"137.1"	"393.4"	"122.2"	"124.9"	"111.2"	"440.2"	"70.2"	"113.0"	"94.3"	"105.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61006"	"Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1"	"14"	"3"	"8"	"1"	"207"	"23.7"	"9.07"	"1305.52"	"10.74"	"3"	"3"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00071"	"4218"	"ENSG00000167461"	"RAB8A"	"B4DEK7; hsa:4218; P24407; P61006; Q6FHV5"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; RAB geranylgeranylation; RAB GEFs exchange GTP for GDP on RABs; Regulation of PLK1 Activity at G2/M Transition; Anchoring of the basal body to the plasma membrane; VxPx cargo-targeting to cilium; TBC/RABGAPs"	"Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Ciliary landscape; Joubert syndrome; 10q11.21q11.23 copy number variation syndrome"	"11"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EK6"	"Glucosamine 6-phosphate N-acetyltransferase OS=Homo sapiens OX=9606 GN=GNPNAT1 PE=1 SV=1"	"22"	"3"	"6"	"3"	"184"	"20.7"	"7.99"	"1056.69"	"10.74"	"3"	"3"	"other metabolic processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle"	"other molecular function"	"Pf00583"	"64841"	"ENSG00000100522"	"GNPNAT1"	"hsa:64841; Q96EK6"	"Synthesis of UDP-N-acetyl-glucosamine"	""	"1"	"0"	"65.0"	"75.5"	"307.3"	"82.3"	"67.5"	"40.6"	"317.4"	"45.7"	"78.9"	"47.7"	"62.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75351"	"Vacuolar protein sorting-associated protein 4B OS=Homo sapiens OX=9606 GN=VPS4B PE=1 SV=2"	"14"	"5"	"9"	"3"	"444"	"49.3"	"7.23"	"1918.27"	"10.73"	"5"	"4"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00004, Pf04212, Pf09336, Pf17862"	"9525"	"ENSG00000119541"	"VPS4B"	"hsa:9525; O75351; Q69HW4; Q9GZS7"	"Budding and maturation of HIV virion; Endosomal Sorting Complex Required For Transport (ESCRT)"	""	"2"	"2"	"97.8"	"119.4"	"465.0"	"97.6"	"83.9"	"52.5"	"585.9"	"59.1"	"65.3"	"57.4"	"52.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NZL9"	"Methionine adenosyltransferase 2 subunit beta OS=Homo sapiens OX=9606 GN=MAT2B PE=1 SV=1"	"7"	"3"	"6"	"3"	"334"	"37.5"	"7.36"	"1260.09"	"10.72"	"3"	"3"	"other metabolic processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf04321"	"27430"	"ENSG00000038274"	"MAT2B"	"B2R5Y6; hsa:27430; Q1WAI7; Q27J92; Q3LIE8; Q567T7; Q6NYC7; Q9BS89; Q9H3E1; Q9NZL9; Q9UJ54"	"Ub-specific processing proteases; Methylation"	"Trans-sulfuration pathway; One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways; Methionine de novo and salvage pathway; Methylation pathways"	"7"	"0"	"172.5"	"232.7"	"683.8"	"176.7"	"185.3"	"137.4"	"849.1"	"149.9"	"173.4"	"125.3"	"107.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBB4"	"Ataxin-10 OS=Homo sapiens OX=9606 GN=ATXN10 PE=1 SV=1"	"7"	"3"	"8"	"3"	"475"	"53.5"	"5.25"	"1424.47"	"10.71"	"3"	"3"	"cell organization and biogenesis;developmental processes"	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf09759"	"25814"	"ENSG00000130638"	"ATXN10"	"A6NLC4; B4DG05; hsa:25814; O14998; O15009; Q6I9X4; Q9UBB4"	""	"Ciliopathies"	"1"	"0"	"256.5"	"300.9"	"1319.7"	"284.9"	"215.2"	"183.2"	"1563.1"	"163.3"	"244.7"	"225.3"	"251.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IZP0"	"Abl interactor 1 OS=Homo sapiens OX=9606 GN=ABI1 PE=1 SV=4"	"7"	"2"	"6"	"2"	"508"	"55.0"	"7.06"	"1612.02"	"10.71"	"2"	"2"	"cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00018, Pf07815"	"10006"	"ENSG00000136754"	"ABI1"	"A9Z1Y6; B3KX62; B4DQ58; H7BXI6; hsa:10006; O15147; O76049; O95060; Q5T2R3; Q5T2R4; Q5T2R6; Q5T2R7; Q5T2R9; Q5W070; Q5W072; Q8IZP0; Q8TB63; Q96S81; Q9NXZ9; Q9NYB8"	"Regulation of actin dynamics for phagocytic cup formation; VEGFA-VEGFR2 Pathway; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs"	"EGF/EGFR signaling pathway"	"8"	"0"	"220.9"	"224.4"	"382.5"	"187.8"	"220.2"	"220.3"	"369.5"	"120.6"	"189.3"	"176.2"	"143.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96FW1"	"Ubiquitin thioesterase OTUB1 OS=Homo sapiens OX=9606 GN=OTUB1 PE=1 SV=2"	"13"	"3"	"5"	"3"	"271"	"31.3"	"4.94"	"637.96"	"10.70"	"2"	"3"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf10275"	"55611"	"ENSG00000167770"	"OTUB1"	"hsa:55611; Q32Q78; Q96FW1; Q96II3; Q9NXQ4; Q9P0B8"	"Ub-specific processing proteases; Ovarian tumor domain proteases"	""	"2"	"0"	"110.7"	"133.0"	"814.4"	"117.5"	"108.4"	"80.4"	"1189.8"	"78.3"	"99.6"	"70.5"	"67.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P47914"	"60S ribosomal protein L29 OS=Homo sapiens OX=9606 GN=RPL29 PE=1 SV=2"	"25"	"5"	"8"	"5"	"159"	"17.7"	"11.66"	"1088.29"	"10.70"	"3"	"4"	"protein metabolism;other metabolic processes;developmental processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01779"	"6159"	"ENSG00000162244"	"RPL29"	"A8K0H3; B2R4M8; hsa:6159; P47914; Q6IPY3"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"958.9"	"1050.2"	"2979.5"	"918.5"	"851.5"	"750.3"	"4067.7"	"386.3"	"561.9"	"413.6"	"354.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O76003"	"Glutaredoxin-3 OS=Homo sapiens OX=9606 GN=GLRX3 PE=1 SV=2"	"12"	"3"	"6"	"3"	"335"	"37.4"	"5.39"	"989.75"	"10.69"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00085, Pf00462"	"10539"	"ENSG00000108010"	"GLRX3"	"B3KMP7; B3KMQ5; D3DRG2; hsa:10539; O76003; Q5JV01; Q96CE0; Q9P1B0; Q9P1B1"	"Iron uptake and transport"	""	"1"	"0"	"208.6"	"199.5"	"703.4"	"185.5"	"198.2"	"171.2"	"726.2"	"114.1"	"159.7"	"123.4"	"105.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11216"	"Glycogen phosphorylase, brain form OS=Homo sapiens OX=9606 GN=PYGB PE=1 SV=5"	"4"	"3"	"8"	"1"	"843"	"96.6"	"6.86"	"1177.07"	"10.68"	"3"	"3"	"other metabolic processes"	"non-structural extracellular;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00343"	"5834"	"ENSG00000100994"	"PYGB"	"hsa:5834; P11216; Q96AK1; Q9NPX8"	"Neutrophil degranulation; Glycogen breakdown (glycogenolysis)"	"IL-18 signaling pathway; Glycogen synthesis and degradation"	"4"	"0"	"13.3"	"14.2"	"76.2"	"13.3"	"15.0"	"12.3"	"108.9"	"9.4"	"10.9"	"8.3"	"6.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86U42"	"Polyadenylate-binding protein 2 OS=Homo sapiens OX=9606 GN=PABPN1 PE=1 SV=3"	"15"	"5"	"8"	"5"	"306"	"32.7"	"5.06"	"1291.74"	"10.66"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;transport;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"8106"	"ENSG00000100836"	"PABPN1"	"D3DS49; hsa:8106; O43484; Q86U42"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs; Inhibition of Host mRNA Processing and RNA Silencing"	"mRNA processing"	"6"	"0"	"348.3"	"429.2"	"1513.5"	"407.0"	"401.9"	"349.2"	"1857.0"	"208.4"	"318.5"	"251.1"	"255.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H307"	"Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5"	"5"	"3"	"6"	"3"	"717"	"81.6"	"7.14"	"1137.61"	"10.64"	"3"	"3"	"cell adhesion;RNA metabolism OR transcription;other metabolic processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04696, Pf04697"	"5411"	"ENSG00000100941"	"PNN"	"B4DZX8; hsa:5411; O60899; Q53EM7; Q6P5X4; Q7KYL1; Q99738; Q9H307; Q9UHZ9; Q9UQR9"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"124.4"	"120.2"	"502.4"	"117.2"	"127.7"	"88.6"	"632.9"	"62.6"	"105.6"	"66.1"	"64.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13148"	"TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1"	"10"	"4"	"8"	"4"	"414"	"44.7"	"6.19"	"1237.01"	"10.63"	"4"	"4"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf18694"	"23435"	"ENSG00000120948"	"TARDBP"	"A4GUK4; A4GUK5; A4GUK6; B2R629; B4DJ45; E2PU12; hsa:23435; Q13148; Q53H27; Q6FI92; Q96DJ0"	""	"MECP2 and associated Rett syndrome"	"1"	"0"	"117.2"	"127.4"	"592.1"	"148.3"	"142.8"	"99.0"	"619.7"	"72.3"	"104.8"	"81.3"	"93.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15286"	"Ras-related protein Rab-35 OS=Homo sapiens OX=9606 GN=RAB35 PE=1 SV=1"	"16"	"3"	"7"	"1"	"201"	"23.0"	"8.29"	"965.84"	"10.61"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00071"	"11021"	"ENSG00000111737"	"RAB35"	"B2R6E0; B4E390; hsa:11021; Q15286"	"RAB GEFs exchange GTP for GDP on RABs; RAB geranylgeranylation; TBC/RABGAPs"	""	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60739"	"Eukaryotic translation initiation factor 1b OS=Homo sapiens OX=9606 GN=EIF1B PE=1 SV=2"	"25"	"3"	"6"	"1"	"113"	"12.8"	"7.37"	"1094.77"	"10.60"	"3"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"translational apparatus"	"translation activity;nucleic acid binding activity"	"Pf01253"	"10289"	"ENSG00000114784"	"EIF1B"	"hsa:10289; O60739; Q9UQF8"	""	""	"0"	"2"	"162.9"	"163.7"	"395.6"	"155.6"	"131.3"	"115.8"	"563.7"	"100.3"	"181.9"	"192.6"	"403.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P36959"	"GMP reductase 1 OS=Homo sapiens OX=9606 GN=GMPR PE=1 SV=1"	"9"	"2"	"5"	"1"	"345"	"37.4"	"7.06"	"690.22"	"10.60"	"1"	"2"	"other metabolic processes;stress response"	"cytosol;other cell component"	"other molecular function"	"Pf00478"	"2766"	"ENSG00000137198"	"GMPR"	"hsa:2766; P36959; Q96HQ6"	"Purine salvage"	""	"1"	"0"	"10.5"	"7.2"	"21.1"	"10.2"	"7.0"	"7.7"	"28.0"	"14.8"	"37.6"	"65.0"	"135.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQ61"	"Telomerase RNA component interacting RNase OS=Homo sapiens OX=9606 GN=TRIR PE=1 SV=1"	"15"	"1"	"2"	"1"	"176"	"18.4"	"9.44"	""	"10.60"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	""	"nucleic acid binding activity;other molecular function"	""	"79002"	"ENSG00000123144"	"TRIR"	"hsa:79002; Q9BQ61"	""	""	"0"	"0"	"27.6"	"22.2"	"57.0"	"26.6"	"26.3"	"17.8"	"85.9"	"15.2"	"32.2"	"18.3"	"25.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61513"	"60S ribosomal protein L37a OS=Homo sapiens OX=9606 GN=RPL37A PE=1 SV=2"	"42"	"3"	"6"	"3"	"92"	"10.3"	"10.43"	"1012.10"	"10.59"	"2"	"2"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01780"	"6168"	"ENSG00000197756"	"RPL37A"	"hsa:6168; P12751; P61513; Q6FGF5"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"298.6"	"331.2"	"836.6"	"244.9"	"269.6"	"192.0"	"845.8"	"161.1"	"208.8"	"140.3"	"145.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P34896"	"Serine hydroxymethyltransferase, cytosolic OS=Homo sapiens OX=9606 GN=SHMT1 PE=1 SV=1"	"5"	"2"	"6"	"1"	"483"	"53.0"	"7.71"	"1149.41"	"10.58"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00464"	"6470"	"ENSG00000176974; ENSG00000284320"	"SHMT1"	"B4DPM9; D3DXD0; hsa:6470; P34896; Q96HY0; Q9UMD1; Q9UMD2"	"Metabolism of folate and pterines; Carnitine synthesis"	"Glycine metabolism; Folate metabolism; One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways; Clear cell renal cell carcinoma pathways; Male infertility; Neuroinflammation and glutamatergic signaling"	"9"	"0"	"21.0"	"27.8"	"82.2"	"31.9"	"24.7"	"21.2"	"105.7"	"23.0"	"32.1"	"28.2"	"27.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86UP2"	"Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1"	"5"	"6"	"9"	"6"	"1357"	"156.2"	"5.64"	"2078.11"	"10.57"	"6"	"3"	"transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi"	"cytoskeletal activity"	"Pf05104"	"3895"	"ENSG00000126777"	"KTN1"	"B4DZ88; hsa:3895; Q13999; Q14707; Q15387; Q17RZ5; Q5GGW3; Q86UP2; Q86W57"	"RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RND2 GTPase cycle; RHOG GTPase cycle; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; RND3 GTPase cycle; RHO GTPases activate KTN1"	"Glucocorticoid receptor pathway; Nuclear receptors meta-pathway"	"11"	"0"	"293.1"	"258.4"	"996.1"	"252.7"	"208.5"	"167.8"	"1085.8"	"134.8"	"242.9"	"203.9"	"245.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N5N7"	"39S ribosomal protein L50, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL50 PE=1 SV=2"	"25"	"2"	"4"	"2"	"158"	"18.3"	"7.88"	"1069.71"	"10.56"	"2"	"2"	"protein metabolism;other metabolic processes"	"other membranes;cytosol;mitochondrion;translational apparatus"	""	"Pf10501"	"54534"	"ENSG00000136897"	"MRPL50"	"B7Z358; hsa:54534; Q5T7E0; Q8N5N7; Q9NX15"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"23.6"	"16.4"	"71.9"	"21.3"	"20.2"	"18.8"	"61.6"	"11.8"	"10.1"	"18.7"	"11.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00267"	"Transcription elongation factor SPT5 OS=Homo sapiens OX=9606 GN=SUPT5H PE=1 SV=1"	"3"	"3"	"6"	"3"	"1087"	"120.9"	"5.06"	"1215.36"	"10.51"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00467, Pf03439, Pf11942"	"6829"	"ENSG00000196235"	"SUPT5H"	"hsa:6829; O00267; O43279; Q59G52; Q99639"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE"	"Initiation of transcription and translation elongation at the HIV-1 LTR; mRNA processing"	"20"	"0"	"64.2"	"72.9"	"250.9"	"67.2"	"67.8"	"60.1"	"283.0"	"38.7"	"45.8"	"45.6"	"47.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q53EL6"	"Programmed cell death protein 4 OS=Homo sapiens OX=9606 GN=PDCD4 PE=1 SV=2"	"7"	"2"	"6"	"2"	"469"	"51.7"	"5.21"	"1346.52"	"10.50"	"2"	"2"	"developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf02847"	"27250"	"ENSG00000150593"	"PDCD4"	"B2RCV4; B5ME91; hsa:27250; O15501; Q53EL6; Q5VZS6; Q6PJI5; Q8TAR5; Q99834"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	"Translation inhibitors in chronically activated PDGFRA cells; A network map of Macrophage-stimulating protein (MSP) signaling; Interferon type I signaling pathways"	"4"	"0"	"69.1"	"51.0"	"164.2"	"65.9"	"59.6"	"47.0"	"233.6"	"22.3"	"46.1"	"33.3"	"32.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96G61"	"Diphosphoinositol polyphosphate phosphohydrolase 3-beta OS=Homo sapiens OX=9606 GN=NUDT11 PE=1 SV=1"	"20"	"3"	"4"	"2"	"164"	"18.5"	"5.99"	"469.39"	"10.48"	"1"	"3"	"other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00293"	"55190"	"ENSG00000196368"	"NUDT11"	"hsa:55190; Q96G61; Q9NVN0"	"Synthesis of pyrophosphates in the cytosol"	""	"1"	"0"	"46.7"	"52.9"	"186.8"	"60.8"	"66.0"	"83.6"	"282.5"	"104.7"	"226.1"	"373.7"	"708.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13451"	"Peptidyl-prolyl cis-trans isomerase FKBP5 OS=Homo sapiens OX=9606 GN=FKBP5 PE=1 SV=2"	"11"	"3"	"6"	"3"	"457"	"51.2"	"5.90"	"1135.56"	"10.44"	"2"	"3"	"other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00254, Pf00515"	"2289"	"ENSG00000096060"	"FKBP5"	"F5H7R1; hsa:2289; Q13451; Q59EB8; Q5TGM6"	"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; ESR-mediated signaling; MECP2 regulates neuronal receptors and channels"	"Androgen receptor network in prostate cancer; Farnesoid X receptor pathway; Nuclear receptors meta-pathway; MECP2 and associated Rett syndrome"	"7"	"0"	"156.5"	"172.7"	"573.8"	"188.4"	"173.2"	"154.7"	"679.6"	"93.0"	"138.3"	"119.3"	"102.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13619"	"Cullin-4A OS=Homo sapiens OX=9606 GN=CUL4A PE=1 SV=3"	"5"	"4"	"8"	"1"	"759"	"87.6"	"8.13"	"1383.78"	"10.34"	"4"	"4"	"cell cycle OR cell proliferation;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00888, Pf10557"	"8451"	"ENSG00000139842"	"CUL4A"	"A2A2W2; hsa:8451; O75834; Q13619; Q589T6; Q5TC62; Q6UP08; Q9UP17"	"Neddylation; Formation of Incision Complex in GG-NER; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Recognition of DNA damage by PCNA-containing replication complex; DNA Damage Recognition in GG-NER; Dual Incision in GG-NER"	"Hippo-Merlin signaling dysregulation; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"13"	"0"	"23.3"	"40.0"	"98.3"	"29.4"	"21.0"	"20.4"	"106.1"	"29.9"	"26.5"	"28.4"	"37.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NW08"	"DNA-directed RNA polymerase III subunit RPC2 OS=Homo sapiens OX=9606 GN=POLR3B PE=1 SV=2"	"3"	"3"	"6"	"3"	"1133"	"127.7"	"8.50"	"701.24"	"10.33"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00562, Pf04560, Pf04561, Pf04563, Pf04565, Pf04566, Pf04567"	"55703"	"ENSG00000013503"	"POLR3B"	"A8K6H0; B3KV73; F5H1E6; hsa:55703; Q9NW08; Q9NW59"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation"	"Pyrimidine metabolism; Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway"	"10"	"0"	"1992.5"	"472.6"	"910.5"	"598.6"	"146.6"	"135.2"	"459.4"	"71.7"	"68.9"	"57.9"	"60.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60885"	"Bromodomain-containing protein 4 OS=Homo sapiens OX=9606 GN=BRD4 PE=1 SV=2"	"2"	"3"	"5"	"3"	"1362"	"152.1"	"9.19"	"921.02"	"10.33"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00439, Pf17035, Pf17105"	"23476"	"ENSG00000141867"	"BRD4"	"hsa:23476; O60433; O60885; Q4G0X8; Q86YS8; Q96PD3"	"Potential therapeutics for SARS"	"VEGFA-VEGFR2 signaling; 7q11.23 copy number variation syndrome"	"3"	"0"	"95.6"	"70.9"	"176.8"	"99.0"	"107.6"	"92.4"	"266.6"	"80.7"	"117.6"	"95.7"	"90.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P28070"	"Proteasome subunit beta type-4 OS=Homo sapiens OX=9606 GN=PSMB4 PE=1 SV=4"	"9"	"1"	"2"	"1"	"264"	"29.2"	"5.97"	""	"10.32"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00227"	"5692"	"ENSG00000159377"	"PSMB4"	"B2R9L3; hsa:5692; P28070; P31148; Q5SZS5; Q6IBI4; Q969L6"	"Regulation of expression of SLITs and ROBOs; Regulation of PTEN stability and activity; KEAP1-NFE2L2 pathway; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Neddylation; Interleukin-1 signaling; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"62"	"0"	"29.2"	"26.7"	"66.4"	"18.9"	"19.8"	"11.6"	"66.1"	"34.2"	"30.7"	"28.0"	"26.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O96000"	"NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 OS=Homo sapiens OX=9606 GN=NDUFB10 PE=1 SV=3"	"27"	"3"	"6"	"3"	"172"	"20.8"	"8.48"	"1226.33"	"10.30"	"3"	"3"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf10249"	"4716"	"ENSG00000140990"	"NDUFB10"	"hsa:4716; O96000; Q96II6"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Modulators of TCR signaling and T cell activation; Oxidative phosphorylation"	"6"	"0"	"67.2"	"78.7"	"300.4"	"61.2"	"46.0"	"32.2"	"310.3"	"19.6"	"31.5"	"18.2"	"21.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49773"	"Histidine triad nucleotide-binding protein 1 OS=Homo sapiens OX=9606 GN=HINT1 PE=1 SV=2"	"11"	"1"	"6"	"1"	"126"	"13.8"	"6.95"	"1369.24"	"10.29"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf01230"	"3094"	"ENSG00000169567"	"HINT1"	"hsa:3094; P49773; Q9H5W8"	""	""	"0"	"0"	"171.6"	"221.0"	"1129.7"	"193.9"	"189.5"	"124.8"	"1647.7"	"176.9"	"187.2"	"122.6"	"146.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13155"	"Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 OS=Homo sapiens OX=9606 GN=AIMP2 PE=1 SV=2"	"15"	"5"	"7"	"5"	"320"	"35.3"	"8.22"	"1420.16"	"10.25"	"4"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf14497, Pf16780, Pf18569"	"7965"	"ENSG00000106305"	"AIMP2"	"F8W950; hsa:7965; Q13155; Q75MR1; Q96CZ5; Q9P1L2"	"Cytosolic tRNA aminoacylation; Selenoamino acid metabolism"	"Osteoclast signaling; Transcriptional activation by NRF2 in response to phytochemicals; NRF2-ARE regulation"	"5"	"0"	"402.5"	"416.1"	"1623.9"	"372.1"	"402.0"	"289.1"	"1495.6"	"179.7"	"291.9"	"259.8"	"240.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UNZ2"	"NSFL1 cofactor p47 OS=Homo sapiens OX=9606 GN=NSFL1C PE=1 SV=2"	"12"	"4"	"7"	"4"	"370"	"40.5"	"5.10"	"1537.79"	"10.21"	"4"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00789, Pf08059, Pf14555"	"55968"	"ENSG00000088833"	"NSFL1C"	"A2A2L1; B2RD74; hsa:55968; Q5JXA4; Q5JXA5; Q7Z533; Q9H102; Q9NVL9; Q9UI06; Q9UNZ2"	"RHOH GTPase cycle"	"Alstrom syndrome"	"2"	"0"	"131.9"	"168.7"	"537.3"	"148.8"	"161.0"	"120.0"	"702.5"	"111.3"	"161.5"	"113.8"	"95.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62495"	"Eukaryotic peptide chain release factor subunit 1 OS=Homo sapiens OX=9606 GN=ETF1 PE=1 SV=3"	"11"	"5"	"9"	"5"	"437"	"49.0"	"5.71"	"1458.46"	"10.19"	"5"	"4"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"enzyme regulator activity;translation activity;nucleic acid binding activity;other molecular function"	"Pf03463, Pf03464, Pf03465"	"2107"	"ENSG00000120705"	"ETF1"	"B2R6B4; D3DQC1; hsa:2107; P46055; P62495; Q5M7Z7; Q96CG1"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Translation factors"	"5"	"0"	"373.1"	"358.7"	"1298.7"	"343.1"	"297.5"	"235.5"	"1727.2"	"370.1"	"474.3"	"450.9"	"546.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63220"	"40S ribosomal protein S21 OS=Homo sapiens OX=9606 GN=RPS21 PE=1 SV=1"	"31"	"3"	"9"	"3"	"83"	"9.1"	"8.50"	"1685.87"	"10.14"	"3"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01249"	"6227"	"ENSG00000171858"	"RPS21"	"hsa:6227; P35265; P63220"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"1060.2"	"1122.2"	"3177.3"	"846.6"	"854.4"	"775.3"	"3087.4"	"411.1"	"604.4"	"442.5"	"432.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q53GS9"	"U4/U6.U5 tri-snRNP-associated protein 2 OS=Homo sapiens OX=9606 GN=USP39 PE=1 SV=2"	"10"	"5"	"9"	"4"	"565"	"65.3"	"8.91"	"1509.45"	"10.12"	"5"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00443, Pf02148"	"10713"	"ENSG00000168883"	"USP39"	"A8K086; B3KM40; B4DHT4; D6W5L4; G5E9H0; hsa:10713; Q53GS9; Q6NX47; Q96RK9; Q9BV89; Q9H381; Q9P050; Q9Y310"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"82.1"	"81.5"	"257.6"	"78.7"	"68.1"	"51.2"	"305.8"	"69.7"	"78.9"	"84.6"	"119.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H9J2"	"39S ribosomal protein L44, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL44 PE=1 SV=1"	"8"	"3"	"6"	"3"	"332"	"37.5"	"8.40"	"1011.98"	"10.12"	"3"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"plasma membrane;other membranes;mitochondrion;translational apparatus;nucleus"	"nucleic acid binding activity;other molecular function"	""	"65080"	"ENSG00000135900"	"MRPL44"	"hsa:65080; Q53S16; Q6IA62; Q9H821; Q9H9J2"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"335.7"	"370.8"	"1024.9"	"338.3"	"312.8"	"260.0"	"1225.5"	"154.9"	"285.2"	"221.1"	"219.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q00796"	"Sorbitol dehydrogenase OS=Homo sapiens OX=9606 GN=SORD PE=1 SV=4"	"10"	"3"	"8"	"3"	"357"	"38.3"	"7.97"	"1268.31"	"10.12"	"3"	"3"	"other metabolic processes;stress response;other biological processes"	"non-structural extracellular;other membranes;cytosol;cytoskeleton;mitochondrion"	"other molecular function"	"Pf00107, Pf08240"	"6652"	"ENSG00000140263"	"SORD"	"B2R655; B7Z3A6; hsa:6652; J3JZZ5; Q00796; Q16682; Q9UMD6"	"Formation of xylulose-5-phosphate; Fructose biosynthesis"	"Disorders of fructose metabolism; Polyol pathway"	"4"	"0"	"211.1"	"219.0"	"806.3"	"187.0"	"166.5"	"147.3"	"869.2"	"120.8"	"199.3"	"178.2"	"203.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P45880"	"Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2"	"12"	"3"	"6"	"3"	"294"	"31.5"	"7.56"	"1019.65"	"10.11"	"3"	"3"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"other membranes;cytoskeleton;mitochondrion;other cell component"	"transporter activity;other molecular function"	"Pf01459"	"7417"	"ENSG00000165637"	"VDAC2"	"hsa:7417; P45880; Q5VWK1; Q5VWK3; Q6IB40; Q7L3J5; Q9BWK8; Q9Y5I6"	"Ub-specific processing proteases; Mitochondrial calcium ion transport"	"Alzheimer's disease and miRNA effects; Ferroptosis; Alzheimer's disease"	"5"	"0"	"187.9"	"194.2"	"870.0"	"172.0"	"151.5"	"104.6"	"653.8"	"60.4"	"95.8"	"71.2"	"77.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P53597"	"Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLG1 PE=1 SV=4"	"12"	"3"	"5"	"3"	"346"	"36.2"	"8.79"	"782.96"	"10.09"	"2"	"3"	"other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf00549, Pf02629"	"8802"	"ENSG00000163541"	"SUCLG1"	"hsa:8802; P53597; Q9BWB0; Q9UNP6"	"Citric acid cycle (TCA cycle)"	"Amino acid metabolism; TCA cycle (aka Krebs or citric acid cycle)"	"3"	"0"	"275.9"	"307.3"	"1034.8"	"248.2"	"225.7"	"158.2"	"1265.2"	"147.5"	"234.6"	"165.2"	"160.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P17858"	"ATP-dependent 6-phosphofructokinase, liver type OS=Homo sapiens OX=9606 GN=PFKL PE=1 SV=6"	"5"	"4"	"6"	"2"	"780"	"85.0"	"7.50"	"894.29"	"10.06"	"3"	"3"	"other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00365"	"5211"	"ENSG00000141959"	"PFKL"	"hsa:5211; P17858; Q96A64; Q96IH4; Q9BR91"	"Neutrophil degranulation; Glycolysis"	"Photodynamic therapy-induced HIF-1 survival signaling; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Insulin signaling; Disorders of fructose metabolism; Glycolysis and gluconeogenesis"	"8"	"0"	"74.0"	"77.3"	"306.8"	"77.2"	"89.6"	"70.7"	"308.2"	"43.0"	"73.0"	"55.9"	"37.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P21953"	"2-oxoisovalerate dehydrogenase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=BCKDHB PE=1 SV=2"	"12"	"4"	"6"	"4"	"392"	"43.1"	"6.29"	"1184.33"	"10.02"	"3"	"3"	"other metabolic processes;other biological processes"	"mitochondrion;nucleus"	"other molecular function"	"Pf02779, Pf02780"	"594"	"ENSG00000083123"	"BCKDHB"	"hsa:594; P21953; Q5T2J3; Q9BQL0"	"Glyoxylate metabolism and glycine degradation; Branched-chain amino acid catabolism"	"Primary ovarian insufficiency"	"3"	"0"	"346.4"	"328.1"	"673.7"	"337.6"	"338.4"	"290.8"	"527.0"	"100.7"	"196.6"	"152.0"	"132.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25098"	"Beta-adrenergic receptor kinase 1 OS=Homo sapiens OX=9606 GN=GRK2 PE=1 SV=2"	"7"	"4"	"7"	"4"	"689"	"79.5"	"7.28"	"1287.29"	"10.01"	"4"	"3"	"cell-cell signaling;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"signal transduction activity or receptor binding;kinase activity;other molecular function"	"Pf00069, Pf00169, Pf00615"	"156"	"ENSG00000173020"	"GRK2"	"B0ZBE1; hsa:156; P25098; Q13837; Q6GTT3"	"G alpha (q) signalling events; Activation of SMO; G alpha (s) signalling events; Cargo recognition for clathrin-mediated endocytosis; Calmodulin induced events"	"Chemokine signaling pathway; Hedgehog signaling pathway; Hedgehog signaling pathway"	"8"	"0"	"110.4"	"116.7"	"448.8"	"155.0"	"116.1"	"95.4"	"430.2"	"86.6"	"206.4"	"253.0"	"377.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05556"	"Integrin beta-1 OS=Homo sapiens OX=9606 GN=ITGB1 PE=1 SV=2"	"2"	"1"	"4"	"1"	"798"	"88.4"	"5.39"	"1219.27"	"9.99"	"1"	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00362, Pf07965, Pf07974, Pf08725, Pf17205, Pf18372"	"3688"	"ENSG00000150093"	"ITGB1"	"A8K6N2; D3DRX9; D3DRY3; D3DRY4; D3DRY5; hsa:3688; P05556; P78466; P78467; Q13089; Q13090; Q13091; Q13212; Q14622; Q14647; Q29RW2; Q7Z3V1; Q8WUM6"	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell; Potential therapeutics for SARS; RAC1 GTPase cycle; RHOG GTPase cycle; RHO GTPases Activate Formins; HCMV Early Events; RAC2 GTPase cycle; RAC3 GTPase cycle; Integrin cell surface interactions; ECM proteoglycans; GPER1 signaling; CHL1 interactions; Interleukin-4 and Interleukin-13 signaling; Signal transduction by L1; Syndecan interactions; Other semaphorin interactions; Laminin interactions; MET activates PTK2 signaling; Basigin interactions; Platelet Adhesion to exposed collagen; Molecules associated with elastic fibres; TGF-beta receptor signaling activates SMADs; Fibronectin matrix formation; Localization of the PINCH-ILK-PARVIN complex to focal adhesions; MET interacts with TNS proteins"	"Integrin-mediated cell adhesion; Prolactin signaling pathway; Neural crest differentiation; Arrhythmogenic right ventricular cardiomyopathy; Pathogenic Escherichia coli infection; Primary focal segmental glomerulosclerosis (FSGS); Mammary gland development pathway - Embryonic development (Stage 1 of 4); Focal adhesion; Hepatocyte growth factor receptor signaling; RAC1/PAK1/p38/MMP2 pathway; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; VEGFA-VEGFR2 signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Ebola virus infection in host; Cells and molecules involved in local acute inflammatory response ; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Small cell lung cancer; Gastrin signaling pathway; Genes controlling nephrogenesis; Development of ureteric collection system; Pleural mesothelioma; CCL18 signaling pathway; GDNF signaling; TROP2 regulatory signaling; 11p11.2 copy number variation syndrome ; A network map of Macrophage-stimulating protein (MSP) signaling"	"54"	"0"	"57.3"	"63.4"	"268.3"	"54.0"	"51.4"	"37.7"	"309.4"	"31.5"	"46.8"	"31.6"	"29.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99575"	"Ribonucleases P/MRP protein subunit POP1 OS=Homo sapiens OX=9606 GN=POP1 PE=1 SV=2"	"3"	"3"	"6"	"3"	"1024"	"114.6"	"9.22"	"572.73"	"9.98"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06978, Pf08170"	"10940"	"ENSG00000104356"	"POP1"	"A8K5W9; hsa:10940; Q15037; Q99575"	"tRNA processing in the nucleus"	""	"1"	"0"	"262.2"	"258.5"	"2011.3"	"604.8"	"394.4"	"310.6"	"1882.8"	"101.8"	"189.7"	"143.6"	"110.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14011"	"Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1"	"19"	"2"	"3"	"2"	"172"	"18.6"	"9.51"	"353.52"	"9.97"	"1"	"2"	"cell organization and biogenesis;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"1153"	"ENSG00000099622"	"CIRBP"	"B3KT17; B4E2X2; hsa:1153; Q14011"	""	""	"0"	"0"	"170.4"	"176.8"	"375.7"	"169.3"	"160.5"	"140.7"	"522.7"	"130.1"	"192.4"	"158.7"	"159.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15143"	"Actin-related protein 2/3 complex subunit 1B OS=Homo sapiens OX=9606 GN=ARPC1B PE=1 SV=3"	"10"	"2"	"3"	"1"	"372"	"40.9"	"8.35"	"469.30"	"9.96"	"1"	"2"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400"	"10095"	"ENSG00000130429"	"ARPC1B"	"hsa:10095; O15143; Q9BU00"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; EPHB-mediated forward signaling"	"Pathogenic Escherichia coli infection; Microglia pathogen phagocytosis pathway"	"6"	"0"	"64.7"	"58.4"	"204.5"	"45.2"	"33.0"	"25.0"	"187.9"	"54.1"	"99.7"	"127.3"	"282.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P53041"	"Serine/threonine-protein phosphatase 5 OS=Homo sapiens OX=9606 GN=PPP5C PE=1 SV=1"	"8"	"3"	"6"	"3"	"499"	"56.8"	"6.28"	"1036.51"	"9.94"	"3"	"3"	"cell cycle OR cell proliferation;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00149, Pf00515, Pf08321"	"5536"	"ENSG00000011485"	"PPP5C"	"hsa:5536; P53041; Q16722; Q53XV2"	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Negative regulation of MAPK pathway; ESR-mediated signaling"	"MAPK signaling pathway; ATM signaling in development and disease"	"5"	"0"	"60.4"	"77.9"	"253.8"	"78.2"	"68.7"	"46.2"	"251.7"	"39.0"	"50.3"	"60.9"	"122.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P17812"	"CTP synthase 1 OS=Homo sapiens OX=9606 GN=CTPS1 PE=1 SV=2"	"10"	"5"	"7"	"5"	"591"	"66.6"	"6.46"	"867.53"	"9.92"	"3"	"4"	"cell cycle OR cell proliferation;other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00117, Pf06418"	"1503"	"ENSG00000171793"	"CTPS1"	"B4DR64; D3DPW1; hsa:1503; P17812; Q5VW67; Q96GK6"	"Interconversion of nucleotide di- and triphosphates"	"Pyrimidine metabolism"	"2"	"0"	"199.3"	"264.9"	"790.9"	"231.1"	"236.8"	"220.5"	"1060.9"	"162.5"	"222.0"	"195.7"	"200.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NS69"	"Mitochondrial import receptor subunit TOM22 homolog OS=Homo sapiens OX=9606 GN=TOMM22 PE=1 SV=3"	"34"	"3"	"4"	"3"	"142"	"15.5"	"4.34"	"248.07"	"9.90"	"1"	"3"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity"	"Pf04281"	"56993"	"ENSG00000100216"	"TOMM22"	"hsa:56993; Q9NS69"	"PINK1-PRKN Mediated Mitophagy; Mitochondrial protein import"	""	"2"	"0"	"62.9"	"64.6"	"192.8"	"51.2"	"54.5"	"40.9"	"209.8"	"42.5"	"57.6"	"47.0"	"53.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UJW0"	"Dynactin subunit 4 OS=Homo sapiens OX=9606 GN=DCTN4 PE=1 SV=1"	"7"	"2"	"4"	"2"	"460"	"52.3"	"7.34"	"717.89"	"9.89"	"2"	"2"	""	"cytosol;cytoskeleton;nucleus;other cell component"	""	"Pf05502"	"51164"	"ENSG00000132912"	"DCTN4"	"B3KWW0; D3DQH0; E5RGT5; hsa:51164; Q8TAN8; Q9UJW0"	"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; MHC class II antigen presentation; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic"	""	"4"	"0"	"70.6"	"64.3"	"202.0"	"73.9"	"60.9"	"52.3"	"259.7"	"56.4"	"62.0"	"60.5"	"53.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04844"	"Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Homo sapiens OX=9606 GN=RPN2 PE=1 SV=3"	"5"	"2"	"5"	"2"	"631"	"69.2"	"5.69"	"765.91"	"9.88"	"1"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;ER/Golgi;nucleus;other cytoplasmic organelle"	"translation activity"	"Pf05817"	"6185"	"ENSG00000118705"	"RPN2"	"hsa:6185; P04844; Q5JYR6; Q6IBA5; Q96E21; Q9BUQ3; Q9UBE1"	"SRP-dependent cotranslational protein targeting to membrane; Asparagine N-linked glycosylation; Maturation of spike protein"	"Proteasome degradation; N-glycan biosynthesis"	"5"	"0"	"115.6"	"103.8"	"363.0"	"95.7"	"88.5"	"63.6"	"341.6"	"53.0"	"78.7"	"47.8"	"57.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19623"	"Spermidine synthase OS=Homo sapiens OX=9606 GN=SRM PE=1 SV=1"	"12"	"3"	"6"	"3"	"302"	"33.8"	"5.49"	"1224.41"	"9.87"	"3"	"3"	"other metabolic processes;other biological processes"	"cytosol"	"other molecular function"	"Pf01564, Pf17284"	"6723"	"ENSG00000116649"	"SRM"	"B1AKP9; hsa:6723; P19623; Q15511"	"Metabolism of polyamines"	"Methionine de novo and salvage pathway; Amino acid metabolism"	"3"	"0"	"76.6"	"147.4"	"449.3"	"131.0"	"127.1"	"113.3"	"477.2"	"98.9"	"102.6"	"94.2"	"103.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14324"	"Farnesyl pyrophosphate synthase OS=Homo sapiens OX=9606 GN=FDPS PE=1 SV=4"	"9"	"3"	"7"	"3"	"419"	"48.2"	"6.15"	"1299.61"	"9.86"	"3"	"2"	"other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00348"	"2224"	"ENSG00000160752"	"FDPS"	"D3DV91; E9PCI9; hsa:2224; P14324; Q96G29"	"Activation of gene expression by SREBF (SREBP); Cholesterol biosynthesis"	"Cholesterol biosynthesis pathway; Sterol regulatory element-binding proteins (SREBP) signaling; Mevalonate pathway; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Cholesterol synthesis disorders; Cholesterol metabolism; Enterocyte cholesterol metabolism"	"9"	"0"	"103.0"	"103.4"	"464.2"	"86.3"	"107.0"	"71.4"	"619.7"	"65.0"	"80.6"	"60.6"	"51.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62314"	"Small nuclear ribonucleoprotein Sm D1 OS=Homo sapiens OX=9606 GN=SNRPD1 PE=1 SV=1"	"37"	"3"	"6"	"3"	"119"	"13.3"	"11.56"	"770.45"	"9.82"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01423"	"6632"	"ENSG00000167088"	"SNRPD1"	"B5BTZ1; hsa:6632; P13641; P62314"	"mRNA Splicing - Major Pathway; SARS-CoV-2 modulates host translation machinery; snRNP Assembly; mRNA Splicing - Minor Pathway"	"mRNA processing"	"5"	"0"	"101.4"	"128.0"	"315.6"	"104.6"	"133.3"	"94.6"	"545.0"	"80.9"	"89.7"	"92.2"	"67.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82664"	"28S ribosomal protein S10, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS10 PE=1 SV=2"	"16"	"2"	"4"	"2"	"201"	"23.0"	"8.00"	"1231.20"	"9.77"	"2"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	""	"Pf00338"	"55173"	"ENSG00000048544"	"MRPS10"	"B2RE89; hsa:55173; P82664; Q9H3E5; Q9NVR3"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"97.8"	"95.5"	"299.9"	"101.5"	"84.7"	"76.0"	"302.8"	"32.8"	"63.6"	"42.2"	"43.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60645"	"Exocyst complex component 3 OS=Homo sapiens OX=9606 GN=EXOC3 PE=1 SV=3"	"3"	"3"	"6"	"3"	"745"	"85.5"	"6.29"	"1095.23"	"9.77"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf06046"	"11336"	"ENSG00000180104"	"EXOC3"	"hsa:11336; O60645; Q6P2E8; Q8TEN6; Q8WUW0; Q96DI4"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"Ciliary landscape"	"4"	"0"	"37.2"	"36.0"	"97.0"	"27.1"	"29.8"	"32.8"	"98.6"	"21.5"	"99.1"	"114.6"	"105.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22033"	"Methylmalonyl-CoA mutase, mitochondrial OS=Homo sapiens OX=9606 GN=MMUT PE=1 SV=4"	"5"	"3"	"6"	"3"	"750"	"83.1"	"6.93"	"941.18"	"9.76"	"3"	"3"	"other metabolic processes;developmental processes;other biological processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf01642, Pf02310"	"4594"	"ENSG00000146085"	"MMUT"	"A8K953; hsa:4594; P22033; Q5SYZ3; Q96B11; Q9UD64"	"Propionyl-CoA catabolism; Defective MMAA causes MMA, cblA type; Defective MUT causes MMAM; Cobalamin (Cbl) metabolism"	"Vitamin B12 metabolism; Amino acid metabolism"	"6"	"0"	"84.9"	"86.4"	"277.7"	"102.0"	"88.9"	"66.0"	"333.3"	"68.3"	"161.5"	"284.0"	"472.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BRP8"	"Partner of Y14 and mago OS=Homo sapiens OX=9606 GN=PYM1 PE=1 SV=1"	"21"	"3"	"6"	"3"	"204"	"22.6"	"9.45"	"878.34"	"9.75"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity"	"Pf09282"	"84305"	"ENSG00000170473"	"PYM1"	"B6ZDM5; hsa:84305; Q8IXJ8; Q8N8E7; Q9BRP8"	""	""	"0"	"0"	"91.6"	"93.0"	"289.9"	"80.6"	"97.3"	"67.2"	"349.2"	"66.1"	"122.1"	"123.4"	"171.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BZZ5"	"Apoptosis inhibitor 5 OS=Homo sapiens OX=9606 GN=API5 PE=1 SV=3"	"6"	"3"	"6"	"3"	"524"	"59.0"	"7.34"	"997.22"	"9.75"	"3"	"3"	"other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf05918"	"8539"	"ENSG00000166181"	"API5"	"B4DGR0; B4DRJ2; B4E283; D3DR21; G3V1C3; hsa:8539; O15441; Q9BZZ5; Q9Y4J7"	""	""	"0"	"0"	"233.2"	"252.2"	"1028.8"	"216.4"	"211.1"	"130.6"	"965.1"	"113.0"	"196.4"	"138.8"	"146.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NX24"	"H/ACA ribonucleoprotein complex subunit 2 OS=Homo sapiens OX=9606 GN=NHP2 PE=1 SV=1"	"12"	"1"	"4"	"1"	"153"	"17.2"	"8.22"	"1307.03"	"9.74"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf01248"	"55651"	"ENSG00000145912"	"NHP2"	"A6NKY8; hsa:55651; Q9NX24; Q9P095"	"rRNA modification in the nucleus and cytosol; Telomere Extension By Telomerase"	""	"2"	"0"	"46.8"	"50.6"	"159.6"	"38.8"	"42.3"	"41.7"	"182.2"	"38.3"	"142.7"	"154.0"	"151.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q02809"	"Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 OS=Homo sapiens OX=9606 GN=PLOD1 PE=1 SV=2"	"5"	"3"	"6"	"3"	"727"	"83.5"	"6.95"	"960.68"	"9.67"	"3"	"3"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf03171"	"5351"	"ENSG00000083444"	"PLOD1"	"B4DR87; hsa:5351; Q02809; Q96AV9; Q9H132"	"Collagen biosynthesis and modifying enzymes"	"Type I collagen synthesis in the context of osteogenesis imperfecta"	"2"	"0"	"54.0"	"68.5"	"193.7"	"67.0"	"78.3"	"55.7"	"231.4"	"54.7"	"76.8"	"67.9"	"53.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94776"	"Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1"	"5"	"3"	"6"	"3"	"668"	"75.0"	"9.66"	"1067.13"	"9.66"	"3"	"3"	"cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00320, Pf01426, Pf01448, Pf17226"	"9219"	"ENSG00000149480"	"MTA2"	"hsa:9219; O94776; Q68DB1; Q9UQB5"	"Potential therapeutics for SARS; Regulation of PTEN gene transcription; HDACs deacetylate histones; RNA Polymerase I Transcription Initiation; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of TP53 Activity through Acetylation"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"7"	"0"	"110.5"	"131.9"	"474.9"	"128.7"	"121.0"	"83.3"	"503.5"	"55.8"	"82.4"	"67.7"	"74.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z2W9"	"39S ribosomal protein L21, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL21 PE=1 SV=2"	"17"	"4"	"7"	"4"	"205"	"22.8"	"9.89"	"1332.24"	"9.64"	"4"	"3"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00829"	"219927"	"ENSG00000197345"	"MRPL21"	"A6NKU0; C9JPR2; hsa:219927; Q7Z2W9"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"129.1"	"166.6"	"468.7"	"149.5"	"147.0"	"114.5"	"563.3"	"94.1"	"115.3"	"111.8"	"120.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95292"	"Vesicle-associated membrane protein-associated protein B/C OS=Homo sapiens OX=9606 GN=VAPB PE=1 SV=3"	"18"	"3"	"6"	"2"	"243"	"27.2"	"7.30"	"1240.33"	"9.64"	"3"	"3"	"cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00635"	"9217"	"ENSG00000124164"	"VAPB"	"A2A2F2; hsa:9217; O95292; O95293; Q9P0H0"	"RHOC GTPase cycle; RHOA GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RHOD GTPase cycle; Sphingolipid de novo biosynthesis"	"Ciliary landscape"	"7"	"0"	"95.5"	"87.0"	"370.2"	"82.6"	"89.6"	"67.3"	"408.9"	"31.8"	"71.0"	"62.2"	"59.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6UN15"	"Pre-mRNA 3'-end-processing factor FIP1 OS=Homo sapiens OX=9606 GN=FIP1L1 PE=1 SV=1"	"3"	"1"	"4"	"1"	"594"	"66.5"	"5.59"	"1107.61"	"9.63"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	""	"Pf05182"	"81608"	"ENSG00000145216"	"FIP1L1"	"B4DIR3; G3XAD6; hsa:81608; Q0VGE0; Q499Y4; Q49AU3; Q6UN15; Q7Z608; Q8WVN3; Q96F80; Q9H077"	"Transport of Mature mRNA Derived from an Intronless Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs; Signaling by cytosolic PDGFRA and PDGFRB fusion proteins"	""	"6"	"0"	"12.2"	"19.6"	"71.0"	"23.2"	"22.4"	"16.8"	"107.7"	"14.8"	"23.2"	"16.2"	"13.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96A72"	"Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1"	"20"	"3"	"6"	"3"	"148"	"17.3"	"6.39"	"1043.91"	"9.62"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf02792"	"55110"	"ENSG00000111196"	"MAGOHB"	"hsa:55110; Q96A72"	"Regulation of expression of SLITs and ROBOs; mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	""	"6"	"0"	"24.9"	"32.8"	"210.0"	"26.0"	"31.0"	"24.6"	"142.0"	"6.6"	"13.1"	"9.3"	"8.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P43243"	"Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2"	"5"	"4"	"7"	"4"	"847"	"94.6"	"6.25"	"1271.81"	"9.60"	"4"	"3"	"stress response;developmental processes;other biological processes"	"other membranes;nucleus"	"nucleic acid binding activity;other molecular function"	""	"9782"	"ENSG00000015479"	"MATR3"	"B7ZAV5; D3DQC3; hsa:9782; P43243; Q9UHW0; Q9UQ27"	""	""	"0"	"0"	"165.7"	"171.8"	"525.1"	"154.0"	"156.2"	"131.6"	"577.1"	"74.3"	"141.6"	"103.0"	"110.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96I99"	"Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLG2 PE=1 SV=2"	"9"	"4"	"7"	"4"	"432"	"46.5"	"6.39"	"855.59"	"9.56"	"3"	"4"	"other metabolic processes"	"plasma membrane;other membranes;mitochondrion;other cell component"	"other molecular function"	"Pf00549, Pf08442"	"8801"	"ENSG00000172340"	"SUCLG2"	"C9JVT2; hsa:8801; O95195; Q6NUH7; Q86VX8; Q8WUQ1; Q96I99"	"Citric acid cycle (TCA cycle)"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Metabolic reprogramming in colon cancer; TCA cycle (aka Krebs or citric acid cycle)"	"4"	"0"	"84.3"	"82.1"	"351.4"	"89.6"	"64.3"	"49.2"	"427.2"	"55.7"	"61.6"	"51.1"	"57.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14929"	"Histone acetyltransferase type B catalytic subunit OS=Homo sapiens OX=9606 GN=HAT1 PE=1 SV=1"	"11"	"3"	"6"	"3"	"419"	"49.5"	"5.69"	"1083.91"	"9.54"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf10394"	"100598934; 100970485; 102127119; 103217315; 104673520; 105548069; 105579802; 695933"	"ENSCATG00000044185; ENSCSAG00000014790; ENSMFAG00000044656; ENSMLEG00000030988; ENSMMUG00000007313; ENSNLEG00000031960; ENSPPAG00000043422; ENSPPYG00000012932; ENSPTEG00000037699; ENSPTRG00000012637; ENSRROG00000043073; ENSTGEG00000018560"	"HAT1"	"A0A0D9RQL6; A0A2I3GP06; A0A2J8PQW8; A0A2J8VQX1; A0A2K5P0H4; A0A2K5VNP4; A0A2K5YDV9; A0A2K6REU7; A0A2R9CI71; A0A663DCK2; A0A6D2WXR9; A0A8C9IWX6; A0A8D2FM88; A0A8J8XV08; A0A8J8YED4; caty:105579802; csab:103217315; F7GNR2; F7GNT9; G7N8B0; G7PKT8; H2P7T9; H2QIZ3; mcc:695933; mcf:102127119; mleu:105548069; nle:100598934; pps:100970485; rro:104673520"	""	""	"0"	"0"	"145.2"	"211.1"	"851.1"	"224.0"	"181.1"	"151.7"	"745.6"	"94.6"	"127.1"	"123.8"	"99.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96CN7"	"Isochorismatase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ISOC1 PE=1 SV=3"	"10"	"2"	"6"	"2"	"298"	"32.2"	"7.39"	"903.78"	"9.51"	"2"	"2"	""	"other cytoplasmic organelle;other cell component"	""	"Pf00857"	"51015"	"ENSG00000066583"	"ISOC1"	"hsa:51015; Q7Z770; Q96CN7"	""	""	"0"	"0"	"102.2"	"100.9"	"344.8"	"96.7"	"90.5"	"61.8"	"281.0"	"57.2"	"80.3"	"49.5"	"55.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P24666"	"Low molecular weight phosphotyrosine protein phosphatase OS=Homo sapiens OX=9606 GN=ACP1 PE=1 SV=3"	"22"	"4"	"8"	"4"	"158"	"18.0"	"6.74"	"1995.87"	"9.48"	"4"	"3"	"protein metabolism;other metabolic processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf01451"	"52"	"ENSG00000143727"	"ACP1"	"A8K1L9; B5MCC7; hsa:52; P24666; P24667; Q16035; Q16036; Q16725; Q3KQX8; Q53RU0"	""	"VEGFA-VEGFR2 signaling; 11p11.2 copy number variation syndrome"	"2"	"0"	"163.5"	"182.5"	"705.1"	"186.6"	"199.0"	"164.3"	"1035.4"	"138.4"	"218.7"	"153.8"	"139.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y371"	"Endophilin-B1 OS=Homo sapiens OX=9606 GN=SH3GLB1 PE=1 SV=1"	"14"	"3"	"4"	"3"	"365"	"40.8"	"6.04"	"694.75"	"9.47"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf03114, Pf14604"	"51100"	"ENSG00000097033"	"SH3GLB1"	"B4E182; hsa:51100; Q5H8U5; Q9H3Z0; Q9NR47; Q9NYA9; Q9Y371"	""	"Nanoparticle triggered autophagic cell death"	"1"	"0"	"32.8"	"34.5"	"206.7"	"39.0"	"40.5"	"13.0"	"439.5"	"23.8"	"27.7"	"18.0"	"22.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BPX5"	"Actin-related protein 2/3 complex subunit 5-like protein OS=Homo sapiens OX=9606 GN=ARPC5L PE=1 SV=1"	"33"	"2"	"3"	"2"	"153"	"16.9"	"6.60"	"450.27"	"9.46"	"1"	"2"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf04699"	"81873"	"ENSG00000136950"	"ARPC5L"	"hsa:81873; Q7Z523; Q9BPX5"	""	"Pathogenic Escherichia coli infection; VEGFA-VEGFR2 signaling"	"2"	"0"	"50.3"	"48.6"	"159.0"	"43.7"	"31.3"	"20.2"	"158.2"	"53.4"	"83.3"	"172.0"	"316.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96AY3"	"Peptidyl-prolyl cis-trans isomerase FKBP10 OS=Homo sapiens OX=9606 GN=FKBP10 PE=1 SV=1"	"8"	"4"	"6"	"4"	"582"	"64.2"	"5.62"	"1079.42"	"9.46"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes"	"other membranes;mitochondrion;ER/Golgi"	"other molecular function"	"Pf00254, Pf13202"	"60681"	"ENSG00000141756"	"FKBP10"	"hsa:60681; Q7Z3R4; Q96AY3; Q9H3N3; Q9H6J3; Q9H6N5; Q9UF89"	""	"Type I collagen synthesis in the context of osteogenesis imperfecta"	"1"	"0"	"133.5"	"195.1"	"544.8"	"163.0"	"172.8"	"139.5"	"675.7"	"113.1"	"196.3"	"116.7"	"96.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WVY7"	"Ubiquitin-like domain-containing CTD phosphatase 1 OS=Homo sapiens OX=9606 GN=UBLCP1 PE=1 SV=2"	"17"	"4"	"6"	"4"	"318"	"36.8"	"6.46"	"1119.65"	"9.46"	"3"	"3"	"protein metabolism;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00240, Pf03031"	"134510"	"ENSG00000164332"	"UBLCP1"	"D3DQJ7; hsa:134510; Q8WVY7; Q96DK5"	""	""	"0"	"0"	"127.9"	"132.3"	"509.1"	"173.2"	"136.4"	"102.3"	"740.8"	"77.5"	"140.5"	"86.0"	"78.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52701"	"DNA mismatch repair protein Msh6 OS=Homo sapiens OX=9606 GN=MSH6 PE=1 SV=2"	"3"	"4"	"7"	"4"	"1360"	"152.7"	"6.90"	"1236.38"	"9.45"	"4"	"3"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00488, Pf00855, Pf01624, Pf05188, Pf05190, Pf05192"	"2956"	"ENSG00000116062"	"MSH6"	"B4DF41; B4E3I4; F5H2F9; hsa:2956; O43706; O43917; P52701; Q8TCX4; Q9BTB5"	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Defective Mismatch Repair Associated With MSH2; Defective Mismatch Repair Associated With MSH6"	"Glioblastoma signaling pathways; Retinoblastoma gene in cancer; Chromosomal and microsatellite instability in colorectal cancer ; DNA repair pathways, full network; DNA mismatch repair"	"8"	"0"	"198.3"	"200.3"	"703.8"	"172.7"	"159.2"	"137.1"	"652.4"	"61.0"	"122.4"	"93.6"	"79.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13547"	"Histone deacetylase 1 OS=Homo sapiens OX=9606 GN=HDAC1 PE=1 SV=1"	"7"	"3"	"7"	"3"	"482"	"55.1"	"5.48"	"1531.52"	"9.45"	"3"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00850"	"3065"	"ENSG00000116478"	"HDAC1"	"hsa:3065; Q13547; Q92534"	"Factors involved in megakaryocyte development and platelet production; Formation of the beta-catenin:TCF transactivating complex; HDACs deacetylate histones; NoRC negatively regulates rRNA expression; Estrogen-dependent gene expression; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Potential therapeutics for SARS; SUMOylation of chromatin organization proteins; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes; SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Deactivation of the beta-catenin transactivating complex; Regulation of PTEN gene transcription; MECP2 regulates transcription of neuronal ligands; Downregulation of SMAD2/3:SMAD4 transcriptional activity; RNA Polymerase I Transcription Initiation; p75NTR negatively regulates cell cycle via SC1; NOTCH1 Intracellular Domain Regulates Transcription; Notch-HLH transcription pathway; Regulation of MECP2 expression and activity; STAT3 nuclear events downstream of ALK signaling; G1/S-Specific Transcription; Regulation of TP53 Activity through Acetylation; Transcription of E2F targets under negative control by DREAM complex; Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1; MECP2 regulates neuronal receptors and channels; Repression of WNT target genes; Loss of MECP2 binding ability to 5mC-DNA"	"Androgen receptor signaling pathway; Energy metabolism; Cell cycle; TNF-related weak inducer of apoptosis (TWEAK) signaling pathway; Neural crest differentiation; Retinoblastoma gene in cancer; Notch signaling; Apoptosis-related network due to altered Notch3 in ovarian cancer; Initiation of transcription and translation elongation at the HIV-1 LTR; MECP2 and associated Rett syndrome; IL6 signaling pathway; Valproic acid pathway; VEGFA-VEGFR2 signaling; Ethanol effects on histone modifications; Rett syndrome causing genes; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; Ciliary landscape; Transcription co-factors SKI and SKIL protein partners; Overlap between signal transduction pathways contributing to LMNA laminopathies; Opioid receptor pathways; Notch signaling pathway; Sudden infant death syndrome (SIDS) susceptibility pathways"	"53"	"0"	"373.1"	"409.4"	"1314.2"	"405.9"	"346.5"	"295.5"	"1444.1"	"173.7"	"321.1"	"259.7"	"257.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95218"	"Zinc finger Ran-binding domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ZRANB2 PE=1 SV=2"	"15"	"5"	"7"	"5"	"330"	"37.4"	"10.01"	"1438.22"	"9.43"	"4"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00641"	"9406"	"ENSG00000132485"	"ZRANB2"	"D3DQ75; hsa:9406; O95218; Q53GS3; Q59F92; Q5VV33; Q5VV34; Q8IXN6; Q9UP63"	""	""	"0"	"0"	"347.3"	"369.2"	"1339.0"	"383.4"	"354.7"	"284.7"	"1709.4"	"249.8"	"299.5"	"284.6"	"270.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P84101"	"Small EDRK-rich factor 2 OS=Homo sapiens OX=9606 GN=SERF2 PE=1 SV=1"	"29"	"3"	"7"	"3"	"59"	"6.9"	"10.45"	"1534.05"	"9.41"	"3"	"2"	"other biological processes"	"cytosol;nucleus"	""	"Pf04419"	"10169"	"ENSG00000140264"	"SERF2"	"A6NL45; B5MCG1; B9A026; hsa:10169; O75918; O88891; P84101; Q9BZH7"	""	""	"0"	"0"	"284.9"	"293.7"	"553.5"	"292.3"	"351.8"	"308.8"	"1721.8"	"676.1"	"1264.3"	"1084.2"	"1146.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15160"	"DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1"	"10"	"3"	"6"	"3"	"346"	"39.2"	"5.50"	"1192.73"	"9.39"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01000, Pf01193"	"9533"	"ENSG00000171453"	"POLR1C"	"hsa:9533; O15160; O75395; Q5JTE3"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"Pyrimidine metabolism; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"15"	"0"	"57.7"	"76.6"	"241.3"	"62.2"	"60.9"	"53.6"	"293.5"	"96.4"	"339.3"	"350.8"	"369.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09960"	"Leukotriene A-4 hydrolase OS=Homo sapiens OX=9606 GN=LTA4H PE=1 SV=2"	"7"	"3"	"5"	"3"	"611"	"69.2"	"6.18"	"1240.33"	"9.30"	"3"	"2"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf01433, Pf09127, Pf17900"	"4048"	"ENSG00000111144"	"LTA4H"	"B4DNQ9; F8VV40; hsa:4048; P09960; Q6IAT6; Q9UCT7"	"Neutrophil degranulation; Biosynthesis of protectins; Synthesis of Leukotrienes (LT) and Eoxins (EX); Biosynthesis of D-series resolvins; Biosynthesis of E-series 18(S)-resolvins; Biosynthesis of aspirin-triggered D-series resolvins; Biosynthesis of E-series 18(R)-resolvins"	"Eicosanoid metabolism via lipooxygenases (LOX); Prostaglandin and leukotriene metabolism in senescence ; Leukotriene metabolic pathway; Prostaglandin and leukotriene metabolism in senescence"	"11"	"0"	"143.5"	"181.9"	"977.5"	"186.8"	"163.5"	"115.6"	"1344.8"	"114.9"	"152.8"	"97.3"	"88.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16637"	"Survival motor neuron protein OS=Homo sapiens OX=9606 GN=SMN1 PE=1 SV=1"	"13"	"3"	"7"	"3"	"294"	"31.8"	"6.55"	"1303.86"	"9.28"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06003"	"6606; 6607"	"ENSG00000172062; ENSG00000205571; ENSG00000273772; ENSG00000275349; ENSG00000277773"	"SMN1; SMN2"	"A8K0V4; hsa:6606; hsa:6607; Q13119; Q16637; Q549U5; Q96J51"	"snRNP Assembly; SARS-CoV-2 modulates host translation machinery"	"11p11.2 copy number variation syndrome"	"3"	"0"	"211.9"	"222.1"	"689.2"	"191.9"	"185.9"	"155.5"	"790.7"	"77.1"	"132.5"	"89.3"	"93.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09497"	"Clathrin light chain B OS=Homo sapiens OX=9606 GN=CLTB PE=1 SV=1"	"12"	"3"	"6"	"3"	"229"	"25.2"	"4.64"	"1132.96"	"9.23"	"3"	"3"	"transport"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf01086"	"1212"	"ENSG00000175416"	"CLTB"	"hsa:1212; P09497; Q53Y37; Q6FHW1"	"Lysosome Vesicle Biogenesis; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; Formation of annular gap junctions"	"Ebola virus infection in host; Fragile X syndrome"	"10"	"0"	"219.8"	"219.5"	"604.3"	"228.8"	"197.1"	"156.1"	"701.7"	"117.8"	"196.7"	"146.0"	"146.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5T653"	"39S ribosomal protein L2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL2 PE=1 SV=2"	"15"	"3"	"4"	"3"	"305"	"33.3"	"11.30"	"858.80"	"9.23"	"2"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf00181, Pf03947"	"51069"	"ENSG00000112651"	"MRPL2"	"B2RC56; hsa:51069; Q5T653; Q8WUL1; Q96Q56; Q9Y311"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"111.3"	"100.9"	"290.6"	"107.5"	"101.2"	"83.0"	"341.0"	"60.2"	"88.0"	"75.6"	"89.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94788"	"Retinal dehydrogenase 2 OS=Homo sapiens OX=9606 GN=ALDH1A2 PE=1 SV=3"	"4"	"2"	"4"	"1"	"518"	"56.7"	"6.05"	"820.89"	"9.18"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00171"	"8854"	"ENSG00000128918"	"ALDH1A2"	"B3KY52; B4DZR2; F5H2Y9; H0YM00; hsa:8854; O94788; Q2PJS6; Q8NHQ4; Q9UBR8; Q9UFY0"	"RA biosynthesis pathway"	"Ethanol effects on histone modifications; 22q11.2 copy number variation syndrome; Markers of kidney cell lineage; Vitamin A and carotenoid metabolism"	"5"	"0"	"11.6"	"14.0"	"80.8"	"12.3"	"19.2"	"11.2"	"125.1"	"8.7"	"14.5"	"12.4"	"6.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92804"	"TATA-binding protein-associated factor 2N OS=Homo sapiens OX=9606 GN=TAF15 PE=1 SV=1"	"5"	"3"	"7"	"1"	"592"	"61.8"	"8.02"	"1160.64"	"9.18"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00641"	"8148"	"ENSG00000270647; ENSG00000276833"	"TAF15"	"B2R837; hsa:8148; Q86X94; Q92751; Q92804"	"Regulation of TP53 Activity through Phosphorylation; RNA Polymerase II Pre-transcription Events; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation"	"17q12 copy number variation syndrome"	"10"	"0"	"46.8"	"52.9"	"186.8"	"66.5"	"57.1"	"50.8"	"193.9"	"26.0"	"64.7"	"44.5"	"40.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7L5N1"	"COP9 signalosome complex subunit 6 OS=Homo sapiens OX=9606 GN=COPS6 PE=1 SV=1"	"9"	"2"	"4"	"2"	"327"	"36.1"	"5.73"	"1024.18"	"9.18"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf01398, Pf13012"	"10980"	"ENSG00000168090"	"COPS6"	"A4D2A3; hsa:10980; O15387; Q7L5N1"	"Neddylation; Formation of TC-NER Pre-Incision Complex; DNA Damage Recognition in GG-NER; Cargo recognition for clathrin-mediated endocytosis"	"Nucleotide-binding oligomerization domain (NOD) pathway; Ciliary landscape"	"6"	"0"	"151.7"	"188.3"	"689.2"	"185.3"	"183.8"	"142.7"	"723.5"	"91.3"	"148.9"	"104.8"	"117.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5T4S7"	"E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens OX=9606 GN=UBR4 PE=1 SV=1"	"1"	"4"	"6"	"4"	"5183"	"573.5"	"6.04"	"870.37"	"9.13"	"3"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus"	"other molecular function"	"Pf02207, Pf13764, Pf19423"	"23352"	"ENSG00000127481"	"UBR4"	"A8MPT2; A8MQ33; A8MQB1; hsa:23352; O60646; O75050; Q4QRK5; Q5T4S7; Q5T4S8; Q5T4S9; Q5TBN8; Q5TBP2; Q6DKH8; Q6P4A4; Q7L8P7; Q8IXJ4; Q8TDN5; Q8WV67; Q9HA46; Q9P2N9; Q9UG82"	"Antigen processing: Ubiquitination & Proteasome degradation; Neutrophil degranulation"	""	"2"	"0"	"76.8"	"74.3"	"256.0"	"75.4"	"67.4"	"56.5"	"258.7"	"37.3"	"56.5"	"54.5"	"47.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62995"	"Transformer-2 protein homolog beta OS=Homo sapiens OX=9606 GN=TRA2B PE=1 SV=1"	"11"	"3"	"6"	"3"	"288"	"33.6"	"11.25"	"968.57"	"9.12"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6434"	"ENSG00000136527"	"TRA2B"	"B4DVK2; D3DNU3; hsa:6434; O15449; P62995; Q15815; Q64283"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle"	"mRNA processing"	"5"	"0"	"238.3"	"276.9"	"966.2"	"186.2"	"218.9"	"147.0"	"1224.3"	"116.4"	"173.2"	"114.7"	"105.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16822"	"Phosphoenolpyruvate carboxykinase [GTP], mitochondrial OS=Homo sapiens OX=9606 GN=PCK2 PE=1 SV=4"	"5"	"3"	"5"	"3"	"640"	"70.7"	"7.62"	"773.92"	"9.11"	"2"	"3"	"other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf00821, Pf17297"	"5106"	"ENSG00000100889; ENSG00000285241"	"PCK2"	"B4DW73; hsa:5106; O43253; Q16822; Q86U01; Q9BV62"	"Gluconeogenesis"	"Adipogenesis; Transcription factor regulation in adipogenesis; PPAR signaling pathway; PI3K-Akt signaling pathway; Krebs cycle disorders; DNA damage response (only ATM dependent)"	"7"	"0"	"91.5"	"106.6"	"551.3"	"101.8"	"82.9"	"59.2"	"818.4"	"66.2"	"81.3"	"79.2"	"68.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94905"	"Erlin-2 OS=Homo sapiens OX=9606 GN=ERLIN2 PE=1 SV=1"	"13"	"4"	"7"	"4"	"339"	"37.8"	"5.62"	"1456.47"	"9.11"	"4"	"3"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf01145"	"11160"	"ENSG00000147475"	"ERLIN2"	"A0JLQ1; A8K5S9; B4DM38; D3DSW0; hsa:11160; O94905; Q6NW21; Q86VS6; Q86W49"	"ABC-family proteins mediated transport; Defective CFTR causes cystic fibrosis; Signaling by FGFR1 in disease; Signaling by plasma membrane FGFR1 fusions"	""	"4"	"0"	"355.7"	"387.4"	"1265.0"	"323.8"	"284.6"	"235.4"	"1337.1"	"129.6"	"225.6"	"188.3"	"182.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82675"	"28S ribosomal protein S5, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS5 PE=1 SV=2"	"9"	"3"	"5"	"3"	"430"	"48.0"	"9.92"	"684.14"	"9.10"	"2"	"3"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00333, Pf03719"	"64969"	"ENSG00000144029"	"MRPS5"	"hsa:64969; P82675; Q4ZFY5; Q96LJ6; Q9BWI4; Q9BYC4"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"86.0"	"78.8"	"219.9"	"83.0"	"81.9"	"74.4"	"240.7"	"36.7"	"43.4"	"52.9"	"42.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22087"	"rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2"	"10"	"2"	"4"	"2"	"321"	"33.8"	"10.18"	"853.24"	"9.07"	"2"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf01269"	"2091"	"ENSG00000105202; ENSG00000280548"	"FBL"	"B5BUE8; hsa:2091; O75259; P22087; Q6IAT5; Q9UPI6"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	"52.6"	"61.6"	"240.3"	"60.0"	"61.6"	"38.0"	"274.2"	"29.1"	"63.8"	"43.7"	"36.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82930"	"28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2"	"11"	"3"	"7"	"3"	"218"	"25.6"	"9.98"	"1432.98"	"9.00"	"3"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf16053"	"65993"	"ENSG00000074071"	"MRPS34"	"hsa:65993; P82930; Q9BVI7"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"259.3"	"336.6"	"991.4"	"308.3"	"254.7"	"259.3"	"1158.6"	"152.0"	"185.1"	"179.2"	"169.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UPN9"	"E3 ubiquitin-protein ligase TRIM33 OS=Homo sapiens OX=9606 GN=TRIM33 PE=1 SV=3"	"3"	"3"	"5"	"3"	"1127"	"122.5"	"6.67"	"620.29"	"9.00"	"2"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00439, Pf00628, Pf00643, Pf13445"	"51592"	"ENSG00000197323"	"TRIM33"	"hsa:51592; O95855; Q5TG72; Q5TG73; Q5TG74; Q9C017; Q9UJ79; Q9UPN9"	"Downregulation of SMAD2/3:SMAD4 transcriptional activity; Germ layer formation at gastrulation"	"Ectoderm differentiation"	"3"	"0"	"49.0"	"61.0"	"203.6"	"59.2"	"60.7"	"45.9"	"266.6"	"48.0"	"70.9"	"51.5"	"57.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UHB9"	"Signal recognition particle subunit SRP68 OS=Homo sapiens OX=9606 GN=SRP68 PE=1 SV=2"	"7"	"4"	"7"	"4"	"627"	"70.7"	"8.56"	"1488.16"	"8.99"	"4"	"3"	"transport;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf16969"	"6730"	"ENSG00000167881"	"SRP68"	"B3KUU5; B3KWY7; G3V1U4; hsa:6730; Q8NCJ4; Q8WUK2; Q9UHB9"	"SRP-dependent cotranslational protein targeting to membrane"	""	"1"	"0"	"155.2"	"158.2"	"644.4"	"145.0"	"151.1"	"91.9"	"700.1"	"75.4"	"129.4"	"91.0"	"102.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99757"	"Thioredoxin, mitochondrial OS=Homo sapiens OX=9606 GN=TXN2 PE=1 SV=2"	"9"	"1"	"4"	"1"	"166"	"18.4"	"8.29"	"1223.58"	"8.99"	"1"	"1"	"stress response;other biological processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00085"	"25828"	"ENSG00000100348"	"TXN2"	"hsa:25828; Q5JZA0; Q6FH60; Q99757; Q9UH29"	"Detoxification of Reactive Oxygen Species; Degradation of cysteine and homocysteine"	"Oxidative stress response"	"3"	"0"	"145.5"	"161.8"	"843.9"	"209.0"	"151.6"	"102.7"	"1229.3"	"101.1"	"165.2"	"101.0"	"70.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3Z3"	"Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 OS=Homo sapiens OX=9606 GN=SAMHD1 PE=1 SV=2"	"9"	"4"	"7"	"4"	"626"	"72.2"	"7.14"	"1158.55"	"8.98"	"3"	"4"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01966, Pf07647"	"25939"	"ENSG00000101347"	"SAMHD1"	"B4E2A5; E1P5V2; hsa:25939; Q5JXG8; Q8N491; Q9H004; Q9H005; Q9H3U9; Q9Y3Z3"	"Interferon alpha/beta signaling; Nucleotide catabolism"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P00390"	"Glutathione reductase, mitochondrial OS=Homo sapiens OX=9606 GN=GSR PE=1 SV=2"	"7"	"3"	"6"	"3"	"522"	"56.2"	"8.50"	"989.83"	"8.98"	"3"	"3"	"other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion"	"other molecular function"	"Pf00070, Pf02852"	"2936"	"ENSG00000104687"	"GSR"	"C8KIL8; C8KIL9; C8KIM0; D3DSV3; hsa:2936; P00390; Q7Z5C9; Q9NP63"	""	"Glutathione metabolism; Selenium micronutrient network; Trans-sulfuration, one-carbon metabolism and related pathways; Nuclear receptors meta-pathway; NRF2 pathway; Amino acid metabolism; Oxidative stress response; Vitamin D-sensitive calcium signaling in depression; Sulfation biotransformation reaction; Metapathway biotransformation Phase I and II"	"10"	"0"	"65.4"	"98.2"	"377.8"	"92.7"	"76.5"	"64.2"	"417.4"	"66.5"	"89.4"	"76.7"	"80.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92820"	"Gamma-glutamyl hydrolase OS=Homo sapiens OX=9606 GN=GGH PE=1 SV=2"	"15"	"4"	"7"	"4"	"318"	"35.9"	"7.11"	"1498.93"	"8.96"	"4"	"3"	"other metabolic processes"	"non-structural extracellular;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf07722"	"8836"	"ENSG00000137563"	"GGH"	"hsa:8836; Q92820"	"Neutrophil degranulation"	"Fluoropyrimidine activity"	"2"	"0"	"217.3"	"138.8"	"476.1"	"166.8"	"123.7"	"108.4"	"745.2"	"270.2"	"867.9"	"1382.2"	"1888.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P48556"	"26S proteasome non-ATPase regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMD8 PE=1 SV=2"	"9"	"3"	"6"	"3"	"350"	"39.6"	"9.70"	"955.90"	"8.91"	"3"	"3"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf10075"	"5714"	"ENSG00000099341"	"PSMD8"	"B4DX18; hsa:5714; P48556; Q6P1L7"	"Regulation of expression of SLITs and ROBOs; Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; SCF(Skp2)-mediated degradation of p27/p21; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Ciliary landscape; Alzheimer's disease"	"64"	"0"	"278.3"	"288.0"	"904.2"	"256.0"	"242.9"	"195.4"	"770.7"	"113.9"	"156.0"	"132.5"	"139.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9C0C2"	"182 kDa tankyrase-1-binding protein OS=Homo sapiens OX=9606 GN=TNKS1BP1 PE=1 SV=4"	"3"	"4"	"6"	"4"	"1729"	"181.7"	"4.86"	"909.69"	"8.90"	"3"	"3"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf15327"	"85456"	"ENSG00000149115"	"TNKS1BP1"	"A7E2F8; hsa:85456; Q6PJ35; Q6ZV74; Q9C0C2"	"Deadenylation of mRNA; TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"	"Ciliary landscape"	"3"	"0"	"56.2"	"65.4"	"199.1"	"51.6"	"53.5"	"43.4"	"217.6"	"36.5"	"67.4"	"63.2"	"59.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BX68"	"Histidine triad nucleotide-binding protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=HINT2 PE=1 SV=1"	"21"	"2"	"4"	"2"	"163"	"17.2"	"9.16"	"1006.09"	"8.90"	"2"	"2"	"other metabolic processes;other biological processes"	"other membranes;mitochondrion;other cell component"	"other molecular function"	"Pf01230"	"84681"	"ENSG00000137133"	"HINT2"	"hsa:84681; Q5TCW3; Q9BX68"	"RHOD GTPase cycle"	""	"1"	"0"	"38.1"	"35.2"	"210.1"	"45.0"	"37.1"	"31.1"	"241.2"	"21.1"	"23.4"	"20.7"	"20.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75832"	"26S proteasome non-ATPase regulatory subunit 10 OS=Homo sapiens OX=9606 GN=PSMD10 PE=1 SV=1"	"11"	"4"	"8"	"4"	"226"	"24.4"	"6.10"	"1207.34"	"8.89"	"4"	"4"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf12796"	"5716"	"ENSG00000101843"	"PSMD10"	"hsa:5716; O75832; Q5U0B2; Q8IZK9"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Parkin-ubiquitin proteasomal system pathway"	"61"	"0"	"288.7"	"328.5"	"1653.1"	"325.0"	"273.1"	"254.5"	"2301.4"	"212.0"	"218.0"	"260.6"	"141.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75131"	"Copine-3 OS=Homo sapiens OX=9606 GN=CPNE3 PE=1 SV=1"	"4"	"1"	"2"	"1"	"537"	"60.1"	"5.85"	""	"8.89"	""	"1"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;kinase activity;other molecular function"	"Pf00168, Pf07002"	"8895"	"ENSG00000085719"	"CPNE3"	"A8KA47; hsa:8895; O75131; Q8IYA1"	"Neutrophil degranulation; Glycerophospholipid biosynthesis"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43795"	"Unconventional myosin-Ib OS=Homo sapiens OX=9606 GN=MYO1B PE=1 SV=3"	"2"	"2"	"6"	"1"	"1136"	"131.9"	"9.38"	"1065.81"	"8.85"	"2"	"2"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00063, Pf00612, Pf06017"	"4430"	"ENSG00000128641"	"MYO1B"	"hsa:4430; O43794; O43795; Q7Z6L5"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"n/a"	"n/a"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UGP8"	"Translocation protein SEC63 homolog OS=Homo sapiens OX=9606 GN=SEC63 PE=1 SV=2"	"5"	"3"	"5"	"3"	"760"	"87.9"	"5.31"	"1321.92"	"8.85"	"3"	"2"	"other metabolic processes;transport;developmental processes"	"other membranes;ER/Golgi"	"transporter activity;other molecular function"	"Pf00226, Pf02889"	"11231"	"ENSG00000025796"	"SEC63"	"hsa:11231; O95380; Q5THN4; Q86VS9; Q8IWL0; Q9NTE0; Q9UGP8"	""	""	"0"	"0"	"181.1"	"197.9"	"764.8"	"160.9"	"148.3"	"118.5"	"592.4"	"65.6"	"120.0"	"74.7"	"77.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46379"	"Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2"	"5"	"4"	"7"	"4"	"1132"	"119.3"	"5.60"	"1209.58"	"8.84"	"4"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;other membranes;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;translation activity;other molecular function"	"Pf00240, Pf12057"	"7917"	"ENSG00000096155; ENSG00000204463; ENSG00000227761; ENSG00000228760; ENSG00000229524; ENSG00000233348; ENSG00000234651"	"BAG6"	"A2ADJ7; A3KQ42; A3KQ44; A6NGY6; A6PWF7; B0UX84; B4DZ12; B4E3V4; E7EMZ4; F8VXY4; hsa:7917; O95874; P46379; Q5HYL9; Q5SQ35; Q5SQ36; Q5SQ37; Q5SQ41; Q5SRP8; Q5SRP9; Q5STC1; Q5STX1; Q5STX3; Q96SA6; Q9BCN4"	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"	""	"1"	"0"	"69.2"	"64.0"	"225.9"	"62.3"	"67.1"	"50.0"	"257.7"	"36.8"	"48.6"	"52.5"	"62.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43813"	"Glutathione S-transferase LANCL1 OS=Homo sapiens OX=9606 GN=LANCL1 PE=1 SV=1"	"9"	"3"	"6"	"3"	"399"	"45.3"	"7.75"	"1143.87"	"8.83"	"3"	"3"	"other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf05147"	"10314"	"ENSG00000115365"	"LANCL1"	"hsa:10314; O43813"	""	""	"0"	"0"	"152.7"	"152.6"	"431.3"	"177.9"	"148.6"	"119.8"	"538.8"	"145.6"	"216.8"	"163.7"	"206.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NBJ5"	"Procollagen galactosyltransferase 1 OS=Homo sapiens OX=9606 GN=COLGALT1 PE=1 SV=1"	"5"	"2"	"4"	"2"	"622"	"71.6"	"7.31"	"920.75"	"8.82"	"2"	"2"	"cell organization and biogenesis;other biological processes"	"ER/Golgi"	"other molecular function"	"Pf01755, Pf13704"	"79709"	"ENSG00000130309"	"COLGALT1"	"hsa:79709; Q8NBJ5; Q8NC64"	"Collagen biosynthesis and modifying enzymes"	"Type I collagen synthesis in the context of osteogenesis imperfecta"	"2"	"0"	"13.6"	"19.7"	"70.3"	"14.6"	"20.9"	"9.2"	"101.9"	"16.2"	"23.4"	"19.9"	"22.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14136"	"Glial fibrillary acidic protein OS=Homo sapiens OX=9606 GN=GFAP PE=1 SV=1"	"6"	"2"	"5"	"1"	"432"	"49.9"	"5.52"	"723.05"	"8.77"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00038, Pf04732"	"2670"	"ENSG00000131095"	"GFAP"	"A7REI1; B2RD44; D3DX59; E9PAX3; hsa:2670; P14136; Q53H98; Q5D055; Q6ZQS3; Q7Z5J6; Q7Z5J7; Q96KS4; Q96P18; Q9UFD0"	"Nuclear signaling by ERBB4; Chaperone Mediated Autophagy"	"Neural crest differentiation; Spinal cord injury; Neuroinflammation and glutamatergic signaling"	"5"	"0"	"5.9"	"29.9"	"51.1"	"19.1"	"30.3"	"13.4"	"28.9"	"4.1"	"7.0"	"3.7"	"11.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q06203"	"Amidophosphoribosyltransferase OS=Homo sapiens OX=9606 GN=PPAT PE=1 SV=1"	"8"	"4"	"6"	"4"	"517"	"57.4"	"6.76"	"1146.06"	"8.77"	"3"	"3"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf00156, Pf13522"	"5471"	"ENSG00000128059"	"PPAT"	"hsa:5471; Q06203"	"Purine ribonucleoside monophosphate biosynthesis"	"Fluoropyrimidine activity; Metabolic reprogramming in colon cancer"	"3"	"0"	"206.4"	"280.5"	"842.0"	"255.8"	"246.0"	"180.1"	"1413.0"	"176.5"	"244.4"	"183.1"	"183.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16629"	"Serine/arginine-rich splicing factor 7 OS=Homo sapiens OX=9606 GN=SRSF7 PE=1 SV=1"	"19"	"3"	"4"	"3"	"238"	"27.4"	"11.82"	"331.76"	"8.76"	"1"	"3"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6432"	"ENSG00000115875"	"SRSF7"	"B4DLU6; G5E9M3; hsa:6432; Q16629; Q564D3"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; mRNA Splicing - Minor Pathway"	"mRNA processing"	"7"	"0"	"261.3"	"264.6"	"883.7"	"179.9"	"201.4"	"140.9"	"1002.3"	"111.7"	"157.4"	"106.1"	"107.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49721"	"Proteasome subunit beta type-2 OS=Homo sapiens OX=9606 GN=PSMB2 PE=1 SV=1"	"14"	"3"	"4"	"3"	"201"	"22.8"	"7.02"	"544.39"	"8.75"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf00227"	"5690"	"ENSG00000126067"	"PSMB2"	"D3DPS0; hsa:5690; P31145; P49721; Q9BWZ9"	"ABC-family proteins mediated transport; Orc1 removal from chromatin; Assembly of the pre-replicative complex; Separation of Sister Chromatids; Regulation of expression of SLITs and ROBOs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"62"	"0"	"175.3"	"230.2"	"807.0"	"212.9"	"178.2"	"135.6"	"670.5"	"166.2"	"186.4"	"192.0"	"238.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43488"	"Aflatoxin B1 aldehyde reductase member 2 OS=Homo sapiens OX=9606 GN=AKR7A2 PE=1 SV=3"	"11"	"4"	"6"	"4"	"359"	"39.6"	"7.17"	"1092.32"	"8.73"	"3"	"3"	"other metabolic processes"	"cytosol;mitochondrion;ER/Golgi;other cell component"	"other molecular function"	"Pf00248"	"8574"	"ENSG00000053371"	"AKR7A2"	"hsa:8574; O43488; O75749; Q5TG63"	"Aflatoxin activation and detoxification"	"Aflatoxin B1 metabolism; Metapathway biotransformation Phase I and II"	"3"	"0"	"385.4"	"482.1"	"1296.8"	"408.3"	"472.6"	"426.1"	"1558.5"	"289.7"	"478.7"	"329.5"	"304.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6UX04"	"Spliceosome-associated protein CWC27 homolog OS=Homo sapiens OX=9606 GN=CWC27 PE=1 SV=1"	"7"	"2"	"4"	"2"	"472"	"53.8"	"5.80"	"896.07"	"8.72"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	"Pf00160"	"10283"	"ENSG00000153015"	"CWC27"	"hsa:10283; O60529; O60530; Q6UX04; Q96EM3"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"54.5"	"56.1"	"156.2"	"55.4"	"63.6"	"50.7"	"167.0"	"39.0"	"59.7"	"53.2"	"44.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NZJ9"	"Diphosphoinositol polyphosphate phosphohydrolase 2 OS=Homo sapiens OX=9606 GN=NUDT4 PE=1 SV=2"	"14"	"3"	"4"	"2"	"180"	"20.3"	"6.35"	"464.13"	"8.72"	"1"	"3"	"other metabolic processes;signal transduction"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00293"	"11163"	"ENSG00000173598"	"NUDT4"	"B7Z916; hsa:11163; Q4AEJ6; Q53EZ2; Q68DD7; Q9NPC5; Q9NS30; Q9NZJ9; Q9NZK0; Q9NZK1"	"Synthesis of pyrophosphates in the cytosol"	""	"1"	"1"	"62.9"	"84.3"	"360.3"	"118.5"	"173.3"	"293.9"	"1330.0"	"786.6"	"1939.6"	"1784.6"	"2307.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P28074"	"Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3"	"13"	"3"	"6"	"3"	"263"	"28.5"	"6.92"	"1159.68"	"8.71"	"3"	"3"	"protein metabolism;other metabolic processes;stress response"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00227"	"5693"	"ENSG00000100804"	"PSMB5"	"B2R4N9; B4DUM9; D3DS43; E9PAV2; hsa:5693; P28074; Q16242; Q6PEW2; Q7Z3B5; Q86T01; Q9TNN9"	"Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; UCH proteinases; Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of expression of SLITs and ROBOs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"62"	"0"	"117.2"	"124.8"	"450.1"	"134.9"	"111.2"	"96.9"	"388.5"	"111.3"	"260.6"	"314.7"	"374.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75822"	"Eukaryotic translation initiation factor 3 subunit J OS=Homo sapiens OX=9606 GN=EIF3J PE=1 SV=2"	"20"	"5"	"9"	"5"	"258"	"29.0"	"4.83"	"2469.92"	"8.70"	"5"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf08597"	"8669"	"ENSG00000104131"	"EIF3J"	"B4DUI3; F5H425; hsa:8669; O75822; Q9BUD2; Q9H8Q2; Q9UI65"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"8"	"0"	"661.5"	"636.7"	"1762.3"	"646.1"	"622.8"	"530.2"	"1893.3"	"257.2"	"454.3"	"390.8"	"401.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y295"	"Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1"	"10"	"3"	"5"	"3"	"367"	"40.5"	"8.90"	"770.22"	"8.70"	"2"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01926, Pf02824, Pf16897"	"4733"	"ENSG00000185721"	"DRG1"	"B2RDS8; hsa:4733; Q6FGP8; Q8WW69; Q9UGF2; Q9Y295"	""	""	"0"	"0"	"205.7"	"209.1"	"588.5"	"197.0"	"164.9"	"144.1"	"415.8"	"69.6"	"95.9"	"98.6"	"110.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BYD1"	"39S ribosomal protein L13, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL13 PE=1 SV=1"	"17"	"2"	"4"	"2"	"178"	"20.7"	"9.16"	"1057.28"	"8.69"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00572"	"28998"	"ENSG00000172172"	"MRPL13"	"B2R4R8; hsa:28998; Q9BYD1; Q9UI04"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"65.1"	"77.0"	"212.9"	"66.7"	"79.2"	"50.8"	"300.3"	"50.1"	"72.0"	"46.8"	"53.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y333"	"U6 snRNA-associated Sm-like protein LSm2 OS=Homo sapiens OX=9606 GN=LSM2 PE=1 SV=1"	"29"	"2"	"4"	"2"	"95"	"10.8"	"6.52"	"972.99"	"8.68"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01423"	"57819"	"ENSG00000172850; ENSG00000204392; ENSG00000224979; ENSG00000225998; ENSG00000231502; ENSG00000236826"	"LSM2"	"hsa:57819; Q6FGG1; Q9Y333"	"mRNA Splicing - Major Pathway; mRNA decay by 5' to 3' exoribonuclease"	"mRNA processing"	"3"	"0"	"100.6"	"155.6"	"676.6"	"132.8"	"120.5"	"86.7"	"871.3"	"94.4"	"141.0"	"76.3"	"94.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01433"	"AMP deaminase 2 OS=Homo sapiens OX=9606 GN=AMPD2 PE=1 SV=2"	"3"	"3"	"6"	"3"	"879"	"100.6"	"6.93"	"805.28"	"8.68"	"3"	"3"	"other metabolic processes;other biological processes"	"cytosol"	"other molecular function"	"Pf19326"	"271"	"ENSG00000116337"	"AMPD2"	"B4DK50; B4DZI5; E9PNG0; hsa:271; Q01433; Q14856; Q14857; Q16686; Q16687; Q16688; Q16729; Q5T693; Q5T695; Q96IA1; Q9UDX8; Q9UDX9; Q9UMU4"	"Purine salvage"	""	"1"	"0"	"142.2"	"117.3"	"382.5"	"121.0"	"111.3"	"99.8"	"408.3"	"98.4"	"503.3"	"563.8"	"441.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H1E3"	"Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 OS=Homo sapiens OX=9606 GN=NUCKS1 PE=1 SV=1"	"11"	"2"	"6"	"2"	"243"	"27.3"	"5.08"	"1068.00"	"8.65"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	""	"64710"	"ENSG00000069275"	"NUCKS1"	"hsa:64710; Q54AC0; Q5PXE7; Q9H1D6; Q9H1E3; Q9H723"	""	""	"0"	"0"	"182.5"	"219.7"	"643.1"	"196.7"	"191.7"	"176.8"	"822.8"	"157.6"	"190.1"	"140.4"	"117.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35269"	"General transcription factor IIF subunit 1 OS=Homo sapiens OX=9606 GN=GTF2F1 PE=1 SV=2"	"6"	"2"	"4"	"2"	"517"	"58.2"	"7.49"	"819.05"	"8.65"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf05793"	"2962"	"ENSG00000125651"	"GTF2F1"	"B2RCS0; hsa:2962; P35269; Q9BWN0"	"TP53 Regulates Transcription of DNA Repair Genes; mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA; Viral Messenger RNA Synthesis; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Estrogen-dependent gene expression; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Signaling by FGFR2 IIIa TM"	""	"32"	"0"	"100.5"	"129.6"	"360.0"	"100.8"	"107.5"	"104.5"	"393.4"	"75.9"	"91.6"	"82.2"	"104.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P43034"	"Platelet-activating factor acetylhydrolase IB subunit alpha OS=Homo sapiens OX=9606 GN=PAFAH1B1 PE=1 SV=2"	"10"	"3"	"4"	"2"	"410"	"46.6"	"7.37"	"536.84"	"8.65"	"2"	"2"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400, Pf08513"	"5048"	"ENSG00000007168"	"PAFAH1B1"	"B2R7Q7; hsa:5048; P43034; Q8WZ88; Q8WZ89"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; RHO GTPases Activate Formins; COPI-independent Golgi-to-ER retrograde traffic; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"Wnt signaling pathway and pluripotency; Ciliary landscape; Neurogenesis regulation in the olfactory epithelium"	"17"	"0"	"77.9"	"71.1"	"343.6"	"71.9"	"65.0"	"48.7"	"380.4"	"44.1"	"65.5"	"56.3"	"59.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14257"	"Reticulocalbin-2 OS=Homo sapiens OX=9606 GN=RCN2 PE=1 SV=1"	"10"	"3"	"6"	"3"	"317"	"36.9"	"4.40"	"793.47"	"8.63"	"3"	"3"	""	"ER/Golgi;nucleus"	"other molecular function"	"Pf13202"	"5955"	"ENSG00000117906"	"RCN2"	"A8MTG6; F8WCY5; hsa:5955; Q14257; Q53XN8"	""	""	"0"	"0"	"146.9"	"126.5"	"557.9"	"117.1"	"102.2"	"74.4"	"549.7"	"39.1"	"68.5"	"48.0"	"48.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3C6"	"Peptidyl-prolyl cis-trans isomerase-like 1 OS=Homo sapiens OX=9606 GN=PPIL1 PE=1 SV=1"	"25"	"3"	"6"	"3"	"166"	"18.2"	"7.99"	"1195.09"	"8.62"	"3"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00160"	"51645"	"ENSG00000137168"	"PPIL1"	"hsa:51645; O15001; Q5TDC9; Q9Y3C6"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"91.9"	"106.0"	"478.0"	"99.4"	"109.9"	"67.4"	"636.2"	"64.9"	"111.3"	"72.8"	"70.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P21266"	"Glutathione S-transferase Mu 3 OS=Homo sapiens OX=9606 GN=GSTM3 PE=1 SV=3"	"14"	"2"	"4"	"2"	"225"	"26.5"	"5.54"	"923.14"	"8.60"	"2"	"2"	"other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00043, Pf02798"	"2947"	"ENSG00000134202"	"GSTM3"	"hsa:2947; O60550; P21266; Q96HA3"	"Glutathione conjugation"	"Nuclear receptors meta-pathway; NRF2 pathway; Exercise-induced circadian regulation; Metapathway biotransformation Phase I and II"	"5"	"0"	"28.9"	"35.6"	"152.3"	"48.6"	"40.8"	"28.3"	"197.9"	"30.3"	"40.7"	"29.7"	"22.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P40222"	"Alpha-taxilin OS=Homo sapiens OX=9606 GN=TXLNA PE=1 SV=3"	"6"	"2"	"4"	"2"	"546"	"61.9"	"6.52"	"978.65"	"8.58"	"2"	"2"	"transport;other biological processes"	"non-structural extracellular;cytosol;other cell component"	"other molecular function"	"Pf09728"	"200081"	"ENSG00000084652"	"TXLNA"	"D3DPP6; hsa:200081; P40222; Q5TFJ6; Q66K62; Q86T54; Q86T85; Q86T86; Q86Y86; Q86YW3; Q8N2Y3"	"Other interleukin signaling"	""	"1"	"0"	"19.9"	"13.7"	"44.7"	"17.0"	"16.8"	"12.2"	"40.9"	"8.5"	"15.8"	"15.0"	"17.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15738"	"Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating OS=Homo sapiens OX=9606 GN=NSDHL PE=1 SV=2"	"8"	"2"	"3"	"2"	"373"	"41.9"	"8.06"	"267.79"	"8.58"	"1"	"2"	"other metabolic processes;developmental processes;signal transduction;other biological processes"	"other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf01073"	"50814"	"ENSG00000147383"	"NSDHL"	"D3DWT6; hsa:50814; O00344; Q15738"	"Cholesterol biosynthesis"	"Cholesterol biosynthesis pathway; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Cholesterol biosynthesis with skeletal dysplasias; Cholesterol metabolism; Cholesterol biosynthesis pathway in hepatocytes; Enterocyte cholesterol metabolism"	"7"	"0"	"107.8"	"116.1"	"396.8"	"106.1"	"84.5"	"68.3"	"476.5"	"55.7"	"78.7"	"68.7"	"63.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35250"	"Replication factor C subunit 2 OS=Homo sapiens OX=9606 GN=RFC2 PE=1 SV=3"	"10"	"2"	"4"	"2"	"354"	"39.1"	"6.44"	"875.80"	"8.58"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00004, Pf08542"	"5982"	"ENSG00000049541"	"RFC2"	"B5BU07; D3DXG3; hsa:5982; P32846; P35250; Q9BU93"	"Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; HDR through Homologous Recombination (HRR); HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Termination of translesion DNA synthesis; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Polymerase switching on the C-strand of the telomere; Polymerase switching; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER; Activation of ATR in response to replication stress"	"DNA replication; Nucleotide excision repair; 7q11.23 copy number variation syndrome; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"27"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15369"	"Elongin-C OS=Homo sapiens OX=9606 GN=ELOC PE=1 SV=1"	"29"	"2"	"4"	"2"	"112"	"12.5"	"4.78"	"794.47"	"8.56"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf03931"	"6921"	"ENSG00000154582"	"ELOC"	"E5RGD9; hsa:6921; Q15369; Q567Q6"	"Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; Antigen processing: Ubiquitination & Proteasome degradation; Regulation of expression of SLITs and ROBOs; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Vif-mediated degradation of APOBEC3G; Neddylation; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; Inactivation of CSF3 (G-CSF) signaling"	"Dual hijack model of Vif in HIV infection; VEGFA-VEGFR2 signaling; Type 2 papillary renal cell carcinoma; Hijack of ubiquitination by SARS-CoV-2; 11p11.2 copy number variation syndrome"	"22"	"0"	"63.3"	"95.2"	"146.9"	"52.4"	"55.4"	"39.9"	"195.8"	"69.5"	"75.3"	"60.5"	"81.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75792"	"Ribonuclease H2 subunit A OS=Homo sapiens OX=9606 GN=RNASEH2A PE=1 SV=2"	"12"	"3"	"5"	"3"	"299"	"33.4"	"5.25"	"642.98"	"8.55"	"2"	"3"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01351"	"10535"	"ENSG00000104889"	"RNASEH2A"	"B2RCY1; hsa:10535; O75792; Q96F11"	""	""	"0"	"0"	"115.2"	"115.5"	"425.2"	"136.0"	"135.7"	"96.5"	"464.6"	"77.3"	"117.9"	"97.4"	"95.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09661"	"U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2"	"20"	"4"	"7"	"4"	"255"	"28.4"	"8.62"	"1365.23"	"8.54"	"4"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf14580"	"6627"	"ENSG00000131876"	"SNRPA1"	"B2R5I6; hsa:6627; P09661; Q8TBD2"	"mRNA Splicing - Major Pathway; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	"mRNA processing"	"3"	"0"	"190.8"	"217.7"	"555.3"	"174.0"	"214.4"	"181.9"	"743.0"	"119.9"	"165.5"	"138.6"	"163.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15446"	"DNA-directed RNA polymerase I subunit RPA34 OS=Homo sapiens OX=9606 GN=CD3EAP PE=1 SV=1"	"6"	"2"	"4"	"2"	"510"	"55.0"	"8.51"	"897.07"	"8.54"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;signal transduction"	"cytosol;mitochondrion;nucleus;other cell component"	""	"Pf08208"	"10849"	"ENSG00000117877"	"POLR1G"	"hsa:10849; O15446; Q32N11; Q7Z5U2; Q9UPF6"	"B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"2q13 copy number variation syndrome"	"6"	"0"	"35.3"	"42.2"	"128.6"	"34.2"	"37.1"	"27.8"	"162.7"	"56.2"	"341.1"	"376.3"	"379.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NCW5"	"NAD(P)H-hydrate epimerase OS=Homo sapiens OX=9606 GN=NAXE PE=1 SV=2"	"16"	"3"	"5"	"3"	"288"	"31.7"	"7.66"	"1246.58"	"8.51"	"3"	"2"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"non-structural extracellular;mitochondrion;other cell component"	"other molecular function"	"Pf03853"	"128240"	"ENSG00000163382"	"NAXE"	"B4DGY3; hsa:128240; Q496C6; Q5T3I2; Q8NCW5"	"Nicotinamide salvaging"	""	"1"	"0"	"198.7"	"225.4"	"842.6"	"212.6"	"174.3"	"125.1"	"1086.3"	"119.7"	"149.5"	"106.3"	"106.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BTC0"	"Death-inducer obliterator 1 OS=Homo sapiens OX=9606 GN=DIDO1 PE=1 SV=5"	"1"	"2"	"4"	"2"	"2240"	"243.7"	"7.88"	"886.94"	"8.51"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;signal transduction"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00628, Pf07500, Pf07744"	"11083"	"ENSG00000101191"	"DIDO1"	"A8MY65; B9EH82; E1P5I1; hsa:11083; O15043; Q3ZTL7; Q3ZTL8; Q4VXS1; Q4VXS2; Q4VXV8; Q4VXV9; Q96D72; Q9BQW0; Q9BTC0; Q9BW03; Q9H4G6; Q9H4G7; Q9NTU8; Q9NUM8; Q9UFB6"	""	""	"0"	"0"	"21.1"	"20.7"	"69.9"	"25.1"	"23.3"	"18.5"	"82.0"	"12.4"	"16.4"	"22.6"	"15.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NCA5"	"Protein FAM98A OS=Homo sapiens OX=9606 GN=FAM98A PE=1 SV=2"	"6"	"3"	"5"	"1"	"518"	"55.2"	"8.95"	"1073.73"	"8.44"	"3"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf10239"	"25940"	"ENSG00000119812"	"FAM98A"	"B2RNA2; hsa:25940; Q8NCA5; Q9Y3Y6"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13084"	"39S ribosomal protein L28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL28 PE=1 SV=4"	"14"	"3"	"5"	"3"	"256"	"30.1"	"8.29"	"1384.30"	"8.43"	"3"	"2"	"protein metabolism;other metabolic processes"	"other membranes;cytosol;mitochondrion;translational apparatus"	"other molecular function"	"Pf00830"	"10573"	"ENSG00000086504"	"MRPL28"	"B2RCM4; D3DU46; hsa:10573; Q13084; Q4TT39; Q96S26; Q9BQD8; Q9BR04"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"137.0"	"164.2"	"614.8"	"172.1"	"119.7"	"107.8"	"748.9"	"61.3"	"101.9"	"77.7"	"96.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19447"	"General transcription and DNA repair factor IIH helicase subunit XPB OS=Homo sapiens OX=9606 GN=ERCC3 PE=1 SV=1"	"7"	"4"	"6"	"4"	"782"	"89.2"	"7.23"	"843.13"	"8.42"	"3"	"3"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04851, Pf13625, Pf16203"	"2071"	"ENSG00000163161"	"ERCC3"	"hsa:2071; P19447; Q53QM0"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Dual Incision in GG-NER"	"Eukaryotic transcription initiation; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; 11p11.2 copy number variation syndrome"	"34"	"0"	"44.1"	"48.7"	"166.3"	"53.4"	"55.2"	"43.9"	"185.9"	"54.5"	"132.9"	"119.3"	"94.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P80723"	"Brain acid soluble protein 1 OS=Homo sapiens OX=9606 GN=BASP1 PE=1 SV=2"	"26"	"3"	"3"	"3"	"227"	"22.7"	"4.63"	"631.90"	"8.40"	"1"	"2"	"RNA metabolism OR transcription;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05466"	"10409"	"ENSG00000176788"	"BASP1"	"B4DJA8; D3DTD5; hsa:10409; O43596; P80723; Q5U0S0; Q9BWA5"	"RHOF GTPase cycle"	""	"1"	"0"	"106.3"	"74.2"	"154.0"	"99.2"	"102.0"	"94.0"	"241.9"	"68.9"	"113.1"	"89.0"	"76.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95989"	"Diphosphoinositol polyphosphate phosphohydrolase 1 OS=Homo sapiens OX=9606 GN=NUDT3 PE=1 SV=1"	"18"	"3"	"4"	"2"	"172"	"19.5"	"6.34"	"348.76"	"8.38"	"1"	"3"	"cell-cell signaling;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00293"	"11165"	"ENSG00000272325"	"NUDT3"	"B2R8N4; hsa:11165; O95989"	"Synthesis of pyrophosphates in the cytosol"	""	"1"	"0"	"54.1"	"41.2"	"118.9"	"56.5"	"65.2"	"64.1"	"319.1"	"195.2"	"752.4"	"664.7"	"790.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NP81"	"Serine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=SARS2 PE=1 SV=1"	"8"	"3"	"5"	"3"	"518"	"58.2"	"8.13"	"1050.99"	"8.36"	"3"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00587"	"54938"	"ENSG00000104835; ENSG00000283104"	"SARS2"	"A6NHW7; B4DE10; hsa:54938; Q9BVP3; Q9NP81"	"Mitochondrial tRNA aminoacylation"	""	"1"	"0"	"29.1"	"36.7"	"111.1"	"35.9"	"29.0"	"21.4"	"144.1"	"29.1"	"43.9"	"30.3"	"33.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75475"	"PC4 and SFRS1-interacting protein OS=Homo sapiens OX=9606 GN=PSIP1 PE=1 SV=1"	"6"	"3"	"5"	"3"	"530"	"60.1"	"9.13"	"746.53"	"8.36"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00855, Pf11467"	"11168"	"ENSG00000164985"	"PSIP1"	"D3DRI9; hsa:11168; O00256; O75475; O95368; Q6P391; Q86YB9; Q9NZI3; Q9UER6"	"Vpr-mediated nuclear import of PICs; Formation of WDR5-containing histone-modifying complexes; 2-LTR circle formation; Integration of viral DNA into host genomic DNA; Autointegration results in viral DNA circles; APOBEC3G mediated resistance to HIV-1 infection"	"MECP2 and associated Rett syndrome"	"8"	"0"	"168.8"	"159.4"	"479.4"	"154.2"	"151.9"	"111.4"	"633.5"	"81.1"	"190.1"	"143.3"	"186.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P28370"	"Probable global transcription activator SNF2L1 OS=Homo sapiens OX=9606 GN=SMARCA1 PE=1 SV=2"	"3"	"3"	"6"	"3"	"1054"	"122.5"	"8.09"	"1011.78"	"8.32"	"3"	"3"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf09110, Pf09111"	"6594"	"ENSG00000102038"	"SMARCA1"	"hsa:6594; P28370; Q5JV41; Q5JV42"	""	"Nuclear receptors meta-pathway; Rett syndrome causing genes"	"2"	"0"	"251.4"	"232.4"	"818.6"	"228.9"	"190.8"	"126.7"	"746.9"	"117.8"	"148.4"	"162.8"	"236.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96A35"	"39S ribosomal protein L24, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL24 PE=1 SV=1"	"18"	"3"	"5"	"3"	"216"	"24.9"	"9.29"	"639.10"	"8.31"	"2"	"3"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00467, Pf17136"	"79590"	"ENSG00000143314"	"MRPL24"	"D3DVC8; hsa:79590; Q53G65; Q53HT0; Q5SYZ9; Q5SZ00; Q5SZ02; Q96A35; Q96Q70; Q9H7G3"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"198.2"	"194.9"	"608.1"	"171.4"	"180.9"	"137.6"	"699.3"	"103.8"	"158.6"	"126.3"	"131.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07741"	"Adenine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=APRT PE=1 SV=2"	"15"	"2"	"4"	"2"	"180"	"19.6"	"6.02"	"933.40"	"8.30"	"2"	"2"	"other metabolic processes;transport;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00156"	"353"	"ENSG00000198931"	"APRT"	"G5E9J2; hsa:353; P07741; Q3KP55; Q68DF9"	"Neutrophil degranulation; Purine salvage; Defective APRT disrupts adenine salvage"	""	"3"	"0"	"101.7"	"116.7"	"556.4"	"98.2"	"86.2"	"70.6"	"708.4"	"71.7"	"87.2"	"71.9"	"59.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14735"	"Insulin-degrading enzyme OS=Homo sapiens OX=9606 GN=IDE PE=1 SV=4"	"3"	"3"	"5"	"3"	"1019"	"117.9"	"6.61"	"546.62"	"8.29"	"2"	"3"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00675, Pf05193, Pf16187"	"3416"	"ENSG00000119912"	"IDE"	"B2R721; B7ZAU2; D3DR35; hsa:3416; P14735; Q5T5N2"	"Peroxisomal protein import; Ub-specific processing proteases; Insulin receptor recycling"	"Alzheimer's disease and miRNA effects; Alzheimer's disease"	"5"	"0"	"131.5"	"145.0"	"466.0"	"140.0"	"136.6"	"104.0"	"590.6"	"96.7"	"124.3"	"119.1"	"106.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60832"	"H/ACA ribonucleoprotein complex subunit DKC1 OS=Homo sapiens OX=9606 GN=DKC1 PE=1 SV=3"	"6"	"2"	"4"	"2"	"514"	"57.6"	"9.42"	"916.75"	"8.28"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01472, Pf01509, Pf08068, Pf16198"	"1736"	"ENSG00000130826"	"DKC1"	"F5BSB3; hsa:1736; O43845; O60832; Q96G67; Q9Y505"	"rRNA modification in the nucleus and cytosol; Telomere Extension By Telomerase"	""	"2"	"0"	"47.4"	"64.5"	"237.1"	"58.7"	"54.7"	"37.3"	"223.0"	"23.4"	"39.1"	"40.5"	"36.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H2U1"	"ATP-dependent DNA/RNA helicase DHX36 OS=Homo sapiens OX=9606 GN=DHX36 PE=1 SV=2"	"5"	"5"	"8"	"4"	"1008"	"114.7"	"7.68"	"1576.83"	"8.26"	"5"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"170506"	"ENSG00000174953"	"DHX36"	"B2RB00; hsa:170506; Q70JU3; Q8IYE5; Q9H2U1; Q9P240"	"DEx/H-box helicases activate type I IFN and inflammatory cytokines production"	"VEGFA-VEGFR2 signaling"	"2"	"1"	"316.8"	"324.8"	"900.3"	"334.4"	"284.1"	"258.3"	"930.4"	"194.9"	"351.5"	"369.1"	"568.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P28482"	"Mitogen-activated protein kinase 1 OS=Homo sapiens OX=9606 GN=MAPK1 PE=1 SV=3"	"7"	"3"	"7"	"3"	"360"	"41.4"	"6.98"	"1119.40"	"8.25"	"3"	"2"	"cell-cell signaling;cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00069"	"5594"	"ENSG00000100030"	"MAPK1"	"A8CZ64; hsa:5594; P28482"	"Neutrophil degranulation; Regulation of actin dynamics for phagocytic cup formation; Recycling pathway of L1; FCERI mediated MAPK activation; FCGR3A-mediated phagocytosis; NPAS4 regulates expression of target genes; RHO GTPases Activate WASPs and WAVEs; Regulation of HSF1-mediated heat shock response; Signaling by BRAF and RAF1 fusions; Thrombin signalling through proteinase activated receptors (PARs); SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Oxidative Stress Induced Senescence; Regulation of PTEN gene transcription; Signaling by NODAL; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Interferon gamma signaling; Oncogene Induced Senescence; Senescence-Associated Secretory Phenotype (SASP); Growth hormone receptor signaling; Regulation of the apoptosome activity; Signal transduction by L1; Estrogen-dependent nuclear events downstream of ESR-membrane signaling; NCAM signaling for neurite out-growth; Downregulation of SMAD2/3:SMAD4 transcriptional activity; RUNX2 regulates osteoblast differentiation; RSK activation; Estrogen-stimulated signaling through PRKCZ; Spry regulation of FGF signaling; Suppression of apoptosis; MAPK1 (ERK2) activation; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; IFNG signaling activates MAPKs; Golgi Cisternae Pericentriolar Stack Reorganization; Signaling by Activin; Activation of the AP-1 family of transcription factors; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; Frs2-mediated activation; Signal attenuation; Gastrin-CREB signalling pathway via PKC and MAPK; Nuclear events stimulated by ALK signaling in cancer; ESR-mediated signaling; Negative feedback regulation of MAPK pathway; Advanced glycosylation endproduct receptor signaling; RHO GTPases Activate NADPH Oxidases; ERKs are inactivated; Signaling by MAP2K mutants; phospho-PLA2 pathway; Signaling by MAPK mutants"	"IL-5 signaling pathway; Osteopontin signaling; Physiological and pathological hypertrophy of the heart; Angiogenesis; MicroRNAs in cardiomyocyte hypertrophy; Type II diabetes mellitus; Heart development; Integrin-mediated cell adhesion; IL-1 signaling pathway; Thyroxine (thyroid hormone) production; RANKL/RANK signaling pathway; Thyroid stimulating hormone (TSH) signaling pathway; Leptin signaling pathway; Follicle stimulating hormone (FSH) signaling pathway; TNF-related weak inducer of apoptosis (TWEAK) signaling pathway; Prolactin signaling pathway; IL-7 signaling pathway; Alzheimer's disease and miRNA effects; IL-17 signaling pathway; Endothelin pathways; IL-9 signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; Glioblastoma signaling pathways; Androgen receptor network in prostate cancer; B cell receptor signaling pathway; TNF-alpha signaling pathway; AGE/RAGE pathway; Interleukin-11 signaling pathway; Corticotropin-releasing hormone signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Spinal cord injury; Alpha 6 beta 4 signaling pathway; PDGF pathway; Aryl hydrocarbon receptor pathway; S1P receptor signal transduction; Ebstein-Barr virus LMP1 signaling; Common pathways underlying drug addiction; Interleukin-1 (IL-1) structural pathway; Cardiac hypertrophic response; Bladder cancer; IL-3 signaling pathway; Apoptosis-related network due to altered Notch3 in ovarian cancer; TCA cycle nutrient use and invasiveness of ovarian cancer; Kit receptor signaling pathway; Focal adhesion; Hepatocyte growth factor receptor signaling; MFAP5-mediated ovarian cancer cell motility and invasiveness; RAC1/PAK1/p38/MMP2 pathway; Wnt signaling pathway; IL6 signaling pathway; Hypothesized pathways in pathogenesis of cardiovascular disease; BDNF-TrkB signaling; Physico-chemical features and toxicity-associated pathways; MAPK signaling pathway; MAPK and NFkB signaling pathways inhibited by Yersinia YopJ; ERK pathway in Huntington's disease; Toll-like receptor signaling related to MyD88; TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition; 4-hydroxytamoxifen, dexamethasone, and retinoic acids regulation of p27 expression; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Chemokine signaling pathway; Embryonic stem cell pluripotency pathways; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; IL-4 signaling pathway; Prion disease pathway; Endometrial cancer; PI3K-Akt signaling pathway; Chromosomal and microsatellite instability in colorectal cancer ; Ebola virus infection in host; MAPK cascade; Ras signaling; Epithelial to mesenchymal transition in colorectal cancer; Non-small cell lung cancer; Breast cancer pathway; Pancreatic adenocarcinoma pathway; Acute viral myocarditis; Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells; Neovascularisation processes; Non-genomic actions of 1,25 dihydroxyvitamin D3; EGF/EGFR signaling pathway; Bile acids synthesis and enterohepatic circulation ; Resistin as a regulator of inflammation; Relationship between inflammation, COX-2 and EGFR; Envelope proteins and their potential roles in EDMD physiopathology; Regulatory circuits of the STAT3 signaling pathway; Synaptic signaling pathways associated with autism spectrum disorder; Fragile X syndrome; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Translation inhibitors in chronically activated PDGFRA cells; Gastrin signaling pathway; Hepatitis B infection; Melanoma; Netrin-UNC5B signaling pathway; IL-18 signaling pathway; FGFR3 signaling in chondrocyte proliferation and terminal differentiation; Osteoblast differentiation and related diseases; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; Regucalcin in proximal tubule epithelial kidney cells; Kisspeptin/kisspeptin receptor system in the ovary; MAP3K1 role in promoting and blocking gonadal determination; CAMKK2 pathway; Disruption of postsynaptic signaling by CNV; Host-pathogen interaction of human coronaviruses - MAPK signaling; IL-2 signaling pathway; RAS and bradykinin pathways in COVID-19; Angiotensin II receptor type 1 pathway; Kallmann syndrome; Neuroinflammation and glutamatergic signaling; Pleural mesothelioma; Orexin receptor pathway; CCL18 signaling pathway; Regulation of actin cytoskeleton; Sphingolipid metabolism in senescence; Alzheimer's disease; Th17 cell differentiation pathway; GDNF signaling; 2q11.2 copy number variation syndrome; 2q13 copy number variation syndrome; Hippocampal synaptogenesis and neurogenesis; Comprehensive IL-17A signaling; Genetic causes of porto-sinusoidal vascular disease; Female steroid hormones in cardiomyocyte energy metabolism; Cardiomyocyte signaling pathways converging on Titin; IL-26 signaling pathways; A network map of Macrophage-stimulating protein (MSP) signaling; Role of hypoxia, angiogenesis, and FGF pathway in OA chondrocyte hypertrophy; EPO receptor signaling; ErbB signaling pathway; T-cell receptor signaling pathway; DNA damage response (only ATM dependent); Estrogen signaling pathway; Vitamin A and carotenoid metabolism; Toll-like receptor signaling pathway"	"197"	"0"	"237.7"	"296.7"	"1014.5"	"288.0"	"274.0"	"236.9"	"1175.6"	"227.3"	"318.7"	"257.6"	"326.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P00491"	"Purine nucleoside phosphorylase OS=Homo sapiens OX=9606 GN=PNP PE=1 SV=2"	"15"	"3"	"5"	"3"	"289"	"32.1"	"6.95"	"1113.88"	"8.25"	"3"	"2"	"other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf01048"	"4860"	"ENSG00000198805"	"PNP"	"B2R8S5; D3DS00; hsa:4860; P00491; Q15160; Q5PZ03"	"Neutrophil degranulation; Purine catabolism; Ribavirin ADME; Purine salvage; Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine"	"VEGFA-VEGFR2 signaling"	"6"	"0"	"284.4"	"324.2"	"1196.7"	"261.9"	"235.8"	"145.9"	"1526.4"	"170.2"	"214.4"	"144.5"	"138.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y224"	"RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1"	"11"	"2"	"4"	"2"	"244"	"28.1"	"6.65"	"1058.81"	"8.24"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf10036"	"51637"	"ENSG00000087302"	"RTRAF"	"hsa:51637; Q9Y224"	"tRNA processing in the nucleus"	""	"1"	"0"	"50.7"	"64.1"	"264.7"	"75.4"	"47.8"	"46.2"	"242.9"	"15.8"	"27.4"	"18.2"	"14.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BPW8"	"Protein NipSnap homolog 1 OS=Homo sapiens OX=9606 GN=NIPSNAP1 PE=1 SV=1"	"10"	"3"	"4"	"2"	"284"	"33.3"	"9.31"	"924.20"	"8.23"	"2"	"2"	"other biological processes"	"plasma membrane;other membranes;mitochondrion"	"other molecular function"	"Pf07978"	"8508"	"ENSG00000184117"	"NIPSNAP1"	"B2RAY3; hsa:8508; O43800; Q9BPW8"	""	""	"0"	"1"	"155.3"	"186.3"	"502.2"	"159.3"	"123.1"	"107.9"	"533.5"	"85.3"	"107.1"	"87.0"	"103.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NQ50"	"39S ribosomal protein L40, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL40 PE=1 SV=1"	"12"	"2"	"4"	"2"	"206"	"24.5"	"9.63"	"995.30"	"8.22"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	""	"Pf09812"	"64976"	"ENSG00000185608"	"MRPL40"	"B3KVZ7; hsa:64976; O95134; Q9NQ50"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"22q11.2 copy number variation syndrome"	"4"	"0"	"11.2"	"13.5"	"32.3"	"9.4"	"7.4"	"9.8"	"34.7"	"5.6"	"8.8"	"4.9"	"6.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NVZ3"	"Adaptin ear-binding coat-associated protein 2 OS=Homo sapiens OX=9606 GN=NECAP2 PE=1 SV=1"	"11"	"2"	"4"	"2"	"263"	"28.3"	"8.38"	"784.04"	"8.21"	"2"	"2"	"transport"	"plasma membrane;other membranes"	""	"Pf07933"	"55707"	"ENSG00000157191"	"NECAP2"	"B4DY19; E9PGQ8; hsa:55707; Q5VSU4; Q5VSU5; Q9H7L1; Q9H8L1; Q9NVZ3"	"Cargo recognition for clathrin-mediated endocytosis"	""	"2"	"0"	"31.9"	"27.5"	"92.2"	"25.9"	"32.2"	"18.7"	"116.9"	"50.2"	"151.3"	"162.3"	"190.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WWK9"	"Cytoskeleton-associated protein 2 OS=Homo sapiens OX=9606 GN=CKAP2 PE=1 SV=1"	"5"	"4"	"6"	"4"	"683"	"76.9"	"9.41"	"1514.84"	"8.20"	"4"	"2"	"cell cycle OR cell proliferation;other biological processes"	"cytoskeleton;other cell component"	""	"Pf15297"	"26586"	"ENSG00000136108"	"CKAP2"	"A2BDE0; A5YM58; B4DR35; E9PD90; hsa:26586; Q3KRA5; Q5VXB4; Q8IWV5; Q8IWV6; Q8WWK9; Q96FH9; Q9H012; Q9H0D0; Q9H988; Q9HC49; Q9NVG4"	""	""	"0"	"0"	"159.8"	"149.7"	"381.0"	"143.1"	"155.3"	"122.2"	"880.9"	"302.7"	"528.0"	"471.7"	"507.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQA1"	"Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1"	"6"	"2"	"6"	"2"	"342"	"36.7"	"5.17"	"873.46"	"8.18"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400"	"79084"	"ENSG00000116455"	"WDR77"	"B3KMW6; B4DP38; hsa:79084; Q3LID2; Q53FU2; Q6JZZ5; Q96GK4; Q9BQA1; Q9BWY3"	"snRNP Assembly; RMTs methylate histone arginines"	""	"2"	"0"	"34.4"	"48.4"	"205.4"	"42.7"	"29.6"	"35.7"	"311.4"	"31.9"	"36.7"	"32.5"	"38.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BRA2"	"Thioredoxin domain-containing protein 17 OS=Homo sapiens OX=9606 GN=TXNDC17 PE=1 SV=1"	"31"	"3"	"6"	"3"	"123"	"13.9"	"5.52"	"952.38"	"8.17"	"3"	"3"	"signal transduction;other biological processes"	"cytosol"	"other molecular function"	"Pf06110"	"84817"	"ENSG00000129235"	"TXNDC17"	"A8K7E8; hsa:84817; Q9BRA2"	""	""	"0"	"0"	"125.0"	"177.7"	"916.5"	"163.2"	"115.7"	"78.4"	"1269.9"	"102.6"	"117.3"	"85.1"	"72.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00139"	"Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3"	"3"	"2"	"4"	"2"	"706"	"79.9"	"6.68"	"735.24"	"8.11"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225"	"3796"	"ENSG00000068796"	"KIF2A"	"A5YM42; A5YM54; B4DY54; D3DW97; E9PB70; hsa:3796; O00139; Q7Z5I3; Q8N5Q7"	"COPI-dependent Golgi-to-ER retrograde traffic; Separation of Sister Chromatids; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Kinesins; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	""	"9"	"0"	"112.4"	"113.5"	"411.8"	"104.8"	"99.4"	"75.2"	"353.0"	"38.0"	"59.3"	"48.9"	"42.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P36507"	"Dual specificity mitogen-activated protein kinase kinase 2 OS=Homo sapiens OX=9606 GN=MAP2K2 PE=1 SV=1"	"6"	"2"	"4"	"2"	"400"	"44.4"	"6.55"	"965.22"	"8.11"	"2"	"2"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069"	"5605"	"ENSG00000126934"	"MAP2K2"	"hsa:5605; P36507"	"Signaling by BRAF and RAF1 fusions; Uptake and function of anthrax toxins; Signal transduction by L1; RAF activation; MAPK1 (ERK2) activation; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; Frs2-mediated activation; Negative feedback regulation of MAPK pathway; Signaling by MAP2K mutants"	"IL-5 signaling pathway; MicroRNAs in cardiomyocyte hypertrophy; Integrin-mediated cell adhesion; IL-1 signaling pathway; Thyroxine (thyroid hormone) production; Leptin signaling pathway; Prolactin signaling pathway; IL-7 signaling pathway; Alzheimer's disease and miRNA effects; IL-9 signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; Glioblastoma signaling pathways; Androgen receptor network in prostate cancer; B cell receptor signaling pathway; Interleukin-11 signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Amyotrophic lateral sclerosis (ALS); Common pathways underlying drug addiction; Interleukin-1 (IL-1) structural pathway; Cardiac hypertrophic response; Bladder cancer; Kit receptor signaling pathway; Hepatocyte growth factor receptor signaling; IL6 signaling pathway; Pathways affected in adenoid cystic carcinoma; MAPK signaling pathway; T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection; 4-hydroxytamoxifen, dexamethasone, and retinoic acids regulation of p27 expression; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Embryonic stem cell pluripotency pathways; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Endometrial cancer; PI3K-Akt signaling pathway; MAPK cascade; Ras signaling; Epithelial to mesenchymal transition in colorectal cancer; Non-small cell lung cancer; Breast cancer pathway; Pancreatic adenocarcinoma pathway; Ethanol metabolism production of ROS by CYP2E1; EGF/EGFR signaling pathway; Envelope proteins and their potential roles in EDMD physiopathology; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Hepatitis B infection; Melanoma; Netrin-UNC5B signaling pathway; FGFR3 signaling in chondrocyte proliferation and terminal differentiation; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; Kisspeptin/kisspeptin receptor system in the ovary; Host-pathogen interaction of human coronaviruses - MAPK signaling; IL-2 signaling pathway; MAPK pathway in congenital thyroid cancer; Kallmann syndrome; Pleural mesothelioma; Regulation of actin cytoskeleton; Alzheimer's disease; GDNF signaling; A network map of Macrophage-stimulating protein (MSP) signaling; EPO receptor signaling; ErbB signaling pathway; T-cell receptor signaling pathway; Serotonin HTR1 group and FOS pathway; Serotonin receptor 2 and ELK-SRF/GATA4 signaling; Serotonin receptor 4/6/7 and NR3C signaling; Toll-like receptor signaling pathway"	"83"	"0"	"47.5"	"52.6"	"251.9"	"54.1"	"51.6"	"35.9"	"301.2"	"40.6"	"50.4"	"55.0"	"50.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3D9"	"28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2"	"11"	"2"	"6"	"2"	"190"	"21.8"	"8.90"	"1014.46"	"8.11"	"2"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf10484"	"51649"	"ENSG00000181610"	"MRPS23"	"B2R6V3; hsa:51649; Q96Q24; Q9BWH8; Q9P053; Q9Y3D9"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"326.0"	"330.8"	"883.5"	"291.3"	"250.3"	"218.3"	"1030.6"	"162.1"	"190.5"	"149.9"	"176.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61758"	"Prefoldin subunit 3 OS=Homo sapiens OX=9606 GN=VBP1 PE=1 SV=4"	"19"	"3"	"5"	"3"	"197"	"22.6"	"7.11"	"1193.80"	"8.11"	"3"	"2"	"cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02996"	"7411"	"ENSG00000155959"	"VBP1"	"B2R8L5; B4DWR3; F5H2A7; hsa:7411; O55228; P61758; Q15765; Q5JT81; Q86X96"	"Prefoldin mediated transfer of substrate  to CCT/TriC"	"Cellular proteostasis"	"2"	"0"	"137.8"	"154.6"	"673.7"	"165.5"	"152.3"	"110.7"	"865.2"	"79.0"	"99.5"	"89.0"	"84.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60604"	"Ubiquitin-conjugating enzyme E2 G2 OS=Homo sapiens OX=9606 GN=UBE2G2 PE=1 SV=1"	"15"	"1"	"2"	"1"	"165"	"18.6"	"4.70"	""	"8.10"	""	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"ER/Golgi;other cell component"	"other molecular function"	"Pf00179"	"7327"	"ENSG00000184787"	"UBE2G2"	"A6NMQ7; A8K3L4; D3DSL7; hsa:7327; P56554; P60604"	"Antigen processing: Ubiquitination & Proteasome degradation; Synthesis of active ubiquitin: roles of E1 and E2 enzymes"	"Parkin-ubiquitin proteasomal system pathway; Parkinson's disease pathway"	"4"	"0"	"8.2"	"9.2"	"48.6"	"12.0"	"17.3"	"13.1"	"53.4"	"8.9"	"10.2"	"9.3"	"10.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09543"	"2',3'-cyclic-nucleotide 3'-phosphodiesterase OS=Homo sapiens OX=9606 GN=CNP PE=1 SV=2"	"11"	"4"	"7"	"4"	"421"	"47.5"	"9.07"	"1161.44"	"8.06"	"4"	"3"	"cell-cell signaling;cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytoskeleton;mitochondrion;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05881, Pf13671"	"1267"	"ENSG00000173786"	"CNP"	"hsa:1267; P09543"	""	"Glial cell differentiation; MECP2 and associated Rett syndrome; VEGFA-VEGFR2 signaling; FGFR3 signaling in chondrocyte proliferation and terminal differentiation"	"4"	"0"	"200.6"	"190.5"	"740.6"	"167.5"	"139.8"	"122.1"	"610.9"	"91.8"	"113.9"	"102.8"	"102.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16698"	"2,4-dienoyl-CoA reductase, mitochondrial OS=Homo sapiens OX=9606 GN=DECR1 PE=1 SV=1"	"10"	"2"	"3"	"2"	"335"	"36.0"	"9.28"	"254.12"	"8.04"	"1"	"2"	"other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf13561"	"1666"	"ENSG00000104325"	"DECR1"	"B7Z6B8; hsa:1666; Q16698; Q2M304; Q93085"	"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids"	"Fatty acid beta-oxidation; Fatty acid biosynthesis; VEGFA-VEGFR2 signaling"	"4"	"0"	"54.0"	"55.8"	"160.3"	"59.0"	"61.6"	"50.3"	"176.8"	"48.4"	"68.7"	"53.0"	"53.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13247"	"Serine/arginine-rich splicing factor 6 OS=Homo sapiens OX=9606 GN=SRSF6 PE=1 SV=2"	"7"	"3"	"7"	"1"	"344"	"39.6"	"11.43"	"1192.47"	"8.02"	"3"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076"	"6431"	"ENSG00000124193"	"SRSF6"	"B7Z6J3; E1P5W6; hsa:6431; Q13244; Q13245; Q13247; Q96J06; Q9UJB8; Q9Y3N7"	"RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing"	"mRNA processing"	"7"	"0"	"255.8"	"260.7"	"919.8"	"196.9"	"235.3"	"158.0"	"1154.3"	"134.3"	"197.4"	"142.5"	"107.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P20340"	"Ras-related protein Rab-6A OS=Homo sapiens OX=9606 GN=RAB6A PE=1 SV=3"	"16"	"3"	"6"	"2"	"208"	"23.6"	"5.54"	"957.35"	"8.02"	"2"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00071"	"5870"	"ENSG00000175582"	"RAB6A"	"A8K133; B7Z772; F5H668; hsa:5870; P20340; Q1W5D8; Q5U0A8; Q9UBE4"	"Neutrophil degranulation; RAB GEFs exchange GTP for GDP on RABs; RAB geranylgeranylation; COPI-independent Golgi-to-ER retrograde traffic; Pre-NOTCH Processing in Golgi; Retrograde transport at the Trans-Golgi-Network; TBC/RABGAPs"	""	"7"	"0"	"14.3"	"16.1"	"82.5"	"11.8"	"15.6"	"7.2"	"100.3"	"7.5"	"10.1"	"5.7"	"11.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BWF3"	"RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1"	"11"	"3"	"5"	"3"	"364"	"40.3"	"7.08"	"1128.42"	"8.00"	"3"	"2"	"cell-cell signaling;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00098"	"5936"	"ENSG00000173933"	"RBM4"	"B3KUN0; B4E1U0; E7EQS3; hsa:5936; O02916; Q4VC48; Q6P1P2; Q8WU85; Q9BWF3"	"Circadian Clock"	""	"1"	"0"	"142.7"	"148.8"	"458.3"	"126.0"	"132.8"	"106.3"	"526.1"	"83.7"	"103.9"	"103.6"	"102.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15021"	"Condensin complex subunit 1 OS=Homo sapiens OX=9606 GN=NCAPD2 PE=1 SV=3"	"3"	"4"	"6"	"4"	"1401"	"157.1"	"6.61"	"978.41"	"7.99"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf12717, Pf12922"	"9918"	"ENSG00000010292"	"NCAPD2"	"D3DUR4; hsa:9918; Q15021; Q8N6U3"	"Condensation of Prometaphase Chromosomes"	""	"1"	"0"	"181.1"	"211.7"	"829.6"	"179.1"	"165.7"	"128.2"	"760.3"	"78.2"	"117.3"	"115.3"	"91.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UI10"	"Translation initiation factor eIF-2B subunit delta OS=Homo sapiens OX=9606 GN=EIF2B4 PE=1 SV=2"	"5"	"2"	"4"	"2"	"523"	"57.5"	"9.38"	"971.96"	"7.99"	"2"	"2"	"protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01008"	"8890"	"ENSG00000115211"	"EIF2B4"	"hsa:8890; Q53RY7; Q5BJF4; Q9BUV9; Q9UBG4; Q9UI10; Q9UIQ9; Q9UJ95"	"Recycling of eIF2:GDP"	"Translation factors; Primary ovarian insufficiency"	"3"	"0"	"49.5"	"61.0"	"188.5"	"45.7"	"45.8"	"34.1"	"178.4"	"26.4"	"32.7"	"29.2"	"31.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14974"	"Protein phosphatase 1 regulatory subunit 12A OS=Homo sapiens OX=9606 GN=PPP1R12A PE=1 SV=1"	"4"	"3"	"6"	"3"	"1030"	"115.2"	"5.40"	"926.74"	"7.99"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00023, Pf15898"	"4659"	"ENSG00000058272"	"PPP1R12A"	"B4DZ09; F8VWB4; hsa:4659; O14974; Q2NKL4; Q569H0; Q86WU3; Q8NFR6; Q9BYH0"	"Regulation of PLK1 Activity at G2/M Transition; RHO GTPases activate CIT; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; RHO GTPases activate PAKs"	"Focal adhesion; Hippo-Merlin signaling dysregulation; Regulation of actin cytoskeleton"	"8"	"0"	"44.5"	"49.7"	"135.7"	"36.1"	"36.4"	"39.6"	"157.1"	"21.3"	"36.2"	"30.7"	"31.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z406"	"Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2"	"2"	"4"	"7"	"1"	"1995"	"227.7"	"5.60"	"1603.78"	"7.99"	"4"	"3"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00063, Pf01576, Pf02736"	"79784"	"ENSG00000105357"	"MYH14"	"B0I1S2; C3TTN4; hsa:79784; Q5CZ75; Q6XYE4; Q76B62; Q7Z406; Q8WV23; Q96I22; Q9BT27; Q9BW35; Q9H882"	"RHO GTPases activate CIT; EPHA-mediated growth cone collapse; Sema4D induced cell migration and growth-cone collapse; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; RHO GTPases activate PAKs"	""	"6"	"0"	"40.6"	"31.1"	"89.5"	"42.9"	"27.4"	"18.6"	"117.4"	"17.2"	"28.8"	"19.5"	"26.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2W2"	"WW domain-binding protein 11 OS=Homo sapiens OX=9606 GN=WBP11 PE=1 SV=1"	"5"	"2"	"3"	"2"	"641"	"70.0"	"8.38"	"514.63"	"7.99"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09429"	"51729"	"ENSG00000084463"	"WBP11"	"hsa:51729; Q96AY8; Q9Y2W2"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"22.6"	"17.9"	"58.7"	"16.1"	"24.4"	"18.3"	"76.1"	"14.5"	"20.5"	"17.7"	"13.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P32322"	"Pyrroline-5-carboxylate reductase 1, mitochondrial OS=Homo sapiens OX=9606 GN=PYCR1 PE=1 SV=2"	"11"	"3"	"6"	"2"	"319"	"33.3"	"7.61"	"1112.02"	"7.98"	"3"	"3"	"other metabolic processes;stress response;other biological processes"	"mitochondrion"	"other molecular function"	"Pf03807, Pf14748"	"5831"	"ENSG00000183010"	"PYCR1"	"A6NFM2; B4DMU0; hsa:5831; P32322; Q6FHI4; Q96DI6; Q9HBQ4"	"Glutamate and glutamine metabolism"	"Amino acid metabolism; Metabolic reprogramming in colon cancer"	"3"	"0"	"123.9"	"166.2"	"349.3"	"165.4"	"172.2"	"166.2"	"340.7"	"101.0"	"163.8"	"98.3"	"123.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P33316"	"Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=DUT PE=1 SV=4"	"13"	"3"	"7"	"3"	"252"	"26.5"	"9.36"	"1274.50"	"7.98"	"3"	"2"	"DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;mitochondrion;nucleus"	"signal transduction activity or receptor binding;other molecular function"	"Pf00692"	"1854"	"ENSG00000128951"	"DUT"	"A8K650; B4DPR5; hsa:1854; O14785; P33316; Q16708; Q16860; Q6FHN1; Q6NSA3; Q96Q81"	""	"Pyrimidine metabolism"	"1"	"0"	"196.8"	"224.1"	"742.2"	"222.0"	"214.7"	"170.5"	"869.5"	"154.7"	"197.2"	"162.6"	"164.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49419"	"Alpha-aminoadipic semialdehyde dehydrogenase OS=Homo sapiens OX=9606 GN=ALDH7A1 PE=1 SV=5"	"5"	"2"	"4"	"2"	"539"	"58.5"	"7.99"	"816.63"	"7.97"	"2"	"2"	"other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf00171"	"501"	"ENSG00000164904"	"ALDH7A1"	"B2R669; B4DIC7; B4DMA0; E7EPT3; hsa:501; O14619; P49419; Q6IPU8; Q9BUL4"	"Lysine catabolism; Choline catabolism"	"Amino acid metabolism; Vitamin B6-dependent and responsive disorders; Cerebral organic acidurias, including diseases; Diet-dependent trimethylamine/trimethylamine N-oxide metabolism"	"6"	"0"	"39.5"	"44.9"	"154.2"	"35.9"	"42.8"	"35.8"	"229.0"	"23.9"	"36.6"	"35.0"	"29.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43768"	"Alpha-endosulfine OS=Homo sapiens OX=9606 GN=ENSA PE=1 SV=1"	"37"	"4"	"7"	"4"	"121"	"13.4"	"7.24"	"1161.54"	"7.97"	"4"	"3"	"cell cycle OR cell proliferation;other biological processes"	"nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf04667"	"2029"	"ENSG00000143420"	"ENSA"	"A8K1Z9; E9PB69; hsa:2029; O43768; Q5T5H2; Q68D48; Q6FHW0; Q6IAM4; Q6NUL2; Q6VUC6; Q6VUC7; Q6VUC8; Q6VUC9; Q6VUD0; Q6VUD1; Q9NRZ0"	"MASTL Facilitates Mitotic Progression"	""	"1"	"0"	"312.6"	"364.7"	"1327.0"	"352.7"	"337.2"	"219.8"	"2188.1"	"286.6"	"437.7"	"380.2"	"455.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P24539"	"ATP synthase F(0) complex subunit B1, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PB PE=1 SV=2"	"13"	"3"	"6"	"3"	"256"	"28.9"	"9.36"	"1029.49"	"7.97"	"3"	"3"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf05405"	"515"	"ENSG00000116459"	"ATP5PB"	"hsa:515; P24539; Q9BQ68; Q9BRU8"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"Electron transport chain: OXPHOS system in mitochondria; 7q11.23 copy number variation syndrome; Oxidative phosphorylation"	"5"	"0"	"169.5"	"156.5"	"596.3"	"157.3"	"136.6"	"121.2"	"502.9"	"58.2"	"112.5"	"94.0"	"98.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19784"	"Casein kinase II subunit alpha' OS=Homo sapiens OX=9606 GN=CSNK2A2 PE=1 SV=1"	"9"	"3"	"7"	"3"	"350"	"41.2"	"8.56"	"839.90"	"7.95"	"3"	"3"	"cell-cell signaling;cell cycle OR cell proliferation;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"1459"	"ENSG00000070770"	"CSNK2A2"	"hsa:1459; P19784"	"Regulation of PTEN stability and activity; KEAP1-NFE2L2 pathway; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Regulation of TP53 Activity through Phosphorylation; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; WNT mediated activation of DVL; Signal transduction by L1; Receptor Mediated Mitophagy; Condensation of Prometaphase Chromosomes; Synthesis of PC"	"Alzheimer's disease and miRNA effects; Allograft rejection; lncRNA in canonical Wnt signaling and colorectal cancer; Breast cancer pathway; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Measles virus infection; Pleural mesothelioma; Alzheimer's disease"	"19"	"0"	"165.1"	"207.6"	"683.4"	"157.1"	"131.1"	"119.9"	"934.1"	"248.5"	"276.3"	"314.6"	"668.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UN37"	"Vacuolar protein sorting-associated protein 4A OS=Homo sapiens OX=9606 GN=VPS4A PE=1 SV=1"	"11"	"4"	"7"	"2"	"437"	"48.9"	"7.80"	"1594.90"	"7.92"	"4"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00004, Pf04212, Pf09336, Pf17862"	"27183"	"ENSG00000132612"	"VPS4A"	"B2RCB7; hsa:27183; Q8TF07; Q9UI03; Q9UN37; Q9Y582"	"Budding and maturation of HIV virion; Endosomal Sorting Complex Required For Transport (ESCRT); HCMV Late Events; Sealing of the nuclear envelope (NE) by ESCRT-III"	"Ebola virus infection in host; Ciliary landscape"	"6"	"0"	"28.7"	"28.0"	"134.1"	"20.7"	"21.7"	"17.8"	"203.9"	"17.4"	"12.8"	"14.0"	"13.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y314"	"Nitric oxide synthase-interacting protein OS=Homo sapiens OX=9606 GN=NOSIP PE=1 SV=1"	"12"	"2"	"3"	"2"	"301"	"33.2"	"8.82"	"376.46"	"7.89"	"1"	"2"	"other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf15906"	"51070"	"ENSG00000142546"	"NOSIP"	"hsa:51070; Q96FD2; Q9Y314"	"NOSIP mediated eNOS trafficking"	""	"1"	"0"	"58.8"	"75.4"	"208.6"	"54.7"	"55.9"	"44.6"	"279.7"	"71.2"	"107.9"	"190.0"	"326.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q969H8"	"Myeloid-derived growth factor OS=Homo sapiens OX=9606 GN=MYDGF PE=1 SV=1"	"24"	"4"	"7"	"4"	"173"	"18.8"	"6.68"	"1358.47"	"7.88"	"4"	"3"	"developmental processes;other biological processes"	"non-structural extracellular;ER/Golgi"	""	"Pf10572"	"56005"	"ENSG00000074842"	"MYDGF"	"D6W628; hsa:56005; O75256; O75272; Q969H8; Q9BTK7; Q9NP69"	"XBP1(S) activates chaperone genes"	""	"1"	"0"	"298.9"	"345.7"	"1562.9"	"365.2"	"267.0"	"177.5"	"2092.6"	"224.4"	"267.5"	"183.0"	"176.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92522"	"Histone H1.10 OS=Homo sapiens OX=9606 GN=H1-10 PE=1 SV=1"	"13"	"2"	"4"	"2"	"213"	"22.5"	"10.76"	"810.34"	"7.87"	"2"	"2"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00538"	"8971"	"ENSG00000184897"	"H1-10"	"hsa:8971; Q92522"	""	""	"0"	"0"	"126.2"	"114.5"	"356.7"	"121.7"	"122.2"	"90.5"	"359.3"	"48.0"	"67.0"	"53.2"	"79.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14649"	"Myosin light chain 6B OS=Homo sapiens OX=9606 GN=MYL6B PE=1 SV=1"	"14"	"2"	"4"	"1"	"208"	"22.8"	"5.73"	"858.68"	"7.86"	"2"	"2"	"other biological processes"	"cytosol;cytoskeleton"	"cytoskeletal activity;other molecular function"	""	"140465"	"ENSG00000196465"	"MYL6B"	"hsa:140465; P14649"	"Smooth Muscle Contraction"	"Ciliary landscape"	"2"	"0"	"13.3"	"12.1"	"53.0"	"11.5"	"12.6"	"8.5"	"40.6"	"7.4"	"11.8"	"7.1"	"11.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13526"	"Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 OS=Homo sapiens OX=9606 GN=PIN1 PE=1 SV=1"	"22"	"2"	"3"	"2"	"163"	"18.2"	"8.82"	"461.83"	"7.85"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00397, Pf00639"	"5300"	"ENSG00000127445"	"PIN1"	"A8K4V9; hsa:5300; Q13526; Q53X75"	"Regulation of TP53 Activity through Phosphorylation; ISG15 antiviral mechanism; Negative regulators of DDX58/IFIH1 signaling; PI5P Regulates TP53 Acetylation; RHO GTPases Activate NADPH Oxidases"	"Novel intracellular components of RIG-I-like receptor pathway"	"6"	"0"	"12.4"	"11.2"	"35.8"	"12.2"	"9.5"	"8.1"	"54.0"	"6.2"	"12.4"	"9.1"	"7.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H3U1"	"Protein unc-45 homolog A OS=Homo sapiens OX=9606 GN=UNC45A PE=1 SV=1"	"3"	"2"	"4"	"2"	"944"	"103.0"	"6.07"	"876.11"	"7.85"	"2"	"2"	"other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf11701, Pf13181, Pf13432"	"55898"	"ENSG00000140553"	"UNC45A"	"A8K6F7; hsa:55898; Q7L3Y6; Q9H3U1; Q9H3U8; Q9NSE8; Q9NSE9"	""	""	"0"	"0"	"18.2"	"22.8"	"79.4"	"17.7"	"16.4"	"11.2"	"93.1"	"6.5"	"12.5"	"7.5"	"10.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52815"	"39S ribosomal protein L12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL12 PE=1 SV=2"	"12"	"3"	"6"	"3"	"198"	"21.3"	"8.87"	"1040.16"	"7.84"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00542, Pf16320"	"6182"	"ENSG00000262814"	"MRPL12"	"hsa:6182; P52815; Q969U0; Q9HCA2; Q9UQJ3"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"44.2"	"40.8"	"170.8"	"43.3"	"37.1"	"35.6"	"191.2"	"20.8"	"32.6"	"29.3"	"26.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19404"	"NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV2 PE=1 SV=2"	"10"	"2"	"4"	"2"	"249"	"27.4"	"8.06"	"687.85"	"7.84"	"2"	"2"	"other metabolic processes;transport;developmental processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf01257"	"4729"	"ENSG00000178127"	"NDUFV2"	"hsa:4729; P19404; Q9BV41"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"5"	"0"	"191.3"	"210.7"	"722.2"	"211.1"	"209.3"	"180.5"	"677.5"	"123.1"	"172.7"	"156.5"	"140.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N684"	"Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1"	"7"	"2"	"4"	"2"	"471"	"52.0"	"8.00"	"914.72"	"7.84"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"79869"	"ENSG00000149532"	"CPSF7"	"B3KU04; C9K0Q4; hsa:79869; Q7Z3H9; Q8N684; Q9H025; Q9H9V1"	"RHOBTB1 GTPase cycle; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	""	"5"	"0"	"60.0"	"59.4"	"146.1"	"50.2"	"41.8"	"39.3"	"167.8"	"28.7"	"52.6"	"39.0"	"45.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55769"	"NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3"	"22"	"2"	"3"	"2"	"128"	"14.2"	"8.46"	"290.44"	"7.83"	"1"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01248"	"4809"	"ENSG00000100138"	"SNU13"	"hsa:4809; P55769"	"mRNA Splicing - Major Pathway; Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"mRNA processing"	"4"	"0"	"73.8"	"81.0"	"244.3"	"89.3"	"94.1"	"71.4"	"288.0"	"75.8"	"148.2"	"193.8"	"345.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15717"	"ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2"	"10"	"3"	"6"	"3"	"326"	"36.1"	"9.17"	"1060.10"	"7.83"	"3"	"3"	"cell organization and biogenesis;transport;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"1994"	"ENSG00000066044"	"ELAVL1"	"B4DVB8; hsa:1994; Q15717; Q53XN6; Q9BTT1"	"HuR (ELAVL1) binds and stabilizes mRNA"	"AMP-activated protein kinase signaling; Endoderm differentiation; Pre-implantation embryo; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Gastrin signaling pathway; IL-18 signaling pathway; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; 1p36 copy number variation syndrome"	"10"	"0"	"225.4"	"239.1"	"757.8"	"184.5"	"185.2"	"155.5"	"808.5"	"96.0"	"138.2"	"124.9"	"145.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6Y7W6"	"GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1"	"3"	"2"	"3"	"2"	"1299"	"150.0"	"5.54"	"633.21"	"7.82"	"1"	"2"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf02213"	"26058"	"ENSG00000204120"	"GIGYF2"	"A6H8W4; B9EG55; E9PBB0; hsa:26058; O75137; Q6Y7W6; Q7Z2Z8; Q7Z3I2; Q96HU4; Q9NV82"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"57.4"	"60.0"	"140.0"	"45.6"	"55.6"	"36.9"	"153.0"	"28.4"	"37.6"	"34.1"	"30.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7L2H7"	"Eukaryotic translation initiation factor 3 subunit M OS=Homo sapiens OX=9606 GN=EIF3M PE=1 SV=1"	"8"	"2"	"4"	"2"	"374"	"42.5"	"5.63"	"933.60"	"7.82"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01399, Pf18005"	"10480"	"ENSG00000149100"	"EIF3M"	"A8K7X4; B4E2Q4; hsa:10480; O60735; Q2F836; Q53HL6; Q7L2H7; Q9BXW1"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	""	"6"	"0"	"139.5"	"116.4"	"437.0"	"100.7"	"73.5"	"56.7"	"249.3"	"25.3"	"29.9"	"26.3"	"29.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92973"	"Transportin-1 OS=Homo sapiens OX=9606 GN=TNPO1 PE=1 SV=2"	"5"	"5"	"7"	"1"	"898"	"102.3"	"4.98"	"1219.97"	"7.80"	"4"	"3"	"transport"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf03810, Pf13513"	"3842"	"ENSG00000083312"	"TNPO1"	"B4DVC6; hsa:3842; Q92957; Q92973; Q92975"	"Intraflagellar transport; Postmitotic nuclear pore complex (NPC) reformation; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"	"22q11.2 copy number variation syndrome"	"4"	"4"	"494.0"	"506.6"	"2460.0"	"455.7"	"329.2"	"244.6"	"2298.5"	"145.7"	"247.1"	"158.0"	"164.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00401"	"Neural Wiskott-Aldrich syndrome protein OS=Homo sapiens OX=9606 GN=WASL PE=1 SV=2"	"6"	"2"	"3"	"2"	"505"	"54.8"	"7.93"	"298.85"	"7.79"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity"	"Pf00568, Pf00786, Pf02205"	"8976"	"ENSG00000106299"	"WASL"	"A1JUI9; hsa:8976; O00401; Q7Z746"	"Clathrin-mediated endocytosis; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RHO GTPases Activate WASPs and WAVEs; RHOJ GTPase cycle; RHOV GTPase cycle; NOSTRIN mediated eNOS trafficking; Nephrin family interactions; EPHB-mediated forward signaling; DCC mediated attractive signaling"	"Pathogenic Escherichia coli infection; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; Chemokine signaling pathway; G13 signaling pathway"	"17"	"0"	"57.2"	"59.9"	"183.3"	"50.2"	"57.3"	"48.5"	"220.7"	"38.3"	"83.2"	"84.8"	"110.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55265"	"Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4"	"2"	"3"	"6"	"3"	"1226"	"136.0"	"8.65"	"1004.85"	"7.78"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00035, Pf02137, Pf02295"	"103"	"ENSG00000160710"	"ADAR"	"B1AQQ9; B1AQR0; D3DV76; hsa:103; O15223; O43859; O43860; P55265; Q9BYM3; Q9BYM4"	"Interferon alpha/beta signaling; C6 deamination of adenosine; Formation of editosomes by ADAR proteins"	"Measles virus infection; Cytosolic DNA-sensing pathway"	"5"	"0"	"49.0"	"47.1"	"246.3"	"48.8"	"38.5"	"27.9"	"228.4"	"18.6"	"30.0"	"27.8"	"36.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P58546"	"Myotrophin OS=Homo sapiens OX=9606 GN=MTPN PE=1 SV=2"	"13"	"2"	"6"	"2"	"118"	"12.9"	"5.52"	"806.69"	"7.76"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity"	"Pf12796"	"136319"	"ENSG00000105887"	"MTPN"	"hsa:136319; P58546"	""	""	"0"	"0"	"233.9"	"302.4"	"1462.3"	"306.0"	"238.3"	"210.8"	"1847.6"	"157.9"	"216.1"	"177.6"	"156.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N6M0"	"Deubiquitinase OTUD6B OS=Homo sapiens OX=9606 GN=OTUD6B PE=1 SV=1"	"11"	"2"	"3"	"2"	"293"	"33.8"	"6.05"	"258.73"	"7.75"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	""	"other molecular function"	"Pf02338"	"51633"	"ENSG00000155100"	"OTUD6B"	"A8K6I1; B4DEY0; hsa:51633; Q8N6M0; Q9NTA4; Q9Y387"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q02952"	"A-kinase anchor protein 12 OS=Homo sapiens OX=9606 GN=AKAP12 PE=1 SV=4"	"2"	"3"	"6"	"3"	"1782"	"191.4"	"4.41"	"1078.43"	"7.71"	"3"	"3"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf03832, Pf10522"	"9590"	"ENSG00000131016"	"AKAP12"	"hsa:9590; O00310; O00498; Q02952; Q4LE68; Q5SZ80; Q5TGN1; Q68D82; Q99970"	"RHOD GTPase cycle; RHOF GTPase cycle"	"G protein signaling pathways"	"3"	"0"	"52.3"	"47.9"	"149.7"	"67.0"	"51.4"	"49.9"	"163.9"	"17.0"	"35.5"	"31.0"	"18.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00170"	"AH receptor-interacting protein OS=Homo sapiens OX=9606 GN=AIP PE=1 SV=2"	"10"	"2"	"4"	"2"	"330"	"37.6"	"6.29"	"787.43"	"7.70"	"2"	"2"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"23.3"	"34.0"	"111.0"	"34.1"	"40.3"	"38.5"	"120.3"	"21.7"	"30.3"	"31.0"	"20.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49757"	"Protein numb homolog OS=Homo sapiens OX=9606 GN=NUMB PE=1 SV=2"	"5"	"2"	"3"	"2"	"651"	"70.8"	"8.51"	"338.03"	"7.70"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00640, Pf06311"	"8650"	"ENSG00000133961"	"NUMB"	"B1P2N5; B1P2N6; B1P2N7; B1P2N8; B1P2N9; B4E2B1; hsa:8650; P49757; Q6NUQ7; Q86SY1; Q8WW73; Q9UBG1; Q9UEQ4; Q9UKE8; Q9UKE9; Q9UKF0; Q9UQJ4"	"Recycling pathway of L1; Degradation of GLI1 by the proteasome; Hedgehog 'on' state; Activated NOTCH1 Transmits Signal to the Nucleus"	"Notch signaling; VEGFA-VEGFR2 signaling; Head and neck squamous cell carcinoma; Neurogenesis regulation in the olfactory epithelium; TROP2 regulatory signaling; Notch signaling pathway"	"10"	"0"	"30.7"	"37.5"	"109.3"	"27.3"	"29.0"	"26.2"	"143.7"	"57.8"	"134.4"	"179.3"	"261.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14579"	"Coatomer subunit epsilon OS=Homo sapiens OX=9606 GN=COPE PE=1 SV=3"	"10"	"2"	"4"	"2"	"308"	"34.5"	"5.12"	"638.01"	"7.69"	"2"	"2"	"transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus"	"other molecular function"	"Pf04733"	"11316"	"ENSG00000105669"	"COPE"	"A6NE29; A6NKA3; hsa:11316; O14579; O76097; Q6IBB8; Q9UGP6"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport"	""	"2"	"0"	"86.3"	"88.6"	"263.9"	"78.4"	"84.1"	"56.2"	"285.8"	"43.7"	"72.3"	"43.7"	"48.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60228"	"Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1"	"6"	"2"	"4"	"2"	"445"	"52.2"	"6.04"	"808.14"	"7.68"	"2"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01399, Pf09440"	"3646"	"ENSG00000104408"	"EIF3E"	"hsa:3646; O43902; P60228; Q64058; Q64059; Q64252; Q6FG33; Q8WVK4"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"8"	"0"	"77.3"	"73.9"	"224.1"	"69.4"	"63.1"	"62.2"	"250.0"	"27.4"	"49.9"	"66.0"	"63.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5TBB1"	"Ribonuclease H2 subunit B OS=Homo sapiens OX=9606 GN=RNASEH2B PE=1 SV=1"	"13"	"3"	"4"	"3"	"312"	"35.1"	"9.13"	"901.58"	"7.64"	"2"	"2"	"cell cycle OR cell proliferation;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	""	"Pf09468, Pf17745"	"79621"	"ENSG00000136104"	"RNASEH2B"	"G3XAJ1; hsa:79621; Q05DR2; Q5TBB1; Q6PK48; Q9HAF7"	""	""	"0"	"0"	"80.7"	"105.6"	"320.3"	"96.4"	"88.0"	"67.1"	"584.6"	"104.0"	"183.9"	"197.1"	"217.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N806"	"Putative E3 ubiquitin-protein ligase UBR7 OS=Homo sapiens OX=9606 GN=UBR7 PE=1 SV=2"	"5"	"2"	"4"	"2"	"425"	"48.0"	"4.81"	"777.86"	"7.63"	"2"	"2"	"protein metabolism;other metabolic processes"	""	"other molecular function"	"Pf02207"	"55148"	"ENSG00000012963; ENSG00000278787"	"UBR7"	"hsa:55148; Q86U21; Q86UA9; Q8N806; Q96BY0; Q9NVV6"	""	""	"0"	"0"	"109.2"	"130.8"	"414.5"	"125.8"	"122.3"	"113.7"	"450.8"	"75.9"	"121.1"	"101.4"	"90.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P5R6"	"60S ribosomal protein L22-like 1 OS=Homo sapiens OX=9606 GN=RPL22L1 PE=1 SV=2"	"30"	"2"	"3"	"2"	"122"	"14.6"	"9.38"	"459.03"	"7.61"	"1"	"2"	"protein metabolism;other metabolic processes"	"translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01776"	"200916"	"ENSG00000163584"	"RPL22L1"	"hsa:200916; Q32Q77; Q6P5R6"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	""	"13"	"0"	"153.6"	"183.8"	"610.7"	"154.7"	"153.3"	"113.5"	"725.1"	"86.8"	"108.9"	"96.3"	"122.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49903"	"Selenide, water dikinase 1 OS=Homo sapiens OX=9606 GN=SEPHS1 PE=1 SV=2"	"8"	"2"	"3"	"2"	"392"	"42.9"	"5.97"	"335.58"	"7.57"	"1"	"2"	"protein metabolism;other metabolic processes"	"plasma membrane;other membranes;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00586, Pf02769"	"22929"	"ENSG00000086475"	"SEPHS1"	"B4DWK0; D3DRS9; D6PSQ9; hsa:22929; P49903; Q5T5U8; Q5T5U9; Q9BVT4"	""	""	"0"	"0"	"76.7"	"79.3"	"322.2"	"101.4"	"92.9"	"73.1"	"346.1"	"50.2"	"82.5"	"53.6"	"59.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N6N3"	"UPF0690 protein C1orf52 OS=Homo sapiens OX=9606 GN=C1orf52 PE=1 SV=1"	"13"	"2"	"4"	"2"	"182"	"20.6"	"5.21"	"757.22"	"7.55"	"2"	"2"	""	"nucleus"	""	"Pf15559"	"148423"	"ENSG00000162642"	"C1orf52"	"B3KX89; hsa:148423; Q8N6N3; Q8TDK5; Q8TDK6"	""	""	"0"	"0"	"57.3"	"78.2"	"220.5"	"75.0"	"80.4"	"72.4"	"272.5"	"55.9"	"78.5"	"61.4"	"61.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IXI1"	"Mitochondrial Rho GTPase 2 OS=Homo sapiens OX=9606 GN=RHOT2 PE=1 SV=2"	"6"	"3"	"6"	"3"	"618"	"68.1"	"5.86"	"910.25"	"7.51"	"3"	"3"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf00071, Pf08355, Pf08356"	"89941"	"ENSG00000140983"	"RHOT2"	"A2IDC2; hsa:89941; Q8IXI1; Q8NF53; Q96C13; Q96S17; Q9BT60; Q9H7M8"	"RHOT2 GTPase cycle"	""	"1"	"0"	"42.3"	"37.2"	"210.5"	"39.6"	"38.3"	"23.4"	"192.6"	"16.4"	"20.8"	"14.1"	"19.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P15170"	"Eukaryotic peptide chain release factor GTP-binding subunit ERF3A OS=Homo sapiens OX=9606 GN=GSPT1 PE=1 SV=1"	"8"	"4"	"6"	"4"	"499"	"55.7"	"5.62"	"1356.92"	"7.50"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03143, Pf03144"	"2935"	"ENSG00000103342"	"GSPT1"	"hsa:2935; J3KQG6; P15170; Q96GF2"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	""	"4"	"0"	"392.6"	"431.6"	"2130.4"	"411.4"	"300.2"	"234.6"	"1714.5"	"185.8"	"199.6"	"190.9"	"169.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75489"	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS3 PE=1 SV=1"	"17"	"3"	"5"	"3"	"264"	"30.2"	"7.50"	"1551.04"	"7.50"	"3"	"2"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion;nucleus"	"transporter activity;other molecular function"	"Pf00329"	"4722"	"ENSG00000213619; ENSG00000285387"	"NDUFS3"	"B2R9J1; B4DFM8; hsa:4722; O75489; Q9UNQ8"	"Complex I biogenesis; RHOG GTPase cycle"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"6"	"0"	"135.9"	"120.3"	"529.5"	"133.0"	"106.1"	"87.3"	"566.3"	"64.8"	"93.7"	"81.9"	"79.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P29144"	"Tripeptidyl-peptidase 2 OS=Homo sapiens OX=9606 GN=TPP2 PE=1 SV=4"	"3"	"4"	"7"	"4"	"1249"	"138.3"	"6.32"	"1226.26"	"7.45"	"4"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00082, Pf12580"	"7174"	"ENSG00000134900"	"TPP2"	"hsa:7174; P29144; Q5VZU8"	"Antigen processing: Ubiquitination & Proteasome degradation"	""	"1"	"0"	"126.6"	"125.5"	"323.8"	"117.0"	"99.4"	"71.3"	"369.1"	"49.2"	"65.5"	"52.7"	"66.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82970"	"High mobility group nucleosome-binding domain-containing protein 5 OS=Homo sapiens OX=9606 GN=HMGN5 PE=1 SV=1"	"14"	"3"	"5"	"3"	"282"	"31.5"	"4.55"	"1040.37"	"7.43"	"3"	"2"	"cell organization and biogenesis;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01101"	"79366"	"ENSG00000198157"	"HMGN5"	"hsa:79366; P82970; Q5JSL1"	""	""	"0"	"0"	"171.3"	"170.9"	"717.4"	"155.8"	"135.4"	"86.6"	"898.0"	"86.2"	"107.2"	"93.7"	"65.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q08170"	"Serine/arginine-rich splicing factor 4 OS=Homo sapiens OX=9606 GN=SRSF4 PE=1 SV=2"	"5"	"3"	"6"	"1"	"494"	"56.6"	"11.52"	"902.28"	"7.42"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076"	"6429"	"ENSG00000116350"	"SRSF4"	"hsa:6429; Q08170; Q5VXP1; Q9BUA4; Q9UEB5"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"mRNA processing"	"6"	"2"	"415.5"	"443.4"	"1725.9"	"360.8"	"404.8"	"316.0"	"1939.4"	"213.6"	"343.4"	"235.5"	"227.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P587"	"Acylpyruvase FAHD1, mitochondrial OS=Homo sapiens OX=9606 GN=FAHD1 PE=1 SV=2"	"10"	"2"	"4"	"2"	"224"	"24.8"	"7.39"	"825.41"	"7.41"	"2"	"2"	"other metabolic processes"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf01557"	"81889"	"ENSG00000180185"	"FAHD1"	"B1AK40; B1AK41; hsa:81889; Q6FIC7; Q6P587; Q96RY1; Q9H0N6"	"Citric acid cycle (TCA cycle)"	""	"1"	"0"	"102.5"	"145.5"	"364.5"	"140.8"	"139.3"	"111.8"	"634.2"	"184.0"	"280.6"	"278.9"	"406.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UMY4"	"Sorting nexin-12 OS=Homo sapiens OX=9606 GN=SNX12 PE=1 SV=4"	"19"	"2"	"3"	"2"	"162"	"18.9"	"8.44"	"613.21"	"7.39"	"1"	"2"	"transport;other biological processes"	"other membranes;other cytoplasmic organelle"	"other molecular function"	"Pf00787"	"29934"	"ENSG00000147164"	"SNX12"	"F8W8K5; hsa:29934; Q8WUG9; Q9UMY4"	""	""	"0"	"0"	"28.7"	"29.4"	"165.8"	"35.6"	"30.1"	"17.7"	"233.7"	"18.1"	"30.9"	"33.5"	"36.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EI5"	"Transcription elongation factor A protein-like 4 OS=Homo sapiens OX=9606 GN=TCEAL4 PE=1 SV=2"	"13"	"3"	"6"	"3"	"215"	"24.6"	"5.20"	"938.16"	"7.38"	"3"	"3"	""	"nucleus"	""	"Pf04538"	"79921"	"ENSG00000133142"	"TCEAL4"	"hsa:79921; Q8WY12; Q96EI5; Q9H2H1; Q9H775"	""	""	"0"	"0"	"107.0"	"150.3"	"349.4"	"141.3"	"130.9"	"121.1"	"518.1"	"102.6"	"169.8"	"129.4"	"127.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75717"	"WD repeat and HMG-box DNA-binding protein 1 OS=Homo sapiens OX=9606 GN=WDHD1 PE=1 SV=1"	"2"	"2"	"4"	"2"	"1129"	"125.9"	"5.62"	"859.24"	"7.37"	"2"	"2"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400, Pf12341, Pf12894"	"11169"	"ENSG00000198554"	"WDHD1"	"C9JW18; F6W0U7; hsa:11169; O75717"	""	"Mesodermal commitment pathway"	"1"	"0"	"17.7"	"10.8"	"52.2"	"13.6"	"17.6"	"7.6"	"87.4"	"12.7"	"19.7"	"18.0"	"23.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WW12"	"PEST proteolytic signal-containing nuclear protein OS=Homo sapiens OX=9606 GN=PCNP PE=1 SV=2"	"22"	"4"	"6"	"4"	"178"	"18.9"	"7.49"	"1367.68"	"7.35"	"4"	"2"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes"	"nucleus"	""	"Pf15473"	"57092"	"ENSG00000081154"	"PCNP"	"B2RBE7; D3DN52; hsa:57092; Q53GF3; Q6AI44; Q8WW12; Q96CU3; Q9NS81"	""	""	"0"	"0"	"313.3"	"347.1"	"1372.3"	"384.3"	"361.0"	"243.0"	"1893.9"	"198.8"	"314.7"	"234.8"	"186.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q3ZCQ8"	"Mitochondrial import inner membrane translocase subunit TIM50 OS=Homo sapiens OX=9606 GN=TIMM50 PE=1 SV=2"	"11"	"4"	"6"	"4"	"353"	"39.6"	"8.37"	"767.87"	"7.34"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;signal transduction"	"other membranes;mitochondrion;nucleus"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf03031"	"92609"	"ENSG00000105197"	"TIMM50"	"hsa:92609; Q330K1; Q3ZCQ8; Q6QA00; Q96FJ5; Q96GY2; Q9H370"	"Mitochondrial protein import"	""	"1"	"0"	"291.9"	"304.2"	"1025.4"	"282.3"	"245.1"	"193.0"	"1148.9"	"157.5"	"224.1"	"187.4"	"200.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23919"	"Thymidylate kinase OS=Homo sapiens OX=9606 GN=DTYMK PE=1 SV=4"	"11"	"3"	"5"	"3"	"212"	"23.8"	"8.27"	"1191.86"	"7.33"	"3"	"2"	"other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf02223"	"1841"	"ENSG00000168393"	"DTYMK"	"B7ZW70; hsa:1841; P23919; Q6FGX1; Q9BUX4"	"Interconversion of nucleotide di- and triphosphates"	"Pyrimidine metabolism; 2q37 copy number variation syndrome"	"3"	"0"	"57.1"	"67.0"	"266.0"	"57.7"	"64.6"	"50.2"	"315.1"	"61.0"	"64.2"	"65.1"	"80.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H6T3"	"RNA polymerase II-associated protein 3 OS=Homo sapiens OX=9606 GN=RPAP3 PE=1 SV=2"	"6"	"3"	"6"	"3"	"665"	"75.7"	"6.84"	"870.69"	"7.32"	"3"	"3"	"other biological processes"	"cytosol;other cell component"	""	"Pf00515, Pf13176, Pf13181, Pf13877"	"79657"	"ENSG00000005175"	"RPAP3"	"B4DRW9; hsa:79657; Q6PHR5; Q9H6T3"	""	""	"0"	"0"	"68.1"	"58.3"	"205.9"	"61.7"	"66.0"	"58.4"	"184.0"	"28.8"	"53.3"	"51.5"	"73.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00303"	"Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1"	"9"	"3"	"6"	"3"	"357"	"37.5"	"5.45"	"866.39"	"7.32"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01398, Pf13012"	"8665"	"ENSG00000175390"	"EIF3F"	"A8K0S2; hsa:8665; O00303; Q6IB45; Q8N978"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"Translation factors; VEGFA-VEGFR2 signaling; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"9"	"0"	"206.2"	"196.2"	"537.1"	"150.3"	"160.9"	"150.7"	"410.9"	"44.0"	"80.5"	"72.4"	"62.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q00535"	"Cyclin-dependent-like kinase 5 OS=Homo sapiens OX=9606 GN=CDK5 PE=1 SV=3"	"9"	"2"	"6"	"2"	"292"	"33.3"	"7.66"	"905.91"	"7.32"	"2"	"2"	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;kinase activity;other molecular function"	"Pf00069"	"1020"	"ENSG00000164885"	"CDK5"	"A1XKG3; hsa:1020; Q00535"	"NPAS4 regulates expression of target genes; NGF-stimulated transcription; Regulation of TP53 Activity through Phosphorylation; Factors involved in megakaryocyte development and platelet production; CRMPs in Sema3A signaling; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models; DARPP-32 events; Activated NTRK2 signals through CDK5"	"miRNA regulation of DNA damage response; Nicotine effect on dopaminergic neurons; Alzheimer's disease and miRNA effects; Brain-derived neurotrophic factor (BDNF) signaling pathway; ATM signaling in development and disease ; Alzheimer's disease; Neurogenesis regulation in the olfactory epithelium; DNA damage response"	"16"	"0"	"120.9"	"126.9"	"460.1"	"130.5"	"128.6"	"100.4"	"618.3"	"106.6"	"216.5"	"216.5"	"257.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TEX9"	"Importin-4 OS=Homo sapiens OX=9606 GN=IPO4 PE=1 SV=2"	"2"	"2"	"6"	"2"	"1081"	"118.6"	"4.96"	"981.11"	"7.29"	"2"	"2"	"transport;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf02985, Pf03810, Pf13513"	"79711"	"ENSG00000196497; ENSG00000285248"	"IPO4"	"B2RN95; hsa:79711; Q2NL96; Q86TZ9; Q8NCG8; Q8TEX9; Q96SJ3; Q9BTI4; Q9H5L0"	""	""	"0"	"0"	"9.4"	"9.4"	"55.2"	"12.4"	"5.9"	"3.2"	"34.3"	"2.3"	"3.6"	"5.1"	"3.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49756"	"RNA-binding protein 25 OS=Homo sapiens OX=9606 GN=RBM25 PE=1 SV=3"	"4"	"2"	"4"	"2"	"843"	"100.1"	"6.32"	"840.03"	"7.28"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf01480"	"58517"	"ENSG00000119707"	"RBM25"	"A0PJL9; B2RNA8; B3KT03; hsa:58517; P49756; Q2TA72; Q5XJ17; Q6P665; Q9H6A1; Q9UEQ5; Q9UIE9"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"20.5"	"23.7"	"73.8"	"14.5"	"15.5"	"14.0"	"69.7"	"8.9"	"12.9"	"12.8"	"13.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60678"	"Protein arginine N-methyltransferase 3 OS=Homo sapiens OX=9606 GN=PRMT3 PE=1 SV=4"	"8"	"3"	"5"	"3"	"531"	"59.9"	"5.35"	"942.64"	"7.28"	"3"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity;other molecular function"	"Pf06325"	"10196"	"ENSG00000185238"	"PRMT3"	"A0A0A0MSN7; B4DUC7; hsa:10196; O60678"	"RMTs methylate histone arginines; Protein methylation"	"Nitric oxide metabolism in cystic fibrosis"	"3"	"0"	"48.8"	"66.8"	"232.4"	"66.5"	"52.9"	"38.5"	"169.6"	"22.1"	"33.5"	"32.9"	"26.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UPY3"	"Endoribonuclease Dicer OS=Homo sapiens OX=9606 GN=DICER1 PE=1 SV=3"	"1"	"1"	"4"	"1"	"1922"	"218.5"	"5.68"	"830.80"	"7.28"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00271, Pf00636, Pf02170, Pf03368, Pf04851"	"23405"	"ENSG00000100697"	"DICER1"	"A7E2D3; B3KRG4; E0AD28; hsa:23405; O95943; Q9UPY3; Q9UQ02"	"MicroRNA (miRNA) biogenesis; Small interfering RNA (siRNA) biogenesis; tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis"	"miRNA biogenesis; exRNA mechanism of action and biogenesis; Hypoxia-mediated EMT and stemness; mRNA processing; Fragile X syndrome; Influence of laminopathies on Wnt signaling; Overlap between signal transduction pathways contributing to LMNA laminopathies"	"10"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"P46087"	"Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NOP2 PE=1 SV=2"	"3"	"2"	"4"	"2"	"812"	"89.2"	"9.23"	"706.62"	"7.28"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf01189, Pf08062, Pf17125"	"4839"	"ENSG00000111641"	"NOP2"	"A1A4Z3; B3KPD6; hsa:4839; P46087; Q05BA7; Q0P5S5; Q3KQS4; Q58F30"	"rRNA modification in the nucleus and cytosol; TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"	"Imatinib and chronic myeloid leukemia"	"3"	"0"	"122.2"	"115.8"	"365.5"	"119.8"	"133.9"	"110.5"	"538.3"	"157.4"	"267.5"	"210.4"	"238.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y608"	"Leucine-rich repeat flightless-interacting protein 2 OS=Homo sapiens OX=9606 GN=LRRFIP2 PE=1 SV=1"	"4"	"2"	"4"	"2"	"721"	"82.1"	"6.95"	"786.30"	"7.27"	"2"	"2"	"cell-cell signaling;signal transduction;other biological processes"	""	"other molecular function"	"Pf09738"	"9209"	"ENSG00000093167"	"LRRFIP2"	"A8K649; A8MXR0; B4DY63; hsa:9209; Q68CV3; Q9NXH5; Q9Y608"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A4D1P6"	"WD repeat-containing protein 91 OS=Homo sapiens OX=9606 GN=WDR91 PE=1 SV=2"	"5"	"3"	"5"	"3"	"747"	"83.3"	"6.58"	"520.12"	"7.25"	"2"	"3"	"transport;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle"	"enzyme regulator activity"	"Pf00400"	"29062"	"ENSG00000105875"	"WDR91"	"A4D1P6; A6NK54; C9JMI4; hsa:29062; Q6FI65; Q6MZQ1; Q6P4I1; Q96AE5; Q96G63; Q9H062; Q9H9B6; Q9NVG7; Q9NZY6"	"CDC42 GTPase cycle"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"P28331"	"NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS1 PE=1 SV=3"	"4"	"3"	"6"	"3"	"727"	"79.4"	"6.23"	"893.20"	"7.25"	"3"	"3"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00384, Pf09326, Pf10588, Pf13510"	"4719"	"ENSG00000023228; ENSG00000283447"	"NDUFS1"	"B4DIN9; B4DJA0; B4DPG1; B4DUC1; E7ENF3; hsa:4719; P28331; Q53TR8; Q8N1C4; Q8TCC9"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"5"	"0"	"71.4"	"70.5"	"264.9"	"51.5"	"37.6"	"30.6"	"241.7"	"26.1"	"39.9"	"21.9"	"21.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13523"	"Serine/threonine-protein kinase PRP4 homolog OS=Homo sapiens OX=9606 GN=PRPF4B PE=1 SV=3"	"4"	"4"	"7"	"4"	"1007"	"116.9"	"10.26"	"1329.53"	"7.22"	"4"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"8899"	"ENSG00000112739"	"PRPF4B"	"A8K5C9; hsa:8899; Q13523; Q5D0F6; Q5TAY8; Q8IVC3; Q8TDP2; Q96QT7; Q9UEE6"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"0"	"63.7"	"70.1"	"266.0"	"51.6"	"51.7"	"37.3"	"215.6"	"29.4"	"48.4"	"36.5"	"31.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6DKJ4"	"Nucleoredoxin OS=Homo sapiens OX=9606 GN=NXN PE=1 SV=2"	"9"	"2"	"3"	"2"	"435"	"48.4"	"4.97"	"409.56"	"7.20"	"1"	"2"	"cell-cell signaling;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf13848, Pf13905"	"64359"	"ENSG00000167693"	"NXN"	"B4DXQ0; D3DTH2; hsa:64359; Q3SWW6; Q6DKJ4; Q6P3U6; Q7L4C6; Q9H9Q1"	""	""	"0"	"0"	"30.0"	"59.2"	"192.8"	"73.7"	"61.6"	"65.7"	"192.8"	"31.1"	"41.3"	"30.3"	"32.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95861"	"3'(2'),5'-bisphosphate nucleotidase 1 OS=Homo sapiens OX=9606 GN=BPNT1 PE=1 SV=1"	"14"	"2"	"2"	"2"	"308"	"33.4"	"5.69"	""	"7.18"	""	"2"	"other metabolic processes;developmental processes"	"cytosol"	"other molecular function"	"Pf00459"	"10380"	"ENSG00000162813"	"BPNT1"	"A8K7C8; B4DPS5; B4DUS9; D3DTA9; hsa:10380; O95861; Q8WVL5; Q9UGJ3"	"Cytosolic sulfonation of small molecules"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9UBN7"	"Histone deacetylase 6 OS=Homo sapiens OX=9606 GN=HDAC6 PE=1 SV=2"	"3"	"2"	"6"	"2"	"1215"	"131.3"	"5.30"	"892.65"	"7.18"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00850, Pf02148"	"10013"	"ENSG00000094631"	"HDAC6"	"hsa:10013; O94975; Q6NT75; Q7L3E5; Q96CY0; Q9UBN7"	"Cilium Assembly; Aggrephagy; Late endosomal microautophagy; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Transcriptional regulation by RUNX2; NOTCH1 Intracellular Domain Regulates Transcription; Notch-HLH transcription pathway; RUNX2 regulates osteoblast differentiation; Chaperone Mediated Autophagy; HSF1 activation"	"Neural crest differentiation; Ectoderm differentiation; Ectoderm differentiation; Ethanol effects on histone modifications; 7q11.23 copy number variation syndrome"	"16"	"0"	"46.3"	"42.3"	"75.2"	"51.0"	"41.1"	"46.2"	"62.0"	"18.8"	"28.2"	"17.4"	"24.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15436"	"Protein transport protein Sec23A OS=Homo sapiens OX=9606 GN=SEC23A PE=1 SV=2"	"5"	"2"	"3"	"2"	"765"	"86.1"	"7.08"	"469.98"	"7.18"	"1"	"2"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00626, Pf04810, Pf04811, Pf04815, Pf08033"	"10484"	"ENSG00000100934"	"SEC23A"	"B2R5P4; B3KXI2; hsa:10484; Q15436; Q8NE16"	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC; MHC class II antigen presentation; SARS-CoV-2 activates/modulates innate and adaptive immune responses; COPII-mediated vesicle transport; Cargo concentration in the ER; Regulation of cholesterol biosynthesis by SREBP (SREBF)"	"Sterol regulatory element-binding proteins (SREBP) signaling"	"7"	"0"	"41.4"	"40.9"	"172.0"	"31.3"	"21.0"	"21.3"	"64.5"	"13.2"	"15.8"	"13.4"	"14.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H9A6"	"Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1"	"4"	"3"	"5"	"3"	"602"	"68.2"	"6.43"	"507.74"	"7.16"	"2"	"3"	""	""	""	"Pf00560, Pf13855"	"55631"	"ENSG00000066557"	"LRRC40"	"hsa:55631; Q9BTR7; Q9H9A6; Q9NSK1; Q9NXC1"	""	""	"0"	"0"	"49.8"	"61.6"	"391.0"	"62.3"	"25.3"	"29.5"	"363.0"	"18.6"	"10.3"	"27.4"	"31.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09496"	"Clathrin light chain A OS=Homo sapiens OX=9606 GN=CLTA PE=1 SV=1"	"13"	"4"	"7"	"4"	"248"	"27.1"	"4.51"	"1184.80"	"7.16"	"4"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01086"	"1211"	"ENSG00000122705"	"CLTA"	"A8K4W3; B4DIN1; F5H6N3; hsa:1211; P09496; Q2XPN5; Q53XZ1"	"MHC class II antigen presentation; Recycling pathway of L1; Lysosome Vesicle Biogenesis; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; LDL clearance; Retrograde neurotrophin signalling; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; VLDLR internalisation and degradation; Entry of Influenza Virion into Host Cell via Endocytosis; Formation of annular gap junctions"	"Synaptic vesicle pathway; Ebola virus infection in host; Fragile X syndrome"	"17"	"0"	"512.3"	"518.2"	"1582.9"	"581.5"	"484.6"	"416.0"	"1888.7"	"270.0"	"422.7"	"305.3"	"312.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q06323"	"Proteasome activator complex subunit 1 OS=Homo sapiens OX=9606 GN=PSME1 PE=1 SV=1"	"16"	"4"	"6"	"4"	"249"	"28.7"	"6.02"	"1582.51"	"7.15"	"4"	"2"	"other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf02251, Pf02252"	"5720"	"ENSG00000092010; ENSG00000284916"	"PSME1"	"A6NJG9; H0YNE3; hsa:5720; Q06323; Q6IBM2; Q9UEF4"	"Regulation of expression of SLITs and ROBOs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation"	"60"	"0"	"266.4"	"311.0"	"1237.8"	"297.3"	"275.4"	"240.0"	"1749.4"	"186.4"	"285.9"	"235.2"	"202.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22570"	"NADPH:adrenodoxin oxidoreductase, mitochondrial OS=Homo sapiens OX=9606 GN=FDXR PE=1 SV=3"	"7"	"2"	"3"	"2"	"491"	"53.8"	"8.44"	"301.91"	"7.14"	"1"	"2"	"other metabolic processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf07992"	"2232"	"ENSG00000161513"	"FDXR"	"B4DDI7; B4DHX5; B4DQQ4; B4DX24; B7Z7G2; E7EQC1; hsa:2232; P22570; Q13716; Q4PJI0; Q9BU12"	"Endogenous sterols; Pregnenolone biosynthesis; Defective CYP11A1 causes AICSR; Electron transport from NADPH to Ferredoxin"	"Iron-sulfur cluster biogenesis"	"5"	"0"	"46.0"	"42.2"	"145.6"	"53.9"	"57.6"	"51.1"	"232.5"	"36.2"	"63.1"	"69.8"	"136.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00178"	"GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=GTPBP1 PE=1 SV=3"	"5"	"2"	"3"	"2"	"669"	"72.4"	"8.34"	"246.50"	"7.13"	"1"	"2"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;other cytoplasmic organelle"	"nucleic acid binding activity;other molecular function"	"Pf00009"	"9567"	"ENSG00000100226"	"GTPBP1"	"hsa:9567; O00178; Q6IC67"	""	""	"0"	"0"	"20.5"	"19.1"	"86.7"	"23.3"	"21.6"	"13.8"	"114.9"	"11.5"	"11.1"	"10.1"	"11.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25325"	"3-mercaptopyruvate sulfurtransferase OS=Homo sapiens OX=9606 GN=MPST PE=1 SV=3"	"9"	"2"	"4"	"2"	"297"	"33.2"	"6.60"	"820.16"	"7.12"	"2"	"2"	"other metabolic processes;developmental processes;other biological processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00581"	"4357"	"ENSG00000128309"	"MPST"	"A8MZ34; B3KP52; hsa:4357; J3KPV7; O75750; P25325; Q6FHN9"	"Degradation of cysteine and homocysteine"	"Trans-sulfuration pathway; Amino acid metabolism"	"3"	"0"	"30.8"	"35.2"	"154.3"	"35.6"	"39.2"	"19.7"	"181.2"	"25.4"	"27.6"	"24.7"	"33.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q53GQ0"	"Very-long-chain 3-oxoacyl-CoA reductase OS=Homo sapiens OX=9606 GN=HSD17B12 PE=1 SV=2"	"6"	"2"	"4"	"2"	"312"	"34.3"	"9.32"	"762.54"	"7.12"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"extracellular matrix;other membranes;ER/Golgi"	"other molecular function"	"Pf00106"	"51144"	"ENSG00000149084"	"HSD17B12"	"A8K9B0; D3DR23; hsa:51144; Q53GQ0; Q96EA9; Q96JU2; Q9Y6G8"	"Synthesis of very long-chain fatty acyl-CoAs; Androgen biosynthesis"	"Mitochondrial fatty acid synthesis pathway"	"3"	"0"	"257.4"	"209.7"	"955.7"	"242.8"	"222.8"	"162.8"	"782.9"	"86.4"	"159.6"	"107.7"	"118.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3Y2"	"Chromatin target of PRMT1 protein OS=Homo sapiens OX=9606 GN=CHTOP PE=1 SV=2"	"12"	"2"	"4"	"2"	"248"	"26.4"	"12.23"	"811.38"	"7.09"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf13865"	"26097"	"ENSG00000160679"	"CHTOP"	"D3DV55; hsa:26097; Q0VAQ8; Q2VPI9; Q5T7Y8; Q5T7Y9; Q5T7Z0; Q6NSM4; Q6PB28; Q8WYT9; Q9BUC5; Q9H034; Q9H2L0; Q9Y3Y2"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript"	""	"3"	"0"	"41.6"	"42.9"	"150.8"	"37.3"	"39.5"	"28.0"	"208.1"	"18.2"	"29.6"	"23.6"	"20.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3A5"	"Ribosome maturation protein SBDS OS=Homo sapiens OX=9606 GN=SBDS PE=1 SV=4"	"11"	"3"	"5"	"3"	"250"	"28.7"	"8.75"	"1067.12"	"7.08"	"3"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;translation activity;nucleic acid binding activity"	"Pf01172, Pf09377, Pf20268"	"51119"	"ENSG00000126524"	"SBDS"	"A8K0P4; hsa:51119; Q96FX0; Q9NV53; Q9Y3A5"	""	"Genetic causes of porto-sinusoidal vascular disease"	"1"	"0"	"209.6"	"215.5"	"658.7"	"207.0"	"197.8"	"143.0"	"665.2"	"179.2"	"269.7"	"333.7"	"553.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14859"	"POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2"	"5"	"2"	"3"	"2"	"743"	"76.4"	"6.81"	"406.23"	"7.08"	"1"	"2"	"RNA metabolism OR transcription;other biological processes"	"ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00046, Pf00157, Pf19536"	"5451"	"ENSG00000143190"	"POU2F1"	"B1AL91; B1AL93; B4E029; hsa:5451; J3KP77; P14859; Q5TBT7; Q6PK46; Q8NEU9; Q9BPV1"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 3 Promoter; RNA polymerase II transcribes snRNA genes; Estrogen-dependent gene expression; Interleukin-4 and Interleukin-13 signaling"	"Integrated cancer pathway"	"6"	"0"	"18.8"	"16.6"	"51.3"	"9.1"	"15.4"	"17.6"	"59.9"	"5.3"	"18.5"	"14.1"	"15.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05386"	"60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1"	"34"	"3"	"6"	"2"	"114"	"11.5"	"4.32"	"1485.67"	"7.04"	"3"	"2"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00428"	"6176"	"ENSG00000137818"	"RPLP1"	"A6NIB2; hsa:6176; P05386"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"844.8"	"873.6"	"3776.3"	"801.9"	"575.9"	"555.3"	"2594.9"	"128.8"	"190.7"	"150.9"	"118.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P48735"	"Isocitrate dehydrogenase [NADP], mitochondrial OS=Homo sapiens OX=9606 GN=IDH2 PE=1 SV=2"	"8"	"4"	"6"	"4"	"452"	"50.9"	"8.69"	"1239.09"	"7.04"	"4"	"2"	"other metabolic processes"	"cytosol;mitochondrion;other cytoplasmic organelle"	"other molecular function"	"Pf00180"	"3418"	"ENSG00000182054"	"IDH2"	"B2R6L6; B4DFL2; hsa:3418; P48735; Q96GT3"	"Transcriptional activation of mitochondrial biogenesis; Citric acid cycle (TCA cycle)"	"VEGFA-VEGFR2 signaling; Metabolic reprogramming in colon cancer; Cerebral organic acidurias, including diseases; TCA cycle (aka Krebs or citric acid cycle)"	"6"	"0"	"263.1"	"259.8"	"904.9"	"219.6"	"165.6"	"134.9"	"803.1"	"158.4"	"206.2"	"231.0"	"231.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBW8"	"COP9 signalosome complex subunit 7a OS=Homo sapiens OX=9606 GN=COPS7A PE=1 SV=1"	"9"	"2"	"3"	"2"	"275"	"30.3"	"8.22"	"489.48"	"7.03"	"1"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf01399, Pf18392"	"50813"	"ENSG00000111652"	"COPS7A"	"A8K9A6; hsa:50813; Q9NVX3; Q9UBW8; Q9UJW4"	"Cargo recognition for clathrin-mediated endocytosis; Neddylation; Formation of TC-NER Pre-Incision Complex; DNA Damage Recognition in GG-NER"	"Ciliary landscape"	"5"	"0"	"30.0"	"33.6"	"98.7"	"26.9"	"25.5"	"19.3"	"103.5"	"14.3"	"22.2"	"15.9"	"22.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NZB2"	"Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens OX=9606 GN=FAM120A PE=1 SV=2"	"3"	"2"	"3"	"2"	"1118"	"121.8"	"8.88"	"259.12"	"7.03"	"1"	"2"	""	"plasma membrane;other membranes;cytosol;nucleus"	""	""	"23196"	"ENSG00000048828"	"FAM120A"	"A6NGU0; C4AMC6; hsa:23196; O60649; Q14688; Q4VXF4; Q4VXF5; Q4VXG2; Q86V69; Q96I21; Q9NZB1; Q9NZB2"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"98.9"	"109.5"	"313.4"	"94.7"	"92.9"	"72.0"	"360.7"	"61.2"	"68.9"	"54.0"	"67.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P016"	"Thymocyte nuclear protein 1 OS=Homo sapiens OX=9606 GN=THYN1 PE=1 SV=1"	"9"	"2"	"4"	"2"	"225"	"25.7"	"9.25"	"743.70"	"7.00"	"2"	"2"	""	""	""	"Pf01878"	"29087"	"ENSG00000151500"	"THYN1"	"hsa:29087; Q567Q2; Q9H3L4; Q9HC20; Q9P016"	""	""	"0"	"0"	"45.0"	"51.4"	"148.5"	"44.1"	"43.9"	"31.6"	"261.9"	"67.9"	"90.9"	"72.9"	"82.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14550"	"Aldo-keto reductase family 1 member A1 OS=Homo sapiens OX=9606 GN=AKR1A1 PE=1 SV=3"	"10"	"3"	"6"	"2"	"325"	"36.6"	"6.79"	"889.36"	"7.00"	"3"	"3"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00248"	"10327"	"ENSG00000117448"	"AKR1A1"	"A8KAL8; D3DQ04; hsa:10327; P14550; Q6IAZ4"	"Glutathione conjugation; Formation of xylulose-5-phosphate"	"Benzo(a)pyrene metabolism; Metapathway biotransformation Phase I and II"	"4"	"0"	"17.7"	"15.2"	"100.3"	"22.4"	"15.1"	"13.6"	"126.5"	"9.5"	"14.2"	"10.7"	"5.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12972"	"Nuclear inhibitor of protein phosphatase 1 OS=Homo sapiens OX=9606 GN=PPP1R8 PE=1 SV=2"	"11"	"2"	"3"	"2"	"351"	"38.5"	"7.37"	"259.30"	"6.99"	"1"	"2"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00498"	"5511"	"ENSG00000117751"	"PPP1R8"	"hsa:5511; Q12972; Q5TEJ2; Q5TEJ4; Q5TIF2; Q6PKF6; Q9UBH1; Q9UBZ0"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"57.7"	"68.1"	"161.8"	"83.7"	"80.5"	"66.4"	"184.2"	"49.2"	"69.3"	"61.7"	"63.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95239"	"Chromosome-associated kinesin KIF4A OS=Homo sapiens OX=9606 GN=KIF4A PE=1 SV=3"	"3"	"4"	"7"	"4"	"1232"	"139.8"	"6.27"	"1025.66"	"6.99"	"4"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00225"	"24137"	"ENSG00000090889"	"KIF4A"	"B2R7V5; D3DVU4; hsa:24137; O95239; Q86TN3; Q86XX7; Q9NNY6; Q9NY24; Q9UMW3"	"Recycling pathway of L1; COPI-dependent Golgi-to-ER retrograde traffic; MHC class II antigen presentation; Kinesins"	"Retinoblastoma gene in cancer"	"5"	"0"	"132.6"	"95.7"	"167.0"	"42.6"	"60.4"	"38.3"	"122.8"	"23.6"	"28.5"	"36.3"	"27.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UQB8"	"Brain-specific angiogenesis inhibitor 1-associated protein 2 OS=Homo sapiens OX=9606 GN=BAIAP2 PE=1 SV=1"	"4"	"2"	"4"	"2"	"552"	"60.8"	"8.90"	"853.38"	"6.97"	"2"	"2"	"cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf07653, Pf08397"	"10458"	"ENSG00000175866"	"BAIAP2"	"hsa:10458; O43858; Q53HB1; Q86WC1; Q8N5C0; Q96CR7; Q9UBR3; Q9UQ43; Q9UQB8"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; CDC42 GTPase cycle; RAC1 GTPase cycle; RHO GTPases Activate WASPs and WAVEs; RAC3 GTPase cycle; VEGFA-VEGFR2 Pathway"	"Regulation of actin cytoskeleton"	"8"	"0"	"117.4"	"110.9"	"247.2"	"92.9"	"97.4"	"80.0"	"342.2"	"143.6"	"193.1"	"302.5"	"379.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13889"	"General transcription factor IIH subunit 3 OS=Homo sapiens OX=9606 GN=GTF2H3 PE=1 SV=2"	"13"	"2"	"3"	"2"	"308"	"34.4"	"7.02"	"371.80"	"6.93"	"1"	"2"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf03850"	"2967"	"ENSG00000111358"	"GTF2H3"	"B2R819; B4DNZ6; hsa:2967; Q13889; Q7L0G0; Q96AT7"	"NoRC negatively regulates rRNA expression; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Dual Incision in GG-NER"	"Eukaryotic transcription initiation; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; 11p11.2 copy number variation syndrome"	"34"	"0"	"15.9"	"14.3"	"58.2"	"6.9"	"15.3"	"10.5"	"50.3"	"22.5"	"46.0"	"28.5"	"27.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09001"	"39S ribosomal protein L3, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL3 PE=1 SV=1"	"7"	"3"	"6"	"3"	"348"	"38.6"	"9.48"	"948.66"	"6.93"	"3"	"3"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00297"	"11222"	"ENSG00000114686"	"MRPL3"	"hsa:11222; P09001; Q6IBT2"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"370.4"	"378.8"	"1177.2"	"381.6"	"286.4"	"258.8"	"1203.3"	"179.0"	"254.8"	"205.8"	"241.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15145"	"Actin-related protein 2/3 complex subunit 3 OS=Homo sapiens OX=9606 GN=ARPC3 PE=1 SV=3"	"13"	"2"	"4"	"2"	"178"	"20.5"	"8.59"	"863.43"	"6.91"	"2"	"2"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf04062"	"10094"	"ENSG00000111229"	"ARPC3"	"hsa:10094; O00554; O15145"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Clathrin-mediated endocytosis; EPHB-mediated forward signaling"	"Pathogenic Escherichia coli infection"	"6"	"0"	"83.0"	"88.9"	"247.0"	"65.9"	"49.2"	"41.6"	"218.8"	"76.6"	"178.8"	"400.7"	"714.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BS26"	"Endoplasmic reticulum resident protein 44 OS=Homo sapiens OX=9606 GN=ERP44 PE=1 SV=1"	"9"	"4"	"6"	"3"	"406"	"46.9"	"5.26"	"1365.08"	"6.90"	"4"	"2"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf00085, Pf13848"	"23071"	"ENSG00000023318"	"ERP44"	"hsa:23071; O60319; Q4VXC1; Q5VWZ7; Q6UW14; Q8WX67; Q9BS26"	"Neutrophil degranulation"	""	"1"	"1"	"126.4"	"169.9"	"509.3"	"157.3"	"158.7"	"153.3"	"574.1"	"138.1"	"334.2"	"215.0"	"247.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15003"	"Condensin complex subunit 2 OS=Homo sapiens OX=9606 GN=NCAPH PE=1 SV=3"	"3"	"2"	"5"	"2"	"741"	"82.5"	"5.06"	"478.68"	"6.89"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf05786"	"23397"	"ENSG00000121152"	"NCAPH"	"B4E189; hsa:23397; Q15003; Q8TB87"	"Condensation of Prometaphase Chromosomes"	"2q11.2 copy number variation syndrome"	"2"	"0"	"44.7"	"49.0"	"146.2"	"49.2"	"42.5"	"27.7"	"120.6"	"20.1"	"21.2"	"23.8"	"19.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30405"	"Peptidyl-prolyl cis-trans isomerase F, mitochondrial OS=Homo sapiens OX=9606 GN=PPIF PE=1 SV=1"	"26"	"6"	"9"	"5"	"207"	"22.0"	"9.38"	"2272.30"	"6.88"	"6"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"other membranes;mitochondrion;other cell component"	"other molecular function"	"Pf00160"	"10105"	"ENSG00000108179"	"PPIF"	"hsa:10105; P30405; Q2YDB7; Q5W131"	""	"Alzheimer's disease and miRNA effects; Alzheimer's disease"	"2"	"0"	"572.6"	"620.1"	"2430.8"	"599.2"	"609.6"	"571.7"	"3492.1"	"539.7"	"994.2"	"649.4"	"957.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15067"	"Phosphoribosylformylglycinamidine synthase OS=Homo sapiens OX=9606 GN=PFAS PE=1 SV=4"	"2"	"2"	"4"	"2"	"1338"	"144.6"	"5.76"	"569.74"	"6.88"	"2"	"2"	"other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf02769, Pf13507, Pf18072, Pf18076"	"5198"	"ENSG00000178921"	"PFAS"	"A6H8V8; hsa:5198; O15067"	"Purine ribonucleoside monophosphate biosynthesis"	""	"1"	"0"	"78.1"	"89.0"	"275.2"	"72.4"	"83.5"	"63.3"	"364.3"	"64.1"	"80.7"	"76.0"	"65.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61964"	"WD repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=WDR5 PE=1 SV=1"	"7"	"2"	"4"	"2"	"334"	"36.6"	"8.27"	"579.73"	"6.87"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00400"	"11091"	"ENSG00000196363"	"WDR5"	"hsa:11091; P61964; Q91VA5; Q9NWX7; Q9UGP9"	"Neddylation; Formation of WDR5-containing histone-modifying complexes; Activation of anterior HOX genes in hindbrain development during early embryogenesis; RMTs methylate histone arginines; PKMTs methylate histone lysines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; HATs acetylate histones; Cardiogenesis"	"Pleural mesothelioma; Kleefstra syndrome"	"10"	"0"	"54.7"	"56.8"	"223.4"	"53.4"	"53.1"	"40.3"	"273.5"	"51.3"	"74.2"	"70.2"	"70.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96ST2"	"Protein IWS1 homolog OS=Homo sapiens OX=9606 GN=IWS1 PE=1 SV=2"	"4"	"2"	"3"	"2"	"819"	"91.9"	"4.69"	"421.22"	"6.87"	"1"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus"	""	"Pf08711"	"55677"	"ENSG00000163166"	"IWS1"	"hsa:55677; Q2TB65; Q6P157; Q8N3E8; Q96MI7; Q96ST2; Q9NV97; Q9NWH8"	"Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events"	""	"3"	"0"	"49.5"	"62.7"	"138.4"	"58.7"	"50.3"	"49.2"	"209.9"	"60.9"	"69.0"	"55.6"	"63.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q4G0J3"	"La-related protein 7 OS=Homo sapiens OX=9606 GN=LARP7 PE=1 SV=1"	"4"	"2"	"3"	"2"	"582"	"66.9"	"9.55"	"502.48"	"6.87"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf05383, Pf08777"	"51574"	"ENSG00000174720"	"LARP7"	"B2ZHN6; hsa:51574; Q3B7A9; Q4G0J3; Q9P1S7; Q9Y3Z8"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"37.4"	"32.0"	"123.0"	"41.4"	"31.9"	"27.1"	"143.3"	"20.6"	"25.7"	"26.4"	"23.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60343"	"TBC1 domain family member 4 OS=Homo sapiens OX=9606 GN=TBC1D4 PE=1 SV=2"	"2"	"3"	"5"	"3"	"1298"	"146.5"	"7.01"	"1039.65"	"6.86"	"3"	"2"	"transport;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity"	"Pf00566, Pf00640, Pf11830"	"9882"	"ENSG00000136111"	"TBC1D4"	"A7E2X8; B4DU25; B4E235; B6ETN8; B6ETN9; hsa:9882; O60343; Q5W0B9; Q68D14"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"	"Ciliary landscape; Thyroid hormones production and peripheral downstream signaling effects; Insulin signaling"	"4"	"0"	"87.3"	"94.0"	"419.3"	"87.1"	"65.3"	"55.9"	"468.3"	"53.3"	"74.0"	"58.4"	"54.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61088"	"Ubiquitin-conjugating enzyme E2 N OS=Homo sapiens OX=9606 GN=UBE2N PE=1 SV=1"	"26"	"2"	"3"	"2"	"152"	"17.1"	"6.57"	"420.63"	"6.85"	"1"	"2"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00179"	"7334"	"ENSG00000177889"	"UBE2N"	"hsa:7334; P61088; Q16781; Q53Y81"	"ISG15 antiviral mechanism; FCERI mediated NF-kB activation; Downstream TCR signaling; E3 ubiquitin ligases ubiquitinate target proteins; Antigen processing: Ubiquitination & Proteasome degradation; CLEC7A (Dectin-1) signaling; Aggrephagy; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; IKK complex recruitment mediated by RIP1; JNK (c-Jun kinases) phosphorylation and  activation mediated by activated human TAK1; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; NOD1/2 Signaling Pathway; TICAM1, RIP1-mediated IKK complex recruitment; TAK1-dependent IKK and NF-kappa-B activation  ; IRAK1 recruits IKK complex; IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation; activated TAK1 mediates p38 MAPK activation; Nonhomologous End-Joining (NHEJ); Formation of Incision Complex in GG-NER; TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling"	"IL-1 signaling pathway; Interleukin-1 induced activation of NF-kB; MYD88 distinct input-output pathway; Prader-Willi and Angelman syndrome; 3q29 copy number variation syndrome"	"28"	"0"	"51.8"	"45.1"	"240.3"	"44.0"	"30.3"	"24.9"	"251.7"	"28.2"	"35.5"	"28.7"	"26.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NXW9"	"Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 OS=Homo sapiens OX=9606 GN=ALKBH4 PE=1 SV=1"	"14"	"3"	"3"	"3"	"302"	"33.8"	"6.67"	""	"6.83"	""	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"cytoskeletal activity;other molecular function"	""	"54784"	"ENSG00000160993"	"ALKBH4"	"hsa:54784; Q53H92; Q9H6A4; Q9NXW9"	""	""	"0"	"0"	"96.9"	"104.3"	"266.8"	"128.0"	"121.3"	"115.1"	"337.3"	"89.0"	"288.9"	"524.9"	"878.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKE5"	"TRAF2 and NCK-interacting protein kinase OS=Homo sapiens OX=9606 GN=TNIK PE=1 SV=1"	"2"	"2"	"4"	"1"	"1360"	"154.8"	"7.17"	"325.17"	"6.82"	"1"	"2"	"cell-cell signaling;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00780"	"23043"	"ENSG00000154310"	"TNIK"	"A7E2A3; A8K4U1; D3DNQ6; hsa:23043; O60298; Q8WUY7; Q9UKD8; Q9UKD9; Q9UKE0; Q9UKE1; Q9UKE2; Q9UKE3; Q9UKE4; Q9UKE5"	"Oxidative Stress Induced Senescence"	"Hippo-YAP signaling; Pleural mesothelioma"	"3"	"1"	"88.5"	"87.0"	"302.1"	"113.4"	"100.8"	"87.7"	"522.4"	"89.7"	"152.7"	"216.2"	"326.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y450"	"HBS1-like protein OS=Homo sapiens OX=9606 GN=HBS1L PE=1 SV=1"	"4"	"2"	"4"	"2"	"684"	"75.4"	"6.61"	"806.46"	"6.82"	"2"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03143, Pf03144, Pf08938"	"10767"	"ENSG00000112339"	"HBS1L"	"B7Z365; hsa:10767; Q4VX89; Q4VX90; Q5T7G3; Q8NDW9; Q9UPW3; Q9Y450"	"mRNA decay by 3' to 5' exoribonuclease"	"10q11.21q11.23 copy number variation syndrome"	"2"	"0"	"35.0"	"39.6"	"116.0"	"29.7"	"35.9"	"25.0"	"93.5"	"31.6"	"64.4"	"102.8"	"106.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UHY7"	"Enolase-phosphatase E1 OS=Homo sapiens OX=9606 GN=ENOPH1 PE=1 SV=1"	"13"	"2"	"3"	"2"	"261"	"28.9"	"4.78"	"236.82"	"6.81"	"1"	"2"	"other metabolic processes"	"cytosol;nucleus"	"other molecular function"	""	"58478"	"ENSG00000145293"	"ENOPH1"	"hsa:58478; Q7Z4C5; Q9BVC2; Q9UHY7"	"Methionine salvage pathway"	"Methionine de novo and salvage pathway"	"2"	"0"	"26.4"	"22.0"	"108.7"	"28.2"	"19.4"	"13.3"	"118.4"	"8.9"	"18.4"	"10.0"	"12.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14854"	"Cytochrome c oxidase subunit 6B1 OS=Homo sapiens OX=9606 GN=COX6B1 PE=1 SV=2"	"17"	"1"	"4"	"1"	"86"	"10.2"	"7.05"	"731.39"	"6.80"	"1"	"1"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf02297"	"1340"	"ENSG00000126267"	"COX6B1"	"B2R5C9; hsa:1340; P14854; Q6IBL4"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex IV assembly"	"6"	"0"	"55.8"	"71.0"	"292.7"	"97.0"	"96.9"	"74.9"	"390.6"	"67.1"	"94.0"	"67.2"	"63.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NT62"	"Ubiquitin-like-conjugating enzyme ATG3 OS=Homo sapiens OX=9606 GN=ATG3 PE=1 SV=1"	"9"	"2"	"4"	"2"	"314"	"35.8"	"4.74"	"1017.47"	"6.77"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf03987"	"64422"	"ENSG00000144848"	"ATG3"	"hsa:64422; Q6PKC5; Q9H6L9; Q9NT62"	"Macroautophagy"	"Nanoparticle triggered autophagic cell death; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Autophagy; Clock-controlled autophagy in bone metabolism"	"5"	"0"	"100.1"	"98.9"	"432.4"	"89.1"	"92.0"	"62.5"	"593.4"	"69.4"	"75.6"	"63.6"	"54.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22307"	"Non-specific lipid-transfer protein OS=Homo sapiens OX=9606 GN=SCP2 PE=1 SV=2"	"4"	"3"	"5"	"3"	"547"	"59.0"	"6.89"	"1044.61"	"6.76"	"3"	"2"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"cytosol;mitochondrion;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;transporter activity;other molecular function"	"Pf00108, Pf02036, Pf02803"	"6342"	"ENSG00000116171"	"SCP2"	"A6NM69; B4DGJ9; B4DHP6; C9JC79; D3DQ37; E1B6W5; F2Z3J1; hsa:6342; P22307; Q15432; Q16622; Q5VVZ1; Q6NXF4; Q99430"	"TYSND1 cleaves peroxisomal proteins; alpha-linolenic acid (ALA) metabolism"	"PPAR-alpha pathway; Nuclear receptors meta-pathway; Mitochondrial long chain fatty acid beta-oxidation; PPAR signaling pathway; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Mitochondrial fatty acid oxidation disorders; DNA damage response (only ATM dependent)"	"10"	"0"	"229.6"	"254.3"	"1390.7"	"254.1"	"201.4"	"133.1"	"1391.7"	"121.3"	"124.6"	"122.1"	"124.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NP97"	"Dynein light chain roadblock-type 1 OS=Homo sapiens OX=9606 GN=DYNLRB1 PE=1 SV=3"	"40"	"3"	"4"	"3"	"96"	"10.9"	"7.25"	"1014.83"	"6.75"	"2"	"2"	"other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03259"	"83658"	"ENSG00000125971"	"DYNLRB1"	"B1AKR5; hsa:83658; Q5TC72; Q96IV3; Q9NP97; Q9NQM2"	"Intraflagellar transport"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein; 3q29 copy number variation syndrome"	"4"	"0"	"148.9"	"193.9"	"482.6"	"174.9"	"189.4"	"161.4"	"553.1"	"109.7"	"158.1"	"132.8"	"120.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BY77"	"Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2"	"6"	"2"	"4"	"2"	"421"	"46.1"	"9.99"	"639.67"	"6.74"	"2"	"2"	"other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"84271"	"ENSG00000100227"	"POLDIP3"	"A8K6F8; A8K6V9; hsa:84271; Q009A7; Q5H972; Q6PGN6; Q7Z6Z0; Q9BY77; Q9NSP5; Q9NSP6"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	""	"3"	"0"	"72.6"	"75.1"	"254.2"	"88.2"	"87.7"	"61.1"	"380.0"	"78.9"	"128.5"	"94.3"	"95.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UH65"	"Switch-associated protein 70 OS=Homo sapiens OX=9606 GN=SWAP70 PE=1 SV=1"	"4"	"2"	"4"	"2"	"585"	"69.0"	"5.87"	"780.04"	"6.74"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00169"	"23075"	"ENSG00000133789"	"SWAP70"	"D3DQV1; hsa:23075; O75135; Q7LCY6; Q9P061; Q9P0Z8; Q9UH65"	"RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle"	""	"3"	"0"	"36.4"	"47.0"	"164.1"	"46.8"	"37.6"	"38.3"	"161.3"	"23.4"	"85.8"	"187.9"	"283.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P161"	"39S ribosomal protein L54, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL54 PE=1 SV=1"	"26"	"2"	"3"	"2"	"138"	"15.8"	"9.60"	"305.80"	"6.74"	"1"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf08561"	"116541"	"ENSG00000183617"	"MRPL54"	"hsa:116541; Q6P161"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"205.6"	"129.3"	"337.8"	"118.5"	"102.3"	"82.4"	"340.7"	"59.6"	"105.8"	"90.3"	"96.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61020"	"Ras-related protein Rab-5B OS=Homo sapiens OX=9606 GN=RAB5B PE=1 SV=1"	"12"	"2"	"4"	"1"	"215"	"23.7"	"8.13"	"707.24"	"6.74"	"2"	"2"	"cell organization and biogenesis;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00071"	"5869"	"ENSG00000111540"	"RAB5B"	"A8K982; B4DKD7; hsa:5869; P35239; P35277; P61020; Q6PIK9; Q86TH0; Q8IXL2"	"Neutrophil degranulation; Clathrin-mediated endocytosis; RAB GEFs exchange GTP for GDP on RABs; RAB geranylgeranylation; TBC/RABGAPs"	"Ras signaling; Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells"	"7"	"0"	"27.9"	"21.3"	"132.5"	"34.7"	"25.2"	"20.9"	"158.1"	"11.7"	"17.8"	"27.3"	"18.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5TDH0"	"Protein DDI1 homolog 2 OS=Homo sapiens OX=9606 GN=DDI2 PE=1 SV=1"	"6"	"2"	"4"	"2"	"399"	"44.5"	"5.05"	"683.95"	"6.73"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00240, Pf09668"	"84301"	"ENSG00000197312"	"DDI2"	"A8KAE1; hsa:84301; Q5TDH0; Q7RTZ0; Q9BRT1"	""	""	"0"	"0"	"124.7"	"156.2"	"390.5"	"141.0"	"134.5"	"124.2"	"467.6"	"97.8"	"118.5"	"94.6"	"105.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P56385"	"ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2"	"32"	"2"	"4"	"2"	"69"	"7.9"	"9.35"	"680.78"	"6.72"	"2"	"2"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf05680"	"521"	"ENSG00000169020"	"ATP5ME"	"hsa:521; P56385; Q0D2L9"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"Electron transport chain: OXPHOS system in mitochondria; Oxidative phosphorylation"	"4"	"0"	"119.9"	"133.3"	"357.5"	"115.1"	"139.3"	"93.2"	"514.3"	"199.3"	"186.7"	"170.1"	"255.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60884"	"DnaJ homolog subfamily A member 2 OS=Homo sapiens OX=9606 GN=DNAJA2 PE=1 SV=1"	"6"	"2"	"4"	"2"	"412"	"45.7"	"6.48"	"754.48"	"6.72"	"2"	"2"	"stress response;other biological processes"	"other membranes;cytosol;other cell component"	"other molecular function"	"Pf00226, Pf00684, Pf01556"	"10294"	"ENSG00000069345"	"DNAJA2"	"B2R7L7; hsa:10294; O14711; O60884"	"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand"	""	"1"	"0"	"95.0"	"89.8"	"433.3"	"110.2"	"82.8"	"69.9"	"464.2"	"39.3"	"56.7"	"80.0"	"50.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46976"	"Glycogenin-1 OS=Homo sapiens OX=9606 GN=GYG1 PE=1 SV=4"	"6"	"2"	"4"	"2"	"350"	"39.4"	"5.53"	"866.88"	"6.72"	"2"	"2"	"other metabolic processes"	"non-structural extracellular;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01501"	"2992"	"ENSG00000163754"	"GYG1"	"D3DNH0; D3DNH1; D3DNH2; hsa:2992; P46976; Q6FHZ1; Q9UNV0"	"Neutrophil degranulation; Glycogen synthesis; Glycogen breakdown (glycogenolysis); Myoclonic epilepsy of Lafora; Glycogen storage disease type II (GAA); Glycogen storage disease type XV (GYG1); Glycogen storage disease type 0 (muscle GYS1)"	"Insulin signaling; Glycogen synthesis and degradation; Disorders of galactose metabolism"	"10"	"0"	"202.9"	"217.0"	"553.5"	"223.3"	"200.4"	"178.0"	"691.3"	"164.4"	"189.1"	"151.3"	"160.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q969S3"	"Zinc finger protein 622 OS=Homo sapiens OX=9606 GN=ZNF622 PE=1 SV=1"	"6"	"3"	"5"	"3"	"477"	"54.2"	"6.15"	"589.70"	"6.71"	"2"	"3"	"signal transduction;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf12171, Pf12756"	"90441"	"ENSG00000173545"	"ZNF622"	"hsa:90441; Q969S3"	""	""	"0"	"0"	"41.1"	"49.0"	"123.9"	"46.4"	"35.5"	"31.0"	"132.5"	"11.0"	"19.5"	"14.4"	"17.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01970"	"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 OS=Homo sapiens OX=9606 GN=PLCB3 PE=1 SV=2"	"3"	"2"	"4"	"2"	"1234"	"138.7"	"5.90"	"825.38"	"6.70"	"2"	"2"	"other metabolic processes;transport;signal transduction;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00168, Pf00387, Pf00388, Pf08703, Pf09279, Pf17787"	"5331"	"ENSG00000149782"	"PLCB3"	"A5PKZ6; G5E960; hsa:5331; Q01970; Q8N1A4"	"G alpha (q) signalling events; Ca2+ pathway; G beta:gamma signalling through PLC beta; Presynaptic function of Kainate receptors; Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion; Synthesis of IP3 and IP4 in the cytosol; PLC beta mediated events; Acetylcholine regulates insulin secretion"	"Alzheimer's disease and miRNA effects; S1P receptor signal transduction; Myometrial relaxation and contraction pathways; G protein signaling pathways; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; GPR40 pathway; MAPK cascade; Wnt signaling; Non-genomic actions of 1,25 dihydroxyvitamin D3; Resistin as a regulator of inflammation; Hippo signaling regulation pathways; PKC-gamma calcium signaling pathway in ataxia; Kisspeptin/kisspeptin receptor system in the ovary; GPR143 in melanocytes and retinal pigment epithelium cells; Neuroinflammation and glutamatergic signaling; Alzheimer's disease; Calcium regulation in cardiac cells"	"26"	"0"	"13.6"	"17.3"	"63.5"	"17.0"	"11.9"	"11.7"	"38.2"	"3.8"	"3.8"	"10.0"	"7.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UDY4"	"DnaJ homolog subfamily B member 4 OS=Homo sapiens OX=9606 GN=DNAJB4 PE=1 SV=1"	"9"	"2"	"4"	"1"	"337"	"37.8"	"8.50"	"659.78"	"6.67"	"2"	"2"	"stress response;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus"	"other molecular function"	"Pf00226, Pf01556"	"11080"	"ENSG00000162616"	"DNAJB4"	"B2R824; hsa:11080; Q13431; Q9UDY4"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"12.9"	"10.7"	"44.7"	"5.6"	"10.2"	"7.7"	"35.2"	"0.0"	"7.1"	"4.6"	"6.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00330"	"Pyruvate dehydrogenase protein X component, mitochondrial OS=Homo sapiens OX=9606 GN=PDHX PE=1 SV=3"	"9"	"5"	"7"	"5"	"501"	"54.1"	"8.66"	"1537.67"	"6.65"	"5"	"2"	"other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf00198, Pf00364, Pf02817"	"8050"	"ENSG00000110435"	"PDHX"	"B4DW62; D3DR11; E9PB14; E9PBP7; hsa:8050; O00330; O60221; Q96FV8; Q99783"	"Glyoxylate metabolism and glycine degradation; Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid"	"Amino acid metabolism"	"5"	"0"	"434.3"	"447.7"	"1251.2"	"465.8"	"424.9"	"331.6"	"1092.0"	"165.2"	"251.0"	"214.6"	"270.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30040"	"Endoplasmic reticulum resident protein 29 OS=Homo sapiens OX=9606 GN=ERP29 PE=1 SV=4"	"8"	"2"	"4"	"2"	"261"	"29.0"	"7.31"	"681.77"	"6.65"	"2"	"2"	"transport;other biological processes"	"ER/Golgi;other cell component"	"other molecular function"	"Pf07749, Pf07912"	"10961"	"ENSG00000089248"	"ERP29"	"C9J183; hsa:10961; P30040; Q3MJC3; Q6FHT4"	""	""	"0"	"0"	"152.8"	"150.6"	"508.9"	"173.0"	"118.3"	"79.4"	"605.1"	"92.0"	"134.7"	"106.3"	"115.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P68431"	"Histone H3.1 OS=Homo sapiens OX=9606 GN=H3C1 PE=1 SV=2"	"12"	"2"	"4"	"2"	"136"	"15.4"	"11.12"	"513.65"	"6.63"	"2"	"2"	"cell organization and biogenesis;other metabolic processes"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125"	"8350; 8351; 8352; 8353; 8354; 8355; 8356; 8357; 8358; 8968"	"ENSG00000197153; ENSG00000197409; ENSG00000273983; ENSG00000274750; ENSG00000275379; ENSG00000275714; ENSG00000277775; ENSG00000278828; ENSG00000286522; ENSG00000287080"	"H3C1; H3C10; H3C11; H3C12; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8"	"A0PJT7; A5PLR1; hsa:8350; hsa:8351; hsa:8352; hsa:8353; hsa:8354; hsa:8355; hsa:8356; hsa:8357; hsa:8358; hsa:8968; P02295; P02296; P16106; P68431; Q6ISV8; Q6NWP8; Q6NWP9; Q6NXU4; Q71DJ3; Q93081"	"Transcriptional regulation by small RNAs; Oxidative Stress Induced Senescence; Pre-NOTCH Transcription and Translation; Factors involved in megakaryocyte development and platelet production; Condensation of Prophase Chromosomes; Estrogen-dependent gene expression; Amyloid fiber formation; HCMV Late Events; RUNX1 regulates transcription of genes involved in differentiation of HSCs; HCMV Early Events; B-WICH complex positively regulates rRNA expression; Formation of the beta-catenin:TCF transactivating complex; HDACs deacetylate histones; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Senescence-Associated Secretory Phenotype (SASP); RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; HATs acetylate histones; RNA Polymerase I Promoter Escape; Meiotic recombination; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis; Interleukin-7 signaling; RMTs methylate histone arginines; HDMs demethylate histones; PKMTs methylate histone lysines"	"Histone modifications; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma"	"36"	"0"	"281.7"	"415.1"	"1142.2"	"357.4"	"369.4"	"322.5"	"1280.6"	"154.1"	"223.8"	"170.4"	"168.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14254"	"Flotillin-2 OS=Homo sapiens OX=9606 GN=FLOT2 PE=1 SV=2"	"8"	"2"	"4"	"2"	"428"	"47.0"	"5.25"	"835.05"	"6.63"	"2"	"2"	"cell adhesion;transport;other biological processes"	"plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	""	"Pf01145"	"2319"	"ENSG00000132589"	"FLOT2"	"hsa:2319; Q14254"	"RND3 GTPase cycle; RHOC GTPase cycle; RHOA GTPase cycle; RHOB GTPase cycle; RND1 GTPase cycle; Regulation of necroptotic cell death; Synaptic adhesion-like molecules"	"Angiopoietin-like protein 8 regulatory pathway; Insulin signaling"	"10"	"0"	"8.8"	"7.6"	"44.2"	"9.2"	"10.1"	"4.4"	"42.2"	"2.5"	"5.8"	"5.0"	"6.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51149"	"Ras-related protein Rab-7a OS=Homo sapiens OX=9606 GN=RAB7A PE=1 SV=1"	"17"	"3"	"5"	"3"	"207"	"23.5"	"6.70"	"1099.47"	"6.62"	"3"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00071"	"7879"	"ENSG00000075785"	"RAB7A"	"A8K3V6; hsa:7879; P51149; Q9NWJ0; Q9UPB0"	"RAC1 GTPase cycle; RHOG GTPase cycle; Prevention of phagosomal-lysosomal fusion; RAB geranylgeranylation; TBC/RABGAPs; CDC42 GTPase cycle; RHOQ GTPase cycle; RAB GEFs exchange GTP for GDP on RABs; MHC class II antigen presentation; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOD GTPase cycle; RHOJ GTPase cycle; RHOF GTPase cycle; Neutrophil degranulation; Suppression of autophagy; RHOH GTPase cycle"	"Ebola virus infection in host; Autosomal recessive osteopetrosis pathways; Intracellular trafficking proteins involved in CMT neuropathy"	"20"	"0"	"219.1"	"193.6"	"926.9"	"191.6"	"164.1"	"116.0"	"922.6"	"83.8"	"116.8"	"100.4"	"117.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NYB0"	"Telomeric repeat-binding factor 2-interacting protein 1 OS=Homo sapiens OX=9606 GN=TERF2IP PE=1 SV=1"	"9"	"2"	"4"	"2"	"399"	"44.2"	"4.73"	"783.64"	"6.62"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf08914, Pf11626, Pf16589"	"54386"	"ENSG00000166848"	"TERF2IP"	"B4DQN4; hsa:54386; Q4W4Y2; Q8WYZ3; Q9NWR2; Q9NYB0"	"DNA Damage/Telomere Stress Induced Senescence; Meiotic synapsis; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; Packaging Of Telomere Ends; Polymerase switching on the C-strand of the telomere; Removal of the Flap Intermediate from the C-strand; Telomere Extension By Telomerase; Telomere C-strand synthesis initiation"	"Splicing factor NOVA regulated synaptic proteins; SARS-CoV-2 mitochondrial chronic oxidative stress and endothelial dysfunction"	"16"	"0"	"43.2"	"53.3"	"159.9"	"44.7"	"51.7"	"50.2"	"174.4"	"40.8"	"48.9"	"30.8"	"28.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P1F3"	"Costars family protein ABRACL OS=Homo sapiens OX=9606 GN=ABRACL PE=1 SV=1"	"27"	"2"	"4"	"2"	"81"	"9.1"	"6.29"	"767.67"	"6.61"	"2"	"2"	"other biological processes"	""	""	"Pf14705"	"58527"	"ENSG00000146386"	"ABRACL"	"hsa:58527; Q5SZC8; Q9P0A1; Q9P1F3"	""	""	"0"	"0"	"56.4"	"64.2"	"805.3"	"69.9"	"62.9"	"30.8"	"1150.6"	"27.2"	"3.6"	"23.3"	"15.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15102"	"Platelet-activating factor acetylhydrolase IB subunit gamma OS=Homo sapiens OX=9606 GN=PAFAH1B3 PE=1 SV=1"	"11"	"2"	"4"	"2"	"231"	"25.7"	"6.84"	"595.84"	"6.61"	"2"	"2"	"other metabolic processes;developmental processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf13472"	"5050"	"ENSG00000079462"	"PAFAH1B3"	"hsa:5050; Q15102; Q53X88"	"COPI-independent Golgi-to-ER retrograde traffic"	""	"1"	"0"	"85.0"	"110.9"	"395.7"	"107.3"	"82.6"	"54.2"	"425.1"	"69.7"	"72.4"	"50.0"	"46.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H444"	"Charged multivesicular body protein 4b OS=Homo sapiens OX=9606 GN=CHMP4B PE=1 SV=1"	"19"	"4"	"6"	"4"	"224"	"24.9"	"4.82"	"1558.27"	"6.56"	"4"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf03357"	"128866"	"ENSG00000101421"	"CHMP4B"	"E1P5N4; hsa:128866; Q53ZD6; Q9H444"	"Sealing of the nuclear envelope (NE) by ESCRT-III; Budding and maturation of HIV virion; Endosomal Sorting Complex Required For Transport (ESCRT); HCMV Late Events; Late endosomal microautophagy; Macroautophagy; Pyroptosis; Translation of Replicase and Assembly of the Replication Transcription Complex; Translation of Replicase and Assembly of the Replication Transcription Complex"	""	"9"	"0"	"415.5"	"471.1"	"1557.0"	"503.4"	"454.8"	"408.5"	"2257.7"	"276.7"	"478.1"	"331.7"	"346.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z2W4"	"Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3"	"1"	"1"	"4"	"1"	"902"	"101.4"	"8.40"	"597.32"	"6.55"	"1"	"1"	"stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00644, Pf02825, Pf18606, Pf18633"	"56829"	"ENSG00000105939"	"ZC3HAV1"	"A4D1R2; A4D1S4; hsa:56829; Q7Z2W4; Q8IW57; Q8TAJ3; Q96N79; Q9H8R9; Q9P0Y7"	"Signaling by BRAF and RAF1 fusions"	""	"1"	"0"	"31.7"	"35.6"	"95.4"	"25.8"	"31.1"	"27.8"	"120.1"	"34.3"	"50.6"	"40.9"	"47.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96AC1"	"Fermitin family homolog 2 OS=Homo sapiens OX=9606 GN=FERMT2 PE=1 SV=1"	"7"	"3"	"6"	"3"	"680"	"77.8"	"6.70"	"1171.23"	"6.52"	"3"	"2"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00169, Pf00373, Pf18124"	"10979"	"ENSG00000073712"	"FERMT2"	"B5TJY2; hsa:10979; Q14840; Q86TY7; Q96AC1"	"RAC1 GTPase cycle; RAC3 GTPase cycle; Cell-extracellular matrix interactions"	""	"3"	"0"	"26.9"	"25.6"	"126.8"	"29.1"	"27.2"	"21.6"	"107.1"	"21.1"	"35.6"	"68.7"	"160.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NZQ3"	"NCK-interacting protein with SH3 domain OS=Homo sapiens OX=9606 GN=NCKIPSD PE=1 SV=1"	"2"	"1"	"4"	"1"	"722"	"78.9"	"6.38"	"829.77"	"6.51"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"cytosol;cytoskeleton;nucleus"	"cytoskeletal activity;other molecular function"	"Pf00018, Pf09431"	"51517"	"ENSG00000213672"	"NCKIPSD"	"B4DFL5; hsa:51517; Q6GU34; Q6SPF3; Q8TC10; Q9NZQ3; Q9UGM8"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs"	""	"3"	"0"	"9.0"	"10.6"	"41.8"	"10.3"	"9.3"	"7.6"	"40.5"	"7.6"	"8.0"	"9.8"	"7.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P54578"	"Ubiquitin carboxyl-terminal hydrolase 14 OS=Homo sapiens OX=9606 GN=USP14 PE=1 SV=3"	"6"	"2"	"4"	"2"	"494"	"56.0"	"5.30"	"851.89"	"6.51"	"2"	"2"	"cell-cell signaling;protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00443"	"9097"	"ENSG00000101557"	"USP14"	"B7Z4N8; hsa:9097; J3QRZ5; P54578; Q53XY5"	"Ub-specific processing proteases; Regulation of NF-kappa B signaling"	""	"2"	"0"	"54.5"	"60.6"	"264.3"	"61.7"	"48.1"	"36.8"	"273.4"	"32.5"	"50.8"	"38.6"	"39.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P2R7"	"Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLA2 PE=1 SV=3"	"5"	"2"	"4"	"2"	"463"	"50.3"	"7.42"	"791.22"	"6.51"	"2"	"2"	"other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf00549, Pf08442"	"8803"	"ENSG00000136143"	"SUCLA2"	"B2RDE7; hsa:8803; O95194; Q5T9Q4; Q5T9Q6; Q9NV21; Q9NVP7; Q9P2R7"	"Citric acid cycle (TCA cycle)"	""	"1"	"0"	"70.1"	"71.9"	"327.8"	"80.1"	"69.4"	"45.3"	"331.1"	"22.9"	"38.3"	"34.8"	"27.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60502"	"Protein O-GlcNAcase OS=Homo sapiens OX=9606 GN=OGA PE=1 SV=2"	"1"	"1"	"4"	"1"	"916"	"102.8"	"4.91"	"714.52"	"6.48"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf07555"	"10724"	"ENSG00000198408"	"OGA"	"B7WPB9; D3DR79; E9PGF9; hsa:10724; O60502; O75166; Q86WV0; Q8IV98; Q9BVA5; Q9HAR0"	""	""	"0"	"0"	"29.8"	"40.0"	"195.9"	"36.8"	"39.5"	"33.3"	"200.3"	"21.8"	"31.4"	"31.7"	"19.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NP92"	"39S ribosomal protein S30, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS30 PE=1 SV=2"	"7"	"2"	"4"	"2"	"439"	"50.3"	"7.97"	"690.84"	"6.47"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf07147"	"10884"	"ENSG00000112996"	"MRPS30"	"hsa:10884; Q96I91; Q96Q19; Q9H0P8; Q9NP92; Q9NSF9; Q9NZ76"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"17.7"	"16.5"	"47.1"	"15.4"	"24.5"	"13.1"	"58.4"	"7.6"	"18.3"	"21.6"	"13.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96GQ7"	"Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2"	"4"	"3"	"5"	"3"	"796"	"89.8"	"9.28"	"1053.98"	"6.45"	"3"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271"	"55661"	""	"DDX27"	"A0AVB6; B7ZLY1; hsa:55661; Q5VXM7; Q8WYG4; Q969N7; Q96F57; Q96GQ7; Q96L97; Q9BWY9; Q9BXF0; Q9H990; Q9NWU3; Q9P0C2; Q9UGD6"	""	""	"0"	"0"	"9.0"	"10.9"	"42.3"	"16.4"	"8.0"	"7.0"	"34.0"	"6.5"	"6.9"	"3.9"	"3.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96N67"	"Dedicator of cytokinesis protein 7 OS=Homo sapiens OX=9606 GN=DOCK7 PE=1 SV=4"	"1"	"3"	"5"	"3"	"2140"	"242.4"	"6.80"	"1004.72"	"6.45"	"3"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"other cell component"	"enzyme regulator activity;other molecular function"	"Pf06920, Pf11878, Pf14429, Pf20421, Pf20422"	"85440"	"ENSG00000116641"	"DOCK7"	"hsa:85440; Q00M63; Q2PPY7; Q45RE8; Q45RE9; Q5T1B9; Q5T1C0; Q6ZV32; Q8TB82; Q96N67; Q96NG6; Q96NI0; Q9C092"	"CDC42 GTPase cycle; RAC1 GTPase cycle; Factors involved in megakaryocyte development and platelet production; MET activates RAP1 and RAC1"	""	"4"	"0"	"126.6"	"136.6"	"335.4"	"108.9"	"99.7"	"96.7"	"314.6"	"44.2"	"79.1"	"82.6"	"86.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TAF3"	"WD repeat-containing protein 48 OS=Homo sapiens OX=9606 GN=WDR48 PE=1 SV=1"	"4"	"1"	"1"	"1"	"677"	"76.2"	"7.03"	""	"6.44"	""	"1"	"DNA metabolism;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00400, Pf11816"	"57599"	"ENSG00000114742"	"WDR48"	"B4DM86; B4DQI2; B4DY84; hsa:57599; Q63HJ2; Q658Y1; Q8N3Z1; Q8TAF3; Q9NSK8; Q9P279"	"Ub-specific processing proteases; Fanconi Anemia Pathway; Signaling by cytosolic PDGFRA and PDGFRB fusion proteins; Recognition of DNA damage by PCNA-containing replication complex"	"DNA repair pathways, full network"	"5"	"0"	"9.0"	"6.9"	"38.9"	"7.9"	"11.0"	"8.7"	"55.7"	"12.9"	"42.5"	"55.6"	"58.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P47755"	"F-actin-capping protein subunit alpha-2 OS=Homo sapiens OX=9606 GN=CAPZA2 PE=1 SV=3"	"13"	"2"	"4"	"2"	"286"	"32.9"	"5.85"	"815.73"	"6.44"	"2"	"2"	"cell organization and biogenesis"	"non-structural extracellular;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf01267"	"830"	"ENSG00000198898"	"CAPZA2"	"B4DG50; hsa:830; P47755"	"MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Sensory processing of sound by inner hair cells of the cochlea; Factors involved in megakaryocyte development and platelet production; Advanced glycosylation endproduct receptor signaling"	""	"7"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13554"	"Calcium/calmodulin-dependent protein kinase type II subunit beta OS=Homo sapiens OX=9606 GN=CAMK2B PE=1 SV=3"	"5"	"2"	"4"	"2"	"666"	"72.6"	"7.27"	"760.80"	"6.43"	"2"	"2"	"protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;kinase activity;other molecular function"	"Pf00069, Pf08332"	"816"	"ENSG00000058404"	"CAMK2B"	"A4D2K0; A4D2K1; A4D2K2; A4D2K3; A4D2K4; A4D2K5; A4D2K6; hsa:816; O95437; O95438; O95599; Q13554; Q9UGH7; Q9UGH8; Q9UGH9; Q9UNX0; Q9UNX7; Q9UP00; Q9Y5N4; Q9Y6F4"	"Signaling by BRAF and RAF1 fusions; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; Assembly and cell surface presentation of NMDA receptors; Ion homeostasis; Ion transport by P-type ATPases; Interferon gamma signaling; RAF activation; Ras activation upon Ca2+ influx through NMDA receptor; Regulation of MECP2 expression and activity; Unblocking of NMDA receptors, glutamate binding and activation; Negative regulation of NMDA receptor-mediated neuronal transmission; Long-term potentiation; Trafficking of AMPA receptors; Phase 0 - rapid depolarisation; HSF1-dependent transactivation; CaMK IV-mediated phosphorylation of CREB; CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde"	"Primary focal segmental glomerulosclerosis (FSGS); Myometrial relaxation and contraction pathways; Serotonin and anxiety; NO/cGMP/PKG mediated neuroprotection; Wnt signaling; Non-genomic actions of 1,25 dihydroxyvitamin D3; Synaptic signaling pathways associated with autism spectrum disorder; Fragile X syndrome; Disruption of postsynaptic signaling by CNV; Neuroinflammation and glutamatergic signaling; GDNF signaling; Hippocampal synaptogenesis and neurogenesis; Calcium regulation in cardiac cells; ErbB signaling pathway"	"35"	"0"	"44.4"	"57.0"	"222.3"	"50.0"	"42.0"	"37.3"	"252.1"	"19.7"	"37.1"	"30.5"	"33.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UNN5"	"FAS-associated factor 1 OS=Homo sapiens OX=9606 GN=FAF1 PE=1 SV=2"	"4"	"2"	"4"	"2"	"650"	"73.9"	"4.88"	"686.69"	"6.43"	"2"	"2"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00789, Pf14555"	"11124"	"ENSG00000185104"	"FAF1"	"hsa:11124; Q549F0; Q9UF34; Q9UNN5; Q9UNT3; Q9Y2Z3"	""	"Retinoblastoma gene in cancer; Fas ligand pathway and stress induction of heat shock proteins; VEGFA-VEGFR2 signaling"	"3"	"0"	"58.0"	"64.6"	"259.5"	"76.2"	"76.0"	"54.0"	"342.3"	"47.9"	"78.0"	"51.1"	"37.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35613"	"Basigin OS=Homo sapiens OX=9606 GN=BSG PE=1 SV=2"	"6"	"2"	"4"	"2"	"385"	"42.2"	"5.66"	"669.31"	"6.41"	"2"	"2"	"developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf13927"	"682"	"ENSG00000172270"	"BSG"	"A6NJW1; D3YLG5; hsa:682; P35613; Q7Z796; Q8IZL7"	"Degradation of the extracellular matrix; Integrin cell surface interactions; Pyruvate metabolism; Aspirin ADME; Basigin interactions; Proton-coupled monocarboxylate transport; Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT)"	"Matrix metalloproteinases; VEGFA-VEGFR2 signaling; IL-18 signaling pathway"	"10"	"0"	"144.9"	"149.7"	"766.7"	"151.0"	"133.6"	"106.3"	"700.1"	"69.6"	"128.0"	"106.1"	"130.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UHX1"	"Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1"	"4"	"1"	"1"	"1"	"559"	"59.8"	"5.29"	""	"6.38"	""	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"22827"	"ENSG00000179950; ENSG00000274081"	"PUF60"	"A8K8K8; hsa:22827; Q969E7; Q96D94; Q96H63; Q99628; Q9NZA0; Q9UHX1; Q9UJY7"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"33.6"	"41.8"	"124.2"	"41.3"	"37.1"	"32.3"	"168.2"	"22.4"	"43.2"	"41.0"	"55.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12899"	"Tripartite motif-containing protein 26 OS=Homo sapiens OX=9606 GN=TRIM26 PE=1 SV=1"	"5"	"2"	"4"	"2"	"539"	"62.1"	"5.03"	"763.49"	"6.37"	"2"	"2"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00622, Pf00643, Pf13765, Pf15227"	"7726"	"ENSG00000137313; ENSG00000226060; ENSG00000228881; ENSG00000230230; ENSG00000231002; ENSG00000231641; ENSG00000234046; ENSG00000234127"	"TRIM26"	"A6NG96; hsa:7726; Q12899; Q5SRL2"	"Interferon gamma signaling"	""	"1"	"0"	"8.6"	"10.6"	"40.5"	"13.3"	"9.3"	"4.9"	"43.7"	"9.8"	"8.2"	"6.9"	"4.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BWU0"	"Kanadaptin OS=Homo sapiens OX=9606 GN=SLC4A1AP PE=1 SV=1"	"4"	"2"	"3"	"2"	"796"	"88.8"	"5.19"	"297.63"	"6.37"	"1"	"2"	""	"plasma membrane;other membranes;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00498"	"22950"	"ENSG00000163798"	"SLC4A1AP"	"A6NJ39; hsa:22950; Q4KMT1; Q4KMX0; Q7Z5Q9; Q9BWU0; Q9NVN2"	""	""	"0"	"0"	"78.4"	"112.3"	"357.8"	"106.7"	"82.3"	"73.5"	"401.5"	"45.5"	"62.7"	"51.1"	"40.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5H9R7"	"Serine/threonine-protein phosphatase 6 regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PPP6R3 PE=1 SV=2"	"2"	"2"	"4"	"2"	"873"	"97.6"	"4.60"	"815.82"	"6.33"	"2"	"2"	"other biological processes"	"plasma membrane;other membranes;cytosol;nucleus"	"enzyme regulator activity;other molecular function"	"Pf04499"	"55291"	"ENSG00000110075"	"PPP6R3"	"hsa:55291; Q3B7I1; Q3I4Y0; Q3KR35; Q5H9R7; Q68CR3; Q7L4R8; Q8N3B2; Q96MB2; Q9H2K5; Q9H2K6; Q9HCL4; Q9NUY3"	"Telomere Extension By Telomerase; COPII-mediated vesicle transport"	""	"2"	"0"	"151.8"	"165.4"	"632.4"	"130.6"	"112.3"	"88.2"	"621.5"	"54.3"	"71.4"	"63.4"	"65.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75179"	"Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3"	"1"	"3"	"5"	"3"	"2603"	"274.1"	"6.52"	"987.93"	"6.32"	"3"	"2"	"stress response;developmental processes;other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf00013, Pf12796"	"26057"	"ENSG00000132466"	"ANKRD17"	"E7EUV3; G5E964; hsa:26057; O75179; Q6PJ85; Q6PK85; Q6PKA2; Q86XI3; Q8NDR5; Q96I86; Q9H288; Q9H6J9"	""	""	"0"	"0"	"34.6"	"34.8"	"97.7"	"24.5"	"25.3"	"18.4"	"100.3"	"16.7"	"28.2"	"23.6"	"20.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15075"	"Early endosome antigen 1 OS=Homo sapiens OX=9606 GN=EEA1 PE=1 SV=2"	"2"	"2"	"4"	"2"	"1411"	"162.4"	"5.68"	"586.47"	"6.31"	"2"	"2"	"cell-cell signaling;cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01363"	"8411"	"ENSG00000102189"	"EEA1"	"hsa:8411; Q14221; Q15075"	"Toll Like Receptor 9 (TLR9) Cascade"	"VEGFA-VEGFR2 signaling"	"2"	"0"	"12.4"	"12.3"	"80.6"	"10.9"	"16.6"	"6.8"	"65.6"	"7.5"	"12.1"	"13.1"	"14.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2R5"	"28S ribosomal protein S17, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS17 PE=1 SV=1"	"24"	"2"	"3"	"2"	"130"	"14.5"	"9.85"	"562.63"	"6.30"	"1"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity"	"Pf00366"	"51373"	"ENSG00000239789"	"MRPS17"	"hsa:51373; Q86X15; Q9Y2R5"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"94.3"	"90.4"	"293.6"	"106.2"	"96.7"	"66.2"	"309.7"	"48.4"	"85.2"	"72.9"	"82.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13112"	"Chromatin assembly factor 1 subunit B OS=Homo sapiens OX=9606 GN=CHAF1B PE=1 SV=1"	"6"	"2"	"3"	"2"	"559"	"61.5"	"7.50"	"357.90"	"6.29"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf00400, Pf15512"	"8208"	"ENSG00000159259"	"CHAF1B"	"hsa:8208; Q13112; Q99548"	""	""	"0"	"0"	"37.3"	"47.6"	"117.4"	"40.0"	"46.5"	"27.6"	"147.4"	"32.8"	"45.2"	"36.0"	"49.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75306"	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2"	"5"	"2"	"4"	"2"	"463"	"52.5"	"7.55"	"578.54"	"6.27"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"other membranes;mitochondrion;nucleus"	"transporter activity;other molecular function"	"Pf00346"	"4720"	"ENSG00000158864"	"NDUFS2"	"D3DVG7; hsa:4720; J3KPM7; O75306; Q5VTW0; Q969P3; Q9UEV3"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"5"	"0"	"149.9"	"167.9"	"618.6"	"163.7"	"145.2"	"112.2"	"623.7"	"81.3"	"125.3"	"83.3"	"67.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UK45"	"U6 snRNA-associated Sm-like protein LSm7 OS=Homo sapiens OX=9606 GN=LSM7 PE=1 SV=1"	"40"	"3"	"4"	"3"	"103"	"11.6"	"5.27"	"579.83"	"6.27"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01423"	"51690"	"ENSG00000130332"	"LSM7"	"hsa:51690; Q9UK45"	"mRNA Splicing - Major Pathway; mRNA decay by 5' to 3' exoribonuclease"	"mRNA processing"	"3"	"0"	"302.4"	"402.4"	"1784.8"	"379.8"	"291.3"	"241.6"	"2025.4"	"183.8"	"304.8"	"256.4"	"276.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01469"	"Fatty acid-binding protein 5 OS=Homo sapiens OX=9606 GN=FABP5 PE=1 SV=3"	"24"	"3"	"4"	"3"	"135"	"15.2"	"7.01"	"682.60"	"6.25"	"2"	"2"	"other metabolic processes;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf00061"	"2171"	"ENSG00000164687"	"FABP5"	"B2R4K0; hsa:2171; Q01469"	"Neutrophil degranulation; Triglyceride catabolism; Signaling by Retinoic Acid"	"PPAR signaling pathway; Fatty acid transporters"	"5"	"0"	"301.8"	"266.9"	"1274.1"	"186.6"	"138.3"	"110.5"	"1906.3"	"121.3"	"91.9"	"101.7"	"117.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96GC5"	"39S ribosomal protein L48, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL48 PE=1 SV=2"	"5"	"1"	"4"	"1"	"212"	"23.9"	"8.98"	"776.23"	"6.25"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	""	"Pf00338"	"51642"	"ENSG00000175581"	"MRPL48"	"B4DN34; hsa:51642; Q49AK7; Q4U2Q4; Q96GC5; Q9P091; Q9Y5J0"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"148.4"	"176.3"	"574.1"	"167.3"	"153.4"	"121.3"	"644.2"	"105.4"	"132.4"	"125.5"	"138.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61962"	"DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1"	"6"	"2"	"4"	"2"	"342"	"38.9"	"5.52"	"545.54"	"6.25"	"2"	"2"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00400"	"10238"	"ENSG00000136485"	"DCAF7"	"B4E039; D3DU14; hsa:10238; O15491; P61962; Q9DAE4"	"Neddylation; Association of TriC/CCT with target proteins during biosynthesis"	"Ciliary landscape; DYRK1A involvement regarding cell proliferation in brain development"	"4"	"0"	"102.0"	"117.4"	"343.0"	"138.7"	"146.9"	"131.2"	"441.4"	"92.5"	"158.3"	"116.3"	"110.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BT78"	"COP9 signalosome complex subunit 4 OS=Homo sapiens OX=9606 GN=COPS4 PE=1 SV=1"	"7"	"2"	"4"	"2"	"406"	"46.2"	"5.83"	"655.47"	"6.25"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf01399, Pf18420"	"51138"	"ENSG00000138663"	"COPS4"	"B3KN88; B3KST5; hsa:51138; Q561W7; Q9BT78; Q9NW31; Q9Y677"	"Neddylation; Formation of TC-NER Pre-Incision Complex; DNA Damage Recognition in GG-NER; Cargo recognition for clathrin-mediated endocytosis; RHOBTB1 GTPase cycle"	"Ciliary landscape"	"6"	"0"	"36.0"	"33.1"	"119.2"	"27.4"	"28.3"	"24.9"	"103.5"	"10.7"	"25.7"	"22.0"	"17.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15555"	"Microtubule-associated protein RP/EB family member 2 OS=Homo sapiens OX=9606 GN=MAPRE2 PE=1 SV=1"	"6"	"2"	"4"	"1"	"327"	"37.0"	"5.57"	"673.41"	"6.25"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf03271"	"10982"	"ENSG00000166974"	"MAPRE2"	"B2RE21; B3KR39; B4DJV4; B7Z2L3; E9PHR3; F5H1V8; G5E9I6; hsa:10982; Q15555; Q9UQ33"	""	"Ciliary landscape"	"1"	"0"	"19.9"	"21.6"	"107.7"	"30.8"	"14.4"	"11.3"	"84.3"	"7.2"	"10.4"	"7.4"	"10.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5VYK3"	"Proteasome adapter and scaffold protein ECM29 OS=Homo sapiens OX=9606 GN=ECPAS PE=1 SV=2"	"1"	"2"	"4"	"2"	"1845"	"204.2"	"7.12"	"690.53"	"6.24"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response"	"cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf13001"	""	"ENSG00000136813"	"ECPAS"	"O15074; Q5VYK3; Q8WU82"	""	""	"0"	"0"	"17.6"	"20.1"	"71.5"	"19.9"	"20.1"	"16.1"	"58.8"	"6.8"	"14.3"	"6.8"	"8.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13098"	"COP9 signalosome complex subunit 1 OS=Homo sapiens OX=9606 GN=GPS1 PE=1 SV=4"	"7"	"2"	"4"	"2"	"491"	"55.5"	"6.74"	"773.31"	"6.22"	"2"	"2"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf01399, Pf10602"	"2873"	"ENSG00000169727"	"GPS1"	"hsa:2873; Q13098; Q8NA10; Q9BWL1"	"Cargo recognition for clathrin-mediated endocytosis; Neddylation; Formation of TC-NER Pre-Incision Complex; RHOBTB1 GTPase cycle; DNA Damage Recognition in GG-NER"	""	"5"	"0"	"24.4"	"31.8"	"66.0"	"21.9"	"20.8"	"17.9"	"69.1"	"11.9"	"16.7"	"17.5"	"16.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5JSZ5"	"Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2"	"1"	"2"	"4"	"1"	"2229"	"242.8"	"8.34"	"574.72"	"6.21"	"2"	"2"	"other biological processes"	""	""	"Pf07001"	"84726"	"ENSG00000288701"	"PRRC2B"	"hsa:84726; O60270; Q5JSZ5; Q5JSZ7; Q66VZ2; Q68CR0; Q96EI9; Q9H683"	""	""	"0"	"0"	"24.6"	"22.1"	"61.9"	"21.6"	"23.1"	"20.2"	"79.5"	"18.5"	"20.0"	"22.9"	"21.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06280"	"Alpha-galactosidase A OS=Homo sapiens OX=9606 GN=GLA PE=1 SV=1"	"5"	"2"	"4"	"2"	"429"	"48.7"	"5.60"	"668.14"	"6.17"	"2"	"2"	"other metabolic processes;other biological processes"	"non-structural extracellular;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf16499, Pf17450"	"2717"	"ENSG00000102393"	"GLA"	"hsa:2717; P06280; Q6LER7"	"Glycosphingolipid metabolism; Neutrophil degranulation"	"Degradation pathway of sphingolipids, including diseases; Ciliary landscape"	"4"	"0"	"63.3"	"73.7"	"282.5"	"62.1"	"66.0"	"44.9"	"318.9"	"38.5"	"52.8"	"39.5"	"34.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3B4"	"Splicing factor 3B subunit 6 OS=Homo sapiens OX=9606 GN=SF3B6 PE=1 SV=1"	"18"	"2"	"4"	"2"	"125"	"14.6"	"9.38"	"619.44"	"6.17"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076"	"51639"	"ENSG00000115128"	"SF3B6"	"hsa:51639; Q53TM1; Q9Y3B4"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	""	"2"	"0"	"79.0"	"91.7"	"352.9"	"71.7"	"66.7"	"58.9"	"421.5"	"44.1"	"67.5"	"58.1"	"59.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UNE7"	"E3 ubiquitin-protein ligase CHIP OS=Homo sapiens OX=9606 GN=STUB1 PE=1 SV=2"	"13"	"3"	"5"	"3"	"303"	"34.8"	"5.87"	"962.50"	"6.14"	"3"	"2"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf04564, Pf12895, Pf18391"	"10273"	"ENSG00000103266"	"STUB1"	"A2IDB9; hsa:10273; O60526; Q969U2; Q9HBT1; Q9UNE7"	"Antigen processing: Ubiquitination & Proteasome degradation; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Regulation of TNFR1 signaling; Regulation of necroptotic cell death; Downregulation of ERBB2 signaling; Downregulation of TGF-beta receptor signaling"	"Androgen receptor signaling pathway; Parkin-ubiquitin proteasomal system pathway"	"10"	"0"	"50.9"	"56.4"	"245.7"	"61.7"	"61.3"	"34.6"	"397.3"	"57.8"	"86.7"	"70.2"	"75.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75531"	"Barrier-to-autointegration factor OS=Homo sapiens OX=9606 GN=BANF1 PE=1 SV=1"	"15"	"2"	"5"	"2"	"89"	"10.1"	"6.09"	"1123.54"	"6.14"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02961"	"8815"	"ENSG00000175334"	"BANF1"	"hsa:8815; O60558; O75531; Q6FGG7"	"Vpr-mediated nuclear import of PICs; 2-LTR circle formation; Integration of viral DNA into host genomic DNA; Autointegration results in viral DNA circles; APOBEC3G mediated resistance to HIV-1 infection; Nuclear Envelope Breakdown; Initiation of Nuclear Envelope (NE) Reformation"	"Envelope proteins and their potential roles in EDMD physiopathology; Familial partial lipodystrophy; Progeria-associated lipodystrophy"	"11"	"0"	"88.7"	"106.0"	"659.9"	"116.0"	"105.4"	"86.9"	"1026.9"	"110.3"	"142.8"	"107.6"	"95.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P00441"	"Superoxide dismutase [Cu-Zn] OS=Homo sapiens OX=9606 GN=SOD1 PE=1 SV=2"	"16"	"2"	"4"	"2"	"154"	"15.9"	"6.13"	"670.58"	"6.13"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"non-structural extracellular;cytosol;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00080"	"6647"	"ENSG00000142168"	"SOD1"	"A6NHJ0; D3DSE4; hsa:6647; P00441; Q16669; Q16711; Q16838; Q16839; Q16840; Q6NR85"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Platelet degranulation ; Detoxification of Reactive Oxygen Species"	"Selenium micronutrient network; Vitamin B12 metabolism; Folate metabolism; AGE/RAGE pathway; Dopamine metabolism; Amyotrophic lateral sclerosis (ALS); Trans-sulfuration, one-carbon metabolism and related pathways; Copper homeostasis; Physico-chemical features and toxicity-associated pathways; Oxidative stress response; Extracellular vesicles in the crosstalk of cardiac cells; Arsenic metabolism and reactive oxygen species generation"	"15"	"0"	"95.8"	"77.8"	"335.8"	"91.4"	"74.5"	"50.3"	"387.3"	"64.6"	"74.6"	"51.4"	"52.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49821"	"NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV1 PE=1 SV=4"	"6"	"2"	"4"	"2"	"464"	"50.8"	"8.21"	"749.72"	"6.10"	"2"	"2"	"other metabolic processes;transport"	"other membranes;cytosol;mitochondrion"	"transporter activity;other molecular function"	"Pf01512, Pf10531, Pf10589"	"4723"	"ENSG00000167792"	"NDUFV1"	"hsa:4723; O60924; O60940; P49821; Q16104; Q6IBR3; Q96BF8; Q96HS7"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"5"	"0"	"45.2"	"50.5"	"203.9"	"36.8"	"51.2"	"23.3"	"250.7"	"18.6"	"22.3"	"29.7"	"26.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UPN3"	"Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4"	"0"	"3"	"4"	"3"	"7388"	"837.8"	"5.39"	"699.02"	"6.10"	"2"	"2"	"cell-cell signaling;cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00435, Pf00681, Pf02187, Pf13499, Pf17902, Pf18373"	"23499"	"ENSG00000127603"	"MACF1"	"B1ALC5; E9PJT0; hsa:23499; O75053; Q5VW20; Q8WXY1; Q8WXY2; Q96PK2; Q9H540; Q9UKP0; Q9ULG9; Q9UPN3"	""	"Mesodermal commitment pathway; Mesodermal commitment pathway"	"2"	"0"	"19.9"	"23.4"	"102.5"	"16.7"	"11.5"	"9.6"	"110.7"	"5.6"	"6.1"	"6.5"	"6.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UJY5"	"ADP-ribosylation factor-binding protein GGA1 OS=Homo sapiens OX=9606 GN=GGA1 PE=1 SV=1"	"5"	"1"	"1"	"1"	"639"	"70.3"	"5.29"	""	"6.08"	""	"1"	"protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00790, Pf02883, Pf03127, Pf18308"	"26088"	"ENSG00000100083"	"GGA1"	"A8K3D3; B0QYR7; hsa:26088; Q5R3N1; Q5TG07; Q6IC75; Q86YA9; Q8NCS6; Q9BW94; Q9UG00; Q9UGW0; Q9UGW1; Q9UJY5"	"Amyloid fiber formation; TBC/RABGAPs"	""	"2"	"0"	"12.6"	"26.3"	"78.0"	"27.1"	"26.0"	"12.4"	"77.4"	"5.9"	"15.0"	"7.5"	"6.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P1K2"	"Polyamine-modulated factor 1 OS=Homo sapiens OX=9606 GN=PMF1 PE=1 SV=2"	"11"	"2"	"3"	"2"	"205"	"23.3"	"5.49"	"339.26"	"6.08"	"1"	"2"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf03980"	"100527963; 11243"	"ENSG00000160783"	"PMF1"	"A8K0C5; hsa:100527963; hsa:11243; Q5TCJ8; Q5TCJ9; Q5TCK0; Q5TCK1; Q5TCK3; Q69YZ9; Q6P1K2; Q6PHR4; Q6ZVE6; Q86VJ6; Q8N4T6; Q9UBQ3"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	""	"6"	"0"	"72.7"	"76.3"	"291.8"	"90.3"	"83.7"	"63.6"	"379.0"	"74.0"	"234.4"	"254.1"	"339.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82912"	"28S ribosomal protein S11, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS11 PE=1 SV=2"	"13"	"2"	"4"	"2"	"194"	"20.6"	"10.81"	"604.91"	"6.07"	"2"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00411"	"64963"	"ENSG00000181991"	"MRPS11"	"B2RD52; hsa:64963; P82912; Q969D7; Q96GI3; Q9BYC3"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"32.3"	"28.2"	"83.3"	"39.1"	"35.5"	"29.1"	"98.4"	"18.1"	"27.9"	"30.7"	"24.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UHV9"	"Prefoldin subunit 2 OS=Homo sapiens OX=9606 GN=PFDN2 PE=1 SV=1"	"15"	"2"	"4"	"2"	"154"	"16.6"	"6.58"	"576.47"	"6.06"	"2"	"2"	"other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01920"	"5202"	"ENSG00000143256"	"PFDN2"	"hsa:5202; Q9P0P7; Q9UHV9; Q9UN05"	"Prefoldin mediated transfer of substrate  to CCT/TriC"	"Cellular proteostasis"	"2"	"0"	"117.8"	"112.7"	"613.6"	"141.2"	"123.7"	"89.7"	"793.0"	"56.2"	"89.3"	"82.9"	"63.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4K4"	"Mitogen-activated protein kinase kinase kinase kinase 5 OS=Homo sapiens OX=9606 GN=MAP4K5 PE=1 SV=2"	"2"	"1"	"2"	"1"	"846"	"95.0"	"7.83"	"475.61"	"6.03"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction"	"plasma membrane;other membranes;cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00780"	"11183"	"ENSG00000012983"	"MAP4K5"	"A0A0A0MQR1; hsa:11183; Q8IYF6; Q9Y4K4"	""	"Angiopoietin-like protein 8 regulatory pathway; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Insulin signaling"	"3"	"0"	"69.2"	"55.4"	"237.5"	"77.0"	"59.7"	"48.4"	"214.2"	"32.4"	"74.1"	"80.2"	"76.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P20339"	"Ras-related protein Rab-5A OS=Homo sapiens OX=9606 GN=RAB5A PE=1 SV=2"	"12"	"2"	"4"	"1"	"215"	"23.6"	"8.15"	"671.78"	"6.02"	"2"	"2"	"cell-cell signaling;cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00071"	"5868"	"ENSG00000144566"	"RAB5A"	"B4DJA5; hsa:5868; P20339; Q6FI44"	"RAB GEFs exchange GTP for GDP on RABs; RAB geranylgeranylation; Clathrin-mediated endocytosis; Synthesis of PIPs at the plasma membrane; Factors involved in megakaryocyte development and platelet production; Prevention of phagosomal-lysosomal fusion; TBC/RABGAPs"	"Amyotrophic lateral sclerosis (ALS); VEGFA-VEGFR2 signaling; Ebola virus infection in host; Ras signaling; Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells; EGF/EGFR signaling pathway; 16p11.2 distal deletion syndrome"	"14"	"1"	"46.7"	"47.2"	"226.0"	"49.5"	"45.8"	"33.6"	"220.4"	"21.6"	"33.5"	"28.1"	"20.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95248"	"Myotubularin-related protein 5 OS=Homo sapiens OX=9606 GN=SBF1 PE=1 SV=4"	"2"	"2"	"4"	"2"	"1868"	"208.3"	"6.90"	"663.23"	"6.02"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf02141, Pf02893, Pf03456, Pf06602, Pf12335"	"6305"	"ENSG00000100241"	"SBF1"	"A0A024R4Z9; A6PVG9; G5E933; hsa:6305; O60228; O95248; Q5JXD8; Q5PPM2; Q96GR9; Q9UGB8"	"RAB GEFs exchange GTP for GDP on RABs; Synthesis of PIPs at the ER membrane"	""	"2"	"0"	"20.1"	"23.0"	"60.9"	"18.4"	"22.7"	"21.0"	"57.8"	"15.5"	"50.8"	"62.9"	"56.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q06124"	"Tyrosine-protein phosphatase non-receptor type 11 OS=Homo sapiens OX=9606 GN=PTPN11 PE=1 SV=3"	"5"	"2"	"4"	"2"	"593"	"68.0"	"7.30"	"790.36"	"6.01"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00017, Pf00102"	"5781"	"ENSG00000179295"	"PTPN11"	"A8K1D9; hsa:5781; Q06124; Q96HD7"	"PIP3 activates AKT signaling; GPVI-mediated activation cascade; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Platelet sensitization by LDL; CTLA4 inhibitory signaling; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Interleukin-3, Interleukin-5 and GM-CSF signaling; PD-1 signaling; Activation of IRF3, IRF7 mediated by TBK1, IKBKE; Signal regulatory protein family interactions; Constitutive Signaling by Aberrant PI3K in Cancer; RET signaling; PI3K Cascade; Signaling by SCF-KIT; Downstream signal transduction; Tie2 Signaling; Interleukin-6 signaling; Signaling by Leptin; Regulation of IFNG signaling; Regulation of IFNA/IFNB signaling; Signaling by CSF3 (G-CSF); GAB1 signalosome; Signaling by CSF1 (M-CSF) in myeloid cells; PI-3K cascade:FGFR1; FRS-mediated FGFR1 signaling; PI-3K cascade:FGFR2; FRS-mediated FGFR2 signaling; FRS-mediated FGFR3 signaling; PI-3K cascade:FGFR3; FRS-mediated FGFR4 signaling; PI-3K cascade:FGFR4; Activated NTRK2 signals through FRS2 and FRS3; Spry regulation of FGF signaling; MAPK3 (ERK1) activation; MAPK1 (ERK2) activation; Prolactin receptor signaling; Interleukin-20 family signaling; Netrin mediated repulsion signals; Interleukin-37 signaling; PECAM1 interactions; MET activates PTPN11; STAT5 activation downstream of FLT3 ITD mutants; Regulation of RUNX1 Expression and Activity; STAT5 Activation"	"IL-5 signaling pathway; Heart development; IL-1 signaling pathway; Leptin signaling pathway; Prolactin signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; Pilocytic astrocytoma; Androgen receptor network in prostate cancer; B cell receptor signaling pathway; Interleukin-11 signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Alpha 6 beta 4 signaling pathway; IL-3 signaling pathway; Kit receptor signaling pathway; Hepatocyte growth factor receptor signaling; RAC1/PAK1/p38/MMP2 pathway; IL6 signaling pathway; Hepatitis C and hepatocellular carcinoma; VEGFA-VEGFR2 signaling; Embryonic stem cell pluripotency pathways; IL-4 signaling pathway; Ras signaling; EGF/EGFR signaling pathway; Fragile X syndrome; Cancer immunotherapy by CTLA4 blockade; Cancer immunotherapy by PD-1 blockade; Gastrin signaling pathway; Netrin-UNC5B signaling pathway; Insulin signaling; IL-2 signaling pathway; Angiotensin II receptor type 1 pathway; Kallmann syndrome; Orexin receptor pathway; GDNF signaling; Interferon type I signaling pathways; Type II interferon signaling; T-cell receptor signaling pathway"	"90"	"0"	"22.0"	"19.9"	"109.7"	"26.6"	"25.3"	"14.4"	"115.7"	"7.6"	"15.5"	"15.1"	"21.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P16219"	"Short-chain specific acyl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ACADS PE=1 SV=1"	"5"	"2"	"4"	"2"	"412"	"44.3"	"7.99"	"609.14"	"6.01"	"2"	"2"	"other metabolic processes"	"cytoskeleton;mitochondrion;nucleus"	"other molecular function"	"Pf00441, Pf02770, Pf02771"	"35"	"ENSG00000122971"	"ACADS"	"hsa:35; P16219; P78331"	"Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of butanoyl-CoA to acetyl-CoA"	"Fatty acid beta-oxidation; Mitochondrial long chain fatty acid beta-oxidation; IL-18 signaling pathway; Mitochondrial fatty acid oxidation disorders"	"6"	"0"	"25.1"	"20.8"	"49.7"	"25.6"	"70.2"	"77.4"	"97.4"	"63.7"	"25.3"	"234.8"	"22.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5L4"	"Mitochondrial import inner membrane translocase subunit Tim13 OS=Homo sapiens OX=9606 GN=TIMM13 PE=1 SV=1"	"27"	"2"	"4"	"2"	"95"	"10.5"	"8.18"	"808.15"	"6.00"	"2"	"2"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf02953"	"26517"	"ENSG00000099800"	"TIMM13"	"hsa:26517; P62206; Q9UHL8; Q9WTL1; Q9Y5L4"	"Mitochondrial protein import"	""	"1"	"0"	"49.7"	"52.7"	"145.1"	"71.9"	"58.7"	"66.7"	"120.9"	"21.7"	"44.6"	"36.6"	"35.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75380"	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS6 PE=1 SV=1"	"12"	"1"	"2"	"1"	"124"	"13.7"	"8.28"	"823.21"	"6.00"	"1"	"1"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf10276"	"4726"	"ENSG00000145494"	"NDUFS6"	"hsa:4726; O75380"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"5"	"0"	"93.1"	"82.2"	"256.4"	"62.3"	"67.7"	"50.2"	"239.5"	"31.2"	"52.8"	"31.8"	"30.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14696"	"LRP chaperone MESD OS=Homo sapiens OX=9606 GN=MESD PE=1 SV=2"	"10"	"2"	"4"	"2"	"234"	"26.1"	"7.78"	"829.05"	"5.99"	"2"	"2"	"cell-cell signaling;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi"	"signal transduction activity or receptor binding;other molecular function"	"Pf10185"	"23184"	"ENSG00000117899"	"MESD"	"B4DW84; D3DW96; hsa:23184; Q14696; Q969U1"	""	""	"0"	"0"	"188.1"	"253.4"	"921.7"	"267.1"	"264.2"	"207.6"	"1037.2"	"103.3"	"205.3"	"157.4"	"246.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P39656"	"Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4"	"5"	"3"	"5"	"3"	"456"	"50.8"	"6.55"	"852.64"	"5.99"	"3"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity"	"Pf03345"	"1650"	"ENSG00000244038"	"DDOST"	"B2RDQ4; B4DJE3; B4DLI2; hsa:1650; O43244; P39656; Q5VWA5; Q8NI93; Q9BUI2"	"Neutrophil degranulation; SRP-dependent cotranslational protein targeting to membrane; Advanced glycosylation endproduct receptor signaling; Asparagine N-linked glycosylation; Maturation of spike protein"	"AGE/RAGE pathway; N-glycan biosynthesis"	"7"	"0"	"433.9"	"418.2"	"1653.6"	"345.3"	"274.1"	"218.2"	"1671.5"	"141.6"	"214.2"	"158.5"	"138.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BTE3"	"Mini-chromosome maintenance complex-binding protein OS=Homo sapiens OX=9606 GN=MCMBP PE=1 SV=2"	"7"	"2"	"2"	"2"	"642"	"72.9"	"5.87"	"259.80"	"5.98"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf09739"	"79892"	"ENSG00000197771"	"MCMBP"	"B3KSP7; hsa:79892; Q6IA56; Q9BTE3; Q9BVT9; Q9H916"	""	""	"0"	"0"	"49.8"	"44.3"	"107.9"	"37.6"	"33.4"	"36.5"	"134.1"	"30.4"	"47.4"	"30.5"	"26.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52732"	"Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2"	"2"	"2"	"4"	"2"	"1056"	"119.1"	"5.64"	"611.96"	"5.98"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225, Pf13931"	"3832"	"ENSG00000138160"	"KIF11"	"A0AV49; B2RMV3; hsa:3832; P52732; Q15716; Q5VWX0"	"COPI-dependent Golgi-to-ER retrograde traffic; MHC class II antigen presentation; Kinesins"	""	"3"	"0"	"38.7"	"28.3"	"151.6"	"30.7"	"25.1"	"17.8"	"102.2"	"22.2"	"45.8"	"75.6"	"89.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15428"	"Splicing factor 3A subunit 2 OS=Homo sapiens OX=9606 GN=SF3A2 PE=1 SV=2"	"6"	"2"	"4"	"2"	"464"	"49.2"	"9.64"	"619.19"	"5.98"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf12874, Pf16835"	"8175"	"ENSG00000104897"	"SF3A2"	"B2RBU1; D6W605; hsa:8175; O75245; Q15428"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"0"	"59.5"	"61.2"	"212.0"	"63.3"	"71.6"	"53.1"	"202.5"	"39.3"	"43.2"	"45.6"	"35.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43809"	"Cleavage and polyadenylation specificity factor subunit 5 OS=Homo sapiens OX=9606 GN=NUDT21 PE=1 SV=1"	"11"	"3"	"5"	"3"	"227"	"26.2"	"8.82"	"1029.28"	"5.97"	"3"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13869"	"11051"	"ENSG00000167005"	"NUDT21"	"hsa:11051; O43809; Q6IB85; Q6NE84"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"mRNA processing"	"5"	"0"	"381.4"	"416.2"	"1218.4"	"364.6"	"381.0"	"308.5"	"1581.0"	"264.1"	"377.9"	"306.5"	"298.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7L2E3"	"ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1"	"4"	"5"	"7"	"5"	"1194"	"133.9"	"8.78"	"1578.47"	"5.97"	"5"	"2"	"cell organization and biogenesis;developmental processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"22907"	"ENSG00000132153"	"DHX30"	"A8K5F1; hsa:22907; O94965; Q7L2E3; Q7Z753; Q96CH4; Q9NUQ0"	""	""	"0"	"0"	"37.2"	"39.6"	"135.7"	"31.1"	"32.4"	"24.5"	"159.6"	"18.4"	"27.2"	"17.1"	"10.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBD5"	"Origin recognition complex subunit 3 OS=Homo sapiens OX=9606 GN=ORC3 PE=1 SV=1"	"3"	"2"	"4"	"2"	"711"	"82.2"	"7.61"	"634.62"	"5.96"	"2"	"2"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf07034, Pf18137, Pf19675"	"23595"	"ENSG00000135336"	"ORC3"	"A2A2T5; B4E025; hsa:23595; Q13565; Q53GY6; Q5T159; Q6IUY7; Q86TN5; Q9UBD5; Q9UG44; Q9UNT6"	"Orc1 removal from chromatin; Assembly of the ORC complex at the origin of replication; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; E2F-enabled inhibition of pre-replication complex formation; CDC6 association with the ORC:origin complex"	"Cell cycle; G1 to S cell cycle control; DNA replication"	"10"	"0"	"35.2"	"43.0"	"157.4"	"34.9"	"42.5"	"25.2"	"143.1"	"11.7"	"29.7"	"20.3"	"14.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14C86"	"GTPase-activating protein and VPS9 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=GAPVD1 PE=1 SV=2"	"2"	"2"	"4"	"2"	"1478"	"164.9"	"5.22"	"545.67"	"5.96"	"2"	"2"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00616, Pf02204, Pf18151"	"26130"	"ENSG00000165219"	"GAPVD1"	"A8MYK3; B0QZ62; B0QZ63; B0QZ64; hsa:26130; Q14C76; Q14C86; Q2Q1W1; Q8ND92; Q8WU86; Q96CZ4; Q9NXQ1; Q9P207; Q9Y4N0"	"RAB GEFs exchange GTP for GDP on RABs; Clathrin-mediated endocytosis"	""	"2"	"0"	"37.6"	"44.3"	"157.9"	"40.2"	"37.1"	"32.1"	"155.7"	"18.6"	"34.6"	"23.3"	"20.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95168"	"NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 OS=Homo sapiens OX=9606 GN=NDUFB4 PE=1 SV=3"	"18"	"2"	"4"	"2"	"129"	"15.2"	"9.85"	"694.48"	"5.94"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;stress response;transport"	"other membranes;mitochondrion;nucleus"	"transporter activity"	"Pf07225"	"4710"	"ENSG00000065518"	"NDUFB4"	"B2RUY3; B9EJC7; hsa:4710; O95168"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"5"	"0"	"128.9"	"143.7"	"482.9"	"130.7"	"112.8"	"81.0"	"490.6"	"57.6"	"102.9"	"90.2"	"107.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12888"	"TP53-binding protein 1 OS=Homo sapiens OX=9606 GN=TP53BP1 PE=1 SV=2"	"2"	"2"	"3"	"2"	"1972"	"213.4"	"4.70"	"293.39"	"5.92"	"1"	"2"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09038, Pf18428"	"7158"	"ENSG00000067369"	"TP53BP1"	"F8VY86; hsa:7158; Q12888; Q2M1Z7; Q4LE46; Q5FWZ3; Q7Z3U4"	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; SUMOylation of transcription factors; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; Nonhomologous End-Joining (NHEJ)"	"ATM signaling pathway; ATM signaling in development and disease"	"7"	"0"	"92.6"	"93.8"	"287.9"	"128.5"	"133.2"	"115.4"	"364.0"	"76.0"	"103.5"	"83.1"	"67.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q53H12"	"Acylglycerol kinase, mitochondrial OS=Homo sapiens OX=9606 GN=AGK PE=1 SV=2"	"5"	"2"	"4"	"2"	"422"	"47.1"	"8.09"	"643.97"	"5.91"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;cytosol;mitochondrion;other cell component"	"kinase activity;other molecular function"	"Pf00781, Pf19712"	"55750"	"ENSG00000006530; ENSG00000262327"	"AGK"	"hsa:55750; Q53H12; Q75KN1; Q96GC3; Q9NP48"	"Signaling by BRAF and RAF1 fusions; Glycerophospholipid biosynthesis"	""	"2"	"0"	"88.7"	"84.1"	"347.5"	"72.9"	"69.9"	"46.8"	"249.9"	"45.7"	"50.3"	"50.0"	"45.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75122"	"CLIP-associating protein 2 OS=Homo sapiens OX=9606 GN=CLASP2 PE=1 SV=3"	"2"	"2"	"4"	"2"	"1294"	"141.0"	"8.40"	"678.93"	"5.90"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf12348"	"23122"	"ENSG00000163539"	"CLASP2"	"B2RTR1; F5H604; hsa:23122; O75122; Q7L8F6; Q8N6R6; Q9BQT3; Q9BQT4; Q9H7A3; Q9NSZ2"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Role of ABL in ROBO-SLIT signaling"	"7q11.23 copy number variation syndrome"	"8"	"0"	"13.3"	"14.8"	"56.6"	"12.0"	"5.6"	"10.1"	"48.6"	"0.0"	"4.7"	"0.0"	"3.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43314"	"Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 OS=Homo sapiens OX=9606 GN=PPIP5K2 PE=1 SV=3"	"2"	"2"	"3"	"2"	"1243"	"140.3"	"8.22"	"345.48"	"5.90"	"1"	"2"	"other metabolic processes;other biological processes"	"cytosol"	"kinase activity;other molecular function"	"Pf00328, Pf18086"	"23262"	"ENSG00000145725"	"PPIP5K2"	"A1NI53; A6NGS8; hsa:23262; O43314; Q8TB50"	"Synthesis of pyrophosphates in the cytosol"	""	"1"	"0"	"44.5"	"40.6"	"115.5"	"41.0"	"39.2"	"29.3"	"266.9"	"74.5"	"157.4"	"139.0"	"153.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99543"	"DnaJ homolog subfamily C member 2 OS=Homo sapiens OX=9606 GN=DNAJC2 PE=1 SV=4"	"5"	"2"	"4"	"2"	"621"	"72.0"	"8.70"	"642.86"	"5.89"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"translation activity;other molecular function"	"Pf00226, Pf00249, Pf16717"	"27000"	"ENSG00000105821"	"DNAJC2"	"A4VCI0; hsa:27000; Q99543; Q9BVX1"	"Regulation of HSF1-mediated heat shock response"	""	"1"	"0"	"26.0"	"18.1"	"70.8"	"24.9"	"28.8"	"14.1"	"98.2"	"15.3"	"22.7"	"28.8"	"15.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BYD3"	"39S ribosomal protein L4, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL4 PE=1 SV=1"	"7"	"2"	"4"	"1"	"311"	"34.9"	"9.72"	"669.17"	"5.89"	"2"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00573"	"51073"	"ENSG00000105364"	"MRPL4"	"A6NNV7; hsa:51073; Q9BW07; Q9BYD3; Q9H4N2; Q9Y317"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"48.8"	"46.4"	"152.7"	"51.1"	"44.2"	"31.9"	"172.6"	"21.7"	"35.1"	"25.0"	"32.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BXJ9"	"N-alpha-acetyltransferase 15, NatA auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA15 PE=1 SV=1"	"2"	"2"	"4"	"2"	"866"	"101.2"	"7.42"	"722.91"	"5.89"	"2"	"2"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity"	"Pf12569, Pf13181"	"80155"	"ENSG00000164134"	"NAA15"	"D3DNY6; hsa:80155; Q52LG9; Q8IWH4; Q8NEV2; Q9BXJ9; Q9H8P6"	""	""	"0"	"0"	"136.7"	"164.3"	"817.4"	"139.4"	"71.3"	"68.9"	"488.3"	"59.3"	"96.6"	"98.9"	"134.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NTZ6"	"RNA-binding protein 12 OS=Homo sapiens OX=9606 GN=RBM12 PE=1 SV=1"	"4"	"3"	"5"	"3"	"932"	"97.3"	"8.63"	"1247.09"	"5.88"	"3"	"2"	"other biological processes"	"nucleus;other cell component"	""	"Pf00076"	"10137"	"ENSG00000244462"	"RBM12"	"B3KRU2; E1P5R6; hsa:10137; O94865; Q8N3B1; Q9H196; Q9NTZ6"	""	""	"0"	"0"	"122.9"	"131.3"	"519.6"	"128.2"	"109.6"	"98.2"	"560.0"	"76.7"	"103.5"	"87.1"	"82.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15511"	"Actin-related protein 2/3 complex subunit 5 OS=Homo sapiens OX=9606 GN=ARPC5 PE=1 SV=3"	"12"	"2"	"5"	"2"	"151"	"16.3"	"5.67"	"1124.26"	"5.88"	"2"	"1"	"cell organization and biogenesis;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf04699"	"10092"	"ENSG00000162704"	"ARPC5"	"A6NEC4; hsa:10092; O15511; Q6PG42"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Neutrophil degranulation; Clathrin-mediated endocytosis; EPHB-mediated forward signaling"	"Pathogenic Escherichia coli infection; Regulation of actin cytoskeleton"	"8"	"0"	"135.0"	"153.6"	"492.9"	"139.6"	"84.4"	"86.7"	"512.8"	"146.5"	"224.0"	"433.9"	"890.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46013"	"Proliferation marker protein Ki-67 OS=Homo sapiens OX=9606 GN=MKI67 PE=1 SV=2"	"2"	"2"	"4"	"2"	"3256"	"358.5"	"9.45"	"709.57"	"5.88"	"2"	"2"	"cell cycle OR cell proliferation;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00498, Pf08065, Pf15276"	"4288"	"ENSG00000148773"	"MKI67"	"hsa:4288; P46013; Q5VWH2"	""	"Primary focal segmental glomerulosclerosis (FSGS)"	"1"	"0"	"49.7"	"31.0"	"118.8"	"35.5"	"36.1"	"33.4"	"167.2"	"39.7"	"58.2"	"51.6"	"47.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NR28"	"Diablo homolog, mitochondrial OS=Homo sapiens OX=9606 GN=DIABLO PE=1 SV=1"	"13"	"2"	"3"	"2"	"239"	"27.1"	"5.90"	"870.93"	"5.87"	"2"	"1"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion"	""	"Pf09057"	"56616"	"ENSG00000184047"	"DIABLO"	"B2RDQ0; hsa:56616; Q6W3F3; Q96LV0; Q9BT11; Q9HAV6; Q9NR28"	"SMAC (DIABLO) binds to IAPs ; SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes ; Regulation of the apoptosome activity; Release of apoptotic factors from the mitochondria"	"Apoptosis modulation and signaling; TNF-alpha signaling pathway; Nanomaterial induced apoptosis; Apoptosis; Complement system in neuronal development and plasticity"	"10"	"0"	"129.1"	"158.9"	"480.5"	"147.8"	"146.0"	"125.9"	"343.9"	"57.5"	"87.3"	"68.6"	"76.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30876"	"DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1"	"2"	"2"	"4"	"2"	"1174"	"133.8"	"6.87"	"661.07"	"5.87"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00562, Pf04560, Pf04561, Pf04563, Pf04565, Pf04566, Pf04567"	"5431"	"ENSG00000047315"	"POLR2B"	"A8K1A8; hsa:5431; P30876; Q8IZ61"	"mRNA Splicing - Major Pathway; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"Pyrimidine metabolism; Eukaryotic transcription initiation"	"43"	"0"	"77.9"	"71.0"	"216.7"	"83.7"	"82.2"	"73.0"	"242.2"	"44.3"	"91.6"	"86.9"	"87.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51452"	"Dual specificity protein phosphatase 3 OS=Homo sapiens OX=9606 GN=DUSP3 PE=1 SV=1"	"13"	"2"	"4"	"2"	"185"	"20.5"	"7.80"	"844.42"	"5.87"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00782"	"1845"	"ENSG00000108861"	"DUSP3"	"D3DX45; hsa:1845; P51452; Q5U0J1; Q8IYJ9"	"ERKs are inactivated"	"MAPK signaling pathway; Fragile X syndrome"	"3"	"0"	"18.8"	"36.3"	"138.1"	"28.5"	"28.8"	"18.5"	"162.6"	"20.3"	"18.4"	"14.6"	"19.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95825"	"Quinone oxidoreductase-like protein 1 OS=Homo sapiens OX=9606 GN=CRYZL1 PE=1 SV=2"	"9"	"2"	"4"	"2"	"349"	"38.7"	"5.78"	"797.81"	"5.85"	"2"	"2"	"other metabolic processes"	""	"other molecular function"	""	"9946"	"ENSG00000205758"	"CRYZL1"	"B2RDX1; B3KQ77; hsa:9946; O95825; Q96DY0; Q9NVY7"	""	""	"0"	"0"	"16.7"	"20.7"	"103.8"	"13.1"	"17.0"	"14.0"	"113.0"	"14.0"	"17.8"	"12.2"	"10.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H6S0"	"3'-5' RNA helicase YTHDC2 OS=Homo sapiens OX=9606 GN=YTHDC2 PE=1 SV=2"	"2"	"3"	"5"	"3"	"1430"	"160.1"	"8.40"	"905.57"	"5.85"	"3"	"2"	"cell cycle OR cell proliferation;other biological processes"	"ER/Golgi;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf01424, Pf04146, Pf04408, Pf07717"	"64848"	"ENSG00000047188"	"YTHDC2"	"B2RP66; hsa:64848; Q9H6S0"	""	""	"0"	"0"	"73.1"	"71.3"	"228.1"	"69.9"	"77.4"	"51.8"	"193.1"	"18.0"	"35.7"	"20.2"	"23.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P56537"	"Eukaryotic translation initiation factor 6 OS=Homo sapiens OX=9606 GN=EIF6 PE=1 SV=1"	"10"	"2"	"3"	"2"	"245"	"26.6"	"4.68"	"281.99"	"5.84"	"1"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf01912"	"3692"	"ENSG00000242372"	"EIF6"	"B7ZBG9; hsa:3692; P56537; Q6IBN8; Q96TD5"	""	"Translation factors; Genetic causes of porto-sinusoidal vascular disease"	"2"	"0"	"104.3"	"99.1"	"323.5"	"99.3"	"110.8"	"88.4"	"338.0"	"55.2"	"91.4"	"72.9"	"67.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31944"	"Caspase-14 OS=Homo sapiens OX=9606 GN=CASP14 PE=1 SV=2"	"11"	"2"	"4"	"2"	"242"	"27.7"	"5.58"	"581.05"	"5.80"	"2"	"2"	"protein metabolism;other biological processes"	"plasma membrane;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00656"	"23581"	"ENSG00000105141"	"CASP14"	"hsa:23581; O95823; P31944; Q3SYC9"	"Formation of the cornified envelope"	"Vitamin D receptor pathway"	"2"	"0"	"15.2"	"11.7"	"16.8"	"7.0"	"6.6"	"6.4"	"22.9"	"8.4"	"10.2"	"10.1"	"16.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O76021"	"Ribosomal L1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RSL1D1 PE=1 SV=3"	"6"	"2"	"3"	"2"	"490"	"54.9"	"10.13"	"546.97"	"5.80"	"1"	"2"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00687"	"26156"	"ENSG00000171490"	"RSL1D1"	"B4DJ58; D3DUG7; hsa:26156; O76021; Q2M1T7; Q6PL22; Q8IWS7; Q8WUZ1; Q9HDA9; Q9Y3Z9"	""	""	"0"	"0"	"7.1"	"7.7"	"27.5"	"12.9"	"11.0"	"2.9"	"45.1"	"5.1"	"8.2"	"4.2"	"4.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96A65"	"Exocyst complex component 4 OS=Homo sapiens OX=9606 GN=EXOC4 PE=1 SV=1"	"4"	"3"	"5"	"3"	"974"	"110.4"	"6.49"	"808.57"	"5.80"	"3"	"2"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf04048"	"60412"	"ENSG00000131558"	"EXOC4"	"E9PED2; hsa:60412; Q541U8; Q96A65; Q9C0G4; Q9H9K0; Q9P102"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"Ciliary landscape"	"4"	"0"	"89.2"	"98.7"	"320.9"	"82.7"	"89.3"	"84.8"	"315.1"	"59.7"	"161.5"	"199.0"	"148.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7L0Y3"	"tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2"	"5"	"2"	"4"	"2"	"403"	"47.3"	"9.36"	"649.89"	"5.79"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01746"	"54931"	"ENSG00000174173"	"TRMT10C"	"hsa:54931; Q7L0Y3; Q9NRG5; Q9NX54; Q9Y596"	"tRNA processing in the mitochondrion; tRNA modification in the mitochondrion; rRNA processing in the mitochondrion"	""	"3"	"0"	"122.6"	"141.5"	"391.8"	"117.7"	"125.8"	"98.1"	"433.9"	"93.7"	"144.1"	"156.4"	"211.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00541"	"Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1"	"4"	"2"	"4"	"2"	"588"	"68.0"	"7.33"	"673.77"	"5.79"	"2"	"2"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf06732, Pf16589"	"23481"	"ENSG00000100029"	"PES1"	"hsa:23481; O00541; Q6IC29"	"Major pathway of rRNA processing in the nucleolus and cytosol"	""	"1"	"0"	"61.7"	"77.8"	"222.8"	"55.9"	"41.4"	"47.5"	"199.8"	"25.5"	"27.1"	"26.5"	"21.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15417"	"Calponin-3 OS=Homo sapiens OX=9606 GN=CNN3 PE=1 SV=1"	"14"	"4"	"6"	"4"	"329"	"36.4"	"6.05"	"1158.90"	"5.79"	"4"	"2"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00402"	"1266"	"ENSG00000117519"	"CNN3"	"B4DFK6; B4DP09; F8WA86; hsa:1266; Q15417; Q6FHA7"	""	""	"0"	"0"	"380.4"	"268.0"	"1006.6"	"230.3"	"199.5"	"159.2"	"1183.1"	"143.2"	"172.5"	"150.7"	"140.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H7E9"	"UPF0488 protein C8orf33 OS=Homo sapiens OX=9606 GN=C8orf33 PE=1 SV=1"	"10"	"2"	"3"	"2"	"229"	"25.0"	"9.95"	"290.16"	"5.78"	"1"	"2"	""	""	""	"Pf15393"	"65265"	"ENSG00000182307"	"C8orf33"	"A6NGC0; hsa:65265; Q96BT8; Q9H7E9"	""	""	"0"	"0"	"92.6"	"88.2"	"301.8"	"92.9"	"107.1"	"83.6"	"314.4"	"56.5"	"87.9"	"76.6"	"94.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O96019"	"Actin-like protein 6A OS=Homo sapiens OX=9606 GN=ACTL6A PE=1 SV=1"	"7"	"2"	"4"	"2"	"429"	"47.4"	"5.60"	"650.87"	"5.77"	"2"	"2"	"cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00022"	"86"	"ENSG00000136518"	"ACTL6A"	"B3KMN1; D3DNR9; hsa:86; O96019; Q8TAE5; Q9BVS8; Q9H0W6"	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; RMTs methylate histone arginines; UCH proteinases; HATs acetylate histones; DNA Damage Recognition in GG-NER"	"Androgen receptor network in prostate cancer; Gastric cancer network 1; Tumor suppressor activity of SMARCB1; Thermogenesis; Kleefstra syndrome"	"10"	"0"	"33.8"	"36.1"	"92.5"	"28.1"	"32.9"	"27.4"	"114.6"	"19.7"	"30.9"	"22.1"	"14.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NYR9"	"NF-kappa-B inhibitor-interacting Ras-like protein 2 OS=Homo sapiens OX=9606 GN=NKIRAS2 PE=1 SV=1"	"12"	"2"	"4"	"2"	"191"	"21.5"	"8.05"	"590.15"	"5.76"	"2"	"2"	"stress response;developmental processes;signal transduction;other biological processes"	"other cell component"	"other molecular function"	"Pf00071"	"28511"	"ENSG00000168256"	"NKIRAS2"	"A6NCZ5; B3KNN0; B4DNM3; hsa:28511; Q6PK52; Q96KC7; Q9NSX1; Q9NYR9"	"RIP-mediated NFkB activation via ZBP1; TAK1-dependent IKK and NF-kappa-B activation  ; TRAF6 mediated NF-kB activation"	""	"3"	"0"	"13.4"	"24.5"	"74.8"	"18.3"	"18.6"	"10.7"	"65.7"	"15.2"	"56.3"	"57.2"	"64.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92530"	"Proteasome inhibitor PI31 subunit OS=Homo sapiens OX=9606 GN=PSMF1 PE=1 SV=2"	"17"	"3"	"4"	"3"	"271"	"29.8"	"5.74"	"783.37"	"5.76"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf08577, Pf11566"	"9491"	"ENSG00000125818"	"PSMF1"	"A0AVQ9; D3DVW3; hsa:9491; Q92530; Q9H4I1"	"Separation of Sister Chromatids; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	""	"59"	"0"	"68.4"	"128.8"	"315.5"	"126.1"	"131.2"	"116.6"	"368.4"	"102.8"	"149.3"	"104.0"	"107.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13177"	"Serine/threonine-protein kinase PAK 2 OS=Homo sapiens OX=9606 GN=PAK2 PE=1 SV=3"	"4"	"2"	"3"	"2"	"524"	"58.0"	"5.96"	"325.26"	"5.75"	"1"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069, Pf00786"	"5062"	"ENSG00000180370"	"PAK2"	"hsa:5062; Q13154; Q13177; Q6ISC3"	"Regulation of activated PAK-2p34 by proteasome mediated degradation; MAPK6/MAPK4 signaling; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOJ GTPase cycle; RHOH GTPase cycle; RHOV GTPase cycle; Smooth Muscle Contraction; FCERI mediated MAPK activation; Generation of second messenger molecules; Regulation of PAK-2p34 activity by PS-GAP/RHG10; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; RHOU GTPase cycle; Ephrin signaling; Sema3A PAK dependent Axon repulsion; RHO GTPases activate PAKs; VEGFR2 mediated vascular permeability; Activation of RAC1; CD209 (DC-SIGN) signaling; CD28 dependent Vav1 pathway; Nef and signal transduction; Stimulation of the cell death response by PAK-2p34"	"Integrin-mediated cell adhesion; Apoptosis-related network due to altered Notch3 in ovarian cancer; Focal adhesion; Fas ligand pathway and stress induction of heat shock proteins; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Ras signaling; Pancreatic adenocarcinoma pathway; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-Merlin signaling dysregulation; Neural crest cell migration during development; Neural crest cell migration in cancer; 3q29 copy number variation syndrome; Pleural mesothelioma; Regulation of actin cytoskeleton; ErbB signaling pathway"	"43"	"0"	"61.6"	"76.5"	"342.9"	"67.7"	"73.0"	"49.0"	"327.7"	"41.4"	"49.8"	"48.7"	"30.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TEM1"	"Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3"	"1"	"2"	"4"	"2"	"1887"	"205.0"	"6.81"	"789.23"	"5.75"	"2"	"2"	"transport"	"other membranes;ER/Golgi;nucleus"	""	"Pf02368"	"23225"	"ENSG00000132182"	"NUP210"	"A6NN56; hsa:23225; O94980; Q6NXG6; Q8NBJ1; Q8TEM1; Q9H6C8; Q9UFP3"	"ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; snRNP Assembly; Regulation of HSF1-mediated heat shock response; SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of DNA replication proteins; HCMV Late Events; SUMOylation of RNA binding proteins; HCMV Early Events; Transcriptional regulation by small RNAs; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; SUMOylation of SUMOylation proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses"	""	"28"	"0"	"81.5"	"99.8"	"342.3"	"80.3"	"85.6"	"49.7"	"354.5"	"26.0"	"46.8"	"29.9"	"23.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UHJ6"	"Sedoheptulokinase OS=Homo sapiens OX=9606 GN=SHPK PE=1 SV=3"	"7"	"2"	"3"	"2"	"478"	"51.5"	"6.83"	"287.87"	"5.73"	"1"	"2"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"8.1"	"8.6"	"30.7"	"5.1"	"8.8"	"6.1"	"34.4"	"5.1"	"5.7"	"6.7"	"5.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H910"	"Jupiter microtubule associated homolog 2 OS=Homo sapiens OX=9606 GN=JPT2 PE=1 SV=1"	"12"	"2"	"4"	"2"	"190"	"20.1"	"9.26"	"685.43"	"5.73"	"2"	"2"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	""	"Pf17054"	"90861"	"ENSG00000206053"	"JPT2"	"B1AJY2; B4DLH4; hsa:90861; Q6EIC7; Q9H910"	""	""	"0"	"0"	"71.0"	"50.5"	"128.3"	"51.2"	"57.6"	"44.3"	"157.7"	"38.0"	"49.3"	"44.7"	"31.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13907"	"Isopentenyl-diphosphate Delta-isomerase 1 OS=Homo sapiens OX=9606 GN=IDI1 PE=1 SV=2"	"9"	"2"	"4"	"2"	"227"	"26.3"	"6.34"	"642.32"	"5.71"	"2"	"2"	"other metabolic processes"	"cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00293"	"3422"	"ENSG00000067064"	"IDI1"	"B4E155; hsa:3422; Q13907; Q32Q13; Q53GQ6; Q86U81; Q8WUX8; Q96IZ4; Q9BQ74"	"Activation of gene expression by SREBF (SREBP); Cholesterol biosynthesis"	"Target of rapamycin signaling; Cholesterol biosynthesis pathway; Sterol regulatory element-binding proteins (SREBP) signaling; Exercise-induced circadian regulation; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Cholesterol synthesis disorders; Cholesterol metabolism; Cholesterol biosynthesis pathway in hepatocytes; Enterocyte cholesterol metabolism"	"11"	"0"	"60.2"	"74.9"	"303.2"	"64.0"	"72.3"	"46.4"	"303.8"	"43.2"	"51.5"	"47.1"	"42.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96RP9"	"Elongation factor G, mitochondrial OS=Homo sapiens OX=9606 GN=GFM1 PE=1 SV=2"	"3"	"2"	"5"	"2"	"751"	"83.4"	"7.01"	"895.59"	"5.71"	"2"	"1"	"protein metabolism;other metabolic processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf00679, Pf03144, Pf03764, Pf14492"	"85476"	"ENSG00000168827"	"GFM1"	"A6NCI9; B2RCB9; B3KRW1; hsa:85476; Q6GTN2; Q96RP9; Q96T39"	"Mitochondrial translation elongation"	""	"1"	"0"	"81.4"	"94.7"	"334.2"	"97.8"	"95.3"	"49.8"	"428.9"	"43.7"	"69.8"	"57.2"	"62.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UJX3"	"Anaphase-promoting complex subunit 7 OS=Homo sapiens OX=9606 GN=ANAPC7 PE=1 SV=4"	"4"	"2"	"3"	"2"	"599"	"66.8"	"5.64"	"406.56"	"5.71"	"1"	"2"	""	""	""	"Pf13432"	"51434"	""	"ANAPC7"	"A0A024RBJ3; hsa:51434"	""	""	"0"	"0"	"72.4"	"76.0"	"214.0"	"68.5"	"59.3"	"41.3"	"263.7"	"27.5"	"50.9"	"40.5"	"43.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96P70"	"Importin-9 OS=Homo sapiens OX=9606 GN=IPO9 PE=1 SV=3"	"2"	"2"	"4"	"2"	"1041"	"115.9"	"4.81"	"831.28"	"5.71"	"2"	"2"	"transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf03810"	"55705"	"ENSG00000198700"	"IPO9"	"B1ASV5; hsa:55705; Q8N1Y1; Q8N3I2; Q8NCG9; Q96P70; Q96SU6; Q9NW01; Q9P0A8; Q9ULM8"	""	""	"0"	"0"	"73.0"	"58.2"	"196.7"	"51.0"	"52.8"	"40.6"	"289.9"	"29.0"	"34.5"	"33.1"	"30.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13242"	"Serine/arginine-rich splicing factor 9 OS=Homo sapiens OX=9606 GN=SRSF9 PE=1 SV=1"	"12"	"2"	"3"	"2"	"221"	"25.5"	"8.65"	"402.57"	"5.70"	"1"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00076"	"8683"	"ENSG00000111786"	"SRSF9"	"hsa:8683; Q13242; Q52LD1"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"mRNA processing"	"6"	"0"	"124.3"	"143.0"	"360.6"	"121.0"	"131.5"	"114.0"	"420.8"	"83.9"	"125.0"	"107.3"	"121.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15226"	"NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2"	"4"	"3"	"5"	"3"	"690"	"77.6"	"8.79"	"952.48"	"5.70"	"3"	"2"	"RNA metabolism OR transcription;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01424, Pf01585"	"55922"	"ENSG00000186416"	"NKRF"	"G3V1N1; hsa:55922; O15226; Q4VC41; Q9UJ91"	""	"Pathogenesis of SARS-CoV-2 mediated by nsp9-nsp10 complex; Network map of SARS-CoV-2 signaling pathway"	"2"	"0"	"19.2"	"21.9"	"80.9"	"22.7"	"19.0"	"18.8"	"91.6"	"10.5"	"15.2"	"7.5"	"10.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TAE8"	"Growth arrest and DNA damage-inducible proteins-interacting protein 1 OS=Homo sapiens OX=9606 GN=GADD45GIP1 PE=1 SV=1"	"5"	"1"	"4"	"1"	"222"	"25.4"	"10.02"	"574.89"	"5.70"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	""	"Pf10147"	"90480"	"ENSG00000179271"	"GADD45GIP1"	"hsa:90480; Q8IVM3; Q8TAE8; Q8TE51; Q969P9; Q9BSM6"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"66.7"	"80.1"	"237.8"	"66.8"	"81.6"	"66.1"	"245.3"	"51.5"	"130.1"	"125.8"	"139.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7RTP6"	"[F-actin]-monooxygenase MICAL3 OS=Homo sapiens OX=9606 GN=MICAL3 PE=1 SV=2"	"2"	"3"	"5"	"3"	"2002"	"224.2"	"5.55"	"906.28"	"5.68"	"3"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00412, Pf01494, Pf12130"	"57553"	"ENSG00000243156"	"MICAL3"	"B2RXJ5; E9PEF0; hsa:57553; O94909; Q5U4P4; Q6ICK4; Q7RTP6; Q96DF2; Q9P2I3"	""	""	"0"	"0"	"12.4"	"10.1"	"37.0"	"12.4"	"4.3"	"9.4"	"36.6"	"17.4"	"72.5"	"127.8"	"146.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q93034"	"Cullin-5 OS=Homo sapiens OX=9606 GN=CUL5 PE=1 SV=4"	"3"	"2"	"4"	"2"	"780"	"90.9"	"7.94"	"666.42"	"5.68"	"2"	"2"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;transport;signal transduction"	"cytosol;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf00888, Pf10557"	"8065"	"ENSG00000166266"	"CUL5"	"A8K960; hsa:8065; O14766; Q93034; Q9BZC6"	"Antigen processing: Ubiquitination & Proteasome degradation; Vif-mediated degradation of APOBEC3G; Neddylation; Inactivation of CSF3 (G-CSF) signaling; Downregulation of ERBB2 signaling"	"Apoptosis-related network due to altered Notch3 in ovarian cancer; Dual hijack model of Vif in HIV infection; Modulators of TCR signaling and T cell activation"	"8"	"0"	"63.4"	"62.9"	"293.6"	"75.0"	"47.3"	"28.7"	"286.6"	"31.1"	"54.5"	"49.0"	"53.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P54725"	"UV excision repair protein RAD23 homolog A OS=Homo sapiens OX=9606 GN=RAD23A PE=1 SV=1"	"9"	"3"	"4"	"1"	"363"	"39.6"	"4.58"	"628.54"	"5.68"	"2"	"2"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00240, Pf00627, Pf09280"	"5886"	"ENSG00000179262"	"RAD23A"	"hsa:5886; K7ESE3; P54725; Q59EU8; Q5M7Z1"	"Josephin domain DUBs; Formation of Incision Complex in GG-NER; DNA Damage Recognition in GG-NER"	"Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"6"	"0"	"48.2"	"59.0"	"168.2"	"61.1"	"68.9"	"63.4"	"174.7"	"47.5"	"62.5"	"56.0"	"57.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14CX7"	"N-alpha-acetyltransferase 25, NatB auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA25 PE=1 SV=1"	"3"	"3"	"5"	"3"	"972"	"112.2"	"6.64"	"1074.02"	"5.67"	"3"	"2"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;other cell component"	""	"Pf09797"	"80018"	"ENSG00000111300"	"NAA25"	"A0JLU7; hsa:80018; Q14CX7; Q6MZH1; Q7Z4N6; Q9H911"	""	""	"0"	"0"	"98.1"	"113.0"	"431.8"	"96.7"	"85.9"	"66.4"	"357.1"	"45.5"	"68.0"	"82.3"	"119.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62942"	"Peptidyl-prolyl cis-trans isomerase FKBP1A OS=Homo sapiens OX=9606 GN=FKBP1A PE=1 SV=2"	"34"	"2"	"2"	"2"	"108"	"11.9"	"8.16"	"371.82"	"5.66"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00254"	"2280"	"ENSG00000088832"	"FKBP1A"	"D3DVW6; hsa:2280; P20071; P62942; Q4VC47; Q6FGD9; Q6LEU3; Q9H103; Q9H566"	"Potential therapeutics for SARS; mTORC1-mediated signalling; SARS-CoV-1 activates/modulates innate immune responses; TGF-beta receptor signaling activates SMADs; Calcineurin activates NFAT; TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition); TGFBR1 LBD Mutants in Cancer"	"Target of rapamycin signaling; Spinal cord injury; Head and neck squamous cell carcinoma; TGF-beta receptor signaling in skeletal dysplasias; Disturbed pathways in Duchenne Muscular Dystrophy; Calcium regulation in cardiac cells; TGF-beta receptor signaling"	"14"	"0"	"42.7"	"49.4"	"252.5"	"48.5"	"46.0"	"36.9"	"296.1"	"33.5"	"40.1"	"30.8"	"29.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4E8"	"Ubiquitin carboxyl-terminal hydrolase 15 OS=Homo sapiens OX=9606 GN=USP15 PE=1 SV=3"	"3"	"3"	"5"	"3"	"981"	"112.3"	"5.22"	"873.60"	"5.65"	"3"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00443, Pf06337, Pf14533, Pf14836"	"9958"	"ENSG00000135655"	"USP15"	"hsa:9958; Q08AL5; Q9H8G9; Q9HCA6; Q9UNP0; Q9Y4E8; Q9Y5B5"	"Ub-specific processing proteases; UCH proteinases; Downregulation of TGF-beta receptor signaling"	""	"3"	"0"	"223.5"	"244.9"	"596.8"	"225.6"	"233.7"	"215.7"	"675.7"	"172.9"	"237.4"	"179.8"	"196.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q08257"	"Quinone oxidoreductase OS=Homo sapiens OX=9606 GN=CRYZ PE=1 SV=1"	"3"	"1"	"3"	"1"	"329"	"35.2"	"8.44"	"327.58"	"5.64"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"cytosol"	"nucleic acid binding activity;other molecular function"	"Pf08240, Pf13602"	"1429"	"ENSG00000116791"	"CRYZ"	"A6NN60; D3DQ76; hsa:1429; Q08257; Q53FT0; Q59EU7; Q5HYE7; Q6NSK9"	""	""	"0"	"0"	"61.7"	"66.5"	"168.0"	"68.0"	"58.4"	"42.9"	"215.3"	"43.7"	"56.8"	"43.9"	"42.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6UXN9"	"WD repeat-containing protein 82 OS=Homo sapiens OX=9606 GN=WDR82 PE=1 SV=1"	"7"	"1"	"1"	"1"	"313"	"35.1"	"7.69"	""	"5.63"	""	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00400"	"80335"	"ENSG00000164091"	"WDR82"	"A8K5R5; hsa:80335; Q6UXN9; Q8TEB2"	"Formation of WDR5-containing histone-modifying complexes"	""	"1"	"0"	"35.6"	"34.5"	"97.9"	"41.1"	"33.1"	"31.0"	"99.9"	"25.6"	"35.0"	"34.8"	"35.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96E11"	"Ribosome-recycling factor, mitochondrial OS=Homo sapiens OX=9606 GN=MRRF PE=1 SV=1"	"8"	"1"	"1"	"1"	"262"	"29.3"	"9.79"	""	"5.62"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"mitochondrion"	"translation activity"	"Pf01765"	"92399"	"ENSG00000148187"	"MRRF"	"A8K6D8; A8K6Z4; B7Z4X5; B7Z6P7; hsa:92399; Q5RKT1; Q5T7T0; Q5T7T1; Q5T7T2; Q5T7T3; Q5T7T4; Q5T7T5; Q96E11"	"Mitochondrial translation termination"	""	"1"	"0"	"10.0"	"10.3"	"33.5"	"9.2"	"6.0"	"5.8"	"21.7"	"0.0"	"6.8"	"11.0"	"15.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92796"	"Disks large homolog 3 OS=Homo sapiens OX=9606 GN=DLG3 PE=1 SV=2"	"2"	"1"	"2"	"1"	"817"	"90.3"	"7.03"	"530.19"	"5.62"	"1"	"1"	"cell-cell signaling;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00018, Pf00595, Pf00625, Pf10600"	"1741"	"ENSG00000082458"	"DLG3"	"B4E0H1; D3DVU5; hsa:1741; Q5JUW6; Q5JUW7; Q92796; Q9ULI8"	"Assembly and cell surface presentation of NMDA receptors; RAF/MAP kinase cascade; Ras activation upon Ca2+ influx through NMDA receptor; Unblocking of NMDA receptors, glutamate binding and activation; Negative regulation of NMDA receptor-mediated neuronal transmission; Long-term potentiation; Neurexins and neuroligins; Synaptic adhesion-like molecules; NrCAM interactions; Activation of Ca-permeable Kainate Receptor"	""	"10"	"0"	"15.6"	"14.8"	"53.5"	"16.0"	"12.2"	"10.9"	"65.7"	"13.4"	"30.6"	"32.2"	"39.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96HS1"	"Serine/threonine-protein phosphatase PGAM5, mitochondrial OS=Homo sapiens OX=9606 GN=PGAM5 PE=1 SV=2"	"9"	"2"	"4"	"2"	"289"	"32.0"	"8.68"	"697.03"	"5.60"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion"	"enzyme regulator activity;other molecular function"	"Pf00300"	"192111"	"ENSG00000247077"	"PGAM5"	"A9LN06; C9IZY7; hsa:192111; Q96HS1; Q96JB0"	""	"NRF2-ARE regulation"	"1"	"0"	"63.6"	"66.7"	"283.2"	"65.7"	"59.1"	"49.5"	"358.1"	"31.0"	"50.6"	"31.6"	"35.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92879"	"CUGBP Elav-like family member 1 OS=Homo sapiens OX=9606 GN=CELF1 PE=1 SV=2"	"4"	"1"	"2"	"1"	"486"	"52.0"	"8.46"	"612.99"	"5.60"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"10658"	"ENSG00000149187"	"CELF1"	"B4E2U5; D3DQS0; F8W940; hsa:10658; Q4LE52; Q92879; Q9NP83; Q9NR06"	""	"Adipogenesis; mRNA processing"	"2"	"0"	"23.5"	"19.4"	"70.7"	"21.5"	"19.2"	"19.6"	"95.2"	"13.8"	"17.4"	"10.7"	"13.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H4A4"	"Aminopeptidase B OS=Homo sapiens OX=9606 GN=RNPEP PE=1 SV=2"	"3"	"2"	"4"	"2"	"650"	"72.5"	"5.74"	"603.30"	"5.59"	"2"	"2"	"protein metabolism"	"non-structural extracellular;plasma membrane;other membranes"	"other molecular function"	"Pf01433, Pf09127, Pf17900"	"6051"	"ENSG00000176393"	"RNPEP"	"hsa:6051; Q9BVM9; Q9H1D4; Q9H4A4; Q9NPT7"	""	""	"0"	"0"	"24.8"	"38.0"	"208.6"	"31.5"	"26.7"	"22.2"	"279.2"	"16.5"	"21.3"	"17.6"	"14.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P36405"	"ADP-ribosylation factor-like protein 3 OS=Homo sapiens OX=9606 GN=ARL3 PE=1 SV=2"	"13"	"2"	"4"	"2"	"182"	"20.4"	"7.24"	"642.95"	"5.58"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytoskeleton;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00025"	"403"	"ENSG00000138175"	"ARL3"	"B2R6C7; hsa:403; P36405; Q53X83; Q5JSM2"	"Trafficking of myristoylated proteins to the cilium"	"Genes related to primary cilium development (based on CRISPR); Joubert syndrome; Ciliopathies; Bardet-Biedl syndrome"	"5"	"0"	"21.9"	"17.7"	"114.4"	"15.7"	"18.1"	"6.7"	"185.8"	"10.2"	"8.8"	"13.8"	"8.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q09161"	"Nuclear cap-binding protein subunit 1 OS=Homo sapiens OX=9606 GN=NCBP1 PE=1 SV=1"	"3"	"2"	"4"	"2"	"790"	"91.8"	"6.43"	"743.64"	"5.58"	"2"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02854, Pf09088, Pf09090"	"4686"	"ENSG00000136937"	"NCBP1"	"B2R718; hsa:4686; Q09161; Q59G76; Q5T1V0; Q5T7X2"	"mRNA Splicing - Major Pathway; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Abortive elongation of HIV-1 transcript in the absence of Tat; RNA Polymerase II Pre-transcription Events; RNA polymerase II transcribes snRNA genes; mRNA Capping; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Signaling by FGFR2 IIIa TM; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; snRNP Assembly; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"mRNA processing; 3q29 copy number variation syndrome"	"29"	"0"	"95.6"	"108.2"	"325.5"	"91.2"	"74.7"	"52.9"	"320.3"	"42.0"	"54.6"	"38.3"	"41.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UHB6"	"LIM domain and actin-binding protein 1 OS=Homo sapiens OX=9606 GN=LIMA1 PE=1 SV=1"	"3"	"2"	"4"	"2"	"759"	"85.2"	"6.84"	"608.52"	"5.58"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412"	"51474"	"ENSG00000050405"	"LIMA1"	"B2RB09; hsa:51474; Q2TAN7; Q59FE8; Q9BVF2; Q9H8J1; Q9HBN5; Q9NX96; Q9NXC3; Q9NXU6; Q9P0H8; Q9UHB5; Q9UHB6"	""	""	"0"	"0"	"42.2"	"41.0"	"102.2"	"36.8"	"35.6"	"28.8"	"102.1"	"19.4"	"28.7"	"23.3"	"16.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13796"	"Plastin-2 OS=Homo sapiens OX=9606 GN=LCP1 PE=1 SV=6"	"6"	"3"	"5"	"1"	"627"	"70.2"	"5.43"	"1249.96"	"5.57"	"3"	"2"	"cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00036, Pf00307"	"3936"	"ENSG00000136167"	"LCP1"	"B2R613; B4DUA0; hsa:3936; P13796; Q5TBN4"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	""	"1"	"0"	"2.1"	"4.1"	"34.2"	"8.2"	"5.1"	"4.2"	"54.6"	"2.7"	"3.5"	"4.2"	"3.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UQN3"	"Charged multivesicular body protein 2b OS=Homo sapiens OX=9606 GN=CHMP2B PE=1 SV=1"	"8"	"2"	"4"	"2"	"213"	"23.9"	"8.76"	"683.70"	"5.57"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf03357"	"25978"	"ENSG00000083937"	"CHMP2B"	"B4DJG8; hsa:25978; Q53HC7; Q9UQN3; Q9Y4U6"	"Pyroptosis; Budding and maturation of HIV virion; Endosomal Sorting Complex Required For Transport (ESCRT); Late endosomal microautophagy; Macroautophagy; HCMV Late Events; Sealing of the nuclear envelope (NE) by ESCRT-III; Translation of Replicase and Assembly of the Replication Transcription Complex; Translation of Replicase and Assembly of the Replication Transcription Complex"	""	"9"	"0"	"263.1"	"281.6"	"717.7"	"268.5"	"252.4"	"237.3"	"748.1"	"190.0"	"298.9"	"225.9"	"273.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P20338"	"Ras-related protein Rab-4A OS=Homo sapiens OX=9606 GN=RAB4A PE=1 SV=3"	"10"	"2"	"4"	"1"	"218"	"24.4"	"6.07"	"679.04"	"5.57"	"2"	"2"	"transport;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00071"	"5867"	"ENSG00000168118"	"RAB4A"	"hsa:5867; P20338; Q5T7P7; Q9BQ44"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; RAB geranylgeranylation; Synthesis of PIPs at the plasma membrane; TBC/RABGAPs; MET receptor recycling"	"VEGFA-VEGFR2 signaling; Insulin signaling; Intracellular trafficking proteins involved in CMT neuropathy; 16p11.2 distal deletion syndrome"	"9"	"0"	"10.3"	"13.2"	"54.8"	"12.9"	"8.8"	"5.5"	"64.4"	"6.1"	"8.8"	"5.3"	"4.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15126"	"Phosphomevalonate kinase OS=Homo sapiens OX=9606 GN=PMVK PE=1 SV=3"	"19"	"3"	"5"	"3"	"192"	"22.0"	"5.73"	"1148.97"	"5.57"	"3"	"2"	"other metabolic processes;other biological processes"	"cytosol;other cytoplasmic organelle"	"kinase activity;other molecular function"	"Pf04275"	"10654"	"ENSG00000163344"	"PMVK"	"hsa:10654; Q15126; Q5TZW9"	"Activation of gene expression by SREBF (SREBP); Cholesterol biosynthesis"	"Cholesterol biosynthesis pathway; Mevalonate pathway; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Cholesterol synthesis disorders; Cholesterol metabolism; Enterocyte cholesterol metabolism"	"8"	"0"	"119.5"	"128.3"	"496.0"	"116.5"	"112.5"	"77.9"	"600.3"	"105.1"	"179.2"	"361.4"	"1125.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14247"	"Src substrate cortactin OS=Homo sapiens OX=9606 GN=CTTN PE=1 SV=2"	"4"	"2"	"4"	"2"	"550"	"61.5"	"5.40"	"554.81"	"5.56"	"2"	"2"	"cell adhesion;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf02218, Pf14604"	"2017"	"ENSG00000085733; ENSG00000288401"	"CTTN"	"hsa:2017; Q14247; Q8N707; Q96H99"	"Clathrin-mediated endocytosis; RHO GTPases activate PAKs"	"Pathogenic Escherichia coli infection; Hepatitis C and hepatocellular carcinoma"	"4"	"0"	"162.8"	"164.6"	"554.6"	"186.8"	"166.8"	"140.8"	"637.3"	"100.4"	"159.7"	"117.0"	"100.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P59998"	"Actin-related protein 2/3 complex subunit 4 OS=Homo sapiens OX=9606 GN=ARPC4 PE=1 SV=3"	"11"	"2"	"4"	"2"	"168"	"19.7"	"8.43"	"748.33"	"5.55"	"2"	"2"	"cell organization and biogenesis"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf05856"	"10093"	"ENSG00000241553"	"ARPC4"	"C9JWM7; E7ETI0; F6TTL5; hsa:10093; O15509; P59998; Q6P0W5; Q96QJ3"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Clathrin-mediated endocytosis; EPHB-mediated forward signaling"	"Pathogenic Escherichia coli infection"	"6"	"0"	"199.2"	"185.0"	"702.2"	"163.7"	"103.6"	"89.3"	"684.7"	"177.8"	"319.7"	"717.4"	"1176.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16186"	"Proteasomal ubiquitin receptor ADRM1 OS=Homo sapiens OX=9606 GN=ADRM1 PE=1 SV=2"	"8"	"2"	"4"	"2"	"407"	"42.1"	"5.07"	"763.75"	"5.55"	"1"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf04683, Pf16550"	"11047"	"ENSG00000130706"	"ADRM1"	"A0PKB1; hsa:11047; Q16186; Q96FJ7; Q9H1P2"	"Ub-specific processing proteases; UCH proteinases"	"Alzheimer's disease and miRNA effects; Alzheimer's disease"	"4"	"0"	"80.3"	"73.5"	"340.2"	"71.2"	"58.6"	"41.1"	"372.3"	"30.7"	"33.0"	"31.6"	"33.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N122"	"Regulatory-associated protein of mTOR OS=Homo sapiens OX=9606 GN=RPTOR PE=1 SV=1"	"2"	"2"	"4"	"2"	"1335"	"148.9"	"6.89"	"593.89"	"5.55"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00400, Pf02985, Pf14538"	"57521"	"ENSG00000141564"	"RPTOR"	"B2RN36; C6KEF2; F5H7J5; hsa:57521; Q8N122; Q8N4V9; Q8TB32; Q9P2P3"	"TP53 Regulates Metabolic Genes; Amino acids regulate mTORC1; Regulation of PTEN gene transcription; mTORC1-mediated signalling; Macroautophagy; Energy dependent regulation of mTOR by LKB1-AMPK; HSF1-dependent transactivation"	"AMP-activated protein kinase signaling; Target of rapamycin signaling; PI3K-AKT-mTOR signaling pathway and therapeutic opportunities; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Clear cell renal cell carcinoma pathways; PI3K-Akt signaling pathway; Thermogenesis; Synaptic signaling pathways associated with autism spectrum disorder; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Head and neck squamous cell carcinoma; Thyroid hormones production and peripheral downstream signaling effects; IL-18 signaling pathway; CAMKK2 pathway; Autophagy; p53 transcriptional gene network; Pleural mesothelioma; Network map of SARS-CoV-2 signaling pathway; GDNF signaling; DYRK1A involvement regarding cell proliferation in brain development; JAK-STAT signaling in the regulation of Beta-cells; Interferon type I signaling pathways"	"33"	"0"	"22.1"	"13.2"	"69.3"	"18.0"	"15.2"	"11.0"	"65.6"	"14.5"	"17.6"	"16.5"	"16.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14908"	"PDZ domain-containing protein GIPC1 OS=Homo sapiens OX=9606 GN=GIPC1 PE=1 SV=2"	"5"	"1"	"4"	"1"	"333"	"36.0"	"6.28"	"738.16"	"5.55"	"1"	"1"	"cell-cell signaling;transport;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00595"	"10755"	"ENSG00000123159"	"GIPC1"	"A8K4I3; A8MZG3; hsa:10755; O14908; Q9BTC9"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"9.4"	"8.4"	"31.3"	"5.8"	"5.9"	"6.2"	"34.2"	"4.5"	"4.6"	"5.6"	"4.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35241"	"Radixin OS=Homo sapiens OX=9606 GN=RDX PE=1 SV=1"	"3"	"2"	"4"	"1"	"583"	"68.5"	"6.37"	"651.17"	"5.55"	"2"	"2"	"cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf00769, Pf09379, Pf09380, Pf20492"	"5962"	"ENSG00000137710"	"RDX"	"A7YIJ8; A7YIK0; A7YIK3; B7Z9U6; F5H1A7; hsa:5962; P35241; Q86Y61"	"Recycling pathway of L1; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea"	"Regulation of actin cytoskeleton"	"4"	"0"	"129.4"	"109.6"	"513.3"	"108.4"	"63.2"	"55.0"	"145.1"	"29.1"	"69.2"	"54.8"	"58.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O76094"	"Signal recognition particle subunit SRP72 OS=Homo sapiens OX=9606 GN=SRP72 PE=1 SV=3"	"2"	"1"	"4"	"1"	"671"	"74.6"	"9.26"	"665.70"	"5.55"	"1"	"1"	"transport"	"cytosol;ER/Golgi;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf08492, Pf13181, Pf17004"	"6731"	"ENSG00000174780"	"SRP72"	"G5E9Z8; hsa:6731; O76094; Q7Z3C0"	"SRP-dependent cotranslational protein targeting to membrane"	""	"1"	"0"	"68.3"	"62.8"	"268.3"	"50.5"	"37.2"	"35.7"	"235.0"	"13.5"	"23.8"	"18.7"	"21.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13596"	"Sorting nexin-1 OS=Homo sapiens OX=9606 GN=SNX1 PE=1 SV=3"	"5"	"2"	"3"	"2"	"522"	"59.0"	"5.15"	"425.56"	"5.55"	"1"	"2"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00787, Pf03700, Pf09325"	"6642"	"ENSG00000028528"	"SNX1"	"A6NM19; A8K6T7; H0Y2M5; hsa:6642; O60750; O60751; Q13596; Q6ZRJ8"	""	""	"0"	"0"	"66.5"	"56.2"	"343.5"	"66.6"	"51.0"	"39.4"	"264.0"	"22.2"	"37.9"	"29.5"	"29.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50750"	"Cyclin-dependent kinase 9 OS=Homo sapiens OX=9606 GN=CDK9 PE=1 SV=3"	"6"	"3"	"4"	"3"	"372"	"42.8"	"8.79"	"569.66"	"5.54"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00069"	"1025"	"ENSG00000136807"	"CDK9"	"hsa:1025; P50750; Q5JU24; Q5JU25; Q5U006; Q96TF1"	"Estrogen-dependent gene expression; SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; Interactions of Tat with host cellular proteins"	"MicroRNAs in cardiomyocyte hypertrophy; IL-9 signaling pathway; Cardiac hypertrophic response; Initiation of transcription and translation elongation at the HIV-1 LTR; Male infertility"	"20"	"0"	"66.3"	"60.0"	"182.1"	"59.0"	"44.9"	"45.0"	"218.0"	"31.4"	"48.5"	"48.2"	"58.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75940"	"Survival of motor neuron-related-splicing factor 30 OS=Homo sapiens OX=9606 GN=SMNDC1 PE=1 SV=1"	"9"	"2"	"4"	"2"	"238"	"26.7"	"7.24"	"683.92"	"5.54"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf06003"	"10285"	"ENSG00000119953"	"SMNDC1"	"B2RA27; D3DRB1; hsa:10285; O75940; Q5T3K6"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"50.4"	"49.7"	"180.1"	"51.3"	"61.9"	"48.6"	"260.4"	"48.2"	"95.0"	"101.6"	"144.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14787"	"Transportin-2 OS=Homo sapiens OX=9606 GN=TNPO2 PE=1 SV=3"	"5"	"5"	"8"	"1"	"897"	"101.3"	"5.01"	"1474.48"	"5.54"	"5"	"3"	"transport"	"nucleus;other cell component"	"other molecular function"	"Pf03810"	"30000"	"ENSG00000105576"	"TNPO2"	"hsa:30000; O14655; O14787; Q6IN77"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q96EB1"	"Elongator complex protein 4 OS=Homo sapiens OX=9606 GN=ELP4 PE=1 SV=2"	"6"	"1"	"1"	"1"	"424"	"46.6"	"8.51"	""	"5.53"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity"	"Pf05625"	"26610"	"ENSG00000109911"	"ELP4"	"B4E3W0; E7EPZ6; hsa:26610; Q96EB1; Q9H4E8; Q9NX11"	"HATs acetylate histones"	"Mesodermal commitment pathway"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q93096"	"Protein tyrosine phosphatase type IVA 1 OS=Homo sapiens OX=9606 GN=PTP4A1 PE=1 SV=2"	"24"	"2"	"3"	"2"	"173"	"19.8"	"8.97"	"288.80"	"5.52"	"1"	"2"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00782"	"7803"	"ENSG00000112245"	"PTP4A1"	"B2R6C8; hsa:7803; O00648; Q49A54; Q93096"	""	""	"0"	"0"	"7.2"	"9.3"	"35.4"	"13.7"	"7.2"	"4.4"	"48.0"	"5.9"	"12.6"	"9.9"	"12.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96NC0"	"Zinc finger matrin-type protein 2 OS=Homo sapiens OX=9606 GN=ZMAT2 PE=1 SV=1"	"9"	"2"	"4"	"2"	"199"	"23.6"	"9.01"	"662.43"	"5.52"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf12171"	"153527"	"ENSG00000146007"	"ZMAT2"	"hsa:153527; Q96NC0"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"186.3"	"201.0"	"465.6"	"165.2"	"172.1"	"171.6"	"684.4"	"188.2"	"316.7"	"267.9"	"349.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63279"	"SUMO-conjugating enzyme UBC9 OS=Homo sapiens OX=9606 GN=UBE2I PE=1 SV=1"	"8"	"1"	"2"	"1"	"158"	"18.0"	"8.66"	"550.62"	"5.50"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00179"	"7329"	"ENSG00000103275"	"UBE2I"	"D3DU69; hsa:7329; P50550; P63279; Q15698; Q59GX1; Q86VB3"	"SUMOylation of RNA binding proteins; Formation of Incision Complex in GG-NER; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; Meiotic synapsis; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of DNA replication proteins; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; SUMOylation of intracellular receptors; Processing of DNA double-strand break ends; Vitamin D (calciferol) metabolism; SUMOylation of transcription factors; Postmitotic nuclear pore complex (NPC) reformation; Negative regulation of activity of TFAP2 (AP-2) family transcription factors; Maturation of nucleoprotein; SUMOylation of immune response proteins; SUMOylation of nuclear envelope proteins; Maturation of nucleoprotein; SUMO is transferred from E1 to E2 (UBE2I, UBC9)"	"Androgen receptor signaling pathway"	"24"	"0"	"60.3"	"62.9"	"307.1"	"92.7"	"92.1"	"85.0"	"718.2"	"68.9"	"259.9"	"645.4"	"1772.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13151"	"Heterogeneous nuclear ribonucleoprotein A0 OS=Homo sapiens OX=9606 GN=HNRNPA0 PE=1 SV=1"	"9"	"4"	"11"	"2"	"305"	"30.8"	"9.29"	"2763.14"	"5.50"	"4"	"2"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"10949"	"ENSG00000177733"	"HNRNPA0"	"hsa:10949; Q13151; Q6IB18"	""	""	"0"	"0"	"398.1"	"437.3"	"1218.7"	"370.1"	"337.2"	"305.1"	"1431.1"	"236.9"	"304.1"	"271.0"	"317.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WXX5"	"DnaJ homolog subfamily C member 9 OS=Homo sapiens OX=9606 GN=DNAJC9 PE=1 SV=1"	"16"	"3"	"6"	"3"	"260"	"29.9"	"5.73"	"1237.77"	"5.49"	"3"	"2"	"cell organization and biogenesis;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00226"	"23234"	"ENSG00000213551"	"DNAJC9"	"B2RMW6; hsa:23234; Q8WXX5"	""	""	"0"	"0"	"130.9"	"142.4"	"523.5"	"142.5"	"144.0"	"128.3"	"649.9"	"103.3"	"159.1"	"136.2"	"141.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31153"	"S-adenosylmethionine synthase isoform type-2 OS=Homo sapiens OX=9606 GN=MAT2A PE=1 SV=1"	"5"	"2"	"4"	"2"	"395"	"43.6"	"6.48"	"639.42"	"5.49"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00438, Pf02772, Pf02773"	"4144"	"ENSG00000168906"	"MAT2A"	"A8K511; B4DN45; D6W5L1; hsa:4144; P31153; Q53SP5"	"Methylation"	"Trans-sulfuration, one-carbon metabolism and related pathways; Methionine de novo and salvage pathway; Methylation pathways"	"4"	"0"	"103.4"	"116.8"	"350.7"	"103.2"	"94.9"	"72.5"	"486.2"	"91.1"	"108.9"	"82.2"	"73.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60784"	"Target of Myb protein 1 OS=Homo sapiens OX=9606 GN=TOM1 PE=1 SV=2"	"5"	"2"	"4"	"2"	"492"	"53.8"	"4.70"	"818.41"	"5.48"	"1"	"2"	"cell organization and biogenesis;other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00790, Pf03127"	"10043"	"ENSG00000100284"	"TOM1"	"B4DEL9; B4DNA1; hsa:10043; O60784; Q5TIJ6; Q86X74"	"Neutrophil degranulation"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"O00469"	"Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 OS=Homo sapiens OX=9606 GN=PLOD2 PE=1 SV=2"	"3"	"2"	"4"	"2"	"737"	"84.6"	"6.71"	"585.14"	"5.48"	"2"	"2"	"protein metabolism;other metabolic processes;stress response"	"other membranes;ER/Golgi"	"other molecular function"	"Pf03171"	"5352"	"ENSG00000152952"	"PLOD2"	"B3KWS3; hsa:5352; O00469; Q59ED2; Q8N170"	"Collagen biosynthesis and modifying enzymes"	"Clear cell renal cell carcinoma pathways; Type I collagen synthesis in the context of osteogenesis imperfecta"	"3"	"0"	"20.8"	"25.5"	"91.1"	"26.5"	"25.1"	"19.5"	"68.9"	"9.4"	"14.8"	"18.6"	"19.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99436"	"Proteasome subunit beta type-7 OS=Homo sapiens OX=9606 GN=PSMB7 PE=1 SV=1"	"11"	"3"	"5"	"3"	"277"	"29.9"	"7.68"	"1024.14"	"5.47"	"3"	"2"	"protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00227, Pf12465"	"5695"	"ENSG00000136930"	"PSMB7"	"B4E0P1; hsa:5695; Q5TBG6; Q96AG8; Q99436; Q9BWA7"	"Neutrophil degranulation; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"63"	"0"	"309.6"	"307.1"	"1033.8"	"295.8"	"209.5"	"168.0"	"950.7"	"262.1"	"276.3"	"261.2"	"273.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4P3"	"Transducin beta-like protein 2 OS=Homo sapiens OX=9606 GN=TBL2 PE=1 SV=1"	"5"	"2"	"4"	"2"	"447"	"49.8"	"9.44"	"772.81"	"5.46"	"2"	"2"	"stress response;signal transduction"	"other membranes;ER/Golgi"	"other molecular function"	"Pf00400"	"26608"	"ENSG00000106638"	"TBL2"	"hsa:26608; Q9UQE2; Q9Y4P3"	""	"7q11.23 copy number variation syndrome"	"1"	"0"	"109.4"	"121.9"	"382.4"	"104.2"	"93.6"	"67.7"	"372.7"	"39.0"	"67.9"	"52.1"	"56.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q4U2R6"	"39S ribosomal protein L51, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL51 PE=1 SV=1"	"23"	"2"	"5"	"2"	"128"	"15.1"	"11.27"	"1046.42"	"5.45"	"2"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf10244"	"51258"	"ENSG00000111639"	"MRPL51"	"hsa:51258; Q4U2R6; Q96Q57; Q9BQ36; Q9P0N7"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"38.2"	"46.5"	"130.6"	"40.2"	"35.6"	"25.3"	"83.0"	"10.1"	"17.6"	"13.2"	"18.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95785"	"Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2"	"1"	"1"	"2"	"1"	"1651"	"178.6"	"6.86"	"589.61"	"5.44"	"1"	"1"	"RNA metabolism OR transcription;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	""	"58525"	"ENSG00000011451"	"WIZ"	"B3KVH1; B7ZM82; hsa:58525; M0QY21; O95785; Q4G0E0; Q6P6B0; Q6ZN24; Q7LDY6; Q7LDZ1; Q96IG5; Q96SQ6; Q9BUR8; Q9NPT1"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P17612"	"cAMP-dependent protein kinase catalytic subunit alpha OS=Homo sapiens OX=9606 GN=PRKACA PE=1 SV=2"	"9"	"3"	"5"	"3"	"351"	"40.6"	"8.79"	"1021.99"	"5.44"	"3"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069"	"5566"	"ENSG00000072062; ENSG00000288516"	"PRKACA"	"hsa:5566; P17612; Q32P54; Q9H2Y0; Q9NRB4; Q9NRH9"	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; FCGR3A-mediated IL10 synthesis; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; MAPK6/MAPK4 signaling; Triglyceride catabolism; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production; Ion homeostasis; Interleukin-3, Interleukin-5 and GM-CSF signaling; RET signaling; VEGFA-VEGFR2 Pathway; Factors involved in megakaryocyte development and platelet production; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Vasopressin regulates renal water homeostasis via Aquaporins; Regulation of MECP2 expression and activity; PKA activation; PKA activation in glucagon signalling; Regulation of glycolysis by fructose 2,6-bisphosphate metabolism; CD209 (DC-SIGN) signaling; Rap1 signalling; HDL assembly; DARPP-32 events; CREB1 phosphorylation through the activation of Adenylate Cyclase; Loss of phosphorylation of MECP2 at T308; ROBO receptors bind AKAP5; PKA-mediated phosphorylation of key metabolic factors"	"Nicotine effect on dopaminergic neurons; Sterol regulatory element-binding proteins (SREBP) signaling; Follicle stimulating hormone (FSH) signaling pathway; Microtubule cytoskeleton regulation; Dopamine metabolism; Common pathways underlying drug addiction; Complement system; Mesodermal commitment pathway; IL-3 signaling pathway; Myometrial relaxation and contraction pathways; Mesodermal commitment pathway; G protein signaling pathways; MAPK signaling pathway; Cannabinoid receptor signaling; Lipid metabolism pathway; Phosphodiesterases in neuronal function; Ras signaling; Hedgehog signaling pathway; Thermogenesis; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Gastrin signaling pathway; Endochondral ossification; Endochondral ossification with skeletal dysplasias; GPR143 in melanocytes and retinal pigment epithelium cells; Neuroinflammation and glutamatergic signaling; GDNF signaling; Urotensin-II-mediated signaling pathway; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways; Estrogen signaling pathway"	"70"	"0"	"322.6"	"231.0"	"915.9"	"253.5"	"206.9"	"178.7"	"904.1"	"93.5"	"138.8"	"107.6"	"95.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60244"	"Mediator of RNA polymerase II transcription subunit 14 OS=Homo sapiens OX=9606 GN=MED14 PE=1 SV=2"	"1"	"2"	"4"	"2"	"1454"	"160.5"	"8.73"	"487.10"	"5.44"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf08638"	"9282"	"ENSG00000180182"	"MED14"	"hsa:9282; O60244; Q4KMR7; Q9UNB3"	"PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; Generic Transcription Pathway"	"Vitamin D in inflammatory diseases"	"4"	"0"	"44.3"	"59.3"	"227.4"	"54.3"	"50.5"	"38.0"	"316.1"	"35.1"	"41.9"	"32.9"	"32.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BUL8"	"Programmed cell death protein 10 OS=Homo sapiens OX=9606 GN=PDCD10 PE=1 SV=1"	"10"	"2"	"4"	"2"	"212"	"24.7"	"8.19"	"750.22"	"5.44"	"2"	"2"	"cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf06840"	"11235"	"ENSG00000114209"	"PDCD10"	"A8K515; D3DNN5; hsa:11235; O14811; Q9BUL8"	""	""	"0"	"0"	"138.3"	"151.5"	"617.2"	"151.8"	"105.5"	"83.2"	"637.2"	"69.5"	"85.4"	"73.8"	"81.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13618"	"Cullin-3 OS=Homo sapiens OX=9606 GN=CUL3 PE=1 SV=2"	"2"	"2"	"4"	"2"	"768"	"88.9"	"8.48"	"606.30"	"5.42"	"2"	"2"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00888, Pf10557"	"8452"	"ENSG00000036257"	"CUL3"	"A8K536; B8ZZC3; hsa:8452; O75415; Q13618; Q569L3; Q9UBI8; Q9UET7"	"Antigen processing: Ubiquitination & Proteasome degradation; Hedgehog 'on' state; Potential therapeutics for SARS; Degradation of DVL; Regulation of RAS by GAPs; Neddylation; KEAP1-NFE2L2 pathway; RHOBTB3 ATPase cycle; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle"	"Hedgehog signaling pathway; NRF2-ARE regulation; 22q11.2 copy number variation syndrome; Head and neck squamous cell carcinoma; 1p36 copy number variation syndrome"	"15"	"0"	"146.2"	"152.7"	"438.2"	"139.9"	"115.0"	"113.1"	"431.5"	"81.4"	"116.9"	"116.1"	"179.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IXQ4"	"GPALPP motifs-containing protein 1 OS=Homo sapiens OX=9606 GN=GPALPP1 PE=1 SV=1"	"6"	"2"	"4"	"2"	"340"	"38.1"	"5.41"	"540.42"	"5.42"	"2"	"2"	""	""	""	"Pf12572"	"55425"	"ENSG00000133114"	"GPALPP1"	"A8K8X8; hsa:55425; Q05BX8; Q05D87; Q5T3Z3; Q5T3Z5; Q8IXQ4; Q9C0F9; Q9H2R0; Q9P0W6"	""	""	"0"	"0"	"119.8"	"106.6"	"274.0"	"119.8"	"125.4"	"116.9"	"437.8"	"106.0"	"189.4"	"149.6"	"139.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9GZZ9"	"Ubiquitin-like modifier-activating enzyme 5 OS=Homo sapiens OX=9606 GN=UBA5 PE=1 SV=1"	"5"	"2"	"4"	"2"	"404"	"44.8"	"4.84"	"547.50"	"5.41"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00899"	"79876"	"ENSG00000081307"	"UBA5"	"A6NJL3; D3DNC8; hsa:79876; Q96ST1; Q9GZZ9"	"Antigen processing: Ubiquitination & Proteasome degradation"	""	"1"	"0"	"51.2"	"56.3"	"173.8"	"53.5"	"75.8"	"52.7"	"210.7"	"41.5"	"62.4"	"63.0"	"55.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07711"	"Cathepsin L1 OS=Homo sapiens OX=9606 GN=CTSL PE=1 SV=2"	"4"	"1"	"4"	"1"	"333"	"37.5"	"5.45"	"619.84"	"5.40"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00112, Pf08246"	"1514"	"ENSG00000135047"	"CTSL"	"hsa:1514; P07711; Q6IAV1; Q96QJ0"	"MHC class II antigen presentation; Collagen degradation; Assembly of collagen fibrils and other multimeric structures; Attachment and Entry; RUNX1 regulates transcription of genes involved in differentiation of keratinocytes; Attachment and Entry; Trafficking and processing of endosomal TLR; Endosomal/Vacuolar pathway"	"Primary focal segmental glomerulosclerosis (FSGS); Ebola virus infection in host; Mitochondrial immune response to SARS-CoV-2"	"12"	"0"	"26.0"	"26.8"	"90.9"	"33.4"	"32.8"	"23.7"	"117.4"	"25.5"	"60.0"	"146.8"	"283.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95182"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 OS=Homo sapiens OX=9606 GN=NDUFA7 PE=1 SV=3"	"16"	"1"	"2"	"1"	"113"	"12.5"	"10.18"	"774.99"	"5.40"	"1"	"1"	"protein metabolism;other metabolic processes;transport"	"other membranes;mitochondrion;translational apparatus"	"transporter activity;other molecular function"	"Pf07347"	"4701"	"ENSG00000267855"	"NDUFA7"	"hsa:4701; O95182"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"5"	"0"	"59.0"	"56.3"	"209.9"	"52.2"	"43.4"	"29.1"	"240.0"	"29.5"	"41.7"	"31.3"	"29.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BXF6"	"Rab11 family-interacting protein 5 OS=Homo sapiens OX=9606 GN=RAB11FIP5 PE=1 SV=1"	"6"	"2"	"3"	"2"	"653"	"70.4"	"9.23"	"418.56"	"5.40"	"1"	"2"	"cell-cell signaling;transport;other biological processes"	"other membranes;cytoskeleton;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00168, Pf09457"	"26056"	"ENSG00000135631"	"RAB11FIP5"	"hsa:26056; O94939; Q9BXF6; Q9P0M1"	""	""	"0"	"0"	"18.5"	"15.1"	"45.7"	"20.9"	"20.0"	"14.1"	"61.2"	"26.8"	"46.7"	"53.3"	"75.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q53H96"	"Pyrroline-5-carboxylate reductase 3 OS=Homo sapiens OX=9606 GN=PYCR3 PE=1 SV=3"	"9"	"2"	"4"	"2"	"274"	"28.6"	"7.72"	"519.95"	"5.39"	"2"	"2"	"other metabolic processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf03807, Pf14748"	"65263"	"ENSG00000104524; ENSG00000276657"	"PYCR3"	"B3KMB5; B4DVT6; H0Y6C3; hsa:65263; Q53H96; Q8N3N9; Q96HX4; Q9H896"	"Glutamate and glutamine metabolism"	""	"1"	"0"	"8.9"	"9.0"	"40.4"	"6.1"	"8.6"	"5.4"	"34.3"	"3.4"	"4.0"	"4.5"	"3.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P56556"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 OS=Homo sapiens OX=9606 GN=NDUFA6 PE=1 SV=4"	"14"	"2"	"4"	"2"	"128"	"15.1"	"9.98"	"828.21"	"5.39"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;stress response;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf05347"	"4700"	"ENSG00000184983; ENSG00000272765; ENSG00000273397; ENSG00000277365; ENSG00000281013"	"NDUFA6"	"B2RE54; hsa:4700; O43675; P56556; Q6FGW0; Q6IBT8; Q6IC39"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"5"	"0"	"182.3"	"222.1"	"915.8"	"195.7"	"175.2"	"144.1"	"776.8"	"63.2"	"115.8"	"92.7"	"90.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55327"	"Tumor protein D52 OS=Homo sapiens OX=9606 GN=TPD52 PE=1 SV=2"	"13"	"2"	"4"	"2"	"224"	"24.3"	"4.83"	"541.20"	"5.38"	"2"	"2"	"transport;other biological processes"	"ER/Golgi;other cell component"	"other molecular function"	"Pf04201"	"7163"	"ENSG00000076554"	"TPD52"	"B7Z414; C9J502; D0UFD1; D0UFD2; D0UFD3; D0UFD4; D0UFD5; E5RKB4; hsa:7163; P55327; Q13056; Q53EK8; Q6FGP3; Q6FGS3; Q86YZ2; Q9UCX8"	"Golgi Associated Vesicle Biogenesis"	""	"1"	"0"	"7.4"	"2.4"	"56.4"	"8.2"	"1.6"	"0.0"	"46.2"	"0.0"	"0.8"	"0.0"	"0.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2Q9"	"28S ribosomal protein S28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS28 PE=1 SV=1"	"10"	"2"	"4"	"2"	"187"	"20.8"	"9.10"	"703.95"	"5.38"	"2"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	""	"Pf10246"	"28957"	"ENSG00000147586"	"MRPS28"	"B2RDZ7; hsa:28957; Q96Q21; Q9Y2Q9"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"349.9"	"293.9"	"988.8"	"290.1"	"259.7"	"218.3"	"1038.6"	"136.1"	"171.9"	"127.3"	"128.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15437"	"Protein transport protein Sec23B OS=Homo sapiens OX=9606 GN=SEC23B PE=1 SV=2"	"2"	"1"	"5"	"1"	"767"	"86.4"	"6.89"	"923.42"	"5.37"	"1"	"1"	"cell organization and biogenesis;transport"	"other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00626, Pf04810, Pf04811, Pf04815, Pf08033"	"10483"	"ENSG00000101310"	"SEC23B"	"D3DW33; hsa:10483; Q15437; Q503A9; Q5W183; Q9BS15; Q9BSI2; Q9H1D7"	""	"Sterol regulatory element-binding proteins (SREBP) signaling"	"1"	"0"	"9.5"	"9.9"	"35.6"	"6.1"	"12.8"	"9.7"	"21.9"	"6.1"	"5.1"	"4.7"	"5.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95817"	"BAG family molecular chaperone regulator 3 OS=Homo sapiens OX=9606 GN=BAG3 PE=1 SV=3"	"4"	"2"	"3"	"2"	"575"	"61.6"	"6.95"	"380.31"	"5.36"	"1"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00397, Pf02179"	"9531"	"ENSG00000151929"	"BAG3"	"A8K5L8; hsa:9531; O95817; Q3B763; Q9NT20; Q9P120"	"Regulation of HSF1-mediated heat shock response"	"Cell interactions of the pancreatic cancer microenvironment"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07203"	"Glutathione peroxidase 1 OS=Homo sapiens OX=9606 GN=GPX1 PE=1 SV=4"	"19"	"2"	"2"	"2"	"203"	"22.1"	"6.55"	""	"5.35"	""	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00255"	"2876"	"ENSG00000233276"	"GPX1"	"E9PAS1; hsa:2876; P07203; Q7Z5H1; Q9BW12"	"Detoxification of Reactive Oxygen Species; Synthesis of 15-eicosatetraenoic acid derivatives; Synthesis of 12-eicosatetraenoic acid derivatives; Synthesis of 5-eicosatetraenoic acids"	"Glutathione metabolism; Selenium micronutrient network; Folate metabolism; Amyotrophic lateral sclerosis (ALS); Trans-sulfuration, one-carbon metabolism and related pathways; Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; TYROBP causal network in microglia; Oxidative stress response; Male infertility; p53 transcriptional gene network"	"15"	"0"	"30.0"	"24.8"	"84.7"	"34.2"	"27.8"	"22.7"	"99.1"	"13.1"	"22.2"	"15.1"	"17.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NWW5"	"Ceroid-lipofuscinosis neuronal protein 6 OS=Homo sapiens OX=9606 GN=CLN6 PE=1 SV=1"	"7"	"1"	"1"	"1"	"311"	"35.9"	"8.87"	""	"5.35"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"other membranes;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf15156"	"54982"	"ENSG00000128973"	"CLN6"	"A8K560; B4DDH6; hsa:54982; Q6IAB1; Q96SR0; Q9NWW5"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9NP79"	"Vacuolar protein sorting-associated protein VTA1 homolog OS=Homo sapiens OX=9606 GN=VTA1 PE=1 SV=1"	"9"	"2"	"3"	"2"	"307"	"33.9"	"6.29"	"804.59"	"5.35"	"2"	"1"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	""	"Pf04652, Pf18097"	"51534"	"ENSG00000009844"	"VTA1"	"B4DW55; E1P594; E7ETQ7; hsa:51534; Q5TGM1; Q6IAE8; Q9H0R2; Q9H3K9; Q9NP79; Q9P0Q0"	"Budding and maturation of HIV virion; Endosomal Sorting Complex Required For Transport (ESCRT)"	""	"2"	"0"	"162.5"	"176.6"	"550.8"	"164.9"	"145.4"	"121.4"	"667.6"	"91.7"	"116.2"	"98.6"	"96.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95163"	"Elongator complex protein 1 OS=Homo sapiens OX=9606 GN=ELP1 PE=1 SV=3"	"2"	"2"	"4"	"2"	"1332"	"150.2"	"5.94"	"589.29"	"5.35"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04762"	"8518"	"ENSG00000070061"	"ELP1"	"hsa:8518; O95163; Q5JSV2; Q9H327; Q9UG87"	"HATs acetylate histones"	""	"1"	"0"	"35.8"	"42.7"	"111.9"	"41.9"	"38.0"	"34.1"	"89.5"	"17.7"	"27.4"	"21.3"	"22.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N163"	"Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2"	"3"	"3"	"4"	"3"	"923"	"102.8"	"5.22"	"622.76"	"5.35"	"2"	"2"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytoskeleton;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf14443, Pf14444, Pf19256, Pf19257"	"57805"	"ENSG00000158941"	"CCAR2"	"A6NL03; B2RB79; D3DSR6; hsa:57805; Q6P0Q9; Q8N163; Q8N3G7; Q8N8M1; Q8TF34; Q9H9Q9; Q9HD12; Q9NT55"	"Regulation of HSF1-mediated heat shock response"	""	"1"	"0"	"258.1"	"322.5"	"839.5"	"331.5"	"287.5"	"266.9"	"836.4"	"139.4"	"190.2"	"176.5"	"171.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UL25"	"Ras-related protein Rab-21 OS=Homo sapiens OX=9606 GN=RAB21 PE=1 SV=3"	"10"	"2"	"4"	"2"	"225"	"24.3"	"7.94"	"712.14"	"5.34"	"2"	"2"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00071"	"23011"	"ENSG00000080371"	"RAB21"	"hsa:23011; Q14466; Q569H3; Q9UL25"	"RAB GEFs exchange GTP for GDP on RABs; RAB geranylgeranylation"	"Ciliary landscape"	"3"	"0"	"30.8"	"35.6"	"197.0"	"41.0"	"29.9"	"15.3"	"189.3"	"28.6"	"28.5"	"18.4"	"18.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6NUK1"	"Calcium-binding mitochondrial carrier protein SCaMC-1 OS=Homo sapiens OX=9606 GN=SLC25A24 PE=1 SV=2"	"4"	"2"	"4"	"2"	"477"	"53.3"	"6.33"	"631.67"	"5.32"	"2"	"2"	"stress response;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00153, Pf13499"	"29957"	"ENSG00000085491; ENSG00000284468"	"SLC25A24"	"B7ZAI9; hsa:29957; Q5T331; Q5T485; Q6NUK1; Q6PJJ9; Q705K4; Q9P129"	""	""	"0"	"0"	"209.5"	"229.0"	"937.0"	"220.0"	"175.2"	"125.5"	"860.5"	"73.1"	"132.8"	"124.4"	"138.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92620"	"Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 OS=Homo sapiens OX=9606 GN=DHX38 PE=1 SV=2"	"2"	"2"	"4"	"2"	"1227"	"140.4"	"6.54"	"585.39"	"5.32"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"9785"	"ENSG00000140829"	"DHX38"	"B4DVG8; D3DWS7; hsa:9785; O75212; Q92620; Q96HN7"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"mRNA processing"	"5"	"0"	"12.9"	"12.4"	"51.6"	"14.6"	"13.0"	"13.6"	"43.2"	"7.7"	"11.3"	"9.3"	"12.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60306"	"RNA helicase aquarius OS=Homo sapiens OX=9606 GN=AQR PE=1 SV=4"	"1"	"2"	"4"	"2"	"1485"	"171.2"	"6.37"	"604.13"	"5.32"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf13086, Pf13087, Pf16399"	"9716"	"ENSG00000021776"	"AQR"	"A0JP17; A5YKK3; hsa:9716; O60306; Q2YDX9; Q6IRU8; Q6PIC8"	"mRNA Splicing - Major Pathway; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	""	"5"	"0"	"11.8"	"27.6"	"62.0"	"19.5"	"26.1"	"16.9"	"46.0"	"10.8"	"8.7"	"8.0"	"15.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HAS0"	"Protein Njmu-R1 OS=Homo sapiens OX=9606 GN=C17orf75 PE=1 SV=2"	"3"	"1"	"4"	"1"	"396"	"44.6"	"5.03"	"548.71"	"5.31"	"1"	"1"	"cell organization and biogenesis;transport"	"ER/Golgi;other cell component"	""	"Pf15053"	"64149"	"ENSG00000108666"	"C17orf75"	"hsa:64149; Q7Z2H4; Q9HAS0"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05089"	"Arginase-1 OS=Homo sapiens OX=9606 GN=ARG1 PE=1 SV=2"	"10"	"2"	"3"	"2"	"322"	"34.7"	"7.21"	"431.26"	"5.31"	"1"	"2"	"other metabolic processes;stress response;developmental processes;other biological processes"	"non-structural extracellular;other membranes;cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00491"	"383"	"ENSG00000118520"	"ARG1"	"A6NEA0; hsa:383; P05089; Q5JWT5; Q5JWT6; Q8TE72; Q9BS50"	"Neutrophil degranulation; Urea cycle"	"Spinal cord injury; Amino acid metabolism; IL-18 signaling pathway"	"5"	"0"	"45.4"	"21.3"	"22.1"	"11.0"	"9.0"	"1.6"	"20.2"	"6.1"	"2.1"	"4.1"	"3.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P26196"	"Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2"	"7"	"4"	"5"	"4"	"483"	"54.4"	"8.66"	"1364.06"	"5.31"	"4"	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"1656"	"ENSG00000110367"	"DDX6"	"hsa:1656; P26196; Q5D048"	"mRNA decay by 5' to 3' exoribonuclease"	""	"1"	"0"	"377.7"	"411.2"	"1430.1"	"396.8"	"264.7"	"219.8"	"1401.5"	"125.0"	"193.9"	"161.4"	"180.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P41240"	"Tyrosine-protein kinase CSK OS=Homo sapiens OX=9606 GN=CSK PE=1 SV=1"	"5"	"2"	"4"	"2"	"450"	"50.7"	"7.06"	"567.22"	"5.30"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00017, Pf00018, Pf07714"	"1445"	"ENSG00000103653"	"CSK"	"hsa:1445; P41240; Q2M3N2; Q6FGZ6"	"Signaling by BRAF and RAF1 fusions; GAB1 signalosome; Integrin signaling; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; Phosphorylation of CD3 and TCR zeta chains; PD-1 signaling; Negative regulation of FLT3; RHOH GTPase cycle"	"Integrin-mediated cell adhesion; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; EGF/EGFR signaling pathway; Regulation of actin cytoskeleton"	"18"	"0"	"13.6"	"10.8"	"51.8"	"12.9"	"9.5"	"8.9"	"68.1"	"3.7"	"7.8"	"4.7"	"2.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IXM3"	"39S ribosomal protein L41, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL41 PE=1 SV=1"	"12"	"2"	"3"	"2"	"137"	"15.4"	"9.57"	"344.92"	"5.30"	"1"	"2"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus;other cell component"	"other molecular function"	"Pf09809"	"64975"	"ENSG00000182154"	"MRPL41"	"hsa:64975; Q8IXM3; Q96Q49"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"203.0"	"245.1"	"632.7"	"196.8"	"188.9"	"168.9"	"759.8"	"139.3"	"163.9"	"139.9"	"172.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TAT6"	"Nuclear protein localization protein 4 homolog OS=Homo sapiens OX=9606 GN=NPLOC4 PE=1 SV=3"	"3"	"1"	"2"	"1"	"608"	"68.1"	"6.38"	"552.28"	"5.30"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf05020, Pf05021, Pf11543"	"55666"	"ENSG00000182446"	"NPLOC4"	"hsa:55666; Q8N3J1; Q8TAT6; Q9H8V2; Q9H964; Q9NWR5; Q9P229"	"Neddylation; KEAP1-NFE2L2 pathway; Translesion Synthesis by POLH"	""	"3"	"0"	"89.6"	"108.5"	"247.3"	"104.0"	"104.1"	"98.5"	"256.9"	"63.9"	"92.6"	"72.3"	"72.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NX20"	"39S ribosomal protein L16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL16 PE=1 SV=1"	"8"	"2"	"4"	"2"	"251"	"28.4"	"10.13"	"589.89"	"5.29"	"2"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00252"	"54948"	"ENSG00000166902"	"MRPL16"	"hsa:54948; Q9BYD0; Q9HB70; Q9NX20"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"172.0"	"185.1"	"500.1"	"166.5"	"179.6"	"152.1"	"487.3"	"74.2"	"115.1"	"107.1"	"117.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P40616"	"ADP-ribosylation factor-like protein 1 OS=Homo sapiens OX=9606 GN=ARL1 PE=1 SV=1"	"15"	"2"	"4"	"2"	"181"	"20.4"	"5.72"	"891.66"	"5.28"	"1"	"2"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00025"	"400"	"ENSG00000120805"	"ARL1"	"B4DWW1; hsa:400; P40616; P80417; Q53XB1"	"Retrograde transport at the Trans-Golgi-Network"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NXH9"	"tRNA (guanine(26)-N(2))-dimethyltransferase OS=Homo sapiens OX=9606 GN=TRMT1 PE=1 SV=1"	"3"	"2"	"3"	"2"	"659"	"72.2"	"7.64"	"272.04"	"5.27"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00642, Pf02005"	"55621"	"ENSG00000104907"	"TRMT1"	"hsa:55621; O76103; Q548Y5; Q8WVA6; Q9NXH9"	"tRNA modification in the nucleus and cytosol"	""	"1"	"0"	"30.8"	"31.4"	"158.1"	"35.9"	"26.3"	"19.0"	"218.1"	"15.4"	"25.1"	"25.2"	"20.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EY8"	"Corrinoid adenosyltransferase OS=Homo sapiens OX=9606 GN=MMAB PE=1 SV=1"	"8"	"2"	"3"	"2"	"250"	"27.4"	"8.60"	"357.11"	"5.27"	"1"	"2"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf01923"	"326625"	"ENSG00000139428"	"MMAB"	"C5HU05; hsa:326625; Q96EY8; Q9BSH0"	"Cobalamin (Cbl) metabolism; Defective MMAB causes MMA, cblB type"	"Vitamin B12 metabolism"	"3"	"0"	"123.4"	"120.9"	"463.8"	"116.7"	"104.2"	"80.1"	"509.1"	"67.8"	"83.3"	"70.3"	"82.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12765"	"Secernin-1 OS=Homo sapiens OX=9606 GN=SCRN1 PE=1 SV=2"	"3"	"1"	"2"	"1"	"414"	"46.4"	"4.75"	"602.85"	"5.26"	"1"	"1"	"protein metabolism;transport;other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf03577"	"9805"	"ENSG00000136193"	"SCRN1"	"A8K0E9; B4DHM0; B4DIP5; C9JPG0; hsa:9805; Q12765; Q25QX7; Q8IWD1"	""	""	"0"	"0"	"127.1"	"151.0"	"742.2"	"148.7"	"154.7"	"80.6"	"1147.8"	"83.4"	"141.8"	"59.7"	"38.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46821"	"Microtubule-associated protein 1B OS=Homo sapiens OX=9606 GN=MAP1B PE=1 SV=2"	"1"	"3"	"4"	"3"	"2468"	"270.5"	"4.81"	"716.98"	"5.26"	"2"	"2"	"cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00414"	"4131"	"ENSG00000131711"	"MAP1B"	"A2BDK5; hsa:4131; P46821"	""	"Microtubule cytoskeleton regulation; Fragile X syndrome; Neurogenesis regulation in the olfactory epithelium"	"3"	"0"	"65.1"	"68.0"	"237.6"	"73.1"	"72.1"	"64.8"	"266.7"	"40.1"	"61.2"	"57.3"	"55.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z478"	"ATP-dependent RNA helicase DHX29 OS=Homo sapiens OX=9606 GN=DHX29 PE=1 SV=2"	"2"	"3"	"5"	"3"	"1369"	"155.1"	"8.09"	"855.73"	"5.25"	"3"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"54505"	"ENSG00000067248"	"DHX29"	"hsa:54505; O75549; Q63HN0; Q63HN3; Q7Z478; Q8IWW2; Q8N3A1; Q9UMH2"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"30.0"	"27.6"	"81.3"	"26.7"	"23.2"	"19.3"	"87.7"	"11.1"	"11.7"	"8.2"	"13.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13330"	"Metastasis-associated protein MTA1 OS=Homo sapiens OX=9606 GN=MTA1 PE=1 SV=2"	"5"	"3"	"5"	"3"	"715"	"80.7"	"9.26"	"928.83"	"5.24"	"3"	"2"	"cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00249, Pf00320, Pf01426, Pf01448, Pf17226"	"9112"	"ENSG00000182979"	"MTA1"	"A5PLK4; hsa:9112; Q13330; Q86SW2; Q8NFI8; Q96GI8"	"Potential therapeutics for SARS; Regulation of PTEN gene transcription; HDACs deacetylate histones; RNA Polymerase I Transcription Initiation; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; SUMOylation of transcription factors"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"7"	"0"	"28.9"	"26.9"	"110.2"	"26.8"	"16.5"	"18.1"	"125.2"	"12.5"	"16.5"	"15.3"	"13.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75165"	"DnaJ homolog subfamily C member 13 OS=Homo sapiens OX=9606 GN=DNAJC13 PE=1 SV=5"	"1"	"2"	"3"	"2"	"2243"	"254.3"	"6.74"	"372.72"	"5.24"	"1"	"2"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	""	"Pf00226, Pf14237, Pf19432"	"23317"	"ENSG00000138246"	"DNAJC13"	"hsa:23317; O75165; Q3L0T1; Q6PI82; Q6UJ77; Q6ZSW1; Q6ZUT5; Q86XG3; Q96DC1; Q9BWK9"	"Neutrophil degranulation"	""	"1"	"0"	"36.4"	"31.1"	"94.6"	"32.6"	"25.8"	"17.4"	"118.6"	"22.6"	"28.5"	"31.7"	"24.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55084"	"Trifunctional enzyme subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=HADHB PE=1 SV=3"	"7"	"4"	"6"	"3"	"474"	"51.3"	"9.41"	"1208.02"	"5.23"	"4"	"2"	"other metabolic processes;other biological processes"	"other membranes;mitochondrion;ER/Golgi"	"nucleic acid binding activity;other molecular function"	"Pf00108, Pf02803"	"3032"	"ENSG00000138029"	"HADHB"	"B2RB16; B4E2W0; hsa:3032; O14969; P55084; Q53TA6; Q96C77; Q9H3F5; Q9T2V8"	"Acyl chain remodeling of CL; mitochondrial fatty acid beta-oxidation of unsaturated fatty acids; Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA; Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of myristoyl-CoA to lauroyl-CoA; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA; Beta oxidation of palmitoyl-CoA to myristoyl-CoA"	"Fatty acid beta-oxidation; Valproic acid pathway; Female steroid hormones in cardiomyocyte energy metabolism; Sudden infant death syndrome (SIDS) susceptibility pathways"	"12"	"1"	"301.6"	"327.5"	"1180.5"	"274.2"	"260.7"	"183.1"	"1205.7"	"96.5"	"150.9"	"112.4"	"127.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UDR5"	"Alpha-aminoadipic semialdehyde synthase, mitochondrial OS=Homo sapiens OX=9606 GN=AASS PE=1 SV=1"	"2"	"1"	"2"	"1"	"926"	"102.1"	"6.64"	"613.57"	"5.23"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01262, Pf03435, Pf05222, Pf16653"	"10157"	"ENSG00000008311"	"AASS"	"hsa:10157; O95462; Q9UDR5"	"Lysine catabolism"	""	"1"	"0"	"42.8"	"42.9"	"193.6"	"45.0"	"39.7"	"31.3"	"209.1"	"24.7"	"33.5"	"23.5"	"26.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16555"	"Dihydropyrimidinase-related protein 2 OS=Homo sapiens OX=9606 GN=DPYSL2 PE=1 SV=1"	"6"	"3"	"4"	"2"	"572"	"62.3"	"6.38"	"574.78"	"5.23"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton"	"other molecular function"	"Pf01979"	"1808"	"ENSG00000092964"	"DPYSL2"	"A8K5H2; B4DR31; D3DSS7; hsa:1808; O00424; Q16555"	"CRMPs in Sema3A signaling; Recycling pathway of L1"	"Microtubule cytoskeleton regulation; Brain-derived neurotrophic factor (BDNF) signaling pathway"	"4"	"1"	"39.9"	"52.6"	"204.6"	"39.3"	"26.5"	"16.8"	"297.1"	"27.8"	"28.0"	"25.2"	"22.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43432"	"Eukaryotic translation initiation factor 4 gamma 3 OS=Homo sapiens OX=9606 GN=EIF4G3 PE=1 SV=2"	"3"	"4"	"6"	"2"	"1585"	"176.5"	"5.38"	"1241.34"	"5.22"	"4"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf02020, Pf02847, Pf02854"	"8672"	"ENSG00000075151"	"EIF4G3"	"B9EGQ7; hsa:8672; O43432; Q15597; Q504Z1; Q5SWC3; Q8NEN1"	"ISG15 antiviral mechanism"	"Translation factors; Translation inhibitors in chronically activated PDGFRA cells"	"3"	"0"	"12.1"	"16.9"	"67.0"	"10.1"	"12.9"	"8.9"	"57.6"	"9.0"	"8.3"	"8.0"	"9.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NC60"	"Nitric oxide-associated protein 1 OS=Homo sapiens OX=9606 GN=NOA1 PE=1 SV=2"	"3"	"2"	"4"	"2"	"698"	"78.4"	"8.66"	"609.07"	"5.21"	"2"	"2"	"cell organization and biogenesis;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf01926"	"84273"	"ENSG00000084092"	"NOA1"	"hsa:84273; Q8N7L6; Q8NC60; Q9BSQ9"	""	""	"0"	"0"	"8.1"	"11.3"	"28.8"	"8.9"	"9.9"	"4.1"	"23.7"	"2.9"	"6.7"	"9.5"	"5.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HCE1"	"Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2"	"4"	"3"	"5"	"3"	"1003"	"113.6"	"8.82"	"912.24"	"5.21"	"3"	"2"	"stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13087, Pf13604"	"4343"	"ENSG00000155363"	"MOV10"	"hsa:4343; Q5JR03; Q8TEF0; Q9BSY3; Q9BUJ9; Q9HCE1"	"MAPK6/MAPK4 signaling; Oxidative Stress Induced Senescence; Estrogen-dependent gene expression; Pre-NOTCH Transcription and Translation; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Regulation of MECP2 expression and activity; TP53 Regulates Metabolic Genes; Oncogene Induced Senescence; Transcriptional Regulation by VENTX; Ca2+ pathway; NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux; Regulation of RUNX1 Expression and Activity; Regulation of CDH11 mRNA translation by microRNAs; Regulation of NPAS4 mRNA translation; Competing endogenous RNAs (ceRNAs) regulate PTEN translation"	"VEGFA-VEGFR2 signaling"	"18"	"0"	"118.9"	"104.2"	"454.9"	"128.1"	"99.4"	"84.2"	"488.7"	"66.2"	"91.8"	"71.7"	"81.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35270"	"Sepiapterin reductase OS=Homo sapiens OX=9606 GN=SPR PE=1 SV=1"	"10"	"3"	"5"	"3"	"261"	"28.0"	"8.05"	"904.70"	"5.21"	"3"	"2"	"other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf00106"	"6697"	"ENSG00000116096"	"SPR"	"A8K741; D6W5H2; hsa:6697; P35270; Q53GI9; Q9UBB1"	"eNOS activation; Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"	""	"2"	"0"	"266.8"	"250.7"	"701.6"	"265.1"	"263.2"	"262.1"	"756.1"	"133.0"	"256.1"	"156.7"	"184.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96A26"	"Protein FAM162A OS=Homo sapiens OX=9606 GN=FAM162A PE=1 SV=2"	"23"	"3"	"4"	"3"	"154"	"17.3"	"9.77"	"596.71"	"5.18"	"2"	"2"	"stress response;other biological processes"	"other membranes;cytosol;mitochondrion"	""	"Pf06388"	"26355"	"ENSG00000114023"	"FAM162A"	"hsa:26355; Q96A26; Q9NRN6; Q9UJX8"	""	""	"0"	"0"	"169.5"	"196.0"	"886.4"	"173.9"	"156.9"	"95.9"	"1307.5"	"89.2"	"138.3"	"100.6"	"88.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86UV5"	"Ubiquitin carboxyl-terminal hydrolase 48 OS=Homo sapiens OX=9606 GN=USP48 PE=1 SV=1"	"2"	"2"	"4"	"2"	"1035"	"119.0"	"6.05"	"688.39"	"5.17"	"2"	"2"	"protein metabolism;other metabolic processes"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf00443"	"84196"	"ENSG00000090686"	"USP48"	"B7ZKS7; hsa:84196; Q2M3I4; Q5SZI4; Q5T3T5; Q6NX53; Q86UV5; Q8N3F6; Q96F64; Q96IQ3; Q9H5N3; Q9H5T7; Q9NUJ6; Q9NXR0"	"Ub-specific processing proteases"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3B7"	"39S ribosomal protein L11, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL11 PE=1 SV=1"	"8"	"2"	"3"	"2"	"192"	"20.7"	"9.91"	"369.50"	"5.17"	"1"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00298, Pf03946"	"65003"	"ENSG00000174547"	"MRPL11"	"A6NLT0; A8K219; hsa:65003; Q32P46; Q96Q73; Q9Y3B7"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"453.3"	"510.0"	"1488.2"	"435.2"	"381.1"	"350.5"	"1405.8"	"172.5"	"284.2"	"232.9"	"284.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86VM9"	"Zinc finger CCCH domain-containing protein 18 OS=Homo sapiens OX=9606 GN=ZC3H18 PE=1 SV=2"	"2"	"3"	"5"	"3"	"953"	"106.3"	"8.32"	"821.19"	"5.17"	"3"	"2"	"other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf18044"	"124245"	"ENSG00000158545"	"ZC3H18"	"hsa:124245; Q86VM9; Q96DG4; Q96MP7"	""	""	"0"	"0"	"105.2"	"105.5"	"351.0"	"128.1"	"122.6"	"110.1"	"1048.9"	"440.9"	"704.4"	"620.7"	"656.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00411"	"DNA-directed RNA polymerase, mitochondrial OS=Homo sapiens OX=9606 GN=POLRMT PE=1 SV=2"	"3"	"3"	"5"	"3"	"1230"	"138.5"	"8.98"	"775.48"	"5.17"	"3"	"2"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00940, Pf14700"	"5442"	"ENSG00000099821"	"POLRMT"	"hsa:5442; O00411; O60370"	"Mitochondrial transcription initiation; Transcriptional activation of mitochondrial biogenesis"	"Mitochondrial gene expression"	"3"	"0"	"96.7"	"141.5"	"409.8"	"140.1"	"130.8"	"119.5"	"401.4"	"53.7"	"100.8"	"72.3"	"74.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13423"	"NAD(P) transhydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=NNT PE=1 SV=3"	"2"	"2"	"4"	"2"	"1086"	"113.8"	"8.09"	"621.00"	"5.15"	"2"	"2"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf01262, Pf02233, Pf05222, Pf12769"	"23530"	"ENSG00000112992"	"NNT"	"hsa:23530; Q13423; Q16796; Q2TB60; Q8N3V4"	"Citric acid cycle (TCA cycle)"	""	"1"	"0"	"173.8"	"168.2"	"574.2"	"146.4"	"140.6"	"112.8"	"582.8"	"88.9"	"145.9"	"113.6"	"108.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43395"	"U4/U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2"	"3"	"2"	"3"	"2"	"683"	"77.5"	"9.50"	"381.71"	"5.15"	"1"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf01480, Pf06544, Pf08572"	"9129"	"ENSG00000117360"	"PRPF3"	"B4DSY9; hsa:9129; O43395; O43446; Q5VT54"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"0"	"26.6"	"28.6"	"89.0"	"26.9"	"18.8"	"22.8"	"79.7"	"6.6"	"20.5"	"22.7"	"18.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EY1"	"DnaJ homolog subfamily A member 3, mitochondrial OS=Homo sapiens OX=9606 GN=DNAJA3 PE=1 SV=2"	"5"	"1"	"1"	"1"	"480"	"52.5"	"9.26"	""	"5.15"	""	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00226, Pf00684, Pf01556"	"9093"	"ENSG00000103423; ENSG00000276726"	"DNAJA3"	"B2RAJ5; B4DI33; E7ES32; hsa:9093; O75472; Q8WUJ6; Q8WXJ3; Q96D76; Q96EY1; Q96IV1; Q9NYH8"	""	""	"0"	"0"	"10.9"	"10.5"	"30.0"	"6.7"	"12.0"	"10.4"	"31.0"	"5.4"	"7.6"	"4.8"	"3.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKA9"	"Polypyrimidine tract-binding protein 2 OS=Homo sapiens OX=9606 GN=PTBP2 PE=1 SV=1"	"3"	"2"	"5"	"1"	"531"	"57.5"	"8.66"	"1036.17"	"5.14"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf11835, Pf13893"	"58155"	"ENSG00000117569"	"PTBP2"	"hsa:58155; Q8N0Z1; Q8N160; Q8NFB0; Q8NFB1; Q969N9; Q96Q76; Q9UKA9"	""	"Genes targeted by miRNAs in adipocytes; mRNA processing"	"2"	"0"	"117.6"	"110.7"	"360.2"	"80.3"	"100.1"	"76.2"	"400.4"	"59.4"	"80.0"	"79.9"	"87.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99661"	"Kinesin-like protein KIF2C OS=Homo sapiens OX=9606 GN=KIF2C PE=1 SV=2"	"3"	"2"	"4"	"2"	"725"	"81.3"	"7.83"	"677.14"	"5.14"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00225"	"11004"	"ENSG00000142945"	"KIF2C"	"B3ITR9; hsa:11004; Q5JR88; Q6ICU1; Q96C18; Q96HB8; Q99661; Q9BWV8"	"Separation of Sister Chromatids; COPI-dependent Golgi-to-ER retrograde traffic; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Kinesins; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"Microtubule cytoskeleton regulation"	"10"	"0"	"42.1"	"37.4"	"132.0"	"35.4"	"26.5"	"27.2"	"125.7"	"11.5"	"18.9"	"20.1"	"17.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5V0"	"Zinc finger protein 706 OS=Homo sapiens OX=9606 GN=ZNF706 PE=1 SV=1"	"24"	"2"	"3"	"2"	"76"	"8.5"	"10.01"	"239.75"	"5.11"	"1"	"2"	"other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf04419, Pf12874"	"51123"	"ENSG00000120963"	"ZNF706"	"A8K362; hsa:51123; Q9Y5V0"	"Generic Transcription Pathway"	""	"1"	"0"	"239.8"	"219.0"	"431.0"	"229.0"	"239.4"	"234.9"	"1011.9"	"357.7"	"758.0"	"719.7"	"943.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15643"	"Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3"	"1"	"2"	"4"	"1"	"1979"	"227.4"	"5.26"	"502.28"	"5.11"	"2"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes"	"other membranes;cytoskeleton;ER/Golgi"	"other molecular function"	""	"9321"	"ENSG00000100815"	"TRIP11"	"B2RUT2; hsa:9321; O14689; O15154; O95949; Q15643; Q6MZL5"	"Intraflagellar transport; Intra-Golgi traffic; Signaling by FLT3 fusion proteins"	""	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P78344"	"Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1"	"3"	"2"	"3"	"2"	"907"	"102.3"	"7.14"	"269.73"	"5.09"	"1"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus"	"nucleic acid binding activity"	"Pf02020, Pf02847, Pf02854"	"1982"	"ENSG00000110321"	"EIF4G2"	"hsa:1982; O60877; P78344; P78404; Q0VH00; Q0VH01; Q2NKW9; Q49A79; Q53EU1; Q58EZ2; Q8NI71; Q96C16"	"ISG15 antiviral mechanism"	"VEGFA-VEGFR2 signaling; Exercise-induced circadian regulation; Acute viral myocarditis"	"4"	"0"	"16.2"	"17.1"	"61.3"	"14.5"	"17.6"	"13.4"	"51.6"	"12.0"	"16.6"	"17.6"	"18.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46926"	"Glucosamine-6-phosphate isomerase 1 OS=Homo sapiens OX=9606 GN=GNPDA1 PE=1 SV=1"	"7"	"2"	"3"	"2"	"289"	"32.6"	"6.92"	"339.90"	"5.09"	"1"	"2"	"other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf01182"	"10007"	"ENSG00000113552"	"GNPDA1"	"B7Z3X4; D3DQE7; hsa:10007; P46926"	"Glycolysis"	"11p11.2 copy number variation syndrome"	"2"	"0"	"111.6"	"109.7"	"390.9"	"110.3"	"106.1"	"72.7"	"528.0"	"64.5"	"91.8"	"74.4"	"83.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94832"	"Unconventional myosin-Id OS=Homo sapiens OX=9606 GN=MYO1D PE=1 SV=2"	"2"	"2"	"3"	"2"	"1006"	"116.1"	"9.39"	"305.43"	"5.08"	"1"	"2"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00063, Pf00612, Pf06017"	"4642"	"ENSG00000176658"	"MYO1D"	"A6H8V3; hsa:4642; O94832; Q8NHP9"	""	""	"0"	"0"	"9.3"	"12.3"	"43.2"	"7.5"	"7.4"	"4.0"	"41.9"	"4.5"	"14.6"	"35.6"	"37.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96DV4"	"39S ribosomal protein L38, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL38 PE=1 SV=2"	"2"	"1"	"4"	"1"	"380"	"44.6"	"7.53"	"568.42"	"5.07"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	""	"Pf01161"	"64978"	"ENSG00000204316"	"MRPL38"	"B3KN96; hsa:64978; Q96DV4; Q96Q66; Q9P0B9"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"173.7"	"199.8"	"881.2"	"210.6"	"215.2"	"152.9"	"1139.0"	"115.1"	"207.1"	"131.5"	"172.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22059"	"Oxysterol-binding protein 1 OS=Homo sapiens OX=9606 GN=OSBP PE=1 SV=1"	"3"	"2"	"3"	"2"	"807"	"89.4"	"7.30"	"258.26"	"5.07"	"1"	"2"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf00169, Pf01237"	"5007"	"ENSG00000110048"	"OSBP"	"hsa:5007; P22059; Q6P524"	"Sphingolipid de novo biosynthesis; Synthesis of bile acids and bile salts"	""	"2"	"0"	"67.8"	"69.8"	"215.8"	"73.6"	"76.4"	"56.3"	"215.8"	"40.1"	"68.1"	"59.0"	"70.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6NVY1"	"3-hydroxyisobutyryl-CoA hydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=HIBCH PE=1 SV=2"	"8"	"3"	"6"	"3"	"386"	"43.5"	"8.19"	"1313.75"	"5.07"	"3"	"1"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf16113"	"26275"	"ENSG00000198130"	"HIBCH"	"D3DPI4; hsa:26275; Q53GA8; Q53GF2; Q53RF7; Q53TC6; Q6NVY1; Q92931; Q9BS94"	"Branched-chain amino acid catabolism"	"Amino acid metabolism"	"2"	"0"	"82.8"	"86.3"	"266.6"	"94.4"	"57.4"	"26.0"	"412.6"	"35.8"	"46.6"	"49.4"	"97.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13798"	"Acylamino-acid-releasing enzyme OS=Homo sapiens OX=9606 GN=APEH PE=1 SV=4"	"3"	"3"	"4"	"3"	"732"	"81.2"	"5.48"	"585.75"	"5.06"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"non-structural extracellular;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00326, Pf19283"	"327"	"ENSG00000164062"	"APEH"	"hsa:327; P13798; Q9BQ33; Q9P0Y2"	"Neutrophil degranulation; Eukaryotic Translation Termination"	""	"2"	"0"	"235.7"	"255.8"	"813.9"	"223.6"	"213.0"	"154.4"	"987.9"	"160.2"	"189.6"	"148.1"	"134.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15427"	"Splicing factor 3B subunit 4 OS=Homo sapiens OX=9606 GN=SF3B4 PE=1 SV=1"	"6"	"2"	"4"	"2"	"424"	"44.4"	"8.56"	"633.17"	"5.06"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00076"	"10262"	"ENSG00000143368"	"SF3B4"	"hsa:10262; Q15427; Q5SZ63"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"mRNA processing"	"3"	"0"	"92.5"	"108.8"	"281.4"	"92.3"	"121.1"	"84.8"	"284.2"	"60.0"	"98.8"	"60.2"	"58.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61927"	"60S ribosomal protein L37 OS=Homo sapiens OX=9606 GN=RPL37 PE=1 SV=2"	"27"	"4"	"5"	"4"	"97"	"11.1"	"11.74"	"837.47"	"5.05"	"3"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf01907"	"6167"	"ENSG00000145592"	"RPL37"	"B2R4H2; hsa:6167; P02403; P61927; Q6IBB4; Q99883"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"813.1"	"991.8"	"2808.6"	"815.4"	"847.0"	"739.9"	"4183.7"	"430.4"	"649.2"	"440.3"	"374.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y291"	"28S ribosomal protein S33, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS33 PE=1 SV=1"	"20"	"2"	"3"	"2"	"106"	"12.6"	"10.11"	"322.79"	"5.04"	"1"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf08293"	"51650"	"ENSG00000090263"	"MRPS33"	"hsa:51650; Q9Y291"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"166.8"	"196.5"	"501.0"	"183.7"	"179.7"	"149.0"	"498.6"	"64.6"	"85.2"	"90.5"	"86.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15599"	"Na(+)/H(+) exchange regulatory cofactor NHE-RF2 OS=Homo sapiens OX=9606 GN=SLC9A3R2 PE=1 SV=2"	"4"	"1"	"2"	"1"	"337"	"37.4"	"7.93"	"665.32"	"5.04"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00595, Pf09007"	"9351"	"ENSG00000065054"	"NHERF2"	"D3DU84; D3DU85; H3BSV6; hsa:9351; O00272; O00556; Q15599; Q3KQY7"	""	""	"0"	"0"	"6.0"	"7.7"	"11.1"	"4.5"	"6.6"	"6.1"	"20.1"	"6.7"	"24.2"	"24.7"	"25.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2W1"	"Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2"	"3"	"2"	"3"	"2"	"955"	"108.6"	"10.15"	"353.31"	"5.02"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf15440"	"9967"	"ENSG00000054118"	"THRAP3"	"D3DPS5; hsa:9967; Q5VTK6; Q9Y2W1"	"PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation"	"Interactome of polycomb repressive complex 2 (PRC2)"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06730"	"Eukaryotic translation initiation factor 4E OS=Homo sapiens OX=9606 GN=EIF4E PE=1 SV=2"	"13"	"3"	"5"	"3"	"217"	"25.1"	"6.15"	"939.55"	"5.01"	"3"	"2"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01652"	"1977"	"ENSG00000151247"	"EIF4E"	"B7Z6V1; D6RCQ6; hsa:1977; P06730; Q96E95"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Deadenylation of mRNA; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; mTORC1-mediated signalling"	"Translation factors; Leptin signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Interleukin-1 (IL-1) structural pathway; Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4); Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; 4-hydroxytamoxifen, dexamethasone, and retinoic acids regulation of p27 expression; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Head and neck squamous cell carcinoma; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; Host-pathogen interaction of human coronaviruses - MAPK signaling; Hypertrophy model; Interferon type I signaling pathways"	"30"	"0"	"308.2"	"332.0"	"1091.0"	"296.8"	"269.4"	"203.2"	"1393.3"	"228.7"	"338.7"	"329.6"	"509.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15084"	"Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A OS=Homo sapiens OX=9606 GN=ANKRD28 PE=1 SV=5"	"2"	"2"	"4"	"1"	"1053"	"112.9"	"6.25"	"632.95"	"5.00"	"2"	"2"	""	"cytosol;nucleus"	""	"Pf00023, Pf13637"	"23243"	"ENSG00000206560"	"ANKRD28"	"B4DES5; hsa:23243; O15084; Q1WWL4; Q29RW6; Q3B857; Q6ULS0; Q6ZT57"	"Telomere Extension By Telomerase; COPII-mediated vesicle transport"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"P51571"	"Translocon-associated protein subunit delta OS=Homo sapiens OX=9606 GN=SSR4 PE=1 SV=1"	"7"	"1"	"2"	"1"	"173"	"19.0"	"6.15"	"539.47"	"4.99"	"1"	"1"	""	"other membranes;ER/Golgi;other cell component"	""	"Pf05404"	"6748"	"ENSG00000180879"	"SSR4"	"A8K378; hsa:6748; P51571; Q53XY1"	"SRP-dependent cotranslational protein targeting to membrane"	"VEGFA-VEGFR2 signaling"	"2"	"0"	"299.2"	"308.2"	"1174.2"	"237.8"	"232.9"	"159.1"	"1025.3"	"83.0"	"138.9"	"81.9"	"78.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86YS7"	"C2 domain-containing protein 5 OS=Homo sapiens OX=9606 GN=C2CD5 PE=1 SV=1"	"3"	"3"	"5"	"3"	"1000"	"110.4"	"5.69"	"926.83"	"4.97"	"3"	"2"	"transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00168"	"9847"	"ENSG00000111731"	"C2CD5"	"B4DJ03; B4DRN7; B7ZLL0; F5H2A1; F5H5R1; hsa:9847; O60280; Q17RY7; Q7Z619; Q86SU3; Q86YS7"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"	""	"1"	"0"	"19.4"	"19.2"	"77.9"	"17.6"	"17.2"	"16.3"	"117.9"	"81.8"	"224.8"	"256.5"	"244.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N488"	"RING1 and YY1-binding protein OS=Homo sapiens OX=9606 GN=RYBP PE=1 SV=2"	"9"	"1"	"1"	"1"	"228"	"24.8"	"9.63"	""	"4.96"	""	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00641, Pf17219"	"23429"	"ENSG00000163602; ENSG00000281766"	"RYBP"	"hsa:23429; Q8N488; Q9P2W5; Q9UMW4"	"Transcriptional Regulation by E2F6; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"	""	"2"	"0"	"5.3"	"9.0"	"47.0"	"11.2"	"10.6"	"15.7"	"64.1"	"10.4"	"12.9"	"9.0"	"4.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BRK5"	"45 kDa calcium-binding protein OS=Homo sapiens OX=9606 GN=SDF4 PE=1 SV=1"	"5"	"1"	"2"	"1"	"362"	"41.8"	"4.86"	"515.55"	"4.96"	"1"	"1"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf13202, Pf13499"	"51150"	""	"SDF4"	"B1AME5; B1AME6; B2RDF1; B4DSM1; hsa:51150; Q53G52; Q53HQ9; Q8NBQ3; Q96AA1; Q9BRK5; Q9NZP7; Q9UN53"	""	""	"0"	"0"	"21.0"	"20.3"	"112.1"	"31.0"	"21.3"	"21.0"	"104.0"	"6.8"	"12.6"	"10.7"	"5.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7KZ85"	"Transcription elongation factor SPT6 OS=Homo sapiens OX=9606 GN=SUPT6H PE=1 SV=2"	"3"	"4"	"5"	"4"	"1726"	"198.9"	"4.91"	"1205.07"	"4.95"	"3"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00575, Pf14632, Pf14633, Pf14635, Pf14639, Pf14641, Pf17674"	"6830"	"ENSG00000109111"	"SUPT6H"	"A7E2B4; hsa:6830; Q15737; Q6GMQ4; Q7KYW9; Q7KZ85; Q7LDK4; Q8N526; Q92775; Q96AH3; Q9BTH9; Q9BTI2"	"Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events"	""	"3"	"0"	"134.6"	"137.0"	"382.6"	"138.9"	"124.7"	"133.8"	"343.8"	"60.3"	"103.0"	"67.1"	"68.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35573"	"Glycogen debranching enzyme OS=Homo sapiens OX=9606 GN=AGL PE=1 SV=3"	"1"	"2"	"3"	"2"	"1532"	"174.7"	"6.76"	"285.08"	"4.94"	"1"	"2"	"other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf06202, Pf14699, Pf14701, Pf14702"	"178"	"ENSG00000162688"	"AGL"	"A6NCX7; A6NEK2; D3DT51; hsa:178; P35573; P78354; P78544; Q59H92; Q6AZ90; Q9UF08"	"Neutrophil degranulation; Glycogen breakdown (glycogenolysis)"	"Glycogen synthesis and degradation"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12907"	"Vesicular integral-membrane protein VIP36 OS=Homo sapiens OX=9606 GN=LMAN2 PE=1 SV=1"	"7"	"2"	"4"	"2"	"356"	"40.2"	"6.95"	"583.44"	"4.94"	"2"	"2"	"transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf03388"	"10960"	"ENSG00000169223"	"LMAN2"	"hsa:10960; Q12907; Q53HH1"	"COPII-mediated vesicle transport; Cargo concentration in the ER"	""	"2"	"0"	"76.9"	"85.2"	"253.7"	"69.4"	"69.2"	"53.9"	"252.5"	"36.8"	"52.5"	"42.9"	"46.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H9C1"	"Spermatogenesis-defective protein 39 homolog OS=Homo sapiens OX=9606 GN=VIPAS39 PE=1 SV=1"	"4"	"1"	"1"	"1"	"493"	"57.0"	"7.40"	""	"4.93"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf04840"	"63894"	"ENSG00000151445"	"VIPAS39"	"B4DPI6; hsa:63894; O95434; Q9H7E1; Q9H9C1; Q9H9I9"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"O95336"	"6-phosphogluconolactonase OS=Homo sapiens OX=9606 GN=PGLS PE=1 SV=2"	"7"	"2"	"4"	"2"	"258"	"27.5"	"6.05"	"557.96"	"4.92"	"2"	"2"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf01182"	"25796"	"ENSG00000130313"	"PGLS"	"hsa:25796; O95336"	"Pentose phosphate pathway"	"Pentose phosphate metabolism"	"2"	"0"	"57.7"	"80.6"	"400.3"	"84.9"	"72.6"	"69.0"	"549.3"	"43.7"	"63.7"	"39.3"	"38.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BRL6"	"Serine/arginine-rich splicing factor 8 OS=Homo sapiens OX=9606 GN=SRSF8 PE=1 SV=1"	"5"	"2"	"4"	"2"	"282"	"32.3"	"11.72"	"502.31"	"4.91"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	""	"Pf00076"	"10929"	"ENSG00000263465"	"SRSF8"	"B2R6B8; hsa:10929; Q6PF01; Q96TA3; Q9BRL6"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	""	"2"	"0"	"290.0"	"337.1"	"1041.1"	"224.6"	"208.4"	"191.2"	"1223.7"	"156.5"	"178.0"	"132.4"	"125.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15270"	"Serine palmitoyltransferase 2 OS=Homo sapiens OX=9606 GN=SPTLC2 PE=1 SV=1"	"3"	"1"	"2"	"1"	"562"	"62.9"	"7.78"	"414.07"	"4.91"	"1"	"1"	"other metabolic processes;other biological processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf00155"	"9517"	"ENSG00000100596"	"SPTLC2"	"hsa:9517; O15270; Q16685"	"Sphingolipid de novo biosynthesis"	"Sphingolipid pathway; Sphingolipid metabolism: integrated pathway; Biosynthesis and turnover of 1-deoxy-sphingoid bases"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q08378"	"Golgin subfamily A member 3 OS=Homo sapiens OX=9606 GN=GOLGA3 PE=1 SV=2"	"1"	"2"	"4"	"2"	"1498"	"167.3"	"5.44"	"502.37"	"4.91"	"2"	"2"	""	"other membranes;cytosol;ER/Golgi;nucleus"	""	""	"2802"	"ENSG00000090615"	"GOLGA3"	"A5PKX6; hsa:2802; O43241; Q08378; Q6P9C7; Q86XW3; Q8TDA9; Q8WZA3"	"RND2 GTPase cycle"	""	"1"	"0"	"7.6"	"4.8"	"32.9"	"7.5"	"8.7"	"7.2"	"28.9"	"3.1"	"2.9"	"4.2"	"3.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P24941"	"Cyclin-dependent kinase 2 OS=Homo sapiens OX=9606 GN=CDK2 PE=1 SV=2"	"5"	"1"	"2"	"1"	"298"	"33.9"	"8.68"	"537.67"	"4.90"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"1017"	"ENSG00000123374"	"CDK2"	"A8K7C6; hsa:1017; O75100; P24941"	"TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; Regulation of TP53 Degradation; SCF(Skp2)-mediated degradation of p27/p21; Regulation of TP53 Activity through Phosphorylation; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; G2 Phase; Cyclin D associated events in G1; Defective binding of RB1 mutants to E2F1,(E2F2, E2F3); Telomere Extension By Telomerase; Regulation of APC/C activators between G1/S and early anaphase; Senescence-Associated Secretory Phenotype (SASP); Factors involved in megakaryocyte development and platelet production; Processing of DNA double-strand break ends; Cyclin A/B1/B2 associated events during G2/M transition; Meiotic recombination; DNA Damage/Telomere Stress Induced Senescence; Transcriptional regulation of granulopoiesis; G0 and Early G1; Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes; p53-Dependent G1 DNA Damage Response; PTK6 Regulates Cell Cycle"	"miRNA regulation of DNA damage response; Cell cycle; Thyroid stimulating hormone (TSH) signaling pathway; Glioblastoma signaling pathways; Oncostatin M signaling pathway; Spinal cord injury; Retinoblastoma gene in cancer; Aryl hydrocarbon receptor pathway; Vitamin D receptor pathway; PI3K-Akt signaling pathway; G1 to S cell cycle control; Measles virus infection; Small cell lung cancer; DNA replication; p53 transcriptional gene network; Pleural mesothelioma; Sphingolipid metabolism in senescence; Urotensin-II-mediated signaling pathway; ID signaling pathway; TROP2 regulatory signaling; DNA damage response"	"47"	"0"	"19.0"	"15.6"	"57.3"	"26.4"	"15.7"	"15.0"	"50.1"	"7.4"	"10.1"	"16.8"	"28.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BW85"	"Splicing factor YJU2 OS=Homo sapiens OX=9606 GN=YJU2 PE=1 SV=1"	"4"	"1"	"2"	"1"	"323"	"37.1"	"5.92"	"452.87"	"4.90"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf04502"	"55702"	"ENSG00000105248"	"YJU2"	"hsa:55702; O75270; Q9BW85; Q9H862; Q9NW16"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"60.5"	"41.8"	"99.3"	"35.0"	"34.4"	"37.8"	"117.5"	"19.1"	"31.7"	"26.6"	"24.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14684"	"Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3"	"3"	"2"	"4"	"2"	"758"	"84.4"	"9.76"	"515.20"	"4.89"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf05997"	"23076"	"ENSG00000160208"	"RRP1B"	"hsa:23076; Q14684; Q8TBZ4"	""	""	"0"	"0"	"72.1"	"70.2"	"204.1"	"75.8"	"67.0"	"58.6"	"293.4"	"95.6"	"149.1"	"105.6"	"133.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P21964"	"Catechol O-methyltransferase OS=Homo sapiens OX=9606 GN=COMT PE=1 SV=2"	"7"	"1"	"2"	"1"	"271"	"30.0"	"5.47"	"646.27"	"4.88"	"1"	"1"	"other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf01596"	"1312"	"ENSG00000093010"	"COMT"	"A8MPV9; hsa:1312; P21964; Q6IB07; Q6ICE6; Q9BWC7"	"Potential therapeutics for SARS; Methylation; Enzymatic degradation of dopamine by COMT; Enzymatic degradation of Dopamine by monoamine oxidase"	"Dopamine metabolism; Flavan-3-ol metabolic pathway; MTHFR deficiency; 22q11.2 copy number variation syndrome; Primary ovarian insufficiency; Biogenic amine synthesis; Estrogen metabolism; Metapathway biotransformation Phase I and II; Methylation pathways"	"13"	"0"	"20.7"	"10.8"	"72.5"	"13.5"	"14.3"	"7.8"	"64.5"	"6.3"	"6.1"	"9.6"	"14.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5VUA4"	"Zinc finger protein 318 OS=Homo sapiens OX=9606 GN=ZNF318 PE=1 SV=2"	"1"	"2"	"4"	"2"	"2279"	"251.0"	"7.20"	"650.99"	"4.87"	"2"	"2"	"cell cycle OR cell proliferation;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	""	"24149"	"ENSG00000171467"	"ZNF318"	"hsa:24149; O94796; Q4G0E4; Q5VUA4; Q8NEM6; Q9UNU8; Q9Y2W9"	""	"Androgen receptor signaling pathway"	"1"	"0"	"14.0"	"15.4"	"45.6"	"12.3"	"17.3"	"9.9"	"54.7"	"11.1"	"14.1"	"16.8"	"14.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BVG4"	"Protein PBDC1 OS=Homo sapiens OX=9606 GN=PBDC1 PE=1 SV=1"	"9"	"2"	"4"	"2"	"233"	"26.0"	"4.79"	"524.78"	"4.86"	"2"	"1"	""	""	""	"Pf04669"	"51260"	"ENSG00000102390"	"PBDC1"	"hsa:51260; Q9BVG4"	""	""	"0"	"0"	"353.1"	"236.9"	"304.9"	"72.7"	"72.3"	"56.8"	"252.9"	"47.2"	"50.9"	"44.0"	"39.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NEZ5"	"F-box only protein 22 OS=Homo sapiens OX=9606 GN=FBXO22 PE=1 SV=1"	"5"	"2"	"3"	"2"	"403"	"44.5"	"7.03"	"321.89"	"4.86"	"1"	"2"	"protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"cytosol;cytoskeleton;nucleus"	"other molecular function"	"Pf00646, Pf10442"	"26263"	"ENSG00000167196"	"FBXO22"	"hsa:26263; Q0D2P8; Q6PIL5; Q8IXW3; Q8NEZ5; Q9H824; Q9UKC0"	"Antigen processing: Ubiquitination & Proteasome degradation; Neddylation"	""	"2"	"0"	"62.1"	"81.9"	"275.8"	"76.7"	"72.4"	"57.4"	"312.7"	"52.8"	"70.6"	"57.9"	"64.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99536"	"Synaptic vesicle membrane protein VAT-1 homolog OS=Homo sapiens OX=9606 GN=VAT1 PE=1 SV=2"	"5"	"2"	"4"	"2"	"393"	"41.9"	"6.29"	"644.66"	"4.85"	"2"	"2"	"other biological processes"	"non-structural extracellular;other membranes;mitochondrion;other cytoplasmic organelle"	"other molecular function"	"Pf08240, Pf13602"	"10493"	"ENSG00000108828"	"VAT1"	"A8K345; B0AZP7; B4DPX4; hsa:10493; Q13035; Q5BKZ7; Q96A39; Q99536; Q9BUT8"	"Neutrophil degranulation"	""	"1"	"0"	"94.3"	"83.4"	"348.3"	"92.0"	"82.2"	"69.5"	"414.9"	"47.8"	"77.9"	"56.6"	"74.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92905"	"COP9 signalosome complex subunit 5 OS=Homo sapiens OX=9606 GN=COPS5 PE=1 SV=4"	"6"	"2"	"4"	"2"	"334"	"37.6"	"6.54"	"656.60"	"4.84"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01398, Pf18323"	"10987"	"ENSG00000121022"	"COPS5"	"hsa:10987; O15386; Q6AW95; Q86WQ4; Q92905; Q9BQ17"	"Formation of TC-NER Pre-Incision Complex; Cargo recognition for clathrin-mediated endocytosis; Neddylation; DNA Damage Recognition in GG-NER"	""	"4"	"0"	"145.3"	"200.5"	"515.0"	"164.9"	"150.5"	"129.3"	"578.9"	"78.3"	"119.0"	"98.8"	"91.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q32MZ4"	"Leucine-rich repeat flightless-interacting protein 1 OS=Homo sapiens OX=9606 GN=LRRFIP1 PE=1 SV=2"	"3"	"2"	"4"	"2"	"808"	"89.2"	"4.65"	"615.50"	"4.84"	"2"	"2"	"RNA metabolism OR transcription;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09738"	"9208"	"ENSG00000124831"	"LRRFIP1"	"E9PGZ2; hsa:9208; O75766; O75799; Q32MZ4; Q32MZ5; Q53T49; Q6PKG2; Q9Y607"	"Signaling by cytosolic FGFR1 fusion mutants; Signaling by FGFR1 in disease; LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production"	"IL-18 signaling pathway; 2q37 copy number variation syndrome"	"5"	"0"	"22.3"	"21.3"	"60.7"	"19.9"	"20.4"	"11.0"	"91.6"	"11.8"	"17.4"	"9.8"	"15.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14635"	"G2/mitotic-specific cyclin-B1 OS=Homo sapiens OX=9606 GN=CCNB1 PE=1 SV=1"	"5"	"2"	"3"	"2"	"433"	"48.3"	"7.47"	"400.39"	"4.83"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00134, Pf02984"	"891"	"ENSG00000134057"	"CCNB1"	"A8K066; hsa:891; P14635; Q5TZP9"	"Regulation of PLK1 Activity at G2/M Transition; The role of GTSE1 in G2/M progression after G2 checkpoint; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Resolution of Sister Chromatid Cohesion; Nuclear Pore Complex (NPC) Disassembly; APC/C:Cdc20 mediated degradation of Cyclin B; Phosphorylation of the APC/C; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; Cyclin A/B1/B2 associated events during G2/M transition; Transcriptional regulation by RUNX2; MASTL Facilitates Mitotic Progression; E2F-enabled inhibition of pre-replication complex formation; Golgi Cisternae Pericentriolar Stack Reorganization; Condensation of Prophase Chromosomes; Initiation of Nuclear Envelope (NE) Reformation; Polo-like kinase mediated events; Condensation of Prometaphase Chromosomes; Activation of NIMA Kinases NEK9, NEK6, NEK7; G2/M DNA replication checkpoint; Depolymerization of the Nuclear Lamina; Phosphorylation of Emi1"	"AMP-activated protein kinase signaling; miRNA regulation of DNA damage response; Cell cycle; Retinoblastoma gene in cancer; ATM signaling pathway; G1 to S cell cycle control; GDNF signaling; DNA damage response"	"31"	"0"	"12.1"	"10.1"	"32.1"	"7.9"	"5.5"	"6.0"	"22.5"	"2.8"	"5.5"	"12.5"	"14.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95573"	"Long-chain-fatty-acid--CoA ligase 3 OS=Homo sapiens OX=9606 GN=ACSL3 PE=1 SV=3"	"3"	"2"	"3"	"2"	"720"	"80.4"	"8.38"	"248.75"	"4.83"	"1"	"2"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00501"	"2181"	"ENSG00000123983"	"ACSL3"	"hsa:2181; O95573; Q60I92; Q8IUM9"	"Synthesis of very long-chain fatty acyl-CoAs; Intracellular metabolism of fatty acids regulates insulin secretion"	"Fatty acid beta-oxidation; Fatty acid biosynthesis; Mitochondrial long chain fatty acid beta-oxidation; PPAR signaling pathway; Ferroptosis; Thermogenesis; Ciliary landscape; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Omega-3 / omega-6 fatty acid synthesis; Omega-9 fatty acid synthesis; Fatty acid transporters; Mitochondrial fatty acid oxidation disorders"	"14"	"0"	"201.8"	"193.0"	"712.5"	"140.1"	"121.5"	"105.5"	"887.2"	"80.5"	"112.2"	"78.6"	"75.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95777"	"U6 snRNA-associated Sm-like protein LSm8 OS=Homo sapiens OX=9606 GN=LSM8 PE=1 SV=3"	"20"	"1"	"2"	"1"	"96"	"10.4"	"4.48"	"475.56"	"4.83"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf01423"	"51691"	"ENSG00000128534"	"LSM8"	"hsa:51691; O95777"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"23.3"	"20.3"	"69.6"	"17.1"	"21.4"	"19.8"	"74.9"	"17.7"	"20.7"	"18.4"	"21.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50213"	"Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3A PE=1 SV=1"	"5"	"2"	"4"	"2"	"366"	"39.6"	"6.92"	"689.00"	"4.83"	"2"	"2"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00180"	"3419"	"ENSG00000166411"	"IDH3A"	"D3DW83; hsa:3419; P50213; Q9H3X0"	"Citric acid cycle (TCA cycle)"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Metabolic reprogramming in colon cancer; TCA cycle (aka Krebs or citric acid cycle)"	"4"	"0"	"133.9"	"153.2"	"608.5"	"158.3"	"136.0"	"104.6"	"709.0"	"89.8"	"128.6"	"101.5"	"123.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35222"	"Catenin beta-1 OS=Homo sapiens OX=9606 GN=CTNNB1 PE=1 SV=1"	"3"	"3"	"5"	"1"	"781"	"85.4"	"5.86"	"843.69"	"4.83"	"3"	"2"	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00514"	"1499"	"ENSG00000168036"	"CTNNB1"	"A8K1L7; hsa:1499; P35222; Q8NEW9; Q8NI94; Q9H391"	"Somitogenesis; Deactivation of the beta-catenin transactivating complex; InlA-mediated entry of Listeria monocytogenes into host cells; RHO GTPases activate IQGAPs; Formation of paraxial mesoderm; Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1); Formation of axial mesoderm; Myogenesis; Transcriptional Regulation by VENTX; Ca2+ pathway; Disassembly of the destruction complex and recruitment of AXIN to the membrane; Beta-catenin phosphorylation cascade; Signaling by GSK3beta mutants; CTNNB1 S33 mutants aren't phosphorylated; CTNNB1 S37 mutants aren't phosphorylated; CTNNB1 S45 mutants aren't phosphorylated; CTNNB1 T41 mutants aren't phosphorylated; Cardiogenesis; Germ layer formation at gastrulation; Formation of definitive endoderm; VEGFR2 mediated vascular permeability; Adherens junctions interactions; Regulation of CDH11 function; Regulation of CDH19 Expression and Function; CDH11 homotypic and heterotypic interactions; Binding of TCF/LEF:CTNNB1 to target gene promoters; RUNX3 regulates WNT signaling; Apoptotic cleavage of cell adhesion  proteins; LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production"	"Androgen receptor signaling pathway; MicroRNAs in cardiomyocyte hypertrophy; Heart development; TNF-related weak inducer of apoptosis (TWEAK) signaling pathway; Alzheimer's disease and miRNA effects; Neural crest differentiation; Arrhythmogenic right ventricular cardiomyopathy; Pathogenic Escherichia coli infection; Corticotropin-releasing hormone signaling pathway; Adipogenesis; Gastric cancer network 2; Brain-derived neurotrophic factor (BDNF) signaling pathway; Primary focal segmental glomerulosclerosis (FSGS); Endoderm differentiation; Ectoderm differentiation; Extracellular vesicle-mediated signaling in recipient cells; Focal adhesion; Ectoderm differentiation; RAC1/PAK1/p38/MMP2 pathway; Wnt signaling pathway; Regulation of Wnt / B-catenin signaling by small molecule compounds; Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; Embryonic stem cell pluripotency pathways; H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity; OSX and miRNAs in tooth development; Wnt signaling pathway and pluripotency; PTF1A related regulatory pathway; Wnt signaling in kidney disease; Endometrial cancer; Chromosomal and microsatellite instability in colorectal cancer ; Epithelial to mesenchymal transition in colorectal cancer; lncRNA in canonical Wnt signaling and colorectal cancer; Breast cancer pathway; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Ciliary landscape; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; Gastrin signaling pathway; Head and neck squamous cell carcinoma; Thyroid hormones production and peripheral downstream signaling effects; IL-18 signaling pathway; Osteoblast differentiation and related diseases; TGF-beta receptor signaling in skeletal dysplasias; Genes controlling nephrogenesis; GDNF/RET signaling axis; Mammalian disorder of sexual development; Influence of laminopathies on Wnt signaling; Overlap between signal transduction pathways contributing to LMNA laminopathies; 1q21.1 copy number variation syndrome; 7q11.23 copy number variation syndrome; Development of ureteric collection system; Pleural mesothelioma; Alzheimer's disease; Urotensin-II-mediated signaling pathway; Markers of kidney cell lineage; TROP2 regulatory signaling; A network map of Macrophage-stimulating protein (MSP) signaling; TGF-beta receptor signaling; Sudden infant death syndrome (SIDS) susceptibility pathways; DNA damage response (only ATM dependent)"	"95"	"0"	"9.0"	"13.3"	"40.4"	"6.4"	"5.8"	"2.4"	"47.4"	"4.7"	"5.0"	"4.0"	"4.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BYN8"	"28S ribosomal protein S26, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS26 PE=1 SV=1"	"11"	"2"	"3"	"2"	"205"	"24.2"	"10.39"	"950.47"	"4.81"	"2"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	""	"Pf14943"	"64949"	"ENSG00000125901"	"MRPS26"	"hsa:64949; Q96Q58; Q9BYN8"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"193.4"	"202.0"	"700.0"	"207.5"	"181.6"	"157.3"	"1002.0"	"117.7"	"178.4"	"120.6"	"133.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23258"	"Tubulin gamma-1 chain OS=Homo sapiens OX=9606 GN=TUBG1 PE=1 SV=2"	"4"	"2"	"5"	"2"	"451"	"51.1"	"6.14"	"1021.84"	"4.81"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis"	"cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00091, Pf03953"	"7283"	"ENSG00000131462"	"TUBG1"	"hsa:7283; P23258; Q53X79; Q9BW59"	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"Alstrom syndrome"	"8"	"0"	"162.1"	"186.1"	"607.5"	"157.1"	"153.1"	"115.5"	"657.8"	"127.4"	"196.9"	"291.1"	"502.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09012"	"U1 small nuclear ribonucleoprotein A OS=Homo sapiens OX=9606 GN=SNRPA PE=1 SV=3"	"6"	"2"	"5"	"1"	"282"	"31.3"	"9.83"	"786.88"	"4.81"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6626"	"ENSG00000077312"	"SNRPA"	"hsa:6626; P09012"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"0"	"45.2"	"41.5"	"126.7"	"40.8"	"42.1"	"36.2"	"170.3"	"25.5"	"34.3"	"30.5"	"25.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96G03"	"Phosphoglucomutase-2 OS=Homo sapiens OX=9606 GN=PGM2 PE=1 SV=4"	"5"	"3"	"4"	"3"	"612"	"68.2"	"6.73"	"575.62"	"4.81"	"2"	"2"	"other metabolic processes"	"non-structural extracellular;cytosol;other cell component"	"other molecular function"	"Pf00408, Pf02878, Pf02879, Pf02880"	"55276"	"ENSG00000169299"	"PGM2"	"B4E0G8; hsa:55276; Q53FP5; Q5QTR0; Q96G03; Q9H0P9; Q9NV22"	"Neutrophil degranulation; Pentose phosphate pathway"	"Clear cell renal cell carcinoma pathways; Glucuronidation"	"4"	"0"	"22.6"	"31.0"	"121.6"	"26.5"	"17.5"	"14.0"	"164.4"	"17.2"	"18.2"	"12.0"	"6.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35244"	"Replication protein A 14 kDa subunit OS=Homo sapiens OX=9606 GN=RPA3 PE=1 SV=1"	"14"	"1"	"2"	"1"	"121"	"13.6"	"5.08"	"457.19"	"4.80"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf08661"	"6119"	"ENSG00000106399"	"RPA3"	"hsa:6119; P35244; Q549U6"	"HSF1 activation; Fanconi Anemia Pathway; Regulation of HSF1-mediated heat shock response; Regulation of TP53 Activity through Phosphorylation; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Meiotic recombination; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Removal of the Flap Intermediate; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"Retinoblastoma gene in cancer; G1 to S cell cycle control; DNA replication; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"36"	"0"	"25.1"	"29.2"	"100.5"	"33.9"	"28.0"	"25.0"	"107.5"	"22.0"	"37.3"	"28.6"	"34.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q08554"	"Desmocollin-1 OS=Homo sapiens OX=9606 GN=DSC1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"894"	"99.9"	"5.43"	"358.23"	"4.80"	"1"	"1"	"cell adhesion"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00028, Pf01049, Pf08758"	"1823"	"ENSG00000134765"	"DSC1"	"hsa:1823; Q08554; Q9HB01"	"Neutrophil degranulation; Formation of the cornified envelope"	"VEGFA-VEGFR2 signaling"	"4"	"0"	"109.1"	"77.1"	"115.7"	"53.9"	"60.2"	"45.3"	"135.8"	"38.2"	"52.6"	"39.3"	"46.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UHR5"	"SAP30-binding protein OS=Homo sapiens OX=9606 GN=SAP30BP PE=1 SV=1"	"4"	"1"	"2"	"1"	"308"	"33.9"	"4.84"	"583.54"	"4.79"	"1"	"1"	"other biological processes"	"cytoskeleton;nucleus"	""	"Pf07818"	"29115"	"ENSG00000161526"	"SAP30BP"	"B3KML7; hsa:29115; Q8N1R5; Q8TDR8; Q96D27; Q9UHR5"	"NoRC negatively regulates rRNA expression"	""	"1"	"0"	"10.2"	"11.8"	"33.8"	"12.8"	"9.5"	"9.2"	"33.1"	"6.2"	"8.2"	"4.0"	"5.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95707"	"Ribonuclease P protein subunit p29 OS=Homo sapiens OX=9606 GN=POP4 PE=1 SV=2"	"9"	"2"	"3"	"2"	"220"	"25.4"	"10.07"	"244.90"	"4.79"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01868"	"10775"	"ENSG00000105171"	"POP4"	"hsa:10775; O95707; Q5XKL7; Q6FHW9; Q9UQQ3"	"tRNA processing in the nucleus"	""	"1"	"0"	"31.6"	"45.7"	"97.3"	"22.0"	"31.2"	"25.6"	"104.5"	"17.5"	"28.9"	"21.5"	"24.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04908"	"Histone H2A type 1-B/E OS=Homo sapiens OX=9606 GN=H2AC4 PE=1 SV=2"	"22"	"2"	"4"	"2"	"130"	"14.1"	"11.05"	"585.72"	"4.78"	"2"	"2"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125, Pf16211"	"3012; 8335"	"ENSG00000277075; ENSG00000278463"	"H2AC4; H2AC8"	"hsa:3012; hsa:8335; P04908; P28001; Q76P63"	"HCMV Early Events; Deposition of new CENPA-containing nucleosomes at the centromere; B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; Amyloid fiber formation; Meiotic synapsis; HCMV Late Events; UCH proteinases; Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Transcriptional regulation by small RNAs; Formation of the beta-catenin:TCF transactivating complex; Oxidative Stress Induced Senescence; HDACs deacetylate histones; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Metalloprotease DUBs; Pre-NOTCH Transcription and Translation; Senescence-Associated Secretory Phenotype (SASP); RMTs methylate histone arginines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; HATs acetylate histones; RNA Polymerase I Promoter Escape; Meiotic recombination; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Packaging Of Telomere Ends; Condensation of Prophase Chromosomes; DNA Damage/Telomere Stress Induced Senescence; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis"	"Proteasome degradation"	"42"	"0"	"163.0"	"222.4"	"609.0"	"152.0"	"152.9"	"128.3"	"564.7"	"69.2"	"77.1"	"61.9"	"68.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95819"	"Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens OX=9606 GN=MAP4K4 PE=1 SV=2"	"2"	"2"	"4"	"1"	"1239"	"142.0"	"7.46"	"590.39"	"4.78"	"2"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"other cell component"	"cytoskeletal activity;kinase activity;other molecular function"	"Pf00069, Pf00780"	"9448"	"ENSG00000071054"	"MAP4K4"	"E7ESS2; hsa:9448; O75172; O95819; Q9NST7"	"Oxidative Stress Induced Senescence"	"MAPK signaling pathway; Angiopoietin-like protein 8 regulatory pathway; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-YAP signaling; Insulin signaling; Pleural mesothelioma"	"7"	"0"	"20.4"	"14.4"	"61.5"	"17.9"	"16.4"	"16.5"	"32.5"	"5.2"	"7.4"	"9.0"	"8.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q00013"	"55 kDa erythrocyte membrane protein OS=Homo sapiens OX=9606 GN=MPP1 PE=1 SV=2"	"5"	"2"	"3"	"2"	"466"	"52.3"	"7.37"	"290.40"	"4.78"	"1"	"2"	"other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;kinase activity"	"Pf00018, Pf00595, Pf00625"	"4354"	"ENSG00000130830"	"MPP1"	"B4DZV5; G3XAI1; hsa:4354; Q00013; Q2TSB6; Q5J7V5"	"Sensory processing of sound by outer hair cells of the cochlea"	"MECP2 and associated Rett syndrome"	"2"	"0"	"124.8"	"156.2"	"495.4"	"129.1"	"119.9"	"96.3"	"543.6"	"80.5"	"116.4"	"88.2"	"88.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z4H3"	"5'-deoxynucleotidase HDDC2 OS=Homo sapiens OX=9606 GN=HDDC2 PE=1 SV=1"	"6"	"1"	"2"	"1"	"204"	"23.4"	"5.49"	"538.72"	"4.77"	"1"	"1"	""	""	"other molecular function"	"Pf13023"	"51020"	"ENSG00000111906"	"HDDC2"	"hsa:51020; Q5TDQ4; Q6NZ49; Q7Z4H3; Q9BTT2; Q9BV31; Q9Y3D1"	""	""	"0"	"0"	"65.6"	"77.0"	"440.2"	"70.0"	"84.1"	"48.0"	"519.5"	"36.0"	"46.7"	"37.7"	"36.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5T447"	"E3 ubiquitin-protein ligase HECTD3 OS=Homo sapiens OX=9606 GN=HECTD3 PE=1 SV=1"	"2"	"1"	"2"	"1"	"861"	"97.1"	"5.64"	"566.67"	"4.77"	"1"	"1"	"protein metabolism;other metabolic processes"	"other cell component"	"other molecular function"	"Pf00632, Pf03256"	"79654"	"ENSG00000126107"	"HECTD3"	"B3KPV7; B3KRH4; hsa:79654; Q5T447; Q5T448; Q9H783"	"Antigen processing: Ubiquitination & Proteasome degradation"	""	"1"	"0"	"5.9"	"7.2"	"36.9"	"9.6"	"5.7"	"3.9"	"43.2"	"4.6"	"7.1"	"3.1"	"2.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61106"	"Ras-related protein Rab-14 OS=Homo sapiens OX=9606 GN=RAB14 PE=1 SV=4"	"14"	"3"	"5"	"2"	"215"	"23.9"	"6.21"	"639.96"	"4.76"	"2"	"3"	"cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00071"	"51552"	"ENSG00000119396"	"RAB14"	"B3KR31; hsa:51552; P35287; P61106; Q5JVD4; Q6Q7K5; Q969L0; Q9UI11"	"Neutrophil degranulation; RAB geranylgeranylation; RAB GEFs exchange GTP for GDP on RABs; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Synthesis of PIPs at the plasma membrane"	"Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Ciliary landscape"	"7"	"0"	"50.3"	"46.7"	"120.7"	"56.0"	"50.5"	"42.8"	"171.4"	"31.0"	"76.1"	"49.9"	"41.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61204"	"ADP-ribosylation factor 3 OS=Homo sapiens OX=9606 GN=ARF3 PE=1 SV=2"	"12"	"2"	"4"	"2"	"181"	"20.6"	"7.43"	"578.79"	"4.76"	"2"	"2"	"transport"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf00025"	"377"	"ENSG00000134287"	"ARF3"	"A8K6G8; B7ZB63; hsa:377; P16587; P61204"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport; Synthesis of PIPs at the Golgi membrane"	""	"3"	"0"	"60.3"	"81.7"	"268.9"	"70.4"	"83.3"	"60.4"	"309.8"	"45.3"	"58.1"	"46.2"	"44.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95835"	"Serine/threonine-protein kinase LATS1 OS=Homo sapiens OX=9606 GN=LATS1 PE=1 SV=1"	"2"	"2"	"3"	"2"	"1130"	"126.8"	"8.70"	"332.22"	"4.75"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00627"	"9113"	"ENSG00000131023"	"LATS1"	"hsa:9113; O95835; Q6PKD0"	"Signaling by Hippo"	"Mesodermal commitment pathway; Transcription co-factors SKI and SKIL protein partners; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-YAP signaling; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; Leukocyte-intrinsic Hippo pathway functions; Pleural mesothelioma"	"9"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TC07"	"TBC1 domain family member 15 OS=Homo sapiens OX=9606 GN=TBC1D15 PE=1 SV=2"	"3"	"2"	"3"	"2"	"691"	"79.4"	"5.67"	"238.93"	"4.74"	"1"	"2"	"other biological processes"	"non-structural extracellular;other cell component"	"enzyme regulator activity"	"Pf00566, Pf12068"	"64786"	"ENSG00000121749"	"TBC1D15"	"B4DMT9; B9A6L6; hsa:64786; J3KNI9; Q8TC07; Q9HA83"	"TBC/RABGAPs"	""	"1"	"0"	"7.9"	"5.3"	"35.0"	"5.1"	"9.4"	"5.8"	"35.6"	"0.0"	"1.7"	"4.1"	"3.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q00059"	"Transcription factor A, mitochondrial OS=Homo sapiens OX=9606 GN=TFAM PE=1 SV=1"	"5"	"1"	"2"	"1"	"246"	"29.1"	"9.72"	"541.30"	"4.70"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;mitochondrion;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00505, Pf09011"	"7019"	"ENSG00000108064"	"TFAM"	"A8MRB2; A9QXC6; B5BU05; hsa:7019; Q00059; Q5U0C6"	"Mitochondrial transcription initiation; Transcriptional activation of mitochondrial biogenesis"	"Energy metabolism; NAD metabolism, sirtuins and aging; VEGFA-VEGFR2 signaling; Mitochondrial gene expression; Orexin receptor pathway; Sildenafil treatment"	"8"	"0"	"159.2"	"215.0"	"701.9"	"171.3"	"173.8"	"130.8"	"709.9"	"71.4"	"121.1"	"89.4"	"103.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P18887"	"DNA repair protein XRCC1 OS=Homo sapiens OX=9606 GN=XRCC1 PE=1 SV=2"	"5"	"3"	"5"	"3"	"633"	"69.4"	"6.39"	"907.42"	"4.70"	"3"	"2"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"58.7"	"49.7"	"172.3"	"47.0"	"52.3"	"54.2"	"202.4"	"40.0"	"70.3"	"51.3"	"48.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P2I0"	"Cleavage and polyadenylation specificity factor subunit 2 OS=Homo sapiens OX=9606 GN=CPSF2 PE=1 SV=2"	"4"	"1"	"1"	"1"	"782"	"88.4"	"5.11"	""	"4.70"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf07521, Pf10996, Pf13299, Pf16661"	"53981"	"ENSG00000165934"	"CPSF2"	"B3KME1; hsa:53981; Q6NSJ1; Q9H3W7; Q9P2I0"	"Transport of Mature mRNA Derived from an Intronless Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"mRNA processing"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9ULR0"	"Pre-mRNA-splicing factor ISY1 homolog OS=Homo sapiens OX=9606 GN=ISY1 PE=1 SV=3"	"7"	"1"	"2"	"1"	"285"	"33.0"	"5.17"	"491.86"	"4.70"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf06246"	"100534599; 57461"	"ENSG00000240682"	"ISY1"	"hsa:100534599; hsa:57461; Q96IL2; Q9BT05; Q9ULR0"	"Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; mRNA Splicing - Major Pathway"	""	"5"	"0"	"6.8"	"8.9"	"29.6"	"9.3"	"5.4"	"8.6"	"29.0"	"2.7"	"6.3"	"3.3"	"5.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6YN16"	"Hydroxysteroid dehydrogenase-like protein 2 OS=Homo sapiens OX=9606 GN=HSDL2 PE=1 SV=1"	"4"	"1"	"2"	"1"	"418"	"45.4"	"7.99"	"522.70"	"4.70"	"1"	"1"	""	"mitochondrion;other cytoplasmic organelle"	"other molecular function"	"Pf00106, Pf02036"	"84263"	"ENSG00000119471"	"HSDL2"	"A8K1L4; A8K8X1; A8MSV3; hsa:84263; Q658M8; Q6YN16; Q9BT58"	""	""	"0"	"0"	"28.3"	"36.9"	"146.1"	"33.8"	"29.4"	"22.5"	"145.6"	"9.7"	"20.3"	"18.0"	"16.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19174"	"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 OS=Homo sapiens OX=9606 GN=PLCG1 PE=1 SV=1"	"2"	"1"	"2"	"1"	"1290"	"148.4"	"6.05"	"546.32"	"4.70"	"1"	"1"	"other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00017, Pf00018, Pf00168, Pf00387, Pf00388"	"5335"	"ENSG00000124181"	"PLCG1"	"B7ZLY7; B9EGH4; E1P5W4; hsa:5335; P19174; Q2V575"	"ISG15 antiviral mechanism; Role of phospholipids in phagocytosis; FCERI mediated MAPK activation; FCERI mediated Ca+2 mobilization; FCGR3A-mediated IL10 synthesis; Generation of second messenger molecules; Signaling by ALK fusions and activated point mutants; RET signaling; Downstream signal transduction; Signaling by ALK; DAP12 signaling; Signaling by ERBB2 KD Mutants; Signaling by ERBB2 TMD/JMD mutants; EGFR interacts with phospholipase C-gamma; Signaling by FGFR1 in disease; Synthesis of IP3 and IP4 in the cytosol; Phospholipase C-mediated cascade: FGFR1; Phospholipase C-mediated cascade; FGFR2; Signaling by FGFR2 in disease; VEGFR2 mediated cell proliferation; Phospholipase C-mediated cascade; FGFR3; Phospholipase C-mediated cascade; FGFR4; Signaling by FGFR3 in disease; DAG and IP3 signaling; Erythropoietin activates Phospholipase C gamma (PLCG); Role of second messengers in netrin-1 signaling; Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; PLCG1 events in ERBB2 signaling; Constitutive Signaling by EGFRvIII; Signaling by ERBB2 ECD mutants; Signaling by FGFR4 in disease; PLC-gamma1 signalling; PECAM1 interactions; Activated NTRK2 signals through PLCG1; Activated NTRK3 signals through PLCG1"	"Angiogenesis; IL-1 signaling pathway; RANKL/RANK signaling pathway; Leptin signaling pathway; Glioblastoma signaling pathways; B cell receptor signaling pathway; Corticotropin-releasing hormone signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; PDGF pathway; Primary focal segmental glomerulosclerosis (FSGS); T cell receptor and co-stimulatory signaling; Myometrial relaxation and contraction pathways; Kit receptor signaling pathway; MFAP5-mediated ovarian cancer cell motility and invasiveness; BDNF-TrkB signaling; Physico-chemical features and toxicity-associated pathways; T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection; VEGFA-VEGFR2 signaling; GPR40 pathway; Ras signaling; Non-small cell lung cancer; EGF/EGFR signaling pathway; Resistin as a regulator of inflammation; Fragile X syndrome; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Gastrin signaling pathway; IL-18 signaling pathway; EGFR tyrosine kinase inhibitor resistance; mBDNF and proBDNF regulation of GABA neurotransmission; Modulators of TCR signaling and T cell activation; CCL18 signaling pathway; Th17 cell differentiation pathway; GDNF signaling; A network map of Macrophage-stimulating protein (MSP) signaling; ErbB signaling pathway; T-cell receptor signaling pathway"	"71"	"0"	"26.1"	"33.7"	"125.9"	"39.6"	"33.8"	"28.1"	"140.0"	"19.4"	"30.2"	"20.3"	"27.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96CP2"	"FLYWCH family member 2 OS=Homo sapiens OX=9606 GN=FLYWCH2 PE=1 SV=1"	"14"	"1"	"2"	"1"	"140"	"14.6"	"8.46"	"450.92"	"4.69"	"1"	"1"	""	""	""	"Pf15423"	"114984"	"ENSG00000162076"	"FLYWCH2"	"hsa:114984; Q96CP2"	""	""	"0"	"0"	"46.4"	"44.9"	"133.0"	"46.8"	"58.6"	"49.0"	"184.8"	"35.3"	"74.3"	"80.3"	"94.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P56211"	"cAMP-regulated phosphoprotein 19 OS=Homo sapiens OX=9606 GN=ARPP19 PE=1 SV=2"	"23"	"1"	"1"	"1"	"112"	"12.3"	"9.09"	""	"4.69"	""	"1"	"cell cycle OR cell proliferation;other biological processes"	"nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf04667"	"10776"	"ENSG00000128989"	"ARPP19"	"B2R497; hsa:10776; P56211; Q6IAM2; Q86TA6; Q9UD70"	"MASTL Facilitates Mitotic Progression"	""	"1"	"0"	"16.6"	"14.8"	"48.1"	"18.3"	"16.7"	"16.6"	"107.7"	"24.6"	"43.3"	"29.0"	"46.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UPU5"	"Ubiquitin carboxyl-terminal hydrolase 24 OS=Homo sapiens OX=9606 GN=USP24 PE=1 SV=3"	"1"	"3"	"5"	"2"	"2620"	"294.2"	"6.14"	"791.49"	"4.69"	"3"	"2"	"protein metabolism;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf00443, Pf12030"	"23358"	"ENSG00000162402"	"USP24"	"hsa:23358; Q6ZSY2; Q8N2Y4; Q9NXD1; Q9UPU5"	"Ub-specific processing proteases"	""	"1"	"0"	"28.4"	"35.8"	"127.3"	"27.1"	"26.3"	"18.9"	"166.2"	"35.0"	"43.6"	"33.2"	"33.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BTZ2"	"Dehydrogenase/reductase SDR family member 4 OS=Homo sapiens OX=9606 GN=DHRS4 PE=1 SV=3"	"5"	"1"	"2"	"1"	"278"	"29.5"	"8.56"	"590.15"	"4.69"	"1"	"1"	"other metabolic processes;other biological processes"	"other membranes;cytosol;mitochondrion;ER/Golgi;nucleus;other cytoplasmic organelle"	"other molecular function"	"Pf13561"	"10901"	"ENSG00000157326; ENSG00000284807"	"DHRS4"	"B2RB10; B7WNS9; D3YTB8; E2QRL8; hsa:10901; O95162; Q20CR0; Q2LC19; Q2LE81; Q58IU4; Q6E0Y1; Q6UWU3; Q71UQ6; Q8TD03; Q9BTZ2; Q9H3N5; Q9NV08"	"Peroxisomal protein import; RA biosynthesis pathway"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04899"	"Guanine nucleotide-binding protein G(i) subunit alpha-2 OS=Homo sapiens OX=9606 GN=GNAI2 PE=1 SV=3"	"5"	"2"	"3"	"2"	"355"	"40.4"	"5.54"	"267.56"	"4.68"	"1"	"2"	"cell-cell signaling;cell cycle OR cell proliferation;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00503"	"2771"	"ENSG00000114353"	"GNAI2"	"B3KTZ0; B4DYA0; B4E2X5; hsa:2771; P04899; Q6B6N3; Q8IZ71"	"G alpha (i) signalling events; G alpha (z) signalling events; Adenylate cyclase inhibitory pathway; ADP signalling through P2Y purinoceptor 12; Extra-nuclear estrogen signaling; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production; Adrenaline,noradrenaline inhibits insulin secretion"	"Thyroid stimulating hormone (TSH) signaling pathway; Corticotropin-releasing hormone signaling pathway; S1P receptor signal transduction; Complement system; G protein signaling pathways; Chemokine signaling pathway; Hippo signaling regulation pathways; Purinergic signaling; Opioid receptor pathways; Calcium regulation in cardiac cells; Serotonin HTR1 group and FOS pathway"	"21"	"0"	"161.8"	"167.8"	"407.6"	"172.7"	"158.7"	"155.9"	"488.1"	"172.8"	"442.1"	"419.8"	"404.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75569"	"Interferon-inducible double-stranded RNA-dependent protein kinase activator A OS=Homo sapiens OX=9606 GN=PRKRA PE=1 SV=1"	"3"	"1"	"4"	"1"	"313"	"34.4"	"8.41"	"478.50"	"4.67"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00035"	"8575"	"ENSG00000180228"	"PRKRA"	"A8K3I6; hsa:8575; O75569; Q53G24; Q6X7T5; Q8NDK4"	"MicroRNA (miRNA) biogenesis; Small interfering RNA (siRNA) biogenesis"	"VEGFA-VEGFR2 signaling; Ebola virus infection in host"	"4"	"0"	"19.8"	"23.6"	"70.2"	"18.7"	"19.2"	"19.7"	"75.5"	"8.2"	"13.4"	"8.5"	"4.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H0S4"	"Probable ATP-dependent RNA helicase DDX47 OS=Homo sapiens OX=9606 GN=DDX47 PE=1 SV=1"	"7"	"2"	"3"	"2"	"455"	"50.6"	"9.10"	"846.37"	"4.67"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes;signal transduction"	"nucleus"	"other molecular function"	"Pf00270, Pf00271"	"51202"	"ENSG00000213782"	"DDX47"	"B3KXP4; G5E955; hsa:51202; Q96GM0; Q96NV8; Q9H0S4; Q9UI98"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	"7.0"	"7.3"	"34.1"	"8.0"	"9.0"	"6.0"	"28.9"	"5.7"	"6.7"	"5.2"	"6.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H4L7"	"SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 OS=Homo sapiens OX=9606 GN=SMARCAD1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"1026"	"117.3"	"5.55"	"616.07"	"4.67"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271"	"56916"	"ENSG00000163104"	"SMARCAD1"	"B7Z799; hsa:56916; Q05D56; Q96SX1; Q9H017; Q9H4L7; Q9H860; Q9NPU9; Q9ULU7"	""	""	"0"	"0"	"54.1"	"70.1"	"229.6"	"56.0"	"54.4"	"45.5"	"201.6"	"14.6"	"21.9"	"18.6"	"17.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86SX6"	"Glutaredoxin-related protein 5, mitochondrial OS=Homo sapiens OX=9606 GN=GLRX5 PE=1 SV=2"	"11"	"2"	"5"	"2"	"157"	"16.6"	"6.79"	"778.86"	"4.66"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00462"	"51218"	"ENSG00000182512"	"GLRX5"	"hsa:51218; Q0X088; Q3YML0; Q86SX6; Q86WY3; Q8IZ54"	"Mitochondrial iron-sulfur cluster biogenesis"	"Iron-sulfur cluster biogenesis"	"2"	"0"	"82.6"	"131.2"	"448.0"	"99.7"	"101.7"	"121.0"	"543.7"	"92.9"	"114.4"	"96.6"	"138.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3D7"	"Mitochondrial import inner membrane translocase subunit TIM16 OS=Homo sapiens OX=9606 GN=PAM16 PE=1 SV=2"	"16"	"2"	"4"	"2"	"125"	"13.8"	"9.70"	"535.47"	"4.66"	"2"	"2"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion;other cell component"	""	"Pf03656"	"51025"	"ENSG00000217930; ENSG00000282228"	"PAM16"	"hsa:51025; Q6I9Z3; Q9H5X3; Q9Y3D7"	"Mitochondrial protein import"	""	"1"	"0"	"50.2"	"50.1"	"178.9"	"48.6"	"38.0"	"39.1"	"177.8"	"27.0"	"39.6"	"37.2"	"26.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96QK1"	"Vacuolar protein sorting-associated protein 35 OS=Homo sapiens OX=9606 GN=VPS35 PE=1 SV=2"	"2"	"1"	"2"	"1"	"796"	"91.6"	"5.49"	"488.42"	"4.66"	"1"	"1"	"cell-cell signaling;cell organization and biogenesis;transport;signal transduction;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding"	"Pf03635"	"55737"	"ENSG00000069329"	"VPS35"	"hsa:55737; Q561W2; Q96QK1; Q9H016; Q9H096; Q9H4P3; Q9H8J0; Q9NRS7; Q9NVG2; Q9NX80; Q9NZK2"	"WNT ligand biogenesis and trafficking"	""	"1"	"0"	"6.6"	"15.6"	"28.4"	"4.1"	"5.0"	"4.3"	"26.4"	"13.8"	"9.6"	"3.2"	"5.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7RTV0"	"PHD finger-like domain-containing protein 5A OS=Homo sapiens OX=9606 GN=PHF5A PE=1 SV=1"	"14"	"2"	"4"	"2"	"110"	"12.4"	"8.41"	"547.99"	"4.66"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03660"	"84844"	"ENSG00000100410"	"PHF5A"	"hsa:84844; Q7RTV0; Q9UH06"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"0"	"251.6"	"255.3"	"744.1"	"241.2"	"251.7"	"220.2"	"802.2"	"117.8"	"201.5"	"168.1"	"187.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y6W5"	"Wiskott-Aldrich syndrome protein family member 2 OS=Homo sapiens OX=9606 GN=WASF2 PE=1 SV=3"	"3"	"1"	"2"	"1"	"498"	"54.3"	"5.53"	"617.19"	"4.65"	"1"	"1"	"cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02205"	"10163"	"ENSG00000158195"	"WASF2"	"B4DZN0; hsa:10163; O60794; Q9UDY7; Q9Y6W5"	"RAC1 GTPase cycle; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; RAC2 GTPase cycle; RAC3 GTPase cycle; VEGFA-VEGFR2 Pathway"	"Regulation of actin cytoskeleton"	"8"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NR09"	"Baculoviral IAP repeat-containing protein 6 OS=Homo sapiens OX=9606 GN=BIRC6 PE=1 SV=2"	"0"	"2"	"3"	"2"	"4857"	"529.9"	"6.05"	"384.57"	"4.65"	"1"	"2"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"17.5"	"18.8"	"55.4"	"15.0"	"13.5"	"8.6"	"58.3"	"7.9"	"8.6"	"5.8"	"5.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P37108"	"Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2"	"16"	"4"	"5"	"4"	"136"	"14.6"	"10.04"	"1052.44"	"4.65"	"3"	"2"	"transport"	"non-structural extracellular;cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02290"	"6727"	"ENSG00000140319"	"SRP14"	"B5BUF5; hsa:6727; P37108; Q6B0K5; Q96Q14"	"Neutrophil degranulation; SRP-dependent cotranslational protein targeting to membrane"	""	"2"	"0"	"385.2"	"399.0"	"1578.0"	"339.0"	"254.1"	"246.8"	"1327.3"	"193.0"	"427.6"	"615.0"	"985.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q67FW5"	"UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1 OS=Homo sapiens OX=9606 GN=B3GNTL1 PE=2 SV=2"	"5"	"2"	"4"	"2"	"361"	"40.7"	"7.40"	"533.37"	"4.64"	"2"	"2"	""	""	"other molecular function"	"Pf00535"	"146712"	"ENSG00000175711; ENSG00000277033"	"B3GNTL1"	"hsa:146712; Q67FW5; Q6GV30; Q8WUT3"	"O-linked glycosylation of mucins"	""	"1"	"0"	"11.7"	"8.9"	"21.3"	"11.2"	"8.2"	"9.1"	"46.6"	"27.0"	"114.2"	"195.4"	"291.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60216"	"Double-strand-break repair protein rad21 homolog OS=Homo sapiens OX=9606 GN=RAD21 PE=1 SV=2"	"4"	"1"	"1"	"1"	"631"	"71.6"	"4.65"	""	"4.64"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04824, Pf04825"	"5885"	"ENSG00000164754"	"RAD21"	"A8K0E0; hsa:5885; O60216; Q15001; Q99568"	"Meiotic synapsis; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; SUMOylation of DNA damage response and repair proteins; Estrogen-dependent gene expression; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"Cell cycle; Prion disease pathway; Regulation of sister chromatid separation at the metaphase-anaphase transition; Cohesin complex - Cornelia de Lange syndrome; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome"	"12"	"0"	"10.5"	"13.8"	"36.8"	"12.5"	"12.5"	"9.9"	"28.4"	"7.6"	"7.0"	"10.1"	"7.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BYG3"	"MKI67 FHA domain-interacting nucleolar phosphoprotein OS=Homo sapiens OX=9606 GN=NIFK PE=1 SV=1"	"11"	"2"	"3"	"2"	"293"	"34.2"	"9.88"	"813.03"	"4.63"	"2"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf12196"	"84365"	"ENSG00000155438"	"NIFK"	"A8K788; hsa:84365; Q8TB66; Q96ED4; Q9BYG3"	""	""	"0"	"0"	"30.6"	"33.9"	"101.7"	"29.0"	"27.7"	"25.3"	"133.7"	"22.1"	"34.6"	"20.7"	"30.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WYQ5"	"Microprocessor complex subunit DGCR8 OS=Homo sapiens OX=9606 GN=DGCR8 PE=1 SV=1"	"4"	"2"	"4"	"2"	"773"	"86.0"	"5.95"	"596.81"	"4.61"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00035"	"54487"	"ENSG00000128191"	"DGCR8"	"B2R8G1; hsa:54487; Q6DCB2; Q6MZE9; Q6Y2L0; Q8WYQ5; Q96G39; Q96GP8; Q9H6L8; Q9H6T7; Q9NRW2"	"Transcriptional Regulation by MECP2; MicroRNA (miRNA) biogenesis"	"miRNA biogenesis; exRNA mechanism of action and biogenesis; DDX1 as a regulatory component of the Drosha microprocessor; 22q11.2 copy number variation syndrome"	"6"	"0"	"35.9"	"26.6"	"101.9"	"28.1"	"28.1"	"25.9"	"108.8"	"16.6"	"24.8"	"23.5"	"26.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14738"	"Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform OS=Homo sapiens OX=9606 GN=PPP2R5D PE=1 SV=1"	"3"	"2"	"4"	"1"	"602"	"69.9"	"8.13"	"505.41"	"4.61"	"2"	"2"	"protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf01603"	"5528"	"ENSG00000112640"	"PPP2R5D"	"A8K3I9; B5BUA6; hsa:5528; O00494; O00696; Q14738; Q15171; Q5TC39"	"RAF activation; Negative regulation of MAPK pathway; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Disassembly of the destruction complex and recruitment of AXIN to the membrane; Beta-catenin phosphorylation cascade; Signaling by GSK3beta mutants; CTNNB1 S33 mutants aren't phosphorylated; CTNNB1 S37 mutants aren't phosphorylated; CTNNB1 S45 mutants aren't phosphorylated; CTNNB1 T41 mutants aren't phosphorylated; APC truncation mutants have impaired AXIN binding; AXIN missense mutants destabilize the destruction complex; Truncations of AMER1 destabilize the destruction complex; Regulation of glycolysis by fructose 2,6-bisphosphate metabolism; Platelet sensitization by LDL; CTLA4 inhibitory signaling; DARPP-32 events; PP2A-mediated dephosphorylation of key metabolic factors; ERKs are inactivated"	"Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; 16p11.2 proximal deletion syndrome; Glycogen synthesis and degradation; Cohesin complex - Cornelia de Lange syndrome"	"33"	"0"	"3.2"	"10.3"	"23.0"	"7.3"	"8.0"	"3.6"	"37.1"	"4.6"	"5.6"	"4.6"	"5.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92575"	"UBX domain-containing protein 4 OS=Homo sapiens OX=9606 GN=UBXN4 PE=1 SV=2"	"5"	"2"	"4"	"2"	"508"	"56.7"	"6.38"	"571.10"	"4.58"	"2"	"2"	"protein metabolism;other metabolic processes;stress response"	"other membranes;cytosol;ER/Golgi;nucleus"	""	"Pf00789"	"23190"	"ENSG00000144224"	"UBXN4"	"A8K9W4; hsa:23190; Q4ZG56; Q8IYM5; Q92575"	""	""	"0"	"0"	"138.9"	"156.2"	"518.1"	"157.7"	"148.1"	"131.8"	"518.3"	"63.2"	"108.5"	"71.3"	"60.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P78417"	"Glutathione S-transferase omega-1 OS=Homo sapiens OX=9606 GN=GSTO1 PE=1 SV=2"	"7"	"2"	"4"	"2"	"241"	"27.5"	"6.60"	"635.61"	"4.58"	"2"	"2"	"other metabolic processes;signal transduction;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf13417, Pf14497"	"9446"	"ENSG00000148834"	"GSTO1"	"D3DRA3; F5H7H0; hsa:9446; P78417; Q5TA03; Q7Z3T2"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Glutathione conjugation; Vitamin C (ascorbate) metabolism; Methylation"	"Myometrial relaxation and contraction pathways; Arsenic metabolism and reactive oxygen species generation; Metapathway biotransformation Phase I and II"	"7"	"0"	"108.7"	"127.3"	"693.8"	"135.5"	"135.5"	"86.9"	"837.3"	"78.0"	"135.7"	"147.3"	"180.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06850"	"Corticoliberin OS=Homo sapiens OX=9606 GN=CRH PE=1 SV=1"	"7"	"1"	"2"	"1"	"196"	"21.4"	"9.96"	""	"4.57"	""	"1"	"cell-cell signaling;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;other cell component"	"signal transduction activity or receptor binding"	"Pf00473"	"1392"	"ENSG00000147571"	"CRH"	"B3KQS4; hsa:1392; P06850"	"G alpha (s) signalling events; Class B/2 (Secretin family receptors); MECP2 regulates transcription of neuronal ligands"	"Corticotropin-releasing hormone signaling pathway; Myometrial relaxation and contraction pathways; Serotonin and anxiety-related events; Serotonin and anxiety; Orexin receptor pathway"	"8"	"0"	"117.0"	"136.7"	"178.2"	"109.0"	"137.1"	"127.0"	"192.9"	"86.5"	"119.2"	"92.5"	"102.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96P47"	"Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 OS=Homo sapiens OX=9606 GN=AGAP3 PE=1 SV=2"	"1"	"1"	"4"	"1"	"875"	"95.0"	"7.97"	"604.79"	"4.55"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00071, Pf01412, Pf12796"	"116988"	"ENSG00000133612"	"AGAP3"	"B3KNZ8; E9PAL8; hsa:116988; Q59EN0; Q96P47; Q96RK3"	""	""	"0"	"0"	"16.6"	"14.0"	"19.8"	"5.6"	"10.6"	"8.5"	"25.0"	"9.3"	"37.8"	"72.8"	"99.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86TS9"	"39S ribosomal protein L52, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL52 PE=1 SV=2"	"22"	"3"	"4"	"3"	"123"	"13.7"	"10.26"	"1075.30"	"4.55"	"3"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf18699"	"122704"	"ENSG00000172590"	"MRPL52"	"A6NMQ8; A8MXK5; A8MYI6; G3XCN9; hsa:122704; Q6NVH8; Q86TS9"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"222.8"	"182.2"	"590.5"	"203.6"	"200.0"	"223.6"	"752.3"	"131.7"	"239.2"	"202.3"	"174.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75934"	"Pre-mRNA-splicing factor SPF27 OS=Homo sapiens OX=9606 GN=BCAS2 PE=1 SV=1"	"6"	"1"	"2"	"1"	"225"	"26.1"	"5.66"	"421.08"	"4.54"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytoskeleton;nucleus;other cell component"	""	"Pf05700"	"10286"	"ENSG00000116752"	"BCAS2"	"hsa:10286; O75934; Q6FGS0"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"44.9"	"52.1"	"173.6"	"43.9"	"46.8"	"37.7"	"171.7"	"21.1"	"55.0"	"73.5"	"136.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5K6"	"CD2-associated protein OS=Homo sapiens OX=9606 GN=CD2AP PE=1 SV=1"	"4"	"2"	"4"	"2"	"639"	"71.4"	"6.40"	"533.49"	"4.54"	"2"	"2"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00018, Pf14604"	"23607"	"ENSG00000198087"	"CD2AP"	"A6NL34; hsa:23607; Q5VYA3; Q9UG97; Q9Y5K6"	"Nephrin family interactions"	"Primary focal segmental glomerulosclerosis (FSGS); Nephrotic syndrome; Genes controlling nephrogenesis; GDNF signaling"	"5"	"0"	"29.5"	"31.6"	"113.8"	"28.2"	"31.9"	"19.4"	"90.5"	"16.2"	"25.4"	"14.5"	"16.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08133"	"Annexin A6 OS=Homo sapiens OX=9606 GN=ANXA6 PE=1 SV=3"	"4"	"3"	"5"	"3"	"673"	"75.8"	"5.60"	"894.62"	"4.53"	"3"	"2"	"cell organization and biogenesis;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;mitochondrion;other cytoplasmic organelle;other cell component"	"transporter activity;cytoskeletal activity;other molecular function"	"Pf00191"	"309"	"ENSG00000197043"	"ANXA6"	"B7Z8A7; D3DQH4; E9PGK1; hsa:309; P08133; Q6ZT79"	"Smooth Muscle Contraction"	"Calcium regulation in cardiac cells; Prostaglandin synthesis and regulation"	"3"	"0"	"24.7"	"25.2"	"90.5"	"22.8"	"19.5"	"19.1"	"92.9"	"16.6"	"27.6"	"57.2"	"144.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BVS4"	"Serine/threonine-protein kinase RIO2 OS=Homo sapiens OX=9606 GN=RIOK2 PE=1 SV=2"	"3"	"1"	"2"	"1"	"552"	"63.2"	"5.94"	"263.38"	"4.52"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf01163, Pf09202"	"55781"	"ENSG00000058729"	"RIOK2"	"D6RDI3; hsa:55781; Q9BVS4; Q9NUT0"	"Major pathway of rRNA processing in the nucleolus and cytosol"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NVM6"	"DnaJ homolog subfamily C member 17 OS=Homo sapiens OX=9606 GN=DNAJC17 PE=1 SV=1"	"6"	"1"	"2"	"1"	"304"	"34.7"	"8.53"	"496.44"	"4.52"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf00226"	"55192"	"ENSG00000104129"	"DNAJC17"	"hsa:55192; Q9NVM6"	""	""	"0"	"0"	"7.2"	"6.4"	"30.4"	"9.4"	"5.0"	"4.8"	"34.7"	"3.7"	"20.6"	"42.0"	"61.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q00403"	"Transcription initiation factor IIB OS=Homo sapiens OX=9606 GN=GTF2B PE=1 SV=1"	"5"	"1"	"2"	"1"	"316"	"34.8"	"8.35"	"452.42"	"4.52"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00382, Pf08271"	"2959"	"ENSG00000137947"	"GTF2B"	"A8K1A7; hsa:2959; Q00403; Q5JS30"	"RNA Polymerase II Pre-transcription Events; RNA polymerase II transcribes snRNA genes; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation"	"Eukaryotic transcription initiation"	"10"	"0"	"4.9"	"7.1"	"29.2"	"4.2"	"8.0"	"4.3"	"30.4"	"2.9"	"9.9"	"10.6"	"30.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46939"	"Utrophin OS=Homo sapiens OX=9606 GN=UTRN PE=1 SV=2"	"1"	"2"	"4"	"2"	"3433"	"394.2"	"5.33"	"594.52"	"4.51"	"2"	"1"	"cell-cell signaling;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00307, Pf00435, Pf00569, Pf09068, Pf09069"	"7402"	"ENSG00000152818"	"UTRN"	"hsa:7402; P46939; Q5SYY1; Q5SZ57; Q9UJ40"	"EGR2 and SOX10-mediated initiation of Schwann cell myelination"	"Primary focal segmental glomerulosclerosis (FSGS)"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q15058"	"Kinesin-like protein KIF14 OS=Homo sapiens OX=9606 GN=KIF14 PE=1 SV=1"	"1"	"2"	"4"	"2"	"1648"	"186.4"	"7.91"	"553.10"	"4.50"	"2"	"2"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225, Pf00498, Pf16183"	"9928"	"ENSG00000118193"	"KIF14"	"hsa:9928; Q14CI8; Q15058; Q4G0A5; Q5T1W3"	"RND2 GTPase cycle; RND1 GTPase cycle; RHO GTPases activate CIT"	""	"3"	"0"	"162.8"	"178.0"	"540.3"	"177.6"	"185.6"	"165.4"	"735.1"	"333.3"	"941.8"	"872.7"	"892.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NWU1"	"3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial OS=Homo sapiens OX=9606 GN=OXSM PE=1 SV=1"	"3"	"1"	"2"	"1"	"459"	"48.8"	"7.66"	"399.51"	"4.48"	"1"	"1"	"other metabolic processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf00109, Pf02801"	"54995"	"ENSG00000151093"	"OXSM"	"hsa:54995; Q9NWU1"	""	"Mitochondrial fatty acid synthesis pathway"	"1"	"0"	"13.9"	"16.4"	"47.5"	"19.4"	"18.1"	"10.9"	"75.1"	"24.1"	"89.9"	"162.9"	"301.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O77932"	"Decapping and exoribonuclease protein OS=Homo sapiens OX=9606 GN=DXO PE=2 SV=2"	"6"	"1"	"1"	"1"	"396"	"44.9"	"7.69"	""	"4.48"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf08652"	"1797"	"ENSG00000204348; ENSG00000206346; ENSG00000224313; ENSG00000225682; ENSG00000234798; ENSG00000236765"	"DXO"	"A2CER3; B0UZ80; hsa:1797; O15004; O77932; O78127; O78128; Q5ST60; Q6IPZ2; Q9NPK4"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HAU5"	"Regulator of nonsense transcripts 2 OS=Homo sapiens OX=9606 GN=UPF2 PE=1 SV=1"	"2"	"3"	"4"	"2"	"1272"	"147.7"	"5.69"	"569.24"	"4.48"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02854, Pf04050"	"26019"	"ENSG00000151461"	"UPF2"	"A6NLJ5; D3DRS0; hsa:26019; Q14BM1; Q5W0J4; Q8N8U1; Q9H1J2; Q9HAU5; Q9NWL1; Q9P2D9; Q9Y4M9"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	""	"2"	"0"	"130.7"	"120.5"	"223.3"	"125.4"	"140.8"	"118.7"	"256.7"	"99.7"	"152.1"	"118.6"	"110.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BZX2"	"Uridine-cytidine kinase 2 OS=Homo sapiens OX=9606 GN=UCK2 PE=1 SV=1"	"7"	"1"	"2"	"1"	"261"	"29.3"	"6.70"	"531.87"	"4.46"	"1"	"1"	"other metabolic processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00485"	"7371"	"ENSG00000143179"	"UCK2"	"hsa:7371; Q5VV91; Q7KZV3; Q92528; Q96KG5; Q9BU42; Q9BZX2"	"Pyrimidine salvage"	"Fluoropyrimidine activity; Pyrimidine metabolism"	"3"	"0"	"23.8"	"22.8"	"127.6"	"24.1"	"17.5"	"11.5"	"128.8"	"13.4"	"15.3"	"5.3"	"12.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IWF6"	"Protein DENND6A OS=Homo sapiens OX=9606 GN=DENND6A PE=1 SV=1"	"2"	"1"	"2"	"1"	"608"	"69.5"	"8.27"	"593.73"	"4.46"	"1"	"1"	"other biological processes"	"cytosol;other cytoplasmic organelle;other cell component"	"enzyme regulator activity"	"Pf08616, Pf09794"	"201627"	"ENSG00000174839"	"DENND6A"	"hsa:201627; Q7Z5T4; Q8IWF6; Q8N235; Q8TEG8"	"RAB GEFs exchange GTP for GDP on RABs"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P98175"	"RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3"	"2"	"1"	"2"	"1"	"930"	"103.5"	"5.97"	"500.75"	"4.46"	"1"	"1"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00641, Pf01585, Pf17780"	"8241"	"ENSG00000182872"	"RBM10"	"A0A0A0MR66; C4AM81; hsa:8241; P98175; Q14136; Q5JRR2; Q9BTE4; Q9BTX0; Q9NTB1"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	""	"2"	"0"	"41.7"	"51.4"	"157.1"	"48.6"	"50.9"	"39.4"	"178.0"	"36.2"	"46.5"	"37.4"	"43.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BRX8"	"Peroxiredoxin-like 2A OS=Homo sapiens OX=9606 GN=PRXL2A PE=1 SV=3"	"5"	"1"	"4"	"1"	"229"	"25.7"	"8.84"	"585.11"	"4.45"	"1"	"1"	"other biological processes"	"non-structural extracellular;other cell component"	"other molecular function"	"Pf13911"	"84293"	"ENSG00000122378"	"PRXL2A"	"B2RD81; hsa:84293; Q6UW08; Q8N2K3; Q8NBK9; Q96JR0; Q9BRX8"	""	""	"0"	"0"	"12.4"	"12.6"	"50.4"	"8.9"	"8.6"	"7.7"	"50.8"	"7.4"	"7.4"	"5.2"	"0.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"O60493"	"Sorting nexin-3 OS=Homo sapiens OX=9606 GN=SNX3 PE=1 SV=3"	"12"	"1"	"2"	"1"	"162"	"18.8"	"8.66"	"416.74"	"4.45"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00787"	"8724"	"ENSG00000112335"	"SNX3"	"A8K0B1; E1P5E4; E1P5E5; hsa:8724; O60493; O60718; Q4TT29; Q4TT31; Q5JXJ7; Q5JXJ8; Q96AP9; Q9C0J5; Q9NU45"	"Ub-specific processing proteases; WNT ligand biogenesis and trafficking"	""	"2"	"0"	"12.1"	"9.2"	"58.3"	"12.9"	"8.0"	"4.2"	"78.1"	"2.6"	"11.1"	"3.3"	"4.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NB46"	"Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C OS=Homo sapiens OX=9606 GN=ANKRD52 PE=1 SV=3"	"4"	"3"	"4"	"2"	"1076"	"115.0"	"6.48"	"640.83"	"4.45"	"2"	"2"	""	""	""	"Pf00023, Pf12796"	"283373"	"ENSG00000139645"	"ANKRD52"	"A6NE79; B1Q2K2; hsa:283373; Q8NB46"	""	""	"0"	"1"	"7.8"	"13.9"	"52.7"	"15.3"	"13.3"	"10.2"	"35.5"	"8.2"	"10.4"	"14.0"	"13.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NQW7"	"Xaa-Pro aminopeptidase 1 OS=Homo sapiens OX=9606 GN=XPNPEP1 PE=1 SV=3"	"4"	"2"	"3"	"2"	"623"	"69.9"	"5.67"	"741.41"	"4.45"	"2"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00557, Pf01321, Pf16188, Pf16189"	"7511"	"ENSG00000108039"	"XPNPEP1"	"A8K071; G5E9Y2; G8JLB2; hsa:7511; O15250; Q53EX6; Q8N3Q0; Q96D23; Q9NQW7"	""	""	"0"	"0"	"47.5"	"55.3"	"192.3"	"40.7"	"49.8"	"36.1"	"272.0"	"52.9"	"53.3"	"34.3"	"31.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49590"	"Histidine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=HARS2 PE=1 SV=1"	"6"	"3"	"5"	"1"	"506"	"56.9"	"8.24"	"840.29"	"4.44"	"3"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf03129, Pf13393"	"23438"	"ENSG00000112855"	"HARS2"	"B4DDY8; hsa:23438; P49590"	"Mitochondrial tRNA aminoacylation"	"Primary ovarian insufficiency"	"2"	"0"	"9.0"	"12.3"	"38.6"	"13.0"	"11.1"	"6.4"	"34.6"	"7.9"	"14.1"	"16.2"	"24.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96KP4"	"Cytosolic non-specific dipeptidase OS=Homo sapiens OX=9606 GN=CNDP2 PE=1 SV=2"	"4"	"1"	"2"	"1"	"475"	"52.8"	"5.97"	"715.23"	"4.42"	"1"	"1"	"protein metabolism"	"cytosol;nucleus"	"other molecular function"	"Pf01546, Pf07687"	"55748"	"ENSG00000133313"	"CNDP2"	"B3KUG4; hsa:55748; Q8WY59; Q96KP4; Q9BQ94; Q9NVB4; V9HWE5"	"Glutathione synthesis and recycling; Paracetamol ADME"	""	"2"	"0"	"6.2"	"12.2"	"69.6"	"15.1"	"20.3"	"12.7"	"86.0"	"8.3"	"13.7"	"4.6"	"4.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q63HQ0"	"AP-1 complex-associated regulatory protein OS=Homo sapiens OX=9606 GN=AP1AR PE=1 SV=1"	"4"	"1"	"2"	"1"	"302"	"34.3"	"4.87"	"538.23"	"4.42"	"1"	"1"	"cell adhesion;transport;other biological processes"	"cytosol;ER/Golgi;other cytoplasmic organelle"	"cytoskeletal activity;other molecular function"	"Pf15745"	"55435"	"ENSG00000138660"	"AP1AR"	"B2RCV7; hsa:55435; Q63HQ0; Q96GG6; Q9H0V0; Q9P1L4"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H223"	"EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1"	"4"	"2"	"3"	"1"	"541"	"61.1"	"6.76"	"241.92"	"4.40"	"1"	"2"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00350, Pf12763, Pf16880, Pf18150"	"30844"	"ENSG00000103966"	"EHD4"	"hsa:30844; Q9H223; Q9HAR1; Q9NZN2"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15654"	"Thyroid receptor-interacting protein 6 OS=Homo sapiens OX=9606 GN=TRIP6 PE=1 SV=3"	"4"	"1"	"2"	"1"	"476"	"50.3"	"7.37"	"486.72"	"4.39"	"1"	"1"	"cell adhesion;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00412"	"7205"	"ENSG00000087077"	"TRIP6"	"A4D2E7; F2ZC07; F2ZC08; hsa:7205; O15170; O15275; Q15654; Q9BTB2; Q9BUE5; Q9BXP3; Q9UNT4"	""	""	"0"	"0"	"49.6"	"45.9"	"92.0"	"52.7"	"50.0"	"45.3"	"100.4"	"25.1"	"42.4"	"37.1"	"28.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H1K1"	"Iron-sulfur cluster assembly enzyme ISCU, mitochondrial OS=Homo sapiens OX=9606 GN=ISCU PE=1 SV=2"	"10"	"2"	"2"	"2"	"167"	"18.0"	"9.48"	""	"4.39"	""	"2"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01592"	"23479"	"ENSG00000136003"	"ISCU"	"hsa:23479; Q6P713; Q99617; Q9H1K1; Q9H1K2"	"Maturation of replicase proteins"	"Iron-sulfur cluster biogenesis"	"2"	"0"	"59.7"	"57.5"	"665.8"	"63.5"	"8.3"	"33.6"	"813.5"	"27.2"	"8.1"	"30.4"	"31.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08397"	"Porphobilinogen deaminase OS=Homo sapiens OX=9606 GN=HMBS PE=1 SV=2"	"6"	"1"	"2"	"1"	"361"	"39.3"	"7.18"	"505.35"	"4.39"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf01379, Pf03900"	"3145"	"ENSG00000256269"	"HMBS"	"A8K2L0; G3V1P4; G5EA58; hsa:3145; P08396; P08397; Q16012"	"Heme biosynthesis"	"Hemesynthesis defects and porphyrias; Heme biosynthesis"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"P15927"	"Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2 PE=1 SV=1"	"6"	"1"	"2"	"1"	"270"	"29.2"	"6.15"	"482.90"	"4.39"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf08784"	"6118"	"ENSG00000117748"	"RPA2"	"hsa:6118; P15927; Q52II0; Q5TEI9; Q5TEJ5"	"Fanconi Anemia Pathway; Regulation of HSF1-mediated heat shock response; Regulation of TP53 Activity through Phosphorylation; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Meiotic recombination; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; HSF1 activation; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Removal of the Flap Intermediate; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"miRNA regulation of DNA damage response; Retinoblastoma gene in cancer; G1 to S cell cycle control; DNA replication; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair; DNA damage response"	"38"	"0"	"45.8"	"44.8"	"162.4"	"52.4"	"45.6"	"37.9"	"166.1"	"33.5"	"43.8"	"53.5"	"91.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WU90"	"Zinc finger CCCH domain-containing protein 15 OS=Homo sapiens OX=9606 GN=ZC3H15 PE=1 SV=1"	"3"	"2"	"4"	"2"	"426"	"48.6"	"5.31"	"557.84"	"4.39"	"2"	"2"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00642, Pf16543"	"55854"	"ENSG00000065548"	"ZC3H15"	"B4DMW2; D3DPG7; hsa:55854; Q5QTQ4; Q8WU90; Q8WZ06; Q9NUZ3; Q9NZ37; Q9P079"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"103.4"	"97.2"	"367.0"	"101.1"	"85.8"	"73.8"	"298.3"	"36.1"	"58.6"	"62.8"	"71.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P27361"	"Mitogen-activated protein kinase 3 OS=Homo sapiens OX=9606 GN=MAPK3 PE=1 SV=4"	"4"	"1"	"2"	"1"	"379"	"43.1"	"6.74"	"514.66"	"4.37"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"5595"	"ENSG00000102882"	"MAPK3"	"A8CZ58; B0LPG3; hsa:5595; P27361; Q8NHX1"	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Regulation of PTEN gene transcription; ISG15 antiviral mechanism; Signal transduction by L1; Suppression of apoptosis; Regulation of actin dynamics for phagocytic cup formation; FCERI mediated MAPK activation; FCGR3A-mediated phagocytosis; NPAS4 regulates expression of target genes; RHO GTPases Activate WASPs and WAVEs; Regulation of HSF1-mediated heat shock response; Signaling by BRAF and RAF1 fusions; Thrombin signalling through proteinase activated receptors (PARs); Oxidative Stress Induced Senescence; Signaling by NODAL; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Interferon gamma signaling; Oncogene Induced Senescence; Senescence-Associated Secretory Phenotype (SASP); Growth hormone receptor signaling; Regulation of the apoptosome activity; Estrogen-dependent nuclear events downstream of ESR-membrane signaling; NCAM signaling for neurite out-growth; Downregulation of SMAD2/3:SMAD4 transcriptional activity; RUNX2 regulates osteoblast differentiation; RSK activation; Spry regulation of FGF signaling; MAPK3 (ERK1) activation; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; IFNG signaling activates MAPKs; RNA Polymerase I Promoter Opening; Signaling by Activin; Activation of the AP-1 family of transcription factors; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; Frs2-mediated activation; Signal attenuation; Gastrin-CREB signalling pathway via PKC and MAPK; Nuclear events stimulated by ALK signaling in cancer; ESR-mediated signaling; Negative feedback regulation of MAPK pathway; Advanced glycosylation endproduct receptor signaling; RHO GTPases Activate NADPH Oxidases; ERKs are inactivated; Signaling by MAP2K mutants"	"IL-5 signaling pathway; Osteopontin signaling; MicroRNAs in cardiomyocyte hypertrophy; IL-1 signaling pathway; Thyroxine (thyroid hormone) production; RANKL/RANK signaling pathway; Thyroid stimulating hormone (TSH) signaling pathway; Leptin signaling pathway; Follicle stimulating hormone (FSH) signaling pathway; TNF-related weak inducer of apoptosis (TWEAK) signaling pathway; Prolactin signaling pathway; IL-7 signaling pathway; Alzheimer's disease and miRNA effects; IL-17 signaling pathway; IL-9 signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; Glioblastoma signaling pathways; Androgen receptor network in prostate cancer; TNF-alpha signaling pathway; AGE/RAGE pathway; Interleukin-11 signaling pathway; Corticotropin-releasing hormone signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Spinal cord injury; Alpha 6 beta 4 signaling pathway; PDGF pathway; S1P receptor signal transduction; Common pathways underlying drug addiction; Interleukin-1 (IL-1) structural pathway; Cardiac hypertrophic response; IL-3 signaling pathway; TCA cycle nutrient use and invasiveness of ovarian cancer; Kit receptor signaling pathway; Focal adhesion; Hepatocyte growth factor receptor signaling; MFAP5-mediated ovarian cancer cell motility and invasiveness; RAC1/PAK1/p38/MMP2 pathway; IL6 signaling pathway; Hepatitis C and hepatocellular carcinoma; Hypothesized pathways in pathogenesis of cardiovascular disease; MAPK signaling pathway; T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection; 4-hydroxytamoxifen, dexamethasone, and retinoic acids regulation of p27 expression; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; BMP signaling in eyelid development; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; IL-4 signaling pathway; Prion disease pathway; Endometrial cancer; PI3K-Akt signaling pathway; Chromosomal and microsatellite instability in colorectal cancer ; MAPK cascade; Ras signaling; Epithelial to mesenchymal transition in colorectal cancer; Non-small cell lung cancer; Breast cancer pathway; Pancreatic adenocarcinoma pathway; Acute viral myocarditis; Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells; Neovascularisation processes; Non-genomic actions of 1,25 dihydroxyvitamin D3; Bile acids synthesis and enterohepatic circulation ; Resistin as a regulator of inflammation; Relationship between inflammation, COX-2 and EGFR; Envelope proteins and their potential roles in EDMD physiopathology; Regulatory circuits of the STAT3 signaling pathway; Synaptic signaling pathways associated with autism spectrum disorder; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Translation inhibitors in chronically activated PDGFRA cells; Gastrin signaling pathway; Hepatitis B infection; Melanoma; Netrin-UNC5B signaling pathway; IL-18 signaling pathway; FGFR3 signaling in chondrocyte proliferation and terminal differentiation; Osteoblast differentiation and related diseases; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; TGF-beta receptor signaling in skeletal dysplasias; Kisspeptin/kisspeptin receptor system in the ovary; CAMKK2 pathway; Disruption of postsynaptic signaling by CNV; Host-pathogen interaction of human coronaviruses - MAPK signaling; IL-2 signaling pathway; MAPK pathway in congenital thyroid cancer; 7q11.23 copy number variation syndrome; 16p11.2 proximal deletion syndrome; Neuroinflammation and glutamatergic signaling; Pleural mesothelioma; Orexin receptor pathway; CCL18 signaling pathway; Regulation of actin cytoskeleton; Alzheimer's disease; GDNF signaling; 2q11.2 copy number variation syndrome; Comprehensive IL-17A signaling; Genetic causes of porto-sinusoidal vascular disease; IL-26 signaling pathways; A network map of Macrophage-stimulating protein (MSP) signaling; Role of hypoxia, angiogenesis, and FGF pathway in OA chondrocyte hypertrophy; TGF-beta receptor signaling; EPO receptor signaling; ErbB signaling pathway; T-cell receptor signaling pathway; Serotonin HTR1 group and FOS pathway; Serotonin receptor 2 and ELK-SRF/GATA4 signaling; Serotonin receptor 4/6/7 and NR3C signaling; Toll-like receptor signaling pathway"	"168"	"0"	"58.0"	"69.2"	"219.6"	"67.2"	"76.5"	"56.7"	"270.0"	"49.0"	"74.0"	"64.7"	"66.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16204"	"Coiled-coil domain-containing protein 6 OS=Homo sapiens OX=9606 GN=CCDC6 PE=1 SV=2"	"3"	"2"	"4"	"2"	"474"	"53.3"	"7.34"	"563.22"	"4.35"	"2"	"2"	"cell organization and biogenesis"	"cytosol;cytoskeleton"	"cytoskeletal activity;other molecular function"	"Pf09755"	"8030"	"ENSG00000108091"	"CCDC6"	"hsa:8030; Q15250; Q16204; Q6GSG7"	""	"Retinoblastoma gene in cancer; Mesodermal commitment pathway; 16p11.2 proximal deletion syndrome"	"3"	"0"	"105.1"	"117.6"	"400.2"	"114.8"	"103.6"	"85.5"	"405.4"	"62.0"	"91.1"	"83.3"	"91.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99856"	"AT-rich interactive domain-containing protein 3A OS=Homo sapiens OX=9606 GN=ARID3A PE=1 SV=2"	"4"	"2"	"3"	"2"	"593"	"62.9"	"4.91"	"263.33"	"4.35"	"1"	"2"	"RNA metabolism OR transcription;other biological processes"	"other membranes;cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01388"	"1820"	"ENSG00000116017"	"ARID3A"	"hsa:1820; Q5I858; Q6P9C6; Q8IZA7; Q8N4Z3; Q99856"	"TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest"	""	"1"	"0"	"57.3"	"58.1"	"193.9"	"46.9"	"53.8"	"31.3"	"275.1"	"37.0"	"44.8"	"35.3"	"39.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15149"	"Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3"	"1"	"3"	"5"	"2"	"4684"	"531.5"	"5.96"	"964.99"	"4.32"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00681, Pf03501, Pf17902, Pf18373"	"5339"	"ENSG00000178209"	"PLEC"	"hsa:5339; Q15148; Q15149; Q16640; Q6S376; Q6S377; Q6S378; Q6S379; Q6S380; Q6S381; Q6S382; Q6S383"	"Assembly of collagen fibrils and other multimeric structures; Caspase-mediated cleavage of cytoskeletal proteins; Type I hemidesmosome assembly"	"Envelope proteins and their potential roles in EDMD physiopathology"	"4"	"0"	"87.7"	"80.0"	"235.7"	"90.4"	"57.7"	"60.1"	"156.5"	"23.7"	"48.4"	"49.0"	"40.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5TFE4"	"5'-nucleotidase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=NT5DC1 PE=1 SV=1"	"8"	"2"	"3"	"2"	"455"	"51.8"	"6.35"	"250.43"	"4.32"	"1"	"2"	""	""	"other molecular function"	"Pf05761"	"221294"	"ENSG00000178425"	"NT5DC1"	"B2RND9; B3KR35; hsa:221294; Q5TFE4; Q6XYD5"	""	""	"0"	"0"	"67.4"	"31.5"	"84.6"	"29.1"	"25.6"	"19.3"	"104.4"	"15.8"	"21.4"	"15.7"	"16.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q09666"	"Neuroblast differentiation-associated protein AHNAK OS=Homo sapiens OX=9606 GN=AHNAK PE=1 SV=2"	"3"	"3"	"4"	"3"	"5890"	"628.7"	"6.15"	"238.32"	"4.31"	"1"	"3"	"other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	""	"79026"	"ENSG00000124942"	"AHNAK"	"A1A586; hsa:79026; Q09666"	""	""	"0"	"0"	"189.4"	"201.0"	"505.0"	"171.4"	"182.4"	"156.8"	"603.4"	"172.5"	"302.1"	"360.3"	"611.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQC6"	"Ribosomal protein 63, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL57 PE=1 SV=1"	"13"	"1"	"2"	"1"	"102"	"12.3"	"11.44"	"536.94"	"4.31"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf14978"	"78988"	"ENSG00000173141"	"MRPL57"	"A2A332; hsa:78988; Q9BQC6"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"91.9"	"123.1"	"390.8"	"129.0"	"103.9"	"98.3"	"430.3"	"52.5"	"83.0"	"65.1"	"79.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43491"	"Band 4.1-like protein 2 OS=Homo sapiens OX=9606 GN=EPB41L2 PE=1 SV=1"	"2"	"2"	"4"	"2"	"1005"	"112.5"	"5.44"	"522.09"	"4.29"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf04382, Pf05902, Pf08736, Pf09379, Pf09380"	"2037"	"ENSG00000079819"	"EPB41L2"	"B4DHI8; E9PPD9; hsa:2037; O43491; Q5T4F0; Q68DV2"	"Neurexins and neuroligins"	"Splicing factor NOVA regulated synaptic proteins"	"2"	"0"	"171.6"	"196.3"	"685.1"	"200.9"	"153.0"	"135.9"	"488.9"	"79.9"	"198.4"	"293.3"	"277.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05423"	"DNA-directed RNA polymerase III subunit RPC4 OS=Homo sapiens OX=9606 GN=POLR3D PE=1 SV=2"	"4"	"1"	"2"	"1"	"398"	"44.4"	"6.98"	"591.35"	"4.28"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf05132"	"661"	"ENSG00000168495"	"POLR3D"	"hsa:661; P05423; Q6FI28; Q9BPV7; Q9BPZ1; Q9BXB3"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation"	"Pyrimidine metabolism; Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway"	"10"	"0"	"21.1"	"31.2"	"73.0"	"28.5"	"30.8"	"19.4"	"91.9"	"18.1"	"25.0"	"23.3"	"18.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5JPE7"	"Nodal modulator 2 OS=Homo sapiens OX=9606 GN=NOMO2 PE=1 SV=1"	"2"	"1"	"1"	"1"	"1267"	"139.4"	"5.76"	""	"4.28"	""	"1"	"cell organization and biogenesis"	"other membranes;cytosol;ER/Golgi;other cell component"	"translation activity;other molecular function"	"Pf13620, Pf17802"	"283820"	"ENSG00000185164"	"NOMO2"	"hsa:283820; Q4G177; Q5JPE7"	""	""	"0"	"0"	"35.4"	"41.6"	"151.9"	"35.1"	"32.3"	"19.1"	"159.1"	"17.8"	"34.5"	"17.8"	"15.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00244"	"Copper transport protein ATOX1 OS=Homo sapiens OX=9606 GN=ATOX1 PE=1 SV=1"	"19"	"1"	"2"	"1"	"68"	"7.4"	"7.24"	"465.97"	"4.26"	"1"	"1"	"stress response;transport;other biological processes"	"cytosol"	"other molecular function"	"Pf00403"	"475"	"ENSG00000177556"	"ATOX1"	"A8KAJ8; D3DQI2; hsa:475; O00244; Q2M1R6; Q56AP3"	"Detoxification of Reactive Oxygen Species; Ion influx/efflux at host-pathogen interface"	"Copper homeostasis"	"3"	"0"	"57.2"	"69.2"	"343.9"	"74.8"	"75.7"	"52.9"	"507.2"	"41.8"	"48.7"	"41.6"	"37.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60763"	"General vesicular transport factor p115 OS=Homo sapiens OX=9606 GN=USO1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"962"	"107.8"	"4.91"	"403.58"	"4.25"	"1"	"1"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	""	"Pf04869, Pf04871, Pf18770"	"8615"	"ENSG00000138768"	"USO1"	"B2RAQ0; hsa:8615; O60763; Q6PK63; Q86TB8; Q8N592"	"COPI-mediated anterograde transport; COPII-mediated vesicle transport; Golgi Cisternae Pericentriolar Stack Reorganization"	""	"3"	"0"	"10.1"	"16.7"	"62.3"	"12.1"	"8.8"	"7.5"	"75.3"	"8.9"	"9.0"	"6.2"	"7.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60783"	"28S ribosomal protein S14, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS14 PE=1 SV=1"	"12"	"1"	"2"	"1"	"128"	"15.1"	"11.41"	"498.13"	"4.25"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf00253"	"63931"	"ENSG00000120333"	"MRPS14"	"hsa:63931; O60783; Q5R358"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"31.6"	"31.5"	"99.6"	"30.8"	"45.3"	"25.2"	"112.1"	"24.9"	"29.6"	"28.8"	"20.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NYC9"	"Dynein heavy chain 9, axonemal OS=Homo sapiens OX=9606 GN=DNAH9 PE=1 SV=3"	"0"	"2"	"3"	"1"	"4486"	"511.6"	"5.91"	"251.09"	"4.25"	"1"	"2"	"cell organization and biogenesis;transport;other biological processes"	"non-structural extracellular;cytoskeleton"	"cytoskeletal activity;other molecular function"	"Pf03028, Pf08385, Pf08393, Pf12774, Pf12775, Pf12777, Pf12780, Pf12781, Pf17852, Pf17857, Pf18198, Pf18199"	"1770"	"ENSG00000007174"	"DNAH9"	"A2VCQ8; hsa:1770; O15064; O95494; Q9NQ28; Q9NYC9"	""	""	"0"	"1"	"101.8"	"106.6"	"491.6"	"108.9"	"80.6"	"66.7"	"514.6"	"42.4"	"70.5"	"52.1"	"57.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4Y9"	"U6 snRNA-associated Sm-like protein LSm5 OS=Homo sapiens OX=9606 GN=LSM5 PE=1 SV=3"	"25"	"1"	"1"	"1"	"91"	"9.9"	"4.54"	""	"4.23"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01423"	"23658"	"ENSG00000106355"	"LSM5"	"hsa:23658; Q9Y4Y9"	"mRNA Splicing - Major Pathway; mRNA decay by 5' to 3' exoribonuclease"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15758"	"Neutral amino acid transporter B(0) OS=Homo sapiens OX=9606 GN=SLC1A5 PE=1 SV=2"	"4"	"1"	"2"	"1"	"541"	"56.6"	"5.48"	"422.51"	"4.22"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;other cell component"	"transporter activity;other molecular function"	"Pf00375"	"6510"	"ENSG00000105281"	"SLC1A5"	"A8K9H5; B4DR77; B4DWS4; B7ZB81; D0EYG6; E9PC01; hsa:6510; O95720; Q15758; Q96RL9; Q9BWQ3; Q9UNP2"	"RAC1 GTPase cycle; RHOH GTPase cycle; RHOQ GTPase cycle; RAC3 GTPase cycle; RHOJ GTPase cycle; Amino acid transport across the plasma membrane"	"TYROBP causal network in microglia; mRNA, protein, and metabolite inducation pathway by cyclosporin A; Metabolic reprogramming in colon cancer; Ferroptosis; Amino acid metabolism in triple-negative breast cancer cells"	"11"	"0"	"38.5"	"42.8"	"156.8"	"38.9"	"34.0"	"28.9"	"175.6"	"19.8"	"26.7"	"18.1"	"15.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H6E4"	"Coiled-coil domain-containing protein 134 OS=Homo sapiens OX=9606 GN=CCDC134 PE=1 SV=1"	"7"	"1"	"2"	"1"	"229"	"26.5"	"8.85"	"389.49"	"4.20"	"1"	"1"	"developmental processes;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;nucleus;other cell component"	""	"Pf15002"	"79879"	"ENSG00000100147"	"CCDC134"	"hsa:79879; Q9H6E4"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60551"	"Glycylpeptide N-tetradecanoyltransferase 2 OS=Homo sapiens OX=9606 GN=NMT2 PE=1 SV=1"	"6"	"2"	"3"	"1"	"498"	"56.9"	"7.58"	"708.52"	"4.19"	"2"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf01233, Pf02799"	"9397"	"ENSG00000152465"	"NMT2"	"B0YJ49; hsa:9397; O60551; Q53Y38; Q5VUC8; Q9BRB4"	"Membrane binding and targetting of GAG proteins; Inactivation, recovery and regulation of the phototransduction cascade"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"P48637"	"Glutathione synthetase OS=Homo sapiens OX=9606 GN=GSS PE=1 SV=1"	"5"	"1"	"1"	"1"	"474"	"52.4"	"5.92"	""	"4.17"	""	"1"	"other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol"	"other molecular function"	"Pf03199, Pf03917"	"2937"	"ENSG00000100983"	"GSS"	"B2R697; B6F210; E1P5P9; hsa:2937; P48637; Q4TTD9"	"Glutathione synthesis and recycling; Defective GSS causes GSS deficiency"	"Glutathione metabolism; Trans-sulfuration, one-carbon metabolism and related pathways; Amino acid metabolism; Ferroptosis; Metapathway biotransformation Phase I and II"	"7"	"0"	"25.4"	"24.5"	"80.0"	"23.5"	"26.4"	"16.7"	"85.9"	"21.6"	"26.0"	"22.2"	"19.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z739"	"YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1"	"4"	"2"	"3"	"2"	"585"	"63.8"	"9.04"	"725.63"	"4.17"	"2"	"1"	"cell organization and biogenesis;other biological processes"	"cytosol;other cell component"	"translation activity;nucleic acid binding activity"	"Pf04146"	"253943"	"ENSG00000185728"	"YTHDF3"	"B3KXL4; hsa:253943; Q63Z37; Q659A3; Q7Z739"	""	""	"0"	"0"	"105.8"	"112.3"	"293.1"	"112.6"	"117.1"	"86.8"	"326.5"	"70.6"	"95.7"	"75.9"	"100.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UPW5"	"Cytosolic carboxypeptidase 1 OS=Homo sapiens OX=9606 GN=AGTPBP1 PE=1 SV=3"	"2"	"2"	"4"	"2"	"1226"	"138.4"	"6.15"	"524.91"	"4.16"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00246, Pf18027"	"23287"	"ENSG00000135049"	"AGTPBP1"	"B4DIT6; B4DRZ8; hsa:23287; Q5VV80; Q63HM7; Q658P5; Q6P9D6; Q9H8U6; Q9H9W8; Q9NVK1; Q9UPW5"	"Carboxyterminal post-translational modifications of tubulin"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3D8"	"Adenylate kinase isoenzyme 6 OS=Homo sapiens OX=9606 GN=AK6 PE=1 SV=1"	"9"	"1"	"2"	"1"	"172"	"20.0"	"4.58"	"504.90"	"4.16"	"1"	"1"	"other metabolic processes"	"cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf13238"	"102157402"	"ENSG00000085231; ENSG00000279247"	"AK6"	"A8MSZ6; hsa:102157402; Q5F2S9; Q9Y3D8"	"Interconversion of nucleotide di- and triphosphates"	""	"1"	"0"	"35.5"	"42.1"	"130.8"	"38.3"	"48.1"	"36.1"	"174.3"	"32.7"	"64.3"	"57.3"	"47.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NPH2"	"Inositol-3-phosphate synthase 1 OS=Homo sapiens OX=9606 GN=ISYNA1 PE=1 SV=1"	"3"	"1"	"2"	"1"	"558"	"61.0"	"5.76"	"356.41"	"4.16"	"1"	"1"	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf01658, Pf07994"	"51477"	"ENSG00000105655"	"ISYNA1"	"B3KRT1; G5E9U0; hsa:51477; Q6NXT5; Q7Z525; Q9BT65; Q9H2Y2; Q9NPH2; Q9NSU0; Q9NVW7"	"Synthesis of IP2, IP, and Ins in the cytosol"	""	"1"	"0"	"64.4"	"63.8"	"326.1"	"76.0"	"74.2"	"44.6"	"374.1"	"30.9"	"62.3"	"35.4"	"31.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q08209"	"Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform OS=Homo sapiens OX=9606 GN=PPP3CA PE=1 SV=1"	"2"	"1"	"2"	"1"	"521"	"58.7"	"5.86"	"406.78"	"4.15"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00149"	"5530"	"ENSG00000138814"	"PPP3CA"	"A1A441; A8K3B7; A8W6Z7; A8W6Z8; B5BUA2; hsa:5530; Q08209; Q8TAW9"	"DARPP-32 events; FCERI mediated Ca+2 mobilization; Ca2+ pathway; CLEC7A (Dectin-1) induces NFAT activation; Calcineurin activates NFAT"	"Physiological and pathological hypertrophy of the heart; Energy metabolism; MicroRNAs in cardiomyocyte hypertrophy; Alzheimer's disease and miRNA effects; Spinal cord injury; Amyotrophic lateral sclerosis (ALS); T cell receptor and co-stimulatory signaling; Cardiac hypertrophic response; Initiation of transcription and translation elongation at the HIV-1 LTR; G protein signaling pathways; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Mitochondrial gene expression; Serotonin and anxiety-related events; Serotonin and anxiety; Wnt signaling; Vitamin D in inflammatory diseases; Fragile X syndrome; Alzheimer's disease; Th17 cell differentiation pathway"	"25"	"0"	"16.9"	"21.6"	"67.1"	"16.1"	"21.7"	"18.2"	"79.6"	"10.5"	"14.5"	"12.8"	"14.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15042"	"U2 snRNP-associated SURP motif-containing protein OS=Homo sapiens OX=9606 GN=U2SURP PE=1 SV=2"	"3"	"2"	"3"	"2"	"1029"	"118.2"	"8.47"	"694.27"	"4.15"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf00076, Pf01805, Pf04818, Pf08312"	"23350"	"ENSG00000163714"	"U2SURP"	"A0PJ60; hsa:23350; O15042; Q0D2M1; Q2NKQ7; Q9BR70"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"76.8"	"90.0"	"180.9"	"64.7"	"71.4"	"78.4"	"242.2"	"74.9"	"101.4"	"77.6"	"86.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99614"	"Tetratricopeptide repeat protein 1 OS=Homo sapiens OX=9606 GN=TTC1 PE=1 SV=1"	"11"	"2"	"3"	"2"	"292"	"33.5"	"4.84"	"971.46"	"4.13"	"2"	"1"	"other biological processes"	"cytosol"	"other molecular function"	"Pf00515, Pf13181"	"7265"	"ENSG00000113312"	"TTC1"	"B2RCT2; D3DQJ8; hsa:7265; Q99614; Q9BVT3"	""	""	"0"	"0"	"34.2"	"29.2"	"112.3"	"34.7"	"29.1"	"21.0"	"151.2"	"14.4"	"24.7"	"15.5"	"14.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13051"	"Uracil-DNA glycosylase OS=Homo sapiens OX=9606 GN=UNG PE=1 SV=2"	"7"	"1"	"1"	"1"	"313"	"34.6"	"9.32"	""	"4.13"	""	"1"	"DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"mitochondrion;nucleus"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf03167"	"7374"	"ENSG00000076248"	"UNG"	"A8K5M6; B2R8Y1; hsa:7374; O00637; O00719; P13051; Q93028"	""	"Base excision repair; DNA repair pathways, full network"	"2"	"0"	"11.1"	"11.1"	"24.5"	"6.4"	"9.0"	"2.0"	"55.9"	"21.2"	"26.2"	"19.3"	"26.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IWF2"	"FAD-dependent oxidoreductase domain-containing protein 2 OS=Homo sapiens OX=9606 GN=FOXRED2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"684"	"77.7"	"7.72"	"443.14"	"4.12"	"1"	"1"	"protein metabolism;other metabolic processes;stress response"	"ER/Golgi"	"other molecular function"	"Pf13738"	"80020"	"ENSG00000100350"	"FOXRED2"	"B2RDI4; hsa:80020; Q8IWF2; Q8N378; Q96BD1; Q9H5L5; Q9H6M8"	""	""	"0"	"0"	"15.7"	"18.7"	"66.2"	"14.1"	"20.3"	"14.6"	"67.8"	"8.4"	"16.1"	"13.5"	"8.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H845"	"Complex I assembly factor ACAD9, mitochondrial OS=Homo sapiens OX=9606 GN=ACAD9 PE=1 SV=1"	"4"	"1"	"1"	"1"	"621"	"68.7"	"7.96"	""	"4.12"	""	"1"	"cell organization and biogenesis;other metabolic processes"	"other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00441, Pf02770, Pf02771"	"28976"	"ENSG00000177646"	"ACAD9"	"D3DNB8; hsa:28976; Q8WXX3; Q9H845"	"Complex I biogenesis"	"Mitochondrial immune response to SARS-CoV-2; SARS-CoV-2 mitochondrial chronic oxidative stress and endothelial dysfunction"	"3"	"0"	"11.2"	"12.3"	"55.5"	"12.1"	"11.1"	"8.7"	"83.3"	"6.8"	"11.2"	"9.4"	"8.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96HC4"	"PDZ and LIM domain protein 5 OS=Homo sapiens OX=9606 GN=PDLIM5 PE=1 SV=5"	"3"	"1"	"2"	"1"	"596"	"63.9"	"8.21"	"435.18"	"4.11"	"1"	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412, Pf00595, Pf15936"	"10611"	"ENSG00000163110"	"PDLIM5"	"A8K6F9; D6RB78; E9PBF5; hsa:10611; O60705; Q56VN4; Q5UW38; Q8WVK0; Q96HC4"	"Neurexins and neuroligins"	"Extracellular vesicles in the crosstalk of cardiac cells"	"2"	"0"	"21.8"	"27.2"	"76.4"	"24.2"	"29.3"	"24.3"	"98.8"	"17.0"	"23.2"	"19.3"	"16.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P53680"	"AP-2 complex subunit sigma OS=Homo sapiens OX=9606 GN=AP2S1 PE=1 SV=2"	"8"	"1"	"2"	"1"	"142"	"17.0"	"6.18"	"374.12"	"4.10"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01217"	"1175"	"ENSG00000042753"	"AP2S1"	"B2R4Z4; hsa:1175; O75977; P53680; Q6PK67"	"Potential therapeutics for SARS; MHC class II antigen presentation; LDL clearance; Recycling pathway of L1; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; Nef Mediated CD4 Down-regulation; Retrograde neurotrophin signalling; Nef Mediated CD8 Down-regulation; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; VLDLR internalisation and degradation"	"Synaptic vesicle pathway; VEGFA-VEGFR2 signaling; GABA receptor signaling; EGF/EGFR signaling pathway; Fragile X syndrome"	"18"	"0"	"15.1"	"11.6"	"57.5"	"14.0"	"15.8"	"13.0"	"66.3"	"26.7"	"40.9"	"37.4"	"54.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P15313"	"V-type proton ATPase subunit B, kidney isoform OS=Homo sapiens OX=9606 GN=ATP6V1B1 PE=1 SV=3"	"3"	"1"	"2"	"1"	"513"	"56.8"	"5.66"	"353.25"	"4.10"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf00006, Pf02874"	"525"	"ENSG00000116039"	"ATP6V1B1"	"hsa:525; P15313; Q53FY0; Q6P4H6"	"Amino acids regulate mTORC1; ROS and RNS production in phagocytes; Insulin receptor recycling; Transferrin endocytosis and recycling; Ion channel transport"	"Proximal tubule transport"	"6"	"0"	"15.3"	"16.0"	"57.3"	"16.3"	"16.9"	"12.9"	"65.0"	"7.8"	"10.2"	"13.9"	"11.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BRJ6"	"Uncharacterized protein C7orf50 OS=Homo sapiens OX=9606 GN=C7orf50 PE=1 SV=1"	"7"	"1"	"2"	"1"	"194"	"22.1"	"9.64"	"361.50"	"4.09"	"1"	"1"	""	""	""	"Pf10180"	"84310"	"ENSG00000146540"	"C7orf50"	"hsa:84310; Q9BRJ6"	""	""	"0"	"0"	"7.5"	"12.0"	"24.5"	"7.0"	"6.7"	"6.9"	"25.3"	"2.1"	"9.1"	"4.4"	"4.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99961"	"Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1"	"4"	"1"	"2"	"1"	"368"	"41.5"	"5.43"	"410.50"	"4.09"	"1"	"1"	"cell organization and biogenesis;transport;developmental processes;signal transduction"	"other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00018, Pf03114"	"6455"	"ENSG00000141985"	"SH3GL1"	"B4DRA1; E7EVZ4; hsa:6455; M0QZV5; Q99668; Q99961"	"Cargo recognition for clathrin-mediated endocytosis; EGFR downregulation; Negative regulation of MET activity; InlB-mediated entry of Listeria monocytogenes into host cell"	"Fragile X syndrome"	"6"	"0"	"26.8"	"38.3"	"216.5"	"35.7"	"29.2"	"9.9"	"196.1"	"8.8"	"11.1"	"8.4"	"6.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15334"	"Lethal(2) giant larvae protein homolog 1 OS=Homo sapiens OX=9606 GN=LLGL1 PE=1 SV=3"	"2"	"1"	"1"	"1"	"1064"	"115.3"	"6.29"	""	"4.09"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00400, Pf08366"	"3996"	"ENSG00000131899; ENSG00000284137"	"LLGL1"	"A7MBM7; hsa:3996; O00188; Q15334; Q58F11; Q86UK6"	""	""	"0"	"0"	"6.4"	"8.2"	"28.3"	"13.1"	"12.5"	"6.7"	"50.1"	"7.8"	"14.7"	"10.2"	"11.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EV8"	"Dysbindin OS=Homo sapiens OX=9606 GN=DTNBP1 PE=1 SV=1"	"4"	"1"	"2"	"1"	"351"	"39.5"	"4.67"	"335.89"	"4.08"	"1"	"1"	"cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	""	"Pf04440"	"84062"	"ENSG00000047579"	"DTNBP1"	"A8K3V3; hsa:84062; Q5THY3; Q5THY4; Q96EV8; Q96NV2; Q9H0U2; Q9H3J5"	"Golgi Associated Vesicle Biogenesis"	"Alstrom syndrome"	"2"	"0"	"31.2"	"38.6"	"98.0"	"29.6"	"31.8"	"23.4"	"94.7"	"23.9"	"24.8"	"27.1"	"30.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14192"	"Four and a half LIM domains protein 2 OS=Homo sapiens OX=9606 GN=FHL2 PE=1 SV=3"	"8"	"2"	"2"	"2"	"279"	"32.2"	"7.55"	"349.77"	"4.07"	"1"	"1"	"RNA metabolism OR transcription;developmental processes;other biological processes"	"cytoskeleton;nucleus"	"other molecular function"	"Pf00412"	"2274"	"ENSG00000115641"	"FHL2"	"hsa:2274; Q13229; Q13644; Q14192; Q2I5I4; Q5TM15; Q9P294"	"PPARA activates gene expression"	"Androgen receptor signaling pathway; RANKL/RANK signaling pathway; Ectoderm differentiation; VEGFA-VEGFR2 signaling; 11p11.2 copy number variation syndrome"	"6"	"0"	"89.7"	"89.4"	"191.7"	"99.0"	"89.7"	"96.4"	"237.1"	"62.1"	"117.9"	"94.4"	"116.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BVC6"	"Transmembrane protein 109 OS=Homo sapiens OX=9606 GN=TMEM109 PE=1 SV=1"	"5"	"1"	"2"	"1"	"243"	"26.2"	"10.48"	"558.24"	"4.07"	"1"	"1"	"stress response;transport;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus"	"transporter activity"	"Pf14965"	"79073"	"ENSG00000110108"	"TMEM109"	"hsa:79073; Q9BVC6"	""	""	"0"	"0"	"21.9"	"20.0"	"53.4"	"16.2"	"20.2"	"16.4"	"40.0"	"8.9"	"13.8"	"9.7"	"10.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96TA2"	"ATP-dependent zinc metalloprotease YME1L1 OS=Homo sapiens OX=9606 GN=YME1L1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"773"	"86.4"	"8.76"	"535.11"	"4.07"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf00004, Pf01434, Pf17862"	"10730"	"ENSG00000136758"	"YME1L1"	"B4DNM1; D3DRV8; D3DRV9; hsa:10730; Q5T8D9; Q96TA2; Q9H1Q0; Q9UMR9"	"Processing of SMDT1"	""	"1"	"0"	"72.2"	"79.9"	"269.5"	"69.8"	"67.1"	"40.6"	"324.1"	"29.0"	"53.6"	"35.6"	"54.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"C9JLW8"	"Mapk-regulated corepressor-interacting protein 1 OS=Homo sapiens OX=9606 GN=MCRIP1 PE=1 SV=1"	"11"	"1"	"2"	"1"	"97"	"10.9"	"9.41"	"373.95"	"4.07"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	""	"Pf14799"	"348262"	"ENSG00000225663; ENSG00000288213"	"MCRIP1"	"C9JLW8; hsa:348262; Q6ZUL0"	""	""	"0"	"0"	"20.3"	"23.5"	"57.2"	"22.0"	"24.6"	"16.0"	"83.5"	"24.1"	"29.6"	"21.1"	"24.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UIA9"	"Exportin-7 OS=Homo sapiens OX=9606 GN=XPO7 PE=1 SV=3"	"2"	"1"	"2"	"1"	"1087"	"123.8"	"6.32"	"407.14"	"4.06"	"1"	"1"	"transport"	"nucleus;other cell component"	"other molecular function"	"Pf03810"	"23039"	"ENSG00000130227"	"XPO7"	"hsa:23039; O94846; Q6PJK9; Q8NEK7; Q9UIA9"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q4KMP7"	"TBC1 domain family member 10B OS=Homo sapiens OX=9606 GN=TBC1D10B PE=1 SV=3"	"3"	"1"	"1"	"1"	"808"	"87.1"	"9.19"	""	"4.06"	""	"1"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol"	"enzyme regulator activity"	"Pf00566"	"26000"	"ENSG00000169221"	"TBC1D10B"	"B9A6L0; hsa:26000; Q4KMP7; Q6IN54; Q6P530; Q71RG7; Q86VC5; Q9H8Z2; Q9NUN6; Q9UFP2"	"TBC/RABGAPs"	""	"1"	"0"	"13.2"	"10.3"	"39.0"	"12.7"	"7.3"	"8.8"	"25.3"	"4.5"	"7.8"	"8.6"	"6.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NVH1"	"DnaJ homolog subfamily C member 11 OS=Homo sapiens OX=9606 GN=DNAJC11 PE=1 SV=2"	"2"	"1"	"2"	"1"	"559"	"63.2"	"8.40"	"431.58"	"4.05"	"1"	"1"	"cell organization and biogenesis"	"other membranes;mitochondrion;nucleus"	""	"Pf00226, Pf11875"	"55735"	"ENSG00000007923"	"DNAJC11"	"hsa:55735; Q4VWF5; Q5VZN0; Q6PK20; Q6PK70; Q8NDM2; Q96CL7; Q9NVH1"	"Cristae formation"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86WJ1"	"Chromodomain-helicase-DNA-binding protein 1-like OS=Homo sapiens OX=9606 GN=CHD1L PE=1 SV=3"	"2"	"1"	"2"	"1"	"897"	"100.9"	"6.90"	"455.78"	"4.05"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00176, Pf00271"	"9557"	"ENSG00000131778"	"CHD1L"	"A5YM64; B4DDE1; B5MDZ7; hsa:9557; Q53EZ3; Q5VXX7; Q6DD94; Q6PK83; Q86WJ1; Q86XH3; Q96HF7; Q96SP3; Q9BVJ1; Q9NVV8"	"Formation of Incision Complex in GG-NER; Dual Incision in GG-NER"	"1q21.1 copy number variation syndrome; Nucleotide excision repair in xeroderma pigmentosum"	"4"	"0"	"46.8"	"39.7"	"166.4"	"49.4"	"42.6"	"33.3"	"149.2"	"23.4"	"31.7"	"26.7"	"24.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P20020"	"Plasma membrane calcium-transporting ATPase 1 OS=Homo sapiens OX=9606 GN=ATP2B1 PE=1 SV=4"	"1"	"1"	"2"	"1"	"1220"	"134.6"	"5.91"	"429.95"	"4.04"	"1"	"1"	"stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf00122, Pf00689, Pf00690, Pf00702, Pf12424, Pf13246"	"490"	"ENSG00000070961"	"ATP2B1"	"hsa:490; P20020; Q12992; Q12993; Q13819; Q13820; Q13821; Q16504; Q93082"	"Sensory processing of sound by inner hair cells of the cochlea; Ion homeostasis; Ion transport by P-type ATPases; Reduction of cytosolic Ca++ levels"	"Vitamin D receptor pathway; Splicing factor NOVA regulated synaptic proteins; Vitamin D-sensitive calcium signaling in depression; Calcium regulation in cardiac cells"	"8"	"0"	"28.8"	"29.2"	"96.4"	"20.8"	"24.6"	"17.3"	"103.8"	"18.3"	"26.7"	"21.0"	"22.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14907"	"Tax1-binding protein 3 OS=Homo sapiens OX=9606 GN=TAX1BP3 PE=1 SV=2"	"14"	"1"	"2"	"1"	"124"	"13.7"	"8.48"	"499.37"	"4.03"	"1"	"1"	"cell-cell signaling;protein metabolism;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00595, Pf02163"	"30851"	"ENSG00000213977"	"TAX1BP3"	"B2RD53; D3DTJ6; hsa:30851; O14907; Q7LCQ4"	"RHO GTPases Activate Rhotekin and Rhophilins"	""	"1"	"0"	"54.1"	"63.5"	"243.5"	"58.0"	"58.0"	"44.8"	"259.8"	"34.4"	"56.7"	"36.8"	"48.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q3SXM5"	"Inactive hydroxysteroid dehydrogenase-like protein 1 OS=Homo sapiens OX=9606 GN=HSDL1 PE=1 SV=3"	"6"	"1"	"1"	"1"	"330"	"37.0"	"8.72"	""	"4.03"	""	"1"	""	"cytoskeleton;mitochondrion;other cell component"	""	"Pf00106"	"83693"	"ENSG00000103160"	"HSDL1"	"B4DSL2; D3DUL4; hsa:83693; Q3SXM4; Q3SXM5; Q8NC98; Q9BY22"	""	""	"0"	"0"	"23.3"	"19.4"	"118.4"	"21.3"	"20.2"	"8.4"	"97.3"	"3.4"	"6.1"	"2.7"	"2.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14139"	"Ubiquitin conjugation factor E4 A OS=Homo sapiens OX=9606 GN=UBE4A PE=1 SV=2"	"1"	"1"	"2"	"1"	"1066"	"122.5"	"5.24"	"458.01"	"4.02"	"1"	"1"	"protein metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf04564, Pf10408"	"9354"	"ENSG00000110344"	"UBE4A"	"B0YJB6; hsa:9354; Q14139; Q2M1H0; Q6P5T4; Q7Z639"	"Antigen processing: Ubiquitination & Proteasome degradation"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H0W8"	"Protein SMG9 OS=Homo sapiens OX=9606 GN=SMG9 PE=1 SV=1"	"3"	"1"	"2"	"1"	"520"	"57.6"	"7.01"	"472.03"	"4.01"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes"	"cytosol"	"other molecular function"	"Pf10220"	"56006"	"ENSG00000105771"	"SMG9"	"hsa:56006; O60429; Q9H0W8; Q9H9A9"	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16718"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 OS=Homo sapiens OX=9606 GN=NDUFA5 PE=1 SV=3"	"24"	"2"	"3"	"2"	"116"	"13.5"	"5.99"	"875.26"	"3.99"	"2"	"1"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf04716"	"4698"	"ENSG00000128609"	"NDUFA5"	"B2RD98; hsa:4698; Q16718; Q5H9R2; Q6IRX7"	"Complex I biogenesis; RHOG GTPase cycle"	"Electron transport chain: OXPHOS system in mitochondria; Ciliary landscape; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"7"	"0"	"76.4"	"75.7"	"385.0"	"83.8"	"73.4"	"44.6"	"522.1"	"23.5"	"59.4"	"37.8"	"37.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99447"	"Ethanolamine-phosphate cytidylyltransferase OS=Homo sapiens OX=9606 GN=PCYT2 PE=1 SV=1"	"3"	"1"	"2"	"1"	"389"	"43.8"	"6.92"	"476.11"	"3.98"	"1"	"1"	"other metabolic processes"	"other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf01467"	"5833"	"ENSG00000185813"	"PCYT2"	"B7Z7A5; B7ZAS0; F5H8B1; hsa:5833; Q6IBM3; Q96G08; Q99447"	"Synthesis of PE"	"Trans-sulfuration, one-carbon metabolism and related pathways; Kennedy pathway from sphingolipids; Glycerolipids and glycerophospholipids"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N6H7"	"ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1"	"5"	"2"	"3"	"2"	"521"	"56.7"	"7.99"	"664.42"	"3.97"	"2"	"1"	"cell organization and biogenesis;transport"	"plasma membrane;other membranes;cytosol;ER/Golgi"	"enzyme regulator activity;other molecular function"	"Pf01412"	"84364"	"ENSG00000149182"	"ARFGAP2"	"B4DX29; B7Z9M7; D3DQQ9; hsa:84364; Q3LIF2; Q8N3I1; Q8N6H7; Q96SX7"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport; CDC42 GTPase cycle"	"IL-18 signaling pathway"	"4"	"0"	"73.0"	"97.7"	"237.5"	"81.1"	"81.0"	"57.5"	"288.0"	"62.7"	"83.8"	"86.3"	"117.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14126"	"Desmoglein-2 OS=Homo sapiens OX=9606 GN=DSG2 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1118"	"122.2"	"5.24"	"378.69"	"3.97"	"1"	"1"	"cell adhesion;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00028"	"1829"	"ENSG00000046604"	"DSG2"	"hsa:1829; Q14126; Q4KKU6"	"Formation of the cornified envelope; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; Apoptotic cleavage of cell adhesion  proteins"	"Arrhythmogenic right ventricular cardiomyopathy; GDNF signaling"	"8"	"0"	"26.4"	"31.7"	"84.0"	"24.6"	"24.5"	"22.5"	"91.9"	"15.1"	"32.6"	"14.1"	"13.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14497"	"AT-rich interactive domain-containing protein 1A OS=Homo sapiens OX=9606 GN=ARID1A PE=1 SV=3"	"1"	"2"	"3"	"2"	"2285"	"241.9"	"6.70"	"701.36"	"3.97"	"2"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01388, Pf12031"	"8289"	"ENSG00000117713"	"ARID1A"	"D3DPL1; hsa:8289; O14497; Q53FK9; Q5T0W1; Q5T0W2; Q5T0W3; Q8NFD6; Q96T89; Q9BY33; Q9HBJ5; Q9UPZ1"	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; RMTs methylate histone arginines"	"Androgen receptor network in prostate cancer; Pathways affected in adenoid cystic carcinoma; Tumor suppressor activity of SMARCB1; Thermogenesis; Kleefstra syndrome"	"7"	"0"	"80.6"	"80.6"	"269.8"	"78.1"	"83.8"	"70.4"	"282.7"	"59.6"	"90.0"	"74.1"	"78.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35030"	"Trypsin-3 OS=Homo sapiens OX=9606 GN=PRSS3 PE=1 SV=2"	"4"	"1"	"2"	"1"	"304"	"32.5"	"7.49"	"359.15"	"3.96"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;other cell component"	"other molecular function"	"Pf00089"	"5646"	"ENSG00000010438"	"PRSS3"	"A8CED1; A8CED3; A9Z1Y4; E7ES07; F8W7P3; hsa:5646; P15951; P35030; Q15665; Q5VXV0; Q6ISJ4; Q9UQV3"	"Neutrophil degranulation; Uptake of dietary cobalamins into enterocytes; Antimicrobial peptides; Alpha-defensins"	""	"4"	"0"	"88.2"	"93.6"	"148.3"	"88.9"	"90.9"	"76.9"	"122.1"	"41.6"	"75.5"	"65.3"	"66.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51812"	"Ribosomal protein S6 kinase alpha-3 OS=Homo sapiens OX=9606 GN=RPS6KA3 PE=1 SV=1"	"2"	"1"	"2"	"1"	"740"	"83.7"	"6.89"	"479.40"	"3.95"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069, Pf00433"	"6197"	"ENSG00000177189"	"RPS6KA3"	"B2R9V4; hsa:6197; P51812; Q4VAP3; Q59H26; Q5JPK8; Q7Z3Z7"	"Senescence-Associated Secretory Phenotype (SASP); Recycling pathway of L1; RSK activation; ERK/MAPK targets; CREB phosphorylation; Gastrin-CREB signalling pathway via PKC and MAPK"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; Kit receptor signaling pathway; MAPK signaling pathway; Angiopoietin-like protein 8 regulatory pathway; Thermogenesis; EGF/EGFR signaling pathway; Cytoplasmic ribosomal proteins; Insulin signaling; Host-pathogen interaction of human coronaviruses - MAPK signaling; Pleural mesothelioma; A network map of Macrophage-stimulating protein (MSP) signaling"	"18"	"0"	"9.8"	"11.1"	"54.4"	"10.0"	"6.6"	"6.7"	"84.2"	"4.6"	"5.6"	"5.0"	"4.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N9N8"	"Probable RNA-binding protein EIF1AD OS=Homo sapiens OX=9606 GN=EIF1AD PE=1 SV=1"	"10"	"1"	"2"	"1"	"165"	"19.0"	"5.21"	"455.15"	"3.94"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01176"	"84285"	"ENSG00000175376"	"EIF1AD"	"B2R4N5; hsa:84285; Q8N9N8; Q9BSC1"	""	""	"0"	"0"	"13.9"	"10.0"	"28.2"	"15.6"	"17.5"	"12.5"	"40.0"	"11.0"	"17.4"	"11.6"	"11.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75368"	"SH3 domain-binding glutamic acid-rich-like protein OS=Homo sapiens OX=9606 GN=SH3BGRL PE=1 SV=1"	"9"	"1"	"2"	"1"	"114"	"12.8"	"5.25"	"421.24"	"3.93"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf04908"	"6451"	"ENSG00000131171"	"SH3BGRL"	"hsa:6451; O75368; Q3SYL1; Q5JT50; Q6FIE8; Q9H0N8"	""	""	"0"	"0"	"79.3"	"92.4"	"409.8"	"81.8"	"86.3"	"54.4"	"547.0"	"40.8"	"82.5"	"35.4"	"28.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P45877"	"Peptidyl-prolyl cis-trans isomerase C OS=Homo sapiens OX=9606 GN=PPIC PE=1 SV=1"	"6"	"1"	"2"	"1"	"212"	"22.7"	"8.40"	"376.98"	"3.91"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other cell component"	"other molecular function"	"Pf00160"	"5480"	"ENSG00000168938"	"PPIC"	"A4LBB5; hsa:5480; P45877"	""	""	"0"	"0"	"14.7"	"26.0"	"126.3"	"30.1"	"29.6"	"17.7"	"117.8"	"16.9"	"34.8"	"19.8"	"25.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92734"	"Protein TFG OS=Homo sapiens OX=9606 GN=TFG PE=1 SV=2"	"6"	"2"	"3"	"2"	"400"	"43.4"	"5.10"	"786.54"	"3.91"	"2"	"1"	"cell organization and biogenesis;transport"	"cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00564"	"10342"	"ENSG00000114354"	"TFG"	"D3DN49; G5E9V1; hsa:10342; K0J5S8; K0J6K2; Q15656; Q92734; Q969I2"	"Signaling by ALK fusions and activated point mutants; COPII-mediated vesicle transport"	""	"2"	"0"	"60.9"	"61.5"	"237.3"	"76.7"	"57.6"	"61.8"	"250.3"	"23.0"	"40.2"	"35.2"	"23.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99598"	"Translin-associated protein X OS=Homo sapiens OX=9606 GN=TSNAX PE=1 SV=1"	"4"	"1"	"2"	"1"	"290"	"33.1"	"6.55"	"340.46"	"3.91"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf01997"	"7257"	"ENSG00000116918"	"TSNAX"	"B1APC6; hsa:7257; Q99598"	"Small interfering RNA (siRNA) biogenesis"	""	"1"	"0"	"45.0"	"70.5"	"276.4"	"63.1"	"57.8"	"42.4"	"326.5"	"44.5"	"62.9"	"47.2"	"42.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62877"	"E3 ubiquitin-protein ligase RBX1 OS=Homo sapiens OX=9606 GN=RBX1 PE=1 SV=1"	"13"	"1"	"2"	"1"	"108"	"12.3"	"6.96"	"499.96"	"3.90"	"1"	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf12678"	"9978"	"ENSG00000100387"	"RBX1"	"B2RDY1; hsa:9978; P62877; Q8N6Z8; Q9D1S2; Q9WUK9; Q9Y254"	"Potential therapeutics for SARS; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; Dual Incision in GG-NER; Regulation of expression of SLITs and ROBOs; Antigen processing: Ubiquitination & Proteasome degradation; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Degradation of DVL; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; Orc1 removal from chromatin; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Neddylation; Interleukin-1 signaling; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Regulation of BACH1 activity; NOTCH1 Intracellular Domain Regulates Transcription; Formation of TC-NER Pre-Incision Complex; Prolactin receptor signaling; DNA Damage Recognition in GG-NER; Nuclear events stimulated by ALK signaling in cancer; Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling"	"Cell cycle; Dual hijack model of Vif in HIV infection; Type 2 papillary renal cell carcinoma; NRF2-ARE regulation; Hippo-Merlin signaling dysregulation; 22q11.2 copy number variation syndrome; Nucleotide excision repair; Hijack of ubiquitination by SARS-CoV-2; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; 1p36 copy number variation syndrome"	"46"	"0"	"85.6"	"124.3"	"508.6"	"149.6"	"126.4"	"118.7"	"585.6"	"123.6"	"198.5"	"162.7"	"235.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H974"	"Queuine tRNA-ribosyltransferase accessory subunit 2 OS=Homo sapiens OX=9606 GN=QTRT2 PE=1 SV=1"	"4"	"1"	"2"	"1"	"415"	"46.7"	"6.81"	"518.61"	"3.88"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"other membranes;mitochondrion;other cell component"	"other molecular function"	"Pf01702"	"79691"	"ENSG00000151576"	"QTRT2"	"A6NGE9; B7Z472; B7Z5R2; hsa:79691; J3KR78; Q6IA59; Q9H974"	"tRNA modification in the nucleus and cytosol"	""	"1"	"0"	"13.3"	"25.9"	"158.5"	"21.7"	"22.4"	"15.1"	"209.6"	"15.8"	"17.9"	"16.9"	"28.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H490"	"Phosphatidylinositol glycan anchor biosynthesis class U protein OS=Homo sapiens OX=9606 GN=PIGU PE=1 SV=3"	"4"	"1"	"2"	"1"	"435"	"50.0"	"7.72"	"414.54"	"3.88"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi"	""	"Pf06728"	"128869"	"ENSG00000101464"	"PIGU"	"hsa:128869; Q7Z489; Q8N2F2; Q9H490"	"Attachment of GPI anchor to uPAR"	""	"1"	"0"	"14.0"	"12.7"	"43.3"	"7.7"	"11.1"	"9.8"	"32.2"	"6.7"	"10.5"	"6.7"	"7.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13243"	"Serine/arginine-rich splicing factor 5 OS=Homo sapiens OX=9606 GN=SRSF5 PE=1 SV=1"	"12"	"2"	"2"	"1"	"272"	"31.2"	"11.59"	"310.03"	"3.88"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00076"	"6430"	"ENSG00000100650"	"SRSF5"	"hsa:6430; O14797; Q13243; Q16662; Q49AD6; Q6FGE0"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"mRNA processing"	"6"	"0"	"23.5"	"29.0"	"80.8"	"17.7"	"23.0"	"12.8"	"89.7"	"12.8"	"24.2"	"15.9"	"17.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P00505"	"Aspartate aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=GOT2 PE=1 SV=3"	"4"	"1"	"2"	"1"	"430"	"47.5"	"9.01"	"478.10"	"3.87"	"1"	"1"	"other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;mitochondrion"	"other molecular function"	"Pf00155"	"2806"	"ENSG00000125166"	"GOT2"	"B4DJA6; E7ERW2; hsa:2806; P00505; Q53FL3; Q9BWA3"	"Glyoxylate metabolism and glycine degradation; Gluconeogenesis; Aspartate and asparagine metabolism; Glutamate and glutamine metabolism; Degradation of cysteine and homocysteine"	"Alanine and aspartate metabolism; Amino acid metabolism; Metabolic reprogramming in colon cancer; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Glycolysis and gluconeogenesis"	"10"	"0"	"14.1"	"17.6"	"113.5"	"20.1"	"14.1"	"11.4"	"64.0"	"7.6"	"12.9"	"9.6"	"8.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62875"	"DNA-directed RNA polymerases I, II, and III subunit RPABC5 OS=Homo sapiens OX=9606 GN=POLR2L PE=1 SV=1"	"16"	"1"	"2"	"1"	"67"	"7.6"	"7.77"	"389.76"	"3.87"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01194"	"5441"	"ENSG00000177700"	"POLR2L"	"hsa:5441; P52436; P62875; Q6FHX3"	"Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; B-WICH complex positively regulates rRNA expression; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; mRNA Splicing - Major Pathway; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"Pyrimidine metabolism; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"56"	"0"	"17.7"	"24.5"	"103.3"	"30.4"	"30.7"	"26.6"	"148.5"	"42.6"	"161.3"	"165.0"	"139.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15257"	"Serine/threonine-protein phosphatase 2A activator OS=Homo sapiens OX=9606 GN=PTPA PE=1 SV=3"	"6"	"1"	"1"	"1"	"358"	"40.6"	"5.94"	""	"3.87"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"other membranes;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf03095"	"5524"	"ENSG00000119383"	"PTPA"	"A2A347; A9IZU4; B4DXM4; hsa:5524; Q15257; Q15258; Q53GZ3; Q5TZQ2; Q9BUK1; Q9NNZ7; Q9NNZ8; Q9NNZ9"	""	"Interleukin-11 signaling pathway; Constitutive androstane receptor pathway; Nuclear receptors meta-pathway; ATM signaling in development and disease ; Wnt signaling pathway and pluripotency; Netrin-UNC5B signaling pathway; Glycogen synthesis and degradation; Cohesin complex - Cornelia de Lange syndrome"	"8"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9HCN8"	"Stromal cell-derived factor 2-like protein 1 OS=Homo sapiens OX=9606 GN=SDF2L1 PE=1 SV=2"	"9"	"1"	"2"	"1"	"221"	"23.6"	"7.03"	"415.39"	"3.85"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf02815"	"23753"	"ENSG00000128228"	"SDF2L1"	"A2RUD3; hsa:23753; Q9BRI5; Q9HCN8"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"52.1"	"144.3"	"105.4"	"56.7"	"59.5"	"62.0"	"132.7"	"72.3"	"70.7"	"55.5"	"96.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BRT2"	"Ubiquinol-cytochrome-c reductase complex assembly factor 2 OS=Homo sapiens OX=9606 GN=UQCC2 PE=1 SV=1"	"10"	"1"	"2"	"1"	"126"	"14.9"	"7.37"	"260.45"	"3.85"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"other membranes;mitochondrion;nucleus"	""	"Pf20180"	"84300"	"ENSG00000137288"	"UQCC2"	"B2R4I0; hsa:84300; Q9BRT2"	""	"Mitochondrial complex III assembly"	"1"	"0"	"45.4"	"44.9"	"175.7"	"58.5"	"55.0"	"34.1"	"213.8"	"41.3"	"68.8"	"66.7"	"87.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5JS54"	"Proteasome assembly chaperone 4 OS=Homo sapiens OX=9606 GN=PSMG4 PE=1 SV=2"	"10"	"1"	"2"	"1"	"123"	"13.8"	"6.52"	"509.98"	"3.84"	"1"	"1"	"cell organization and biogenesis"	"other cell component"	"other molecular function"	"Pf16093"	"389362"	"ENSG00000180822"	"PSMG4"	"C9J2F8; F8WBZ2; hsa:389362; Q5JS53; Q5JS54; Q5JS56"	""	""	"0"	"0"	"32.7"	"49.2"	"155.9"	"38.2"	"42.7"	"46.3"	"180.6"	"29.8"	"40.9"	"31.2"	"32.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13643"	"Four and a half LIM domains protein 3 OS=Homo sapiens OX=9606 GN=FHL3 PE=1 SV=4"	"4"	"1"	"2"	"1"	"280"	"31.2"	"6.20"	"388.27"	"3.84"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other biological processes"	"cytoskeleton;nucleus"	"cytoskeletal activity;other molecular function"	"Pf00412"	"2275"	"ENSG00000183386"	"FHL3"	"D3DPT6; hsa:2275; Q13643; Q6I9T0; Q9BVA2"	""	""	"0"	"0"	"84.1"	"81.5"	"160.0"	"87.5"	"102.2"	"121.6"	"205.1"	"69.4"	"100.1"	"92.0"	"96.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9GZT9"	"Egl nine homolog 1 OS=Homo sapiens OX=9606 GN=EGLN1 PE=1 SV=1"	"4"	"1"	"2"	"1"	"426"	"46.0"	"8.53"	"423.92"	"3.83"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01753, Pf13640"	"54583"	"ENSG00000135766"	"EGLN1"	"hsa:54583; Q8N3M8; Q9BZS8; Q9BZT0; Q9GZT9"	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"	"Photodynamic therapy-induced HIF-1 survival signaling; Type 2 papillary renal cell carcinoma; Markers of kidney cell lineage"	"4"	"0"	"18.7"	"18.1"	"52.2"	"19.2"	"18.4"	"11.6"	"85.4"	"17.7"	"25.1"	"17.7"	"22.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13136"	"Liprin-alpha-1 OS=Homo sapiens OX=9606 GN=PPFIA1 PE=1 SV=1"	"3"	"3"	"6"	"3"	"1202"	"135.7"	"6.29"	"1541.22"	"3.83"	"3"	"1"	"cell adhesion;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;other cell component"	""	"Pf00536, Pf07647"	"8500"	"ENSG00000131626"	"PPFIA1"	"A6NLE3; hsa:8500; Q13135; Q13136; Q14567; Q8N4I2"	"Glutamate Neurotransmitter Release Cycle; Serotonin Neurotransmitter Release Cycle; Norepinephrine Neurotransmitter Release Cycle; Dopamine Neurotransmitter Release Cycle; Acetylcholine Neurotransmitter Release Cycle; Receptor-type tyrosine-protein phosphatases"	""	"6"	"0"	"772.9"	"713.2"	"996.2"	"736.2"	"699.7"	"711.9"	"1084.0"	"377.8"	"600.2"	"471.0"	"413.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H773"	"dCTP pyrophosphatase 1 OS=Homo sapiens OX=9606 GN=DCTPP1 PE=1 SV=1"	"7"	"1"	"2"	"1"	"170"	"18.7"	"5.03"	"507.77"	"3.83"	"1"	"1"	"DNA metabolism;other metabolic processes;stress response"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf12643"	"79077"	"ENSG00000179958"	"DCTPP1"	"hsa:79077; Q9H773"	"Interconversion of nucleotide di- and triphosphates"	"Pyrimidine metabolism"	"2"	"0"	"38.8"	"41.5"	"337.1"	"66.4"	"60.4"	"45.3"	"326.9"	"21.1"	"35.4"	"19.2"	"20.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BXK1"	"Krueppel-like factor 16 OS=Homo sapiens OX=9606 GN=KLF16 PE=1 SV=1"	"7"	"1"	"2"	"1"	"252"	"25.4"	"9.88"	"417.32"	"3.82"	"1"	"1"	"RNA metabolism OR transcription;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00096"	"83855"	"ENSG00000129911"	"KLF16"	"hsa:83855; Q9BXK1"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BXW7"	"Haloacid dehalogenase-like hydrolase domain-containing 5 OS=Homo sapiens OX=9606 GN=HDHD5 PE=1 SV=1"	"4"	"1"	"2"	"1"	"423"	"46.3"	"8.13"	"438.69"	"3.82"	"1"	"1"	"other metabolic processes"	"mitochondrion"	""	"Pf13344"	"27440"	"ENSG00000069998"	"HDHD5"	"B2RCK5; hsa:27440; Q9BXW7; Q9BXW8; Q9NWA8; Q9NX41"	""	""	"0"	"0"	"15.3"	"11.9"	"39.4"	"15.4"	"14.9"	"12.5"	"45.4"	"7.2"	"13.4"	"9.2"	"9.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P54105"	"Methylosome subunit pICln OS=Homo sapiens OX=9606 GN=CLNS1A PE=1 SV=1"	"5"	"1"	"2"	"1"	"237"	"26.2"	"4.11"	"487.24"	"3.82"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	""	"Pf03517"	"1207"	"ENSG00000074201"	"CLNS1A"	"B2RCS9; hsa:1207; P54105; Q0VDK6; Q9NRD2; Q9NRD3"	"snRNP Assembly"	""	"1"	"0"	"93.2"	"144.7"	"466.1"	"86.7"	"78.5"	"71.5"	"574.0"	"91.0"	"83.7"	"60.3"	"76.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75153"	"Clustered mitochondria protein homolog OS=Homo sapiens OX=9606 GN=CLUH PE=1 SV=2"	"2"	"1"	"2"	"1"	"1309"	"146.6"	"6.13"	"409.08"	"3.82"	"1"	"1"	"cell organization and biogenesis"	"other cell component"	"nucleic acid binding activity"	"Pf12807, Pf13236, Pf13374, Pf13424, Pf15044"	"23277"	"ENSG00000132361"	"CLUH"	"hsa:23277; O75153; Q6AHY2; Q6P3X7; Q6ZUG8; Q8N4U7; Q9BTA3; Q9H979"	""	"Translation factors"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A6NJ78"	"12S rRNA N4-methylcytidine (m4C) methyltransferase OS=Homo sapiens OX=9606 GN=METTL15 PE=1 SV=1"	"3"	"1"	"2"	"1"	"407"	"46.1"	"8.62"	"349.50"	"3.81"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf01795"	"196074"	"ENSG00000169519"	"METTL15"	"A6NJ78; A8MRS5; B7WNU2; hsa:196074; Q3MHD3; Q8N601; Q8NBA7"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P78346"	"Ribonuclease P protein subunit p30 OS=Homo sapiens OX=9606 GN=RPP30 PE=1 SV=1"	"5"	"1"	"2"	"1"	"268"	"29.3"	"8.91"	"291.75"	"3.80"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01876"	"10556"	"ENSG00000148688"	"RPP30"	"B2R799; E9PB02; hsa:10556; P78346"	"Major pathway of rRNA processing in the nucleolus and cytosol; tRNA processing in the nucleus"	""	"2"	"0"	"26.3"	"32.7"	"108.8"	"38.1"	"30.0"	"16.1"	"93.2"	"17.4"	"25.5"	"28.1"	"24.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P48507"	"Glutamate--cysteine ligase regulatory subunit OS=Homo sapiens OX=9606 GN=GCLM PE=1 SV=1"	"5"	"1"	"2"	"1"	"274"	"30.7"	"6.02"	"413.09"	"3.78"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;stress response;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00248"	"2730"	"ENSG00000023909"	"GCLM"	"A8K334; D3DT45; hsa:2730; M5A959; P48507; Q6FHC1; Q9NPX9; Q9NU74"	"Glutathione synthesis and recycling; NFE2L2 regulating anti-oxidant/detoxification enzymes; Defective GCLC causes HAGGSD"	"Glutathione metabolism; Trans-sulfuration pathway; Trans-sulfuration, one-carbon metabolism and related pathways; Nuclear receptors meta-pathway; NRF2 pathway; Transcriptional activation by NRF2 in response to phytochemicals; Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling; Amino acid metabolism; Ferroptosis; NRF2-ARE regulation; Antiviral and anti-inflammatory effects of Nrf2 on SARS-CoV-2 pathway"	"14"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"P62891"	"60S ribosomal protein L39 OS=Homo sapiens OX=9606 GN=RPL39 PE=1 SV=2"	"20"	"1"	"2"	"1"	"51"	"6.4"	"12.56"	"395.12"	"3.78"	"1"	"1"	"protein metabolism;other metabolic processes;stress response"	"non-structural extracellular;cytosol;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00832"	"6170"	"ENSG00000198918"	"RPL39"	"hsa:6170; P02404; P39025; P62891; Q9BYF2"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"184.0"	"197.5"	"556.7"	"164.3"	"151.3"	"141.1"	"505.7"	"39.0"	"60.3"	"43.9"	"42.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NX58"	"Cell growth-regulating nucleolar protein OS=Homo sapiens OX=9606 GN=LYAR PE=1 SV=2"	"5"	"1"	"2"	"1"	"379"	"43.6"	"9.54"	"367.83"	"3.77"	"1"	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5UCC4"	"ER membrane protein complex subunit 10 OS=Homo sapiens OX=9606 GN=EMC10 PE=1 SV=1"	"5"	"1"	"2"	"1"	"262"	"27.3"	"6.13"	"465.56"	"3.76"	"1"	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"non-structural extracellular;other membranes;ER/Golgi"	""	""	"284361"	"ENSG00000161671"	"EMC10"	"hsa:284361; Q5UCC4; Q5UCC6; Q69YT5; Q6UWP3; Q86YL4; Q8N541"	""	"22q11.2 copy number variation syndrome"	"1"	"0"	"7.8"	"8.5"	"40.8"	"9.3"	"5.2"	"7.2"	"31.3"	"2.9"	"6.8"	"5.0"	"4.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQ15"	"SOSS complex subunit B1 OS=Homo sapiens OX=9606 GN=NABP2 PE=1 SV=1"	"6"	"1"	"2"	"1"	"211"	"22.3"	"9.06"	"518.94"	"3.75"	"1"	"1"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01336"	"79035"	"ENSG00000139579"	"NABP2"	"A6NDF8; hsa:79035; Q6XYC8; Q9BQ15"	"RNA polymerase II transcribes snRNA genes"	"Mesodermal commitment pathway"	"2"	"0"	"48.7"	"78.4"	"237.3"	"99.0"	"95.0"	"104.7"	"208.6"	"38.2"	"64.6"	"39.2"	"41.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NXF1"	"Testis-expressed protein 10 OS=Homo sapiens OX=9606 GN=TEX10 PE=1 SV=2"	"1"	"1"	"2"	"1"	"929"	"105.6"	"9.36"	"412.20"	"3.74"	"1"	"1"	""	"mitochondrion;nucleus"	""	"Pf12333"	"54881"	"ENSG00000136891"	"TEX10"	"B4DYV2; hsa:54881; Q5T722; Q5T723; Q8NCN8; Q8TDY0; Q9NXF1"	"Major pathway of rRNA processing in the nucleolus and cytosol"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9P0K7"	"Ankycorbin OS=Homo sapiens OX=9606 GN=RAI14 PE=1 SV=2"	"2"	"2"	"3"	"1"	"980"	"110.0"	"6.21"	"701.25"	"3.73"	"2"	"1"	"other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf00023, Pf12796"	"26064"	"ENSG00000039560"	"RAI14"	"E9PED3; hsa:26064; Q6V1W9; Q7Z5I4; Q7Z733; Q9P0K7; Q9P2L2; Q9Y3T5"	""	""	"0"	"0"	"8.6"	"8.3"	"59.8"	"17.2"	"10.9"	"8.3"	"58.4"	"5.7"	"12.5"	"10.5"	"14.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86X10"	"Ral GTPase-activating protein subunit beta OS=Homo sapiens OX=9606 GN=RALGAPB PE=1 SV=1"	"2"	"2"	"3"	"2"	"1494"	"166.7"	"6.79"	"711.82"	"3.73"	"2"	"1"	"other biological processes"	""	"enzyme regulator activity;other molecular function"	"Pf20412"	"57148"	"ENSG00000170471"	"RALGAPB"	"A2A2E8; A2A2E9; hsa:57148; Q5TG31; Q86X10; Q8N3D1; Q8WWC0; Q9H3X8; Q9UJR1; Q9ULK1; Q9Y3G9"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"	""	"1"	"0"	"41.0"	"49.0"	"123.7"	"42.8"	"49.9"	"44.6"	"123.4"	"39.0"	"118.9"	"130.7"	"146.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15139"	"Serine/threonine-protein kinase D1 OS=Homo sapiens OX=9606 GN=PRKD1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"912"	"101.6"	"6.62"	"445.82"	"3.72"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00130, Pf00169"	"5587"	"ENSG00000184304"	"PRKD1"	"A6NL64; B2RAF6; hsa:5587; Q15139"	"Sphingolipid de novo biosynthesis"	"Apoptosis modulation and signaling; Cardiac hypertrophic response; Myometrial relaxation and contraction pathways; G protein signaling pathways; VEGFA-VEGFR2 signaling; Wnt signaling pathway and pluripotency; Gastrin signaling pathway; Osteoblast differentiation and related diseases; Calcium regulation in cardiac cells"	"10"	"0"	"9.7"	"15.3"	"66.7"	"16.2"	"13.2"	"9.3"	"62.6"	"9.3"	"11.8"	"11.6"	"20.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z2Z2"	"Elongation factor-like GTPase 1 OS=Homo sapiens OX=9606 GN=EFL1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"1120"	"125.4"	"5.91"	"269.45"	"3.72"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00009, Pf00679, Pf14492"	"79631"	"ENSG00000140598"	"EFL1"	"A6NKY5; B7Z6I0; hsa:79631; Q7Z2Z2; Q9H8Z6"	""	"Genetic causes of porto-sinusoidal vascular disease"	"1"	"0"	"16.8"	"18.2"	"68.5"	"19.8"	"10.9"	"7.2"	"70.2"	"9.8"	"14.3"	"9.7"	"9.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14893"	"Gem-associated protein 2 OS=Homo sapiens OX=9606 GN=GEMIN2 PE=1 SV=1"	"8"	"1"	"1"	"1"	"280"	"31.6"	"5.58"	""	"3.71"	""	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf04938"	"8487"	"ENSG00000092208"	"GEMIN2"	"B2R9W8; hsa:8487; O14893; Q2M3B3; Q9H4F5; Q9NS77; Q9NS78; Q9NS79"	"snRNP Assembly; SARS-CoV-2 modulates host translation machinery"	""	"2"	"0"	"7.9"	"4.8"	"30.7"	"6.0"	"8.4"	"5.9"	"45.8"	"2.6"	"4.6"	"0.0"	"0.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"O00746"	"Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1"	"9"	"1"	"2"	"1"	"187"	"20.6"	"10.29"	"439.72"	"3.71"	"1"	"1"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"kinase activity;other molecular function"	"Pf00334"	"4833"	"ENSG00000103202"	"NME4"	"A2IDD0; hsa:4833; O00746; Q5U0M9"	"Interconversion of nucleotide di- and triphosphates"	"Pyrimidine metabolism"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q8WVC0"	"RNA polymerase-associated protein LEO1 OS=Homo sapiens OX=9606 GN=LEO1 PE=1 SV=1"	"2"	"1"	"2"	"1"	"666"	"75.4"	"4.51"	"361.30"	"3.71"	"1"	"1"	"cell-cell signaling;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytoskeleton;nucleus"	"other molecular function"	"Pf04004"	"123169"	"ENSG00000166477"	"LEO1"	"hsa:123169; Q8WVC0; Q96N99"	"E3 ubiquitin ligases ubiquitinate target proteins; Formation of the beta-catenin:TCF transactivating complex; Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events"	"Endoderm differentiation"	"6"	"0"	"31.6"	"28.9"	"98.9"	"29.8"	"21.2"	"26.4"	"121.3"	"27.6"	"35.6"	"31.9"	"27.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49005"	"DNA polymerase delta subunit 2 OS=Homo sapiens OX=9606 GN=POLD2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"469"	"51.3"	"5.58"	"352.74"	"3.70"	"1"	"1"	"DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf04042, Pf18018"	"5425"	"ENSG00000106628"	"POLD2"	"A4D2J4; B2R5S4; hsa:5425; P49005"	"Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Removal of the Flap Intermediate; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta); Polymerase switching on the C-strand of the telomere; Polymerase switching"	"Homologous recombination; Pyrimidine metabolism; DNA replication; Base excision repair; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"25"	"0"	"39.2"	"62.8"	"200.5"	"73.3"	"76.0"	"70.1"	"226.3"	"52.8"	"98.6"	"88.8"	"109.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UNS1"	"Protein timeless homolog OS=Homo sapiens OX=9606 GN=TIMELESS PE=1 SV=2"	"1"	"1"	"2"	"1"	"1208"	"138.6"	"5.40"	"528.14"	"3.70"	"1"	"1"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04821, Pf05029"	"8914"	"ENSG00000111602"	"TIMELESS"	"B2ZAV0; hsa:8914; O94802; Q86VM1; Q8IWH3; Q9UNS1"	"Processing of DNA double-strand break ends"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"P49247"	"Ribose-5-phosphate isomerase OS=Homo sapiens OX=9606 GN=RPIA PE=1 SV=3"	"6"	"1"	"2"	"1"	"311"	"33.2"	"8.54"	"528.32"	"3.70"	"1"	"1"	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf06026"	"22934"	"ENSG00000153574"	"RPIA"	"hsa:22934; P49247; Q541P9; Q96BJ6"	"Pentose phosphate pathway; RPIA deficiency: failed conversion of R5P to RU5P; RPIA deficiency: failed conversion of RU5P to R5P"	"Pentose phosphate metabolism; Metabolic reprogramming in colon cancer; Pentose phosphate pathway in senescent cells"	"6"	"0"	"6.2"	"8.9"	"24.0"	"7.9"	"10.0"	"5.5"	"59.8"	"6.7"	"5.7"	"4.3"	"6.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15532"	"Protein SSXT OS=Homo sapiens OX=9606 GN=SS18 PE=1 SV=3"	"3"	"1"	"2"	"1"	"418"	"45.9"	"6.46"	"516.48"	"3.70"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf05030"	"6760"	"ENSG00000141380"	"SS18"	"B0YJ95; hsa:6760; Q15532; Q16404; Q4VAX1; Q9BXC6"	""	""	"0"	"0"	"29.9"	"23.1"	"75.0"	"29.2"	"23.2"	"28.1"	"161.6"	"31.9"	"53.5"	"39.1"	"31.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3D3"	"28S ribosomal protein S16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS16 PE=1 SV=1"	"9"	"1"	"2"	"1"	"137"	"15.3"	"9.50"	"414.67"	"3.70"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;cytosol;mitochondrion;translational apparatus"	"other molecular function"	"Pf00886"	"51021"	"ENSG00000182180"	"MRPS16"	"B4E032; hsa:51021; Q96Q60; Q9Y3D3"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"64.6"	"76.3"	"245.6"	"83.9"	"69.4"	"62.7"	"293.2"	"43.6"	"60.4"	"53.0"	"56.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7L7X3"	"Serine/threonine-protein kinase TAO1 OS=Homo sapiens OX=9606 GN=TAOK1 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1001"	"116.0"	"7.65"	"526.42"	"3.69"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;cytoskeletal activity;kinase activity;other molecular function"	"Pf00069"	"57551"	"ENSG00000160551"	"TAOK1"	"A2RUT8; B7ZLV6; hsa:57551; Q7L7X3; Q96L75; Q9H2K7; Q9H7S5; Q9P2I6"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"Microtubule cytoskeleton regulation; MAPK signaling pathway"	"8"	"0"	"23.1"	"22.7"	"48.6"	"17.7"	"25.3"	"15.5"	"46.5"	"13.8"	"21.0"	"25.3"	"25.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IYB5"	"Stromal membrane-associated protein 1 OS=Homo sapiens OX=9606 GN=SMAP1 PE=1 SV=2"	"4"	"2"	"3"	"2"	"467"	"50.4"	"8.75"	"618.42"	"3.68"	"2"	"1"	"other biological processes"	"plasma membrane;other membranes;other cell component"	"enzyme regulator activity;other molecular function"	"Pf01412"	"60682"	"ENSG00000112305"	"SMAP1"	"hsa:60682; Q53H70; Q5SYQ2; Q6PK24; Q8IYB5; Q8NDH4; Q96L38; Q96L39; Q9H8X4"	""	""	"0"	"0"	"75.3"	"74.5"	"224.4"	"68.5"	"71.0"	"54.3"	"320.8"	"71.3"	"100.8"	"89.5"	"72.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92974"	"Rho guanine nucleotide exchange factor 2 OS=Homo sapiens OX=9606 GN=ARHGEF2 PE=1 SV=4"	"1"	"1"	"2"	"1"	"986"	"111.5"	"7.27"	"555.17"	"3.68"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00621, Pf17838"	"9181"	"ENSG00000116584"	"ARHGEF2"	"D3DVA6; hsa:9181; O75142; Q15079; Q5VY92; Q8TDA3; Q8WUG4; Q92974; Q9H023"	"RHOA GTPase cycle; NRAGE signals death through JNK; G alpha (12/13) signalling events; RHOB GTPase cycle"	"Pathogenic Escherichia coli infection"	"5"	"0"	"50.0"	"43.0"	"128.4"	"52.7"	"48.9"	"41.7"	"153.6"	"32.8"	"47.2"	"43.9"	"46.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96NY7"	"Chloride intracellular channel protein 6 OS=Homo sapiens OX=9606 GN=CLIC6 PE=2 SV=3"	"7"	"1"	"1"	"1"	"704"	"73.0"	"4.37"	""	"3.68"	""	"1"	"transport;other biological processes"	"plasma membrane;other membranes;other cell component"	"signal transduction activity or receptor binding;transporter activity"	"Pf13410"	"54102"	"ENSG00000159212"	"CLIC6"	"A8K0U8; hsa:54102; Q8IX31; Q96NY7"	""	""	"0"	"0"	"7.8"	"16.4"	"52.9"	"23.8"	"20.4"	"18.5"	"59.9"	"10.0"	"16.1"	"12.6"	"17.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P015"	"39S ribosomal protein L15, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL15 PE=1 SV=1"	"4"	"1"	"2"	"1"	"296"	"33.4"	"10.01"	"354.68"	"3.68"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00828"	"29088"	"ENSG00000137547"	"MRPL15"	"hsa:29088; Q96Q54; Q9H0Y1; Q9P015"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"21.9"	"19.6"	"55.3"	"19.5"	"27.4"	"15.9"	"62.7"	"12.0"	"15.5"	"19.0"	"19.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5VTR2"	"E3 ubiquitin-protein ligase BRE1A OS=Homo sapiens OX=9606 GN=RNF20 PE=1 SV=2"	"1"	"1"	"2"	"1"	"975"	"113.6"	"5.94"	"446.76"	"3.68"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00097"	"56254"	"ENSG00000155827"	"RNF20"	"A7MCT5; hsa:56254; Q2TB34; Q5VTR2; Q69YL5; Q6P527; Q8N3J4; Q96JD3; Q9H9Y7; Q9HA51; Q9NUR4; Q9NWQ3; Q9NX83"	"E3 ubiquitin ligases ubiquitinate target proteins; RHOBTB1 GTPase cycle"	"ATM signaling in development and disease"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9BV38"	"WD repeat-containing protein 18 OS=Homo sapiens OX=9606 GN=WDR18 PE=1 SV=2"	"3"	"1"	"2"	"1"	"432"	"47.4"	"6.70"	"358.09"	"3.67"	"1"	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf00400, Pf14077"	"57418"	"ENSG00000065268"	"WDR18"	"hsa:57418; O60390; Q9BV38; Q9BWR2"	"Major pathway of rRNA processing in the nucleolus and cytosol"	""	"1"	"0"	"38.0"	"42.5"	"151.1"	"49.0"	"49.9"	"38.8"	"137.4"	"15.3"	"27.7"	"21.2"	"20.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H2H8"	"Peptidyl-prolyl cis-trans isomerase-like 3 OS=Homo sapiens OX=9606 GN=PPIL3 PE=1 SV=1"	"8"	"1"	"2"	"1"	"161"	"18.1"	"6.79"	"383.06"	"3.65"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00160"	"53938"	"ENSG00000240344"	"PPIL3"	"hsa:53938; Q86WF9; Q96IA9; Q9BXZ1; Q9H2H8"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z4G4"	"tRNA (guanine(10)-N2)-methyltransferase homolog OS=Homo sapiens OX=9606 GN=TRMT11 PE=1 SV=1"	"3"	"1"	"2"	"1"	"463"	"53.4"	"7.78"	"442.59"	"3.64"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01170"	"60487"	"ENSG00000066651"	"TRMT11"	"E1P570; hsa:60487; Q5JY11; Q6PGQ5; Q7Z4G4; Q9HC13"	"tRNA modification in the nucleus and cytosol"	""	"1"	"0"	"34.5"	"40.5"	"131.7"	"37.9"	"41.8"	"29.0"	"124.9"	"18.5"	"35.4"	"28.9"	"35.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96CB8"	"Integrator complex subunit 12 OS=Homo sapiens OX=9606 GN=INTS12 PE=1 SV=1"	"3"	"1"	"2"	"1"	"462"	"48.8"	"9.69"	"281.00"	"3.63"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00628"	"57117"	"ENSG00000138785"	"INTS12"	"B2RC48; hsa:57117; Q3B6Z3; Q96CB8; Q9HD71"	"RNA polymerase II transcribes snRNA genes"	""	"1"	"0"	"39.5"	"33.0"	"78.4"	"46.6"	"48.7"	"33.4"	"114.6"	"39.4"	"56.1"	"47.9"	"51.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y547"	"Intraflagellar transport protein 25 homolog OS=Homo sapiens OX=9606 GN=HSPB11 PE=1 SV=1"	"8"	"1"	"2"	"1"	"144"	"16.3"	"5.03"	"269.12"	"3.62"	"1"	"1"	"cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"cytoskeleton;other cell component"	"other molecular function"	"Pf00754"	"51668"	"ENSG00000081870"	"IFT25"	"A6NG57; D3DQ45; hsa:51668; Q9Y547; Q9Y684"	"Intraflagellar transport"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein; Genes related to primary cilium development (based on CRISPR); GDNF/RET signaling axis; Alstrom syndrome"	"6"	"0"	"34.4"	"40.9"	"133.8"	"18.5"	"38.5"	"25.2"	"191.0"	"26.4"	"22.3"	"26.2"	"25.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6GYQ0"	"Ral GTPase-activating protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=RALGAPA1 PE=1 SV=1"	"1"	"1"	"2"	"1"	"2036"	"229.7"	"6.19"	"359.78"	"3.61"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02145, Pf20412"	"253959"	"ENSG00000174373"	"RALGAPA1"	"A6NMA4; B9EK38; C5NU19; hsa:253959; O94960; Q6GYP9; Q6GYQ0; Q6ZT23; Q86YF3; Q86YF5; Q8ND69"	"RHOH GTPase cycle"	""	"1"	"0"	"5.7"	"3.5"	"16.4"	"6.3"	"6.8"	"6.0"	"15.2"	"3.0"	"15.9"	"20.2"	"22.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BVK6"	"Transmembrane emp24 domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TMED9 PE=1 SV=2"	"5"	"1"	"2"	"1"	"235"	"27.3"	"8.02"	"346.70"	"3.61"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf01105"	"54732"	"ENSG00000184840"	"TMED9"	"hsa:54732; Q14437; Q8WZ61; Q9BVK6"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport"	""	"2"	"0"	"161.0"	"161.7"	"806.9"	"156.7"	"137.2"	"77.3"	"771.0"	"39.7"	"77.5"	"56.2"	"67.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2Z0"	"Protein SGT1 homolog OS=Homo sapiens OX=9606 GN=SUGT1 PE=1 SV=3"	"6"	"1"	"1"	"1"	"365"	"41.0"	"5.16"	""	"3.61"	""	"1"	"cell cycle OR cell proliferation;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf04969, Pf05002"	"10910"	"ENSG00000165416"	"SUGT1"	"A2A303; hsa:10910; Q5JAK5; Q5TAM6; Q6VXY6; Q9Y2Z0"	"The NLRP3 inflammasome; Purinergic signaling in leishmaniasis infection"	"Nucleotide-binding oligomerization domain (NOD) pathway"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q96T60"	"Bifunctional polynucleotide phosphatase/kinase OS=Homo sapiens OX=9606 GN=PNKP PE=1 SV=1"	"3"	"1"	"2"	"1"	"521"	"57.0"	"8.46"	"444.72"	"3.61"	"1"	"1"	"DNA metabolism;other metabolic processes;stress response;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf08645, Pf13671, Pf17913"	"11284"	"ENSG00000039650"	"PNKP"	"hsa:11284; Q96T60; Q9BUL2; Q9P1V2; Q9UKU8; Q9UNF8; Q9UNI0"	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"	"Base excision repair; DNA repair pathways, full network"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q99417"	"c-Myc-binding protein OS=Homo sapiens OX=9606 GN=MYCBP PE=1 SV=3"	"19"	"1"	"2"	"1"	"103"	"12.0"	"5.91"	"417.69"	"3.61"	"1"	"1"	"RNA metabolism OR transcription;other biological processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	""	"26292"	"ENSG00000214114"	"MYCBP"	"B2R4N0; hsa:26292; Q5TA64; Q96HE2; Q99417"	""	"Pathways affected in adenoid cystic carcinoma"	"1"	"0"	"23.6"	"23.2"	"162.0"	"27.8"	"24.8"	"18.1"	"210.1"	"10.2"	"17.3"	"17.5"	"17.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95816"	"BAG family molecular chaperone regulator 2 OS=Homo sapiens OX=9606 GN=BAG2 PE=1 SV=1"	"8"	"1"	"2"	"1"	"211"	"23.8"	"6.70"	"511.46"	"3.60"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	""	"9532"	"ENSG00000112208"	"BAG2"	"B4DXE2; hsa:9532; O95816; Q08AS9; Q6FID0"	"Regulation of HSF1-mediated heat shock response"	"Pleural mesothelioma"	"2"	"0"	"82.5"	"73.4"	"260.2"	"68.3"	"88.9"	"49.8"	"316.5"	"42.8"	"60.2"	"50.4"	"47.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HAV4"	"Exportin-5 OS=Homo sapiens OX=9606 GN=XPO5 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1204"	"136.2"	"5.80"	"355.15"	"3.60"	"1"	"1"	"RNA metabolism OR transcription;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf08389, Pf19273"	"57510"	"ENSG00000124571"	"XPO5"	"hsa:57510; Q5JTE6; Q96G48; Q96HN3; Q9BWM6; Q9BZV5; Q9H9M4; Q9HAV4; Q9NT89; Q9NW39; Q9ULC9"	"MicroRNA (miRNA) biogenesis"	"miRNA biogenesis; exRNA mechanism of action and biogenesis; Primary ovarian insufficiency"	"4"	"0"	"56.1"	"50.7"	"222.2"	"54.7"	"51.5"	"35.8"	"190.7"	"16.4"	"33.8"	"24.6"	"21.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14949"	"Cytochrome b-c1 complex subunit 8 OS=Homo sapiens OX=9606 GN=UQCRQ PE=1 SV=4"	"13"	"1"	"1"	"1"	"82"	"9.9"	"10.08"	""	"3.60"	""	"1"	"other metabolic processes;developmental processes"	"other membranes;mitochondrion"	""	"Pf02939"	"27089"	"ENSG00000164405"	"UQCRQ"	"hsa:27089; O14949; Q5FVE2; Q9BV88; Q9T2V7"	"Respiratory electron transport"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex III assembly"	"4"	"0"	"39.8"	"31.0"	"99.4"	"46.1"	"48.8"	"44.4"	"142.8"	"16.5"	"32.4"	"36.1"	"18.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75150"	"E3 ubiquitin-protein ligase BRE1B OS=Homo sapiens OX=9606 GN=RNF40 PE=1 SV=5"	"1"	"1"	"2"	"1"	"1001"	"113.6"	"6.29"	"458.02"	"3.59"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00097"	"9810"	"ENSG00000103549"	"RNF40"	"A0A024QZG0; hsa:9810; O75150; Q6AHZ6; Q6N005; Q7L3T6; Q8N615; Q96T18; Q9BSV9; Q9HC82"	"E3 ubiquitin ligases ubiquitinate target proteins"	"ATM signaling in development and disease"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14671"	"Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3"	"1"	"1"	"2"	"1"	"1186"	"126.4"	"6.84"	"567.93"	"3.59"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00806"	"9698"	"ENSG00000134644"	"PUM1"	"A8K6W4; B4DG92; D3DPN3; E9PCJ0; hsa:9698; Q14671; Q53HH5; Q5VXY7; Q9HAN1"	"Golgi Associated Vesicle Biogenesis"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"A4D1E9"	"GTP-binding protein 10 OS=Homo sapiens OX=9606 GN=GTPBP10 PE=1 SV=1"	"4"	"1"	"2"	"1"	"387"	"42.9"	"9.03"	"417.90"	"3.59"	"1"	"1"	"other biological processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01018, Pf01926"	"85865"	"ENSG00000105793"	"GTPBP10"	"A4D1E9; B4DFY6; hsa:85865; Q3B7A6; Q5H9V2; Q8IXG8; Q8N982; Q8WU16; Q9BSP1; Q9Y6T6"	""	""	"0"	"0"	"18.8"	"16.7"	"72.1"	"17.5"	"18.3"	"13.5"	"54.1"	"8.2"	"8.2"	"7.7"	"12.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5X1"	"Sorting nexin-9 OS=Homo sapiens OX=9606 GN=SNX9 PE=1 SV=1"	"3"	"1"	"2"	"1"	"595"	"66.6"	"5.58"	"471.25"	"3.58"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf00018, Pf00787, Pf10456"	"51429"	"ENSG00000130340"	"SNX9"	"hsa:51429; Q9BSI7; Q9BVM1; Q9UJH6; Q9UP20; Q9Y5X1"	"Clathrin-mediated endocytosis; Golgi Associated Vesicle Biogenesis"	""	"2"	"0"	"15.8"	"18.3"	"55.1"	"20.0"	"17.9"	"22.8"	"61.6"	"33.4"	"95.5"	"109.7"	"162.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BV81"	"ER membrane protein complex subunit 6 OS=Homo sapiens OX=9606 GN=EMC6 PE=1 SV=1"	"12"	"1"	"2"	"1"	"110"	"12.0"	"10.07"	"436.44"	"3.58"	"1"	"1"	"cell organization and biogenesis;other metabolic processes"	"other membranes;ER/Golgi"	""	"Pf07019"	"83460"	"ENSG00000127774"	"EMC6"	"hsa:83460; Q9BV81"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96DG6"	"Carboxymethylenebutenolidase homolog OS=Homo sapiens OX=9606 GN=CMBL PE=1 SV=1"	"4"	"1"	"2"	"1"	"245"	"28.0"	"7.18"	"428.61"	"3.58"	"1"	"1"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf01738"	"134147"	"ENSG00000164237"	"CMBL"	"D3DTC7; hsa:134147; Q8TED6; Q96DG6"	"Phase I - Functionalization of compounds"	""	"1"	"0"	"44.7"	"56.9"	"224.0"	"67.3"	"47.4"	"52.9"	"196.6"	"21.8"	"35.6"	"27.6"	"26.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14950"	"Myosin regulatory light chain 12B OS=Homo sapiens OX=9606 GN=MYL12B PE=1 SV=2"	"12"	"1"	"2"	"1"	"172"	"19.8"	"4.84"	"430.63"	"3.57"	"1"	"1"	"other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf08976, Pf13405"	"103910; 10627"	"ENSG00000118680"	"MYL12B"	"D3DUH6; hsa:103910; O14950; Q13182; Q7Z5Z4"	"RHO GTPases activate CIT; EPHA-mediated growth cone collapse; Sema4D induced cell migration and growth-cone collapse; Smooth Muscle Contraction; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; RHO GTPases activate PAKs"	"Thyroid stimulating hormone (TSH) signaling pathway; Focal adhesion"	"9"	"0"	"17.4"	"19.8"	"74.1"	"22.8"	"14.9"	"11.8"	"55.7"	"9.7"	"13.0"	"8.3"	"12.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H501"	"ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1"	"1"	"1"	"2"	"1"	"851"	"98.7"	"5.11"	"443.97"	"3.55"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf08159"	"51575"	"ENSG00000089048"	"ESF1"	"hsa:51575; Q86X92; Q9H501; Q9H9Q5; Q9HA35; Q9NX93; Q9P1S6"	""	""	"0"	"0"	"15.8"	"20.1"	"68.4"	"18.7"	"13.9"	"13.5"	"62.2"	"9.7"	"17.8"	"11.3"	"14.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5A9"	"YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2"	"3"	"2"	"3"	"2"	"579"	"62.3"	"8.79"	"664.87"	"3.55"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity"	"Pf04146"	"51441"	"ENSG00000198492"	"YTHDF2"	"A6NKG4; A8K966; B4E1G7; D3DPM8; hsa:51441; Q5VSZ9; Q8TDH0; Q9BUJ5; Q9Y5A9"	""	""	"0"	"0"	"206.3"	"228.0"	"604.0"	"197.9"	"184.2"	"140.3"	"784.9"	"135.8"	"190.1"	"148.5"	"195.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z4W1"	"L-xylulose reductase OS=Homo sapiens OX=9606 GN=DCXR PE=1 SV=2"	"5"	"1"	"2"	"1"	"244"	"25.9"	"8.10"	"318.84"	"3.54"	"1"	"1"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf13561"	"51181"	"ENSG00000169738"	"DCXR"	"hsa:51181; Q7Z4W1; Q9BTZ3; Q9UHY9"	"Formation of xylulose-5-phosphate; Essential pentosuria"	""	"2"	"0"	"13.1"	"18.3"	"40.4"	"18.3"	"18.2"	"16.2"	"53.0"	"19.3"	"19.0"	"10.7"	"21.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99102"	"Mucin-4 OS=Homo sapiens OX=9606 GN=MUC4 PE=1 SV=4"	"2"	"1"	"1"	"1"	"2169"	"231.4"	"6.27"	""	"3.54"	""	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"20.3"	"19.4"	"34.6"	"16.9"	"14.8"	"20.5"	"58.1"	"11.8"	"18.6"	"14.8"	"20.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15831"	"Serine/threonine-protein kinase STK11 OS=Homo sapiens OX=9606 GN=STK11 PE=1 SV=1"	"4"	"1"	"2"	"1"	"433"	"48.6"	"7.43"	"461.37"	"3.53"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069"	"6794"	"ENSG00000118046"	"STK11"	"B2RBX7; E7EW76; hsa:6794; Q15831"	"Regulation of TP53 Activity through Phosphorylation; Energy dependent regulation of mTOR by LKB1-AMPK; FOXO-mediated transcription of cell death genes; AMPK inhibits chREBP transcriptional activation activity"	"AMP-activated protein kinase signaling; mir-124 predicted interactions with cell cycle and differentiation ; ATM signaling in development and disease ; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Head and neck squamous cell carcinoma; Female steroid hormones in cardiomyocyte energy metabolism"	"12"	"0"	"8.4"	"11.4"	"31.0"	"7.4"	"5.2"	"5.8"	"39.6"	"15.1"	"71.1"	"81.5"	"79.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UK76"	"Jupiter microtubule associated homolog 1 OS=Homo sapiens OX=9606 GN=JPT1 PE=1 SV=3"	"10"	"1"	"2"	"1"	"154"	"16.0"	"5.60"	"507.33"	"3.53"	"1"	"1"	""	"other membranes;nucleus;other cell component"	""	"Pf17054"	"51155"	"ENSG00000189159"	"JPT1"	"B2R6K3; hsa:51155; Q53FG7; Q7Z2D2; Q7Z2F0; Q9UK76"	""	""	"0"	"0"	"44.3"	"35.9"	"152.5"	"35.2"	"30.6"	"18.2"	"207.1"	"23.1"	"16.8"	"24.5"	"13.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P1N9"	"Putative deoxyribonuclease TATDN1 OS=Homo sapiens OX=9606 GN=TATDN1 PE=1 SV=2"	"4"	"1"	"1"	"1"	"297"	"33.6"	"6.96"	""	"3.52"	""	"1"	"DNA metabolism"	"nucleus"	"other molecular function"	"Pf01026"	"83940"	"ENSG00000147687"	"TATDN1"	"B2R5J0; hsa:83940; Q6P1N9; Q8TD02; Q9BY40"	""	""	"0"	"0"	"59.0"	"63.6"	"210.3"	"57.2"	"52.0"	"47.0"	"206.3"	"28.4"	"63.0"	"116.1"	"301.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6SPF0"	"Atherin OS=Homo sapiens OX=9606 GN=SAMD1 PE=1 SV=1"	"4"	"1"	"1"	"1"	"538"	"56.0"	"7.58"	""	"3.51"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"other molecular function"	"Pf00536"	"90378"	"ENSG00000288488"	"SAMD1"	"hsa:90378; Q6P0R3; Q6PIS7; Q6SPF0; Q96IM4"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"O00193"	"Small acidic protein OS=Homo sapiens OX=9606 GN=SMAP PE=1 SV=1"	"17"	"3"	"4"	"3"	"183"	"20.3"	"4.72"	"1115.38"	"3.51"	"3"	"1"	""	""	""	"Pf15477"	"10944"	"ENSG00000110696"	"SMAP"	"B2RD28; hsa:10944; O00193"	""	""	"0"	"0"	"380.4"	"486.4"	"1904.7"	"497.9"	"577.6"	"891.4"	"3437.6"	"452.4"	"569.8"	"523.2"	"486.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19525"	"Interferon-induced, double-stranded RNA-activated protein kinase OS=Homo sapiens OX=9606 GN=EIF2AK2 PE=1 SV=2"	"2"	"1"	"2"	"1"	"551"	"62.1"	"8.40"	"346.69"	"3.51"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;kinase activity;other molecular function"	"Pf00035, Pf00069"	"5610"	"ENSG00000055332"	"EIF2AK2"	"A8K3P0; D6W584; E9PC80; hsa:5610; P19525; Q52M43; Q7Z6F6; Q9UIR4"	"ISG15 antiviral mechanism; Interferon alpha/beta signaling; Inhibition of PKR"	"Translation factors; Alzheimer's disease and miRNA effects; Ebola virus infection in host; Measles virus infection; Type I interferon induction and signaling during SARS-CoV-2 infection; Host-pathogen interaction of human coronaviruses - interferon induction; Alzheimer's disease; Roles of ceramides in development of insulin resistance; Type II interferon signaling"	"12"	"0"	"29.7"	"30.1"	"110.1"	"25.3"	"18.4"	"17.2"	"68.9"	"10.6"	"9.2"	"10.8"	"10.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60749"	"Sorting nexin-2 OS=Homo sapiens OX=9606 GN=SNX2 PE=1 SV=2"	"4"	"2"	"3"	"2"	"519"	"58.4"	"5.12"	"841.43"	"3.50"	"2"	"1"	"cell organization and biogenesis;transport"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00787, Pf03700, Pf09325"	"6643"	"ENSG00000205302"	"SNX2"	"B3KN44; B4DEK4; B7Z408; hsa:6643; O43650; O60749; P82862; Q53XK8; Q597H6; Q9BTS8"	"Golgi Associated Vesicle Biogenesis"	""	"1"	"0"	"73.5"	"74.8"	"334.9"	"84.0"	"69.8"	"51.5"	"397.3"	"39.4"	"55.1"	"55.9"	"50.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UNY4"	"Transcription termination factor 2 OS=Homo sapiens OX=9606 GN=TTF2 PE=1 SV=2"	"2"	"2"	"3"	"1"	"1162"	"129.5"	"8.37"	"665.14"	"3.50"	"2"	"1"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf06839"	"8458"	"ENSG00000116830"	"TTF2"	"A8K4Q2; hsa:8458; O75921; Q5T2K7; Q5VVU8; Q8N6I8; Q9UNY4"	""	"Thyroid stimulating hormone (TSH) signaling pathway; Thyroid hormones production and peripheral downstream signaling effects"	"2"	"0"	"18.2"	"18.2"	"55.3"	"14.3"	"16.4"	"11.6"	"37.7"	"7.5"	"9.6"	"11.3"	"9.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q709F0"	"Acyl-CoA dehydrogenase family member 11 OS=Homo sapiens OX=9606 GN=ACAD11 PE=1 SV=3"	"3"	"2"	"3"	"2"	"780"	"87.2"	"8.02"	"654.24"	"3.49"	"2"	"1"	"other metabolic processes"	"other membranes;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00441, Pf01636, Pf02770, Pf02771"	"84129"	"ENSG00000240303"	"ACAD11"	"hsa:84129; Q08AF0; Q658N9; Q658Y2; Q6ZND2; Q709F0; Q8WUT6; Q9H9R3"	"Mitochondrial Fatty Acid Beta-Oxidation"	"p53 transcriptional gene network"	"2"	"0"	"129.2"	"94.5"	"296.8"	"86.4"	"95.4"	"71.5"	"312.5"	"75.4"	"131.4"	"188.2"	"243.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NFH3"	"Nucleoporin Nup43 OS=Homo sapiens OX=9606 GN=NUP43 PE=1 SV=1"	"3"	"1"	"2"	"1"	"380"	"42.1"	"5.63"	"430.10"	"3.49"	"1"	"1"	"cell cycle OR cell proliferation;transport;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf00400"	"348995"	"ENSG00000120253"	"NUP43"	"B4E2F0; hsa:348995; Q8NFH3; Q9H8S0"	"Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Regulation of HSF1-mediated heat shock response; ISG15 antiviral mechanism; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Vpr-mediated nuclear import of PICs; SUMOylation of chromatin organization proteins; SUMOylation of DNA damage response and repair proteins; SUMOylation of SUMOylation proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transport of Mature mRNA derived from an Intron-Containing Transcript; tRNA processing in the nucleus; HCMV Late Events; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; HCMV Early Events; EML4 and NUDC in mitotic spindle formation; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; snRNP Assembly; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); SARS-CoV-2 activates/modulates innate and adaptive immune responses; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Postmitotic nuclear pore complex (NPC) reformation"	""	"35"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31151"	"Protein S100-A7 OS=Homo sapiens OX=9606 GN=S100A7 PE=1 SV=4"	"11"	"1"	"2"	"1"	"101"	"11.5"	"6.77"	"418.48"	"3.48"	"1"	"1"	"stress response;developmental processes;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01023"	"6278"	"ENSG00000143556"	"S100A7"	"hsa:6278; P31151; Q5SY67; Q6FGE3; Q9H1E2"	"Neutrophil degranulation; Metal sequestration by antimicrobial proteins"	""	"2"	"0"	"57.9"	"71.5"	"41.6"	"22.1"	"16.9"	"18.5"	"63.8"	"22.4"	"29.1"	"21.8"	"20.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08240"	"Signal recognition particle receptor subunit alpha OS=Homo sapiens OX=9606 GN=SRPRA PE=1 SV=2"	"4"	"1"	"1"	"1"	"638"	"69.8"	"8.95"	""	"3.48"	""	"1"	"cell organization and biogenesis;transport"	"other membranes;ER/Golgi"	"other molecular function"	"Pf00448, Pf02881, Pf04086"	"6734"	"ENSG00000182934"	"SRPRA"	"A6NIB3; B2R5Z8; B4E0H3; E9PJS4; hsa:6734; P08240; Q9BVJ4"	"SRP-dependent cotranslational protein targeting to membrane; XBP1(S) activates chaperone genes"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q96DE0"	"U8 snoRNA-decapping enzyme OS=Homo sapiens OX=9606 GN=NUDT16 PE=1 SV=2"	"8"	"1"	"2"	"1"	"195"	"21.3"	"6.89"	"453.15"	"3.46"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00293"	"131870"	"ENSG00000198585"	"NUDT16"	"B4E3B4; E9PED4; F5GYJ1; hsa:131870; Q96DE0; Q96N82"	"Phosphate bond hydrolysis by NUDT proteins"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"P04179"	"Superoxide dismutase [Mn], mitochondrial OS=Homo sapiens OX=9606 GN=SOD2 PE=1 SV=3"	"6"	"1"	"2"	"1"	"222"	"24.7"	"8.25"	"348.59"	"3.46"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00081, Pf02777"	"6648"	"ENSG00000291237"	"SOD2"	"B2R7R1; B3KUK2; B4DL20; B4E3K9; E1P5A9; hsa:6648; P04179; P78434; Q16792; Q5TCM1; Q96EE6; Q9P2Z3"	"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Detoxification of Reactive Oxygen Species; Transcriptional activation of mitochondrial biogenesis; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"	"Selenium micronutrient network; Vitamin B12 metabolism; Folate metabolism; VEGFA-VEGFR2 signaling; Oxidative stress response"	"10"	"0"	"34.7"	"33.9"	"117.5"	"35.1"	"34.1"	"27.0"	"157.4"	"26.6"	"24.8"	"28.8"	"24.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UPY6"	"Wiskott-Aldrich syndrome protein family member 3 OS=Homo sapiens OX=9606 GN=WASF3 PE=1 SV=2"	"3"	"1"	"2"	"1"	"502"	"55.3"	"6.43"	"389.23"	"3.45"	"1"	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02205"	"10810"	"ENSG00000132970"	"WASF3"	"hsa:10810; O94974; Q86VQ2; Q9UPY6"	"Regulation of actin dynamics for phagocytic cup formation; VEGFA-VEGFR2 Pathway; RAC1 GTPase cycle; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs"	""	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07384"	"Calpain-1 catalytic subunit OS=Homo sapiens OX=9606 GN=CAPN1 PE=1 SV=1"	"7"	"3"	"4"	"3"	"714"	"81.8"	"5.67"	"1112.65"	"3.44"	"3"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00648, Pf01067, Pf13833"	"823"	"ENSG00000014216"	"CAPN1"	"hsa:823; P07384; Q2TTR0; Q6DHV4"	"Formation of the cornified envelope; Degradation of the extracellular matrix; Neutrophil degranulation; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"	"Integrin-mediated cell adhesion; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"7"	"0"	"35.7"	"30.4"	"133.4"	"28.9"	"33.7"	"22.1"	"153.3"	"15.7"	"22.3"	"15.7"	"18.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6YP21"	"Kynurenine--oxoglutarate transaminase 3 OS=Homo sapiens OX=9606 GN=KYAT3 PE=1 SV=1"	"3"	"1"	"2"	"1"	"454"	"51.4"	"8.19"	"459.75"	"3.44"	"1"	"1"	"other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf00155"	"56267"	"ENSG00000137944"	"KYAT3"	"B3KQ13; hsa:56267; O95335; Q5JS27; Q5T9T7; Q5T9T8; Q6AI27; Q6ICW1; Q6YP21; Q9BVY5"	"Tryptophan catabolism"	"Tryptophan metabolism"	"2"	"0"	"10.9"	"11.3"	"67.2"	"11.5"	"11.8"	"5.6"	"122.8"	"12.2"	"9.2"	"4.9"	"5.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HCS7"	"Pre-mRNA-splicing factor SYF1 OS=Homo sapiens OX=9606 GN=XAB2 PE=1 SV=2"	"1"	"1"	"2"	"1"	"855"	"99.9"	"6.23"	"425.90"	"3.43"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes"	"nucleus;other cell component"	""	"Pf13181"	"56949"	"ENSG00000076924"	"XAB2"	"hsa:56949; Q8TET6; Q96HB0; Q96IW0; Q9HCS7; Q9NRG6; Q9ULP3"	"mRNA Splicing - Major Pathway; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	"Rett syndrome causing genes; Nucleotide excision repair in xeroderma pigmentosum"	"7"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UQ35"	"Serine/arginine repetitive matrix protein 2 OS=Homo sapiens OX=9606 GN=SRRM2 PE=1 SV=2"	"1"	"1"	"2"	"1"	"2752"	"299.4"	"12.06"	"507.36"	"3.43"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf08312"	"23524"	"ENSG00000167978"	"SRRM2"	"A6NKB9; D3DU97; hsa:23524; O15038; O94803; Q6NSL3; Q6PIM3; Q6PK40; Q8IW17; Q96GY7; Q9P0G1; Q9UHA8; Q9UQ35; Q9UQ36; Q9UQ37; Q9UQ38; Q9UQ40"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"77.9"	"72.6"	"315.1"	"59.6"	"61.1"	"45.2"	"362.3"	"33.4"	"70.9"	"35.0"	"39.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TEA8"	"D-aminoacyl-tRNA deacylase 1 OS=Homo sapiens OX=9606 GN=DTD1 PE=1 SV=2"	"8"	"1"	"2"	"1"	"209"	"23.4"	"8.24"	"345.54"	"3.43"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02580"	"92675"	"ENSG00000125821"	"DTD1"	"A8K5X5; D3DW37; hsa:92675; Q496D1; Q5W184; Q8TEA8; Q8WXU8; Q9BW67; Q9H464; Q9H474"	""	""	"0"	"0"	"15.1"	"15.2"	"19.2"	"7.7"	"8.7"	"3.7"	"17.5"	"11.0"	"10.3"	"10.2"	"14.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TDN6"	"Ribosome biogenesis protein BRX1 homolog OS=Homo sapiens OX=9606 GN=BRIX1 PE=1 SV=2"	"4"	"1"	"2"	"1"	"353"	"41.4"	"9.92"	"424.72"	"3.43"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf04427"	"55299"	"ENSG00000113460"	"BRIX1"	"A8K0P5; hsa:55299; Q3ZTT4; Q8N453; Q8TDN6; Q96DH1"	""	"Gastric cancer network 2"	"1"	"0"	"55.9"	"47.0"	"144.6"	"56.3"	"56.6"	"43.1"	"146.2"	"21.7"	"39.0"	"29.0"	"27.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WZA0"	"Protein LZIC OS=Homo sapiens OX=9606 GN=LZIC PE=1 SV=1"	"6"	"1"	"2"	"1"	"190"	"21.5"	"4.94"	"327.60"	"3.42"	"1"	"1"	"other biological processes"	""	"other molecular function"	"Pf06384"	"84328"	"ENSG00000162441"	"LZIC"	"B2R6F0; B4E2N0; hsa:84328; Q8WZA0; Q96IU1"	""	""	"0"	"0"	"7.6"	"10.5"	"53.5"	"8.3"	"8.5"	"8.3"	"59.8"	"4.8"	"5.0"	"7.2"	"5.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y320"	"Thioredoxin-related transmembrane protein 2 OS=Homo sapiens OX=9606 GN=TMX2 PE=1 SV=1"	"4"	"1"	"2"	"1"	"296"	"34.0"	"8.69"	"300.10"	"3.41"	"1"	"1"	"developmental processes"	"other membranes;mitochondrion;ER/Golgi;other cell component"	"other molecular function"	"Pf00085"	"51075"	"ENSG00000213593"	"TMX2"	"B7Z4R4; hsa:51075; Q53G73; Q561W0; Q5J7Q7; Q8NBP9; Q9H3L1; Q9Y320"	""	""	"0"	"0"	"38.2"	"30.8"	"150.3"	"29.5"	"33.1"	"20.3"	"122.3"	"15.4"	"17.8"	"17.1"	"15.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQ39"	"ATP-dependent RNA helicase DDX50 OS=Homo sapiens OX=9606 GN=DDX50 PE=1 SV=1"	"3"	"2"	"3"	"2"	"737"	"82.5"	"9.17"	"566.34"	"3.40"	"2"	"1"	""	"plasma membrane;other membranes;nucleus"	"other molecular function"	"Pf00270, Pf00271, Pf08152"	"79009"	"ENSG00000107625"	"DDX50"	"hsa:79009; Q5VX37; Q8WV76; Q9BQ39; Q9BWI8"	""	""	"0"	"0"	"27.9"	"39.7"	"109.6"	"24.9"	"22.2"	"18.2"	"96.9"	"8.2"	"11.7"	"7.9"	"6.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92793"	"CREB-binding protein OS=Homo sapiens OX=9606 GN=CREBBP PE=1 SV=3"	"1"	"1"	"2"	"1"	"2442"	"265.2"	"8.53"	"386.94"	"3.40"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00439, Pf00569, Pf02135, Pf02172, Pf06001, Pf08214, Pf09030"	"1387"	"ENSG00000005339"	"CREBBP"	"D3DUC9; hsa:1387; O00147; Q16376; Q4LE28; Q92793"	"Activation of gene expression by SREBF (SREBP); SUMOylation of transcription cofactors; Formation of paraxial mesoderm; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Pre-NOTCH Transcription and Translation; NOTCH1 Intracellular Domain Regulates Transcription; Notch-HLH transcription pathway; NOTCH3 Intracellular Domain Regulates Transcription; Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells; NOTCH4 Intracellular Domain Regulates Transcription; RUNX3 regulates NOTCH signaling; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Activation of the TFAP2 (AP-2) family of transcription factors; PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; NPAS4 regulates expression of target genes; Heme signaling; Formation of the beta-catenin:TCF transactivating complex; BMAL1:CLOCK,NPAS2 activates circadian gene expression; Transcriptional activation of mitochondrial biogenesis; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Cytoprotection by HMOX1; NFE2L2 regulating anti-oxidant/detoxification enzymes; HATs acetylate histones; TP53 Regulates Transcription of Genes Involved in Cytochrome C Release; Nuclear events mediated by NFE2L2; NFE2L2 regulates pentose phosphate pathway genes; FOXO-mediated transcription of cell death genes; Regulation of FOXO transcriptional activity by acetylation; RORA activates gene expression; Attenuation phase; CD209 (DC-SIGN) signaling; TRAF3-dependent IRF activation pathway; TRAF6 mediated IRF7 activation; Regulation of gene expression by Hypoxia-inducible Factor; RUNX1 regulates transcription of genes involved in differentiation of myeloid cells; LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production"	"Androgen receptor signaling pathway; Angiogenesis; TNF-alpha signaling pathway; Notch signaling; Initiation of transcription and translation elongation at the HIV-1 LTR; IL6 signaling pathway; Pathways affected in adenoid cystic carcinoma; Hematopoietic stem cell gene regulation by GABP alpha/beta complex; VEGFA-VEGFR2 signaling; Wnt signaling pathway and pluripotency; Clear cell renal cell carcinoma pathways; Ebola virus infection in host; Type 2 papillary renal cell carcinoma; Ciliary landscape; Hepatitis B infection; Male infertility; TGF-beta receptor signaling in skeletal dysplasias; Overlap between signal transduction pathways contributing to LMNA laminopathies; 15q13.3 copy number variation syndrome; Urotensin-II-mediated signaling pathway; TGF-beta receptor signaling; Sudden infant death syndrome (SIDS) susceptibility pathways"	"63"	"0"	"9.4"	"12.5"	"47.9"	"14.8"	"11.9"	"8.2"	"53.3"	"8.5"	"11.2"	"8.8"	"13.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43670"	"BUB3-interacting and GLEBS motif-containing protein ZNF207 OS=Homo sapiens OX=9606 GN=ZNF207 PE=1 SV=1"	"3"	"1"	"2"	"1"	"478"	"50.7"	"9.10"	"429.37"	"3.39"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	""	"7756"	"ENSG00000010244"	"ZNF207"	"A8K6Y6; E1P660; E1P661; E1P662; hsa:7756; O43670; Q53XS9; Q96HW5; Q9BUQ7"	""	""	"0"	"0"	"60.3"	"55.4"	"232.9"	"65.3"	"65.8"	"55.6"	"264.9"	"45.0"	"72.0"	"46.9"	"77.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13685"	"Angio-associated migratory cell protein OS=Homo sapiens OX=9606 GN=AAMP PE=1 SV=2"	"3"	"1"	"1"	"1"	"434"	"46.7"	"4.42"	""	"3.39"	""	"1"	"developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00400"	"14"	"ENSG00000127837"	"AAMP"	"hsa:14; Q13685; Q8WUJ9; Q96H92"	"Thromboxane signalling through TP receptor; Signaling by EGFR; NOD1/2 Signaling Pathway; Signaling by VEGF"	"Nucleotide-binding oligomerization domain (NOD) pathway"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"O14967"	"Calmegin OS=Homo sapiens OX=9606 GN=CLGN PE=1 SV=1"	"3"	"1"	"2"	"1"	"610"	"70.0"	"4.69"	"374.91"	"3.39"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf00262"	"1047"	"ENSG00000153132"	"CLGN"	"B3KS90; B4DXV8; D3DNY8; hsa:1047; O14967"	""	""	"0"	"0"	"10.4"	"10.2"	"35.7"	"11.9"	"6.4"	"6.5"	"31.8"	"2.7"	"6.5"	"4.7"	"2.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y570"	"Protein phosphatase methylesterase 1 OS=Homo sapiens OX=9606 GN=PPME1 PE=1 SV=3"	"3"	"1"	"2"	"1"	"386"	"42.3"	"5.97"	"399.08"	"3.39"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes"	"nucleus"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf12697"	"51400"	"ENSG00000214517"	"PPME1"	"B3KMU6; B5MEE7; hsa:51400; J3QT22; Q8WYG8; Q9NVT5; Q9UI18; Q9Y570"	"Cyclin A/B1/B2 associated events during G2/M transition"	""	"1"	"0"	"30.6"	"24.5"	"121.1"	"19.7"	"13.8"	"8.8"	"105.5"	"5.7"	"10.7"	"7.4"	"6.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60568"	"Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 OS=Homo sapiens OX=9606 GN=PLOD3 PE=1 SV=1"	"4"	"2"	"3"	"2"	"738"	"84.7"	"6.05"	"779.78"	"3.39"	"2"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"non-structural extracellular;extracellular matrix;other membranes;ER/Golgi"	"other molecular function"	"Pf03171"	"8985"	"ENSG00000106397"	"PLOD3"	"B2R6W6; hsa:8985; O60568; Q540C3"	"Collagen biosynthesis and modifying enzymes"	"VEGFA-VEGFR2 signaling; IL-18 signaling pathway"	"3"	"0"	"76.0"	"78.7"	"205.3"	"74.3"	"65.5"	"57.9"	"274.5"	"57.9"	"77.5"	"61.4"	"53.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NV70"	"Exocyst complex component 1 OS=Homo sapiens OX=9606 GN=EXOC1 PE=1 SV=4"	"1"	"1"	"2"	"1"	"894"	"101.9"	"6.61"	"421.57"	"3.38"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf09763, Pf15277"	"55763"	"ENSG00000090989"	"EXOC1"	"hsa:55763; Q504V4; Q8WUE7; Q96T15; Q9NV70; Q9NZE4"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"Ciliary landscape"	"4"	"0"	"5.8"	"3.5"	"16.4"	"0.0"	"4.4"	"3.7"	"44.5"	"30.4"	"70.0"	"89.1"	"85.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQP7"	"Mitochondrial genome maintenance exonuclease 1 OS=Homo sapiens OX=9606 GN=MGME1 PE=1 SV=1"	"4"	"1"	"2"	"1"	"344"	"39.4"	"7.68"	"546.88"	"3.38"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response"	"mitochondrion"	"other molecular function"	"Pf12705"	"92667"	"ENSG00000125871"	"MGME1"	"B2RDG5; D3DW29; hsa:92667; Q96SW3; Q9BQP7"	""	"Primary ovarian insufficiency"	"1"	"0"	"11.8"	"17.8"	"38.2"	"11.1"	"15.0"	"12.2"	"44.5"	"9.1"	"19.2"	"15.8"	"20.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52294"	"Importin subunit alpha-5 OS=Homo sapiens OX=9606 GN=KPNA1 PE=1 SV=3"	"3"	"1"	"2"	"1"	"538"	"60.2"	"5.01"	"416.41"	"3.38"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;transport;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00514, Pf01749, Pf16186"	"3836"	"ENSG00000114030"	"KPNA1"	"D3DN93; hsa:3836; P52294; Q6IBQ9; Q9BQ56"	"ISG15 antiviral mechanism; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Vpr-mediated nuclear import of PICs; Apoptosis induced DNA fragmentation; Interferon alpha/beta signaling; Assembly of the ORC complex at the origin of replication; Integration of provirus; Inhibition of nitric oxide production"	"Ebola virus infection in host"	"10"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6IAA8"	"Ragulator complex protein LAMTOR1 OS=Homo sapiens OX=9606 GN=LAMTOR1 PE=1 SV=2"	"8"	"1"	"2"	"1"	"161"	"17.7"	"5.15"	"411.54"	"3.38"	"1"	"1"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;other cytoplasmic organelle"	"other molecular function"	"Pf15454"	"55004"	"ENSG00000149357"	"LAMTOR1"	"hsa:55004; Q6IAA8; Q8WZ09; Q9NWT0"	"Regulation of PTEN gene transcription; mTORC1-mediated signalling; Neutrophil degranulation; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RHOG GTPase cycle; Amino acids regulate mTORC1; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOJ GTPase cycle; TP53 Regulates Metabolic Genes; Macroautophagy; Energy dependent regulation of mTOR by LKB1-AMPK; RHOH GTPase cycle"	"Perturbations to host-cell autophagy, induced by SARS-CoV-2 proteins"	"17"	"0"	"57.8"	"85.2"	"307.5"	"84.1"	"89.1"	"66.6"	"280.0"	"27.9"	"49.0"	"41.0"	"36.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52298"	"Nuclear cap-binding protein subunit 2 OS=Homo sapiens OX=9606 GN=NCBP2 PE=1 SV=1"	"11"	"1"	"2"	"1"	"156"	"18.0"	"8.21"	"306.30"	"3.37"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"22916"	"ENSG00000114503"	"NCBP2"	"B2RE91; B4DMK7; E9PAR5; hsa:22916; P52298; Q14924; Q2TS50"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); mRNA Splicing - Major Pathway; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; snRNP Assembly; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Abortive elongation of HIV-1 transcript in the absence of Tat; RNA Polymerase II Pre-transcription Events; RNA polymerase II transcribes snRNA genes; mRNA Capping; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Signaling by FGFR2 IIIa TM; Processing of Intronless Pre-mRNAs; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"mRNA processing; 3q29 copy number variation syndrome"	"29"	"0"	"10.3"	"11.3"	"23.8"	"8.2"	"10.5"	"9.7"	"36.7"	"5.1"	"8.3"	"11.3"	"7.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5A7"	"NEDD8 ultimate buster 1 OS=Homo sapiens OX=9606 GN=NUB1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"615"	"70.5"	"5.96"	"362.53"	"3.37"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus"	""	"Pf00627, Pf18037"	"51667"	"ENSG00000013374"	"NUB1"	"hsa:51667; O95422; Q75MR9; Q8IX22; Q9BXR2; Q9Y5A7"	""	""	"0"	"0"	"20.3"	"45.9"	"137.8"	"38.7"	"28.6"	"26.5"	"114.6"	"18.9"	"21.2"	"21.7"	"22.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EY5"	"Multivesicular body subunit 12A OS=Homo sapiens OX=9606 GN=MVB12A PE=1 SV=1"	"4"	"1"	"2"	"1"	"273"	"28.8"	"8.91"	"376.49"	"3.37"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf10240"	"93343"	"ENSG00000141971"	"MVB12A"	"hsa:93343; Q96EY5; Q96I18"	"Budding and maturation of HIV virion; Membrane binding and targetting of GAG proteins; Endosomal Sorting Complex Required For Transport (ESCRT); Late endosomal microautophagy; HCMV Late Events"	"7q11.23 copy number variation syndrome"	"6"	"0"	"75.1"	"76.0"	"163.1"	"101.9"	"79.4"	"81.4"	"174.6"	"62.8"	"138.1"	"143.1"	"196.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BZE1"	"39S ribosomal protein L37, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL37 PE=1 SV=2"	"4"	"1"	"2"	"1"	"423"	"48.1"	"8.59"	"333.27"	"3.37"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf07147"	"51253"	"ENSG00000116221"	"MRPL37"	"hsa:51253; Q96Q67; Q9BWR1; Q9BZE1; Q9P0P3"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"51.8"	"64.3"	"178.2"	"55.3"	"41.5"	"47.5"	"186.0"	"23.0"	"44.9"	"33.5"	"39.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86UK7"	"E3 ubiquitin-protein ligase ZNF598 OS=Homo sapiens OX=9606 GN=ZNF598 PE=1 SV=1"	"2"	"1"	"2"	"1"	"904"	"98.6"	"8.40"	"342.81"	"3.37"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus"	"enzyme regulator activity;translation activity;other molecular function"	""	"90850"	""	"ZNF598"	"hsa:90850; Q86UK7; Q8IW49; Q8N3D9; Q96FG3; Q9H7J3"	""	""	"0"	"0"	"36.0"	"35.0"	"128.6"	"35.6"	"40.7"	"26.5"	"114.5"	"13.8"	"26.1"	"24.8"	"23.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q69YN2"	"CWF19-like protein 1 OS=Homo sapiens OX=9606 GN=CWF19L1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"538"	"60.6"	"7.24"	"346.50"	"3.36"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"enzyme regulator activity"	"Pf04676, Pf04677"	"55280"	"ENSG00000095485"	"CWF19L1"	"B4DHX1; D3DR66; hsa:55280; Q5W0I3; Q69YN2; Q96HC3; Q9H865; Q9NV13"	""	""	"0"	"0"	"42.4"	"39.7"	"130.1"	"41.4"	"48.3"	"36.3"	"182.8"	"34.7"	"49.7"	"35.2"	"50.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H5V9"	"UPF0428 protein CXorf56 OS=Homo sapiens OX=9606 GN=CXorf56 PE=1 SV=1"	"9"	"2"	"3"	"2"	"222"	"25.6"	"8.73"	"656.87"	"3.34"	"2"	"1"	"cell organization and biogenesis;transport"	"cytoskeleton;nucleus;other cell component"	""	""	"63932"	"ENSG00000018610"	"STEEP1"	"A8MPX7; B4DQN2; D3DWH9; F5GWL7; hsa:63932; O43351; Q9H5V9"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"172.5"	"210.6"	"466.9"	"185.4"	"215.9"	"176.1"	"595.0"	"142.0"	"232.8"	"209.5"	"223.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y6Y8"	"SEC23-interacting protein OS=Homo sapiens OX=9606 GN=SEC23IP PE=1 SV=1"	"2"	"1"	"2"	"1"	"1000"	"111.0"	"5.54"	"467.07"	"3.34"	"1"	"1"	"cell organization and biogenesis;transport"	"other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00536, Pf02862"	"11196"	"ENSG00000107651"	"SEC23IP"	"D3DRD2; hsa:11196; Q8IXH5; Q9BUK5; Q9Y6Y8"	"COPII-mediated vesicle transport"	""	"1"	"0"	"35.4"	"41.0"	"220.3"	"44.2"	"49.3"	"30.8"	"260.0"	"18.7"	"29.8"	"19.6"	"14.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NRP0"	"Oligosaccharyltransferase complex subunit OSTC OS=Homo sapiens OX=9606 GN=OSTC PE=1 SV=1"	"8"	"1"	"2"	"1"	"149"	"16.8"	"9.13"	"370.19"	"3.34"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;ER/Golgi"	""	"Pf04756"	"58505"	"ENSG00000198856"	"OSTC"	"A8MYS2; B2R5H1; D6RH22; hsa:58505; Q9NRP0; Q9P075; Q9P1R4"	""	""	"0"	"0"	"50.9"	"48.0"	"201.4"	"50.4"	"41.4"	"22.8"	"160.2"	"16.4"	"28.0"	"12.8"	"15.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NFY9"	"Kelch repeat and BTB domain-containing protein 8 OS=Homo sapiens OX=9606 GN=KBTBD8 PE=1 SV=2"	"4"	"2"	"3"	"2"	"601"	"68.8"	"6.29"	"859.88"	"3.34"	"2"	"1"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;other cell component"	""	"Pf00651, Pf01344, Pf07707"	"84541"	"ENSG00000163376"	"KBTBD8"	"B4DTW6; hsa:84541; Q8NFY9; Q96JI5"	"Antigen processing: Ubiquitination & Proteasome degradation; Neddylation"	""	"2"	"0"	"0.0"	"0.0"	"6.4"	"0.0"	"1.6"	"2.6"	"15.5"	"19.4"	"45.8"	"48.3"	"46.4"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UIJ7"	"GTP:AMP phosphotransferase AK3, mitochondrial OS=Homo sapiens OX=9606 GN=AK3 PE=1 SV=4"	"5"	"1"	"2"	"1"	"227"	"25.6"	"9.16"	"340.93"	"3.34"	"1"	"1"	"other metabolic processes;stress response"	"mitochondrion;other cell component"	"kinase activity;other molecular function"	"Pf00406, Pf05191"	"50808"	"ENSG00000147853"	"AK3"	"B4DP58; D3DRI1; E7ET30; hsa:50808; Q5VYW6; Q9H576; Q9HC01; Q9NPB4; Q9UIJ7"	"Factors involved in megakaryocyte development and platelet production"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WWH5"	"Probable tRNA pseudouridine synthase 1 OS=Homo sapiens OX=9606 GN=TRUB1 PE=1 SV=1"	"3"	"1"	"2"	"1"	"349"	"37.2"	"8.25"	"359.90"	"3.33"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01509"	"142940"	"ENSG00000165832"	"TRUB1"	"B2R716; hsa:142940; Q53ES2; Q8WWH5"	""	""	"0"	"0"	"88.3"	"65.0"	"117.5"	"60.1"	"41.2"	"34.5"	"137.9"	"29.1"	"34.5"	"43.1"	"50.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23434"	"Glycine cleavage system H protein, mitochondrial OS=Homo sapiens OX=9606 GN=GCSH PE=1 SV=2"	"6"	"1"	"2"	"1"	"173"	"18.9"	"4.88"	"247.43"	"3.33"	"1"	"1"	"protein metabolism;other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf01597"	"2653"	"ENSG00000140905"	"GCSH"	"hsa:2653; P23434; Q9H1E9"	"Glycine degradation"	""	"2"	"0"	"69.0"	"106.7"	"469.2"	"107.1"	"96.8"	"60.0"	"598.9"	"46.8"	"81.7"	"62.9"	"79.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92552"	"28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3"	"5"	"2"	"3"	"2"	"414"	"47.6"	"6.18"	"834.01"	"3.33"	"2"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf10037"	"23107"	"ENSG00000113048"	"MRPS27"	"B4DRT2; hsa:23107; Q6P1S1; Q92552"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"65.9"	"79.0"	"262.9"	"83.7"	"76.9"	"59.1"	"423.3"	"45.4"	"55.8"	"48.3"	"41.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TDN4"	"CDK5 and ABL1 enzyme substrate 1 OS=Homo sapiens OX=9606 GN=CABLES1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"633"	"67.6"	"9.17"	"392.10"	"3.32"	"1"	"1"	"cell cycle OR cell proliferation;developmental processes;other biological processes"	"cytosol;nucleus"	""	"Pf00134"	"91768"	"ENSG00000134508"	"CABLES1"	"B4DK60; hsa:91768; Q8N3Y8; Q8NA22; Q8TDN4; Q9BTG1"	"Factors involved in megakaryocyte development and platelet production; Cyclin E associated events during G1/S transition ; Cyclin A:Cdk2-associated events at S phase entry"	""	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NR12"	"PDZ and LIM domain protein 7 OS=Homo sapiens OX=9606 GN=PDLIM7 PE=1 SV=1"	"4"	"2"	"3"	"2"	"457"	"49.8"	"8.41"	"582.27"	"3.31"	"2"	"1"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412, Pf00595"	"9260"	"ENSG00000196923"	"PDLIM7"	"hsa:9260; Q14250; Q5XG82; Q6NVZ5; Q96C91; Q9BXB8; Q9BXB9; Q9NR12"	"RET signaling"	"Ebstein-Barr virus LMP1 signaling; GDNF signaling"	"3"	"0"	"100.0"	"124.6"	"252.9"	"102.6"	"98.3"	"94.9"	"353.1"	"108.4"	"144.8"	"99.9"	"113.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q969G6"	"Riboflavin kinase OS=Homo sapiens OX=9606 GN=RFK PE=1 SV=2"	"14"	"1"	"1"	"1"	"155"	"17.6"	"8.13"	""	"3.31"	""	"1"	"other metabolic processes;other biological processes"	"cytosol;mitochondrion;other cell component"	"kinase activity;other molecular function"	"Pf01687"	"55312"	"ENSG00000135002"	"RFK"	"hsa:55312; Q5JSG9; Q969G6; Q9NUT7"	"Vitamin B2 (riboflavin) metabolism"	"Selenium micronutrient network; Folate metabolism; TNF-alpha signaling pathway"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q92556"	"Engulfment and cell motility protein 1 OS=Homo sapiens OX=9606 GN=ELMO1 PE=1 SV=2"	"2"	"2"	"3"	"1"	"727"	"83.8"	"6.28"	"604.82"	"3.30"	"2"	"1"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf04727, Pf11841, Pf16457"	"9844"	"ENSG00000155849"	"ELMO1"	"A4D1X6; hsa:9844; Q29R79; Q6ZTJ0; Q92556; Q96PB0; Q9H0I1"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; VEGFA-VEGFR2 Pathway; PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases; Nef and signal transduction"	"Chemokine signaling pathway; CCL18 signaling pathway"	"7"	"0"	"17.2"	"20.6"	"52.1"	"18.5"	"20.5"	"7.0"	"47.1"	"7.7"	"17.6"	"31.2"	"31.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96MG7"	"Non-structural maintenance of chromosomes element 3 homolog OS=Homo sapiens OX=9606 GN=NSMCE3 PE=1 SV=1"	"4"	"1"	"2"	"1"	"304"	"34.3"	"9.28"	"391.31"	"3.30"	"1"	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf01454"	"56160"	"ENSG00000185115; ENSG00000282130"	"NSMCE3"	"hsa:56160; Q8IW16; Q8TEI6; Q96MG7; Q9H214"	"SUMOylation of DNA damage response and repair proteins"	""	"1"	"0"	"27.1"	"26.4"	"69.6"	"24.6"	"24.6"	"20.0"	"58.9"	"9.4"	"18.7"	"9.8"	"10.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60468"	"Protein transport protein Sec61 subunit beta OS=Homo sapiens OX=9606 GN=SEC61B PE=1 SV=2"	"11"	"1"	"2"	"1"	"96"	"10.0"	"11.56"	"336.91"	"3.30"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;transport"	"other membranes;cytosol;ER/Golgi"	"translation activity;other molecular function"	"Pf03911"	"10952"	"ENSG00000106803"	"SEC61B"	"hsa:10952; P38390; P38391; P60468; Q6IBC1"	"ER-Phagosome pathway; SRP-dependent cotranslational protein targeting to membrane; Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"	""	"3"	"0"	"95.8"	"94.3"	"300.4"	"93.9"	"83.3"	"55.3"	"249.8"	"36.3"	"53.8"	"37.5"	"45.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBQ7"	"Glyoxylate reductase/hydroxypyruvate reductase OS=Homo sapiens OX=9606 GN=GRHPR PE=1 SV=1"	"9"	"2"	"4"	"2"	"328"	"35.6"	"7.39"	"1284.98"	"3.29"	"2"	"1"	"other metabolic processes"	"cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00389, Pf02826"	"9380"	"ENSG00000137106"	"GRHPR"	"hsa:9380; Q5T945; Q9H3E9; Q9H636; Q9UBQ7; Q9UKX1"	"Glyoxylate metabolism and glycine degradation"	""	"1"	"0"	"42.8"	"40.1"	"172.0"	"44.1"	"36.9"	"29.1"	"266.7"	"20.6"	"33.6"	"30.3"	"34.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P17096"	"High mobility group protein HMG-I/HMG-Y OS=Homo sapiens OX=9606 GN=HMGA1 PE=1 SV=3"	"10"	"1"	"2"	"1"	"107"	"11.7"	"10.32"	"456.23"	"3.29"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	""	"3159"	"ENSG00000137309"	"HMGA1"	"hsa:3159; P10910; P17096; Q5T6U9; Q9UKB0"	"Vpr-mediated nuclear import of PICs; 2-LTR circle formation; Integration of viral DNA into host genomic DNA; Autointegration results in viral DNA circles; APOBEC3G mediated resistance to HIV-1 infection; Formation of Senescence-Associated Heterochromatin Foci (SAHF)"	"Adipogenesis; Pre-implantation embryo; Male infertility; 7q11.23 copy number variation syndrome; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Orexin receptor pathway"	"13"	"0"	"66.9"	"54.1"	"159.7"	"66.2"	"75.9"	"65.8"	"589.5"	"120.8"	"268.7"	"215.1"	"154.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96ST3"	"Paired amphipathic helix protein Sin3a OS=Homo sapiens OX=9606 GN=SIN3A PE=1 SV=2"	"1"	"1"	"2"	"1"	"1273"	"145.1"	"7.25"	"420.31"	"3.28"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02671, Pf08295, Pf16879"	"25942"	"ENSG00000169375"	"SIN3A"	"B2RNS5; hsa:25942; Q8N8N4; Q8NC83; Q8WV18; Q96L98; Q96ST3; Q9UFQ1"	"Cytoprotection by HMOX1; Factors involved in megakaryocyte development and platelet production; NoRC negatively regulates rRNA expression; FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes; SUMOylation of transcription cofactors; MECP2 regulates transcription of neuronal ligands; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Regulation of lipid metabolism by PPARalpha; Regulation of MECP2 expression and activity; STAT3 nuclear events downstream of ALK signaling; MECP2 regulates neuronal receptors and channels; Loss of MECP2 binding ability to 5mC-DNA"	"Androgen receptor signaling pathway; Retinoblastoma gene in cancer; MECP2 and associated Rett syndrome; Transcription co-factors SKI and SKIL protein partners; Hedgehog signaling pathway"	"17"	"0"	"18.8"	"24.3"	"75.9"	"15.8"	"15.4"	"10.5"	"118.4"	"7.6"	"12.5"	"7.9"	"7.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N183"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 OS=Homo sapiens OX=9606 GN=NDUFAF2 PE=1 SV=1"	"5"	"1"	"2"	"1"	"169"	"19.8"	"8.97"	"264.12"	"3.28"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf05071"	"91942"	"ENSG00000164182"	"NDUFAF2"	"A8K5I1; hsa:91942; Q8N183"	"Complex I biogenesis"	"SARS-CoV-2 mitochondrial chronic oxidative stress and endothelial dysfunction"	"2"	"0"	"158.2"	"175.1"	"715.6"	"164.5"	"183.0"	"119.3"	"756.8"	"72.7"	"120.3"	"113.2"	"84.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UI26"	"Importin-11 OS=Homo sapiens OX=9606 GN=IPO11 PE=1 SV=1"	"2"	"1"	"2"	"1"	"975"	"112.5"	"5.25"	"387.45"	"3.27"	"1"	"1"	"transport"	"cytosol;nucleus"	"other molecular function"	"Pf03810"	"51194"	"ENSG00000086200"	"IPO11"	"A6NGJ5; B4DZ73; D3DW98; hsa:51194; Q8N5R2; Q9NSJ6; Q9NVB1; Q9UI26"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NYB9"	"Abl interactor 2 OS=Homo sapiens OX=9606 GN=ABI2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"513"	"55.6"	"6.16"	"246.21"	"3.26"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf07815, Pf14604"	"10152"	"ENSG00000138443"	"ABI2"	"B4DSN1; hsa:10152; Q13147; Q13249; Q13801; Q9BV70; Q9NYB9"	"RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; VEGFA-VEGFR2 Pathway"	"Regulation of actin cytoskeleton"	"8"	"0"	"124.5"	"109.2"	"314.7"	"99.5"	"85.7"	"79.2"	"222.9"	"43.3"	"74.1"	"67.2"	"95.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9ULX6"	"A-kinase anchor protein 8-like OS=Homo sapiens OX=9606 GN=AKAP8L PE=1 SV=4"	"2"	"1"	"2"	"1"	"646"	"71.6"	"5.05"	"381.07"	"3.26"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04988"	"26993"	"ENSG00000011243"	"AKAP8L"	"B4DJ74; B5BU90; hsa:26993; O94792; Q96J58; Q9NRQ0; Q9UGM0; Q9ULX6"	"Formation of WDR5-containing histone-modifying complexes"	""	"1"	"0"	"48.0"	"52.6"	"206.2"	"55.4"	"44.1"	"33.9"	"177.2"	"22.5"	"26.1"	"27.2"	"25.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y6A4"	"Cilia- and flagella-associated protein 20 OS=Homo sapiens OX=9606 GN=CFAP20 PE=1 SV=1"	"6"	"1"	"2"	"1"	"193"	"22.8"	"9.76"	"295.43"	"3.26"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	""	"Pf05018"	"29105"	"ENSG00000070761"	"CFAP20"	"hsa:29105; Q9Y6A4"	""	""	"0"	"0"	"37.9"	"37.9"	"154.2"	"43.2"	"32.9"	"26.9"	"184.2"	"22.7"	"35.6"	"30.3"	"36.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N5K1"	"CDGSH iron-sulfur domain-containing protein 2 OS=Homo sapiens OX=9606 GN=CISD2 PE=1 SV=1"	"16"	"2"	"3"	"2"	"135"	"15.3"	"9.61"	"593.93"	"3.26"	"2"	"1"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"other membranes;mitochondrion;ER/Golgi;other cell component"	"other molecular function"	"Pf09360, Pf10660"	"493856"	"ENSG00000145354"	"CISD2"	"hsa:493856; Q7Z3D5; Q8N5K1"	""	""	"0"	"0"	"169.3"	"211.4"	"882.5"	"211.3"	"187.9"	"158.0"	"826.5"	"87.3"	"145.9"	"94.1"	"81.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75323"	"Protein NipSnap homolog 2 OS=Homo sapiens OX=9606 GN=NIPSNAP2 PE=1 SV=1"	"5"	"2"	"3"	"1"	"286"	"33.7"	"9.36"	"624.29"	"3.26"	"2"	"1"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"other membranes;mitochondrion"	""	"Pf07978"	"2631"	"ENSG00000146729"	"NIPSNAP2"	"C9IYJ3; hsa:2631; O43801; O75323; Q53X96"	"RHOJ GTPase cycle; RHOH GTPase cycle"	""	"2"	"0"	"49.0"	"40.2"	"144.8"	"52.4"	"51.9"	"37.0"	"112.5"	"23.2"	"34.6"	"27.5"	"35.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6PJI9"	"GATOR complex protein WDR59 OS=Homo sapiens OX=9606 GN=WDR59 PE=1 SV=2"	"1"	"1"	"2"	"1"	"974"	"109.7"	"7.91"	"451.89"	"3.25"	"1"	"1"	"stress response;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00400, Pf17120"	"79726"	"ENSG00000103091"	"WDR59"	"B3KRC3; hsa:79726; Q6PJI9; Q71RE7; Q96PW5; Q9BSW6; Q9HA43"	"Amino acids regulate mTORC1"	""	"1"	"0"	"10.2"	"9.8"	"37.6"	"10.1"	"10.1"	"7.9"	"24.6"	"9.0"	"9.0"	"5.0"	"6.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UNL2"	"Translocon-associated protein subunit gamma OS=Homo sapiens OX=9606 GN=SSR3 PE=1 SV=1"	"8"	"1"	"2"	"1"	"185"	"21.1"	"9.61"	"354.75"	"3.24"	"1"	"1"	"transport"	"other membranes;ER/Golgi"	""	"Pf07074"	"6747"	"ENSG00000114850"	"SSR3"	"B2R7D0; B4E2P2; D3DNK5; hsa:6747; Q549M4; Q9UNL2"	"SRP-dependent cotranslational protein targeting to membrane"	"VEGFA-VEGFR2 signaling"	"2"	"0"	"45.7"	"34.4"	"111.6"	"40.8"	"38.7"	"37.2"	"107.9"	"20.5"	"61.1"	"56.9"	"74.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P34949"	"Mannose-6-phosphate isomerase OS=Homo sapiens OX=9606 GN=MPI PE=1 SV=2"	"3"	"1"	"2"	"1"	"423"	"46.6"	"5.95"	"289.63"	"3.24"	"1"	"1"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf01238, Pf20511, Pf20512"	"4351"	"ENSG00000178802"	"MPI"	"A8K8K9; hsa:4351; P34949; Q96AB0"	"Synthesis of GDP-mannose; Defective MPI causes MPI-CDG"	"N-glycan biosynthesis"	"3"	"0"	"18.0"	"23.5"	"115.1"	"25.4"	"20.3"	"14.5"	"147.2"	"12.4"	"19.3"	"12.3"	"14.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50552"	"Vasodilator-stimulated phosphoprotein OS=Homo sapiens OX=9606 GN=VASP PE=1 SV=3"	"4"	"1"	"2"	"1"	"380"	"39.8"	"8.94"	"370.79"	"3.23"	"1"	"1"	"cell organization and biogenesis;developmental processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00568, Pf08776"	"7408"	"ENSG00000125753"	"VASP"	"B2RBT9; hsa:7408; P50552; Q6PIZ1; Q93035"	"Generation of second messenger molecules; Signaling by ROBO receptors; Cell-extracellular matrix interactions"	"Integrin-mediated cell adhesion; Focal adhesion"	"5"	"0"	"5.3"	"5.6"	"43.1"	"5.5"	"4.2"	"3.7"	"65.4"	"2.2"	"6.6"	"4.9"	"6.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q969G3"	"SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Homo sapiens OX=9606 GN=SMARCE1 PE=1 SV=2"	"3"	"1"	"2"	"1"	"411"	"46.6"	"4.88"	"284.42"	"3.23"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00505"	"6605"	"ENSG00000073584"	"SMARCE1"	"B3KMC1; B4DFR4; C0IMW4; C0IMW5; C0IMW7; H7C3F6; hsa:6605; O43539; Q969G3"	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; RMTs methylate histone arginines"	"Androgen receptor signaling pathway; Pathways affected in adenoid cystic carcinoma; Tumor suppressor activity of SMARCB1; Thermogenesis"	"6"	"0"	"48.5"	"45.8"	"225.9"	"49.9"	"43.1"	"27.2"	"167.1"	"23.1"	"36.4"	"21.0"	"20.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P37198"	"Nuclear pore glycoprotein p62 OS=Homo sapiens OX=9606 GN=NUP62 PE=1 SV=3"	"3"	"1"	"2"	"1"	"522"	"53.2"	"5.31"	"331.58"	"3.23"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"other membranes;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf05064"	"23636"	"ENSG00000213024"	"NUP62"	"B3KWU5; hsa:23636; P37198; Q503A4; Q6GTM2; Q96C43; Q9NSL1"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; HCMV Late Events; HCMV Early Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Postmitotic nuclear pore complex (NPC) reformation"	"7q11.23 copy number variation syndrome"	"30"	"0"	"7.9"	"9.4"	"77.7"	"10.6"	"14.9"	"5.9"	"63.4"	"3.5"	"4.6"	"3.0"	"2.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12800"	"Alpha-globin transcription factor CP2 OS=Homo sapiens OX=9606 GN=TFCP2 PE=1 SV=2"	"2"	"1"	"2"	"1"	"502"	"57.2"	"5.80"	"296.84"	"3.23"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04516, Pf18016"	"7024"	"ENSG00000135457"	"TFCP2"	"A8K5E9; hsa:7024; Q12800; Q12801; Q9UD75; Q9UD77"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"22.5"	"37.2"	"119.6"	"46.3"	"40.3"	"41.6"	"94.8"	"13.1"	"31.5"	"36.2"	"41.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12824"	"SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 OS=Homo sapiens OX=9606 GN=SMARCB1 PE=1 SV=2"	"4"	"1"	"2"	"1"	"385"	"44.1"	"6.23"	"318.52"	"3.22"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04855"	"6598"	"ENSG00000099956; ENSG00000275837"	"SMARCB1"	"hsa:6598; O75784; O95474; Q12824; Q17S11; Q38GA1; Q76N08; Q9UBH2"	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; RMTs methylate histone arginines"	"Tumor suppressor activity of SMARCB1; Thermogenesis; Modulators of TCR signaling and T cell activation; DYRK1A involvement regarding cell proliferation in brain development; Kleefstra syndrome"	"7"	"0"	"38.3"	"45.1"	"165.7"	"45.1"	"51.7"	"30.2"	"183.6"	"26.8"	"46.6"	"32.6"	"34.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9GZR7"	"ATP-dependent RNA helicase DDX24 OS=Homo sapiens OX=9606 GN=DDX24 PE=1 SV=1"	"1"	"1"	"2"	"1"	"859"	"96.3"	"9.06"	"413.94"	"3.22"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00270, Pf00271"	"57062"	"ENSG00000089737; ENSG00000273761"	"DDX24"	"E7EMJ4; hsa:57062; Q4V9L5; Q9GZR7"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q15813"	"Tubulin-specific chaperone E OS=Homo sapiens OX=9606 GN=TBCE PE=1 SV=1"	"2"	"1"	"2"	"1"	"527"	"59.3"	"6.76"	"324.37"	"3.21"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01302, Pf14560"	"6905"	"ENSG00000282984; ENSG00000284770; ENSG00000285053"	"TBCE"	"A8K8C2; B7Z3P1; hsa:6905; Q15813"	"Post-chaperonin tubulin folding pathway"	""	"1"	"0"	"23.3"	"27.4"	"109.6"	"21.2"	"22.6"	"13.9"	"102.2"	"11.7"	"11.6"	"10.4"	"8.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y223"	"Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase OS=Homo sapiens OX=9606 GN=GNE PE=1 SV=1"	"2"	"1"	"2"	"1"	"722"	"79.2"	"6.80"	"381.72"	"3.21"	"1"	"1"	"cell adhesion;other metabolic processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00480, Pf02350"	"10020"	"ENSG00000159921"	"GNE"	"A6PZH2; A6PZH3; A7UNU7; B2R6E1; B7Z372; B7Z428; D3DRP7; F5H499; H0YFA7; hsa:10020; Q0VA94; Q9Y223"	"Sialic acid metabolism; Defective GNE causes sialuria, NK and IBM2"	""	"2"	"0"	"11.4"	"15.6"	"38.1"	"13.0"	"6.8"	"7.8"	"41.7"	"4.5"	"4.5"	"6.0"	"4.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H0P0"	"Cytosolic 5'-nucleotidase 3A OS=Homo sapiens OX=9606 GN=NT5C3A PE=1 SV=3"	"4"	"1"	"2"	"1"	"336"	"37.9"	"7.12"	"394.71"	"3.21"	"1"	"1"	"other metabolic processes;stress response"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf05822"	"51251"	"ENSG00000122643"	"NT5C3A"	"A8K253; B2RAA5; B8ZZC4; hsa:51251; Q6IPZ1; Q6NXS6; Q7L3G6; Q9H0P0; Q9P0P5; Q9UC42; Q9UC43; Q9UC44; Q9UC45"	""	""	"0"	"0"	"31.3"	"38.7"	"135.7"	"44.1"	"45.4"	"28.6"	"174.6"	"20.0"	"30.3"	"29.1"	"20.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BW92"	"Threonine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=TARS2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"718"	"81.0"	"7.30"	"373.48"	"3.21"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00587, Pf02824, Pf03129, Pf07973"	"80222"	"ENSG00000143374"	"TARS2"	"hsa:80222; Q53GW7; Q96I50; Q9BW92; Q9H9V2"	"Mitochondrial tRNA aminoacylation"	""	"1"	"0"	"47.7"	"39.8"	"179.0"	"47.2"	"46.0"	"27.3"	"165.3"	"17.0"	"25.6"	"31.6"	"18.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51970"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 OS=Homo sapiens OX=9606 GN=NDUFA8 PE=1 SV=3"	"11"	"2"	"3"	"2"	"172"	"20.1"	"7.65"	"549.32"	"3.20"	"2"	"1"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf06747"	"4702"	"ENSG00000119421"	"NDUFA8"	"B1AM93; hsa:4702; P51970; Q9Y6N0"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"5"	"0"	"109.6"	"134.5"	"398.8"	"118.6"	"113.9"	"98.1"	"397.8"	"61.7"	"85.8"	"80.9"	"88.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UGI8"	"Testin OS=Homo sapiens OX=9606 GN=TES PE=1 SV=1"	"3"	"1"	"2"	"1"	"421"	"48.0"	"7.68"	"370.12"	"3.20"	"1"	"1"	"other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00412, Pf06297"	"26136"	"ENSG00000135269"	"TES"	"A4D0U6; hsa:26136; Q9GZQ1; Q9HAJ9; Q9UGI8"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BYD2"	"39S ribosomal protein L9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL9 PE=1 SV=2"	"4"	"1"	"1"	"1"	"267"	"30.2"	"10.08"	""	"3.19"	""	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf01281"	"65005"	"ENSG00000143436"	"MRPL9"	"B2RD99; hsa:65005; Q5SZR2; Q9BSW8; Q9BYD2"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"207.0"	"206.4"	"604.3"	"203.2"	"219.6"	"188.2"	"716.8"	"86.3"	"141.0"	"121.7"	"106.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15120"	"[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial OS=Homo sapiens OX=9606 GN=PDK3 PE=1 SV=1"	"3"	"1"	"2"	"1"	"406"	"46.9"	"8.37"	"296.97"	"3.19"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"mitochondrion;nucleus"	"kinase activity;other molecular function"	"Pf02518, Pf10436"	"5165"	"ENSG00000067992"	"PDK3"	"B4DXG6; hsa:5165; Q15120"	"Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid"	""	"2"	"0"	"69.1"	"77.5"	"170.5"	"87.4"	"67.1"	"58.4"	"198.2"	"63.3"	"101.8"	"114.0"	"136.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49790"	"Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2"	"1"	"2"	"3"	"2"	"1475"	"153.8"	"8.73"	"702.25"	"3.19"	"2"	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00641, Pf08604, Pf10599"	"9972"	"ENSG00000124789"	"NUP153"	"B4DIK2; E7EPX5; F6QR24; hsa:9972; P49790; Q4LE47; Q5T9I7; Q7Z743"	"Nuclear import of Rev protein; HCMV Late Events; HCMV Early Events; Transcriptional regulation by small RNAs; SUMOylation of DNA replication proteins; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses"	""	"28"	"0"	"33.9"	"26.7"	"104.3"	"36.0"	"38.5"	"27.4"	"156.3"	"22.6"	"45.1"	"40.6"	"35.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30626"	"Sorcin OS=Homo sapiens OX=9606 GN=SRI PE=1 SV=1"	"6"	"1"	"2"	"1"	"198"	"21.7"	"5.59"	"332.24"	"3.18"	"1"	"1"	"transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf13405, Pf13833"	"6717"	"ENSG00000075142"	"SRI"	"A8MTH6; B4DKK2; D6W5Q0; hsa:6717; P30626"	"Stimuli-sensing channels; Ion homeostasis; Ion transport by P-type ATPases; Reduction of cytosolic Ca++ levels; Sodium/Calcium exchangers"	""	"5"	"0"	"12.7"	"17.5"	"80.1"	"20.7"	"16.5"	"8.7"	"82.5"	"7.3"	"7.9"	"6.9"	"7.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z7H5"	"Transmembrane emp24 domain-containing protein 4 OS=Homo sapiens OX=9606 GN=TMED4 PE=1 SV=1"	"9"	"2"	"3"	"2"	"227"	"25.9"	"8.28"	"605.96"	"3.18"	"2"	"1"	"cell organization and biogenesis;transport"	"other membranes;ER/Golgi;other cell component"	""	"Pf01105"	"222068"	"ENSG00000158604"	"TMED4"	"A4D2K8; B4DFJ4; hsa:222068; Q56VW3; Q7Z432; Q7Z7H5; Q8N2P6"	""	""	"0"	"0"	"93.5"	"85.0"	"375.0"	"91.5"	"76.7"	"43.7"	"416.3"	"35.9"	"55.3"	"40.1"	"42.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5T750"	"Skin-specific protein 32 OS=Homo sapiens OX=9606 GN=XP32 PE=1 SV=1"	"4"	"1"	"2"	"1"	"250"	"26.2"	"7.97"	"285.65"	"3.18"	"1"	"1"	"other biological processes"	""	""	""	"100129271"	"ENSG00000198854"	"KPLCE"	"hsa:100129271; O14634; Q5T750"	""	""	"0"	"0"	"453.1"	"286.3"	"132.6"	"40.3"	"60.0"	"54.1"	"103.8"	"44.9"	"25.2"	"57.2"	"26.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16527"	"Cysteine and glycine-rich protein 2 OS=Homo sapiens OX=9606 GN=CSRP2 PE=1 SV=3"	"7"	"1"	"2"	"1"	"193"	"20.9"	"8.62"	"399.92"	"3.18"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412"	"1466"	"ENSG00000175183"	"CSRP2"	"hsa:1466; Q16527; Q93030"	""	"Mesodermal commitment pathway; VEGFA-VEGFR2 signaling; H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity"	"3"	"0"	"16.7"	"14.9"	"41.0"	"22.7"	"18.1"	"13.5"	"61.0"	"8.8"	"19.9"	"18.2"	"18.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BZF9"	"Uveal autoantigen with coiled-coil domains and ankyrin repeats OS=Homo sapiens OX=9606 GN=UACA PE=1 SV=2"	"1"	"1"	"2"	"1"	"1416"	"162.4"	"7.03"	"331.17"	"3.18"	"1"	"1"	"other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus"	"cytoskeletal activity"	"Pf12796"	"55075"	"ENSG00000137831"	"UACA"	"G3XAG2; hsa:55075; Q14DD3; Q8N3B8; Q96NH6; Q9BZF9; Q9HCL1; Q9NWC6"	"Regulation of the apoptosome activity; RHOH GTPase cycle"	""	"2"	"0"	"20.6"	"20.7"	"84.9"	"18.4"	"18.9"	"21.3"	"76.5"	"22.5"	"131.9"	"158.4"	"200.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96SB8"	"Structural maintenance of chromosomes protein 6 OS=Homo sapiens OX=9606 GN=SMC6 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1091"	"126.2"	"6.99"	"443.49"	"3.18"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02463"	"79677"	"ENSG00000163029"	"SMC6"	"A8K8Q6; D6W518; hsa:79677; Q05BV4; Q96SB8; Q9H0X3; Q9H6M0"	"SUMOylation of DNA damage response and repair proteins"	""	"1"	"0"	"18.5"	"23.3"	"59.3"	"19.8"	"15.7"	"14.0"	"45.2"	"6.7"	"7.2"	"3.5"	"7.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82932"	"28S ribosomal protein S6, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS6 PE=1 SV=3"	"10"	"1"	"2"	"1"	"125"	"14.2"	"9.26"	"448.57"	"3.17"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf01250"	"64968"	"ENSG00000243927"	"MRPS6"	"B2R573; hsa:64968; P82932; Q96Q64; Q9BSK8; Q9BW89"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"61.1"	"57.8"	"192.1"	"52.8"	"41.9"	"35.9"	"131.7"	"12.1"	"15.3"	"15.6"	"14.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P27144"	"Adenylate kinase 4, mitochondrial OS=Homo sapiens OX=9606 GN=AK4 PE=1 SV=1"	"5"	"1"	"2"	"1"	"223"	"25.3"	"8.40"	"351.37"	"3.17"	"1"	"1"	"other metabolic processes;stress response;other biological processes"	"mitochondrion;other cell component"	"kinase activity;other molecular function"	"Pf00406, Pf05191"	"205"	"ENSG00000162433"	"AK4"	"B2R927; D3DQ62; hsa:205; P27144; Q6IBH4; Q6NXQ5; Q8IUU9"	"Interconversion of nucleotide di- and triphosphates"	"CCL18 signaling pathway"	"2"	"0"	"4.9"	"5.8"	"68.8"	"4.9"	"3.7"	"3.4"	"77.2"	"2.4"	"3.5"	"3.3"	"3.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06132"	"Uroporphyrinogen decarboxylase OS=Homo sapiens OX=9606 GN=UROD PE=1 SV=2"	"3"	"1"	"2"	"1"	"367"	"40.8"	"6.14"	"335.72"	"3.17"	"1"	"1"	"other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf01208"	"7389"	"ENSG00000126088"	"UROD"	"A8K762; hsa:7389; P06132; Q16863; Q16883; Q53YB8; Q53ZP6; Q6IB28; Q9BUZ0"	"Heme biosynthesis"	"Hemesynthesis defects and porphyrias; Heme biosynthesis"	"3"	"0"	"70.8"	"92.3"	"341.3"	"84.8"	"79.2"	"57.1"	"439.5"	"61.5"	"63.7"	"45.6"	"56.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62312"	"U6 snRNA-associated Sm-like protein LSm6 OS=Homo sapiens OX=9606 GN=LSM6 PE=1 SV=1"	"13"	"1"	"2"	"1"	"80"	"9.1"	"9.58"	"358.15"	"3.17"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01423"	"11157"	"ENSG00000164167"	"LSM6"	"hsa:11157; P62312; Q4W5J5; Q9Y4Y8"	"mRNA Splicing - Major Pathway; mRNA decay by 5' to 3' exoribonuclease"	""	"2"	"0"	"97.5"	"137.1"	"389.3"	"89.8"	"94.3"	"63.7"	"474.5"	"57.9"	"91.6"	"52.1"	"52.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NX63"	"MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1"	"8"	"2"	"3"	"2"	"227"	"26.1"	"8.28"	"664.75"	"3.17"	"2"	"1"	"cell organization and biogenesis"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf05300"	"54927"	"ENSG00000106554"	"CHCHD3"	"hsa:54927; Q9NX63"	"Cristae formation; Mitochondrial protein import"	""	"2"	"0"	"101.5"	"115.9"	"496.5"	"88.6"	"80.6"	"47.1"	"521.9"	"30.2"	"59.7"	"37.6"	"36.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NQT4"	"Exosome complex component RRP46 OS=Homo sapiens OX=9606 GN=EXOSC5 PE=1 SV=1"	"6"	"1"	"2"	"1"	"235"	"25.2"	"7.59"	"269.08"	"3.17"	"1"	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01138, Pf03725"	"56915"	"ENSG00000077348"	"EXOSC5"	"hsa:56915; Q32Q81; Q8NG16; Q96I89; Q9NQT4"	"Major pathway of rRNA processing in the nucleolus and cytosol; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	""	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50579"	"Methionine aminopeptidase 2 OS=Homo sapiens OX=9606 GN=METAP2 PE=1 SV=1"	"5"	"1"	"1"	"1"	"478"	"52.9"	"5.82"	""	"3.16"	""	"1"	"protein metabolism;other metabolic processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00557"	"10988"	"ENSG00000111142"	"METAP2"	"B2RDI8; B4DUX5; G3XA91; hsa:10988; P50579; Q8NB11"	"Inactivation, recovery and regulation of the phototransduction cascade"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NW13"	"RNA-binding protein 28 OS=Homo sapiens OX=9606 GN=RBM28 PE=1 SV=3"	"2"	"1"	"2"	"1"	"759"	"85.7"	"9.22"	"290.87"	"3.16"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf00076"	"55131"	"ENSG00000106344"	"RBM28"	"A4D100; B4DU52; E9PDD9; hsa:55131; Q53H65; Q96CV3; Q9NW13"	"Major pathway of rRNA processing in the nucleolus and cytosol"	""	"1"	"0"	"51.2"	"25.3"	"86.0"	"21.3"	"15.1"	"16.1"	"69.9"	"19.0"	"11.0"	"8.5"	"12.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UNH7"	"Sorting nexin-6 OS=Homo sapiens OX=9606 GN=SNX6 PE=1 SV=1"	"4"	"2"	"3"	"2"	"406"	"46.6"	"6.16"	"646.24"	"3.16"	"2"	"1"	"transport;other biological processes"	"other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00787, Pf09325"	"58533"	"ENSG00000129515"	"SNX6"	"C0H5W9; hsa:58533; Q9UNH7; Q9Y449"	""	""	"0"	"0"	"143.8"	"156.3"	"802.0"	"149.0"	"93.2"	"72.5"	"960.1"	"91.4"	"97.5"	"90.5"	"112.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z4H7"	"HAUS augmin-like complex subunit 6 OS=Homo sapiens OX=9606 GN=HAUS6 PE=1 SV=2"	"1"	"1"	"2"	"1"	"955"	"108.6"	"6.47"	"284.82"	"3.15"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton"	"cytoskeletal activity"	"Pf14661"	"54801"	"ENSG00000147874"	"HAUS6"	"B3KPK4; B4DX82; hsa:54801; Q05CG1; Q14CB6; Q14CD9; Q2TA91; Q6IQ10; Q6NZX5; Q7Z4H7; Q8IZQ4; Q96FN0; Q9H950; Q9H998; Q9HCJ8; Q9NXT8"	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	""	"7"	"0"	"28.1"	"26.3"	"102.5"	"25.9"	"20.5"	"14.1"	"83.5"	"6.7"	"12.8"	"10.5"	"10.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQ24"	"Zinc finger FYVE domain-containing protein 21 OS=Homo sapiens OX=9606 GN=ZFYVE21 PE=1 SV=1"	"7"	"1"	"2"	"1"	"234"	"26.5"	"8.41"	"406.01"	"3.15"	"1"	"1"	""	"other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01363, Pf16696"	"79038"	"ENSG00000100711"	"ZFYVE21"	"A8K3A4; hsa:79038; Q86T05; Q96LT1; Q9BQ24"	""	""	"0"	"0"	"13.3"	"15.3"	"37.4"	"14.2"	"11.7"	"9.8"	"58.9"	"13.0"	"20.9"	"28.3"	"47.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BPX3"	"Condensin complex subunit 3 OS=Homo sapiens OX=9606 GN=NCAPG PE=1 SV=1"	"1"	"1"	"2"	"1"	"1015"	"114.3"	"5.59"	"325.81"	"3.15"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf12719"	"64151"	"ENSG00000109805"	"NCAPG"	"hsa:64151; Q3MJE0; Q96SV9; Q9BPX3; Q9BUR3; Q9BVY1; Q9H914; Q9H9Z6; Q9HBI9"	"Condensation of Prometaphase Chromosomes"	""	"1"	"0"	"9.1"	"11.9"	"32.0"	"12.1"	"7.2"	"6.3"	"24.5"	"4.3"	"2.7"	"4.8"	"4.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75175"	"CCR4-NOT transcription complex subunit 3 OS=Homo sapiens OX=9606 GN=CNOT3 PE=1 SV=1"	"2"	"1"	"2"	"1"	"753"	"81.8"	"6.20"	"482.47"	"3.15"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf04065, Pf04153"	"4849"	"ENSG00000088038; ENSG00000273943; ENSG00000274176; ENSG00000274616; ENSG00000274941; ENSG00000275979; ENSG00000276082; ENSG00000277114; ENSG00000277600; ENSG00000277615"	"CNOT3"	"hsa:4849; O75175; Q9NZN7; Q9UF76"	"Deadenylation of mRNA; TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"	""	"2"	"0"	"19.8"	"23.1"	"116.1"	"23.7"	"23.1"	"11.0"	"101.1"	"16.7"	"23.6"	"15.2"	"12.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H1E5"	"Thioredoxin-related transmembrane protein 4 OS=Homo sapiens OX=9606 GN=TMX4 PE=1 SV=1"	"4"	"1"	"2"	"1"	"349"	"38.9"	"4.37"	"403.65"	"3.14"	"1"	"1"	""	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf00085"	"56255"	"ENSG00000125827"	"TMX4"	"hsa:56255; Q8N4P7; Q8NCC1; Q9H1E5; Q9UJA1; Q9ULQ8"	""	""	"0"	"0"	"8.9"	"11.6"	"63.8"	"14.4"	"7.2"	"4.8"	"80.8"	"5.9"	"6.8"	"7.5"	"3.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35219"	"Carbonic anhydrase-related protein OS=Homo sapiens OX=9606 GN=CA8 PE=1 SV=3"	"7"	"1"	"2"	"1"	"290"	"33.0"	"4.86"	"445.50"	"3.13"	"1"	"1"	"signal transduction"	"other cell component"	"other molecular function"	"Pf00194"	"767"	"ENSG00000178538"	"CA8"	"A8K0A5; B3KQZ7; hsa:767; P35219; Q32MY2"	""	"PKC-gamma calcium signaling pathway in ataxia"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9Y6D9"	"Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"718"	"83.0"	"5.92"	"265.75"	"3.13"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf05557"	"8379"	"ENSG00000002822"	"MAD1L1"	"B3KR41; hsa:8379; Q13312; Q75MI0; Q86UM4; Q9UNH0; Q9Y6D9"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"Cell cycle; Regulation of sister chromatid separation at the metaphase-anaphase transition; Pleural mesothelioma; CCL18 signaling pathway"	"10"	"0"	"45.8"	"48.9"	"155.9"	"58.9"	"50.6"	"44.6"	"147.3"	"29.1"	"42.0"	"33.7"	"42.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9C0B0"	"RING finger protein unkempt homolog OS=Homo sapiens OX=9606 GN=UNK PE=1 SV=2"	"1"	"1"	"2"	"1"	"810"	"88.0"	"6.86"	"381.69"	"3.13"	"1"	"1"	"developmental processes;other biological processes"	"other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00642, Pf18384"	"85451"	"ENSG00000132478"	"UNK"	"hsa:85451; Q9C0B0"	""	""	"0"	"0"	"12.8"	"11.7"	"33.3"	"9.4"	"7.9"	"9.1"	"49.6"	"4.9"	"10.1"	"9.3"	"8.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16512"	"Serine/threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"942"	"103.9"	"6.37"	"279.32"	"3.13"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00433, Pf02185"	"5585"	"ENSG00000123143"	"PKN1"	"A8K7W5; B2R9R4; B3KVN3; hsa:5585; Q15143; Q16512; Q504U4; Q8IUV5; Q9UD44"	"RHOC GTPase cycle; RHOA GTPase cycle; RAC1 GTPase cycle; RHOB GTPase cycle; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3"	"Apoptosis-related network due to altered Notch3 in ovarian cancer; PI3K-Akt signaling pathway; IL-18 signaling pathway; G13 signaling pathway"	"10"	"0"	"18.9"	"29.5"	"97.1"	"24.5"	"29.1"	"23.1"	"104.3"	"10.8"	"22.1"	"19.3"	"20.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75880"	"Protein SCO1 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=SCO1 PE=1 SV=1"	"6"	"1"	"1"	"1"	"301"	"33.8"	"8.88"	""	"3.13"	""	"1"	"cell organization and biogenesis;other biological processes"	"other membranes;cytoskeleton;mitochondrion"	"other molecular function"	"Pf02630"	"6341"	"ENSG00000133028"	"SCO1"	"B2RDM0; hsa:6341; O75880"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"Electron transport chain: OXPHOS system in mitochondria; Copper homeostasis"	"5"	"0"	"57.7"	"76.8"	"298.9"	"59.8"	"50.5"	"29.9"	"335.4"	"30.1"	"41.1"	"34.9"	"29.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75935"	"Dynactin subunit 3 OS=Homo sapiens OX=9606 GN=DCTN3 PE=1 SV=1"	"6"	"1"	"2"	"1"	"186"	"21.1"	"5.47"	"371.43"	"3.13"	"1"	"1"	"cell cycle OR cell proliferation;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf07426"	"11258"	"ENSG00000137100"	"DCTN3"	"A6NII7; B2RBM5; hsa:11258; O75935; Q5T1I5; Q5T1I7; Q5T8G3; Q9BPU8"	"MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Recruitment of NuMA to mitotic centrosomes; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	""	"11"	"0"	"15.0"	"18.9"	"50.9"	"13.9"	"15.3"	"12.7"	"28.9"	"3.7"	"5.8"	"3.8"	"6.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62993"	"Growth factor receptor-bound protein 2 OS=Homo sapiens OX=9606 GN=GRB2 PE=1 SV=1"	"6"	"1"	"2"	"1"	"217"	"25.2"	"6.32"	"286.59"	"3.13"	"1"	"1"	"cell organization and biogenesis;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00017, Pf00018"	"2885"	"ENSG00000177885"	"GRB2"	"hsa:2885; P29354; P62993; Q14450; Q63057; Q63059"	"Signaling by ALK fusions and activated point mutants; Signaling by CSF3 (G-CSF); STAT5 activation downstream of FLT3 ITD mutants; Interleukin-15 signaling"	"IL-5 signaling pathway; Integrin-mediated cell adhesion; Leptin signaling pathway; Prolactin signaling pathway; IL-9 signaling pathway; Pilocytic astrocytoma; Glioblastoma signaling pathways; Androgen receptor network in prostate cancer; B cell receptor signaling pathway; TNF-alpha signaling pathway; Interleukin-11 signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Alpha 6 beta 4 signaling pathway; IL-3 signaling pathway; Kit receptor signaling pathway; Focal adhesion; Hepatocyte growth factor receptor signaling; RAC1/PAK1/p38/MMP2 pathway; IL6 signaling pathway; Hepatitis C and hepatocellular carcinoma; BDNF-TrkB signaling; Physico-chemical features and toxicity-associated pathways; MAPK signaling pathway; T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Embryonic stem cell pluripotency pathways; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; IL-4 signaling pathway; p38 MAPK signaling pathway; Endometrial cancer; PI3K-Akt signaling pathway; MAPK cascade; Ras signaling; Epithelial to mesenchymal transition in colorectal cancer; Breast cancer pathway; Thermogenesis; EGF/EGFR signaling pathway; Envelope proteins and their potential roles in EDMD physiopathology; Fragile X syndrome; Gastrin signaling pathway; Hepatitis B infection; Melanoma; Thyroid hormones production and peripheral downstream signaling effects; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; IL-2 signaling pathway; 7q11.23 copy number variation syndrome; 16p11.2 distal deletion syndrome; Modulators of TCR signaling and T cell activation; Kallmann syndrome; Pleural mesothelioma; Congenital generalized lipodystrophy; GDNF signaling; 2q13 copy number variation syndrome; A network map of Macrophage-stimulating protein (MSP) signaling; EPO receptor signaling; ErbB signaling pathway; T-cell receptor signaling pathway; DNA damage response (only ATM dependent)"	"66"	"0"	"24.1"	"38.6"	"140.4"	"33.9"	"37.0"	"31.9"	"174.0"	"27.3"	"50.2"	"36.7"	"28.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HB21"	"Pleckstrin homology domain-containing family A member 1 OS=Homo sapiens OX=9606 GN=PLEKHA1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"404"	"45.5"	"8.56"	"394.31"	"3.12"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00169"	"59338"	"ENSG00000107679"	"PLEKHA1"	"B3KQ55; D3DRE2; hsa:59338; Q9BVK0; Q9HB21"	"Synthesis of PIPs at the plasma membrane"	""	"1"	"0"	"5.7"	"4.1"	"8.8"	"0.0"	"2.4"	"3.4"	"20.0"	"5.5"	"26.0"	"64.3"	"129.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EL2"	"28S ribosomal protein S24, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS24 PE=1 SV=1"	"8"	"1"	"2"	"1"	"167"	"19.0"	"9.38"	"458.40"	"3.12"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf14955"	"64951"	"ENSG00000062582"	"MRPS24"	"A4D1U9; hsa:64951; P82668; Q96EL2; Q96Q23; Q9P047"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9BVS5"	"tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=TRMT61B PE=1 SV=2"	"3"	"1"	"2"	"1"	"477"	"52.9"	"6.62"	"312.84"	"3.12"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf08704"	"55006"	"ENSG00000171103"	"TRMT61B"	"hsa:55006; Q9BVS5; Q9H0Q9; Q9NWS7"	"tRNA modification in the mitochondrion"	""	"1"	"0"	"4.6"	"4.6"	"10.8"	"2.9"	"6.1"	"4.4"	"12.0"	"2.5"	"22.3"	"31.9"	"16.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96J01"	"THO complex subunit 3 OS=Homo sapiens OX=9606 GN=THOC3 PE=1 SV=1"	"3"	"1"	"2"	"1"	"351"	"38.7"	"6.09"	"393.88"	"3.12"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00400, Pf08662, Pf12894"	"84321"	"ENSG00000051596"	"THOC3"	"hsa:84321; Q6NZ53; Q96J01"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	""	"3"	"0"	"85.8"	"95.0"	"381.7"	"107.4"	"85.4"	"91.0"	"365.9"	"45.5"	"68.9"	"52.9"	"68.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BX40"	"Protein LSM14 homolog B OS=Homo sapiens OX=9606 GN=LSM14B PE=1 SV=1"	"4"	"2"	"3"	"1"	"385"	"42.0"	"9.69"	"520.78"	"3.11"	"2"	"1"	"other biological processes"	"other cell component"	"nucleic acid binding activity"	"Pf09532, Pf12701"	"149986"	"ENSG00000149657"	"LSM14B"	"hsa:149986; Q6PFW8; Q96LH8; Q9BX40"	""	""	"0"	"0"	"47.1"	"48.9"	"164.0"	"62.7"	"54.3"	"46.5"	"183.7"	"30.4"	"61.0"	"39.7"	"33.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y6M9"	"NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 OS=Homo sapiens OX=9606 GN=NDUFB9 PE=1 SV=3"	"9"	"1"	"2"	"1"	"179"	"21.8"	"8.38"	"473.59"	"3.11"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity"	"Pf05347"	"4715"	"ENSG00000147684"	"NDUFB9"	"B2R8M6; hsa:4715; Q9UQE8; Q9Y6M9"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial immune response to SARS-CoV-2; Oxidative phosphorylation"	"6"	"0"	"95.1"	"39.2"	"216.7"	"87.2"	"34.5"	"27.4"	"122.5"	"15.7"	"27.4"	"21.7"	"17.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55039"	"Developmentally-regulated GTP-binding protein 2 OS=Homo sapiens OX=9606 GN=DRG2 PE=1 SV=1"	"3"	"1"	"2"	"1"	"364"	"40.7"	"8.88"	"256.28"	"3.10"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01926, Pf02824, Pf16897"	"1819"	"ENSG00000108591"	"DRG2"	"B2R8G5; hsa:1819; P55039; Q53Y50; Q9BWB2"	""	""	"0"	"0"	"15.7"	"18.1"	"64.5"	"17.0"	"11.8"	"7.4"	"65.8"	"6.9"	"12.7"	"8.5"	"5.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14320"	"Protein FAM50A OS=Homo sapiens OX=9606 GN=FAM50A PE=1 SV=2"	"2"	"1"	"2"	"1"	"339"	"40.2"	"6.83"	"319.62"	"3.10"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	"Pf04921"	"9130"	"ENSG00000071859"	"FAM50A"	"A8KAQ4; B2R997; hsa:9130; Q14320; Q5HY37; Q6PJH5"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"98.5"	"109.5"	"445.0"	"124.1"	"116.3"	"84.1"	"596.0"	"74.0"	"127.8"	"107.5"	"111.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01831"	"DNA repair protein complementing XP-C cells OS=Homo sapiens OX=9606 GN=XPC PE=1 SV=4"	"2"	"1"	"2"	"1"	"940"	"105.9"	"8.90"	"414.46"	"3.10"	"1"	"1"	"cell cycle OR cell proliferation;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03835, Pf10403, Pf10404, Pf10405"	"7508"	"ENSG00000154767"	"XPC"	"B4DIP3; E9PB96; E9PH69; hsa:7508; Q01831; Q53GT7; Q96AX0"	"SUMOylation of DNA damage response and repair proteins; Formation of Incision Complex in GG-NER; DNA Damage Recognition in GG-NER"	"Male infertility; Nucleotide excision repair; DNA repair pathways, full network; p53 transcriptional gene network; Nucleotide excision repair in xeroderma pigmentosum"	"8"	"0"	"9.5"	"10.9"	"30.8"	"6.5"	"8.1"	"10.5"	"37.3"	"7.2"	"9.9"	"7.0"	"9.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60925"	"Prefoldin subunit 1 OS=Homo sapiens OX=9606 GN=PFDN1 PE=1 SV=2"	"9"	"1"	"2"	"1"	"122"	"14.2"	"6.81"	"406.76"	"3.10"	"1"	"1"	"other biological processes"	"other cell component"	"other molecular function"	"Pf01920"	"5201"	"ENSG00000113068"	"PFDN1"	"B2RD02; hsa:5201; O60925; Q53F95; Q96EX6"	"Prefoldin mediated transfer of substrate  to CCT/TriC"	"Cellular proteostasis; 11p11.2 copy number variation syndrome"	"3"	"0"	"69.0"	"93.5"	"268.1"	"77.0"	"91.6"	"64.1"	"357.5"	"60.8"	"89.5"	"60.2"	"56.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5K5"	"Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3"	"3"	"1"	"2"	"1"	"329"	"37.6"	"5.33"	"344.10"	"3.10"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf01088, Pf18031"	"51377"	"ENSG00000116750"	"UCHL5"	"hsa:51377; Q5LJA6; Q5LJA7; Q8TBS4; Q96BJ9; Q9H1W5; Q9P0I3; Q9UQN2; Q9Y5K5"	"UCH proteinases; Downregulation of TGF-beta receptor signaling"	""	"2"	"0"	"28.2"	"40.0"	"197.1"	"30.5"	"40.1"	"32.0"	"142.7"	"12.9"	"18.5"	"16.7"	"25.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H583"	"HEAT repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=HEATR1 PE=1 SV=3"	"1"	"1"	"2"	"1"	"2144"	"242.2"	"6.54"	"396.39"	"3.09"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity"	"Pf08146, Pf12397"	"55127"	"ENSG00000119285"	"HEATR1"	"hsa:55127; Q5T3Q8; Q6P197; Q9H583; Q9NW23"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	"15.6"	"12.0"	"52.4"	"12.6"	"9.3"	"6.6"	"38.7"	"4.9"	"8.0"	"4.9"	"7.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q06787"	"Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1"	"1"	"1"	"2"	"1"	"632"	"71.1"	"7.42"	"232.25"	"3.09"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"cytoskeletal activity;translation activity;nucleic acid binding activity;other molecular function"	"Pf00013, Pf05641, Pf12235, Pf16098, Pf17904, Pf18336"	"2332"	"ENSG00000102081"	"FMR1"	"A6NNH4; D3DWT0; D3DWT1; D3DWT2; G8JL90; hsa:2332; Q06787; Q16578; Q5PQZ6; Q99054"	""	"Ovarian infertility; Serotonin and anxiety; Fragile X syndrome; Disruption of postsynaptic signaling by CNV; 15q11.2 copy number variation syndrome; Primary ovarian insufficiency"	"6"	"0"	"83.7"	"90.1"	"268.4"	"69.3"	"76.9"	"63.6"	"348.5"	"64.0"	"84.5"	"62.8"	"56.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96SU4"	"Oxysterol-binding protein-related protein 9 OS=Homo sapiens OX=9606 GN=OSBPL9 PE=1 SV=2"	"3"	"2"	"3"	"2"	"736"	"83.1"	"6.18"	"665.43"	"3.09"	"2"	"1"	"other metabolic processes;transport"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf00169, Pf01237"	"114883"	"ENSG00000117859"	"OSBPL9"	"B1AKJ8; B3KPQ4; D3DQ31; hsa:114883; Q5TFC0; Q6IA67; Q86YQ3; Q8NB17; Q8TAS8; Q96SK4; Q96SU4; Q9H9X2"	"Synthesis of bile acids and bile salts"	""	"1"	"0"	"72.7"	"80.8"	"239.5"	"82.9"	"89.0"	"73.1"	"253.2"	"51.7"	"80.5"	"56.7"	"60.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12846"	"Syntaxin-4 OS=Homo sapiens OX=9606 GN=STX4 PE=1 SV=2"	"4"	"1"	"2"	"1"	"297"	"34.2"	"6.28"	"244.58"	"3.09"	"1"	"1"	"cell organization and biogenesis;stress response;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00804, Pf05739"	"6810"	"ENSG00000103496"	"STX4"	"A8MXY0; hsa:6810; Q12846; Q15525; Q6FHE8"	"ER-Phagosome pathway; Translocation of SLC2A4 (GLUT4) to the plasma membrane; trans-Golgi Network Vesicle Budding; Disinhibition of SNARE formation; Other interleukin signaling"	"Insulin signaling"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q14677"	"Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1"	"1"	"1"	"2"	"1"	"625"	"68.2"	"6.42"	"322.45"	"3.08"	"1"	"1"	"transport"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01417"	"9685"	"ENSG00000113282"	"CLINT1"	"B7Z6F8; D3DQJ6; hsa:9685; Q14677; Q8NAF1; Q96E05"	"Golgi Associated Vesicle Biogenesis"	""	"1"	"0"	"237.8"	"258.0"	"790.2"	"218.9"	"177.1"	"153.4"	"918.5"	"85.1"	"150.9"	"98.9"	"83.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9GZU8"	"PSME3-interacting protein OS=Homo sapiens OX=9606 GN=PSME3IP1 PE=1 SV=1"	"4"	"1"	"2"	"1"	"254"	"28.9"	"5.45"	"257.66"	"3.08"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	""	"Pf10187"	"80011"	"ENSG00000172775"	"PSME3IP1"	"hsa:80011; Q9GZU8"	""	""	"0"	"0"	"67.6"	"93.1"	"322.2"	"97.7"	"116.6"	"120.4"	"541.6"	"81.4"	"117.1"	"82.6"	"77.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N983"	"39S ribosomal protein L43, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL43 PE=1 SV=1"	"6"	"1"	"2"	"1"	"215"	"23.4"	"8.65"	"331.68"	"3.07"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf05047"	"84545"	"ENSG00000055950"	"MRPL43"	"B1AL06; B1AL07; B1AL09; B1AL10; C9J5Q3; D3DR71; hsa:84545; Q5JW06; Q7Z719; Q7Z7H6; Q86XN1; Q8N983; Q9BYC7"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"9.0"	"10.8"	"30.5"	"8.3"	"14.0"	"9.0"	"31.9"	"7.1"	"8.3"	"24.6"	"11.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13984"	"General transcription factor IIF subunit 2 OS=Homo sapiens OX=9606 GN=GTF2F2 PE=1 SV=2"	"9"	"2"	"3"	"2"	"249"	"28.4"	"9.23"	"627.69"	"3.07"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf02270, Pf17683"	"2963"	"ENSG00000188342"	"GTF2F2"	"A6NNS5; hsa:2963; P13984; Q5W0H3"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; Viral Messenger RNA Synthesis; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; mRNA Splicing - Major Pathway; Estrogen-dependent gene expression; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM"	"Eukaryotic transcription initiation"	"33"	"0"	"83.3"	"80.6"	"262.3"	"81.6"	"79.4"	"72.2"	"271.6"	"41.5"	"85.7"	"90.4"	"106.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6UWP8"	"Suprabasin OS=Homo sapiens OX=9606 GN=SBSN PE=1 SV=2"	"6"	"1"	"2"	"1"	"590"	"60.5"	"7.01"	"350.65"	"3.07"	"1"	"1"	""	""	""	""	"374897"	"ENSG00000189001"	"SBSN"	"A8K5J0; E9PBV3; hsa:374897; Q6UWP8"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q96DH6"	"RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1"	"5"	"1"	"2"	"1"	"328"	"35.2"	"8.48"	"330.60"	"3.07"	"1"	"1"	"developmental processes;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"124540"	"ENSG00000153944"	"MSI2"	"hsa:124540; Q7Z6M7; Q8N9T4; Q96DH6"	"RHOBTB2 GTPase cycle"	""	"1"	"0"	"51.1"	"54.6"	"199.0"	"60.8"	"73.6"	"50.4"	"259.4"	"27.6"	"54.0"	"38.8"	"36.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75689"	"Arf-GAP with dual PH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ADAP1 PE=1 SV=2"	"3"	"1"	"2"	"1"	"374"	"43.4"	"8.97"	"370.41"	"3.07"	"1"	"1"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf01412"	"11033"	"ENSG00000105963"	"ADAP1"	"A4D2Q2; B3KRZ4; B4DVA6; F6XZ68; H7C2Q4; hsa:11033; O75689"	"Nuclear signaling by ERBB4"	""	"1"	"0"	"19.9"	"20.3"	"70.0"	"20.7"	"30.0"	"15.9"	"89.2"	"22.8"	"66.6"	"137.3"	"167.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96C19"	"EF-hand domain-containing protein D2 OS=Homo sapiens OX=9606 GN=EFHD2 PE=1 SV=1"	"5"	"1"	"2"	"1"	"240"	"26.7"	"5.20"	"422.33"	"3.06"	"1"	"1"	""	"other membranes"	"other molecular function"	"Pf13499"	"79180"	"ENSG00000142634"	"EFHD2"	"hsa:79180; Q5JYW9; Q96C19"	"RHOD GTPase cycle"	""	"1"	"0"	"37.7"	"50.5"	"182.9"	"37.9"	"29.9"	"22.5"	"184.7"	"14.4"	"18.4"	"21.5"	"19.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49916"	"DNA ligase 3 OS=Homo sapiens OX=9606 GN=LIG3 PE=1 SV=2"	"2"	"2"	"3"	"2"	"1009"	"112.8"	"9.01"	"590.15"	"3.06"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00645, Pf01068, Pf04675, Pf04679, Pf16759"	"3980"	"ENSG00000005156"	"LIG3"	"E5KLB5; E5KLB6; hsa:3980; P49916; Q16714; Q6NVK3"	"HDR through MMEJ (alt-NHEJ); Gap-filling DNA repair synthesis and ligation in TC-NER; Gap-filling DNA repair synthesis and ligation in GG-NER; APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway; Resolution of AP sites via the single-nucleotide replacement pathway"	"Base excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; 17q12 copy number variation syndrome"	"9"	"0"	"47.1"	"57.1"	"196.9"	"41.6"	"35.2"	"34.1"	"262.1"	"26.3"	"49.6"	"73.0"	"130.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95983"	"Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1"	"4"	"1"	"2"	"1"	"291"	"32.8"	"5.34"	"387.12"	"3.06"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01429, Pf14048, Pf16564"	"53615"	"ENSG00000071655"	"MBD3"	"A8K4B7; D6W5Z2; hsa:53615; O95983; Q6PIL9; Q6PJZ9; Q86XF4"	"Potential therapeutics for SARS; Regulation of PTEN gene transcription; HDACs deacetylate histones; RNA Polymerase I Transcription Initiation; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of TP53 Activity through Acetylation"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"7"	"0"	"58.4"	"67.8"	"171.7"	"43.2"	"42.7"	"33.4"	"221.5"	"28.8"	"36.6"	"25.0"	"35.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NUP7"	"tRNA:m(4)X modification enzyme TRM13 homolog OS=Homo sapiens OX=9606 GN=TRMT13 PE=1 SV=2"	"2"	"1"	"2"	"1"	"481"	"54.2"	"8.09"	"380.62"	"3.05"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	""	"other molecular function"	"Pf05206, Pf05253, Pf11722"	"54482"	"ENSG00000122435"	"TRMT13"	"hsa:54482; Q5VVL0; Q9NUP7; Q9NW65"	"tRNA modification in the nucleus and cytosol"	""	"1"	"0"	"10.1"	"8.6"	"43.4"	"10.2"	"9.2"	"5.0"	"32.9"	"3.3"	"3.4"	"3.3"	"4.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16850"	"Lanosterol 14-alpha demethylase OS=Homo sapiens OX=9606 GN=CYP51A1 PE=1 SV=3"	"3"	"1"	"2"	"1"	"503"	"56.8"	"8.53"	"389.99"	"3.05"	"1"	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"21.1"	"22.2"	"93.0"	"15.7"	"22.6"	"17.6"	"104.6"	"11.2"	"18.1"	"10.8"	"12.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N1B4"	"Vacuolar protein sorting-associated protein 52 homolog OS=Homo sapiens OX=9606 GN=VPS52 PE=1 SV=1"	"2"	"1"	"2"	"1"	"723"	"82.2"	"5.99"	"318.22"	"3.05"	"1"	"1"	"transport;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf04129"	"6293"	"ENSG00000206286; ENSG00000223501; ENSG00000224455; ENSG00000225590; ENSG00000228425; ENSG00000236014"	"VPS52"	"A2BF38; B0UZZ4; B4DNI9; hsa:6293; Q53GR4; Q5JPA0; Q5SQW1; Q8IUN6; Q8N1B4; Q9NPT5"	"Retrograde transport at the Trans-Golgi-Network"	""	"1"	"0"	"11.7"	"10.2"	"46.3"	"9.0"	"8.5"	"6.9"	"48.5"	"0.0"	"5.5"	"6.0"	"3.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BSG0"	"Protease-associated domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PRADC1 PE=1 SV=1"	"6"	"1"	"2"	"1"	"188"	"21.0"	"5.47"	"387.18"	"3.05"	"1"	"1"	""	"non-structural extracellular"	""	"Pf02225"	"84279"	"ENSG00000135617"	"PRADC1"	"hsa:84279; Q2Z1P2; Q9BSG0"	""	""	"0"	"0"	"18.5"	"21.1"	"41.0"	"20.8"	"20.9"	"23.1"	"29.0"	"12.8"	"15.0"	"8.2"	"11.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BUK0"	"Coiled-coil-helix-coiled-coil-helix domain-containing protein 7 OS=Homo sapiens OX=9606 GN=CHCHD7 PE=1 SV=1"	"12"	"1"	"3"	"1"	"85"	"10.1"	"8.82"	"558.05"	"3.05"	"1"	"1"	"cell organization and biogenesis"	"mitochondrion"	""	""	"79145"	"ENSG00000170791"	"CHCHD7"	"A8K223; E9PBH3; hsa:79145; J3KNE9; Q7Z588; Q9BUK0"	"Mitochondrial protein import"	""	"1"	"0"	"10.5"	"15.5"	"12.0"	"9.8"	"7.9"	"5.3"	"54.4"	"14.7"	"15.5"	"9.8"	"16.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15212"	"Prefoldin subunit 6 OS=Homo sapiens OX=9606 GN=PFDN6 PE=1 SV=1"	"17"	"3"	"5"	"3"	"129"	"14.6"	"8.88"	"1164.67"	"3.05"	"3"	"1"	"cell organization and biogenesis;other biological processes"	"other cell component"	"other molecular function"	"Pf01920"	"10471"	"ENSG00000204220; ENSG00000206283; ENSG00000224782; ENSG00000235692; ENSG00000237335"	"PFDN6"	"hsa:10471; O15212"	"Prefoldin mediated transfer of substrate  to CCT/TriC"	"Cellular proteostasis"	"2"	"0"	"207.6"	"235.3"	"926.7"	"253.7"	"216.4"	"190.3"	"1165.6"	"177.4"	"244.3"	"169.2"	"191.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52565"	"Rho GDP-dissociation inhibitor 1 OS=Homo sapiens OX=9606 GN=ARHGDIA PE=1 SV=3"	"5"	"1"	"2"	"1"	"204"	"23.2"	"5.11"	"315.41"	"3.04"	"1"	"1"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity"	"Pf02115"	"396"	"ENSG00000141522"	"ARHGDIA"	"A8MXW0; B2R5X1; B4DDD3; B4DUV9; hsa:396; P52565; Q6IBM5"	"CDC42 GTPase cycle; RHOC GTPase cycle; RHOA GTPase cycle; RAC1 GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RHOH GTPase cycle; Axonal growth stimulation; Axonal growth inhibition (RHOA activation)"	"Ciliary landscape; Nephrotic syndrome"	"11"	"0"	"60.0"	"49.9"	"394.8"	"64.8"	"48.0"	"37.7"	"430.4"	"34.7"	"42.3"	"23.8"	"30.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N1F7"	"Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2"	"4"	"3"	"4"	"3"	"819"	"93.4"	"5.72"	"760.51"	"3.04"	"3"	"1"	"cell organization and biogenesis;other metabolic processes;transport;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus"	"other molecular function"	"Pf04097"	"9688"	"ENSG00000102900"	"NUP93"	"B3KPQ8; hsa:9688; Q14705; Q8N1F7"	"Regulation of HSF1-mediated heat shock response; HCMV Early Events; Transport of Mature mRNA derived from an Intron-Containing Transcript; HCMV Late Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Postmitotic nuclear pore complex (NPC) reformation"	""	"29"	"0"	"73.4"	"79.5"	"220.6"	"74.3"	"69.6"	"53.2"	"259.5"	"37.8"	"57.4"	"51.8"	"57.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00442"	"RNA 3'-terminal phosphate cyclase OS=Homo sapiens OX=9606 GN=RTCA PE=1 SV=1"	"5"	"2"	"3"	"2"	"366"	"39.3"	"7.85"	"555.72"	"3.04"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf01137, Pf05189"	"8634"	"ENSG00000137996"	"RTCA"	"hsa:8634; O00442; Q5VVL5; Q5VVL6; Q96E99"	""	""	"0"	"0"	"50.3"	"35.4"	"152.1"	"49.4"	"52.4"	"34.8"	"192.5"	"18.9"	"45.8"	"37.4"	"50.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z4V5"	"Hepatoma-derived growth factor-related protein 2 OS=Homo sapiens OX=9606 GN=HDGFL2 PE=1 SV=1"	"4"	"2"	"2"	"2"	"671"	"74.3"	"7.49"	""	"3.04"	""	"2"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00855, Pf11467"	"84717"	"ENSG00000167674"	"HDGFL2"	"hsa:84717; I3L080; K7EQZ6; Q7Z4V5; Q96GI5; Q9BW08"	""	""	"0"	"0"	"139.9"	"166.3"	"554.4"	"98.1"	"133.9"	"119.7"	"522.3"	"78.1"	"115.9"	"80.1"	"78.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94966"	"Ubiquitin carboxyl-terminal hydrolase 19 OS=Homo sapiens OX=9606 GN=USP19 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1318"	"145.6"	"6.28"	"390.43"	"3.03"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;ER/Golgi"	"other molecular function"	"Pf00443, Pf01753, Pf04969, Pf16602"	"10869"	"ENSG00000172046"	"USP19"	"A5PKX8; A6H8U2; B4DGT3; B4DTZ0; E7EN22; E7ETS0; E9PEG8; hsa:10869; O94966; Q3KQW4; Q641Q9; Q6NZY8; Q86XV9"	"Ub-specific processing proteases"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q8N954"	"G patch domain-containing protein 11 OS=Homo sapiens OX=9606 GN=GPATCH11 PE=1 SV=4"	"5"	"1"	"2"	"1"	"285"	"33.3"	"5.86"	"310.57"	"3.03"	"1"	"1"	""	"other cell component"	"nucleic acid binding activity"	"Pf01585, Pf13821"	"253635"	""	"GPATCH11"	"A0A0A0MSF9; A8K0D9; B7Z2G4; B8ZZ44; hsa:253635; Q8N954"	""	""	"0"	"0"	"16.4"	"18.3"	"61.7"	"19.9"	"18.1"	"15.7"	"68.5"	"9.1"	"15.5"	"11.8"	"21.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P43246"	"DNA mismatch repair protein Msh2 OS=Homo sapiens OX=9606 GN=MSH2 PE=1 SV=1"	"1"	"1"	"2"	"1"	"934"	"104.7"	"5.77"	"347.98"	"3.03"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00488, Pf01624, Pf05188, Pf05190, Pf05192"	"4436"	"ENSG00000095002"	"MSH2"	"B4E2Z2; hsa:4436; O75488; P43246"	"TP53 Regulates Transcription of DNA Repair Genes; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta); Defective Mismatch Repair Associated With MSH3; Defective Mismatch Repair Associated With MSH2; Defective Mismatch Repair Associated With MSH6"	"RAC1/PAK1/p38/MMP2 pathway; Chromosomal and microsatellite instability in colorectal cancer ; Ciliary landscape; DNA repair pathways, full network; p53 transcriptional gene network; DNA mismatch repair"	"12"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9H977"	"WD repeat-containing protein 54 OS=Homo sapiens OX=9606 GN=WDR54 PE=1 SV=1"	"4"	"1"	"1"	"1"	"334"	"35.9"	"6.20"	""	"3.03"	""	"1"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"other molecular function"	""	"84058"	"ENSG00000005448"	"WDR54"	"B9A049; D6W5I3; hsa:84058; Q53H85; Q86V45; Q9H977"	""	""	"0"	"0"	"218.0"	"148.8"	"1387.0"	"354.3"	"266.6"	"229.6"	"845.0"	"16.3"	"65.3"	"39.4"	"23.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IVD9"	"NudC domain-containing protein 3 OS=Homo sapiens OX=9606 GN=NUDCD3 PE=1 SV=3"	"4"	"1"	"3"	"1"	"361"	"40.8"	"5.25"	"556.48"	"3.03"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"other molecular function"	"Pf04969, Pf14050"	"23386"	"ENSG00000015676"	"NUDCD3"	"hsa:23386; Q8IVD9; Q9BTI3; Q9H7W9; Q9UPT4"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HCK8"	"Chromodomain-helicase-DNA-binding protein 8 OS=Homo sapiens OX=9606 GN=CHD8 PE=1 SV=5"	"1"	"1"	"2"	"1"	"2581"	"290.3"	"6.47"	"251.48"	"3.02"	"1"	"1"	"cell-cell signaling;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf00385, Pf07533"	"57680"	"ENSG00000100888"	"CHD8"	"hsa:57680; Q4G0D8; Q68DQ0; Q6DKH9; Q6P440; Q6ZNL7; Q8N3Z9; Q8NCY4; Q8TBR9; Q96F26; Q9HCK8"	"Deactivation of the beta-catenin transactivating complex"	"lncRNA in canonical Wnt signaling and colorectal cancer; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Pleural mesothelioma"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P15104"	"Glutamine synthetase OS=Homo sapiens OX=9606 GN=GLUL PE=1 SV=4"	"6"	"1"	"1"	"1"	"373"	"42.0"	"6.89"	""	"3.02"	""	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;other cell component"	"other molecular function"	"Pf00120, Pf03951"	"2752"	"ENSG00000135821"	"GLUL"	"hsa:2752; P15104; Q499Y9; Q5T9Z1; Q7Z3W4; Q8IZ17"	"Glutamate and glutamine metabolism; Astrocytic Glutamate-Glutamine Uptake And Metabolism"	"TNF-alpha signaling pathway; Amino acid metabolism"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9BZ29"	"Dedicator of cytokinesis protein 9 OS=Homo sapiens OX=9606 GN=DOCK9 PE=1 SV=2"	"1"	"1"	"2"	"1"	"2069"	"236.3"	"7.49"	"356.39"	"3.02"	"1"	"1"	"signal transduction;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity"	"Pf00169, Pf06920, Pf11878, Pf14429, Pf20421, Pf20422"	"23348"	"ENSG00000088387"	"DOCK9"	"B3KX25; E9PFM9; hsa:23348; Q5JUD4; Q5JUD6; Q5T2Q1; Q5TAN8; Q9BZ25; Q9BZ26; Q9BZ27; Q9BZ28; Q9BZ29; Q9UPU4"	"CDC42 GTPase cycle; RAC1 GTPase cycle; Factors involved in megakaryocyte development and platelet production"	""	"3"	"0"	"11.2"	"14.8"	"43.9"	"16.0"	"13.7"	"15.8"	"49.8"	"16.8"	"47.7"	"52.6"	"42.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14019"	"Coactosin-like protein OS=Homo sapiens OX=9606 GN=COTL1 PE=1 SV=3"	"6"	"1"	"2"	"1"	"142"	"15.9"	"5.67"	"333.64"	"3.02"	"1"	"1"	"cell organization and biogenesis;stress response"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00241"	"23406"	"ENSG00000103187"	"COTL1"	"B2RDU3; D3DUL9; hsa:23406; Q14019; Q86XM5"	"Neutrophil degranulation"	""	"1"	"0"	"143.2"	"147.6"	"639.6"	"145.3"	"122.7"	"82.4"	"729.6"	"88.2"	"109.8"	"89.9"	"76.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NRR5"	"Ubiquilin-4 OS=Homo sapiens OX=9606 GN=UBQLN4 PE=1 SV=2"	"2"	"1"	"2"	"1"	"601"	"63.8"	"5.22"	"405.20"	"3.02"	"1"	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00240, Pf00627"	"56893"	"ENSG00000160803"	"UBQLN4"	"A6ND44; B2RAY7; hsa:56893; Q5VYA0; Q5VYA1; Q9BR98; Q9NRR5; Q9UHX4"	""	""	"0"	"0"	"9.6"	"9.1"	"111.7"	"13.8"	"9.9"	"5.1"	"158.3"	"5.0"	"3.9"	"3.7"	"5.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NYK5"	"39S ribosomal protein L39, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL39 PE=1 SV=3"	"3"	"1"	"2"	"1"	"338"	"38.7"	"7.65"	"311.51"	"3.01"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	""	"54148"	"ENSG00000154719"	"MRPL39"	"C9JYA5; hsa:54148; Q32Q74; Q5QTR3; Q96Q65; Q9BSQ7; Q9BZV6; Q9NX44; Q9NYK5"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"17.2"	"21.5"	"66.9"	"11.7"	"16.8"	"15.1"	"76.9"	"5.0"	"3.9"	"5.6"	"7.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BUI4"	"DNA-directed RNA polymerase III subunit RPC3 OS=Homo sapiens OX=9606 GN=POLR3C PE=1 SV=1"	"4"	"1"	"2"	"1"	"534"	"60.6"	"7.31"	"473.70"	"3.01"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf05645, Pf08221"	"10623"	"ENSG00000186141"	"POLR3C"	"hsa:10623; O15317; Q9BUI4; Q9Y3R6"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation"	"Pyrimidine metabolism; Cytosolic DNA-sensing pathway"	"9"	"0"	"17.4"	"14.7"	"52.4"	"17.0"	"15.2"	"10.8"	"47.8"	"7.7"	"9.2"	"6.3"	"7.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30622"	"CAP-Gly domain-containing linker protein 1 OS=Homo sapiens OX=9606 GN=CLIP1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1438"	"162.1"	"5.36"	"264.14"	"3.01"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01302, Pf16641"	"6249"	"ENSG00000130779"	"CLIP1"	"A0AVD3; hsa:6249; P30622; Q17RS4; Q29RG0"	"Resolution of Sister Chromatid Cohesion; Separation of Sister Chromatids; RHO GTPases activate IQGAPs; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"Microtubule cytoskeleton regulation"	"8"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92878"	"DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1312"	"153.8"	"6.89"	"398.80"	"3.01"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04423, Pf13476, Pf13558"	"10111"	"ENSG00000113522"	"RAD50"	"B9EGF5; hsa:10111; O43254; Q6GMT7; Q6P5X3; Q92878; Q9UP86"	"Sensing of DNA Double Strand Breaks; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Resolution of D-loop Structures through Holliday Junction Intermediates; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; Meiotic recombination; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; DNA Damage/Telomere Stress Induced Senescence; Nonhomologous End-Joining (NHEJ); HDR through MMEJ (alt-NHEJ)"	"miRNA regulation of DNA damage response; Homologous recombination; DDX1 as a regulatory component of the Drosha microprocessor; ATM signaling in development and disease ; Breast cancer pathway; Joubert syndrome; DNA repair pathways, full network; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; DNA damage response"	"29"	"0"	"58.1"	"48.3"	"194.8"	"38.3"	"17.7"	"25.4"	"111.7"	"10.9"	"19.7"	"12.3"	"15.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13131"	"5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens OX=9606 GN=PRKAA1 PE=1 SV=4"	"3"	"1"	"2"	"1"	"559"	"64.0"	"8.12"	"310.84"	"3.01"	"1"	"1"	"cell-cell signaling;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;kinase activity;other molecular function"	"Pf00069, Pf16579"	"5562"	"ENSG00000132356"	"PRKAA1"	"A8MTQ6; B2R7E1; hsa:5562; O00286; Q13131; Q5D0E1; Q86VS1; Q9UNQ4"	"Activation of AMPK downstream of NMDARs; Regulation of TP53 Activity through Phosphorylation; TP53 Regulates Metabolic Genes; Macroautophagy; Energy dependent regulation of mTOR by LKB1-AMPK"	"AMP-activated protein kinase signaling; Target of rapamycin signaling; Energy metabolism; Thyroxine (thyroid hormone) production; Sterol regulatory element-binding proteins (SREBP) signaling; SREBF and miR33 in cholesterol and lipid homeostasis; Leptin signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; mir-124 predicted interactions with cell cycle and differentiation ; ATM signaling in development and disease ; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Leptin and adiponectin; Lipid metabolism pathway; PI3K-Akt signaling pathway; Thermogenesis; Nonalcoholic fatty liver disease; Synaptic signaling pathways associated with autism spectrum disorder; Hippo signaling regulation pathways; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Head and neck squamous cell carcinoma; IL-18 signaling pathway; Insulin signaling; 1q21.1 copy number variation syndrome; Autophagy; p53 transcriptional gene network; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Pleural mesothelioma; Disturbed pathways in Duchenne Muscular Dystrophy"	"35"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q14331"	"Protein FRG1 OS=Homo sapiens OX=9606 GN=FRG1 PE=1 SV=1"	"5"	"1"	"2"	"1"	"258"	"29.2"	"9.01"	"473.08"	"3.00"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus"	"cytoskeletal activity"	"Pf06229"	"2483"	"ENSG00000109536; ENSG00000275145; ENSG00000283153; ENSG00000283630"	"FRG1"	"A8K775; hsa:2483; Q14331"	""	""	"0"	"0"	"63.5"	"58.9"	"195.8"	"57.7"	"59.4"	"42.9"	"242.1"	"48.8"	"146.0"	"233.9"	"320.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TCF1"	"AN1-type zinc finger protein 1 OS=Homo sapiens OX=9606 GN=ZFAND1 PE=1 SV=1"	"5"	"1"	"2"	"1"	"268"	"30.8"	"7.39"	"327.67"	"3.00"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"other cell component"	"other molecular function"	"Pf01428"	"79752"	"ENSG00000104231"	"ZFAND1"	"E5RIG0; E5RJ99; hsa:79752; Q658R7; Q6IA32; Q6PGQ6; Q8TCF1; Q9H810"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3E7"	"Charged multivesicular body protein 3 OS=Homo sapiens OX=9606 GN=CHMP3 PE=1 SV=3"	"5"	"1"	"2"	"1"	"222"	"25.1"	"5.12"	"364.21"	"3.00"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf03357"	"100526767; 51652"	"ENSG00000115561"	"CHMP3"	"A8K3W0; B4DG34; B8ZZM0; B8ZZX5; hsa:100526767; hsa:51652; Q3ZTS9; Q53S71; Q53SU5; Q9NZ51; Q9Y3E7"	"HCMV Late Events; Budding and maturation of HIV virion; Endosomal Sorting Complex Required For Transport (ESCRT); Late endosomal microautophagy; Sealing of the nuclear envelope (NE) by ESCRT-III; Macroautophagy; Pyroptosis; Translation of Replicase and Assembly of the Replication Transcription Complex; Translation of Replicase and Assembly of the Replication Transcription Complex"	""	"9"	"0"	"7.3"	"9.5"	"42.6"	"8.9"	"7.9"	"4.4"	"47.7"	"3.7"	"4.7"	"9.6"	"3.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BV20"	"Methylthioribose-1-phosphate isomerase OS=Homo sapiens OX=9606 GN=MRI1 PE=1 SV=1"	"6"	"2"	"3"	"2"	"369"	"39.1"	"6.30"	"497.58"	"2.99"	"2"	"1"	"other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01008"	"84245"	"ENSG00000037757"	"MRI1"	"hsa:84245; Q8NDC9; Q9BV20"	"Methionine salvage pathway"	"Methionine de novo and salvage pathway"	"2"	"0"	"165.8"	"172.4"	"466.4"	"172.3"	"128.1"	"122.0"	"506.0"	"86.0"	"126.8"	"115.0"	"109.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4X0"	"AMME syndrome candidate gene 1 protein OS=Homo sapiens OX=9606 GN=AMMECR1 PE=1 SV=1"	"4"	"1"	"2"	"1"	"333"	"35.4"	"8.63"	"317.92"	"2.99"	"1"	"1"	""	"mitochondrion;nucleus"	""	"Pf01871"	"9949"	"ENSG00000101935"	"AMMECR1"	"hsa:9949; Q5JYV9; Q6P9D8; Q8WX22; Q9UIQ8; Q9Y4X0"	""	""	"0"	"0"	"13.1"	"17.2"	"33.4"	"12.4"	"13.5"	"8.2"	"54.7"	"17.3"	"30.4"	"23.3"	"27.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30046"	"D-dopachrome decarboxylase OS=Homo sapiens OX=9606 GN=DDT PE=1 SV=3"	"9"	"1"	"2"	"1"	"118"	"12.7"	"7.30"	"250.30"	"2.99"	"1"	"1"	"other metabolic processes;other biological processes"	"non-structural extracellular;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01187"	"1652"	"ENSG00000099977; ENSG00000275003"	"DDT"	"B7Z522; hsa:1652; O00774; O60787; P30046; Q13534"	""	""	"0"	"0"	"5.6"	"8.0"	"65.7"	"7.0"	"2.7"	"3.0"	"76.3"	"2.7"	"2.2"	"2.6"	"0.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"P18858"	"DNA ligase 1 OS=Homo sapiens OX=9606 GN=LIG1 PE=1 SV=1"	"3"	"2"	"3"	"2"	"919"	"101.7"	"5.62"	"817.53"	"2.99"	"2"	"1"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01068, Pf04675, Pf04679"	"3978"	"ENSG00000105486"	"LIG1"	"B2RAI8; B4DTU4; hsa:3978; P18858; Q2TB12; Q32P23"	"Gap-filling DNA repair synthesis and ligation in TC-NER; Early Phase of HIV Life Cycle; POLB-Dependent Long Patch Base Excision Repair; PCNA-Dependent Long Patch Base Excision Repair; Processive synthesis on the lagging strand; Gap-filling DNA repair synthesis and ligation in GG-NER; Processive synthesis on the C-strand of the telomere; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"Base excision repair; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"14"	"0"	"23.6"	"21.1"	"84.0"	"20.3"	"25.4"	"14.1"	"144.9"	"15.4"	"23.2"	"17.4"	"16.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P53365"	"Arfaptin-2 OS=Homo sapiens OX=9606 GN=ARFIP2 PE=1 SV=1"	"5"	"1"	"2"	"1"	"341"	"37.8"	"6.04"	"264.55"	"2.98"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf06456"	"23647"	"ENSG00000132254"	"ARFIP2"	"B4DX86; B4E306; D3DQT5; hsa:23647; P53365"	"Retrograde transport at the Trans-Golgi-Network"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9NQR4"	"Omega-amidase NIT2 OS=Homo sapiens OX=9606 GN=NIT2 PE=1 SV=1"	"4"	"1"	"2"	"1"	"276"	"30.6"	"7.21"	"364.14"	"2.98"	"1"	"1"	"other metabolic processes"	"non-structural extracellular;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00795"	"56954"	"ENSG00000114021"	"NIT2"	"B2R9A3; D3DN47; hsa:56954; Q8WUF0; Q9NQR4"	"Neutrophil degranulation"	""	"1"	"0"	"11.3"	"11.4"	"73.8"	"11.4"	"11.4"	"6.0"	"113.7"	"5.7"	"5.1"	"6.2"	"10.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43765"	"Small glutamine-rich tetratricopeptide repeat-containing protein alpha OS=Homo sapiens OX=9606 GN=SGTA PE=1 SV=1"	"4"	"1"	"2"	"1"	"313"	"34.0"	"4.87"	"291.20"	"2.97"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00515, Pf13181, Pf16546"	"6449"	"ENSG00000104969"	"SGTA"	"D6W610; hsa:6449; O43765; Q6FIA9; Q9BTZ9"	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"	""	"1"	"0"	"33.1"	"33.2"	"228.6"	"33.5"	"28.2"	"18.4"	"294.0"	"21.9"	"33.9"	"12.7"	"13.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQG0"	"Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2"	"2"	"2"	"2"	"2"	"1328"	"148.8"	"9.28"	"417.87"	"2.97"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04931"	"10514"	"ENSG00000132382"	"MYBBP1A"	"hsa:10514; Q86VM3; Q9BQG0; Q9BW49; Q9P0V5; Q9UF99"	"B-WICH complex positively regulates rRNA expression"	"Energy metabolism"	"2"	"0"	"10.6"	"17.6"	"70.1"	"12.9"	"13.5"	"11.0"	"47.6"	"2.4"	"1.8"	"0.0"	"4.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H446"	"RWD domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RWDD1 PE=1 SV=1"	"7"	"1"	"2"	"1"	"243"	"27.9"	"4.20"	"241.88"	"2.97"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"other cell component"	""	"Pf05773"	"51389"	"ENSG00000111832"	"RWDD1"	"A8K3W2; A8MT24; hsa:51389; Q9H446; Q9Y313; Q9Y6B3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14554"	"Protein disulfide-isomerase A5 OS=Homo sapiens OX=9606 GN=PDIA5 PE=1 SV=1"	"2"	"1"	"1"	"1"	"519"	"59.6"	"7.91"	""	"2.97"	""	"1"	"other metabolic processes;other biological processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf00085"	"10954"	"ENSG00000065485"	"PDIA5"	"D3DN95; hsa:10954; Q14554; Q9BV43"	"XBP1(S) activates chaperone genes"	""	"1"	"0"	"14.9"	"21.1"	"51.8"	"13.4"	"17.9"	"17.6"	"32.0"	"9.9"	"23.4"	"28.5"	"37.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q969V3"	"Nicalin OS=Homo sapiens OX=9606 GN=NCLN PE=1 SV=2"	"2"	"1"	"2"	"1"	"563"	"62.9"	"6.89"	"245.92"	"2.97"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"other membranes;cytosol;ER/Golgi;other cell component"	"translation activity"	"Pf04389"	"56926"	"ENSG00000125912"	"NCLN"	"D6W613; hsa:56926; O75252; Q6FI60; Q6ZMB7; Q8TAT7; Q969V3; Q96H48; Q96IS7; Q9BQH9; Q9BTX4; Q9NPP2"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NUQ8"	"ATP-binding cassette sub-family F member 3 OS=Homo sapiens OX=9606 GN=ABCF3 PE=1 SV=2"	"2"	"1"	"2"	"1"	"709"	"79.7"	"6.34"	"433.60"	"2.97"	"1"	"1"	"stress response"	""	"other molecular function"	"Pf00005, Pf12848"	"55324"	"ENSG00000161204"	"ABCF3"	"A8K241; hsa:55324; Q86UA2; Q8NAN1; Q96GS8; Q9H7A8; Q9NUQ8"	""	""	"0"	"0"	"13.2"	"18.3"	"56.2"	"10.9"	"11.4"	"6.6"	"63.6"	"5.5"	"7.4"	"7.3"	"4.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P20936"	"Ras GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RASA1 PE=1 SV=1"	"1"	"1"	"1"	"1"	"1047"	"116.3"	"6.54"	""	"2.97"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00017, Pf00018, Pf00168, Pf00169, Pf00616"	"5921"	"ENSG00000145715"	"RASA1"	"B2R6W3; B4DTL2; hsa:5921; P20936; Q68CU6; Q9UDI1"	"Regulation of RAS by GAPs; EPHB-mediated forward signaling; Downstream signal transduction; VEGFR2 mediated cell proliferation; PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"	"Androgen receptor network in prostate cancer; PDGF pathway; T cell receptor and co-stimulatory signaling; Hepatocyte growth factor receptor signaling; RAC1/PAK1/p38/MMP2 pathway; MAPK signaling pathway; Ras signaling; Acute viral myocarditis; EGF/EGFR signaling pathway; GDNF signaling; EPO receptor signaling"	"16"	"0"	"10.8"	"12.4"	"40.7"	"11.9"	"13.9"	"12.2"	"45.3"	"6.5"	"11.7"	"9.7"	"9.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WUH6"	"Transmembrane protein 263 OS=Homo sapiens OX=9606 GN=TMEM263 PE=1 SV=1"	"10"	"1"	"2"	"1"	"116"	"11.7"	"9.32"	"287.82"	"2.97"	"1"	"1"	""	"other membranes"	""	"Pf15475"	"90488"	"ENSG00000151135"	"TMEM263"	"B3KMN9; hsa:90488; Q8WUH6"	""	""	"0"	"0"	"22.1"	"24.6"	"47.1"	"18.2"	"23.1"	"14.2"	"81.9"	"22.5"	"29.9"	"22.6"	"17.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y696"	"Chloride intracellular channel protein 4 OS=Homo sapiens OX=9606 GN=CLIC4 PE=1 SV=4"	"18"	"3"	"3"	"2"	"253"	"28.8"	"5.59"	"499.82"	"2.96"	"2"	"1"	"transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"transporter activity"	"Pf13410"	"25932"	"ENSG00000169504"	"CLIC4"	"hsa:25932; Q9UFW9; Q9UQJ6; Q9Y696"	""	""	"0"	"0"	"8.8"	"8.9"	"40.0"	"8.3"	"7.4"	"5.7"	"46.5"	"4.4"	"7.4"	"7.5"	"6.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46934"	"E3 ubiquitin-protein ligase NEDD4 OS=Homo sapiens OX=9606 GN=NEDD4 PE=1 SV=4"	"1"	"1"	"2"	"1"	"1319"	"149.0"	"6.58"	"343.62"	"2.96"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00397, Pf00632"	"4734"	"ENSG00000069869"	"NEDD4"	"A1KY35; A6ND72; A7MD29; B4E2R7; B7ZM59; B7ZM60; B9EGN5; D6RF89; hsa:4734; P46934"	"ISG15 antiviral mechanism; Antigen processing: Ubiquitination & Proteasome degradation; Regulation of PTEN stability and activity; Downregulation of ERBB4 signaling; Regulation of PTEN localization"	"Proteasome degradation; Ebola virus infection in host; EGF/EGFR signaling pathway; LDLRAD4 and what we know about it"	"9"	"0"	"17.7"	"20.2"	"51.4"	"19.5"	"16.8"	"15.0"	"55.3"	"13.1"	"11.4"	"13.1"	"12.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43847"	"Nardilysin OS=Homo sapiens OX=9606 GN=NRDC PE=1 SV=3"	"1"	"1"	"2"	"1"	"1151"	"131.6"	"4.98"	"334.38"	"2.95"	"1"	"1"	"protein metabolism;other biological processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00675, Pf05193, Pf16187"	"4898"	"ENSG00000078618"	"NRDC"	"A6NI41; hsa:4898; O15241; O15242; O43847; Q5VUL0; Q96HB2; Q9NU57"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NQC8"	"Intraflagellar transport protein 46 homolog OS=Homo sapiens OX=9606 GN=IFT46 PE=1 SV=1"	"7"	"1"	"2"	"1"	"304"	"34.3"	"4.54"	"318.96"	"2.95"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"cytoskeleton;other cell component"	""	"Pf12317"	"56912"	"ENSG00000118096"	"IFT46"	"A8K0F6; hsa:56912; Q9H6V5; Q9NQC8"	"Intraflagellar transport"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein; Genes related to primary cilium development (based on CRISPR)"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q5T160"	"Probable arginine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=RARS2 PE=1 SV=1"	"3"	"1"	"2"	"1"	"578"	"65.5"	"8.21"	"449.23"	"2.94"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00750, Pf05746"	"57038"	"ENSG00000146282"	"RARS2"	"B2RDT7; hsa:57038; Q5T160; Q96FU5; Q9H8K8"	"Mitochondrial tRNA aminoacylation"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"P41223"	"Protein BUD31 homolog OS=Homo sapiens OX=9606 GN=BUD31 PE=1 SV=2"	"7"	"1"	"1"	"1"	"144"	"17.0"	"8.82"	""	"2.94"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf01125"	"8896"	"ENSG00000106245"	"BUD31"	"A4D274; B7Z4S9; D6W5S6; hsa:8896; P41223; Q6IB53; Q9UDV1"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6NYC1"	"Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 OS=Homo sapiens OX=9606 GN=JMJD6 PE=1 SV=1"	"3"	"1"	"2"	"1"	"403"	"46.4"	"8.69"	"287.31"	"2.93"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02373"	"23210"	"ENSG00000070495"	"JMJD6"	"B3KMN8; B4DGX1; hsa:23210; Q6NYC1; Q86VY0; Q8IUM5; Q9Y4E2"	"HDMs demethylate histones"	""	"1"	"0"	"14.9"	"19.9"	"73.3"	"21.4"	"19.7"	"23.5"	"70.7"	"18.2"	"12.5"	"6.0"	"9.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46199"	"Translation initiation factor IF-2, mitochondrial OS=Homo sapiens OX=9606 GN=MTIF2 PE=1 SV=2"	"2"	"1"	"2"	"1"	"727"	"81.3"	"7.15"	"351.85"	"2.93"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00009, Pf11987"	"4528"	"ENSG00000085760"	"MTIF2"	"D6W5D0; hsa:4528; P46199"	"Mitochondrial translation initiation"	""	"1"	"0"	"17.3"	"18.0"	"65.8"	"15.1"	"14.5"	"12.5"	"60.8"	"9.5"	"16.9"	"14.6"	"22.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43169"	"Cytochrome b5 type B OS=Homo sapiens OX=9606 GN=CYB5B PE=1 SV=3"	"10"	"2"	"3"	"2"	"150"	"16.7"	"4.97"	"516.38"	"2.93"	"2"	"1"	"other metabolic processes;stress response"	"other membranes;mitochondrion;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00173"	"80777"	"ENSG00000103018"	"CYB5B"	"A8K6B1; hsa:80777; J3KNF8; O43169; Q96CC3; Q9BT35"	"Phase I - Functionalization of compounds"	"Oxidation by cytochrome P450"	"2"	"0"	"28.8"	"31.1"	"140.2"	"39.8"	"39.5"	"54.8"	"157.7"	"25.0"	"19.2"	"47.9"	"18.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UPT8"	"Zinc finger CCCH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=ZC3H4 PE=1 SV=3"	"1"	"1"	"2"	"1"	"1303"	"140.2"	"6.27"	"326.21"	"2.93"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00642, Pf14608, Pf18044"	"23211"	"ENSG00000130749"	"ZC3H4"	"hsa:23211; Q9UPT8; Q9Y420"	""	""	"0"	"0"	"32.5"	"25.8"	"77.8"	"25.9"	"26.6"	"22.6"	"77.9"	"12.5"	"19.9"	"17.8"	"11.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P47756"	"F-actin-capping protein subunit beta OS=Homo sapiens OX=9606 GN=CAPZB PE=1 SV=4"	"3"	"1"	"2"	"1"	"277"	"31.3"	"5.59"	"268.76"	"2.93"	"1"	"1"	"cell organization and biogenesis"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf01115"	"100612860; 101140941"	"ENSGGOG00000003982; ENSPPYG00000001789; ENSPTRG00000000268"	"CAPZB"	"A0A2J8KEQ9; A0A2J8T2J3; A0A6D2W7V0; A0A6D2XKL1; A0A8B6ZIG4; A0A9B0TL78; G3QN07; H2N8T0; H2R9E0"	""	""	"0"	"0"	"88.9"	"95.0"	"331.2"	"102.5"	"111.8"	"83.6"	"505.6"	"85.4"	"166.6"	"126.2"	"121.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96JP5"	"E3 ubiquitin-protein ligase ZFP91 OS=Homo sapiens OX=9606 GN=ZFP91 PE=1 SV=1"	"2"	"1"	"2"	"1"	"570"	"63.4"	"7.36"	"387.33"	"2.93"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"nucleus"	"other molecular function"	"Pf00096"	"80829"	"ENSG00000186660"	"ZFP91"	"A6NHC4; A8MSG7; hsa:80829; Q86V47; Q96JP4; Q96JP5; Q96QA3"	""	""	"0"	"0"	"8.4"	"12.6"	"29.5"	"7.5"	"7.0"	"5.8"	"44.4"	"6.7"	"9.3"	"6.8"	"9.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4C1"	"Lysine-specific demethylase 3A OS=Homo sapiens OX=9606 GN=KDM3A PE=1 SV=4"	"1"	"1"	"2"	"1"	"1321"	"147.2"	"8.07"	"278.21"	"2.93"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02373"	"55818"	"ENSG00000115548"	"KDM3A"	"D6W5M3; hsa:55818; Q53S72; Q68D47; Q68UT9; Q6N050; Q8IY08; Q9Y4C1"	"HDMs demethylate histones; NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"	"Thermogenesis; Male infertility; Vitamin D-sensitive calcium signaling in depression"	"5"	"0"	"15.2"	"14.3"	"40.3"	"9.8"	"17.0"	"13.0"	"35.5"	"11.4"	"11.1"	"13.9"	"8.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q03001"	"Dystonin OS=Homo sapiens OX=9606 GN=DST PE=1 SV=4"	"0"	"1"	"2"	"1"	"7570"	"860.1"	"5.25"	"329.37"	"2.93"	"1"	"1"	"cell adhesion;cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"extracellular matrix;plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00307, Pf00435, Pf00681, Pf02187, Pf13499, Pf17902, Pf18373"	"667"	"ENSG00000151914"	"DST"	"B7Z3H1; E7ERU0; hsa:667; O94833; Q03001; Q12825; Q13266; Q13267; Q13775; Q5TBT0; Q5TBT2; Q5TF23; Q5TF24; Q8N1T8; Q8N8J3; Q8WXK8; Q8WXK9; Q96AK9; Q96DQ5; Q96J76; Q96QT5; Q9H555; Q9UGD7; Q9UGD8; Q9UN10"	"RND1 GTPase cycle; RND2 GTPase cycle; RHOV GTPase cycle; RHOU GTPase cycle; RND3 GTPase cycle; Type I hemidesmosome assembly"	""	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q8TBC4"	"NEDD8-activating enzyme E1 catalytic subunit OS=Homo sapiens OX=9606 GN=UBA3 PE=1 SV=2"	"2"	"1"	"2"	"1"	"463"	"51.8"	"5.45"	"252.92"	"2.92"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00899, Pf08825"	"9039"	"ENSG00000144744"	"UBA3"	"A6NLB5; A8K027; hsa:9039; O76088; Q8TBC4; Q9NTU3"	"Antigen processing: Ubiquitination & Proteasome degradation; Dectin-1 mediated noncanonical NF-kB signaling; NIK-->noncanonical NF-kB signaling; Neddylation"	"Hijack of ubiquitination by SARS-CoV-2"	"5"	"0"	"6.6"	"10.9"	"51.1"	"10.1"	"9.5"	"6.3"	"58.5"	"5.8"	"7.3"	"0.0"	"3.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NZ52"	"ADP-ribosylation factor-binding protein GGA3 OS=Homo sapiens OX=9606 GN=GGA3 PE=1 SV=1"	"2"	"1"	"2"	"1"	"723"	"78.3"	"5.58"	"246.03"	"2.92"	"1"	"1"	"protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00790, Pf02883, Pf03127, Pf18308"	"23163"	"ENSG00000125447"	"GGA3"	"B7Z7E2; B7Z7M9; hsa:23163; J3KRN0; Q15017; Q6IS16; Q9NZ52; Q9UJY3"	"Amyloid fiber formation; TBC/RABGAPs; MET receptor recycling"	""	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"O15234"	"Protein CASC3 OS=Homo sapiens OX=9606 GN=CASC3 PE=1 SV=2"	"2"	"1"	"2"	"1"	"703"	"76.2"	"6.48"	"305.76"	"2.92"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09405"	"22794"	"ENSG00000108349"	"CASC3"	"A8K8R0; hsa:22794; O15234"	"Regulation of expression of SLITs and ROBOs; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	""	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q04727"	"Transducin-like enhancer protein 4 OS=Homo sapiens OX=9606 GN=TLE4 PE=1 SV=3"	"1"	"1"	"2"	"1"	"773"	"83.7"	"7.50"	"369.33"	"2.92"	"1"	"1"	"cell-cell signaling;RNA metabolism OR transcription;signal transduction;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00400, Pf03920"	"7091"	"ENSG00000106829"	"TLE4"	"F8W6T6; hsa:7091; Q04727; Q3ZCS1; Q5T1Y2; Q6PCB3; Q9BZ07; Q9BZ08; Q9BZ09; Q9NSL3; Q9ULF9"	"Formation of the beta-catenin:TCF transactivating complex; Deactivation of the beta-catenin transactivating complex; NOTCH1 Intracellular Domain Regulates Transcription; Repression of WNT target genes"	""	"4"	"0"	"53.1"	"60.8"	"176.6"	"51.2"	"53.5"	"36.6"	"215.0"	"33.2"	"54.3"	"42.2"	"45.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75312"	"Zinc finger protein ZPR1 OS=Homo sapiens OX=9606 GN=ZPR1 PE=1 SV=1"	"3"	"1"	"2"	"1"	"459"	"50.9"	"4.73"	"314.56"	"2.91"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf03367"	"8882"	"ENSG00000109917"	"ZPR1"	"hsa:8882; O75312; Q2TAA0"	""	""	"0"	"0"	"20.3"	"14.6"	"63.3"	"22.2"	"19.2"	"12.6"	"77.4"	"11.1"	"12.4"	"10.5"	"8.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49023"	"Paxillin OS=Homo sapiens OX=9606 GN=PXN PE=1 SV=3"	"2"	"1"	"2"	"1"	"591"	"64.5"	"6.19"	"401.05"	"2.91"	"1"	"1"	"cell adhesion;cell organization and biogenesis;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00412, Pf03535"	"5829"	"ENSG00000089159"	"PXN"	"B2RAI3; B7ZMB4; hsa:5829; O14970; O14971; O60360; P49023; Q5HYA4"	"VEGFA-VEGFR2 Pathway; GAB1 signalosome; Smooth Muscle Contraction; PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases; Localization of the PINCH-ILK-PARVIN complex to focal adhesions; Regulation of cytoskeletal remodeling and cell spreading by IPP complex components"	"Integrin-mediated cell adhesion; Prolactin signaling pathway; Androgen receptor network in prostate cancer; Oncostatin M signaling pathway; Focal adhesion; Hepatocyte growth factor receptor signaling; RAC1/PAK1/p38/MMP2 pathway; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Gastrin signaling pathway; 3q29 copy number variation syndrome; Regulation of actin cytoskeleton; GDNF signaling"	"20"	"0"	"33.5"	"39.6"	"151.6"	"62.2"	"62.7"	"59.1"	"150.6"	"35.0"	"44.0"	"36.6"	"38.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95299"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFA10 PE=1 SV=1"	"3"	"1"	"2"	"1"	"355"	"40.7"	"8.48"	"260.80"	"2.91"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion;other cell component"	"transporter activity"	"Pf01712"	"4705"	"ENSG00000130414"	"NDUFA10"	"hsa:4705; O95299; Q8WXC9"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; 2q37 copy number variation syndrome; Oxidative phosphorylation"	"6"	"0"	"17.0"	"25.1"	"71.0"	"17.7"	"22.6"	"15.2"	"70.8"	"7.3"	"19.6"	"10.8"	"15.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96BP3"	"Peptidylprolyl isomerase domain and WD repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=PPWD1 PE=1 SV=1"	"2"	"1"	"2"	"1"	"646"	"73.5"	"7.15"	"296.32"	"2.90"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00160, Pf00400"	"23398"	"ENSG00000113593"	"PPWD1"	"B4DWR9; hsa:23398; Q15002; Q7KZ89; Q96BP3"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"17.3"	"11.2"	"55.1"	"16.4"	"16.8"	"13.3"	"64.3"	"9.4"	"10.8"	"11.4"	"10.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35611"	"Alpha-adducin OS=Homo sapiens OX=9606 GN=ADD1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"737"	"80.9"	"5.83"	"264.05"	"2.90"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00596"	"118"	"ENSG00000087274"	"ADD1"	"A2A3N8; A2A3P0; B4DI79; D3DVR3; D3DVR4; D3DVR5; hsa:118; P35611; Q13734; Q14729; Q16156; Q86XM2; Q9UJB6"	"XBP1(S) activates chaperone genes; Caspase-mediated cleavage of cytoskeletal proteins; Miscellaneous transport and binding events"	""	"3"	"0"	"61.7"	"69.1"	"221.6"	"71.0"	"72.8"	"55.5"	"255.4"	"39.6"	"69.8"	"48.1"	"49.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00151"	"PDZ and LIM domain protein 1 OS=Homo sapiens OX=9606 GN=PDLIM1 PE=1 SV=4"	"6"	"2"	"3"	"2"	"329"	"36.0"	"7.02"	"652.28"	"2.90"	"2"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;stress response;developmental processes;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412, Pf00595, Pf15936"	"9124"	"ENSG00000107438"	"PDLIM1"	"B2RBS6; hsa:9124; O00151; Q5VZH5; Q9BPZ9"	""	""	"0"	"0"	"63.6"	"83.5"	"295.6"	"72.1"	"72.9"	"57.7"	"378.9"	"54.7"	"69.8"	"58.4"	"47.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95373"	"Importin-7 OS=Homo sapiens OX=9606 GN=IPO7 PE=1 SV=1"	"2"	"2"	"3"	"2"	"1038"	"119.4"	"4.82"	"629.27"	"2.89"	"2"	"1"	"stress response;transport;other biological processes"	"cytosol;nucleus"	"enzyme regulator activity;other molecular function"	"Pf03810, Pf08506"	"10527"	"ENSG00000205339"	"IPO7"	"A6NNM5; B2R786; hsa:10527; O95373; Q1RMF7; Q9H177; Q9NTE3"	""	""	"0"	"0"	"63.5"	"61.4"	"273.3"	"51.6"	"37.4"	"22.2"	"209.1"	"6.0"	"14.9"	"11.7"	"14.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75439"	"Mitochondrial-processing peptidase subunit beta OS=Homo sapiens OX=9606 GN=PMPCB PE=1 SV=2"	"2"	"1"	"2"	"1"	"489"	"54.3"	"6.83"	"234.21"	"2.89"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport"	"other membranes;mitochondrion"	"other molecular function"	"Pf00675, Pf05193"	"9512"	"ENSG00000105819"	"PMPCB"	"hsa:9512; O60416; O75439; Q96FV4"	"Mitochondrial protein import; Processing of SMDT1"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BVQ7"	"Spermatogenesis-associated protein 5-like protein 1 OS=Homo sapiens OX=9606 GN=SPATA5L1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"753"	"80.7"	"8.09"	"254.57"	"2.89"	"1"	"1"	"other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf17862"	"79029"	"ENSG00000171763"	"AFG2B"	"C9JHR5; hsa:79029; Q9BVQ7; Q9H8W7; Q9HA41"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"P18754"	"Regulator of chromosome condensation OS=Homo sapiens OX=9606 GN=RCC1 PE=1 SV=1"	"4"	"1"	"2"	"1"	"421"	"44.9"	"7.52"	"341.34"	"2.89"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00415"	"1104"	"ENSG00000180198"	"RCC1"	"hsa:1104; P18754; Q16269; Q6NT97"	"Rev-mediated nuclear export of HIV RNA; Nuclear import of Rev protein; Postmitotic nuclear pore complex (NPC) reformation"	"22q11.2 copy number variation syndrome"	"4"	"0"	"29.1"	"31.5"	"97.7"	"26.2"	"37.1"	"27.3"	"111.0"	"16.5"	"29.7"	"22.3"	"25.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HD47"	"Ran guanine nucleotide release factor OS=Homo sapiens OX=9606 GN=RANGRF PE=1 SV=1"	"7"	"1"	"2"	"1"	"186"	"20.4"	"4.94"	"367.18"	"2.89"	"1"	"1"	"transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf04603"	"29098"	"ENSG00000108961"	"RANGRF"	"D3DTR6; hsa:29098; Q68DI3; Q9BR68; Q9HD47; Q9HD48; Q9NRU9; Q9P001; Q9P0P2"	"Phase 0 - rapid depolarisation"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P45983"	"Mitogen-activated protein kinase 8 OS=Homo sapiens OX=9606 GN=MAPK8 PE=1 SV=2"	"3"	"1"	"2"	"1"	"427"	"48.3"	"6.89"	"353.15"	"2.89"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069"	"5599"	"ENSG00000107643"	"MAPK8"	"B5BTZ5; B7ZLV4; D3DX88; D3DX92; hsa:5599; P45983; Q15709; Q15712; Q15713; Q308M2"	"FCERI mediated MAPK activation; NRAGE signals death through JNK; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Oxidative Stress Induced Senescence; WNT5:FZD7-mediated leishmania damping; JNK (c-Jun kinases) phosphorylation and  activation mediated by activated human TAK1; DSCAM interactions; Activation of BIM and translocation to mitochondria ; Activation of the AP-1 family of transcription factors; NRIF signals cell death from the nucleus; Activation of BMF and translocation to mitochondria; Interleukin-38 signaling"	"Osteoclast signaling; Physiological and pathological hypertrophy of the heart; MicroRNAs in cardiomyocyte hypertrophy; Type II diabetes mellitus; IL-1 signaling pathway; RANKL/RANK signaling pathway; Leptin signaling pathway; TNF-related weak inducer of apoptosis (TWEAK) signaling pathway; Prolactin signaling pathway; Alzheimer's disease and miRNA effects; Thymic stromal lymphopoietin (TSLP) signaling pathway; Androgen receptor network in prostate cancer; B cell receptor signaling pathway; TNF-alpha signaling pathway; AGE/RAGE pathway; Corticotropin-releasing hormone signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Nanoparticle triggered regulated necrosis; Ebstein-Barr virus LMP1 signaling; Cardiac hypertrophic response; IL-3 signaling pathway; Nod-like receptor (NLR) signaling pathway; Transcriptional activation by NRF2 in response to phytochemicals; Kit receptor signaling pathway; Focal adhesion; Hepatocyte growth factor receptor signaling; Fas ligand pathway and stress induction of heat shock proteins; RAC1/PAK1/p38/MMP2 pathway; Transcription factor regulation in adipogenesis; Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling; Wnt signaling pathway; Hepatitis C and hepatocellular carcinoma; Hypothesized pathways in pathogenesis of cardiovascular disease; Physico-chemical features and toxicity-associated pathways; MAPK signaling pathway; Novel intracellular components of RIG-I-like receptor pathway; Canonical and non-canonical TGF-B signaling; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Wnt signaling in kidney disease; Chromosomal and microsatellite instability in colorectal cancer ; Ras signaling; Epithelial to mesenchymal transition in colorectal cancer; Pancreatic adenocarcinoma pathway; Ethanol metabolism production of ROS by CYP2E1; Wnt signaling; miRNA role in immune response in sepsis; Neovascularisation processes; Non-genomic actions of 1,25 dihydroxyvitamin D3; NRF2-ARE regulation; EGF/EGFR signaling pathway; Nonalcoholic fatty liver disease; Signal transduction through IL1R; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Regulatory circuits of the STAT3 signaling pathway; Translation inhibitors in chronically activated PDGFRA cells; Measles virus infection; Gastrin signaling pathway; Hepatitis B infection; Osteoblast differentiation and related diseases; Insulin signaling; Host-pathogen interaction of human coronaviruses - MAPK signaling; Host-pathogen interaction of human coronaviruses - interferon induction; Neuroinflammation; Pleural mesothelioma; CCL18 signaling pathway; Alzheimer's disease; Th17 cell differentiation pathway; GDNF signaling; Roles of ceramides in development of insulin resistance; IL-26 signaling pathways; A network map of Macrophage-stimulating protein (MSP) signaling; ErbB signaling pathway; T-cell receptor signaling pathway; DNA damage response (only ATM dependent); Toll-like receptor signaling pathway"	"89"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9C0B1"	"Alpha-ketoglutarate-dependent dioxygenase FTO OS=Homo sapiens OX=9606 GN=FTO PE=1 SV=3"	"4"	"1"	"2"	"1"	"505"	"58.2"	"5.22"	"383.87"	"2.89"	"1"	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf12933, Pf12934"	"79068"	"ENSG00000140718"	"FTO"	"A2RUH1; B2RNS0; hsa:79068; Q0P676; Q7Z785; Q9C0B1"	"Reversal of alkylation damage by DNA dioxygenases"	"FTO obesity variant mechanism"	"2"	"0"	"4.7"	"5.6"	"35.2"	"5.0"	"5.3"	"4.1"	"30.9"	"3.5"	"4.6"	"10.0"	"5.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NRZ9"	"Lymphoid-specific helicase OS=Homo sapiens OX=9606 GN=HELLS PE=1 SV=1"	"4"	"2"	"3"	"2"	"838"	"97.0"	"7.93"	"803.28"	"2.89"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00176, Pf00271"	"3070"	"ENSG00000119969"	"HELLS"	"B2RB41; hsa:3070; Q3LID1; Q6I7N7; Q76H76; Q76H77; Q76H78; Q76H79; Q76H80; Q76H81; Q7Z397; Q7Z5X2; Q8N6P4; Q9H4P5; Q9NRZ9"	""	"Apoptosis; Apoptosis-related network due to altered Notch3 in ovarian cancer"	"2"	"0"	"19.5"	"25.0"	"70.6"	"16.7"	"25.7"	"10.9"	"154.7"	"14.8"	"21.4"	"13.4"	"14.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NZ32"	"Actin-related protein 10 OS=Homo sapiens OX=9606 GN=ACTR10 PE=1 SV=1"	"3"	"1"	"2"	"1"	"417"	"46.3"	"7.37"	"379.19"	"2.88"	"1"	"1"	"transport"	"non-structural extracellular;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	""	"Pf00022"	"55860"	"ENSG00000131966"	"ACTR10"	"hsa:55860; Q9H9Y5; Q9NWY2; Q9NZ32"	"MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Neutrophil degranulation"	""	"5"	"0"	"39.2"	"43.1"	"152.4"	"46.0"	"54.9"	"41.7"	"174.0"	"26.4"	"45.3"	"40.4"	"34.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31949"	"Protein S100-A11 OS=Homo sapiens OX=9606 GN=S100A11 PE=1 SV=2"	"10"	"1"	"2"	"1"	"105"	"11.7"	"7.12"	"383.15"	"2.87"	"1"	"1"	"signal transduction;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00036, Pf01023"	"6282"	"ENSG00000163191"	"S100A11"	"hsa:6282; P31949; Q5VTK0"	"Neutrophil degranulation"	""	"1"	"0"	"24.0"	"13.3"	"111.7"	"14.4"	"8.1"	"9.4"	"142.3"	"4.9"	"3.4"	"7.8"	"4.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H0D6"	"5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1"	"1"	"1"	"2"	"1"	"950"	"108.5"	"7.47"	"427.09"	"2.87"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03159, Pf17846"	"22803"	"ENSG00000088930"	"XRN2"	"hsa:22803; Q3L8N4; Q6KGZ9; Q9BQL1; Q9H0D6; Q9NTW0; Q9NXS6; Q9UL53"	"Major pathway of rRNA processing in the nucleolus and cytosol; Association of TriC/CCT with target proteins during biosynthesis"	"mRNA processing"	"3"	"0"	"81.8"	"110.3"	"255.6"	"104.0"	"93.6"	"91.4"	"316.9"	"62.1"	"96.6"	"87.9"	"71.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15363"	"Transmembrane emp24 domain-containing protein 2 OS=Homo sapiens OX=9606 GN=TMED2 PE=1 SV=1"	"6"	"1"	"2"	"1"	"201"	"22.7"	"5.17"	"334.82"	"2.87"	"1"	"1"	"cell organization and biogenesis;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;ER/Golgi;other cell component"	"signal transduction activity or receptor binding"	"Pf01105"	"10959"	"ENSG00000086598"	"TMED2"	"hsa:10959; Q15363"	"COPI-mediated anterograde transport; COPI-dependent Golgi-to-ER retrograde traffic; Pre-NOTCH Processing in Golgi; COPII-mediated vesicle transport; Cargo concentration in the ER"	""	"5"	"0"	"21.5"	"12.3"	"92.5"	"12.4"	"12.8"	"9.3"	"72.9"	"4.2"	"10.7"	"7.0"	"6.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O96033"	"Molybdopterin synthase sulfur carrier subunit OS=Homo sapiens OX=9606 GN=MOCS2 PE=1 SV=1"	"13"	"1"	"2"	"1"	"88"	"9.7"	"4.72"	"254.21"	"2.87"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf02597"	"4338"	"ENSG00000164172"	"MOCS2"	"O96033"	"Molybdenum cofactor biosynthesis"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9P0M9"	"39S ribosomal protein L27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL27 PE=1 SV=1"	"23"	"3"	"4"	"3"	"148"	"16.1"	"10.42"	"907.21"	"2.87"	"3"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf01016"	"51264"	"ENSG00000108826"	"MRPL27"	"B2RE14; hsa:51264; Q9P0M9"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"149.0"	"166.2"	"466.0"	"142.5"	"110.3"	"107.2"	"605.7"	"87.7"	"123.0"	"97.7"	"111.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q06481"	"Amyloid-like protein 2 OS=Homo sapiens OX=9606 GN=APLP2 PE=1 SV=2"	"2"	"1"	"2"	"1"	"763"	"86.9"	"4.79"	"316.85"	"2.87"	"1"	"1"	"cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00014, Pf02177, Pf10515, Pf12924, Pf12925"	"334"	"ENSG00000084234"	"APLP2"	"B3KXX9; H7BXI4; hsa:334; Q06481; Q13861; Q14594; Q14662; Q71U10; Q7M4L3; Q9BT36"	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Platelet degranulation"	"Splicing factor NOVA regulated synaptic proteins"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9BR76"	"Coronin-1B OS=Homo sapiens OX=9606 GN=CORO1B PE=1 SV=1"	"3"	"1"	"2"	"1"	"489"	"54.2"	"5.88"	"421.89"	"2.86"	"1"	"1"	"cell organization and biogenesis;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400, Pf08953, Pf16300"	"57175"	"ENSG00000172725"	"CORO1B"	"B2RD45; hsa:57175; Q9BR76"	""	""	"0"	"0"	"39.6"	"43.8"	"163.1"	"54.5"	"40.0"	"30.6"	"166.4"	"27.0"	"31.9"	"31.2"	"33.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07954"	"Fumarate hydratase, mitochondrial OS=Homo sapiens OX=9606 GN=FH PE=1 SV=3"	"2"	"1"	"2"	"1"	"510"	"54.6"	"8.76"	"329.60"	"2.86"	"1"	"1"	"DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00206, Pf10415"	"2271"	"ENSG00000091483"	"FH"	"B1ANK7; hsa:2271; P07954"	"Citric acid cycle (TCA cycle)"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Krebs cycle disorders; Type 2 papillary renal cell carcinoma; Metabolic reprogramming in colon cancer; TCA cycle in senescence; TCA cycle (aka Krebs or citric acid cycle)"	"8"	"0"	"7.4"	"4.6"	"41.3"	"5.1"	"6.5"	"3.5"	"79.1"	"4.0"	"6.0"	"3.2"	"3.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NBL1"	"Protein O-glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=POGLUT1 PE=1 SV=1"	"3"	"1"	"2"	"1"	"392"	"46.2"	"8.72"	"299.46"	"2.86"	"1"	"1"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"ER/Golgi;other cell component"	"other molecular function"	"Pf05686"	"56983"	"ENSG00000163389"	"POGLUT1"	"B2RD13; hsa:56983; Q53GJ4; Q8N2T1; Q8NBL1"	"Pre-NOTCH Processing in the Endoplasmic Reticulum"	""	"1"	"0"	"8.9"	"10.9"	"28.6"	"7.0"	"7.0"	"7.4"	"23.4"	"6.1"	"11.2"	"17.0"	"20.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30044"	"Peroxiredoxin-5, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX5 PE=1 SV=4"	"12"	"2"	"3"	"2"	"214"	"22.1"	"8.70"	"907.05"	"2.86"	"2"	"1"	"other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf08534"	"25824"	"ENSG00000126432"	"PRDX5"	"A6NC19; A6NG06; B7ZLJ4; B7ZVW3; hsa:25824; P30044; Q14CK0; Q6IAF2; Q9UBU5; Q9UJU4; Q9UKX4"	""	"Selenium micronutrient network"	"1"	"0"	"140.3"	"176.1"	"909.3"	"177.9"	"134.9"	"119.0"	"1204.7"	"115.3"	"159.0"	"113.2"	"90.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WVD3"	"E3 ubiquitin-protein ligase RNF138 OS=Homo sapiens OX=9606 GN=RNF138 PE=1 SV=1"	"4"	"1"	"2"	"1"	"245"	"28.2"	"6.93"	"331.38"	"2.86"	"1"	"1"	"cell-cell signaling;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05605, Pf13923, Pf18574"	"51444"	"ENSG00000134758"	"RNF138"	"B2RE17; hsa:51444; Q8WVD3; Q9H8K2; Q9UF87; Q9UKI6"	"Antigen processing: Ubiquitination & Proteasome degradation"	""	"1"	"0"	"43.5"	"48.1"	"143.3"	"44.0"	"45.9"	"35.7"	"170.7"	"61.0"	"196.9"	"276.0"	"362.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14773"	"Tripeptidyl-peptidase 1 OS=Homo sapiens OX=9606 GN=TPP1 PE=1 SV=2"	"5"	"2"	"2"	"2"	"563"	"61.2"	"6.48"	"255.79"	"2.86"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00082, Pf09286"	"1200"	"ENSG00000166340"	"TPP1"	"hsa:1200; O14773; Q53HT1; Q5JAK6; Q6UX56; Q71JP6; Q96C37"	"XBP1(S) activates chaperone genes"	"VEGFA-VEGFR2 signaling"	"2"	"0"	"65.9"	"72.1"	"258.2"	"72.3"	"61.7"	"53.9"	"323.3"	"38.8"	"74.8"	"85.9"	"101.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96FV9"	"THO complex subunit 1 OS=Homo sapiens OX=9606 GN=THOC1 PE=1 SV=1"	"2"	"1"	"2"	"1"	"657"	"75.6"	"4.98"	"373.63"	"2.86"	"1"	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;transport;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00531, Pf11957"	"9984"	"ENSG00000079134"	"THOC1"	"B2RBP6; hsa:9984; Q15219; Q64I72; Q64I73; Q96FV9"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	""	"3"	"0"	"33.9"	"43.6"	"97.5"	"32.4"	"30.1"	"33.8"	"107.5"	"16.1"	"29.8"	"31.2"	"30.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y248"	"DNA replication complex GINS protein PSF2 OS=Homo sapiens OX=9606 GN=GINS2 PE=1 SV=1"	"7"	"1"	"2"	"1"	"185"	"21.4"	"5.44"	"278.67"	"2.86"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus"	""	"Pf05916"	"51659"	"ENSG00000131153"	"GINS2"	"D3DUM5; hsa:51659; Q6IAG9; Q9Y248"	"Unwinding of DNA"	""	"1"	"0"	"8.0"	"11.1"	"59.4"	"12.8"	"11.9"	"7.3"	"67.5"	"3.9"	"9.1"	"9.1"	"8.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16851"	"UTP--glucose-1-phosphate uridylyltransferase OS=Homo sapiens OX=9606 GN=UGP2 PE=1 SV=5"	"2"	"1"	"2"	"1"	"508"	"56.9"	"8.15"	"344.27"	"2.86"	"1"	"1"	"other metabolic processes;developmental processes"	"cytosol;other cell component"	"other molecular function"	"Pf01704"	"7360"	"ENSG00000169764"	"UGP2"	"hsa:7360; Q07131; Q0P6K2; Q16851; Q86Y81; Q9BU15"	"Glycogen synthesis; Formation of the active cofactor, UDP-glucuronate"	"Exercise-induced circadian regulation; Glycogen synthesis and degradation; Glucuronidation"	"5"	"0"	"93.6"	"128.1"	"361.4"	"112.9"	"113.8"	"109.9"	"440.4"	"82.7"	"121.3"	"91.7"	"108.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3B9"	"RRP15-like protein OS=Homo sapiens OX=9606 GN=RRP15 PE=1 SV=2"	"4"	"1"	"2"	"1"	"282"	"31.5"	"5.52"	"344.99"	"2.85"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"other cell component"	""	"Pf07890"	"51018"	"ENSG00000067533"	"RRP15"	"hsa:51018; Q9Y3B9"	""	""	"0"	"0"	"9.8"	"12.2"	"44.6"	"19.7"	"14.8"	"12.7"	"46.4"	"6.4"	"13.1"	"11.6"	"6.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4B6"	"DDB1- and CUL4-associated factor 1 OS=Homo sapiens OX=9606 GN=DCAF1 PE=1 SV=3"	"1"	"1"	"2"	"1"	"1507"	"168.9"	"5.06"	"279.56"	"2.85"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	""	"9730"	"ENSG00000145041"	"DCAF1"	"hsa:9730; Q2YD74; Q8TBD9; Q9HCA1; Q9UG37; Q9Y4B6"	"Antigen processing: Ubiquitination & Proteasome degradation"	"Hippo-Merlin signaling dysregulation"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H8H2"	"Probable ATP-dependent RNA helicase DDX31 OS=Homo sapiens OX=9606 GN=DDX31 PE=1 SV=2"	"2"	"1"	"2"	"1"	"851"	"94.0"	"9.99"	"365.97"	"2.85"	"1"	"1"	"other biological processes"	"ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271, Pf13959"	"64794"	"ENSG00000125485"	"DDX31"	"hsa:64794; Q5K6N2; Q5K6N3; Q5K6N4; Q5VZJ4; Q5VZJ9; Q96E91; Q96NY2; Q96SX5; Q9H5K6; Q9H8H2"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q14574"	"Desmocollin-3 OS=Homo sapiens OX=9606 GN=DSC3 PE=1 SV=3"	"2"	"1"	"2"	"1"	"896"	"99.9"	"6.10"	"347.14"	"2.85"	"1"	"1"	"cell adhesion;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00028, Pf01049, Pf08758"	"1825"	"ENSG00000134762"	"DSC3"	"A6NN35; hsa:1825; Q14200; Q14574; Q9HAZ9"	"Formation of the cornified envelope"	"Pleural mesothelioma"	"3"	"0"	"86.7"	"63.0"	"59.8"	"16.3"	"11.7"	"11.3"	"58.0"	"11.4"	"5.4"	"8.2"	"11.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P54709"	"Sodium/potassium-transporting ATPase subunit beta-3 OS=Homo sapiens OX=9606 GN=ATP1B3 PE=1 SV=1"	"4"	"1"	"2"	"1"	"279"	"31.5"	"8.35"	"310.56"	"2.85"	"1"	"1"	"transport;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"other molecular function"	"Pf00287"	"483"	"ENSG00000069849"	"ATP1B3"	"B7Z1N7; hsa:483; P54709"	"Potential therapeutics for SARS; Ion homeostasis; Ion transport by P-type ATPases; Basigin interactions"	"Calcium regulation in cardiac cells"	"5"	"0"	"121.9"	"118.4"	"635.1"	"102.5"	"92.1"	"56.0"	"562.3"	"46.0"	"52.9"	"49.7"	"64.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09669"	"Cytochrome c oxidase subunit 6C OS=Homo sapiens OX=9606 GN=COX6C PE=1 SV=2"	"11"	"1"	"2"	"1"	"75"	"8.8"	"10.39"	"305.79"	"2.84"	"1"	"1"	"other metabolic processes"	"other membranes;mitochondrion"	""	"Pf02937"	"1345"	"ENSG00000164919"	"COX6C"	"B2R4D7; hsa:1345; P09669"	"TP53 Regulates Metabolic Genes; Respiratory electron transport; Cytoprotection by HMOX1"	"Electron transport chain: OXPHOS system in mitochondria; Ciliary landscape; Nonalcoholic fatty liver disease; Mitochondrial complex IV assembly"	"7"	"0"	"199.1"	"224.9"	"906.5"	"175.7"	"139.3"	"92.1"	"949.0"	"70.4"	"101.8"	"65.4"	"66.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35221"	"Catenin alpha-1 OS=Homo sapiens OX=9606 GN=CTNNA1 PE=1 SV=1"	"1"	"1"	"2"	"1"	"906"	"100.0"	"6.29"	"311.63"	"2.83"	"1"	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01044"	"1495"	"ENSG00000044115"	"CTNNA1"	"hsa:1495; P35221; Q12795; Q8N1C0"	"RHO GTPases activate IQGAPs; Myogenesis; VEGFR2 mediated vascular permeability; Adherens junctions interactions; Regulation of CDH11 function; Regulation of CDH19 Expression and Function; CDH11 homotypic and heterotypic interactions"	"Arrhythmogenic right ventricular cardiomyopathy; Apoptosis-related network due to altered Notch3 in ovarian cancer; VEGFA-VEGFR2 signaling; White fat cell differentiation; Endometrial cancer; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-Merlin signaling dysregulation; Pleural mesothelioma"	"15"	"0"	"6.7"	"8.9"	"47.4"	"10.6"	"6.5"	"7.1"	"36.8"	"3.3"	"3.3"	"4.1"	"4.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y315"	"Deoxyribose-phosphate aldolase OS=Homo sapiens OX=9606 GN=DERA PE=1 SV=2"	"3"	"1"	"2"	"1"	"318"	"35.2"	"8.94"	"259.09"	"2.83"	"1"	"1"	"other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf01791"	"51071"	"ENSG00000023697"	"DERA"	"hsa:51071; Q53HN9; Q6PHW2; Q9Y315"	"Neutrophil degranulation; Pentose phosphate pathway"	"Pentose phosphate pathway in senescent cells"	"3"	"0"	"49.4"	"58.5"	"119.8"	"54.1"	"47.7"	"35.2"	"149.4"	"38.3"	"36.2"	"32.4"	"36.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HD67"	"Unconventional myosin-X OS=Homo sapiens OX=9606 GN=MYO10 PE=1 SV=3"	"0"	"1"	"2"	"1"	"2058"	"237.2"	"6.21"	"265.42"	"2.82"	"1"	"1"	"transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00063, Pf00169, Pf00373, Pf00612, Pf00784, Pf00788, Pf16735, Pf18597"	"4651"	"ENSG00000145555"	"MYO10"	"A7E2D1; hsa:4651; O94893; Q8IVX5; Q9HD67; Q9NYM7; Q9P110; Q9P111; Q9UHF6"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; Netrin-1 signaling"	""	"3"	"0"	"194.8"	"177.5"	"654.5"	"198.4"	"163.7"	"131.1"	"518.9"	"78.0"	"165.3"	"128.9"	"135.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43747"	"AP-1 complex subunit gamma-1 OS=Homo sapiens OX=9606 GN=AP1G1 PE=1 SV=5"	"3"	"2"	"3"	"2"	"822"	"91.3"	"6.80"	"676.85"	"2.82"	"2"	"1"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01602, Pf02883"	"164"	"ENSG00000166747"	"AP1G1"	"hsa:164; O43747; O75709; O75842; Q9UG09; Q9Y3U4"	"MHC class II antigen presentation; Lysosome Vesicle Biogenesis; Golgi Associated Vesicle Biogenesis; Nef mediated downregulation of MHC class I complex cell surface expression"	""	"4"	"0"	"15.6"	"13.0"	"47.9"	"16.2"	"13.4"	"15.8"	"45.5"	"5.1"	"12.9"	"13.5"	"6.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NRG9"	"Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1"	"2"	"1"	"2"	"1"	"546"	"59.5"	"7.50"	"379.49"	"2.82"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus"	""	"Pf00400"	"8086"	"ENSG00000094914"	"AAAS"	"hsa:8086; Q5JB47; Q9NRG9; Q9NWI6; Q9UG19"	"RHOA GTPase cycle; ISG15 antiviral mechanism; SARS-CoV-2 activates/modulates innate and adaptive immune responses; tRNA processing in the nucleus; HCMV Late Events; HCMV Early Events; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"	""	"29"	"0"	"47.0"	"40.3"	"171.8"	"40.1"	"29.5"	"25.5"	"165.9"	"16.2"	"27.3"	"16.4"	"13.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P42695"	"Condensin-2 complex subunit D3 OS=Homo sapiens OX=9606 GN=NCAPD3 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1498"	"168.8"	"7.50"	"411.98"	"2.82"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf12717"	"23310"	"ENSG00000151503"	"NCAPD3"	"A6NFS2; hsa:23310; P42695; Q4KMQ9"	"Condensation of Prophase Chromosomes"	""	"1"	"0"	"24.3"	"26.3"	"114.5"	"26.3"	"30.6"	"20.7"	"103.9"	"13.6"	"16.2"	"10.6"	"12.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14828"	"Secretory carrier-associated membrane protein 3 OS=Homo sapiens OX=9606 GN=SCAMP3 PE=1 SV=3"	"4"	"1"	"2"	"1"	"347"	"38.3"	"7.64"	"356.85"	"2.81"	"1"	"1"	"transport"	"other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf04144"	"10067"	"ENSG00000116521; ENSG00000263290"	"SCAMP3"	"A9Z1W6; B1AVS6; hsa:10067; O14828; O15128; Q96FR8; Q9BPY0"	""	""	"0"	"0"	"17.2"	"9.5"	"33.0"	"10.3"	"6.5"	"5.1"	"30.0"	"4.3"	"4.9"	"4.2"	"4.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5R3I4"	"Tetratricopeptide repeat protein 38 OS=Homo sapiens OX=9606 GN=TTC38 PE=1 SV=1"	"2"	"1"	"2"	"1"	"469"	"52.8"	"5.99"	"311.59"	"2.81"	"1"	"1"	""	""	""	""	"55020"	"ENSG00000075234"	"TTC38"	"hsa:55020; Q5R3I4; Q8WV27; Q9NWP8"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23368"	"NAD-dependent malic enzyme, mitochondrial OS=Homo sapiens OX=9606 GN=ME2 PE=1 SV=1"	"3"	"2"	"3"	"2"	"584"	"65.4"	"7.61"	"592.31"	"2.81"	"2"	"1"	"other metabolic processes;other biological processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf00390, Pf03949"	"4200"	"ENSG00000082212"	"ME2"	"B2R8J2; hsa:4200; P23368; Q9BWL6; Q9BYG1; Q9H4B2"	"Citric acid cycle (TCA cycle)"	"TCA cycle in senescence"	"2"	"0"	"91.3"	"118.6"	"438.3"	"108.3"	"104.3"	"84.2"	"503.4"	"84.8"	"125.3"	"174.8"	"305.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y6X5"	"Bis(5'-adenosyl)-triphosphatase ENPP4 OS=Homo sapiens OX=9606 GN=ENPP4 PE=1 SV=3"	"3"	"1"	"2"	"1"	"453"	"51.6"	"6.15"	"285.18"	"2.81"	"1"	"1"	"other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes"	"other molecular function"	"Pf01663"	"22875"	"ENSG00000001561"	"ENPP4"	"A8K5G1; hsa:22875; Q7L2N1; Q9Y6X5"	"Neutrophil degranulation"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NRX1"	"RNA-binding protein PNO1 OS=Homo sapiens OX=9606 GN=PNO1 PE=1 SV=1"	"11"	"2"	"3"	"2"	"252"	"27.9"	"9.73"	"598.57"	"2.79"	"2"	"1"	"other biological processes"	"cytosol;nucleus;other cell component"	""	""	"56902"	"ENSG00000115946"	"PNO1"	"A8K6Q0; hsa:56902; Q53G13; Q8WVB8; Q9NRX1"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	"8.2"	"9.1"	"40.9"	"11.1"	"6.8"	"6.1"	"43.2"	"3.0"	"1.7"	"4.4"	"5.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5PRF9"	"Protein Smaug homolog 2 OS=Homo sapiens OX=9606 GN=SAMD4B PE=1 SV=1"	"2"	"1"	"2"	"1"	"694"	"75.4"	"6.83"	"440.83"	"2.79"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00536"	"55095"	"ENSG00000179134"	"SAMD4B"	"A5Z0M6; hsa:55095; Q5PRF9; Q6P194"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"P02786"	"Transferrin receptor protein 1 OS=Homo sapiens OX=9606 GN=TFRC PE=1 SV=2"	"1"	"1"	"2"	"1"	"760"	"84.8"	"6.61"	"327.62"	"2.79"	"1"	"1"	"stress response;transport;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02225, Pf04253, Pf04389"	"7037"	"ENSG00000072274"	"TFRC"	"D3DXB0; hsa:7037; P02786; Q1HE24; Q59G55; Q9UCN0; Q9UCU5; Q9UDF9; Q9UK21"	"RHOC GTPase cycle; RND2 GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOB GTPase cycle; RHOJ GTPase cycle; Golgi Associated Vesicle Biogenesis; RND1 GTPase cycle; Cargo recognition for clathrin-mediated endocytosis; Transferrin endocytosis and recycling; RHOH GTPase cycle"	"Iron metabolism in placenta; Ferroptosis; 3q29 copy number variation syndrome; Iron metabolism disorders"	"21"	"0"	"19.5"	"13.9"	"70.3"	"10.5"	"14.6"	"6.5"	"70.3"	"2.9"	"9.7"	"8.6"	"10.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H115"	"Beta-soluble NSF attachment protein OS=Homo sapiens OX=9606 GN=NAPB PE=1 SV=2"	"4"	"1"	"2"	"1"	"298"	"33.5"	"5.47"	"381.42"	"2.79"	"1"	"1"	"cell-cell signaling;cell organization and biogenesis;transport;other biological processes"	"other membranes;other cell component"	"other molecular function"	"Pf14938"	"63908"	"ENSG00000125814"	"NAPB"	"B4DK44; hsa:63908; Q4G0M0; Q4G187; Q5JXF9; Q8N3C4; Q9H115"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport; Retrograde transport at the Trans-Golgi-Network; Intra-Golgi traffic; COPII-mediated vesicle transport"	""	"5"	"0"	"15.0"	"13.5"	"97.5"	"17.8"	"10.6"	"9.1"	"102.1"	"8.4"	"6.6"	"8.2"	"9.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UJV9"	"Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2"	"2"	"1"	"2"	"1"	"622"	"69.8"	"6.84"	"312.18"	"2.79"	"1"	"1"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00270, Pf00271"	"51428"	"ENSG00000183258"	"DDX41"	"B2RDC8; hsa:51428; Q96BK6; Q96K05; Q9NT96; Q9NW04; Q9UJV9"	"mRNA Splicing - Major Pathway; Regulation of innate immune responses to cytosolic DNA; IRF3-mediated induction of type I IFN"	""	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q07812"	"Apoptosis regulator BAX OS=Homo sapiens OX=9606 GN=BAX PE=1 SV=1"	"6"	"1"	"2"	"1"	"192"	"21.2"	"5.22"	"245.23"	"2.78"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;mitochondrion;ER/Golgi;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf00452"	"581"	"ENSG00000087088"	"BAX"	"A8K4W1; hsa:581; P55269; Q07812; Q07814; Q07815; Q8WZ49; Q9NR76; Q9NYG7; Q9UCZ6; Q9UCZ7; Q9UQD6"	"Release of apoptotic factors from the mitochondria; Pyroptosis; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Transcriptional regulation by RUNX2; TP53 Regulates Transcription of Genes Involved in Cytochrome C Release; Activation, translocation and oligomerization of BAX; NTRK3 as a dependence receptor"	"miRNA regulation of DNA damage response; TP53 network; Leptin signaling pathway; TNF-alpha signaling pathway; Amyotrophic lateral sclerosis (ALS); Nanomaterial induced apoptosis; Apoptosis; Mammary gland development pathway - Involution (Stage 4 of 4); Aryl hydrocarbon receptor pathway; Nuclear receptors meta-pathway; Overview of nanoparticle effects; RAC1/PAK1/p38/MMP2 pathway; Photodynamic therapy-induced HIF-1 survival signaling; Regulation of apoptosis by parathyroid hormone-related protein; miRNA regulation of p53 pathway in prostate cancer; Endometrial cancer; Chromosomal and microsatellite instability in colorectal cancer ; Non-small cell lung cancer; Breast cancer pathway; Pancreatic adenocarcinoma pathway; Acute viral myocarditis; Nonalcoholic fatty liver disease; Measles virus infection; Small cell lung cancer; Hepatitis B infection; Melanoma; IL-18 signaling pathway; EGFR tyrosine kinase inhibitor resistance; Regucalcin in proximal tubule epithelial kidney cells; Host-pathogen interaction of human coronaviruses - apoptosis; Peroxiredoxin 2 induced ovarian failure; p53 transcriptional gene network; Pleural mesothelioma; Complement system in neuronal development and plasticity; Urotensin-II-mediated signaling pathway; TROP2 regulatory signaling; CKAP4 signaling pathway map; IL-26 signaling pathways; DNA damage response; DNA damage response (only ATM dependent)"	"47"	"0"	"11.5"	"10.7"	"48.5"	"12.5"	"8.2"	"6.4"	"61.0"	"4.3"	"8.8"	"7.5"	"3.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50995"	"Annexin A11 OS=Homo sapiens OX=9606 GN=ANXA11 PE=1 SV=1"	"4"	"2"	"3"	"2"	"505"	"54.4"	"7.65"	"542.31"	"2.78"	"2"	"1"	"cell cycle OR cell proliferation;transport;other biological processes"	"cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00191"	"311"	"ENSG00000122359"	"ANXA11"	"B4DVE7; hsa:311; P50995"	""	""	"0"	"0"	"155.0"	"200.8"	"468.5"	"222.2"	"200.4"	"166.1"	"544.0"	"170.2"	"246.3"	"212.8"	"217.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96HE7"	"ERO1-like protein alpha OS=Homo sapiens OX=9606 GN=ERO1A PE=1 SV=2"	"2"	"1"	"3"	"1"	"468"	"54.4"	"5.68"	"893.32"	"2.78"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"non-structural extracellular;other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf04137"	"30001"	"ENSG00000197930"	"ERO1A"	"A8K9X4; A8MYW1; hsa:30001; Q7LD45; Q96HE7; Q9P1Q9; Q9UKV6"	"Detoxification of Reactive Oxygen Species"	""	"1"	"0"	"4.1"	"3.6"	"48.7"	"7.6"	"5.4"	"2.7"	"69.5"	"2.1"	"0.0"	"0.0"	"0.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q96JJ7"	"Protein disulfide-isomerase TMX3 OS=Homo sapiens OX=9606 GN=TMX3 PE=1 SV=2"	"6"	"2"	"3"	"2"	"454"	"51.8"	"4.91"	"905.88"	"2.77"	"2"	"1"	"protein metabolism;other metabolic processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf00085, Pf13848"	"54495"	"ENSG00000166479"	"TMX3"	"B3KV75; hsa:54495; Q52LT7; Q8N5J0; Q96JJ7; Q9NWJ9"	"Platelet degranulation"	""	"1"	"0"	"39.7"	"35.4"	"138.2"	"32.8"	"31.8"	"30.8"	"167.1"	"19.8"	"32.6"	"27.6"	"21.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q07866"	"Kinesin light chain 1 OS=Homo sapiens OX=9606 GN=KLC1 PE=1 SV=2"	"3"	"1"	"2"	"1"	"573"	"65.3"	"6.20"	"494.08"	"2.77"	"1"	"1"	"cell adhesion;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf00515, Pf13374, Pf13424"	"3831"	"ENSG00000126214"	"KLC1"	"A6NF62; F8VTM4; hsa:3831; Q07866; Q7RTM2; Q7RTM3; Q7RTM5; Q7RTP9; Q7RTQ3; Q7RTQ5; Q7RTQ6; Q86SF5; Q86TF5; Q86V74; Q86V75; Q86V76; Q86V77; Q86V78; Q86V79; Q96H62"	"MHC class II antigen presentation; Signaling by ALK fusions and activated point mutants; COPI-dependent Golgi-to-ER retrograde traffic; Kinesins; RHO GTPases activate KTN1"	"Alzheimer's disease and miRNA effects; IL-18 signaling pathway; Alzheimer's disease"	"8"	"0"	"27.2"	"30.6"	"127.0"	"23.4"	"22.5"	"13.6"	"162.7"	"8.8"	"24.5"	"16.4"	"10.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O96008"	"Mitochondrial import receptor subunit TOM40 homolog OS=Homo sapiens OX=9606 GN=TOMM40 PE=1 SV=1"	"3"	"1"	"2"	"1"	"361"	"37.9"	"7.25"	"268.35"	"2.77"	"1"	"1"	"cell organization and biogenesis;transport"	"other membranes;cytosol;mitochondrion;other cell component"	"transporter activity"	"Pf01459"	"10452"	"ENSG00000130204"	"TOMM40"	"A0A024R0P9; hsa:10452; O96008; Q86VW4; Q8WY09; Q8WY10; Q8WY11; Q9BR95"	"Mitochondrial protein import; PINK1-PRKN Mediated Mitophagy"	"IL-18 signaling pathway"	"3"	"0"	"10.8"	"6.1"	"41.4"	"5.9"	"5.1"	"1.5"	"38.0"	"0.0"	"3.7"	"0.0"	"0.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"O43399"	"Tumor protein D54 OS=Homo sapiens OX=9606 GN=TPD52L2 PE=1 SV=2"	"8"	"2"	"3"	"2"	"206"	"22.2"	"5.36"	"500.91"	"2.77"	"2"	"1"	"other metabolic processes;other biological processes"	"other cell component"	"other molecular function"	"Pf04201"	"7165"	"ENSG00000101150"	"TPD52L2"	"B4DPJ6; E1P5G7; hsa:7165; O43398; O43399; Q5JWU5; Q5JWU6; Q5JWU8; Q5U0E0; Q9H3Z6"	""	""	"0"	"0"	"161.4"	"175.5"	"749.1"	"144.2"	"129.9"	"108.3"	"689.6"	"81.3"	"111.4"	"78.8"	"96.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NUW8"	"Tyrosyl-DNA phosphodiesterase 1 OS=Homo sapiens OX=9606 GN=TDP1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"608"	"68.4"	"7.65"	"231.70"	"2.76"	"1"	"1"	"DNA metabolism;other metabolic processes;stress response"	"plasma membrane;other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06087"	"55775"	"ENSG00000042088"	"TDP1"	"hsa:55775; Q2HXX4; Q86TV8; Q96BK7; Q9NUW8; Q9NZM7; Q9NZM8"	"Nonhomologous End-Joining (NHEJ)"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96GM8"	"Target of EGR1 protein 1 OS=Homo sapiens OX=9606 GN=TOE1 PE=1 SV=1"	"2"	"1"	"2"	"1"	"510"	"56.5"	"7.18"	"237.07"	"2.76"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00642, Pf04857"	"114034"	"ENSG00000132773"	"TOE1"	"B4DEM6; hsa:114034; Q6IA35; Q8IWN5; Q96GM8; Q9H846"	""	""	"0"	"0"	"26.6"	"22.4"	"58.5"	"21.1"	"25.3"	"16.8"	"50.3"	"7.4"	"12.7"	"10.8"	"10.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15276"	"Rab GTPase-binding effector protein 1 OS=Homo sapiens OX=9606 GN=RABEP1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"862"	"99.2"	"5.01"	"233.01"	"2.76"	"1"	"1"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"other membranes;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf03528, Pf09311"	"9135"	"ENSG00000029725"	"RABEP1"	"B2RAG7; hsa:9135; O95369; Q15276; Q8IVX3"	"TBC/RABGAPs"	"GDNF signaling"	"2"	"0"	"14.3"	"13.8"	"60.1"	"20.5"	"11.6"	"13.7"	"67.2"	"9.4"	"14.9"	"10.4"	"8.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15019"	"Septin-2 OS=Homo sapiens OX=9606 GN=SEPTIN2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"361"	"41.5"	"6.60"	"378.66"	"2.76"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00735"	"4735"	"ENSG00000168385"	"SEPTIN2"	"B4DGE8; hsa:4735; Q14132; Q15019; Q53QU3; Q8IUK9; Q96CB0"	"Anchoring of the basal body to the plasma membrane"	"2q37 copy number variation syndrome"	"2"	"0"	"150.6"	"163.9"	"586.9"	"161.1"	"98.9"	"108.8"	"286.0"	"40.5"	"62.4"	"62.0"	"71.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75386"	"Tubby-related protein 3 OS=Homo sapiens OX=9606 GN=TULP3 PE=1 SV=2"	"4"	"1"	"1"	"1"	"442"	"49.6"	"7.74"	""	"2.76"	""	"1"	"developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01167, Pf16322"	"7289"	"ENSG00000078246"	"TULP3"	"B3KNB7; B7Z6A2; D3DUQ4; F8WBZ9; hsa:7289; O75386; Q8N5B0"	"Hedgehog 'off' state"	"H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity; Genes related to primary cilium development (based on CRISPR)"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60234"	"Glia maturation factor gamma OS=Homo sapiens OX=9606 GN=GMFG PE=1 SV=1"	"6"	"1"	"2"	"1"	"142"	"16.8"	"5.26"	"395.69"	"2.76"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"non-structural extracellular;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00241"	"9535"	"ENSG00000130755"	"GMFG"	"hsa:9535; O60234; Q6IB37"	"Neutrophil degranulation"	""	"1"	"0"	"66.1"	"65.2"	"266.5"	"69.1"	"64.7"	"46.0"	"394.0"	"44.5"	"65.8"	"54.8"	"40.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TE49"	"OTU domain-containing protein 7A OS=Homo sapiens OX=9606 GN=OTUD7A PE=1 SV=1"	"1"	"1"	"2"	"1"	"926"	"100.6"	"8.40"	"332.39"	"2.76"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01754, Pf02338, Pf14555"	"161725"	"ENSG00000169918"	"OTUD7A"	"hsa:161725; Q8IWK5; Q8TE49"	"Ovarian tumor domain proteases"	"15q13.3 copy number variation syndrome"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UMX5"	"Neudesin OS=Homo sapiens OX=9606 GN=NENF PE=1 SV=1"	"6"	"1"	"2"	"1"	"172"	"18.8"	"5.69"	"323.31"	"2.75"	"1"	"1"	"signal transduction;other biological processes"	"non-structural extracellular;other membranes;mitochondrion;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00173"	"29937"	"ENSG00000117691"	"NENF"	"A1KYQ8; hsa:29937; Q53FZ6; Q5TM90; Q9UMX5"	""	""	"0"	"0"	"8.6"	"9.0"	"78.9"	"6.3"	"6.6"	"0.0"	"116.2"	"4.9"	"1.2"	"0.0"	"0.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"O94874"	"E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"794"	"89.5"	"6.79"	"287.18"	"2.75"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf09743"	"23376"	"ENSG00000014123"	"UFL1"	"A0PJ53; B4DJ57; C0H5X5; hsa:23376; O94874; Q8N765; Q9NTQ0"	"Antigen processing: Ubiquitination & Proteasome degradation"	""	"1"	"0"	"47.1"	"49.6"	"156.1"	"43.1"	"35.0"	"23.2"	"163.5"	"27.3"	"25.5"	"21.9"	"27.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q02880"	"DNA topoisomerase 2-beta OS=Homo sapiens OX=9606 GN=TOP2B PE=1 SV=3"	"1"	"1"	"2"	"1"	"1626"	"183.2"	"8.00"	"346.36"	"2.75"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00204, Pf00521, Pf01751, Pf02518, Pf08070, Pf16898"	"7155"	"ENSG00000077097"	"TOP2B"	"hsa:7155; Q02880; Q13600; Q9UMG8; Q9UQP8"	"SUMOylation of DNA replication proteins"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9UBU9"	"Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1"	"2"	"1"	"2"	"1"	"619"	"70.1"	"8.51"	"379.37"	"2.75"	"1"	"1"	"other metabolic processes;transport"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf02136, Pf03943, Pf09162"	"10482"	"ENSG00000162231"	"NXF1"	"B4E269; hsa:10482; Q99799; Q9UBU9; Q9UQL2"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript"	"mRNA processing"	"5"	"0"	"18.4"	"17.7"	"68.6"	"19.6"	"19.9"	"14.3"	"42.4"	"5.9"	"11.2"	"9.7"	"7.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O76031"	"ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial OS=Homo sapiens OX=9606 GN=CLPX PE=1 SV=2"	"2"	"1"	"2"	"1"	"633"	"69.2"	"7.58"	"336.06"	"2.74"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;cytosol;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf07724, Pf10431"	"10845"	"ENSG00000166855"	"CLPX"	"A1L428; A8K8F1; B9EGI8; hsa:10845; O76031; Q9H4D9"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5T0F9"	"Coiled-coil and C2 domain-containing protein 1B OS=Homo sapiens OX=9606 GN=CC2D1B PE=1 SV=1"	"1"	"1"	"2"	"1"	"858"	"94.2"	"5.26"	"293.82"	"2.74"	"1"	"1"	"RNA metabolism OR transcription;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00168"	"200014"	"ENSG00000154222"	"CC2D1B"	"hsa:200014; Q49AE8; Q5T0F8; Q5T0F9; Q5T0G0; Q6ZNQ1; Q96AP3; Q96I04; Q96JJ1"	"Sealing of the nuclear envelope (NE) by ESCRT-III"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q92882"	"Osteoclast-stimulating factor 1 OS=Homo sapiens OX=9606 GN=OSTF1 PE=1 SV=2"	"6"	"1"	"2"	"1"	"214"	"23.8"	"5.68"	"325.02"	"2.74"	"1"	"1"	"signal transduction;other biological processes"	"other cell component"	"other molecular function"	"Pf00018, Pf12796"	"26578"	"ENSG00000134996"	"OSTF1"	"hsa:26578; Q5W126; Q92882; Q96IJ4"	"Neutrophil degranulation"	""	"1"	"0"	"11.8"	"21.1"	"64.7"	"20.7"	"17.3"	"8.9"	"86.5"	"15.9"	"18.7"	"14.2"	"10.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NF91"	"Nesprin-1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=4"	"0"	"2"	"2"	"1"	"8797"	"1010.5"	"5.53"	"248.12"	"2.74"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00435, Pf10541"	"23345"	"ENSG00000131018"	"SYNE1"	"B3W695; E7EQI5; H0Y4C0; hsa:23345; O94890; Q3ZCV0; Q5JV19; Q5JV22; Q8N9P7; Q8NF91; Q8TCP1; Q8WWW6; Q8WWW7; Q8WXF6; Q96N17; Q9C0A7; Q9H525; Q9H526; Q9NS36; Q9NU50; Q9UJ06; Q9UJ07; Q9ULF8"	"Meiotic synapsis"	"Envelope proteins and their potential roles in EDMD physiopathology"	"2"	"0"	"11.6"	"21.8"	"82.6"	"14.4"	"12.0"	"11.6"	"128.7"	"30.9"	"40.9"	"48.5"	"144.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q3LXA3"	"Triokinase/FMN cyclase OS=Homo sapiens OX=9606 GN=TKFC PE=1 SV=2"	"2"	"1"	"2"	"1"	"575"	"58.9"	"7.49"	"254.48"	"2.73"	"1"	"1"	"other metabolic processes;other biological processes"	"cytosol"	"kinase activity;other molecular function"	"Pf02733, Pf02734"	"26007"	"ENSG00000149476"	"TKFC"	"hsa:26007; Q2L9C1; Q3LXA3; Q53EQ9; Q9BVA7; Q9H895"	"SARS-CoV-2 activates/modulates innate and adaptive immune responses; DDX58/IFIH1-mediated induction of interferon-alpha/beta; SARS-CoV-1 activates/modulates innate immune responses; Fructose catabolism"	"Novel intracellular components of RIG-I-like receptor pathway"	"5"	"0"	"8.1"	"4.8"	"41.6"	"7.6"	"6.8"	"4.9"	"61.7"	"6.4"	"5.7"	"8.5"	"6.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P48147"	"Prolyl endopeptidase OS=Homo sapiens OX=9606 GN=PREP PE=1 SV=2"	"3"	"2"	"3"	"2"	"710"	"80.6"	"5.86"	"681.53"	"2.73"	"2"	"1"	"protein metabolism"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00326, Pf02897"	"5550"	"ENSG00000085377"	"PREP"	"hsa:5550; P48147; Q8N6D4"	""	""	"0"	"0"	"33.5"	"33.7"	"118.4"	"32.9"	"30.2"	"20.0"	"139.2"	"16.5"	"27.7"	"17.6"	"18.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00233"	"26S proteasome non-ATPase regulatory subunit 9 OS=Homo sapiens OX=9606 GN=PSMD9 PE=1 SV=3"	"10"	"2"	"2"	"2"	"223"	"24.7"	"6.95"	"436.82"	"2.73"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf02163, Pf17820, Pf18265"	"5715"	"ENSG00000110801"	"PSMD9"	"B2RD35; G3V1Q6; hsa:5715; O00233; Q9BQ42"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"63"	"0"	"93.8"	"98.5"	"361.5"	"104.2"	"118.4"	"86.2"	"457.1"	"79.7"	"118.7"	"113.5"	"108.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15910"	"Histone-lysine N-methyltransferase EZH2 OS=Homo sapiens OX=9606 GN=EZH2 PE=1 SV=2"	"2"	"1"	"2"	"1"	"746"	"85.3"	"7.02"	"267.67"	"2.73"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00856, Pf11616, Pf18118, Pf18264"	"2146"	"ENSG00000106462"	"EZH2"	"B2RAQ1; B3KS30; B7Z1D6; B7Z7L6; hsa:2146; Q15755; Q15910; Q75MG3; Q92857; Q96FI6"	"Defective pyroptosis; Oxidative Stress Induced Senescence; HCMV Early Events; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6; Activation of anterior HOX genes in hindbrain development during early embryogenesis; PKMTs methylate histone lysines; PRC2 methylates histones and DNA"	"Cell differentiation - expanded index; Histone modifications; Endoderm differentiation; Interactome of polycomb repressive complex 2 (PRC2) ; MECP2 and associated Rett syndrome; Tumor suppressor activity of SMARCB1; Epithelial to mesenchymal transition in colorectal cancer; lncRNA in canonical Wnt signaling and colorectal cancer; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; Pleural mesothelioma"	"19"	"0"	"11.0"	"11.0"	"38.8"	"8.5"	"11.7"	"9.5"	"43.2"	"5.8"	"6.6"	"7.6"	"6.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q3ZCW2"	"Galectin-related protein OS=Homo sapiens OX=9606 GN=LGALSL PE=1 SV=2"	"6"	"1"	"1"	"1"	"172"	"19.0"	"5.35"	""	"2.73"	""	"1"	""	""	"other molecular function"	"Pf00337"	"29094"	"ENSG00000119862"	"LGALSL"	"B2RBG8; D6W5E8; hsa:29094; Q3ZCW2; Q6P5T6; Q9P005"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15228"	"Dihydroxyacetone phosphate acyltransferase OS=Homo sapiens OX=9606 GN=GNPAT PE=1 SV=1"	"2"	"1"	"2"	"1"	"680"	"77.1"	"6.57"	"308.63"	"2.73"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;stress response;developmental processes;other biological processes"	"other membranes;cytosol;mitochondrion;other cytoplasmic organelle"	"other molecular function"	"Pf01553, Pf19277"	"8443"	"ENSG00000116906"	"GNPAT"	"B4DNM9; hsa:8443; O15228; Q5TBH7; Q9BWC2"	"Peroxisomal protein import; Plasmalogen biosynthesis; Synthesis of PA"	"Triacylglyceride synthesis"	"4"	"0"	"4.9"	"2.0"	"37.9"	"4.8"	"2.1"	"2.4"	"51.0"	"0.0"	"6.2"	"0.0"	"0.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q8NDI1"	"EH domain-binding protein 1 OS=Homo sapiens OX=9606 GN=EHBP1 PE=1 SV=3"	"1"	"2"	"3"	"1"	"1231"	"139.9"	"5.35"	"534.70"	"2.73"	"2"	"1"	"transport"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle"	""	"Pf00307, Pf10358, Pf12130"	"23301"	"ENSG00000115504"	"EHBP1"	"hsa:23301; O94977; Q53TG7; Q53TV6; Q580X2; Q6NX72; Q6PIT3; Q6QNV2; Q8NDI1; Q9NWI9"	""	"Ciliary landscape"	"1"	"1"	"100.8"	"139.0"	"1025.5"	"105.8"	"72.3"	"54.9"	"1725.2"	"100.6"	"63.4"	"62.9"	"53.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99453"	"Paired mesoderm homeobox protein 2B OS=Homo sapiens OX=9606 GN=PHOX2B PE=1 SV=2"	"3"	"1"	"2"	"1"	"314"	"31.6"	"8.84"	"403.80"	"2.72"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00046"	"8929"	"ENSG00000109132"	"PHOX2B"	"hsa:8929; Q6PJD9; Q99453"	""	"Neural crest differentiation; Sudden infant death syndrome (SIDS) susceptibility pathways"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96J84"	"Kin of IRRE-like protein 1 OS=Homo sapiens OX=9606 GN=KIRREL1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"757"	"83.5"	"5.73"	"265.84"	"2.72"	"1"	"1"	"cell adhesion;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;other cell component"	"cytoskeletal activity;other molecular function"	"Pf07679, Pf08205, Pf13927"	"55243"	"ENSG00000183853"	"KIRREL1"	"hsa:55243; Q5W0F8; Q5XKC6; Q7Z696; Q7Z7N8; Q8TB15; Q96J84; Q9H9N1; Q9NVA5"	"Nephrin family interactions"	"Genes controlling nephrogenesis; 1q21.1 copy number variation syndrome"	"3"	"0"	"8.7"	"8.4"	"27.8"	"5.0"	"10.0"	"6.9"	"44.9"	"3.7"	"9.9"	"6.4"	"7.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HDC9"	"Adipocyte plasma membrane-associated protein OS=Homo sapiens OX=9606 GN=APMAP PE=1 SV=2"	"2"	"1"	"2"	"1"	"416"	"46.5"	"6.16"	"354.05"	"2.71"	"1"	"1"	"other metabolic processes"	"other membranes;other cell component"	"other molecular function"	"Pf03088, Pf20067"	"57136"	"ENSG00000101474"	"APMAP"	"A8K514; B4DXG1; hsa:57136; Q6UVZ8; Q9GZS8; Q9HDC9; Q9NUB2"	""	"Ciliary landscape"	"1"	"0"	"46.2"	"54.2"	"284.2"	"46.4"	"48.5"	"32.7"	"351.1"	"20.7"	"37.1"	"33.4"	"32.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BXS5"	"AP-1 complex subunit mu-1 OS=Homo sapiens OX=9606 GN=AP1M1 PE=1 SV=3"	"2"	"1"	"2"	"1"	"423"	"48.6"	"7.30"	"340.02"	"2.70"	"1"	"1"	"cell organization and biogenesis;transport"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00928"	"8907"	"ENSG00000072958"	"AP1M1"	"hsa:8907; Q4TTY5; Q9BXS5"	"MHC class II antigen presentation; Neutrophil degranulation; Lysosome Vesicle Biogenesis; Golgi Associated Vesicle Biogenesis; Nef mediated downregulation of MHC class I complex cell surface expression"	""	"5"	"0"	"40.5"	"46.4"	"181.6"	"44.5"	"41.2"	"34.3"	"157.7"	"20.7"	"28.8"	"25.0"	"34.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15235"	"28S ribosomal protein S12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS12 PE=1 SV=1"	"8"	"1"	"2"	"1"	"138"	"15.2"	"10.29"	"267.64"	"2.70"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00164"	"6183"	"ENSG00000128626; ENSG00000283018"	"MRPS12"	"hsa:6183; O15235; Q53X98"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"110.8"	"115.0"	"311.8"	"122.1"	"105.6"	"95.1"	"241.0"	"37.4"	"55.1"	"45.9"	"47.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NPA8"	"Transcription and mRNA export factor ENY2 OS=Homo sapiens OX=9606 GN=ENY2 PE=1 SV=1"	"9"	"1"	"2"	"1"	"101"	"11.5"	"9.33"	"382.37"	"2.70"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf10163"	"56943"	"ENSG00000120533"	"ENY2"	"B2RE52; G3V117; hsa:56943; Q9NPA8"	"HATs acetylate histones"	""	"1"	"0"	"102.1"	"91.2"	"298.7"	"96.6"	"103.8"	"78.7"	"343.0"	"60.8"	"88.5"	"71.2"	"105.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z4G1"	"COMM domain-containing protein 6 OS=Homo sapiens OX=9606 GN=COMMD6 PE=1 SV=1"	"15"	"1"	"2"	"1"	"85"	"9.6"	"6.00"	"357.58"	"2.70"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf07258"	"170622"	"ENSG00000188243"	"COMMD6"	"A6NF28; B7ZLN0; hsa:170622; Q5TBK4; Q7Z4G1"	"Neddylation"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WYA6"	"Beta-catenin-like protein 1 OS=Homo sapiens OX=9606 GN=CTNNBL1 PE=1 SV=1"	"1"	"1"	"2"	"1"	"563"	"65.1"	"5.05"	"284.23"	"2.69"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf08216"	"56259"	"ENSG00000132792"	"CTNNBL1"	"B4DE16; hsa:56259; Q0VAL9; Q0VAM0; Q53HI8; Q5JWZ2; Q5JWZ3; Q5JWZ7; Q5JWZ8; Q8N454; Q8NCL2; Q8TBD6; Q8WYA6; Q96KD2; Q9H7A5; Q9NQF9; Q9NTX0; Q9Y3M7"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"40.1"	"51.8"	"216.7"	"43.4"	"30.4"	"32.5"	"144.6"	"20.5"	"25.2"	"38.3"	"46.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96DY2"	"Dynein regulatory complex protein 10 OS=Homo sapiens OX=9606 GN=IQCD PE=1 SV=2"	"2"	"1"	"2"	"1"	"449"	"52.3"	"9.25"	"308.39"	"2.69"	"1"	"1"	""	"cytoskeleton;other cell component"	""	"Pf00612"	"115811"	"ENSG00000166578"	"IQCD"	"hsa:115811; Q6ZSU0; Q96DY2"	""	""	"0"	"0"	"61.0"	"91.8"	"421.2"	"88.2"	"67.7"	"77.3"	"496.6"	"45.9"	"80.9"	"65.3"	"65.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NI27"	"THO complex subunit 2 OS=Homo sapiens OX=9606 GN=THOC2 PE=1 SV=2"	"1"	"1"	"1"	"1"	"1593"	"182.7"	"8.44"	""	"2.69"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf11262, Pf11732, Pf16134"	"57187"	"ENSG00000125676"	"THOC2"	"A6NM50; hsa:57187; Q5JZ12; Q6IN92; Q8NI27; Q9H8I6"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	""	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9BX10"	"GTP-binding protein 2 OS=Homo sapiens OX=9606 GN=GTPBP2 PE=1 SV=1"	"3"	"2"	"3"	"2"	"602"	"65.7"	"8.05"	"524.06"	"2.69"	"2"	"1"	"protein metabolism;other metabolic processes"	"non-structural extracellular;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009"	"54676"	"ENSG00000172432"	"GTPBP2"	"hsa:54676; Q5T7E8; Q8ND84; Q8TAH7; Q8WUA5; Q9BX10; Q9HCS9; Q9NRU4; Q9NX60"	"Platelet degranulation"	"Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway"	"2"	"0"	"20.2"	"16.7"	"74.7"	"20.3"	"13.0"	"19.3"	"90.7"	"8.6"	"15.5"	"11.1"	"8.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P1N0"	"Coiled-coil and C2 domain-containing protein 1A OS=Homo sapiens OX=9606 GN=CC2D1A PE=1 SV=1"	"2"	"1"	"2"	"1"	"951"	"104.0"	"8.09"	"298.89"	"2.69"	"1"	"1"	"RNA metabolism OR transcription;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00168"	"54862"	"ENSG00000132024; ENSG00000288293"	"CC2D1A"	"hsa:54862; Q6P1N0; Q7Z435; Q86XV0; Q8NF89; Q9H603; Q9NXI1"	""	"Sudden infant death syndrome (SIDS) susceptibility pathways"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BRD0"	"BUD13 homolog OS=Homo sapiens OX=9606 GN=BUD13 PE=1 SV=1"	"2"	"1"	"2"	"1"	"619"	"70.5"	"9.86"	"314.61"	"2.68"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf09736"	"84811"	"ENSG00000137656"	"BUD13"	"A8K0S0; hsa:84811; Q96LS7; Q9BRD0"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"8.3"	"12.3"	"26.7"	"13.2"	"12.9"	"8.3"	"34.1"	"13.5"	"13.4"	"9.6"	"19.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96HJ9"	"Protein FMC1 homolog OS=Homo sapiens OX=9606 GN=FMC1 PE=1 SV=2"	"11"	"1"	"2"	"1"	"113"	"12.7"	"10.07"	"232.66"	"2.68"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"mitochondrion"	""	""	"100996928; 154791"	"ENSG00000164898"	"FMC1"	"B7Z4Q3; hsa:100996928; hsa:154791; Q75M90; Q96HJ9; Q9P0B3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NWX6"	"Probable tRNA(His) guanylyltransferase OS=Homo sapiens OX=9606 GN=THG1L PE=1 SV=2"	"4"	"1"	"2"	"1"	"298"	"34.8"	"8.00"	"286.04"	"2.68"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response"	"other membranes;cytosol;mitochondrion;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf04446, Pf14413"	"54974"	"ENSG00000113272"	"THG1L"	"D3DQJ5; hsa:54974; Q53G12; Q7L5R3; Q9H0S2; Q9NWX6"	"tRNA modification in the nucleus and cytosol"	""	"1"	"0"	"15.0"	"16.6"	"37.4"	"16.4"	"12.7"	"10.6"	"51.2"	"8.7"	"11.7"	"6.7"	"8.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P56524"	"Histone deacetylase 4 OS=Homo sapiens OX=9606 GN=HDAC4 PE=1 SV=3"	"1"	"1"	"2"	"1"	"1084"	"119.0"	"6.96"	"238.08"	"2.68"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00850, Pf12203"	"9759"	"ENSG00000068024"	"HDAC4"	"E9PGB9; F5GX36; hsa:9759; P56524; Q86YH7; Q9UND6"	"SUMOylation of chromatin organization proteins; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; SUMOylation of intracellular receptors; NOTCH1 Intracellular Domain Regulates Transcription; Notch-HLH transcription pathway; RUNX3 regulates p14-ARF; RUNX2 regulates chondrocyte maturation"	"MicroRNAs in cardiomyocyte hypertrophy; Genes targeted by miRNAs in adipocytes; Neural crest differentiation; Cardiac hypertrophic response; Initiation of transcription and translation elongation at the HIV-1 LTR; ATM signaling in development and disease ; VEGFA-VEGFR2 signaling; Ethanol effects on histone modifications; Endochondral ossification; Endochondral ossification with skeletal dysplasias; CAMKK2 pathway; 2q37 copy number variation syndrome"	"20"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NRN7"	"L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase OS=Homo sapiens OX=9606 GN=AASDHPPT PE=1 SV=2"	"5"	"1"	"2"	"1"	"309"	"35.8"	"6.80"	"293.81"	"2.68"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol"	"other molecular function"	"Pf01648"	"60496"	"ENSG00000149313"	"AASDHPPT"	"B2R6D1; B4DDW7; hsa:60496; Q9C068; Q9NRN7; Q9P0Q3; Q9UG80; Q9Y389"	"Vitamin B5 (pantothenate) metabolism"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NPB8"	"Glycerophosphocholine phosphodiesterase GPCPD1 OS=Homo sapiens OX=9606 GN=GPCPD1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"672"	"76.0"	"5.53"	"277.20"	"2.67"	"1"	"1"	"other metabolic processes;other biological processes"	"cytosol"	"other molecular function"	"Pf00686, Pf03009"	"56261"	"ENSG00000125772"	"GPCPD1"	"D3DW06; hsa:56261; Q9BQL8; Q9NPB8; Q9NUX0"	"Hydrolysis of LPC; Hydrolysis of LPE"	""	"2"	"0"	"5.2"	"8.4"	"18.4"	"5.2"	"4.1"	"3.6"	"23.6"	"4.5"	"5.4"	"8.2"	"27.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14727"	"Apoptotic protease-activating factor 1 OS=Homo sapiens OX=9606 GN=APAF1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1248"	"141.7"	"6.40"	"303.71"	"2.67"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00400, Pf00619, Pf00931, Pf17908"	"317"	"ENSG00000120868"	"APAF1"	"B2RMX8; hsa:317; O14727; O43297; Q7Z438; Q9BXZ6; Q9UBZ5; Q9UGN8; Q9UGN9; Q9UGP0; Q9UJ58; Q9UJ59; Q9UJ60; Q9UJ61; Q9UJ62; Q9UJ63; Q9UJ64; Q9UJ65; Q9UJ66; Q9UJ67; Q9UNC9"	"Neutrophil degranulation; Transcriptional Regulation by E2F6; Activation of caspases through apoptosome-mediated cleavage; SMAC (DIABLO) binds to IAPs ; SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes ; TP53 Regulates Transcription of Caspase Activators and Caspases; Regulation of the apoptosome activity"	"miRNA regulation of DNA damage response; Alzheimer's disease and miRNA effects; TNF-alpha signaling pathway; Parkinson's disease pathway; Amyotrophic lateral sclerosis (ALS); Nanomaterial induced apoptosis; Apoptosis; Fas ligand pathway and stress induction of heat shock proteins; Apoptosis modulation by HSP70; Oxidative damage response; miRNA regulation of p53 pathway in prostate cancer; Measles virus infection; Small cell lung cancer; Hepatitis B infection; Regucalcin in proximal tubule epithelial kidney cells; Host-pathogen interaction of human coronaviruses - apoptosis; p53 transcriptional gene network; Complement system in neuronal development and plasticity; Alzheimer's disease; CKAP4 signaling pathway map; DNA damage response"	"29"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96RT1"	"Erbin OS=Homo sapiens OX=9606 GN=ERBIN PE=1 SV=2"	"1"	"1"	"2"	"1"	"1412"	"158.2"	"5.50"	"280.73"	"2.67"	"1"	"1"	"cell adhesion;cell organization and biogenesis;transport;signal transduction;other biological processes"	"extracellular matrix;plasma membrane;other membranes;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity"	"Pf00595, Pf13855"	"55914"	"ENSG00000112851"	"ERBIN"	"A0AVR1; B4E3F1; B7ZLV9; E7EQW9; E9PCR8; hsa:55914; Q1RMD0; Q86W38; Q96RT1; Q9NR18; Q9NW48; Q9ULJ5"	"Downregulation of ERBB2 signaling; Signaling by ERBB2 KD Mutants; Signaling by ERBB2 TMD/JMD mutants; Signaling by ERBB2 ECD mutants; Constitutive Signaling by Overexpressed ERBB2; Drug-mediated inhibition of ERBB2 signaling; Resistance of ERBB2 KD mutants to trastuzumab; Resistance of ERBB2 KD mutants to sapitinib; Resistance of ERBB2 KD mutants to tesevatinib; Resistance of ERBB2 KD mutants to neratinib; Resistance of ERBB2 KD mutants to osimertinib; Resistance of ERBB2 KD mutants to afatinib; Resistance of ERBB2 KD mutants to AEE788; Resistance of ERBB2 KD mutants to lapatinib; Drug resistance in ERBB2 TMD/JMD mutants; RHOG GTPase cycle; RHOC GTPase cycle; RHOA GTPase cycle; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOB GTPase cycle"	"Nucleotide-binding oligomerization domain (NOD) pathway; Nod-like receptor (NLR) signaling pathway; Pathways affected in adenoid cystic carcinoma"	"26"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"O95801"	"Tetratricopeptide repeat protein 4 OS=Homo sapiens OX=9606 GN=TTC4 PE=1 SV=3"	"3"	"1"	"2"	"1"	"387"	"44.7"	"5.60"	"314.65"	"2.67"	"1"	"1"	"stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf18972"	"7268"	"ENSG00000243725"	"TTC4"	"hsa:7268; O95801; Q53Y95; Q5TA96; Q9H3I2"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKM9"	"RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1"	"4"	"1"	"2"	"1"	"306"	"32.4"	"9.17"	"275.29"	"2.67"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00076"	"22913"	"ENSG00000125970"	"RALY"	"hsa:22913; Q14621; Q2M365; Q5QPL8; Q9BQX6; Q9UJE3; Q9UKM9"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94760"	"N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 OS=Homo sapiens OX=9606 GN=DDAH1 PE=1 SV=3"	"3"	"1"	"2"	"1"	"285"	"31.1"	"5.81"	"337.45"	"2.67"	"1"	"1"	"other metabolic processes;signal transduction;other biological processes"	"cytosol"	"other molecular function"	"Pf02274"	"23576"	"ENSG00000153904"	"DDAH1"	"hsa:23576; O94760; Q5HYC8; Q86XK5"	"eNOS activation"	"Mesodermal commitment pathway; Nitric oxide metabolism in cystic fibrosis"	"3"	"0"	"90.4"	"112.6"	"476.1"	"101.6"	"74.4"	"59.9"	"616.1"	"47.7"	"66.4"	"52.6"	"52.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H5Y7"	"SLIT and NTRK-like protein 6 OS=Homo sapiens OX=9606 GN=SLITRK6 PE=2 SV=3"	"2"	"1"	"1"	"1"	"841"	"95.0"	"6.52"	""	"2.66"	""	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;other cell component"	""	"Pf13855"	"84189"	"ENSG00000184564"	"SLITRK6"	"A8K9S8; hsa:84189; Q495Q0; Q6AW93; Q9H5Y7; Q9HAA8; Q9NT60"	"Receptor-type tyrosine-protein phosphatases"	""	"1"	"0"	"117.2"	"88.4"	"360.3"	"87.1"	"77.5"	"65.0"	"328.4"	"27.4"	"59.0"	"57.9"	"44.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00217"	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS8 PE=1 SV=1"	"4"	"1"	"2"	"1"	"210"	"23.7"	"6.34"	"327.98"	"2.66"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;stress response;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf12838"	"4728"	"ENSG00000110717"	"NDUFS8"	"B2RB86; hsa:4728; O00217; Q0VDA8"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"5"	"0"	"49.5"	"46.7"	"258.3"	"43.4"	"29.7"	"24.9"	"234.9"	"17.1"	"15.6"	"22.0"	"21.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96FK6"	"WD repeat-containing protein 89 OS=Homo sapiens OX=9606 GN=WDR89 PE=2 SV=1"	"3"	"1"	"2"	"1"	"387"	"43.2"	"6.13"	"337.46"	"2.66"	"1"	"1"	"developmental processes"	""	""	"Pf00400"	"112840"	"ENSG00000140006"	"WDR89"	"hsa:112840; Q96FK6"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"P20290"	"Transcription factor BTF3 OS=Homo sapiens OX=9606 GN=BTF3 PE=1 SV=1"	"4"	"1"	"1"	"1"	"206"	"22.2"	"9.38"	""	"2.66"	""	"1"	"transport;developmental processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	""	"Pf01849"	"689"	"ENSG00000145741"	"BTF3"	"A8K510; hsa:689; P20290; Q13893; Q76M56"	""	"Orexin receptor pathway"	"1"	"0"	"91.2"	"91.4"	"332.4"	"106.7"	"122.4"	"92.5"	"350.8"	"49.8"	"78.7"	"81.1"	"59.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H7D7"	"WD repeat-containing protein 26 OS=Homo sapiens OX=9606 GN=WDR26 PE=1 SV=3"	"2"	"1"	"1"	"1"	"661"	"72.1"	"6.16"	""	"2.66"	""	"1"	"protein metabolism;other metabolic processes"	"cytosol;mitochondrion;nucleus;other cell component"	""	"Pf00400, Pf17814"	"80232"	"ENSG00000162923"	"WDR26"	"A0MNN3; hsa:80232; Q4G100; Q59EC4; Q5GLZ9; Q86UY4; Q9H3C2; Q9H7D7"	""	"Ciliary landscape"	"1"	"0"	"6.6"	"6.7"	"30.6"	"5.4"	"9.1"	"7.0"	"33.2"	"3.0"	"6.6"	"3.0"	"5.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NVQ4"	"Fas apoptotic inhibitory molecule 1 OS=Homo sapiens OX=9606 GN=FAIM PE=1 SV=1"	"7"	"1"	"2"	"1"	"179"	"20.2"	"5.83"	"254.23"	"2.65"	"1"	"1"	"signal transduction;other biological processes"	"other cell component"	""	"Pf06905"	"55179"	"ENSG00000158234"	"FAIM"	"hsa:55179; Q6IAN2; Q9NVQ4"	""	"Neurogenesis regulation in the olfactory epithelium"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NQP4"	"Prefoldin subunit 4 OS=Homo sapiens OX=9606 GN=PFDN4 PE=1 SV=1"	"8"	"1"	"2"	"1"	"134"	"15.3"	"4.53"	"522.66"	"2.65"	"1"	"1"	"other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01920"	"5203"	"ENSG00000101132"	"PFDN4"	"hsa:5203; Q5TD11; Q92779; Q9NQP4"	"Prefoldin mediated transfer of substrate  to CCT/TriC"	"Cellular proteostasis"	"2"	"0"	"54.7"	"83.0"	"607.3"	"98.3"	"75.4"	"60.2"	"939.4"	"55.4"	"94.8"	"48.5"	"41.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61970"	"Nuclear transport factor 2 OS=Homo sapiens OX=9606 GN=NUTF2 PE=1 SV=1"	"11"	"2"	"3"	"1"	"127"	"14.5"	"5.38"	"537.40"	"2.65"	"2"	"1"	"transport;other biological processes"	"other membranes;cytosol;nucleus"	"other molecular function"	"Pf02136"	"10204"	"ENSG00000102898"	"NUTF2"	"B2R4G7; hsa:10204; P13662; P61970; Q6IB67"	""	""	"0"	"0"	"73.3"	"97.2"	"508.6"	"83.5"	"82.4"	"54.1"	"749.2"	"66.1"	"63.0"	"50.5"	"50.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96PU8"	"Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1"	"5"	"2"	"3"	"2"	"341"	"37.6"	"8.56"	"553.23"	"2.64"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf16544, Pf16551"	"9444"	"ENSG00000112531"	"QKI"	"hsa:9444; Q2I375; Q5MJQ1; Q969L9; Q96EJ3; Q96KA3; Q96PU6; Q96PU7; Q96PU8; Q9P0X6; Q9P0X7; Q9P0X8; Q9P0X9; Q9P0Y0; Q9P0Y1"	"Signaling by BRAF and RAF1 fusions"	"VEGFA-VEGFR2 signaling; Exercise-induced circadian regulation"	"3"	"0"	"171.6"	"196.0"	"606.2"	"167.8"	"153.8"	"114.2"	"786.0"	"123.8"	"173.4"	"143.6"	"153.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UHG3"	"Prenylcysteine oxidase 1 OS=Homo sapiens OX=9606 GN=PCYOX1 PE=1 SV=3"	"2"	"1"	"2"	"1"	"505"	"56.6"	"6.18"	"272.39"	"2.64"	"1"	"1"	"protein metabolism;other metabolic processes;transport"	"non-structural extracellular;plasma membrane;other membranes;other cytoplasmic organelle"	"other molecular function"	"Pf07156, Pf13450"	"51449"	"ENSG00000116005"	"PCYOX1"	"B2RB14; B7Z9P8; hsa:51449; O94982; Q8N4N5; Q96QM8; Q9UHG3"	""	""	"0"	"0"	"21.5"	"17.2"	"70.0"	"12.5"	"8.6"	"7.2"	"45.6"	"1.6"	"3.6"	"6.4"	"4.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49458"	"Signal recognition particle 9 kDa protein OS=Homo sapiens OX=9606 GN=SRP9 PE=1 SV=2"	"13"	"1"	"2"	"1"	"86"	"10.1"	"7.97"	"292.23"	"2.64"	"1"	"1"	"transport;other biological processes"	"other membranes;cytosol;ER/Golgi;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf05486"	"6726"	"ENSG00000143742"	"SRP9"	"A8K0N0; hsa:6726; P49458; Q6NVX0; Q8WTW0"	"SRP-dependent cotranslational protein targeting to membrane"	""	"1"	"0"	"56.0"	"52.6"	"225.1"	"40.4"	"37.8"	"27.7"	"115.1"	"15.3"	"28.0"	"25.4"	"39.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NVA1"	"Ubiquinol-cytochrome-c reductase complex assembly factor 1 OS=Homo sapiens OX=9606 GN=UQCC1 PE=1 SV=3"	"4"	"1"	"2"	"1"	"299"	"34.6"	"8.91"	"266.80"	"2.64"	"1"	"1"	"cell organization and biogenesis"	"other membranes;mitochondrion;other cell component"	""	"Pf03981"	"55245"	"ENSG00000101019"	"UQCC1"	"B1AKV5; hsa:55245; Q0VF37; Q5T348; Q5T351; Q5T353; Q86YU3; Q86YU4; Q96H66; Q9H438; Q9H452; Q9H9K8; Q9H9R5; Q9NVA1"	""	"Ciliary landscape; Mitochondrial complex III assembly"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86YR5"	"G-protein-signaling modulator 1 OS=Homo sapiens OX=9606 GN=GPSM1 PE=1 SV=2"	"3"	"1"	"2"	"1"	"675"	"74.5"	"6.54"	"323.26"	"2.63"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02188, Pf13424"	"26086"	"ENSG00000160360"	"GPSM1"	"A9Z1X4; B1B0W3; hsa:26086; Q86SR5; Q86YR5; Q969T1; Q9UFS8"	"G alpha (i) signalling events"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13640"	"Metallothionein-1G OS=Homo sapiens OX=9606 GN=MT1G PE=1 SV=2"	"19"	"1"	"1"	"1"	"62"	"6.1"	"7.96"	""	"2.63"	""	"1"	"other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00131"	"4495"	"ENSG00000125144"	"MT1G"	"hsa:4495; P13640; P80296"	"Metallothioneins bind metals"	"Copper homeostasis; Zinc homeostasis"	"3"	"0"	"20.4"	"20.3"	"82.7"	"19.3"	"19.8"	"16.1"	"88.0"	"11.7"	"22.9"	"15.8"	"11.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NQ48"	"Leucine zipper transcription factor-like protein 1 OS=Homo sapiens OX=9606 GN=LZTFL1 PE=1 SV=1"	"3"	"1"	"2"	"1"	"299"	"34.6"	"5.36"	"239.28"	"2.63"	"1"	"1"	"other biological processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf15294"	"54585"	"ENSG00000163818"	"LZTFL1"	"B3KSI9; B4E0K7; hsa:54585; Q8TC61; Q9NQ48; Q9NQ56"	"BBSome-mediated cargo-targeting to cilium"	"Ciliary landscape; Genes related to primary cilium development (based on CRISPR); Ciliopathies; Bardet-Biedl syndrome"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60231"	"Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1041"	"119.2"	"6.80"	"323.38"	"2.63"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"8449"	"ENSG00000204560; ENSG00000206486; ENSG00000226171; ENSG00000231377; ENSG00000233049; ENSG00000233418; ENSG00000233561"	"DHX16"	"hsa:8449; O60231; O60322; Q5JP45; Q969X7; Q96QC1"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"0"	"10.8"	"12.6"	"50.0"	"11.9"	"8.5"	"12.6"	"43.6"	"6.4"	"11.4"	"8.7"	"7.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NU22"	"Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2"	"0"	"2"	"3"	"2"	"5596"	"632.4"	"5.68"	"594.11"	"2.63"	"2"	"1"	"cell organization and biogenesis;transport"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf07728, Pf17865, Pf17867"	"23195"	"ENSG00000112159; ENSG00000288121"	"MDN1"	"hsa:23195; O15019; Q5T794; Q9NU22"	""	""	"0"	"0"	"57.8"	"70.6"	"258.5"	"58.1"	"46.0"	"48.3"	"231.4"	"26.7"	"34.5"	"24.9"	"31.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H410"	"Kinetochore-associated protein DSN1 homolog OS=Homo sapiens OX=9606 GN=DSN1 PE=1 SV=2"	"4"	"1"	"2"	"1"	"356"	"40.0"	"7.05"	"288.87"	"2.63"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cytoplasmic organelle;other cell component"	""	"Pf08202"	"79980"	"ENSG00000149636"	"DSN1"	"B4DWT2; E1P5U9; hsa:79980; Q5JW55; Q5JW56; Q9H410; Q9H8P4"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Neutrophil degranulation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	""	"7"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"O75494"	"Serine/arginine-rich splicing factor 10 OS=Homo sapiens OX=9606 GN=SRSF10 PE=1 SV=1"	"5"	"1"	"1"	"1"	"262"	"31.3"	"11.27"	""	"2.62"	""	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"10772"	"ENSG00000188529"	"SRSF10"	"A6NFM6; A6NI42; A6NIU7; B4DJP9; hsa:10772; O60572; O75494; Q5JRH9; Q5JRI0; Q5JRI2; Q5JRI3; Q5JRI4; Q96G09; Q96P17"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"mRNA processing"	"3"	"0"	"17.5"	"13.5"	"64.5"	"11.7"	"15.2"	"8.9"	"65.3"	"5.0"	"9.1"	"4.7"	"2.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UJU3"	"Zinc finger protein 112 OS=Homo sapiens OX=9606 GN=ZNF112 PE=1 SV=2"	"1"	"1"	"1"	"1"	"913"	"105.8"	"8.27"	""	"2.62"	""	"1"	"RNA metabolism OR transcription"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00096, Pf01352"	"7771"	"ENSG00000062370"	"ZNF112"	"A4FU53; hsa:7771; Q9HCA7; Q9UJU3"	"Generic Transcription Pathway"	""	"1"	"0"	"458.3"	"432.9"	"970.6"	"320.5"	"330.5"	"295.2"	"845.5"	"104.1"	"169.3"	"133.4"	"105.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P00846"	"ATP synthase subunit a OS=Homo sapiens OX=9606 GN=MT-ATP6 PE=1 SV=1"	"4"	"1"	"2"	"1"	"226"	"24.8"	"10.10"	"269.14"	"2.62"	"1"	"1"	"other metabolic processes;stress response;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf00119"	"4508"	"ENSG00000198899"	"MT-ATP6"	"hsa:4508; P00846; Q34772; Q5S8W5; Q5S9E7; Q5S9I6; Q5SA31; Q6RPB7; Q6VHC0; Q6VHE0; Q6WQF4; Q7YCC1; Q7YCF8; Q7YCG1; Q85KU8; Q85KX1; Q85L05; Q8HNQ4; Q8HNQ8; Q8WCX6; Q9B2U5; Q9B2Z2"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"Electron transport chain: OXPHOS system in mitochondria; 7q11.23 copy number variation syndrome; Oxidative phosphorylation"	"5"	"0"	"50.7"	"61.1"	"238.1"	"44.6"	"33.4"	"27.6"	"116.9"	"10.1"	"20.7"	"13.4"	"15.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P48449"	"Lanosterol synthase OS=Homo sapiens OX=9606 GN=LSS PE=1 SV=1"	"1"	"1"	"2"	"1"	"732"	"83.3"	"6.61"	"340.82"	"2.62"	"1"	"1"	"other metabolic processes;other biological processes"	"other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf00432"	"4047"	"ENSG00000160285"	"LSS"	"B4DJZ9; D3DSN0; E9PEI9; G5E9Q9; hsa:4047; P48449; Q8IYL6; Q9UEZ1"	"Activation of gene expression by SREBF (SREBP); Cholesterol biosynthesis"	"Cholesterol biosynthesis pathway; Sterol regulatory element-binding proteins (SREBP) signaling; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Cholesterol synthesis disorders; Cholesterol metabolism; Enterocyte cholesterol metabolism"	"8"	"0"	"20.4"	"21.6"	"117.7"	"25.6"	"21.6"	"13.5"	"103.6"	"8.4"	"6.0"	"8.5"	"6.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TDX7"	"Serine/threonine-protein kinase Nek7 OS=Homo sapiens OX=9606 GN=NEK7 PE=1 SV=1"	"3"	"1"	"2"	"1"	"302"	"34.5"	"8.25"	"251.67"	"2.62"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"140609"	"ENSG00000151414"	"NEK7"	"A6NGT8; hsa:140609; Q8TDX7"	"EML4 and NUDC in mitotic spindle formation; Nuclear Pore Complex (NPC) Disassembly; Activation of NIMA Kinases NEK9, NEK6, NEK7"	"Ciliary landscape"	"4"	"0"	"3.6"	"3.1"	"12.8"	"4.2"	"2.4"	"2.1"	"11.5"	"3.7"	"11.2"	"31.7"	"51.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43237"	"Cytoplasmic dynein 1 light intermediate chain 2 OS=Homo sapiens OX=9606 GN=DYNC1LI2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"492"	"54.1"	"6.38"	"263.20"	"2.62"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf05783"	"1783"	"ENSG00000135720"	"DYNC1LI2"	"A8K6V1; B4DZP4; hsa:1783; O43237; Q8TAT3"	"Separation of Sister Chromatids; COPI-mediated anterograde transport; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; RHO GTPases Activate Formins; COPI-independent Golgi-to-ER retrograde traffic; HCMV Early Events; Aggrephagy; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"Intraflagellar transport proteins binding to dynein"	"13"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12849"	"G-rich sequence factor 1 OS=Homo sapiens OX=9606 GN=GRSF1 PE=1 SV=3"	"4"	"1"	"1"	"1"	"480"	"53.1"	"6.19"	""	"2.62"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"2926"	"ENSG00000132463"	"GRSF1"	"B3KPW0; hsa:2926; Q12849; Q4W5S5; Q6ZST3; Q8IWD6; Q8NBD2"	"Viral mRNA Translation"	"VEGFA-VEGFR2 signaling"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q13823"	"Nucleolar GTP-binding protein 2 OS=Homo sapiens OX=9606 GN=GNL2 PE=1 SV=1"	"2"	"1"	"1"	"1"	"731"	"83.6"	"9.25"	""	"2.61"	""	"1"	"other biological processes"	"nucleus"	"other molecular function"	"Pf01926, Pf08153"	"29889"	"ENSG00000134697"	"GNL2"	"hsa:29889; Q13823; Q9BWN7"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00483"	"Cytochrome c oxidase subunit NDUFA4 OS=Homo sapiens OX=9606 GN=NDUFA4 PE=1 SV=1"	"10"	"1"	"2"	"1"	"81"	"9.4"	"9.38"	"295.22"	"2.61"	"1"	"1"	"other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf06522"	"4697"	"ENSG00000189043"	"NDUFA4"	"A4D109; hsa:4697; O00483; Q6FHN5"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex IV assembly; Oxidative phosphorylation"	"7"	"0"	"130.1"	"116.5"	"462.6"	"113.5"	"83.1"	"73.1"	"456.9"	"44.5"	"75.7"	"54.1"	"47.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25940"	"Collagen alpha-3(V) chain OS=Homo sapiens OX=9606 GN=COL5A3 PE=1 SV=3"	"1"	"1"	"1"	"1"	"1745"	"172.0"	"6.87"	""	"2.60"	""	"1"	"cell adhesion;cell organization and biogenesis;other biological processes"	"non-structural extracellular;extracellular matrix;ER/Golgi"	"extracellular structural activity;other molecular function"	"Pf01391, Pf01410"	"50509"	"ENSG00000080573"	"COL5A3"	"hsa:50509; P25940; Q9NZQ6"	"Collagen degradation; Signaling by PDGF; Assembly of collagen fibrils and other multimeric structures; Integrin cell surface interactions; ECM proteoglycans; NCAM1 interactions; Collagen chain trimerization; Syndecan interactions; MET activates PTK2 signaling"	"miRNA targets in ECM and membrane receptors; Focal adhesion; Focal adhesion: PI3K-Akt-mTOR-signaling pathway"	"15"	"0"	"81.8"	"85.9"	"256.1"	"105.2"	"100.5"	"83.7"	"321.1"	"42.3"	"83.3"	"70.0"	"68.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NZW5"	"MAGUK p55 subfamily member 6 OS=Homo sapiens OX=9606 GN=MPP6 PE=1 SV=2"	"2"	"1"	"2"	"1"	"540"	"61.1"	"6.18"	"290.80"	"2.60"	"1"	"1"	"cell organization and biogenesis"	"plasma membrane;other membranes;other cell component"	""	"Pf00595, Pf00625, Pf02828, Pf07653"	"51678"	"ENSG00000105926"	"PALS2"	"A4D157; hsa:51678; Q9H0E1; Q9NZW5"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"P56134"	"ATP synthase subunit f, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5MF PE=1 SV=3"	"12"	"1"	"1"	"1"	"94"	"10.9"	"9.67"	""	"2.60"	""	"1"	"other metabolic processes;transport"	"other membranes;mitochondrion;nucleus"	""	"Pf10206"	"9551"	"ENSG00000241468"	"ATP5MF"	"C9J8H9; F8W7V3; hsa:9551; O76079; P56134; Q6IBB3; Q96L83; Q9BTI8"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"Electron transport chain: OXPHOS system in mitochondria; Oxidative phosphorylation"	"4"	"0"	"29.3"	"36.9"	"116.5"	"39.0"	"36.6"	"19.8"	"105.8"	"17.0"	"27.5"	"16.7"	"19.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00291"	"Huntingtin-interacting protein 1 OS=Homo sapiens OX=9606 GN=HIP1 PE=1 SV=5"	"1"	"1"	"1"	"1"	"1037"	"116.1"	"5.30"	""	"2.60"	""	"1"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf01608, Pf07651, Pf16515"	"3092"	"ENSG00000127946"	"HIP1"	"B4E3I7; E7ES17; hsa:3092; O00291; O00328; Q2TB58; Q8TDL4; V5LU97"	"Clathrin-mediated endocytosis; ALK mutants bind TKIs; Signaling by ALK fusions and activated point mutants"	"DYRK1A involvement regarding cell proliferation in brain development"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96KN1"	"Protein LRATD2 OS=Homo sapiens OX=9606 GN=LRATD2 PE=1 SV=1"	"5"	"1"	"2"	"1"	"310"	"34.5"	"5.54"	"251.25"	"2.60"	"1"	"1"	""	"plasma membrane;other membranes;other cell component"	""	"Pf04970"	"157638"	"ENSG00000168672"	"LRATD2"	"hsa:157638; Q96KN1"	""	""	"0"	"0"	"42.2"	"39.7"	"106.9"	"29.3"	"33.7"	"29.5"	"97.3"	"20.8"	"31.2"	"25.2"	"28.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P57678"	"Gem-associated protein 4 OS=Homo sapiens OX=9606 GN=GEMIN4 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1058"	"120.0"	"6.04"	"294.83"	"2.60"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	""	"50628"	"ENSG00000179409"	"GEMIN4"	"hsa:50628; P57678; Q9NZS7; Q9UG32; Q9Y4Q2"	"SARS-CoV-2 modulates host translation machinery; snRNP Assembly"	""	"2"	"0"	"8.6"	"11.6"	"37.2"	"9.5"	"10.2"	"8.6"	"28.6"	"2.0"	"8.8"	"3.0"	"4.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q2TAL5"	"Smoothelin-like protein 2 OS=Homo sapiens OX=9606 GN=SMTNL2 PE=2 SV=1"	"7"	"1"	"1"	"1"	"461"	"50.2"	"8.56"	""	"2.59"	""	"1"	"cell organization and biogenesis"	"cytoskeleton"	""	"Pf00307"	"342527"	"ENSG00000188176"	"SMTNL2"	"hsa:342527; Q2TAL5; Q6ZVK6"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UJX2"	"Cell division cycle protein 23 homolog OS=Homo sapiens OX=9606 GN=CDC23 PE=1 SV=3"	"2"	"1"	"2"	"1"	"597"	"68.8"	"7.02"	"353.19"	"2.59"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf04049"	"8697"	"ENSG00000094880"	"CDC23"	"A8K6E5; B4E3A2; B7WP05; D3DQB7; hsa:8697; O75433; Q53FN2; Q9BS73; Q9UJX2"	"Separation of Sister Chromatids; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Inactivation of APC/C via direct inhibition of the APC/C complex; APC-Cdc20 mediated degradation of Nek2A; Senescence-Associated Secretory Phenotype (SASP); Antigen processing: Ubiquitination & Proteasome degradation; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; CDK-mediated phosphorylation and removal of Cdc6; Autodegradation of Cdh1 by Cdh1:APC/C; Assembly of the pre-replicative complex; APC/C:Cdc20 mediated degradation of Cyclin B; Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase; Regulation of APC/C activators between G1/S and early anaphase; Phosphorylation of the APC/C; Transcriptional Regulation by VENTX; Aberrant regulation of mitotic exit in cancer due to RB1 defects"	"Cell cycle"	"19"	"0"	"41.2"	"52.2"	"157.1"	"37.1"	"38.6"	"32.9"	"131.2"	"11.0"	"19.9"	"16.3"	"22.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5R372"	"Rab GTPase-activating protein 1-like OS=Homo sapiens OX=9606 GN=RABGAP1L PE=1 SV=1"	"1"	"1"	"2"	"1"	"815"	"92.5"	"5.31"	"261.91"	"2.59"	"1"	"1"	"transport;other biological processes"	"ER/Golgi;nucleus;other cytoplasmic organelle"	"enzyme regulator activity;other molecular function"	"Pf00566, Pf12473"	"9910"	"ENSG00000152061"	"RABGAP1L"	"O75059; Q3ZTR8; Q5R369; Q5R372; Q8IVV0; Q8N921; Q8WV78; Q9NSP8; Q9UQ19; Q9UQP5; Q9Y6Y5; Q9Y6Y6"	""	""	"0"	"0"	"12.1"	"13.1"	"54.1"	"15.1"	"15.1"	"12.4"	"49.9"	"10.0"	"8.3"	"9.8"	"5.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35914"	"Hydroxymethylglutaryl-CoA lyase, mitochondrial OS=Homo sapiens OX=9606 GN=HMGCL PE=1 SV=2"	"3"	"1"	"2"	"1"	"325"	"34.3"	"8.54"	"328.93"	"2.59"	"1"	"1"	"cell organization and biogenesis;other metabolic processes"	"cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00682"	"3155"	"ENSG00000117305"	"HMGCL"	"B4DUP4; B7UCC6; D3Y5K7; hsa:3155; P35914; Q6IBC0; Q96FP8"	"Peroxisomal protein import; Synthesis of Ketone Bodies"	"Amino acid metabolism"	"3"	"0"	"5.9"	"12.3"	"44.0"	"8.3"	"9.0"	"8.7"	"47.7"	"7.8"	"7.1"	"6.2"	"7.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07339"	"Cathepsin D OS=Homo sapiens OX=9606 GN=CTSD PE=1 SV=1"	"2"	"1"	"2"	"1"	"412"	"44.5"	"6.54"	"370.49"	"2.59"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"other membranes;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00026, Pf07966"	"1509"	"ENSG00000117984"	"CTSD"	"hsa:1509; P07339; Q6IB57"	"MHC class II antigen presentation; Collagen degradation; Neutrophil degranulation; Estrogen-dependent gene expression; Insulin receptor recycling; Metabolism of Angiotensinogen to Angiotensins"	"Prolactin signaling pathway"	"7"	"0"	"60.2"	"28.8"	"92.6"	"20.6"	"25.6"	"18.3"	"81.1"	"8.5"	"16.4"	"7.8"	"11.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92947"	"Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1"	"4"	"2"	"3"	"2"	"438"	"48.1"	"8.06"	"571.34"	"2.59"	"2"	"1"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00441, Pf02770, Pf02771"	"2639"	"ENSG00000105607"	"GCDH"	"A8K2Z2; hsa:2639; O14719; Q92947"	"Lysine catabolism"	"Fatty acid beta-oxidation; Tryptophan metabolism"	"3"	"0"	"23.9"	"26.4"	"108.3"	"25.1"	"21.4"	"12.9"	"101.0"	"14.8"	"23.3"	"10.1"	"15.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UJU6"	"Drebrin-like protein OS=Homo sapiens OX=9606 GN=DBNL PE=1 SV=1"	"2"	"1"	"1"	"1"	"430"	"48.2"	"5.05"	""	"2.59"	""	"1"	"cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00241, Pf14604"	"28988"	"ENSG00000136279"	"DBNL"	"A4D2I9; B4DDP6; B4DEM2; C9J7P1; hsa:28988; P84070; Q6IAI8; Q96F30; Q96K74; Q9HBN8; Q9NR72; Q9UJU6"	"Neutrophil degranulation; Caspase-mediated cleavage of cytoskeletal proteins; Neurexins and neuroligins"	"T-cell receptor signaling pathway"	"4"	"0"	"38.3"	"36.1"	"94.7"	"31.8"	"37.4"	"30.0"	"111.5"	"22.0"	"37.3"	"31.7"	"23.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9GZS1"	"DNA-directed RNA polymerase I subunit RPA49 OS=Homo sapiens OX=9606 GN=POLR1E PE=1 SV=3"	"5"	"2"	"2"	"2"	"419"	"47.2"	"8.94"	"264.71"	"2.58"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf06870"	"64425"	"ENSG00000137054"	"POLR1E"	"hsa:64425; Q5VZT3; Q8NBA9; Q96L20; Q9GZS1"	"B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Initiation; RNA Polymerase I Transcription Termination"	"Pyrimidine metabolism; Eukaryotic transcription initiation; 2q13 copy number variation syndrome"	"8"	"0"	"10.1"	"9.5"	"35.7"	"10.9"	"6.0"	"8.5"	"36.8"	"9.6"	"35.3"	"36.8"	"45.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NRW7"	"Vacuolar protein sorting-associated protein 45 OS=Homo sapiens OX=9606 GN=VPS45 PE=1 SV=1"	"2"	"1"	"2"	"1"	"570"	"65.0"	"8.24"	"266.61"	"2.58"	"1"	"1"	"transport"	"other membranes;ER/Golgi;other cytoplasmic organelle"	""	"Pf00995"	"11311"	"ENSG00000136631"	"VPS45"	"D3DUZ9; F5H8K1; hsa:11311; Q15715; Q53FR8; Q5T4P6; Q9NRW7; Q9Y4Z6"	"Intra-Golgi traffic; Factors involved in megakaryocyte development and platelet production; SARS-CoV-2 modulates autophagy"	""	"3"	"0"	"10.2"	"9.1"	"44.0"	"10.3"	"9.9"	"3.3"	"28.9"	"4.5"	"4.6"	"6.5"	"4.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5T5C0"	"Syntaxin-binding protein 5 OS=Homo sapiens OX=9606 GN=STXBP5 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1151"	"127.5"	"7.28"	"251.71"	"2.58"	"1"	"1"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00400, Pf08366, Pf08596"	"134957"	"ENSG00000164506"	"STXBP5"	"hsa:134957; Q14DF3; Q5T5C0; Q5T5C1; Q5T5C2; Q8NBG8; Q96NG9"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NRY4"	"Rho GTPase-activating protein 35 OS=Homo sapiens OX=9606 GN=ARHGAP35 PE=1 SV=3"	"1"	"1"	"2"	"1"	"1499"	"170.4"	"6.64"	"242.78"	"2.58"	"1"	"1"	"cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00071, Pf00620, Pf01846, Pf16512, Pf19518"	"2909"	"ENSG00000160007"	"ARHGAP35"	"A7E2A4; hsa:2909; Q14452; Q9C0E1; Q9NRY4"	"RND3 GTPase cycle; RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOJ GTPase cycle; RND2 GTPase cycle; RHOB GTPase cycle; RHOD GTPase cycle; RND1 GTPase cycle; Sema4D mediated inhibition of cell attachment and migration; PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"	"Focal adhesion; Regulation of actin cytoskeleton"	"18"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N3C0"	"Activating signal cointegrator 1 complex subunit 3 OS=Homo sapiens OX=9606 GN=ASCC3 PE=1 SV=3"	"1"	"1"	"2"	"1"	"2202"	"251.3"	"7.09"	"371.41"	"2.58"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271, Pf02889"	"10973"	"ENSG00000112249"	"ASCC3"	"E7EW23; hsa:10973; O43738; Q4G1A0; Q5VTN2; Q8N3C0; Q9H1I9; Q9H5A2; Q9NTR0"	"ALKBH3 mediated reversal of alkylation damage"	"Mesodermal commitment pathway; VEGFA-VEGFR2 signaling"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TCC3"	"39S ribosomal protein L30, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL30 PE=1 SV=1"	"6"	"1"	"2"	"1"	"161"	"18.5"	"9.99"	"276.14"	"2.58"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00327"	"51263"	"ENSG00000185414"	"MRPL30"	"A6NIC6; D3DVI0; D3DVI3; hsa:51263; Q0D2Q7; Q6ZTP4; Q8TCC3; Q96Q69; Q9P0N0"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"20.0"	"18.9"	"42.6"	"22.7"	"18.5"	"14.9"	"61.7"	"9.0"	"15.1"	"11.1"	"8.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NTJ5"	"Phosphatidylinositide phosphatase SAC1 OS=Homo sapiens OX=9606 GN=SACM1L PE=1 SV=2"	"2"	"1"	"2"	"1"	"587"	"66.9"	"7.12"	"321.25"	"2.58"	"1"	"1"	"other metabolic processes"	"other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf02383"	"22908"	"ENSG00000211456"	"SACM1L"	"A8K527; B4DK71; hsa:22908; O94935; Q7LA14; Q7LA22; Q96AX7; Q9NQ46; Q9NQ57; Q9NTJ5"	"Synthesis of PIPs at the Golgi membrane; Synthesis of PIPs at the ER membrane"	""	"2"	"0"	"26.5"	"26.5"	"170.5"	"29.6"	"14.8"	"15.2"	"138.0"	"9.9"	"11.8"	"14.3"	"12.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6NSI4"	"RPA-related protein RADX OS=Homo sapiens OX=9606 GN=RADX PE=1 SV=2"	"1"	"1"	"1"	"1"	"855"	"97.5"	"8.41"	""	"2.57"	""	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf17659"	"55086"	"ENSG00000147231"	"RADX"	"H7BY89; hsa:55086; Q4G0L7; Q5JQS1; Q5JRF9; Q6NSI4; Q6PHY5; Q6PII9; Q6PJU8; Q9H7W5; Q9NWA6"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H936"	"Mitochondrial glutamate carrier 1 OS=Homo sapiens OX=9606 GN=SLC25A22 PE=1 SV=1"	"7"	"1"	"1"	"1"	"323"	"34.4"	"9.29"	""	"2.57"	""	"1"	"other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity"	"Pf00153"	"79751"	"ENSG00000177542"	"SLC25A22"	"A8K366; C9J1H6; E9PJD3; E9PKB2; E9PL68; E9PN26; E9PNQ3; E9PP01; E9PR97; hsa:79751; Q8TBU8; Q9H936"	"Organic anion transporters"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"P12955"	"Xaa-Pro dipeptidase OS=Homo sapiens OX=9606 GN=PEPD PE=1 SV=3"	"2"	"1"	"2"	"1"	"493"	"54.5"	"6.00"	"307.52"	"2.57"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	""	"other molecular function"	"Pf00557, Pf05195"	"5184"	"ENSG00000124299"	"PEPD"	"A8K3Z1; A8K416; A8K696; A8MX47; B4DDB7; B4DGJ1; E9PCE8; hsa:5184; P12955; Q8TBN9; Q9BT75"	""	""	"0"	"0"	"16.8"	"15.2"	"88.6"	"22.5"	"14.9"	"13.1"	"145.7"	"9.1"	"14.9"	"15.1"	"26.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BSJ2"	"Gamma-tubulin complex component 2 OS=Homo sapiens OX=9606 GN=TUBGCP2 PE=1 SV=2"	"1"	"1"	"2"	"1"	"902"	"102.5"	"6.84"	"372.45"	"2.57"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes"	"cytosol;cytoskeleton;nucleus"	"cytoskeletal activity"	"Pf04130, Pf17681"	"10844"	"ENSG00000130640"	"TUBGCP2"	"B4DM18; B7ZKL8; F5H4E0; F5H4L0; hsa:10844; O43632; Q5VWX7; Q9BSJ2"	"Recruitment of NuMA to mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes"	"15q11.2 copy number variation syndrome"	"3"	"0"	"21.7"	"20.7"	"99.0"	"26.6"	"18.5"	"15.0"	"88.8"	"7.9"	"11.1"	"10.7"	"7.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P1J9"	"Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1"	"2"	"1"	"2"	"1"	"531"	"60.5"	"9.61"	"284.47"	"2.57"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf05179, Pf16050"	"79577"	"ENSG00000134371"	"CDC73"	"A6NLZ8; B2RBR2; hsa:79577; Q6P1J9; Q6PK51; Q96A07; Q9H245; Q9H5L7"	"Hedgehog 'on' state; E3 ubiquitin ligases ubiquitinate target proteins; Formation of the beta-catenin:TCF transactivating complex; Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events"	"Endoderm differentiation"	"7"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q96AA3"	"Protein RFT1 homolog OS=Homo sapiens OX=9606 GN=RFT1 PE=1 SV=1"	"2"	"1"	"2"	"1"	"541"	"60.3"	"8.85"	"304.89"	"2.57"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport"	"other membranes;ER/Golgi"	"transporter activity"	"Pf04506"	"91869"	"ENSG00000163933"	"RFT1"	"hsa:91869; Q96AA3; Q96J03"	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein; Defective RFT1 causes CDG-1n"	"N-glycan biosynthesis"	"3"	"0"	"39.3"	"34.7"	"173.2"	"31.6"	"22.1"	"22.7"	"164.9"	"19.4"	"37.1"	"28.1"	"29.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P42771"	"Cyclin-dependent kinase inhibitor 2A OS=Homo sapiens OX=9606 GN=CDKN2A PE=1 SV=2"	"8"	"1"	"2"	"1"	"156"	"16.5"	"5.81"	"252.68"	"2.57"	"1"	"1"	"cell cycle OR cell proliferation;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	""	"1029"	"ENSG00000147889"	"CDKN2A"	"A5X2G7; D3DRK1; G3XAG3; hsa:1029; O95440; P42771; Q15191; Q5VVJ5; Q96B52; Q9NP05"	"Oxidative Stress Induced Senescence; Oncogene Induced Senescence; Cyclin D associated events in G1; Senescence-Associated Secretory Phenotype (SASP); Transcriptional Regulation by VENTX; Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4; Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6; Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4; Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6"	"TP53 network; Cell cycle; Glioblastoma signaling pathways; Apoptosis; Bladder cancer; Vitamin D receptor pathway; Tumor suppressor activity of SMARCB1; Non-small cell lung cancer; Pancreatic adenocarcinoma pathway; G1 to S cell cycle control; Fragile X syndrome; Gastrin signaling pathway; Head and neck squamous cell carcinoma; Melanoma; Pleural mesothelioma; TROP2 regulatory signaling"	"25"	"0"	"183.5"	"112.7"	"263.6"	"105.2"	"90.2"	"78.2"	"231.6"	"58.0"	"73.4"	"58.7"	"71.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96BN2"	"Transcriptional adapter 1 OS=Homo sapiens OX=9606 GN=TADA1 PE=1 SV=1"	"3"	"1"	"1"	"1"	"335"	"37.4"	"7.39"	""	"2.56"	""	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf12767"	"117143"	"ENSG00000152382"	"TADA1"	"A8K4J9; hsa:117143; Q96BN2"	"HATs acetylate histones"	""	"1"	"0"	"57.1"	"74.6"	"471.8"	"70.5"	"62.1"	"48.2"	"550.1"	"51.6"	"53.7"	"40.1"	"56.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22735"	"Protein-glutamine gamma-glutamyltransferase K OS=Homo sapiens OX=9606 GN=TGM1 PE=1 SV=4"	"1"	"1"	"2"	"1"	"817"	"89.7"	"6.04"	"270.55"	"2.56"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol"	"other molecular function"	"Pf00868, Pf00927, Pf01841"	"7051"	"ENSG00000092295; ENSG00000285348"	"TGM1"	"B4DWR7; hsa:7051; P22735; Q197M4"	"Formation of the cornified envelope"	""	"1"	"0"	"94.3"	"35.9"	"26.9"	"9.2"	"7.0"	"8.0"	"17.6"	"5.6"	"5.8"	"4.6"	"6.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2G9"	"Protein strawberry notch homolog 2 OS=Homo sapiens OX=9606 GN=SBNO2 PE=2 SV=3"	"1"	"1"	"1"	"1"	"1366"	"150.2"	"6.52"	""	"2.56"	""	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf13871, Pf13872"	"22904"	"ENSG00000064932; ENSG00000278788"	"SBNO2"	"A8K8P2; B3KWJ1; hsa:22904; O75257; Q3KQX0; Q8TEM0; Q9Y2G9"	""	""	"0"	"0"	"52.6"	"65.0"	"196.2"	"62.5"	"64.4"	"44.8"	"242.3"	"47.6"	"69.5"	"50.6"	"57.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQ67"	"Glutamate-rich WD repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=GRWD1 PE=1 SV=1"	"2"	"1"	"2"	"1"	"446"	"49.4"	"4.92"	"335.80"	"2.56"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400, Pf12265"	"83743"	"ENSG00000105447"	"GRWD1"	"A0MNN5; hsa:83743; Q8TF59; Q9BQ67"	""	""	"0"	"0"	"96.3"	"108.2"	"257.1"	"106.2"	"110.1"	"105.2"	"314.5"	"75.9"	"118.2"	"103.6"	"96.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P78324"	"Tyrosine-protein phosphatase non-receptor type substrate 1 OS=Homo sapiens OX=9606 GN=SIRPA PE=1 SV=2"	"3"	"1"	"2"	"1"	"504"	"54.9"	"6.98"	"368.42"	"2.56"	"1"	"1"	"cell adhesion;stress response;other biological processes"	"plasma membrane;other membranes;other cell component"	"enzyme regulator activity;other molecular function"	"Pf07654, Pf07686"	"140885"	"ENSG00000198053"	"SIRPA"	"A2A2E1; A8K411; B2R6C3; hsa:140885; O00683; O43799; P78324; Q8N517; Q8TAL8; Q9H0Z2; Q9UDX2; Q9UIJ6; Q9Y4U9"	"Neutrophil degranulation; Cell surface interactions at the vascular wall; Signal regulatory protein family interactions"	"Prolactin signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Cardiac progenitor differentiation; Male infertility"	"7"	"0"	"9.6"	"9.9"	"37.5"	"5.3"	"7.6"	"2.8"	"40.2"	"4.7"	"5.4"	"0.0"	"4.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92733"	"Proline-rich protein PRCC OS=Homo sapiens OX=9606 GN=PRCC PE=1 SV=1"	"5"	"3"	"4"	"2"	"491"	"52.4"	"5.10"	"861.93"	"2.56"	"3"	"1"	"cell cycle OR cell proliferation;other biological processes"	"nucleus"	""	"Pf10253"	"5546"	"ENSG00000143294"	"PRCC"	"A8K1F7; hsa:5546; O00665; O00724; Q5SZ06; Q92733"	"mRNA Splicing - Major Pathway"	"Type 2 papillary renal cell carcinoma; IL-18 signaling pathway"	"3"	"1"	"233.9"	"244.2"	"614.7"	"253.5"	"289.2"	"243.8"	"831.6"	"222.9"	"359.5"	"295.6"	"295.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BXB4"	"Oxysterol-binding protein-related protein 11 OS=Homo sapiens OX=9606 GN=OSBPL11 PE=1 SV=2"	"1"	"1"	"2"	"1"	"747"	"83.6"	"7.06"	"313.15"	"2.56"	"1"	"1"	"transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf00169, Pf01237"	"114885"	"ENSG00000144909"	"OSBPL11"	"A8K9I7; hsa:114885; Q9BXB4"	"RHOH GTPase cycle"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q05519"	"Serine/arginine-rich splicing factor 11 OS=Homo sapiens OX=9606 GN=SRSF11 PE=1 SV=1"	"4"	"2"	"3"	"2"	"484"	"53.5"	"10.52"	"654.83"	"2.56"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00076"	"9295"	"ENSG00000116754"	"SRSF11"	"hsa:9295; Q05519; Q5T758; Q8IWE6"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	""	"5"	"0"	"194.0"	"201.3"	"921.0"	"179.9"	"155.7"	"124.9"	"810.1"	"79.1"	"129.0"	"76.2"	"84.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14562"	"ATP-dependent RNA helicase DHX8 OS=Homo sapiens OX=9606 GN=DHX8 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1220"	"139.2"	"8.32"	"237.95"	"2.56"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf00271, Pf00575, Pf04408, Pf07717"	"1659"	"ENSG00000067596"	"DHX8"	"hsa:1659; Q14562"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"0"	"9.2"	"10.8"	"45.0"	"12.9"	"12.9"	"7.3"	"45.7"	"5.3"	"10.3"	"8.4"	"7.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKN8"	"General transcription factor 3C polypeptide 4 OS=Homo sapiens OX=9606 GN=GTF3C4 PE=1 SV=2"	"3"	"2"	"3"	"2"	"822"	"91.9"	"6.65"	"743.42"	"2.55"	"2"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf12657, Pf12660, Pf19336"	"9329"	"ENSG00000125484"	"GTF3C4"	"hsa:9329; Q5VZJ7; Q9UKN8"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter"	""	"3"	"0"	"25.0"	"19.4"	"76.8"	"20.9"	"26.0"	"16.0"	"106.5"	"9.4"	"9.8"	"9.1"	"12.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30307"	"M-phase inducer phosphatase 3 OS=Homo sapiens OX=9606 GN=CDC25C PE=1 SV=2"	"2"	"1"	"2"	"1"	"473"	"53.3"	"6.79"	"331.22"	"2.55"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00581, Pf06617"	"995"	"ENSG00000158402"	"CDC25C"	"D3DQB8; hsa:995; P30307; Q96PL3; Q9H168; Q9H2E8; Q9H2E9; Q9H2F1"	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain; Activation of ATR in response to replication stress; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RHO GTPases activate PKNs; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Cyclin A/B1/B2 associated events during G2/M transition; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models; Polo-like kinase mediated events"	"miRNA regulation of DNA damage response; Cell cycle; ATM signaling pathway; p53 transcriptional gene network; CCL18 signaling pathway; DNA damage response; Monoamine transport"	"15"	"0"	"12.4"	"16.9"	"65.1"	"23.9"	"22.0"	"9.2"	"51.5"	"5.3"	"5.4"	"5.8"	"4.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NRK6"	"ATP-binding cassette sub-family B member 10, mitochondrial OS=Homo sapiens OX=9606 GN=ABCB10 PE=1 SV=2"	"1"	"1"	"2"	"1"	"738"	"79.1"	"9.85"	"302.15"	"2.55"	"1"	"1"	"other metabolic processes;stress response;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00005, Pf00664"	"23456"	"ENSG00000135776"	"ABCB10"	"hsa:23456; Q13040; Q6P1Q8; Q9H3V0; Q9NRK6"	"Mitochondrial ABC transporters"	""	"1"	"0"	"10.1"	"12.8"	"72.2"	"9.4"	"7.7"	"5.4"	"63.1"	"0.0"	"0.3"	"0.0"	"0.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q8NGA1"	"Olfactory receptor 1M1 OS=Homo sapiens OX=9606 GN=OR1M1 PE=2 SV=1"	"2"	"1"	"2"	"1"	"313"	"34.8"	"8.91"	"284.51"	"2.55"	"1"	"1"	"signal transduction;other biological processes"	"plasma membrane;other membranes"	"other molecular function"	"Pf13853"	"125963"	"ENSG00000170929"	"OR1M1"	"B9EHA6; hsa:125963; Q6IFJ3; Q8NGA1; Q96R91"	"Expression and translocation of olfactory receptors"	""	"1"	"0"	"53.6"	"136.3"	"770.9"	"127.5"	"77.6"	"69.1"	"685.1"	"70.6"	"97.7"	"57.5"	"35.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14406"	"Cytochrome c oxidase subunit 7A2, mitochondrial OS=Homo sapiens OX=9606 GN=COX7A2 PE=1 SV=1"	"12"	"1"	"2"	"1"	"83"	"9.4"	"9.76"	"304.14"	"2.54"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf02238"	"1347"	"ENSG00000112695"	"COX7A2"	"B2R5E1; hsa:1347; P14406; Q3MIH5; Q5TF59; Q6FGI2"	""	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex IV assembly"	"3"	"0"	"154.5"	"168.3"	"655.6"	"122.3"	"109.2"	"99.0"	"747.8"	"72.8"	"90.1"	"62.6"	"79.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H9T3"	"Elongator complex protein 3 OS=Homo sapiens OX=9606 GN=ELP3 PE=1 SV=2"	"2"	"1"	"2"	"1"	"547"	"62.2"	"8.88"	"341.19"	"2.54"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00583, Pf04055, Pf16199"	"55140"	"ENSG00000134014"	"ELP3"	"B4DE19; B4DIG1; E2QRI5; hsa:55140; Q53G84; Q6AWB0; Q9BVF7; Q9H9T3; Q9NVZ1"	"HATs acetylate histones"	"Ethanol effects on histone modifications"	"2"	"0"	"40.0"	"46.2"	"102.2"	"44.9"	"36.6"	"37.7"	"98.1"	"15.7"	"24.1"	"24.3"	"23.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q93008"	"Probable ubiquitin carboxyl-terminal hydrolase FAF-X OS=Homo sapiens OX=9606 GN=USP9X PE=1 SV=3"	"1"	"2"	"3"	"2"	"2570"	"292.1"	"5.80"	"537.38"	"2.54"	"2"	"1"	"protein metabolism;other metabolic processes"	""	"other molecular function"	"Pf00443, Pf12030"	"100971796; 465582"	"ENSPPAG00000039671; ENSPTRG00000045541"	"USP9X"	"A0A2I3RAB4; A0A2J8JDU7; A0A2R9BVD0; A0A6D2WW26"	""	""	"0"	"0"	"79.8"	"80.6"	"253.1"	"69.6"	"58.7"	"56.7"	"228.7"	"30.6"	"45.2"	"28.3"	"34.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H0R6"	"Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial OS=Homo sapiens OX=9606 GN=QRSL1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"528"	"57.4"	"5.68"	"274.19"	"2.54"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf01425"	"55278"	"ENSG00000130348"	"QRSL1"	"hsa:55278; Q5VWJ4; Q9H0R6; Q9HA60; Q9NV19"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"O75688"	"Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1"	"2"	"1"	"2"	"1"	"479"	"52.6"	"5.05"	"338.12"	"2.54"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;cytosol;nucleus"	"other molecular function"	"Pf00481, Pf07830"	"5495"	"ENSG00000138032"	"PPM1B"	"hsa:5495; O75688; Q461Q2; Q4J6C1; Q4J6C2; Q658R4; Q96ER6; Q9HAY8"	"ISG15 antiviral mechanism; ALK mutants bind TKIs; Signaling by ALK fusions and activated point mutants"	"MAPK signaling pathway"	"4"	"0"	"30.9"	"38.5"	"65.4"	"32.1"	"45.9"	"35.4"	"77.2"	"17.7"	"27.1"	"20.3"	"16.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BV57"	"1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase OS=Homo sapiens OX=9606 GN=ADI1 PE=1 SV=1"	"4"	"1"	"2"	"1"	"179"	"21.5"	"5.68"	"353.28"	"2.53"	"1"	"1"	"other metabolic processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf03079"	"55256"	"ENSG00000182551"	"ADI1"	"D6W4Y3; hsa:55256; Q53HW3; Q53QD3; Q57YV7; Q68CK2; Q6ZSF7; Q7Z512; Q96P85; Q9BV57; Q9NV57"	"Methionine salvage pathway"	"Methionine de novo and salvage pathway"	"2"	"0"	"50.3"	"62.6"	"188.8"	"50.3"	"58.6"	"52.0"	"224.6"	"48.9"	"48.6"	"36.1"	"31.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12797"	"Aspartyl/asparaginyl beta-hydroxylase OS=Homo sapiens OX=9606 GN=ASPH PE=1 SV=3"	"1"	"1"	"2"	"1"	"758"	"85.8"	"5.01"	"295.50"	"2.53"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi"	"other molecular function"	"Pf05118, Pf05279, Pf13432"	"444"	"ENSG00000198363"	"ASPH"	"A0A0A0MSK8; A6NDF4; A6NHI2; B4DIC9; B4E2K4; B7ZM95; E5RGP5; F5H667; hsa:444; Q12797; Q6NXR7; Q8TB28; Q9H291; Q9H2C4; Q9NRI0; Q9NRI1; Q9Y4J0"	"Stimuli-sensing channels; Ion homeostasis"	""	"2"	"0"	"30.9"	"35.5"	"126.9"	"31.1"	"27.3"	"22.2"	"106.5"	"21.7"	"18.6"	"31.5"	"57.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49642"	"DNA primase small subunit OS=Homo sapiens OX=9606 GN=PRIM1 PE=1 SV=1"	"3"	"1"	"2"	"1"	"420"	"49.9"	"8.21"	"302.58"	"2.53"	"1"	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf01896"	"5557"	"ENSG00000198056"	"PRIM1"	"hsa:5557; P49642"	"Activation of the pre-replicative complex; Removal of the Flap Intermediate; Polymerase switching on the C-strand of the telomere; Polymerase switching; Defective pyroptosis; Inhibition of replication initiation of damaged DNA by RB1/E2F1; Telomere C-strand synthesis initiation; DNA replication initiation"	"Retinoblastoma gene in cancer; Pyrimidine metabolism; G1 to S cell cycle control; DNA replication"	"13"	"0"	"19.7"	"19.5"	"68.8"	"10.2"	"10.6"	"12.6"	"34.8"	"5.6"	"8.2"	"10.2"	"12.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86TJ2"	"Transcriptional adapter 2-beta OS=Homo sapiens OX=9606 GN=TADA2B PE=1 SV=2"	"3"	"1"	"2"	"1"	"420"	"48.4"	"7.83"	"253.30"	"2.53"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00249"	"93624"	"ENSG00000173011"	"TADA2B"	"A0AUJ8; A4QMR7; B3KSN0; B3KU86; hsa:93624; Q6MZG9; Q86TJ2"	"Ub-specific processing proteases; HATs acetylate histones"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q10472"	"Polypeptide N-acetylgalactosaminyltransferase 1 OS=Homo sapiens OX=9606 GN=GALNT1 PE=1 SV=1"	"2"	"1"	"2"	"1"	"559"	"64.2"	"7.72"	"305.98"	"2.52"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf00535, Pf00652"	"2589"	"ENSG00000141429"	"GALNT1"	"hsa:2589; Q10472; Q86TJ7; Q9UM86"	"COPI-independent Golgi-to-ER retrograde traffic; O-linked glycosylation of mucins; Maturation of protein 3a; Maturation of protein 3a"	"Metabolism of sphingolipids in ER and Golgi apparatus"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q05655"	"Protein kinase C delta type OS=Homo sapiens OX=9606 GN=PRKCD PE=1 SV=2"	"2"	"1"	"2"	"1"	"676"	"77.5"	"7.75"	"239.89"	"2.52"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069, Pf00130, Pf00433"	"5580"	"ENSG00000163932"	"PRKCD"	"B0KZ81; B2R834; hsa:5580; Q05655; Q15144; Q86XJ6"	"CLEC7A (Dectin-1) signaling; KEAP1-NFE2L2 pathway; Neutrophil degranulation; Role of phospholipids in phagocytosis; G alpha (z) signalling events; Interferon gamma signaling; SHC1 events in ERBB2 signaling; HuR (ELAVL1) binds and stabilizes mRNA; VEGFR2 mediated cell proliferation; DAG and IP3 signaling; Effects of PIP2 hydrolysis; RHO GTPases Activate NADPH Oxidases; Calmodulin induced events; Apoptotic cleavage of cellular proteins"	"Type II diabetes mellitus; Glioblastoma signaling pathways; B cell receptor signaling pathway; AGE/RAGE pathway; Corticotropin-releasing hormone signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Alpha 6 beta 4 signaling pathway; Myometrial relaxation and contraction pathways; G protein signaling pathways; IL6 signaling pathway; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Wnt signaling pathway and pluripotency; Pancreatic adenocarcinoma pathway; Non-genomic actions of 1,25 dihydroxyvitamin D3; EGF/EGFR signaling pathway; Hippo signaling regulation pathways; Translation inhibitors in chronically activated PDGFRA cells; Gastrin signaling pathway; IL-18 signaling pathway; Osteoblast differentiation and related diseases; Insulin signaling; Kisspeptin/kisspeptin receptor system in the ovary; Galanin receptor pathway; Orexin receptor pathway; CCL18 signaling pathway; Chronic hyperglycemia impairment of neuron function; TROP2 regulatory signaling; Calcium regulation in cardiac cells; Type II interferon signaling; T-cell receptor signaling pathway"	"47"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BW83"	"Intraflagellar transport protein 27 homolog OS=Homo sapiens OX=9606 GN=IFT27 PE=1 SV=1"	"6"	"1"	"2"	"1"	"186"	"20.5"	"5.41"	"301.26"	"2.52"	"1"	"1"	"cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytoskeleton;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00071"	"11020"	"ENSG00000100360"	"IFT27"	"hsa:11020; O60897; Q9BW83"	"Intraflagellar transport"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein; Genes related to primary cilium development (based on CRISPR); Ciliopathies; GDNF/RET signaling axis; Alstrom syndrome; Bardet-Biedl syndrome"	"8"	"0"	"7.3"	"8.0"	"41.2"	"4.3"	"8.9"	"6.8"	"43.7"	"3.4"	"5.5"	"3.7"	"2.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P29590"	"Protein PML OS=Homo sapiens OX=9606 GN=PML PE=1 SV=3"	"1"	"1"	"2"	"1"	"882"	"97.5"	"6.21"	"268.31"	"2.52"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00643, Pf12126"	"5371"	"ENSG00000140464"	"PML"	"E9PBR7; hsa:5371; P29590; P29591; P29592; P29593; Q00755; Q15959; Q59FP9; Q8WUA0; Q96S41; Q9BPW2; Q9BWP7; Q9BZX6; Q9BZX7; Q9BZX8; Q9BZX9; Q9BZY0; Q9BZY2; Q9BZY3"	"HCMV Early Events; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Interferon gamma signaling; Regulation of TP53 Activity through Acetylation; Regulation of PTEN localization; Regulation of RUNX1 Expression and Activity"	"miRNA regulation of DNA damage response; Wnt/beta-catenin signaling pathway in leukemia; p53 transcriptional gene network; DNA damage response"	"11"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5M8"	"Signal recognition particle receptor subunit beta OS=Homo sapiens OX=9606 GN=SRPRB PE=1 SV=3"	"4"	"1"	"2"	"1"	"271"	"29.7"	"9.04"	"284.63"	"2.52"	"1"	"1"	"cell organization and biogenesis;transport"	"other membranes;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf09439"	"58477"	"ENSG00000144867"	"SRPRB"	"hsa:58477; Q6P595; Q8N2D8; Q9Y5M8"	"SRP-dependent cotranslational protein targeting to membrane; XBP1(S) activates chaperone genes"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"P46019"	"Phosphorylase b kinase regulatory subunit alpha, liver isoform OS=Homo sapiens OX=9606 GN=PHKA2 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1235"	"138.3"	"6.44"	"242.25"	"2.52"	"1"	"1"	"protein metabolism;other metabolic processes"	"plasma membrane;other membranes;cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00723, Pf19292"	"5256"	"ENSG00000044446"	"PHKA2"	"A8K1T1; hsa:5256; P46019; Q6LAJ5; Q7Z6W0; Q96CR3; Q9UDA1"	"Glycogen breakdown (glycogenolysis)"	"Type II diabetes mellitus; Glycogen synthesis and degradation"	"3"	"0"	"9.7"	"9.4"	"35.0"	"10.6"	"8.4"	"11.0"	"30.8"	"7.5"	"7.0"	"7.0"	"8.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75419"	"Cell division control protein 45 homolog OS=Homo sapiens OX=9606 GN=CDC45 PE=1 SV=1"	"3"	"1"	"2"	"1"	"566"	"65.5"	"5.53"	"293.21"	"2.52"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;signal transduction"	"cytoskeleton;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf02724"	"8318"	"ENSG00000093009"	"CDC45"	"B4DDB4; B4DDU3; E9PDH7; hsa:8318; O60856; O75419; Q20WK8; Q6UW54; Q9UP68"	"Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA; G1/S-Specific Transcription"	"Cell cycle; Retinoblastoma gene in cancer; G1 to S cell cycle control; 22q11.2 copy number variation syndrome; DNA replication"	"9"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9BTD8"	"RNA-binding protein 42 OS=Homo sapiens OX=9606 GN=RBM42 PE=1 SV=1"	"2"	"1"	"2"	"1"	"480"	"50.4"	"9.63"	"326.56"	"2.52"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"79171"	"ENSG00000126254"	"RBM42"	"hsa:79171; O00320; Q8N5R7; Q9BTD8; Q9BU66"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"10.0"	"16.2"	"49.7"	"10.9"	"13.5"	"6.4"	"61.1"	"5.3"	"9.2"	"6.9"	"11.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11172"	"Uridine 5'-monophosphate synthase OS=Homo sapiens OX=9606 GN=UMPS PE=1 SV=1"	"7"	"3"	"4"	"3"	"480"	"52.2"	"7.24"	"955.50"	"2.52"	"3"	"1"	"other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00156, Pf00215"	"7372"	"ENSG00000114491"	"UMPS"	"B5LY68; B5LY72; hsa:7372; O00758; O00759; O00760; P11172; Q16862; Q9H3Q2; Q9UG49"	"Pyrimidine biosynthesis"	"Fluoropyrimidine activity; Pyrimidine metabolism"	"3"	"0"	"151.2"	"163.8"	"669.4"	"125.2"	"110.5"	"77.3"	"722.5"	"68.0"	"97.0"	"67.9"	"74.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q68E01"	"Integrator complex subunit 3 OS=Homo sapiens OX=9606 GN=INTS3 PE=1 SV=1"	"3"	"1"	"1"	"1"	"1043"	"118.0"	"5.80"	""	"2.51"	""	"1"	"cell cycle OR cell proliferation;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	""	"Pf10189"	"65123"	"ENSG00000143624; ENSG00000262826"	"INTS3"	"A8K1W0; B4DQC8; B4E3U9; D3DV57; hsa:65123; Q4G0E5; Q5VUQ5; Q5VUQ6; Q5VUR0; Q5VUR1; Q68DJ1; Q68E01; Q69YR5; Q6AI57; Q6DKG7; Q6MZQ4; Q6MZZ9; Q8NC46; Q8TB23; Q9H6S9"	"RNA polymerase II transcribes snRNA genes"	""	"1"	"0"	"25.3"	"15.1"	"40.0"	"31.6"	"26.6"	"22.8"	"40.3"	"9.0"	"13.7"	"14.7"	"12.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P36957"	"Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLST PE=1 SV=4"	"3"	"2"	"3"	"2"	"453"	"48.7"	"8.95"	"604.70"	"2.51"	"2"	"1"	"protein metabolism;other metabolic processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00198, Pf00364"	"1743"	"ENSG00000119689"	"DLST"	"B7Z5W8; E7ESY5; hsa:1743; P36957; Q7LDY7; Q9BQ32"	"Glyoxylate metabolism and glycine degradation; Lysine catabolism; Citric acid cycle (TCA cycle)"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Metabolic reprogramming in colon cancer; 7q11.23 copy number variation syndrome; 1p36 copy number variation syndrome; 10q11.21q11.23 copy number variation syndrome; TCA cycle (aka Krebs or citric acid cycle)"	"10"	"0"	"306.2"	"292.0"	"806.8"	"267.6"	"241.6"	"217.7"	"793.4"	"116.0"	"193.2"	"114.9"	"137.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75530"	"Polycomb protein EED OS=Homo sapiens OX=9606 GN=EED PE=1 SV=2"	"2"	"1"	"2"	"1"	"441"	"50.2"	"7.03"	"254.10"	"2.51"	"1"	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00400"	"8726"	"ENSG00000074266"	"EED"	"A8K7V5; hsa:8726; O00149; O75530; Q6NTH2; Q7LDA5; Q7LDG8; Q86VV2; Q9UNY7"	"HCMV Early Events; Oxidative Stress Induced Senescence; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6; Activation of anterior HOX genes in hindbrain development during early embryogenesis; PKMTs methylate histone lysines; PRC2 methylates histones and DNA; Defective pyroptosis"	"Histone modifications; Interactome of polycomb repressive complex 2 (PRC2) ; Tumor suppressor activity of SMARCB1; Epithelial to mesenchymal transition in colorectal cancer; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; Pleural mesothelioma"	"14"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"P26583"	"High mobility group protein B2 OS=Homo sapiens OX=9606 GN=HMGB2 PE=1 SV=2"	"10"	"2"	"3"	"2"	"209"	"24.0"	"7.81"	"844.79"	"2.51"	"2"	"1"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00505, Pf09011"	"3148"	"ENSG00000164104"	"HMGB2"	"B2R4K8; D3DP37; hsa:3148; P26583; Q5U072"	"Apoptosis induced DNA fragmentation"	"Retinoblastoma gene in cancer; Ectoderm differentiation; Ectoderm differentiation"	"4"	"0"	"325.4"	"294.5"	"1010.4"	"282.8"	"177.6"	"194.3"	"537.9"	"84.0"	"186.1"	"168.1"	"175.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IWZ6"	"Bardet-Biedl syndrome 7 protein OS=Homo sapiens OX=9606 GN=BBS7 PE=1 SV=2"	"1"	"1"	"2"	"1"	"715"	"80.3"	"6.05"	"338.98"	"2.51"	"1"	"1"	"cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	""	"55212"	"ENSG00000138686"	"BBS7"	"hsa:55212; Q4W5P8; Q8IWZ6; Q8N581; Q9NVI4"	"BBSome-mediated cargo-targeting to cilium"	"Ciliary landscape; Genes related to primary cilium development (based on CRISPR); Joubert syndrome; Ciliopathies; Bardet-Biedl syndrome"	"6"	"0"	"42.4"	"44.8"	"158.7"	"44.1"	"41.7"	"40.3"	"162.6"	"53.0"	"163.4"	"220.5"	"279.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WXH0"	"Nesprin-2 OS=Homo sapiens OX=9606 GN=SYNE2 PE=1 SV=3"	"0"	"1"	"2"	"1"	"6885"	"795.9"	"5.36"	"235.70"	"2.50"	"1"	"1"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00435, Pf10541"	"23224"	"ENSG00000054654"	"SYNE2"	"B4DND7; B4DPR6; hsa:23224; I6XXQ5; Q540G1; Q86YP9; Q8N1S3; Q8NF49; Q8TER7; Q8WWW3; Q8WWW4; Q8WWW5; Q8WXH0; Q8WXH1; Q9NU50; Q9UFQ4; Q9Y2L4; Q9Y4R1"	"Meiotic synapsis"	"Ovarian infertility; Rett syndrome causing genes; Envelope proteins and their potential roles in EDMD physiopathology"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P0U4"	"CXXC-type zinc finger protein 1 OS=Homo sapiens OX=9606 GN=CXXC1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"656"	"75.7"	"8.24"	"256.19"	"2.50"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00628, Pf02008, Pf12269"	"30827"	"ENSG00000154832"	"CXXC1"	"B2RC03; hsa:30827; Q8N2W4; Q96BC8; Q9P0U4; Q9P2V7"	"XBP1(S) activates chaperone genes; Formation of WDR5-containing histone-modifying complexes"	"Male infertility"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q15645"	"Pachytene checkpoint protein 2 homolog OS=Homo sapiens OX=9606 GN=TRIP13 PE=1 SV=2"	"3"	"1"	"2"	"1"	"432"	"48.5"	"6.09"	"240.71"	"2.50"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00004"	"9319"	"ENSG00000071539"	"TRIP13"	"C9K0T3; D3DTC0; hsa:9319; O15324; Q15645"	""	"Male infertility"	"1"	"0"	"56.9"	"51.8"	"233.0"	"45.4"	"49.2"	"23.4"	"167.0"	"12.3"	"19.6"	"19.1"	"18.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5Z4"	"Heme-binding protein 2 OS=Homo sapiens OX=9606 GN=HEBP2 PE=1 SV=1"	"6"	"1"	"2"	"1"	"205"	"22.9"	"4.63"	"350.78"	"2.50"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"non-structural extracellular;mitochondrion;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf04832"	"23593"	"ENSG00000051620"	"HEBP2"	"hsa:23593; Q96P57; Q9Y5Z4"	"Neutrophil degranulation"	""	"1"	"0"	"13.2"	"18.6"	"61.5"	"12.0"	"10.1"	"6.9"	"85.3"	"8.8"	"8.5"	"4.4"	"3.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A0A087WV53"	"SPEG neighbor protein OS=Homo sapiens OX=9606 GN=SPEGNB PE=4 SV=1"	"7"	"1"	"1"	"1"	"238"	"26.1"	"5.60"	""	"2.50"	""	"1"	""	""	""	"Pf00612, Pf07679"	"100996693"	"ENSG00000286095"	"SPEGNB"	"A0A087WV53; hsa:100996693"	""	""	"0"	"0"	"24.4"	"26.9"	"223.3"	"36.5"	"29.4"	"18.1"	"226.5"	"8.5"	"11.1"	"8.7"	"6.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P16383"	"GC-rich sequence DNA-binding factor 2 OS=Homo sapiens OX=9606 GN=GCFC2 PE=1 SV=2"	"1"	"1"	"2"	"1"	"781"	"89.3"	"5.99"	"328.04"	"2.49"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity"	"Pf07842"	"6936"	"ENSG00000005436"	"GCFC2"	"A4UHQ8; A4UHQ9; hsa:6936; O95032; P16383; Q53TY0; Q6P2F2"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"46.0"	"53.2"	"146.6"	"44.7"	"47.4"	"50.5"	"161.9"	"23.1"	"38.1"	"35.2"	"40.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P20585"	"DNA mismatch repair protein Msh3 OS=Homo sapiens OX=9606 GN=MSH3 PE=1 SV=4"	"1"	"1"	"2"	"1"	"1137"	"127.3"	"8.02"	"363.57"	"2.49"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00488, Pf01624, Pf05188, Pf05192"	"4437"	"ENSG00000113318"	"MSH3"	"A1L480; A1L482; A6NMM6; hsa:4437; P20585; Q6PJT5; Q86UQ6; Q92867"	"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta); Defective Mismatch Repair Associated With MSH3; Defective Mismatch Repair Associated With MSH2"	"Chromosomal and microsatellite instability in colorectal cancer ; DNA repair pathways, full network"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13724"	"Mannosyl-oligosaccharide glucosidase OS=Homo sapiens OX=9606 GN=MOGS PE=1 SV=5"	"3"	"1"	"1"	"1"	"837"	"91.9"	"8.90"	""	"2.49"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf03200, Pf16923"	"7841"	"ENSG00000115275"	"MOGS"	"A8K938; F5H6D0; hsa:7841; Q13724; Q17RN9; Q8TCT5"	"Maturation of spike protein; N-glycan trimming in the ER and Calnexin/Calreticulin cycle; Maturation of spike protein; Defective MOGS causes CDG-2b"	"N-glycan biosynthesis"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q8IW35"	"Centrosomal protein of 97 kDa OS=Homo sapiens OX=9606 GN=CEP97 PE=1 SV=1"	"2"	"1"	"2"	"1"	"865"	"96.9"	"5.02"	"309.08"	"2.49"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf14580"	"79598"	"ENSG00000182504"	"CEP97"	"B5MDY8; hsa:79598; Q8IW35; Q8NA71; Q9H5T9"	"Anchoring of the basal body to the plasma membrane; RHOV GTPase cycle"	"Ciliary landscape; Genes related to primary cilium development (based on CRISPR); Joubert syndrome"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q15031"	"Probable leucine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=LARS2 PE=1 SV=2"	"1"	"1"	"1"	"1"	"903"	"101.9"	"8.22"	""	"2.49"	""	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00133, Pf08264"	"23395"	"ENSG00000011376"	"LARS2"	"hsa:23395; Q15031"	"Mitochondrial tRNA aminoacylation"	"Amino acid metabolism; IL-18 signaling pathway; Primary ovarian insufficiency"	"4"	"0"	"13.2"	"12.3"	"43.6"	"6.5"	"6.2"	"8.1"	"39.1"	"2.5"	"8.5"	"4.1"	"5.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14530"	"Thioredoxin domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TXNDC9 PE=1 SV=2"	"5"	"1"	"2"	"1"	"226"	"26.5"	"5.88"	"314.47"	"2.49"	"1"	"1"	"cell organization and biogenesis"	"cytosol;cytoskeleton;nucleus;other cell component"	""	"Pf00085"	"10190"	"ENSG00000115514"	"TXNDC9"	"B2R9G8; D3DVI4; hsa:10190; O14530; Q53HG4; Q53RV8; Q6NSF5; Q8TB70; Q9BRU6"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y399"	"28S ribosomal protein S2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"296"	"33.2"	"9.26"	"307.89"	"2.49"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00318"	"51116"	"ENSG00000122140"	"MRPS2"	"hsa:51116; Q5T899; Q9BSQ4; Q9Y399"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"89.8"	"84.4"	"285.0"	"93.7"	"76.2"	"87.6"	"291.5"	"37.3"	"58.8"	"56.3"	"51.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92783"	"Signal transducing adapter molecule 1 OS=Homo sapiens OX=9606 GN=STAM PE=1 SV=3"	"1"	"1"	"2"	"1"	"540"	"59.1"	"4.82"	"336.65"	"2.49"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;signal transduction;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00018, Pf00790, Pf02809"	"8027"	"ENSG00000136738"	"STAM"	"B0YJ99; D3DRU5; hsa:8027; Q8N6D9; Q92783"	"Cargo recognition for clathrin-mediated endocytosis; Endosomal Sorting Complex Required For Transport (ESCRT); RHOU GTPase cycle; Metalloprotease DUBs; EGFR downregulation; Negative regulation of MET activity; InlB-mediated entry of Listeria monocytogenes into host cell"	"Vitamin D receptor pathway; VEGFA-VEGFR2 signaling; EGF/EGFR signaling pathway"	"11"	"0"	"12.6"	"20.7"	"75.7"	"14.6"	"11.5"	"13.3"	"94.5"	"10.3"	"19.3"	"12.0"	"14.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43396"	"Thioredoxin-like protein 1 OS=Homo sapiens OX=9606 GN=TXNL1 PE=1 SV=3"	"4"	"1"	"1"	"1"	"289"	"32.2"	"4.96"	""	"2.48"	""	"1"	""	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00085, Pf06201"	"9352"	"ENSG00000091164"	"TXNL1"	"hsa:9352; O43396"	"RND2 GTPase cycle; RHOV GTPase cycle; RHOU GTPase cycle; RND3 GTPase cycle; RND1 GTPase cycle; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle"	""	"7"	"0"	"23.0"	"22.3"	"113.7"	"34.4"	"23.7"	"20.1"	"152.4"	"22.4"	"37.5"	"26.9"	"24.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96IV0"	"Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase OS=Homo sapiens OX=9606 GN=NGLY1 PE=1 SV=1"	"2"	"1"	"2"	"1"	"654"	"74.3"	"6.89"	"272.53"	"2.48"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01841, Pf04721, Pf09409"	"55768"	"ENSG00000151092"	"NGLY1"	"B4DJE9; hsa:55768; Q59FB1; Q6PJD8; Q96IV0; Q9BVR8; Q9NR70"	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96GG9"	"DCN1-like protein 1 OS=Homo sapiens OX=9606 GN=DCUN1D1 PE=1 SV=1"	"8"	"2"	"3"	"2"	"259"	"30.1"	"5.34"	"500.76"	"2.48"	"2"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf03556, Pf14555"	"54165"	"ENSG00000043093"	"DCUN1D1"	"B2RB37; hsa:54165; Q7L3G9; Q8TEX7; Q96GG9; Q9H6M1; Q9HCT3"	"Neddylation"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"P48201"	"ATP synthase F(0) complex subunit C3, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5MC3 PE=1 SV=1"	"5"	"1"	"2"	"1"	"142"	"14.7"	"9.45"	"310.42"	"2.48"	"1"	"1"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00137"	"518"	"ENSG00000154518"	"ATP5MC3"	"B2R4Z0; D3DPF0; hsa:518; P48201; Q4ZFX7"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"Electron transport chain: OXPHOS system in mitochondria; 7q11.23 copy number variation syndrome; Oxidative phosphorylation"	"5"	"0"	"205.9"	"220.5"	"578.2"	"176.4"	"155.9"	"150.7"	"612.1"	"141.9"	"217.5"	"223.8"	"289.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9ULC4"	"Malignant T-cell-amplified sequence 1 OS=Homo sapiens OX=9606 GN=MCTS1 PE=1 SV=1"	"7"	"1"	"2"	"1"	"181"	"20.5"	"8.82"	"276.28"	"2.48"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"other cell component"	"nucleic acid binding activity"	"Pf01472, Pf17832"	"28985"	"ENSG00000232119; ENSG00000288295"	"MCTS1"	"B4DGY2; hsa:28985; Q502X6; Q9ULC4"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"P26038"	"Moesin OS=Homo sapiens OX=9606 GN=MSN PE=1 SV=3"	"6"	"3"	"4"	"2"	"577"	"67.8"	"6.40"	"1293.58"	"2.47"	"3"	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00373, Pf00769, Pf09379, Pf09380, Pf20492"	"4478"	"ENSG00000147065"	"MSN"	"hsa:4478; P26038"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Recycling pathway of L1; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Signaling by ALK fusions and activated point mutants"	"Glial cell differentiation; AGE/RAGE pathway; Measles virus infection; 16p11.2 proximal deletion syndrome; Regulation of actin cytoskeleton"	"10"	"0"	"159.1"	"149.9"	"744.9"	"167.5"	"104.7"	"86.5"	"158.8"	"51.3"	"87.7"	"63.0"	"65.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14795"	"Protein unc-13 homolog B OS=Homo sapiens OX=9606 GN=UNC13B PE=1 SV=2"	"2"	"2"	"2"	"2"	"1591"	"180.6"	"5.99"	"240.31"	"2.47"	"1"	"1"	"cell-cell signaling;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00130, Pf00168, Pf06292"	"10497"	"ENSG00000198722"	"UNC13B"	"hsa:10497; O14795; Q2NKJ5; Q5VYM8"	"Glutamate Neurotransmitter Release Cycle; Serotonin Neurotransmitter Release Cycle; Norepinephrine Neurotransmitter Release Cycle; Dopamine Neurotransmitter Release Cycle; Acetylcholine Neurotransmitter Release Cycle"	"Synaptic vesicle pathway; 16p11.2 proximal deletion syndrome; Monoamine transport"	"8"	"0"	"3.0"	"0.0"	"6.3"	"0.0"	"2.2"	"0.0"	"10.7"	"4.2"	"19.9"	"36.5"	"37.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBC2"	"Epidermal growth factor receptor substrate 15-like 1 OS=Homo sapiens OX=9606 GN=EPS15L1 PE=1 SV=1"	"4"	"3"	"4"	"3"	"864"	"94.2"	"5.11"	"775.18"	"2.47"	"3"	"1"	"transport"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf12763"	"58513"	"ENSG00000127527"	"EPS15L1"	"A2RRF3; A5PL29; B4DKA3; hsa:58513; Q9UBC2"	"Cargo recognition for clathrin-mediated endocytosis; EGFR downregulation"	"EGF/EGFR signaling pathway"	"4"	"0"	"23.8"	"29.4"	"91.2"	"37.2"	"35.7"	"30.8"	"99.6"	"11.0"	"23.1"	"15.9"	"20.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NX55"	"Huntingtin-interacting protein K OS=Homo sapiens OX=9606 GN=HYPK PE=1 SV=2"	"6"	"1"	"2"	"1"	"129"	"14.7"	"4.93"	"332.66"	"2.46"	"1"	"1"	"other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf04419, Pf19026"	"100137436; 101127706; 104002286; 104679625; 105491324; 105549422; 105588143; 108521295; 25764; 713266"	"ENSCATG00000038565; ENSGGOG00000014809; ENSMFAG00000057677; ENSMLEG00000000898; ENSMMUG00000022768; ENSMNEG00000018318; ENSPANG00000018102; ENSPPAG00000034659; ENSPTEG00000009792; ENSPTEG00000019135; ENSPTRG00000038721; ENSRBIG00000028237; ENSRROG00000039445; ENSTGEG00000007663"	"HYPK; LOC113219833"	"A0A024R5Q1; A0A1D5R5K3; A0A2I2YQJ1; A0A2J8NTT0; A0A2K5N035; A0A2K5TR12; A0A2K5XAQ0; A0A2K6AXP0; A0A2K6KBN5; A0A2K6QRU2; A0A2R9B6N1; A0A663DGD1; A0A6D2Y1W8; A0A8C9GZF6; A0A8D2ERJ4; A0A8J8XMG0; A9X1C4; F7GC11; G7MX15; G7PB77; H2Q9B3; hsa:25764; mcc:713266; mleu:105549422; mni:105491324; panu:100137436; ptr:104002286; rbb:108521295; rro:104679625"	""	""	"0"	"0"	"88.9"	"92.7"	"358.5"	"84.3"	"58.4"	"47.4"	"239.2"	"39.1"	"67.8"	"48.2"	"56.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P98082"	"Disabled homolog 2 OS=Homo sapiens OX=9606 GN=DAB2 PE=1 SV=3"	"1"	"1"	"1"	"1"	"770"	"82.4"	"5.53"	""	"2.46"	""	"1"	"cell-cell signaling;cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00640"	"1601"	"ENSG00000153071"	"DAB2"	"A6NES5; hsa:1601; P98082; Q13598; Q9BTY0; Q9UK04"	"Cargo recognition for clathrin-mediated endocytosis; Formation of annular gap junctions"	"Endoderm differentiation"	"5"	"0"	"13.1"	"9.5"	"32.3"	"9.0"	"8.0"	"10.4"	"30.5"	"8.5"	"32.5"	"26.5"	"38.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49792"	"E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2"	"1"	"3"	"4"	"2"	"3224"	"358.0"	"6.20"	"993.22"	"2.46"	"3"	"1"	"protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00160, Pf00638, Pf00641, Pf12185"	"5903"	"ENSG00000153201"	"RANBP2"	"hsa:5903; P49792; Q13074; Q15280; Q53TE2; Q59FH7"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Signaling by ALK fusions and activated point mutants; tRNA processing in the nucleus; Rev-mediated nuclear export of HIV RNA; HCMV Late Events; HCMV Early Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"	""	"35"	"0"	"51.7"	"57.7"	"185.1"	"55.8"	"46.8"	"40.7"	"212.0"	"31.9"	"43.7"	"34.4"	"35.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14571"	"Inositol 1,4,5-trisphosphate receptor type 2 OS=Homo sapiens OX=9606 GN=ITPR2 PE=1 SV=2"	"1"	"3"	"4"	"2"	"2701"	"307.9"	"6.43"	"766.43"	"2.46"	"3"	"1"	"stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf00520, Pf01365, Pf02815, Pf08454, Pf08709"	"3709"	"ENSG00000123104"	"ITPR2"	"hsa:3709; O94773; Q14571"	"Role of phospholipids in phagocytosis; FCERI mediated Ca+2 mobilization; FCGR3A-mediated IL10 synthesis; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Ion homeostasis; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Ca2+ pathway; VEGFR2 mediated cell proliferation; Elevation of cytosolic Ca2+ levels; PLC beta mediated events; DAG and IP3 signaling; CLEC7A (Dectin-1) induces NFAT activation; Effects of PIP2 hydrolysis"	"Alzheimer's disease and miRNA effects; Myometrial relaxation and contraction pathways; Vitamin D-sensitive calcium signaling in depression; Thyroid hormones production and peripheral downstream signaling effects; Alzheimer's disease; GDNF signaling; Calcium regulation in cardiac cells"	"21"	"0"	"291.1"	"274.6"	"632.5"	"218.3"	"186.2"	"168.6"	"420.8"	"72.1"	"144.0"	"129.3"	"159.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NVC6"	"Mediator of RNA polymerase II transcription subunit 17 OS=Homo sapiens OX=9606 GN=MED17 PE=1 SV=2"	"2"	"1"	"2"	"1"	"651"	"72.8"	"7.44"	"296.90"	"2.45"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf10156"	"9440"	"ENSG00000042429"	"MED17"	"B3KN07; hsa:9440; Q9HA81; Q9NVC6; Q9UNP7; Q9Y2W0; Q9Y660"	"PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; Generic Transcription Pathway"	""	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"P48729"	"Casein kinase I isoform alpha OS=Homo sapiens OX=9606 GN=CSNK1A1 PE=1 SV=2"	"3"	"1"	"2"	"1"	"337"	"38.9"	"9.57"	"249.67"	"2.45"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"1452"	"ENSG00000113712"	"CSNK1A1"	"D3DQG0; D3DQG1; hsa:1452; P48729; Q4JJA0; Q5U046; Q5U047; Q6FGA2; Q71TU5; Q96HD2; Q9UDK3"	"Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Activation of SMO; Disassembly of the destruction complex and recruitment of AXIN to the membrane; Beta-catenin phosphorylation cascade; Signaling by GSK3beta mutants; CTNNB1 S33 mutants aren't phosphorylated; CTNNB1 S37 mutants aren't phosphorylated; CTNNB1 S45 mutants aren't phosphorylated; CTNNB1 T41 mutants aren't phosphorylated; APC truncation mutants have impaired AXIN binding; AXIN missense mutants destabilize the destruction complex; Truncations of AMER1 destabilize the destruction complex; Maturation of nucleoprotein"	"Alzheimer's disease and miRNA effects; T cell receptor and co-stimulatory signaling; Complement system; Wnt signaling pathway; Wnt/beta-catenin signaling pathway in leukemia; Regulation of Wnt / B-catenin signaling by small molecule compounds; Chromosomal and microsatellite instability in colorectal cancer ; Hedgehog signaling pathway; lncRNA in canonical Wnt signaling and colorectal cancer; Breast cancer pathway; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Influence of laminopathies on Wnt signaling; Overlap between signal transduction pathways contributing to LMNA laminopathies; Pleural mesothelioma; Alzheimer's disease; DYRK1A involvement regarding cell proliferation in brain development"	"32"	"0"	"8.0"	"13.4"	"25.3"	"11.1"	"13.4"	"6.8"	"24.9"	"5.9"	"8.0"	"9.7"	"4.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01813"	"ATP-dependent 6-phosphofructokinase, platelet type OS=Homo sapiens OX=9606 GN=PFKP PE=1 SV=2"	"3"	"2"	"3"	"1"	"784"	"85.5"	"7.55"	"487.51"	"2.45"	"2"	"1"	"other metabolic processes;other biological processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00365"	"5214"	"ENSG00000067057"	"PFKP"	"B3KS15; hsa:5214; Q01813; Q5VSR7; Q5VSR8"	"Glycolysis"	"Cori cycle; Clear cell renal cell carcinoma pathways; Glucose metabolism in triple-negative breast cancer cells; Glycolysis and gluconeogenesis"	"5"	"0"	"33.6"	"39.0"	"109.9"	"35.1"	"30.9"	"25.9"	"98.2"	"21.5"	"29.3"	"30.6"	"22.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IX18"	"Probable ATP-dependent RNA helicase DHX40 OS=Homo sapiens OX=9606 GN=DHX40 PE=1 SV=2"	"2"	"1"	"2"	"1"	"779"	"88.5"	"8.65"	"367.76"	"2.45"	"1"	"1"	""	""	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"79665"	"ENSG00000108406"	"DHX40"	"B3KTJ5; C9JR60; hsa:79665; Q5JPH4; Q8IX18; Q8TC86; Q8WY53; Q9BXM1; Q9H6M9"	""	""	"0"	"0"	"17.3"	"14.6"	"65.1"	"16.1"	"11.1"	"14.7"	"49.6"	"5.0"	"7.1"	"11.7"	"13.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43665"	"Regulator of G-protein signaling 10 OS=Homo sapiens OX=9606 GN=RGS10 PE=1 SV=3"	"6"	"1"	"2"	"1"	"181"	"21.2"	"7.49"	"300.75"	"2.45"	"1"	"1"	"cell-cell signaling;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00615"	"6001"	"ENSG00000148908"	"RGS10"	"A8K408; B1AMR8; hsa:6001; O43665; Q6IAZ6; Q96GN0"	"G alpha (i) signalling events"	"Mesodermal commitment pathway; Myometrial relaxation and contraction pathways; Calcium regulation in cardiac cells"	"4"	"0"	"7.0"	"8.2"	"52.3"	"6.5"	"5.2"	"2.6"	"70.2"	"3.9"	"10.6"	"6.3"	"5.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00154"	"Cytosolic acyl coenzyme A thioester hydrolase OS=Homo sapiens OX=9606 GN=ACOT7 PE=1 SV=3"	"3"	"1"	"2"	"1"	"380"	"41.8"	"8.54"	"302.51"	"2.45"	"1"	"1"	"other metabolic processes"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf03061"	"11332"	"ENSG00000097021"	"ACOT7"	"A8K0K7; A8K232; A8K6B8; A8K837; B3KQ12; hsa:11332; O00154; O43703; Q53Y78; Q5JYL2; Q5JYL3; Q5JYL4; Q5JYL5; Q5JYL6; Q5TGR4; Q9UJM9; Q9Y539; Q9Y540"	"Mitochondrial Fatty Acid Beta-Oxidation"	""	"1"	"0"	"26.3"	"33.5"	"131.5"	"33.5"	"25.3"	"16.0"	"130.7"	"17.4"	"24.9"	"24.0"	"13.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P57088"	"Transmembrane protein 33 OS=Homo sapiens OX=9606 GN=TMEM33 PE=1 SV=2"	"4"	"1"	"2"	"1"	"247"	"28.0"	"9.70"	"335.97"	"2.45"	"1"	"1"	"cell organization and biogenesis;stress response;other biological processes"	"other membranes;ER/Golgi;nucleus;other cell component"	""	"Pf03661"	"55161"	"ENSG00000109133"	"TMEM33"	"B3KSS8; hsa:55161; P57088; Q9H953"	""	""	"0"	"0"	"13.9"	"19.2"	"65.4"	"14.6"	"10.1"	"7.6"	"47.3"	"4.0"	"6.2"	"4.3"	"4.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HB40"	"Retinoid-inducible serine carboxypeptidase OS=Homo sapiens OX=9606 GN=SCPEP1 PE=1 SV=1"	"2"	"1"	"1"	"1"	"452"	"50.8"	"5.81"	""	"2.45"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol"	"other molecular function"	"Pf00450"	"59342"	"ENSG00000121064"	"SCPEP1"	"hsa:59342; Q96A94; Q9H3F0; Q9HB40"	""	""	"0"	"0"	"9.4"	"9.5"	"49.8"	"8.1"	"6.7"	"2.6"	"32.1"	"2.9"	"6.7"	"9.5"	"10.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16836"	"Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=HADH PE=1 SV=3"	"5"	"2"	"3"	"2"	"314"	"34.3"	"8.85"	"506.03"	"2.45"	"2"	"1"	"other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00725, Pf02737"	"3033"	"ENSG00000138796"	"HADH"	"hsa:3033; J3KQ17; O00324; O00397; O00753; Q16836; Q4W5B4"	"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA; Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of butanoyl-CoA to acetyl-CoA; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA"	"Fatty acid beta-oxidation; Fatty acid biosynthesis; Mitochondrial long chain fatty acid beta-oxidation; Amino acid metabolism; IL-18 signaling pathway; Mitochondrial fatty acid oxidation disorders"	"11"	"0"	"78.9"	"80.2"	"394.3"	"108.3"	"61.2"	"41.4"	"355.9"	"51.4"	"107.1"	"96.0"	"151.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H3G5"	"Probable serine carboxypeptidase CPVL OS=Homo sapiens OX=9606 GN=CPVL PE=1 SV=2"	"3"	"1"	"2"	"1"	"476"	"54.1"	"5.62"	"354.76"	"2.45"	"1"	"1"	"protein metabolism"	""	"other molecular function"	"Pf00450"	"54504"	"ENSG00000106066"	"CPVL"	"A4D1A4; hsa:54504; Q6UX20; Q8NBL7; Q96AR7; Q9H3G5; Q9HB41"	""	""	"0"	"0"	"25.6"	"17.1"	"67.1"	"15.3"	"11.4"	"11.3"	"38.5"	"10.9"	"7.9"	"7.6"	"7.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86YP4"	"Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1"	"2"	"1"	"2"	"1"	"633"	"68.0"	"9.94"	"310.99"	"2.44"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00320, Pf16563"	"54815"	"ENSG00000167491"	"GATAD2A"	"B5MC40; hsa:54815; Q7L3J2; Q86YP4; Q96F28; Q9NPU2; Q9NXS1"	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; RNA Polymerase I Transcription Initiation; Potential therapeutics for SARS; Regulation of PTEN gene transcription; HDACs deacetylate histones; Regulation of TP53 Activity through Acetylation"	""	"6"	"0"	"5.8"	"7.1"	"30.9"	"5.1"	"5.2"	"5.2"	"37.5"	"4.5"	"5.1"	"4.4"	"3.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A3KMH1"	"von Willebrand factor A domain-containing protein 8 OS=Homo sapiens OX=9606 GN=VWA8 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1905"	"214.7"	"7.40"	"279.16"	"2.44"	"1"	"1"	""	"mitochondrion;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf07728"	"23078"	"ENSG00000102763"	"VWA8"	"A3KMH1; hsa:23078; O60310; Q5JTP6; Q5VW08; Q7Z6I9; Q86YC9; Q8N3E4"	""	""	"0"	"0"	"21.6"	"29.8"	"64.2"	"20.0"	"21.6"	"14.7"	"70.3"	"11.3"	"14.4"	"12.4"	"14.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P67870"	"Casein kinase II subunit beta OS=Homo sapiens OX=9606 GN=CSNK2B PE=1 SV=1"	"9"	"1"	"2"	"1"	"215"	"24.9"	"5.55"	"283.43"	"2.44"	"1"	"1"	"cell-cell signaling;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;kinase activity;other molecular function"	"Pf01214"	"1460"	"ENSG00000204435; ENSG00000206406; ENSG00000224398; ENSG00000224774; ENSG00000228875; ENSG00000230700; ENSG00000232960"	"CSNK2B"	"B0UXA9; hsa:1460; P07312; P13862; P67870; Q4VX47"	"Regulation of PTEN stability and activity; KEAP1-NFE2L2 pathway; Neutrophil degranulation; Condensation of Prometaphase Chromosomes; Regulation of TP53 Activity through Phosphorylation; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; WNT mediated activation of DVL; Signal transduction by L1; Receptor Mediated Mitophagy; Synthesis of PC"	"Alzheimer's disease and miRNA effects; lncRNA in canonical Wnt signaling and colorectal cancer; Breast cancer pathway; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Measles virus infection; Pleural mesothelioma; Alzheimer's disease"	"19"	"0"	"15.5"	"18.3"	"75.4"	"16.7"	"20.1"	"11.0"	"93.1"	"6.7"	"15.7"	"9.8"	"13.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q969N2"	"GPI transamidase component PIG-T OS=Homo sapiens OX=9606 GN=PIGT PE=1 SV=1"	"2"	"1"	"2"	"1"	"578"	"65.7"	"8.38"	"292.86"	"2.44"	"1"	"1"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"other membranes;ER/Golgi;other cell component"	""	"Pf04113"	"51604"	"ENSG00000124155"	"PIGT"	"B2RND5; B7Z3N1; B7Z7I8; E1P622; G8JLF5; hsa:51604; Q2NL69; Q7Z3N7; Q969N2; Q9BQY7; Q9BQY8; Q9UJG6; Q9Y2Z5"	"Attachment of GPI anchor to uPAR"	"IL-18 signaling pathway"	"2"	"0"	"9.9"	"12.5"	"39.0"	"8.2"	"7.2"	"9.9"	"37.1"	"4.3"	"6.1"	"6.7"	"8.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N3U4"	"Cohesin subunit SA-2 OS=Homo sapiens OX=9606 GN=STAG2 PE=1 SV=3"	"1"	"1"	"2"	"1"	"1231"	"141.2"	"5.43"	"342.29"	"2.44"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf08514"	"10735"	"ENSG00000101972"	"STAG2"	"B1AMT5; D3DTF5; hsa:10735; O00540; Q5JTI6; Q68DE9; Q8N3U4; Q9H1N8"	"Separation of Sister Chromatids; SUMOylation of DNA damage response and repair proteins; Resolution of Sister Chromatid Cohesion; Meiotic synapsis; Estrogen-dependent gene expression; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"Cell cycle; Cohesin complex - Cornelia de Lange syndrome"	"9"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q96BW9"	"Phosphatidate cytidylyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=TAMM41 PE=1 SV=2"	"3"	"1"	"2"	"1"	"452"	"51.0"	"7.94"	"298.17"	"2.44"	"1"	"1"	"other metabolic processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf09139"	"132001"	"ENSG00000144559"	"TAMM41"	"B4DIY7; C9J2U4; hsa:132001; Q96BW9"	""	""	"0"	"0"	"16.3"	"11.3"	"53.5"	"15.5"	"10.2"	"10.1"	"46.0"	"4.6"	"11.8"	"7.4"	"6.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75909"	"Cyclin-K OS=Homo sapiens OX=9606 GN=CCNK PE=1 SV=2"	"3"	"1"	"1"	"1"	"580"	"64.2"	"8.41"	""	"2.44"	""	"1"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00134"	"8812"	"ENSG00000090061"	"CCNK"	"hsa:8812; O75909; Q59FT6; Q86U16; Q96B63; Q9NNY9"	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes"	"Male infertility"	"10"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A6NCE7"	"Microtubule-associated proteins 1A/1B light chain 3 beta 2 OS=Homo sapiens OX=9606 GN=MAP1LC3B2 PE=2 SV=1"	"14"	"2"	"2"	"2"	"125"	"14.6"	"8.68"	"249.87"	"2.44"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;stress response"	"other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02991"	"643246"	"ENSG00000258102"	"MAP1LC3B2"	"A6NCE7; hsa:643246"	""	""	"0"	"0"	"109.5"	"129.9"	"385.0"	"135.5"	"138.2"	"117.4"	"480.8"	"125.8"	"216.9"	"212.9"	"281.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7LBC6"	"Lysine-specific demethylase 3B OS=Homo sapiens OX=9606 GN=KDM3B PE=1 SV=2"	"1"	"1"	"2"	"1"	"1761"	"191.5"	"7.18"	"394.18"	"2.43"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02373"	"51780"	"ENSG00000120733"	"KDM3B"	"A6H8X7; hsa:51780; Q7LBC6; Q9BVH6; Q9BW93; Q9BZ52; Q9NYF4; Q9UPS0"	"HDMs demethylate histones"	"Thermogenesis"	"2"	"0"	"58.9"	"75.6"	"259.2"	"55.1"	"50.5"	"44.9"	"288.1"	"37.1"	"42.9"	"39.8"	"44.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23786"	"Carnitine O-palmitoyltransferase 2, mitochondrial OS=Homo sapiens OX=9606 GN=CPT2 PE=1 SV=2"	"2"	"1"	"2"	"1"	"658"	"73.7"	"8.18"	"287.80"	"2.43"	"1"	"1"	"other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf00755"	"1376"	"ENSG00000157184"	"CPT2"	"B2R6S0; hsa:1376; P23786; Q5SW68; Q9BQ26"	"PPARA activates gene expression; Carnitine metabolism"	"Fatty acid beta-oxidation; PPAR-alpha pathway; Nuclear receptors meta-pathway; Mitochondrial long chain fatty acid beta-oxidation; PPAR signaling pathway; Thermogenesis; Mitochondrial fatty acid oxidation disorders"	"9"	"0"	"9.5"	"9.1"	"46.9"	"9.0"	"1.9"	"4.6"	"48.1"	"6.8"	"8.8"	"5.5"	"8.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P15374"	"Ubiquitin carboxyl-terminal hydrolase isozyme L3 OS=Homo sapiens OX=9606 GN=UCHL3 PE=1 SV=1"	"4"	"1"	"2"	"1"	"230"	"26.2"	"4.92"	"316.78"	"2.43"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01088"	"7347"	"ENSG00000118939"	"UCHL3"	"B2R970; hsa:7347; P15374; Q5TBK8; Q6IBE9"	"UCH proteinases; Neddylation; Synthesis of active ubiquitin: roles of E1 and E2 enzymes"	"Proteasome degradation"	"4"	"0"	"74.2"	"85.1"	"351.4"	"74.6"	"56.3"	"48.9"	"480.7"	"40.2"	"53.7"	"40.8"	"41.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A6ZKI3"	"Retrotransposon Gag-like protein 8C OS=Homo sapiens OX=9606 GN=RTL8C PE=1 SV=1"	"11"	"1"	"2"	"1"	"113"	"13.2"	"5.07"	"254.39"	"2.43"	"1"	"1"	""	""	""	"Pf16297"	"8933"	"ENSG00000134590"	"RTL8C"	"A6ZKI3; hsa:8933"	""	""	"0"	"0"	"28.4"	"30.9"	"108.8"	"28.6"	"26.7"	"21.2"	"113.5"	"19.1"	"24.8"	"19.2"	"19.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBF8"	"Phosphatidylinositol 4-kinase beta OS=Homo sapiens OX=9606 GN=PI4KB PE=1 SV=1"	"1"	"1"	"2"	"1"	"816"	"91.3"	"6.25"	"308.04"	"2.43"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport;signal transduction"	"other membranes;cytosol;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf00454"	"5298"	"ENSG00000143393"	"PI4KB"	"B4DGI2; hsa:5298; O15096; P78405; Q5VWB9; Q5VWC0; Q5VWC1; Q9BWR6; Q9UBF8"	"Synthesis of PIPs at the Golgi membrane"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBT7"	"Alpha-catulin OS=Homo sapiens OX=9606 GN=CTNNAL1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"734"	"81.8"	"6.64"	"289.30"	"2.42"	"1"	"1"	"cell adhesion;signal transduction"	"plasma membrane;other membranes;cytosol;cytoskeleton"	"cytoskeletal activity;other molecular function"	"Pf01044"	"8727"	"ENSG00000119326"	"CTNNAL1"	"B5BU47; hsa:8727; O76084; Q53FQ2; Q5JTQ7; Q5JTQ8; Q9UBT7; Q9Y401"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q6IA86"	"Elongator complex protein 2 OS=Homo sapiens OX=9606 GN=ELP2 PE=1 SV=2"	"1"	"1"	"2"	"1"	"826"	"92.4"	"5.96"	"276.49"	"2.42"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00400"	"55250"	"ENSG00000134759"	"ELP2"	"A8KAI6; B4DTG0; B4DXP0; E7EP23; E9PCX0; hsa:55250; Q53GZ0; Q687Y8; Q6IA86; Q8N5C2; Q96GV4; Q96PI7; Q9H9N0; Q9NV81"	"HATs acetylate histones"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q6P1X6"	"UPF0598 protein C8orf82 OS=Homo sapiens OX=9606 GN=C8orf82 PE=1 SV=2"	"7"	"1"	"2"	"1"	"216"	"23.9"	"9.14"	"348.82"	"2.42"	"1"	"1"	""	""	""	"Pf14956"	"414919"	"ENSG00000213563"	"C8orf82"	"hsa:414919; Q6GMR2; Q6P1X6; Q6P2Q7"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60520"	"Gamma-aminobutyric acid receptor-associated protein-like 2 OS=Homo sapiens OX=9606 GN=GABARAPL2 PE=1 SV=1"	"7"	"1"	"2"	"1"	"117"	"13.7"	"8.10"	"367.88"	"2.42"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;stress response;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf02991"	"11345"	"ENSG00000034713"	"GABARAPL2"	"hsa:11345; O08765; P60520; Q6FG91; Q9DCP8; Q9UQF7"	"TBC/RABGAPs; Macroautophagy"	"Network map of SARS-CoV-2 signaling pathway; 2q37 copy number variation syndrome"	"4"	"0"	"71.3"	"81.2"	"206.8"	"51.0"	"59.6"	"60.2"	"302.5"	"37.5"	"55.2"	"95.6"	"241.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WX93"	"Palladin OS=Homo sapiens OX=9606 GN=PALLD PE=1 SV=3"	"1"	"1"	"1"	"1"	"1383"	"150.5"	"7.09"	""	"2.42"	""	"1"	"cell adhesion;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf07679"	"23022"	"ENSG00000129116"	"PALLD"	"B3KTG2; B5MD56; B7ZMM5; hsa:23022; Q7L3E0; Q7Z3W0; Q86WE8; Q8N1M2; Q8WX93; Q9UGA0; Q9UQF5; Q9Y2J6; Q9Y3E9"	""	""	"0"	"0"	"30.3"	"34.0"	"88.6"	"27.4"	"27.5"	"25.4"	"78.3"	"14.9"	"24.3"	"16.0"	"16.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P16083"	"Ribosyldihydronicotinamide dehydrogenase [quinone] OS=Homo sapiens OX=9606 GN=NQO2 PE=1 SV=5"	"9"	"1"	"1"	"1"	"231"	"25.9"	"6.29"	""	"2.42"	""	"1"	"other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf02525"	"4835"	"ENSG00000124588"	"NQO2"	"B2R492; hsa:4835; P16083; Q5TD04"	"Phase I - Functionalization of compounds"	"Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling"	"2"	"0"	"19.3"	"13.1"	"61.5"	"22.0"	"20.7"	"12.1"	"54.1"	"9.6"	"19.0"	"13.7"	"14.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P42696"	"RNA-binding protein 34 OS=Homo sapiens OX=9606 GN=RBM34 PE=1 SV=2"	"3"	"1"	"2"	"1"	"430"	"48.5"	"10.11"	"336.16"	"2.42"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"23029"	"ENSG00000188739"	"RBM34"	"A8K8J7; hsa:23029; P42696; Q8N2Z8; Q9H5A1"	""	""	"0"	"0"	"39.8"	"32.1"	"93.2"	"16.7"	"21.1"	"27.5"	"70.5"	"6.6"	"15.7"	"8.7"	"14.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NQ88"	"Fructose-2,6-bisphosphatase TIGAR OS=Homo sapiens OX=9606 GN=TIGAR PE=1 SV=1"	"4"	"1"	"1"	"1"	"270"	"30.0"	"7.69"	""	"2.41"	""	"1"	"cell organization and biogenesis;other metabolic processes;stress response;developmental processes;other biological processes"	"other membranes;cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00300"	"57103"	"ENSG00000078237"	"TIGAR"	"B2R840; hsa:57103; Q9NQ88"	"TP53 Regulates Metabolic Genes"	"Metabolic reprogramming in colon cancer; p53 transcriptional gene network"	"3"	"0"	"3.2"	"5.0"	"38.6"	"3.4"	"5.4"	"4.2"	"63.9"	"0.0"	"6.7"	"0.0"	"0.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9BY42"	"Replication termination factor 2 OS=Homo sapiens OX=9606 GN=RTF2 PE=1 SV=3"	"3"	"1"	"2"	"1"	"306"	"33.9"	"8.59"	"258.62"	"2.41"	"1"	"1"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf04641"	"51507"	"ENSG00000022277"	"RTF2"	"E1P5Z9; hsa:51507; Q9BY42; Q9BYL7; Q9HCV9; Q9NX29; Q9NZZ8; Q9P002; Q9UHW3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q2KHT3"	"Protein CLEC16A OS=Homo sapiens OX=9606 GN=CLEC16A PE=1 SV=2"	"1"	"1"	"2"	"1"	"1053"	"117.6"	"5.86"	"235.73"	"2.41"	"1"	"1"	"other metabolic processes;stress response;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf09758, Pf19439"	"23274"	"ENSG00000038532"	"CLEC16A"	"hsa:23274; O15058; Q2KHT3; Q6ZTB2"	""	"Vitamin D receptor pathway"	"1"	"0"	"147.1"	"134.5"	"484.8"	"126.9"	"75.8"	"71.1"	"363.8"	"80.2"	"91.3"	"82.3"	"100.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A6NKF1"	"SAC3 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SAC3D1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"404"	"43.5"	"8.69"	"287.88"	"2.41"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;nucleus;other cell component"	""	"Pf03399"	""	""	"SAC3D1"	"A6NKF1; A8MX08; Q99773"	""	""	"0"	"0"	"11.4"	"14.6"	"48.5"	"5.8"	"11.2"	"6.6"	"47.4"	"6.7"	"11.2"	"8.8"	"11.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EQ0"	"Small glutamine-rich tetratricopeptide repeat-containing protein beta OS=Homo sapiens OX=9606 GN=SGTB PE=1 SV=1"	"7"	"1"	"2"	"1"	"304"	"33.4"	"4.92"	"252.51"	"2.41"	"1"	"1"	"transport"	"other membranes;cytosol"	"other molecular function"	"Pf00515, Pf13414, Pf16546"	"54557"	"ENSG00000197860"	"SGTB"	"hsa:54557; Q96EQ0"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKV5"	"E3 ubiquitin-protein ligase AMFR OS=Homo sapiens OX=9606 GN=AMFR PE=1 SV=2"	"2"	"1"	"1"	"1"	"643"	"72.9"	"6.39"	""	"2.41"	""	"1"	"cell-cell signaling;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf02845, Pf13639, Pf18442"	"267"	"ENSG00000159461"	"AMFR"	"hsa:267; P26442; Q8IZ70; Q9UKV5"	"ER Quality Control Compartment (ERQC); N-glycan trimming in the ER and Calnexin/Calreticulin cycle"	"Sterol regulatory element-binding proteins (SREBP) signaling"	"3"	"0"	"11.6"	"24.7"	"33.2"	"16.4"	"20.7"	"23.3"	"19.5"	"12.7"	"23.1"	"42.0"	"59.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51397"	"Death-associated protein 1 OS=Homo sapiens OX=9606 GN=DAP PE=1 SV=3"	"8"	"1"	"1"	"1"	"102"	"11.2"	"9.32"	""	"2.41"	""	"1"	"other metabolic processes;stress response;signal transduction;other biological processes"	""	"other molecular function"	"Pf15228"	"1611"	"ENSG00000112977"	"DAP"	"hsa:1611; P51397; Q6FGC3; Q9BUC9"	""	""	"0"	"0"	"55.3"	"56.5"	"151.1"	"57.3"	"74.4"	"59.5"	"195.6"	"45.0"	"50.4"	"53.6"	"30.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75691"	"Small subunit processome component 20 homolog OS=Homo sapiens OX=9606 GN=UTP20 PE=1 SV=3"	"1"	"1"	"1"	"1"	"2785"	"318.2"	"7.39"	""	"2.40"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	""	"Pf07539, Pf20416"	"27340"	"ENSG00000120800"	"UTP20"	"hsa:27340; O75691; Q9H3H4"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	"61.2"	"54.6"	"290.1"	"84.5"	"73.9"	"65.1"	"245.5"	"17.0"	"39.5"	"29.7"	"24.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P54687"	"Branched-chain-amino-acid aminotransferase, cytosolic OS=Homo sapiens OX=9606 GN=BCAT1 PE=1 SV=3"	"3"	"1"	"2"	"1"	"386"	"42.9"	"5.30"	"265.54"	"2.40"	"1"	"1"	"cell cycle OR cell proliferation;other metabolic processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf01063"	"586"	"ENSG00000060982"	"BCAT1"	"B3KY27; B7Z2M5; B7Z5L0; F5H5E4; hsa:586; P54687; Q68DQ7; Q96MY9"	"Branched-chain amino acid catabolism"	"Trans-sulfuration, one-carbon metabolism and related pathways; Amino acid metabolism"	"3"	"0"	"18.6"	"24.5"	"70.5"	"16.9"	"12.9"	"8.9"	"80.3"	"8.9"	"18.7"	"8.1"	"7.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P53367"	"Arfaptin-1 OS=Homo sapiens OX=9606 GN=ARFIP1 PE=1 SV=2"	"3"	"1"	"2"	"1"	"373"	"41.7"	"6.70"	"291.35"	"2.40"	"1"	"1"	"transport;other biological processes"	"other membranes;cytosol;ER/Golgi"	"other molecular function"	"Pf06456"	"27236"	"ENSG00000164144"	"ARFIP1"	"B4DS69; hsa:27236; P53367; Q2M2X4; Q3SYL4; Q9Y2X6"	""	""	"0"	"0"	"22.7"	"26.3"	"88.7"	"18.1"	"22.6"	"12.1"	"70.1"	"6.3"	"10.6"	"5.9"	"7.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60566"	"Mitotic checkpoint serine/threonine-protein kinase BUB1 beta OS=Homo sapiens OX=9606 GN=BUB1B PE=1 SV=3"	"2"	"1"	"1"	"1"	"1050"	"119.5"	"5.27"	""	"2.40"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf08311"	"701"	"ENSG00000156970"	"BUB1B"	"B2R6U0; B4DL09; B4DLG3; hsa:701; O60501; O60566; O60627; O60758; O75389; Q59HH6; Q8WV50; Q96KM4"	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of mitotic proteins; APC-Cdc20 mediated degradation of Nek2A"	"Regulation of sister chromatid separation at the metaphase-anaphase transition"	"11"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q8IXB1"	"DnaJ homolog subfamily C member 10 OS=Homo sapiens OX=9606 GN=DNAJC10 PE=1 SV=2"	"1"	"1"	"2"	"1"	"793"	"91.0"	"7.18"	"267.58"	"2.39"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"ER/Golgi"	"other molecular function"	"Pf00085, Pf00226"	"54431"	"ENSG00000077232"	"DNAJC10"	"hsa:54431; Q17RJ6; Q3B7W8; Q4ZG06; Q53QT7; Q6UWZ6; Q86T61; Q8IXB1; Q8NC82; Q8TD87; Q96K38; Q96K44; Q96K54; Q9NSY6"	""	""	"0"	"0"	"14.4"	"14.4"	"28.4"	"10.1"	"10.7"	"7.9"	"20.9"	"2.9"	"5.3"	"3.9"	"5.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EH3"	"Mitochondrial assembly of ribosomal large subunit protein 1 OS=Homo sapiens OX=9606 GN=MALSU1 PE=1 SV=1"	"5"	"1"	"1"	"1"	"234"	"26.2"	"5.49"	""	"2.39"	""	"1"	"other biological processes"	"cytosol;mitochondrion"	"translation activity"	"Pf02410"	"115416"	"ENSG00000156928"	"MALSU1"	"A4D154; hsa:115416; Q96EH3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WVX9"	"Fatty acyl-CoA reductase 1 OS=Homo sapiens OX=9606 GN=FAR1 PE=1 SV=1"	"2"	"1"	"1"	"1"	"515"	"59.3"	"9.17"	""	"2.39"	""	"1"	"other metabolic processes"	"other membranes;other cytoplasmic organelle"	"other molecular function"	"Pf03015, Pf07993"	"84188"	"ENSG00000197601"	"FAR1"	"D3DQW8; hsa:84188; Q5CZA3; Q8WVX9"	"Wax biosynthesis"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q29RF7"	"Sister chromatid cohesion protein PDS5 homolog A OS=Homo sapiens OX=9606 GN=PDS5A PE=1 SV=1"	"1"	"1"	"2"	"1"	"1337"	"150.7"	"7.91"	"280.22"	"2.39"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	""	"Pf20168"	"23244"	"ENSG00000121892"	"PDS5A"	"hsa:23244; Q29RF7; Q2TTR5; Q68DF7; Q8N7J4; Q8NG14; Q9Y4D4"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"Cohesin complex - Cornelia de Lange syndrome"	"5"	"0"	"137.6"	"142.2"	"438.8"	"121.2"	"104.4"	"72.4"	"527.3"	"82.7"	"132.5"	"136.2"	"211.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TD19"	"Serine/threonine-protein kinase Nek9 OS=Homo sapiens OX=9606 GN=NEK9 PE=1 SV=2"	"1"	"1"	"1"	"1"	"979"	"107.1"	"5.74"	""	"2.39"	""	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069, Pf00415"	"91754"	"ENSG00000119638"	"NEK9"	"hsa:91754; Q52LK6; Q8NCN0; Q8TCY4; Q8TD19; Q9UPI4; Q9Y6S4; Q9Y6S5; Q9Y6S6"	"EML4 and NUDC in mitotic spindle formation; Nuclear Pore Complex (NPC) Disassembly; Activation of NIMA Kinases NEK9, NEK6, NEK7"	"Ciliopathies; 11p11.2 copy number variation syndrome"	"5"	"0"	"14.3"	"13.3"	"61.7"	"15.1"	"10.0"	"11.5"	"63.8"	"6.0"	"8.0"	"6.6"	"5.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43617"	"Trafficking protein particle complex subunit 3 OS=Homo sapiens OX=9606 GN=TRAPPC3 PE=1 SV=1"	"4"	"1"	"2"	"1"	"180"	"20.3"	"4.96"	"278.83"	"2.38"	"1"	"1"	"cell organization and biogenesis;transport"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf04051"	"27095"	"ENSG00000054116"	"TRAPPC3"	"A6NDN0; B2RDN2; D3DPS2; hsa:27095; O43617"	"RAB GEFs exchange GTP for GDP on RABs; COPII-mediated vesicle transport"	""	"2"	"0"	"51.4"	"54.7"	"269.4"	"59.7"	"42.0"	"46.0"	"241.5"	"27.8"	"36.8"	"36.8"	"48.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13564"	"NEDD8-activating enzyme E1 regulatory subunit OS=Homo sapiens OX=9606 GN=NAE1 PE=1 SV=1"	"1"	"1"	"1"	"1"	"534"	"60.2"	"5.40"	""	"2.38"	""	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00899"	"8883"	"ENSG00000159593"	"NAE1"	"A6NCK0; A6NFN4; A8MU28; B2R700; B3KUP9; hsa:8883; Q13564"	"Neddylation"	"Alzheimer's disease and miRNA effects; Hijack of ubiquitination by SARS-CoV-2; Alzheimer's disease"	"4"	"0"	"12.1"	"13.9"	"68.8"	"10.2"	"10.0"	"4.6"	"81.2"	"7.2"	"5.1"	"2.6"	"3.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14498"	"RNA-binding protein 39 OS=Homo sapiens OX=9606 GN=RBM39 PE=1 SV=2"	"4"	"2"	"3"	"2"	"530"	"59.3"	"10.10"	"518.45"	"2.38"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00076, Pf15519"	"9584"	"ENSG00000131051"	"RBM39"	"A2RRD3; A5D8W2; B0BLV3; E1P5S0; E1P5S1; hsa:9584; Q14498; Q14499"	"mRNA Splicing - Major Pathway"	"VEGFA-VEGFR2 signaling; mRNA processing"	"3"	"0"	"103.7"	"114.8"	"462.8"	"88.3"	"77.0"	"52.8"	"482.3"	"40.6"	"56.8"	"45.1"	"51.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75794"	"Cell division cycle protein 123 homolog OS=Homo sapiens OX=9606 GN=CDC123 PE=1 SV=1"	"2"	"1"	"2"	"1"	"336"	"39.1"	"4.81"	"251.47"	"2.38"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"other cell component"	""	"Pf07065"	"8872"	"ENSG00000151465"	"CDC123"	"A8JZZ7; hsa:8872; O75794; Q14107; Q5T0L4; Q5T0L5; Q5T0L7; Q5T0L8; Q5T0L9"	""	""	"0"	"0"	"95.9"	"111.7"	"415.0"	"104.6"	"78.3"	"78.0"	"440.3"	"90.5"	"137.0"	"170.9"	"266.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86W74"	"Ankyrin repeat domain-containing protein 46 OS=Homo sapiens OX=9606 GN=ANKRD46 PE=1 SV=1"	"5"	"1"	"2"	"1"	"232"	"26.0"	"7.15"	"245.98"	"2.38"	"1"	"1"	""	"other membranes"	""	"Pf12796"	"100969895; 157567"	"ENSPPAG00000028250; ENSPTRG00000020473"	"ANKRD46"	"A0A024R9G2; A0A2I3TGT7; A0A2J8PMF6; A0A2R9A429; A0A6D2XEW4"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"P42773"	"Cyclin-dependent kinase 4 inhibitor C OS=Homo sapiens OX=9606 GN=CDKN2C PE=1 SV=1"	"4"	"1"	"2"	"1"	"168"	"18.1"	"6.52"	"283.91"	"2.37"	"1"	"1"	"cell cycle OR cell proliferation;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf13637"	"1031"	"ENSG00000123080"	"CDKN2C"	"hsa:1031; P42773; Q8TB83"	"Oxidative Stress Induced Senescence; Oncogene Induced Senescence; Cyclin D associated events in G1; Senescence-Associated Secretory Phenotype (SASP)"	"Cell cycle; Glioblastoma signaling pathways; Vitamin D receptor pathway; G1 to S cell cycle control"	"8"	"0"	"36.6"	"51.9"	"230.0"	"62.5"	"55.4"	"56.1"	"305.0"	"30.0"	"49.2"	"45.1"	"49.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N5L8"	"Ribonuclease P protein subunit p25-like protein OS=Homo sapiens OX=9606 GN=RPP25L PE=1 SV=1"	"6"	"1"	"2"	"1"	"163"	"17.6"	"10.30"	"276.94"	"2.37"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf01918"	"138716"	"ENSG00000164967"	"RPP25L"	"D3DRM5; hsa:138716; Q8N5L8"	""	""	"0"	"0"	"26.5"	"43.8"	"156.5"	"45.3"	"27.0"	"32.4"	"143.6"	"23.5"	"30.1"	"24.2"	"25.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99627"	"COP9 signalosome complex subunit 8 OS=Homo sapiens OX=9606 GN=COPS8 PE=1 SV=1"	"11"	"2"	"2"	"2"	"209"	"23.2"	"5.38"	"630.38"	"2.37"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf10075"	"10920"	"ENSG00000198612"	"COPS8"	"A8K1H6; hsa:10920; Q53QS9; Q99627"	"DNA Damage Recognition in GG-NER; Cargo recognition for clathrin-mediated endocytosis; Neddylation; Formation of TC-NER Pre-Incision Complex"	"Ciliary landscape; 2q37 copy number variation syndrome"	"6"	"0"	"179.3"	"212.0"	"660.9"	"202.7"	"195.3"	"154.3"	"946.4"	"179.3"	"246.4"	"173.6"	"184.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96P16"	"Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1"	"4"	"1"	"2"	"1"	"312"	"35.7"	"7.55"	"291.61"	"2.37"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf04818, Pf16566"	"55197"	"ENSG00000141425"	"RPRD1A"	"A8KA42; B2RBA3; hsa:55197; Q7Z5G8; Q96FY9; Q96P16; Q9NVL4"	"RNA polymerase II transcribes snRNA genes"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62873"	"Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 OS=Homo sapiens OX=9606 GN=GNB1 PE=1 SV=3"	"3"	"1"	"1"	"1"	"340"	"37.4"	"6.00"	""	"2.37"	""	"1"	"cell-cell signaling;cell cycle OR cell proliferation;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00400"	"2782"	"ENSG00000078369"	"GNB1"	"B1AJZ7; hsa:2782; P04697; P04901; P62873; Q1RMY8"	"G alpha (q) signalling events; Thrombin signalling through proteinase activated receptors (PARs); G alpha (12/13) signalling events; Olfactory Signaling Pathway; G alpha (i) signalling events; G alpha (z) signalling events; Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1); ADP signalling through P2Y purinoceptor 12; Extra-nuclear estrogen signaling; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production; Sensory perception of sweet, bitter, and umami (glutamate) taste; Activation of G protein gated Potassium channels; G-protein activation; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; G beta:gamma signalling through PI3Kgamma; Prostacyclin signalling through prostacyclin receptor; Adrenaline,noradrenaline inhibits insulin secretion; Ca2+ pathway; G beta:gamma signalling through PLC beta; ADP signalling through P2Y purinoceptor 1; Glucagon-type ligand receptors; Thromboxane signalling through TP receptor; Vasopressin regulates renal water homeostasis via Aquaporins; Presynaptic function of Kainate receptors; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; G beta:gamma signalling through BTK; G beta:gamma signalling through CDC42; Inhibition  of voltage gated Ca2+ channels via Gbeta/gamma subunits; Inactivation, recovery and regulation of the phototransduction cascade; Glucagon signaling in metabolic regulation; Activation of the phototransduction cascade"	"Nicotine effect on dopaminergic neurons; Thyroid stimulating hormone (TSH) signaling pathway; Corticotropin-releasing hormone signaling pathway; Myometrial relaxation and contraction pathways; G protein signaling pathways; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Ras signaling; 1p36 copy number variation syndrome; 11p11.2 copy number variation syndrome ; Calcium regulation in cardiac cells; Estrogen signaling pathway"	"46"	"0"	"29.0"	"35.5"	"120.6"	"39.0"	"38.7"	"29.7"	"114.8"	"17.8"	"27.9"	"20.7"	"18.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BUQ8"	"Probable ATP-dependent RNA helicase DDX23 OS=Homo sapiens OX=9606 GN=DDX23 PE=1 SV=3"	"1"	"1"	"2"	"1"	"820"	"95.5"	"9.55"	"310.58"	"2.36"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271"	"9416"	"ENSG00000174243"	"DDX23"	"B2R600; B4DH15; hsa:9416; O43188; Q9BUQ8"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	""	"2"	"0"	"13.7"	"16.7"	"97.6"	"16.2"	"13.5"	"8.0"	"138.4"	"4.2"	"10.3"	"7.9"	"10.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IZH2"	"5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1"	"1"	"1"	"1"	"1"	"1706"	"194.0"	"7.21"	""	"2.36"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03159, Pf17846, Pf18129, Pf18332, Pf18334"	"54464"	"ENSG00000114127"	"XRN1"	"hsa:54464; Q4G0S3; Q68D88; Q6AI24; Q6MZS8; Q86WS7; Q8IZH2; Q8N8U4; Q9UF39"	"mRNA decay by 5' to 3' exoribonuclease; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"	"miRNA degrading enzymes"	"4"	"0"	"13.8"	"12.1"	"33.9"	"13.8"	"14.5"	"13.1"	"39.9"	"6.6"	"9.1"	"14.0"	"12.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O96013"	"Serine/threonine-protein kinase PAK 4 OS=Homo sapiens OX=9606 GN=PAK4 PE=1 SV=1"	"2"	"1"	"1"	"1"	"591"	"64.0"	"9.73"	""	"2.36"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;ER/Golgi;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00786"	"10298"	"ENSG00000130669"	"PAK4"	"B4DGG6; hsa:10298; O96013; Q8N4E1; Q8NCH5; Q8NDE3; Q9BU33; Q9ULS8"	"RHOG GTPase cycle; RAC2 GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RAC3 GTPase cycle; RHOJ GTPase cycle; RHOV GTPase cycle; RHOU GTPase cycle; Activation of RAC1; RHOH GTPase cycle"	"Integrin-mediated cell adhesion; Focal adhesion; Ras signaling; Pancreatic adenocarcinoma pathway; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-Merlin signaling dysregulation; Neural crest cell migration during development; Neural crest cell migration in cancer; 22q11.2 copy number variation syndrome; Pleural mesothelioma; Regulation of actin cytoskeleton; TROP2 regulatory signaling; ErbB signaling pathway"	"24"	"0"	"73.9"	"80.4"	"227.7"	"57.6"	"66.3"	"52.6"	"244.1"	"44.9"	"56.0"	"67.4"	"58.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P29372"	"DNA-3-methyladenine glycosylase OS=Homo sapiens OX=9606 GN=MPG PE=1 SV=3"	"3"	"1"	"2"	"1"	"298"	"32.8"	"9.57"	"322.36"	"2.36"	"1"	"1"	"DNA metabolism;other metabolic processes;stress response"	"cytosol;mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf02245"	"4350"	"ENSG00000103152"	"MPG"	"G5E9E2; hsa:4350; P29372; Q13770; Q15275; Q15961; Q5J9I4; Q96BZ6; Q96S33; Q9NNX5"	"Recognition and association of DNA glycosylase with site containing an affected purine; Cleavage of the damaged purine; Displacement of DNA glycosylase by APEX1"	"Base excision repair; DNA repair pathways, full network"	"5"	"0"	"78.4"	"88.6"	"229.4"	"87.2"	"80.3"	"62.2"	"359.3"	"106.5"	"139.1"	"123.6"	"138.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BXW9"	"Fanconi anemia group D2 protein OS=Homo sapiens OX=9606 GN=FANCD2 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1451"	"164.0"	"5.88"	"239.15"	"2.36"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf14631"	"2177"	"ENSG00000144554"	"FANCD2"	"hsa:2177; Q2LA86; Q69YP9; Q6PJN7; Q9BQ06; Q9BXW9; Q9H9T9"	"Fanconi Anemia Pathway; TP53 Regulates Transcription of DNA Repair Genes"	"miRNA regulation of DNA damage response; 15q13.3 copy number variation syndrome; DNA repair pathways, full network; DNA damage response"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q68CQ4"	"Digestive organ expansion factor homolog OS=Homo sapiens OX=9606 GN=DIEXF PE=1 SV=2"	"1"	"1"	"1"	"1"	"756"	"87.0"	"5.88"	""	"2.36"	""	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf06862"	"27042"	"ENSG00000117597"	"UTP25"	"hsa:27042; O75992; Q4VY00; Q63HL9; Q68CQ4"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NTI5"	"Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens OX=9606 GN=PDS5B PE=1 SV=1"	"1"	"1"	"2"	"1"	"1447"	"164.6"	"8.47"	"256.08"	"2.36"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf20168"	"23047"	"ENSG00000083642"	"PDS5B"	"hsa:23047; Q5R3S3; Q5W0K8; Q6NSC3; Q8IXT6; Q9H5N8; Q9NTI5; Q9Y2I5; Q9Y451"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"Cohesin complex - Cornelia de Lange syndrome"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9NVM9"	"Integrator complex subunit 13 OS=Homo sapiens OX=9606 GN=INTS13 PE=1 SV=2"	"3"	"2"	"3"	"2"	"706"	"80.2"	"6.70"	"672.08"	"2.35"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf10221"	"55726"	"ENSG00000064102"	"INTS13"	"B4DNK1; hsa:55726; Q86WE2; Q96HM2; Q9BTX2; Q9NTB6; Q9NVM5; Q9NVM9"	"RNA polymerase II transcribes snRNA genes"	"1p36 copy number variation syndrome"	"2"	"0"	"57.5"	"61.5"	"173.0"	"58.5"	"65.1"	"50.1"	"195.9"	"31.5"	"56.3"	"54.8"	"65.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UJT1"	"Tubulin delta chain OS=Homo sapiens OX=9606 GN=TUBD1 PE=2 SV=2"	"3"	"1"	"1"	"1"	"453"	"51.0"	"6.83"	""	"2.35"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00091"	"51174"	"ENSG00000108423"	"TUBD1"	"B4DPT8; B4DW01; D3DU02; E9PCA7; E9PCQ8; hsa:51174; Q5KU36; Q9BWG9; Q9H7Z8; Q9UJT1"	""	"Genes related to primary cilium development (based on CRISPR)"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9P035"	"Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 OS=Homo sapiens OX=9606 GN=HACD3 PE=1 SV=2"	"2"	"1"	"1"	"1"	"362"	"43.1"	"8.94"	""	"2.35"	""	"1"	"other metabolic processes;stress response;signal transduction;other biological processes"	"other membranes;ER/Golgi;nucleus"	"enzyme regulator activity;other molecular function"	"Pf04387"	"51495"	"ENSG00000074696"	"HACD3"	"A0PJA1; B4DRF4; hsa:51495; Q280Z3; Q6PD63; Q8IUI5; Q8NC86; Q8NCB1; Q96T12; Q9NQA7; Q9P035"	"Synthesis of very long-chain fatty acyl-CoAs"	""	"1"	"0"	"183.7"	"198.3"	"626.5"	"170.5"	"144.7"	"127.2"	"579.8"	"65.7"	"104.4"	"90.7"	"88.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96G46"	"tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like OS=Homo sapiens OX=9606 GN=DUS3L PE=1 SV=2"	"2"	"1"	"1"	"1"	"650"	"72.5"	"8.05"	""	"2.35"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	""	"other molecular function"	"Pf01207, Pf18044"	"56931"	"ENSG00000141994"	"DUS3L"	"hsa:56931; Q96G46; Q96HM5; Q9BSU4; Q9H877; Q9NPR1"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q6ZXV5"	"Protein O-mannosyl-transferase TMTC3 OS=Homo sapiens OX=9606 GN=TMTC3 PE=1 SV=2"	"1"	"1"	"3"	"1"	"915"	"103.9"	"8.87"	"676.75"	"2.34"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf08409, Pf13174, Pf13181, Pf13431"	"160418"	"ENSG00000139324"	"TMTC3"	"hsa:160418; Q5CZ86; Q5H9T6; Q68DQ6; Q68DX0; Q6ZXV5; Q7Z332; Q8NC50"	""	""	"0"	"0"	"22.0"	"18.8"	"72.6"	"15.3"	"12.4"	"11.2"	"47.7"	"4.0"	"7.2"	"5.4"	"5.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UL16"	"Cilia- and flagella-associated protein 45 OS=Homo sapiens OX=9606 GN=CFAP45 PE=1 SV=2"	"1"	"1"	"1"	"1"	"551"	"65.7"	"8.90"	""	"2.34"	""	"1"	"transport;developmental processes;other biological processes"	"non-structural extracellular;cytoskeleton;nucleus"	"other molecular function"	"Pf13868"	"25790"	"ENSG00000213085"	"CFAP45"	"C9JH28; hsa:25790; Q05BA3; Q5VU18; Q9UL16"	""	""	"0"	"0"	"35.7"	"46.0"	"184.2"	"56.6"	"53.0"	"35.7"	"594.9"	"104.0"	"104.1"	"71.7"	"78.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9ULV4"	"Coronin-1C OS=Homo sapiens OX=9606 GN=CORO1C PE=1 SV=1"	"1"	"1"	"2"	"1"	"474"	"53.2"	"7.08"	"247.10"	"2.34"	"1"	"1"	"cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400, Pf08953, Pf16300"	"23603"	"ENSG00000110880"	"CORO1C"	"A7MAP0; A7MAP1; B3KU12; hsa:23603; Q9NSK5; Q9ULV4"	""	""	"0"	"0"	"113.1"	"117.5"	"446.7"	"119.4"	"106.0"	"94.3"	"295.5"	"58.6"	"82.1"	"82.8"	"52.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NHQ9"	"ATP-dependent RNA helicase DDX55 OS=Homo sapiens OX=9606 GN=DDX55 PE=1 SV=3"	"4"	"2"	"3"	"2"	"600"	"68.5"	"9.25"	"596.37"	"2.34"	"2"	"1"	""	"cytosol;nucleus"	"other molecular function"	"Pf00270, Pf00271, Pf13959"	"57696"	"ENSG00000111364"	"DDX55"	"hsa:57696; Q658L6; Q8IYH0; Q8NHQ9; Q9HCH7"	""	""	"0"	"0"	"11.6"	"11.6"	"37.3"	"8.0"	"10.9"	"7.1"	"65.4"	"2.3"	"8.1"	"6.2"	"6.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H1A4"	"Anaphase-promoting complex subunit 1 OS=Homo sapiens OX=9606 GN=ANAPC1 PE=1 SV=1"	"0"	"1"	"2"	"1"	"1944"	"216.4"	"6.30"	"319.81"	"2.33"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf12859, Pf18122, Pf19521, Pf20518"	"64682"	"ENSG00000153107"	"ANAPC1"	"hsa:64682; Q2M3H8; Q9BSE6; Q9H1A4; Q9H8D0"	"Separation of Sister Chromatids; Antigen processing: Ubiquitination & Proteasome degradation; Senescence-Associated Secretory Phenotype (SASP); APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; CDK-mediated phosphorylation and removal of Cdc6; Autodegradation of Cdh1 by Cdh1:APC/C; Assembly of the pre-replicative complex; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of Cyclin B; Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase; Regulation of APC/C activators between G1/S and early anaphase; Phosphorylation of the APC/C; APC-Cdc20 mediated degradation of Nek2A; Transcriptional Regulation by VENTX; Aberrant regulation of mitotic exit in cancer due to RB1 defects"	"Cell cycle; 2q13 copy number variation syndrome"	"20"	"0"	"33.9"	"37.0"	"108.6"	"28.7"	"30.2"	"24.8"	"103.2"	"15.2"	"17.6"	"15.2"	"11.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96S52"	"GPI transamidase component PIG-S OS=Homo sapiens OX=9606 GN=PIGS PE=1 SV=3"	"2"	"1"	"2"	"1"	"555"	"61.6"	"6.49"	"270.47"	"2.33"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;ER/Golgi"	""	"Pf10510"	"94005"	"ENSG00000087111"	"PIGS"	"hsa:94005; Q6UVX6; Q96S52"	"Attachment of GPI anchor to uPAR"	""	"1"	"0"	"12.6"	"15.0"	"61.2"	"11.9"	"10.0"	"7.8"	"46.3"	"5.2"	"7.2"	"3.9"	"4.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8ND04"	"Protein SMG8 OS=Homo sapiens OX=9606 GN=SMG8 PE=1 SV=1"	"1"	"1"	"1"	"1"	"991"	"109.6"	"7.68"	""	"2.33"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol"	""	"Pf10220"	"55181"	"ENSG00000167447"	"SMG8"	"hsa:55181; Q8N5U5; Q8ND04; Q8TDN0; Q9H5P5; Q9NVQ1"	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q86VF2"	"Immunoglobulin-like and fibronectin type III domain-containing protein 1 OS=Homo sapiens OX=9606 GN=IGFN1 PE=1 SV=2"	"1"	"1"	"1"	"1"	"1251"	"137.7"	"7.56"	""	"2.33"	""	"1"	""	"cytoskeleton;nucleus"	""	"Pf00041, Pf07679, Pf18362"	"91156"	"ENSG00000163395"	"IGFN1"	"F8WAI1; hsa:91156; Q86VF2; Q9NT72"	""	""	"0"	"0"	"345.8"	"451.8"	"1299.1"	"437.8"	"430.9"	"324.2"	"1088.0"	"178.9"	"328.8"	"167.0"	"202.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q10570"	"Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1443"	"160.8"	"6.40"	"319.14"	"2.33"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03178, Pf10433"	"29894"	"ENSG00000071894; ENSG00000285049"	"CPSF1"	"hsa:29894; Q10570; Q96AF0"	"Transport of Mature mRNA Derived from an Intronless Transcript; tRNA processing in the nucleus; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"mRNA processing"	"7"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16222"	"UDP-N-acetylhexosamine pyrophosphorylase OS=Homo sapiens OX=9606 GN=UAP1 PE=1 SV=3"	"2"	"1"	"2"	"1"	"522"	"58.7"	"6.33"	"244.28"	"2.32"	"1"	"1"	"other metabolic processes"	"plasma membrane;other membranes;cytosol;nucleus"	"other molecular function"	"Pf01704"	"6675"	"ENSG00000117143"	"UAP1"	"B2R6R8; hsa:6675; Q16222; Q5VTA9; Q5VTB0; Q5VTB1; Q96GM2"	"Synthesis of UDP-N-acetyl-glucosamine"	""	"1"	"0"	"3.0"	"7.6"	"37.5"	"5.2"	"4.1"	"2.4"	"72.1"	"4.0"	"0.0"	"2.5"	"0.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9BUK6"	"Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1"	"4"	"2"	"4"	"2"	"570"	"61.8"	"6.11"	"547.91"	"2.32"	"2"	"2"	"cell organization and biogenesis"	"other membranes;cytosol;mitochondrion;other cell component"	""	"Pf10644, Pf14881"	"55154"	"ENSG00000125459"	"MSTO1"	"hsa:55154; Q53GR8; Q5CZ69; Q5T717; Q68CT6; Q7LBZ8; Q7Z3M7; Q7Z558; Q8TE05; Q9BUK6; Q9NQX2; Q9NVU4"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13610"	"Periodic tryptophan protein 1 homolog OS=Homo sapiens OX=9606 GN=PWP1 PE=1 SV=1"	"2"	"1"	"2"	"1"	"501"	"55.8"	"4.77"	"253.91"	"2.32"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00400"	"11137"	"ENSG00000136045"	"PWP1"	"A8K3R6; hsa:11137; Q13610; Q7Z3X9"	""	""	"0"	"0"	"130.2"	"129.0"	"381.6"	"131.5"	"121.2"	"117.6"	"398.8"	"55.0"	"123.9"	"73.3"	"81.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q567U6"	"Coiled-coil domain-containing protein 93 OS=Homo sapiens OX=9606 GN=CCDC93 PE=1 SV=2"	"2"	"1"	"2"	"1"	"631"	"73.2"	"8.15"	"302.27"	"2.32"	"1"	"1"	"transport"	"other cytoplasmic organelle;other cell component"	""	"Pf09762"	"54520"	"ENSG00000125633"	"CCDC93"	"A8K3V7; hsa:54520; Q4LE78; Q53TJ2; Q567U6; Q8TBX5; Q9H6R5; Q9NV15"	""	""	"0"	"0"	"9.5"	"11.1"	"42.0"	"13.7"	"7.5"	"9.6"	"32.7"	"4.5"	"11.0"	"7.7"	"6.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75340"	"Programmed cell death protein 6 OS=Homo sapiens OX=9606 GN=PDCD6 PE=1 SV=1"	"6"	"1"	"2"	"1"	"191"	"21.9"	"5.40"	"293.77"	"2.32"	"1"	"1"	"cell organization and biogenesis;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf13202, Pf13499"	"10016"	"ENSG00000249915"	"PDCD6"	"B2RD16; E7ESR3; hsa:10016; O75340; Q2YDC2; Q5TZS0"	""	"Epithelial to mesenchymal transition in colorectal cancer"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NRX2"	"39S ribosomal protein L17, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL17 PE=1 SV=1"	"5"	"1"	"2"	"1"	"175"	"20.0"	"10.11"	"265.22"	"2.32"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf01196"	"63875"	"ENSG00000158042"	"MRPL17"	"D3DQU3; hsa:63875; Q6IAH8; Q96Q53; Q9C066; Q9NRX2"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"61.9"	"77.8"	"219.3"	"65.7"	"56.9"	"52.0"	"267.2"	"32.4"	"44.5"	"38.9"	"40.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q93050"	"V-type proton ATPase 116 kDa subunit a isoform 1 OS=Homo sapiens OX=9606 GN=ATP6V0A1 PE=1 SV=3"	"1"	"1"	"2"	"1"	"837"	"96.4"	"6.43"	"242.17"	"2.32"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf01496"	"535"	"ENSG00000033627"	"ATP6V0A1"	"B7Z3B7; hsa:535; Q8N5G7; Q93050; Q9NSX0"	"Transferrin endocytosis and recycling; Neutrophil degranulation; ROS and RNS production in phagocytes; Insulin receptor recycling; Ion channel transport"	""	"5"	"0"	"9.7"	"7.2"	"43.2"	"8.6"	"7.2"	"3.9"	"38.7"	"3.7"	"2.6"	"0.0"	"3.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5T440"	"Putative transferase CAF17, mitochondrial OS=Homo sapiens OX=9606 GN=IBA57 PE=1 SV=1"	"3"	"1"	"1"	"1"	"356"	"38.1"	"9.83"	""	"2.32"	""	"1"	"cell organization and biogenesis;other metabolic processes"	"mitochondrion"	"other molecular function"	""	"200205"	"ENSG00000181873"	"IBA57"	"hsa:200205; Q5T440"	""	""	"0"	"0"	"86.6"	"60.0"	"229.7"	"68.5"	"61.2"	"58.6"	"342.7"	"107.1"	"141.1"	"126.3"	"157.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43148"	"mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1"	"2"	"1"	"2"	"1"	"476"	"54.8"	"6.61"	"334.58"	"2.32"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03291"	"8731"	"ENSG00000101654"	"RNMT"	"B0YJ90; D3DUJ5; hsa:8731; O43148; O94996; Q9UIJ9"	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE"	"mRNA processing"	"4"	"0"	"6.7"	"8.7"	"33.2"	"11.3"	"7.5"	"7.5"	"38.7"	"2.5"	"6.3"	"6.5"	"6.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P032"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 OS=Homo sapiens OX=9606 GN=NDUFAF4 PE=1 SV=1"	"3"	"1"	"2"	"1"	"175"	"20.3"	"8.82"	"249.47"	"2.32"	"1"	"1"	"cell organization and biogenesis;stress response;other biological processes"	"other membranes;cytosol;mitochondrion"	"other molecular function"	"Pf06784"	"29078"	"ENSG00000123545"	"NDUFAF4"	"B2R4J5; hsa:29078; Q9P032"	"Complex I biogenesis"	""	"1"	"0"	"165.8"	"198.2"	"887.8"	"149.3"	"96.3"	"80.9"	"974.8"	"59.7"	"83.5"	"53.1"	"45.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82914"	"28S ribosomal protein S15, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS15 PE=1 SV=1"	"3"	"1"	"2"	"1"	"257"	"29.8"	"10.48"	"309.26"	"2.31"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf00312"	"64960"	"ENSG00000116898"	"MRPS15"	"B2RD82; hsa:64960; P82914; Q9H2K1"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"187.7"	"219.4"	"654.9"	"226.0"	"174.0"	"159.6"	"615.7"	"75.4"	"89.9"	"75.4"	"97.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NBF2"	"NHL repeat-containing protein 2 OS=Homo sapiens OX=9606 GN=NHLRC2 PE=1 SV=1"	"1"	"1"	"2"	"1"	"726"	"79.4"	"5.55"	"269.65"	"2.31"	"1"	"1"	""	"non-structural extracellular;cytosol;other cell component"	""	"Pf01436, Pf13905"	"374354"	"ENSG00000196865"	"NHLRC2"	"hsa:374354; Q8N1H1; Q8N5A6; Q8NBF2"	"Platelet degranulation"	""	"1"	"0"	"26.2"	"38.2"	"175.4"	"35.7"	"31.3"	"27.4"	"218.4"	"26.2"	"31.7"	"16.6"	"20.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q969E8"	"Pre-rRNA-processing protein TSR2 homolog OS=Homo sapiens OX=9606 GN=TSR2 PE=1 SV=1"	"4"	"1"	"2"	"1"	"191"	"20.9"	"4.39"	"290.18"	"2.31"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf10273"	"90121"	"ENSG00000158526"	"TSR2"	"hsa:90121; Q969E8"	""	""	"0"	"0"	"30.8"	"44.1"	"187.0"	"37.8"	"29.8"	"36.7"	"226.8"	"28.6"	"38.7"	"24.6"	"32.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00471"	"Exocyst complex component 5 OS=Homo sapiens OX=9606 GN=EXOC5 PE=1 SV=1"	"2"	"1"	"1"	"1"	"708"	"81.8"	"6.71"	""	"2.31"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf07393"	"10640"	"ENSG00000070367"	"EXOC5"	"B2R6C5; hsa:10640; O00471; Q8IW24"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"Ciliary landscape"	"4"	"0"	"7.7"	"9.8"	"28.9"	"7.8"	"7.0"	"5.5"	"26.8"	"7.1"	"18.2"	"24.0"	"20.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HC35"	"Echinoderm microtubule-associated protein-like 4 OS=Homo sapiens OX=9606 GN=EML4 PE=1 SV=3"	"1"	"1"	"2"	"1"	"981"	"108.8"	"6.40"	"305.07"	"2.31"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400, Pf03451, Pf07714"	"27436"	"ENSG00000143924"	"EML4"	"A6H8Y6; A6P4T4; A6P4V4; B2RBK3; B2RTW7; B5MCW9; hsa:27436; Q3SWW0; Q53R29; Q53TW8; Q6PJ45; Q9HC35; Q9NV40"	"EML4 and NUDC in mitotic spindle formation; ALK mutants bind TKIs; Nuclear events stimulated by ALK signaling in cancer"	"Non-small cell lung cancer"	"5"	"0"	"40.8"	"48.4"	"179.5"	"34.6"	"28.2"	"25.2"	"205.4"	"31.3"	"36.8"	"19.5"	"27.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75764"	"Transcription elongation factor A protein 3 OS=Homo sapiens OX=9606 GN=TCEA3 PE=1 SV=2"	"4"	"1"	"1"	"1"	"348"	"38.9"	"9.19"	""	"2.31"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01096, Pf07500, Pf08711"	"6920"	"ENSG00000204219; ENSG00000282941"	"TCEA3"	"A8K2K7; hsa:6920; O75764; Q5DR83"	""	""	"0"	"0"	"49.6"	"75.5"	"201.0"	"68.2"	"73.6"	"65.4"	"183.5"	"46.4"	"78.3"	"69.2"	"86.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q969P5"	"F-box only protein 32 OS=Homo sapiens OX=9606 GN=FBXO32 PE=1 SV=1"	"3"	"1"	"1"	"1"	"355"	"41.6"	"9.36"	""	"2.31"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	""	""	"114907"	"ENSG00000156804"	"FBXO32"	"A4KYM0; hsa:114907; Q969P5"	"Antigen processing: Ubiquitination & Proteasome degradation; Neddylation; FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"	"Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; Pathophysiological roles of DUX4 in FSHD1; Monoamine transport"	"6"	"0"	"58.2"	"74.4"	"263.4"	"76.4"	"61.5"	"54.3"	"380.5"	"48.7"	"88.0"	"64.9"	"58.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92614"	"Unconventional myosin-XVIIIa OS=Homo sapiens OX=9606 GN=MYO18A PE=1 SV=3"	"1"	"2"	"3"	"2"	"2054"	"233.0"	"6.30"	"578.40"	"2.30"	"2"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00063, Pf01576, Pf17820"	"399687"	"ENSG00000196535"	"MYO18A"	"hsa:399687; Q5H9U3; Q5QD01; Q5W9F9; Q5W9G1; Q8IXP8; Q92614"	"Signaling by cytosolic FGFR1 fusion mutants; Signaling by FGFR1 in disease; Signaling by FLT3 fusion proteins"	""	"3"	"0"	"37.7"	"37.2"	"106.0"	"36.0"	"27.8"	"26.6"	"109.8"	"22.2"	"22.9"	"28.5"	"25.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UEG4"	"Zinc finger protein 629 OS=Homo sapiens OX=9606 GN=ZNF629 PE=1 SV=2"	"1"	"1"	"1"	"1"	"869"	"96.6"	"7.93"	""	"2.30"	""	"1"	"RNA metabolism OR transcription"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00096"	"23361"	"ENSG00000102870"	"ZNF629"	"hsa:23361; Q15938; Q9UEG4"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4X5"	"E3 ubiquitin-protein ligase ARIH1 OS=Homo sapiens OX=9606 GN=ARIH1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"557"	"64.1"	"5.08"	"239.03"	"2.30"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01485, Pf19422"	"25820"	"ENSG00000166233"	"ARIH1"	"B2R6U3; hsa:25820; O76026; Q9H3T6; Q9UEN0; Q9UP39; Q9Y4X5"	"ISG15 antiviral mechanism"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75844"	"CAAX prenyl protease 1 homolog OS=Homo sapiens OX=9606 GN=ZMPSTE24 PE=1 SV=2"	"3"	"1"	"1"	"1"	"475"	"54.8"	"7.49"	""	"2.30"	""	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01435, Pf16491"	"10269"	"ENSG00000084073"	"ZMPSTE24"	"B3KQI7; D3DPU7; hsa:10269; O75844; Q8NDZ8; Q9UBQ2"	""	"Adipogenesis; Lamin A-processing pathway; Nephrotic syndrome; Influence of laminopathies on Wnt signaling; Overlap between signal transduction pathways contributing to LMNA laminopathies; Familial partial lipodystrophy; Progeria-associated lipodystrophy"	"7"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"O00422"	"Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1"	"5"	"1"	"2"	"1"	"153"	"17.6"	"9.35"	"314.65"	"2.30"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf06487"	"10284"	"ENSG00000150459"	"SAP18"	"B2R494; hsa:10284; O00422; Q2TTR4; Q6IAW9; Q8N606; Q9UF14; X6RAL5"	"Potential therapeutics for SARS; HDACs deacetylate histones; NoRC negatively regulates rRNA expression; mRNA Splicing - Major Pathway"	"Hedgehog signaling pathway"	"5"	"0"	"154.3"	"150.5"	"553.5"	"123.4"	"118.1"	"84.9"	"629.2"	"71.2"	"105.6"	"92.7"	"93.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16539"	"Mitogen-activated protein kinase 14 OS=Homo sapiens OX=9606 GN=MAPK14 PE=1 SV=3"	"4"	"1"	"2"	"1"	"360"	"41.3"	"5.78"	"314.58"	"2.29"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"1432"	"ENSG00000112062"	"MAPK14"	"A6ZJ92; A8K6P4; B0LPH0; B5TY32; hsa:1432; O60776; Q13083; Q14084; Q16539; Q8TDX0"	"Neutrophil degranulation; p38MAPK events; ERK/MAPK targets; Platelet sensitization by LDL; Oxidative Stress Induced Senescence; Regulation of TP53 Activity through Phosphorylation; VEGFA-VEGFR2 Pathway; Myogenesis; ADP signalling through P2Y purinoceptor 1; NOD1/2 Signaling Pathway; DSCAM interactions; activated TAK1 mediates p38 MAPK activation; Activation of PPARGC1A (PGC-1alpha) by phosphorylation; KSRP (KHSRP) binds and destabilizes mRNA; Activation of the AP-1 family of transcription factors; RHO GTPases Activate NADPH Oxidases; CD163 mediating an anti-inflammatory response"	"Physiological and pathological hypertrophy of the heart; Angiogenesis; Energy metabolism; MicroRNAs in cardiomyocyte hypertrophy; IL-1 signaling pathway; RANKL/RANK signaling pathway; Thyroid stimulating hormone (TSH) signaling pathway; Leptin signaling pathway; Follicle stimulating hormone (FSH) signaling pathway; TNF-related weak inducer of apoptosis (TWEAK) signaling pathway; Prolactin signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; Androgen receptor network in prostate cancer; B cell receptor signaling pathway; AGE/RAGE pathway; Corticotropin-releasing hormone signaling pathway; Parkinson's disease pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Cardiac progenitor differentiation; Alpha 6 beta 4 signaling pathway; Amyotrophic lateral sclerosis (ALS); Interleukin-1 (IL-1) structural pathway; Cardiac hypertrophic response; Kit receptor signaling pathway; RAC1/PAK1/p38/MMP2 pathway; Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling; Hepatitis C and hepatocellular carcinoma; Hypothesized pathways in pathogenesis of cardiovascular disease; MAPK signaling pathway; Novel intracellular components of RIG-I-like receptor pathway; Canonical and non-canonical TGF-B signaling; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; IL-4 signaling pathway; p38 MAPK signaling pathway; Oxidative stress response; MAPK cascade; Epithelial to mesenchymal transition in colorectal cancer; Thermogenesis; miRNA role in immune response in sepsis; Non-genomic actions of 1,25 dihydroxyvitamin D3; EGF/EGFR signaling pathway; Resistin as a regulator of inflammation; Vitamin D in inflammatory diseases; Signal transduction through IL1R; Regulatory circuits of the STAT3 signaling pathway; Leukocyte-intrinsic Hippo pathway functions; Translation inhibitors in chronically activated PDGFRA cells; Gastrin signaling pathway; Hepatitis B infection; Netrin-UNC5B signaling pathway; FGFR3 signaling in chondrocyte proliferation and terminal differentiation; Osteoblast differentiation and related diseases; Insulin signaling; Host-pathogen interaction of human coronaviruses - apoptosis; Host-pathogen interaction of human coronaviruses - MAPK signaling; Host-pathogen interaction of human coronaviruses - interferon induction; Neuroinflammation; Pleural mesothelioma; Th17 cell differentiation pathway; GDNF signaling; Hippocampal synaptogenesis and neurogenesis; Comprehensive IL-17A signaling; IL-26 signaling pathways; A network map of Macrophage-stimulating protein (MSP) signaling; Interferon type I signaling pathways; T-cell receptor signaling pathway; Estrogen signaling pathway; Serotonin HTR1 group and FOS pathway; Monoamine transport; Toll-like receptor signaling pathway"	"89"	"0"	"15.9"	"12.9"	"28.8"	"8.3"	"6.5"	"6.2"	"31.9"	"0.0"	"3.4"	"7.3"	"2.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04080"	"Cystatin-B OS=Homo sapiens OX=9606 GN=CSTB PE=1 SV=2"	"9"	"1"	"1"	"1"	"98"	"11.1"	"7.56"	""	"2.29"	""	"1"	"other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00031"	"1476"	"ENSG00000160213"	"CSTB"	"hsa:1476; P04080"	"Neutrophil degranulation"	""	"1"	"0"	"70.2"	"61.0"	"187.2"	"71.5"	"96.2"	"69.9"	"224.8"	"61.1"	"78.8"	"110.3"	"106.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UPT5"	"Exocyst complex component 7 OS=Homo sapiens OX=9606 GN=EXOC7 PE=1 SV=3"	"2"	"1"	"2"	"1"	"735"	"83.3"	"6.79"	"321.35"	"2.29"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf03081"	"23265"	"ENSG00000182473"	"EXOC7"	"B5MC69; B8XXP2; hsa:23265; Q8ND93; Q8WV91; Q96FF0; Q9H8C3; Q9H9X3; Q9HA32; Q9UPT5"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"Angiopoietin-like protein 8 regulatory pathway; Ciliary landscape"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96ME1"	"F-box/LRR-repeat protein 18 OS=Homo sapiens OX=9606 GN=FBXL18 PE=1 SV=2"	"1"	"1"	"1"	"1"	"805"	"88.3"	"8.32"	""	"2.29"	""	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96D71"	"RalBP1-associated Eps domain-containing protein 1 OS=Homo sapiens OX=9606 GN=REPS1 PE=1 SV=3"	"1"	"1"	"2"	"1"	"796"	"86.6"	"5.69"	"238.51"	"2.29"	"1"	"1"	"transport"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf12763"	"85021"	"ENSG00000135597"	"REPS1"	"B7ZBZ8; B7ZBZ9; B7ZC00; hsa:85021; J3KP76; Q5JWJ5; Q5JWJ6; Q5JWJ7; Q8NDR7; Q8WU62; Q96D71; Q9BXY9"	"Cargo recognition for clathrin-mediated endocytosis"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75915"	"PRA1 family protein 3 OS=Homo sapiens OX=9606 GN=ARL6IP5 PE=1 SV=1"	"4"	"1"	"2"	"1"	"188"	"21.6"	"9.77"	"251.31"	"2.28"	"1"	"1"	"other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi"	""	"Pf03208"	"10550"	"ENSG00000144746"	"ARL6IP5"	"B2R6V5; hsa:10550; O75915; Q53ES3; Q5KU08"	"Glutamate Neurotransmitter Release Cycle"	""	"1"	"0"	"73.1"	"67.1"	"299.2"	"78.8"	"75.9"	"47.8"	"319.2"	"38.5"	"56.1"	"43.8"	"54.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H5N1"	"Rab GTPase-binding effector protein 2 OS=Homo sapiens OX=9606 GN=RABEP2 PE=1 SV=2"	"3"	"2"	"3"	"1"	"569"	"63.5"	"4.78"	"556.09"	"2.28"	"2"	"1"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity"	"Pf03528, Pf09311"	"79874"	"ENSG00000177548"	"RABEP2"	"hsa:79874; Q9H5N1"	""	"Ciliary landscape; 16p11.2 distal deletion syndrome"	"2"	"0"	"17.6"	"17.6"	"54.7"	"16.0"	"18.6"	"7.7"	"67.4"	"8.1"	"10.9"	"13.4"	"6.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86UD5"	"Sodium/hydrogen exchanger 9B2 OS=Homo sapiens OX=9606 GN=SLC9B2 PE=1 SV=2"	"1"	"1"	"2"	"1"	"537"	"57.5"	"6.71"	"253.57"	"2.28"	"1"	"1"	"transport;other biological processes"	"plasma membrane;other membranes;cytoskeleton;mitochondrion;ER/Golgi;other cytoplasmic organelle"	"transporter activity;other molecular function"	"Pf00999"	"133308"	"ENSG00000164038"	"SLC9B2"	"B5ME52; hsa:133308; Q6ZMD8; Q86UD5; Q96D95"	"Stimuli-sensing channels"	""	"1"	"0"	"165.8"	"140.8"	"516.6"	"138.9"	"105.4"	"90.1"	"389.3"	"31.6"	"75.7"	"114.2"	"188.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UJ83"	"2-hydroxyacyl-CoA lyase 1 OS=Homo sapiens OX=9606 GN=HACL1 PE=1 SV=2"	"3"	"1"	"2"	"1"	"578"	"63.7"	"7.36"	"281.01"	"2.28"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00205, Pf02775, Pf02776"	"26061"	"ENSG00000131373"	"HACL1"	"B4DWI1; B4DXI5; E9PEN4; hsa:26061; Q9BV42; Q9P0A2; Q9UJ83"	"Peroxisomal protein import; Alpha-oxidation of phytanate"	""	"2"	"0"	"8.8"	"9.8"	"47.0"	"12.5"	"11.9"	"9.4"	"39.6"	"4.2"	"12.1"	"11.4"	"13.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51798"	"H(+)/Cl(-) exchange transporter 7 OS=Homo sapiens OX=9606 GN=CLCN7 PE=1 SV=2"	"1"	"1"	"1"	"1"	"805"	"88.6"	"8.43"	""	"2.28"	""	"1"	"transport;other biological processes"	"other membranes;other cell component"	"transporter activity;other molecular function"	"Pf00571, Pf00654"	"1186"	"ENSG00000103249"	"CLCN7"	"A6NEJ7; A8K5T9; A8K7X1; B3KPN3; E9PDB9; hsa:1186; P51798; Q9NYX5"	"Stimuli-sensing channels"	"Autosomal recessive osteopetrosis pathways"	"2"	"0"	"91.0"	"134.2"	"456.3"	"117.2"	"104.8"	"99.2"	"374.7"	"48.2"	"80.6"	"63.4"	"67.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NPQ8"	"Synembryn-A OS=Homo sapiens OX=9606 GN=RIC8A PE=1 SV=3"	"3"	"2"	"4"	"1"	"531"	"59.7"	"5.33"	"834.63"	"2.28"	"2"	"1"	"cell adhesion;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"enzyme regulator activity;other molecular function"	"Pf10165"	"60626"	"ENSG00000177963"	"RIC8A"	"hsa:60626; Q0P508; Q2T9J1; Q7Z352; Q96EZ1; Q96SZ2; Q9H064; Q9H5H3; Q9H9E7; Q9NPQ8"	""	""	"0"	"0"	"6.3"	"10.1"	"108.9"	"7.5"	"0.6"	"5.1"	"82.6"	"2.1"	"0.0"	"0.0"	"0.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86W92"	"Liprin-beta-1 OS=Homo sapiens OX=9606 GN=PPFIBP1 PE=1 SV=2"	"1"	"1"	"1"	"1"	"1011"	"114.0"	"5.55"	""	"2.28"	""	"1"	"cell adhesion;cell organization and biogenesis"	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf00536, Pf07647"	"8496"	"ENSG00000110841"	"PPFIBP1"	"hsa:8496; O75336; Q86W92; Q86X70; Q9NY03; Q9ULJ0"	"Signaling by ALK fusions and activated point mutants; Receptor-type tyrosine-protein phosphatases"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9NR56"	"Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"388"	"41.8"	"8.90"	"250.68"	"2.28"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00642, Pf14608"	"4154"	"ENSG00000152601"	"MBNL1"	"E9PBW7; hsa:4154; O43311; O43797; Q86UV8; Q86UV9; Q96P92; Q96RE3; Q9NR56"	""	"Adipogenesis"	"1"	"0"	"58.0"	"71.5"	"234.0"	"70.1"	"73.7"	"55.2"	"290.9"	"60.2"	"131.6"	"150.9"	"197.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11233"	"Ras-related protein Ral-A OS=Homo sapiens OX=9606 GN=RALA PE=1 SV=1"	"3"	"1"	"2"	"1"	"206"	"23.6"	"7.11"	"245.77"	"2.27"	"1"	"1"	"cell cycle OR cell proliferation;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;mitochondrion;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00071"	"5898"	"ENSG00000006451"	"RALA"	"A4D1W3; hsa:5898; P11233"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Translocation of SLC2A4 (GLUT4) to the plasma membrane; p38MAPK events"	"RalA downstream regulated genes; Chromosomal and microsatellite instability in colorectal cancer ; Ras signaling; Pancreatic adenocarcinoma pathway; EGF/EGFR signaling pathway"	"8"	"0"	"66.0"	"85.5"	"250.0"	"65.9"	"56.4"	"49.1"	"292.1"	"43.9"	"57.1"	"62.9"	"46.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z4Q2"	"HEAT repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=HEATR3 PE=1 SV=2"	"3"	"2"	"3"	"2"	"680"	"74.5"	"5.11"	"666.76"	"2.27"	"2"	"1"	"transport;other biological processes"	""	"other molecular function"	"Pf13513"	"55027"	"ENSG00000155393"	"HEATR3"	"A8K1N4; hsa:55027; Q7Z4Q2; Q8N525; Q8WV56; Q96CC9; Q9NWN7"	""	""	"0"	"0"	"9.1"	"8.8"	"54.0"	"10.6"	"4.4"	"5.2"	"51.7"	"2.3"	"0.0"	"3.7"	"4.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NV96"	"Cell cycle control protein 50A OS=Homo sapiens OX=9606 GN=TMEM30A PE=1 SV=1"	"2"	"1"	"2"	"1"	"361"	"40.7"	"8.59"	"232.10"	"2.27"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf03381"	"55754"	"ENSG00000112697"	"TMEM30A"	"A8K9V8; E1P539; hsa:55754; Q658Z3; Q96H09; Q9NSL9; Q9NV96"	"Neutrophil degranulation"	""	"1"	"0"	"14.7"	"12.5"	"83.2"	"17.0"	"14.0"	"11.1"	"86.0"	"3.7"	"3.4"	"8.9"	"5.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96FC9"	"ATP-dependent DNA helicase DDX11 OS=Homo sapiens OX=9606 GN=DDX11 PE=1 SV=1"	"1"	"1"	"1"	"1"	"970"	"108.2"	"7.31"	""	"2.27"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06733, Pf13307"	"1663"	"ENSG00000013573"	"DDX11"	"hsa:1663; Q13333; Q86VQ4; Q86W62; Q92498; Q92770; Q92998; Q92999; Q96FC9"	"XBP1(S) activates chaperone genes"	""	"1"	"0"	"34.5"	"35.6"	"97.2"	"34.3"	"36.7"	"32.5"	"88.0"	"10.9"	"16.3"	"19.7"	"10.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5Q9"	"General transcription factor 3C polypeptide 3 OS=Homo sapiens OX=9606 GN=GTF3C3 PE=1 SV=1"	"1"	"1"	"2"	"1"	"886"	"101.2"	"5.07"	"424.34"	"2.27"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13181"	"9330"	"ENSG00000119041"	"GTF3C3"	"hsa:9330; Q4ZG48; Q86XJ8; Q8WX84; Q96B44; Q9H5I8; Q9NT97; Q9Y5Q9"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter"	""	"3"	"0"	"23.4"	"20.3"	"66.1"	"23.3"	"19.1"	"13.2"	"83.8"	"10.1"	"14.6"	"10.9"	"10.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NZN3"	"EH domain-containing protein 3 OS=Homo sapiens OX=9606 GN=EHD3 PE=1 SV=2"	"4"	"2"	"3"	"1"	"535"	"60.8"	"6.57"	"627.34"	"2.27"	"2"	"1"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00350, Pf12763, Pf16880, Pf18150"	"30845"	"ENSG00000013016"	"EHD3"	"B4DFR5; D6W574; hsa:30845; Q8N514; Q9NZB3; Q9NZN3"	"Factors involved in megakaryocyte development and platelet production"	"Ciliary landscape"	"2"	"0"	"11.3"	"12.1"	"91.7"	"15.0"	"6.1"	"2.9"	"161.9"	"4.9"	"6.5"	"6.8"	"10.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13769"	"THO complex subunit 5 homolog OS=Homo sapiens OX=9606 GN=THOC5 PE=1 SV=2"	"2"	"1"	"1"	"1"	"683"	"78.5"	"6.87"	""	"2.26"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf09766"	"8563"	"ENSG00000100296"	"THOC5"	"hsa:8563; O60839; Q13769; Q9UPZ5"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Signaling by CSF1 (M-CSF) in myeloid cells"	""	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94915"	"Protein furry homolog-like OS=Homo sapiens OX=9606 GN=FRYL PE=1 SV=2"	"0"	"1"	"1"	"1"	"3013"	"339.4"	"5.58"	""	"2.26"	""	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"other cell component"	""	"Pf14222, Pf14225, Pf14228, Pf19421"	"285527"	"ENSG00000075539"	"FRYL"	"hsa:285527; O94915; O95640; Q8WTZ5; Q9NT40"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q02224"	"Centromere-associated protein E OS=Homo sapiens OX=9606 GN=CENPE PE=1 SV=2"	"1"	"2"	"2"	"1"	"2701"	"316.2"	"5.64"	"242.63"	"2.26"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225"	"1062"	"ENSG00000138778"	"CENPE"	"A6NKY9; A8K2U7; hsa:1062; Q02224; Q4LE75"	"Separation of Sister Chromatids; RHO GTPases Activate Formins; MHC class II antigen presentation; COPI-dependent Golgi-to-ER retrograde traffic; Resolution of Sister Chromatid Cohesion; EML4 and NUDC in mitotic spindle formation; Kinesins; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"Regulation of sister chromatid separation at the metaphase-anaphase transition"	"10"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9GZM8"	"Nuclear distribution protein nudE-like 1 OS=Homo sapiens OX=9606 GN=NDEL1 PE=1 SV=1"	"4"	"1"	"2"	"1"	"345"	"38.4"	"5.24"	"333.05"	"2.26"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf04880"	"81565"	"ENSG00000166579"	"NDEL1"	"B3KP93; D3DTS0; hsa:81565; J3QT32; Q86T80; Q8TAR7; Q9GZM8; Q9UH50"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"Neurogenesis regulation in the olfactory epithelium"	"7"	"0"	"14.3"	"15.1"	"58.5"	"14.6"	"13.6"	"11.6"	"53.1"	"3.9"	"13.5"	"8.5"	"9.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H425"	"Uncharacterized protein C1orf198 OS=Homo sapiens OX=9606 GN=C1orf198 PE=1 SV=1"	"4"	"1"	"2"	"1"	"327"	"36.3"	"5.72"	"376.19"	"2.26"	"1"	"1"	""	"cytosol"	""	"Pf15797"	"84886"	"ENSG00000119280"	"C1orf198"	"A8K8R8; B3KTW1; G5EA08; hsa:84886; Q9H425"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WWV3"	"Reticulon-4-interacting protein 1, mitochondrial OS=Homo sapiens OX=9606 GN=RTN4IP1 PE=1 SV=2"	"3"	"1"	"2"	"1"	"396"	"43.6"	"9.11"	"375.97"	"2.26"	"1"	"1"	"developmental processes;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf08240, Pf13602"	"84816"	"ENSG00000130347"	"RTN4IP1"	"hsa:84816; Q8N9B3; Q8WWV3; Q8WZ66; Q9BRA4"	""	""	"0"	"0"	"6.3"	"7.1"	"35.4"	"5.9"	"4.2"	"4.7"	"47.2"	"3.3"	"3.7"	"6.8"	"2.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95229"	"ZW10 interactor OS=Homo sapiens OX=9606 GN=ZWINT PE=1 SV=2"	"5"	"1"	"2"	"1"	"277"	"31.3"	"5.15"	"231.76"	"2.26"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf15556"	"11130"	"ENSG00000122952"	"ZWINT"	"A6NNV6; hsa:11130; O95229; Q0D2I3; Q9BWD0"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	""	"6"	"0"	"36.0"	"34.4"	"119.2"	"33.4"	"43.0"	"31.4"	"133.7"	"27.1"	"70.5"	"59.5"	"70.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q2TAY7"	"WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"513"	"57.5"	"7.18"	"240.98"	"2.25"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf00400, Pf17814"	"55234"	"ENSG00000122692"	"SMU1"	"B4E3L0; hsa:55234; Q2TAY7; Q9BU59; Q9HA96; Q9NVD1"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q86Y56"	"Dynein assembly factor 5, axonemal OS=Homo sapiens OX=9606 GN=DNAAF5 PE=1 SV=4"	"1"	"1"	"2"	"1"	"855"	"93.5"	"6.42"	"305.85"	"2.25"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"other cell component"	"other molecular function"	""	"54919"	"ENSG00000164818"	"DNAAF5"	"hsa:54919; Q69YL1; Q86Y56; Q96FI9; Q9NX75"	""	"Ciliopathies"	"1"	"0"	"9.3"	"6.4"	"42.0"	"6.1"	"8.0"	"1.7"	"34.8"	"3.6"	"3.4"	"7.7"	"5.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15388"	"Mitochondrial import receptor subunit TOM20 homolog OS=Homo sapiens OX=9606 GN=TOMM20 PE=1 SV=1"	"5"	"1"	"2"	"1"	"145"	"16.3"	"8.60"	"284.15"	"2.25"	"1"	"1"	"cell organization and biogenesis;transport"	"other membranes;cytoskeleton;mitochondrion;other cell component"	"transporter activity;other molecular function"	"Pf02064"	"9804"	"ENSG00000173726"	"TOMM20"	"A8K195; hsa:9804; Q15388; Q498B3; Q6IBT4"	"Ub-specific processing proteases; Mitochondrial protein import; PINK1-PRKN Mediated Mitophagy"	""	"3"	"0"	"42.4"	"40.4"	"185.8"	"42.9"	"43.3"	"29.9"	"114.3"	"13.0"	"21.5"	"15.3"	"22.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86SQ9"	"Dehydrodolichyl diphosphate synthase complex subunit DHDDS OS=Homo sapiens OX=9606 GN=DHDDS PE=1 SV=3"	"3"	"1"	"2"	"1"	"333"	"38.6"	"8.28"	"279.73"	"2.25"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf01255"	"79947"	"ENSG00000117682"	"DHDDS"	"B7Z4B9; B7ZB20; D3DPK7; D3DPK8; D3DPK9; E9KL43; hsa:79947; Q5T0A4; Q86SQ9; Q8NE90; Q9BTG5; Q9BTK3; Q9H905"	"Synthesis of Dolichyl-phosphate; Defective DHDDS causes RP59"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q969Z0"	"FAST kinase domain-containing protein 4 OS=Homo sapiens OX=9606 GN=TBRG4 PE=1 SV=1"	"1"	"1"	"2"	"1"	"631"	"70.7"	"7.42"	"313.62"	"2.25"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"mitochondrion;other cell component"	""	"Pf06743, Pf08368, Pf08373"	"9238"	"ENSG00000136270"	"TBRG4"	"A4D2L2; A4D2L3; D3DVL5; D3DVL6; hsa:9238; O14710; Q53GI8; Q8NDM4; Q969Z0; Q9BUC6; Q9Y2F6"	""	""	"0"	"0"	"92.5"	"105.1"	"349.8"	"108.1"	"80.7"	"73.5"	"328.2"	"40.5"	"53.6"	"58.9"	"56.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H871"	"E3 ubiquitin-protein transferase RMND5A OS=Homo sapiens OX=9606 GN=RMND5A PE=1 SV=1"	"3"	"1"	"1"	"1"	"391"	"44.0"	"6.06"	""	"2.24"	""	"1"	"protein metabolism;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf10607, Pf13445"	"64795"	"ENSG00000153561"	"RMND5A"	"D6W5M6; hsa:64795; Q6NTF0; Q9H6W5; Q9H871; Q9H9H2"	""	"Ciliary landscape"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"O14531"	"Dihydropyrimidinase-related protein 4 OS=Homo sapiens OX=9606 GN=DPYSL4 PE=1 SV=2"	"2"	"1"	"1"	"1"	"572"	"61.8"	"7.09"	""	"2.24"	""	"1"	"developmental processes"	"cytosol"	"cytoskeletal activity;other molecular function"	"Pf01979"	"10570"	"ENSG00000151640"	"DPYSL4"	"B2RMQ1; D3DRG5; hsa:10570; O00240; O14531; Q5T0Q7"	"CRMPs in Sema3A signaling"	""	"1"	"0"	"4.3"	"7.5"	"37.2"	"9.0"	"9.4"	"3.1"	"38.2"	"5.9"	"9.8"	"0.0"	"5.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14735"	"CDP-diacylglycerol--inositol 3-phosphatidyltransferase OS=Homo sapiens OX=9606 GN=CDIPT PE=1 SV=1"	"6"	"1"	"2"	"1"	"213"	"23.5"	"8.03"	"242.28"	"2.24"	"1"	"1"	"other metabolic processes"	"plasma membrane;other membranes;ER/Golgi"	"other molecular function"	"Pf01066"	"10423"	"ENSG00000103502"	"CDIPT"	"B4DUV0; H3BTV1; hsa:10423; O14735; Q6FGU1; Q6ZN70"	"Synthesis of PI"	"Glycerolipids and glycerophospholipids; 16p11.2 proximal deletion syndrome"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q15027"	"Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ACAP1 PE=1 SV=1"	"2"	"1"	"1"	"1"	"740"	"81.5"	"7.66"	""	"2.24"	""	"1"	"transport"	"other membranes;other cytoplasmic organelle"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf01412, Pf16746"	"9744"	"ENSG00000072818; ENSG00000288169"	"ACAP1"	"hsa:9744; Q15027; Q53XN9"	""	"Nucleotide-binding oligomerization domain (NOD) pathway"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q4LE39"	"AT-rich interactive domain-containing protein 4B OS=Homo sapiens OX=9606 GN=ARID4B PE=1 SV=2"	"1"	"1"	"2"	"1"	"1312"	"147.7"	"5.12"	"231.65"	"2.24"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;mitochondrion;nucleus"	"nucleic acid binding activity"	"Pf01388, Pf08169, Pf11717"	"51742"	"ENSG00000054267"	"ARID4B"	"A1L465; hsa:51742; Q3MHV4; Q4LE39; Q5HY99; Q5T2C2; Q5T2C3; Q5T2C4; Q5T2C5; Q5T2C6; Q6P600; Q86UX1; Q86WR4; Q9H915; Q9NYU3; Q9NZB6; Q9NZG4; Q9P2W4; Q9UF62; Q9Y6E1"	"Potential therapeutics for SARS; HDACs deacetylate histones; NoRC negatively regulates rRNA expression"	"Pathways affected in adenoid cystic carcinoma"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q13015"	"Protein AF1q OS=Homo sapiens OX=9606 GN=MLLT11 PE=1 SV=1"	"13"	"1"	"1"	"1"	"90"	"10.1"	"4.54"	""	"2.24"	""	"1"	"signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus"	""	"Pf15017"	"10962"	"ENSG00000213190"	"MLLT11"	"hsa:10962; Q13015"	""	""	"0"	"0"	"64.8"	"88.2"	"192.4"	"61.6"	"66.3"	"55.9"	"223.4"	"60.3"	"77.6"	"75.9"	"112.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96I59"	"Probable asparagine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=NARS2 PE=1 SV=3"	"3"	"1"	"2"	"1"	"477"	"54.1"	"7.24"	"232.97"	"2.24"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00152, Pf01336"	"79731"	"ENSG00000137513"	"NARS2"	"G3V178; hsa:79731; Q96I59"	"Mitochondrial tRNA aminoacylation"	"Ectoderm differentiation"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P48723"	"Heat shock 70 kDa protein 13 OS=Homo sapiens OX=9606 GN=HSPA13 PE=1 SV=1"	"2"	"1"	"1"	"1"	"471"	"51.9"	"5.76"	""	"2.24"	""	"1"	"other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00012"	"6782"	"ENSG00000155304"	"HSPA13"	"B2R616; hsa:6782; P48723; Q8NE40"	"Regulation of HSF1-mediated heat shock response"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q86WR7"	"Proline and serine-rich protein 2 OS=Homo sapiens OX=9606 GN=PROSER2 PE=1 SV=2"	"3"	"1"	"2"	"1"	"435"	"45.8"	"7.20"	"292.03"	"2.23"	"1"	"1"	""	""	""	"Pf15385"	"254427"	"ENSG00000148426"	"PROSER2"	"D3DRR8; hsa:254427; Q5W0J9; Q5W0K0; Q5W0K1; Q5W0K2; Q6PJC8; Q86WR7; Q8N317"	""	""	"0"	"0"	"3.5"	"10.4"	"18.9"	"6.5"	"9.9"	"4.8"	"29.2"	"5.5"	"9.6"	"5.9"	"7.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5THK1"	"Protein PRR14L OS=Homo sapiens OX=9606 GN=PRR14L PE=1 SV=1"	"1"	"1"	"1"	"1"	"2151"	"237.2"	"6.33"	""	"2.23"	""	"1"	""	""	""	"Pf15386"	"253143"	"ENSG00000183530"	"PRR14L"	"hsa:253143; Q5THK1; Q5THK4; Q6ZNN1; Q6ZWH0; Q8IW74; Q9H5T4"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q16881"	"Thioredoxin reductase 1, cytoplasmic OS=Homo sapiens OX=9606 GN=TXNRD1 PE=1 SV=3"	"2"	"1"	"2"	"1"	"649"	"70.9"	"7.39"	"284.67"	"2.23"	"1"	"1"	"cell cycle OR cell proliferation;developmental processes;signal transduction;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00462, Pf02852, Pf07992"	"7296"	"ENSG00000198431"	"TXNRD1"	"B7Z1F4; B7Z3Y8; B7Z904; E9PMY9; F5H780; hsa:7296; Q16881; Q6FI31; Q6VB40; Q6VB41; Q6VB42; Q6VBP2; Q6VBP3; Q6VBP4; Q6VBP5; Q6VBP9; Q6VBQ0; Q6YNQ1; Q76P53; Q7LA96; Q8WVC8; Q99475; Q9UES8; Q9UH79"	"Interconversion of nucleotide di- and triphosphates; TP53 Regulates Metabolic Genes; PPARA activates gene expression; Detoxification of Reactive Oxygen Species; NFE2L2 regulating anti-oxidant/detoxification enzymes; Metabolism of ingested H2SeO4 and H2SeO3 into H2Se; Uptake and function of diphtheria toxin; Metabolism of ingested MeSeO2H into MeSeH"	"Selenium micronutrient network; Selenium micronutrient network ; Selenium micronutrient network; Nuclear receptors meta-pathway; NRF2 pathway; Oxidative stress response; Ferroptosis"	"15"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q8NAN2"	"Mitoguardin 1 OS=Homo sapiens OX=9606 GN=MIGA1 PE=1 SV=1"	"3"	"1"	"1"	"1"	"632"	"71.0"	"5.63"	""	"2.23"	""	"1"	"cell organization and biogenesis"	"plasma membrane;other membranes;mitochondrion"	"other molecular function"	"Pf10265"	"374986"	"ENSG00000180488"	"MIGA1"	"hsa:374986; Q6MZG0; Q8NAN2"	"Synthesis of PA"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y6B6"	"GTP-binding protein SAR1b OS=Homo sapiens OX=9606 GN=SAR1B PE=1 SV=1"	"7"	"2"	"3"	"1"	"198"	"22.4"	"6.11"	"500.58"	"2.23"	"2"	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;ER/Golgi"	"other molecular function"	"Pf00025"	"51128"	"ENSG00000152700"	"SAR1B"	"D3DQA4; hsa:51128; Q567T4; Q9Y6B6"	"SARS-CoV-2 activates/modulates innate and adaptive immune responses; MHC class II antigen presentation; COPII-mediated vesicle transport; Cargo concentration in the ER; Regulation of cholesterol biosynthesis by SREBP (SREBF); Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Chylomicron assembly"	"Sterol regulatory element-binding proteins (SREBP) signaling; Cholesterol metabolism; Enterocyte cholesterol metabolism"	"10"	"0"	"49.4"	"69.8"	"181.3"	"61.6"	"79.5"	"75.4"	"245.9"	"64.3"	"95.8"	"57.2"	"48.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86W56"	"Poly(ADP-ribose) glycohydrolase OS=Homo sapiens OX=9606 GN=PARG PE=1 SV=1"	"2"	"1"	"1"	"1"	"976"	"111.0"	"6.43"	""	"2.23"	""	"1"	"DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf05028"	"670; 8505"	"ENSG00000227345"	"PARG"	"A5YBK3; B2RC24; B4DIU5; B4DYR4; hsa:8505; I6RUV3; Q6E4P6; Q6E4P7; Q7Z742; Q86W56; Q9Y4W7"	"POLB-Dependent Long Patch Base Excision Repair"	"10q11.21q11.23 copy number variation syndrome"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86T03"	"Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase OS=Homo sapiens OX=9606 GN=PIP4P1 PE=1 SV=1"	"4"	"1"	"2"	"1"	"277"	"29.5"	"8.91"	"260.02"	"2.23"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;nucleus;other cytoplasmic organelle"	"other molecular function"	"Pf09788"	"90809"	"ENSG00000165782"	"PIP4P1"	"B2RA35; hsa:90809; Q86T03; Q86U09; Q8WUC0; Q9BU67; Q9NSU8"	"PI5P Regulates TP53 Acetylation; Synthesis of PIPs in the nucleus"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75554"	"WW domain-binding protein 4 OS=Homo sapiens OX=9606 GN=WBP4 PE=1 SV=1"	"3"	"1"	"2"	"1"	"376"	"42.5"	"5.57"	"323.81"	"2.23"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00397, Pf06220"	"11193"	"ENSG00000120688"	"WBP4"	"B7Z4M2; hsa:11193; O75554; Q32P29"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q92797"	"Symplekin OS=Homo sapiens OX=9606 GN=SYMPK PE=1 SV=2"	"1"	"1"	"2"	"1"	"1274"	"141.1"	"6.13"	"280.42"	"2.22"	"1"	"1"	"cell adhesion;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	""	"Pf11935, Pf12295"	"8189"	"ENSG00000125755"	"SYMPK"	"hsa:8189; O00521; O00689; O00733; Q59GT5; Q8N2U5; Q92797"	"Transport of Mature mRNA Derived from an Intronless Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	""	"5"	"0"	"20.0"	"13.1"	"58.2"	"15.6"	"14.7"	"8.1"	"68.7"	"12.2"	"20.1"	"20.1"	"16.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q1ED39"	"Lysine-rich nucleolar protein 1 OS=Homo sapiens OX=9606 GN=KNOP1 PE=1 SV=1"	"2"	"1"	"1"	"1"	"458"	"51.6"	"9.86"	""	"2.22"	""	"1"	""	"nucleus"	""	"Pf15477"	"400506"	"ENSG00000103550"	"KNOP1"	"hsa:400506; O43328; Q1ED39; Q5FWF3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4J8"	"Dystrobrevin alpha OS=Homo sapiens OX=9606 GN=DTNA PE=1 SV=2"	"1"	"1"	"1"	"1"	"743"	"83.8"	"6.89"	""	"2.22"	""	"1"	"cell-cell signaling;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00569, Pf09068, Pf09069"	"1837"	"ENSG00000134769"	"DTNA"	"A8K541; A8MSZ0; A8MUY4; B4DGS6; B4DIR0; B4DIU8; hsa:1837; M0QYX6; M0R397; O15332; O15333; O75697; Q13197; Q13198; Q13199; Q13498; Q13499; Q13500; Q59GK7; Q9BS59; Q9Y4J8"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q8IWA4"	"Mitofusin-1 OS=Homo sapiens OX=9606 GN=MFN1 PE=1 SV=3"	"1"	"1"	"1"	"1"	"741"	"84.1"	"6.33"	""	"2.22"	""	"1"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf00350, Pf04799"	"55669"	"ENSG00000171109"	"MFN1"	"A0A0C4DFN1; B2RAR1; D3DNR6; hsa:55669; O15323; O60639; Q8IWA4; Q9BZB5; Q9NWQ2"	"Factors involved in megakaryocyte development and platelet production; PINK1-PRKN Mediated Mitophagy; RHOT2 GTPase cycle"	""	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q92738"	"USP6 N-terminal-like protein OS=Homo sapiens OX=9606 GN=USP6NL PE=1 SV=3"	"2"	"1"	"2"	"1"	"828"	"94.0"	"9.07"	"319.76"	"2.22"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00566"	"9712"	"ENSG00000148429"	"USP6NL"	"A8KA79; hsa:9712; Q15400; Q5VV10; Q7L0K9; Q92738"	"Retrograde transport at the Trans-Golgi-Network"	"EGF/EGFR signaling pathway"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16537"	"Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform OS=Homo sapiens OX=9606 GN=PPP2R5E PE=1 SV=1"	"3"	"1"	"2"	"1"	"467"	"54.7"	"6.95"	"299.99"	"2.22"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction"	"cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf01603"	"5529"	"ENSG00000154001"	"PPP2R5E"	"A4FU37; B7ZAW5; B7ZKK8; B7ZKK9; hsa:5529; J3KQN6; Q16537; Q52LW4"	"Separation of Sister Chromatids; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Negative regulation of MAPK pathway; Disassembly of the destruction complex and recruitment of AXIN to the membrane; RAF activation; Beta-catenin phosphorylation cascade; Signaling by GSK3beta mutants; CTNNB1 S33 mutants aren't phosphorylated; CTNNB1 S37 mutants aren't phosphorylated; CTNNB1 S45 mutants aren't phosphorylated; CTNNB1 T41 mutants aren't phosphorylated; APC truncation mutants have impaired AXIN binding; AXIN missense mutants destabilize the destruction complex; Truncations of AMER1 destabilize the destruction complex; Platelet sensitization by LDL; CTLA4 inhibitory signaling"	"Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Wnt signaling pathway and pluripotency; PI3K-Akt signaling pathway; Glycogen synthesis and degradation; Cohesin complex - Cornelia de Lange syndrome; DNA damage response (only ATM dependent)"	"28"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q8IZL8"	"Proline-, glutamic acid- and leucine-rich protein 1 OS=Homo sapiens OX=9606 GN=PELP1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1130"	"119.6"	"4.34"	"257.00"	"2.21"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf08166, Pf08167"	"27043"	"ENSG00000141456"	"PELP1"	"hsa:27043; O15450; Q5EGN3; Q6NTE6; Q8IZL8; Q96FT1; Q9BU60"	"Major pathway of rRNA processing in the nucleolus and cytosol; PTK6 Expression"	""	"2"	"0"	"8.9"	"7.7"	"38.6"	"13.6"	"14.4"	"4.7"	"27.8"	"5.9"	"8.9"	"5.6"	"5.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75223"	"Gamma-glutamylcyclotransferase OS=Homo sapiens OX=9606 GN=GGCT PE=1 SV=1"	"11"	"2"	"3"	"2"	"188"	"21.0"	"5.14"	"529.49"	"2.21"	"2"	"1"	"cell organization and biogenesis;signal transduction"	"cytosol"	"other molecular function"	"Pf13772"	"79017"	"ENSG00000006625"	"GGCT"	"B2RDN0; B8ZZN4; B8ZZR8; hsa:79017; O75223; Q9BS37"	"Glutathione synthesis and recycling"	""	"1"	"0"	"86.9"	"57.8"	"198.1"	"52.5"	"52.0"	"32.3"	"244.5"	"38.7"	"69.1"	"61.1"	"68.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5VZ89"	"DENN domain-containing protein 4C OS=Homo sapiens OX=9606 GN=DENND4C PE=1 SV=3"	"1"	"1"	"2"	"1"	"1909"	"212.6"	"6.83"	"281.36"	"2.21"	"1"	"1"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity"	"Pf02141, Pf03455, Pf03456"	"55667"	"ENSG00000137145"	"DENND4C"	"A2A3R1; A2A3R2; A2A3R3; A2A3R9; hsa:55667; Q5VZ89; Q6AI48; Q6ZUB3; Q8NCY7; Q9H6N4; Q9NUT1; Q9NWA5; Q9NWT3; R4GN35; R4GNB2"	"RAB GEFs exchange GTP for GDP on RABs"	""	"1"	"0"	"6.9"	"6.1"	"29.6"	"8.1"	"7.3"	"4.9"	"30.0"	"3.6"	"6.2"	"7.6"	"7.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P43304"	"Glycerol-3-phosphate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GPD2 PE=1 SV=3"	"1"	"1"	"2"	"1"	"727"	"80.8"	"7.69"	"233.28"	"2.21"	"1"	"1"	"other metabolic processes"	"other membranes;mitochondrion;other cell component"	"other molecular function"	"Pf01266, Pf16901"	"2820"	"ENSG00000115159"	"GPD2"	"A8K4V0; B3KSA9; hsa:2820; P43304; Q59FR1; Q9HAP9"	"Triglyceride catabolism; Synthesis of PA"	"Fatty acid beta-oxidation"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q4V339"	"COBW domain-containing protein 6 OS=Homo sapiens OX=9606 GN=CBWD6 PE=3 SV=1"	"2"	"1"	"1"	"1"	"395"	"43.9"	"4.87"	""	"2.21"	""	"1"	""	"nucleus;other cell component"	"other molecular function"	"Pf02492, Pf07683"	"644019"	"ENSG00000215126"	"ZNG1F"	"hsa:644019; Q4V339"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61923"	"Coatomer subunit zeta-1 OS=Homo sapiens OX=9606 GN=COPZ1 PE=1 SV=1"	"8"	"1"	"2"	"1"	"177"	"20.2"	"4.81"	"260.93"	"2.21"	"1"	"1"	"transport"	"other membranes;cytosol;ER/Golgi"	""	"Pf01217"	"22818"	"ENSG00000111481"	"COPZ1"	"B4DDX8; B4DHZ0; F8VS17; F8VWL5; hsa:22818; P61923; Q549N6; Q9Y3C3"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NDG6"	"ATP-dependent RNA helicase TDRD9 OS=Homo sapiens OX=9606 GN=TDRD9 PE=2 SV=3"	"1"	"1"	"1"	"1"	"1382"	"155.6"	"7.05"	""	"2.21"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf00567, Pf04408"	"122402"	"ENSG00000156414"	"TDRD9"	"A1A4S7; hsa:122402; Q6ZU54; Q8N7T3; Q8N827; Q8N9V5; Q8NDG6; Q96AS9"	"PIWI-interacting RNA (piRNA) biogenesis"	""	"1"	"0"	"76.3"	"128.6"	"484.9"	"125.7"	"107.4"	"86.5"	"1050.5"	"164.3"	"299.9"	"277.0"	"307.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9ULR3"	"Protein phosphatase 1H OS=Homo sapiens OX=9606 GN=PPM1H PE=1 SV=2"	"2"	"1"	"2"	"1"	"514"	"56.4"	"6.60"	"259.19"	"2.21"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00481"	"57460"	"ENSG00000111110"	"PPM1H"	"B1Q2A9; B2RXG4; hsa:57460; Q6PI86; Q9ULR3"	""	""	"0"	"0"	"5.7"	"6.5"	"37.8"	"12.1"	"7.4"	"7.2"	"46.5"	"11.9"	"11.0"	"9.5"	"8.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NA03"	"Fibrous sheath-interacting protein 1 OS=Homo sapiens OX=9606 GN=FSIP1 PE=2 SV=1"	"1"	"1"	"1"	"1"	"581"	"66.1"	"5.16"	""	"2.21"	""	"1"	""	""	""	"Pf15554"	"161835"	"ENSG00000150667"	"FSIP1"	"hsa:161835; Q6X2C8; Q86Y89; Q8NA03"	""	""	"0"	"0"	"216.3"	"262.0"	"603.5"	"218.2"	"233.8"	"217.8"	"593.0"	"110.5"	"178.2"	"266.2"	"456.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96MU7"	"YTH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=YTHDC1 PE=1 SV=3"	"2"	"1"	"2"	"1"	"727"	"84.6"	"6.23"	"277.74"	"2.21"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;nucleus"	"nucleic acid binding activity"	"Pf04146"	"91746"	"ENSG00000083896; ENSG00000275272"	"YTHDC1"	"hsa:91746; Q4W5Q3; Q7Z622; Q8TF35; Q96MU7"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"P09884"	"DNA polymerase alpha catalytic subunit OS=Homo sapiens OX=9606 GN=POLA1 PE=1 SV=2"	"1"	"2"	"2"	"2"	"1462"	"165.8"	"5.85"	"257.77"	"2.20"	"1"	"1"	"cell cycle OR cell proliferation;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00136, Pf03104, Pf08996, Pf12254"	"5422"	"ENSG00000101868"	"POLA1"	"hsa:5422; P09884; Q86UQ7"	"Activation of the pre-replicative complex; Defective pyroptosis; G1/S-Specific Transcription; Inhibition of replication initiation of damaged DNA by RB1/E2F1; Polymerase switching on the C-strand of the telomere; Telomere C-strand synthesis initiation; DNA replication initiation; Polymerase switching; Removal of the Flap Intermediate"	"Retinoblastoma gene in cancer; Pyrimidine metabolism; DNA replication"	"13"	"0"	"125.1"	"97.4"	"162.7"	"68.8"	"44.2"	"38.6"	"114.0"	"18.3"	"28.9"	"24.4"	"24.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q02153"	"Guanylate cyclase soluble subunit beta-1 OS=Homo sapiens OX=9606 GN=GUCY1B1 PE=1 SV=1"	"2"	"1"	"1"	"1"	"619"	"70.5"	"5.35"	""	"2.20"	""	"1"	"cell-cell signaling;other metabolic processes;signal transduction;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00211, Pf07700, Pf07701"	"2983"	"ENSG00000061918"	"GUCY1B1"	"B7Z426; hsa:2983; Q02153; Q86WY5"	"Smooth Muscle Contraction; Nitric oxide stimulates guanylate cyclase"	"NO/cGMP/PKG mediated neuroprotection; Phosphodiesterases in neuronal function; Antiviral and anti-inflammatory effects of Nrf2 on SARS-CoV-2 pathway; Sildenafil treatment; Cardiomyocyte signaling pathways converging on Titin"	"7"	"0"	"83.8"	"67.9"	"326.5"	"105.4"	"115.7"	"73.4"	"487.6"	"71.9"	"127.0"	"103.6"	"86.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5JTZ9"	"Alanine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=AARS2 PE=1 SV=1"	"1"	"1"	"2"	"1"	"985"	"107.3"	"6.27"	"290.90"	"2.20"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf01411, Pf07973"	"57505"	"ENSG00000124608"	"AARS2"	"A2RRN5; hsa:57505; Q5JTZ9; Q8N198; Q96D02; Q9ULF0"	"Mitochondrial tRNA aminoacylation"	"Primary ovarian insufficiency"	"2"	"0"	"65.8"	"81.5"	"319.5"	"70.9"	"44.5"	"44.5"	"384.1"	"42.3"	"43.1"	"34.0"	"41.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15631"	"Translin OS=Homo sapiens OX=9606 GN=TSN PE=1 SV=1"	"8"	"2"	"2"	"2"	"228"	"26.2"	"6.44"	"512.90"	"2.20"	"1"	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01997"	"7247"	"ENSG00000211460"	"TSN"	"B7Z3X8; hsa:7247; Q15631; Q5U0K7"	"Small interfering RNA (siRNA) biogenesis"	""	"1"	"0"	"119.0"	"146.4"	"568.1"	"147.2"	"132.3"	"100.4"	"686.8"	"92.2"	"118.0"	"86.3"	"63.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14694"	"Ubiquitin carboxyl-terminal hydrolase 10 OS=Homo sapiens OX=9606 GN=USP10 PE=1 SV=2"	"2"	"1"	"2"	"1"	"798"	"87.1"	"5.31"	"232.78"	"2.20"	"1"	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00443, Pf07145"	"9100"	"ENSG00000103194"	"USP10"	"B2RDJ8; B4DS84; hsa:9100; Q14694; Q9BWG7; Q9NSL7"	"Ub-specific processing proteases; Termination of translesion DNA synthesis"	"VEGFA-VEGFR2 signaling"	"3"	"0"	"28.5"	"38.1"	"173.3"	"57.2"	"42.1"	"27.5"	"149.5"	"17.5"	"28.8"	"29.3"	"43.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96DB5"	"Regulator of microtubule dynamics protein 1 OS=Homo sapiens OX=9606 GN=RMDN1 PE=1 SV=1"	"4"	"1"	"2"	"1"	"314"	"35.8"	"8.50"	"256.22"	"2.20"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis"	"cytoskeleton;mitochondrion;other cell component"	"cytoskeletal activity"	""	"51115"	"ENSG00000176623"	"RMDN1"	"A9UMZ8; B4DNF5; B4DZW6; B5MC61; C9JSC6; E7EVI2; hsa:51115; Q96DB5; Q9Y398"	""	""	"0"	"0"	"10.5"	"10.8"	"41.8"	"8.3"	"8.3"	"6.1"	"39.8"	"7.6"	"5.5"	"8.1"	"8.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HBM6"	"Transcription initiation factor TFIID subunit 9B OS=Homo sapiens OX=9606 GN=TAF9B PE=1 SV=1"	"4"	"1"	"1"	"1"	"251"	"27.6"	"9.55"	""	"2.20"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf02291"	"51616"	"ENSG00000187325"	"TAF9B"	"B2RUZ9; hsa:51616; Q9HBM6; Q9Y2S3"	"RNA Polymerase II Pre-transcription Events; Ub-specific processing proteases; Regulation of TP53 Activity through Phosphorylation; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation"	""	"10"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q7Z417"	"Nuclear fragile X mental retardation-interacting protein 2 OS=Homo sapiens OX=9606 GN=NUFIP2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"695"	"76.1"	"8.70"	"332.65"	"2.20"	"1"	"1"	""	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity"	"Pf15293"	"57532"	"ENSG00000108256"	"NUFIP2"	"A1L3A6; A1L3A7; hsa:57532; Q7Z417; Q9P2M5"	""	""	"0"	"0"	"64.8"	"47.9"	"130.4"	"65.2"	"62.6"	"46.6"	"314.2"	"75.0"	"153.8"	"127.6"	"115.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5RKV6"	"Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1"	"3"	"1"	"2"	"1"	"272"	"28.2"	"6.28"	"246.39"	"2.20"	"1"	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	""	"Pf01138"	"118460"	"ENSG00000223496"	"EXOSC6"	"hsa:118460; Q5RKV6"	"Major pathway of rRNA processing in the nucleolus and cytosol; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	""	"6"	"0"	"94.0"	"102.8"	"319.0"	"106.6"	"113.5"	"89.4"	"359.5"	"67.2"	"103.0"	"95.9"	"77.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5T1M5"	"FK506-binding protein 15 OS=Homo sapiens OX=9606 GN=FKBP15 PE=1 SV=2"	"1"	"1"	"1"	"1"	"1219"	"133.5"	"5.20"	""	"2.20"	""	"1"	"transport"	"other membranes;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00254"	"23307"	"ENSG00000119321"	"FKBP15"	"hsa:23307; Q05DK8; Q5T1M2; Q5T1M5; Q6DD85; Q9Y4D0"	""	"TYROBP causal network in microglia"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9BRX5"	"DNA replication complex GINS protein PSF3 OS=Homo sapiens OX=9606 GN=GINS3 PE=1 SV=1"	"4"	"1"	"2"	"1"	"216"	"24.5"	"5.34"	"291.84"	"2.20"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"nucleus"	""	"Pf05916"	"64785"	"ENSG00000181938"	"GINS3"	"B2RDP3; E9PB21; hsa:64785; Q9BRX5; Q9H870"	"Unwinding of DNA"	""	"1"	"0"	"92.9"	"109.1"	"353.1"	"79.0"	"60.1"	"51.2"	"447.5"	"51.0"	"63.6"	"40.1"	"39.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BZI7"	"Regulator of nonsense transcripts 3B OS=Homo sapiens OX=9606 GN=UPF3B PE=1 SV=1"	"1"	"1"	"1"	"1"	"483"	"57.7"	"9.48"	""	"2.20"	""	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity"	"Pf03467"	"65109"	"ENSG00000125351"	"UPF3B"	"D3DWI3; D3DWI4; hsa:65109; Q0VAK8; Q9BZI7; Q9H1J0"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing"	""	"6"	"0"	"177.1"	"164.1"	"610.6"	"175.2"	"187.8"	"134.9"	"572.0"	"89.8"	"144.3"	"132.4"	"117.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13425"	"Beta-2-syntrophin OS=Homo sapiens OX=9606 GN=SNTB2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"540"	"57.9"	"8.82"	"306.23"	"2.20"	"1"	"1"	""	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00595, Pf18012"	"6645"	"ENSG00000168807"	"SNTB2"	"hsa:6645; Q13425; Q9BY09"	""	""	"0"	"0"	"13.1"	"12.7"	"62.9"	"12.9"	"8.7"	"4.7"	"86.8"	"4.2"	"7.8"	"3.0"	"4.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P17707"	"S-adenosylmethionine decarboxylase proenzyme OS=Homo sapiens OX=9606 GN=AMD1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"334"	"38.3"	"6.00"	"233.30"	"2.20"	"1"	"1"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf01536"	"262"	"ENSG00000123505"	"AMD1"	"E1P5F7; hsa:262; P17707; Q5VXN4; Q5VXN6; Q9BWK4"	"Metabolism of polyamines"	"Methionine de novo and salvage pathway"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14789"	"Golgin subfamily B member 1 OS=Homo sapiens OX=9606 GN=GOLGB1 PE=1 SV=2"	"0"	"1"	"1"	"1"	"3259"	"375.8"	"5.00"	""	"2.20"	""	"1"	"cell organization and biogenesis;other biological processes"	"other membranes;cytosol;ER/Golgi"	"nucleic acid binding activity"	""	"2804"	"ENSG00000173230"	"GOLGB1"	"B2ZZ91; D3DN92; E7EP74; F1T0J2; hsa:2804; Q14398; Q14789"	"Golgi Associated Vesicle Biogenesis; COPI-mediated anterograde transport; Signaling by FLT3 fusion proteins"	""	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q7RTN6"	"STE20-related kinase adapter protein alpha OS=Homo sapiens OX=9606 GN=STRADA PE=1 SV=1"	"3"	"1"	"1"	"1"	"431"	"48.3"	"6.48"	""	"2.20"	""	"1"	"cell cycle OR cell proliferation;transport;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00069"	"92335"	"ENSG00000266173"	"STRADA"	"B4DDE3; B4DW17; hsa:92335; J3KTC9; Q5JPI2; Q7RTN6; Q7Z4K9; Q8NC31; Q8NCF1; Q9H272"	"Energy dependent regulation of mTOR by LKB1-AMPK"	"AMP-activated protein kinase signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway"	"3"	"0"	"26.9"	"26.5"	"102.3"	"34.3"	"31.9"	"19.0"	"111.5"	"23.9"	"86.6"	"70.6"	"96.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NBU5"	"ATPase family AAA domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ATAD1 PE=1 SV=1"	"3"	"1"	"2"	"1"	"361"	"40.7"	"6.90"	"276.47"	"2.19"	"1"	"1"	"other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf00004, Pf17862"	"84896"	"ENSG00000138138; ENSG00000283024"	"ATAD1"	"D3DR26; hsa:84896; Q6DKG1; Q6P4B9; Q8N3G1; Q8NBU5; Q8WYR9; Q969Y3"	"Class I peroxisomal membrane protein import"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y6E0"	"Serine/threonine-protein kinase 24 OS=Homo sapiens OX=9606 GN=STK24 PE=1 SV=1"	"4"	"2"	"3"	"2"	"443"	"49.3"	"5.69"	"599.52"	"2.19"	"2"	"1"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"8428"	"ENSG00000102572"	"STK24"	"hsa:8428; O14840; Q5JV92; Q9Y6E0"	"Apoptotic cleavage of cellular proteins"	""	"2"	"0"	"155.9"	"195.8"	"804.1"	"156.7"	"118.0"	"103.7"	"783.5"	"68.3"	"71.2"	"63.3"	"60.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N335"	"Glycerol-3-phosphate dehydrogenase 1-like protein OS=Homo sapiens OX=9606 GN=GPD1L PE=1 SV=1"	"2"	"1"	"2"	"1"	"351"	"38.4"	"7.02"	"315.63"	"2.19"	"1"	"1"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf01210, Pf07479"	"23171"	"ENSG00000152642"	"GPD1L"	"A8K9U3; hsa:23171; Q14702; Q8N335; Q9BRM5"	"Synthesis of PA"	"Sudden infant death syndrome (SIDS) susceptibility pathways"	"2"	"0"	"32.4"	"47.7"	"193.2"	"48.0"	"44.8"	"39.4"	"164.2"	"27.9"	"35.4"	"20.5"	"27.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q969F9"	"Hermansky-Pudlak syndrome 3 protein OS=Homo sapiens OX=9606 GN=HPS3 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1004"	"113.7"	"6.43"	"232.35"	"2.19"	"1"	"1"	"cell organization and biogenesis;transport"	"cytosol;other cytoplasmic organelle;other cell component"	""	"Pf14761, Pf14762, Pf14763"	"84343"	"ENSG00000163755"	"HPS3"	"A8K6G6; hsa:84343; Q8WTV6; Q969F9; Q96AP1; Q96MR3; Q9H608"	""	""	"0"	"0"	"20.3"	"20.8"	"43.1"	"22.8"	"19.4"	"17.9"	"54.3"	"24.4"	"72.9"	"98.1"	"126.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H270"	"Vacuolar protein sorting-associated protein 11 homolog OS=Homo sapiens OX=9606 GN=VPS11 PE=1 SV=1"	"1"	"1"	"1"	"1"	"941"	"107.8"	"7.05"	""	"2.19"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00637, Pf12451, Pf13923"	"55823"	""	"VPS11"	"hsa:55823; Q8WY89; Q96EP8; Q9H270; Q9H6D9; Q9HCS6"	"SARS-CoV-2 modulates autophagy"	"Network map of SARS-CoV-2 signaling pathway"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"P00568"	"Adenylate kinase isoenzyme 1 OS=Homo sapiens OX=9606 GN=AK1 PE=1 SV=3"	"4"	"1"	"2"	"1"	"194"	"21.6"	"8.63"	"262.08"	"2.19"	"1"	"1"	"other metabolic processes"	"cytosol;cytoskeleton;other cell component"	"kinase activity;other molecular function"	"Pf00406"	"203"	"ENSG00000106992"	"AK1"	"hsa:203; P00568; Q9BVK9; Q9UQC7"	"Interconversion of nucleotide di- and triphosphates"	""	"1"	"0"	"71.8"	"86.7"	"344.4"	"94.0"	"101.1"	"66.3"	"448.7"	"54.3"	"68.7"	"70.4"	"64.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01968"	"Inositol polyphosphate 5-phosphatase OCRL OS=Homo sapiens OX=9606 GN=OCRL PE=1 SV=3"	"1"	"1"	"2"	"1"	"901"	"104.1"	"6.55"	"259.14"	"2.19"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00620, Pf03372, Pf16726"	"4952"	"ENSG00000122126"	"OCRL"	"A6NKI1; A8KAP2; B7ZLX2; hsa:4952; O60800; Q01968; Q15684; Q15774; Q4VY09; Q4VY10; Q5JQF1; Q5JQF2; Q9UJG5; Q9UMA5"	"Clathrin-mediated endocytosis; RAC3 GTPase cycle; RHOJ GTPase cycle; Golgi Associated Vesicle Biogenesis; Synthesis of PIPs at the plasma membrane; Synthesis of PIPs at the Golgi membrane; Synthesis of IP2, IP, and Ins in the cytosol; Synthesis of IP3 and IP4 in the cytosol"	"VEGFA-VEGFR2 signaling; Ciliopathies; Bardet-Biedl syndrome"	"11"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63165"	"Small ubiquitin-related modifier 1 OS=Homo sapiens OX=9606 GN=SUMO1 PE=1 SV=1"	"14"	"2"	"2"	"2"	"101"	"11.6"	"5.52"	"251.30"	"2.19"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf11976"	"7341"	"ENSG00000116030"	"SUMO1"	"A8MUS8; B2R4I5; hsa:7341; P55856; P63165; Q6FGG0; Q6NZ62; Q93068"	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; SUMOylation of intracellular receptors; Regulation of IFNG signaling; SUMOylation of transcription factors; Postmitotic nuclear pore complex (NPC) reformation; Formation of Incision Complex in GG-NER; Negative regulation of activity of TFAP2 (AP-2) family transcription factors; Maturation of nucleoprotein; SUMOylation of immune response proteins; SUMOylation of nuclear envelope proteins; Maturation of nucleoprotein; SUMO is conjugated to E1 (UBA2:SAE1); SUMO is transferred from E1 to E2 (UBE2I, UBC9); SUMO is proteolytically processed"	"Androgen receptor signaling pathway; TP53 network; Exercise-induced circadian regulation"	"25"	"0"	"235.6"	"267.4"	"785.3"	"262.5"	"295.6"	"207.8"	"1177.6"	"160.5"	"283.5"	"221.6"	"199.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IVL6"	"Prolyl 3-hydroxylase 3 OS=Homo sapiens OX=9606 GN=P3H3 PE=1 SV=1"	"3"	"1"	"1"	"1"	"736"	"81.8"	"6.32"	""	"2.19"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"ER/Golgi;other cell component"	"other molecular function"	"Pf13640"	"10536"	"ENSG00000110811"	"P3H3"	"hsa:10536; Q13512; Q15740; Q66K32; Q6NX61; Q7L2T1; Q8IVL6"	"Collagen biosynthesis and modifying enzymes"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"A8MWD9"	"Putative small nuclear ribonucleoprotein G-like protein 15 OS=Homo sapiens OX=9606 GN=SNRPGP15 PE=5 SV=2"	"9"	"1"	"2"	"1"	"76"	"8.5"	"8.84"	"257.19"	"2.18"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf01423"	""	""	"SNRPGP15"	"A8MWD9"	""	""	"0"	"0"	"137.1"	"138.8"	"413.8"	"158.5"	"158.8"	"126.0"	"511.3"	"83.6"	"116.4"	"101.6"	"85.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UPR3"	"Protein SMG5 OS=Homo sapiens OX=9606 GN=SMG5 PE=1 SV=3"	"1"	"1"	"1"	"1"	"1016"	"113.9"	"5.91"	""	"2.18"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf10373, Pf10374, Pf13638"	"23381"	"ENSG00000198952"	"SMG5"	"D3DVB7; hsa:23381; Q5QJE7; Q659C7; Q8IXC0; Q8IY09; Q96IJ7; Q9UPR3"	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"P62380"	"TATA box-binding protein-like protein 1 OS=Homo sapiens OX=9606 GN=TBPL1 PE=1 SV=1"	"6"	"1"	"2"	"1"	"186"	"20.9"	"9.54"	"272.18"	"2.18"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00352"	"9519"	"ENSG00000028839"	"TBPL1"	"A8K8F5; hsa:9519; O95753; P62380; Q9BWD5; Q9Z2Z0"	""	""	"0"	"0"	"13.2"	"7.3"	"57.3"	"13.7"	"9.9"	"11.0"	"54.5"	"9.4"	"14.1"	"7.4"	"6.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86V88"	"Magnesium-dependent phosphatase 1 OS=Homo sapiens OX=9606 GN=MDP1 PE=1 SV=1"	"8"	"1"	"2"	"1"	"176"	"20.1"	"6.39"	"264.66"	"2.18"	"1"	"1"	""	""	"other molecular function"	"Pf12689"	"145553"	"ENSG00000213920; ENSG00000285200"	"MDP1"	"hsa:145553; Q86V88; Q86Y84; Q8NAD9"	""	""	"0"	"0"	"9.8"	"11.3"	"32.7"	"8.7"	"14.9"	"11.5"	"43.2"	"5.9"	"6.2"	"12.0"	"9.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y6B7"	"AP-4 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP4B1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"739"	"83.2"	"5.86"	"251.46"	"2.18"	"1"	"1"	"transport;other biological processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle"	"other molecular function"	"Pf01602, Pf09066"	"10717"	"ENSG00000134262"	"AP4B1"	"B7Z4X3; hsa:10717; Q59EJ4; Q96CL6; Q9Y6B7"	"Golgi Associated Vesicle Biogenesis; Lysosome Vesicle Biogenesis"	""	"2"	"0"	"299.2"	"367.3"	"727.6"	"348.2"	"315.1"	"252.8"	"601.8"	"123.7"	"220.1"	"293.8"	"530.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14578"	"Citron Rho-interacting kinase OS=Homo sapiens OX=9606 GN=CIT PE=1 SV=2"	"1"	"1"	"2"	"1"	"2027"	"231.3"	"6.57"	"278.90"	"2.18"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069, Pf00169, Pf00780"	"11113"	"ENSG00000122966"	"CIT"	"hsa:11113; O14578; Q2M5E1; Q6XUH8; Q86UQ9; Q9UPZ7"	"RHOC GTPase cycle; RHOA GTPase cycle; RAC1 GTPase cycle; RHOB GTPase cycle; RHO GTPases activate CIT"	"Pleural mesothelioma; G13 signaling pathway"	"7"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q13616"	"Cullin-1 OS=Homo sapiens OX=9606 GN=CUL1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"776"	"89.6"	"8.00"	"307.46"	"2.18"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00888, Pf10557"	"8454"	"ENSG00000055130"	"CUL1"	"D3DWG3; hsa:8454; O60719; Q08AL6; Q13616; Q8IYW1"	"Nuclear events stimulated by ALK signaling in cancer; Circadian Clock; Antigen processing: Ubiquitination & Proteasome degradation; Regulation of PLK1 Activity at G2/M Transition; FCERI mediated NF-kB activation; Downstream TCR signaling; Activation of NF-kappaB in B cells; SCF-beta-TrCP mediated degradation of Emi1; Degradation of beta-catenin by the destruction complex; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; NIK-->noncanonical NF-kB signaling; Orc1 removal from chromatin; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Neddylation; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; SCF(Skp2)-mediated degradation of p27/p21; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Cyclin D associated events in G1; Regulation of BACH1 activity; MAP3K8 (TPL2)-dependent MAPK1/3 activation; NOTCH1 Intracellular Domain Regulates Transcription; Prolactin receptor signaling; Iron uptake and transport; Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling"	"Cell cycle; TNF-alpha signaling pathway; Parkin-ubiquitin proteasomal system pathway; Apoptosis-related network due to altered Notch3 in ovarian cancer; Glucocorticoid receptor pathway; Nuclear receptors meta-pathway; Pleural mesothelioma; Notch signaling pathway"	"40"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NYA1"	"Sphingosine kinase 1 OS=Homo sapiens OX=9606 GN=SPHK1 PE=1 SV=1"	"2"	"1"	"1"	"1"	"384"	"42.5"	"7.11"	""	"2.17"	""	"1"	"cell cycle OR cell proliferation;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00781"	"8877"	"ENSG00000176170"	"SPHK1"	"hsa:8877; Q8N632; Q96GK1; Q9HD92; Q9NY70; Q9NYA1; Q9NYL3"	"Extra-nuclear estrogen signaling; Association of TriC/CCT with target proteins during biosynthesis; Sphingolipid de novo biosynthesis; VEGFR2 mediated cell proliferation"	"Sphingolipid pathway; S1P receptor signal transduction; Metabolism of sphingolipids in ER and Golgi apparatus; Sphingolipid metabolism: integrated pathway; Sphingolipid metabolism in senescence; GDNF signaling; Biosynthesis and turnover of 1-deoxy-sphingoid bases; Synthesis of ceramides and 1-deoxyceramides"	"12"	"0"	"94.3"	"99.3"	"336.6"	"101.9"	"107.5"	"75.1"	"602.8"	"109.3"	"234.3"	"260.4"	"225.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62328"	"Thymosin beta-4 OS=Homo sapiens OX=9606 GN=TMSB4X PE=1 SV=2"	"32"	"2"	"3"	"2"	"44"	"5.1"	"5.06"	"580.67"	"2.17"	"2"	"1"	"cell organization and biogenesis;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01290"	"7114"	"ENSG00000205542"	"TMSB4X"	"hsa:7114; P01253; P01254; P62328; Q546P5; Q63576; Q9UE55"	"Platelet degranulation"	"Genes targeted by miRNAs in adipocytes; VEGFA-VEGFR2 signaling; IL-18 signaling pathway; Regulation of actin cytoskeleton"	"5"	"0"	"194.4"	"180.4"	"1066.1"	"214.4"	"173.0"	"107.6"	"1566.3"	"118.5"	"147.3"	"104.4"	"60.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52888"	"Thimet oligopeptidase OS=Homo sapiens OX=9606 GN=THOP1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"689"	"78.8"	"6.05"	"312.37"	"2.17"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf01432"	"7064"	"ENSG00000172009"	"THOP1"	"B3KSE2; hsa:7064; P52888; Q9UCB3"	"Antigen processing: Ubiquitination & Proteasome degradation"	""	"1"	"0"	"84.3"	"114.4"	"539.4"	"122.5"	"85.9"	"66.8"	"807.7"	"85.3"	"93.5"	"63.9"	"64.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35080"	"Profilin-2 OS=Homo sapiens OX=9606 GN=PFN2 PE=1 SV=3"	"7"	"1"	"2"	"1"	"140"	"15.0"	"6.99"	"293.15"	"2.17"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00235"	"5217"	"ENSG00000070087"	"PFN2"	"B2R4C8; D3DNI4; hsa:5217; P35080; Q4VBQ4; Q8WVF9; Q9HBK2"	"RHO GTPases Activate Formins; Signaling by ROBO receptors"	"Physico-chemical features and toxicity-associated pathways"	"3"	"0"	"48.2"	"39.2"	"141.4"	"49.0"	"45.7"	"40.7"	"177.5"	"38.1"	"55.4"	"57.1"	"68.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UID3"	"Vacuolar protein sorting-associated protein 51 homolog OS=Homo sapiens OX=9606 GN=VPS51 PE=1 SV=2"	"3"	"2"	"3"	"2"	"782"	"86.0"	"6.47"	"574.47"	"2.17"	"2"	"1"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	""	"Pf15469"	"738"	"ENSG00000149823"	"VPS51"	"hsa:738; Q6PJV5; Q7L8A6; Q8WZ35; Q96DF4; Q96GR3; Q9UID3"	"Retrograde transport at the Trans-Golgi-Network"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"P57105"	"Synaptojanin-2-binding protein OS=Homo sapiens OX=9606 GN=SYNJ2BP PE=1 SV=2"	"7"	"1"	"1"	"1"	"145"	"15.9"	"6.30"	""	"2.17"	""	"1"	"transport;signal transduction;other biological processes"	"other membranes;mitochondrion"	""	"Pf00595"	"55333"	"ENSG00000213463"	"SYNJ2BP"	"hsa:55333; P57105; Q49SH3; Q96IA4"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q8WWF5"	"E3 ubiquitin-protein ligase ZNRF4 OS=Homo sapiens OX=9606 GN=ZNRF4 PE=1 SV=3"	"1"	"1"	"2"	"1"	"429"	"46.9"	"7.99"	"255.63"	"2.17"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02225, Pf13639"	"148066"	"ENSG00000105428"	"ZNRF4"	"A8K886; hsa:148066; O75866; Q8WWF5"	""	""	"0"	"0"	"18.4"	"17.0"	"42.5"	"10.5"	"8.1"	"6.3"	"48.4"	"17.2"	"21.9"	"16.1"	"38.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P68402"	"Platelet-activating factor acetylhydrolase IB subunit beta OS=Homo sapiens OX=9606 GN=PAFAH1B2 PE=1 SV=1"	"4"	"1"	"2"	"1"	"229"	"25.6"	"5.92"	"289.38"	"2.17"	"1"	"1"	"other metabolic processes;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf13472"	"5049"	"ENSG00000168092"	"PAFAH1B2"	"A8DPS5; A8DPS6; A8DPS7; E9PEJ5; E9PLP3; hsa:5049; O00687; P68402; Q29459; Q6IBR6"	"Neutrophil degranulation; COPI-independent Golgi-to-ER retrograde traffic"	""	"2"	"0"	"59.2"	"72.7"	"319.4"	"77.5"	"65.7"	"44.8"	"294.9"	"56.2"	"61.2"	"41.7"	"22.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95721"	"Synaptosomal-associated protein 29 OS=Homo sapiens OX=9606 GN=SNAP29 PE=1 SV=1"	"7"	"2"	"3"	"2"	"258"	"29.0"	"5.81"	"556.60"	"2.17"	"2"	"1"	"cell-cell signaling;cell organization and biogenesis;other metabolic processes;transport"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	""	"9342"	"ENSG00000099940"	"SNAP29"	"hsa:9342; O95721"	"Neutrophil degranulation; Intra-Golgi traffic"	"Ciliary landscape; 22q11.2 copy number variation syndrome"	"4"	"0"	"38.5"	"51.8"	"149.4"	"54.6"	"64.7"	"41.2"	"176.0"	"35.4"	"55.2"	"49.9"	"63.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43572"	"A-kinase anchor protein 10, mitochondrial OS=Homo sapiens OX=9606 GN=AKAP10 PE=1 SV=2"	"2"	"1"	"2"	"1"	"662"	"73.8"	"6.39"	"268.06"	"2.16"	"1"	"1"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00615"	"11216"	"ENSG00000108599"	"AKAP10"	"B2R650; hsa:11216; O43572; Q96AJ7"	"Factors involved in megakaryocyte development and platelet production"	"G protein signaling pathways"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5L0"	"Transportin-3 OS=Homo sapiens OX=9606 GN=TNPO3 PE=1 SV=3"	"1"	"1"	"2"	"1"	"923"	"104.1"	"5.57"	"262.32"	"2.16"	"1"	"1"	"transport"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf08389"	"23534"	"ENSG00000064419"	"TNPO3"	"A4D1K9; C9IZM0; hsa:23534; Q6NUM1; Q96G71; Q96GU9; Q9Y3R2; Q9Y5L0"	""	""	"0"	"0"	"9.7"	"10.3"	"49.3"	"9.3"	"8.5"	"7.4"	"34.4"	"2.0"	"10.1"	"5.1"	"6.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15811"	"Intersectin-1 OS=Homo sapiens OX=9606 GN=ITSN1 PE=1 SV=3"	"1"	"1"	"1"	"1"	"1721"	"195.3"	"7.77"	""	"2.16"	""	"1"	"transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00018, Pf00168, Pf00621, Pf07653, Pf12763, Pf14604, Pf16617, Pf16652"	"6453"	"ENSG00000205726"	"ITSN1"	"A7Y322; A8CTX8; A8CTY3; A8CTY7; A8D7D0; A8DCP3; B4DTM2; E7ERJ1; E9PE44; E9PG01; E9PHV2; hsa:6453; O95216; Q0PW94; Q0PW95; Q0PW97; Q14BD3; Q15811; Q1ED40; Q20BK3; Q9UET5; Q9UK60; Q9UNK1; Q9UNK2; Q9UQ92"	"EPHB-mediated forward signaling; Cargo recognition for clathrin-mediated endocytosis; RHOG GTPase cycle; G alpha (12/13) signalling events; CDC42 GTPase cycle; NRAGE signals death through JNK; RHOQ GTPase cycle"	""	"8"	"0"	"23.9"	"19.7"	"86.8"	"22.6"	"24.2"	"17.2"	"78.2"	"10.7"	"11.8"	"13.1"	"22.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5VZE5"	"N-alpha-acetyltransferase 35, NatC auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA35 PE=1 SV=1"	"2"	"1"	"2"	"1"	"725"	"83.6"	"7.05"	"254.52"	"2.16"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	""	"Pf04112"	"60560"	"ENSG00000135040"	"NAA35"	"hsa:60560; Q5VZE5; Q5VZE6; Q9H631; Q9H703"	"Retrograde transport at the Trans-Golgi-Network"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11717"	"Cation-independent mannose-6-phosphate receptor OS=Homo sapiens OX=9606 GN=IGF2R PE=1 SV=3"	"0"	"1"	"1"	"1"	"2491"	"274.2"	"5.94"	""	"2.16"	""	"1"	"transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf00040, Pf00878"	"3482"	"ENSG00000197081"	"IGF2R"	"hsa:3482; P11717; Q7Z7G9; Q96PT5"	"Neutrophil degranulation; Golgi Associated Vesicle Biogenesis; Cargo recognition for clathrin-mediated endocytosis; Retrograde transport at the Trans-Golgi-Network"	"TROP2 regulatory signaling"	"6"	"0"	"56.6"	"49.9"	"152.0"	"67.8"	"82.5"	"65.0"	"228.7"	"49.1"	"77.1"	"68.1"	"48.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9GZL7"	"Ribosome biogenesis protein WDR12 OS=Homo sapiens OX=9606 GN=WDR12 PE=1 SV=2"	"2"	"1"	"2"	"1"	"423"	"47.7"	"5.90"	"318.37"	"2.16"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00400, Pf08154"	"55759"	"ENSG00000138442"	"WDR12"	"B3KPA9; hsa:55759; Q96HU0; Q9GZL7; Q9NV80; Q9NYI8"	"Major pathway of rRNA processing in the nucleolus and cytosol"	""	"1"	"0"	"17.5"	"20.8"	"92.4"	"20.5"	"15.2"	"14.0"	"121.0"	"10.1"	"10.4"	"12.9"	"10.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6ZUS6"	"Coiled-coil domain-containing protein 149 OS=Homo sapiens OX=9606 GN=CCDC149 PE=2 SV=2"	"3"	"1"	"1"	"1"	"474"	"52.8"	"6.29"	""	"2.16"	""	"1"	""	""	""	"Pf09789"	"91050"	"ENSG00000181982"	"CCDC149"	"A6NJE7; B4DK90; B4DZG3; G5EA04; hsa:91050; Q6NW41; Q6ZUS6; Q8N3K8"	""	""	"0"	"0"	"88.8"	"123.2"	"496.5"	"113.1"	"86.5"	"69.0"	"642.8"	"54.7"	"77.7"	"53.4"	"57.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NWU2"	"Glucose-induced degradation protein 8 homolog OS=Homo sapiens OX=9606 GN=GID8 PE=1 SV=1"	"8"	"2"	"2"	"2"	"228"	"26.7"	"4.97"	"254.55"	"2.15"	"1"	"1"	"cell-cell signaling;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf08513, Pf10607"	"54994"	"ENSG00000101193"	"GID8"	"E1P5I3; hsa:54994; Q8N5M5; Q9NWU2"	""	"Ciliary landscape"	"1"	"0"	"16.0"	"18.4"	"82.4"	"17.0"	"22.7"	"12.7"	"103.3"	"10.8"	"9.9"	"6.8"	"9.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14997"	"Proteasome activator complex subunit 4 OS=Homo sapiens OX=9606 GN=PSME4 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1843"	"211.2"	"6.90"	"240.56"	"2.15"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf11919, Pf16507"	"23198"	"ENSG00000068878"	"PSME4"	"hsa:23198; Q14997; Q1XBG4; Q1XBG5; Q1XBG6; Q2M1Z0; Q6IPR2; Q86XF8"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway"	""	"52"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IWV8"	"E3 ubiquitin-protein ligase UBR2 OS=Homo sapiens OX=9606 GN=UBR2 PE=1 SV=1"	"1"	"1"	"1"	"1"	"1755"	"200.4"	"6.24"	""	"2.15"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf02207, Pf02617, Pf18995"	"23304"	"ENSG00000024048"	"UBR2"	"hsa:23304; O15057; Q4VXK2; Q5TFH6; Q6P2I2; Q6ZUD0; Q8IWV8"	"Antigen processing: Ubiquitination & Proteasome degradation"	"Male infertility; Primary ovarian insufficiency"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q12789"	"General transcription factor 3C polypeptide 1 OS=Homo sapiens OX=9606 GN=GTF3C1 PE=1 SV=4"	"2"	"3"	"3"	"3"	"2109"	"238.7"	"7.30"	"825.27"	"2.15"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04182"	"2975"	"ENSG00000077235"	"GTF3C1"	"B2RP21; hsa:2975; Q12789; Q12838; Q6DKN9; Q9Y4W9"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter"	""	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q00765"	"Receptor expression-enhancing protein 5 OS=Homo sapiens OX=9606 GN=REEP5 PE=1 SV=3"	"4"	"1"	"1"	"1"	"189"	"21.5"	"8.10"	""	"2.14"	""	"1"	"cell organization and biogenesis;other biological processes"	"other membranes;cytosol;ER/Golgi"	""	"Pf03134"	"7905"	"ENSG00000129625"	"REEP5"	"B7Z681; D3DT04; hsa:7905; Q00765; Q04198; Q5QGT0; Q9BWH9"	""	""	"0"	"0"	"57.4"	"35.2"	"175.9"	"33.3"	"27.9"	"15.5"	"253.7"	"11.7"	"6.2"	"24.0"	"9.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IXW5"	"Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 OS=Homo sapiens OX=9606 GN=RPAP2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"612"	"69.5"	"7.78"	"259.16"	"2.14"	"1"	"1"	"RNA metabolism OR transcription;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf04181"	"79871"	"ENSG00000122484"	"RPAP2"	"C9JKB5; hsa:79871; Q49AS7; Q8IXW5; Q9H8Y2"	"RNA polymerase II transcribes snRNA genes"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q96A49"	"Synapse-associated protein 1 OS=Homo sapiens OX=9606 GN=SYAP1 PE=1 SV=1"	"2"	"1"	"1"	"1"	"352"	"39.9"	"4.53"	""	"2.14"	""	"1"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	""	"Pf03909"	"94056"	"ENSG00000169895"	"SYAP1"	"hsa:94056; Q68CP1; Q96A49; Q96C60; Q96JQ6; Q96T20"	""	""	"0"	"0"	"168.7"	"143.1"	"426.0"	"172.6"	"156.6"	"126.2"	"451.8"	"94.6"	"144.5"	"108.2"	"116.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q969T7"	"7-methylguanosine phosphate-specific 5'-nucleotidase OS=Homo sapiens OX=9606 GN=NT5C3B PE=1 SV=4"	"6"	"1"	"1"	"1"	"300"	"34.4"	"6.38"	""	"2.13"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf05822"	"115024"	"ENSG00000141698"	"NT5C3B"	"A8MWB9; C9JKC4; hsa:115024; Q7L3B7; Q969T7"	"mRNA decay by 3' to 5' exoribonuclease"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"P10243"	"Myb-related protein A OS=Homo sapiens OX=9606 GN=MYBL1 PE=1 SV=2"	"1"	"1"	"1"	"1"	"752"	"85.8"	"7.12"	""	"2.13"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf07988, Pf09316, Pf13921"	"4603"	"ENSG00000185697"	"MYBL1"	"E7EW29; hsa:4603; P10243; Q495F9"	"PIWI-interacting RNA (piRNA) biogenesis"	"Pre-implantation embryo; Pathways affected in adenoid cystic carcinoma"	"3"	"0"	"178.5"	"180.9"	"823.5"	"168.9"	"97.0"	"75.8"	"749.8"	"31.1"	"62.6"	"43.6"	"46.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14197"	"Peptidyl-tRNA hydrolase ICT1, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL58 PE=1 SV=1"	"3"	"1"	"2"	"1"	"206"	"23.6"	"10.07"	"308.63"	"2.13"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"plasma membrane;other membranes;mitochondrion;translational apparatus;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00472"	"3396"	"ENSG00000167862"	"MRPL58"	"B2RAD1; hsa:3396; Q14197; Q53HM7; Q53Y11"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"205.4"	"210.5"	"567.7"	"197.0"	"182.8"	"150.8"	"586.6"	"92.3"	"151.6"	"134.6"	"182.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HCC9"	"Lateral signaling target protein 2 homolog OS=Homo sapiens OX=9606 GN=ZFYVE28 PE=1 SV=3"	"1"	"1"	"1"	"1"	"887"	"96.4"	"5.11"	""	"2.13"	""	"1"	"other biological processes"	"other membranes;cytosol;other cytoplasmic organelle"	"other molecular function"	"Pf01363"	"57732"	"ENSG00000159733"	"ZFYVE28"	"B2RP83; B3KX50; B7Z1Q7; B7Z2G9; B7Z2M2; B7ZB19; E9PB54; E9PB64; E9PG77; hsa:57732; Q7Z6J3; Q9HCC9"	""	""	"0"	"0"	"102.4"	"81.1"	"988.5"	"192.6"	"110.4"	"68.8"	"1220.1"	"33.5"	"52.0"	"36.8"	"26.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P41227"	"N-alpha-acetyltransferase 10 OS=Homo sapiens OX=9606 GN=NAA10 PE=1 SV=1"	"15"	"2"	"3"	"2"	"235"	"26.4"	"5.64"	"511.13"	"2.13"	"2"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00583"	"8260"	"ENSG00000102030"	"NAA10"	"A6NM98; hsa:8260; P41227"	""	""	"0"	"0"	"13.7"	"15.1"	"39.9"	"11.2"	"8.6"	"5.0"	"20.2"	"8.4"	"10.3"	"8.9"	"12.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P34995"	"Prostaglandin E2 receptor EP1 subtype OS=Homo sapiens OX=9606 GN=PTGER1 PE=2 SV=3"	"7"	"1"	"1"	"1"	"402"	"41.8"	"11.72"	""	"2.13"	""	"1"	"stress response;signal transduction;other biological processes"	"plasma membrane;other membranes"	"signal transduction activity or receptor binding;other molecular function"	"Pf00001"	"5731"	"ENSG00000160951"	"PTGER1"	"hsa:5731; P34995; Q5U5U4; Q86UH3; Q86VB5; Q8NHB2"	"G alpha (q) signalling events; Prostanoid ligand receptors"	"Small ligand GPCRs; Relationship between inflammation, COX-2 and EGFR; GPCRs, class A rhodopsin-like; Prostaglandin and leukotriene metabolism in senescence ; Prostaglandin and leukotriene metabolism in senescence ; Prostaglandin synthesis and regulation"	"8"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BRJ7"	"Tudor-interacting repair regulator protein OS=Homo sapiens OX=9606 GN=NUDT16L1 PE=1 SV=1"	"5"	"1"	"2"	"1"	"211"	"23.3"	"8.91"	"242.86"	"2.13"	"1"	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity"	""	"84309"	"ENSG00000168101"	"NUDT16L1"	"hsa:84309; Q8NAI2; Q9BRJ7"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q13490"	"Baculoviral IAP repeat-containing protein 2 OS=Homo sapiens OX=9606 GN=BIRC2 PE=1 SV=2"	"1"	"1"	"1"	"1"	"618"	"69.9"	"6.70"	""	"2.12"	""	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00619, Pf00653, Pf13920"	"329"	"ENSG00000110330"	"BIRC2"	"B4E026; hsa:329; Q13490; Q16516; Q4TTG0"	"Ub-specific processing proteases; Regulation of TNFR1 signaling; TNFR1-induced NF-kappa-B signaling pathway; IKK complex recruitment mediated by RIP1; Regulation of necroptotic cell death; TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway; NOD1/2 Signaling Pathway; TICAM1, RIP1-mediated IKK complex recruitment; TNFR1-induced proapoptotic signaling; Apoptotic cleavage of cellular proteins"	"TNF-related weak inducer of apoptosis (TWEAK) signaling pathway; TNF-alpha signaling pathway; Apoptosis; Glucocorticoid receptor pathway; Nuclear receptors meta-pathway; Focal adhesion; Photodynamic therapy-induced NF-kB survival signaling; Small cell lung cancer; Gastrin signaling pathway; Head and neck squamous cell carcinoma; 11p11.2 copy number variation syndrome"	"23"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7L1Q6"	"Basic leucine zipper and W2 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=BZW1 PE=1 SV=1"	"6"	"4"	"6"	"2"	"419"	"48.0"	"5.92"	"1304.01"	"2.12"	"4"	"1"	"other biological processes"	"other cell component"	""	"Pf02020"	"9689"	"ENSG00000082153"	"BZW1"	"B4DLZ8; B4DWF7; hsa:9689; Q14281; Q15394; Q7L1Q6; Q9BUY0"	""	""	"0"	"2"	"589.8"	"545.5"	"2357.4"	"487.9"	"304.4"	"231.9"	"2036.9"	"142.9"	"226.0"	"187.1"	"195.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y6E2"	"Basic leucine zipper and W2 domain-containing protein 2 OS=Homo sapiens OX=9606 GN=BZW2 PE=1 SV=1"	"5"	"3"	"4"	"1"	"419"	"48.1"	"6.68"	"796.41"	"2.12"	"3"	"1"	"other biological processes"	"other cell component"	""	"Pf02020"	"28969"	"ENSG00000136261"	"BZW2"	"A4D123; hsa:28969; Q3B779; Q96JW5; Q9H3F7; Q9Y6E2"	""	""	"0"	"0"	"74.7"	"79.9"	"351.0"	"77.6"	"84.3"	"46.1"	"350.9"	"28.3"	"40.2"	"36.0"	"33.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P41214"	"Eukaryotic translation initiation factor 2D OS=Homo sapiens OX=9606 GN=EIF2D PE=1 SV=3"	"2"	"1"	"1"	"1"	"584"	"64.7"	"7.65"	""	"2.12"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01253, Pf17832"	"1939"	"ENSG00000143486"	"EIF2D"	"hsa:1939; P41214; Q5SY40; Q8IXV3; Q96DG3; Q96TG7; Q9NR27; Q9NSN0; Q9NV18; Q9NZ21"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"n/a"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"P62854"	"40S ribosomal protein S26 OS=Homo sapiens OX=9606 GN=RPS26 PE=1 SV=3"	"8"	"1"	"2"	"1"	"115"	"13.0"	"11.00"	"243.93"	"2.12"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01283"	"6231"	"ENSG00000197728"	"RPS26"	"hsa:6231; P02383; P62854; P70394; Q06722; Q3MHD8; Q6IRY4"	"Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Peptide chain elongation; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9NVS2"	"39S ribosomal protein S18a, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS18A PE=1 SV=1"	"5"	"1"	"2"	"1"	"196"	"22.2"	"10.33"	"284.93"	"2.12"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf01084"	"55168"	"ENSG00000096080"	"MRPS18A"	"A6XND3; hsa:55168; Q5QPA4; Q9NVS2"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"62.9"	"68.7"	"201.6"	"57.9"	"55.3"	"45.6"	"218.5"	"32.0"	"48.1"	"37.9"	"44.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15291"	"Retinoblastoma-binding protein 5 OS=Homo sapiens OX=9606 GN=RBBP5 PE=1 SV=2"	"2"	"1"	"2"	"1"	"538"	"59.1"	"5.10"	"280.21"	"2.12"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00400"	"5929"	"ENSG00000117222"	"RBBP5"	"A8K272; hsa:5929; Q15291; Q7Z6D8; Q8NDZ7"	"Neddylation; Formation of WDR5-containing histone-modifying complexes; Formation of the beta-catenin:TCF transactivating complex; Deactivation of the beta-catenin transactivating complex; Activation of anterior HOX genes in hindbrain development during early embryogenesis; PKMTs methylate histone lysines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"	"Kleefstra syndrome"	"8"	"0"	"6.6"	"7.4"	"54.8"	"4.1"	"4.8"	"5.4"	"66.1"	"4.4"	"6.1"	"6.9"	"6.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51178"	"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 OS=Homo sapiens OX=9606 GN=PLCD1 PE=1 SV=2"	"2"	"1"	"1"	"1"	"756"	"85.6"	"6.70"	""	"2.11"	""	"1"	"other metabolic processes;transport;signal transduction"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00168, Pf00387, Pf00388, Pf09279"	"5333"	"ENSG00000187091"	"PLCD1"	"B3KR14; hsa:5333; P51178; Q86VN8"	"Synthesis of IP3 and IP4 in the cytosol"	"Myometrial relaxation and contraction pathways; GPR40 pathway; Non-genomic actions of 1,25 dihydroxyvitamin D3; Resistin as a regulator of inflammation; Orexin receptor pathway"	"6"	"0"	"405.3"	"244.7"	"138.2"	"33.8"	"27.7"	"27.7"	"75.4"	"26.9"	"19.9"	"18.7"	"23.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7L5Y9"	"E3 ubiquitin-protein transferase MAEA OS=Homo sapiens OX=9606 GN=MAEA PE=1 SV=1"	"4"	"1"	"1"	"1"	"396"	"45.3"	"8.69"	""	"2.11"	""	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf10607"	"10296"	"ENSG00000090316"	"MAEA"	"hsa:10296; O95285; Q5JB54; Q6ZRD6; Q7L5Y9; Q9BQ11; Q9H9V6; Q9H9Z4; Q9NW84"	""	"Ciliary landscape"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q86UZ6"	"Zinc finger and BTB domain-containing protein 46 OS=Homo sapiens OX=9606 GN=ZBTB46 PE=1 SV=2"	"2"	"1"	"1"	"1"	"589"	"64.0"	"5.87"	""	"2.11"	""	"1"	"RNA metabolism OR transcription;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00651, Pf13909"	"140685"	"ENSG00000130584"	"ZBTB46"	"E1P5K9; hsa:140685; Q5JWJ3; Q6GMV4; Q86UZ6; Q9BQK3; Q9H3Z8; Q9H3Z9"	""	""	"0"	"0"	"88.0"	"92.0"	"667.5"	"183.2"	"119.2"	"111.2"	"650.7"	"38.6"	"106.1"	"73.8"	"82.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75446"	"Histone deacetylase complex subunit SAP30 OS=Homo sapiens OX=9606 GN=SAP30 PE=1 SV=1"	"5"	"1"	"2"	"1"	"220"	"23.3"	"9.17"	"233.50"	"2.11"	"1"	"1"	"RNA metabolism OR transcription;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf13866, Pf13867"	"8819"	"ENSG00000164105"	"SAP30"	"D3DP38; hsa:8819; O75446"	"Potential therapeutics for SARS; HDACs deacetylate histones; NoRC negatively regulates rRNA expression"	"Retinoblastoma gene in cancer; Notch signaling pathway"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55010"	"Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2"	"3"	"1"	"2"	"1"	"431"	"49.2"	"5.58"	"246.55"	"2.11"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf01873, Pf02020"	"1983"	"ENSG00000100664"	"EIF5"	"hsa:1983; P55010; Q53XB3; Q9H5N2; Q9UG48"	"Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"O43683"	"Mitotic checkpoint serine/threonine-protein kinase BUB1 OS=Homo sapiens OX=9606 GN=BUB1 PE=1 SV=1"	"1"	"1"	"1"	"1"	"1085"	"122.3"	"6.47"	""	"2.11"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf08311"	"699"	"ENSG00000169679"	"BUB1"	"E9PC26; F5GXI5; hsa:699; O43430; O43643; O43683; O60626; Q53QE4"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"Cell cycle; ATM signaling in development and disease ; Regulation of sister chromatid separation at the metaphase-anaphase transition"	"9"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15049"	"Membrane protein MLC1 OS=Homo sapiens OX=9606 GN=MLC1 PE=1 SV=5"	"4"	"1"	"1"	"1"	"377"	"41.1"	"7.49"	""	"2.10"	""	"1"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	""	"23209"	"ENSG00000100427"	"MLC1"	"B3KW61; B7Z659; hsa:23209; Q15049; Q5JZ83; Q8TAG4; Q96RP5; Q9UGY8"	""	""	"0"	"0"	"25.3"	"17.5"	"120.2"	"42.1"	"37.4"	"19.5"	"105.9"	"10.0"	"21.3"	"14.5"	"8.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09234"	"U1 small nuclear ribonucleoprotein C OS=Homo sapiens OX=9606 GN=SNRPC PE=1 SV=1"	"8"	"1"	"2"	"1"	"159"	"17.4"	"9.67"	"276.33"	"2.10"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf06220"	"6631"	"ENSG00000124562"	"SNRPC"	"hsa:6631; P09234; Q5TAL3"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"48.2"	"46.1"	"174.6"	"45.1"	"40.9"	"27.3"	"193.9"	"29.2"	"39.6"	"29.6"	"38.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60447"	"Ecotropic viral integration site 5 protein homolog OS=Homo sapiens OX=9606 GN=EVI5 PE=1 SV=3"	"2"	"1"	"2"	"1"	"810"	"92.9"	"6.10"	"375.77"	"2.10"	"1"	"1"	"cell cycle OR cell proliferation;transport;other biological processes"	"cytosol;cytoskeleton;nucleus"	"enzyme regulator activity;other molecular function"	"Pf00566"	"7813"	"ENSG00000067208"	"EVI5"	"A6NKX8; B9A6J0; hsa:7813; O60447; Q9H1Y9"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"O14617"	"AP-3 complex subunit delta-1 OS=Homo sapiens OX=9606 GN=AP3D1 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1153"	"130.1"	"8.48"	"283.12"	"2.10"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf01602, Pf06375"	"8943"	"ENSG00000065000"	"AP3D1"	"hsa:8943; O00202; O14617; O75262; Q59HF5; Q96G11; Q9H3C6"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3P9"	"Rab GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RABGAP1 PE=1 SV=3"	"1"	"1"	"2"	"1"	"1069"	"121.7"	"5.25"	"257.73"	"2.10"	"1"	"1"	"cell cycle OR cell proliferation;other biological processes"	"cytosol;cytoskeleton"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00566, Pf00640, Pf12473"	"23637"	"ENSG00000011454"	"RABGAP1"	"B9A6L2; hsa:23637; Q05CW2; Q6ZMY1; Q9HA28; Q9P0E2; Q9UG67; Q9Y3P9"	"TBC/RABGAPs"	""	"1"	"0"	"11.6"	"8.7"	"32.8"	"10.6"	"10.1"	"8.3"	"30.3"	"3.9"	"5.5"	"8.6"	"4.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51956"	"Serine/threonine-protein kinase Nek3 OS=Homo sapiens OX=9606 GN=NEK3 PE=1 SV=2"	"2"	"1"	"2"	"1"	"506"	"57.7"	"7.17"	"240.32"	"2.09"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"4752"	"ENSG00000136098"	"NEK3"	"A8K2J4; hsa:4752; P51956; Q5TAP2; Q8J023; Q8WUN5"	""	"Prolactin signaling pathway"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13418"	"Integrin-linked protein kinase OS=Homo sapiens OX=9606 GN=ILK PE=1 SV=2"	"2"	"1"	"2"	"1"	"452"	"51.4"	"8.07"	"245.56"	"2.09"	"1"	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf07714, Pf12796"	"3611"	"ENSG00000166333"	"ILK"	"B7Z1I0; B7Z418; D3DQU0; hsa:3611; P57043; Q13418; Q68DZ3"	"Localization of the PINCH-ILK-PARVIN complex to focal adhesions"	"Integrin-mediated cell adhesion; Primary focal segmental glomerulosclerosis (FSGS); Focal adhesion; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; PPAR signaling pathway; Eukaryotic transcription initiation; Endometrial cancer; Acute viral myocarditis; Genes controlling nephrogenesis; Development of ureteric collection system; 2q37 copy number variation syndrome"	"13"	"0"	"22.8"	"18.2"	"67.7"	"11.5"	"17.9"	"14.8"	"48.8"	"7.9"	"11.2"	"10.0"	"9.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31327"	"Carbamoyl-phosphate synthase [ammonia], mitochondrial OS=Homo sapiens OX=9606 GN=CPS1 PE=1 SV=2"	"1"	"1"	"1"	"1"	"1500"	"164.8"	"6.74"	""	"2.09"	""	"1"	"other metabolic processes;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00117, Pf00988, Pf02142, Pf02786, Pf02787"	"1373"	"ENSG00000021826"	"CPS1"	"B7Z818; hsa:1373; J3KQL0; O43774; P31327; Q53TL5; Q59HF8; Q7Z5I5"	"Urea cycle"	"Amino acid metabolism"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UF33"	"Ephrin type-A receptor 6 OS=Homo sapiens OX=9606 GN=EPHA6 PE=2 SV=3"	"1"	"1"	"1"	"1"	"1036"	"116.3"	"6.98"	""	"2.09"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction"	"plasma membrane;other membranes;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00041, Pf00536, Pf01404, Pf07699, Pf07714, Pf14575"	"285220"	"ENSG00000080224"	"EPHA6"	"D6RAL5; hsa:285220; Q9UF33"	"EPH-ephrin mediated repulsion of cells; EPHA-mediated growth cone collapse"	""	"3"	"0"	"70.7"	"67.1"	"160.6"	"75.4"	"93.9"	"87.2"	"167.6"	"54.6"	"80.3"	"108.9"	"57.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75436"	"Vacuolar protein sorting-associated protein 26A OS=Homo sapiens OX=9606 GN=VPS26A PE=1 SV=2"	"4"	"2"	"2"	"2"	"327"	"38.1"	"6.57"	"231.75"	"2.09"	"1"	"1"	"transport;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	""	"Pf03643"	"9559"	"ENSG00000122958"	"VPS26A"	"A8MZ56; B2RDD3; hsa:9559; O75436; Q8TBH4; Q9H982"	"WNT ligand biogenesis and trafficking"	""	"1"	"0"	"174.7"	"165.2"	"727.6"	"171.9"	"161.3"	"126.0"	"805.1"	"107.2"	"163.9"	"153.7"	"100.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NCM8"	"Cytoplasmic dynein 2 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC2H1 PE=1 SV=4"	"1"	"3"	"3"	"3"	"4307"	"492.3"	"6.54"	"491.42"	"2.09"	"2"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03028, Pf08385, Pf08393, Pf12774, Pf12775, Pf12777, Pf12780, Pf12781, Pf18198, Pf18199"	"79659"	"ENSG00000187240"	"DYNC2H1"	"hsa:79659; O00432; Q16693; Q3C1U8; Q4AC93; Q6ZMX7; Q6ZUM6; Q7Z363; Q8N977; Q8NCM8; Q92815; Q9HAE4"	"Hedgehog 'off' state; Intraflagellar transport"	"Intraflagellar transport proteins binding to dynein; Genes related to primary cilium development (based on CRISPR); Ciliopathies; 3q29 copy number variation syndrome; Bardet-Biedl syndrome"	"7"	"0"	"40.2"	"33.9"	"99.8"	"36.6"	"39.8"	"25.6"	"82.2"	"21.2"	"28.1"	"28.9"	"20.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NR33"	"DNA polymerase epsilon subunit 4 OS=Homo sapiens OX=9606 GN=POLE4 PE=1 SV=2"	"15"	"2"	"2"	"2"	"117"	"12.2"	"4.92"	"269.28"	"2.08"	"1"	"1"	"DNA metabolism;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00808"	"56655"	"ENSG00000115350"	"POLE4"	"hsa:56655; Q53TR2; Q9NR33"	"Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Dual Incision in GG-NER; Activation of the pre-replicative complex; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; DNA replication initiation; Gap-filling DNA repair synthesis and ligation in GG-NER"	"Pyrimidine metabolism; Base excision repair; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"16"	"0"	"166.4"	"233.4"	"663.6"	"221.4"	"231.2"	"183.4"	"1462.2"	"166.3"	"258.6"	"267.7"	"356.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96SB4"	"SRSF protein kinase 1 OS=Homo sapiens OX=9606 GN=SRPK1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"655"	"74.3"	"6.16"	"262.16"	"2.08"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"6732"	"ENSG00000096063"	"SRPK1"	"B4DS61; hsa:6732; Q12890; Q5R364; Q5R365; Q8IY12; Q96SB4"	"Maturation of nucleoprotein"	"VEGFA-VEGFR2 signaling; mRNA processing"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14654"	"Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1257"	"133.7"	"8.44"	"242.67"	"2.08"	"1"	"1"	"signal transduction"	"plasma membrane;other membranes;cytosol"	"signal transduction activity or receptor binding;other molecular function"	"Pf02174"	"8471"	"ENSG00000133124"	"IRS4"	"hsa:8471; O14654"	"IRS-related events triggered by IGF1R"	"Alzheimer's disease and miRNA effects; Adipogenesis; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Leptin-insulin signaling overlap; Insulin signaling; Alzheimer's disease"	"8"	"0"	"48.8"	"36.1"	"141.2"	"44.6"	"41.7"	"48.4"	"130.3"	"20.6"	"59.6"	"37.2"	"36.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BRJ2"	"39S ribosomal protein L45, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL45 PE=1 SV=2"	"3"	"1"	"1"	"1"	"306"	"35.3"	"9.03"	""	"2.08"	""	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	""	"Pf04280"	""	"ENSG00000277936"	"MRPL45"	"A1L436; Q6ZMJ5; Q9BRJ2"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"41.9"	"39.9"	"129.0"	"39.1"	"35.9"	"29.8"	"120.2"	"25.0"	"33.9"	"37.4"	"44.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96BN8"	"Ubiquitin thioesterase otulin OS=Homo sapiens OX=9606 GN=OTULIN PE=1 SV=3"	"4"	"1"	"1"	"1"	"352"	"40.2"	"5.47"	""	"2.08"	""	"1"	"cell-cell signaling;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf16218"	"90268"	"ENSG00000154124"	"OTULIN"	"D3DTD3; hsa:90268; Q8NAS0; Q96BN8; Q96IA3"	"Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Regulation of TNFR1 signaling"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63172"	"Dynein light chain Tctex-type 1 OS=Homo sapiens OX=9606 GN=DYNLT1 PE=1 SV=1"	"9"	"1"	"1"	"1"	"113"	"12.4"	"5.08"	""	"2.08"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"non-structural extracellular;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf03645"	"6993"	"ENSG00000146425"	"DYNLT1"	"hsa:6993; P63172; Q15763; Q5VTU4"	"Neutrophil degranulation"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein; Genes related to primary cilium development (based on CRISPR); 3q29 copy number variation syndrome"	"5"	"0"	"11.8"	"12.2"	"37.5"	"7.2"	"13.3"	"8.8"	"33.9"	"5.1"	"9.3"	"9.9"	"6.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5U4P2"	"Aspartate beta-hydroxylase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ASPHD1 PE=1 SV=3"	"4"	"1"	"1"	"1"	"390"	"41.1"	"8.56"	""	"2.08"	""	"1"	"protein metabolism;other metabolic processes"	"other membranes"	"other molecular function"	"Pf05118"	"253982"	"ENSG00000174939"	"ASPHD1"	"A0AVE3; B7ZLZ3; hsa:253982; Q5U4P2; Q8IW63; Q8N316; Q96H00"	""	"16p11.2 proximal deletion syndrome"	"1"	"0"	"75.8"	"81.1"	"341.7"	"92.3"	"71.5"	"59.3"	"312.7"	"37.4"	"63.5"	"50.4"	"56.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07311"	"Acylphosphatase-1 OS=Homo sapiens OX=9606 GN=ACYP1 PE=1 SV=2"	"10"	"1"	"2"	"1"	"99"	"11.3"	"9.31"	"237.07"	"2.07"	"1"	"1"	"other metabolic processes"	""	"other molecular function"	"Pf00708"	"97"	"ENSG00000119640"	"ACYP1"	"A6NDV8; B2R590; hsa:97; P07311"	""	""	"0"	"0"	"37.4"	"42.9"	"104.5"	"32.6"	"35.9"	"31.2"	"111.0"	"25.6"	"38.8"	"32.7"	"76.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P42345"	"Serine/threonine-protein kinase mTOR OS=Homo sapiens OX=9606 GN=MTOR PE=1 SV=1"	"0"	"1"	"2"	"1"	"2549"	"288.7"	"7.17"	"302.04"	"2.07"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;mitochondrion;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"translation activity;nucleic acid binding activity;kinase activity;other molecular function"	"Pf00454, Pf02259, Pf02260, Pf08771, Pf11865"	"2475"	"ENSG00000198793"	"MTOR"	"hsa:2475; P42345; Q4LE76; Q5TER1; Q6LE87; Q96QG3; Q9Y4I3"	"HSF1-dependent transactivation; Energy dependent regulation of mTOR by LKB1-AMPK; Amino acids regulate mTORC1; Constitutive Signaling by AKT1 E17K in Cancer; PIP3 activates AKT signaling; Regulation of TP53 Degradation; Regulation of PTEN gene transcription; mTORC1-mediated signalling; CD28 dependent PI3K/Akt signaling; TP53 Regulates Metabolic Genes; VEGFR2 mediated vascular permeability; Macroautophagy"	"AMP-activated protein kinase signaling; Target of rapamycin signaling; MicroRNAs in cardiomyocyte hypertrophy; Type II diabetes mellitus; Sterol regulatory element-binding proteins (SREBP) signaling; SREBF and miR33 in cholesterol and lipid homeostasis; RANKL/RANK signaling pathway; Thyroid stimulating hormone (TSH) signaling pathway; Leptin signaling pathway; Follicle stimulating hormone (FSH) signaling pathway; Prolactin signaling pathway; Alzheimer's disease and miRNA effects; Thymic stromal lymphopoietin (TSLP) signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Alpha 6 beta 4 signaling pathway; Cardiac hypertrophic response; Extracellular vesicle-mediated signaling in recipient cells; TSLP signaling pathway; Ovarian infertility; MECP2 and associated Rett syndrome; Wnt signaling pathway; BDNF-TrkB signaling; PI3K-AKT-mTOR signaling pathway and therapeutic opportunities; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; ATM signaling in development and disease ; 4-hydroxytamoxifen, dexamethasone, and retinoic acids regulation of p27 expression; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Embryonic stem cell pluripotency pathways; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Clear cell renal cell carcinoma pathways; PI3K/AKT/mTOR - vitamin D3 signaling; PI3K-Akt signaling pathway; Somatroph axis (GH) and its relationship to dietary restriction and aging; Caloric restriction and aging; Breast cancer pathway; Pancreatic adenocarcinoma pathway; Thermogenesis; EGF/EGFR signaling pathway; Synaptic signaling pathways associated with autism spectrum disorder; Hippo signaling regulation pathways; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Joubert syndrome; Gastrin signaling pathway; Head and neck squamous cell carcinoma; Thyroid hormones production and peripheral downstream signaling effects; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; Regucalcin in proximal tubule epithelial kidney cells; CAMKK2 pathway; Neuroinflammation; Autophagy; p53 transcriptional gene network; Pleural mesothelioma; Orexin receptor pathway; CCL18 signaling pathway; Network map of SARS-CoV-2 signaling pathway; Sphingolipid metabolism in senescence; Alzheimer's disease; Th17 cell differentiation pathway; GDNF signaling; DYRK1A involvement regarding cell proliferation in brain development; Modulation of PI3K-Akt-mTOR signaling by bioactive sphingolipids; Clock-controlled autophagy in bone metabolism; Primary ovarian insufficiency; A network map of Macrophage-stimulating protein (MSP) signaling; JAK-STAT signaling in the regulation of Beta-cells; Interferon type I signaling pathways; ErbB signaling pathway"	"85"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15047"	"Histone-lysine N-methyltransferase SETD1A OS=Homo sapiens OX=9606 GN=SETD1A PE=1 SV=3"	"1"	"1"	"1"	"1"	"1707"	"185.9"	"5.14"	""	"2.07"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00856, Pf11764"	"9739"	"ENSG00000099381"	"SETD1A"	"A6NP62; hsa:9739; O15047; Q6PIF3; Q8TAJ6"	"Formation of WDR5-containing histone-modifying complexes; PKMTs methylate histone lysines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"	"Histone modifications"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"P09455"	"Retinol-binding protein 1 OS=Homo sapiens OX=9606 GN=RBP1 PE=1 SV=2"	"7"	"1"	"1"	"1"	"135"	"15.8"	"5.11"	""	"2.07"	""	"1"	"other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00061"	"5947"	"ENSG00000114115"	"RBP1"	"A8K2Q0; B7Z7A0; E7EWV0; F2Z2F2; hsa:5947; P09455; Q6FGX8"	"Retinoid metabolism and transport; The canonical retinoid cycle in rods (twilight vision); Retinoid cycle disease events"	"Retinoblastoma gene in cancer; Vitamin A and carotenoid metabolism"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q7Z6M2"	"F-box only protein 33 OS=Homo sapiens OX=9606 GN=FBXO33 PE=1 SV=1"	"3"	"1"	"1"	"1"	"555"	"62.6"	"7.36"	""	"2.07"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other cell component"	""	"Pf12937"	"254170"	"ENSG00000165355"	"FBXO33"	"hsa:254170; Q6PIR2; Q7Z6M2; Q86TR2; Q86YE0"	""	""	"0"	"0"	"551.9"	"111.3"	"377.8"	"350.6"	"75.4"	"55.3"	"146.8"	"17.7"	"27.7"	"21.5"	"16.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15254"	"Peroxisomal acyl-coenzyme A oxidase 3 OS=Homo sapiens OX=9606 GN=ACOX3 PE=1 SV=2"	"2"	"1"	"1"	"1"	"700"	"77.6"	"7.25"	""	"2.06"	""	"1"	"other metabolic processes;other biological processes"	"cytosol;other cytoplasmic organelle"	"other molecular function"	"Pf01756, Pf02770"	"8310"	"ENSG00000087008"	"ACOX3"	"hsa:8310; O15254; Q96AJ8"	"Peroxisomal protein import; Beta-oxidation of pristanoyl-CoA"	"PPAR signaling pathway; Eicosanoid metabolism via cyclooxygenases (COX); Eicosanoid metabolism via lipooxygenases (LOX); Omega-3 / omega-6 fatty acid synthesis"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2I7"	"1-phosphatidylinositol 3-phosphate 5-kinase OS=Homo sapiens OX=9606 GN=PIKFYVE PE=1 SV=3"	"1"	"1"	"1"	"1"	"2098"	"237.0"	"6.70"	""	"2.06"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf00118, Pf00610, Pf01363, Pf01504"	"200576"	"ENSG00000115020"	"PIKFYVE"	"hsa:200576; Q08AR7; Q08AR8; Q53ST3; Q53T36; Q8N5H0; Q8NB67; Q9Y2I7"	"Synthesis of PIPs at the Golgi membrane; Synthesis of PIPs at the early endosome membrane; Synthesis of PIPs at the late endosome membrane"	""	"3"	"0"	"94.7"	"62.3"	"391.3"	"107.9"	"77.2"	"64.2"	"317.8"	"28.7"	"38.3"	"33.6"	"31.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07602"	"Prosaposin OS=Homo sapiens OX=9606 GN=PSAP PE=1 SV=2"	"2"	"1"	"2"	"1"	"524"	"58.1"	"5.17"	"234.29"	"2.06"	"1"	"1"	"other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02199, Pf03489, Pf05184"	"5660"	"ENSG00000197746"	"PSAP"	"hsa:5660; P07292; P07602; P15793; P78538; P78541; P78546; P78547; P78558; Q53Y86; Q6IBQ6; Q92739; Q92740; Q92741; Q92742"	"Neutrophil degranulation; Glycosphingolipid metabolism; G alpha (i) signalling events; Platelet degranulation ; Peptide ligand-binding receptors"	"Degradation pathway of sphingolipids, including diseases"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q08188"	"Protein-glutamine gamma-glutamyltransferase E OS=Homo sapiens OX=9606 GN=TGM3 PE=1 SV=4"	"2"	"1"	"2"	"1"	"693"	"76.6"	"5.86"	"241.22"	"2.06"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00868, Pf00927, Pf01841"	"7053"	"ENSG00000125780"	"TGM3"	"A8K5N6; B2RCR6; D3DVX1; hsa:7053; O95933; Q08188; Q32ML9; Q32MM0"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9H2W6"	"39S ribosomal protein L46, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL46 PE=1 SV=1"	"6"	"2"	"3"	"2"	"279"	"31.7"	"7.05"	"633.72"	"2.06"	"2"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf11788"	"26589"	"ENSG00000259494"	"MRPL46"	"B2RD75; hsa:26589; Q9H2W6; Q9HBU8"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"239.1"	"261.5"	"699.3"	"297.6"	"273.6"	"247.9"	"617.1"	"127.6"	"202.9"	"174.4"	"175.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TF72"	"Protein Shroom3 OS=Homo sapiens OX=9606 GN=SHROOM3 PE=1 SV=2"	"0"	"1"	"2"	"1"	"1996"	"216.7"	"7.80"	"271.36"	"2.06"	"1"	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf00595, Pf08687, Pf08688"	"57619"	"ENSG00000138771"	"SHROOM3"	"hsa:57619; Q5QTQ3; Q6ZRW3; Q8TF72; Q96IR9; Q9P247"	""	""	"0"	"0"	"150.3"	"249.2"	"595.4"	"288.2"	"269.8"	"295.0"	"893.2"	"212.8"	"403.6"	"298.0"	"299.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q53RT3"	"Retroviral-like aspartic protease 1 OS=Homo sapiens OX=9606 GN=ASPRV1 PE=1 SV=1"	"4"	"1"	"1"	"1"	"343"	"37.0"	"5.44"	""	"2.05"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes"	"other molecular function"	"Pf13975"	"151516"	"ENSG00000244617"	"ASPRV1"	"hsa:151516; Q53RT3; Q8N5P2; Q96LT3; Q96N43"	""	""	"0"	"0"	"29.3"	"27.1"	"53.6"	"15.0"	"16.0"	"8.9"	"79.4"	"12.1"	"14.6"	"9.9"	"10.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P10720"	"Platelet factor 4 variant OS=Homo sapiens OX=9606 GN=PF4V1 PE=1 SV=1"	"11"	"1"	"1"	"1"	"104"	"11.5"	"9.10"	""	"2.05"	""	"1"	"stress response;signal transduction;other biological processes"	"non-structural extracellular"	"signal transduction activity or receptor binding;other molecular function"	"Pf00048"	"5197"	"ENSG00000109272"	"PF4V1"	"A1L4S0; hsa:5197; P10720"	"Cell surface interactions at the vascular wall; Common Pathway of Fibrin Clot Formation"	"Overview of proinflammatory and profibrotic mediators"	"3"	"0"	"105.5"	"89.6"	"415.4"	"123.9"	"91.7"	"71.2"	"343.5"	"17.2"	"57.6"	"43.4"	"38.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WUD4"	"Coiled-coil domain-containing protein 12 OS=Homo sapiens OX=9606 GN=CCDC12 PE=1 SV=1"	"5"	"1"	"2"	"1"	"166"	"19.2"	"7.34"	"255.50"	"2.05"	"1"	"1"	""	"nucleus"	""	"Pf08315"	"151903"	"ENSG00000160799"	"CCDC12"	"hsa:151903; Q8N8I4; Q8WUD4"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"32.4"	"23.2"	"76.4"	"31.8"	"29.1"	"23.5"	"101.6"	"19.7"	"36.6"	"28.3"	"23.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NFJ9"	"Bardet-Biedl syndrome 1 protein OS=Homo sapiens OX=9606 GN=BBS1 PE=1 SV=1"	"2"	"1"	"2"	"1"	"593"	"65.0"	"7.93"	"269.78"	"2.05"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf14779"	"582"	"ENSG00000174483"	"BBS1"	"hsa:582; Q32MM9; Q32MN0; Q8NFJ9; Q96SN4"	"BBSome-mediated cargo-targeting to cilium"	"Ciliary landscape; Genes related to primary cilium development (based on CRISPR); Joubert syndrome; Ciliopathies; Bardet-Biedl syndrome"	"6"	"0"	"35.1"	"14.3"	"23.3"	"9.6"	"6.1"	"3.9"	"16.1"	"6.9"	"15.9"	"21.3"	"25.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9C0D4"	"Zinc finger protein 518B OS=Homo sapiens OX=9606 GN=ZNF518B PE=1 SV=2"	"1"	"1"	"1"	"1"	"1074"	"119.5"	"9.45"	""	"2.05"	""	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	""	"85460"	"ENSG00000178163"	"ZNF518B"	"hsa:85460; Q96LN8; Q9C0D4"	""	""	"0"	"0"	"5.7"	"11.3"	"32.9"	"6.7"	"7.1"	"6.8"	"25.0"	"7.9"	"11.5"	"8.8"	"11.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NWH9"	"SAFB-like transcription modulator OS=Homo sapiens OX=9606 GN=SLTM PE=1 SV=2"	"1"	"1"	"2"	"1"	"1034"	"117.1"	"7.87"	"261.42"	"2.05"	"1"	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf02037"	"79811"	"ENSG00000137776"	"SLTM"	"A8K5V8; B2RTX3; hsa:79811; Q2VPK7; Q52MB3; Q658J7; Q6ZNF2; Q86TK6; Q9H7C3; Q9H8U9; Q9NWH9"	""	""	"0"	"0"	"23.8"	"20.4"	"63.4"	"19.4"	"16.8"	"8.3"	"106.9"	"27.3"	"36.2"	"28.3"	"22.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BYI3"	"Hyccin OS=Homo sapiens OX=9606 GN=FAM126A PE=1 SV=2"	"2"	"1"	"1"	"1"	"521"	"57.6"	"8.16"	""	"2.04"	""	"1"	"other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf09790"	"84668"	"ENSG00000122591"	"HYCC1"	"A0A024RA06; A4D145; B8ZZJ1; hsa:84668; Q6N010; Q75MR4; Q7LDZ4; Q96MX1; Q96NQ6; Q9BYI3"	""	""	"0"	"0"	"11.9"	"7.9"	"31.1"	"11.0"	"6.8"	"6.6"	"29.0"	"4.6"	"16.1"	"24.0"	"21.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96PV7"	"Protein FAM193B OS=Homo sapiens OX=9606 GN=FAM193B PE=1 SV=3"	"1"	"1"	"1"	"1"	"902"	"96.5"	"7.90"	""	"2.04"	""	"1"	""	"nucleus;other cell component"	""	"Pf15914"	"54540"	"ENSG00000146067"	"FAM193B"	"E9PET5; Q96PV7; Q9NW00"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H3T3"	"Semaphorin-6B OS=Homo sapiens OX=9606 GN=SEMA6B PE=1 SV=4"	"3"	"1"	"1"	"1"	"888"	"95.2"	"8.48"	""	"2.04"	""	"1"	"cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes"	"signal transduction activity or receptor binding"	"Pf01403, Pf01437"	"10501"	"ENSG00000167680"	"SEMA6B"	"A5PKU4; F6IB19; hsa:10501; Q9H3T3; Q9NRK9"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60313"	"Dynamin-like 120 kDa protein, mitochondrial OS=Homo sapiens OX=9606 GN=OPA1 PE=1 SV=3"	"1"	"1"	"1"	"1"	"960"	"111.6"	"7.87"	""	"2.04"	""	"1"	"cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00350, Pf19434"	"4976"	"ENSG00000198836"	"OPA1"	"D3DNW4; E5KLJ5; E5KLJ6; E5KLJ7; E5KLK1; E5KLK2; hsa:4976; O60313"	"Regulation of Apoptosis"	"Orexin receptor pathway"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9ULH0"	"Kinase D-interacting substrate of 220 kDa OS=Homo sapiens OX=9606 GN=KIDINS220 PE=1 SV=3"	"1"	"1"	"2"	"1"	"1771"	"196.4"	"6.62"	"240.69"	"2.04"	"1"	"1"	"cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf07693, Pf12796"	"57498"	"ENSG00000134313"	"KIDINS220"	"A1L4N4; hsa:57498; Q4VC08; Q6MZU2; Q9H889; Q9H9E4; Q9NT37; Q9UF42; Q9ULH0"	"RND2 GTPase cycle; RND1 GTPase cycle; ARMS-mediated activation"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; Neural crest cell migration in cancer"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q8IUR0"	"Trafficking protein particle complex subunit 5 OS=Homo sapiens OX=9606 GN=TRAPPC5 PE=1 SV=1"	"7"	"1"	"1"	"1"	"188"	"20.8"	"9.66"	""	"2.03"	""	"1"	"cell organization and biogenesis;transport"	"cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf04051"	"126003"	"ENSG00000181029"	"TRAPPC5"	"A8K7I6; hsa:126003; Q8IUR0"	"RAB GEFs exchange GTP for GDP on RABs; COPII-mediated vesicle transport"	""	"2"	"0"	"74.8"	"87.7"	"452.7"	"234.8"	"171.8"	"146.6"	"359.1"	"32.9"	"118.0"	"106.8"	"102.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P58418"	"Clarin-1 OS=Homo sapiens OX=9606 GN=CLRN1 PE=1 SV=2"	"6"	"1"	"1"	"1"	"232"	"25.7"	"8.51"	""	"2.03"	""	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;other cell component"	""	""	"7401"	"ENSG00000163646"	"CLRN1"	"D3DNJ3; E1ACU9; hsa:7401; P58418; Q8N6A9"	""	""	"0"	"0"	"27.2"	"21.8"	"111.4"	"32.0"	"15.8"	"19.3"	"82.6"	"5.8"	"11.8"	"11.0"	"10.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92696"	"Geranylgeranyl transferase type-2 subunit alpha OS=Homo sapiens OX=9606 GN=RABGGTA PE=1 SV=2"	"2"	"1"	"1"	"1"	"567"	"65.0"	"5.67"	""	"2.03"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf01239, Pf07711"	"5875"	"ENSG00000100949; ENSG00000285193"	"RABGGTA"	"A8K5N2; D3DS69; hsa:5875; Q92696"	"RAB geranylgeranylation; TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9BY89"	"Uncharacterized protein KIAA1671 OS=Homo sapiens OX=9606 GN=KIAA1671 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1806"	"196.6"	"8.47"	"246.09"	"2.03"	"1"	"1"	""	""	""	"Pf15327"	"85379"	"ENSG00000197077"	"KIAA1671"	"B0QYF2; B7ZW08; hsa:85379; Q5THZ5; Q9BY89"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"O43379"	"WD repeat-containing protein 62 OS=Homo sapiens OX=9606 GN=WDR62 PE=1 SV=4"	"1"	"1"	"1"	"1"	"1518"	"165.8"	"5.91"	""	"2.03"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus"	""	"Pf00400"	"284403"	"ENSG00000075702"	"WDR62"	"hsa:284403; O43379; Q63HP9; Q659D7; Q8NBF7; Q96AD9"	""	"Primary ovarian insufficiency"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"n/a"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9H814"	"Phosphorylated adapter RNA export protein OS=Homo sapiens OX=9606 GN=PHAX PE=1 SV=1"	"3"	"1"	"2"	"1"	"394"	"44.4"	"5.40"	"240.81"	"2.03"	"1"	"1"	"transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf10258"	"51808"	"ENSG00000164902"	"PHAX"	"hsa:51808; Q9H814; Q9H8W1"	"RNA polymerase II transcribes snRNA genes; snRNP Assembly"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P2R3"	"Rabankyrin-5 OS=Homo sapiens OX=9606 GN=ANKFY1 PE=1 SV=2"	"1"	"1"	"1"	"1"	"1169"	"128.3"	"6.10"	""	"2.03"	""	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00023, Pf00651, Pf01363, Pf12796, Pf13637, Pf13857"	"51479"	"ENSG00000185722"	"ANKFY1"	"A8KA65; hsa:51479; Q5RKV4; Q9P2R3; Q9ULG5"	"RHOD GTPase cycle"	""	"1"	"0"	"9.8"	"10.4"	"27.1"	"6.4"	"9.5"	"4.9"	"27.1"	"2.4"	"7.4"	"5.0"	"2.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13308"	"Inactive tyrosine-protein kinase 7 OS=Homo sapiens OX=9606 GN=PTK7 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1070"	"118.3"	"7.09"	"327.41"	"2.02"	"1"	"1"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"kinase activity;other molecular function"	"Pf07679, Pf07714, Pf13927"	"5754"	"ENSG00000112655"	"PTK7"	"A8K974; B7Z477; E9PFZ5; hsa:5754; Q13308; Q13417; Q5T650; Q6IQ54; Q8NFA5; Q8NFA6; Q8NFA7; Q8NFA8"	""	""	"0"	"0"	"9.6"	"9.1"	"39.3"	"9.2"	"6.1"	"5.0"	"59.7"	"2.7"	"7.6"	"3.3"	"3.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P2W9"	"Syntaxin-18 OS=Homo sapiens OX=9606 GN=STX18 PE=1 SV=1"	"4"	"1"	"3"	"1"	"335"	"38.7"	"5.49"	"527.05"	"2.02"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf10496"	"53407"	"ENSG00000168818"	"STX18"	"hsa:53407; Q596L3; Q5TZP5; Q9P2W9"	"COPI-dependent Golgi-to-ER retrograde traffic"	""	"1"	"0"	"13.0"	"13.4"	"49.7"	"12.0"	"22.4"	"14.7"	"46.6"	"7.0"	"9.0"	"14.3"	"9.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NZM1"	"Myoferlin OS=Homo sapiens OX=9606 GN=MYOF PE=1 SV=1"	"1"	"1"	"1"	"1"	"2061"	"234.6"	"6.18"	""	"2.02"	""	"1"	"cell organization and biogenesis;stress response;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00168, Pf08150, Pf08151, Pf08165, Pf16165"	"26509"	"ENSG00000138119"	"MYOF"	"B3KQN5; hsa:26509; Q5VWW2; Q5VWW3; Q5VWW4; Q5VWW5; Q7Z642; Q8IWH0; Q9HBU3; Q9NZM0; Q9NZM1; Q9ULL3; Q9Y4U4"	""	"Aryl hydrocarbon receptor pathway; Nuclear receptors meta-pathway; Hepatitis C and hepatocellular carcinoma"	"3"	"0"	"250.4"	"203.5"	"894.6"	"197.9"	"112.3"	"95.0"	"409.3"	"90.9"	"219.2"	"466.8"	"1039.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NXD2"	"Myotubularin-related protein 10 OS=Homo sapiens OX=9606 GN=MTMR10 PE=1 SV=3"	"1"	"1"	"1"	"1"	"777"	"88.2"	"8.53"	""	"2.02"	""	"1"	""	"cytosol;other cell component"	""	"Pf06602, Pf12578"	"54893"	"ENSG00000166912; ENSG00000277086"	"MTMR10"	"hsa:54893; Q6P4Q6; Q9NXD2"	"Synthesis of PIPs at the early endosome membrane"	"15q13.3 copy number variation syndrome"	"2"	"0"	"46.2"	"71.4"	"98.3"	"29.0"	"35.5"	"26.5"	"96.9"	"41.0"	"30.3"	"34.0"	"41.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BZJ0"	"Crooked neck-like protein 1 OS=Homo sapiens OX=9606 GN=CRNKL1 PE=1 SV=4"	"2"	"1"	"2"	"1"	"848"	"100.4"	"8.00"	"237.94"	"2.02"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf02184"	"51340"	"ENSG00000101343"	"CRNKL1"	"A8K9T4; hsa:51340; Q5JY64; Q8WYI5; Q9BZI9; Q9BZJ0; Q9BZJ1; Q9BZJ2; Q9GZW7; Q9H8F8; Q9NQH5; Q9NYD8"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"17.1"	"15.8"	"60.1"	"8.0"	"12.1"	"10.2"	"49.2"	"7.7"	"12.9"	"8.9"	"7.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99633"	"Pre-mRNA-splicing factor 18 OS=Homo sapiens OX=9606 GN=PRPF18 PE=1 SV=1"	"3"	"1"	"1"	"1"	"342"	"39.8"	"8.15"	""	"2.01"	""	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf02840, Pf08799"	"8559"	"ENSG00000165630"	"PRPF18"	"hsa:8559; Q5T9P9; Q99633; Q9BUI9"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"0"	"15.1"	"17.3"	"62.1"	"17.1"	"13.4"	"13.1"	"50.2"	"5.7"	"15.4"	"12.6"	"27.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IXJ6"	"NAD-dependent protein deacetylase sirtuin-2 OS=Homo sapiens OX=9606 GN=SIRT2 PE=1 SV=2"	"3"	"1"	"2"	"1"	"389"	"43.2"	"5.36"	"236.51"	"2.01"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf02146"	"22933"	"ENSG00000068903; ENSG00000283100"	"SIRT2"	"A8K3V1; B2RB45; hsa:22933; O95889; Q8IXJ6; Q924Y7; Q9P0G8; Q9UNT0; Q9Y6E9; U5TP13"	"Initiation of Nuclear Envelope (NE) Reformation"	"NAD+ metabolism; NAD+ biosynthetic pathways; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence"	"4"	"0"	"4.4"	"8.7"	"29.1"	"11.1"	"9.0"	"6.3"	"26.7"	"1.6"	"4.7"	"5.5"	"7.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BZL4"	"Protein phosphatase 1 regulatory subunit 12C OS=Homo sapiens OX=9606 GN=PPP1R12C PE=1 SV=1"	"2"	"1"	"1"	"1"	"782"	"84.8"	"5.57"	""	"2.01"	""	"1"	"signal transduction"	"cytoskeleton;other cell component"	"enzyme regulator activity;other molecular function"	"Pf12796, Pf15898"	"54776"	"ENSG00000125503"	"PPP1R12C"	"B4DME2; hsa:54776; Q59FK8; Q6ZPD1; Q7L8F7; Q96HW1; Q9BZL4; Q9H5H5; Q9NT00"	""	"Focal adhesion"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9C037"	"E3 ubiquitin-protein ligase TRIM4 OS=Homo sapiens OX=9606 GN=TRIM4 PE=1 SV=2"	"2"	"1"	"4"	"1"	"500"	"57.4"	"8.10"	""	"2.01"	""	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00622, Pf00643, Pf15227"	"89122"	"ENSG00000146833"	"TRIM4"	"A4D298; hsa:89122; Q75MK1; Q96F06; Q9C036; Q9C037"	"SARS-CoV-2 activates/modulates innate and adaptive immune responses; Antigen processing: Ubiquitination & Proteasome degradation; Negative regulators of DDX58/IFIH1 signaling; TRAF6 mediated NF-kB activation; NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10; Ovarian tumor domain proteases; TRAF3-dependent IRF activation pathway; TRAF6 mediated IRF7 activation"	""	"9"	"0"	"229.2"	"228.2"	"743.8"	"158.6"	"122.0"	"89.2"	"609.2"	"65.0"	"97.0"	"77.0"	"107.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96T51"	"RUN and FYVE domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RUFY1 PE=1 SV=2"	"2"	"1"	"1"	"1"	"708"	"79.8"	"5.74"	""	"2.01"	""	"1"	"transport;signal transduction;other biological processes"	"other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01363, Pf02759"	"80230"	"ENSG00000176783; ENSG00000284260"	"RUFY1"	"hsa:80230; Q59FF3; Q71S93; Q96T51; Q9H6I3"	"Synthesis of PIPs at the plasma membrane"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"P46100"	"Transcriptional regulator ATRX OS=Homo sapiens OX=9606 GN=ATRX PE=1 SV=5"	"1"	"3"	"4"	"2"	"2492"	"282.4"	"6.58"	"818.19"	"2.01"	"3"	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"23.3"	"25.4"	"95.2"	"28.6"	"24.0"	"17.2"	"84.5"	"13.5"	"14.8"	"11.7"	"11.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6NXE6"	"Armadillo repeat-containing protein 6 OS=Homo sapiens OX=9606 GN=ARMC6 PE=1 SV=2"	"2"	"1"	"2"	"1"	"501"	"54.1"	"6.24"	"254.59"	"2.00"	"1"	"1"	"other biological processes"	"cytosol"	""	"Pf00514"	"93436"	"ENSG00000105676"	"ARMC6"	"B4DI98; hsa:93436; O94999; Q6NXE6; Q9BTH5"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q8ND56"	"Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3"	"4"	"2"	"3"	"1"	"463"	"50.5"	"9.52"	"627.52"	"0.00"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;signal transduction;other biological processes"	"cytosol;cytoskeleton;other cell component"	"nucleic acid binding activity"	"Pf09532, Pf12701"	"26065"	"ENSG00000257103; ENSG00000262860"	"LSM14A"	"B4DTG6; hsa:26065; Q76LX7; Q8ND56; Q96AR3; Q96K73; Q96SN5; Q9UFR3"	""	""	"0"	"0"	"45.9"	"43.6"	"110.4"	"50.6"	"46.7"	"48.7"	"113.8"	"22.0"	"53.3"	"35.8"	"33.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96KP1"	"Exocyst complex component 2 OS=Homo sapiens OX=9606 GN=EXOC2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"924"	"104.0"	"6.90"	"426.88"	"0.00"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf01833, Pf15469"	"55770"	"ENSG00000112685"	"EXOC2"	"B2RBE6; hsa:55770; Q5JPC8; Q96AN6; Q96KP1; Q9NUZ8; Q9UJM7"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"RalA downstream regulated genes; Chromosomal and microsatellite instability in colorectal cancer ; Ras signaling; Ciliary landscape"	"7"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IY26"	"Phospholipid phosphatase 6 OS=Homo sapiens OX=9606 GN=PLPP6 PE=1 SV=3"	"4"	"1"	"2"	"1"	"295"	"32.2"	"9.99"	"259.81"	"0.00"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus"	"other molecular function"	"Pf01569"	"403313"	"ENSG00000205808"	"PLPP6"	"B3KY05; hsa:403313; Q5JVJ6; Q8IY26; Q8NCK9"	"Cholesterol biosynthesis"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"O43290"	"U4/U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1"	"1"	"1"	"3"	"1"	"800"	"90.2"	"6.13"	"255.14"	"0.00"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	""	"Pf03343, Pf19252"	"9092"	"ENSG00000175467"	"SART1"	"A6NDN1; hsa:9092; O43290; Q53GB5"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"2.9"	"6.6"	"18.3"	"4.0"	"5.7"	"4.7"	"28.3"	"6.5"	"13.7"	"12.2"	"16.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96F86"	"Enhancer of mRNA-decapping protein 3 OS=Homo sapiens OX=9606 GN=EDC3 PE=1 SV=1"	"4"	"1"	"2"	"1"	"508"	"56.0"	"7.11"	"246.53"	"0.00"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03853, Pf09532, Pf12701, Pf16598"	"80153"	"ENSG00000179151"	"EDC3"	"B3KPH0; D3DW61; hsa:80153; Q96F86; Q9H797"	"mRNA decay by 5' to 3' exoribonuclease"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9P206"	"Uncharacterized protein KIAA1522 OS=Homo sapiens OX=9606 GN=KIAA1522 PE=1 SV=2"	"2"	"1"	"2"	"1"	"1035"	"107.0"	"9.73"	"245.71"	"0.00"	"1"	"1"	"other biological processes"	""	""	""	"57648"	"ENSG00000162522"	"KIAA1522"	"B4DQU8; B5MDY0; C9JH84; hsa:57648; Q8TCQ0; Q9P206"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"P11274"	"Breakpoint cluster region protein OS=Homo sapiens OX=9606 GN=BCR PE=1 SV=2"	"1"	"1"	"2"	"1"	"1271"	"142.7"	"7.03"	"244.82"	"0.00"	"1"	"1"	"cell adhesion;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00168, Pf00620, Pf00621, Pf09036, Pf19057"	"613"	"ENSG00000186716"	"BCR"	"hsa:613; P11274; P78501; Q12842; Q4LE80; Q6NZI3"	"RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOB GTPase cycle; Signaling by cytosolic FGFR1 fusion mutants; Signaling by FGFR1 in disease"	"Imatinib and chronic myeloid leukemia; Extrafollicular and follicular B cell activation by SARS-CoV-2"	"11"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N766"	"ER membrane protein complex subunit 1 OS=Homo sapiens OX=9606 GN=EMC1 PE=1 SV=1"	"2"	"1"	"2"	"1"	"993"	"111.7"	"7.66"	"244.44"	"0.00"	"1"	"1"	"cell organization and biogenesis"	"other membranes;ER/Golgi;other cell component"	""	"Pf07774, Pf13360"	"23065"	"ENSG00000127463"	"EMC1"	"A8K6F3; hsa:23065; Q14700; Q5TG62; Q63HL0; Q63HL3; Q8N766; Q8NBH8"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9GZZ8"	"Extracellular glycoprotein lacritin OS=Homo sapiens OX=9606 GN=LACRT PE=1 SV=1"	"8"	"1"	"2"	"1"	"138"	"14.2"	"5.50"	"241.80"	"0.00"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"non-structural extracellular;other cell component"	"signal transduction activity or receptor binding;other molecular function"	""	"90070"	"ENSG00000135413"	"LACRT"	"hsa:90070; Q9GZZ8"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9GZM5"	"Protein YIPF3 OS=Homo sapiens OX=9606 GN=YIPF3 PE=1 SV=1"	"3"	"1"	"2"	"1"	"350"	"38.2"	"5.76"	"233.21"	"0.00"	"1"	"1"	"other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	""	""	"25844"	"ENSG00000137207"	"YIPF3"	"hsa:25844; Q5JTD2; Q6FI85; Q8NI57; Q9GZM5; Q9NWE3; Q9Y3U9"	""	"11p11.2 copy number variation syndrome"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HCE0"	"Ectopic P granules protein 5 homolog OS=Homo sapiens OX=9606 GN=EPG5 PE=1 SV=2"	"1"	"1"	"1"	"1"	"2579"	"292.3"	"6.43"	""	"0.00"	""	"1"	"cell organization and biogenesis;other metabolic processes;transport;signal transduction;other biological processes"	"other cytoplasmic organelle;other cell component"	""	""	"57724"	"ENSG00000152223"	"EPG5"	"A2BDF3; hsa:57724; Q9H8C8; Q9HCE0"	""	""	"0"	"0"	"16.3"	"23.6"	"69.1"	"22.1"	"22.5"	"20.0"	"77.1"	"9.5"	"21.1"	"14.6"	"14.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P48200"	"Iron-responsive element-binding protein 2 OS=Homo sapiens OX=9606 GN=IREB2 PE=1 SV=4"	"1"	"1"	"1"	"1"	"963"	"105.0"	"7.05"	""	"0.00"	""	"1"	"other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;mitochondrion;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00330, Pf00694"	"3658"	"ENSG00000136381"	"IREB2"	"A0A0A6YY96; A8KAC7; E1CJT9; H0YKU0; hsa:3658; P48200; Q13095; Q1HE21; Q59FQ7; Q8WVK6; Q9UF17"	"Iron uptake and transport"	"Iron metabolism in placenta; Ferroptosis"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q8NG66"	"Serine/threonine-protein kinase Nek11 OS=Homo sapiens OX=9606 GN=NEK11 PE=1 SV=2"	"1"	"1"	"1"	"1"	"645"	"74.1"	"5.06"	""	"0.00"	""	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus"	"kinase activity;other molecular function"	"Pf00069"	"79858"	"ENSG00000114670"	"NEK11"	"A6NHD7; hsa:79858; Q5JPC0; Q8NG65; Q8NG66; Q8TBY1; Q9H5F4"	""	""	"0"	"0"	"196.4"	"209.6"	"409.8"	"178.1"	"181.5"	"177.3"	"606.8"	"138.2"	"246.4"	"202.0"	"163.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A0MZ66"	"Shootin-1 OS=Homo sapiens OX=9606 GN=SHTN1 PE=1 SV=4"	"2"	"1"	"1"	"1"	"631"	"71.6"	"5.33"	""	"0.00"	""	"1"	"cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	""	"57698"	"ENSG00000187164"	"SHTN1"	"A0MZ66; A8MYU7; B3KRD3; B3KRH2; B3KTE0; B3KTJ7; B3KTJ8; B4E3U1; B7Z7Z9; hsa:57698; Q68DG1; Q6PIM5; Q9HCH4; Q9NUV0"	"Recycling pathway of L1"	""	"1"	"0"	"170.8"	"125.3"	"1009.4"	"267.9"	"167.5"	"127.5"	"688.5"	"28.8"	"79.1"	"48.8"	"43.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IY82"	"Dynein regulatory complex subunit 7 OS=Homo sapiens OX=9606 GN=DRC7 PE=1 SV=3"	"2"	"1"	"1"	"1"	"874"	"103.4"	"5.67"	""	"0.00"	""	"1"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	""	""	"84229"	"ENSG00000159625"	"DRC7"	"A8K943; hsa:84229; Q8IY82; Q8NAA0; Q9H080"	""	""	"0"	"0"	"34.8"	"37.5"	"177.0"	"43.8"	"36.5"	"36.9"	"179.5"	"15.5"	"27.8"	"16.5"	"23.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04626"	"Receptor tyrosine-protein kinase erbB-2 OS=Homo sapiens OX=9606 GN=ERBB2 PE=1 SV=1"	"2"	"1"	"1"	"1"	"1255"	"137.8"	"5.91"	""	"0.00"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;kinase activity;other molecular function"	"Pf00757, Pf01030, Pf07714, Pf14843"	"2064"	"ENSG00000141736"	"ERBB2"	"B2RZG3; B4DHN3; hsa:2064; P04626; Q14256; Q6LDV1; Q9UMK4; X5D2V5"	"PIP3 activates AKT signaling; Constitutive Signaling by Aberrant PI3K in Cancer; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; RAF/MAP kinase cascade; SHC1 events in ERBB2 signaling; GRB7 events in ERBB2 signaling; Downregulation of ERBB2:ERBB3 signaling; GRB2 events in ERBB2 signaling; PI3K events in ERBB2 signaling; ERBB2 Regulates Cell Motility; ERBB2 Activates PTK6 Signaling; Signaling by ERBB2 KD Mutants; Signaling by ERBB2 TMD/JMD mutants; Sema4D induced cell migration and growth-cone collapse; PLCG1 events in ERBB2 signaling; TFAP2 (AP-2) family regulates transcription of growth factors and their receptors; Signaling by ERBB2 ECD mutants; Constitutive Signaling by Overexpressed ERBB2; Drug-mediated inhibition of ERBB2 signaling; Resistance of ERBB2 KD mutants to trastuzumab; Resistance of ERBB2 KD mutants to sapitinib; Resistance of ERBB2 KD mutants to tesevatinib; Resistance of ERBB2 KD mutants to neratinib; Resistance of ERBB2 KD mutants to osimertinib; Resistance of ERBB2 KD mutants to afatinib; Resistance of ERBB2 KD mutants to AEE788; Resistance of ERBB2 KD mutants to lapatinib; Drug resistance in ERBB2 TMD/JMD mutants"	"Leptin signaling pathway; Prolactin signaling pathway; Glioblastoma signaling pathways; Mammary gland development pathway - Puberty (Stage 2 of 4); Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4); Bladder cancer; Extracellular vesicle-mediated signaling in recipient cells; Focal adhesion; RAC1/PAK1/p38/MMP2 pathway; Pathways affected in adenoid cystic carcinoma; Physico-chemical features and toxicity-associated pathways; Endometrial cancer; Non-small cell lung cancer; Breast cancer pathway; Pancreatic adenocarcinoma pathway; EGF/EGFR signaling pathway; Head and neck squamous cell carcinoma; EGFR tyrosine kinase inhibitor resistance; 2q11.2 copy number variation syndrome; 17q12 copy number variation syndrome; ErbB signaling pathway; DNA damage response (only ATM dependent)"	"52"	"0"	"35.3"	"50.9"	"266.2"	"48.5"	"37.4"	"21.6"	"285.5"	"22.2"	"31.6"	"23.7"	"23.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IYI6"	"Exocyst complex component 8 OS=Homo sapiens OX=9606 GN=EXOC8 PE=1 SV=2"	"2"	"1"	"1"	"1"	"725"	"81.7"	"5.49"	""	"0.00"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf08700, Pf16528"	"149371"	"ENSG00000116903"	"EXOC8"	"B3KU33; hsa:149371; Q5TE82; Q8IYI6"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"RalA downstream regulated genes; Ciliary landscape"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q8IYT3"	"Coiled-coil domain-containing protein 170 OS=Homo sapiens OX=9606 GN=CCDC170 PE=1 SV=3"	"3"	"1"	"1"	"1"	"715"	"82.2"	"6.64"	""	"0.00"	""	"1"	"cell organization and biogenesis"	"cytoskeleton;ER/Golgi"	"cytoskeletal activity"	""	"80129"	"ENSG00000120262"	"CCDC170"	"hsa:80129; Q5VXB7; Q6P9E4; Q8IYT3; Q96KA9; Q9H5M3"	""	""	"0"	"0"	"22.8"	"24.0"	"216.6"	"42.5"	"46.5"	"35.3"	"265.7"	"20.1"	"22.8"	"17.5"	"13.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P1Z3"	"Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 OS=Homo sapiens OX=9606 GN=HCN3 PE=1 SV=2"	"2"	"1"	"1"	"1"	"774"	"86.0"	"9.72"	""	"0.00"	""	"1"	"transport;other biological processes"	"plasma membrane;other membranes;other cell component"	"transporter activity;other molecular function"	"Pf00027, Pf00520, Pf08412"	"57657"	"ENSG00000143630; ENSG00000263324"	"HCN3"	"D3DV90; hsa:57657; Q4VX12; Q8N6W6; Q9BWQ2; Q9P1Z3"	"HCN channels"	""	"1"	"0"	"59.8"	"81.9"	"342.7"	"79.5"	"78.8"	"56.8"	"602.8"	"82.6"	"126.0"	"74.7"	"74.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15418"	"Ribosomal protein S6 kinase alpha-1 OS=Homo sapiens OX=9606 GN=RPS6KA1 PE=1 SV=2"	"1"	"1"	"1"	"1"	"735"	"82.7"	"7.83"	""	"0.00"	""	"1"	"cell-cell signaling;cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069, Pf00433"	"6195"	"ENSG00000117676; ENSG00000281877"	"RPS6KA1"	"A6NGG4; A8K9K7; B2RDY8; B7Z5J0; E9PRI4; hsa:6195; Q15418; Q5SVM5; Q5SVM8; Q5SVM9; Q96C05; Q9BQK2"	"Senescence-Associated Secretory Phenotype (SASP); RSK activation; ERK/MAPK targets; Gastrin-CREB signalling pathway via PKC and MAPK; Recycling pathway of L1; CREB phosphorylation"	"IL-5 signaling pathway; Thyroid stimulating hormone (TSH) signaling pathway; Leptin signaling pathway; B cell receptor signaling pathway; Interleukin-11 signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Kit receptor signaling pathway; BDNF-TrkB signaling; Angiopoietin-like protein 8 regulatory pathway; TYROBP causal network in microglia; Thermogenesis; EGF/EGFR signaling pathway; Translation inhibitors in chronically activated PDGFRA cells; Cytoplasmic ribosomal proteins; Insulin signaling; Host-pathogen interaction of human coronaviruses - MAPK signaling; Pleural mesothelioma; Hippocampal synaptogenesis and neurogenesis; A network map of Macrophage-stimulating protein (MSP) signaling"	"26"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"P83105"	"Serine protease HTRA4 OS=Homo sapiens OX=9606 GN=HTRA4 PE=2 SV=1"	"3"	"1"	"1"	"1"	"476"	"50.9"	"8.02"	""	"0.00"	""	"1"	"protein metabolism;other biological processes"	"non-structural extracellular"	"other molecular function"	"Pf00219, Pf02163, Pf07648, Pf13180, Pf13365"	"203100"	"ENSG00000169495"	"HTRA4"	"hsa:203100; P83105; Q542Z4; Q6PF13"	""	""	"0"	"0"	"50.8"	"63.8"	"191.4"	"55.6"	"59.7"	"50.7"	"168.1"	"29.1"	"28.0"	"41.3"	"27.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82921"	"28S ribosomal protein S21, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS21 PE=1 SV=3"	"14"	"1"	"1"	"1"	"87"	"10.7"	"9.92"	""	"0.00"	""	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf01165"	"54460"	"ENSG00000266472"	"MRPS21"	"A0A075B746; hsa:54460; P82921; Q5TB11; Q9BST6"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"232.0"	"88.2"	"175.7"	"87.5"	"48.1"	"49.2"	"148.5"	"21.6"	"22.7"	"16.4"	"19.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96Q06"	"Perilipin-4 OS=Homo sapiens OX=9606 GN=PLIN4 PE=1 SV=2"	"1"	"1"	"1"	"1"	"1357"	"134.3"	"8.73"	""	"0.00"	""	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"39.1"	"43.5"	"91.6"	"54.5"	"49.5"	"56.0"	"89.1"	"31.8"	"53.3"	"32.4"	"24.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BVP2"	"Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2"	"7"	"3"	"3"	"3"	"549"	"62.0"	"9.16"	"1294.42"	""	"3"	""	"cell cycle OR cell proliferation;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01926, Pf08701"	"26354"	"ENSG00000163938"	"GNL3"	"B2RDC1; hsa:26354; Q5PU80; Q96SV6; Q96SV7; Q9BVP2; Q9UJY0"	"Major pathway of rRNA processing in the nucleolus and cytosol"	""	"1"	"0"	"101.4"	"112.4"	"363.1"	"95.2"	"128.6"	"77.2"	"346.5"	"46.5"	"103.5"	"98.2"	"110.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UEE9"	"Craniofacial development protein 1 OS=Homo sapiens OX=9606 GN=CFDP1 PE=1 SV=1"	"4"	"1"	"2"	"1"	"299"	"33.6"	"4.81"	"932.34"	""	"1"	""	"cell adhesion;cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	""	"Pf07572"	"10428"	"ENSG00000153774"	"CFDP1"	"hsa:10428; O00393; O00404; Q9UEE9; Q9UEF0; Q9UEF1; Q9UEF8"	""	""	"0"	"0"	"53.2"	"55.8"	"211.5"	"65.0"	"71.6"	"66.6"	"349.0"	"38.6"	"54.8"	"56.4"	"34.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13617"	"Cullin-2 OS=Homo sapiens OX=9606 GN=CUL2 PE=1 SV=2"	"4"	"3"	"3"	"3"	"745"	"86.9"	"6.92"	"904.69"	""	"3"	""	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;signal transduction"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00888, Pf10557"	"8453"	"ENSG00000108094"	"CUL2"	"B3KT95; B7Z6K8; D3DRY6; G3V1S2; hsa:8453; O00200; Q13617; Q5T2B6; Q9UNF9"	"Antigen processing: Ubiquitination & Proteasome degradation; Regulation of expression of SLITs and ROBOs; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Neddylation"	"Type 2 papillary renal cell carcinoma; Hijack of ubiquitination by SARS-CoV-2"	"6"	"0"	"45.6"	"55.5"	"185.5"	"55.6"	"49.1"	"41.5"	"211.0"	"19.4"	"39.9"	"26.2"	"26.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62273"	"40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2"	"34"	"3"	"3"	"3"	"56"	"6.7"	"10.13"	"830.94"	""	"3"	""	"protein metabolism;other metabolic processes"	"other membranes;cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00253"	"6235"	"ENSG00000213741"	"RPS29"	"A8MZ73; hsa:6235; P30054; P62273"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins; 11p11.2 copy number variation syndrome"	"20"	"0"	"212.0"	"234.4"	"678.6"	"202.8"	"234.6"	"289.8"	"848.7"	"112.7"	"158.8"	"160.9"	"122.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92615"	"La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3"	"2"	"1"	"2"	"1"	"738"	"80.5"	"6.92"	"774.46"	""	"1"	""	"other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity"	"Pf05383"	"23185"	"ENSG00000107929"	"LARP4B"	"A7MD20; hsa:23185; Q5T3R3; Q5T3R4; Q5T3R5; Q68CY4; Q92615"	""	""	"0"	"0"	"14.1"	"16.7"	"55.6"	"13.3"	"14.0"	"16.5"	"87.9"	"10.0"	"15.0"	"9.9"	"14.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z392"	"Trafficking protein particle complex subunit 11 OS=Homo sapiens OX=9606 GN=TRAPPC11 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1133"	"128.8"	"7.14"	"757.02"	""	"1"	""	"cell organization and biogenesis;transport;other biological processes"	"cytosol;ER/Golgi;other cell component"	""	"Pf11817, Pf12742"	"60684"	"ENSG00000168538"	"TRAPPC11"	"A4QPB8; B2RCD6; hsa:60684; Q5U5I7; Q6FI73; Q7Z392; Q86T25; Q9H0L1; Q9H5K9; Q9H8Q1; Q9H9I7"	"RAB GEFs exchange GTP for GDP on RABs"	"Genes related to primary cilium development (based on CRISPR)"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62072"	"Mitochondrial import inner membrane translocase subunit Tim10 OS=Homo sapiens OX=9606 GN=TIMM10 PE=1 SV=1"	"16"	"1"	"1"	"1"	"90"	"10.3"	"6.29"	"733.83"	""	"1"	""	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf02953"	"26519"	"ENSG00000134809"	"TIMM10"	"A8K136; hsa:26519; P62072; Q9WV99; Q9WVA0; Q9Y5J8"	"Mitochondrial protein import"	""	"1"	"0"	"38.8"	"46.4"	"194.0"	"67.7"	"53.6"	"47.4"	"251.1"	"24.8"	"50.4"	"47.6"	"44.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15078"	"Centrosomal protein of 290 kDa OS=Homo sapiens OX=9606 GN=CEP290 PE=1 SV=2"	"1"	"3"	"3"	"1"	"2479"	"290.2"	"5.95"	"732.42"	""	"3"	""	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf16574"	"80184"	"ENSG00000198707"	"CEP290"	"hsa:80184; O15078; Q1PSK5; Q66GS8; Q9H2G6; Q9H6Q7; Q9H8I0"	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Neutrophil degranulation"	"Clear cell renal cell carcinoma pathways; Ciliary landscape; Joubert syndrome; Ciliopathies; Bardet-Biedl syndrome"	"13"	"0"	"53.2"	"83.9"	"354.2"	"89.2"	"80.8"	"66.7"	"409.0"	"60.6"	"92.6"	"51.8"	"60.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25490"	"Transcriptional repressor protein YY1 OS=Homo sapiens OX=9606 GN=YY1 PE=1 SV=2"	"4"	"1"	"2"	"1"	"414"	"44.7"	"6.25"	"729.28"	""	"1"	""	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00096"	"7528"	"ENSG00000100811"	"YY1"	"hsa:7528; P25490; Q14935"	"UCH proteinases; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; DNA Damage Recognition in GG-NER; TFAP2 (AP-2) family regulates transcription of growth factors and their receptors"	"Sterol regulatory element-binding proteins (SREBP) signaling; Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4); Pleural mesothelioma"	"8"	"0"	"26.0"	"26.9"	"93.2"	"26.6"	"24.6"	"16.2"	"122.8"	"15.6"	"38.3"	"35.2"	"35.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IVW6"	"AT-rich interactive domain-containing protein 3B OS=Homo sapiens OX=9606 GN=ARID3B PE=1 SV=2"	"5"	"2"	"2"	"2"	"561"	"60.6"	"7.52"	"716.00"	""	"2"	""	"other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf01388"	"10620"	"ENSG00000179361"	"ARID3B"	"hsa:10620; O95443; Q59HC9; Q6P9C9; Q8IVW6"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61081"	"NEDD8-conjugating enzyme Ubc12 OS=Homo sapiens OX=9606 GN=UBE2M PE=1 SV=1"	"9"	"2"	"2"	"2"	"183"	"20.9"	"7.69"	"710.17"	""	"2"	""	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00179"	"9040"	"ENSG00000130725"	"UBE2M"	"hsa:9040; O76069; P61081; Q8VC50"	"Antigen processing: Ubiquitination & Proteasome degradation; Dectin-1 mediated noncanonical NF-kB signaling; NIK-->noncanonical NF-kB signaling; Neddylation; TGF-beta receptor signaling activates SMADs"	""	"5"	"0"	"137.7"	"143.5"	"605.4"	"131.4"	"77.8"	"60.9"	"782.8"	"55.2"	"67.7"	"56.8"	"44.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H0R4"	"Haloacid dehalogenase-like hydrolase domain-containing protein 2 OS=Homo sapiens OX=9606 GN=HDHD2 PE=1 SV=1"	"7"	"1"	"1"	"1"	"259"	"28.5"	"6.24"	"701.34"	""	"1"	""	"other metabolic processes"	""	"other molecular function"	"Pf13242, Pf13344"	"84064"	"ENSG00000167220"	"HDHD2"	"A8K7T3; hsa:84064; Q96NV4; Q9H0R4"	""	""	"0"	"0"	"7.7"	"8.7"	"46.1"	"6.9"	"4.3"	"4.5"	"40.9"	"2.5"	"2.7"	"4.8"	"0.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9NYJ1"	"Cytochrome c oxidase assembly factor 4 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=COA4 PE=1 SV=2"	"17"	"1"	"1"	"1"	"87"	"10.1"	"6.04"	"684.00"	""	"1"	""	"cell organization and biogenesis"	"mitochondrion"	""	""	"51287"	"ENSG00000181924"	"COA4"	"B2RAA0; hsa:51287; Q69YU4; Q9NYJ1"	"Mitochondrial protein import"	""	"1"	"0"	"47.7"	"77.2"	"257.9"	"101.8"	"94.0"	"96.4"	"213.1"	"39.1"	"95.3"	"55.0"	"49.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9ULX3"	"RNA-binding protein NOB1 OS=Homo sapiens OX=9606 GN=NOB1 PE=1 SV=1"	"4"	"1"	"2"	"1"	"412"	"46.6"	"7.18"	"673.11"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf08772, Pf15017, Pf17146"	"28987"	"ENSG00000141101"	"NOB1"	"hsa:28987; Q7L6B7; Q7M4M4; Q7Z4B5; Q9NWB0; Q9ULX3"	"Major pathway of rRNA processing in the nucleolus and cytosol"	""	"1"	"0"	"34.7"	"35.6"	"130.1"	"37.0"	"40.0"	"32.3"	"126.6"	"17.5"	"27.5"	"25.6"	"23.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P02768"	"Serum albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2"	"2"	"1"	"1"	"1"	"609"	"69.3"	"6.28"	"667.07"	""	"1"	""	"stress response;other biological processes"	"non-structural extracellular;ER/Golgi;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00273"	"213"	"ENSG00000163631"	"ALB"	"E7ESS9; hsa:213; O95574; P02768; P04277; Q13140; Q645G4; Q68DN5; Q6UXK4; Q86YG0; Q8IUK7; Q9P157; Q9P1I7; Q9UHS3; Q9UJZ0"	"Cytoprotection by HMOX1; Scavenging of heme from plasma; Platelet degranulation ; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Aspirin ADME; Ciprofloxacin ADME; Recycling of bile acids and salts; Prednisone ADME; Heme degradation; HDL remodeling; Heme biosynthesis"	"Selenium micronutrient network; Vitamin B12 metabolism; Folate metabolism; Complement system; VEGFA-VEGFR2 signaling"	"17"	"0"	"21.4"	"17.7"	"69.9"	"12.0"	"13.6"	"12.2"	"97.7"	"5.7"	"15.3"	"28.4"	"12.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86UE8"	"Serine/threonine-protein kinase tousled-like 2 OS=Homo sapiens OX=9606 GN=TLK2 PE=1 SV=2"	"1"	"1"	"2"	"1"	"772"	"87.6"	"8.41"	"631.64"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"11011"	"ENSG00000146872"	"TLK2"	"D3DU07; hsa:11011; Q86UE8; Q9UKI7; Q9Y4F7"	""	"miRNA regulation of DNA damage response; DNA damage response"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"O95071"	"E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2"	"1"	"2"	"2"	"2"	"2799"	"309.2"	"5.85"	"627.07"	""	"2"	""	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00632, Pf00658, Pf11547"	"51366"	"ENSG00000104517"	"UBR5"	"B2RP24; hsa:51366; J3KMW7; O94970; O95071; Q9NPL3"	""	"Mesodermal commitment pathway"	"1"	"0"	"88.3"	"109.5"	"290.3"	"92.9"	"92.1"	"73.1"	"279.4"	"39.1"	"49.8"	"44.3"	"40.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKV3"	"Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2"	"1"	"2"	"2"	"2"	"1341"	"151.8"	"6.43"	"617.07"	""	"2"	""	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02037, Pf16294"	"22985"	"ENSG00000100813"	"ACIN1"	"B2RTT4; D3DS45; hsa:22985; O75158; Q9UG91; Q9UKV1; Q9UKV2; Q9UKV3"	"mRNA Splicing - Major Pathway; Apoptotic cleavage of cellular proteins"	""	"2"	"0"	"49.9"	"51.0"	"213.6"	"31.5"	"41.8"	"22.6"	"279.4"	"28.7"	"35.9"	"27.2"	"23.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q969T9"	"WW domain-binding protein 2 OS=Homo sapiens OX=9606 GN=WBP2 PE=1 SV=1"	"6"	"2"	"2"	"2"	"261"	"28.1"	"5.91"	"610.14"	""	"2"	""	"cell organization and biogenesis;RNA metabolism OR transcription;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02893"	"23558"	"ENSG00000132471"	"WBP2"	"B4DFG2; hsa:23558; O95638; Q969T9"	""	""	"0"	"0"	"122.8"	"181.4"	"393.7"	"141.2"	"208.0"	"176.5"	"358.8"	"101.2"	"150.2"	"93.8"	"102.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A5YKK6"	"CCR4-NOT transcription complex subunit 1 OS=Homo sapiens OX=9606 GN=CNOT1 PE=1 SV=2"	"1"	"2"	"2"	"2"	"2376"	"266.8"	"7.11"	"583.16"	""	"2"	""	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf04054, Pf12842, Pf16415, Pf16417, Pf16418"	"23019"	"ENSG00000125107"	"CNOT1"	"A5YKK6; hsa:23019; Q68DX7; Q7Z3K2; Q8IWB8; Q8TB53; Q9BVZ6; Q9UFR8; Q9UI27; Q9Y2L0"	"Deadenylation of mRNA; TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"	"Ciliary landscape"	"3"	"0"	"42.5"	"63.1"	"190.3"	"51.2"	"56.7"	"37.7"	"165.9"	"25.6"	"46.5"	"48.4"	"48.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60934"	"Nibrin OS=Homo sapiens OX=9606 GN=NBN PE=1 SV=1"	"2"	"1"	"1"	"1"	"754"	"84.9"	"6.90"	"572.30"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00498, Pf08599, Pf16508"	"4683"	"ENSG00000104320"	"NBN"	"B2R626; B2RNC5; hsa:4683; O60672; O60934; Q32NF7; Q53FM6; Q63HR6; Q7LDM2"	"Resolution of D-loop Structures through Holliday Junction Intermediates; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; Meiotic recombination; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; DNA Damage/Telomere Stress Induced Senescence; Nonhomologous End-Joining (NHEJ); HDR through MMEJ (alt-NHEJ); Sensing of DNA Double Strand Breaks"	"miRNA regulation of DNA damage response; Homologous recombination; DDX1 as a regulatory component of the Drosha microprocessor; ATM signaling in development and disease ; Breast cancer pathway; DNA repair pathways, full network; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; Primary ovarian insufficiency; DNA damage response"	"29"	"0"	"11.6"	"6.3"	"29.3"	"7.8"	"7.4"	"5.9"	"61.5"	"8.0"	"48.5"	"115.9"	"233.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y376"	"Calcium-binding protein 39 OS=Homo sapiens OX=9606 GN=CAB39 PE=1 SV=1"	"8"	"2"	"2"	"2"	"341"	"39.8"	"6.89"	"571.07"	""	"2"	""	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"non-structural extracellular;other membranes;cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;other molecular function"	"Pf08569"	"51719"	"ENSG00000135932"	"CAB39"	"A8K8L7; hsa:51719; Q9Y376"	"Neutrophil degranulation; Energy dependent regulation of mTOR by LKB1-AMPK"	"AMP-activated protein kinase signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Endochondral ossification; Endochondral ossification with skeletal dysplasias"	"6"	"0"	"110.8"	"89.7"	"429.3"	"126.7"	"72.2"	"62.3"	"489.9"	"59.4"	"177.1"	"179.4"	"173.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UQ84"	"Exonuclease 1 OS=Homo sapiens OX=9606 GN=EXO1 PE=1 SV=2"	"3"	"2"	"2"	"2"	"846"	"94.0"	"8.31"	"566.69"	""	"2"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00752, Pf00867"	"9156"	"ENSG00000174371"	"EXO1"	"hsa:9156; O60545; O75214; O75466; Q5T396; Q96IJ1; Q9UG38; Q9UNW0; Q9UQ84"	"Resolution of D-loop Structures through Holliday Junction Intermediates; Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"DNA repair pathways, full network; DNA mismatch repair; Primary ovarian insufficiency"	"19"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92686"	"Neurogranin OS=Homo sapiens OX=9606 GN=NRGN PE=1 SV=1"	"19"	"1"	"1"	"1"	"78"	"7.6"	"7.87"	"541.66"	""	"1"	""	"developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00612"	"4900"	"ENSG00000154146"	"NRGN"	"hsa:4900; Q92686"	"Long-term potentiation"	""	"1"	"0"	"11.3"	"15.0"	"59.4"	"17.8"	"10.3"	"8.0"	"126.1"	"14.0"	"20.7"	"18.7"	"12.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9GZT8"	"NIF3-like protein 1 OS=Homo sapiens OX=9606 GN=NIF3L1 PE=1 SV=2"	"5"	"2"	"2"	"2"	"377"	"41.9"	"6.65"	"539.05"	""	"2"	""	"developmental processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01784"	"60491"	"ENSG00000196290"	"NIF3L1"	"hsa:60491; Q53TX4; Q6X735; Q9GZT8; Q9H2D2; Q9HC18"	""	""	"0"	"0"	"146.0"	"127.7"	"375.2"	"99.3"	"89.5"	"51.8"	"484.0"	"68.1"	"57.2"	"41.7"	"53.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q969Y2"	"tRNA modification GTPase GTPBP3, mitochondrial OS=Homo sapiens OX=9606 GN=GTPBP3 PE=1 SV=2"	"3"	"1"	"1"	"1"	"492"	"52.0"	"6.48"	"525.72"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01926, Pf10396, Pf12631"	"84705"	"ENSG00000130299"	"GTPBP3"	"A6NFH1; A6NIG5; A6NKR4; A8K7B4; B7Z4V8; hsa:84705; Q8TCY6; Q8WUW9; Q969G4; Q969Y2; Q9BX61"	"tRNA modification in the mitochondrion"	""	"1"	"0"	"10.8"	"7.2"	"48.6"	"7.6"	"6.3"	"6.5"	"67.5"	"6.8"	"6.0"	"4.2"	"5.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H6R0"	"ATP-dependent RNA helicase DHX33 OS=Homo sapiens OX=9606 GN=DHX33 PE=1 SV=2"	"2"	"1"	"1"	"1"	"707"	"78.8"	"8.91"	"520.97"	""	"1"	""	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"56919"	"ENSG00000005100"	"DHX33"	"B4DHF9; hsa:56919; Q4G149; Q5CZ73; Q9H5M9; Q9H6R0"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5UIP0"	"Telomere-associated protein RIF1 OS=Homo sapiens OX=9606 GN=RIF1 PE=1 SV=2"	"1"	"2"	"2"	"2"	"2472"	"274.3"	"5.52"	"513.12"	""	"2"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	""	"Pf12231"	"55183"	"ENSG00000080345"	"RIF1"	"A6NC27; C9JBR1; hsa:55183; Q5H9R3; Q5UIP0; Q5UIP2; Q66YK6; Q6PRU2; Q8TE94; Q99772; Q9H830; Q9H9B9; Q9NVP5; Q9Y4R4"	"Nonhomologous End-Joining (NHEJ)"	"ATM signaling in development and disease"	"2"	"0"	"74.8"	"71.6"	"256.0"	"59.1"	"44.8"	"46.1"	"239.3"	"27.9"	"35.3"	"34.8"	"32.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86UK0"	"ATP-binding cassette sub-family A member 12 OS=Homo sapiens OX=9606 GN=ABCA12 PE=1 SV=3"	"0"	"1"	"2"	"1"	"2595"	"293.0"	"7.75"	"512.33"	""	"1"	""	"cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;transporter activity;other molecular function"	"Pf00005, Pf12698"	"26154"	"ENSG00000144452"	"ABCA12"	"hsa:26154; Q53QE2; Q53S55; Q86UK0; Q8IZW6; Q96JT3; Q9Y4M5"	"ABC transporters in lipid homeostasis; Defective ABCA12 causes ARCI4B"	""	"2"	"0"	"175.5"	"245.9"	"1080.1"	"248.4"	"185.2"	"157.0"	"1440.6"	"163.0"	"246.2"	"174.5"	"181.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NZT2"	"Opioid growth factor receptor OS=Homo sapiens OX=9606 GN=OGFR PE=1 SV=3"	"3"	"1"	"1"	"1"	"677"	"73.3"	"4.84"	"506.23"	""	"1"	""	"other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf04664, Pf04680"	"11054"	"ENSG00000060491"	"OGFR"	"hsa:11054; O96029; Q4VXW5; Q96CM2; Q9BQW1; Q9H4H0; Q9H7J5; Q9NZT2; Q9NZT3; Q9NZT4"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q96BM9"	"ADP-ribosylation factor-like protein 8A OS=Homo sapiens OX=9606 GN=ARL8A PE=1 SV=1"	"12"	"2"	"2"	"1"	"186"	"21.4"	"7.77"	"505.90"	""	"2"	""	"cell cycle OR cell proliferation;transport;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00025"	"127829"	"ENSG00000143862"	"ARL8A"	"B3KXD0; hsa:127829; Q96BM9"	"Neutrophil degranulation"	""	"1"	"0"	"9.2"	"8.3"	"24.2"	"5.3"	"6.8"	"5.2"	"45.3"	"6.3"	"6.5"	"5.9"	"6.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P021"	"Cysteine-rich PDZ-binding protein OS=Homo sapiens OX=9606 GN=CRIPT PE=1 SV=1"	"12"	"1"	"1"	"1"	"101"	"11.2"	"9.47"	"504.31"	""	"1"	""	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf10235"	"9419"	"ENSG00000119878"	"CRIPT"	"hsa:9419; Q9P021"	""	""	"0"	"0"	"8.8"	"4.7"	"26.7"	"11.1"	"4.3"	"4.0"	"66.7"	"10.2"	"21.8"	"23.7"	"26.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6NXR4"	"TELO2-interacting protein 2 OS=Homo sapiens OX=9606 GN=TTI2 PE=1 SV=1"	"3"	"2"	"2"	"2"	"508"	"56.9"	"7.09"	"501.18"	""	"2"	""	"other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf10521"	"80185"	"ENSG00000129696"	"TTI2"	"D3DSV7; hsa:80185; Q6NXR4; Q96IM2; Q9H5N4"	""	""	"0"	"0"	"124.3"	"162.0"	"493.9"	"133.6"	"91.1"	"87.8"	"307.8"	"18.1"	"36.2"	"34.2"	"42.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A0A096LP55"	"Cytochrome b-c1 complex subunit 6-like, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRHL PE=3 SV=1"	"7"	"1"	"2"	"1"	"91"	"10.7"	"4.44"	"499.66"	""	"1"	""	"other metabolic processes;transport"	"other membranes;mitochondrion"	""	"Pf02320"	"440567"	"ENSG00000233954"	"UQCRHL"	"A0A096LP55; hsa:440567"	""	"Nonalcoholic fatty liver disease"	"1"	"0"	"458.7"	"619.3"	"1571.7"	"457.7"	"459.5"	"444.3"	"1681.6"	"246.1"	"371.3"	"262.5"	"281.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95400"	"CD2 antigen cytoplasmic tail-binding protein 2 OS=Homo sapiens OX=9606 GN=CD2BP2 PE=1 SV=1"	"4"	"1"	"1"	"1"	"341"	"37.6"	"4.61"	"495.36"	""	"1"	""	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf02213"	"10421"	"ENSG00000169217"	"CD2BP2"	"B2RDX2; hsa:10421; O95400; Q9ULP2"	""	"mRNA processing; Ciliary landscape"	"2"	"0"	"12.1"	"15.3"	"44.5"	"7.9"	"10.8"	"9.1"	"52.2"	"10.1"	"15.4"	"11.3"	"13.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q3V6T2"	"Girdin OS=Homo sapiens OX=9606 GN=CCDC88A PE=1 SV=2"	"1"	"2"	"2"	"1"	"1871"	"215.9"	"6.21"	"494.02"	""	"2"	""	"cell organization and biogenesis;DNA metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf19047"	"55704"	"ENSG00000115355"	"CCDC88A"	"A1IGE7; B7ZM78; C9JG83; hsa:55704; Q3V6T2; Q53SF1; Q581G3; Q5HYD0; Q7Z339; Q7Z3C5"	"RND3 GTPase cycle; RND1 GTPase cycle"	"Mesodermal commitment pathway"	"3"	"0"	"58.0"	"77.4"	"357.4"	"92.1"	"53.9"	"49.1"	"1326.1"	"115.5"	"108.4"	"97.4"	"80.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z5R6"	"Amyloid beta A4 precursor protein-binding family B member 1-interacting protein OS=Homo sapiens OX=9606 GN=APBB1IP PE=1 SV=1"	"1"	"1"	"2"	"1"	"666"	"73.1"	"5.59"	"485.14"	""	"1"	""	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	""	"Pf00169, Pf00788"	"54518"	"ENSG00000077420"	"APBB1IP"	"hsa:54518; Q7Z5R6; Q8IWS8; Q8IYL7; Q8IZZ7"	"Signaling by BRAF and RAF1 fusions; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; GRB2:SOS provides linkage to MAPK signaling for Integrins ; p130Cas linkage to MAPK signaling for integrins"	"TYROBP causal network in microglia"	"11"	"0"	"424.1"	"449.8"	"770.7"	"473.6"	"443.2"	"472.6"	"701.2"	"199.3"	"355.4"	"284.1"	"259.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q71RC2"	"La-related protein 4 OS=Homo sapiens OX=9606 GN=LARP4 PE=1 SV=3"	"2"	"1"	"1"	"1"	"724"	"80.5"	"6.61"	"469.77"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity"	"Pf05383"	"113251"	"ENSG00000161813"	"LARP4"	"A8K6T1; E9PDG5; G3XAA8; G5E976; hsa:113251; Q5CZ97; Q6ZV14; Q71RC2; Q96NF9"	""	""	"0"	"0"	"8.3"	"10.9"	"51.5"	"10.6"	"6.9"	"5.8"	"54.3"	"4.3"	"7.0"	"3.5"	"0.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"O43663"	"Protein regulator of cytokinesis 1 OS=Homo sapiens OX=9606 GN=PRC1 PE=1 SV=2"	"2"	"1"	"1"	"1"	"620"	"71.6"	"6.68"	"460.53"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03999"	"9055"	"ENSG00000198901"	"PRC1"	"A6NC44; B4DLR1; H9KV59; hsa:9055; O43663; Q9BSB6"	"RHO GTPases activate CIT"	""	"1"	"0"	"12.3"	"10.9"	"29.6"	"10.2"	"7.4"	"7.1"	"44.2"	"11.3"	"14.6"	"23.8"	"40.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HBM1"	"Kinetochore protein Spc25 OS=Homo sapiens OX=9606 GN=SPC25 PE=1 SV=1"	"6"	"1"	"1"	"1"	"224"	"26.1"	"8.00"	"455.26"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf08234"	"57405"	"ENSG00000152253; ENSG00000277909"	"SPC25"	"A8K4X8; D3DPC0; hsa:57405; Q9HBM1"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	""	"6"	"0"	"3.9"	"12.8"	"27.3"	"18.5"	"16.4"	"19.9"	"65.8"	"6.4"	"12.5"	"7.9"	"10.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y6X9"	"ATPase MORC2 OS=Homo sapiens OX=9606 GN=MORC2 PE=1 SV=2"	"1"	"1"	"1"	"1"	"1032"	"117.8"	"8.38"	"446.78"	""	"1"	""	"cell organization and biogenesis;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf07496, Pf13589, Pf17942"	"22880"	"ENSG00000133422"	"MORC2"	"B2RNB1; hsa:22880; Q9UF28; Q9Y6V2; Q9Y6X9"	"Fatty acyl-CoA biosynthesis"	""	"1"	"0"	"14.3"	"12.6"	"47.1"	"13.0"	"12.4"	"8.0"	"65.6"	"6.7"	"11.3"	"8.2"	"11.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14061"	"Cytochrome c oxidase copper chaperone OS=Homo sapiens OX=9606 GN=COX17 PE=1 SV=2"	"25"	"1"	"1"	"1"	"63"	"6.9"	"7.24"	"439.52"	""	"1"	""	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"mitochondrion;other cell component"	"enzyme regulator activity;other molecular function"	"Pf05051"	"10063"	"ENSG00000138495"	"COX17"	"B2R5D2; D3DN84; hsa:10063; Q14061; Q3MHD6"	"Mitochondrial protein import"	"Electron transport chain: OXPHOS system in mitochondria; Copper homeostasis; IL-18 signaling pathway; Mitochondrial complex IV assembly"	"5"	"0"	"42.1"	"41.5"	"158.7"	"50.2"	"57.1"	"39.3"	"187.2"	"18.2"	"34.6"	"23.5"	"19.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBB5"	"Methyl-CpG-binding domain protein 2 OS=Homo sapiens OX=9606 GN=MBD2 PE=1 SV=1"	"3"	"1"	"1"	"1"	"411"	"43.2"	"10.04"	"422.49"	""	"1"	""	"cell-cell signaling;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01429, Pf14048, Pf16564"	"8932"	"ENSG00000134046"	"MBD2"	"hsa:8932; O95242; Q9UBB5; Q9UIS8"	"NoRC negatively regulates rRNA expression; RNA Polymerase I Promoter Opening"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"3"	"0"	"7.2"	"6.3"	"27.6"	"6.7"	"9.8"	"4.6"	"46.6"	"4.1"	"7.6"	"5.9"	"7.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A6NDG6"	"Glycerol-3-phosphate phosphatase OS=Homo sapiens OX=9606 GN=PGP PE=1 SV=1"	"6"	"1"	"1"	"1"	"321"	"34.0"	"6.14"	"414.83"	""	"1"	""	"other metabolic processes;other biological processes"	"other cell component"	"other molecular function"	"Pf13242, Pf13344"	"283871"	"ENSG00000184207"	"PGP"	"A6NDG6; hsa:283871"	"Glycolysis"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UNZ5"	"Leydig cell tumor 10 kDa protein homolog OS=Homo sapiens OX=9606 GN=C19orf53 PE=1 SV=1"	"10"	"1"	"1"	"1"	"99"	"10.6"	"11.55"	"384.32"	""	"1"	""	""	""	""	"Pf09495"	"28974"	"ENSG00000104979"	"C19orf53"	"B2R4J9; hsa:28974; Q9UNZ5"	""	""	"0"	"0"	"5.7"	"4.1"	"10.8"	"3.6"	"4.3"	"5.0"	"79.5"	"11.6"	"22.9"	"19.6"	"18.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z7F7"	"39S ribosomal protein L55, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL55 PE=1 SV=1"	"6"	"1"	"1"	"1"	"128"	"15.1"	"11.15"	"373.50"	""	"1"	""	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;other cell component"	"other molecular function"	"Pf09776"	"128308"	"ENSG00000162910"	"MRPL55"	"hsa:128308; Q5TBY3; Q5TBY6; Q6UWI8; Q7Z7F7"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"82.4"	"82.2"	"235.8"	"63.4"	"58.6"	"56.5"	"251.4"	"36.7"	"34.1"	"39.3"	"40.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13123"	"Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3"	"1"	"1"	"1"	"1"	"557"	"65.6"	"6.64"	"370.54"	""	"1"	""	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf07807, Pf07808"	"3550"	"ENSG00000113141"	"IK"	"hsa:3550; Q13123; Q6IPD8"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"29.8"	"30.0"	"99.9"	"28.5"	"30.2"	"22.8"	"139.5"	"24.1"	"44.6"	"25.4"	"33.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P287"	"BRCA2 and CDKN1A-interacting protein OS=Homo sapiens OX=9606 GN=BCCIP PE=1 SV=1"	"5"	"1"	"1"	"1"	"314"	"36.0"	"4.61"	"360.63"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus"	"enzyme regulator activity;cytoskeletal activity"	"Pf13862"	"56647"	"ENSG00000107949"	"BCCIP"	"B3KP45; hsa:56647; Q8ND15; Q96GC4; Q9P287; Q9P288"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q2TAA2"	"Isoamyl acetate-hydrolyzing esterase 1 homolog OS=Homo sapiens OX=9606 GN=IAH1 PE=1 SV=1"	"5"	"1"	"1"	"1"	"248"	"27.6"	"5.30"	"360.29"	""	"1"	""	"other metabolic processes"	""	"other molecular function"	"Pf13472"	"285148"	"ENSG00000134330"	"IAH1"	"B4DMV3; hsa:285148; Q2TAA2"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q15051"	"IQ calmodulin-binding motif-containing protein 1 OS=Homo sapiens OX=9606 GN=IQCB1 PE=1 SV=1"	"2"	"1"	"1"	"1"	"598"	"68.9"	"9.10"	"350.34"	""	"1"	""	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00612"	"9657"	"ENSG00000173226"	"IQCB1"	"hsa:9657; Q15051; Q3KS08; Q3KS09; Q5DKQ7; Q8NI79; Q9BS08"	"Anchoring of the basal body to the plasma membrane"	"Ciliary landscape; Ciliopathies; Bardet-Biedl syndrome"	"4"	"0"	"10.3"	"11.8"	"42.7"	"10.8"	"8.3"	"8.2"	"39.1"	"4.5"	"3.8"	"3.7"	"3.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BRR8"	"G patch domain-containing protein 1 OS=Homo sapiens OX=9606 GN=GPATCH1 PE=1 SV=1"	"1"	"1"	"1"	"1"	"931"	"103.3"	"7.05"	"349.42"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf01585, Pf07713"	"55094"	"ENSG00000076650"	"GPATCH1"	"hsa:55094; Q8IZV6; Q8N3B7; Q9BRR8; Q9NW94"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05204"	"Non-histone chromosomal protein HMG-17 OS=Homo sapiens OX=9606 GN=HMGN2 PE=1 SV=3"	"20"	"1"	"1"	"1"	"90"	"9.4"	"9.99"	"348.86"	""	"1"	""	"cell organization and biogenesis;stress response;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01101"	"3151"	"ENSG00000198830"	"HMGN2"	"hsa:3151; P05204; Q0VGD5; Q6FGI5; Q96C64"	""	""	"0"	"0"	"23.3"	"9.2"	"22.3"	"11.8"	"4.5"	"4.1"	"45.3"	"9.3"	"12.3"	"21.0"	"10.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UHL0"	"ATP-dependent RNA helicase DDX25 OS=Homo sapiens OX=9606 GN=DDX25 PE=1 SV=2"	"2"	"1"	"1"	"1"	"483"	"54.7"	"6.28"	"347.50"	""	"1"	""	"other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"29118"	"ENSG00000109832"	"DDX25"	"B2R6Z0; hsa:29118; Q5XVN2; Q86W81; Q8IYP1; Q9UHL0"	""	""	"0"	"0"	"13.8"	"14.0"	"144.8"	"13.3"	"1.4"	"2.9"	"88.0"	"5.9"	"4.7"	"2.3"	"2.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P15336"	"Cyclic AMP-dependent transcription factor ATF-2 OS=Homo sapiens OX=9606 GN=ATF2 PE=1 SV=4"	"3"	"1"	"1"	"1"	"505"	"54.5"	"7.88"	"340.92"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00170"	"1386"	"ENSG00000115966"	"ATF2"	"A1L3Z2; A4D7U4; A4D7U5; A4D7V1; D3DPE9; G8JLM5; hsa:1386; P15336; Q13000; Q3B7B7; Q4ZFU9; Q53RY2; Q8TAR1; Q96JT8"	"Estrogen-dependent gene expression; HATs acetylate histones; NGF-stimulated transcription; Heme signaling; Regulation of PTEN gene transcription; TP53 Regulates Transcription of DNA Repair Genes; Circadian Clock; Transcriptional activation of mitochondrial biogenesis; Activation of the AP-1 family of transcription factors; Response of EIF2AK4 (GCN2) to amino acid deficiency"	"Energy metabolism; IL-1 signaling pathway; B cell receptor signaling pathway; AGE/RAGE pathway; ATM signaling pathway; Interleukin-1 (IL-1) structural pathway; Myometrial relaxation and contraction pathways; MAPK signaling pathway; ATM signaling in development and disease ; VEGFA-VEGFR2 signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; IL-4 signaling pathway; DNA IR-double strand breaks and cellular response via ATM; Ethanol effects on histone modifications; p38 MAPK signaling pathway; PI3K-Akt signaling pathway; Thermogenesis; Gastrin signaling pathway; Hepatitis B infection; Thyroid hormones production and peripheral downstream signaling effects; Host-pathogen interaction of human coronaviruses - MAPK signaling; Pleural mesothelioma; T-cell receptor signaling pathway"	"33"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9NRX4"	"14 kDa phosphohistidine phosphatase OS=Homo sapiens OX=9606 GN=PHPT1 PE=1 SV=1"	"7"	"1"	"1"	"1"	"125"	"13.8"	"6.07"	"337.89"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf05005"	"29085"	"ENSG00000054148"	"PHPT1"	"B1AMX0; B1AMX1; hsa:29085; Q9H0Y3; Q9NRX4"	""	""	"0"	"0"	"8.9"	"17.1"	"67.0"	"18.7"	"10.8"	"9.5"	"89.7"	"6.0"	"7.8"	"8.7"	"6.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3A3"	"MOB-like protein phocein OS=Homo sapiens OX=9606 GN=MOB4 PE=1 SV=1"	"4"	"1"	"1"	"1"	"225"	"26.0"	"5.78"	"335.80"	""	"1"	""	""	"other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf03637"	"25843"	"ENSG00000115540"	"MOB4"	"B4DML0; hsa:25843; Q53SE0; Q7Z4Y6; Q9H2P3; Q9H5J1; Q9Y3A3; Q9Y4T8"	""	""	"0"	"0"	"18.5"	"21.9"	"55.2"	"15.8"	"11.4"	"14.4"	"71.6"	"12.4"	"16.3"	"22.9"	"35.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q53GG5"	"PDZ and LIM domain protein 3 OS=Homo sapiens OX=9606 GN=PDLIM3 PE=1 SV=1"	"4"	"1"	"1"	"1"	"364"	"39.2"	"6.89"	"328.81"	""	"1"	""	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412, Pf00595, Pf15936"	"27295"	"ENSG00000154553"	"PDLIM3"	"B2R866; hsa:27295; O43590; O60439; O60440; Q53GG5; Q8N6Y6; Q9BVP4"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9HC36"	"rRNA methyltransferase 3, mitochondrial OS=Homo sapiens OX=9606 GN=MRM3 PE=1 SV=2"	"3"	"1"	"1"	"1"	"420"	"47.0"	"8.73"	"325.46"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00588"	"55178"	"ENSG00000171861"	"MRM3"	"hsa:55178; Q53GN1; Q86VC3; Q96F76; Q9HC36; Q9NVQ5"	"rRNA modification in the mitochondrion"	""	"1"	"0"	"10.5"	"8.1"	"22.5"	"12.2"	"12.5"	"9.9"	"46.2"	"7.3"	"13.8"	"12.6"	"11.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A8K8P3"	"Protein SFI1 homolog OS=Homo sapiens OX=9606 GN=SFI1 PE=1 SV=2"	"1"	"1"	"1"	"1"	"1242"	"147.6"	"10.81"	"324.81"	""	"1"	""	""	"cytosol;cytoskeleton"	"other molecular function"	""	"9814"	"ENSG00000198089"	"SFI1"	"A1L373; A1L387; A2A2L2; A8K8P3; B1AKL9; B5MDB7; B7Z1V6; B7Z8G3; B7ZBE2; B7ZBE3; hsa:9814; O60289; Q2TAN8; Q5W1B5; Q86TK0; Q8N4U8; Q8N8C1; Q8WU14"	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	""	"7"	"0"	"2.9"	"7.3"	"16.4"	"5.6"	"1.8"	"5.3"	"26.6"	"15.5"	"19.4"	"24.8"	"25.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKB3"	"DnaJ homolog subfamily C member 12 OS=Homo sapiens OX=9606 GN=DNAJC12 PE=1 SV=1"	"6"	"1"	"1"	"1"	"198"	"23.4"	"5.71"	"324.33"	""	"1"	""	""	"other cell component"	""	"Pf00226"	"56521"	"ENSG00000108176"	"DNAJC12"	"hsa:56521; Q5JVQ1; Q9UKB2; Q9UKB3"	""	""	"0"	"0"	"41.6"	"58.3"	"165.2"	"76.0"	"90.0"	"73.2"	"177.1"	"38.5"	"64.9"	"59.2"	"61.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y365"	"START domain-containing protein 10 OS=Homo sapiens OX=9606 GN=STARD10 PE=1 SV=2"	"5"	"1"	"1"	"1"	"291"	"33.0"	"7.12"	"323.29"	""	"1"	""	"transport"	"other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf01852"	"10809"	"ENSG00000214530"	"STARD10"	"hsa:10809; O60532; Q9Y365"	"Synthesis of PC"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00625"	"Pirin OS=Homo sapiens OX=9606 GN=PIR PE=1 SV=1"	"3"	"1"	"1"	"1"	"290"	"32.1"	"6.92"	"321.46"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf02678, Pf05726"	"8544"	"ENSG00000087842"	"PIR"	"hsa:8544; O00625; Q5U0G0; Q6FHD2"	"Digestion"	""	"1"	"0"	"20.8"	"18.7"	"89.9"	"13.3"	"20.1"	"13.8"	"180.1"	"22.4"	"19.1"	"15.4"	"14.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BYT8"	"Neurolysin, mitochondrial OS=Homo sapiens OX=9606 GN=NLN PE=1 SV=1"	"1"	"1"	"1"	"1"	"704"	"80.6"	"6.64"	"320.67"	""	"1"	""	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;mitochondrion"	"other molecular function"	"Pf01432"	"57486"	"ENSG00000123213"	"NLN"	"hsa:57486; Q9BYT8; Q9ULJ4"	"Peptide ligand-binding receptors"	""	"1"	"0"	"17.4"	"24.5"	"126.4"	"19.6"	"13.7"	"12.3"	"97.4"	"7.7"	"8.3"	"10.3"	"5.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15833"	"Syntaxin-binding protein 2 OS=Homo sapiens OX=9606 GN=STXBP2 PE=1 SV=2"	"3"	"1"	"1"	"1"	"593"	"66.4"	"6.55"	"310.43"	""	"1"	""	"cell-cell signaling;stress response;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00995"	"6813"	"ENSG00000076944"	"STXBP2"	"B4E175; E7EQD5; hsa:6813; Q15833; Q9BU65"	"Platelet degranulation ; Other interleukin signaling"	"Splicing factor NOVA regulated synaptic proteins; Insulin signaling"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q6UX53"	"Methyltransferase-like protein 7B OS=Homo sapiens OX=9606 GN=METTL7B PE=1 SV=2"	"5"	"1"	"1"	"1"	"244"	"27.8"	"8.38"	"305.27"	""	"1"	""	"other metabolic processes"	"other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf08241"	"196410"	"ENSG00000170439"	"TMT1B"	"A8K247; hsa:196410; Q6UX53; Q8WUI1"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14160"	"Protein scribble homolog OS=Homo sapiens OX=9606 GN=SCRIB PE=1 SV=4"	"1"	"1"	"1"	"1"	"1630"	"174.8"	"5.07"	"302.91"	""	"1"	""	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"9.5"	"11.1"	"35.0"	"11.8"	"9.8"	"8.7"	"55.4"	"10.8"	"15.2"	"8.2"	"14.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q641Q2"	"WASH complex subunit 2A OS=Homo sapiens OX=9606 GN=WASHC2A PE=1 SV=3"	"1"	"1"	"1"	"1"	"1341"	"147.1"	"4.81"	"299.83"	""	"1"	""	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf15255"	"387680"	"ENSG00000099290"	"WASHC2A"	"A2A3S2; A2A3U6; hsa:387680; Q5SNT6; Q641Q2; Q6DHY0"	""	"10q11.21q11.23 copy number variation syndrome"	"1"	"0"	"42.6"	"26.9"	"86.3"	"23.7"	"24.5"	"20.5"	"65.8"	"14.0"	"20.2"	"17.8"	"11.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86U44"	"N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2"	"3"	"1"	"1"	"1"	"580"	"64.4"	"6.42"	"298.90"	""	"1"	""	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05063"	"56339"	"ENSG00000165819"	"METTL3"	"hsa:56339; O14736; Q86U44; Q86V05; Q9HB32"	"Processing of Capped Intron-Containing Pre-mRNA"	"mRNA processing"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96S15"	"GATOR complex protein WDR24 OS=Homo sapiens OX=9606 GN=WDR24 PE=1 SV=2"	"1"	"1"	"1"	"1"	"790"	"88.2"	"6.52"	"298.08"	""	"1"	""	"other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	""	"Pf00400"	"84219"	"ENSG00000127580"	"WDR24"	"A2IDB8; D3DU59; hsa:84219; Q96GC7; Q96S15; Q9H0B7"	"Amino acids regulate mTORC1"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15357"	"Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 OS=Homo sapiens OX=9606 GN=INPPL1 PE=1 SV=2"	"1"	"1"	"1"	"1"	"1258"	"138.5"	"6.54"	"295.53"	""	"1"	""	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00017, Pf00536, Pf03372"	"3636"	"ENSG00000165458"	"INPPL1"	"B2RTX5; hsa:3636; O15357; Q13577; Q13578"	"Synthesis of PIPs at the plasma membrane; Interleukin receptor SHC signaling; Synthesis of IP3 and IP4 in the cytosol; Signaling by CSF1 (M-CSF) in myeloid cells"	"EGF/EGFR signaling pathway; Insulin signaling"	"6"	"0"	"10.3"	"11.5"	"47.3"	"9.0"	"7.1"	"4.3"	"53.8"	"8.9"	"3.1"	"2.5"	"7.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P42229"	"Signal transducer and activator of transcription 5A OS=Homo sapiens OX=9606 GN=STAT5A PE=1 SV=1"	"2"	"1"	"1"	"1"	"794"	"90.6"	"6.39"	"294.85"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00017, Pf01017, Pf02864, Pf02865"	"6776"	"ENSG00000126561"	"STAT5A"	"hsa:6776; P42229; Q1KLZ6"	"Signaling by cytosolic FGFR1 fusion mutants; Interleukin-3, Interleukin-5 and GM-CSF signaling; Interleukin-7 signaling; Signaling by SCF-KIT; Downstream signal transduction; Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants; Growth hormone receptor signaling; Nuclear signaling by ERBB4; Signaling by Leptin; Inactivation of CSF3 (G-CSF) signaling; Prolactin receptor signaling; Interleukin-20 family signaling; Erythropoietin activates STAT5; Signaling by FLT3 fusion proteins; Interleukin-2 signaling; Nuclear events stimulated by ALK signaling in cancer; STAT5 activation downstream of FLT3 ITD mutants; Interleukin-15 signaling; Interleukin-9 signaling; Interleukin-21 signaling; STAT5 Activation"	"IL-5 signaling pathway; Prolactin signaling pathway; IL-7 signaling pathway; IL-9 signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; AGE/RAGE pathway; Adipogenesis; Brain-derived neurotrophic factor (BDNF) signaling pathway; Mammary gland development pathway - Puberty (Stage 2 of 4); IL-3 signaling pathway; Kit receptor signaling pathway; RAC1/PAK1/p38/MMP2 pathway; Physico-chemical features and toxicity-associated pathways; TYROBP causal network in microglia; IL-4 signaling pathway; White fat cell differentiation; Non-small cell lung cancer; EGF/EGFR signaling pathway; Measles virus infection; Hepatitis B infection; IL-2 signaling pathway; 3q29 copy number variation syndrome; FOXP3 in COVID-19; Th17 cell differentiation pathway; Extrafollicular and follicular B cell activation by SARS-CoV-2; JAK-STAT signaling in the regulation of Beta-cells; EPO receptor signaling; Interferon type I signaling pathways; ErbB signaling pathway"	"51"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q96T58"	"Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1"	"0"	"1"	"1"	"1"	"3664"	"402.0"	"7.64"	"294.35"	""	"1"	""	"RNA metabolism OR transcription;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf07744"	"23013"	"ENSG00000065526"	"SPEN"	"hsa:23013; Q96T58; Q9H9A8; Q9NWH5; Q9UQ01; Q9Y556"	"RHOBTB1 GTPase cycle"	"Notch signaling pathway"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P1M0"	"Long-chain fatty acid transport protein 4 OS=Homo sapiens OX=9606 GN=SLC27A4 PE=1 SV=1"	"1"	"1"	"1"	"1"	"643"	"72.0"	"8.47"	"288.26"	""	"1"	""	"other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"transporter activity;other molecular function"	"Pf00501, Pf13193"	"10999"	"ENSG00000167114"	"SLC27A4"	"A8K2F7; hsa:10999; O95186; Q6P1M0; Q96G53"	"Transport of fatty acids; Defective SLC27A4 causes ichthyosis prematurity syndrome (IPS)"	"PPAR signaling pathway; Fatty acid transporters; Cholesterol metabolism; Fatty Acids and Lipoproteins Transport in Hepatocytes; Enterocyte cholesterol metabolism"	"7"	"0"	"28.0"	"43.6"	"127.1"	"28.0"	"21.6"	"16.9"	"116.4"	"10.0"	"15.0"	"13.7"	"11.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31350"	"Ribonucleoside-diphosphate reductase subunit M2 OS=Homo sapiens OX=9606 GN=RRM2 PE=1 SV=1"	"2"	"1"	"1"	"1"	"389"	"44.8"	"5.38"	"288.03"	""	"1"	""	"cell organization and biogenesis;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00268"	"6241"	"ENSG00000171848"	"RRM2"	"B2R9B5; hsa:6241; J3KP43; P31350; Q5WRU7"	"Transcriptional Regulation by E2F6; Interconversion of nucleotide di- and triphosphates; G1/S-Specific Transcription"	"Fluoropyrimidine activity; Retinoblastoma gene in cancer; Hepatitis C and hepatocellular carcinoma; Pyrimidine metabolism; Orexin receptor pathway"	"8"	"0"	"68.9"	"71.4"	"188.2"	"68.2"	"60.5"	"58.9"	"225.5"	"47.2"	"47.3"	"48.8"	"44.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5VIR6"	"Vacuolar protein sorting-associated protein 53 homolog OS=Homo sapiens OX=9606 GN=VPS53 PE=1 SV=1"	"1"	"1"	"1"	"1"	"699"	"79.6"	"6.02"	"287.46"	""	"1"	""	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"44.3"	"46.9"	"152.8"	"31.9"	"27.3"	"24.4"	"112.4"	"13.8"	"21.6"	"20.2"	"25.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35610"	"Sterol O-acyltransferase 1 OS=Homo sapiens OX=9606 GN=SOAT1 PE=1 SV=3"	"3"	"1"	"1"	"1"	"550"	"64.7"	"8.94"	"284.35"	""	"1"	""	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf03062"	"6646"	"ENSG00000057252"	"SOAT1"	"A6NC40; A8K3P4; A9Z1V7; B4DU95; hsa:6646; P35610; Q5T0X4; Q8N1E4"	"LDL clearance"	"Statin inhibition of cholesterol production; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Cholesterol metabolism"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9NVH0"	"Exonuclease 3'-5' domain-containing protein 2 OS=Homo sapiens OX=9606 GN=EXD2 PE=1 SV=2"	"2"	"1"	"1"	"1"	"621"	"70.3"	"8.32"	"281.47"	""	"1"	""	"DNA metabolism;other metabolic processes;stress response"	"other membranes;cytoskeleton;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01612"	"55218"	"ENSG00000081177"	"EXD2"	"B4DIH6; G5E947; hsa:55218; Q6AWB6; Q8N3D3; Q9NVH0"	""	""	"0"	"0"	"15.3"	"9.5"	"39.7"	"16.6"	"17.7"	"13.8"	"36.3"	"5.7"	"8.0"	"17.0"	"7.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BTY7"	"Protein HGH1 homolog OS=Homo sapiens OX=9606 GN=HGH1 PE=1 SV=1"	"3"	"1"	"1"	"1"	"390"	"42.1"	"4.81"	"280.08"	""	"1"	""	""	""	""	"Pf04063, Pf04064"	"51236"	"ENSG00000235173"	"HGH1"	"hsa:51236; P0CB43; Q9BTY7"	""	""	"0"	"0"	"28.3"	"55.6"	"142.0"	"48.0"	"44.6"	"43.7"	"128.9"	"29.1"	"27.7"	"26.6"	"30.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96IZ5"	"RNA-binding protein 41 OS=Homo sapiens OX=9606 GN=RBM41 PE=1 SV=2"	"3"	"1"	"1"	"1"	"413"	"47.1"	"8.70"	"278.85"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076"	"55285"	"ENSG00000089682"	"RBM41"	"hsa:55285; Q5JSN7; Q5JSN8; Q96IZ5; Q9H8F7; Q9NV04"	""	""	"0"	"0"	"8.8"	"10.4"	"37.3"	"7.0"	"7.6"	"5.6"	"34.1"	"2.2"	"2.5"	"3.8"	"2.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96T37"	"RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2"	"2"	"1"	"1"	"1"	"977"	"107.1"	"10.08"	"278.81"	""	"1"	""	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"other membranes;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf07744"	"64783"	"ENSG00000162775"	"RBM15"	"A1A693; hsa:64783; Q3ZB86; Q4V760; Q5D058; Q5T613; Q86VW9; Q96PE4; Q96SC5; Q96SC6; Q96SC9; Q96SD0; Q96T37; Q96T38; Q9BRA5; Q9H6R8; Q9H9Y0"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92989"	"Polyribonucleotide 5'-hydroxyl-kinase Clp1 OS=Homo sapiens OX=9606 GN=CLP1 PE=1 SV=1"	"2"	"1"	"1"	"1"	"425"	"47.6"	"6.62"	"278.80"	""	"1"	""	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus"	"kinase activity;other molecular function"	"Pf06807, Pf16573, Pf16575"	"10978"	"ENSG00000172409"	"CLP1"	"B2R7J6; B4DTI8; hsa:10978; Q92989"	"tRNA processing in the nucleus; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"mRNA processing"	"6"	"0"	"16.8"	"17.0"	"62.9"	"18.7"	"16.8"	"21.5"	"58.8"	"5.7"	"13.8"	"8.4"	"4.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z6R9"	"Transcription factor AP-2-delta OS=Homo sapiens OX=9606 GN=TFAP2D PE=1 SV=1"	"2"	"1"	"1"	"1"	"452"	"49.5"	"8.16"	"278.09"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03299"	"83741"	"ENSG00000008197"	"TFAP2D"	"hsa:83741; Q7Z6R9; Q8IWX0"	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors; Activation of the TFAP2 (AP-2) family of transcription factors"	"Ciliary landscape"	"3"	"0"	"1957.2"	"876.6"	"478.0"	"353.0"	"119.3"	"130.8"	"249.1"	"115.8"	"45.9"	"45.0"	"61.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P12931"	"Proto-oncogene tyrosine-protein kinase Src OS=Homo sapiens OX=9606 GN=SRC PE=1 SV=3"	"2"	"1"	"1"	"1"	"536"	"59.8"	"7.42"	"278.02"	""	"1"	""	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;kinase activity;other molecular function"	"Pf00017, Pf00018, Pf07714"	"6714"	"ENSG00000197122"	"SRC"	"E1P5V4; hsa:6714; P12931; Q76P87; Q86VB9; Q9H5A8"	"G alpha (i) signalling events; Extra-nuclear estrogen signaling; GPER1 signaling; PIP3 activates AKT signaling; Signaling by BRAF and RAF1 fusions; Regulation of RUNX3 expression and activity; RHOU GTPase cycle; Constitutive Signaling by Aberrant PI3K in Cancer; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; DCC mediated attractive signaling; Downstream signal transduction; Signaling by ERBB2; Nuclear signaling by ERBB4; RAF activation; GAB1 signalosome; MET activates PTK2 signaling; Signaling by CSF1 (M-CSF) in myeloid cells; RUNX2 regulates osteoblast differentiation; Long-term potentiation; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; InlA-mediated entry of Listeria monocytogenes into host cells; Regulation of commissural axon pathfinding by SLIT and ROBO; Netrin mediated repulsion signals; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; GRB2:SOS provides linkage to MAPK signaling for Integrins ; p130Cas linkage to MAPK signaling for integrins; Activated NTRK2 signals through FYN; Downregulation of ERBB4 signaling; Regulation of RUNX1 Expression and Activity; Activated NTRK3 signals through PI3K"	"Androgen receptor signaling pathway; Angiogenesis; Integrin-mediated cell adhesion; RANKL/RANK signaling pathway; Thyroid stimulating hormone (TSH) signaling pathway; Leptin signaling pathway; Follicle stimulating hormone (FSH) signaling pathway; Prolactin signaling pathway; Microtubule cytoskeleton regulation; Thymic stromal lymphopoietin (TSLP) signaling pathway; Glioblastoma signaling pathways; AGE/RAGE pathway; Interleukin-11 signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Alpha 6 beta 4 signaling pathway; Aryl hydrocarbon receptor pathway; Bladder cancer; IL-3 signaling pathway; Aryl hydrocarbon receptor pathway; Pregnane X receptor pathway; Nuclear receptors meta-pathway; Kit receptor signaling pathway; Focal adhesion; Hepatocyte growth factor receptor signaling; RAC1/PAK1/p38/MMP2 pathway; Amplification and expansion of oncogenic pathways as metastatic traits; Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; Robo4 and VEGF signaling pathways crosstalk; Fibrin complement receptor 3 signaling pathway; Acute viral myocarditis; NRF2-ARE regulation; EGF/EGFR signaling pathway; Relationship between inflammation, COX-2 and EGFR; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Fragile X syndrome; Gastrin signaling pathway; Hepatitis B infection; Thyroid hormones production and peripheral downstream signaling effects; Netrin-UNC5B signaling pathway; EGFR tyrosine kinase inhibitor resistance; Pleural mesothelioma; CCL18 signaling pathway; GDNF signaling; TROP2 regulatory signaling; A network map of Macrophage-stimulating protein (MSP) signaling; EPO receptor signaling; Notch signaling pathway; ErbB signaling pathway"	"86"	"0"	"15.3"	"19.6"	"63.5"	"18.4"	"16.2"	"11.4"	"95.2"	"17.6"	"18.6"	"16.4"	"13.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61019"	"Ras-related protein Rab-2A OS=Homo sapiens OX=9606 GN=RAB2A PE=1 SV=1"	"4"	"1"	"1"	"1"	"212"	"23.5"	"6.54"	"277.96"	""	"1"	""	"cell organization and biogenesis;transport"	"other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00071"	"5862"	"ENSG00000104388"	"RAB2A"	"B2R5W8; B4DMQ5; hsa:5862; P08886; P61019"	"RAB geranylgeranylation; Golgi Cisternae Pericentriolar Stack Reorganization"	"Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Ciliary landscape"	"4"	"0"	"60.5"	"63.3"	"395.8"	"52.3"	"48.8"	"46.5"	"499.4"	"30.1"	"49.2"	"33.7"	"33.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86VU5"	"Catechol O-methyltransferase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=COMTD1 PE=1 SV=1"	"6"	"1"	"1"	"1"	"262"	"28.8"	"8.38"	"276.66"	""	"1"	""	"other metabolic processes"	"other membranes"	"other molecular function"	"Pf01596"	"118881"	"ENSG00000165644"	"COMTD1"	"hsa:118881; Q86VU5; Q8TE79"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3D6"	"Mitochondrial fission 1 protein OS=Homo sapiens OX=9606 GN=FIS1 PE=1 SV=2"	"7"	"1"	"1"	"1"	"152"	"16.9"	"8.79"	"276.14"	""	"1"	""	"cell organization and biogenesis;other metabolic processes;transport;signal transduction;other biological processes"	"other membranes;cytosol;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf14852, Pf14853"	"51024"	"ENSG00000214253"	"FIS1"	"hsa:51024; Q9BTP3; Q9Y3D6"	"Class I peroxisomal membrane protein import"	"CAMKK2 pathway"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IY18"	"Structural maintenance of chromosomes protein 5 OS=Homo sapiens OX=9606 GN=SMC5 PE=1 SV=2"	"1"	"1"	"1"	"1"	"1101"	"128.7"	"8.38"	"274.95"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02463"	"23137"	"ENSG00000198887"	"SMC5"	"A6NM81; hsa:23137; O60335; Q05D92; Q5VZ60; Q8IY18; Q96SB9"	"SUMOylation of DNA damage response and repair proteins"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"O75391"	"Sperm-associated antigen 7 OS=Homo sapiens OX=9606 GN=SPAG7 PE=1 SV=2"	"3"	"1"	"1"	"1"	"227"	"26.0"	"7.91"	"274.28"	""	"1"	""	""	"nucleus"	"nucleic acid binding activity"	"Pf01424"	"9552"	"ENSG00000091640"	"SPAG7"	"hsa:9552; O75391; Q96EU5"	""	""	"0"	"0"	"92.6"	"103.4"	"334.6"	"111.1"	"113.9"	"104.8"	"444.8"	"66.0"	"155.3"	"129.6"	"147.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7L266"	"Isoaspartyl peptidase/L-asparaginase OS=Homo sapiens OX=9606 GN=ASRGL1 PE=1 SV=2"	"3"	"1"	"1"	"1"	"308"	"32.0"	"6.24"	"273.56"	""	"1"	""	"protein metabolism;other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf01112"	"80150"	"ENSG00000162174"	"ASRGL1"	"B2R7Q0; hsa:80150; Q567Q4; Q6P1P0; Q7L266; Q8NI34; Q9H6F7"	"Phenylalanine metabolism"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95219"	"Sorting nexin-4 OS=Homo sapiens OX=9606 GN=SNX4 PE=1 SV=1"	"3"	"1"	"1"	"1"	"450"	"51.9"	"5.99"	"273.26"	""	"1"	""	"transport;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00787"	"8723"	"ENSG00000114520"	"SNX4"	"B3KMH0; B4DQV4; D3DNA3; hsa:8723; O95219"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WVT3"	"Trafficking protein particle complex subunit 12 OS=Homo sapiens OX=9606 GN=TRAPPC12 PE=1 SV=3"	"1"	"1"	"1"	"1"	"735"	"79.3"	"4.91"	"271.76"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	""	"Pf14559"	"51112"	"ENSG00000171853"	"TRAPPC12"	"B3KV01; D6W4Y2; hsa:51112; Q8WVT3; Q8WVW1; Q9Y395"	"RAB GEFs exchange GTP for GDP on RABs"	""	"1"	"0"	"7.0"	"10.4"	"32.0"	"4.7"	"6.1"	"4.6"	"25.2"	"2.7"	"9.4"	"9.5"	"17.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EL3"	"39S ribosomal protein L53, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL53 PE=1 SV=1"	"13"	"1"	"1"	"1"	"112"	"12.1"	"8.76"	"271.02"	""	"1"	""	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	""	"Pf10780"	"116540"	"ENSG00000204822"	"MRPL53"	"hsa:116540; Q96EL3"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"25.3"	"22.2"	"55.2"	"29.5"	"24.2"	"23.9"	"49.2"	"9.2"	"22.5"	"11.7"	"10.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P10619"	"Lysosomal protective protein OS=Homo sapiens OX=9606 GN=CTSA PE=1 SV=2"	"2"	"1"	"1"	"1"	"480"	"54.4"	"6.61"	"270.09"	""	"1"	""	"protein metabolism;transport;other biological processes"	"non-structural extracellular;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00450"	"5476"	"ENSG00000064601"	"CTSA"	"B2R798; hsa:5476; P10619; Q561W6; Q5JZH1; Q96KJ2; Q9BR08; Q9BW68"	"MHC class II antigen presentation; Neutrophil degranulation; Glycosphingolipid metabolism; Sialic acid metabolism; Defective NEU1 causes sialidosis"	"Ciliary landscape"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q15036"	"Sorting nexin-17 OS=Homo sapiens OX=9606 GN=SNX17 PE=1 SV=1"	"3"	"1"	"1"	"1"	"470"	"52.9"	"7.46"	"269.21"	""	"1"	""	"other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00787, Pf18116"	"9784"	"ENSG00000115234"	"SNX17"	"B4DQM7; hsa:9784; Q15036; Q53HN7; Q6IAS3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"P42566"	"Epidermal growth factor receptor substrate 15 OS=Homo sapiens OX=9606 GN=EPS15 PE=1 SV=2"	"1"	"1"	"1"	"1"	"896"	"98.6"	"4.64"	"267.70"	""	"1"	""	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	""	"2060"	"ENSG00000085832"	"EPS15"	"B2R8J7; D3DPJ2; hsa:2060; P42566; Q5SRH4"	"Cargo recognition for clathrin-mediated endocytosis; EGFR downregulation; Negative regulation of MET activity; InlB-mediated entry of Listeria monocytogenes into host cell"	"VEGFA-VEGFR2 signaling; Ebola virus infection in host; EGF/EGFR signaling pathway"	"8"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3D2"	"Methionine-R-sulfoxide reductase B2, mitochondrial OS=Homo sapiens OX=9606 GN=MSRB2 PE=1 SV=2"	"6"	"1"	"1"	"1"	"182"	"19.5"	"8.63"	"263.57"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response"	"cytosol;mitochondrion;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01641"	"22921"	"ENSG00000148450"	"MSRB2"	"hsa:22921; Q17R44; Q4G1C7; Q9Y3D2; Q9Y5W6"	"Protein repair"	"Sulindac metabolic pathway; Methionine de novo and salvage pathway"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43681"	"ATPase GET3 OS=Homo sapiens OX=9606 GN=GET3 PE=1 SV=2"	"2"	"1"	"1"	"1"	"348"	"38.8"	"4.91"	"261.16"	""	"1"	""	"cell organization and biogenesis;transport;other biological processes"	"other membranes;ER/Golgi;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf02374"	"439"	"ENSG00000198356"	"GET3"	"A6NHP8; A8K740; hsa:439; O43681; Q53FC6; Q92849"	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"	""	"1"	"0"	"64.0"	"101.6"	"234.4"	"86.0"	"76.7"	"75.1"	"272.5"	"57.2"	"72.5"	"69.4"	"62.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NX07"	"tRNA selenocysteine 1-associated protein 1 OS=Homo sapiens OX=9606 GN=TRNAU1AP PE=1 SV=1"	"2"	"1"	"1"	"1"	"287"	"32.5"	"4.74"	"259.77"	""	"1"	""	"protein metabolism;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf17654"	"54952"	"ENSG00000180098"	"TRNAU1AP"	"hsa:54952; Q86SU7; Q9NX07"	""	""	"0"	"0"	"9.6"	"18.6"	"49.2"	"17.3"	"18.3"	"16.3"	"57.1"	"7.9"	"11.5"	"8.8"	"8.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96S55"	"ATPase WRNIP1 OS=Homo sapiens OX=9606 GN=WRNIP1 PE=1 SV=2"	"2"	"1"	"1"	"1"	"665"	"72.1"	"6.10"	"258.22"	""	"1"	""	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00004, Pf12002, Pf16193, Pf18279"	"56897"	"ENSG00000124535"	"WRNIP1"	"B2RDB0; hsa:56897; Q53EP6; Q59ET8; Q5W0E2; Q5W0E4; Q8WV26; Q96S55; Q9H681; Q9NRJ6"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9BUL5"	"PHD finger protein 23 OS=Homo sapiens OX=9606 GN=PHF23 PE=1 SV=1"	"3"	"1"	"1"	"1"	"403"	"43.8"	"5.78"	"257.33"	""	"1"	""	"other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00628"	"79142"	"ENSG00000040633"	"PHF23"	"A1DZ74; B3KVH8; B4DLK6; D3DTN4; hsa:79142; Q8IZK0; Q96HG7; Q9BUL5; Q9H5X0"	""	""	"0"	"0"	"3.6"	"5.6"	"17.3"	"11.0"	"7.5"	"3.4"	"37.1"	"9.1"	"8.8"	"4.3"	"5.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UPP2"	"IQ motif and SEC7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=IQSEC3 PE=2 SV=3"	"1"	"1"	"1"	"1"	"1182"	"127.5"	"6.51"	"257.29"	""	"1"	""	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf01369, Pf16453"	"440073"	"ENSG00000120645; ENSG00000262607"	"IQSEC3"	"A6NIF2; A6NKV9; hsa:440073; Q8TB43; Q9UPP2"	"NPAS4 regulates expression of target genes"	""	"1"	"0"	"18.2"	"14.7"	"49.8"	"18.1"	"10.6"	"11.6"	"45.9"	"13.9"	"22.6"	"23.8"	"39.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q969Z3"	"Mitochondrial amidoxime reducing component 2 OS=Homo sapiens OX=9606 GN=MTARC2 PE=1 SV=1"	"2"	"1"	"1"	"1"	"335"	"38.0"	"9.16"	"256.17"	""	"1"	""	"other metabolic processes;stress response;other biological processes"	"other membranes;mitochondrion;other cytoplasmic organelle"	"other molecular function"	"Pf03473, Pf03476"	"54996"	"ENSG00000117791"	"MTARC2"	"B2D0R5; D3DTB3; hsa:54996; Q0JSK7; Q5VT67; Q5VXC7; Q7L317; Q969Z3; Q9H066; Q9NWU0"	"Phase I - Functionalization of compounds"	""	"1"	"0"	"25.4"	"24.5"	"104.9"	"15.6"	"15.3"	"13.6"	"68.8"	"5.7"	"9.3"	"5.8"	"6.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P16278"	"Beta-galactosidase OS=Homo sapiens OX=9606 GN=GLB1 PE=1 SV=2"	"2"	"1"	"1"	"1"	"677"	"76.0"	"6.57"	"255.89"	""	"1"	""	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01301, Pf13364"	"2720"	"ENSG00000170266"	"GLB1"	"B2R7H8; B7Z6B0; hsa:2720; P16278; P16279"	"Neutrophil degranulation; Glycosphingolipid metabolism; HS-GAG degradation; Sialic acid metabolism; Keratan sulfate degradation; Defective NEU1 causes sialidosis; MPS IV - Morquio syndrome B"	"Ectoderm differentiation; Degradation pathway of sphingolipids, including diseases; Ciliary landscape; Glycosaminoglycan degradation; Sphingolipid metabolism in senescence"	"12"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13613"	"Myotubularin-related protein 1 OS=Homo sapiens OX=9606 GN=MTMR1 PE=1 SV=4"	"1"	"1"	"1"	"1"	"665"	"74.6"	"7.14"	"255.88"	""	"1"	""	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf02893, Pf06602"	"8776"	"ENSG00000063601"	"MTMR1"	"A0A024RC07; hsa:8776; Q13613; Q9UBX6; Q9UEM0; Q9UQD5"	"RHOF GTPase cycle; Synthesis of PIPs at the plasma membrane"	""	"2"	"0"	"40.2"	"68.1"	"145.6"	"53.0"	"55.4"	"43.9"	"143.8"	"45.7"	"96.9"	"141.6"	"170.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BYD6"	"39S ribosomal protein L1, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL1 PE=1 SV=2"	"2"	"1"	"1"	"1"	"325"	"36.9"	"8.78"	"255.75"	""	"1"	""	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00687"	"65008"	"ENSG00000169288"	"MRPL1"	"A6NG03; hsa:65008; Q4W5B8; Q6IAG4; Q96BW3; Q9BYD6; Q9H793; Q9NRL5"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"152.3"	"132.5"	"377.8"	"142.3"	"127.5"	"121.4"	"356.3"	"73.2"	"130.4"	"143.2"	"259.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13228"	"Methanethiol oxidase OS=Homo sapiens OX=9606 GN=SELENBP1 PE=1 SV=2"	"2"	"1"	"1"	"1"	"472"	"52.4"	"6.37"	"255.72"	""	"1"	""	"transport"	"other membranes;cytosol;nucleus"	"other molecular function"	"Pf05694"	"8991"	"ENSG00000143416"	"SELENBP1"	"A6NML9; A6PVW9; B2RDR3; B4DKP6; B4E1F3; hsa:8991; Q13228; Q49AQ8; Q96GX7"	""	"IL1 and megakaryocytes in obesity"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q8NFH5"	"Nucleoporin NUP35 OS=Homo sapiens OX=9606 GN=NUP35 PE=1 SV=1"	"2"	"1"	"1"	"1"	"326"	"34.8"	"9.09"	"255.51"	""	"1"	""	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf05172"	"129401"	"ENSG00000163002"	"NUP35"	"B4DP57; B4DYB4; hsa:129401; Q4ZFZ9; Q53S95; Q8NFH5; Q8TDJ1"	"ISG15 antiviral mechanism; SARS-CoV-2 activates/modulates innate and adaptive immune responses; tRNA processing in the nucleus; HCMV Late Events; HCMV Early Events; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); Postmitotic nuclear pore complex (NPC) reformation"	""	"29"	"0"	"12.0"	"13.6"	"51.4"	"17.1"	"14.6"	"10.7"	"58.8"	"8.8"	"14.0"	"15.9"	"16.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60759"	"Cytohesin-interacting protein OS=Homo sapiens OX=9606 GN=CYTIP PE=1 SV=2"	"2"	"1"	"1"	"1"	"359"	"40.0"	"6.99"	"255.45"	""	"1"	""	"other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	""	"Pf00595"	"9595"	"ENSG00000115165"	"CYTIP"	"B4DWH9; hsa:9595; O60759; Q15630; Q8NE32"	""	"Amplification and expansion of oncogenic pathways as metastatic traits"	"1"	"0"	"19.4"	"18.0"	"56.5"	"15.9"	"10.8"	"10.3"	"77.1"	"9.6"	"22.0"	"17.6"	"14.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50851"	"Lipopolysaccharide-responsive and beige-like anchor protein OS=Homo sapiens OX=9606 GN=LRBA PE=1 SV=4"	"0"	"1"	"1"	"1"	"2863"	"318.9"	"5.60"	"255.19"	""	"1"	""	"cell organization and biogenesis;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle"	"other molecular function"	"Pf02138, Pf06469, Pf13385, Pf14844, Pf15787, Pf20425, Pf20426"	"987"	"ENSG00000198589"	"LRBA"	"hsa:987; P50851; Q4W5J4; Q4W5L6; Q8NFQ0; Q9H2U3; Q9H2U4"	""	""	"0"	"0"	"33.0"	"36.4"	"143.3"	"28.4"	"15.5"	"12.8"	"93.7"	"5.0"	"14.7"	"8.2"	"7.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P18583"	"Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4"	"0"	"1"	"1"	"1"	"2426"	"263.7"	"5.64"	"255.13"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf01585, Pf14709, Pf17069"	"6651"	"ENSG00000159140"	"SON"	"D3DSF5; D3DSF6; E7ETE8; E7EU67; E7EVW3; E9PFQ2; hsa:6651; O14487; O95981; P18583; Q14120; Q6PKE0; Q9H7B1; Q9P070; Q9P072; Q9UKP9; Q9UPY0"	""	""	"0"	"0"	"25.2"	"28.7"	"92.0"	"22.2"	"28.3"	"24.6"	"110.9"	"17.8"	"35.1"	"27.9"	"30.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WV99"	"AN1-type zinc finger protein 2B OS=Homo sapiens OX=9606 GN=ZFAND2B PE=1 SV=1"	"3"	"1"	"1"	"1"	"257"	"28.0"	"6.92"	"254.97"	""	"1"	""	"protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf01428, Pf02809"	"130617"	"ENSG00000158552"	"ZFAND2B"	"hsa:130617; Q8NB98; Q8WV99"	""	""	"0"	"0"	"9.7"	"16.0"	"37.7"	"20.7"	"17.4"	"17.0"	"42.3"	"10.9"	"9.3"	"9.0"	"10.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04637"	"Cellular tumor antigen p53 OS=Homo sapiens OX=9606 GN=TP53 PE=1 SV=4"	"2"	"1"	"1"	"1"	"393"	"43.6"	"6.79"	"253.88"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00870, Pf07710, Pf08563, Pf18521"	"7157"	"ENSG00000141510"	"TP53"	"hsa:7157; P04637; Q15086; Q15087; Q15088; Q16535; Q16807; Q16808; Q16809; Q16810; Q16811; Q16848; Q2XN98; Q3LRW1; Q3LRW2; Q3LRW3; Q3LRW4; Q3LRW5; Q86UG1; Q8J016; Q99659; Q9BTM4; Q9HAQ8; Q9NP68; Q9NPJ2; Q9NZD0; Q9UBI2; Q9UQ61"	"TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest; Autodegradation of the E3 ubiquitin ligase COP1; Ub-specific processing proteases; The role of GTSE1 in G2/M progression after G2 checkpoint; TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain; Regulation of TP53 Degradation; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; TP53 Regulates Transcription of Death Receptors and Ligands; Oxidative Stress Induced Senescence; Regulation of PTEN gene transcription; TP53 Regulates Transcription of DNA Repair Genes; Regulation of TP53 Activity through Phosphorylation; TP53 Regulates Metabolic Genes; Association of TriC/CCT with target proteins during biosynthesis; Interleukin-4 and Interleukin-13 signaling; Pre-NOTCH Transcription and Translation; Oncogene Induced Senescence; Transcriptional Regulation by VENTX; Factors involved in megakaryocyte development and platelet production; TP53 Regulates Transcription of Caspase Activators and Caspases; Regulation of TP53 Activity through Methylation; G2/M DNA damage checkpoint; Regulation of NF-kappa B signaling; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Activation of PUMA and translocation to mitochondria; TP53 Regulates Transcription of Genes Involved in Cytochrome C Release; TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain; Regulation of TP53 Activity through Association with Co-factors; Ovarian tumor domain proteases; Pyroptosis; SUMOylation of transcription factors; Regulation of TP53 Expression; RUNX3 regulates CDKN1A transcription; Activation of NOXA and translocation to mitochondria; Formation of Senescence-Associated Heterochromatin Foci (SAHF); PI5P Regulates TP53 Acetylation; Transcriptional  activation of  cell cycle inhibitor p21 ; Loss of function of TP53 in cancer due to loss of tetramerization ability"	"AMP-activated protein kinase signaling; miRNA regulation of DNA damage response; miRNAs involved in DNA damage response; Fluoropyrimidine activity; TP53 network; Folate metabolism; Apoptosis modulation and signaling; Cell cycle; Metastatic brain tumor; Glioblastoma signaling pathways; Gastric cancer network 2; Oncostatin M signaling pathway; Spinal cord injury; Retinoblastoma gene in cancer; Amyotrophic lateral sclerosis (ALS); ATM signaling pathway; Apoptosis; Mammary gland development pathway - Involution (Stage 4 of 4); Bladder cancer; Copper homeostasis; RAC1/PAK1/p38/MMP2 pathway; Photodynamic therapy-induced HIF-1 survival signaling; Hepatitis C and hepatocellular carcinoma; Pathways affected in adenoid cystic carcinoma; lncRNA-mediated mechanisms of therapeutic resistance; MAPK signaling pathway; miRNA regulation of p53 pathway in prostate cancer; Wnt signaling pathway and pluripotency; Endometrial cancer; PI3K-Akt signaling pathway; Caloric restriction and aging; Chromosomal and microsatellite instability in colorectal cancer ; Epithelial to mesenchymal transition in colorectal cancer; Non-small cell lung cancer; Breast cancer pathway; Pancreatic adenocarcinoma pathway; Ultraconserved region 339 modulation of tumor suppressor microRNAs in cancer; Ferroptosis; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; MicroRNA network associated with chronic lymphocytic leukemia; G1 to S cell cycle control; Measles virus infection; 22q11.2 copy number variation syndrome; Small cell lung cancer; Head and neck squamous cell carcinoma; Melanoma; Thyroid hormones production and peripheral downstream signaling effects; Netrin-UNC5B signaling pathway; IL-18 signaling pathway; Unfolded protein response; 16p11.2 proximal deletion syndrome; Pentose phosphate pathway in senescent cells; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Glycolysis in senescence; TCA cycle in senescence; Pleural mesothelioma; Lipid metabolism in senescent cells; DYRK1A involvement regarding cell proliferation in brain development; 2q37 copy number variation syndrome; Autophagy in pancreatic ductal adenocarcinoma; 11p11.2 copy number variation syndrome ; A network map of Macrophage-stimulating protein (MSP) signaling; ErbB signaling pathway; DNA damage response; DNA damage response (only ATM dependent)"	"107"	"0"	"40.7"	"39.5"	"139.5"	"38.0"	"35.1"	"37.0"	"170.4"	"20.0"	"31.7"	"20.1"	"25.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6FI81"	"Anamorsin OS=Homo sapiens OX=9606 GN=CIAPIN1 PE=1 SV=2"	"3"	"1"	"1"	"1"	"312"	"33.6"	"5.62"	"253.87"	""	"1"	""	"cell organization and biogenesis;other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf05093, Pf08241"	"57019"	"ENSG00000005194"	"CIAPIN1"	"A8K8B6; hsa:57019; O75206; O75207; Q6FI81; Q9H0W1; Q9P1L7"	"Cytosolic iron-sulfur cluster assembly"	""	"1"	"0"	"8.8"	"12.8"	"55.0"	"13.4"	"8.0"	"6.1"	"79.7"	"6.5"	"6.0"	"5.4"	"6.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16854"	"Deoxyguanosine kinase, mitochondrial OS=Homo sapiens OX=9606 GN=DGUOK PE=1 SV=2"	"3"	"1"	"1"	"1"	"277"	"32.0"	"8.66"	"253.76"	""	"1"	""	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;mitochondrion;other cell component"	"kinase activity;other molecular function"	"Pf01712"	"1716"	"ENSG00000114956"	"DGUOK"	"hsa:1716; P78532; Q16759; Q16854; Q4ZG09; Q7L1W9; Q96BC1"	"Purine salvage"	"Genetic causes of porto-sinusoidal vascular disease"	"2"	"0"	"26.0"	"29.9"	"146.8"	"22.9"	"14.7"	"15.6"	"182.5"	"20.8"	"18.2"	"15.1"	"17.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A8MWX3"	"Putative WAS protein family homolog 4 OS=Homo sapiens OX=9606 GN=WASH4P PE=5 SV=1"	"1"	"1"	"1"	"1"	"477"	"51.6"	"6.67"	"253.65"	""	"1"	""	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"cytoskeletal activity"	"Pf11945"	""	""	"WASH4P"	"A8MWX3"	""	""	"0"	"0"	"47.3"	"46.8"	"130.5"	"34.0"	"23.6"	"24.8"	"64.6"	"5.8"	"11.8"	"14.0"	"13.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BVJ6"	"U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1"	"1"	"1"	"1"	"1"	"771"	"87.9"	"7.87"	"253.38"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf04615"	"10813"	"ENSG00000156697"	"UTP14A"	"A8K7A3; A8MVQ1; B4DQ08; E9PEL7; hsa:10813; Q5JYF1; Q9BVJ6"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"P40189"	"Interleukin-6 receptor subunit beta OS=Homo sapiens OX=9606 GN=IL6ST PE=1 SV=2"	"1"	"1"	"1"	"1"	"918"	"103.5"	"5.95"	"253.31"	""	"1"	""	"other metabolic processes;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00041, Pf06328, Pf09240"	"3572"	"ENSG00000134352"	"IL6ST"	"A0N0L4; hsa:3572; P40189; Q5FC04; Q9UQ41"	"Interleukin-6 signaling; IL-6-type cytokine receptor ligand interactions; Interleukin-35 Signalling; Interleukin-27 signaling"	"Physiological and pathological hypertrophy of the heart; MicroRNAs in cardiomyocyte hypertrophy; Interleukin-11 signaling pathway; Adipogenesis; Oncostatin M signaling pathway; Mammary gland development pathway - Involution (Stage 4 of 4); IL6 signaling pathway; Embryonic stem cell pluripotency pathways; ncRNAs involved in STAT3 signaling in hepatocellular carcinoma; Genes associated with the development of rheumatoid arthritis; Angiotensin II receptor type 1 pathway; Neuroinflammation and glutamatergic signaling"	"16"	"0"	"13.6"	"15.5"	"81.6"	"20.9"	"4.1"	"7.5"	"61.7"	"3.0"	"7.5"	"8.8"	"8.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z2T5"	"TRMT1-like protein OS=Homo sapiens OX=9606 GN=TRMT1L PE=1 SV=2"	"1"	"1"	"1"	"1"	"733"	"81.7"	"7.88"	"253.27"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf02005"	"81627"	"ENSG00000121486"	"TRMT1L"	"hsa:81627; Q5TEN0; Q6ZMX0; Q7Z2T5; Q8IWH5; Q8NC68; Q9BZQ1"	""	""	"0"	"0"	"42.9"	"65.9"	"169.9"	"49.6"	"46.1"	"46.5"	"193.4"	"25.3"	"40.4"	"27.1"	"24.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P12109"	"Collagen alpha-1(VI) chain OS=Homo sapiens OX=9606 GN=COL6A1 PE=1 SV=3"	"1"	"1"	"1"	"1"	"1028"	"108.5"	"5.43"	"253.20"	""	"1"	""	"cell adhesion;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;ER/Golgi;other cell component"	"extracellular structural activity;other molecular function"	"Pf00092, Pf01391"	"1291"	"ENSG00000142156"	"COL6A1"	"hsa:1291; O00117; O00118; P12109; Q14040; Q14041; Q16258; Q7Z645; Q9BSA8"	"Collagen degradation; Signaling by PDGF; Assembly of collagen fibrils and other multimeric structures; Integrin cell surface interactions; ECM proteoglycans; NCAM1 interactions; Collagen chain trimerization"	"miRNA targets in ECM and membrane receptors; PI3K-Akt signaling pathway"	"10"	"0"	"6.7"	"8.9"	"30.8"	"7.1"	"8.5"	"5.7"	"40.9"	"1.9"	"7.3"	"3.7"	"3.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P27707"	"Deoxycytidine kinase OS=Homo sapiens OX=9606 GN=DCK PE=1 SV=1"	"4"	"1"	"1"	"1"	"260"	"30.5"	"5.21"	"253.15"	""	"1"	""	"other metabolic processes"	"cytosol;mitochondrion;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf01712"	"1633"	"ENSG00000156136"	"DCK"	"B2R8V6; hsa:1633; P27707; Q5TZY7; Q6FI11"	"Pyrimidine salvage; Purine salvage"	"Retinoblastoma gene in cancer; Pyrimidine metabolism"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"O60232"	"Protein ZNRD2 OS=Homo sapiens OX=9606 GN=ZNRD2 PE=1 SV=1"	"4"	"1"	"1"	"1"	"199"	"21.5"	"5.24"	"252.83"	""	"1"	""	"cell cycle OR cell proliferation;other biological processes"	""	""	"Pf06677"	"10534"	"ENSG00000173465"	"ZNRD2"	"hsa:10534; O60232"	""	""	"0"	"0"	"86.4"	"123.8"	"415.0"	"107.6"	"96.9"	"94.5"	"456.1"	"61.3"	"79.3"	"68.5"	"64.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49770"	"Translation initiation factor eIF-2B subunit beta OS=Homo sapiens OX=9606 GN=EIF2B2 PE=1 SV=3"	"5"	"1"	"1"	"1"	"351"	"39.0"	"6.16"	"252.65"	""	"1"	""	"protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01008"	"8892"	"ENSG00000119718"	"EIF2B2"	"hsa:8892; O43201; P49770"	"Recycling of eIF2:GDP"	"Translation factors; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; Rett syndrome causing genes; Primary ovarian insufficiency"	"5"	"0"	"25.6"	"23.7"	"78.4"	"22.2"	"23.6"	"18.6"	"85.6"	"8.6"	"15.4"	"11.9"	"17.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43292"	"Glycosylphosphatidylinositol anchor attachment 1 protein OS=Homo sapiens OX=9606 GN=GPAA1 PE=1 SV=3"	"2"	"1"	"1"	"1"	"621"	"67.6"	"8.06"	"251.69"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi"	"cytoskeletal activity"	"Pf04114"	"8733"	"ENSG00000197858"	"GPAA1"	"hsa:8733; O43292; Q9NSS0; Q9UQ31"	"Attachment of GPI anchor to uPAR"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BWJ5"	"Splicing factor 3B subunit 5 OS=Homo sapiens OX=9606 GN=SF3B5 PE=1 SV=1"	"7"	"1"	"1"	"1"	"86"	"10.1"	"6.35"	"251.61"	""	"1"	""	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf07189"	"83443"	"ENSG00000169976"	"SF3B5"	"B2R568; hsa:83443; Q7RTV1; Q9BWJ5"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"mRNA processing"	"3"	"0"	"172.9"	"186.9"	"640.7"	"206.9"	"192.4"	"175.2"	"619.8"	"75.3"	"147.0"	"107.5"	"104.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6ZV70"	"LanC-like protein 3 OS=Homo sapiens OX=9606 GN=LANCL3 PE=2 SV=2"	"1"	"1"	"1"	"1"	"420"	"46.3"	"7.09"	"251.49"	""	"1"	""	"other metabolic processes"	"plasma membrane;other membranes"	""	"Pf05147"	"347404"	"ENSG00000147036"	"LANCL3"	"A6NHE3; hsa:347404; Q6ZV70"	""	""	"0"	"0"	"120.2"	"126.7"	"212.2"	"125.3"	"126.8"	"105.2"	"249.0"	"96.0"	"139.1"	"119.8"	"120.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95363"	"Phenylalanine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=FARS2 PE=1 SV=1"	"2"	"1"	"1"	"1"	"451"	"52.3"	"7.46"	"250.32"	""	"1"	""	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01409, Pf03147"	"10667"	"ENSG00000145982"	"FARS2"	"B2R664; hsa:10667; O95363; Q53F66; Q5TCS3; Q6FG29; Q9NPY7; Q9P062"	"Mitochondrial tRNA aminoacylation"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00165"	"HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2"	"2"	"1"	"1"	"1"	"279"	"31.6"	"4.92"	"249.56"	""	"1"	""	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"other molecular function"	""	"10456"	"ENSG00000143575"	"HAX1"	"A8W4W9; A8W4X0; B4DUJ7; hsa:10456; O00165; Q5VYD5; Q5VYD7; Q96AU4; Q9BS80"	""	"Primary ovarian insufficiency"	"1"	"0"	"59.7"	"64.8"	"269.6"	"58.4"	"39.2"	"29.3"	"304.1"	"17.4"	"28.1"	"22.0"	"17.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95789"	"Zinc finger MYM-type protein 6 OS=Homo sapiens OX=9606 GN=ZMYM6 PE=1 SV=2"	"0"	"1"	"1"	"1"	"1325"	"148.0"	"8.22"	"249.54"	""	"1"	""	"cell organization and biogenesis;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf06467, Pf14291"	"9204"	"ENSG00000163867"	"ZMYM6"	"B4DRJ6; hsa:9204; O95789; Q32Q23; Q4G108; Q5SVZ9; Q5SW00; Q69YL4; Q96IY0; Q9NWF1; Q9P2J4"	""	""	"0"	"0"	"169.0"	"194.1"	"522.6"	"236.1"	"158.5"	"157.5"	"294.6"	"40.2"	"64.8"	"47.9"	"74.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5J7"	"Mitochondrial import inner membrane translocase subunit Tim9 OS=Homo sapiens OX=9606 GN=TIMM9 PE=1 SV=1"	"9"	"1"	"1"	"1"	"89"	"10.4"	"7.21"	"249.40"	""	"1"	""	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf02953"	"26520"	"ENSG00000100575"	"TIMM9"	"B2R584; hsa:26520; Q9Y5J7"	"Mitochondrial protein import"	""	"1"	"0"	"63.4"	"73.1"	"196.2"	"63.6"	"61.0"	"52.2"	"189.2"	"32.3"	"45.1"	"37.6"	"45.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TDD1"	"ATP-dependent RNA helicase DDX54 OS=Homo sapiens OX=9606 GN=DDX54 PE=1 SV=2"	"1"	"1"	"1"	"1"	"881"	"98.5"	"10.02"	"248.75"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes;signal transduction"	"ER/Golgi;nucleus"	"signal transduction activity or receptor binding;other molecular function"	"Pf00270, Pf00271, Pf08147"	"79039"	"ENSG00000123064"	"DDX54"	"hsa:79039; Q86YT8; Q8TDD1; Q9BRZ1"	""	""	"0"	"0"	"16.5"	"16.4"	"68.3"	"12.6"	"14.0"	"14.2"	"45.0"	"4.6"	"6.1"	"4.2"	"3.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q4G0P3"	"Hydrocephalus-inducing protein homolog OS=Homo sapiens OX=9606 GN=HYDIN PE=1 SV=3"	"0"	"1"	"1"	"1"	"5121"	"575.5"	"6.06"	"247.34"	""	"1"	""	"cell organization and biogenesis;developmental processes;other biological processes"	"cytoskeleton"	""	"Pf15780, Pf17213"	"54768"	"ENSG00000157423; ENSG00000283022"	"HYDIN"	"A6NC70; A6NLZ0; B4DQY4; B4DRN4; F5H6V3; hsa:54768; Q4G0P3; Q8N3H8; Q8N3P6; Q8TC08; Q96JG3; Q96SS4; Q9H5U3; Q9H9B8; Q9NTI0; Q9UBE5"	""	"Ciliopathies"	"1"	"0"	"100.6"	"150.6"	"419.6"	"137.0"	"113.4"	"93.5"	"369.8"	"59.6"	"89.8"	"72.8"	"93.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15814"	"Tubulin-specific chaperone C OS=Homo sapiens OX=9606 GN=TBCC PE=1 SV=2"	"2"	"1"	"1"	"1"	"346"	"39.2"	"5.71"	"246.76"	""	"1"	""	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf07986, Pf16752"	"6903"	"ENSG00000124659"	"TBCC"	"hsa:6903; Q15814; Q53Y43; Q5T787"	"Post-chaperonin tubulin folding pathway"	""	"1"	"0"	"71.8"	"98.7"	"272.4"	"80.8"	"88.0"	"75.3"	"309.2"	"49.5"	"76.9"	"63.3"	"74.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P16885"	"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 OS=Homo sapiens OX=9606 GN=PLCG2 PE=1 SV=4"	"1"	"1"	"1"	"1"	"1265"	"147.8"	"6.64"	"246.75"	""	"1"	""	"cell-cell signaling;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00017, Pf00018, Pf00168, Pf00387, Pf00388"	"5336"	"ENSG00000197943"	"PLCG2"	"D3DUL3; hsa:5336; P16885; Q3ZTS2; Q59H45; Q969T5"	"Generation of second messenger molecules; Role of phospholipids in phagocytosis; FCERI mediated MAPK activation; FCERI mediated Ca+2 mobilization; FCGR3A-mediated IL10 synthesis; Potential therapeutics for SARS; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; CLEC7A (Dectin-1) signaling; Toll Like Receptor 4 (TLR4) Cascade; GPVI-mediated activation cascade; DAP12 signaling; Synthesis of IP3 and IP4 in the cytosol; Signaling by CSF1 (M-CSF) in myeloid cells; Erythropoietin activates Phospholipase C gamma (PLCG); Dectin-2 family"	"Leptin signaling pathway; Glioblastoma signaling pathways; B cell receptor signaling pathway; Corticotropin-releasing hormone signaling pathway; Myometrial relaxation and contraction pathways; Microglia pathogen phagocytosis pathway; GPR40 pathway; Ras signaling; Non-small cell lung cancer; Non-genomic actions of 1,25 dihydroxyvitamin D3; Resistin as a regulator of inflammation; EGFR tyrosine kinase inhibitor resistance; GDNF signaling; 2q13 copy number variation syndrome; ErbB signaling pathway"	"30"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"P43007"	"Neutral amino acid transporter A OS=Homo sapiens OX=9606 GN=SLC1A4 PE=1 SV=1"	"2"	"1"	"2"	"1"	"532"	"55.7"	"6.25"	"246.18"	""	"1"	""	"cell-cell signaling;transport;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"transporter activity"	"Pf00375"	"6509"	"ENSG00000115902"	"SLC1A4"	"B7Z3C0; D6W5F0; hsa:6509; P43007"	"Amino acid transport across the plasma membrane"	"Neuroinflammation and glutamatergic signaling"	"2"	"0"	"12.2"	"15.6"	"88.3"	"11.5"	"11.9"	"11.2"	"93.7"	"13.2"	"26.8"	"30.2"	"104.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HBK9"	"Arsenite methyltransferase OS=Homo sapiens OX=9606 GN=AS3MT PE=1 SV=3"	"3"	"1"	"1"	"1"	"375"	"41.7"	"6.20"	"246.16"	""	"1"	""	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf13847"	"57412"	"ENSG00000214435"	"AS3MT"	"A6NP79; hsa:57412; Q0VDK3; Q0VDK4; Q5PZ02; Q9HBK9"	"Methylation"	"Arsenic metabolism and reactive oxygen species generation"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q13888"	"General transcription factor IIH subunit 2 OS=Homo sapiens OX=9606 GN=GTF2H2 PE=1 SV=1"	"2"	"1"	"1"	"1"	"395"	"44.4"	"6.76"	"246.16"	""	"1"	""	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"nucleus"	"other molecular function"	"Pf04056, Pf07975"	"2966"	"ENSG00000145736; ENSG00000275045; ENSG00000276910"	"GTF2H2"	"hsa:2966; Q13888; Q15570; Q15571; Q9BS41"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Initiation; RNA Polymerase I Transcription Termination; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Dual Incision in GG-NER"	"Eukaryotic transcription initiation; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"33"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q96DR8"	"Mucin-like protein 1 OS=Homo sapiens OX=9606 GN=MUCL1 PE=1 SV=1"	"8"	"1"	"1"	"1"	"90"	"9.0"	"4.64"	"245.29"	""	"1"	""	""	"non-structural extracellular;plasma membrane;other membranes;ER/Golgi"	""	""	"118430"	"ENSG00000172551"	"MUCL1"	"hsa:118430; Q0VG95; Q32ZB5; Q96DR8"	"Dectin-2 family; Termination of O-glycan biosynthesis; Defective GALNT3 causes HFTC; Defective C1GALT1C1 causes TNPS; Defective GALNT12 causes CRCS1"	""	"6"	"0"	"327.4"	"125.8"	"235.2"	"75.3"	"90.8"	"84.1"	"209.9"	"64.5"	"92.3"	"90.3"	"97.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6PJG6"	"BRCA1-associated ATM activator 1 OS=Homo sapiens OX=9606 GN=BRAT1 PE=1 SV=2"	"1"	"1"	"1"	"1"	"821"	"88.1"	"5.27"	"245.27"	""	"1"	""	"cell cycle OR cell proliferation;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	""	"Pf02985"	"221927"	"ENSG00000106009"	"BRAT1"	"A4D200; C9JY24; hsa:221927; Q6PJG6; Q8IW85; Q8IZ43; Q8WVR8; Q96IV9; Q9H7J8; Q9UFA3"	""	""	"0"	"0"	"10.3"	"10.3"	"45.3"	"9.2"	"8.3"	"5.7"	"58.5"	"5.8"	"3.7"	"5.9"	"6.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51649"	"Succinate-semialdehyde dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH5A1 PE=1 SV=2"	"2"	"1"	"1"	"1"	"535"	"57.2"	"8.28"	"245.02"	""	"1"	""	"other metabolic processes;developmental processes"	"mitochondrion"	"other molecular function"	"Pf00171"	"7915"	"ENSG00000112294"	"ALDH5A1"	"B2RD26; G5E949; hsa:7915; P51649; Q546H9; Q8N3W6"	"Degradation of GABA"	"Fragile X syndrome"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75694"	"Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1"	"1"	"1"	"1"	"1"	"1391"	"155.1"	"6.16"	"244.90"	""	"1"	""	"cell-cell signaling;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;nucleus"	"other molecular function"	"Pf03177, Pf08801"	"9631"	"ENSG00000113569"	"NUP155"	"hsa:9631; O75694; Q9UBE9; Q9UFL5"	"HCMV Late Events; HCMV Early Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Postmitotic nuclear pore complex (NPC) reformation"	""	"29"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9C0C9"	"(E3-independent) E2 ubiquitin-conjugating enzyme OS=Homo sapiens OX=9606 GN=UBE2O PE=1 SV=3"	"1"	"1"	"1"	"1"	"1292"	"141.2"	"5.12"	"244.90"	""	"1"	""	"protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00179"	"63893"	"ENSG00000175931"	"UBE2O"	"A6NDU5; hsa:63893; Q69YP4; Q6PIZ2; Q86UA4; Q8N425; Q8TBN1; Q9BSW1; Q9C0C9; Q9H6E6; Q9H7E4; Q9H9B2"	"Antigen processing: Ubiquitination & Proteasome degradation"	""	"1"	"0"	"137.8"	"168.8"	"485.2"	"151.6"	"150.9"	"139.0"	"581.5"	"92.1"	"116.4"	"103.5"	"103.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P15291"	"Beta-1,4-galactosyltransferase 1 OS=Homo sapiens OX=9606 GN=B4GALT1 PE=1 SV=5"	"2"	"1"	"1"	"1"	"398"	"43.9"	"8.65"	"244.40"	""	"1"	""	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02709, Pf13733"	"2683"	"ENSG00000086062"	"B4GALT1"	"B2R710; D3DRL2; hsa:2683; P15291; Q12909; Q12910; Q12911; Q14456; Q14509; Q14523"	"Neutrophil degranulation; Pre-NOTCH Processing in Golgi; N-Glycan antennae elongation; Keratan sulfate biosynthesis; Interaction With Cumulus Cells And The Zona Pellucida; Defective B4GALT1 causes B4GALT1-CDG (CDG-2d); Lactose synthesis; Defective B4GALT1 causes CDG-2d"	"Metabolism of sphingolipids in ER and Golgi apparatus; N-glycan biosynthesis; Synthesis of ceramides and 1-deoxyceramides"	"11"	"0"	"15.7"	"18.8"	"62.8"	"16.6"	"13.0"	"7.3"	"41.4"	"5.3"	"6.8"	"4.1"	"0.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"O43896"	"Kinesin-like protein KIF1C OS=Homo sapiens OX=9606 GN=KIF1C PE=1 SV=3"	"1"	"1"	"1"	"1"	"1103"	"122.9"	"6.90"	"244.00"	""	"1"	""	"transport;other biological processes"	"cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225, Pf00498, Pf16183"	"10749"	"ENSG00000129250"	"KIF1C"	"D3DTL6; hsa:10749; O43896; O75186; Q5U618"	"COPI-dependent Golgi-to-ER retrograde traffic; Kinesins"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75592"	"E3 ubiquitin-protein ligase MYCBP2 OS=Homo sapiens OX=9606 GN=MYCBP2 PE=1 SV=4"	"0"	"1"	"1"	"1"	"4678"	"513.3"	"7.02"	"243.89"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00415, Pf03256, Pf08005, Pf08239, Pf13540, Pf13639"	"23077"	"ENSG00000005810"	"MYCBP2"	"A6NJC6; hsa:23077; O75592; Q5JSX8; Q5VZN6; Q6PIB6; Q9UQ11; Q9Y6E4"	""	"3q29 copy number variation syndrome"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q99698"	"Lysosomal-trafficking regulator OS=Homo sapiens OX=9606 GN=LYST PE=1 SV=3"	"0"	"1"	"1"	"1"	"3801"	"428.9"	"6.61"	"242.97"	""	"1"	""	"cell organization and biogenesis;stress response;transport;other biological processes"	"other membranes;cytosol;cytoskeleton"	"other molecular function"	"Pf00400, Pf02138, Pf14844"	"1130"	"ENSG00000143669"	"LYST"	"hsa:1130; O43274; Q5T2U9; Q96TD7; Q96TD8; Q99698; Q99709; Q9H133"	""	""	"0"	"0"	"165.7"	"169.1"	"505.8"	"125.3"	"96.4"	"91.0"	"404.8"	"58.0"	"83.8"	"59.2"	"71.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P1Z9"	"Coiled-coil domain-containing protein 180 OS=Homo sapiens OX=9606 GN=CCDC180 PE=2 SV=3"	"0"	"1"	"1"	"1"	"1701"	"197.2"	"6.04"	"242.11"	""	"1"	""	""	""	""	"Pf14643, Pf14644"	"100499483"	""	"CCDC180"	"hsa:100499483; Q2KHR6; Q5VV25; Q68DP5; Q69YV9; Q6AHY0; Q9P1Z9"	""	""	"0"	"0"	"226.2"	"301.8"	"767.2"	"207.7"	"193.0"	"181.5"	"611.3"	"64.2"	"94.4"	"78.4"	"73.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2D4"	"Exocyst complex component 6B OS=Homo sapiens OX=9606 GN=EXOC6B PE=1 SV=3"	"1"	"1"	"1"	"1"	"811"	"94.1"	"6.46"	"240.55"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;transport"	"other cell component"	""	"Pf04091"	"23233"	"ENSG00000144036"	"EXOC6B"	"B8ZZY3; hsa:23233; Q9Y2D4"	""	"Ciliary landscape"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NXC5"	"GATOR complex protein MIOS OS=Homo sapiens OX=9606 GN=MIOS PE=1 SV=2"	"1"	"1"	"1"	"1"	"875"	"98.5"	"6.73"	"240.53"	""	"1"	""	"stress response;other biological processes"	"other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	""	"Pf17034"	"54468"	"ENSG00000164654"	"MIOS"	"B2RTV6; hsa:54468; O75216; Q7L551; Q9H092; Q9NXC5"	"Amino acids regulate mTORC1"	""	"1"	"0"	"17.2"	"15.0"	"40.8"	"13.6"	"12.7"	"12.0"	"46.2"	"7.3"	"7.2"	"6.8"	"6.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30260"	"Cell division cycle protein 27 homolog OS=Homo sapiens OX=9606 GN=CDC27 PE=1 SV=2"	"1"	"1"	"1"	"1"	"824"	"91.8"	"7.02"	"240.00"	""	"1"	""	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00515, Pf12895"	"996"	"ENSG00000004897"	"CDC27"	"G3V1C4; hsa:996; P30260; Q16349; Q96F35"	"Senescence-Associated Secretory Phenotype (SASP); Antigen processing: Ubiquitination & Proteasome degradation; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Separation of Sister Chromatids; CDK-mediated phosphorylation and removal of Cdc6; Autodegradation of Cdh1 by Cdh1:APC/C; Assembly of the pre-replicative complex; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of Cyclin B; Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase; Regulation of APC/C activators between G1/S and early anaphase; Phosphorylation of the APC/C; APC-Cdc20 mediated degradation of Nek2A; Transcriptional Regulation by VENTX; Aberrant regulation of mitotic exit in cancer due to RB1 defects"	"Cell cycle; 2q21.1 copy number variation syndrome"	"20"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q10469"	"Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT2 PE=1 SV=1"	"4"	"1"	"1"	"1"	"447"	"51.5"	"8.76"	"239.97"	""	"1"	""	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf05060"	"4247"	"ENSG00000168282"	"MGAT2"	"B3KPC5; B3KQM0; hsa:4247; Q10469"	"Reactions specific to the complex N-glycan synthesis pathway; Maturation of spike protein; Defective MGAT2 causes CDG-2a"	"N-glycan biosynthesis"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9P2P6"	"StAR-related lipid transfer protein 9 OS=Homo sapiens OX=9606 GN=STARD9 PE=1 SV=3"	"0"	"1"	"1"	"1"	"4700"	"516.0"	"6.32"	"239.53"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225, Pf00498, Pf01852"	"57519"	"ENSG00000159433"	"STARD9"	"hsa:57519; Q68DG2; Q6AI01; Q6ZWK0; Q9P2P6; Q9UF70"	""	""	"0"	"0"	"75.5"	"85.8"	"190.2"	"72.6"	"66.2"	"53.3"	"253.2"	"49.3"	"70.7"	"52.7"	"59.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IUH3"	"RNA-binding protein 45 OS=Homo sapiens OX=9606 GN=RBM45 PE=1 SV=1"	"1"	"1"	"1"	"1"	"476"	"53.5"	"7.17"	"239.00"	""	"1"	""	"developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"129831"	"ENSG00000155636"	"RBM45"	"hsa:129831; Q6NYL0; Q8IUH3; Q8NFC9"	""	""	"0"	"0"	"16.7"	"19.4"	"51.7"	"16.5"	"16.0"	"14.2"	"63.2"	"15.6"	"13.1"	"12.9"	"13.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P78330"	"Phosphoserine phosphatase OS=Homo sapiens OX=9606 GN=PSPH PE=1 SV=2"	"4"	"1"	"1"	"1"	"225"	"25.0"	"5.69"	"238.64"	""	"1"	""	"other metabolic processes;developmental processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00702"	"5723"	"ENSG00000146733"	"PSPH"	"B2RCR5; hsa:5723; P78330; Q7Z3S5"	"Serine biosynthesis"	"Trans-sulfuration, one-carbon metabolism and related pathways; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Neuroinflammation and glutamatergic signaling; Amino acid metabolism in triple-negative breast cancer cells"	"6"	"0"	"19.7"	"9.1"	"46.3"	"7.0"	"2.4"	"4.3"	"64.8"	"4.0"	"2.4"	"0.0"	"0.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q6ZSZ5"	"Rho guanine nucleotide exchange factor 18 OS=Homo sapiens OX=9606 GN=ARHGEF18 PE=1 SV=4"	"0"	"1"	"1"	"1"	"1361"	"151.5"	"6.33"	"237.56"	""	"1"	""	"cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00621, Pf17838"	"23370"	"ENSG00000104880"	"ARHGEF18"	"A8MV62; B5ME81; hsa:23370; I3L1I5; O60274; Q6DD92; Q6ZSZ5"	"RHOA GTPase cycle; RAC1 GTPase cycle; NRAGE signals death through JNK; G alpha (12/13) signalling events; TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"	""	"5"	"0"	"16.9"	"20.2"	"33.4"	"18.2"	"17.6"	"12.4"	"51.1"	"24.9"	"33.8"	"26.2"	"28.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UNW1"	"Multiple inositol polyphosphate phosphatase 1 OS=Homo sapiens OX=9606 GN=MINPP1 PE=1 SV=1"	"2"	"1"	"1"	"1"	"487"	"55.0"	"7.81"	"237.36"	""	"1"	""	"other metabolic processes;other biological processes"	"ER/Golgi"	"other molecular function"	"Pf00328"	"9562"	"ENSG00000107789"	"MINPP1"	"F5H683; hsa:9562; O95172; O95286; Q59EJ2; Q9UGA3; Q9UNW1"	"Synthesis of IPs in the ER lumen"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P38935"	"DNA-binding protein SMUBP-2 OS=Homo sapiens OX=9606 GN=IGHMBP2 PE=1 SV=3"	"1"	"1"	"1"	"1"	"993"	"109.1"	"8.97"	"236.79"	""	"1"	""	"cell organization and biogenesis;RNA metabolism OR transcription"	"nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf01424, Pf01428, Pf13086, Pf13087"	"3508"	"ENSG00000132740"	"IGHMBP2"	"A0PJD2; hsa:3508; P38935; Q00443; Q14177"	""	""	"0"	"0"	"15.8"	"14.8"	"67.3"	"15.1"	"10.1"	"8.7"	"78.9"	"19.4"	"36.1"	"30.2"	"50.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5QP82"	"DDB1- and CUL4-associated factor 10 OS=Homo sapiens OX=9606 GN=DCAF10 PE=1 SV=1"	"1"	"1"	"1"	"1"	"559"	"60.5"	"7.50"	"236.68"	""	"1"	""	"protein metabolism;other metabolic processes"	"nucleus;other cell component"	""	"Pf00400"	"79269"	"ENSG00000122741"	"DCAF10"	"A4VCJ5; hsa:79269; Q32NE2; Q5QP82; Q8N2Q5; Q96ET5; Q9BTQ5; Q9H5P6"	"Neddylation"	""	"1"	"0"	"16.6"	"19.2"	"64.2"	"20.3"	"20.4"	"18.1"	"70.5"	"7.5"	"20.2"	"12.8"	"8.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96RS6"	"NudC domain-containing protein 1 OS=Homo sapiens OX=9606 GN=NUDCD1 PE=1 SV=2"	"1"	"1"	"1"	"1"	"583"	"66.7"	"5.11"	"236.58"	""	"1"	""	"other biological processes"	"cytosol;nucleus"	""	"Pf04969"	"84955"	"ENSG00000120526"	"NUDCD1"	"B4DVX6; hsa:84955; Q4G130; Q8NDQ5; Q8NG18; Q96RS6; Q96SI4; Q9BVR5"	""	""	"0"	"0"	"36.5"	"39.5"	"207.0"	"42.9"	"33.9"	"31.0"	"215.4"	"16.5"	"22.6"	"19.2"	"27.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86YB8"	"ERO1-like protein beta OS=Homo sapiens OX=9606 GN=ERO1B PE=1 SV=2"	"2"	"1"	"1"	"1"	"467"	"53.5"	"7.99"	"235.41"	""	"1"	""	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf04137"	"56605"	"ENSG00000086619"	"ERO1B"	"B4DF57; hsa:56605; Q5T1H4; Q86YB8; Q8IZ11; Q9NR62"	"Insulin processing"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43660"	"Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1"	"2"	"1"	"1"	"1"	"514"	"57.2"	"9.17"	"235.34"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;nucleus;other cell component"	""	"Pf00400"	"5356"	"ENSG00000171566"	"PLRG1"	"B3KMK4; hsa:5356; O43660; Q3KQY5; Q8WUD8"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"205.3"	"200.5"	"935.9"	"214.0"	"156.9"	"153.0"	"656.2"	"37.1"	"64.1"	"53.9"	"53.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96CS2"	"HAUS augmin-like complex subunit 1 OS=Homo sapiens OX=9606 GN=HAUS1 PE=1 SV=1"	"6"	"1"	"1"	"1"	"278"	"31.8"	"5.53"	"235.10"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton"	""	""	"115106"	"ENSG00000152240"	"HAUS1"	"B2RDM7; hsa:115106; Q8N837; Q96CS2"	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	""	"7"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2K5"	"R3H domain-containing protein 2 OS=Homo sapiens OX=9606 GN=R3HDM2 PE=1 SV=3"	"1"	"1"	"1"	"1"	"976"	"106.9"	"8.85"	"235.04"	""	"1"	""	""	"nucleus"	""	"Pf01424"	"22864"	"ENSG00000179912"	"R3HDM2"	"B7ZL65; hsa:22864; Q2M1T9; Q3ZCT5; Q9Y2K5"	""	""	"0"	"0"	"62.0"	"65.0"	"281.9"	"74.5"	"37.9"	"32.4"	"145.5"	"15.3"	"23.2"	"27.3"	"31.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q08AD1"	"Calmodulin-regulated spectrin-associated protein 2 OS=Homo sapiens OX=9606 GN=CAMSAP2 PE=1 SV=3"	"0"	"1"	"1"	"1"	"1489"	"168.0"	"6.80"	"234.93"	""	"1"	""	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;ER/Golgi"	"cytoskeletal activity;other molecular function"	"Pf08683, Pf11971, Pf17095"	"23271"	"ENSG00000118200"	"CAMSAP2"	"B1APG6; hsa:23271; Q08AD1; Q08AD2; Q6PGN8; Q96FB3; Q9UG20; Q9UPS4"	""	""	"0"	"0"	"19.6"	"21.0"	"75.0"	"24.1"	"11.5"	"14.6"	"84.8"	"10.9"	"15.2"	"14.3"	"10.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15695"	"Putative U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1 OS=Homo sapiens OX=9606 GN=ZRSR2P1 PE=5 SV=2"	"1"	"1"	"1"	"1"	"479"	"57.6"	"9.36"	"234.78"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00642"	""	""	"ZRSR2P1"	"B2R901; Q13570; Q15695; Q2M3R8"	""	""	"0"	"0"	"56.1"	"49.7"	"88.2"	"57.7"	"43.9"	"45.1"	"91.5"	"24.6"	"38.4"	"34.7"	"30.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96M96"	"FYVE, RhoGEF and PH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=FGD4 PE=1 SV=2"	"1"	"1"	"1"	"1"	"766"	"86.6"	"6.13"	"234.11"	""	"1"	""	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00169, Pf00621, Pf01363"	"121512"	"ENSG00000139132"	"FGD4"	"hsa:121512; Q6ULS2; Q8TCP6; Q96M96"	"CDC42 GTPase cycle; NRAGE signals death through JNK; G alpha (12/13) signalling events"	"Glucocorticoid receptor pathway; Nuclear receptors meta-pathway; Intracellular trafficking proteins involved in CMT neuropathy"	"6"	"0"	"35.4"	"55.5"	"312.1"	"50.5"	"39.6"	"31.0"	"292.2"	"12.0"	"30.0"	"18.9"	"20.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P0C7P0"	"CDGSH iron-sulfur domain-containing protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=CISD3 PE=1 SV=1"	"5"	"1"	"1"	"1"	"127"	"14.2"	"10.55"	"234.08"	""	"1"	""	"protein metabolism;other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf09360"	"284106"	"ENSG00000274768; ENSG00000277972"	"CISD3"	"hsa:284106; P0C7P0"	""	"17q12 copy number variation syndrome"	"1"	"0"	"12.8"	"15.3"	"60.1"	"13.9"	"9.8"	"8.8"	"57.4"	"4.6"	"5.3"	"6.0"	"5.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52758"	"2-iminobutanoate/2-iminopropanoate deaminase OS=Homo sapiens OX=9606 GN=RIDA PE=1 SV=1"	"4"	"1"	"1"	"1"	"137"	"14.5"	"8.68"	"233.85"	""	"1"	""	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01042"	"10247"	"ENSG00000132541"	"RIDA"	"hsa:10247; P52758; Q6FHU9; Q6IBG0"	"Threonine catabolism"	""	"1"	"0"	"35.3"	"32.8"	"127.0"	"28.9"	"20.9"	"19.3"	"142.0"	"14.6"	"21.4"	"15.9"	"12.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6ZMI0"	"Protein phosphatase 1 regulatory subunit 21 OS=Homo sapiens OX=9606 GN=PPP1R21 PE=1 SV=1"	"1"	"1"	"1"	"1"	"780"	"88.3"	"6.84"	"233.77"	""	"1"	""	""	"other cytoplasmic organelle"	""	"Pf10205, Pf10212"	"129285"	"ENSG00000162869"	"PPP1R21"	"B7ZKY5; B7ZKY7; E1B6W7; hsa:129285; Q2TA78; Q6ZMI0; Q6ZMI6; Q8IW83; Q8J029; Q96ES8"	""	""	"0"	"0"	"10.0"	"12.6"	"31.6"	"7.4"	"8.6"	"5.8"	"33.1"	"6.7"	"4.7"	"2.2"	"2.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14976"	"Cyclin-G-associated kinase OS=Homo sapiens OX=9606 GN=GAK PE=1 SV=2"	"1"	"1"	"1"	"1"	"1311"	"143.1"	"5.73"	"233.67"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;ER/Golgi;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf10409"	"2580"	"ENSG00000178950"	"GAK"	"hsa:2580; O14976; Q5U4P5; Q9BVY6"	"Golgi Associated Vesicle Biogenesis; Clathrin-mediated endocytosis"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q659A1"	"Little elongation complex subunit 2 OS=Homo sapiens OX=9606 GN=ICE2 PE=1 SV=2"	"1"	"1"	"1"	"1"	"982"	"109.9"	"7.09"	"233.20"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf10505"	"79664"	"ENSG00000128915"	"ICE2"	"B2RU08; hsa:79664; Q05CT1; Q3B7W6; Q63HP4; Q658Q0; Q659A1; Q68CN8; Q6IPW7; Q6UX23; Q71H65; Q96CY5; Q9HAA2"	"RNA polymerase II transcribes snRNA genes"	""	"1"	"0"	"372.5"	"470.2"	"1069.7"	"330.6"	"300.4"	"270.6"	"885.8"	"131.2"	"177.9"	"112.8"	"118.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BYC9"	"39S ribosomal protein L20, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL20 PE=1 SV=1"	"7"	"1"	"1"	"1"	"149"	"17.4"	"10.86"	"233.20"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00453"	"55052"	"ENSG00000242485"	"MRPL20"	"B2RE41; B7Z746; hsa:55052; Q9BYC9"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"1p36 copy number variation syndrome"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95521"	"PRAME family member 1 OS=Homo sapiens OX=9606 GN=PRAMEF1 PE=2 SV=3"	"1"	"1"	"1"	"1"	"474"	"55.1"	"8.54"	"232.87"	""	"1"	""	"other biological processes"	"other cell component"	""	""	"65121"	"ENSG00000116721"	"PRAMEF1"	"hsa:65121; O95521; Q9UQP2"	""	""	"0"	"0"	"38.7"	"17.6"	"61.7"	"14.6"	"11.2"	"10.2"	"48.9"	"8.0"	"5.2"	"7.6"	"5.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TBB5"	"Kelch domain-containing protein 4 OS=Homo sapiens OX=9606 GN=KLHDC4 PE=1 SV=1"	"2"	"1"	"1"	"1"	"520"	"57.9"	"5.72"	"232.78"	""	"1"	""	""	""	""	"Pf07646, Pf13418, Pf13854, Pf13964"	"54758"	"ENSG00000104731"	"KLHDC4"	"D3DUN3; D3DUN4; D3DUN5; hsa:54758; Q8TBB5; Q96F29; Q9BVN3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15439"	"Multidrug resistance-associated protein 4 OS=Homo sapiens OX=9606 GN=ABCC4 PE=1 SV=3"	"1"	"1"	"1"	"1"	"1325"	"149.4"	"8.19"	"232.74"	""	"1"	""	"cell-cell signaling;cell organization and biogenesis;other metabolic processes;transport"	"plasma membrane;other membranes;ER/Golgi;nucleus"	"transporter activity;other molecular function"	"Pf00005, Pf00664"	"10257"	"ENSG00000125257"	"ABCC4"	"A9Z1Z7; B7Z3Q7; hsa:10257; O15439; Q8IVZ4; Q8IZN6; Q8NEW8; Q9Y6J2"	"ABC-family proteins mediated transport; Paracetamol ADME; Platelet degranulation ; Azathioprine ADME"	"Fluoropyrimidine activity; Androgen receptor network in prostate cancer; Drug induction of bile acid pathway; Ectoderm differentiation; Pregnane X receptor pathway; Nuclear receptors meta-pathway; NRF2 pathway; Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling; TYROBP causal network in microglia; Aspirin and miRNAs; Proximal tubule transport; FOXA2 pathway; Prostaglandin synthesis and regulation"	"17"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"P08574"	"Cytochrome c1, heme protein, mitochondrial OS=Homo sapiens OX=9606 GN=CYC1 PE=1 SV=3"	"2"	"1"	"1"	"1"	"325"	"35.4"	"9.00"	"232.65"	""	"1"	""	"other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf02167"	"1537"	"ENSG00000179091"	"CYC1"	"hsa:1537; P08574; Q5U062; Q6FHS7"	"Respiratory electron transport; Mitochondrial protein import"	"Nonalcoholic fatty liver disease; Mitochondrial complex III assembly"	"4"	"0"	"85.4"	"82.9"	"369.3"	"83.7"	"78.4"	"54.1"	"383.0"	"38.3"	"50.8"	"46.7"	"39.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P4I2"	"WD repeat-containing protein 73 OS=Homo sapiens OX=9606 GN=WDR73 PE=1 SV=1"	"2"	"1"	"1"	"1"	"378"	"41.7"	"5.78"	"231.99"	""	"1"	""	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton"	""	""	"84942"	"ENSG00000177082"	"WDR73"	"hsa:84942; Q6P4I2; Q96JZ1; Q9P0B7"	""	"Nephrotic syndrome"	"1"	"0"	"59.0"	"67.9"	"201.4"	"70.5"	"66.1"	"62.7"	"214.5"	"47.2"	"56.5"	"49.7"	"67.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12996"	"Cleavage stimulation factor subunit 3 OS=Homo sapiens OX=9606 GN=CSTF3 PE=1 SV=1"	"2"	"1"	"1"	"1"	"717"	"82.9"	"8.12"	"231.74"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf05843"	"1479"	"ENSG00000176102"	"CSTF3"	"A8K471; D3DR04; E9PB40; hsa:1479; Q12996; Q32P22; Q96FQ8; Q96QD6; Q96QK4"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"mRNA processing"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9C0D5"	"Protein TANC1 OS=Homo sapiens OX=9606 GN=TANC1 PE=1 SV=3"	"0"	"1"	"1"	"1"	"1861"	"202.1"	"8.32"	"231.48"	""	"1"	""	"cell organization and biogenesis;other biological processes"	"other cell component"	""	"Pf00023, Pf12796"	"85461"	"ENSG00000115183"	"TANC1"	"C9JD88; hsa:85461; Q49AI8; Q9C0D5"	""	""	"0"	"0"	"10.8"	"7.8"	"32.7"	"16.2"	"9.3"	"5.8"	"40.0"	"5.5"	"13.1"	"16.0"	"16.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""