"Checked"	"Master"	"Accession"	"Description"	"Coverage [%]"	"# Peptides"	"# PSMs"	"# Unique Peptides"	"# AAs"	"MW [kDa]"	"calc. pI"	"Score MS Amanda 2.0: MS Amanda 2.0"	"Score Sequest HT: Sequest HT"	"# Peptides (by Search Engine): MS Amanda 2.0"	"# Peptides (by Search Engine): Sequest HT"	"Biological Process"	"Cellular Component"	"Molecular Function"	"Pfam IDs"	"Entrez Gene ID"	"Ensembl Gene ID"	"Gene Symbol"	"Gene ID"	"WikiPathways"	"Reactome Pathways"	"# Protein Pathway Groups"	"# Razor Peptides"	"Abundances (Grouped): 126"	"Abundances (Grouped): 127N"	"Abundances (Grouped): 127C"	"Abundances (Grouped): 128N"	"Abundances (Grouped): 128C"	"Abundances (Grouped): 129N"	"Abundances (Grouped): 129C"	"Abundances (Grouped): 130N"	"Abundances (Grouped): 130C"	"Abundances (Grouped): 131N"	"Abundances (Grouped): 131C"	"Abundances (Grouped) CV [%]: 126"	"Abundances (Grouped) CV [%]: 127N"	"Abundances (Grouped) CV [%]: 127C"	"Abundances (Grouped) CV [%]: 128N"	"Abundances (Grouped) CV [%]: 128C"	"Abundances (Grouped) CV [%]: 129N"	"Abundances (Grouped) CV [%]: 129C"	"Abundances (Grouped) CV [%]: 130N"	"Abundances (Grouped) CV [%]: 130C"	"Abundances (Grouped) CV [%]: 131N"	"Abundances (Grouped) CV [%]: 131C"	"Found in Sample: F31: 126, Sample"	"Found in Sample: F31: 127N, Sample"	"Found in Sample: F31: 127C, Sample"	"Found in Sample: F31: 128N, Sample"	"Found in Sample: F31: 128C, Sample"	"Found in Sample: F31: 129N, Sample"	"Found in Sample: F31: 129C, Sample"	"Found in Sample: F31: 130N, Sample"	"Found in Sample: F31: 130C, Sample"	"Found in Sample: F31: 131N, Sample"	"Found in Sample: F31: 131C, Sample"	"# Protein Groups"	"Modifications"
"False"	"IsMasterProtein"	"P54577"	"Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4"	"80"	"51"	"174"	"51"	"528"	"59.1"	"7.05"	"26989.63"	"309.76"	"40"	"45"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00579, Pf01588"	"8565"	"ENSG00000134684"	"YARS1"	"B3KWK4; D3DPQ4; hsa:8565; O43276; P54577; Q53EN1"	"Nephrotic syndrome"	"Cytosolic tRNA aminoacylation"	"2"	"0"	"1480.4"	"2857.1"	"2989.7"	"1496.2"	"3277.7"	"2024.9"	"4508.0"	"5758.9"	"19041.7"	"39112.5"	"53929.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23284"	"Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2"	"65"	"22"	"136"	"22"	"216"	"23.7"	"9.41"	"19944.84"	"267.86"	"17"	"22"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00160"	"5479"	"ENSG00000166794"	"PPIB"	"A8K534; hsa:5479; P23284; Q6IBH5; Q9BVK5"	"Prolactin signaling pathway; Type I collagen synthesis in the context of osteogenesis imperfecta"	"Collagen biosynthesis and modifying enzymes; SARS-CoV-1 activates/modulates innate immune responses"	"4"	"0"	"975.7"	"1944.3"	"2089.5"	"920.6"	"2192.4"	"1212.9"	"4154.9"	"6745.3"	"12372.3"	"21700.1"	"38157.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11142"	"Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1"	"56"	"37"	"126"	"29"	"646"	"70.9"	"5.52"	"22518.70"	"226.41"	"33"	"36"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00012"	"3312"	"ENSG00000109971"	"HSPA8"	"hsa:3312; P11142; Q9H3R6"	"Parkin-ubiquitin proteasomal system pathway; MAPK signaling pathway; Exercise-induced circadian regulation; Measles virus infection; Opioid receptor pathways; Extrafollicular and follicular B cell activation by SARS-CoV-2; 1p36 copy number variation syndrome"	"AUF1 (hnRNP D0) binds and destabilizes mRNA; Neutrophil degranulation; Golgi Associated Vesicle Biogenesis; Clathrin-mediated endocytosis; Late endosomal microautophagy; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Regulation of HSF1-mediated heat shock response; Lysosome Vesicle Biogenesis; mRNA Splicing - Major Pathway; CHL1 interactions; Interleukin-4 and Interleukin-13 signaling; GABA synthesis, release, reuptake and degradation; Lipophagy; Chaperone Mediated Autophagy; Protein methylation; Attenuation phase"	"24"	"10"	"5179.5"	"14016.0"	"14604.2"	"4931.5"	"11949.5"	"6120.8"	"10408.5"	"8625.7"	"11526.9"	"13193.6"	"19838.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09874"	"Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4"	"46"	"47"	"140"	"47"	"1014"	"113.0"	"8.88"	"25721.27"	"213.02"	"45"	"40"	"cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00533, Pf00644, Pf00645, Pf02877, Pf05406, Pf08063"	"142"	"ENSG00000143799"	"PARP1"	"B1ANJ4; hsa:142; P09874; Q8IUZ9"	"Corticotropin-releasing hormone signaling pathway; Nanoparticle triggered regulated necrosis; Fas ligand pathway and stress induction of heat shock proteins; NAD metabolism, sirtuins and aging; NAD+ metabolism; NAD+ biosynthetic pathways; Breast cancer pathway; Acute viral myocarditis; Joubert syndrome; Male infertility; Base excision repair; IL-18 signaling pathway; DNA repair pathways, full network; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Progeria-associated lipodystrophy; Primary ovarian insufficiency; 10q11.21q11.23 copy number variation syndrome; A network map of Macrophage-stimulating protein (MSP) signaling"	"SUMOylation of DNA damage response and repair proteins; Downregulation of SMAD2/3:SMAD4 transcriptional activity; HDR through MMEJ (alt-NHEJ); Formation of Incision Complex in GG-NER; DNA Damage Recognition in GG-NER; vRNA Synthesis; POLB-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER"	"26"	"0"	"2912.3"	"5405.7"	"6790.1"	"2623.9"	"5332.6"	"3358.5"	"13635.0"	"10275.2"	"14652.7"	"22235.4"	"36321.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04406"	"Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3"	"69"	"24"	"100"	"24"	"335"	"36.0"	"8.46"	"14977.21"	"209.87"	"17"	"22"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00044, Pf02800"	"2597"	"ENSG00000111640"	"GAPDH"	"E7EUT4; hsa:2597; P00354; P04406; Q53X65"	"Cori cycle; Alzheimer's disease and miRNA effects; HIF1A and PPARG regulation of glycolysis; VEGFA-VEGFR2 signaling; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Aerobic glycolysis; 7q11.23 copy number variation syndrome; Glycolysis in senescence; Alzheimer's disease; Sildenafil treatment; Glycolysis and gluconeogenesis; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Glycolysis; Gluconeogenesis"	"15"	"0"	"1963.4"	"3455.9"	"4255.0"	"1735.4"	"3522.8"	"2269.3"	"9640.7"	"7365.5"	"8821.8"	"10277.9"	"15942.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22102"	"Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1"	"47"	"39"	"97"	"39"	"1010"	"107.7"	"6.70"	"13904.93"	"198.15"	"27"	"36"	"other metabolic processes;developmental processes;other biological processes"	"cytosol"	"other molecular function"	"Pf00551, Pf00586, Pf01071, Pf02769, Pf02843, Pf02844"	"2618"	"ENSG00000159131; ENSG00000262473"	"GART"	"A8K945; A8KA32; D3DSF3; D3DSF4; hsa:2618; O14659; P22102; Q52M77"	"Folate metabolism; One-carbon metabolism; Metabolic reprogramming in colon cancer"	"Purine ribonucleoside monophosphate biosynthesis"	"4"	"0"	"855.7"	"2010.8"	"2212.4"	"745.4"	"1921.2"	"1032.1"	"2357.0"	"4548.2"	"8504.4"	"14734.5"	"25163.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13639"	"Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4"	"49"	"41"	"117"	"40"	"858"	"95.3"	"6.83"	"22524.69"	"189.20"	"38"	"34"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00009, Pf00679, Pf03144, Pf03764, Pf14492"	"1938"	"ENSG00000167658"	"EEF2"	"A0A384N6H1; B2RMP5; D6W618; hsa:1938; P13639; Q58J86"	"Translation factors; AMP-activated protein kinase signaling; Brain-derived neurotrophic factor (BDNF) signaling pathway; IL-18 signaling pathway"	"Neutrophil degranulation; Protein methylation; Uptake and function of diphtheria toxin; Peptide chain elongation; Synthesis of diphthamide-EEF2"	"9"	"1"	"3237.2"	"7242.7"	"7196.6"	"3082.6"	"6595.0"	"3697.7"	"4977.5"	"4111.8"	"5796.4"	"7797.5"	"12696.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08238"	"Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4"	"47"	"35"	"102"	"19"	"724"	"83.2"	"5.03"	"17644.66"	"180.78"	"30"	"29"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00183, Pf02518"	"3326"	"ENSG00000096384"	"HSP90AB1"	"B2R5P0; hsa:3326; P08238; Q5T9W7; Q9NQW0; Q9NTK6"	"Nuclear receptors meta-pathway; NRF2 pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway"	"The role of GTSE1 in G2/M progression after G2 checkpoint; Neutrophil degranulation; Regulation of actin dynamics for phagocytic cup formation; Potential therapeutics for SARS; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Aryl hydrocarbon receptor signalling; Estrogen-dependent gene expression; Sema3A PAK dependent Axon repulsion; DDX58/IFIH1-mediated induction of interferon-alpha/beta; The NLRP3 inflammasome; Purinergic signaling in leishmaniasis infection; RHOBTB2 GTPase cycle; Chaperone Mediated Autophagy; HSF1 activation; Attenuation phase; Uptake and function of diphtheria toxin"	"23"	"21"	"2286.0"	"14143.4"	"10229.6"	"1608.8"	"8779.9"	"2730.8"	"3201.9"	"2766.7"	"4044.3"	"5587.0"	"10563.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14618"	"Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4"	"64"	"29"	"90"	"29"	"531"	"57.9"	"7.84"	"17082.53"	"172.63"	"23"	"26"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00224, Pf02887"	"5315"	"ENSG00000067225"	"PKM"	"A6NFK3; B2R5N8; B3KRY0; B4DFX8; B4DUU6; hsa:5315; P14618; P14786; Q53GK4; Q96E76; Q9BWB5; Q9UCV6; Q9UPF2"	"Photodynamic therapy-induced HIF-1 survival signaling; Amino acid metabolism; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Aerobic glycolysis; Glycolysis in senescence; Glucose metabolism in triple-negative breast cancer cells; Glycolysis and gluconeogenesis"	"Neutrophil degranulation"	"9"	"0"	"2703.5"	"8160.4"	"6853.9"	"2629.8"	"6006.2"	"3137.2"	"3755.7"	"3235.6"	"4194.8"	"7095.9"	"13613.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07900"	"Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5"	"43"	"32"	"97"	"17"	"732"	"84.6"	"5.02"	"15245.62"	"171.56"	"27"	"29"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"non-structural extracellular;extracellular matrix;plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00183, Pf02518"	"3320"	"ENSG00000080824"	"HSP90AA1"	"A8K500; B3KPJ9; hsa:3320; P07900; Q2PP14; Q5CAQ6; Q5CAQ7; Q9BVQ5"	"Nucleotide-binding oligomerization domain (NOD) pathway; TNF-alpha signaling pathway; Corticotropin-releasing hormone signaling pathway; Aryl hydrocarbon receptor pathway; Ebstein-Barr virus LMP1 signaling; Aryl hydrocarbon receptor pathway; Constitutive androstane receptor pathway; Pregnane X receptor pathway; Glucocorticoid receptor pathway; Nuclear receptors meta-pathway; NRF2 pathway; VEGFA-VEGFR2 signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Th17 cell differentiation pathway"	"Regulation of actin dynamics for phagocytic cup formation; Potential therapeutics for SARS; The role of GTSE1 in G2/M progression after G2 checkpoint; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Recruitment of NuMA to mitotic centrosomes; Aggrephagy; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Extra-nuclear estrogen signaling; Neutrophil degranulation; vRNP Assembly; Estrogen-dependent gene expression; Regulation of necroptotic cell death; Interleukin-4 and Interleukin-13 signaling; Downregulation of ERBB2 signaling; Signaling by ERBB2 KD Mutants; Signaling by ERBB2 TMD/JMD mutants; Sema3A PAK dependent Axon repulsion; DDX58/IFIH1-mediated induction of interferon-alpha/beta; PIWI-interacting RNA (piRNA) biogenesis; VEGFR2 mediated vascular permeability; RHOBTB2 GTPase cycle; Chaperone Mediated Autophagy; HSF1 activation; Attenuation phase; eNOS activation; Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation; Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; Constitutive Signaling by EGFRvIII; Signaling by ERBB2 ECD mutants; Uptake and function of diphtheria toxin; Constitutive Signaling by Overexpressed ERBB2; Scavenging by Class F Receptors; Drug-mediated inhibition of ERBB2 signaling; Resistance of ERBB2 KD mutants to trastuzumab; Resistance of ERBB2 KD mutants to sapitinib; Resistance of ERBB2 KD mutants to tesevatinib; Resistance of ERBB2 KD mutants to neratinib; Resistance of ERBB2 KD mutants to osimertinib; Resistance of ERBB2 KD mutants to afatinib; Resistance of ERBB2 KD mutants to AEE788; Resistance of ERBB2 KD mutants to lapatinib; Drug resistance in ERBB2 TMD/JMD mutants"	"67"	"0"	"935.2"	"4763.6"	"3969.6"	"898.8"	"3735.2"	"1233.6"	"1147.9"	"885.2"	"1298.3"	"1756.4"	"3218.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07437"	"Tubulin beta chain OS=Homo sapiens OX=9606 GN=TUBB PE=1 SV=2"	"67"	"23"	"84"	"7"	"444"	"49.6"	"4.89"	"13944.03"	"154.84"	"19"	"23"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;other biological processes"	"non-structural extracellular;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00091, Pf03953"	"203068"	"ENSG00000183311; ENSG00000196230; ENSG00000224156; ENSG00000227739; ENSG00000229684; ENSG00000232421; ENSG00000232575; ENSG00000235067"	"TUBB"	"hsa:203068; P05218; P07437; Q8WUC1; Q9CY33"	"Alzheimer's disease and miRNA effects; Pathogenic Escherichia coli infection; Parkin-ubiquitin proteasomal system pathway; Opioid receptor pathways; Alzheimer's disease"	"Potential therapeutics for SARS; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Neutrophil degranulation"	"14"	"18"	"1231.4"	"4413.3"	"3704.6"	"892.2"	"3093.0"	"1303.3"	"1747.1"	"1412.6"	"2048.2"	"2868.6"	"4709.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19338"	"Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3"	"41"	"44"	"106"	"44"	"710"	"76.6"	"4.70"	"18149.57"	"153.83"	"37"	"36"	"developmental processes;other biological processes"	"plasma membrane;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"4691"	"ENSG00000115053"	"NCL"	"hsa:4691; P19338; Q53SK1; Q8NB06; Q9UCF0; Q9UDG1"	"Pathogenic Escherichia coli infection; VEGFA-VEGFR2 signaling"	"Major pathway of rRNA processing in the nucleolus and cytosol"	"3"	"0"	"6756.3"	"10246.9"	"11177.4"	"5467.5"	"10780.2"	"6990.6"	"16155.8"	"12567.9"	"15898.3"	"17258.7"	"24937.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7KZF4"	"Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1"	"39"	"31"	"75"	"31"	"910"	"101.9"	"7.17"	"12877.92"	"153.45"	"25"	"31"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00565, Pf00567"	"27044"	"ENSG00000197157"	"SND1"	"hsa:27044; Q13122; Q7KZF4; Q96AG0"	"VEGFA-VEGFR2 signaling"	"Signaling by BRAF and RAF1 fusions"	"2"	"0"	"1268.8"	"2307.0"	"2516.1"	"1092.7"	"2192.0"	"1360.1"	"5317.7"	"4241.7"	"5952.5"	"7443.9"	"11887.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P0DMV9"	"Heat shock 70 kDa protein 1B OS=Homo sapiens OX=9606 GN=HSPA1B PE=1 SV=1"	"50"	"31"	"89"	"25"	"641"	"70.0"	"5.66"	"16609.86"	"150.28"	"27"	"29"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00012"	"3303; 3304"	"ENSG00000204388; ENSG00000212866; ENSG00000224501; ENSG00000231555; ENSG00000232804"	"HSPA1B"	"B4E3B6; hsa:3303; hsa:3304; P08107; P0DMV9; P19790; Q5JQI4; Q5SP17; Q9UQL9; Q9UQM0"	"Apoptosis modulation and signaling; Parkin-ubiquitin proteasomal system pathway; MAPK signaling pathway; Apoptosis modulation by HSP70; VEGFA-VEGFR2 signaling; Measles virus infection; CKAP4 signaling pathway map"	"Regulation of HSF1-mediated heat shock response; Neutrophil degranulation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Attenuation phase"	"12"	"0"	"3253.1"	"7932.8"	"7511.0"	"3066.5"	"7038.8"	"3715.5"	"5727.4"	"4670.6"	"6004.7"	"7097.7"	"10754.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y450"	"HBS1-like protein OS=Homo sapiens OX=9606 GN=HBS1L PE=1 SV=1"	"44"	"25"	"54"	"25"	"684"	"75.4"	"6.61"	"7703.40"	"142.89"	"15"	"25"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03143, Pf03144, Pf08938"	"10767"	"ENSG00000112339"	"HBS1L"	"B7Z365; hsa:10767; Q4VX89; Q4VX90; Q5T7G3; Q8NDW9; Q9UPW3; Q9Y450"	"10q11.21q11.23 copy number variation syndrome"	"mRNA decay by 3' to 5' exoribonuclease"	"2"	"0"	"422.2"	"790.9"	"862.2"	"398.2"	"830.7"	"484.4"	"1035.2"	"1322.2"	"4173.9"	"8433.4"	"13216.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94973"	"AP-2 complex subunit alpha-2 OS=Homo sapiens OX=9606 GN=AP2A2 PE=1 SV=2"	"33"	"28"	"70"	"21"	"939"	"103.9"	"6.96"	"11077.98"	"133.93"	"20"	"27"	"transport"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01602, Pf02296, Pf02883"	"161"	"ENSG00000183020"	"AP2A2"	"hsa:161; O75403; O94973; Q53ET1; Q96SI8"	"Synaptic vesicle pathway; GABA receptor signaling; mBDNF and proBDNF regulation of GABA neurotransmission"	"Neutrophil degranulation; Potential therapeutics for SARS; Recycling pathway of L1; MHC class II antigen presentation; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; LDL clearance; Nef Mediated CD4 Down-regulation; Retrograde neurotrophin signalling; Nef Mediated CD8 Down-regulation; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; VLDLR internalisation and degradation"	"17"	"6"	"522.2"	"1130.2"	"1195.0"	"502.4"	"1245.0"	"679.5"	"1405.1"	"2145.9"	"6062.3"	"11771.8"	"18827.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P68363"	"Tubulin alpha-1B chain OS=Homo sapiens OX=9606 GN=TUBA1B PE=1 SV=1"	"48"	"20"	"68"	"1"	"451"	"50.1"	"5.06"	"10952.51"	"128.31"	"16"	"17"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00091, Pf03953"	"10376"	"ENSG00000123416"	"TUBA1B"	"hsa:10376; P04687; P05209; P68363; Q27I68; Q8WU19"	"Alzheimer's disease and miRNA effects; Pathogenic Escherichia coli infection; Allograft rejection; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"Recycling pathway of L1; COPI-dependent Golgi-to-ER retrograde traffic; MHC class II antigen presentation; Kinesins; HCMV Early Events; RHO GTPases Activate Formins; Intraflagellar transport; Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane; Gap junction assembly; Resolution of Sister Chromatid Cohesion; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Recruitment of NuMA to mitotic centrosomes; Formation of tubulin folding intermediates by CCT/TriC; Post-chaperonin tubulin folding pathway; RHO GTPases activate IQGAPs; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Carboxyterminal post-translational modifications of tubulin; Assembly and cell surface presentation of NMDA receptors; Activation of AMPK downstream of NMDARs; Aggrephagy; EML4 and NUDC in mitotic spindle formation; Sealing of the nuclear envelope (NE) by ESCRT-III; Hedgehog 'off' state; RHOH GTPase cycle"	"35"	"22"	"1757.6"	"8394.2"	"6027.8"	"1143.9"	"4852.0"	"1788.8"	"2765.5"	"2500.1"	"3290.8"	"4828.8"	"8315.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P27816"	"Microtubule-associated protein 4 OS=Homo sapiens OX=9606 GN=MAP4 PE=1 SV=3"	"35"	"35"	"77"	"35"	"1152"	"120.9"	"5.43"	"13802.75"	"125.64"	"29"	"32"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00418"	"4134"	"ENSG00000047849"	"MAP4"	"hsa:4134; P27816; Q13082; Q59FT2; Q68D74; Q6ZUW9; Q86V26; Q96A76; Q96NS9"	"Splicing factor NOVA regulated synaptic proteins; 2q37 copy number variation syndrome"	""	"2"	"0"	"2802.3"	"5403.2"	"5675.7"	"2532.0"	"5604.5"	"3126.4"	"9000.9"	"6204.2"	"8847.3"	"9888.5"	"13677.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P12956"	"X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2"	"42"	"26"	"72"	"26"	"609"	"69.8"	"6.64"	"14221.86"	"124.54"	"22"	"23"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02037, Pf02735, Pf03730, Pf03731"	"2547"	"ENSG00000196419"	"XRCC6"	"B1AHC8; hsa:2547; P12956; Q6FG89; Q9UCQ2; Q9UCQ3"	"Non-homologous end joining; DNA repair pathways, full network; Primary ovarian insufficiency; 10q11.21q11.23 copy number variation syndrome"	"Neutrophil degranulation; Cytosolic sensors of pathogen-associated DNA ; Nonhomologous End-Joining (NHEJ); 2-LTR circle formation; IRF3-mediated induction of type I IFN"	"9"	"0"	"1963.4"	"5153.1"	"4840.5"	"1730.9"	"4322.8"	"2121.7"	"3975.4"	"2888.0"	"4200.7"	"5274.6"	"7851.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P68371"	"Tubulin beta-4B chain OS=Homo sapiens OX=9606 GN=TUBB4B PE=1 SV=1"	"56"	"19"	"66"	"3"	"445"	"49.8"	"4.89"	"10824.05"	"123.27"	"16"	"19"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response"	"non-structural extracellular;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00091, Pf03953"	"10383"	"ENSG00000188229"	"TUBB4B"	"A2BFA2; hsa:10383; P05217; P68371"	"Alzheimer's disease and miRNA effects; Pathogenic Escherichia coli infection; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"Separation of Sister Chromatids; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; RHO GTPases Activate Formins; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; HCMV Early Events; Aggrephagy; EML4 and NUDC in mitotic spindle formation; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Neutrophil degranulation; COPI-dependent Golgi-to-ER retrograde traffic; Intraflagellar transport; Recycling pathway of L1; The role of GTSE1 in G2/M progression after G2 checkpoint; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane; Gap junction assembly; Formation of tubulin folding intermediates by CCT/TriC; Post-chaperonin tubulin folding pathway; RHO GTPases activate IQGAPs; Carboxyterminal post-translational modifications of tubulin; Assembly and cell surface presentation of NMDA receptors; Activation of AMPK downstream of NMDARs; Sealing of the nuclear envelope (NE) by ESCRT-III; Kinesins; Prefoldin mediated transfer of substrate  to CCT/TriC; Hedgehog 'off' state"	"41"	"0"	"76.1"	"412.2"	"329.3"	"45.6"	"234.6"	"74.0"	"130.5"	"112.8"	"164.3"	"239.7"	"438.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQE3"	"Tubulin alpha-1C chain OS=Homo sapiens OX=9606 GN=TUBA1C PE=1 SV=1"	"48"	"20"	"66"	"1"	"449"	"49.9"	"5.10"	"10563.23"	"123.16"	"16"	"17"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00091, Pf03953"	"84790"	"ENSG00000167553"	"TUBA1C"	"hsa:84790; Q9BQE3"	"Alzheimer's disease and miRNA effects; Pathogenic Escherichia coli infection; Parkin-ubiquitin proteasomal system pathway; VEGFA-VEGFR2 signaling; Alzheimer's disease"	"Separation of Sister Chromatids; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; RHO GTPases Activate Formins; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; HCMV Early Events; Aggrephagy; EML4 and NUDC in mitotic spindle formation; Recruitment of NuMA to mitotic centrosomes; COPI-dependent Golgi-to-ER retrograde traffic; Intraflagellar transport; Recycling pathway of L1; The role of GTSE1 in G2/M progression after G2 checkpoint; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane; Gap junction assembly; Formation of tubulin folding intermediates by CCT/TriC; Post-chaperonin tubulin folding pathway; RHO GTPases activate IQGAPs; Carboxyterminal post-translational modifications of tubulin; Assembly and cell surface presentation of NMDA receptors; Activation of AMPK downstream of NMDARs; Sealing of the nuclear envelope (NE) by ESCRT-III; Kinesins; Prefoldin mediated transfer of substrate  to CCT/TriC; Hedgehog 'off' state"	"35"	"0"	"15.7"	"51.5"	"44.9"	"7.1"	"41.5"	"21.1"	"17.1"	"16.2"	"19.6"	"32.9"	"52.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P12532"	"Creatine kinase U-type, mitochondrial OS=Homo sapiens OX=9606 GN=CKMT1A PE=1 SV=1"	"49"	"17"	"64"	"17"	"417"	"47.0"	"8.34"	"10643.69"	"121.44"	"13"	"15"	"other metabolic processes"	"other membranes;mitochondrion"	"kinase activity;other molecular function"	"Pf00217, Pf02807"	"1159; 548596"	"ENSG00000223572; ENSG00000237289"	"CKMT1A; CKMT1B"	"B4DIT8; B7ZA09; hsa:1159; hsa:548596; P12532; Q0VAM3; Q32NF6; Q53FC4"	""	"Creatine metabolism"	"1"	"0"	"992.3"	"1741.5"	"1918.0"	"920.2"	"1888.0"	"992.6"	"6688.5"	"5918.6"	"6915.3"	"7494.6"	"8945.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11021"	"Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2"	"48"	"32"	"74"	"29"	"654"	"72.3"	"5.16"	"14629.29"	"120.28"	"27"	"28"	"protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;nucleus;other cell component"	"translation activity;other molecular function"	"Pf00012"	"3309"	"ENSG00000044574"	"HSPA5"	"B0QZ61; hsa:3309; P11021; Q2EF78; Q9NPF1; Q9UK02"	"Parkin-ubiquitin proteasomal system pathway; Apoptosis-related network due to altered Notch3 in ovarian cancer; Photodynamic therapy-induced unfolded protein response; Prion disease pathway; Unfolded protein response; Orexin receptor pathway"	"Regulation of HSF1-mediated heat shock response; Platelet degranulation ; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; ATF6B (ATF6-beta) activates chaperones; IRE1alpha activates chaperones; PERK regulates gene expression; ATF6 (ATF6-alpha) activates chaperone genes"	"14"	"0"	"2014.8"	"6008.5"	"5690.5"	"1765.3"	"5119.7"	"2305.0"	"3683.2"	"3009.0"	"4224.8"	"5073.5"	"8598.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P00367"	"Glutamate dehydrogenase 1, mitochondrial OS=Homo sapiens OX=9606 GN=GLUD1 PE=1 SV=2"	"47"	"24"	"76"	"24"	"558"	"61.4"	"7.80"	"12777.01"	"118.40"	"20"	"22"	"other metabolic processes;other biological processes"	"mitochondrion;ER/Golgi;other cell component"	"other molecular function"	"Pf00208, Pf02812"	"2746"	"ENSG00000148672"	"GLUD1"	"B3KV55; B4DGN5; hsa:2746; P00367; Q5TBU3"	"VEGFA-VEGFR2 signaling; Amino acid metabolism; Metabolic reprogramming in colon cancer; 22q11.2 copy number variation syndrome; Amino acid metabolism pathway excerpt: histidine catabolism extension"	"Transcriptional activation of mitochondrial biogenesis; Glutamate and glutamine metabolism"	"7"	"0"	"4549.5"	"5477.8"	"5580.3"	"3932.5"	"5678.1"	"4205.7"	"6005.2"	"4414.9"	"5712.8"	"6632.5"	"9016.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P36578"	"60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5"	"51"	"28"	"80"	"27"	"427"	"47.7"	"11.06"	"14717.79"	"117.15"	"27"	"22"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00573, Pf14374"	"6124"	"ENSG00000174444"	"RPL4"	"A8K502; hsa:6124; P36578; P39029; Q4VBR0; Q969Z9"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"1"	"3158.1"	"5652.7"	"5754.3"	"2628.1"	"5577.3"	"3194.1"	"11289.7"	"8873.9"	"10568.6"	"12283.3"	"16921.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22626"	"Heterogeneous nuclear ribonucleoproteins A2/B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2"	"46"	"13"	"51"	"12"	"353"	"37.4"	"8.95"	"6871.35"	"116.53"	"11"	"13"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"3181"	"ENSG00000122566"	"HNRNPA2B1"	"A0A024RA27; A0A024RA61; A8K064; hsa:3181; P22626; P22627; Q9UC98; Q9UDJ2"	"mRNA processing"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"4"	"1"	"2109.2"	"4418.3"	"4175.6"	"1627.0"	"3494.6"	"2039.3"	"3730.9"	"2933.8"	"4060.5"	"4643.9"	"7975.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04264"	"Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6"	"35"	"23"	"63"	"17"	"644"	"66.0"	"8.12"	"10161.07"	"115.84"	"20"	"21"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"bone, tooth or skin structural activity;other molecular function"	"Pf00038, Pf16208, Pf16210"	"3848"	"ENSG00000167768"	"KRT1"	"B2RA01; hsa:3848; P04264; P85925; P86104; Q14720; Q6GSJ0; Q9H298"	"Corticotropin-releasing hormone signaling pathway"	"Formation of the cornified envelope; Neutrophil degranulation"	"4"	"6"	"1287.8"	"4107.2"	"16030.9"	"957.2"	"968.7"	"1134.0"	"1927.4"	"3079.8"	"4574.7"	"4959.6"	"3514.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UQ80"	"Proliferation-associated protein 2G4 OS=Homo sapiens OX=9606 GN=PA2G4 PE=1 SV=3"	"50"	"21"	"65"	"21"	"394"	"43.8"	"6.55"	"11100.22"	"115.19"	"19"	"20"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"non-structural extracellular;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00557"	"5036"	"ENSG00000170515"	"PA2G4"	"hsa:5036; O43846; Q9UM59; Q9UQ80"	""	"Neutrophil degranulation"	"1"	"0"	"1757.7"	"2410.2"	"2714.8"	"1452.0"	"3003.3"	"1702.3"	"5385.2"	"4361.3"	"5218.4"	"6277.1"	"8590.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P99999"	"Cytochrome c OS=Homo sapiens OX=9606 GN=CYCS PE=1 SV=2"	"70"	"14"	"73"	"14"	"105"	"11.7"	"9.57"	"14196.91"	"113.68"	"14"	"12"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"other membranes;cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf00034"	"54205"	"ENSG00000172115"	"CYCS"	"A4D166; B2R4I1; hsa:54205; P00001; P99999; Q6NUR2; Q6NX69; Q96BV4"	"miRNA regulation of DNA damage response; Apoptosis modulation and signaling; Alzheimer's disease and miRNA effects; AGE/RAGE pathway; Parkinson's disease pathway; Nanomaterial induced apoptosis; Apoptosis; Fas ligand pathway and stress induction of heat shock proteins; Apoptosis modulation by HSP70; VEGFA-VEGFR2 signaling; Oxidative damage response; NO/cGMP/PKG mediated neuroprotection; Chromosomal and microsatellite instability in colorectal cancer ; Non-small cell lung cancer; Acute viral myocarditis; Nonalcoholic fatty liver disease; Measles virus infection; Small cell lung cancer; Hepatitis B infection; IL-18 signaling pathway; Pleural mesothelioma; Complement system in neuronal development and plasticity; Alzheimer's disease; DNA damage response"	"Respiratory electron transport; Detoxification of Reactive Oxygen Species; Transcriptional activation of mitochondrial biogenesis; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1; Activation of caspases through apoptosome-mediated cleavage; SMAC (DIABLO) binds to IAPs ; SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes ; Regulation of the apoptosome activity; Release of apoptotic factors from the mitochondria; Pyroptosis"	"36"	"0"	"871.8"	"1397.6"	"1591.2"	"947.6"	"1563.4"	"939.3"	"6746.3"	"6793.0"	"7506.0"	"10674.6"	"17014.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60709"	"Actin, cytoplasmic 1 OS=Homo sapiens OX=9606 GN=ACTB PE=1 SV=1"	"33"	"13"	"57"	"3"	"375"	"41.7"	"5.48"	"10646.30"	"110.26"	"9"	"12"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00022"	"60"	"ENSG00000075624"	"ACTB"	"hsa:60; P02570; P60709; P70514; P99021; Q11211; Q64316; Q75MN2; Q96B34; Q96HG5"	"Arrhythmogenic right ventricular cardiomyopathy; Pathogenic Escherichia coli infection; Common pathways underlying drug addiction; Myometrial relaxation and contraction pathways; Focal adhesion; Fas ligand pathway and stress induction of heat shock proteins; Ebola virus infection in host; Acute viral myocarditis; Thermogenesis; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Overlap between signal transduction pathways contributing to LMNA laminopathies; Pleural mesothelioma; Regulation of actin cytoskeleton; Network map of SARS-CoV-2 signaling pathway"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; UCH proteinases; Clathrin-mediated endocytosis; DNA Damage Recognition in GG-NER; Signaling by BRAF and RAF1 fusions; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; RHOF GTPase cycle; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; Recycling pathway of L1; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; RHO GTPases Activate WASPs and WAVEs; RHO GTPases activate IQGAPs; RHO GTPases Activate Formins; B-WICH complex positively regulates rRNA expression; EPHB-mediated forward signaling; VEGFA-VEGFR2 Pathway; Factors involved in megakaryocyte development and platelet production; EPH-ephrin mediated repulsion of cells; HATs acetylate histones; Interaction between L1 and Ankyrins; Prefoldin mediated transfer of substrate  to CCT/TriC; Signaling by RAF1 mutants; Adherens junctions interactions; Formation of annular gap junctions; Folding of actin by CCT/TriC; Cell-extracellular matrix interactions"	"47"	"15"	"841.2"	"7875.9"	"6153.0"	"395.8"	"4889.7"	"1395.5"	"2287.5"	"1678.7"	"2249.6"	"3000.1"	"5830.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63010"	"AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1"	"24"	"23"	"59"	"14"	"937"	"104.5"	"5.38"	"7128.54"	"108.70"	"18"	"22"	"transport;developmental processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01602, Pf02883, Pf09066"	"163"	"ENSG00000006125"	"AP2B1"	"A6NJP3; hsa:163; P21851; P63010; Q7Z451; Q96J19"	"Synaptic vesicle pathway; GABA receptor signaling; EGF/EGFR signaling pathway; Fragile X syndrome; mBDNF and proBDNF regulation of GABA neurotransmission; Markers of kidney cell lineage; 17q12 copy number variation syndrome"	"Cargo recognition for clathrin-mediated endocytosis; VLDLR internalisation and degradation; WNT5A-dependent internalization of FZD4; MHC class II antigen presentation; Recycling pathway of L1; Retrograde neurotrophin signalling; Potential therapeutics for SARS; EPH-ephrin mediated repulsion of cells; LDL clearance; Nef Mediated CD4 Down-regulation; Nef Mediated CD8 Down-regulation; WNT5A-dependent internalization of FZD2, FZD5 and ROR2"	"20"	"7"	"543.0"	"1259.5"	"1296.5"	"540.2"	"1243.5"	"674.7"	"1465.0"	"2077.6"	"5727.9"	"11047.0"	"17418.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P68104"	"Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1"	"42"	"17"	"53"	"8"	"462"	"50.1"	"9.01"	"7253.98"	"105.88"	"14"	"14"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;translational apparatus;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03143, Pf03144"	"1915"	"ENSG00000156508"	"EEF1A1"	"hsa:1915; P04719; P04720; P68104; Q6IQ15"	"Translation factors; Fragile X syndrome; 2q37 copy number variation syndrome"	"Chaperone Mediated Autophagy; Neutrophil degranulation; Peptide chain elongation; SARS-CoV-1 modulates host translation machinery; Protein methylation; HSF1 activation"	"10"	"14"	"2740.6"	"7545.4"	"6153.6"	"2340.3"	"5129.2"	"3143.6"	"7123.6"	"5420.8"	"6102.6"	"8052.4"	"13219.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5JSL3"	"Dedicator of cytokinesis protein 11 OS=Homo sapiens OX=9606 GN=DOCK11 PE=1 SV=2"	"17"	"31"	"68"	"29"	"2073"	"237.5"	"7.74"	"11233.39"	"104.43"	"25"	"28"	"signal transduction;other biological processes"	"cytosol"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf06920, Pf11878, Pf14429, Pf20421, Pf20422"	"139818"	"ENSG00000147251"	"DOCK11"	"A6NMF0; hsa:139818; Q5JSL3; Q66M66; Q6ZUJ5; Q86VU8; Q96MN3"	""	"Factors involved in megakaryocyte development and platelet production; CDC42 GTPase cycle; RAC1 GTPase cycle"	"3"	"2"	"726.0"	"1415.9"	"1544.5"	"679.0"	"1518.5"	"911.9"	"2015.2"	"2115.9"	"5020.8"	"9306.7"	"11862.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23396"	"40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2"	"75"	"19"	"61"	"19"	"243"	"26.7"	"9.66"	"10798.28"	"103.97"	"18"	"18"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;translational apparatus;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00189, Pf07650"	"6188"	"ENSG00000149273"	"RPS3"	"B2R7N5; hsa:6188; J3KN86; P23396; Q498B5; Q8NI95"	"Cytoplasmic ribosomal proteins"	"GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"1569.0"	"3863.6"	"3689.4"	"1476.9"	"3295.5"	"1560.8"	"3582.7"	"2733.2"	"3657.1"	"5642.1"	"8914.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22234"	"Multifunctional protein ADE2 OS=Homo sapiens OX=9606 GN=PAICS PE=1 SV=3"	"33"	"15"	"57"	"15"	"425"	"47.0"	"7.23"	"10191.37"	"103.30"	"12"	"13"	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00731, Pf01259"	"10606"	"ENSG00000128050"	"PAICS"	"E9PDH9; hsa:10606; P22234; Q68CQ5"	"Metabolic reprogramming in colon cancer"	"Purine ribonucleoside monophosphate biosynthesis"	"2"	"0"	"1897.8"	"2586.0"	"2867.1"	"1855.1"	"2568.9"	"2316.2"	"1901.1"	"1549.2"	"2256.2"	"3335.0"	"6074.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96CW1"	"AP-2 complex subunit mu OS=Homo sapiens OX=9606 GN=AP2M1 PE=1 SV=2"	"51"	"21"	"58"	"21"	"435"	"49.6"	"9.54"	"10814.63"	"103.27"	"16"	"18"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00928, Pf01217"	"1173"	"ENSG00000161203"	"AP2M1"	"A6NE12; D3DNT1; hsa:1173; P20172; P53679; Q96CW1"	"Synaptic vesicle pathway; GABA receptor signaling; EGF/EGFR signaling pathway; Fragile X syndrome; GDNF signaling"	"Potential therapeutics for SARS; EPH-ephrin mediated repulsion of cells; Cargo recognition for clathrin-mediated endocytosis; VLDLR internalisation and degradation; Recycling pathway of L1; MHC class II antigen presentation; WNT5A-dependent internalization of FZD4; LDL clearance; Nef Mediated CD4 Down-regulation; Retrograde neurotrophin signalling; Nef Mediated CD8 Down-regulation; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; Nef mediated downregulation of CD28 cell surface expression; Formation of annular gap junctions"	"21"	"0"	"475.9"	"1021.2"	"1026.7"	"438.9"	"1041.8"	"583.8"	"1302.9"	"2062.1"	"5447.3"	"9383.4"	"14809.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14152"	"Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1"	"25"	"38"	"73"	"38"	"1382"	"166.5"	"6.79"	"13080.92"	"102.71"	"34"	"32"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;translational apparatus;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf01399"	"8661"	"ENSG00000107581"	"EIF3A"	"B1AMV5; B4DYS1; F5H335; hsa:8661; O00653; Q14152; Q15778"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex"	"8"	"0"	"2844.2"	"5175.9"	"5625.2"	"2595.5"	"5146.9"	"3334.1"	"4772.0"	"3641.3"	"5355.1"	"7202.0"	"10394.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HB71"	"Calcyclin-binding protein OS=Homo sapiens OX=9606 GN=CACYBP PE=1 SV=2"	"39"	"14"	"56"	"14"	"228"	"26.2"	"8.25"	"12253.82"	"102.27"	"12"	"11"	"developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf04969, Pf05002, Pf09032"	"27101"	"ENSG00000116161"	"CACYBP"	"B2ZWH2; B3KSF1; hsa:27101; O60666; Q5R370; Q5R371; Q9HB71"	"Gastric cancer network 2"	""	"1"	"0"	"798.4"	"1165.8"	"1351.7"	"677.3"	"1425.2"	"832.7"	"3807.6"	"3290.0"	"5744.7"	"9491.5"	"17348.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P10809"	"60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2"	"44"	"29"	"63"	"29"	"573"	"61.0"	"5.87"	"11165.56"	"102.07"	"26"	"27"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00118"	"3329"	"ENSG00000144381"	"HSPD1"	"B2R5M6; B7Z712; hsa:3329; P10809; Q38L19; Q9UCR6"	"Apoptosis-related network due to altered Notch3 in ovarian cancer; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Mitochondrial protein import; TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"	"4"	"0"	"1496.0"	"11471.2"	"8996.8"	"791.2"	"6470.0"	"2077.2"	"2398.5"	"1742.9"	"2592.1"	"3364.4"	"7668.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P39023"	"60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2"	"45"	"22"	"61"	"22"	"403"	"46.1"	"10.18"	"8347.35"	"101.29"	"17"	"18"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00297"	"6122"	"ENSG00000100316"	"RPL3"	"B2RDV9; hsa:6122; P39023; Q15548; Q5I0G0"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"3603.5"	"7054.7"	"7118.0"	"3117.2"	"6682.3"	"3567.7"	"12671.0"	"9038.3"	"11604.4"	"13549.9"	"19156.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55072"	"Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4"	"37"	"29"	"57"	"29"	"806"	"89.3"	"5.26"	"10994.50"	"100.38"	"26"	"25"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"non-structural extracellular;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00004, Pf02359, Pf02933, Pf09336, Pf17862"	"7415"	"ENSG00000165280"	"VCP"	"B2R5T8; hsa:7415; P55072; Q0V924; Q2TAI5; Q969G7; Q9UCD5"	"Alstrom syndrome; Clock-controlled autophagy in bone metabolism"	"Aggrephagy; Neutrophil degranulation; HSF1 activation; ABC-family proteins mediated transport; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Defective CFTR causes cystic fibrosis; Neddylation; KEAP1-NFE2L2 pathway; E3 ubiquitin ligases ubiquitinate target proteins; Attachment and Entry; Attachment and Entry; Ovarian tumor domain proteases; Josephin domain DUBs; Protein methylation; RHOH GTPase cycle; Translesion Synthesis by POLH; N-glycan trimming in the ER and Calnexin/Calreticulin cycle"	"20"	"0"	"2270.6"	"5230.6"	"5166.4"	"2028.2"	"4673.6"	"2450.9"	"3299.3"	"2792.1"	"4104.1"	"5654.8"	"9093.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P40926"	"Malate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=MDH2 PE=1 SV=3"	"59"	"17"	"58"	"17"	"338"	"35.5"	"8.68"	"9425.86"	"99.42"	"15"	"17"	"other metabolic processes"	"other membranes;mitochondrion;other cell component"	"other molecular function"	"Pf00056, Pf02866"	"4191"	"ENSG00000146701"	"MDH2"	"A8K414; B2RE78; B4DE44; E9PDB2; hsa:4191; O43682; P40926"	"Amino acid metabolism; Metabolic reprogramming in colon cancer; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Glycolysis and gluconeogenesis; TCA cycle (aka Krebs or citric acid cycle)"	"Gluconeogenesis; Citric acid cycle (TCA cycle)"	"7"	"0"	"1874.8"	"3418.7"	"4401.2"	"1603.8"	"3368.2"	"2090.0"	"6039.2"	"5520.8"	"5584.2"	"6791.6"	"10977.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P78527"	"DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3"	"8"	"31"	"61"	"31"	"4128"	"468.8"	"7.12"	"10276.32"	"98.89"	"28"	"28"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00454, Pf02259, Pf02260, Pf08163, Pf19704, Pf20502"	"5591"	"ENSG00000253729"	"PRKDC"	"hsa:5591; P78527; P78528; Q13327; Q13337; Q14175; Q59H99; Q7Z611; Q96SE6; Q9UME3"	"miRNA regulation of DNA damage response; Cell cycle; Retinoblastoma gene in cancer; Fas ligand pathway and stress induction of heat shock proteins; Pathways affected in adenoid cystic carcinoma; ATM signaling in development and disease ; Non-homologous end joining; Osteoblast differentiation and related diseases; DNA repair pathways, full network; DNA damage response"	"E3 ubiquitin ligases ubiquitinate target proteins; Cytosolic sensors of pathogen-associated DNA ; Nonhomologous End-Joining (NHEJ); IRF3-mediated induction of type I IFN"	"14"	"0"	"1367.8"	"3796.0"	"3567.8"	"1227.0"	"3104.3"	"1520.8"	"2388.5"	"1922.3"	"2855.3"	"4362.7"	"6954.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q08211"	"ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4"	"20"	"24"	"55"	"24"	"1270"	"140.9"	"6.84"	"9662.40"	"98.54"	"17"	"21"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;cytoskeleton;translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00035, Pf00270, Pf00271, Pf04408, Pf07717"	"1660"	"ENSG00000135829"	"DHX9"	"B2RNV4; hsa:1660; Q05CI5; Q08211; Q12803; Q32Q22; Q5VY62; Q6PD69; Q99556"	"MECP2 and associated Rett syndrome; mRNA processing"	"mRNA Splicing - Major Pathway; RIP-mediated NFkB activation via ZBP1; DEx/H-box helicases activate type I IFN and inflammatory cytokines production"	"5"	"0"	"1320.9"	"2049.8"	"2197.9"	"1050.7"	"2214.2"	"1316.9"	"3182.8"	"3764.6"	"5266.4"	"5522.6"	"7240.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95782"	"AP-2 complex subunit alpha-1 OS=Homo sapiens OX=9606 GN=AP2A1 PE=1 SV=3"	"21"	"20"	"48"	"13"	"977"	"107.5"	"7.03"	"6156.43"	"98.36"	"13"	"20"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01602, Pf02296, Pf02883"	"160"	"ENSG00000196961"	"AP2A1"	"hsa:160; O95782; Q96CI7; Q96PP6; Q96PP7; Q9H070"	"Synaptic vesicle pathway; VEGFA-VEGFR2 signaling; GABA receptor signaling; EGF/EGFR signaling pathway; Fragile X syndrome; mBDNF and proBDNF regulation of GABA neurotransmission"	"MHC class II antigen presentation; Potential therapeutics for SARS; Recycling pathway of L1; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; LDL clearance; Trafficking of GluR2-containing AMPA receptors; Nef Mediated CD4 Down-regulation; Retrograde neurotrophin signalling; Nef Mediated CD8 Down-regulation; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; VLDLR internalisation and degradation"	"20"	"0"	"207.8"	"496.5"	"500.7"	"212.2"	"560.2"	"309.2"	"625.5"	"866.3"	"2326.2"	"4443.4"	"8129.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11177"	"Pyruvate dehydrogenase E1 component subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=PDHB PE=1 SV=3"	"35"	"12"	"53"	"12"	"359"	"39.2"	"6.65"	"10880.49"	"94.12"	"12"	"12"	"other metabolic processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf02779, Pf02780"	"5162"	"ENSG00000168291"	"PDHB"	"B2R7L0; B4DDD7; hsa:5162; P11177; Q6FH45; Q9BQ27; Q9UFK3"	"Metabolic reprogramming in colon cancer; Orexin receptor pathway"	"Glyoxylate metabolism and glycine degradation; Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid"	"6"	"0"	"1345.3"	"2784.0"	"3138.2"	"1574.3"	"2828.6"	"1749.4"	"3189.4"	"2573.1"	"3478.2"	"3547.3"	"3930.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62701"	"40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2"	"49"	"20"	"60"	"20"	"263"	"29.6"	"10.15"	"9504.26"	"92.99"	"19"	"17"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00467, Pf00900, Pf01479, Pf08071, Pf16121"	"6191"	"ENSG00000198034"	"RPS4X"	"hsa:6191; P12631; P12750; P27576; P55831; P62701; Q14727; Q6IPY4"	"Cytoplasmic ribosomal proteins"	"Major pathway of rRNA processing in the nucleolus and cytosol; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"2703.4"	"4925.9"	"5132.0"	"2481.6"	"4838.3"	"2849.9"	"6786.1"	"5020.4"	"7236.9"	"8802.8"	"11976.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04075"	"Fructose-bisphosphate aldolase A OS=Homo sapiens OX=9606 GN=ALDOA PE=1 SV=2"	"52"	"24"	"60"	"18"	"364"	"39.4"	"8.09"	"11971.23"	"92.68"	"22"	"20"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00274"	"226"	"ENSG00000149925"	"ALDOA"	"B4DXI7; hsa:226; P04075; Q6FH76; Q6FI10; Q96B15; Q9BWD9; Q9UCN2"	"VEGFA-VEGFR2 signaling; Clear cell renal cell carcinoma pathways; Aerobic glycolysis; 16p11.2 proximal deletion syndrome; Glycolysis and gluconeogenesis; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Glycolysis; Gluconeogenesis; Neutrophil degranulation; Platelet degranulation"	"10"	"6"	"4593.3"	"6661.8"	"6699.5"	"3610.0"	"6349.7"	"4554.1"	"5960.5"	"4430.7"	"5510.3"	"6543.9"	"10514.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50570"	"Dynamin-2 OS=Homo sapiens OX=9606 GN=DNM2 PE=1 SV=2"	"38"	"27"	"55"	"27"	"870"	"98.0"	"7.44"	"8713.95"	"92.18"	"21"	"24"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00169, Pf00350, Pf01031, Pf02212"	"1785"	"ENSG00000079805"	"DNM2"	"A8K1B6; E7EV30; E9PEQ4; hsa:1785; K7ESI9; P50570; Q5I0Y0; Q7Z5S3; Q9UPH4"	"Synaptic vesicle pathway; Fragile X syndrome; Intracellular trafficking proteins involved in CMT neuropathy"	"Clathrin-mediated endocytosis; MHC class II antigen presentation; Recycling pathway of L1; Lysosome Vesicle Biogenesis; NGF-stimulated transcription; Golgi Associated Vesicle Biogenesis; Toll Like Receptor 4 (TLR4) Cascade; NOSTRIN mediated eNOS trafficking; Retrograde neurotrophin signalling; Formation of annular gap junctions"	"14"	"0"	"680.0"	"1412.8"	"1407.1"	"631.4"	"1335.0"	"716.8"	"2910.6"	"5393.8"	"5376.1"	"4732.0"	"6895.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43776"	"Asparagine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=NARS1 PE=1 SV=1"	"34"	"19"	"47"	"19"	"548"	"62.9"	"6.25"	"9356.49"	"92.06"	"15"	"17"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00152, Pf01336"	"4677"	"ENSG00000134440"	"NARS1"	"B4DG16; hsa:4677; O43776; Q53GU6"	"Photodynamic therapy-induced unfolded protein response"	"Cytosolic tRNA aminoacylation"	"2"	"0"	"431.0"	"928.3"	"958.3"	"385.8"	"971.5"	"498.0"	"1551.1"	"1357.0"	"3321.9"	"6634.4"	"14414.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P38646"	"Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2"	"35"	"23"	"53"	"22"	"679"	"73.6"	"6.16"	"9451.06"	"91.68"	"19"	"22"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00012"	"3313"	"ENSG00000113013"	"HSPA9"	"B2RCM1; hsa:3313; P30036; P31932; P38646; Q1HB43; Q53H23; Q6GU03; Q9BWB7; Q9UC56"	"Parkin-ubiquitin proteasomal system pathway; Iron-sulfur cluster biogenesis"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Mitochondrial protein import; Regulation of HSF1-mediated heat shock response; Cristae formation"	"6"	"0"	"2002.6"	"5655.6"	"5287.4"	"1632.5"	"4726.1"	"2244.2"	"3033.9"	"2278.3"	"3335.8"	"3763.0"	"6650.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00571"	"ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3"	"35"	"24"	"54"	"23"	"662"	"73.2"	"7.18"	"9480.54"	"90.03"	"20"	"22"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;translation activity;nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"1654"	"ENSG00000215301"	"DDX3X"	"A8K538; B4E3E8; hsa:1654; O00571; O15536"	"Novel intracellular components of RIG-I-like receptor pathway; Hepatitis B infection"	"Neutrophil degranulation"	"3"	"1"	"1649.9"	"2846.3"	"3024.2"	"1598.3"	"2963.5"	"1810.2"	"4366.5"	"3122.0"	"4196.9"	"5454.0"	"7357.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15233"	"Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4"	"34"	"19"	"55"	"18"	"471"	"54.2"	"8.95"	"10640.31"	"88.72"	"18"	"18"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08075"	"4841"	"ENSG00000147140"	"NONO"	"B7Z4C2; D3DVV4; F5GYZ3; hsa:4841; O00201; P30807; Q12786; Q15233; Q9BQC5"	"mRNA processing"	""	"1"	"1"	"1840.4"	"2326.3"	"2747.4"	"1548.7"	"2729.2"	"2001.9"	"3888.7"	"2812.5"	"5151.5"	"6014.9"	"7518.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61978"	"Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1"	"40"	"19"	"47"	"19"	"463"	"50.9"	"5.54"	"8742.82"	"88.53"	"15"	"18"	"RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf08067"	"3190"	"ENSG00000165119"	"HNRNPK"	"hsa:3190; P61978; Q07244; Q15671; Q59F98; Q5T6W4; Q60577; Q6IBN1; Q922Y7; Q96J62"	"mRNA processing; lncRNA in canonical Wnt signaling and colorectal cancer"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA; HCMV Late Events; SUMOylation of RNA binding proteins"	"6"	"0"	"1980.2"	"5459.5"	"4699.2"	"1548.1"	"4249.1"	"2224.1"	"3002.7"	"2416.2"	"3165.2"	"3783.4"	"5832.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62736"	"Actin, aortic smooth muscle OS=Homo sapiens OX=9606 GN=ACTA2 PE=1 SV=1"	"20"	"11"	"54"	"1"	"377"	"42.0"	"5.39"	"9565.91"	"88.09"	"9"	"10"	"developmental processes;other biological processes"	"extracellular matrix;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00022"	"59"	"ENSG00000107796"	"ACTA2"	"B2R8A4; hsa:59; P03996; P04108; P62736; Q6FI19"	"Myometrial relaxation and contraction pathways; Striated muscle contraction pathway; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; 22q11.2 copy number variation syndrome; IL-18 signaling pathway; Regucalcin in proximal tubule epithelial kidney cells; Angiotensin II receptor type 1 pathway; Pleural mesothelioma; CCL18 signaling pathway; Urotensin-II-mediated signaling pathway; Markers of kidney cell lineage; Comprehensive IL-17A signaling; IL-26 signaling pathways; A network map of Macrophage-stimulating protein (MSP) signaling"	"Smooth Muscle Contraction; NOTCH4 Intracellular Domain Regulates Transcription"	"16"	"0"	"64.4"	"620.3"	"475.4"	"69.7"	"352.9"	"104.3"	"170.3"	"129.3"	"224.3"	"255.6"	"533.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25705"	"ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1"	"37"	"18"	"50"	"18"	"553"	"59.7"	"9.13"	"8310.21"	"87.32"	"14"	"17"	"other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;transporter activity;other molecular function"	"Pf00006, Pf00306, Pf02874"	"498"	"ENSG00000152234"	"ATP5F1A"	"A8K092; B4DY56; hsa:498; K7ENP3; P25705; Q53XX6; Q8IXV2; Q96FB4; Q96HW2; Q96IR6; Q9BTV8"	"Electron transport chain: OXPHOS system in mitochondria; 7q11.23 copy number variation syndrome; Oxidative phosphorylation"	"Mitochondrial protein import; Cristae formation; Formation of ATP by chemiosmotic coupling"	"6"	"0"	"1641.2"	"4375.8"	"4102.9"	"1349.6"	"3909.0"	"1843.8"	"2924.0"	"2633.0"	"3632.9"	"4559.3"	"7984.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61247"	"40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2"	"70"	"23"	"63"	"23"	"264"	"29.9"	"9.73"	"11167.56"	"87.28"	"23"	"20"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01015"	"6189"	"ENSG00000145425"	"RPS3A"	"B2R4D4; D3DP05; hsa:6189; P33443; P49241; P61247"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Peptide chain elongation; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"2610.5"	"5224.4"	"5074.9"	"2468.6"	"4655.0"	"2635.5"	"6462.5"	"5363.1"	"7249.9"	"9016.6"	"13194.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06733"	"Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2"	"46"	"19"	"54"	"19"	"434"	"47.1"	"7.39"	"9488.16"	"86.45"	"17"	"18"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00113, Pf03952"	"2023"	"ENSG00000074800"	"ENO1"	"B2RD59; hsa:2023; P06733; P22712; Q16704; Q4TUS4; Q53FT9; Q53HR3; Q658M5; Q6GMP2; Q71V37; Q7Z3V6; Q8WU71; Q96GV1; Q9BT62; Q9UCH6; Q9UM55"	"Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Aerobic glycolysis; IL-18 signaling pathway; Glycolysis and gluconeogenesis"	"Glycolysis; Gluconeogenesis; Manipulation of host energy metabolism"	"8"	"0"	"1477.7"	"8678.4"	"7755.5"	"952.9"	"7428.6"	"2207.6"	"2719.8"	"1636.6"	"2415.1"	"2878.4"	"6574.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06576"	"ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3"	"31"	"15"	"52"	"15"	"529"	"56.5"	"5.40"	"9468.74"	"84.66"	"15"	"15"	"other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;mitochondrion;other cell component"	"signal transduction activity or receptor binding;transporter activity;other molecular function"	"Pf00006, Pf02874"	"506"	"ENSG00000110955"	"ATP5F1B"	"A8K4X0; hsa:506; P06576; Q14283"	"Electron transport chain: OXPHOS system in mitochondria; 7q11.23 copy number variation syndrome; Oxidative phosphorylation"	"Transcriptional activation of mitochondrial biogenesis; Mitochondrial protein import; Cristae formation; Formation of ATP by chemiosmotic coupling"	"7"	"0"	"811.1"	"1973.8"	"1954.0"	"716.5"	"1716.6"	"963.1"	"1538.2"	"1337.9"	"1734.1"	"1934.9"	"3015.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50990"	"T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4"	"41"	"23"	"45"	"23"	"548"	"59.6"	"5.60"	"7775.48"	"84.57"	"19"	"22"	"cell organization and biogenesis;transport;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00118"	"10694"	"ENSG00000156261"	"CCT8"	"A6NN54; B4DEM7; B4DQH4; hsa:10694; P50990; Q4VBP8"	"16p11.2 proximal deletion syndrome"	"Neutrophil degranulation; Association of TriC/CCT with target proteins during biosynthesis; Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; Folding of actin by CCT/TriC"	"8"	"0"	"1216.9"	"3017.4"	"3270.2"	"1075.2"	"2638.7"	"1364.3"	"2032.1"	"1666.0"	"2322.7"	"2931.0"	"4599.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y237"	"Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 OS=Homo sapiens OX=9606 GN=PIN4 PE=1 SV=1"	"79"	"13"	"58"	"13"	"131"	"13.8"	"9.77"	"10429.89"	"83.97"	"11"	"13"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13616"	"5303"	"ENSG00000102309"	"PIN4"	"A8E0G6; B3KXM0; F5H1P5; hsa:5303; Q0D2H3; Q3MHV0; Q52M21; Q5HYW6; Q6IRW4; Q9Y237"	""	""	"0"	"0"	"1050.4"	"1738.3"	"1917.5"	"1020.0"	"1848.2"	"1079.1"	"6647.0"	"5211.4"	"6506.2"	"8634.5"	"10591.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62258"	"14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1"	"52"	"14"	"54"	"12"	"255"	"29.2"	"4.74"	"9532.01"	"82.37"	"13"	"13"	"stress response;transport;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00244"	"7531"	"ENSG00000108953; ENSG00000274474"	"YWHAE"	"B3KY71; D3DTH5; hsa:7531; P29360; P42655; P62258; Q4VJB6; Q53XZ5; Q63631; Q7M4R4"	"Cell cycle; Myometrial relaxation and contraction pathways; VEGFA-VEGFR2 signaling; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"TP53 Regulates Metabolic Genes; Regulation of HSF1-mediated heat shock response; HSF1 activation; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Activation of BAD and translocation to mitochondria ; RAB GEFs exchange GTP for GDP on RABs; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Signaling by Hippo; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models; NADE modulates death signalling"	"25"	"4"	"1221.6"	"4288.4"	"3808.4"	"946.0"	"3162.3"	"1404.2"	"2057.5"	"1871.5"	"2841.2"	"3513.1"	"6167.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P00558"	"Phosphoglycerate kinase 1 OS=Homo sapiens OX=9606 GN=PGK1 PE=1 SV=3"	"43"	"17"	"47"	"17"	"417"	"44.6"	"8.10"	"9178.78"	"82.02"	"15"	"16"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;other membranes;cytosol"	"kinase activity;other molecular function"	"Pf00162"	"5230"	"ENSG00000102144"	"PGK1"	"A8K4W6; B7Z7A9; hsa:5230; P00558; Q5J7W1; Q6IBT6; Q8NI87"	"Cori cycle; Photodynamic therapy-induced HIF-1 survival signaling; VEGFA-VEGFR2 signaling; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Aerobic glycolysis; Glycolysis in senescence; Glycolysis and gluconeogenesis"	"Glycolysis; Gluconeogenesis; Manipulation of host energy metabolism"	"11"	"0"	"1023.9"	"5279.0"	"4310.4"	"650.9"	"3969.3"	"1416.6"	"2236.1"	"1761.9"	"2495.8"	"5030.5"	"18602.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q00688"	"Peptidyl-prolyl cis-trans isomerase FKBP3 OS=Homo sapiens OX=9606 GN=FKBP3 PE=1 SV=1"	"52"	"18"	"49"	"18"	"224"	"25.2"	"9.28"	"7095.57"	"81.88"	"15"	"17"	""	"nucleus"	"other molecular function"	"Pf00254, Pf18410"	"2287"	"ENSG00000100442"	"FKBP3"	"B2R4Q9; hsa:2287; Q00688; Q14317"	""	""	"0"	"0"	"491.5"	"1004.2"	"1058.4"	"459.1"	"1088.5"	"551.1"	"3787.0"	"3224.8"	"5079.9"	"8887.3"	"16643.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P18124"	"60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1"	"51"	"15"	"55"	"15"	"248"	"29.2"	"10.65"	"9887.83"	"80.19"	"15"	"12"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00327, Pf08079"	"6129"	"ENSG00000147604"	"RPL7"	"A8K504; hsa:6129; P18124; Q15289; Q3KQU0; Q5I0X1; Q6IBM9"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"15"	"0"	"1222.5"	"3004.7"	"2703.0"	"1079.5"	"2664.3"	"1095.6"	"4035.6"	"3616.3"	"4320.6"	"5997.4"	"8192.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12906"	"Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3"	"22"	"18"	"44"	"18"	"894"	"95.3"	"8.76"	"7179.48"	"80.06"	"15"	"18"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00035, Pf07528"	"3609"	"ENSG00000129351"	"ILF3"	"A8K6F2; G5E9M5; hsa:3609; O43409; Q12906; Q6P1X1; Q86XY7; Q99544; Q99545; Q9BZH4; Q9BZH5; Q9NQ95; Q9NQ96; Q9NQ97; Q9NQ98; Q9NQ99; Q9NQA0; Q9NQA1; Q9NQA2; Q9NRN2; Q9NRN3; Q9NRN4; Q9UMZ9; Q9UN00; Q9UN84; Q9UNA2"	""	"Regulation of CDH11 gene transcription"	"1"	"0"	"903.0"	"2013.9"	"1968.8"	"873.3"	"1994.4"	"1076.0"	"2196.0"	"1702.0"	"2271.1"	"2753.7"	"4132.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P67809"	"Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3"	"49"	"12"	"36"	"9"	"324"	"35.9"	"9.88"	"5080.04"	"78.84"	"6"	"12"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00313"	"4904"	"ENSG00000065978"	"YBX1"	"hsa:4904; P16990; P16991; P67809; Q14972; Q15325; Q5FVF0"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; MECP2 and associated Rett syndrome; mRNA processing; Sudden infant death syndrome (SIDS) susceptibility pathways"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA; SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Interferon gamma signaling; mRNA Splicing - Minor Pathway; Noncanonical activation of NOTCH3"	"10"	"4"	"580.4"	"1083.5"	"1108.7"	"466.4"	"1096.6"	"546.4"	"1114.9"	"935.5"	"1153.2"	"1380.6"	"1980.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q00839"	"Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6"	"25"	"23"	"44"	"22"	"825"	"90.5"	"6.00"	"6862.06"	"78.33"	"15"	"19"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00622, Pf02037, Pf13671"	"3192"	"ENSG00000153187"	"HNRNPU"	"hsa:3192; O75507; Q00839; Q8N174; Q96HY9; Q9BQ09"	"mRNA processing; lncRNA in canonical Wnt signaling and colorectal cancer"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"4"	"1"	"2424.1"	"5953.3"	"5871.1"	"2313.1"	"5223.2"	"2659.4"	"4488.4"	"3181.2"	"4368.6"	"5152.8"	"8078.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46777"	"60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3"	"47"	"14"	"46"	"14"	"297"	"34.3"	"9.72"	"10340.21"	"78.20"	"14"	"14"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf14204, Pf17144"	"6125"	"ENSG00000122406"	"RPL5"	"hsa:6125; P46777; Q32LZ3; Q53HH6; Q9H3F4"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"Major pathway of rRNA processing in the nucleolus and cytosol; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"15"	"0"	"1317.2"	"3014.4"	"2770.4"	"1131.2"	"2693.9"	"1304.8"	"5414.6"	"4829.6"	"5536.6"	"6212.6"	"8563.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EK5"	"KIF-binding protein OS=Homo sapiens OX=9606 GN=KIFBP PE=1 SV=1"	"37"	"18"	"43"	"18"	"621"	"71.8"	"5.49"	"7696.13"	"77.73"	"15"	"16"	"cell organization and biogenesis;transport;developmental processes"	"cytoskeleton;mitochondrion"	"cytoskeletal activity"	"Pf12309"	"26128"	"ENSG00000198954"	"KIFBP"	"A8K5M8; hsa:26128; Q96EK5; Q9BR89; Q9ULE1; Q9Y428"	""	""	"0"	"0"	"389.5"	"687.5"	"765.0"	"371.4"	"802.2"	"523.5"	"1233.4"	"2239.4"	"6682.4"	"10837.6"	"15413.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14683"	"Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2"	"22"	"25"	"44"	"25"	"1233"	"143.1"	"7.64"	"6920.66"	"77.23"	"21"	"22"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02463, Pf06470"	"8243"	"ENSG00000072501"	"SMC1A"	"hsa:8243; O14995; Q14683; Q16351; Q2M228"	"miRNA regulation of DNA damage response; Cell cycle; Retinoblastoma gene in cancer; Constitutive androstane receptor pathway; Nuclear receptors meta-pathway; Pathways affected in adenoid cystic carcinoma; ATM signaling in development and disease ; mRNA processing; Regulation of sister chromatid separation at the metaphase-anaphase transition; Rett syndrome causing genes; CAMKK2 pathway; Cohesin complex - Cornelia de Lange syndrome; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; DNA damage response"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Estrogen-dependent gene expression; Meiotic synapsis; SUMOylation of DNA damage response and repair proteins; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"21"	"0"	"1191.1"	"1819.9"	"2117.0"	"1102.6"	"2112.2"	"1299.8"	"2787.3"	"2062.8"	"3306.5"	"4953.0"	"7329.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31946"	"14-3-3 protein beta/alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3"	"52"	"12"	"41"	"5"	"246"	"28.1"	"4.83"	"7722.67"	"76.84"	"11"	"11"	"transport;signal transduction;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00244"	"7529"	"ENSG00000166913"	"YWHAB"	"A8K9K2; E1P616; hsa:7529; P31946"	"Cell cycle; IL-3 signaling pathway; Myometrial relaxation and contraction pathways; Hepatitis B infection; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"TP53 Regulates Metabolic Genes; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Signaling by BRAF and RAF1 fusions; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; Regulation of localization of FOXO transcription factors; mTORC1-mediated signalling; Signaling by Hippo; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RAF activation; SHOC2 M1731 mutant abolishes MRAS complex function; Gain-of-function MRAS complexes activate RAF signaling; RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Rap1 signalling; Negative regulation of MAPK pathway; Frs2-mediated activation; ARMS-mediated activation; Activation of BAD and translocation to mitochondria ; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"	"33"	"5"	"525.0"	"1602.0"	"1340.5"	"467.9"	"1221.2"	"584.1"	"910.8"	"917.2"	"1267.4"	"1619.6"	"2736.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14008"	"Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3"	"13"	"24"	"49"	"24"	"2032"	"225.4"	"7.80"	"9493.46"	"76.77"	"21"	"21"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02985, Pf12348"	"9793"	"ENSG00000175216"	"CKAP5"	"hsa:9793; Q05D70; Q0VAX7; Q0VAX8; Q14008; Q14668; Q2TA89; Q6NSH4"	""	"Separation of Sister Chromatids; Regulation of PLK1 Activity at G2/M Transition; RHO GTPases Activate Formins; Resolution of Sister Chromatid Cohesion; Recruitment of NuMA to mitotic centrosomes; EML4 and NUDC in mitotic spindle formation; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"13"	"0"	"1397.1"	"2022.5"	"2294.0"	"1284.6"	"2347.6"	"1606.3"	"3120.1"	"2198.9"	"3150.7"	"4125.7"	"5489.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30101"	"Protein disulfide-isomerase A3 OS=Homo sapiens OX=9606 GN=PDIA3 PE=1 SV=4"	"44"	"20"	"41"	"20"	"505"	"56.7"	"6.35"	"6768.27"	"76.24"	"17"	"19"	"cell adhesion;cell organization and biogenesis;stress response;signal transduction;other biological processes"	"non-structural extracellular;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00085, Pf13848"	"2923"	"ENSG00000167004"	"PDIA3"	"hsa:2923; P30101; Q13453; Q14255; Q8IYF8; Q9UMU7"	"Prion disease pathway"	"ER-Phagosome pathway; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Calnexin/calreticulin cycle"	"4"	"0"	"800.4"	"2831.5"	"2636.0"	"805.6"	"2348.2"	"1106.7"	"2287.9"	"1906.5"	"2314.9"	"2771.6"	"4547.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04259"	"Keratin, type II cytoskeletal 6B OS=Homo sapiens OX=9606 GN=KRT6B PE=1 SV=5"	"30"	"19"	"48"	"1"	"564"	"60.0"	"8.00"	"7740.00"	"75.80"	"17"	"19"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton"	"bone, tooth or skin structural activity;cytoskeletal activity"	"Pf00038, Pf16208"	"3854"	"ENSG00000185479"	"KRT6B"	"hsa:3854; P04259; P48669"	""	"Formation of the cornified envelope"	"2"	"16"	"573.4"	"1375.8"	"20829.2"	"509.4"	"376.8"	"1068.7"	"1147.3"	"1406.6"	"1618.8"	"1963.3"	"1995.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P26373"	"60S ribosomal protein L13 OS=Homo sapiens OX=9606 GN=RPL13 PE=1 SV=4"	"57"	"16"	"50"	"16"	"211"	"24.2"	"11.65"	"8051.24"	"74.59"	"12"	"16"	"protein metabolism;other metabolic processes;developmental processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01294"	"6137"	"ENSG00000167526"	"RPL13"	"B4DLX3; F5H1S2; hsa:6137; P26373; Q3KQT8; Q567Q8; Q9BPX0"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"1536.3"	"2976.3"	"3243.4"	"1312.1"	"3322.2"	"1661.6"	"5744.2"	"4390.5"	"5459.7"	"6343.4"	"8046.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14204"	"Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5"	"7"	"28"	"46"	"28"	"4646"	"532.1"	"6.40"	"6640.32"	"74.23"	"20"	"26"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03028, Pf08385, Pf08393, Pf12774, Pf12775, Pf12777, Pf12780, Pf12781, Pf17852, Pf18198, Pf18199"	"1778"	"ENSG00000197102"	"DYNC1H1"	"B0I1R0; hsa:1778; Q14204; Q6DKQ7; Q8WU28; Q92814; Q9Y4G5"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein"	"Separation of Sister Chromatids; Neutrophil degranulation; MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; HCMV Early Events; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Aggrephagy; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"22"	"0"	"655.4"	"1622.7"	"1666.6"	"598.6"	"1503.1"	"711.3"	"1395.1"	"1116.6"	"1669.5"	"2544.4"	"3682.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P53396"	"ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3"	"17"	"19"	"47"	"19"	"1101"	"120.8"	"7.33"	"8567.34"	"73.49"	"18"	"18"	"other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00285, Pf00549, Pf02629, Pf16114"	"47"	"ENSG00000131473"	"ACLY"	"B4DIM0; B4E3P0; hsa:47; P53396; Q13037; Q9BRL0"	"Sterol regulatory element-binding proteins (SREBP) signaling; TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Fatty acid biosynthesis; Amino acid metabolism; Lipid metabolism pathway; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer"	"Neutrophil degranulation; ChREBP activates metabolic gene expression; Fatty acyl-CoA biosynthesis"	"10"	"0"	"2121.5"	"4836.7"	"4217.7"	"1686.9"	"4074.6"	"1956.2"	"2935.7"	"2304.3"	"3028.6"	"3817.8"	"5884.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NC51"	"Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2"	"39"	"20"	"45"	"20"	"408"	"44.9"	"8.65"	"10979.11"	"73.28"	"18"	"13"	"cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf04774, Pf16174"	"26135"	"ENSG00000142864"	"SERBP1"	"hsa:26135; Q5VU19; Q5VU20; Q5VU22; Q8NC51; Q8WUH0; Q96SE2; Q9BTY3; Q9BUM4; Q9Y367; Q9Y4S3"	"Apoptosis-related network due to altered Notch3 in ovarian cancer"	""	"1"	"0"	"2244.9"	"3507.9"	"4018.7"	"2013.0"	"3871.5"	"2447.2"	"6972.5"	"4766.1"	"6800.5"	"7379.4"	"9784.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P32121"	"Beta-arrestin-2 OS=Homo sapiens OX=9606 GN=ARRB2 PE=1 SV=2"	"38"	"13"	"37"	"12"	"409"	"46.1"	"7.69"	"6904.67"	"73.21"	"10"	"13"	"cell-cell signaling;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00339, Pf02752"	"409"	"ENSG00000141480"	"ARRB2"	"B4DLW0; B5B0C0; B7WPL3; D3DTK2; H0Y688; hsa:409; P32121; Q0Z8D3; Q2PP19; Q6ICT3; Q8N7Y2; Q9UEQ6"	"Corticotropin-releasing hormone signaling pathway; Complement system; Myometrial relaxation and contraction pathways; Wnt signaling pathway; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Hedgehog signaling pathway; Gastrin signaling pathway; Kisspeptin/kisspeptin receptor system in the ovary; GPR143 in melanocytes and retinal pigment epithelium cells; Calcium regulation in cardiac cells"	"Ub-specific processing proteases; Thrombin signalling through proteinase activated receptors (PARs); Activated NOTCH1 Transmits Signal to the Nucleus; Cargo recognition for clathrin-mediated endocytosis; Activation of SMO; G alpha (s) signalling events; Signaling by BRAF and RAF1 fusions; WNT5A-dependent internalization of FZD4; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants"	"27"	"0"	"254.7"	"421.9"	"443.0"	"216.1"	"488.7"	"286.2"	"739.0"	"1314.4"	"2931.5"	"3919.0"	"5957.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35637"	"RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1"	"18"	"9"	"29"	"6"	"526"	"53.4"	"9.36"	"4552.30"	"72.57"	"6"	"8"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00641"	"2521"	"ENSG00000089280"	"FUS"	"hsa:2521; P35637; Q9H4A8"	"MECP2 and associated Rett syndrome; mRNA processing"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"4"	"4"	"1273.0"	"1997.9"	"2109.9"	"1104.8"	"1827.3"	"1327.5"	"2775.4"	"2140.6"	"3021.3"	"3191.5"	"4376.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60891"	"Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2"	"46"	"14"	"43"	"7"	"318"	"34.8"	"6.98"	"7628.08"	"72.11"	"14"	"13"	"other metabolic processes;developmental processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf13793, Pf14572"	"5631"	"ENSG00000147224"	"PRPS1"	"B1ALA8; B2R6T7; B4DNL6; D3DUX6; hsa:5631; P09329; P60891"	""	"5-Phosphoribose 1-diphosphate biosynthesis"	"1"	"5"	"835.7"	"1390.3"	"1300.3"	"674.3"	"1215.4"	"899.8"	"1258.4"	"1257.8"	"1918.0"	"3214.1"	"5579.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q06830"	"Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1"	"49"	"13"	"46"	"12"	"199"	"22.1"	"8.13"	"7692.77"	"72.11"	"12"	"12"	"cell cycle OR cell proliferation;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00578, Pf10417"	"5052"	"ENSG00000117450"	"PRDX1"	"B5BU26; D3DPZ8; hsa:5052; P35703; Q06830; Q2V576; Q5T154; Q5T155"	"Androgen receptor signaling pathway; Selenium micronutrient network; Nuclear receptors meta-pathway; NRF2 pathway"	"Detoxification of Reactive Oxygen Species; TP53 Regulates Metabolic Genes; NFE2L2 regulating anti-oxidant/detoxification enzymes; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"	"8"	"1"	"1210.5"	"3556.1"	"3272.1"	"856.5"	"2668.1"	"1254.1"	"2526.7"	"1942.9"	"2692.6"	"3107.3"	"5199.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P57772"	"Selenocysteine-specific elongation factor OS=Homo sapiens OX=9606 GN=EEFSEC PE=1 SV=4"	"22"	"13"	"40"	"13"	"596"	"65.3"	"8.35"	"8075.38"	"71.58"	"13"	"13"	"protein metabolism;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009"	"60678"	"ENSG00000132394; ENSG00000284869"	"EEFSEC"	"hsa:60678; P57772; Q96HZ6"	""	"Selenocysteine synthesis"	"1"	"0"	"251.7"	"499.6"	"550.1"	"243.6"	"572.3"	"334.8"	"1136.2"	"2047.0"	"3626.5"	"5974.0"	"7924.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08865"	"40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4"	"55"	"15"	"32"	"15"	"295"	"32.8"	"4.87"	"4983.01"	"71.40"	"11"	"13"	"cell adhesion;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;translational apparatus;nucleus;other cell component"	"translation activity;other molecular function"	"Pf00318, Pf16122"	"3921"	"ENSG00000168028"	"RPSA"	"hsa:3921; P08865; P11085; P12030; Q16471; Q6IPD1; Q6IPD2; Q6NSD1; Q6NXQ8; Q86VC0"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"366.9"	"1124.3"	"1188.5"	"335.2"	"1024.7"	"446.7"	"1304.3"	"1036.6"	"1645.4"	"2116.2"	"2987.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P34932"	"Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4"	"32"	"25"	"49"	"23"	"840"	"94.3"	"5.19"	"8676.64"	"71.16"	"24"	"22"	"cell organization and biogenesis;stress response;transport;other biological processes"	"non-structural extracellular;cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf00012"	"3308"	"ENSG00000170606"	"HSPA4"	"hsa:3308; O95756; P34932; Q2TAL4; Q9BUK9"	"Parkin-ubiquitin proteasomal system pathway"	"Regulation of HSF1-mediated heat shock response"	"2"	"2"	"1641.6"	"5592.8"	"5448.3"	"1539.7"	"5104.4"	"2142.7"	"2917.6"	"2079.6"	"2940.3"	"3353.5"	"6274.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13010"	"X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3"	"30"	"20"	"46"	"20"	"732"	"82.7"	"5.81"	"6628.31"	"71.15"	"14"	"17"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf02735, Pf03730, Pf03731, Pf08785"	"7520"	"ENSG00000079246"	"XRCC5"	"A8K3X5; hsa:7520; P13010; Q0Z7V0; Q4VBQ5; Q53HH7; Q7M4N0; Q9UCQ0; Q9UCQ1"	"Non-homologous end joining; Male infertility; DNA repair pathways, full network; p53 transcriptional gene network; 10q11.21q11.23 copy number variation syndrome"	"Neutrophil degranulation; Cytosolic sensors of pathogen-associated DNA ; Nonhomologous End-Joining (NHEJ); 2-LTR circle formation; IRF3-mediated induction of type I IFN"	"10"	"0"	"1444.4"	"3969.2"	"3678.3"	"1212.7"	"3208.6"	"1655.0"	"2587.9"	"1693.0"	"2475.1"	"2917.4"	"4881.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63104"	"14-3-3 protein zeta/delta OS=Homo sapiens OX=9606 GN=YWHAZ PE=1 SV=1"	"62"	"14"	"41"	"10"	"245"	"27.7"	"4.79"	"5962.42"	"70.97"	"10"	"13"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00244"	"7534"	"ENSG00000164924"	"YWHAZ"	"A8K1N0; B7Z465; hsa:7534; P29213; P29312; P63104; Q32P43; Q5XJ08; Q6GPI2; Q6IN74; Q6NUR9; Q6P3U9; Q86V33"	"Cell cycle; Prolactin signaling pathway; Pathogenic Escherichia coli infection; Myometrial relaxation and contraction pathways; Hepatitis B infection; GDNF signaling; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Negative regulation of NOTCH4 signaling; Regulation of localization of FOXO transcription factors; Deactivation of the beta-catenin transactivating complex; Interleukin-3, Interleukin-5 and GM-CSF signaling; TP53 Regulates Metabolic Genes; NOTCH4 Activation and Transmission of Signal to the Nucleus; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; Rap1 signalling; KSRP (KHSRP) binds and destabilizes mRNA; GP1b-IX-V activation signalling; Activation of BAD and translocation to mitochondria"	"23"	"2"	"554.3"	"2089.9"	"1865.4"	"444.8"	"1560.4"	"673.1"	"1080.0"	"885.7"	"1384.7"	"1779.7"	"3216.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51659"	"Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3"	"37"	"20"	"38"	"20"	"736"	"79.6"	"8.84"	"6934.07"	"70.81"	"16"	"18"	"other metabolic processes;developmental processes"	"cytosol;other cytoplasmic organelle"	"other molecular function"	"Pf00106, Pf01575, Pf02036"	"3295"	"ENSG00000133835"	"HSD17B4"	"B4DNV1; B4DVS5; E9PB82; F5HE57; hsa:3295; P51659"	"Androgen receptor network in prostate cancer; Steroid biosynthesis; Disorders of bile acid synthesis and biliary transport; Primary ovarian insufficiency"	"TYSND1 cleaves peroxisomal proteins; Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol; alpha-linolenic acid (ALA) metabolism; Beta-oxidation of pristanoyl-CoA; Beta-oxidation of very long chain fatty acids"	"10"	"0"	"1221.0"	"2179.3"	"2274.0"	"1137.6"	"2151.6"	"1366.7"	"1878.6"	"1455.1"	"2268.9"	"3545.6"	"5885.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99497"	"Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2"	"67"	"14"	"39"	"14"	"189"	"19.9"	"6.79"	"7428.00"	"70.43"	"12"	"12"	"cell-cell signaling;cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf01965"	"11315"	"ENSG00000116288"	"PARK7"	"B2R4Z1; hsa:11315; O14805; Q6DR95; Q7LFU2; Q99497"	"Androgen receptor signaling pathway; Synaptic vesicle pathway; Parkinson's disease pathway"	"Late endosomal microautophagy; Aggrephagy; SUMOylation of transcription cofactors; Chaperone Mediated Autophagy"	"7"	"0"	"2485.5"	"4115.4"	"4588.0"	"2279.9"	"3796.1"	"2548.9"	"3297.1"	"2751.4"	"3999.2"	"4515.3"	"6485.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00159"	"Unconventional myosin-Ic OS=Homo sapiens OX=9606 GN=MYO1C PE=1 SV=4"	"20"	"17"	"33"	"17"	"1063"	"121.6"	"9.41"	"4655.20"	"69.81"	"10"	"16"	"cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00063, Pf00612, Pf06017"	"4641"	"ENSG00000197879"	"MYO1C"	"hsa:4641; O00159; Q4LE56; Q6NVJ7; Q86Y95"	"VEGFA-VEGFR2 signaling; Insulin signaling"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea"	"7"	"0"	"262.2"	"594.5"	"608.0"	"240.8"	"585.1"	"345.4"	"931.8"	"1378.2"	"2723.4"	"4658.9"	"7275.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P17987"	"T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1"	"40"	"17"	"38"	"17"	"556"	"60.3"	"6.11"	"7218.67"	"69.76"	"14"	"16"	"cell organization and biogenesis;transport;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf00118"	"6950"	"ENSG00000120438"	"TCP1"	"E1P5B2; hsa:6950; P17987; Q15556; Q5TCM3"	"16p11.2 proximal deletion syndrome"	"Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; Folding of actin by CCT/TriC"	"8"	"0"	"1281.9"	"3366.4"	"3477.9"	"977.2"	"2810.8"	"1264.3"	"1631.9"	"1306.0"	"2075.7"	"2586.6"	"4299.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92945"	"Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4"	"29"	"16"	"34"	"13"	"711"	"73.1"	"7.30"	"5888.12"	"69.50"	"13"	"15"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf09005"	"8570"	"ENSG00000088247"	"KHSRP"	"hsa:8570; O00301; Q59EZ9; Q5U4P6; Q92945; Q9UNT5; Q9UQH5"	"Pre-implantation embryo"	"ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA"	"3"	"0"	"692.7"	"2391.5"	"2115.6"	"574.0"	"1820.6"	"741.1"	"1076.4"	"835.5"	"1233.7"	"1519.2"	"2515.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TCS8"	"Polyribonucleotide nucleotidyltransferase 1, mitochondrial OS=Homo sapiens OX=9606 GN=PNPT1 PE=1 SV=2"	"29"	"19"	"42"	"19"	"783"	"85.9"	"7.77"	"8312.43"	"68.62"	"18"	"17"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"other membranes;cytosol;mitochondrion;ER/Golgi;translational apparatus;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf01138, Pf03725, Pf03726"	"87178"	"ENSG00000138035"	"PNPT1"	"hsa:87178; Q53SU0; Q68CN1; Q7Z7D1; Q8IWX1; Q8TCS8; Q96T05; Q9BRU3; Q9BVX0"	"Pyrimidine metabolism; miRNA degrading enzymes"	""	"2"	"0"	"1063.0"	"1492.4"	"1735.3"	"916.1"	"1643.3"	"1050.4"	"2511.4"	"1963.3"	"2862.1"	"3454.1"	"4826.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50991"	"T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4"	"39"	"18"	"43"	"18"	"539"	"57.9"	"7.83"	"8159.74"	"68.50"	"15"	"16"	"transport;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00118"	"10575"	"ENSG00000115484"	"CCT4"	"B2R6I3; B7Z8B1; F5H5W3; hsa:10575; O14870; P50991; Q53QP9; Q96C51"	"16p11.2 proximal deletion syndrome"	"Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; Folding of actin by CCT/TriC"	"7"	"0"	"1254.7"	"3153.2"	"3150.9"	"1041.4"	"2622.8"	"1320.0"	"1690.7"	"1216.4"	"1783.7"	"2214.6"	"3533.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NSD9"	"Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3"	"32"	"19"	"41"	"19"	"589"	"66.1"	"6.84"	"6479.10"	"67.92"	"16"	"18"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03483, Pf03484, Pf17759, Pf18262"	"10056"	"ENSG00000116120"	"FARSB"	"B4DFM0; hsa:10056; O95708; Q4ZFX1; Q57ZJ5; Q9NSD9; Q9NZZ6"	"VEGFA-VEGFR2 signaling; Amino acid metabolism"	"Cytosolic tRNA aminoacylation"	"3"	"0"	"1583.5"	"2507.8"	"2831.0"	"1493.4"	"2687.4"	"1662.9"	"3411.7"	"2662.9"	"3950.5"	"5215.0"	"7557.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92841"	"Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2"	"27"	"18"	"38"	"13"	"729"	"80.2"	"8.27"	"6620.91"	"67.79"	"16"	"17"	"RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"10521"	"ENSG00000100201"	"DDX17"	"B1AHM0; H3BLZ8; hsa:10521; Q69YT1; Q6ICD6; Q92841"	"Novel intracellular components of RIG-I-like receptor pathway"	"SUMOylation of transcription cofactors"	"2"	"5"	"768.5"	"1504.1"	"1546.7"	"735.2"	"1495.5"	"924.7"	"2084.6"	"1593.5"	"2123.7"	"2657.2"	"3599.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62424"	"60S ribosomal protein L7a OS=Homo sapiens OX=9606 GN=RPL7A PE=1 SV=2"	"44"	"16"	"46"	"16"	"266"	"30.0"	"10.61"	"8865.08"	"67.72"	"15"	"13"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01248"	"6130"	"ENSG00000148303; ENSG00000280858"	"RPL7A"	"hsa:6130; P11518; P62424; Q5T8U4"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"1309.7"	"2635.9"	"2633.6"	"1119.2"	"2536.7"	"1285.7"	"4248.5"	"3283.1"	"4273.7"	"5054.5"	"7117.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q04837"	"Single-stranded DNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SSBP1 PE=1 SV=1"	"64"	"10"	"34"	"10"	"148"	"17.2"	"9.60"	"5801.79"	"67.31"	"9"	"10"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00436"	"6742"	"ENSG00000106028; ENSG00000262771"	"SSBP1"	"hsa:6742; Q04837"	""	"Transcriptional activation of mitochondrial biogenesis"	"1"	"0"	"767.0"	"1755.7"	"1781.2"	"651.2"	"1670.8"	"768.4"	"1842.9"	"1482.2"	"2002.5"	"2515.2"	"3431.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92499"	"ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2"	"29"	"17"	"37"	"17"	"740"	"82.4"	"7.23"	"6741.14"	"66.12"	"13"	"15"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf00622"	"1653"	"ENSG00000079785"	"DDX1"	"B4DME8; B4DPN6; hsa:1653; Q92499"	"DDX1 as a regulatory component of the Drosha microprocessor; mRNA processing"	"tRNA processing in the nucleus"	"3"	"0"	"937.1"	"1395.9"	"1614.7"	"705.8"	"1496.0"	"950.2"	"2145.5"	"1515.6"	"2201.5"	"2809.6"	"4305.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05455"	"Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2"	"29"	"12"	"38"	"12"	"408"	"46.8"	"7.12"	"7527.99"	"65.36"	"12"	"12"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf05383, Pf08777"	"6741"	"ENSG00000138385"	"SSB"	"hsa:6741; P05455; Q15367; Q53XJ4"	""	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Termination"	"2"	"0"	"1318.2"	"3923.6"	"3842.8"	"1217.8"	"3657.4"	"1622.6"	"2574.0"	"1683.1"	"2652.1"	"2995.0"	"5330.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35527"	"Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3"	"31"	"15"	"35"	"14"	"623"	"62.0"	"5.24"	"5830.06"	"64.91"	"12"	"12"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton"	"cytoskeletal activity"	"Pf00038"	"3857"	"ENSG00000171403"	"KRT9"	"hsa:3857; O00109; P35527; Q0IJ47; Q14665"	""	"Formation of the cornified envelope"	"2"	"0"	"772.5"	"1941.7"	"11943.9"	"354.8"	"264.1"	"492.1"	"770.5"	"824.1"	"2434.6"	"3049.3"	"1277.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13645"	"Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6"	"23"	"19"	"42"	"14"	"584"	"58.8"	"5.21"	"7658.12"	"64.79"	"17"	"17"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;cytosol;cytoskeleton;other cell component"	"bone, tooth or skin structural activity;other molecular function"	"Pf00038"	"3858"	"ENSG00000186395"	"KRT10"	"hsa:3858; P13645; Q14664; Q8N175"	""	"Formation of the cornified envelope"	"2"	"7"	"1095.5"	"2343.9"	"9457.3"	"1020.1"	"1049.0"	"955.3"	"1521.6"	"2999.2"	"3644.2"	"3472.3"	"3137.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P02538"	"Keratin, type II cytoskeletal 6A OS=Homo sapiens OX=9606 GN=KRT6A PE=1 SV=3"	"29"	"18"	"42"	"1"	"564"	"60.0"	"8.00"	"6840.70"	"64.56"	"16"	"18"	"cell organization and biogenesis;stress response;other biological processes"	"cytosol;cytoskeleton"	"bone, tooth or skin structural activity;cytoskeletal activity"	"Pf00038, Pf16208"	"3853"	"ENSG00000205420"	"KRT6A"	"A4QPC1; hsa:3853; P02538; P48667; Q08AR4; Q6NT67; Q96CL4"	"Ectoderm differentiation; Ectoderm differentiation; Pancreatic cancer subtypes"	"Formation of the cornified envelope"	"5"	"1"	"77.9"	"234.4"	"4895.3"	"74.9"	"16.9"	"210.0"	"119.5"	"84.3"	"202.6"	"193.2"	"181.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14625"	"Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1"	"26"	"19"	"40"	"18"	"803"	"92.4"	"4.84"	"6507.52"	"64.32"	"18"	"18"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00183, Pf02518"	"7184"	"ENSG00000166598"	"HSP90B1"	"hsa:7184; P14625; Q96A97"	"Photodynamic therapy-induced unfolded protein response; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Prion disease pathway; PI3K-Akt signaling pathway; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Interleukin-4 and Interleukin-13 signaling; Trafficking and processing of endosomal TLR; Scavenging by Class A Receptors; ATF6 (ATF6-alpha) activates chaperone genes"	"11"	"0"	"930.7"	"6478.3"	"4933.1"	"560.5"	"4648.9"	"1137.5"	"1300.2"	"1076.0"	"1766.6"	"2330.4"	"4379.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96AE4"	"Far upstream element-binding protein 1 OS=Homo sapiens OX=9606 GN=FUBP1 PE=1 SV=3"	"24"	"17"	"43"	"12"	"644"	"67.5"	"7.61"	"7376.96"	"64.09"	"17"	"16"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00013, Pf09005"	"8880"	"ENSG00000162613"	"FUBP1"	"hsa:8880; Q12828; Q96AE4"	""	""	"0"	"5"	"1070.6"	"3859.2"	"3287.1"	"1019.5"	"3103.2"	"1373.1"	"2517.5"	"2189.4"	"2896.3"	"4506.6"	"7550.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52272"	"Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3"	"29"	"17"	"34"	"17"	"730"	"77.5"	"8.70"	"5648.76"	"63.88"	"14"	"15"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf11532"	"4670"	"ENSG00000099783"	"HNRNPM"	"hsa:4670; P52272; Q15584; Q8WZ44; Q96H56; Q9BWL9; Q9Y492"	"mRNA processing"	"Processing of Capped Intron-Containing Pre-mRNA; mRNA Splicing - Major Pathway; FGFR2 alternative splicing"	"4"	"0"	"1099.3"	"3398.3"	"3088.7"	"993.7"	"2889.6"	"1213.8"	"2108.4"	"1693.5"	"2251.3"	"3419.2"	"5374.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35908"	"Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2"	"25"	"15"	"38"	"8"	"639"	"65.4"	"8.00"	"6473.19"	"63.87"	"15"	"15"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;cytosol;cytoskeleton;other cell component"	"bone, tooth or skin structural activity;cytoskeletal activity"	"Pf00038, Pf16208"	"3849"	"ENSG00000172867"	"KRT2"	"hsa:3849; P35908; Q4VAQ2"	""	"Formation of the cornified envelope"	"2"	"0"	"781.3"	"573.3"	"1623.5"	"631.6"	"571.8"	"269.9"	"600.8"	"2555.4"	"1391.3"	"1504.0"	"977.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62937"	"Peptidyl-prolyl cis-trans isomerase A OS=Homo sapiens OX=9606 GN=PPIA PE=1 SV=2"	"64"	"12"	"43"	"12"	"165"	"18.0"	"7.81"	"7562.82"	"63.21"	"10"	"10"	"cell adhesion;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00160"	"5478"	"ENSG00000196262"	"PPIA"	"A8K220; hsa:5478; P05092; P62937; Q3KQW3; Q567Q0; Q6IBU5; Q96IX3; Q9BRU4; Q9BTY9; Q9UC61"	"Prolactin signaling pathway"	"Neutrophil degranulation; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Budding and maturation of HIV virion; Platelet degranulation ; Basigin interactions; SARS-CoV-1 activates/modulates innate immune responses; Integration of provirus; APOBEC3G mediated resistance to HIV-1 infection; Calcineurin activates NFAT; Binding and entry of HIV virion; Assembly Of The HIV Virion; Uncoating of the HIV Virion; Minus-strand DNA synthesis; Plus-strand DNA synthesis"	"16"	"0"	"1265.5"	"6796.7"	"5588.7"	"777.3"	"4730.5"	"1569.9"	"2238.8"	"1718.5"	"2227.5"	"2792.3"	"5672.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11940"	"Polyadenylate-binding protein 1 OS=Homo sapiens OX=9606 GN=PABPC1 PE=1 SV=2"	"33"	"19"	"41"	"14"	"636"	"70.6"	"9.50"	"6429.20"	"63.14"	"16"	"19"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf00658"	"26986"	"ENSG00000070756"	"PABPC1"	"hsa:26986; P11940; Q15097; Q93004"	"Translation factors; Endoderm differentiation; VEGFA-VEGFR2 signaling; Acute viral myocarditis"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; AUF1 (hnRNP D0) binds and destabilizes mRNA; Regulation of expression of SLITs and ROBOs; Deadenylation of mRNA; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"11"	"5"	"1347.3"	"3217.4"	"3248.4"	"1337.2"	"3069.4"	"1542.0"	"3054.4"	"2402.4"	"3216.8"	"4052.0"	"5761.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63244"	"Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3"	"35"	"13"	"40"	"13"	"317"	"35.1"	"7.69"	"7136.59"	"63.02"	"12"	"13"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;cytosol;mitochondrion;translational apparatus;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;translation activity;other molecular function"	"Pf00400"	"10399"	"ENSG00000204628"	"RACK1"	"B3KTJ0; D3DWS0; hsa:10399; P25388; P63244; P99049; Q53HU2; Q5J8M6; Q5VLR4; Q6FH47"	"Androgen receptor signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; VEGFA-VEGFR2 signaling; Measles virus infection; Angiotensin II receptor type 1 pathway; TROP2 regulatory signaling; Interferon type I signaling pathways"	"Regulation of TNFR1 signaling; TNFR1-induced NF-kappa-B signaling pathway; TNFR1-mediated ceramide production"	"10"	"0"	"1065.8"	"3170.6"	"3104.8"	"1147.9"	"2674.9"	"1303.4"	"2698.2"	"1699.7"	"2571.8"	"3885.9"	"6276.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q05397"	"Focal adhesion kinase 1 OS=Homo sapiens OX=9606 GN=PTK2 PE=1 SV=2"	"16"	"15"	"35"	"15"	"1052"	"119.2"	"6.62"	"5993.24"	"62.87"	"12"	"14"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;kinase activity;other molecular function"	"Pf00373, Pf03623, Pf07714, Pf18038"	"5747"	"ENSG00000169398"	"PTK2"	"B4E2N6; F5H4S4; hsa:5747; J3QT16; Q05397; Q14291; Q8IYN9; Q9UD85"	"Androgen receptor signaling pathway; Integrin-mediated cell adhesion; RANKL/RANK signaling pathway; Leptin signaling pathway; Prolactin signaling pathway; Corticotropin-releasing hormone signaling pathway; Alpha 6 beta 4 signaling pathway; Primary focal segmental glomerulosclerosis (FSGS); Apoptosis-related network due to altered Notch3 in ovarian cancer; Focal adhesion; Hepatocyte growth factor receptor signaling; Overview of nanoparticle effects; MFAP5-mediated ovarian cancer cell motility and invasiveness; RAC1/PAK1/p38/MMP2 pathway; Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Prion disease pathway; PI3K-Akt signaling pathway; EGF/EGFR signaling pathway; Hippo-Merlin signaling dysregulation; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Small cell lung cancer; Gastrin signaling pathway; Netrin-UNC5B signaling pathway; Pleural mesothelioma; Regulation of actin cytoskeleton; 2q13 copy number variation syndrome; TROP2 regulatory signaling; A network map of Macrophage-stimulating protein (MSP) signaling; ErbB signaling pathway"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; EPHB-mediated forward signaling; Signal regulatory protein family interactions; DCC mediated attractive signaling; RAF/MAP kinase cascade; VEGFA-VEGFR2 Pathway; Estrogen-dependent nuclear events downstream of ESR-membrane signaling; NCAM signaling for neurite out-growth; MET activates PTK2 signaling; GRB2:SOS provides linkage to MAPK signaling for Integrins ; p130Cas linkage to MAPK signaling for integrins; Apoptotic cleavage of cellular proteins"	"48"	"0"	"372.1"	"814.9"	"859.2"	"359.3"	"902.2"	"450.0"	"1034.9"	"1769.3"	"4198.0"	"6471.4"	"9281.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q02878"	"60S ribosomal protein L6 OS=Homo sapiens OX=9606 GN=RPL6 PE=1 SV=3"	"42"	"15"	"42"	"15"	"288"	"32.7"	"10.58"	"7324.27"	"62.85"	"14"	"13"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01159, Pf03868"	"6128"	"ENSG00000089009"	"RPL6"	"hsa:6128; Q02878; Q2M3Q3; Q8WW97"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; SRP-dependent cotranslational protein targeting to membrane; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"1900.2"	"3575.4"	"3733.3"	"1624.6"	"3381.4"	"1766.8"	"8121.9"	"6065.7"	"7679.4"	"8681.9"	"11846.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23246"	"Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2"	"22"	"16"	"44"	"15"	"707"	"76.1"	"9.44"	"8833.76"	"62.70"	"16"	"14"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08075"	"6421"	"ENSG00000116560"	"SFPQ"	"hsa:6421; P23246; P30808; Q5SZ71"	"mRNA processing; Type 2 papillary renal cell carcinoma"	"Suppression of apoptosis; PTK6 Regulates Proteins Involved in RNA Processing"	"4"	"0"	"1272.5"	"1975.4"	"2112.0"	"1087.1"	"2107.6"	"1312.6"	"3370.8"	"2718.2"	"3836.6"	"4480.8"	"5765.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P27635"	"60S ribosomal protein L10 OS=Homo sapiens OX=9606 GN=RPL10 PE=1 SV=4"	"50"	"12"	"41"	"12"	"214"	"24.6"	"10.08"	"7306.46"	"62.40"	"8"	"10"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00252"	"100137264; 100146244; 100172946; 100415355; 100468790; 100724614; 100982236; 101083663; 101136536; 101344695; 101444008; 101539056; 101690567; 101867181; 101975002; 102028809; 102257301; 102442647; 102878669; 102890423; 102923570; 102957760; 103127392; 103211225; 103250904; 103731218; 104667036; 104872587; 105294701; 105302495; 105467951; 105521640; 105579731; 105727260; 105824536; 105867804; 106000161; 107160308; 108513162; 108518769; 109696857; 110954; 465944; 700795; 81764"	"ENSAMEG00000000227; ENSANAG00000036053; ENSCAFG00020009114; ENSCAFG00030015144; ENSCAFG00040021422; ENSCAFG00845028627; ENSCANG00000032226; ENSCATG00000030970; ENSCCAG00000024992; ENSCGRG00001008387; ENSCJAG00000011822; ENSCLAG00000003108; ENSCPOG00000002355; ENSECAG00000017154; ENSFCAG00000011395; ENSGGOG00000000131; ENSLCNG00005021252; ENSMFAG00000040824; ENSMLUG00000014337; ENSMMMG00000014279; ENSMMUG00000005494; ENSMNEG00000038094; ENSMPUG00000009320; ENSMUSG00000008682; ENSMUSG00000058443; ENSNGAG00000023746; ENSNLEG00000028143; ENSNVIG00000023818; ENSPANG00000008309; ENSPCOG00000027122; ENSPPAG00000034160; ENSPPYG00000020874; ENSPSMG00000015404; ENSPTIG00000005599; ENSPTRG00000043378; ENSRBIG00000042996; ENSRNOG00000056765; ENSRROG00000019247; ENSSSUG00005010590; ENSSTOG00000011857; ENSTGEG00000012563; ENSUAMG00000020454; ENSUMAG00000019583; ENSUPAG00010000252"	"LOC100768740; LOC101344695; LOC105294701; LOC112632580; Rpl10; RPL10"	"A0A091D943; A0A1S3APJ4; A0A1S3GPT7; A0A1U7SU42; A0A250YCK6; A0A286XQR8; A0A2I3FV08; A0A2J8IN69; A0A2J8RLU6; A0A2K5EV78; A0A2K5ILK8; A0A2K5LLF2; A0A2K5QER4; A0A2K5U275; A0A2K6D043; A0A2K6GRP4; A0A2K6MTH0; A0A2K6NK39; A0A2R9B361; A0A2Y9G5G6; A0A384DKX1; A0A3Q0CF07; A0A3Q7NJC4; A0A452S2Z9; A0A485PEW4; A0A667IJV2; A0A673U4F8; A0A6D2WIN2; A0A6D2XTB8; A0A6I9ME29; A0A6J0A9X4; A0A6J2E7G1; A0A6J3GU06; A0A6P3QFP2; A0A6P5P1X6; A0A6P6DLY1; A0A7J7YFN8; A0A7J8J7V5; A0A822A0T4; A0A8B7B976; A0A8B7FW91; A0A8C0K7J7; A0A8C0TBM4; A0A8C2LMI8; A0A8C2UVN1; A0A8C5ZPE8; A0A8C6S1T7; A0A8C7BXJ2; A0A8C8ZPD3; A0A8C9J452; A0A8D2F5T2; A0A8D2GF85; A0A8I3PXJ3; A0A8J8XDM4; A0A8M1M1S6; A0A9B0U593; A2AM97; A6KRS1; A9CB60; aju:106987320; aml:100468790; B0KWW6; B1MTV1; B3RFD9; C3PT02; cang:105521640; caty:105579731; ccan:109696857; cpoc:100724614; csyr:103250904; D3YC00; dnm:101444008; dord:106000161; ecb:100146244; F7AYR2; F7GKJ8; fca:101083663; G1PPT9; G2HFW2; G3S9Q9; G7Q3B3; ggo:101136536; H2PX84; I2CYS4; I3MI39; L5KDV0; L8Y8T7; M3WF14; M3YD39; mcal:110286529; mcc:700795; mcf:101867181; mlf:102442647; mmu:110954; mmur:105867804; mni:105467951; mpuf:101690567; myb:102257301; nsu:110578606; P45634; pale:102878669; pale:102890423; panu:100137264; pcoq:105824536; pps:100982236; ptg:102957760; ptr:465944; pvp:105294701; pvp:105302495; Q569M8; Q5M9K8; Q6PDV7; Q6ZWV3; rbb:108513162; rbb:108518769; rno:81764; rro:104667036; S7NR49; sara:101539056; tmu:101344695; umr:103679662; zca:113931110"	"Cytoplasmic ribosomal proteins"	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; SRP-dependent cotranslational protein targeting to membrane; Major pathway of rRNA processing in the nucleolus and cytosol; L13a-mediated translational silencing of Ceruloplasmin expression; SRP-dependent cotranslational protein targeting to membrane; Major pathway of rRNA processing in the nucleolus and cytosol; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	"15"	"0"	"1154.5"	"2351.0"	"2315.0"	"912.9"	"2351.0"	"1149.1"	"3489.2"	"2443.5"	"3162.7"	"4348.9"	"6158.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62753"	"40S ribosomal protein S6 OS=Homo sapiens OX=9606 GN=RPS6 PE=1 SV=1"	"38"	"14"	"37"	"14"	"249"	"28.7"	"10.84"	"5753.09"	"62.25"	"11"	"13"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01092"	"6194"	"ENSG00000137154"	"RPS6"	"hsa:6194; P08227; P10660; P62753; Q4VBY7; Q8N6Z7"	"IL-5 signaling pathway; Thyroid stimulating hormone (TSH) signaling pathway; Leptin signaling pathway; Follicle stimulating hormone (FSH) signaling pathway; Prolactin signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; Interleukin-11 signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Kit receptor signaling pathway; MECP2 and associated Rett syndrome; VEGFA-VEGFR2 signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Thermogenesis; Translation inhibitors in chronically activated PDGFRA cells; Gastrin signaling pathway; Head and neck squamous cell carcinoma; Thyroid hormones production and peripheral downstream signaling effects; Cytoplasmic ribosomal proteins; EGFR tyrosine kinase inhibitor resistance; IL-2 signaling pathway; Pleural mesothelioma; 2q37 copy number variation syndrome; A network map of Macrophage-stimulating protein (MSP) signaling; Interferon type I signaling pathways"	"Regulation of expression of SLITs and ROBOs; SRP-dependent cotranslational protein targeting to membrane; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; mTORC1-mediated signalling; Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol; SARS-CoV-2 modulates host translation machinery; Nuclear events stimulated by ALK signaling in cancer; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"47"	"0"	"1166.4"	"2029.7"	"2191.8"	"1007.9"	"2167.2"	"1285.6"	"3141.1"	"2483.9"	"3479.3"	"4185.5"	"5671.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49407"	"Beta-arrestin-1 OS=Homo sapiens OX=9606 GN=ARRB1 PE=1 SV=2"	"35"	"13"	"34"	"12"	"418"	"47.0"	"6.20"	"4834.72"	"61.05"	"10"	"13"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00339, Pf02752"	"408"	"ENSG00000137486"	"ARRB1"	"B6V9G8; hsa:408; O75625; O75630; P49407; Q2PP20; Q9BTK8"	"Corticotropin-releasing hormone signaling pathway; Myometrial relaxation and contraction pathways; MAPK signaling pathway; Chemokine signaling pathway; Hedgehog signaling pathway; Gastrin signaling pathway; Kisspeptin/kisspeptin receptor system in the ovary; GPR143 in melanocytes and retinal pigment epithelium cells; Calcium regulation in cardiac cells"	"Thrombin signalling through proteinase activated receptors (PARs); Ub-specific processing proteases; Activation of SMO; Activated NOTCH1 Transmits Signal to the Nucleus; G alpha (s) signalling events; Lysosome Vesicle Biogenesis; Golgi Associated Vesicle Biogenesis; Signaling by BRAF and RAF1 fusions; Cargo recognition for clathrin-mediated endocytosis; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants"	"25"	"1"	"178.4"	"308.8"	"424.8"	"180.1"	"369.2"	"273.7"	"634.5"	"926.6"	"2126.1"	"2927.2"	"4981.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16775"	"Hydroxyacylglutathione hydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=HAGH PE=1 SV=2"	"36"	"8"	"26"	"8"	"308"	"33.8"	"8.12"	"4562.15"	"60.74"	"5"	"8"	"other metabolic processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00753, Pf16123"	"3029"	"ENSG00000063854"	"HAGH"	"A8K290; B4DP33; B4DRA7; E7EN93; hsa:3029; Q16775"	""	""	"0"	"0"	"697.7"	"807.8"	"935.2"	"617.9"	"994.0"	"683.0"	"1200.8"	"933.4"	"1246.3"	"1517.6"	"1849.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06748"	"Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2"	"55"	"17"	"42"	"17"	"294"	"32.6"	"4.78"	"7946.56"	"60.34"	"15"	"16"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;translation activity;nucleic acid binding activity;other molecular function"	"Pf03066, Pf16276"	"4869"	"ENSG00000181163"	"NPM1"	"A8K3N7; B5BU00; D3DQL6; hsa:4869; P06748; P08693; Q12826; Q13440; Q13441; Q14115; Q5EU94; Q5EU95; Q5EU96; Q5EU97; Q5EU98; Q5EU99; Q6V962; Q8WTW5; Q96AT6; Q96DC4; Q96EA5; Q9BYG9; Q9UDJ7"	""	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain; Nuclear import of Rev protein; Deposition of new CENPA-containing nucleosomes at the centromere; SUMOylation of transcription cofactors; ALK mutants bind TKIs; Nuclear events stimulated by ALK signaling in cancer; TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation; SARS-CoV-1-host interactions"	"9"	"0"	"3367.7"	"5028.6"	"5833.1"	"2497.5"	"5047.1"	"3087.6"	"10084.3"	"7340.7"	"9806.2"	"11272.0"	"17307.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75390"	"Citrate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=CS PE=1 SV=2"	"23"	"11"	"34"	"11"	"466"	"51.7"	"8.32"	"6111.04"	"59.35"	"9"	"11"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00285"	"1431"	"ENSG00000062485"	"CS"	"hsa:1431; O75390; Q71UT9; Q7KZH0; Q96FZ8; Q9BWN8"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Fluoroacetic acid toxicity; TCA cycle (aka Krebs or citric acid cycle)"	"Mitochondrial protein import; Citric acid cycle (TCA cycle)"	"6"	"0"	"2362.3"	"3159.1"	"3210.4"	"2013.2"	"3196.8"	"2290.9"	"3224.2"	"2522.3"	"3127.7"	"3587.4"	"4591.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P12081"	"Histidine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=HARS1 PE=1 SV=2"	"32"	"17"	"33"	"17"	"509"	"57.4"	"5.88"	"4292.57"	"59.20"	"11"	"15"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00458, Pf03129, Pf13393"	"3035"	"ENSG00000170445"	"HARS1"	"B4DHQ1; B4DY73; D6REN6; hsa:3035; J3KNE5; P12081"	"Allograft rejection"	"Cytosolic tRNA aminoacylation"	"2"	"0"	"488.1"	"1009.5"	"1028.1"	"453.0"	"1009.3"	"606.9"	"1112.5"	"1135.9"	"2900.0"	"5407.5"	"10960.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61981"	"14-3-3 protein gamma OS=Homo sapiens OX=9606 GN=YWHAG PE=1 SV=2"	"36"	"10"	"35"	"4"	"247"	"28.3"	"4.89"	"6139.32"	"58.35"	"9"	"10"	"transport;signal transduction;other biological processes"	"cytosol;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00244"	"7532"	"ENSG00000170027"	"YWHAG"	"hsa:7532; O70457; P35214; P61981; Q6FH52; Q9UDP2; Q9UN99"	"Cell cycle; Prolactin signaling pathway; Myometrial relaxation and contraction pathways; Disruption of postsynaptic signaling by CNV; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Regulation of localization of FOXO transcription factors; TP53 Regulates Metabolic Genes; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Activation of BAD and translocation to mitochondria"	"21"	"0"	"159.2"	"354.2"	"342.4"	"144.5"	"328.7"	"182.9"	"304.2"	"261.3"	"407.2"	"412.0"	"718.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13647"	"Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3"	"20"	"16"	"40"	"6"	"590"	"62.3"	"7.74"	"5755.93"	"58.23"	"14"	"16"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;other cell component"	"bone, tooth or skin structural activity;cytoskeletal activity;other molecular function"	"Pf00038, Pf16208"	"3852"	"ENSG00000186081"	"KRT5"	"hsa:3852; P13647; Q6PI71; Q6UBJ0; Q8TA91"	""	"Formation of the cornified envelope; Type I hemidesmosome assembly"	"3"	"0"	"289.9"	"755.9"	"7206.7"	"174.5"	"90.9"	"285.7"	"429.5"	"670.4"	"621.5"	"636.7"	"726.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61158"	"Actin-related protein 3 OS=Homo sapiens OX=9606 GN=ACTR3 PE=1 SV=3"	"34"	"11"	"24"	"9"	"418"	"47.3"	"5.88"	"3867.68"	"56.54"	"7"	"11"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00022"	"10096"	"ENSG00000115091"	"ACTR3"	"hsa:10096; P32391; P61158; Q53QM2"	"Physico-chemical features and toxicity-associated pathways"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; EPHB-mediated forward signaling; Clathrin-mediated endocytosis"	"6"	"2"	"355.3"	"643.2"	"711.9"	"333.6"	"675.2"	"415.4"	"1373.9"	"1599.0"	"2194.8"	"4003.6"	"9413.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P53621"	"Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2"	"14"	"16"	"34"	"16"	"1224"	"138.3"	"7.66"	"5580.53"	"56.41"	"14"	"15"	"transport;signal transduction"	"non-structural extracellular;other membranes;cytosol;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00400, Pf04053, Pf06957, Pf12894"	"1314"	"ENSG00000122218"	"COPA"	"hsa:1314; P53621; Q5T201; Q8IXZ9"	""	"COPI-mediated anterograde transport; COPI-dependent Golgi-to-ER retrograde traffic"	"2"	"0"	"739.2"	"1388.9"	"1478.6"	"587.5"	"1339.5"	"721.2"	"1357.1"	"1049.7"	"1422.9"	"2054.8"	"3009.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46109"	"Crk-like protein OS=Homo sapiens OX=9606 GN=CRKL PE=1 SV=1"	"44"	"11"	"32"	"11"	"303"	"33.8"	"6.74"	"5325.12"	"55.74"	"10"	"10"	"cell-cell signaling;cell organization and biogenesis;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00017, Pf00018, Pf07653"	"1399"	"ENSG00000099942"	"CRKL"	"A8KA44; D3DX35; hsa:1399; P46109"	"Androgen receptor network in prostate cancer; B cell receptor signaling pathway; IL-3 signaling pathway; Kit receptor signaling pathway; Focal adhesion; Hepatocyte growth factor receptor signaling; MAPK signaling pathway; Chemokine signaling pathway; EGF/EGFR signaling pathway; 22q11.2 copy number variation syndrome; IL-2 signaling pathway; A network map of Macrophage-stimulating protein (MSP) signaling; Interferon type I signaling pathways; ErbB signaling pathway; T-cell receptor signaling pathway"	"Regulation of signaling by CBL; Downstream signal transduction; Erythropoietin activates RAS; Frs2-mediated activation; MET activates RAP1 and RAC1; MET receptor recycling"	"21"	"0"	"810.3"	"978.4"	"1050.7"	"559.4"	"992.0"	"664.1"	"978.3"	"702.1"	"978.3"	"1217.9"	"1570.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14103"	"Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1"	"34"	"14"	"37"	"11"	"355"	"38.4"	"7.81"	"6157.61"	"55.37"	"12"	"12"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08143"	"3184"	"ENSG00000138668"	"HNRNPD"	"A8K9J2; hsa:3184; P07029; Q01858; Q14100; Q14101; Q14102; Q14103; Q4W5A1; Q9UCE8; Q9UCE9"	"mRNA processing"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"3"	"5"	"1285.3"	"2787.0"	"2789.3"	"1146.4"	"2533.3"	"1393.3"	"2590.5"	"1784.1"	"2519.0"	"2776.8"	"4068.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08559"	"Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial OS=Homo sapiens OX=9606 GN=PDHA1 PE=1 SV=3"	"33"	"16"	"42"	"16"	"390"	"43.3"	"8.06"	"7847.30"	"55.19"	"13"	"16"	"other metabolic processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00676"	"5160"	"ENSG00000131828"	"PDHA1"	"A5YVE9; B2R5P7; B7Z3T7; B7Z3X5; hsa:5160; P08559; Q53H41; Q5JPT8; Q9NP12; Q9UBJ8; Q9UBU0; Q9UNG4; Q9UNG5"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Lipid metabolism pathway; PI3K/AKT/mTOR - vitamin D3 signaling; Metabolic reprogramming in colon cancer; Thiamine metabolic pathways; TCA cycle in senescence; Neuroinflammation and glutamatergic signaling; Acetylcholine synthesis; Glycolysis and gluconeogenesis"	"Glyoxylate metabolism and glycine degradation; Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid"	"14"	"0"	"2234.8"	"4570.0"	"4625.0"	"2478.5"	"4076.5"	"2640.1"	"4314.7"	"3768.2"	"4563.2"	"5156.9"	"6221.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95602"	"DNA-directed RNA polymerase I subunit RPA1 OS=Homo sapiens OX=9606 GN=POLR1A PE=1 SV=2"	"13"	"16"	"29"	"16"	"1720"	"194.7"	"7.03"	"4648.79"	"55.10"	"11"	"15"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00623, Pf04983, Pf04997, Pf04998, Pf05000"	"25885"	"ENSG00000068654"	"POLR1A"	"B7Z7T0; D6W5M0; hsa:25885; O95602; Q0VG05; Q9UEH0; Q9UFT9"	"Pyrimidine metabolism; Eukaryotic transcription initiation; 2q13 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"8"	"0"	"302.6"	"634.6"	"646.0"	"283.6"	"656.6"	"342.0"	"711.8"	"1105.8"	"2794.1"	"4416.6"	"5274.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08708"	"40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2"	"56"	"6"	"17"	"6"	"135"	"15.5"	"9.85"	"1072.39"	"55.04"	"3"	"6"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00833"	"6218"	"ENSG00000182774; ENSG00000278229"	"RPS17"	"B2R4U4; hsa:6218; P08708; P0CW22"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"272.2"	"565.6"	"560.1"	"254.0"	"514.7"	"296.5"	"758.4"	"749.6"	"919.3"	"1131.1"	"1538.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61221"	"ATP-binding cassette sub-family E member 1 OS=Homo sapiens OX=9606 GN=ABCE1 PE=1 SV=1"	"24"	"13"	"26"	"13"	"599"	"67.3"	"8.34"	"3824.98"	"54.50"	"10"	"13"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;mitochondrion;translational apparatus;other cell component"	"enzyme regulator activity;translation activity;other molecular function"	"Pf00005, Pf00037, Pf04068"	"6059"	"ENSG00000164163"	"ABCE1"	"hsa:6059; O88793; P61221; Q13181; Q13864; Q6NR76; Q96AL0; Q96B10; Q99K66"	""	"OAS antiviral response; Interferon alpha/beta signaling"	"2"	"0"	"418.3"	"892.3"	"1000.2"	"372.7"	"936.3"	"467.4"	"1813.1"	"1469.5"	"2248.6"	"3872.5"	"6927.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P27695"	"DNA-(apurinic or apyrimidinic site) lyase OS=Homo sapiens OX=9606 GN=APEX1 PE=1 SV=2"	"41"	"11"	"28"	"11"	"318"	"35.5"	"8.12"	"6140.67"	"54.24"	"11"	"10"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytoskeleton;mitochondrion;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03372"	"328"	"ENSG00000100823"	"APEX1"	"hsa:328; P27695; Q969L5; Q99775"	"Thyroid stimulating hormone (TSH) signaling pathway; Spinal cord injury; Base excision repair; DNA repair pathways, full network"	"Displacement of DNA glycosylase by APEX1; POLB-Dependent Long Patch Base Excision Repair; PCNA-Dependent Long Patch Base Excision Repair; Abasic sugar-phosphate removal via the single-nucleotide replacement pathway"	"10"	"0"	"379.1"	"770.1"	"840.9"	"327.9"	"776.7"	"400.3"	"2478.0"	"1997.8"	"2712.0"	"3307.5"	"4879.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62269"	"40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3"	"45"	"10"	"34"	"10"	"152"	"17.7"	"10.99"	"6582.75"	"54.22"	"10"	"8"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00416"	"6222"	"ENSG00000096150; ENSG00000223367; ENSG00000226225; ENSG00000231500; ENSG00000235650"	"RPS18"	"hsa:6222; P25232; P62269; Q5SUJ3; Q6IPF8"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"1286.9"	"2929.5"	"2858.8"	"1312.4"	"2521.9"	"1324.4"	"3346.1"	"2539.1"	"3521.4"	"4571.9"	"6689.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NTJ3"	"Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2"	"16"	"17"	"28"	"17"	"1288"	"147.1"	"6.79"	"3920.31"	"54.07"	"11"	"15"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02463, Pf06470"	"10051"	"ENSG00000113810"	"SMC4"	"A6NLT9; D3DNL8; hsa:10051; O95752; Q8NDL4; Q9NTJ3; Q9UNT9"	"Ciliary landscape"	"Condensation of Prophase Chromosomes; Condensation of Prometaphase Chromosomes"	"3"	"0"	"488.3"	"987.3"	"1131.5"	"446.4"	"1017.0"	"604.3"	"1714.3"	"1394.8"	"1961.6"	"2958.1"	"4259.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43175"	"D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4"	"30"	"12"	"30"	"12"	"533"	"56.6"	"6.71"	"5624.58"	"53.97"	"9"	"11"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;developmental processes;other biological processes"	"cytosol"	"other molecular function"	"Pf00389, Pf02826, Pf19304"	"26227"	"ENSG00000092621"	"PHGDH"	"B2RD08; hsa:26227; O43175; Q5SZU3; Q9BQ01"	"Trans-sulfuration, one-carbon metabolism and related pathways; Clear cell renal cell carcinoma pathways; Neuroinflammation and glutamatergic signaling; Amino acid metabolism in triple-negative breast cancer cells"	"Serine biosynthesis"	"5"	"0"	"931.1"	"4521.9"	"3708.7"	"680.4"	"3024.2"	"1122.9"	"1391.1"	"1014.6"	"1502.6"	"2000.4"	"3752.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05388"	"60S acidic ribosomal protein P0 OS=Homo sapiens OX=9606 GN=RPLP0 PE=1 SV=1"	"42"	"12"	"27"	"12"	"317"	"34.3"	"5.97"	"4736.96"	"53.51"	"10"	"11"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00428, Pf00466, Pf17777"	"6175"	"ENSG00000089157"	"RPLP0"	"hsa:6175; P05388; Q3B7A4; Q9BVK4"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"15"	"0"	"689.6"	"1828.5"	"1700.0"	"721.4"	"1561.4"	"794.7"	"2196.9"	"1594.2"	"1955.3"	"2367.3"	"3713.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62081"	"40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1"	"63"	"14"	"26"	"14"	"194"	"22.1"	"10.10"	"3918.05"	"53.05"	"9"	"12"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf01251"	"6201"	"ENSG00000171863"	"RPS7"	"hsa:6201; P23821; P24818; P62081; Q57Z92; Q6IPH1"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"20"	"0"	"1010.6"	"2379.1"	"2303.5"	"1007.9"	"2101.1"	"992.2"	"2109.7"	"1592.4"	"2322.4"	"3329.4"	"5291.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P26639"	"Threonine--tRNA ligase 1, cytoplasmic OS=Homo sapiens OX=9606 GN=TARS1 PE=1 SV=3"	"24"	"16"	"29"	"16"	"723"	"83.4"	"6.67"	"3135.28"	"53.03"	"9"	"15"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol"	"nucleic acid binding activity;other molecular function"	"Pf00587, Pf02824, Pf03129, Pf07973"	"6897"	"ENSG00000113407"	"TARS1"	"A8K8I1; B4DEG8; hsa:6897; P26639; Q96FP5; Q9BWA6"	""	"Cytosolic tRNA aminoacylation"	"1"	"0"	"470.9"	"808.6"	"1015.8"	"409.6"	"1054.0"	"573.7"	"2007.8"	"1547.4"	"2398.8"	"4097.0"	"10468.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q07666"	"KH domain-containing, RNA-binding, signal transduction-associated protein 1 OS=Homo sapiens OX=9606 GN=KHDRBS1 PE=1 SV=1"	"23"	"12"	"31"	"12"	"443"	"48.2"	"8.66"	"6011.55"	"52.89"	"10"	"11"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf16274, Pf16568"	"10657"	"ENSG00000121774"	"KHDRBS1"	"D3DPP3; hsa:10657; Q07666; Q6PJX7; Q8NB97; Q99760"	"Leptin signaling pathway; Primary ovarian insufficiency"	"PTK6 Regulates Proteins Involved in RNA Processing"	"3"	"0"	"937.6"	"1728.5"	"1834.4"	"825.5"	"1562.4"	"904.0"	"2827.3"	"2138.9"	"3273.6"	"3804.7"	"5319.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31948"	"Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1"	"34"	"17"	"35"	"17"	"543"	"62.6"	"6.80"	"6276.72"	"52.83"	"15"	"17"	"other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00515, Pf13181, Pf17830"	"10963"	"ENSG00000168439"	"STIP1"	"B4DM70; F5H0T1; G3XAD8; hsa:10963; P31948; Q3ZCU9; Q5TZU9"	"VEGFA-VEGFR2 signaling"	"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; RND1 GTPase cycle"	"3"	"0"	"1253.1"	"4763.8"	"4036.0"	"1020.3"	"3519.8"	"1439.4"	"1854.0"	"1511.8"	"2223.5"	"2795.1"	"5163.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99623"	"Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2"	"37"	"10"	"32"	"10"	"299"	"33.3"	"9.83"	"5564.74"	"52.73"	"9"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01145"	"11331"	"ENSG00000215021"	"PHB2"	"B4DP75; hsa:11331; Q2YDA4; Q7KYU3; Q92978; Q99623"	""	"Processing of SMDT1"	"1"	"0"	"993.0"	"2449.5"	"2730.5"	"882.7"	"2493.8"	"1160.5"	"2134.9"	"1503.6"	"2290.6"	"3207.2"	"5085.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P12277"	"Creatine kinase B-type OS=Homo sapiens OX=9606 GN=CKB PE=1 SV=1"	"32"	"10"	"24"	"10"	"381"	"42.6"	"5.59"	"3453.20"	"52.61"	"7"	"9"	"other metabolic processes;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00217, Pf02807"	"1152"	"ENSG00000166165"	"CKB"	"A8K236; B2R5R4; hsa:1152; P12277; Q2LE07; Q6FG40; Q9UC66"	""	"RND3 GTPase cycle; Creatine metabolism"	"2"	"0"	"342.9"	"3230.9"	"2436.0"	"194.7"	"2041.6"	"498.9"	"844.6"	"641.5"	"907.1"	"1120.7"	"2654.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62906"	"60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2"	"41"	"12"	"38"	"12"	"217"	"24.8"	"9.94"	"8302.36"	"52.40"	"10"	"11"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf00687"	"4736"	"ENSG00000198755"	"RPL10A"	"B2R801; hsa:4736; P52859; P53025; P62906; Q5TZT6; Q8J013"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; SRP-dependent cotranslational protein targeting to membrane; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"15"	"0"	"617.7"	"1571.5"	"1526.4"	"556.0"	"1363.2"	"619.8"	"2185.8"	"1696.8"	"2334.6"	"2939.9"	"4517.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P34897"	"Serine hydroxymethyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=SHMT2 PE=1 SV=3"	"33"	"16"	"33"	"15"	"504"	"56.0"	"8.53"	"5598.13"	"51.94"	"14"	"14"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00464"	"6472"	"ENSG00000182199"	"SHMT2"	"B7Z9F1; E7EQ19; E7EU43; hsa:6472; O00740; P34897; Q8N1A5"	"Glycine metabolism; Vitamin B12 metabolism; Folate metabolism; One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Neuroinflammation and glutamatergic signaling"	"RHOG GTPase cycle; Metabolism of folate and pterines"	"10"	"1"	"723.5"	"2865.9"	"2274.5"	"537.8"	"2188.5"	"781.6"	"1386.1"	"1026.4"	"1291.0"	"1601.9"	"2869.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3I0"	"RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1"	"31"	"14"	"26"	"14"	"505"	"55.2"	"7.23"	"3238.39"	"51.55"	"8"	"12"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01139"	"51493"	"ENSG00000100220"	"RTCB"	"B2R6A8; hsa:51493; Q6IAI0; Q9BWL4; Q9NTH1; Q9P037; Q9P0J3; Q9Y3I0"	"Unfolded protein response"	"tRNA processing in the nucleus"	"2"	"0"	"980.5"	"1647.3"	"1794.5"	"861.3"	"1724.4"	"1068.8"	"2289.5"	"1693.2"	"2554.7"	"3303.9"	"4885.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q00610"	"Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5"	"10"	"15"	"34"	"15"	"1675"	"191.5"	"5.69"	"5218.50"	"50.97"	"13"	"15"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00637, Pf01394, Pf09268, Pf13838"	"1213"	"ENSG00000141367"	"CLTC"	"D3DU00; hsa:1213; Q00610; Q6N0A0; Q86TF2"	"Synaptic vesicle pathway; VEGFA-VEGFR2 signaling; Ebola virus infection in host; Fragile X syndrome; 7q11.23 copy number variation syndrome; Complement and coagulation cascades"	"Recycling pathway of L1; MHC class II antigen presentation; ALK mutants bind TKIs; Nuclear events stimulated by ALK signaling in cancer; RHOV GTPase cycle; Lysosome Vesicle Biogenesis; RHOU GTPase cycle; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; LDL clearance; Retrograde neurotrophin signalling; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; VLDLR internalisation and degradation; Entry of Influenza Virion into Host Cell via Endocytosis; Formation of annular gap junctions"	"25"	"0"	"876.8"	"2131.7"	"2052.2"	"796.9"	"1857.0"	"1088.0"	"1229.0"	"888.2"	"1255.8"	"1660.0"	"2649.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P16989"	"Y-box-binding protein 3 OS=Homo sapiens OX=9606 GN=YBX3 PE=1 SV=4"	"32"	"8"	"22"	"5"	"372"	"40.1"	"9.77"	"3291.23"	"50.93"	"7"	"8"	"stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00313"	"8531"	"ENSG00000060138"	"YBX3"	"B2RBW6; hsa:8531; P16989; Q14121; Q969N6; Q96B76"	"RalA downstream regulated genes; Apoptosis-related network due to altered Notch3 in ovarian cancer"	""	"2"	"0"	"147.8"	"254.7"	"253.5"	"140.1"	"274.7"	"161.7"	"304.1"	"246.7"	"320.4"	"350.9"	"453.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5JRX3"	"Presequence protease, mitochondrial OS=Homo sapiens OX=9606 GN=PITRM1 PE=1 SV=3"	"17"	"14"	"24"	"14"	"1037"	"117.3"	"6.92"	"2460.36"	"50.88"	"8"	"13"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport"	"mitochondrion"	"enzyme regulator activity;other molecular function"	"Pf00675, Pf05193, Pf08367"	"10531"	"ENSG00000107959"	"PITRM1"	"B3KMJ6; B4E0J8; C9JSL2; E7ES23; hsa:10531; O95204; Q2M2G6; Q4VBR1; Q5JRW7; Q5JRX3; Q7L5Z7; Q9BSI6; Q9BVJ5; Q9UPP8"	""	"Mitochondrial protein import"	"1"	"0"	"375.2"	"830.4"	"878.2"	"319.0"	"808.7"	"403.6"	"745.5"	"643.6"	"1102.4"	"2917.8"	"9888.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q05639"	"Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1"	"22"	"10"	"32"	"1"	"463"	"50.4"	"9.03"	"5068.84"	"50.40"	"9"	"10"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03143, Pf03144"	"1917"	"ENSG00000101210"	"EEF1A2"	"B5BUF3; E1P5J1; hsa:1917; P54266; Q05639; Q0VGC7"	"Translation factors"	"Eukaryotic Translation Elongation"	"2"	"0"	"80.7"	"161.4"	"166.9"	"76.4"	"142.8"	"91.7"	"186.8"	"140.2"	"186.7"	"285.3"	"562.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49321"	"Nuclear autoantigenic sperm protein OS=Homo sapiens OX=9606 GN=NASP PE=1 SV=2"	"17"	"12"	"28"	"12"	"788"	"85.2"	"4.30"	"4518.24"	"50.19"	"11"	"12"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf10516"	"4678"	"ENSG00000132780"	"NASP"	"A8K6H2; B4DQP3; D3DQ07; F5H3J2; hsa:4678; P49321; Q53GW5; Q5T622; Q5T625; Q96A69; Q9BTW2"	""	""	"0"	"0"	"1688.0"	"3994.3"	"3978.4"	"1380.1"	"3658.9"	"1881.2"	"2448.5"	"1865.8"	"2626.8"	"3082.0"	"5271.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P39019"	"40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2"	"59"	"11"	"28"	"11"	"145"	"16.1"	"10.32"	"5530.58"	"50.08"	"10"	"11"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01090"	"6223"	"ENSG00000105372"	"RPS19"	"hsa:6223; P39019"	"Complement system; Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"20"	"0"	"910.2"	"1733.6"	"1781.7"	"768.6"	"1673.5"	"916.2"	"2783.0"	"2185.7"	"2995.1"	"3603.0"	"4896.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P83731"	"60S ribosomal protein L24 OS=Homo sapiens OX=9606 GN=RPL24 PE=1 SV=1"	"46"	"11"	"34"	"11"	"157"	"17.8"	"11.25"	"7271.95"	"50.04"	"10"	"7"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01246"	"6152"	"ENSG00000114391"	"RPL24"	"B2R4Y3; hsa:6152; P38663; P83731; Q6IBS3"	"Cytoplasmic ribosomal proteins"	"Major pathway of rRNA processing in the nucleolus and cytosol; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"1409.8"	"2605.9"	"2672.3"	"1198.1"	"2581.8"	"1367.2"	"4675.2"	"3516.6"	"4547.0"	"5470.9"	"7648.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11586"	"C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=3"	"21"	"18"	"36"	"18"	"935"	"101.5"	"7.30"	"6734.85"	"49.70"	"17"	"15"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"813.2"	"2343.2"	"2012.4"	"577.0"	"1809.1"	"933.6"	"1703.7"	"1348.4"	"1652.0"	"2463.6"	"3550.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13428"	"Treacle protein OS=Homo sapiens OX=9606 GN=TCOF1 PE=1 SV=3"	"12"	"18"	"36"	"18"	"1488"	"152.0"	"9.04"	"7398.69"	"49.39"	"18"	"14"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf03546"	"6949"	"ENSG00000070814"	"TCOF1"	"A0JLU0; B4E111; hsa:6949; Q13428; Q6SC72; Q7Z5W9; Q96A52; Q99408; Q99860"	""	""	"0"	"0"	"1367.5"	"2287.9"	"2546.3"	"1073.7"	"2406.5"	"1970.3"	"7465.8"	"3697.7"	"4366.2"	"4917.8"	"6729.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49207"	"60S ribosomal protein L34 OS=Homo sapiens OX=9606 GN=RPL34 PE=1 SV=3"	"46"	"11"	"29"	"11"	"117"	"13.3"	"11.47"	"4356.35"	"49.39"	"9"	"11"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01199"	"6164"	"ENSG00000109475"	"RPL34"	"hsa:6164; P49207; Q6FG66; Q9BUZ2"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"1165.8"	"2211.6"	"2431.4"	"961.5"	"2375.8"	"1202.5"	"3898.7"	"3015.7"	"3789.3"	"4754.8"	"6677.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62263"	"40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3"	"42"	"8"	"23"	"8"	"151"	"16.3"	"10.05"	"3393.83"	"49.19"	"6"	"8"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00411"	"6208"	"ENSG00000164587"	"RPS14"	"B2R5G5; D3DQG5; hsa:6208; P06366; P62263; Q5BJI0"	"Cytoplasmic ribosomal proteins"	"Major pathway of rRNA processing in the nucleolus and cytosol; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); rRNA modification in the nucleus and cytosol; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"20"	"0"	"368.2"	"678.3"	"743.3"	"305.5"	"758.2"	"373.8"	"1016.5"	"769.9"	"1030.2"	"1319.1"	"1851.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P48643"	"T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1"	"28"	"15"	"31"	"15"	"541"	"59.6"	"5.66"	"6348.15"	"49.16"	"13"	"14"	"transport;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00118"	"22948"	"ENSG00000150753"	"CCT5"	"A8JZY8; A8K2X8; B4DYD8; hsa:22948; P48643"	"16p11.2 proximal deletion syndrome"	"Prefoldin mediated transfer of substrate  to CCT/TriC; Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Folding of actin by CCT/TriC"	"7"	"0"	"1225.7"	"3295.1"	"3578.5"	"1016.8"	"2819.0"	"1350.5"	"1975.7"	"1507.7"	"2159.3"	"2874.3"	"4674.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60174"	"Triosephosphate isomerase OS=Homo sapiens OX=9606 GN=TPI1 PE=1 SV=3"	"44"	"11"	"29"	"11"	"286"	"30.8"	"5.92"	"5383.42"	"49.13"	"10"	"11"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf00121"	""	"ENSPPYG00000004207; ENSPTRG00000004595"	"TPI1"	"A0A2J8JEI5; A0A2J8JEJ3; A0A2J8TBG7; A0A6D2X563; H2NGA4"	""	""	"0"	"0"	"643.1"	"6062.7"	"5183.9"	"214.6"	"4614.2"	"1087.5"	"1412.0"	"815.7"	"1158.7"	"1381.7"	"3874.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3A5"	"Ribosome maturation protein SBDS OS=Homo sapiens OX=9606 GN=SBDS PE=1 SV=4"	"54"	"13"	"23"	"13"	"250"	"28.7"	"8.75"	"3594.92"	"48.87"	"7"	"11"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;translation activity;nucleic acid binding activity"	"Pf01172, Pf09377, Pf20268"	"51119"	"ENSG00000126524"	"SBDS"	"A8K0P4; hsa:51119; Q96FX0; Q9NV53; Q9Y3A5"	"Genetic causes of porto-sinusoidal vascular disease"	""	"1"	"0"	"316.0"	"713.9"	"713.0"	"318.7"	"724.4"	"362.6"	"1471.5"	"1453.0"	"2402.8"	"4946.7"	"10223.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49368"	"T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4"	"36"	"18"	"31"	"18"	"545"	"60.5"	"6.49"	"5608.71"	"48.78"	"15"	"14"	"cell organization and biogenesis;transport;other biological processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00118"	"7203"	"ENSG00000163468"	"CCT3"	"A6NE14; hsa:7203; P49368; Q5SZY1; Q9BR64"	"16p11.2 proximal deletion syndrome"	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Association of TriC/CCT with target proteins during biosynthesis; Prefoldin mediated transfer of substrate  to CCT/TriC; Folding of actin by CCT/TriC"	"7"	"0"	"1141.6"	"2860.6"	"2822.3"	"924.3"	"2269.8"	"1088.9"	"1536.4"	"1193.4"	"1732.3"	"2156.9"	"3517.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06454"	"Prothymosin alpha OS=Homo sapiens OX=9606 GN=PTMA PE=1 SV=2"	"23"	"5"	"22"	"5"	"111"	"12.2"	"3.78"	"6125.11"	"48.55"	"5"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf03247"	"5757"	"ENSG00000187514"	"PTMA"	"hsa:5757; P06454; Q15249; Q15592"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"286.1"	"2095.7"	"1351.5"	"141.1"	"1064.7"	"350.4"	"597.0"	"516.4"	"587.8"	"663.1"	"1569.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P18621"	"60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3"	"47"	"10"	"31"	"10"	"184"	"21.4"	"10.17"	"5380.00"	"48.13"	"10"	"9"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf00237"	"6139"	"ENSG00000265681"	"RPL17"	"B2R4H3; B4E3C2; B5ME31; hsa:6139; J3QL51; P18621; Q3KQW2; Q6NZ54; Q7M4M5"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"1041.4"	"2034.9"	"2309.3"	"892.7"	"2064.6"	"1023.9"	"3811.7"	"2537.5"	"3607.7"	"4249.5"	"6089.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60506"	"Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2"	"29"	"15"	"30"	"9"	"623"	"69.6"	"8.59"	"5013.36"	"48.12"	"13"	"13"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf18360"	"10492"	"ENSG00000135316"	"SYNCRIP"	"E1P501; E1P502; hsa:10492; O60506; Q53H05; Q5TCG2; Q5TCG3; Q8IW78; Q8N599; Q96LC1; Q96LC2; Q9Y583"	""	""	"0"	"6"	"1036.2"	"2401.5"	"2325.7"	"889.4"	"2253.2"	"1145.1"	"1978.9"	"1345.0"	"2021.8"	"2474.7"	"3753.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62241"	"40S ribosomal protein S8 OS=Homo sapiens OX=9606 GN=RPS8 PE=1 SV=2"	"53"	"11"	"31"	"11"	"208"	"24.2"	"10.32"	"4032.10"	"48.00"	"8"	"11"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01201"	"6202"	"ENSG00000142937"	"RPS8"	"hsa:6202; P09058; P62241; Q6IRL7"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Selenocysteine synthesis; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"720.6"	"1467.7"	"1372.9"	"651.1"	"1297.6"	"753.9"	"2170.8"	"1956.5"	"2401.7"	"2990.3"	"3844.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46782"	"40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4"	"43"	"10"	"27"	"10"	"204"	"22.9"	"9.72"	"5227.12"	"47.58"	"10"	"9"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00177"	"6193"	"ENSG00000083845"	"RPS5"	"B2R4T2; hsa:6193; P46782; Q96BN0"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Peptide chain elongation; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"542.1"	"1142.6"	"1053.1"	"445.5"	"1061.9"	"597.9"	"1468.4"	"1198.0"	"1697.0"	"2325.1"	"3239.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08779"	"Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4"	"29"	"16"	"33"	"9"	"473"	"51.2"	"5.05"	"6062.87"	"47.03"	"14"	"14"	"cell organization and biogenesis;stress response;other biological processes"	"plasma membrane;cytosol;cytoskeleton"	"cytoskeletal activity"	"Pf00038"	"3868"	"ENSG00000186832"	"KRT16"	"A8K488; hsa:3868; P08779; P30654; Q16402; Q9UBG8"	"Vitamin D receptor pathway"	"Formation of the cornified envelope"	"3"	"2"	"329.4"	"856.9"	"12880.4"	"262.2"	"245.1"	"359.4"	"654.0"	"497.0"	"760.5"	"1039.3"	"1091.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P40227"	"T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3"	"28"	"12"	"27"	"12"	"531"	"58.0"	"6.68"	"4698.80"	"46.94"	"10"	"9"	"other biological processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00118"	"908"	"ENSG00000146731"	"CCT6A"	"A6NCD2; hsa:908; P40227; Q3KP28; Q75LP4; Q96S46"	"16p11.2 proximal deletion syndrome"	"Formation of tubulin folding intermediates by CCT/TriC; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; RHOBTB2 GTPase cycle; Folding of actin by CCT/TriC"	"7"	"0"	"1000.5"	"2720.3"	"2589.6"	"779.8"	"2018.8"	"966.4"	"1346.2"	"1144.4"	"1559.0"	"2139.7"	"3643.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P32969"	"60S ribosomal protein L9 OS=Homo sapiens OX=9606 GN=RPL9 PE=1 SV=1"	"52"	"9"	"27"	"9"	"192"	"21.9"	"9.95"	"5128.24"	"46.49"	"7"	"8"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00347"	"6133"	"ENSG00000163682"	"RPL9; RPL9P7; RPL9P8; RPL9P9"	"hsa:6133; P32969"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis"	"14"	"0"	"343.6"	"903.7"	"823.1"	"334.3"	"710.0"	"372.2"	"1083.3"	"1069.6"	"1302.3"	"1712.1"	"2495.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14697"	"Neutral alpha-glucosidase AB OS=Homo sapiens OX=9606 GN=GANAB PE=1 SV=3"	"17"	"13"	"23"	"13"	"944"	"106.8"	"6.14"	"2791.83"	"46.22"	"8"	"13"	"protein metabolism;other metabolic processes"	"ER/Golgi;other cell component"	"other molecular function"	"Pf01055, Pf13802"	"23193"	"ENSG00000089597"	"GANAB"	"A6NC20; hsa:23193; Q14697; Q8WTS9; Q9P0X0"	"N-glycan biosynthesis"	"Maturation of spike protein; Calnexin/calreticulin cycle; Maturation of spike protein"	"5"	"0"	"485.4"	"1274.1"	"1271.9"	"399.6"	"1210.4"	"549.5"	"820.5"	"682.1"	"1035.8"	"1588.4"	"2492.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43684"	"Mitotic checkpoint protein BUB3 OS=Homo sapiens OX=9606 GN=BUB3 PE=1 SV=1"	"32"	"11"	"30"	"11"	"328"	"37.1"	"6.84"	"5376.27"	"45.99"	"11"	"10"	"cell cycle OR cell proliferation;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00400"	"9184"	"ENSG00000154473"	"BUB3"	"A6NJ42; B2R6E7; D3DRE9; hsa:9184; O43684; O43685"	"Cell cycle; Regulation of sister chromatid separation at the metaphase-anaphase transition"	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of mitotic proteins; APC-Cdc20 mediated degradation of Nek2A"	"12"	"0"	"980.8"	"1586.1"	"1527.9"	"803.0"	"1490.0"	"865.4"	"1651.2"	"1847.5"	"2305.9"	"3413.4"	"6971.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P26358"	"DNA (cytosine-5)-methyltransferase 1 OS=Homo sapiens OX=9606 GN=DNMT1 PE=1 SV=2"	"9"	"13"	"29"	"13"	"1616"	"183.1"	"7.75"	"5325.52"	"45.66"	"13"	"12"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00145, Pf01426, Pf02008, Pf06464, Pf12047"	"1786"	"ENSG00000130816"	"DNMT1"	"A0AV63; B7ZLW6; hsa:1786; P26358; Q9UHG5; Q9ULA2; Q9UMZ6"	"Trans-sulfuration pathway; One-carbon metabolism; Retinoblastoma gene in cancer; Hematopoietic stem cell gene regulation by GABP alpha/beta complex; MTHFR deficiency"	"SUMOylation of DNA methylation proteins; NoRC negatively regulates rRNA expression; PRC2 methylates histones and DNA; Defective pyroptosis; DNA methylation"	"10"	"0"	"560.8"	"850.6"	"920.7"	"491.1"	"894.5"	"580.6"	"1528.8"	"1133.7"	"1548.9"	"1921.8"	"2585.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35232"	"Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1"	"50"	"12"	"32"	"12"	"272"	"29.8"	"5.76"	"7031.18"	"45.61"	"12"	"10"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01145"	"5245"	"ENSG00000167085"	"PHB1"	"B4DY47; hsa:5245; P35232; Q4VBQ0"	""	"Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; RAF activation; Processing of SMDT1"	"5"	"0"	"534.9"	"1743.6"	"1684.2"	"459.7"	"1423.1"	"641.4"	"1048.5"	"815.0"	"1141.1"	"1814.6"	"3308.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P12694"	"2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=BCKDHA PE=1 SV=2"	"28"	"12"	"28"	"12"	"445"	"50.4"	"8.27"	"5355.13"	"45.11"	"11"	"11"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00676"	"593"	"ENSG00000248098"	"BCKDHA"	"B4DP47; E7EW46; hsa:593; P12694; Q16034; Q16472"	"Lipid metabolism pathway"	"Glyoxylate metabolism and glycine degradation; Branched-chain amino acid catabolism"	"3"	"0"	"917.3"	"1813.2"	"1896.2"	"812.9"	"1565.9"	"822.7"	"1484.8"	"1303.2"	"1656.9"	"2092.0"	"2592.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P29692"	"Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5"	"47"	"13"	"29"	"11"	"281"	"31.1"	"5.01"	"5956.32"	"44.82"	"12"	"9"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00736, Pf10587"	"1936"	"ENSG00000104529; ENSG00000273594"	"EEF1D"	"B4DDU4; D3DWK3; E9PBQ9; hsa:1936; P29692; Q4VBZ6; Q969J1; Q96I38"	"Translation factors"	"Eukaryotic Translation Elongation"	"2"	"2"	"493.5"	"1091.9"	"1325.4"	"396.3"	"1172.1"	"522.6"	"1749.1"	"1318.0"	"1913.8"	"2657.2"	"4315.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46779"	"60S ribosomal protein L28 OS=Homo sapiens OX=9606 GN=RPL28 PE=1 SV=3"	"36"	"8"	"29"	"8"	"137"	"15.7"	"12.02"	"4049.31"	"44.79"	"8"	"8"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01778"	"6158"	"ENSG00000108107"	"RPL28"	"B2R4A6; B4DEP9; C9JB50; E9PB24; G5E9L2; hsa:6158; P46779; Q6IAY0; Q96FX1; Q9BWQ0"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis"	"14"	"0"	"976.9"	"2228.7"	"2056.0"	"834.4"	"2023.7"	"966.4"	"3458.0"	"2938.5"	"3275.5"	"4284.2"	"5601.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62249"	"40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2"	"55"	"12"	"36"	"12"	"146"	"16.4"	"10.21"	"6098.80"	"44.72"	"12"	"12"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00380"	"6217"	"ENSG00000105193"	"RPS16"	"B2RDD5; hsa:6217; P17008; P62249"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; SARS-CoV-2 modulates host translation machinery"	"19"	"0"	"938.7"	"2053.1"	"1865.8"	"908.1"	"1736.7"	"991.0"	"2505.9"	"2171.8"	"2521.9"	"3334.1"	"4758.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63241"	"Eukaryotic translation initiation factor 5A-1 OS=Homo sapiens OX=9606 GN=EIF5A PE=1 SV=2"	"42"	"8"	"28"	"8"	"154"	"16.8"	"5.24"	"5348.21"	"44.54"	"6"	"7"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf01287"	"1984"	"ENSG00000132507; ENSG00000288145"	"EIF5A"	"A8K9A0; D3DTP2; hsa:1984; P10159; P63241; Q16182; Q7L7L3; Q7Z4L1; Q9D0G2"	"Translation factors; eIF5A regulation in response to inhibition of the nuclear export system"	"Hypusine synthesis from eIF5A-lysine"	"3"	"0"	"654.6"	"1345.8"	"1446.3"	"445.0"	"1365.3"	"677.6"	"1051.9"	"1003.7"	"2835.9"	"5230.0"	"10965.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P2E9"	"Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5"	"16"	"18"	"31"	"17"	"1410"	"152.4"	"8.60"	"7120.83"	"44.50"	"15"	"11"	"protein metabolism;other metabolic processes;transport"	"other membranes;ER/Golgi;translational apparatus"	"other molecular function"	"Pf05104"	"6238"	"ENSG00000125844"	"RRBP1"	"A0A0A0MRV0; A2A2S6; A6NCN6; hsa:6238; O75300; O75301; Q5W165; Q96SB2; Q9BWP1; Q9H476; Q9P2E9"	"Ectoderm differentiation"	"Signaling by ALK fusions and activated point mutants"	"2"	"1"	"1510.2"	"2262.7"	"2397.3"	"1359.8"	"2447.7"	"1561.2"	"3389.6"	"2430.3"	"3578.6"	"4354.9"	"6110.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96C36"	"Pyrroline-5-carboxylate reductase 2 OS=Homo sapiens OX=9606 GN=PYCR2 PE=1 SV=1"	"30"	"11"	"25"	"10"	"320"	"33.6"	"7.77"	"4993.33"	"44.41"	"11"	"10"	"other metabolic processes;stress response"	"mitochondrion"	"other molecular function"	"Pf03807, Pf14748"	"29920"	"ENSG00000143811"	"PYCR2"	"A8K798; hsa:29920; Q7Z515; Q96C36; Q9Y5J4"	"Metabolic reprogramming in colon cancer"	"Glutamate and glutamine metabolism"	"2"	"1"	"1005.6"	"1472.7"	"1707.7"	"870.7"	"1584.0"	"1081.5"	"1950.7"	"1348.2"	"2040.6"	"2569.0"	"3856.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11387"	"DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2"	"17"	"14"	"37"	"14"	"765"	"90.7"	"9.31"	"4843.94"	"44.27"	"13"	"12"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf01028, Pf02919, Pf14370"	"7150"	"ENSG00000198900"	"TOP1"	"A8KA78; E1P5W3; hsa:7150; O43256; P11387; Q12855; Q12856; Q15610; Q5TFY3; Q9UJN0"	"Ebola virus infection in host"	"SUMOylation of DNA replication proteins"	"2"	"0"	"480.1"	"884.0"	"982.2"	"439.3"	"950.5"	"545.7"	"1269.0"	"1177.8"	"2824.7"	"3706.6"	"4011.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BUF5"	"Tubulin beta-6 chain OS=Homo sapiens OX=9606 GN=TUBB6 PE=1 SV=1"	"16"	"6"	"30"	"1"	"446"	"49.8"	"4.88"	"5271.07"	"44.24"	"5"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00091, Pf03953"	"84617"	"ENSG00000176014"	"TUBB6"	"B3KM76; hsa:84617; Q9BUF5; Q9HA42"	"Alzheimer's disease and miRNA effects; Pathogenic Escherichia coli infection; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"Prefoldin mediated transfer of substrate  to CCT/TriC; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; HCMV Early Events; Intraflagellar transport; Post-chaperonin tubulin folding pathway; Recycling pathway of L1; COPI-dependent Golgi-to-ER retrograde traffic; The role of GTSE1 in G2/M progression after G2 checkpoint; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane; Gap junction assembly; MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Recruitment of NuMA to mitotic centrosomes; Formation of tubulin folding intermediates by CCT/TriC; RHO GTPases activate IQGAPs; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Carboxyterminal post-translational modifications of tubulin; Assembly and cell surface presentation of NMDA receptors; Activation of AMPK downstream of NMDARs; Aggrephagy; Sealing of the nuclear envelope (NE) by ESCRT-III; Kinesins; Hedgehog 'off' state"	"34"	"0"	"29.7"	"102.2"	"98.5"	"28.8"	"81.7"	"35.2"	"52.9"	"46.7"	"68.8"	"89.2"	"149.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23921"	"Ribonucleoside-diphosphate reductase large subunit OS=Homo sapiens OX=9606 GN=RRM1 PE=1 SV=1"	"16"	"12"	"23"	"12"	"792"	"90.0"	"7.15"	"3993.66"	"43.80"	"11"	"12"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf00317, Pf02867, Pf03477"	"6240"	"ENSG00000167325"	"RRM1"	"hsa:6240; P23921; Q9UNN2"	"Fluoropyrimidine activity; Retinoblastoma gene in cancer; Pyrimidine metabolism"	"Interconversion of nucleotide di- and triphosphates"	"4"	"0"	"592.0"	"1079.5"	"1122.1"	"579.7"	"1215.0"	"727.0"	"1339.8"	"1009.5"	"1648.1"	"2377.9"	"4156.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96AG4"	"Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1"	"32"	"10"	"20"	"10"	"307"	"34.9"	"9.57"	"2920.62"	"43.80"	"7"	"9"	""	"other membranes;mitochondrion;ER/Golgi;nucleus;other cell component"	""	"Pf13855"	"55379"	"ENSG00000108829"	"LRRC59"	"B2RE83; D3DTX8; hsa:55379; Q96AG4; Q9P189"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"568.6"	"1138.1"	"1175.4"	"532.5"	"1036.9"	"655.9"	"1661.7"	"1460.9"	"2154.9"	"3686.0"	"6565.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60256"	"Phosphoribosyl pyrophosphate synthase-associated protein 2 OS=Homo sapiens OX=9606 GN=PRPSAP2 PE=1 SV=1"	"36"	"12"	"29"	"10"	"369"	"40.9"	"7.44"	"5414.97"	"43.72"	"12"	"11"	"other metabolic processes;developmental processes"	"other cell component"	"enzyme regulator activity;other molecular function"	"Pf13793, Pf14572"	"5636"	"ENSG00000141127"	"PRPSAP2"	"B4E1M8; B4E329; B7ZKZ1; E7EMY2; hsa:5636; O60256; Q6IAS2"	""	""	"0"	"1"	"497.5"	"998.4"	"996.1"	"442.9"	"873.8"	"522.6"	"710.3"	"760.1"	"1318.1"	"2731.8"	"4747.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q00341"	"Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2"	"12"	"14"	"28"	"14"	"1268"	"141.4"	"6.87"	"4629.63"	"43.71"	"12"	"14"	"other metabolic processes;transport"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013"	"3069"	"ENSG00000115677"	"HDLBP"	"B4DTQ2; E7EM71; hsa:3069; Q00341; Q53QU2; Q9UCY3"	"2q37 copy number variation syndrome"	"HDL clearance"	"2"	"0"	"765.1"	"1537.5"	"1641.3"	"694.0"	"1476.4"	"887.3"	"1746.7"	"1174.0"	"1887.6"	"2388.0"	"3637.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07814"	"Bifunctional glutamate/proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5"	"10"	"14"	"27"	"14"	"1512"	"170.5"	"7.33"	"4530.68"	"43.56"	"12"	"13"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00043, Pf00458, Pf00587, Pf00749, Pf03129, Pf03950, Pf09180"	"2058"	"ENSG00000136628"	"EPRS1"	"A0AVA9; B9EGH3; hsa:2058; P07814; Q05BP6; Q05DF8; Q5DSM1; Q5H9S5; Q6PD57; Q86X73"	"Parkinson's disease pathway; VEGFA-VEGFR2 signaling; Amino acid metabolism"	"tRNA modification in the nucleus and cytosol; Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"6"	"0"	"462.4"	"1775.7"	"1724.0"	"349.2"	"1304.1"	"542.5"	"1079.5"	"849.1"	"1220.8"	"1686.3"	"3071.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62280"	"40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3"	"46"	"10"	"29"	"10"	"158"	"18.4"	"10.30"	"5014.69"	"43.52"	"10"	"8"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00366, Pf16205"	"6205"	"ENSG00000142534"	"RPS11"	"B2R4F5; hsa:6205; P04643; P62280; Q498Y6; Q6IRY0"	"VEGFA-VEGFR2 signaling; IL-18 signaling pathway; Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"21"	"0"	"1078.1"	"2097.2"	"2115.6"	"979.0"	"2117.4"	"1104.1"	"2619.7"	"2048.5"	"2833.4"	"3545.4"	"5216.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q04917"	"14-3-3 protein eta OS=Homo sapiens OX=9606 GN=YWHAH PE=1 SV=4"	"27"	"7"	"25"	"3"	"246"	"28.2"	"4.84"	"3699.15"	"42.98"	"6"	"6"	"other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00244"	"7533"	"ENSG00000128245"	"YWHAH"	"hsa:7533; Q04917"	"Cell cycle; Myometrial relaxation and contraction pathways; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; TP53 Regulates Metabolic Genes; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Activation of BAD and translocation to mitochondria"	"11"	"0"	"206.9"	"484.3"	"403.8"	"157.5"	"361.5"	"202.9"	"382.0"	"506.7"	"645.8"	"604.2"	"1032.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NBS9"	"Thioredoxin domain-containing protein 5 OS=Homo sapiens OX=9606 GN=TXNDC5 PE=1 SV=2"	"30"	"12"	"26"	"12"	"432"	"47.6"	"5.97"	"4117.44"	"42.97"	"10"	"11"	"other biological processes"	"non-structural extracellular;ER/Golgi;other cytoplasmic organelle"	"other molecular function"	"Pf00085"	"81567"	"ENSG00000239264"	"TXNDC5"	"B2RDM2; hsa:81567; Q5TCQ0; Q8NBS9; Q8ND33; Q8TCT2; Q9BVH9"	"VEGFA-VEGFR2 signaling"	"Golgi Associated Vesicle Biogenesis; Neutrophil degranulation; Lysosome Vesicle Biogenesis"	"4"	"0"	"1315.1"	"2329.8"	"2611.3"	"1417.2"	"2364.7"	"1793.4"	"2021.7"	"1374.9"	"1719.9"	"1724.4"	"2171.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22061"	"Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens OX=9606 GN=PCMT1 PE=1 SV=4"	"28"	"5"	"32"	"5"	"227"	"24.6"	"7.21"	"6703.78"	"42.63"	"5"	"4"	"protein metabolism;other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf01135"	"5110"	"ENSG00000120265"	"PCMT1"	"A8K109; hsa:5110; J3KP72; P22061; Q14661; Q16556; Q5VYC1; Q5VYC2; Q93061; Q96II9; Q99625; Q9BQV7; Q9BQV8; Q9NP03"	"Primary ovarian insufficiency"	"Protein repair"	"2"	"0"	"636.5"	"1174.0"	"1219.4"	"599.4"	"1078.4"	"724.2"	"1064.1"	"821.3"	"1124.1"	"1342.6"	"1781.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q05682"	"Caldesmon OS=Homo sapiens OX=9606 GN=CALD1 PE=1 SV=3"	"16"	"12"	"22"	"12"	"793"	"93.2"	"5.66"	"4142.05"	"42.35"	"9"	"10"	"cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton"	"cytoskeletal activity;other molecular function"	"Pf02029"	"800"	"ENSG00000122786"	"CALD1"	"A8K0X1; hsa:800; Q05682; Q13978; Q13979; Q14741; Q14742; Q9UD91"	"Myometrial relaxation and contraction pathways"	"Smooth Muscle Contraction"	"2"	"0"	"1085.2"	"1426.1"	"1518.0"	"930.8"	"1658.9"	"986.6"	"2847.6"	"1948.3"	"2724.8"	"3109.4"	"3703.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2A7"	"Nck-associated protein 1 OS=Homo sapiens OX=9606 GN=NCKAP1 PE=1 SV=1"	"11"	"11"	"24"	"11"	"1128"	"128.7"	"6.62"	"3656.53"	"41.78"	"10"	"11"	"cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	""	"Pf09735"	"10787"	"ENSG00000061676"	"NCKAP1"	"hsa:10787; O60329; Q53QN5; Q53S94; Q53Y35; Q9Y2A7"	"Exercise-induced circadian regulation; Regulation of actin cytoskeleton"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; VEGFA-VEGFR2 Pathway"	"9"	"0"	"358.1"	"688.1"	"752.6"	"336.0"	"669.8"	"383.4"	"1259.9"	"1183.4"	"1752.1"	"2712.1"	"4213.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01105"	"Protein SET OS=Homo sapiens OX=9606 GN=SET PE=1 SV=3"	"27"	"7"	"22"	"7"	"290"	"33.5"	"4.32"	"3911.50"	"41.66"	"6"	"6"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00956"	"6418"	"ENSG00000119335"	"SET"	"A5A5H4; A6NGV1; B4DUE2; hsa:6418; Q01105; Q15541; Q5VXV1; Q5VXV2; Q6FHZ5"	"Histone modifications; VEGFA-VEGFR2 signaling"	"HuR (ELAVL1) binds and stabilizes mRNA; Condensation of Prophase Chromosomes"	"4"	"0"	"573.3"	"1558.4"	"1493.9"	"510.6"	"1324.2"	"651.2"	"1520.1"	"1221.3"	"1614.3"	"1771.9"	"2870.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55209"	"Nucleosome assembly protein 1-like 1 OS=Homo sapiens OX=9606 GN=NAP1L1 PE=1 SV=1"	"26"	"7"	"20"	"6"	"391"	"45.3"	"4.46"	"3128.71"	"41.58"	"5"	"7"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00956"	"4673"	"ENSG00000187109"	"NAP1L1"	"B3KNT8; B3KV44; hsa:4673; P55209"	"VEGFA-VEGFR2 signaling; Overlap between signal transduction pathways contributing to LMNA laminopathies"	""	"2"	"1"	"267.8"	"670.1"	"635.6"	"247.5"	"609.1"	"346.5"	"409.2"	"334.2"	"468.5"	"526.7"	"869.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y606"	"tRNA pseudouridine synthase A OS=Homo sapiens OX=9606 GN=PUS1 PE=1 SV=3"	"28"	"11"	"21"	"11"	"427"	"47.4"	"8.41"	"3036.87"	"41.38"	"8"	"11"	"RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01416"	"80324"	"ENSG00000177192"	"PUS1"	"A8K877; B3KQC1; hsa:80324; Q8WYT2; Q9BU44; Q9Y606"	""	""	"0"	"0"	"291.2"	"507.8"	"555.8"	"261.4"	"562.9"	"323.5"	"605.2"	"571.1"	"1290.2"	"1976.3"	"3480.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P16152"	"Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3"	"38"	"9"	"21"	"9"	"277"	"30.4"	"8.32"	"3540.68"	"41.37"	"7"	"9"	"other metabolic processes;other biological processes"	"cytosol"	"other molecular function"	"Pf00106"	"873"	"ENSG00000159228"	"CBR1"	"B2RBZ7; B4DFK7; hsa:873; P16152; Q3LHW8"	"Nuclear receptors meta-pathway; NRF2 pathway; Prostaglandin synthesis and regulation"	"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)"	"4"	"0"	"605.5"	"1460.6"	"1508.1"	"563.4"	"1463.2"	"673.2"	"1038.7"	"753.0"	"1031.4"	"1318.5"	"2075.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TAF3"	"WD repeat-containing protein 48 OS=Homo sapiens OX=9606 GN=WDR48 PE=1 SV=1"	"25"	"11"	"15"	"11"	"677"	"76.2"	"7.03"	"1510.00"	"41.27"	"4"	"11"	"DNA metabolism;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00400, Pf11816"	"57599"	"ENSG00000114742"	"WDR48"	"B4DM86; B4DQI2; B4DY84; hsa:57599; Q63HJ2; Q658Y1; Q8N3Z1; Q8TAF3; Q9NSK8; Q9P279"	"DNA repair pathways, full network"	"Ub-specific processing proteases; Fanconi Anemia Pathway; Signaling by cytosolic PDGFRA and PDGFRB fusion proteins; Recognition of DNA damage by PCNA-containing replication complex"	"5"	"0"	"215.4"	"496.8"	"488.1"	"212.9"	"494.8"	"270.6"	"557.3"	"507.8"	"833.5"	"1647.2"	"3146.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11908"	"Ribose-phosphate pyrophosphokinase 2 OS=Homo sapiens OX=9606 GN=PRPS2 PE=1 SV=2"	"24"	"9"	"26"	"2"	"318"	"34.7"	"6.61"	"4643.52"	"41.23"	"9"	"9"	"other metabolic processes;other biological processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf13793, Pf14572"	"5634"	"ENSG00000101911"	"PRPS2"	"hsa:5634; P11908; Q0VDH9; Q0VDI0; Q15245; Q2TAK7"	""	"5-Phosphoribose 1-diphosphate biosynthesis"	"1"	"0"	"82.1"	"120.6"	"139.4"	"81.3"	"151.1"	"114.5"	"152.7"	"112.8"	"198.6"	"269.5"	"378.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BY44"	"Eukaryotic translation initiation factor 2A OS=Homo sapiens OX=9606 GN=EIF2A PE=1 SV=3"	"24"	"13"	"26"	"13"	"585"	"64.9"	"8.87"	"4305.77"	"41.17"	"12"	"11"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;translational apparatus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf08662"	"83939"	"ENSG00000144895"	"EIF2A"	"A8MPS6; B4DF96; B4DQ14; D3DNI9; hsa:83939; Q5QTR2; Q7Z4E9; Q8NFM1; Q96EW9; Q96K81; Q9BY44"	"Photodynamic therapy-induced unfolded protein response; VEGFA-VEGFR2 signaling; 7q11.23 copy number variation syndrome"	""	"3"	"0"	"811.5"	"1263.4"	"1374.4"	"699.6"	"1250.7"	"845.1"	"1594.8"	"1195.5"	"1786.3"	"2763.7"	"4906.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15084"	"Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1"	"28"	"11"	"24"	"11"	"440"	"48.1"	"5.08"	"4163.37"	"41.06"	"8"	"10"	"stress response;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00085"	"10130"	"ENSG00000143870"	"PDIA6"	"B3KY95; B5MCQ5; B7Z254; B7Z4M8; F8WA83; hsa:10130; Q15084; Q53RC7; Q6ZSH5; Q99778"	"Photodynamic therapy-induced unfolded protein response; VEGFA-VEGFR2 signaling"	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; XBP1(S) activates chaperone genes"	"5"	"0"	"1026.6"	"2426.3"	"2554.2"	"1132.8"	"2352.7"	"1457.6"	"1990.4"	"1424.2"	"1799.4"	"2045.4"	"2650.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99613"	"Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1"	"11"	"10"	"24"	"10"	"913"	"105.3"	"5.68"	"5108.58"	"40.78"	"10"	"8"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf01399, Pf05470"	"8663"	"ENSG00000184110"	"EIF3C"	"A8K7Z0; B2RXG3; B4E1D5; H3BRV0; hsa:8663; O00215; Q99613; Q9BW98"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex"	"8"	"0"	"523.3"	"861.0"	"1044.8"	"472.8"	"936.7"	"590.3"	"1013.2"	"741.9"	"1149.6"	"1400.1"	"1893.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13797"	"Plastin-3 OS=Homo sapiens OX=9606 GN=PLS3 PE=1 SV=4"	"24"	"11"	"24"	"11"	"630"	"70.8"	"5.60"	"4478.50"	"40.71"	"9"	"11"	"cell organization and biogenesis;developmental processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf13499"	"5358"	"ENSG00000102024"	"PLS3"	"A8K579; B1AQ09; B4DGB4; B7Z6M1; hsa:5358; P13797; Q86YI6"	""	""	"0"	"0"	"330.3"	"1272.3"	"1077.0"	"270.7"	"969.3"	"428.3"	"524.4"	"427.2"	"590.8"	"736.4"	"1284.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55884"	"Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3"	"18"	"12"	"22"	"12"	"814"	"92.4"	"5.00"	"3182.63"	"40.63"	"10"	"11"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08662"	"8662"	"ENSG00000106263"	"EIF3B"	"A4D208; hsa:8662; P55884; Q2NL77; Q9UMF9"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"8"	"0"	"491.3"	"1107.6"	"1200.8"	"451.3"	"1044.5"	"581.4"	"873.6"	"684.8"	"975.8"	"1345.0"	"1962.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P48739"	"Phosphatidylinositol transfer protein beta isoform OS=Homo sapiens OX=9606 GN=PITPNB PE=1 SV=2"	"42"	"9"	"20"	"8"	"271"	"31.5"	"6.87"	"3401.57"	"40.61"	"7"	"9"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;ER/Golgi;other cell component"	"transporter activity;other molecular function"	"Pf02121"	"23760"	"ENSG00000180957"	"PITPNB"	"B3KYB8; B7Z7Q0; hsa:23760; P48739; Q8N5W1"	""	"PI and PC transport between ER and Golgi membranes"	"1"	"1"	"653.0"	"1308.5"	"1216.9"	"528.5"	"1309.6"	"653.9"	"1136.4"	"936.0"	"1280.7"	"1712.6"	"2531.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5X1"	"Sorting nexin-9 OS=Homo sapiens OX=9606 GN=SNX9 PE=1 SV=1"	"25"	"14"	"22"	"14"	"595"	"66.6"	"5.58"	"3294.85"	"40.58"	"8"	"13"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf00018, Pf00787, Pf10456"	"51429"	"ENSG00000130340"	"SNX9"	"hsa:51429; Q9BSI7; Q9BVM1; Q9UJH6; Q9UP20; Q9Y5X1"	""	"Clathrin-mediated endocytosis; Golgi Associated Vesicle Biogenesis"	"2"	"0"	"202.1"	"407.0"	"569.6"	"213.8"	"474.4"	"278.1"	"946.5"	"1474.9"	"2768.4"	"4375.4"	"5860.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7L576"	"Cytoplasmic FMR1-interacting protein 1 OS=Homo sapiens OX=9606 GN=CYFIP1 PE=1 SV=1"	"10"	"12"	"27"	"6"	"1253"	"145.1"	"6.90"	"4467.94"	"40.58"	"11"	"12"	"cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf05994, Pf07159"	"23191"	"ENSG00000273749; ENSG00000288461"	"CYFIP1"	"A8K6D9; hsa:23191; Q14467; Q5IED0; Q6ZSX1; Q7L576; Q9BSD9; Q9BVC7"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; Prader-Willi and Angelman syndrome; Fragile X syndrome; Disruption of postsynaptic signaling by CNV; 15q11.2 copy number variation syndrome; G13 signaling pathway"	"Neutrophil degranulation; VEGFA-VEGFR2 Pathway; RAC3 GTPase cycle; RAC1 GTPase cycle; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHOG GTPase cycle; RHO GTPases Activate WASPs and WAVEs; RAC2 GTPase cycle"	"15"	"4"	"234.2"	"289.7"	"360.9"	"172.2"	"349.7"	"239.5"	"756.0"	"552.7"	"957.5"	"1414.0"	"2250.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86VN1"	"Vacuolar protein-sorting-associated protein 36 OS=Homo sapiens OX=9606 GN=VPS36 PE=1 SV=1"	"25"	"11"	"23"	"11"	"386"	"43.8"	"7.20"	"4238.65"	"40.26"	"10"	"10"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport"	"other membranes;cytosol;nucleus;other cytoplasmic organelle"	"other molecular function"	"Pf04157, Pf11605"	"51028"	"ENSG00000136100"	"VPS36"	"A8K125; hsa:51028; Q3ZCV7; Q5H9S1; Q5VXB6; Q86VN1; Q9H8Z5; Q9Y3E3"	"Network map of SARS-CoV-2 signaling pathway"	"Endosomal Sorting Complex Required For Transport (ESCRT); HCMV Late Events"	"3"	"0"	"291.8"	"619.5"	"653.1"	"281.6"	"685.4"	"358.1"	"1071.7"	"1536.7"	"2434.5"	"3949.1"	"7470.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P2T1"	"GMP reductase 2 OS=Homo sapiens OX=9606 GN=GMPR2 PE=1 SV=1"	"24"	"7"	"16"	"6"	"348"	"37.9"	"7.23"	"1214.05"	"39.93"	"3"	"6"	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00478"	"51292"	"ENSG00000100938; ENSG00000284752"	"GMPR2"	"D3DS66; hsa:51292; Q567T0; Q6IAJ8; Q86T14; Q9P2T1"	""	"Purine salvage"	"1"	"1"	"232.4"	"450.5"	"496.3"	"210.7"	"551.8"	"310.1"	"595.0"	"476.5"	"1336.0"	"5093.6"	"13651.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P26641"	"Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3"	"28"	"12"	"27"	"12"	"437"	"50.1"	"6.67"	"4672.04"	"39.71"	"11"	"10"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity"	"Pf00043, Pf00647, Pf02798"	"1937"	"ENSG00000254772"	"EEF1G"	"B4DTG2; hsa:1937; P26641; Q6PJ62; Q6PK31; Q96CU2; Q9P196"	"Translation factors"	"Signaling by ALK fusions and activated point mutants; Eukaryotic Translation Elongation"	"3"	"0"	"876.0"	"2087.9"	"2311.8"	"795.2"	"2059.8"	"1041.0"	"2814.2"	"1974.5"	"2845.1"	"4174.5"	"6113.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60869"	"Endothelial differentiation-related factor 1 OS=Homo sapiens OX=9606 GN=EDF1 PE=1 SV=1"	"56"	"11"	"28"	"11"	"148"	"16.4"	"9.95"	"5735.47"	"39.69"	"10"	"8"	"RNA metabolism OR transcription;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01381, Pf08523"	"8721"	"ENSG00000107223"	"EDF1"	"hsa:8721; O60869; Q5T5T2; Q9UIM1"	""	""	"0"	"0"	"868.7"	"1271.1"	"1326.5"	"738.2"	"1320.6"	"826.2"	"4654.2"	"3505.9"	"4547.0"	"5116.4"	"6909.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P21333"	"Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4"	"5"	"11"	"22"	"10"	"2647"	"280.6"	"6.06"	"3860.27"	"39.48"	"8"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00307, Pf00630"	"2316"	"ENSG00000196924"	"FLNA"	"E9KL45; hsa:2316; P21333; Q5HY53; Q5HY55; Q8NF52"	"Androgen receptor signaling pathway; Prolactin signaling pathway; Focal adhesion; Hypothesized pathways in pathogenesis of cardiovascular disease; MAPK signaling pathway; IL-4 signaling pathway; Ebola virus infection in host; Joubert syndrome"	"OAS antiviral response; Platelet degranulation ; RHO GTPases activate PAKs; GP1b-IX-V activation signalling; Cell-extracellular matrix interactions"	"13"	"2"	"420.1"	"948.0"	"1120.6"	"343.1"	"1018.5"	"464.9"	"1501.6"	"1166.3"	"1656.8"	"2143.5"	"3339.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06744"	"Glucose-6-phosphate isomerase OS=Homo sapiens OX=9606 GN=GPI PE=1 SV=4"	"20"	"9"	"25"	"9"	"558"	"63.1"	"8.32"	"4618.43"	"39.27"	"9"	"8"	"other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00342"	"2821"	"ENSG00000105220"	"GPI"	"B4DG39; hsa:2821; P06744; Q9BRD3; Q9BSK5; Q9UHE6"	"Cori cycle; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Aerobic glycolysis; N-glycan biosynthesis; Disorders of fructose metabolism; Glycolysis and gluconeogenesis; UDP-derived sugars synthesis in fibroblasts"	"Neutrophil degranulation; TP53 Regulates Metabolic Genes; Glycolysis; Gluconeogenesis"	"12"	"0"	"409.9"	"1746.7"	"1820.2"	"383.8"	"1597.4"	"616.8"	"1026.0"	"2702.6"	"1589.7"	"1097.8"	"2281.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62913"	"60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2"	"40"	"10"	"26"	"10"	"178"	"20.2"	"9.60"	"4167.29"	"39.21"	"8"	"9"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00281, Pf00673"	"6135"	"ENSG00000142676"	"RPL11"	"hsa:6135; P25121; P39026; P62913; Q8TDH2; Q9Y674"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"1270.9"	"2346.8"	"2426.6"	"1014.0"	"2532.2"	"1191.7"	"4483.0"	"3277.6"	"4187.3"	"4923.2"	"6726.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99832"	"T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2"	"27"	"12"	"23"	"12"	"543"	"59.3"	"7.65"	"3541.32"	"39.06"	"10"	"11"	"transport;other biological processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00118"	"10574"	"ENSG00000135624"	"CCT7"	"A8K7E6; A8MWI8; B7WNW9; B7Z4T9; B7Z4Z7; hsa:10574; O14871; Q6FI26; Q99832"	"VEGFA-VEGFR2 signaling; 16p11.2 proximal deletion syndrome"	"Formation of tubulin folding intermediates by CCT/TriC; RHOBTB1 GTPase cycle; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; RHOBTB2 GTPase cycle; Folding of actin by CCT/TriC"	"9"	"0"	"777.1"	"2058.6"	"2143.5"	"636.6"	"1586.5"	"798.9"	"815.6"	"656.3"	"853.8"	"1237.7"	"2126.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49327"	"Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3"	"6"	"13"	"24"	"13"	"2511"	"273.3"	"6.44"	"3411.87"	"39.04"	"11"	"13"	"other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00107, Pf00109, Pf00550, Pf00698, Pf00975, Pf02801, Pf08242, Pf08659, Pf14765, Pf16197"	"2194"	"ENSG00000169710"	"FASN"	"hsa:2194; P49327; Q13479; Q16702; Q4LE83; Q6P4U5; Q6SS02; Q969R1; Q96C68; Q96IT0"	"AMP-activated protein kinase signaling; Sterol regulatory element-binding proteins (SREBP) signaling; SREBF and miR33 in cholesterol and lipid homeostasis; Liver X receptor pathway; Nuclear receptors meta-pathway; Fatty acid biosynthesis; Angiopoietin-like protein 8 regulatory pathway; Lipid metabolism pathway; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Omega-9 fatty acid synthesis; FOXA2 pathway"	"ChREBP activates metabolic gene expression; Activation of gene expression by SREBF (SREBP); Fatty acyl-CoA biosynthesis; NR1H2 & NR1H3 regulate gene expression linked to lipogenesis; Vitamin B5 (pantothenate) metabolism"	"18"	"0"	"493.7"	"1572.1"	"1316.8"	"415.9"	"1193.8"	"527.3"	"660.6"	"517.8"	"778.2"	"988.5"	"1661.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50914"	"60S ribosomal protein L14 OS=Homo sapiens OX=9606 GN=RPL14 PE=1 SV=4"	"40"	"11"	"29"	"11"	"215"	"23.4"	"10.93"	"5059.79"	"38.83"	"9"	"8"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01929"	"9045"	"ENSG00000188846"	"RPL14"	"hsa:9045; P50914; Q45RF0; Q53G20; Q8TBD5; Q8WUT0; Q92579; Q96GR0; Q9BSB8; Q9BW65; Q9BYF6"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"1176.7"	"2589.8"	"2477.6"	"1057.1"	"2433.3"	"1228.4"	"4899.9"	"3902.3"	"4651.2"	"5867.9"	"7629.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60842"	"Eukaryotic initiation factor 4A-I OS=Homo sapiens OX=9606 GN=EIF4A1 PE=1 SV=1"	"27"	"8"	"21"	"7"	"406"	"46.1"	"5.48"	"4992.83"	"38.74"	"7"	"7"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"1973"	"ENSG00000161960"	"EIF4A1"	"B2R6L8; D3DTP9; hsa:1973; J3QLC4; P04765; P60842; Q5U018; Q61516"	"Translation factors; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Interferon type I signaling pathways"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; ISG15 antiviral mechanism; Deadenylation of mRNA"	"11"	"1"	"744.5"	"1869.2"	"1867.4"	"706.2"	"1661.1"	"977.2"	"1434.1"	"1181.5"	"1346.0"	"1637.9"	"2286.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46776"	"60S ribosomal protein L27a OS=Homo sapiens OX=9606 GN=RPL27A PE=1 SV=2"	"30"	"7"	"21"	"7"	"148"	"16.6"	"11.00"	"3501.25"	"38.52"	"6"	"7"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;other cell component"	"other molecular function"	"Pf00828"	"6157"	"ENSG00000166441"	"RPL27A"	"B2R4B3; hsa:6157; P46776"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"523.3"	"1048.4"	"1196.0"	"480.5"	"1197.0"	"574.4"	"1673.2"	"1190.5"	"1676.2"	"2024.1"	"3302.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P41091"	"Eukaryotic translation initiation factor 2 subunit 3 OS=Homo sapiens OX=9606 GN=EIF2S3 PE=1 SV=3"	"21"	"8"	"20"	"8"	"472"	"51.1"	"8.40"	"3317.44"	"38.35"	"5"	"8"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03144, Pf09173"	"1968"	"ENSG00000130741"	"EIF2S3"	"A0A024RBY4; A8K2Y2; B2R5N2; B5BTZ4; hsa:1968; P41091; Q53HK3"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; ABC-family proteins mediated transport; Response of EIF2AK1 (HRI) to heme deficiency; PERK regulates gene expression; Recycling of eIF2:GDP; Response of EIF2AK4 (GCN2) to amino acid deficiency"	"12"	"0"	"372.0"	"610.6"	"770.8"	"342.0"	"700.6"	"431.1"	"1047.6"	"868.7"	"1255.1"	"2123.1"	"4208.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95831"	"Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1"	"19"	"8"	"18"	"8"	"613"	"66.9"	"8.95"	"3229.40"	"38.27"	"6"	"8"	"cell organization and biogenesis;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00070, Pf14721"	"9131"	"ENSG00000156709"	"AIFM1"	"A4QPB4; B1ALN1; B2RB08; D3DTE9; E9PRR0; hsa:9131; O95831; Q1L6K4; Q1L6K6; Q2QKE4; Q5JUZ7; Q6I9X6; Q9Y3I3; Q9Y3I4"	"Apoptosis modulation and signaling; Nanomaterial induced apoptosis; Apoptosis modulation by HSP70"	""	"3"	"0"	"364.6"	"938.0"	"881.6"	"365.9"	"787.6"	"387.0"	"637.7"	"514.2"	"720.0"	"859.6"	"1234.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30050"	"60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1"	"65"	"10"	"24"	"10"	"165"	"17.8"	"9.42"	"4193.31"	"38.14"	"8"	"9"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00298, Pf03946"	"6136"	"ENSG00000197958"	"RPL12"	"hsa:6136; P30050; Q5VVV2; Q6PB27"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"1084.4"	"2570.4"	"2348.2"	"1013.8"	"2154.6"	"1090.3"	"2387.6"	"1696.7"	"2382.2"	"3027.7"	"4929.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P17980"	"26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3 PE=1 SV=3"	"32"	"11"	"27"	"11"	"439"	"49.2"	"5.24"	"5972.48"	"38.00"	"11"	"10"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf16450, Pf17862"	"5702"	"ENSG00000165916"	"PSMC3"	"B2R8V1; hsa:5702; P17980; Q3B757; Q3B865; Q53HU5; Q6GPG8; Q6IBS1; Q96HD3"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"Neutrophil degranulation; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Separation of Sister Chromatids; ABC-family proteins mediated transport; Defective CFTR causes cystic fibrosis; UCH proteinases; Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of expression of SLITs and ROBOs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; MAPK6/MAPK4 signaling; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"64"	"0"	"669.5"	"1569.5"	"1598.3"	"596.5"	"1427.1"	"757.9"	"973.6"	"808.2"	"1150.9"	"1507.0"	"2413.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13310"	"Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1"	"20"	"11"	"24"	"6"	"644"	"70.7"	"9.26"	"4054.27"	"37.46"	"11"	"11"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf00658"	"8761"	"ENSG00000090621"	"PABPC4"	"B1ANQ8; hsa:8761; Q13310; Q4VC03; Q6P0N3"	""	""	"0"	"0"	"512.8"	"1106.8"	"1143.2"	"475.3"	"1066.3"	"603.1"	"1011.0"	"713.3"	"1056.5"	"1199.3"	"1714.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q07020"	"60S ribosomal protein L18 OS=Homo sapiens OX=9606 GN=RPL18 PE=1 SV=2"	"38"	"9"	"21"	"9"	"188"	"21.6"	"11.72"	"3510.73"	"37.42"	"9"	"9"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf17135"	"6141"	"ENSG00000063177"	"RPL18"	"F8VWC5; hsa:6141; Q07020; Q8WTZ6"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis"	"14"	"0"	"564.1"	"1004.2"	"1025.3"	"506.2"	"1103.9"	"547.5"	"1594.1"	"1145.5"	"1449.9"	"1780.0"	"2491.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y520"	"Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4"	"5"	"13"	"24"	"12"	"2896"	"316.7"	"9.13"	"3408.12"	"37.13"	"11"	"13"	"cell organization and biogenesis;other biological processes"	"cytosol;other cell component"	""	"Pf07001"	"23215"	"ENSG00000117523"	"PRRC2C"	"hsa:23215; Q05DM8; Q49A39; Q6PD54; Q9H2N2; Q9HA05; Q9NSM8; Q9NXL3; Q9UF29; Q9UPQ6; Q9Y520"	"VEGFA-VEGFR2 signaling"	""	"1"	"1"	"848.3"	"1228.2"	"1295.9"	"663.8"	"1272.1"	"815.5"	"2547.9"	"1871.1"	"2563.5"	"2963.0"	"4198.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16181"	"Septin-7 OS=Homo sapiens OX=9606 GN=SEPTIN7 PE=1 SV=2"	"22"	"8"	"21"	"7"	"437"	"50.6"	"8.63"	"3595.32"	"37.12"	"8"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00735"	"989"	"ENSG00000122545"	"SEPTIN7"	"hsa:989; Q16181; Q52M76; Q6NX50"	""	"MAPK6/MAPK4 signaling"	"1"	"1"	"272.7"	"495.4"	"623.6"	"257.0"	"639.4"	"358.9"	"1281.4"	"869.0"	"1444.2"	"2081.8"	"4001.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3F4"	"Serine-threonine kinase receptor-associated protein OS=Homo sapiens OX=9606 GN=STRAP PE=1 SV=1"	"31"	"7"	"18"	"7"	"350"	"38.4"	"5.12"	"3224.54"	"37.11"	"5"	"7"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00400"	"11171"	"ENSG00000023734"	"STRAP"	"B2R5S5; B4DNJ6; hsa:11171; Q5TZT4; Q9NTK0; Q9UQC8; Q9Y3F4"	"Epithelial to mesenchymal transition in colorectal cancer"	"Downregulation of TGF-beta receptor signaling"	"2"	"0"	"1035.0"	"2091.6"	"2228.3"	"840.3"	"1942.7"	"1197.7"	"1356.9"	"871.1"	"1326.1"	"1334.1"	"2212.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P78371"	"T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4"	"30"	"13"	"28"	"13"	"535"	"57.5"	"6.46"	"5144.35"	"37.11"	"10"	"9"	"cell organization and biogenesis;transport;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00118"	"10576"	"ENSG00000166226"	"CCT2"	"A8K402; B5BTY7; B7Z243; B7Z7K4; B7ZAT2; hsa:10576; P78371; Q14D36; Q6IAT3"	"16p11.2 proximal deletion syndrome"	"Neutrophil degranulation; Formation of tubulin folding intermediates by CCT/TriC; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; RHOBTB2 GTPase cycle; Folding of actin by CCT/TriC; BBSome-mediated cargo-targeting to cilium; RHOBTB1 GTPase cycle"	"10"	"0"	"662.0"	"1937.5"	"1791.1"	"530.4"	"1352.8"	"706.0"	"1150.7"	"980.9"	"1349.9"	"1770.8"	"2841.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75821"	"Eukaryotic translation initiation factor 3 subunit G OS=Homo sapiens OX=9606 GN=EIF3G PE=1 SV=2"	"24"	"7"	"16"	"7"	"320"	"35.6"	"6.13"	"3341.21"	"37.08"	"6"	"7"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf12353"	"8666"	"ENSG00000130811"	"EIF3G"	"hsa:8666; O14801; O75821; Q969U5"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"8"	"0"	"467.3"	"874.2"	"1007.6"	"434.2"	"919.8"	"573.5"	"857.1"	"604.8"	"924.6"	"1200.0"	"1797.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P27348"	"14-3-3 protein theta OS=Homo sapiens OX=9606 GN=YWHAQ PE=1 SV=1"	"28"	"6"	"23"	"3"	"245"	"27.7"	"4.78"	"3773.45"	"37.01"	"6"	"6"	"transport;signal transduction;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00244"	"10971"	"ENSG00000134308"	"YWHAQ"	"D6W4Z5; hsa:10971; P27348; Q567U5; Q5TZU8; Q9UP48"	"Cell cycle; Pathogenic Escherichia coli infection; Primary focal segmental glomerulosclerosis (FSGS); IL-3 signaling pathway; Myometrial relaxation and contraction pathways; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-YAP signaling; Leukocyte-intrinsic Hippo pathway functions; Hepatitis B infection; Opioid receptor pathways; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"TP53 Regulates Metabolic Genes; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Regulation of localization of FOXO transcription factors; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Activation of BAD and translocation to mitochondria"	"20"	"0"	"204.7"	"591.1"	"576.9"	"204.0"	"520.3"	"290.6"	"319.6"	"222.7"	"351.4"	"422.4"	"753.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P0DP25"	"Calmodulin-3 OS=Homo sapiens OX=9606 GN=CALM3 PE=1 SV=1"	"52"	"9"	"21"	"9"	"149"	"16.8"	"4.22"	"3610.60"	"36.61"	"7"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;mitochondrion;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf13499"	"801; 805; 808"	"ENSG00000160014"	"CALM3"	"hsa:801; hsa:805; hsa:808; P02593; P0DP25; P62158; P70667; P99014; Q13942; Q53S29; Q61379; Q61380; Q96HK3"	"Physiological and pathological hypertrophy of the heart; MicroRNAs in cardiomyocyte hypertrophy; Alzheimer's disease and miRNA effects; T cell receptor and co-stimulatory signaling; Cardiac hypertrophic response; Myometrial relaxation and contraction pathways; G protein signaling pathways; Ras signaling; Melanoma; Endochondral ossification; Endochondral ossification with skeletal dysplasias; CAMKK2 pathway; Glycogen synthesis and degradation; Neuroinflammation and glutamatergic signaling; Alzheimer's disease; G13 signaling pathway; Calcium regulation in cardiac cells"	""	"17"	"0"	"657.1"	"1713.3"	"1643.3"	"485.7"	"1369.3"	"663.6"	"1087.3"	"1087.1"	"1868.1"	"2785.5"	"5380.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05141"	"ADP/ATP translocase 2 OS=Homo sapiens OX=9606 GN=SLC25A5 PE=1 SV=7"	"35"	"11"	"26"	"4"	"298"	"32.8"	"9.69"	"4366.50"	"36.52"	"9"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytoskeleton;mitochondrion"	"transporter activity;other molecular function"	"Pf00153"	"292"	"ENSG00000005022"	"SLC25A5"	"B2RCV1; hsa:292; O43350; P05141"	"Electron transport chain: OXPHOS system in mitochondria; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane; Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization"	"5"	"7"	"902.9"	"3145.9"	"2643.0"	"781.0"	"2221.1"	"925.0"	"1322.1"	"1033.5"	"1361.9"	"2140.0"	"3689.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q10567"	"AP-1 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP1B1 PE=1 SV=2"	"14"	"13"	"24"	"4"	"949"	"104.6"	"5.06"	"3447.01"	"36.35"	"10"	"12"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"61.8"	"174.9"	"164.8"	"63.3"	"165.3"	"83.6"	"138.7"	"204.9"	"465.7"	"781.3"	"1132.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A6NHR9"	"Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2"	"6"	"11"	"23"	"11"	"2005"	"226.2"	"7.30"	"4323.85"	"36.35"	"10"	"9"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06470, Pf13589"	"23347"	"ENSG00000101596"	"SMCHD1"	"A6NHR9; hsa:23347; O75141; Q6AHX6; Q6ZTQ8; Q9H6Q2; Q9UG39"	""	""	"0"	"0"	"572.3"	"930.4"	"1051.2"	"530.6"	"1036.1"	"636.6"	"1203.9"	"955.4"	"1488.5"	"1962.2"	"2588.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25685"	"DnaJ homolog subfamily B member 1 OS=Homo sapiens OX=9606 GN=DNAJB1 PE=1 SV=4"	"33"	"11"	"24"	"10"	"340"	"38.0"	"8.63"	"4142.28"	"35.86"	"10"	"10"	"RNA metabolism OR transcription;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00226, Pf01556"	"3337"	"ENSG00000132002"	"DNAJB1"	"B4DX52; hsa:3337; P25685"	"Nuclear receptors meta-pathway; NRF2 pathway"	"MAPK6/MAPK4 signaling; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Regulation of HSF1-mediated heat shock response; Attenuation phase"	"7"	"1"	"641.8"	"1367.4"	"1572.6"	"585.1"	"1477.6"	"863.8"	"1894.3"	"1259.0"	"1912.0"	"2657.5"	"4114.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51610"	"Host cell factor 1 OS=Homo sapiens OX=9606 GN=HCFC1 PE=1 SV=2"	"6"	"9"	"16"	"9"	"2035"	"208.6"	"7.46"	"2831.44"	"35.65"	"6"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf01344, Pf13415"	"3054"	"ENSG00000172534"	"HCFC1"	"hsa:3054; P51610; Q6P4G5"	"Mitochondrial gene expression; Pleural mesothelioma"	"UCH proteinases; Formation of WDR5-containing histone-modifying complexes; Transcriptional activation of mitochondrial biogenesis; HATs acetylate histones"	"6"	"0"	"727.3"	"1200.0"	"1137.7"	"584.1"	"1049.0"	"712.2"	"2190.3"	"1498.5"	"2040.7"	"2386.2"	"3197.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15371"	"Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1"	"22"	"9"	"18"	"9"	"548"	"63.9"	"6.05"	"2298.14"	"35.60"	"7"	"9"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf05091"	"8664"	"ENSG00000100353"	"EIF3D"	"A8MWD3; B2R7D4; B4DTF8; B4DVY1; hsa:8664; O15371; Q3MJD9; Q5M9Q6"	"Translation factors; VEGFA-VEGFR2 signaling; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"9"	"0"	"226.8"	"514.0"	"553.7"	"230.3"	"519.0"	"266.7"	"386.8"	"288.8"	"425.0"	"631.2"	"1035.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15459"	"Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1"	"15"	"9"	"18"	"9"	"793"	"88.8"	"5.22"	"3593.32"	"35.58"	"7"	"9"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00240, Pf01805, Pf12230"	"10291"	"ENSG00000099995"	"SF3A1"	"E9PAW1; hsa:10291; Q15459"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"417.2"	"686.6"	"756.7"	"379.4"	"693.1"	"485.7"	"1024.4"	"792.9"	"1037.8"	"1338.8"	"1569.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P258"	"Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2"	"21"	"11"	"26"	"11"	"522"	"56.0"	"8.78"	"4844.42"	"35.47"	"10"	"9"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00415"	"55920"	"ENSG00000179051; ENSG00000281540"	"RCC2"	"hsa:55920; Q8IVL9; Q9BSN6; Q9NPV8; Q9P258"	""	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"6"	"0"	"621.6"	"1160.8"	"1211.0"	"526.4"	"1211.6"	"697.4"	"4704.3"	"3081.2"	"3572.2"	"4766.8"	"6733.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55196"	"Afadin OS=Homo sapiens OX=9606 GN=AFDN PE=1 SV=3"	"6"	"7"	"17"	"7"	"1824"	"206.7"	"6.47"	"2530.78"	"35.46"	"5"	"7"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00498, Pf00595, Pf00788, Pf01843"	"4301"	"ENSG00000130396"	"AFDN"	"hsa:4301; O75087; O75088; O75089; P55196; Q59FP0; Q5TIG6; Q5TIG7; Q9NSN7; Q9NU92"	"VEGFA-VEGFR2 signaling; Ras signaling; 1q21.1 copy number variation syndrome"	""	"3"	"0"	"188.8"	"347.2"	"377.6"	"157.7"	"378.9"	"179.4"	"492.0"	"419.8"	"826.5"	"1406.4"	"2515.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14737"	"Programmed cell death protein 5 OS=Homo sapiens OX=9606 GN=PDCD5 PE=1 SV=3"	"49"	"7"	"24"	"7"	"125"	"14.3"	"6.04"	"4086.68"	"35.44"	"6"	"6"	"other biological processes"	"cytosol;nucleus"	"enzyme regulator activity;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf01984"	"9141"	"ENSG00000105185"	"PDCD5"	"B4DE64; hsa:9141; O14737; Q53YC9; Q6IB70"	""	""	"0"	"0"	"1411.2"	"1937.8"	"2034.3"	"1088.5"	"1949.9"	"1174.8"	"1676.5"	"1489.8"	"1948.9"	"2117.5"	"2585.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P40429"	"60S ribosomal protein L13a OS=Homo sapiens OX=9606 GN=RPL13A PE=1 SV=2"	"36"	"9"	"25"	"9"	"203"	"23.6"	"10.93"	"4189.88"	"35.40"	"8"	"8"	"protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00572"	"23521"	"ENSG00000142541"	"RPL13A"	"A8K505; hsa:23521; P40429"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis"	"15"	"0"	"716.7"	"1528.0"	"1448.7"	"594.6"	"1363.8"	"665.4"	"2007.5"	"1522.4"	"1999.5"	"2558.6"	"3905.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51991"	"Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2"	"32"	"8"	"20"	"7"	"378"	"39.6"	"9.01"	"2786.96"	"35.40"	"5"	"8"	"RNA metabolism OR transcription;other metabolic processes;transport"	"nucleus;other cell component"	"transporter activity;nucleic acid binding activity"	"Pf00076"	"220988"	"ENSG00000170144"	"HNRNPA3"	"D3DPF4; hsa:220988; P51991; Q53RW7; Q6URK5"	""	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"2"	"0"	"312.8"	"844.9"	"726.6"	"297.3"	"630.3"	"301.6"	"597.6"	"458.2"	"630.9"	"736.2"	"1158.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75369"	"Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2"	"5"	"9"	"17"	"9"	"2602"	"278.0"	"5.73"	"2970.05"	"35.39"	"8"	"9"	"cell organization and biogenesis;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00630"	"2317"	"ENSG00000136068"	"FLNB"	"B2ZZ83; B2ZZ84; B2ZZ85; C9JKE6; C9JMC4; hsa:2317; O75369; Q13706; Q59EC2; Q60FE7; Q6MZJ1; Q8WXS9; Q8WXT0; Q8WXT1; Q8WXT2; Q8WXT3; Q9NRB5; Q9NT26; Q9UEV9"	"Focal adhesion; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Ebola virus infection in host"	"ISG15 antiviral mechanism"	"5"	"0"	"262.0"	"851.8"	"767.6"	"202.0"	"763.6"	"275.5"	"502.7"	"418.6"	"560.7"	"677.0"	"1146.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q04637"	"Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4"	"6"	"8"	"22"	"7"	"1599"	"175.4"	"5.33"	"3961.92"	"35.28"	"8"	"8"	"protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02020, Pf02847, Pf02854"	"1981"	"ENSG00000114867"	"EIF4G1"	"D3DNT2; D3DNT4; D3DNT5; E9PFM1; G5E9S1; hsa:1981; O43177; O95066; Q04637; Q5HYG0; Q6ZN21; Q8N102"	"Translation factors; VEGFA-VEGFR2 signaling; Acute viral myocarditis; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Pleural mesothelioma"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); AUF1 (hnRNP D0) binds and destabilizes mRNA; Deadenylation of mRNA; ISG15 antiviral mechanism; mTORC1-mediated signalling"	"18"	"1"	"369.6"	"1101.5"	"991.0"	"376.6"	"898.1"	"432.5"	"862.3"	"601.3"	"858.8"	"1072.3"	"1587.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23528"	"Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3"	"75"	"14"	"27"	"13"	"166"	"18.5"	"8.09"	"5636.66"	"34.92"	"13"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf00241"	"1072"	"ENSG00000172757"	"CFL1"	"B3KUQ1; hsa:1072; P23528; Q53Y87; Q9UCA2"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; VEGFA-VEGFR2 signaling; EGF/EGFR signaling pathway; Envelope proteins and their potential roles in EDMD physiopathology; 7q11.23 copy number variation syndrome; Neuroinflammation and glutamatergic signaling; CCL18 signaling pathway; Regulation of actin cytoskeleton; G13 signaling pathway"	"Regulation of actin dynamics for phagocytic cup formation; EPHB-mediated forward signaling; Platelet degranulation ; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Sema3A PAK dependent Axon repulsion; RHO GTPases Activate ROCKs"	"15"	"2"	"776.4"	"6250.5"	"5155.5"	"435.2"	"4315.7"	"1259.5"	"1374.2"	"891.4"	"1419.3"	"1777.2"	"4306.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15366"	"Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1"	"23"	"7"	"20"	"3"	"365"	"38.6"	"6.79"	"4066.65"	"34.76"	"7"	"7"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013"	"5094"	"ENSG00000197111"	"PCBP2"	"A8K7X6; B4DXP5; F8VYL7; G3V0E8; hsa:5094; I6L8F9; Q15366; Q32Q82; Q59HD4; Q68Y55; Q6IPF4; Q6PKG5"	"mRNA processing; Ferroptosis; Modulators of TCR signaling and T cell activation"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA; Negative regulators of DDX58/IFIH1 signaling; SARS-CoV-1 activates/modulates innate immune responses"	"7"	"0"	"200.6"	"1221.6"	"897.4"	"106.8"	"638.3"	"176.9"	"337.5"	"329.0"	"484.5"	"694.4"	"1242.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95347"	"Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2"	"10"	"11"	"21"	"11"	"1197"	"135.6"	"8.43"	"3457.84"	"34.69"	"9"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02463, Pf06470"	"10592"	"ENSG00000136824"	"SMC2"	"hsa:10592; O95347; Q6IEE0; Q9P1P2"	"Retinoblastoma gene in cancer"	"Condensation of Prophase Chromosomes; Condensation of Prometaphase Chromosomes"	"3"	"0"	"382.2"	"750.4"	"848.6"	"387.8"	"865.5"	"497.1"	"1351.7"	"1054.1"	"1482.5"	"2150.9"	"3063.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P15880"	"40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2"	"35"	"10"	"25"	"10"	"293"	"31.3"	"10.24"	"5073.43"	"34.57"	"10"	"7"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00333, Pf03719"	"6187"	"ENSG00000140988"	"RPS2"	"B2R5G0; D3DU82; hsa:6187; P15880; Q3MIB1"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol; Protein methylation; Peptide chain elongation; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; RMTs methylate histone arginines; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"22"	"0"	"994.5"	"2775.4"	"2465.9"	"934.4"	"1979.7"	"1035.9"	"2945.8"	"2429.7"	"3148.5"	"4422.0"	"7327.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96CT7"	"Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1"	"33"	"10"	"22"	"10"	"223"	"25.8"	"9.54"	"3701.80"	"34.48"	"10"	"9"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf06244"	"115098"	"ENSG00000007080"	"CCDC124"	"hsa:115098; Q96CT7"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"1123.0"	"1861.0"	"2050.4"	"971.2"	"2026.5"	"1134.3"	"2530.6"	"2014.8"	"2911.7"	"3478.3"	"4688.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UHR4"	"Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 OS=Homo sapiens OX=9606 GN=BAIAP2L1 PE=1 SV=2"	"22"	"8"	"16"	"8"	"511"	"56.8"	"8.68"	"2705.82"	"34.24"	"6"	"8"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus"	"cytoskeletal activity;other molecular function"	"Pf08397, Pf14604"	"55971"	"ENSG00000006453"	"BAIAP2L1"	"A4D268; hsa:55971; Q75L21; Q75L22; Q96CV4; Q9H5F5; Q9UHR4; Q9Y2M8"	""	"RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOF GTPase cycle"	"4"	"0"	"106.5"	"167.1"	"204.2"	"81.7"	"180.8"	"111.5"	"334.0"	"281.0"	"688.6"	"1076.9"	"1487.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15355"	"Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1"	"23"	"11"	"22"	"11"	"546"	"59.2"	"4.36"	"3389.94"	"34.19"	"9"	"11"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf00481"	"5496"	"ENSG00000115241"	"PPM1G"	"hsa:5496; O15355"	"VEGFA-VEGFR2 signaling; mRNA processing"	""	"2"	"0"	"503.0"	"1127.7"	"1213.9"	"453.1"	"1181.8"	"571.8"	"1829.0"	"1322.5"	"1845.1"	"1977.8"	"2697.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61604"	"10 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPE1 PE=1 SV=2"	"81"	"11"	"29"	"11"	"102"	"10.9"	"8.92"	"5471.40"	"34.06"	"10"	"10"	"stress response;other biological processes"	"mitochondrion"	"other molecular function"	"Pf00166"	"3336"	"ENSG00000115541"	"HSPE1"	"hsa:3336; O95421; P61604; Q04984; Q53X54; Q9UDH0"	""	"RHOG GTPase cycle"	"1"	"0"	"775.7"	"3848.8"	"3435.2"	"510.4"	"2993.8"	"893.8"	"1965.1"	"2478.9"	"2816.3"	"3041.9"	"6650.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13667"	"Protein disulfide-isomerase A4 OS=Homo sapiens OX=9606 GN=PDIA4 PE=1 SV=2"	"24"	"13"	"21"	"13"	"645"	"72.9"	"5.07"	"3884.22"	"34.06"	"11"	"10"	"stress response;transport;other biological processes"	"non-structural extracellular;ER/Golgi;other cell component"	"other molecular function"	"Pf00085, Pf13848"	"9601"	"ENSG00000155660"	"PDIA4"	"A8K4K6; hsa:9601; P13667; Q549T6"	""	""	"0"	"0"	"500.3"	"2156.8"	"2015.2"	"455.7"	"1661.1"	"649.2"	"1320.7"	"988.0"	"1383.3"	"1696.8"	"3349.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62750"	"60S ribosomal protein L23a OS=Homo sapiens OX=9606 GN=RPL23A PE=1 SV=1"	"45"	"9"	"26"	"9"	"156"	"17.7"	"10.45"	"5277.18"	"33.92"	"9"	"6"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00276, Pf03939"	"6147"	"ENSG00000198242"	"RPL23A"	"B2R5B2; hsa:6147; P29316; P39024; P62750; Q92774"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"1008.1"	"2427.8"	"2293.3"	"904.5"	"2009.9"	"1083.8"	"3342.0"	"2821.4"	"3758.0"	"4549.5"	"7417.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BRG1"	"Vacuolar protein-sorting-associated protein 25 OS=Homo sapiens OX=9606 GN=VPS25 PE=1 SV=1"	"48"	"9"	"21"	"9"	"176"	"20.7"	"6.34"	"6081.84"	"33.91"	"9"	"6"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf05871"	"84313"	"ENSG00000131475"	"VPS25"	"B2R581; hsa:84313; Q9BRG1"	""	"HCMV Late Events; Endosomal Sorting Complex Required For Transport (ESCRT)"	"2"	"0"	"122.9"	"361.9"	"367.7"	"128.8"	"330.1"	"169.6"	"467.3"	"692.8"	"1074.5"	"1498.4"	"2469.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12905"	"Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2"	"21"	"6"	"13"	"6"	"390"	"43.0"	"5.26"	"2566.04"	"33.53"	"5"	"6"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf07528"	"3608"	"ENSG00000143621"	"ILF2"	"A6NDB0; B2R8G7; hsa:3608; Q12905; Q5SR10; Q5SR11; Q7L7R3; Q9BWD4; Q9P1N0"	"B cell receptor signaling pathway"	"Neutrophil degranulation"	"2"	"0"	"298.5"	"720.6"	"690.5"	"295.4"	"664.2"	"337.4"	"744.1"	"541.9"	"753.4"	"926.4"	"1345.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31943"	"Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4"	"20"	"8"	"21"	"2"	"449"	"49.2"	"6.30"	"3211.96"	"33.35"	"6"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08080"	"3187"	"ENSG00000169045; ENSG00000284254"	"HNRNPH1"	"B3KW86; D3DWQ2; hsa:3187; P31943; Q6IBM4"	"MECP2 and associated Rett syndrome; mRNA processing; Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells"	"mRNA Splicing - Major Pathway; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA"	"6"	"5"	"273.0"	"865.7"	"727.4"	"225.1"	"636.5"	"290.8"	"500.9"	"440.5"	"601.2"	"873.4"	"1489.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q09028"	"Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3"	"29"	"11"	"20"	"5"	"425"	"47.6"	"4.89"	"3393.98"	"33.32"	"10"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400, Pf12265"	"5928"	"ENSG00000162521"	"RBBP4"	"B2R6G9; B4DRH0; D3DPQ3; hsa:5928; P31149; Q09028; Q53H02; Q96BV9"	"Retinoblastoma gene in cancer; Interactome of polycomb repressive complex 2 (PRC2) ; Tumor suppressor activity of SMARCB1; Epithelial to mesenchymal transition in colorectal cancer; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; Pleural mesothelioma; DYRK1A involvement regarding cell proliferation in brain development"	"HCMV Early Events; RNA Polymerase I Transcription Initiation; Potential therapeutics for SARS; Deposition of new CENPA-containing nucleosomes at the centromere; Oxidative Stress Induced Senescence; HDACs deacetylate histones; Activation of anterior HOX genes in hindbrain development during early embryogenesis; PRC2 methylates histones and DNA; Defective pyroptosis; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6; PKMTs methylate histone lysines; G1/S-Specific Transcription; Regulation of TP53 Activity through Acetylation; Polo-like kinase mediated events; Cyclin E associated events during G1/S transition ; Transcription of E2F targets under negative control by DREAM complex; Cyclin A:Cdk2-associated events at S phase entry; Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"	"28"	"7"	"530.8"	"1432.0"	"1494.7"	"495.3"	"1321.2"	"577.3"	"1374.2"	"1169.8"	"1463.2"	"1691.8"	"2556.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01844"	"RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1"	"13"	"6"	"16"	"6"	"656"	"68.4"	"9.33"	"2374.35"	"33.24"	"3"	"6"	"RNA metabolism OR transcription;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00076, Pf00641"	"2130"	"ENSG00000182944"	"EWSR1"	"B0QYK1; hsa:2130; Q01844; Q5THL0; Q92635; Q96FE8; Q96MN4; Q96MX4; Q9BWA2"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"631.7"	"990.1"	"988.5"	"507.3"	"955.1"	"718.8"	"1693.6"	"1334.3"	"1816.7"	"2129.5"	"2767.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P32119"	"Peroxiredoxin-2 OS=Homo sapiens OX=9606 GN=PRDX2 PE=1 SV=5"	"24"	"6"	"22"	"5"	"198"	"21.9"	"5.97"	"4658.91"	"33.16"	"6"	"6"	"cell cycle OR cell proliferation;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00578, Pf10417"	"7001"	"ENSG00000167815"	"PRDX2"	"A8K0C0; hsa:7001; P31945; P32118; P32119; P35701; Q6FHG4; Q92763; Q9UC23"	"Selenium micronutrient network; VEGFA-VEGFR2 signaling"	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models; Detoxification of Reactive Oxygen Species; TP53 Regulates Metabolic Genes"	"5"	"0"	"286.3"	"1170.7"	"954.9"	"149.0"	"725.2"	"339.3"	"624.0"	"518.5"	"706.7"	"900.1"	"1669.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P12236"	"ADP/ATP translocase 3 OS=Homo sapiens OX=9606 GN=SLC25A6 PE=1 SV=4"	"28"	"9"	"22"	"2"	"298"	"32.8"	"9.74"	"3493.95"	"32.88"	"8"	"9"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity"	"Pf00153"	"293"	"ENSG00000169100"	"SLC25A6"	"hsa:293; P12236; Q96C49"	"Electron transport chain: OXPHOS system in mitochondria; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Mitochondrial protein import; Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane; Influenza Virus Induced Apoptosis; Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization"	"7"	"0"	"123.1"	"392.1"	"343.7"	"107.2"	"276.3"	"144.3"	"205.8"	"134.9"	"205.0"	"292.4"	"509.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15365"	"Poly(rC)-binding protein 1 OS=Homo sapiens OX=9606 GN=PCBP1 PE=1 SV=2"	"33"	"9"	"18"	"5"	"356"	"37.5"	"7.09"	"3147.11"	"32.86"	"7"	"9"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013"	"5093"	"ENSG00000169564"	"PCBP1"	"hsa:5093; Q13157; Q14975; Q15365"	"Ferroptosis"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"3"	"4"	"541.8"	"2481.2"	"1859.6"	"345.0"	"1461.7"	"551.4"	"814.4"	"618.1"	"960.9"	"1403.8"	"2505.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15283"	"Ras GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=RASA2 PE=1 SV=3"	"12"	"12"	"22"	"12"	"850"	"96.6"	"7.20"	"2982.76"	"32.84"	"9"	"11"	"signal transduction;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00168, Pf00169, Pf00616, Pf00779"	"5922"	"ENSG00000155903"	"RASA2"	"A8K7K1; G3V0F9; hsa:5922; O00695; Q15283; Q15284; Q92594; Q99577; Q9UEQ2"	"MAPK signaling pathway; Ebola virus infection in host; Ras signaling; Modulators of TCR signaling and T cell activation"	"Regulation of RAS by GAPs"	"5"	"0"	"263.2"	"679.9"	"665.0"	"252.3"	"631.2"	"355.4"	"1148.1"	"1738.5"	"3239.8"	"4264.0"	"6082.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P42167"	"Lamina-associated polypeptide 2, isoforms beta/gamma OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2"	"31"	"10"	"18"	"10"	"454"	"50.6"	"9.38"	"3059.04"	"32.68"	"8"	"9"	""	"other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03020, Pf08198"	"7112"	"ENSG00000120802"	"TMPO"	"A2T926; hsa:7112; P42167; Q14861"	"Envelope proteins and their potential roles in EDMD physiopathology; Overlap between signal transduction pathways contributing to LMNA laminopathies"	"RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOD GTPase cycle; RHOJ GTPase cycle; RHOF GTPase cycle"	"12"	"0"	"545.8"	"1498.9"	"1339.3"	"462.9"	"1279.0"	"575.2"	"989.8"	"789.2"	"1110.2"	"1416.5"	"2323.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UHD8"	"Septin-9 OS=Homo sapiens OX=9606 GN=SEPTIN9 PE=1 SV=2"	"19"	"9"	"18"	"9"	"586"	"65.4"	"8.97"	"3496.93"	"32.51"	"9"	"9"	"cell cycle OR cell proliferation;other biological processes"	"cytoskeleton;other cell component"	"other molecular function"	"Pf00735"	"10801"	"ENSG00000184640"	"SEPTIN9"	"A8K2V3; B3KPM0; B4DTL9; B4E0N2; B4E274; B7Z654; hsa:10801; Q96QF3; Q96QF4; Q96QF5; Q9HA04; Q9UG40; Q9UHD8; Q9Y5W4"	""	""	"0"	"0"	"429.5"	"755.4"	"867.9"	"408.4"	"800.6"	"521.5"	"1792.0"	"1255.1"	"2063.3"	"2426.1"	"3304.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35268"	"60S ribosomal protein L22 OS=Homo sapiens OX=9606 GN=RPL22 PE=1 SV=2"	"61"	"5"	"12"	"5"	"128"	"14.8"	"9.19"	"1497.59"	"32.27"	"3"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01776"	"6146"	"ENSG00000116251"	"RPL22"	"B2R495; hsa:6146; P35268; Q6IBD1"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"224.4"	"530.5"	"490.9"	"186.9"	"440.6"	"223.0"	"586.9"	"496.1"	"693.7"	"1008.5"	"1749.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92598"	"Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1"	"15"	"12"	"22"	"11"	"858"	"96.8"	"5.39"	"3488.54"	"32.25"	"10"	"10"	"stress response;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00012"	"10808"	"ENSG00000120694"	"HSPH1"	"B4DYH1; hsa:10808; O95739; Q5TBM6; Q5TBM7; Q5TBM8; Q92598; Q9UPC4"	""	"Regulation of HSF1-mediated heat shock response; Scavenging by Class F Receptors"	"2"	"0"	"622.6"	"1629.3"	"1541.4"	"511.8"	"1560.5"	"737.4"	"972.4"	"762.5"	"1133.0"	"1539.2"	"2434.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46063"	"ATP-dependent DNA helicase Q1 OS=Homo sapiens OX=9606 GN=RECQL PE=1 SV=3"	"16"	"8"	"21"	"8"	"649"	"73.4"	"7.88"	"4059.25"	"32.25"	"8"	"8"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf16124"	"5965"	"ENSG00000004700"	"RECQL"	"A8K6G2; hsa:5965; P46063"	"Progeria-associated lipodystrophy"	""	"1"	"0"	"196.1"	"430.5"	"411.0"	"179.8"	"379.1"	"217.5"	"608.9"	"439.4"	"605.4"	"722.2"	"1004.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09651"	"Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5"	"12"	"5"	"25"	"4"	"372"	"38.7"	"9.13"	"4277.81"	"32.16"	"5"	"4"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf11627"	"3178"	"ENSG00000135486"	"HNRNPA1"	"A8K4Z8; hsa:3178; P09651; Q3MIB7; Q6PJZ7"	"mRNA processing"	"mRNA Splicing - Major Pathway; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA; SARS-CoV-1-host interactions; SARS-CoV-1 modulates host translation machinery"	"6"	"0"	"609.9"	"1417.4"	"1150.2"	"491.9"	"1089.4"	"528.5"	"1452.8"	"1346.0"	"1637.8"	"1954.2"	"2631.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P17844"	"Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1"	"17"	"11"	"21"	"6"	"614"	"69.1"	"8.92"	"3499.78"	"31.95"	"9"	"10"	"RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf08061"	"1655"	"ENSG00000108654"	"DDX5"	"B4DLW8; B5BU21; D3DU32; E7ETL9; hsa:1655; O75681; P17844; Q53Y61"	"Ciliary landscape"	"mRNA Splicing - Major Pathway; SUMOylation of transcription cofactors; Estrogen-dependent gene expression; Replication of the SARS-CoV-1 genome; Replication of the SARS-CoV-2 genome"	"6"	"0"	"571.3"	"1254.2"	"1278.6"	"504.6"	"1164.1"	"642.4"	"1276.0"	"905.6"	"1318.6"	"1617.4"	"2587.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62979"	"Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2"	"56"	"8"	"17"	"8"	"156"	"18.0"	"9.64"	"2726.80"	"31.84"	"6"	"7"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;translational apparatus;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00240, Pf01599"	"6233"	"ENSG00000143947"	"RPS27A"	"hsa:6233; P02248; P02249; P02250; P14798; P62979; P62988; Q29120; Q6LBL4; Q6LDU5; Q8WYN8; Q91887; Q91888; Q9BQ77; Q9BWD6; Q9BX98; Q9UEF2; Q9UEG1; Q9UEK8; Q9UPK7"	"Cytoplasmic ribosomal proteins"	"Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Aggrephagy; Oxidative Stress Induced Senescence; ISG15 antiviral mechanism; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; InlA-mediated entry of Listeria monocytogenes into host cells; ER-Phagosome pathway; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Orc1 removal from chromatin; Assembly of the pre-replicative complex; Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; Recognition of DNA damage by PCNA-containing replication complex; Dual Incision in GG-NER; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER; Peroxisomal protein import; Degradation of GLI1 by the proteasome; Hedgehog 'on' state; Activated NOTCH1 Transmits Signal to the Nucleus; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Regulation of PLK1 Activity at G2/M Transition; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery; E3 ubiquitin ligases ubiquitinate target proteins; Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Stimuli-sensing channels; Amyloid fiber formation; Fanconi Anemia Pathway; Budding and maturation of HIV virion; Membrane binding and targetting of GAG proteins; Endosomal Sorting Complex Required For Transport (ESCRT); Late endosomal microautophagy; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; NOTCH2 Activation and Transmission of Signal to the Nucleus; NOTCH3 Activation and Transmission of Signal to the Nucleus; Regulation of TP53 Degradation; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Activation of IRF3, IRF7 mediated by TBK1, IKBKE; IKK complex recruitment mediated by RIP1; TRAF6-mediated induction of TAK1 complex within TLR4 complex; IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation; ER Quality Control Compartment (ERQC); SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Deactivation of the beta-catenin transactivating complex; Circadian Clock; Regulation of signaling by CBL; Metalloprotease DUBs; Regulation of necroptotic cell death; Oncogene Induced Senescence; Cyclin D associated events in G1; APC/C:Cdc20 mediated degradation of Cyclin B; APC-Cdc20 mediated degradation of Nek2A; Senescence-Associated Secretory Phenotype (SASP); Negative regulation of FLT3; Downregulation of ERBB2:ERBB3 signaling; Cargo recognition for clathrin-mediated endocytosis; Interferon alpha/beta signaling; Inactivation of CSF3 (G-CSF) signaling; JNK (c-Jun kinases) phosphorylation and  activation mediated by activated human TAK1; Regulation of TP53 Activity through Methylation; Regulation of BACH1 activity; NOD1/2 Signaling Pathway; TICAM1, RIP1-mediated IKK complex recruitment; p75NTR recruits signalling complexes; NF-kB is activated and signals survival; TAK1-dependent IKK and NF-kappa-B activation  ; Regulation of TNFR1 signaling; TNFR1-induced NF-kappa-B signaling pathway; MAP3K8 (TPL2)-dependent MAPK1/3 activation; IRAK1 recruits IKK complex; IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation; Regulation of NF-kappa B signaling; Negative regulators of DDX58/IFIH1 signaling; EGFR downregulation; Negative regulation of MET activity; InlB-mediated entry of Listeria monocytogenes into host cell; Prevention of phagosomal-lysosomal fusion; Downregulation of TGF-beta receptor signaling; Downregulation of SMAD2/3:SMAD4 transcriptional activity; Signaling by CSF1 (M-CSF) in myeloid cells; NOTCH1 Intracellular Domain Regulates Transcription; TICAM1-dependent activation of IRF3/IRF7; TICAM1,TRAF6-dependent induction of TAK1 complex; Glycogen synthesis; Formation of TC-NER Pre-Incision Complex; Modulation by Mtb of host immune system; activated TAK1 mediates p38 MAPK activation; IRAK2 mediated activation of TAK1 complex; SARS-CoV-1 activates/modulates innate immune responses; Alpha-protein kinase 1 signaling pathway; Ovarian tumor domain proteases; Spry regulation of FGF signaling; RAS processing; PINK1-PRKN Mediated Mitophagy; Josephin domain DUBs; Regulation of FZD by ubiquitination; Chaperone Mediated Autophagy; Formation of Incision Complex in GG-NER; Iron uptake and transport; VLDLR internalisation and degradation; Myoclonic epilepsy of Lafora; DNA Damage Recognition in GG-NER; Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; Negative regulation of MAPK pathway; TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition); NRIF signals cell death from the nucleus; Assembly Of The HIV Virion; Downregulation of ERBB4 signaling; Regulation of innate immune responses to cytosolic DNA; N-glycan trimming in the ER and Calnexin/Calreticulin cycle; PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1; Regulation of PTEN localization; Pexophagy; Maturation of protein E; Maturation of protein E; FLT3 signaling by CBL mutants; TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling"	"201"	"0"	"1497.0"	"3910.3"	"3804.1"	"1110.8"	"3264.7"	"1953.0"	"2986.9"	"2106.1"	"2933.0"	"3207.4"	"5022.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95433"	"Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1"	"25"	"9"	"19"	"9"	"338"	"38.3"	"5.53"	"2931.66"	"31.83"	"7"	"9"	"other biological processes"	"cytosol;ER/Golgi"	"other molecular function"	"Pf08327, Pf09229"	"10598"	"ENSG00000100591"	"AHSA1"	"B2R9L2; B4DUR9; hsa:10598; O95433; Q96IL6; Q9P060"	"T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection"	""	"1"	"0"	"1564.8"	"1807.8"	"1950.5"	"1194.6"	"1628.4"	"1182.5"	"1905.1"	"1516.9"	"1797.2"	"1925.5"	"1966.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P38159"	"RNA-binding motif protein, X chromosome OS=Homo sapiens OX=9606 GN=RBMX PE=1 SV=3"	"15"	"5"	"18"	"5"	"391"	"42.3"	"10.05"	"3717.63"	"31.81"	"5"	"5"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08081"	"27316"	"ENSG00000147274"	"RBMX"	"B4E3U4; D3DWH0; E9PG86; hsa:27316; P38159; Q5JQ67; Q8N8Y7; Q969R3"	"mRNA processing"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA; RND2 GTPase cycle; RND3 GTPase cycle; RND1 GTPase cycle; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle"	"8"	"0"	"561.0"	"1391.5"	"1288.3"	"465.1"	"1213.3"	"607.3"	"1566.1"	"1192.4"	"1630.2"	"1919.6"	"2766.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P39687"	"Acidic leucine-rich nuclear phosphoprotein 32 family member A OS=Homo sapiens OX=9606 GN=ANP32A PE=1 SV=1"	"29"	"9"	"18"	"6"	"249"	"28.6"	"4.09"	"2942.91"	"31.40"	"8"	"7"	"transport;signal transduction;other biological processes"	"ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf14580"	"8125"	"ENSG00000140350"	"ANP32A"	"B2R6T4; hsa:8125; P39687; Q53FK4; Q5J8L8; Q7M4N6"	"IL-18 signaling pathway"	"HuR (ELAVL1) binds and stabilizes mRNA"	"2"	"0"	"383.0"	"1039.8"	"974.2"	"307.8"	"916.3"	"448.0"	"797.6"	"681.2"	"793.7"	"1070.9"	"1808.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13263"	"Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5"	"12"	"9"	"19"	"9"	"835"	"88.5"	"5.77"	"3893.71"	"31.40"	"8"	"8"	"cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00628, Pf00643, Pf14634"	"10155"	"ENSG00000130726"	"TRIM28"	"hsa:10155; O00677; Q13263; Q7Z632; Q93040; Q96IM1"	"Corticotropin-releasing hormone signaling pathway; Mesodermal commitment pathway; ATM signaling in development and disease"	"Generic Transcription Pathway; HCMV Early Events; SUMOylation of transcription cofactors"	"6"	"0"	"496.9"	"2171.1"	"1765.0"	"426.1"	"1553.6"	"650.9"	"926.6"	"723.1"	"1030.6"	"1303.8"	"2206.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P2J5"	"Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2"	"8"	"9"	"22"	"9"	"1176"	"134.4"	"7.30"	"3256.09"	"31.36"	"7"	"9"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00133, Pf08264"	"51520"	"ENSG00000133706"	"LARS1"	"A2RRR4; A7E266; B4DJ10; hsa:51520; Q2TU79; Q9NSE1; Q9P2J5"	""	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"2"	"0"	"728.9"	"1764.0"	"1731.1"	"631.4"	"1536.1"	"758.4"	"1000.2"	"718.2"	"1103.6"	"1485.3"	"2293.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86YS7"	"C2 domain-containing protein 5 OS=Homo sapiens OX=9606 GN=C2CD5 PE=1 SV=1"	"10"	"9"	"16"	"9"	"1000"	"110.4"	"5.69"	"2267.97"	"31.32"	"6"	"8"	"transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00168"	"9847"	"ENSG00000111731"	"C2CD5"	"B4DJ03; B4DRN7; B7ZLL0; F5H2A1; F5H5R1; hsa:9847; O60280; Q17RY7; Q7Z619; Q86SU3; Q86YS7"	""	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"	"1"	"0"	"201.3"	"352.6"	"411.3"	"196.0"	"380.8"	"235.3"	"690.2"	"1089.4"	"1937.2"	"3039.2"	"4248.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95757"	"Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3"	"13"	"9"	"20"	"6"	"839"	"94.5"	"5.88"	"3285.09"	"31.25"	"7"	"9"	"stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00012"	"22824"	"ENSG00000164070"	"HSPA4L"	"A2ICT2; hsa:22824; O95757; Q4W5M5; Q8IWA2"	""	"Regulation of HSF1-mediated heat shock response"	"1"	"2"	"526.0"	"1270.4"	"1236.8"	"512.8"	"1142.7"	"560.2"	"1218.5"	"843.3"	"1078.7"	"1431.6"	"2190.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07910"	"Heterogeneous nuclear ribonucleoproteins C1/C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4"	"23"	"7"	"21"	"7"	"306"	"33.7"	"5.08"	"4884.29"	"31.25"	"7"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"3183"	"ENSG00000092199"	"HNRNPC"	"D3DS19; D3DS22; hsa:3183; P07910; P22628; Q53EX2; Q59FD3; Q5FWE8; Q86SF8; Q86U45; Q96HK7; Q96HM4; Q96IY5; Q9BTS3"	"mRNA processing"	"SUMOylation of RNA binding proteins; mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle"	"6"	"0"	"592.7"	"1160.8"	"1295.6"	"512.1"	"1406.2"	"663.0"	"995.7"	"594.1"	"928.0"	"1070.6"	"1606.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P39748"	"Flap endonuclease 1 OS=Homo sapiens OX=9606 GN=FEN1 PE=1 SV=1"	"24"	"9"	"18"	"9"	"380"	"42.6"	"8.62"	"3589.28"	"31.19"	"9"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00752, Pf00867"	"2237"	"ENSG00000168496"	"FEN1"	"hsa:2237; P39748"	"Base excision repair; DNA repair pathways, full network"	"HDR through MMEJ (alt-NHEJ); Early Phase of HIV Life Cycle; POLB-Dependent Long Patch Base Excision Repair; PCNA-Dependent Long Patch Base Excision Repair; Removal of the Flap Intermediate; Removal of the Flap Intermediate from the C-strand"	"8"	"0"	"270.4"	"482.1"	"561.8"	"229.4"	"514.1"	"300.2"	"1430.6"	"1045.5"	"1632.6"	"2429.4"	"3903.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46778"	"60S ribosomal protein L21 OS=Homo sapiens OX=9606 GN=RPL21 PE=1 SV=2"	"48"	"8"	"18"	"8"	"160"	"18.6"	"10.49"	"3117.48"	"31.12"	"6"	"6"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;other cell component"	"other molecular function"	"Pf01157"	"6144"	"ENSG00000122026"	"RPL21"	"hsa:6144; P46778; Q16699"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"671.7"	"1053.8"	"1105.5"	"571.3"	"1082.8"	"696.4"	"2192.2"	"1644.4"	"2052.4"	"2387.0"	"3188.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P27824"	"Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2"	"21"	"12"	"22"	"12"	"592"	"67.5"	"4.60"	"4096.95"	"31.04"	"10"	"10"	"protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;translational apparatus;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00262"	"821"	"ENSG00000127022; ENSG00000283777"	"CANX"	"B2R5V8; B4DGP8; B4E2T8; D3DWQ3; D6R9K3; hsa:821; P27824"	""	"Maturation of spike protein; MHC class II antigen presentation; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Interleukin-35 Signalling; Interleukin-27 signaling; Assembly of Viral Components at the Budding Site; Calnexin/calreticulin cycle; Maturation of spike protein"	"8"	"0"	"829.9"	"3334.2"	"3079.6"	"560.2"	"2679.7"	"1034.3"	"1139.6"	"797.3"	"1268.2"	"1578.2"	"3033.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19447"	"General transcription and DNA repair factor IIH helicase subunit XPB OS=Homo sapiens OX=9606 GN=ERCC3 PE=1 SV=1"	"13"	"9"	"17"	"9"	"782"	"89.2"	"7.23"	"1910.85"	"31.00"	"6"	"9"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04851, Pf13625, Pf16203"	"2071"	"ENSG00000163161"	"ERCC3"	"hsa:2071; P19447; Q53QM0"	"Eukaryotic transcription initiation; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; 11p11.2 copy number variation syndrome"	"Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; Formation of Incision Complex in GG-NER; Dual Incision in GG-NER"	"34"	"0"	"118.2"	"268.9"	"276.8"	"112.3"	"249.5"	"157.5"	"342.1"	"491.6"	"987.0"	"1357.1"	"1695.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62851"	"40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1"	"39"	"7"	"24"	"7"	"125"	"13.7"	"10.11"	"3984.71"	"30.92"	"7"	"6"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf03297"	"6230"	"ENSG00000118181; ENSG00000280831"	"RPS25"	"B2R4M7; hsa:6230; P25111; P62851"	"Cytoplasmic ribosomal proteins"	"Major pathway of rRNA processing in the nucleolus and cytosol; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"722.8"	"1390.7"	"1327.0"	"625.1"	"1275.4"	"733.7"	"1931.9"	"1532.1"	"1914.4"	"2464.4"	"3240.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UMS4"	"Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1"	"16"	"7"	"17"	"7"	"504"	"55.1"	"6.61"	"2193.05"	"30.78"	"6"	"7"	"cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00400, Pf04564, Pf08606"	"27339"	"ENSG00000110107"	"PRPF19"	"hsa:27339; Q9UMS4"	""	"mRNA Splicing - Major Pathway; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of TC-NER Pre-Incision Complex"	"5"	"0"	"504.9"	"960.1"	"993.7"	"406.9"	"915.9"	"552.8"	"1021.9"	"1359.8"	"1486.2"	"1697.0"	"2901.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NZI8"	"Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2"	"15"	"8"	"18"	"7"	"577"	"63.4"	"9.20"	"3341.80"	"30.59"	"7"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf00076"	"10642"	"ENSG00000159217"	"IGF2BP1"	"C9JT33; hsa:10642; Q9NZI8"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; eIF5A regulation in response to inhibition of the nuclear export system"	"MAPK6/MAPK4 signaling; Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"	"4"	"1"	"796.2"	"1794.0"	"1740.0"	"722.0"	"1613.3"	"873.6"	"1518.4"	"1051.3"	"1510.7"	"1788.3"	"2792.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2Z4"	"Tyrosine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=YARS2 PE=1 SV=2"	"15"	"7"	"17"	"7"	"477"	"53.2"	"8.98"	"3310.27"	"30.48"	"6"	"7"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00579"	"51067"	"ENSG00000139131"	"YARS2"	"D3DUW8; hsa:51067; Q9H817; Q9Y2Z4"	"Orexin receptor pathway"	"Mitochondrial tRNA aminoacylation"	"2"	"0"	"199.9"	"283.4"	"344.4"	"173.4"	"336.1"	"228.6"	"1172.6"	"860.0"	"1342.3"	"2004.7"	"3168.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75937"	"DnaJ homolog subfamily C member 8 OS=Homo sapiens OX=9606 GN=DNAJC8 PE=1 SV=2"	"20"	"6"	"14"	"6"	"253"	"29.8"	"9.06"	"2282.58"	"30.36"	"4"	"6"	""	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00226"	"22826"	"ENSG00000126698; ENSG00000285317"	"DNAJC8"	"B4DUU4; D3DPM0; hsa:22826; O75937; Q6IBA4; Q8N4Z5; Q9P051; Q9P067"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"315.9"	"529.0"	"608.0"	"298.7"	"622.5"	"343.7"	"1130.5"	"876.4"	"1476.0"	"2323.0"	"5080.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UQE7"	"Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2"	"9"	"11"	"19"	"11"	"1217"	"141.5"	"7.18"	"2893.38"	"30.19"	"8"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf02463, Pf06470"	"9126"	"ENSG00000108055"	"SMC3"	"A8K156; hsa:9126; O60464; Q5T482; Q9UQE7"	"Cell cycle; Retinoblastoma gene in cancer; MECP2 and associated Rett syndrome; Prion disease pathway; Regulation of sister chromatid separation at the metaphase-anaphase transition; Cohesin complex - Cornelia de Lange syndrome; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Meiotic synapsis; Estrogen-dependent gene expression; SUMOylation of DNA damage response and repair proteins; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"14"	"0"	"510.1"	"989.2"	"1089.9"	"486.8"	"1017.7"	"591.0"	"1220.8"	"947.6"	"1453.8"	"2113.7"	"3231.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2L1"	"Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2"	"11"	"10"	"18"	"10"	"958"	"108.9"	"7.14"	"3110.17"	"30.12"	"8"	"9"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00773, Pf13638, Pf17215, Pf17216, Pf17849"	"22894"	"ENSG00000083520"	"DIS3"	"A6NI21; B2RBL2; hsa:22894; Q5W0P7; Q5W0P8; Q658Z7; Q7Z481; Q8WWI2; Q9UG36; Q9Y2L1"	""	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; Major pathway of rRNA processing in the nucleolus and cytosol; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	"6"	"0"	"633.3"	"1337.7"	"1286.6"	"551.5"	"1300.6"	"654.8"	"1179.8"	"901.5"	"1232.6"	"1741.3"	"2426.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92688"	"Acidic leucine-rich nuclear phosphoprotein 32 family member B OS=Homo sapiens OX=9606 GN=ANP32B PE=1 SV=1"	"28"	"9"	"17"	"6"	"251"	"28.8"	"4.06"	"2472.54"	"29.96"	"7"	"7"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf12799"	"10541"	"ENSG00000136938"	"ANP32B"	"B2R9C7; hsa:10541; O00655; P78458; P78459; Q92688"	""	""	"0"	"3"	"501.9"	"1646.6"	"1609.8"	"507.4"	"1384.0"	"718.0"	"1685.9"	"1396.5"	"1588.9"	"1723.0"	"2837.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62277"	"40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2"	"62"	"11"	"23"	"11"	"151"	"17.2"	"10.54"	"3748.09"	"29.91"	"9"	"9"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00312, Pf08069"	"6207"	"ENSG00000110700"	"RPS13"	"B2R549; hsa:6207; P19116; P62277; Q02546; Q29200; Q498Y0"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Selenocysteine synthesis; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"879.6"	"2142.3"	"2409.3"	"854.8"	"1907.7"	"881.4"	"2088.0"	"1789.9"	"2457.1"	"3538.0"	"5479.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13642"	"Four and a half LIM domains protein 1 OS=Homo sapiens OX=9606 GN=FHL1 PE=1 SV=4"	"22"	"6"	"13"	"6"	"323"	"36.2"	"8.97"	"2307.07"	"29.84"	"4"	"5"	"other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00412"	"2273"	"ENSG00000022267"	"FHL1"	"B7Z5T4; B7Z793; hsa:2273; O95212; Q13230; Q13642; Q13645; Q5JXI7; Q5M7Y6; Q6IB30; Q9NZ40; Q9UKZ8; Q9Y630"	"Notch signaling pathway"	""	"1"	"0"	"639.1"	"1115.7"	"1153.0"	"513.5"	"994.7"	"557.5"	"1026.6"	"864.1"	"1148.9"	"1325.0"	"1960.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13347"	"Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens OX=9606 GN=EIF3I PE=1 SV=1"	"20"	"7"	"15"	"7"	"325"	"36.5"	"5.64"	"2316.07"	"29.77"	"5"	"7"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf00400"	"8668"	"ENSG00000084623"	"EIF3I"	"hsa:8668; Q13347"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition"	"8"	"0"	"808.9"	"1390.8"	"1487.9"	"731.8"	"1347.1"	"953.7"	"1255.2"	"1011.9"	"1408.9"	"1667.6"	"2666.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62829"	"60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1"	"65"	"7"	"16"	"7"	"140"	"14.9"	"10.51"	"3140.80"	"29.63"	"6"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00238"	"9349"	"ENSG00000125691"	"RPL23"	"hsa:9349; P23131; P24048; P62829; Q29246; Q3SWV7; Q6P5S1"	"Cytoplasmic ribosomal proteins; 17q12 copy number variation syndrome"	"Regulation of expression of SLITs and ROBOs; SRP-dependent cotranslational protein targeting to membrane; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"15"	"0"	"442.9"	"1026.4"	"887.6"	"420.0"	"858.8"	"463.8"	"1180.8"	"1004.1"	"1221.8"	"1536.0"	"2205.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99584"	"Protein S100-A13 OS=Homo sapiens OX=9606 GN=S100A13 PE=1 SV=1"	"40"	"4"	"17"	"4"	"98"	"11.5"	"6.16"	"2748.93"	"29.60"	"4"	"4"	"transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01023"	"6284"	"ENSG00000189171"	"S100A13"	"hsa:6284; Q52PI9; Q6FGF8; Q99584"	""	""	"0"	"0"	"372.9"	"475.8"	"681.4"	"373.5"	"656.9"	"464.8"	"742.4"	"674.8"	"1193.5"	"1777.5"	"4281.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22392"	"Nucleoside diphosphate kinase B OS=Homo sapiens OX=9606 GN=NME2 PE=1 SV=1"	"47"	"6"	"17"	"2"	"152"	"17.3"	"8.41"	"3282.41"	"29.58"	"6"	"6"	"cell adhesion;protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00334"	"4831; 654364"	"ENSG00000243678"	"NME2"	"A8MWA3; hsa:4831; hsa:654364; P22392; Q1WM23; Q6LCT6"	"Pyrimidine metabolism"	"Neutrophil degranulation; Interconversion of nucleotide di- and triphosphates; Azathioprine ADME; Ribavirin ADME"	"5"	"6"	"377.4"	"3120.2"	"2303.2"	"231.0"	"1658.5"	"488.5"	"896.9"	"688.3"	"881.0"	"1132.8"	"3053.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P53999"	"Activated RNA polymerase II transcriptional coactivator p15 OS=Homo sapiens OX=9606 GN=SUB1 PE=1 SV=3"	"39"	"5"	"17"	"5"	"127"	"14.4"	"9.60"	"3173.63"	"29.51"	"3"	"5"	"RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02229"	"10923"	"ENSG00000113387"	"SUB1"	"hsa:10923; P53999; Q96L29"	""	""	"0"	"0"	"268.2"	"382.3"	"484.9"	"227.9"	"513.1"	"332.7"	"3118.8"	"1726.8"	"1626.6"	"1826.8"	"2247.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14157"	"Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2"	"10"	"8"	"16"	"8"	"1087"	"114.5"	"7.11"	"2625.62"	"29.51"	"6"	"8"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	""	"Pf12478"	"9898"	"ENSG00000143569"	"UBAP2L"	"B4E0U8; hsa:9898; Q14157; Q5VU75; Q5VU76; Q9BTU3; Q9UGL2; Q9UGL3; Q9UGL4; Q9UGL5"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"544.0"	"869.3"	"874.2"	"448.8"	"907.0"	"525.9"	"914.0"	"722.8"	"1077.2"	"1338.9"	"1924.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62917"	"60S ribosomal protein L8 OS=Homo sapiens OX=9606 GN=RPL8 PE=1 SV=2"	"28"	"11"	"21"	"11"	"257"	"28.0"	"11.03"	"3261.01"	"29.50"	"10"	"9"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00181, Pf03947"	"6132"	"ENSG00000161016"	"RPL8"	"A8K094; D3DWN2; hsa:6132; P25120; P62917; Q567Q7; Q969V7; Q9BWQ9"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Selenocysteine synthesis; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"881.3"	"2157.5"	"2065.8"	"729.5"	"1970.7"	"804.4"	"3601.8"	"2723.6"	"3484.5"	"4701.3"	"6692.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q52LJ0"	"Protein FAM98B OS=Homo sapiens OX=9606 GN=FAM98B PE=1 SV=2"	"29"	"8"	"16"	"8"	"433"	"45.5"	"8.69"	"2310.31"	"29.48"	"6"	"8"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf10239"	"283742"	"ENSG00000171262"	"FAM98B"	"A8MUW5; hsa:283742; Q52LJ0; Q8N935"	""	"tRNA processing in the nucleus"	"1"	"0"	"643.5"	"866.7"	"1067.6"	"538.5"	"1026.6"	"701.8"	"1799.2"	"1183.0"	"1757.7"	"2027.8"	"2726.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14979"	"Heterogeneous nuclear ribonucleoprotein D-like OS=Homo sapiens OX=9606 GN=HNRNPDL PE=1 SV=3"	"19"	"6"	"18"	"4"	"420"	"46.4"	"9.57"	"3365.81"	"29.33"	"6"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity"	"Pf00076"	"9987"	"ENSG00000152795"	"HNRNPDL"	"hsa:9987; O14979; Q6SPF2; Q7KZ74; Q7KZ75; Q96IM0; Q96S43"	""	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	"1"	"0"	"143.6"	"310.6"	"305.1"	"136.3"	"295.4"	"140.3"	"255.4"	"179.1"	"271.8"	"347.0"	"506.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61254"	"60S ribosomal protein L26 OS=Homo sapiens OX=9606 GN=RPL26 PE=1 SV=1"	"34"	"9"	"27"	"1"	"145"	"17.2"	"10.55"	"5396.84"	"29.07"	"9"	"6"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00467, Pf16906"	"6154"	"ENSG00000161970"	"RPL26"	"B2R4F0; D3DTR8; hsa:6154; P61254; Q02877; Q6IPY2"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Peptide chain elongation; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"15"	"12"	"976.1"	"1854.5"	"1921.7"	"825.9"	"1790.3"	"989.4"	"3375.1"	"2563.8"	"3299.4"	"4037.0"	"5460.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P29966"	"Myristoylated alanine-rich C-kinase substrate OS=Homo sapiens OX=9606 GN=MARCKS PE=1 SV=4"	"21"	"6"	"18"	"6"	"332"	"31.5"	"4.45"	"3212.41"	"28.97"	"6"	"6"	"cell organization and biogenesis;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02063"	"4082"	"ENSG00000277443"	"MARCKS"	"E1P560; hsa:4082; P29966; Q2LA83; Q5TDB7"	"Brain-derived neurotrophic factor (BDNF) signaling pathway"	"Acetylcholine regulates insulin secretion"	"2"	"0"	"650.8"	"1287.5"	"1082.8"	"490.4"	"1008.7"	"785.0"	"836.4"	"701.0"	"892.4"	"1019.5"	"1641.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52597"	"Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3"	"19"	"7"	"15"	"5"	"415"	"45.6"	"5.58"	"2238.99"	"28.93"	"5"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf08080"	"3185"	"ENSG00000169813"	"HNRNPF"	"B3KM84; hsa:3185; P52597; Q5T0N2; Q96AU2"	"MECP2 and associated Rett syndrome"	"mRNA Splicing - Major Pathway; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA"	"5"	"0"	"440.3"	"501.6"	"550.2"	"262.8"	"532.4"	"308.6"	"436.7"	"323.3"	"472.6"	"659.6"	"907.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43390"	"Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1"	"17"	"9"	"19"	"3"	"633"	"70.9"	"8.13"	"3654.37"	"28.92"	"8"	"7"	"RNA metabolism OR transcription;other metabolic processes"	"ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf18360"	"10236"	"ENSG00000125944; ENSG00000282958"	"HNRNPR"	"hsa:10236; O43390; Q2L7G6; Q5TEH1; Q9BV64; S4R3J4"	"mRNA processing"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"3"	"0"	"153.5"	"212.2"	"233.6"	"101.1"	"289.3"	"149.8"	"321.6"	"179.2"	"313.9"	"333.5"	"430.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15029"	"116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1"	"8"	"7"	"18"	"6"	"972"	"109.4"	"5.00"	"3262.48"	"28.90"	"7"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf00679, Pf03144, Pf03764, Pf14492, Pf16004"	"9343"	"ENSG00000108883"	"EFTUD2"	"B4DK30; B4DMC0; D3DX58; hsa:9343; K7EJ81; Q15029; Q9BUR0"	"mRNA processing; Ciliary landscape"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"4"	"0"	"343.5"	"663.4"	"717.6"	"279.0"	"657.5"	"394.4"	"774.5"	"557.3"	"875.1"	"1030.1"	"1525.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96PK6"	"RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2"	"14"	"9"	"17"	"9"	"669"	"69.4"	"9.67"	"2558.58"	"28.73"	"7"	"8"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00076"	"100526737; 10432"	"ENSG00000239306"	"RBM14"	"B0LM41; B3KMN4; D6RGD8; hsa:100526737; hsa:10432; O75932; Q2PYN1; Q53GV1; Q68DQ9; Q96PK5; Q96PK6"	"Ciliary landscape"	"RUNX2 regulates bone development"	"2"	"0"	"398.5"	"612.6"	"626.6"	"328.6"	"609.0"	"364.6"	"2207.9"	"1819.7"	"2087.5"	"2460.5"	"2878.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P37108"	"Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2"	"46"	"6"	"19"	"6"	"136"	"14.6"	"10.04"	"2310.39"	"28.69"	"5"	"5"	"transport"	"non-structural extracellular;cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02290"	"6727"	"ENSG00000140319"	"SRP14"	"B5BUF5; hsa:6727; P37108; Q6B0K5; Q96Q14"	""	"Neutrophil degranulation; SRP-dependent cotranslational protein targeting to membrane"	"2"	"0"	"201.3"	"457.9"	"485.3"	"203.3"	"455.1"	"242.5"	"669.4"	"825.8"	"1678.3"	"4503.4"	"9369.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15145"	"Actin-related protein 2/3 complex subunit 3 OS=Homo sapiens OX=9606 GN=ARPC3 PE=1 SV=3"	"29"	"6"	"17"	"6"	"178"	"20.5"	"8.59"	"2660.74"	"28.67"	"4"	"6"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf04062"	"10094"	"ENSG00000111229"	"ARPC3"	"hsa:10094; O00554; O15145"	"Pathogenic Escherichia coli infection"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Clathrin-mediated endocytosis; EPHB-mediated forward signaling"	"6"	"0"	"201.9"	"367.8"	"453.9"	"207.2"	"399.0"	"225.7"	"1054.9"	"1232.4"	"1575.9"	"2653.7"	"5948.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62888"	"60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2"	"55"	"8"	"21"	"7"	"115"	"12.8"	"9.63"	"4284.74"	"28.65"	"7"	"7"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01248"	"6156"	"ENSG00000156482"	"RPL30"	"B2R591; hsa:6156; P04645; P62888; Q502Z6"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"329.3"	"750.4"	"739.9"	"327.1"	"669.0"	"359.9"	"945.6"	"637.0"	"880.6"	"1038.9"	"1585.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6PI48"	"Aspartate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=DARS2 PE=1 SV=1"	"18"	"10"	"21"	"10"	"645"	"73.5"	"8.02"	"3230.49"	"28.09"	"10"	"10"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00152, Pf01336, Pf02938"	"55157"	"ENSG00000117593"	"DARS2"	"hsa:55157; Q6PI48"	""	"Mitochondrial tRNA aminoacylation"	"1"	"0"	"312.8"	"658.0"	"791.9"	"289.5"	"674.8"	"393.9"	"1680.8"	"1165.5"	"1598.8"	"2366.1"	"3453.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A0FGR8"	"Extended synaptotagmin-2 OS=Homo sapiens OX=9606 GN=ESYT2 PE=1 SV=1"	"10"	"6"	"14"	"6"	"921"	"102.3"	"9.26"	"1698.37"	"28.01"	"4"	"6"	"cell organization and biogenesis;transport"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00168, Pf17047"	"57488"	"ENSG00000117868"	"ESYT2"	"A0FGR8; A4D229; hsa:57488; Q69YJ2; Q6UKI4; Q6ZTU0; Q6ZVU1; Q9BQS0; Q9NW47; Q9ULJ2"	""	"Glycosphingolipid metabolism"	"1"	"0"	"97.6"	"264.0"	"253.7"	"89.5"	"235.4"	"135.5"	"337.2"	"420.5"	"823.1"	"1237.5"	"2007.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q08J23"	"RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2"	"13"	"5"	"12"	"5"	"767"	"86.4"	"6.77"	"1900.63"	"27.85"	"2"	"5"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytoskeleton;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01189"	"54888"	"ENSG00000037474"	"NSUN2"	"A8K529; B2RNR4; B3KP09; B4DQW2; G3V1R4; hsa:54888; Q08J23; Q9BVN4; Q9H858; Q9NXD9"	""	"tRNA modification in the nucleus and cytosol"	"1"	"0"	"140.7"	"368.7"	"352.9"	"116.7"	"308.7"	"155.2"	"295.8"	"197.5"	"338.3"	"394.8"	"619.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WWM7"	"Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2"	"9"	"7"	"16"	"6"	"1075"	"113.3"	"8.59"	"2933.83"	"27.83"	"6"	"7"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf06741, Pf07145, Pf14438"	"11273"	"ENSG00000168488"	"ATXN2L"	"A8K1R6; B9EGM2; E9PAR9; hsa:11273; O95135; Q63ZY4; Q6NVJ8; Q6PJW6; Q8IU61; Q8IU95; Q8WWM3; Q8WWM4; Q8WWM5; Q8WWM6; Q8WWM7; Q99703"	"16p11.2 distal deletion syndrome"	""	"1"	"1"	"681.1"	"983.0"	"963.1"	"501.2"	"992.1"	"648.2"	"1359.0"	"948.6"	"1372.4"	"1522.6"	"1889.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46781"	"40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3"	"45"	"12"	"24"	"12"	"194"	"22.6"	"10.65"	"4497.06"	"27.79"	"11"	"9"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00163, Pf01479"	"6203"	"ENSG00000170889; ENSG00000274005; ENSG00000274626; ENSG00000274646; ENSG00000274950; ENSG00000275323; ENSG00000277079; ENSG00000277359; ENSG00000278081; ENSG00000278270"	"RPS9"	"A9C4C1; hsa:6203; P46781; Q4QRK7; Q9BVZ0"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol; Peptide chain elongation; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"20"	"0"	"526.1"	"1740.9"	"1832.3"	"538.2"	"1432.4"	"602.8"	"1521.9"	"1252.5"	"1708.8"	"2699.0"	"3886.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P10515"	"Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3"	"14"	"8"	"14"	"8"	"647"	"69.0"	"7.84"	"2015.28"	"27.78"	"5"	"8"	"other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf00198, Pf00364, Pf02817"	"1737"	"ENSG00000150768"	"DLAT"	"hsa:1737; P10515; Q16783; Q53EP3"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Neuroinflammation and glutamatergic signaling; Glycolysis and gluconeogenesis"	"Glyoxylate metabolism and glycine degradation; Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid"	"7"	"0"	"1202.6"	"1880.3"	"2050.4"	"1215.7"	"1773.1"	"1403.1"	"533.9"	"397.2"	"641.7"	"765.5"	"1252.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23193"	"Transcription elongation factor A protein 1 OS=Homo sapiens OX=9606 GN=TCEA1 PE=1 SV=2"	"29"	"8"	"24"	"8"	"301"	"33.9"	"8.38"	"2560.67"	"27.75"	"6"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01096, Pf07500, Pf08711"	"6917"	"ENSG00000187735"	"TCEA1"	"A6NF25; A8K339; hsa:6917; P23193; Q15563; Q6FG87"	""	"Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	"15"	"0"	"315.6"	"580.1"	"672.4"	"305.6"	"677.5"	"368.7"	"743.8"	"686.0"	"961.1"	"1491.4"	"2615.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62910"	"60S ribosomal protein L32 OS=Homo sapiens OX=9606 GN=RPL32 PE=1 SV=2"	"33"	"4"	"18"	"4"	"135"	"15.9"	"11.33"	"3496.98"	"27.69"	"4"	"4"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01655"	"6161"	"ENSG00000144713"	"RPL32"	"B2R4Q3; hsa:6161; P02433; P62910"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"314.8"	"613.1"	"509.9"	"274.8"	"479.3"	"269.8"	"944.2"	"839.9"	"975.5"	"1155.5"	"1757.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q02543"	"60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2"	"51"	"10"	"19"	"10"	"176"	"20.7"	"10.71"	"3865.29"	"27.62"	"10"	"7"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01775"	"6142"	"ENSG00000105640"	"RPL18A"	"hsa:6142; Q02543"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"15"	"0"	"958.1"	"1396.8"	"1451.7"	"847.3"	"1459.2"	"1006.1"	"3002.2"	"1978.5"	"2518.0"	"2677.9"	"3569.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y697"	"Cysteine desulfurase, mitochondrial OS=Homo sapiens OX=9606 GN=NFS1 PE=1 SV=3"	"21"	"8"	"15"	"8"	"457"	"50.2"	"8.31"	"3240.85"	"27.55"	"7"	"6"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf00266"	"9054"	"ENSG00000244005"	"NFS1"	"B3KMA5; B4DXK9; E1P5R8; F5GYK5; hsa:9054; Q6P0L8; Q9NTZ5; Q9Y481; Q9Y697"	"Iron-sulfur cluster biogenesis"	""	"1"	"0"	"170.9"	"399.6"	"413.0"	"187.7"	"408.3"	"216.3"	"458.1"	"617.9"	"1103.6"	"1587.9"	"2898.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P80723"	"Brain acid soluble protein 1 OS=Homo sapiens OX=9606 GN=BASP1 PE=1 SV=2"	"37"	"6"	"12"	"6"	"227"	"22.7"	"4.63"	"2254.38"	"27.54"	"5"	"4"	"RNA metabolism OR transcription;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05466"	"10409"	"ENSG00000176788"	"BASP1"	"B4DJA8; D3DTD5; hsa:10409; O43596; P80723; Q5U0S0; Q9BWA5"	""	"RHOF GTPase cycle"	"1"	"0"	"261.9"	"345.9"	"323.3"	"215.2"	"305.8"	"210.8"	"478.3"	"537.5"	"555.8"	"588.1"	"749.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WXF1"	"Paraspeckle component 1 OS=Homo sapiens OX=9606 GN=PSPC1 PE=1 SV=1"	"13"	"6"	"14"	"6"	"523"	"58.7"	"6.67"	"2030.70"	"27.48"	"5"	"6"	"stress response;other biological processes"	"nucleus;other cell component"	""	"Pf00076, Pf08075"	"55269"	"ENSG00000121390"	"PSPC1"	"hsa:55269; Q5JTQ3; Q8NCZ9; Q8WXE8; Q8WXF1; Q9NV36"	""	""	"0"	"0"	"355.2"	"736.4"	"724.9"	"344.0"	"673.9"	"382.5"	"984.3"	"824.0"	"1393.1"	"2078.6"	"2457.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H078"	"Caseinolytic peptidase B protein homolog OS=Homo sapiens OX=9606 GN=CLPB PE=1 SV=1"	"13"	"7"	"13"	"7"	"707"	"78.7"	"9.01"	"2118.90"	"27.35"	"6"	"7"	"stress response;signal transduction;other biological processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf07724, Pf10431, Pf12796, Pf13857"	"81570"	"ENSG00000162129"	"CLPB"	"B4DXJ7; B4DXP7; B4DXW4; E7EWN6; F8W7P6; hsa:81570; Q8ND11; Q9H078; Q9H8Y0"	""	""	"0"	"0"	"141.4"	"271.8"	"280.5"	"130.8"	"311.4"	"167.7"	"604.6"	"448.0"	"955.0"	"1641.4"	"2747.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P24534"	"Elongation factor 1-beta OS=Homo sapiens OX=9606 GN=EEF1B2 PE=1 SV=3"	"40"	"10"	"20"	"8"	"225"	"24.7"	"4.67"	"3883.67"	"27.02"	"10"	"8"	"protein metabolism;other metabolic processes"	"cytosol;other cell component"	"enzyme regulator activity;nucleic acid binding activity"	"Pf00736, Pf10587"	"1933"	"ENSG00000114942; ENSG00000283391"	"EEF1B2"	"A8K795; hsa:1933; P24534; Q6IBH9"	"Translation factors"	"Eukaryotic Translation Elongation"	"2"	"0"	"687.4"	"864.1"	"952.2"	"489.4"	"925.4"	"637.1"	"1507.8"	"1283.7"	"1809.1"	"1993.2"	"2537.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52209"	"6-phosphogluconate dehydrogenase, decarboxylating OS=Homo sapiens OX=9606 GN=PGD PE=1 SV=3"	"17"	"7"	"16"	"7"	"483"	"53.1"	"7.23"	"2479.12"	"27.00"	"6"	"7"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf00393, Pf03446"	"5226"	"ENSG00000142657"	"PGD"	"A8K2Y9; B4DQJ8; hsa:5226; P52209; Q9BWD8"	"Pentose phosphate metabolism; Nuclear receptors meta-pathway; NRF2 pathway; VEGFA-VEGFR2 signaling; Metabolic reprogramming in colon cancer"	"NFE2L2 regulates pentose phosphate pathway genes; Pentose phosphate pathway"	"7"	"0"	"703.2"	"1547.8"	"1480.2"	"603.8"	"1454.8"	"787.4"	"844.5"	"568.5"	"857.4"	"1272.2"	"2703.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07195"	"L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2"	"27"	"8"	"16"	"7"	"334"	"36.6"	"6.05"	"2803.26"	"26.92"	"8"	"8"	"other metabolic processes"	"other membranes;cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00056, Pf02866"	"3945"	"ENSG00000111716"	"LDHB"	"hsa:3945; P07195"	"Clear cell renal cell carcinoma pathways; CCL18 signaling pathway; Glycolysis and gluconeogenesis"	"Pyruvate metabolism"	"4"	"1"	"277.2"	"2643.5"	"2165.8"	"169.0"	"1905.2"	"446.5"	"674.0"	"408.4"	"584.7"	"702.4"	"1877.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05023"	"Sodium/potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1"	"9"	"7"	"14"	"7"	"1023"	"112.8"	"5.49"	"2600.81"	"26.77"	"7"	"7"	"transport;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;other cell component"	"transporter activity;other molecular function"	"Pf00122, Pf00689, Pf00690, Pf13246"	"476"	"ENSG00000163399"	"ATP1A1"	"B2RBR6; B7Z2T5; B7Z3U6; F5H3A1; hsa:476; P05023; Q16689; Q6LDM4; Q9UCN1; Q9UJ20; Q9UJ21"	"Pre-implantation embryo; Proximal tubule transport; Arsenic metabolism and reactive oxygen species generation"	"Potential therapeutics for SARS; Ion homeostasis; Ion transport by P-type ATPases"	"6"	"0"	"276.0"	"946.1"	"827.6"	"218.7"	"764.7"	"304.7"	"596.7"	"426.1"	"646.3"	"882.9"	"1450.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13435"	"Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2"	"12"	"9"	"19"	"9"	"895"	"100.2"	"5.67"	"3313.11"	"26.68"	"8"	"8"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf02037, Pf04037, Pf04046"	"10992"	"ENSG00000087365"	"SF3B2"	"A8K485; B4DT19; hsa:10992; Q13435; Q7L4T5; Q7Z627; Q969K1; Q96CM6; Q9BWD2"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"3"	"0"	"429.6"	"1017.7"	"1136.1"	"383.2"	"990.2"	"463.3"	"1260.7"	"917.6"	"1449.5"	"1822.4"	"2564.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P38919"	"Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4"	"20"	"7"	"15"	"6"	"411"	"46.8"	"6.73"	"3492.65"	"26.67"	"7"	"6"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"9775"	"ENSG00000141543"	"EIF4A3"	"hsa:9775; P38919; Q15033; Q6IBQ2; Q96A18"	""	"mRNA Splicing - Major Pathway; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Deadenylation of mRNA; ISG15 antiviral mechanism; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"8"	"0"	"270.7"	"996.9"	"813.2"	"252.2"	"783.0"	"344.9"	"621.3"	"506.7"	"686.9"	"801.1"	"1412.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y285"	"Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3"	"9"	"6"	"16"	"6"	"508"	"57.5"	"7.80"	"2897.24"	"26.60"	"5"	"6"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01409, Pf18552, Pf18553, Pf18554"	"2193"	"ENSG00000179115"	"FARSA"	"B4E363; hsa:2193; Q9NSD8; Q9Y285; Q9Y4W8"	""	"Cytosolic tRNA aminoacylation"	"1"	"0"	"417.2"	"796.8"	"780.5"	"418.6"	"758.2"	"436.0"	"882.8"	"771.9"	"1029.5"	"1324.6"	"1948.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86UE4"	"Protein LYRIC OS=Homo sapiens OX=9606 GN=MTDH PE=1 SV=2"	"16"	"8"	"18"	"8"	"582"	"63.8"	"9.32"	"4325.31"	"26.59"	"8"	"6"	"RNA metabolism OR transcription;signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf15686"	"92140"	"ENSG00000147649"	"MTDH"	"hsa:92140; Q05DH2; Q52QU9; Q6PK07; Q86UE4; Q8TCX3"	"Gastric cancer network 2; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; CCL18 signaling pathway"	""	"3"	"0"	"599.6"	"1110.6"	"1199.8"	"514.8"	"1171.0"	"644.6"	"1395.0"	"1111.9"	"1787.8"	"2483.1"	"4319.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P41252"	"Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2"	"8"	"9"	"15"	"9"	"1262"	"144.4"	"6.15"	"2115.75"	"26.31"	"6"	"9"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00133, Pf08264, Pf19302"	"3376"	"ENSG00000196305"	"IARS1"	"A8KAE9; hsa:3376; P41252; Q5TCD0; Q7Z3T4; Q9H588"	"Amino acid metabolism"	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"3"	"0"	"284.1"	"1152.3"	"1082.2"	"256.0"	"830.6"	"319.1"	"589.6"	"485.3"	"701.9"	"1017.6"	"1783.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86XP3"	"ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1"	"12"	"9"	"16"	"9"	"938"	"102.9"	"7.02"	"3146.40"	"26.27"	"8"	"8"	"other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"11325"	"ENSG00000198231"	"DDX42"	"A6NML1; A8KA43; hsa:11325; O75619; Q68G51; Q86XP3; Q96BK1; Q96HR7; Q9Y3V8"	""	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"2"	"0"	"391.0"	"636.5"	"636.3"	"350.3"	"606.7"	"403.7"	"649.1"	"553.0"	"728.9"	"840.5"	"1035.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NVA2"	"Septin-11 OS=Homo sapiens OX=9606 GN=SEPTIN11 PE=1 SV=3"	"17"	"6"	"16"	"5"	"429"	"49.4"	"6.81"	"2737.81"	"26.20"	"6"	"6"	"cell cycle OR cell proliferation"	"cytoskeleton;other cell component"	"other molecular function"	"Pf00735"	"55752"	"ENSG00000138758"	"SEPTIN11"	"B7Z7Z6; E9KL32; hsa:55752; Q4W5G1; Q7L4N1; Q96SP1; Q9NVA2; Q9UFY9"	"22q11.2 copy number variation syndrome"	""	"1"	"0"	"195.2"	"322.9"	"417.5"	"183.0"	"354.0"	"229.0"	"654.1"	"458.7"	"777.7"	"938.3"	"1589.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P18077"	"60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A PE=1 SV=2"	"54"	"10"	"21"	"10"	"110"	"12.5"	"11.06"	"3270.46"	"26.19"	"8"	"7"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01247"	"6165"	"ENSG00000182899"	"RPL35A"	"hsa:6165; P18077; Q08ES9; Q9BVN7"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"890.4"	"2187.7"	"2110.4"	"711.6"	"2029.0"	"854.6"	"3981.0"	"3129.1"	"3711.0"	"5429.7"	"8701.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75533"	"Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3"	"7"	"8"	"15"	"8"	"1304"	"145.7"	"7.09"	"2608.24"	"25.90"	"6"	"7"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf08920"	"23451"	"ENSG00000115524"	"SF3B1"	"E9PCH3; hsa:23451; O75533"	"mRNA processing"	"mRNA Splicing - Major Pathway; B-WICH complex positively regulates rRNA expression; mRNA Splicing - Minor Pathway"	"4"	"0"	"201.5"	"408.0"	"419.9"	"191.7"	"398.5"	"233.2"	"446.5"	"346.0"	"544.3"	"675.3"	"901.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25786"	"Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1"	"22"	"5"	"13"	"5"	"263"	"29.5"	"6.61"	"2434.99"	"25.84"	"5"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00227, Pf10584"	"5682"	"ENSG00000129084"	"PSMA1"	"A8K400; hsa:5682; P25786; Q53YE8; Q9BRV9"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; UCH proteinases; Ubiquitin-dependent degradation of Cyclin D; SCF(Skp2)-mediated degradation of p27/p21; Regulation of expression of SLITs and ROBOs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"62"	"0"	"304.9"	"422.5"	"586.1"	"258.0"	"534.3"	"340.8"	"642.1"	"451.9"	"678.1"	"764.5"	"1239.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95747"	"Serine/threonine-protein kinase OSR1 OS=Homo sapiens OX=9606 GN=OXSR1 PE=1 SV=1"	"15"	"6"	"11"	"6"	"527"	"58.0"	"6.43"	"1233.87"	"25.80"	"2"	"5"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf12202"	"9943"	"ENSG00000172939"	"OXSR1"	"hsa:9943; O95747; Q3LR53; Q7Z501; Q9UPQ1"	""	""	"0"	"0"	"69.7"	"172.3"	"171.9"	"59.9"	"164.7"	"96.5"	"169.3"	"131.2"	"222.4"	"693.6"	"2417.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62333"	"26S proteasome regulatory subunit 10B OS=Homo sapiens OX=9606 GN=PSMC6 PE=1 SV=1"	"20"	"8"	"14"	"8"	"389"	"44.1"	"7.49"	"2236.45"	"25.79"	"6"	"8"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf16450, Pf17862"	"5706"	"ENSG00000100519"	"PSMC6"	"B2R975; hsa:5706; P49719; P62333; Q6IBU3; Q92524"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Ciliary landscape; Alzheimer's disease"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; SARS-CoV-1 targets host intracellular signalling and regulatory pathways"	"65"	"0"	"334.8"	"764.6"	"795.3"	"318.6"	"709.3"	"389.9"	"591.8"	"450.4"	"721.7"	"870.0"	"1287.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P24752"	"Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1"	"23"	"9"	"16"	"9"	"427"	"45.2"	"8.85"	"2292.57"	"25.78"	"6"	"8"	"other metabolic processes;stress response;developmental processes;other biological processes"	"mitochondrion;ER/Golgi"	"other molecular function"	"Pf00108, Pf02803"	"38"	"ENSG00000075239"	"ACAT1"	"B2R6H1; G3XAB4; hsa:38; P24752; Q96FG8"	"Fatty acid beta-oxidation; Tryptophan metabolism; SARS-CoV-2 and COVID-19 pathway"	"Branched-chain amino acid catabolism; Utilization of Ketone Bodies; Synthesis of Ketone Bodies"	"6"	"0"	"673.3"	"1316.3"	"1333.7"	"565.1"	"1306.7"	"733.7"	"1154.1"	"888.3"	"1246.1"	"1730.8"	"3641.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99460"	"26S proteasome non-ATPase regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PSMD1 PE=1 SV=2"	"9"	"7"	"15"	"7"	"953"	"105.8"	"5.39"	"2656.51"	"25.73"	"6"	"7"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf01851, Pf13646, Pf18004"	"5707"	"ENSG00000173692"	"PSMD1"	"B8ZZH9; hsa:5707; Q24JU0; Q53TI2; Q6GMU5; Q6P2P4; Q6PJM7; Q6PKG9; Q86VU1; Q8IV79; Q99460"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"Neutrophil degranulation; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; MAPK6/MAPK4 signaling; The role of GTSE1 in G2/M progression after G2 checkpoint; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"64"	"0"	"592.0"	"1101.8"	"1164.0"	"448.2"	"1071.7"	"629.2"	"740.3"	"578.9"	"792.9"	"980.3"	"1641.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BZ29"	"Dedicator of cytokinesis protein 9 OS=Homo sapiens OX=9606 GN=DOCK9 PE=1 SV=2"	"4"	"8"	"15"	"6"	"2069"	"236.3"	"7.49"	"2447.31"	"25.72"	"6"	"7"	"signal transduction;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity"	"Pf00169, Pf06920, Pf11878, Pf14429, Pf20421, Pf20422"	"23348"	"ENSG00000088387"	"DOCK9"	"B3KX25; E9PFM9; hsa:23348; Q5JUD4; Q5JUD6; Q5T2Q1; Q5TAN8; Q9BZ25; Q9BZ26; Q9BZ27; Q9BZ28; Q9BZ29; Q9UPU4"	""	"CDC42 GTPase cycle; RAC1 GTPase cycle; Factors involved in megakaryocyte development and platelet production"	"3"	"0"	"89.2"	"182.5"	"179.5"	"84.8"	"204.2"	"124.4"	"258.3"	"252.7"	"545.5"	"829.7"	"1116.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UNX3"	"60S ribosomal protein L26-like 1 OS=Homo sapiens OX=9606 GN=RPL26L1 PE=1 SV=1"	"34"	"9"	"26"	"1"	"145"	"17.2"	"10.55"	"5387.06"	"25.61"	"9"	"6"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00467, Pf16906"	"51121"	"ENSG00000037241"	"RPL26L1"	"B3KY82; D3DQM0; hsa:51121; Q9UNX3"	""	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"13"	"0"	"11.3"	"16.7"	"19.3"	"6.5"	"16.8"	"9.9"	"44.2"	"34.2"	"34.4"	"49.2"	"63.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14866"	"Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2"	"17"	"6"	"13"	"5"	"589"	"64.1"	"8.22"	"2155.09"	"25.41"	"5"	"6"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf11835, Pf13893"	"3191"	"ENSG00000104824; ENSG00000282947"	"HNRNPL"	"A6ND69; A6NIT8; hsa:3191; P14866; Q9H3P3"	"mRNA processing; Hippocampal synaptogenesis and neurogenesis; 11p11.2 copy number variation syndrome"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"5"	"1"	"764.1"	"903.0"	"856.4"	"621.0"	"951.4"	"751.1"	"937.1"	"603.4"	"816.9"	"796.4"	"1150.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14011"	"Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1"	"39"	"5"	"9"	"5"	"172"	"18.6"	"9.51"	"741.81"	"25.18"	"2"	"5"	"cell organization and biogenesis;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"1153"	"ENSG00000099622"	"CIRBP"	"B3KT17; B4E2X2; hsa:1153; Q14011"	""	""	"0"	"0"	"175.6"	"245.6"	"253.7"	"165.2"	"270.0"	"196.5"	"415.1"	"397.1"	"475.1"	"557.6"	"604.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99729"	"Heterogeneous nuclear ribonucleoprotein A/B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2"	"26"	"8"	"18"	"6"	"332"	"36.2"	"8.21"	"2423.37"	"25.15"	"6"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08143"	"3182"	"ENSG00000197451"	"HNRNPAB"	"B3KNN5; D3DWP7; hsa:3182; Q04150; Q8N7U3; Q99729; Q9BQ99"	"Pre-implantation embryo; mRNA processing"	""	"2"	"0"	"431.6"	"1000.3"	"960.6"	"341.9"	"838.1"	"404.2"	"858.8"	"645.6"	"856.8"	"917.5"	"1357.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63220"	"40S ribosomal protein S21 OS=Homo sapiens OX=9606 GN=RPS21 PE=1 SV=1"	"48"	"4"	"16"	"4"	"83"	"9.1"	"8.50"	"2392.00"	"25.08"	"4"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01249"	"6227"	"ENSG00000171858"	"RPS21"	"hsa:6227; P35265; P63220"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"640.7"	"1029.2"	"1082.2"	"521.8"	"1059.8"	"597.6"	"1788.2"	"1363.8"	"1848.7"	"2108.2"	"2883.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P78347"	"General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2"	"11"	"9"	"17"	"9"	"998"	"112.3"	"6.39"	"3101.49"	"25.02"	"7"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02946"	"2969"	"ENSG00000263001"	"GTF2I"	"hsa:2969; O14743; O15359; O43546; O43588; O43589; P78347; Q75M85; Q75M86; Q75M87; Q75M88; Q86U51; Q9BSZ4"	"B cell receptor signaling pathway; 7q11.23 copy number variation syndrome; Genetic causes of porto-sinusoidal vascular disease"	""	"3"	"0"	"364.4"	"840.8"	"812.6"	"316.1"	"758.5"	"359.3"	"921.4"	"657.3"	"1023.3"	"1679.9"	"2538.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IZP0"	"Abl interactor 1 OS=Homo sapiens OX=9606 GN=ABI1 PE=1 SV=4"	"16"	"6"	"14"	"4"	"508"	"55.0"	"7.06"	"3166.09"	"25.01"	"5"	"5"	"cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00018, Pf07815"	"10006"	"ENSG00000136754"	"ABI1"	"A9Z1Y6; B3KX62; B4DQ58; H7BXI6; hsa:10006; O15147; O76049; O95060; Q5T2R3; Q5T2R4; Q5T2R6; Q5T2R7; Q5T2R9; Q5W070; Q5W072; Q8IZP0; Q8TB63; Q96S81; Q9NXZ9; Q9NYB8"	"EGF/EGFR signaling pathway"	"RAC2 GTPase cycle; RAC1 GTPase cycle; RAC3 GTPase cycle; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; VEGFA-VEGFR2 Pathway"	"8"	"2"	"460.1"	"584.7"	"718.0"	"387.2"	"653.0"	"499.9"	"975.6"	"766.3"	"1117.9"	"1426.4"	"1928.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62857"	"40S ribosomal protein S28 OS=Homo sapiens OX=9606 GN=RPS28 PE=1 SV=1"	"68"	"6"	"16"	"6"	"69"	"7.8"	"10.70"	"2995.84"	"24.89"	"6"	"6"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01200"	"6234"	"ENSG00000233927"	"RPS28"	"hsa:6234; P25112; P62857"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; SARS-CoV-2 modulates host translation machinery"	"19"	"0"	"275.2"	"636.8"	"674.0"	"243.0"	"765.5"	"291.7"	"971.8"	"756.4"	"972.2"	"1514.7"	"2090.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25098"	"Beta-adrenergic receptor kinase 1 OS=Homo sapiens OX=9606 GN=GRK2 PE=1 SV=2"	"16"	"9"	"14"	"9"	"689"	"79.5"	"7.28"	"2120.19"	"24.81"	"7"	"7"	"cell-cell signaling;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"signal transduction activity or receptor binding;kinase activity;other molecular function"	"Pf00069, Pf00169, Pf00615"	"156"	"ENSG00000173020"	"GRK2"	"B0ZBE1; hsa:156; P25098; Q13837; Q6GTT3"	"Chemokine signaling pathway; Hedgehog signaling pathway; Hedgehog signaling pathway"	"G alpha (q) signalling events; Activation of SMO; G alpha (s) signalling events; Cargo recognition for clathrin-mediated endocytosis; Calmodulin induced events"	"8"	"0"	"106.9"	"247.1"	"284.9"	"116.3"	"290.5"	"142.0"	"343.2"	"357.0"	"908.2"	"2054.5"	"2747.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35579"	"Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4"	"5"	"7"	"14"	"4"	"1960"	"226.4"	"5.60"	"2009.31"	"24.79"	"5"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00063, Pf01576, Pf02736"	"4627"	"ENSG00000100345"	"MYH9"	"A8K6E4; hsa:4627; O60805; P35579; Q60FE2; Q86T83"	"Primary focal segmental glomerulosclerosis (FSGS); VEGFA-VEGFR2 signaling; Nephrotic syndrome"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Signaling by ALK fusions and activated point mutants; RHO GTPases activate CIT; EPHA-mediated growth cone collapse; Sema4D induced cell migration and growth-cone collapse; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; RHO GTPases activate PAKs; CD163 mediating an anti-inflammatory response"	"16"	"2"	"19.2"	"54.1"	"78.4"	"19.6"	"62.3"	"32.2"	"85.5"	"64.5"	"100.7"	"120.4"	"158.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09622"	"Dihydrolipoyl dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=DLD PE=1 SV=2"	"11"	"7"	"18"	"7"	"509"	"54.1"	"7.85"	"2607.03"	"24.79"	"5"	"7"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytoskeleton;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf02852, Pf07992"	"1738"	"ENSG00000091140"	"DLD"	"B2R5X0; B4DHG0; B4DT69; hsa:1738; P09622; Q14131; Q14167; Q59EV8; Q8WTS4"	"Fatty acid beta-oxidation; TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Tryptophan metabolism; 7q11.23 copy number variation syndrome; Neuroinflammation and glutamatergic signaling; Glycolysis and gluconeogenesis; 10q11.21q11.23 copy number variation syndrome; TCA cycle (aka Krebs or citric acid cycle)"	"Lysine catabolism; Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid; Citric acid cycle (TCA cycle); Branched-chain amino acid catabolism; Glycine degradation"	"17"	"0"	"594.5"	"1465.8"	"1583.4"	"572.7"	"1489.4"	"903.0"	"2166.1"	"1798.6"	"2193.0"	"2728.0"	"4189.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92804"	"TATA-binding protein-associated factor 2N OS=Homo sapiens OX=9606 GN=TAF15 PE=1 SV=1"	"14"	"6"	"14"	"3"	"592"	"61.8"	"8.02"	"1800.10"	"24.74"	"4"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00641"	"8148"	"ENSG00000270647; ENSG00000276833"	"TAF15"	"B2R837; hsa:8148; Q86X94; Q92751; Q92804"	"17q12 copy number variation syndrome"	"Regulation of TP53 Activity through Phosphorylation; RNA Polymerase II Pre-transcription Events; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation"	"10"	"0"	"85.2"	"132.7"	"145.7"	"58.7"	"146.5"	"77.7"	"174.7"	"130.4"	"209.0"	"205.8"	"302.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13442"	"28 kDa heat- and acid-stable phosphoprotein OS=Homo sapiens OX=9606 GN=PDAP1 PE=1 SV=1"	"37"	"6"	"15"	"6"	"181"	"20.6"	"8.87"	"3389.25"	"24.70"	"6"	"5"	"signal transduction"	"non-structural extracellular;plasma membrane;other membranes;cytosol;other cell component"	""	"Pf10252"	"11333"	"ENSG00000106244"	"PDAP1"	"D6W5S5; hsa:11333; Q13442; Q92906"	""	"Neutrophil degranulation"	"1"	"0"	"563.0"	"666.1"	"763.0"	"474.7"	"803.2"	"617.9"	"1287.3"	"929.4"	"1373.5"	"1368.3"	"1666.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62826"	"GTP-binding nuclear protein Ran OS=Homo sapiens OX=9606 GN=RAN PE=1 SV=3"	"22"	"4"	"11"	"4"	"216"	"24.4"	"7.49"	"1351.28"	"24.69"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00071"	"5901"	"ENSG00000132341"	"RAN"	"A8K3Z8; hsa:5901; P17080; P28746; P28747; P62826; Q6IPB2; Q86V08; Q8NI90; Q9CSP3; Q9CWI7; Q9CZA2; Q9UDJ5; Q9UEU9"	"Androgen receptor signaling pathway; miRNA biogenesis; 22q11.2 copy number variation syndrome"	"Transcriptional regulation by small RNAs; Rev-mediated nuclear export of HIV RNA; NEP/NS2 Interacts with the Cellular Export Machinery; Nuclear import of Rev protein; tRNA processing in the nucleus; Regulation of cholesterol biosynthesis by SREBP (SREBF); MicroRNA (miRNA) biogenesis; Postmitotic nuclear pore complex (NPC) reformation"	"11"	"0"	"363.0"	"1672.2"	"1304.5"	"284.4"	"1165.5"	"384.7"	"434.9"	"314.1"	"496.7"	"610.8"	"1093.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P47897"	"Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1"	"10"	"6"	"16"	"6"	"775"	"87.7"	"7.15"	"2508.95"	"24.60"	"6"	"6"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;mitochondrion;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00749, Pf03950, Pf04557, Pf04558"	"5859"	"ENSG00000172053"	"QARS1"	"B4DWJ2; hsa:5859; P47897"	""	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation; Mitochondrial tRNA aminoacylation"	"3"	"0"	"218.3"	"555.1"	"518.5"	"201.3"	"494.6"	"258.6"	"391.9"	"318.2"	"436.2"	"559.4"	"878.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14776"	"Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2"	"7"	"7"	"15"	"7"	"1098"	"123.8"	"8.65"	"2446.29"	"24.47"	"6"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00397, Pf01846"	"10915"	"ENSG00000113649"	"TCERG1"	"hsa:10915; O14776; Q2NKN2; Q59EA1"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"466.6"	"999.1"	"1027.8"	"461.3"	"973.5"	"515.6"	"1548.9"	"1080.2"	"1567.4"	"2275.8"	"3082.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y230"	"RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3"	"16"	"7"	"14"	"7"	"463"	"51.1"	"5.64"	"1989.38"	"24.25"	"6"	"7"	"cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06068, Pf17856"	"10856"	"ENSG00000183207"	"RUVBL2"	"B3KQ59; E7ETE5; hsa:10856; Q6FIB9; Q6PK27; Q9Y230; Q9Y361"	""	"Telomere Extension By Telomerase; HATs acetylate histones"	"2"	"0"	"183.2"	"696.7"	"592.7"	"160.7"	"499.7"	"200.5"	"322.2"	"267.8"	"373.5"	"526.7"	"908.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q58FF6"	"Putative heat shock protein HSP 90-beta 4 OS=Homo sapiens OX=9606 GN=HSP90AB4P PE=5 SV=1"	"14"	"7"	"15"	"2"	"505"	"58.2"	"4.73"	"2199.58"	"24.13"	"5"	"6"	"stress response;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00183, Pf02518"	""	""	"HSP90AB4P"	"Q58FF6"	""	""	"0"	"0"	"38.3"	"82.0"	"77.5"	"40.7"	"84.9"	"45.3"	"83.6"	"54.9"	"89.6"	"90.8"	"166.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96DI7"	"U5 small nuclear ribonucleoprotein 40 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP40 PE=1 SV=1"	"20"	"4"	"8"	"4"	"357"	"39.3"	"8.10"	"1580.42"	"24.12"	"2"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf00400"	"9410"	"ENSG00000060688"	"SNRNP40"	"B4DQJ1; hsa:9410; O75938; O95320; Q96DI7"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"3"	"0"	"52.0"	"124.9"	"124.5"	"54.6"	"124.7"	"60.3"	"134.8"	"126.8"	"256.2"	"510.4"	"1030.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P54136"	"Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2"	"11"	"6"	"14"	"6"	"660"	"75.3"	"6.68"	"2627.38"	"24.07"	"6"	"6"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00750, Pf03485, Pf05746"	"5917"	"ENSG00000113643"	"RARS1"	"B2RBS9; hsa:5917; P54136; Q53GY4; Q9BWA1"	"Amino acid metabolism"	"Cytosolic tRNA aminoacylation; Selenoamino acid metabolism"	"3"	"0"	"103.4"	"334.7"	"339.8"	"90.1"	"277.6"	"137.2"	"258.4"	"215.4"	"361.5"	"566.2"	"1153.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61353"	"60S ribosomal protein L27 OS=Homo sapiens OX=9606 GN=RPL27 PE=1 SV=2"	"52"	"9"	"20"	"9"	"136"	"15.8"	"10.56"	"2937.38"	"24.07"	"7"	"7"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00467, Pf01777"	"6155"	"ENSG00000131469"	"RPL27"	"hsa:6155; P08526; P61353; Q4G0A9"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"15"	"0"	"934.2"	"1940.4"	"1841.2"	"822.9"	"1876.6"	"984.8"	"3292.8"	"2616.2"	"3401.5"	"4025.8"	"5454.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q4VCS5"	"Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1"	"7"	"8"	"13"	"6"	"1084"	"118.0"	"7.64"	"1521.77"	"24.06"	"5"	"8"	"cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf12240"	"154796"	"ENSG00000126016"	"AMOT"	"hsa:154796; Q4VCS5; Q504X5; Q9HD27; Q9UPT1"	"VEGFA-VEGFR2 signaling; Hippo-Merlin signaling dysregulation; Pleural mesothelioma"	""	"3"	"1"	"418.0"	"658.7"	"660.6"	"357.0"	"661.1"	"409.4"	"726.3"	"587.2"	"804.1"	"978.3"	"1288.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07737"	"Profilin-1 OS=Homo sapiens OX=9606 GN=PFN1 PE=1 SV=2"	"55"	"6"	"13"	"6"	"140"	"15.0"	"8.27"	"2222.11"	"23.98"	"6"	"6"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00235"	"5216"	"ENSG00000108518"	"PFN1"	"hsa:5216; P07737; Q53Y44"	"Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; Burn wound healing; Regulation of actin cytoskeleton; G13 signaling pathway"	"RHO GTPases Activate Formins; Platelet degranulation ; PCP/CE pathway; Signaling by ROBO receptors"	"9"	"0"	"181.8"	"2086.0"	"1371.9"	"89.6"	"860.1"	"239.4"	"377.8"	"281.2"	"431.9"	"577.4"	"1742.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14978"	"Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2"	"9"	"9"	"19"	"9"	"699"	"73.6"	"9.47"	"2678.06"	"23.94"	"7"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05022"	"9221"	"ENSG00000166197"	"NOLC1"	"hsa:9221; Q14978; Q15030; Q5VV70; Q9BUV3"	""	""	"0"	"0"	"691.3"	"842.5"	"1095.9"	"554.5"	"1215.9"	"954.8"	"6400.2"	"3354.9"	"3330.3"	"3569.3"	"5105.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13011"	"Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial OS=Homo sapiens OX=9606 GN=ECH1 PE=1 SV=2"	"23"	"8"	"16"	"8"	"328"	"35.8"	"8.00"	"3230.32"	"23.92"	"7"	"6"	"other metabolic processes"	"cytosol;mitochondrion;other cytoplasmic organelle"	"other molecular function"	"Pf00378"	"1891"	"ENSG00000104823; ENSG00000282853"	"ECH1"	"A8K745; hsa:1891; Q13011; Q8WVX0; Q96EZ9"	"Fatty acid biosynthesis; IL-18 signaling pathway"	"Peroxisomal protein import"	"3"	"0"	"537.7"	"864.7"	"1046.2"	"450.0"	"947.2"	"602.1"	"1518.3"	"1054.8"	"1897.5"	"3055.4"	"5525.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04843"	"Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1"	"11"	"6"	"13"	"6"	"607"	"68.5"	"6.38"	"2331.10"	"23.90"	"5"	"6"	"protein metabolism;other metabolic processes"	"other membranes;cytosol;ER/Golgi;other cell component"	""	"Pf04597"	"6184"	"ENSG00000163902"	"RPN1"	"B2R5Z0; D3DNB6; hsa:6184; P04843; Q68DT1"	"Proteasome degradation; N-glycan biosynthesis"	"SRP-dependent cotranslational protein targeting to membrane; Asparagine N-linked glycosylation; Maturation of spike protein"	"5"	"0"	"162.9"	"608.6"	"537.5"	"168.1"	"463.5"	"191.5"	"321.7"	"268.0"	"381.0"	"580.7"	"878.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82979"	"SAP domain-containing ribonucleoprotein OS=Homo sapiens OX=9606 GN=SARNP PE=1 SV=3"	"38"	"7"	"15"	"7"	"210"	"23.7"	"6.42"	"2419.46"	"23.87"	"6"	"7"	"other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02037"	"84324"	"ENSG00000205323"	"SARNP"	"A8K393; hsa:84324; P82979; Q9P066"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"3"	"0"	"537.8"	"873.4"	"951.6"	"524.5"	"1028.3"	"566.8"	"1607.1"	"1221.5"	"1739.1"	"1837.7"	"2606.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96F07"	"Cytoplasmic FMR1-interacting protein 2 OS=Homo sapiens OX=9606 GN=CYFIP2 PE=1 SV=2"	"7"	"8"	"16"	"2"	"1278"	"148.3"	"7.31"	"2380.11"	"23.82"	"6"	"8"	"cell adhesion;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf05994, Pf07159"	"26999"	"ENSG00000055163"	"CYFIP2"	"A6NLT2; D3DQJ3; hsa:26999; Q53EN5; Q96F07; Q9NTK4; Q9ULQ2; Q9UN29"	"Fragile X syndrome; Regulation of actin cytoskeleton"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RAC1 GTPase cycle; RHO GTPases Activate WASPs and WAVEs; VEGFA-VEGFR2 Pathway"	"7"	"0"	"10.3"	"15.2"	"21.1"	"9.4"	"26.4"	"15.4"	"47.2"	"29.5"	"48.6"	"78.2"	"105.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35269"	"General transcription factor IIF subunit 1 OS=Homo sapiens OX=9606 GN=GTF2F1 PE=1 SV=2"	"16"	"7"	"15"	"7"	"517"	"58.2"	"7.49"	"3462.36"	"23.69"	"7"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf05793"	"2962"	"ENSG00000125651"	"GTF2F1"	"B2RCS0; hsa:2962; P35269; Q9BWN0"	""	"Viral Messenger RNA Synthesis; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; mRNA Splicing - Major Pathway; Estrogen-dependent gene expression; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM"	"32"	"0"	"149.4"	"233.1"	"287.8"	"126.7"	"314.4"	"183.2"	"583.0"	"385.6"	"650.8"	"832.4"	"1388.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08670"	"Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4"	"17"	"7"	"15"	"6"	"466"	"53.6"	"5.12"	"2605.61"	"23.67"	"6"	"7"	"cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00038, Pf04732"	"7431"	"ENSG00000026025"	"VIM"	"B0YJC2; D3DRU4; hsa:7431; P08670; Q15867; Q15868; Q15869; Q548L2; Q6LER9; Q8N850; Q96ML2; Q9NTM3"	"Allograft rejection; Spinal cord injury; Primary focal segmental glomerulosclerosis (FSGS); Mammary gland development pathway - Puberty (Stage 2 of 4); Apoptosis-related network due to altered Notch3 in ovarian cancer; Striated muscle contraction pathway; TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition; Ciliary landscape; Burn wound healing; CCL18 signaling pathway; TROP2 regulatory signaling; CKAP4 signaling pathway map; A network map of Macrophage-stimulating protein (MSP) signaling; T-cell receptor signaling pathway"	"Late endosomal microautophagy; Aggrephagy; Interleukin-4 and Interleukin-13 signaling; Striated Muscle Contraction; RHOBTB1 GTPase cycle; Caspase-mediated cleavage of cytoskeletal proteins; Chaperone Mediated Autophagy"	"21"	"0"	"218.9"	"409.6"	"438.6"	"201.2"	"438.1"	"247.0"	"268.0"	"238.9"	"353.7"	"522.6"	"711.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62136"	"Serine/threonine-protein phosphatase PP1-alpha catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CA PE=1 SV=1"	"27"	"7"	"13"	"3"	"330"	"37.5"	"6.33"	"2291.15"	"23.50"	"6"	"7"	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00149, Pf16891"	"5499"	"ENSG00000172531"	"PPP1CA"	"A6NNR3; B2R908; hsa:5499; P08129; P20653; P22802; P62136; Q07161"	"Sphingolipid pathway; Nicotine effect on dopaminergic neurons; Common pathways underlying drug addiction; Focal adhesion; VEGFA-VEGFR2 signaling; Hippo-Merlin signaling dysregulation; Fragile X syndrome; Netrin-UNC5B signaling pathway; Neuroinflammation and glutamatergic signaling"	"Triglyceride catabolism; Circadian Clock; Downregulation of TGF-beta receptor signaling; DARPP-32 events"	"13"	"3"	"377.9"	"707.9"	"789.6"	"345.9"	"682.4"	"434.4"	"896.2"	"667.1"	"842.5"	"1073.5"	"1448.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61160"	"Actin-related protein 2 OS=Homo sapiens OX=9606 GN=ACTR2 PE=1 SV=1"	"21"	"6"	"11"	"6"	"394"	"44.7"	"6.74"	"1564.91"	"23.44"	"3"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00022"	"10097"	"ENSG00000138071"	"ACTR2"	"B2RCP5; D6W5F4; E9PF41; hsa:10097; O15142; P61160; Q96C82"	"Physico-chemical features and toxicity-associated pathways; Embryonic stem cell pluripotency pathways"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Neutrophil degranulation; Clathrin-mediated endocytosis; EPHB-mediated forward signaling"	"8"	"0"	"127.1"	"275.6"	"288.6"	"110.4"	"295.3"	"181.4"	"431.8"	"454.0"	"668.1"	"1107.0"	"2486.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62899"	"60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1"	"45"	"6"	"16"	"6"	"125"	"14.5"	"10.54"	"2306.63"	"23.20"	"5"	"6"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01198"	"6160"	"ENSG00000071082"	"RPL31"	"B7Z4K2; D3DVJ4; hsa:6160; P12947; P62899; Q53SQ5; Q6IRZ0; Q6LBJ6"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis"	"14"	"0"	"525.5"	"1262.7"	"1151.9"	"457.6"	"1191.0"	"921.3"	"1816.4"	"1367.8"	"1770.7"	"2412.8"	"3561.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05387"	"60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1"	"68"	"4"	"11"	"3"	"115"	"11.7"	"4.54"	"2247.12"	"23.19"	"3"	"3"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf00428"	"6181"	"ENSG00000177600"	"RPLP2"	"hsa:6181; P05387; Q6FG96"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins; Opioid receptor pathways"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"16"	"1"	"104.2"	"258.6"	"297.5"	"94.9"	"268.2"	"138.0"	"341.6"	"189.6"	"325.4"	"353.4"	"602.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P42285"	"Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3"	"10"	"8"	"15"	"8"	"1042"	"117.7"	"6.52"	"2075.98"	"23.17"	"7"	"8"	"RNA metabolism OR transcription;other metabolic processes;stress response"	"nucleus"	"other molecular function"	"Pf00270, Pf00271, Pf08148, Pf13234"	"23517"	"ENSG00000039123"	"MTREX"	"hsa:23517; P42285; Q2M386; Q6MZZ8; Q6P170; Q8N5R0; Q8TAG2"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; mRNA Splicing - Major Pathway"	"2"	"0"	"145.8"	"291.4"	"317.7"	"109.4"	"308.0"	"146.3"	"383.1"	"323.5"	"491.2"	"714.6"	"1188.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q07021"	"Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1"	"32"	"6"	"14"	"6"	"282"	"31.3"	"4.84"	"2676.37"	"23.11"	"5"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;translation activity;nucleic acid binding activity;other molecular function"	"Pf02330"	"708"	"ENSG00000108561"	"C1QBP"	"hsa:708; Q07021; Q2HXR8; Q9NNY8"	"Complement system; Mesodermal commitment pathway; Ebola virus infection in host"	"RHOC GTPase cycle; RHOA GTPase cycle; Intrinsic Pathway of Fibrin Clot Formation; Apoptotic factor-mediated response; Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function"	"8"	"0"	"299.7"	"668.9"	"707.8"	"247.4"	"630.7"	"319.8"	"501.4"	"426.5"	"540.7"	"634.8"	"957.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HCC0"	"Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC2 PE=1 SV=1"	"17"	"9"	"18"	"9"	"563"	"61.3"	"7.68"	"3776.70"	"23.09"	"9"	"6"	"other metabolic processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf01039"	"64087"	"ENSG00000131844"	"MCCC2"	"A6NIY9; hsa:64087; Q96C27; Q9HCC0; Q9Y4L7"	""	"Biotin transport and metabolism; Branched-chain amino acid catabolism; Defective HLCS causes multiple carboxylase deficiency"	"3"	"0"	"525.8"	"756.4"	"782.9"	"456.6"	"770.7"	"518.2"	"797.6"	"747.8"	"961.9"	"1094.6"	"1626.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30533"	"Alpha-2-macroglobulin receptor-associated protein OS=Homo sapiens OX=9606 GN=LRPAP1 PE=1 SV=1"	"26"	"8"	"13"	"8"	"357"	"41.4"	"8.78"	"2454.75"	"22.86"	"7"	"6"	"transport;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf06400, Pf06401"	"4043"	"ENSG00000163956"	"LRPAP1"	"D3DVR9; hsa:4043; P30533; Q2M310; Q53HQ3; Q53HS6"	"Cholesterol metabolism"	""	"1"	"0"	"158.1"	"384.8"	"379.6"	"143.6"	"357.1"	"209.0"	"602.0"	"621.7"	"2790.3"	"3649.7"	"4109.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13492"	"Phosphatidylinositol-binding clathrin assembly protein OS=Homo sapiens OX=9606 GN=PICALM PE=1 SV=2"	"10"	"5"	"10"	"5"	"652"	"70.7"	"7.90"	"1801.78"	"22.78"	"4"	"5"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf07651"	"8301"	"ENSG00000073921"	"PICALM"	"B4DTM3; E9PN05; F8VPG7; hsa:8301; O60700; Q13492; Q4LE54; Q6GMQ6; Q86XZ9"	""	"Cargo recognition for clathrin-mediated endocytosis; Golgi Associated Vesicle Biogenesis; RND3 GTPase cycle"	"4"	"0"	"73.6"	"142.6"	"173.0"	"90.4"	"157.3"	"113.5"	"245.3"	"364.4"	"769.2"	"1643.2"	"3071.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H1E3"	"Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 OS=Homo sapiens OX=9606 GN=NUCKS1 PE=1 SV=1"	"18"	"3"	"12"	"3"	"243"	"27.3"	"5.08"	"2571.84"	"22.74"	"3"	"3"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	""	"64710"	"ENSG00000069275"	"NUCKS1"	"hsa:64710; Q54AC0; Q5PXE7; Q9H1D6; Q9H1E3; Q9H723"	""	""	"0"	"0"	"338.6"	"632.5"	"660.6"	"269.7"	"667.4"	"324.2"	"1017.7"	"749.3"	"886.1"	"876.8"	"1216.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P18859"	"ATP synthase-coupling factor 6, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PF PE=1 SV=1"	"39"	"3"	"12"	"3"	"108"	"12.6"	"9.52"	"2447.39"	"22.72"	"3"	"3"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf05511"	"522"	"ENSG00000154723"	"ATP5PF"	"hsa:522; J3KQ83; P18859"	"Electron transport chain: OXPHOS system in mitochondria; Oxidative phosphorylation"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"4"	"0"	"348.2"	"634.9"	"684.4"	"349.7"	"659.7"	"401.2"	"683.6"	"588.6"	"741.8"	"848.1"	"1267.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P26599"	"Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1"	"19"	"7"	"19"	"6"	"531"	"57.2"	"9.17"	"3861.04"	"22.67"	"5"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf11835, Pf13893"	"749887"	"ENSPPYG00000009289; ENSPTRG00000010165"	"PTBP1"	"A0A2J8IKP3; A0A2J8RA51; A0A6D2WFY9; A0A8I5YPF9; K7AXA8"	""	""	"0"	"3"	"544.9"	"1475.8"	"1415.3"	"512.3"	"1216.2"	"641.0"	"1646.0"	"1248.4"	"1924.0"	"2213.0"	"3741.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14678"	"Small nuclear ribonucleoprotein-associated proteins B and B' OS=Homo sapiens OX=9606 GN=SNRPB PE=1 SV=2"	"13"	"4"	"13"	"4"	"240"	"24.6"	"11.19"	"1985.25"	"22.61"	"3"	"4"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01423"	"6628"	"ENSG00000125835"	"SNRPB"	"hsa:6628; P14678; Q15490; Q6IB35; Q9UIS5"	"mRNA processing"	"snRNP Assembly; RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway; SARS-CoV-2 modulates host translation machinery; mRNA Splicing - Minor Pathway; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"8"	"0"	"232.3"	"872.6"	"778.3"	"203.3"	"585.7"	"224.8"	"585.9"	"468.7"	"746.7"	"1085.2"	"1650.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BY77"	"Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2"	"20"	"7"	"13"	"7"	"421"	"46.1"	"9.99"	"2126.56"	"22.50"	"6"	"7"	"other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"84271"	"ENSG00000100227"	"POLDIP3"	"A8K6F8; A8K6V9; hsa:84271; Q009A7; Q5H972; Q6PGN6; Q7Z6Z0; Q9BY77; Q9NSP5; Q9NSP6"	""	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript"	"3"	"0"	"217.7"	"351.7"	"345.6"	"177.1"	"342.5"	"205.9"	"553.9"	"417.7"	"564.5"	"644.4"	"936.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P42704"	"Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3"	"6"	"8"	"13"	"8"	"1394"	"157.8"	"6.13"	"1573.96"	"22.45"	"5"	"8"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"other membranes;cytoskeleton;mitochondrion;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf01535"	"10128"	"ENSG00000138095"	"LRPPRC"	"A0PJE3; A8K1V1; hsa:10128; P42704; Q53PC0; Q53QN7; Q6ZUD8; Q7Z7A6; Q96D84"	"Ciliary landscape"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"4"	"0"	"292.9"	"1330.3"	"1150.0"	"298.4"	"943.8"	"393.9"	"717.7"	"593.6"	"795.2"	"1151.1"	"1898.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43488"	"Aflatoxin B1 aldehyde reductase member 2 OS=Homo sapiens OX=9606 GN=AKR7A2 PE=1 SV=3"	"20"	"7"	"15"	"7"	"359"	"39.6"	"7.17"	"2734.63"	"22.29"	"6"	"6"	"other metabolic processes"	"cytosol;mitochondrion;ER/Golgi;other cell component"	"other molecular function"	"Pf00248"	"8574"	"ENSG00000053371"	"AKR7A2"	"hsa:8574; O43488; O75749; Q5TG63"	"Aflatoxin B1 metabolism; Metapathway biotransformation Phase I and II"	"Aflatoxin activation and detoxification"	"3"	"0"	"643.6"	"1276.2"	"1329.6"	"560.2"	"1333.3"	"759.1"	"1069.3"	"899.9"	"1331.2"	"1635.7"	"2505.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BSD7"	"Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1"	"25"	"5"	"16"	"5"	"190"	"20.7"	"9.54"	"2597.41"	"22.23"	"4"	"5"	""	""	"other molecular function"	"Pf03266"	"84284"	"ENSG00000135778"	"NTPCR"	"hsa:84284; Q9BSD7"	""	""	"0"	"0"	"380.4"	"679.3"	"659.0"	"315.0"	"648.8"	"373.5"	"1050.3"	"796.5"	"1110.7"	"1902.8"	"3343.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75643"	"U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2"	"4"	"7"	"14"	"7"	"2136"	"244.4"	"6.06"	"2455.63"	"22.10"	"7"	"7"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00270, Pf00271, Pf02889, Pf18149"	"23020"	"ENSG00000144028"	"SNRNP200"	"hsa:23020; O75643; O94884; Q6NZY0; Q6PX59; Q8NBE6; Q96IF2; Q9H7S0"	"2q11.2 copy number variation syndrome"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"3"	"0"	"117.7"	"254.2"	"272.4"	"109.7"	"258.3"	"141.4"	"272.8"	"214.3"	"310.9"	"427.2"	"607.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P32929"	"Cystathionine gamma-lyase OS=Homo sapiens OX=9606 GN=CTH PE=1 SV=3"	"21"	"6"	"13"	"6"	"405"	"44.5"	"6.70"	"2008.74"	"22.07"	"5"	"6"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf01053"	"1491"	"ENSG00000116761"	"CTH"	"B4E1R2; E9PDV0; hsa:1491; P32929; Q53FB3; Q53Y79; Q9H4W7; Q9H4W8"	"Selenium micronutrient network; Vitamin B12 metabolism; Folate metabolism; Trans-sulfuration pathway; Trans-sulfuration, one-carbon metabolism and related pathways; Amino acid metabolism; Methionine metabolism leading to sulfur amino acids and related disorders; Ferroptosis"	"Degradation of cysteine and homocysteine; Metabolism of ingested SeMet, Sec, MeSec into H2Se; Cysteine formation from homocysteine"	"11"	"0"	"107.9"	"250.5"	"230.4"	"92.5"	"210.6"	"103.9"	"172.1"	"148.8"	"200.3"	"238.8"	"378.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63279"	"SUMO-conjugating enzyme UBC9 OS=Homo sapiens OX=9606 GN=UBE2I PE=1 SV=1"	"34"	"4"	"8"	"4"	"158"	"18.0"	"8.66"	"686.90"	"22.07"	"2"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00179"	"7329"	"ENSG00000103275"	"UBE2I"	"D3DU69; hsa:7329; P50550; P63279; Q15698; Q59GX1; Q86VB3"	"Androgen receptor signaling pathway"	"SUMOylation of RNA binding proteins; Formation of Incision Complex in GG-NER; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; Meiotic synapsis; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of DNA replication proteins; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; SUMOylation of intracellular receptors; Processing of DNA double-strand break ends; Vitamin D (calciferol) metabolism; SUMOylation of transcription factors; Postmitotic nuclear pore complex (NPC) reformation; Negative regulation of activity of TFAP2 (AP-2) family transcription factors; Maturation of nucleoprotein; SUMOylation of immune response proteins; SUMOylation of nuclear envelope proteins; Maturation of nucleoprotein; SUMO is transferred from E1 to E2 (UBE2I, UBC9)"	"24"	"0"	"119.0"	"229.4"	"262.6"	"101.4"	"260.1"	"136.1"	"244.9"	"214.8"	"394.8"	"810.9"	"2380.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q07955"	"Serine/arginine-rich splicing factor 1 OS=Homo sapiens OX=9606 GN=SRSF1 PE=1 SV=2"	"36"	"7"	"11"	"7"	"248"	"27.7"	"10.36"	"1588.32"	"21.98"	"5"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6426"	"ENSG00000136450"	"SRSF1"	"B2R6Z7; D3DTZ3; hsa:6426; Q07955; Q13809"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"7"	"0"	"249.2"	"686.0"	"675.6"	"247.5"	"693.2"	"287.0"	"690.3"	"544.7"	"711.0"	"984.1"	"1473.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60216"	"Double-strand-break repair protein rad21 homolog OS=Homo sapiens OX=9606 GN=RAD21 PE=1 SV=2"	"11"	"6"	"11"	"6"	"631"	"71.6"	"4.65"	"1740.18"	"21.95"	"4"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04824, Pf04825"	"5885"	"ENSG00000164754"	"RAD21"	"A8K0E0; hsa:5885; O60216; Q15001; Q99568"	"Cell cycle; Prion disease pathway; Regulation of sister chromatid separation at the metaphase-anaphase transition; Cohesin complex - Cornelia de Lange syndrome; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome"	"Meiotic synapsis; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; SUMOylation of DNA damage response and repair proteins; Estrogen-dependent gene expression; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"12"	"0"	"244.5"	"455.9"	"519.2"	"232.0"	"432.0"	"271.8"	"556.2"	"429.3"	"661.0"	"776.9"	"1108.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P58876"	"Histone H2B type 1-D OS=Homo sapiens OX=9606 GN=H2BC5 PE=1 SV=2"	"42"	"5"	"14"	"5"	"126"	"13.9"	"10.32"	"2498.35"	"21.95"	"5"	"5"	""	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125"	"3017"	"ENSG00000158373"	"H2BC5"	"hsa:3017; P58876"	""	"Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Estrogen-dependent gene expression; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; Meiotic recombination; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; DNA Damage/Telomere Stress Induced Senescence; Nonhomologous End-Joining (NHEJ); E3 ubiquitin ligases ubiquitinate target proteins; Amyloid fiber formation; Meiotic synapsis; HCMV Late Events; HCMV Early Events; Transcriptional regulation by small RNAs; Deposition of new CENPA-containing nucleosomes at the centromere; B-WICH complex positively regulates rRNA expression; Formation of the beta-catenin:TCF transactivating complex; Oxidative Stress Induced Senescence; HDACs deacetylate histones; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Pre-NOTCH Transcription and Translation; Senescence-Associated Secretory Phenotype (SASP); RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; HATs acetylate histones; RNA Polymerase I Promoter Escape; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Packaging Of Telomere Ends; Condensation of Prophase Chromosomes; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis"	"43"	"0"	"277.0"	"716.9"	"644.8"	"243.4"	"579.9"	"262.7"	"665.5"	"616.4"	"946.7"	"887.3"	"1359.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61313"	"60S ribosomal protein L15 OS=Homo sapiens OX=9606 GN=RPL15 PE=1 SV=2"	"24"	"5"	"14"	"5"	"204"	"24.1"	"11.62"	"2266.22"	"21.92"	"5"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00827"	"6138"	"ENSG00000174748"	"RPL15"	"hsa:6138; P39030; P41051; P61313; Q5U0C0; Q642I1; Q6IPX6; Q8WYP2; Q96C44; Q9H2E5"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"230.3"	"471.7"	"468.1"	"193.8"	"476.1"	"226.4"	"783.1"	"604.2"	"712.1"	"878.2"	"1322.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N1G4"	"Leucine-rich repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=LRRC47 PE=1 SV=1"	"12"	"5"	"11"	"5"	"583"	"63.4"	"8.28"	"1698.84"	"21.92"	"4"	"5"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	""	"other molecular function"	"Pf00560, Pf03483, Pf12799"	"57470"	"ENSG00000130764"	"LRRC47"	"hsa:57470; Q8N1G4; Q9ULN5"	""	""	"0"	"0"	"85.4"	"178.8"	"193.9"	"96.7"	"196.8"	"140.1"	"216.9"	"144.7"	"209.8"	"288.8"	"426.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16576"	"Histone-binding protein RBBP7 OS=Homo sapiens OX=9606 GN=RBBP7 PE=1 SV=1"	"13"	"7"	"15"	"1"	"425"	"47.8"	"5.05"	"3126.75"	"21.90"	"7"	"6"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400, Pf12265"	"5931"	"ENSG00000102054"	"RBBP7"	"hsa:5931; Q16576; Q5JP00"	"Retinoblastoma gene in cancer; Interactome of polycomb repressive complex 2 (PRC2) ; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"HCMV Early Events; Neddylation; Potential therapeutics for SARS; Deposition of new CENPA-containing nucleosomes at the centromere; Oxidative Stress Induced Senescence; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6; HDACs deacetylate histones; Activation of anterior HOX genes in hindbrain development during early embryogenesis; RMTs methylate histone arginines; PKMTs methylate histone lysines; HATs acetylate histones; RNA Polymerase I Transcription Initiation; PRC2 methylates histones and DNA; Defective pyroptosis; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of TP53 Activity through Acetylation"	"20"	"0"	"141.7"	"223.0"	"219.5"	"118.7"	"175.4"	"104.9"	"277.0"	"234.1"	"247.7"	"245.2"	"340.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P265"	"Disco-interacting protein 2 homolog B OS=Homo sapiens OX=9606 GN=DIP2B PE=1 SV=3"	"6"	"6"	"11"	"5"	"1576"	"171.4"	"8.09"	"1629.26"	"21.89"	"5"	"6"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"cytoskeletal activity"	"Pf00501, Pf06464"	"57609"	"ENSG00000066084"	"DIP2B"	"hsa:57609; Q6B011; Q8N1L5; Q8NB38; Q9P265"	""	""	"0"	"1"	"89.9"	"145.8"	"155.6"	"77.8"	"167.4"	"87.6"	"281.2"	"379.1"	"625.1"	"1071.2"	"1625.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49411"	"Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2"	"17"	"7"	"17"	"7"	"452"	"49.5"	"7.61"	"3172.58"	"21.84"	"6"	"7"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"488.7"	"2042.1"	"1794.9"	"347.5"	"1561.7"	"595.4"	"788.8"	"560.9"	"800.4"	"1023.1"	"1905.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62195"	"26S proteasome regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMC5 PE=1 SV=1"	"22"	"7"	"12"	"6"	"406"	"45.6"	"7.55"	"1750.77"	"21.80"	"5"	"7"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00004, Pf16450, Pf17862"	"5705"	"ENSG00000087191"	"PSMC5"	"A8K3Z3; A8K763; hsa:5705; O35051; O43208; P47210; P52915; P52916; P62195"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Pregnane X receptor pathway; Nuclear receptors meta-pathway; Alzheimer's disease"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"65"	"0"	"75.6"	"193.5"	"198.0"	"74.1"	"172.4"	"81.9"	"116.4"	"95.3"	"134.6"	"205.2"	"330.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P28340"	"DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2"	"8"	"7"	"14"	"7"	"1107"	"123.6"	"7.03"	"2021.67"	"21.77"	"5"	"7"	"DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00136, Pf03104, Pf14260"	"5424"	"ENSG00000062822"	"POLD1"	"hsa:5424; P28340; Q8NER3; Q96H98"	"Homologous recombination; Pyrimidine metabolism; DNA replication; Base excision repair; Nucleotide excision repair; DNA repair pathways, full network; Progeria-associated lipodystrophy; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Cytosolic iron-sulfur cluster assembly; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Polymerase switching on the C-strand of the telomere; Polymerase switching; Removal of the Flap Intermediate; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"27"	"0"	"114.7"	"309.3"	"275.4"	"106.0"	"274.7"	"159.0"	"276.6"	"542.5"	"625.7"	"649.7"	"791.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50502"	"Hsc70-interacting protein OS=Homo sapiens OX=9606 GN=ST13 PE=1 SV=2"	"17"	"8"	"17"	"8"	"369"	"41.3"	"5.27"	"3144.15"	"21.72"	"7"	"7"	"other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf17830, Pf18253"	"6767"	"ENSG00000100380"	"ST13"	"hsa:6767; O14999; P50502; Q2TU77"	""	"Regulation of HSF1-mediated heat shock response"	"1"	"0"	"1145.3"	"2390.4"	"2258.5"	"823.3"	"1986.1"	"1179.0"	"1043.1"	"801.1"	"1244.4"	"1766.4"	"3381.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15144"	"Actin-related protein 2/3 complex subunit 2 OS=Homo sapiens OX=9606 GN=ARPC2 PE=1 SV=1"	"19"	"6"	"10"	"6"	"300"	"34.3"	"7.36"	"1161.31"	"21.71"	"3"	"6"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity"	"Pf04045"	"10109"	"ENSG00000163466"	"ARPC2"	"hsa:10109; O15144; Q92801; Q9P1D4"	"Pathogenic Escherichia coli infection"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Clathrin-mediated endocytosis; EPHB-mediated forward signaling"	"6"	"0"	"194.3"	"356.3"	"421.2"	"194.2"	"421.0"	"239.6"	"635.0"	"655.0"	"925.1"	"1568.5"	"3835.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q04695"	"Keratin, type I cytoskeletal 17 OS=Homo sapiens OX=9606 GN=KRT17 PE=1 SV=2"	"21"	"10"	"20"	"6"	"432"	"48.1"	"5.02"	"3466.31"	"21.69"	"9"	"8"	"cell organization and biogenesis;other biological processes"	"plasma membrane;cytosol;cytoskeleton"	"other molecular function"	"Pf00038"	"3872"	"ENSG00000128422"	"KRT17"	"A5Z1M9; A5Z1N0; A5Z1N1; A5Z1N2; A6NDV6; A6NKQ2; hsa:3872; Q04695; Q6IP98; Q8N1P6"	"1p36 copy number variation syndrome; Pancreatic cancer subtypes"	"Formation of the cornified envelope"	"4"	"0"	"253.0"	"524.9"	"5334.5"	"210.9"	"213.9"	"382.2"	"398.7"	"318.2"	"527.0"	"527.1"	"696.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H9Y6"	"DNA-directed RNA polymerase I subunit RPA2 OS=Homo sapiens OX=9606 GN=POLR1B PE=1 SV=2"	"7"	"7"	"13"	"7"	"1135"	"128.1"	"7.83"	"1878.58"	"21.64"	"6"	"7"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00562, Pf04560, Pf04561, Pf04563, Pf04565, Pf06883"	"84172"	"ENSG00000125630"	"POLR1B"	"B7Z6Y7; B7Z823; F5GZX4; F8W898; hsa:84172; Q2TAM4; Q585T5; Q6ZRR2; Q9H9D3; Q9H9Y6"	"Pyrimidine metabolism; Eukaryotic transcription initiation; 2q13 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"8"	"0"	"60.0"	"142.3"	"153.7"	"69.4"	"148.8"	"83.2"	"145.8"	"213.7"	"577.8"	"927.2"	"1098.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P43487"	"Ran-specific GTPase-activating protein OS=Homo sapiens OX=9606 GN=RANBP1 PE=1 SV=1"	"24"	"5"	"13"	"5"	"201"	"23.3"	"5.29"	"1941.66"	"21.50"	"4"	"5"	"transport;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00638"	"5902"	"ENSG00000099901"	"RANBP1"	"hsa:5902; P43487; Q53EY3"	"22q11.2 copy number variation syndrome"	"Rev-mediated nuclear export of HIV RNA"	"2"	"0"	"553.6"	"1960.3"	"1939.7"	"404.9"	"1640.8"	"666.3"	"925.9"	"576.7"	"961.4"	"1013.8"	"1983.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7L014"	"Probable ATP-dependent RNA helicase DDX46 OS=Homo sapiens OX=9606 GN=DDX46 PE=1 SV=2"	"8"	"8"	"15"	"8"	"1031"	"117.3"	"9.29"	"2508.50"	"21.37"	"8"	"7"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"other membranes;nucleus"	"other molecular function"	"Pf00270, Pf00271"	"9879"	"ENSG00000145833"	"DDX46"	"hsa:9879; O94894; Q7L014; Q96EI0; Q9Y658"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"399.5"	"848.3"	"863.6"	"374.1"	"849.5"	"470.7"	"819.3"	"633.8"	"971.4"	"1433.8"	"2312.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P53582"	"Methionine aminopeptidase 1 OS=Homo sapiens OX=9606 GN=METAP1 PE=1 SV=2"	"27"	"7"	"10"	"7"	"386"	"43.2"	"7.17"	"1336.26"	"21.07"	"4"	"6"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00557, Pf15801"	"23173"	"ENSG00000164024"	"METAP1"	"B4E2E6; hsa:23173; P53582"	""	"Inactivation, recovery and regulation of the phototransduction cascade"	"1"	"0"	"67.9"	"125.0"	"134.3"	"63.8"	"121.6"	"63.1"	"152.4"	"141.4"	"205.9"	"306.3"	"608.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P15531"	"Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1"	"37"	"5"	"14"	"1"	"152"	"17.1"	"6.19"	"2638.82"	"21.02"	"5"	"5"	"DNA metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"translation activity;kinase activity;other molecular function"	"Pf00334"	"4830"	"ENSG00000239672"	"NME1"	"hsa:4830; P15531; Q6FGK3; Q86XQ2; Q9UDJ6"	"Pyrimidine metabolism"	"Interconversion of nucleotide di- and triphosphates; Azathioprine ADME; Ribavirin ADME"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99543"	"DnaJ homolog subfamily C member 2 OS=Homo sapiens OX=9606 GN=DNAJC2 PE=1 SV=4"	"12"	"6"	"11"	"6"	"621"	"72.0"	"8.70"	"1653.46"	"20.96"	"5"	"6"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"translation activity;other molecular function"	"Pf00226, Pf00249, Pf16717"	"27000"	"ENSG00000105821"	"DNAJC2"	"A4VCI0; hsa:27000; Q99543; Q9BVX1"	""	"Regulation of HSF1-mediated heat shock response"	"1"	"0"	"158.0"	"288.6"	"304.9"	"132.3"	"255.3"	"168.2"	"383.2"	"290.1"	"460.7"	"824.0"	"1515.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P2Q9"	"Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2"	"3"	"6"	"14"	"6"	"2335"	"273.4"	"8.84"	"2192.83"	"20.83"	"5"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01398, Pf08082, Pf08083, Pf08084, Pf10596, Pf10597, Pf10598, Pf12134"	"10594"	"ENSG00000174231; ENSG00000274442"	"PRPF8"	"hsa:10594; O14547; O75965; Q6P2Q9"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"3"	"0"	"307.3"	"722.2"	"754.4"	"277.3"	"666.3"	"359.1"	"731.0"	"548.2"	"890.1"	"1235.7"	"1783.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BTT0"	"Acidic leucine-rich nuclear phosphoprotein 32 family member E OS=Homo sapiens OX=9606 GN=ANP32E PE=1 SV=1"	"16"	"4"	"13"	"4"	"268"	"30.7"	"3.85"	"1934.11"	"20.77"	"4"	"4"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf14580"	"81611"	"ENSG00000143401"	"ANP32E"	"B4E0I6; E9PEA6; hsa:81611; Q5TB18; Q5TB20; Q8N1S4; Q8WWW9; Q9BTT0"	""	""	"0"	"0"	"140.6"	"275.9"	"286.5"	"150.2"	"298.0"	"185.3"	"314.9"	"229.8"	"284.9"	"322.2"	"520.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55795"	"Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1"	"16"	"6"	"15"	"1"	"449"	"49.2"	"6.30"	"2469.81"	"20.76"	"5"	"5"	"other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf00076, Pf08080"	"3188"	"ENSG00000126945"	"HNRNPH2"	"A1L400; hsa:3188; P55795; Q9HHA7"	"mRNA processing"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"3"	"0"	"10.0"	"26.9"	"30.5"	"11.3"	"31.7"	"10.3"	"25.9"	"15.8"	"23.8"	"32.9"	"42.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H3P2"	"Negative elongation factor A OS=Homo sapiens OX=9606 GN=NELFA PE=1 SV=3"	"10"	"4"	"11"	"4"	"528"	"57.2"	"9.03"	"1916.42"	"20.72"	"3"	"4"	"other biological processes"	"cytosol;nucleus"	"other molecular function"	""	"7469"	"ENSG00000185049"	"NELFA"	"A2A2T1; hsa:7469; O95392; Q9H3P2"	"Initiation of transcription and translation elongation at the HIV-1 LTR"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes"	"15"	"0"	"86.7"	"196.3"	"202.5"	"69.6"	"192.5"	"89.6"	"213.1"	"155.8"	"222.1"	"291.6"	"394.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82650"	"28S ribosomal protein S22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS22 PE=1 SV=1"	"20"	"6"	"12"	"6"	"360"	"41.3"	"7.90"	"1772.54"	"20.60"	"4"	"6"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf10245"	"56945"	"ENSG00000175110"	"MRPS22"	"hsa:56945; P82650; Q9H3I1"	"Primary ovarian insufficiency"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"4"	"0"	"172.8"	"447.1"	"456.3"	"171.0"	"396.9"	"207.5"	"301.2"	"219.3"	"352.6"	"454.1"	"676.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95881"	"Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1"	"43"	"7"	"13"	"7"	"172"	"19.2"	"5.40"	"2472.21"	"20.56"	"6"	"5"	"other biological processes"	"ER/Golgi"	"other molecular function"	"Pf13899"	"51060"	"ENSG00000117862"	"TXNDC12"	"B3KQS0; hsa:51060; O95881; Q5T1T4; Q96H50"	""	""	"0"	"0"	"1265.6"	"1816.0"	"2466.7"	"1339.7"	"2179.4"	"1674.3"	"1885.7"	"1253.8"	"1776.4"	"1757.9"	"2032.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00264"	"Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3"	"21"	"6"	"14"	"5"	"195"	"21.7"	"4.70"	"2279.05"	"20.48"	"6"	"5"	"cell organization and biogenesis;other metabolic processes;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;mitochondrion;ER/Golgi;other cell component"	"other molecular function"	"Pf00173"	"10857"	"ENSG00000101856"	"PGRMC1"	"B7Z1L3; hsa:10857; O00264; Q9UGJ9"	"Primary ovarian insufficiency"	"Neutrophil degranulation"	"2"	"1"	"299.1"	"1240.2"	"1110.6"	"231.3"	"1011.2"	"328.0"	"549.2"	"444.5"	"579.9"	"942.6"	"1577.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86V81"	"THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3"	"28"	"5"	"8"	"5"	"257"	"26.9"	"11.15"	"1475.42"	"20.35"	"4"	"4"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf13865"	"10189"	""	"ALYREF"	"hsa:10189; O43672; Q86V81"	""	"mRNA Splicing - Major Pathway; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"7"	"0"	"429.1"	"814.0"	"858.1"	"335.6"	"776.6"	"415.1"	"1473.9"	"1062.9"	"1396.9"	"1555.5"	"2145.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62841"	"40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2"	"23"	"2"	"12"	"2"	"145"	"17.0"	"10.39"	"1799.44"	"20.34"	"1"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00203"	"6209"	"ENSG00000115268"	"RPS15"	"A5D8V9; hsa:6209; P11174; P62841; Q3KRA1; Q9UDC2"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; SRP-dependent cotranslational protein targeting to membrane; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"289.3"	"693.4"	"645.3"	"310.2"	"574.0"	"302.0"	"665.1"	"535.1"	"812.8"	"985.3"	"1607.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43491"	"Band 4.1-like protein 2 OS=Homo sapiens OX=9606 GN=EPB41L2 PE=1 SV=1"	"7"	"7"	"13"	"6"	"1005"	"112.5"	"5.44"	"2031.78"	"20.32"	"6"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf04382, Pf05902, Pf08736, Pf09379, Pf09380"	"2037"	"ENSG00000079819"	"EPB41L2"	"B4DHI8; E9PPD9; hsa:2037; O43491; Q5T4F0; Q68DV2"	"Splicing factor NOVA regulated synaptic proteins"	"Neurexins and neuroligins"	"2"	"1"	"208.0"	"566.9"	"523.2"	"164.2"	"467.7"	"285.1"	"483.4"	"333.7"	"1370.0"	"3137.1"	"3812.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94903"	"Pyridoxal phosphate homeostasis protein OS=Homo sapiens OX=9606 GN=PLPBP PE=1 SV=1"	"19"	"5"	"11"	"5"	"275"	"30.3"	"7.50"	"1789.19"	"20.26"	"4"	"5"	""	"cytosol;other cell component"	"other molecular function"	"Pf01168"	"11212"	"ENSG00000147471"	"PLPBP"	"hsa:11212; O94903; Q6FI94"	""	""	"0"	"0"	"122.2"	"266.9"	"293.0"	"122.4"	"288.6"	"136.9"	"262.3"	"226.9"	"562.9"	"1350.4"	"2945.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P10599"	"Thioredoxin OS=Homo sapiens OX=9606 GN=TXN PE=1 SV=3"	"40"	"4"	"12"	"4"	"105"	"11.7"	"4.92"	"1881.74"	"20.24"	"4"	"4"	"other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00085"	"7295"	"ENSG00000136810"	"TXN"	"B1ALW1; hsa:7295; O60744; P10599; Q53X69; Q96KI3; Q9UDG5"	"Selenium micronutrient network; Folic acid network; Selenium micronutrient network ; Folic acid network; Selenium micronutrient network; TNF-alpha signaling pathway; Complement system; Nuclear receptors meta-pathway; NRF2 pathway; VEGFA-VEGFR2 signaling"	"TP53 Regulates Metabolic Genes; Detoxification of Reactive Oxygen Species; Oxidative Stress Induced Senescence; Interconversion of nucleotide di- and triphosphates; The NLRP3 inflammasome; Purinergic signaling in leishmaniasis infection; Regulation of FOXO transcriptional activity by acetylation; Protein repair"	"18"	"0"	"241.8"	"753.7"	"712.8"	"158.5"	"607.3"	"288.9"	"340.3"	"224.2"	"329.7"	"420.1"	"787.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UQB8"	"Brain-specific angiogenesis inhibitor 1-associated protein 2 OS=Homo sapiens OX=9606 GN=BAIAP2 PE=1 SV=1"	"16"	"6"	"9"	"6"	"552"	"60.8"	"8.90"	"1234.38"	"20.21"	"3"	"6"	"cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf07653, Pf08397"	"10458"	"ENSG00000175866"	"BAIAP2"	"hsa:10458; O43858; Q53HB1; Q86WC1; Q8N5C0; Q96CR7; Q9UBR3; Q9UQ43; Q9UQB8"	"Regulation of actin cytoskeleton"	"RAC1 GTPase cycle; CDC42 GTPase cycle; RAC3 GTPase cycle; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; VEGFA-VEGFR2 Pathway"	"8"	"0"	"60.6"	"71.6"	"82.8"	"32.6"	"78.9"	"50.7"	"129.1"	"126.7"	"227.5"	"421.1"	"663.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q04760"	"Lactoylglutathione lyase OS=Homo sapiens OX=9606 GN=GLO1 PE=1 SV=4"	"39"	"6"	"13"	"6"	"184"	"20.8"	"5.31"	"2093.10"	"20.19"	"5"	"6"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00903"	"2739"	"ENSG00000124767"	"GLO1"	"B2R6P7; B4DDV0; hsa:2739; P78375; Q04760; Q59EL0; Q5TZW3; Q96FC0; Q96J41"	""	"Pyruvate metabolism"	"1"	"0"	"245.1"	"1819.6"	"1445.7"	"147.8"	"1269.7"	"386.7"	"465.7"	"373.4"	"470.6"	"697.0"	"1597.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35606"	"Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2"	"8"	"6"	"13"	"6"	"906"	"102.4"	"5.27"	"2436.51"	"20.19"	"6"	"6"	"transport"	"other membranes;cytosol;ER/Golgi"	"other molecular function"	"Pf00400, Pf04053"	"9276"	"ENSG00000184432"	"COPB2"	"B4DZI8; hsa:9276; P35606"	""	"COPI-mediated anterograde transport; COPI-dependent Golgi-to-ER retrograde traffic"	"2"	"0"	"298.9"	"508.9"	"573.1"	"236.3"	"518.6"	"347.5"	"491.5"	"374.7"	"539.1"	"692.1"	"906.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46940"	"Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1"	"4"	"7"	"12"	"6"	"1657"	"189.1"	"6.48"	"2047.32"	"20.02"	"6"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00307, Pf00612, Pf00616, Pf03836"	"8826"	"ENSG00000140575"	"IQGAP1"	"A7MBM3; hsa:8826; P46940"	"VEGFA-VEGFR2 signaling; Ebola virus infection in host; Ciliary landscape; EGF/EGFR signaling pathway; Regulation of actin cytoskeleton; G13 signaling pathway"	"Neutrophil degranulation; RHOA GTPase cycle; RHOC GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RHO GTPases activate IQGAPs; RAC2 GTPase cycle; RHOV GTPase cycle; Signaling by BRAF and RAF1 fusions; RHOU GTPase cycle; Nephrin family interactions; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants"	"25"	"0"	"201.9"	"543.3"	"506.8"	"191.6"	"498.1"	"249.7"	"339.2"	"312.7"	"417.8"	"599.3"	"941.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96SB8"	"Structural maintenance of chromosomes protein 6 OS=Homo sapiens OX=9606 GN=SMC6 PE=1 SV=2"	"7"	"7"	"15"	"7"	"1091"	"126.2"	"6.99"	"2948.67"	"19.94"	"6"	"6"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02463"	"79677"	"ENSG00000163029"	"SMC6"	"A8K8Q6; D6W518; hsa:79677; Q05BV4; Q96SB8; Q9H0X3; Q9H6M0"	""	"SUMOylation of DNA damage response and repair proteins"	"1"	"0"	"143.2"	"231.1"	"274.1"	"144.4"	"269.6"	"196.4"	"389.0"	"294.6"	"456.1"	"690.2"	"871.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P81605"	"Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2"	"48"	"7"	"15"	"7"	"110"	"11.3"	"6.54"	"2577.35"	"19.92"	"6"	"5"	"protein metabolism;stress response;transport;other biological processes"	"non-structural extracellular;other membranes"	"transporter activity;other molecular function"	"Pf15291"	"117159"	"ENSG00000161634"	"DCD"	"A5JHP2; A5JHP3; hsa:117159; P58461; P81605; Q53YJ2"	""	"Antimicrobial peptides"	"1"	"0"	"1031.3"	"994.0"	"1684.8"	"1451.6"	"1253.4"	"688.7"	"1974.0"	"1925.7"	"2491.8"	"2290.5"	"2452.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60900"	"Proteasome subunit alpha type-6 OS=Homo sapiens OX=9606 GN=PSMA6 PE=1 SV=1"	"30"	"6"	"10"	"6"	"246"	"27.4"	"6.76"	"1656.69"	"19.86"	"4"	"6"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00227, Pf10584"	"5687"	"ENSG00000100902"	"PSMA6"	"B2R7J9; B4DQR4; B4DXJ9; hsa:5687; P34062; P60900; Q6IB60"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Regulation of expression of SLITs and ROBOs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"62"	"0"	"171.7"	"267.3"	"315.8"	"139.4"	"277.9"	"167.8"	"343.5"	"297.5"	"360.9"	"521.6"	"870.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P12004"	"Proliferating cell nuclear antigen OS=Homo sapiens OX=9606 GN=PCNA PE=1 SV=1"	"28"	"6"	"11"	"6"	"261"	"28.8"	"4.69"	"1595.09"	"19.78"	"5"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00705, Pf02747"	"5111"	"ENSG00000132646"	"PCNA"	"B2R897; D3DW02; hsa:5111; P12004"	"Cell cycle; Retinoblastoma gene in cancer; Primary focal segmental glomerulosclerosis (FSGS); Oxidative damage response; EGF/EGFR signaling pathway; G1 to S cell cycle control; DNA replication; Hepatitis B infection; Base excision repair; Nucleotide excision repair; 7q11.23 copy number variation syndrome; DNA repair pathways, full network; 16p11.2 proximal deletion syndrome; p53 transcriptional gene network; Nucleotide excision repair in xeroderma pigmentosum ; Urotensin-II-mediated signaling pathway; DNA mismatch repair; 10q11.21q11.23 copy number variation syndrome; A network map of Macrophage-stimulating protein (MSP) signaling"	"HDR through Homologous Recombination (HRR); E3 ubiquitin ligases ubiquitinate target proteins; SUMOylation of DNA replication proteins; Termination of translesion DNA synthesis; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; G1/S-Specific Transcription; Recognition of DNA damage by PCNA-containing replication complex; Transcription of E2F targets under negative control by DREAM complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Polymerase switching on the C-strand of the telomere; Polymerase switching; Removal of the Flap Intermediate; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"45"	"0"	"173.6"	"886.6"	"699.9"	"156.8"	"637.7"	"216.0"	"437.8"	"341.4"	"428.7"	"572.0"	"1096.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NZT1"	"Calmodulin-like protein 5 OS=Homo sapiens OX=9606 GN=CALML5 PE=1 SV=2"	"38"	"4"	"7"	"4"	"146"	"15.9"	"4.44"	"612.37"	"19.77"	"2"	"4"	"signal transduction;other biological processes"	"non-structural extracellular;other cell component"	"enzyme regulator activity;other molecular function"	"Pf13499"	"51806"	"ENSG00000178372"	"CALML5"	"hsa:51806; Q5SQI3; Q8IXU8; Q9NZT1"	"Alzheimer's disease and miRNA effects; Ras signaling; Melanoma; Alzheimer's disease"	"Neutrophil degranulation"	"5"	"0"	"146.3"	"192.8"	"391.7"	"112.0"	"200.3"	"156.3"	"1310.0"	"1071.9"	"1333.8"	"1264.2"	"1517.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q07065"	"Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2"	"12"	"6"	"11"	"6"	"602"	"66.0"	"5.92"	"2282.04"	"19.49"	"6"	"5"	""	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	""	""	"10970"	"ENSG00000136026"	"CKAP4"	"hsa:10970; Q07065; Q504S5; Q53ES6"	""	"Neutrophil degranulation; RND2 GTPase cycle; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; RND3 GTPase cycle; Surfactant metabolism"	"6"	"0"	"224.4"	"598.8"	"602.0"	"211.0"	"554.7"	"270.3"	"380.5"	"326.0"	"493.7"	"675.0"	"1023.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P00338"	"L-lactate dehydrogenase A chain OS=Homo sapiens OX=9606 GN=LDHA PE=1 SV=2"	"20"	"7"	"15"	"6"	"332"	"36.7"	"8.27"	"2914.53"	"19.48"	"7"	"5"	"other metabolic processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00056, Pf02866"	"3939"	"ENSG00000134333; ENSG00000288299"	"LDHA"	"B4DKQ2; B7Z5E3; D3DQY3; F8W819; hsa:3939; P00338; Q53G53; Q6IBM7; Q6ZNV1; Q9UDE8; Q9UDE9"	"Cori cycle; HIF1A and PPARG regulation of glycolysis; Photodynamic therapy-induced HIF-1 survival signaling; VEGFA-VEGFR2 signaling; Amino acid metabolism; Clear cell renal cell carcinoma pathways; PI3K/AKT/mTOR - vitamin D3 signaling; Metabolic reprogramming in colon cancer; Aerobic glycolysis; Glycolysis in senescence; Orexin receptor pathway; CCL18 signaling pathway; Glucose metabolism in triple-negative breast cancer cells; Lactate shuttle in glial cells; Glycolysis and gluconeogenesis; A network map of Macrophage-stimulating protein (MSP) signaling"	"Pyruvate metabolism"	"17"	"0"	"292.2"	"3205.5"	"2176.0"	"78.7"	"1851.9"	"384.9"	"522.5"	"412.2"	"618.4"	"858.7"	"2083.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15370"	"Elongin-B OS=Homo sapiens OX=9606 GN=ELOB PE=1 SV=1"	"53"	"6"	"11"	"6"	"118"	"13.1"	"4.88"	"1835.73"	"19.44"	"5"	"6"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00240"	"6923"	"ENSG00000103363"	"ELOB"	"B7WPD3; hsa:6923; Q15370"	"Dual hijack model of Vif in HIV infection; Type 2 papillary renal cell carcinoma; Hijack of ubiquitination by SARS-CoV-2; Modulators of TCR signaling and T cell activation"	"Regulation of expression of SLITs and ROBOs; Antigen processing: Ubiquitination & Proteasome degradation; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Vif-mediated degradation of APOBEC3G; Neddylation; Inactivation of CSF3 (G-CSF) signaling; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes"	"21"	"0"	"443.1"	"857.8"	"887.6"	"365.1"	"858.9"	"495.0"	"701.7"	"507.6"	"740.6"	"949.8"	"1393.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15637"	"Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4"	"9"	"5"	"11"	"5"	"639"	"68.3"	"8.98"	"1816.12"	"19.44"	"4"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"translational apparatus;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf00098, Pf16275"	"7536"	"ENSG00000168066"	"SF1"	"B7Z1Q1; C9JJE2; hsa:7536; Q14818; Q14819; Q15637; Q15913; Q8IY00; Q92744; Q92745; Q969H7; Q9BW01; Q9UEI0"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"388.8"	"658.5"	"654.0"	"318.8"	"704.1"	"426.2"	"752.0"	"584.3"	"823.9"	"1004.5"	"1390.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14314"	"Glucosidase 2 subunit beta OS=Homo sapiens OX=9606 GN=PRKCSH PE=1 SV=2"	"13"	"8"	"16"	"8"	"528"	"59.4"	"4.41"	"2774.37"	"19.42"	"8"	"7"	"protein metabolism;other metabolic processes;developmental processes;signal transduction"	"ER/Golgi;other cell component"	"other molecular function"	"Pf12999, Pf13015, Pf13202"	"5589"	"ENSG00000130175"	"PRKCSH"	"A8K318; hsa:5589; P14314; Q96BU9; Q96D06; Q9P0W9"	""	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Advanced glycosylation endproduct receptor signaling; Maturation of spike protein; Calnexin/calreticulin cycle; Maturation of spike protein"	"7"	"0"	"422.3"	"1415.4"	"1404.9"	"348.1"	"1226.1"	"579.1"	"737.2"	"579.7"	"939.8"	"1228.6"	"2189.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P36873"	"Serine/threonine-protein phosphatase PP1-gamma catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CC PE=1 SV=1"	"24"	"6"	"11"	"2"	"323"	"37.0"	"6.54"	"1936.85"	"19.23"	"5"	"6"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00149, Pf16891"	"5501"	"ENSG00000186298"	"PPP1CC"	"hsa:5501; P36873"	"Common pathways underlying drug addiction; Focal adhesion; Hippo-Merlin signaling dysregulation; Neuroinflammation and glutamatergic signaling"	"Separation of Sister Chromatids; Triglyceride catabolism; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Circadian Clock; RAF activation; SHOC2 M1731 mutant abolishes MRAS complex function; Gain-of-function MRAS complexes activate RAF signaling; Downregulation of TGF-beta receptor signaling"	"16"	"0"	"152.4"	"248.0"	"344.6"	"124.5"	"279.5"	"161.6"	"455.2"	"362.1"	"475.1"	"555.5"	"886.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13409"	"Cytoplasmic dynein 1 intermediate chain 2 OS=Homo sapiens OX=9606 GN=DYNC1I2 PE=1 SV=3"	"12"	"6"	"10"	"6"	"638"	"71.4"	"5.20"	"1618.54"	"19.22"	"4"	"6"	"transport;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400, Pf11540"	"1781"	"ENSG00000077380"	"DYNC1I2"	"B7ZA04; D3DPD4; D3DPD5; D3DPD6; hsa:1781; Q13409; Q32LY9; Q53S84; Q5BJF8; Q7Z4X1; Q96NG7; Q96S87; Q9BXZ5; Q9NT58"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein"	"Separation of Sister Chromatids; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; RHO GTPases Activate Formins; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; HCMV Early Events; Aggrephagy; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"21"	"0"	"241.5"	"447.2"	"561.8"	"212.8"	"465.7"	"237.5"	"620.8"	"470.2"	"701.7"	"864.5"	"1284.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60866"	"40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1"	"31"	"5"	"15"	"5"	"119"	"13.4"	"9.94"	"2452.69"	"19.05"	"5"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00338"	"6224"	"ENSG00000008988"	"RPS20"	"B2R4F4; B4DW28; hsa:6224; P17075; P60866; Q5M8S9"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"171.8"	"386.1"	"356.0"	"146.3"	"333.1"	"190.5"	"437.7"	"372.3"	"510.9"	"758.2"	"1085.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BRP8"	"Partner of Y14 and mago OS=Homo sapiens OX=9606 GN=PYM1 PE=1 SV=1"	"30"	"4"	"10"	"4"	"204"	"22.6"	"9.45"	"1725.81"	"18.99"	"4"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity"	"Pf09282"	"84305"	"ENSG00000170473"	"PYM1"	"B6ZDM5; hsa:84305; Q8IXJ8; Q8N8E7; Q9BRP8"	""	""	"0"	"0"	"104.3"	"194.8"	"196.3"	"97.9"	"202.2"	"103.7"	"260.6"	"243.4"	"312.0"	"480.4"	"746.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99733"	"Nucleosome assembly protein 1-like 4 OS=Homo sapiens OX=9606 GN=NAP1L4 PE=1 SV=1"	"12"	"4"	"11"	"3"	"375"	"42.8"	"4.69"	"1555.84"	"18.90"	"3"	"4"	"cell organization and biogenesis"	"nucleus;other cell component"	"other molecular function"	"Pf00956"	"4676"	"ENSG00000205531; ENSG00000273562"	"NAP1L4"	"B2R6J4; F5HFY4; hsa:4676; Q99733"	""	""	"0"	"0"	"114.2"	"456.0"	"382.1"	"96.4"	"315.9"	"122.8"	"277.5"	"221.0"	"307.0"	"403.8"	"745.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96T37"	"RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2"	"6"	"5"	"10"	"5"	"977"	"107.1"	"10.08"	"1509.28"	"18.89"	"3"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"other membranes;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf07744"	"64783"	"ENSG00000162775"	"RBM15"	"A1A693; hsa:64783; Q3ZB86; Q4V760; Q5D058; Q5T613; Q86VW9; Q96PE4; Q96SC5; Q96SC6; Q96SC9; Q96SD0; Q96T37; Q96T38; Q9BRA5; Q9H6R8; Q9H9Y0"	""	""	"0"	"0"	"72.1"	"135.9"	"151.5"	"60.0"	"148.4"	"86.2"	"211.5"	"241.7"	"424.3"	"658.4"	"1224.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P48634"	"Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3"	"3"	"6"	"10"	"5"	"2157"	"228.7"	"9.45"	"2082.22"	"18.76"	"5"	"5"	"other biological processes"	"plasma membrane;other membranes;cytosol;nucleus"	""	"Pf07001"	"7916"	"ENSG00000204469; ENSG00000206427; ENSG00000225164; ENSG00000225748; ENSG00000226618; ENSG00000231370; ENSG00000231825"	"PRRC2A"	"B0UX77; B0UZE9; B0UZL3; hsa:7916; O95875; P48634; Q05BK4; Q4LE37; Q5SQ29; Q5SQ30; Q5ST84; Q5STX6; Q5STX7; Q68DW9; Q6P9P7; Q6PIN1; Q8MGQ9; Q96QC6"	""	""	"0"	"0"	"189.3"	"263.7"	"313.1"	"173.2"	"331.8"	"211.9"	"704.9"	"467.6"	"649.3"	"641.9"	"855.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46783"	"40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1"	"43"	"8"	"25"	"8"	"165"	"18.9"	"10.15"	"5931.29"	"18.72"	"6"	"6"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf03501"	"6204"	"ENSG00000124614"	"RPS10"	"B2R4E3; hsa:6204; P46783; Q5TZC0"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; SRP-dependent cotranslational protein targeting to membrane; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"1524.5"	"2899.2"	"2999.6"	"1422.6"	"2692.5"	"1656.8"	"5010.6"	"4092.8"	"5484.1"	"6022.9"	"7899.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15372"	"Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1"	"22"	"6"	"10"	"6"	"352"	"39.9"	"6.54"	"1304.77"	"18.70"	"4"	"6"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01398, Pf19445"	"8667"	"ENSG00000147677"	"EIF3H"	"hsa:8667; O15372"	"Translation factors; VEGFA-VEGFR2 signaling; Measles virus infection; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"10"	"0"	"235.6"	"429.1"	"529.2"	"235.9"	"486.6"	"309.6"	"398.1"	"297.1"	"466.0"	"573.9"	"843.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P20042"	"Eukaryotic translation initiation factor 2 subunit 2 OS=Homo sapiens OX=9606 GN=EIF2S2 PE=1 SV=2"	"23"	"6"	"9"	"6"	"333"	"38.4"	"5.80"	"2152.83"	"18.64"	"4"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01873"	"8894"	"ENSG00000125977"	"EIF2S2"	"hsa:8894; P20042; Q9BVU0; Q9UJE4"	"Translation factors; Brain-derived neurotrophic factor (BDNF) signaling pathway; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell; Primary ovarian insufficiency"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; ABC-family proteins mediated transport; Response of EIF2AK1 (HRI) to heme deficiency; PERK regulates gene expression; Recycling of eIF2:GDP; Response of EIF2AK4 (GCN2) to amino acid deficiency"	"14"	"0"	"109.1"	"208.5"	"236.6"	"78.9"	"224.1"	"110.2"	"381.9"	"265.2"	"449.1"	"705.4"	"1281.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P37837"	"Transaldolase OS=Homo sapiens OX=9606 GN=TALDO1 PE=1 SV=2"	"20"	"7"	"12"	"7"	"337"	"37.5"	"6.81"	"1845.26"	"18.62"	"6"	"6"	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00923"	"6888"	"ENSG00000177156"	"TALDO1"	"B2R8M2; hsa:6888; O00751; P37837; Q8WV32; Q8WZ45"	"Pentose phosphate metabolism; Cori cycle; Metabolic reprogramming in colon cancer"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; NFE2L2 regulates pentose phosphate pathway genes; Pentose phosphate pathway; Insulin effects increased synthesis of Xylulose-5-Phosphate; TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P; TALDO1 deficiency: failed conversion of  Fru(6)P, E4P to SH7P, GA3P"	"9"	"0"	"213.6"	"1566.7"	"1242.5"	"194.9"	"1137.1"	"314.5"	"524.5"	"381.8"	"546.9"	"720.2"	"1450.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22314"	"Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3"	"7"	"6"	"13"	"6"	"1058"	"117.8"	"5.76"	"2865.27"	"18.62"	"6"	"5"	"protein metabolism;other metabolic processes;stress response"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00899, Pf09358, Pf10585, Pf16190, Pf16191"	"7317"	"ENSG00000130985"	"UBA1"	"hsa:7317; P22314; Q5JRR8; Q96E13"	"Proteasome degradation; Parkin-ubiquitin proteasomal system pathway; Parkinson's disease pathway"	"Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Antigen processing: Ubiquitination & Proteasome degradation"	"5"	"0"	"244.8"	"1578.2"	"1342.2"	"167.0"	"1263.5"	"339.2"	"547.8"	"372.5"	"541.8"	"647.5"	"1424.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P16949"	"Stathmin OS=Homo sapiens OX=9606 GN=STMN1 PE=1 SV=3"	"31"	"4"	"9"	"4"	"149"	"17.3"	"5.97"	"1487.23"	"18.61"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf00836"	"3925"	"ENSG00000117632"	"STMN1"	"A2A2D1; B2R4E7; B7Z8N4; D3DPJ5; hsa:3925; P16949"	"Microtubule cytoskeleton regulation; Retinoblastoma gene in cancer; RAC1/PAK1/p38/MMP2 pathway; MAPK signaling pathway; EGF/EGFR signaling pathway; IL-18 signaling pathway"	"Nuclear signaling by ERBB4"	"7"	"0"	"153.8"	"564.4"	"588.0"	"107.5"	"604.7"	"201.4"	"317.1"	"207.2"	"311.3"	"384.2"	"695.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P28070"	"Proteasome subunit beta type-4 OS=Homo sapiens OX=9606 GN=PSMB4 PE=1 SV=4"	"20"	"3"	"8"	"3"	"264"	"29.2"	"5.97"	"971.24"	"18.58"	"2"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00227"	"5692"	"ENSG00000159377"	"PSMB4"	"B2R9L3; hsa:5692; P28070; P31148; Q5SZS5; Q6IBI4; Q969L6"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Regulation of expression of SLITs and ROBOs; Regulation of PTEN stability and activity; KEAP1-NFE2L2 pathway; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Neddylation; Interleukin-1 signaling; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"62"	"0"	"144.6"	"294.9"	"350.4"	"123.4"	"364.1"	"116.4"	"415.6"	"335.0"	"452.0"	"634.5"	"978.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13838"	"Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1"	"17"	"6"	"13"	"6"	"428"	"49.0"	"5.67"	"1950.64"	"18.58"	"5"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"7919"	"ENSG00000198563; ENSG00000215425; ENSG00000225073; ENSG00000225859; ENSG00000229496; ENSG00000230624; ENSG00000235439"	"DDX39B"	"B0S8C0; hsa:7919; O43496; Q0EFA1; Q13838; Q2L6F9; Q53GL9; Q5RJ64; Q5RJ66; Q5ST94; Q5STB4; Q5STB5; Q5STB7; Q5STB8; Q5STU4; Q5STU5; Q5STU6; Q5STU8; Q71V76"	""	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; RHOBTB2 GTPase cycle"	"5"	"0"	"106.2"	"899.9"	"666.9"	"75.4"	"513.8"	"161.4"	"257.6"	"186.2"	"254.9"	"343.2"	"677.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00231"	"26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3"	"19"	"6"	"11"	"6"	"422"	"47.4"	"6.48"	"1721.31"	"18.52"	"5"	"6"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf01399, Pf18055, Pf18503"	"5717"	"ENSG00000108671"	"PSMD11"	"A8K3I7; E1P663; hsa:5717; O00231; O00495; Q53FT5"	"Proteasome degradation; Parkin-ubiquitin proteasomal system pathway; VEGFA-VEGFR2 signaling"	"Separation of Sister Chromatids; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"63"	"0"	"318.2"	"680.6"	"648.3"	"287.1"	"586.2"	"359.9"	"451.4"	"356.7"	"515.6"	"658.3"	"980.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5T8P6"	"RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3"	"6"	"6"	"11"	"6"	"1007"	"113.5"	"9.16"	"2689.36"	"18.51"	"6"	"5"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf01480"	"64062"	"ENSG00000139746"	"RBM26"	"B4DZE0; hsa:64062; Q2NKM2; Q2NKQ2; Q5CZH8; Q5T8P5; Q5T8P6; Q5T8P8; Q5U5P5; Q5W0G7; Q8N3H5; Q96K92; Q96SZ3; Q9H2F8; Q9H7F9; Q9P1G7"	""	""	"0"	"0"	"192.4"	"521.4"	"480.7"	"190.5"	"429.4"	"241.5"	"451.6"	"326.6"	"507.9"	"689.6"	"1087.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9ULP9"	"TBC1 domain family member 24 OS=Homo sapiens OX=9606 GN=TBC1D24 PE=1 SV=2"	"9"	"4"	"9"	"4"	"559"	"62.9"	"7.36"	"1661.53"	"18.46"	"3"	"4"	"cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;other cell component"	"enzyme regulator activity"	"Pf00566, Pf07534"	"57465"	"ENSG00000162065"	"TBC1D24"	"A0JNW3; B9A6M6; hsa:57465; Q2KJ08; Q9ULP9"	""	"TBC/RABGAPs"	"1"	"0"	"33.1"	"54.9"	"70.4"	"42.2"	"89.5"	"56.7"	"100.8"	"155.0"	"296.7"	"501.5"	"835.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46821"	"Microtubule-associated protein 1B OS=Homo sapiens OX=9606 GN=MAP1B PE=1 SV=2"	"2"	"5"	"9"	"4"	"2468"	"270.5"	"4.81"	"1687.98"	"18.28"	"4"	"5"	"cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00414"	"4131"	"ENSG00000131711"	"MAP1B"	"A2BDK5; hsa:4131; P46821"	"Microtubule cytoskeleton regulation; Fragile X syndrome; Neurogenesis regulation in the olfactory epithelium"	""	"3"	"1"	"208.0"	"351.4"	"371.9"	"169.2"	"361.2"	"215.8"	"628.7"	"395.6"	"592.7"	"692.1"	"983.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15185"	"Prostaglandin E synthase 3 OS=Homo sapiens OX=9606 GN=PTGES3 PE=1 SV=1"	"38"	"5"	"12"	"5"	"160"	"18.7"	"4.54"	"2385.45"	"18.20"	"5"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf04969"	"10728"	"ENSG00000110958"	"PTGES3"	"A8K7D0; B4DHP2; B4DP11; B4DP21; hsa:10728; Q15185; Q8WU70"	"Aryl hydrocarbon receptor pathway; Glucocorticoid receptor pathway; Nuclear receptors meta-pathway"	"Estrogen-dependent gene expression; Potential therapeutics for SARS; HSF1 activation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Aryl hydrocarbon receptor signalling; Synthesis of Prostaglandins (PG) and Thromboxanes (TX); Attenuation phase"	"11"	"0"	"290.4"	"1405.1"	"1140.1"	"207.9"	"1103.6"	"432.4"	"643.1"	"436.2"	"593.9"	"708.0"	"1400.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62861"	"40S ribosomal protein S30 OS=Homo sapiens OX=9606 GN=FAU PE=1 SV=1"	"20"	"3"	"11"	"3"	"59"	"6.6"	"12.15"	"1574.78"	"18.09"	"3"	"3"	"protein metabolism;other metabolic processes;stress response"	"non-structural extracellular;cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf04758"	""	"ENSCHIG00000017446; ENSJHYG00000000624; ENSLLEG00000000574"	"Fau; FAU"	"A0A452F0A8; A0A7L0YXB0; A0A8C5IE60; A0A8C5LQJ8; P0C2F0; P62860; P62863; P62864; P62866; P62867; Q05472; Q5RC12; Q8HYI8; Q920W7; Q95261"	""	""	"0"	"0"	"256.7"	"436.3"	"428.6"	"230.7"	"429.1"	"254.7"	"691.1"	"638.3"	"774.6"	"906.2"	"1127.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IX12"	"Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2"	"4"	"4"	"11"	"4"	"1150"	"132.7"	"5.76"	"1921.02"	"18.07"	"4"	"3"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02037, Pf14443, Pf14444, Pf19256, Pf19257"	"55749"	"ENSG00000060339"	"CCAR1"	"A0JLT7; A1L4P7; A8K9D4; B4DNP8; B4DRK8; hsa:55749; Q32NE3; Q5EBM3; Q5VUP6; Q6PIZ0; Q6X935; Q8IX12; Q9H8N4; Q9NVA7; Q9NVQ0; Q9NWM6"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"320.9"	"515.7"	"522.5"	"313.3"	"534.8"	"304.6"	"854.1"	"639.3"	"873.6"	"976.6"	"1178.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NR30"	"Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5"	"10"	"7"	"13"	"6"	"783"	"87.3"	"9.28"	"2432.22"	"18.06"	"6"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf08152"	"9188"	"ENSG00000165732"	"DDX21"	"B2RDL0; hsa:9188; Q13436; Q5VX41; Q68D35; Q9NR30"	""	"B-WICH complex positively regulates rRNA expression; Major pathway of rRNA processing in the nucleolus and cytosol"	"2"	"0"	"178.8"	"375.2"	"380.3"	"164.7"	"337.0"	"197.2"	"358.8"	"278.4"	"372.7"	"453.7"	"686.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6PKG0"	"La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2"	"7"	"7"	"12"	"7"	"1096"	"123.4"	"8.82"	"2146.37"	"18.02"	"6"	"6"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf05383"	"23367"	"ENSG00000155506"	"LARP1"	"hsa:23367; O94836; Q6PKG0; Q8N4M2; Q8NB73; Q9UFD7"	"Perturbations to host-cell autophagy, induced by SARS-CoV-2 proteins; SARS-CoV-2 innate immunity evasion and cell-specific immune response; Network map of SARS-CoV-2 signaling pathway"	"SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"4"	"0"	"423.2"	"839.2"	"883.6"	"344.6"	"832.3"	"455.0"	"835.9"	"601.6"	"875.8"	"993.2"	"1494.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51858"	"Hepatoma-derived growth factor OS=Homo sapiens OX=9606 GN=HDGF PE=1 SV=1"	"29"	"6"	"11"	"6"	"240"	"26.8"	"4.73"	"2556.28"	"18.02"	"6"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;signal transduction;other biological processes"	"nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00855"	"3068"	"ENSG00000143321"	"HDGF"	"B3KU21; D3DVC9; hsa:3068; P51858; Q5SZ07; Q5SZ08; Q5SZ09"	"IL-18 signaling pathway"	"XBP1(S) activates chaperone genes"	"2"	"0"	"194.3"	"1189.0"	"1106.2"	"118.0"	"959.2"	"289.0"	"540.5"	"379.5"	"513.2"	"650.9"	"1357.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7L2E3"	"ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1"	"5"	"5"	"12"	"5"	"1194"	"133.9"	"8.78"	"2004.03"	"17.77"	"5"	"5"	"cell organization and biogenesis;developmental processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"22907"	"ENSG00000132153"	"DHX30"	"A8K5F1; hsa:22907; O94965; Q7L2E3; Q7Z753; Q96CH4; Q9NUQ0"	""	""	"0"	"0"	"82.2"	"259.9"	"223.1"	"76.6"	"222.1"	"92.4"	"189.7"	"145.5"	"218.6"	"266.4"	"380.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15393"	"Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4"	"7"	"8"	"13"	"8"	"1217"	"135.5"	"5.26"	"1742.64"	"17.74"	"6"	"7"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03178, Pf10433"	"23450"	"ENSG00000189091"	"SF3B3"	"hsa:23450; Q15393; Q6NTI8; Q96GC0; Q9BPY2; Q9UFX7; Q9UJ29"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"3"	"0"	"422.5"	"849.1"	"842.9"	"363.5"	"809.5"	"459.0"	"726.5"	"518.1"	"744.0"	"968.3"	"1397.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43447"	"Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1"	"28"	"5"	"11"	"5"	"177"	"19.2"	"8.07"	"1819.05"	"17.71"	"5"	"5"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00160"	"10465"	"ENSG00000171960"	"PPIH"	"A6NNE7; hsa:10465; O43447"	""	"mRNA Splicing - Major Pathway; SARS-CoV-1 activates/modulates innate immune responses"	"2"	"0"	"297.8"	"667.6"	"635.2"	"278.0"	"646.7"	"341.9"	"514.4"	"432.1"	"616.2"	"990.1"	"1724.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P78406"	"mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1"	"17"	"6"	"9"	"6"	"368"	"40.9"	"7.83"	"1168.59"	"17.70"	"3"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00400"	"8480"	"ENSG00000101146"	"RAE1"	"A8K882; hsa:8480; O15306; P78406; Q3SYL7; Q5TCH8; Q6V708; Q9H100; Q9NQM6"	"IL-18 signaling pathway; SARS-CoV-2 innate immunity evasion and cell-specific immune response"	"ISG15 antiviral mechanism; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Transcriptional regulation by small RNAs; Viral Messenger RNA Synthesis; Regulation of HSF1-mediated heat shock response; HCMV Late Events; HCMV Early Events; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus"	"30"	"0"	"626.9"	"829.7"	"901.2"	"474.5"	"967.4"	"639.4"	"1073.8"	"1063.6"	"1551.6"	"1787.7"	"3353.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15181"	"Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2"	"25"	"5"	"8"	"5"	"289"	"32.6"	"5.86"	"854.93"	"17.63"	"3"	"5"	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00719"	"5464"	"ENSG00000180817"	"PPA1"	"hsa:5464; Q15181; Q2M348; Q5SQT7; Q6P7P4; Q9UQJ5; Q9Y5B1"	""	"Cytosolic tRNA aminoacylation; Pyrophosphate hydrolysis"	"2"	"0"	"129.6"	"800.9"	"628.1"	"122.3"	"580.7"	"170.6"	"297.8"	"224.0"	"283.2"	"432.0"	"935.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75475"	"PC4 and SFRS1-interacting protein OS=Homo sapiens OX=9606 GN=PSIP1 PE=1 SV=1"	"16"	"7"	"12"	"7"	"530"	"60.1"	"9.13"	"2499.73"	"17.54"	"7"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00855, Pf11467"	"11168"	"ENSG00000164985"	"PSIP1"	"D3DRI9; hsa:11168; O00256; O75475; O95368; Q6P391; Q86YB9; Q9NZI3; Q9UER6"	"MECP2 and associated Rett syndrome"	"Vpr-mediated nuclear import of PICs; Formation of WDR5-containing histone-modifying complexes; 2-LTR circle formation; Integration of viral DNA into host genomic DNA; Autointegration results in viral DNA circles; APOBEC3G mediated resistance to HIV-1 infection"	"8"	"0"	"239.2"	"463.8"	"502.8"	"208.2"	"460.9"	"259.7"	"608.1"	"402.4"	"617.4"	"791.2"	"1336.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46013"	"Proliferation marker protein Ki-67 OS=Homo sapiens OX=9606 GN=MKI67 PE=1 SV=2"	"3"	"6"	"11"	"6"	"3256"	"358.5"	"9.45"	"1591.08"	"17.46"	"5"	"6"	"cell cycle OR cell proliferation;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00498, Pf08065, Pf15276"	"4288"	"ENSG00000148773"	"MKI67"	"hsa:4288; P46013; Q5VWH2"	"Primary focal segmental glomerulosclerosis (FSGS)"	""	"1"	"0"	"228.1"	"385.4"	"364.4"	"208.6"	"381.7"	"228.3"	"428.6"	"325.9"	"460.8"	"538.8"	"717.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P83881"	"60S ribosomal protein L36a OS=Homo sapiens OX=9606 GN=RPL36A PE=1 SV=2"	"36"	"7"	"12"	"2"	"106"	"12.4"	"10.58"	"1591.16"	"17.46"	"5"	"7"	"protein metabolism;other metabolic processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;translational apparatus"	"other molecular function"	"Pf00935"	"6173"	"ENSG00000241343"	"RPL36A"	"hsa:6173; P09896; P10661; P83881; Q08ES5; Q5J9I6"	"Cytoplasmic ribosomal proteins"	"GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"5"	"776.4"	"1186.4"	"1347.6"	"638.3"	"1345.1"	"755.3"	"2883.5"	"1868.6"	"2497.4"	"2637.1"	"3497.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P36542"	"ATP synthase subunit gamma, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1C PE=1 SV=1"	"20"	"6"	"11"	"6"	"298"	"33.0"	"9.22"	"1597.66"	"17.43"	"4"	"5"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf00231"	"509"	"ENSG00000165629"	"ATP5F1C"	"A8KA31; hsa:509; P36542; Q5VYP3; Q6I9V2; Q96AS8"	"Electron transport chain: OXPHOS system in mitochondria"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"3"	"0"	"243.2"	"601.3"	"604.1"	"222.1"	"563.7"	"287.1"	"429.8"	"352.0"	"512.9"	"698.6"	"1114.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15344"	"E3 ubiquitin-protein ligase Midline-1 OS=Homo sapiens OX=9606 GN=MID1 PE=1 SV=1"	"9"	"4"	"8"	"4"	"667"	"75.2"	"6.80"	"899.78"	"17.38"	"2"	"4"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00041, Pf00622, Pf00643, Pf13445, Pf13765, Pf18568"	"4281"	"ENSG00000101871"	"MID1"	"B2RCG2; hsa:4281; O15344; O75361; Q9BZX5"	""	"Interferon gamma signaling"	"1"	"0"	"147.9"	"232.2"	"302.5"	"122.1"	"291.3"	"169.7"	"630.7"	"663.9"	"1338.2"	"1549.5"	"1959.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52434"	"DNA-directed RNA polymerases I, II, and III subunit RPABC3 OS=Homo sapiens OX=9606 GN=POLR2H PE=1 SV=4"	"26"	"3"	"10"	"3"	"150"	"17.1"	"4.68"	"1944.19"	"17.38"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf03870"	"5437"	"ENSG00000163882"	"POLR2H"	"C9J413; C9JBJ6; C9JCU7; C9JUA8; hsa:5437; P52434; P53802; Q969R0"	"Pyrimidine metabolism; Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"mRNA Splicing - Major Pathway; Estrogen-dependent gene expression; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; B-WICH complex positively regulates rRNA expression; Formation of the Early Elongation Complex; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Abortive elongation of HIV-1 transcript in the absence of Tat; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; mRNA Splicing - Minor Pathway; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"57"	"0"	"55.5"	"142.7"	"135.4"	"46.7"	"139.7"	"64.5"	"132.8"	"143.4"	"358.2"	"487.1"	"567.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P84098"	"60S ribosomal protein L19 OS=Homo sapiens OX=9606 GN=RPL19 PE=1 SV=1"	"23"	"7"	"13"	"6"	"196"	"23.5"	"11.47"	"3914.61"	"17.37"	"7"	"3"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01280"	"6143"	"ENSG00000108298"	"RPL19"	"B2R4K2; hsa:6143; P14118; P22908; P84098; Q502Y6; Q7Z6E4"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"1"	"577.2"	"929.1"	"1005.4"	"488.4"	"1113.1"	"608.3"	"2351.9"	"1648.4"	"2085.4"	"2450.8"	"3085.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P18669"	"Phosphoglycerate mutase 1 OS=Homo sapiens OX=9606 GN=PGAM1 PE=1 SV=2"	"33"	"5"	"10"	"5"	"254"	"28.8"	"7.18"	"1457.74"	"17.36"	"2"	"5"	"other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;other cell component"	"other molecular function"	"Pf00300"	"5223"	"ENSG00000171314"	"PGAM1"	"hsa:5223; P18669; Q9BWC0"	"Cori cycle; Metabolic reprogramming in colon cancer; Glycolysis and gluconeogenesis"	"Neutrophil degranulation; Glycolysis; Gluconeogenesis"	"6"	"0"	"171.7"	"1495.1"	"1104.1"	"83.1"	"923.3"	"252.9"	"406.1"	"277.1"	"380.1"	"443.6"	"1063.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P00492"	"Hypoxanthine-guanine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=HPRT1 PE=1 SV=2"	"31"	"6"	"11"	"6"	"218"	"24.6"	"6.68"	"1796.92"	"17.29"	"5"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;developmental processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00156"	"3251"	"ENSG00000165704"	"HPRT1"	"A6NHF0; B2R8M9; hsa:3251; P00492"	"Mesodermal commitment pathway"	"Azathioprine ADME; Purine salvage; Defective HPRT1 disrupts guanine and hypoxanthine salvage"	"4"	"0"	"141.5"	"860.1"	"735.9"	"100.5"	"569.1"	"173.5"	"210.9"	"164.4"	"241.7"	"290.5"	"588.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P33992"	"DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5"	"8"	"5"	"12"	"5"	"734"	"82.2"	"8.37"	"1922.42"	"17.26"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf14551, Pf17207, Pf17855"	"4174"	"ENSG00000100297"	"MCM5"	"hsa:4174; O60785; P33992; Q14578; Q9BTJ4; Q9BWL8"	"Cell cycle; Ciliary landscape; G1 to S cell cycle control; DNA replication; 10q11.21q11.23 copy number variation syndrome"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"11"	"0"	"220.0"	"713.3"	"573.5"	"172.4"	"561.9"	"219.2"	"427.0"	"336.9"	"465.8"	"647.4"	"1037.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14558"	"Phosphoribosyl pyrophosphate synthase-associated protein 1 OS=Homo sapiens OX=9606 GN=PRPSAP1 PE=1 SV=2"	"20"	"5"	"13"	"3"	"356"	"39.4"	"7.20"	"2340.44"	"17.25"	"5"	"5"	"other metabolic processes"	"other cell component"	"enzyme regulator activity;other molecular function"	"Pf13793, Pf14572"	"5635"	"ENSG00000161542"	"PRPSAP1"	"B2R6M4; hsa:5635; Q14558; Q96H06"	""	""	"0"	"0"	"58.9"	"99.8"	"93.2"	"49.3"	"120.4"	"57.2"	"69.7"	"76.9"	"102.2"	"163.8"	"222.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15056"	"Eukaryotic translation initiation factor 4H OS=Homo sapiens OX=9606 GN=EIF4H PE=1 SV=5"	"24"	"4"	"9"	"4"	"248"	"27.4"	"7.23"	"1451.00"	"17.18"	"3"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"7458"	"ENSG00000106682"	"EIF4H"	"A8K3R1; D3DXF6; D3DXF8; hsa:7458; Q15056"	"Translation factors; 7q11.23 copy number variation syndrome"	"L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Translation initiation complex formation; Ribosomal scanning and start codon recognition"	"7"	"0"	"192.2"	"823.5"	"658.9"	"170.1"	"621.7"	"204.0"	"345.7"	"253.4"	"355.2"	"430.1"	"724.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09429"	"High mobility group protein B1 OS=Homo sapiens OX=9606 GN=HMGB1 PE=1 SV=3"	"30"	"6"	"12"	"6"	"215"	"24.9"	"5.74"	"2424.63"	"17.11"	"6"	"5"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00505, Pf09011"	"3146"	"ENSG00000189403"	"HMGB1"	"A5D8W9; hsa:3146; P09429; Q14321; Q5T7C3; Q6IBE1"	"Retinoblastoma gene in cancer; VEGFA-VEGFR2 signaling; Supression of HMGB1 mediated inflammation by THBD; Base excision repair; DNA repair pathways, full network; Pleural mesothelioma; Clock-controlled autophagy in bone metabolism; Autophagy in pancreatic ductal adenocarcinoma; DNA damage response (only ATM dependent)"	"ER-Phagosome pathway; Neutrophil degranulation; MyD88 deficiency (TLR2/4); IRAK4 deficiency (TLR2/4); Regulation of TLR by endogenous ligand; Apoptosis induced DNA fragmentation; TAK1-dependent IKK and NF-kappa-B activation  ; TRAF6 mediated NF-kB activation; Pyroptosis; Advanced glycosylation endproduct receptor signaling"	"20"	"0"	"264.9"	"472.7"	"589.5"	"216.7"	"579.0"	"329.0"	"1962.8"	"1502.4"	"2108.3"	"2443.4"	"3884.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50395"	"Rab GDP dissociation inhibitor beta OS=Homo sapiens OX=9606 GN=GDI2 PE=1 SV=2"	"8"	"3"	"8"	"3"	"445"	"50.6"	"6.47"	"1787.71"	"17.06"	"3"	"3"	"transport;signal transduction;other biological processes"	"non-structural extracellular;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00996"	"2665"	"ENSG00000057608"	"GDI2"	"hsa:2665; O43928; P50395; Q5SX88; Q9UQM6"	""	"Neutrophil degranulation; RAB GEFs exchange GTP for GDP on RABs"	"2"	"0"	"130.1"	"880.2"	"684.7"	"103.3"	"602.4"	"192.5"	"202.0"	"165.8"	"239.9"	"303.4"	"636.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NE71"	"ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2"	"7"	"6"	"11"	"6"	"845"	"95.9"	"6.80"	"1993.16"	"17.06"	"5"	"6"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00005, Pf12848"	"23"	"ENSG00000204574; ENSG00000206490; ENSG00000225989; ENSG00000231129; ENSG00000232169; ENSG00000236149; ENSG00000236342"	"ABCF1"	"A2BF75; hsa:23; O14897; Q69YP6; Q8NE71"	"IL-18 signaling pathway"	"ABC-family proteins mediated transport"	"2"	"0"	"313.5"	"484.4"	"621.7"	"286.2"	"660.1"	"363.9"	"936.0"	"634.9"	"939.5"	"1356.8"	"1985.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99714"	"3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3"	"17"	"3"	"7"	"3"	"261"	"26.9"	"7.78"	"946.76"	"17.04"	"2"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"plasma membrane;other membranes;mitochondrion;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00106"	"3028"	"ENSG00000072506"	"HSD17B10"	"hsa:3028; Q5H927; Q6IBS9; Q8TCV9; Q96HD5; Q99714"	"Alzheimer's disease and miRNA effects; Valproic acid pathway; Alzheimer's disease"	"Branched-chain amino acid catabolism; tRNA processing in the mitochondrion; tRNA modification in the mitochondrion; rRNA processing in the mitochondrion"	"7"	"0"	"137.5"	"520.9"	"440.1"	"127.3"	"394.0"	"183.4"	"242.7"	"202.9"	"300.4"	"405.7"	"646.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y265"	"RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1 PE=1 SV=1"	"14"	"6"	"13"	"6"	"456"	"50.2"	"6.42"	"2079.73"	"17.01"	"6"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf06068, Pf17856"	"8607"	"ENSG00000175792; ENSG00000284901"	"RUVBL1"	"B2R5S0; hsa:8607; P82276; Q1KMR0; Q53HK5; Q53HL7; Q53Y27; Q9BSX9; Q9Y265"	"Gastric cancer network 1; lncRNA in canonical Wnt signaling and colorectal cancer"	"Ub-specific processing proteases; Deposition of new CENPA-containing nucleosomes at the centromere; Formation of the beta-catenin:TCF transactivating complex; HATs acetylate histones; DNA Damage Recognition in GG-NER; UCH proteinases; Telomere Extension By Telomerase"	"9"	"0"	"220.6"	"635.4"	"594.6"	"175.7"	"552.2"	"278.7"	"359.6"	"257.9"	"350.8"	"506.8"	"742.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92917"	"G-patch domain and KOW motifs-containing protein OS=Homo sapiens OX=9606 GN=GPKOW PE=1 SV=2"	"11"	"5"	"10"	"5"	"476"	"52.2"	"6.15"	"2008.12"	"17.01"	"5"	"5"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00467, Pf12656"	"27238"	"ENSG00000068394"	"GPKOW"	"hsa:27238; Q59EK5; Q92917; Q9BQA8"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"269.6"	"391.6"	"438.3"	"289.6"	"451.4"	"287.5"	"562.3"	"628.9"	"958.4"	"1394.6"	"2692.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQ61"	"Telomerase RNA component interacting RNase OS=Homo sapiens OX=9606 GN=TRIR PE=1 SV=1"	"15"	"1"	"4"	"1"	"176"	"18.4"	"9.44"	""	"16.96"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	""	"nucleic acid binding activity;other molecular function"	""	"79002"	"ENSG00000123144"	"TRIR"	"hsa:79002; Q9BQ61"	""	""	"0"	"0"	"27.2"	"39.4"	"39.2"	"25.9"	"41.1"	"32.8"	"46.4"	"40.1"	"57.1"	"52.1"	"66.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62847"	"40S ribosomal protein S24 OS=Homo sapiens OX=9606 GN=RPS24 PE=1 SV=1"	"33"	"4"	"9"	"4"	"133"	"15.4"	"10.78"	"1356.59"	"16.88"	"2"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01282"	"6229"	"ENSG00000138326"	"RPS24"	"E7EPK6; hsa:6229; P16632; P62847; Q5T0P7; Q5T0P8; Q7Z3D1"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"317.9"	"494.7"	"566.4"	"272.2"	"541.8"	"338.3"	"757.7"	"557.1"	"808.6"	"952.9"	"1379.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23588"	"Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2"	"10"	"6"	"11"	"6"	"611"	"69.1"	"5.73"	"2124.25"	"16.88"	"5"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus"	"nucleic acid binding activity"	"Pf00076"	"1975"	"ENSG00000063046"	"EIF4B"	"B4DS13; hsa:1975; P23588; Q4G0E3; Q53HQ2; Q6GPH5; Q6IB46; Q8WYK5"	"Translation factors; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Translation inhibitors in chronically activated PDGFRA cells; Perturbations to host-cell autophagy, induced by SARS-CoV-2 proteins; Pleural mesothelioma; Interferon type I signaling pathways"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Deadenylation of mRNA; mTORC1-mediated signalling"	"14"	"0"	"524.9"	"1313.0"	"1268.8"	"417.5"	"1182.6"	"584.0"	"1001.6"	"698.9"	"940.5"	"1099.4"	"1707.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5S9"	"RNA-binding protein 8A OS=Homo sapiens OX=9606 GN=RBM8A PE=1 SV=1"	"17"	"2"	"10"	"2"	"174"	"19.9"	"5.72"	"3501.91"	"16.85"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"9939"	"ENSG00000265241"	"RBM8A"	"B3KQI9; hsa:9939; Q6FHD1; Q6IQ40; Q9GZX8; Q9NZI4; Q9Y5S9"	""	"mRNA Splicing - Major Pathway; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"6"	"0"	"43.9"	"209.9"	"163.6"	"44.8"	"145.2"	"52.2"	"86.5"	"64.6"	"80.1"	"93.2"	"177.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96F85"	"CB1 cannabinoid receptor-interacting protein 1 OS=Homo sapiens OX=9606 GN=CNRIP1 PE=1 SV=1"	"43"	"5"	"6"	"5"	"164"	"18.6"	"7.94"	"678.30"	"16.84"	"2"	"4"	"other biological processes"	"plasma membrane;other membranes;other cell component"	"signal transduction activity or receptor binding"	"Pf15043"	"25927"	"ENSG00000119865"	"CNRIP1"	"B2R4D0; hsa:25927; Q49AN4; Q96F85; Q9UFZ0"	""	""	"0"	"0"	"72.1"	"196.3"	"253.4"	"82.8"	"266.7"	"135.0"	"286.3"	"451.9"	"1184.9"	"1490.7"	"2253.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92820"	"Gamma-glutamyl hydrolase OS=Homo sapiens OX=9606 GN=GGH PE=1 SV=2"	"22"	"6"	"10"	"6"	"318"	"35.9"	"7.11"	"1305.20"	"16.79"	"4"	"6"	"other metabolic processes"	"non-structural extracellular;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf07722"	"8836"	"ENSG00000137563"	"GGH"	"hsa:8836; Q92820"	"Fluoropyrimidine activity"	"Neutrophil degranulation"	"2"	"0"	"150.3"	"311.5"	"312.4"	"142.4"	"351.3"	"183.9"	"374.3"	"565.9"	"897.1"	"1310.4"	"2555.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00425"	"Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2"	"6"	"3"	"10"	"2"	"579"	"63.7"	"8.87"	"1849.71"	"16.77"	"3"	"3"	"protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf00076"	"10643"	"ENSG00000136231"	"IGF2BP3"	"A0A4Z5; hsa:10643; O00425; Q63HM0; Q6MZZ2; Q86VB1"	""	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"	"1"	"0"	"66.8"	"160.8"	"157.0"	"61.0"	"137.6"	"75.3"	"133.8"	"106.2"	"142.6"	"172.1"	"234.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NRV9"	"Heme-binding protein 1 OS=Homo sapiens OX=9606 GN=HEBP1 PE=1 SV=1"	"31"	"4"	"8"	"4"	"189"	"21.1"	"5.80"	"1077.49"	"16.76"	"2"	"4"	"other biological processes"	"non-structural extracellular;other cell component"	"other molecular function"	"Pf04832"	"50865"	"ENSG00000013583"	"HEBP1"	"A8K1G2; hsa:50865; Q9NRV9; Q9Y5Z5"	""	"G alpha (i) signalling events; Formyl peptide receptors bind formyl peptides and many other ligands"	"2"	"0"	"494.1"	"691.3"	"642.5"	"292.8"	"614.7"	"356.9"	"595.0"	"519.5"	"701.6"	"845.4"	"1092.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09972"	"Fructose-bisphosphate aldolase C OS=Homo sapiens OX=9606 GN=ALDOC PE=1 SV=2"	"13"	"7"	"11"	"1"	"364"	"39.4"	"6.87"	"1541.68"	"16.76"	"5"	"6"	"other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00274"	"230"	"ENSG00000109107"	"ALDOC"	"B2R5R3; hsa:230; P09972; Q3SYL3; Q6FH94; Q6P0L5"	"Clear cell renal cell carcinoma pathways; Glycolysis and gluconeogenesis"	"Neutrophil degranulation; Glycolysis; Gluconeogenesis"	"5"	"0"	"17.1"	"32.1"	"27.9"	"18.4"	"30.7"	"15.4"	"26.2"	"26.3"	"28.7"	"31.6"	"58.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6UXN9"	"WD repeat-containing protein 82 OS=Homo sapiens OX=9606 GN=WDR82 PE=1 SV=1"	"16"	"5"	"8"	"5"	"313"	"35.1"	"7.69"	"834.30"	"16.58"	"3"	"5"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00400"	"80335"	"ENSG00000164091"	"WDR82"	"A8K5R5; hsa:80335; Q6UXN9; Q8TEB2"	""	"Formation of WDR5-containing histone-modifying complexes"	"1"	"0"	"566.7"	"786.7"	"823.5"	"476.2"	"821.7"	"503.9"	"936.9"	"743.0"	"943.4"	"1153.9"	"1690.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15511"	"Actin-related protein 2/3 complex subunit 5 OS=Homo sapiens OX=9606 GN=ARPC5 PE=1 SV=3"	"36"	"4"	"8"	"4"	"151"	"16.3"	"5.67"	"1456.89"	"16.54"	"3"	"3"	"cell organization and biogenesis;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf04699"	"10092"	"ENSG00000162704"	"ARPC5"	"A6NEC4; hsa:10092; O15511; Q6PG42"	"Pathogenic Escherichia coli infection; Regulation of actin cytoskeleton"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Neutrophil degranulation; Clathrin-mediated endocytosis; EPHB-mediated forward signaling"	"8"	"0"	"95.6"	"168.1"	"206.9"	"99.5"	"195.4"	"112.6"	"536.1"	"638.2"	"812.4"	"1294.0"	"2989.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15046"	"Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3"	"11"	"7"	"11"	"7"	"597"	"68.0"	"6.35"	"1784.25"	"16.52"	"5"	"6"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00152, Pf01336"	"3735"	"ENSG00000065427"	"KARS1"	"A8MSK1; D3DUK4; hsa:3735; O14946; Q15046; Q96J25; Q9HB23"	""	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation; Mitochondrial tRNA aminoacylation"	"3"	"0"	"279.0"	"604.3"	"651.9"	"246.0"	"607.6"	"342.8"	"708.6"	"548.9"	"838.4"	"1091.2"	"1737.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P21912"	"Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHB PE=1 SV=3"	"21"	"6"	"11"	"6"	"280"	"31.6"	"8.76"	"1448.16"	"16.49"	"5"	"6"	"other metabolic processes"	"plasma membrane;other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf13085, Pf13534"	"6390"	"ENSG00000117118"	"SDHB"	"B2R545; hsa:6390; P21912; Q0QEY7; Q9NQ12"	"Electron transport chain: OXPHOS system in mitochondria; Metabolic reprogramming in colon cancer; Nonalcoholic fatty liver disease; Mitochondrial complex II assembly; TCA cycle (aka Krebs or citric acid cycle)"	"Respiratory electron transport; Citric acid cycle (TCA cycle)"	"7"	"0"	"553.7"	"1100.8"	"1100.7"	"447.0"	"954.5"	"524.1"	"920.3"	"764.3"	"1048.3"	"1142.6"	"1779.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35270"	"Sepiapterin reductase OS=Homo sapiens OX=9606 GN=SPR PE=1 SV=1"	"22"	"5"	"9"	"5"	"261"	"28.0"	"8.05"	"1515.01"	"16.42"	"4"	"5"	"other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf00106"	"6697"	"ENSG00000116096"	"SPR"	"A8K741; D6W5H2; hsa:6697; P35270; Q53GI9; Q9UBB1"	""	"eNOS activation; Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"	"2"	"0"	"325.7"	"493.3"	"615.4"	"268.9"	"579.9"	"426.0"	"590.1"	"389.8"	"530.7"	"614.7"	"691.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62191"	"26S proteasome regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMC1 PE=1 SV=1"	"18"	"7"	"12"	"6"	"440"	"49.2"	"6.21"	"2545.97"	"16.39"	"7"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf16450, Pf17862"	"5700"	"ENSG00000100764"	"PSMC1"	"B4DR63; hsa:5700; P49014; P62191; Q03527; Q6IAW0; Q6NW36; Q96AZ3"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; N-glycan trimming in the ER and Calnexin/Calreticulin cycle"	"64"	"1"	"343.8"	"745.4"	"759.5"	"283.4"	"637.1"	"355.6"	"427.1"	"382.5"	"555.4"	"736.6"	"1193.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P53680"	"AP-2 complex subunit sigma OS=Homo sapiens OX=9606 GN=AP2S1 PE=1 SV=2"	"27"	"4"	"10"	"4"	"142"	"17.0"	"6.18"	"1662.41"	"16.35"	"4"	"3"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01217"	"1175"	"ENSG00000042753"	"AP2S1"	"B2R4Z4; hsa:1175; O75977; P53680; Q6PK67"	"Synaptic vesicle pathway; VEGFA-VEGFR2 signaling; GABA receptor signaling; EGF/EGFR signaling pathway; Fragile X syndrome"	"MHC class II antigen presentation; Recycling pathway of L1; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; LDL clearance; Retrograde neurotrophin signalling; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; VLDLR internalisation and degradation; Potential therapeutics for SARS; Nef Mediated CD4 Down-regulation; Nef Mediated CD8 Down-regulation"	"18"	"0"	"99.8"	"216.6"	"222.2"	"90.7"	"200.4"	"107.6"	"302.7"	"488.0"	"1709.1"	"2802.8"	"3669.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2W1"	"Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2"	"8"	"6"	"10"	"6"	"955"	"108.6"	"10.15"	"1151.81"	"16.26"	"4"	"6"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf15440"	"9967"	"ENSG00000054118"	"THRAP3"	"D3DPS5; hsa:9967; Q5VTK6; Q9Y2W1"	"Interactome of polycomb repressive complex 2 (PRC2)"	"PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation"	"3"	"0"	"135.5"	"299.9"	"279.2"	"121.4"	"287.2"	"159.9"	"412.3"	"330.0"	"423.8"	"498.3"	"724.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6WKZ4"	"Rab11 family-interacting protein 1 OS=Homo sapiens OX=9606 GN=RAB11FIP1 PE=1 SV=3"	"4"	"5"	"12"	"5"	"1283"	"137.1"	"5.43"	"2388.39"	"16.25"	"5"	"4"	"transport;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00168, Pf09457"	"80223"	"ENSG00000156675"	"RAB11FIP1"	"hsa:80223; J3KNP0; Q307T1; Q6AZK4; Q6WKZ2; Q6WKZ4; Q6WKZ6; Q86YV4; Q8TDL1; Q9H642"	""	""	"0"	"0"	"130.3"	"310.4"	"305.5"	"118.3"	"294.0"	"151.6"	"294.8"	"352.7"	"802.7"	"1390.4"	"2313.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P6C2"	"RNA demethylase ALKBH5 OS=Homo sapiens OX=9606 GN=ALKBH5 PE=1 SV=2"	"5"	"2"	"8"	"2"	"394"	"44.2"	"9.09"	"1833.36"	"16.23"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;ER/Golgi;nucleus"	"other molecular function"	"Pf13532"	"54890"	"ENSG00000091542"	"ALKBH5"	"B4DVJ4; D3DXC6; hsa:54890; Q6P6C2; Q9NXD6"	""	"Reversal of alkylation damage by DNA dioxygenases"	"1"	"0"	"48.4"	"65.6"	"73.1"	"40.6"	"60.0"	"47.6"	"139.3"	"95.1"	"138.2"	"113.8"	"140.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5B9"	"FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1"	"7"	"7"	"11"	"7"	"1047"	"119.8"	"5.66"	"1704.75"	"16.20"	"5"	"6"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus"	"other molecular function"	"Pf00557, Pf08512, Pf08644, Pf14826"	"11198"	"ENSG00000092201"	"SUPT16H"	"hsa:11198; Q6GMT8; Q6P2F1; Q6PJM1; Q9NRX0; Q9Y5B9"	""	"TP53 Regulates Transcription of DNA Repair Genes; Regulation of TP53 Activity through Phosphorylation; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events"	"12"	"0"	"156.7"	"247.2"	"278.8"	"129.0"	"305.2"	"176.1"	"772.8"	"587.2"	"877.1"	"1385.9"	"2601.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P56192"	"Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2"	"5"	"4"	"9"	"4"	"900"	"101.1"	"6.16"	"892.49"	"16.15"	"2"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00043, Pf00458, Pf09334, Pf18485, Pf19303"	"4141"	"ENSG00000166986"	"MARS1"	"B3KVK7; hsa:4141; P56192; Q14895; Q53H14; Q96A15; Q96BZ0; Q9NSE0"	""	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"2"	"0"	"152.9"	"525.1"	"523.7"	"122.6"	"413.8"	"201.7"	"288.1"	"225.8"	"340.4"	"441.8"	"743.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15530"	"3-phosphoinositide-dependent protein kinase 1 OS=Homo sapiens OX=9606 GN=PDPK1 PE=1 SV=1"	"9"	"4"	"9"	"4"	"556"	"63.1"	"7.36"	"1427.29"	"16.01"	"3"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069, Pf14593"	"5170"	"ENSG00000140992"	"PDPK1"	"H0Y4Z0; hsa:5170; O15530; Q59EH6; Q6FI20; Q8IV52; Q9BRD5"	"MicroRNAs in cardiomyocyte hypertrophy; Integrin-mediated cell adhesion; Thyroid stimulating hormone (TSH) signaling pathway; Glioblastoma signaling pathways; B cell receptor signaling pathway; Interleukin-11 signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Cardiac hypertrophic response; Focal adhesion; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Leptin-insulin signaling overlap; PPAR signaling pathway; Endometrial cancer; PI3K-Akt signaling pathway; EGF/EGFR signaling pathway; Head and neck squamous cell carcinoma; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; Modulators of TCR signaling and T cell activation; GDNF signaling; Primary ovarian insufficiency; A network map of Macrophage-stimulating protein (MSP) signaling; ErbB signaling pathway; T-cell receptor signaling pathway; Serotonin HTR1 group and FOS pathway"	"Role of LAT2/NTAL/LAB on calcium mobilization; FCERI mediated NF-kB activation; Downstream TCR signaling; CLEC7A (Dectin-1) signaling; Constitutive Signaling by AKT1 E17K in Cancer; PIP3 activates AKT signaling; Regulation of TP53 Degradation; GPVI-mediated activation cascade; CD28 dependent PI3K/Akt signaling; G beta:gamma signalling through PI3Kgamma; RHO GTPases activate PKNs; Activation of AKT2; Integrin signaling; RSK activation; VEGFR2 mediated vascular permeability; VEGFR2 mediated cell proliferation; Estrogen-stimulated signaling through PRKCZ; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways"	"46"	"0"	"58.5"	"143.5"	"157.4"	"93.7"	"302.0"	"552.8"	"748.8"	"199.6"	"150.2"	"257.6"	"363.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13151"	"Heterogeneous nuclear ribonucleoprotein A0 OS=Homo sapiens OX=9606 GN=HNRNPA0 PE=1 SV=1"	"9"	"3"	"14"	"2"	"305"	"30.8"	"9.29"	"2602.51"	"15.99"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"10949"	"ENSG00000177733"	"HNRNPA0"	"hsa:10949; Q13151; Q6IB18"	""	""	"0"	"0"	"266.9"	"507.7"	"478.4"	"232.2"	"443.0"	"272.8"	"712.5"	"565.5"	"758.2"	"815.7"	"1074.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96N67"	"Dedicator of cytokinesis protein 7 OS=Homo sapiens OX=9606 GN=DOCK7 PE=1 SV=4"	"3"	"5"	"10"	"5"	"2140"	"242.4"	"6.80"	"1730.83"	"15.97"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"other cell component"	"enzyme regulator activity;other molecular function"	"Pf06920, Pf11878, Pf14429, Pf20421, Pf20422"	"85440"	"ENSG00000116641"	"DOCK7"	"hsa:85440; Q00M63; Q2PPY7; Q45RE8; Q45RE9; Q5T1B9; Q5T1C0; Q6ZV32; Q8TB82; Q96N67; Q96NG6; Q96NI0; Q9C092"	""	"RAC1 GTPase cycle; CDC42 GTPase cycle; Factors involved in megakaryocyte development and platelet production; MET activates RAP1 and RAC1"	"4"	"0"	"158.9"	"273.5"	"261.0"	"126.9"	"265.3"	"163.9"	"283.5"	"237.0"	"355.6"	"460.1"	"666.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95239"	"Chromosome-associated kinesin KIF4A OS=Homo sapiens OX=9606 GN=KIF4A PE=1 SV=3"	"4"	"5"	"7"	"5"	"1232"	"139.8"	"6.27"	"757.58"	"15.97"	"2"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00225"	"24137"	"ENSG00000090889"	"KIF4A"	"B2R7V5; D3DVU4; hsa:24137; O95239; Q86TN3; Q86XX7; Q9NNY6; Q9NY24; Q9UMW3"	"Retinoblastoma gene in cancer"	"Recycling pathway of L1; COPI-dependent Golgi-to-ER retrograde traffic; MHC class II antigen presentation; Kinesins"	"5"	"0"	"100.0"	"158.1"	"205.3"	"91.1"	"203.6"	"122.6"	"323.5"	"185.9"	"309.9"	"334.4"	"435.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07237"	"Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3"	"11"	"6"	"11"	"6"	"508"	"57.1"	"4.87"	"1557.17"	"15.95"	"5"	"6"	"protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00085, Pf13848"	"5034"	"ENSG00000185624"	"P4HB"	"B2RDQ2; hsa:5034; P07237; P30037; P32079; Q15205; Q6LDE5"	"VEGFA-VEGFR2 signaling; Type I collagen synthesis in the context of osteogenesis imperfecta"	"Hedgehog ligand biogenesis; Collagen biosynthesis and modifying enzymes; Detoxification of Reactive Oxygen Species; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Insulin processing; Interleukin-12 signaling; Interleukin-23 signaling; Chylomicron assembly; VLDL assembly; LDL remodeling"	"13"	"0"	"365.9"	"1415.5"	"1207.4"	"284.1"	"1049.1"	"405.6"	"692.2"	"599.9"	"753.1"	"899.7"	"1588.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P41250"	"Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3"	"11"	"5"	"7"	"5"	"739"	"83.1"	"7.03"	"1161.72"	"15.92"	"3"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"non-structural extracellular;cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00458, Pf00587, Pf03129"	"2617"	"ENSG00000106105"	"GARS1"	"A0A090N8G0; B3KQA2; B4DIA0; hsa:2617; P41250; Q969Y1"	""	"Cytosolic tRNA aminoacylation; Mitochondrial tRNA aminoacylation"	"2"	"0"	"122.7"	"552.6"	"528.4"	"89.7"	"435.6"	"151.2"	"292.2"	"207.7"	"270.8"	"360.9"	"591.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43719"	"HIV Tat-specific factor 1 OS=Homo sapiens OX=9606 GN=HTATSF1 PE=1 SV=1"	"10"	"6"	"14"	"6"	"755"	"85.8"	"4.40"	"3140.53"	"15.91"	"6"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	"Pf00076"	"27336"	"ENSG00000102241"	"HTATSF1"	"D3DWG9; hsa:27336; O43719; Q59G06; Q99730"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"785.8"	"1020.5"	"1227.9"	"628.2"	"1240.3"	"823.3"	"1630.4"	"1036.3"	"1537.1"	"1594.1"	"1786.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15019"	"Septin-2 OS=Homo sapiens OX=9606 GN=SEPTIN2 PE=1 SV=1"	"18"	"6"	"11"	"6"	"361"	"41.5"	"6.60"	"1894.77"	"15.89"	"6"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00735"	"4735"	"ENSG00000168385"	"SEPTIN2"	"B4DGE8; hsa:4735; Q14132; Q15019; Q53QU3; Q8IUK9; Q96CB0"	"2q37 copy number variation syndrome"	"Anchoring of the basal body to the plasma membrane"	"2"	"0"	"246.5"	"520.2"	"595.6"	"236.5"	"545.0"	"308.3"	"1129.8"	"774.5"	"1309.7"	"1652.9"	"2644.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60645"	"Exocyst complex component 3 OS=Homo sapiens OX=9606 GN=EXOC3 PE=1 SV=3"	"8"	"5"	"9"	"5"	"745"	"85.5"	"6.29"	"1382.78"	"15.87"	"3"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf06046"	"11336"	"ENSG00000180104"	"EXOC3"	"hsa:11336; O60645; Q6P2E8; Q8TEN6; Q8WUW0; Q96DI4"	"Ciliary landscape"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"4"	"0"	"71.9"	"144.2"	"134.3"	"62.1"	"150.7"	"90.3"	"134.0"	"110.1"	"255.8"	"512.8"	"688.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30419"	"Glycylpeptide N-tetradecanoyltransferase 1 OS=Homo sapiens OX=9606 GN=NMT1 PE=1 SV=2"	"9"	"4"	"11"	"4"	"496"	"56.8"	"7.80"	"1887.14"	"15.86"	"4"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf01233, Pf02799"	"4836"	"ENSG00000136448"	"NMT1"	"A8K7C1; hsa:4836; P30419; Q9UE09"	""	"Inactivation, recovery and regulation of the phototransduction cascade; Late Phase of HIV Life Cycle; Activation, myristolyation of BID and translocation to mitochondria"	"3"	"0"	"114.9"	"187.1"	"210.2"	"103.7"	"195.6"	"131.0"	"359.2"	"325.2"	"484.0"	"658.5"	"1178.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P57076"	"Cilia- and flagella-associated protein 298 OS=Homo sapiens OX=9606 GN=CFAP298 PE=1 SV=1"	"21"	"4"	"6"	"4"	"290"	"33.2"	"7.44"	"1097.10"	"15.77"	"2"	"4"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	""	"Pf11069"	"56683"	"ENSG00000159079"	"CFAP298"	"hsa:56683; P57076; Q53FH0"	"Ciliopathies"	""	"1"	"0"	"191.1"	"299.8"	"362.0"	"204.9"	"393.8"	"244.8"	"357.4"	"319.3"	"466.4"	"649.5"	"948.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43242"	"26S proteasome non-ATPase regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PSMD3 PE=1 SV=2"	"13"	"5"	"10"	"5"	"534"	"60.9"	"8.44"	"1384.31"	"15.76"	"4"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf01399, Pf08375"	"5709"	"ENSG00000108344"	"PSMD3"	"B3KMW9; B4DT72; hsa:5709; O43242; Q96EI2; Q9BQA4"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"64"	"0"	"213.7"	"580.5"	"524.0"	"202.2"	"456.7"	"263.6"	"319.2"	"233.4"	"345.5"	"544.1"	"737.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKK9"	"ADP-sugar pyrophosphatase OS=Homo sapiens OX=9606 GN=NUDT5 PE=1 SV=1"	"24"	"5"	"11"	"5"	"219"	"24.3"	"4.94"	"2410.41"	"15.72"	"4"	"4"	"cell organization and biogenesis;other metabolic processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00293"	"11164"	"ENSG00000165609"	"NUDT5"	"A8K516; hsa:11164; Q6IAG0; Q9UH49; Q9UKK9"	"10q11.21q11.23 copy number variation syndrome"	"Phosphate bond hydrolysis by NUDT proteins"	"2"	"0"	"445.5"	"804.9"	"966.5"	"394.3"	"903.7"	"503.8"	"625.4"	"435.6"	"648.2"	"778.8"	"1197.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y6G9"	"Cytoplasmic dynein 1 light intermediate chain 1 OS=Homo sapiens OX=9606 GN=DYNC1LI1 PE=1 SV=3"	"13"	"5"	"9"	"5"	"523"	"56.5"	"6.42"	"1848.94"	"15.69"	"5"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf05783"	"51143"	"ENSG00000144635"	"DYNC1LI1"	"A2RRG7; hsa:51143; Q53HC8; Q53HK7; Q9Y6G9"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein"	"Separation of Sister Chromatids; RHO GTPases Activate Formins; HCMV Early Events; Neutrophil degranulation; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Aggrephagy; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"15"	"0"	"211.1"	"373.1"	"434.1"	"183.0"	"373.4"	"232.0"	"415.2"	"283.4"	"450.0"	"541.2"	"824.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62316"	"Small nuclear ribonucleoprotein Sm D2 OS=Homo sapiens OX=9606 GN=SNRPD2 PE=1 SV=1"	"37"	"4"	"8"	"4"	"118"	"13.5"	"9.91"	"1463.05"	"15.52"	"3"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf01423"	"6633"	"ENSG00000125743"	"SNRPD2"	"A8K797; hsa:6633; J3KPM5; P43330; P62316"	"mRNA processing"	"mRNA Splicing - Major Pathway; SARS-CoV-2 modulates host translation machinery; snRNP Assembly; mRNA Splicing - Minor Pathway"	"5"	"0"	"188.1"	"635.5"	"667.4"	"177.2"	"615.8"	"206.1"	"418.7"	"287.4"	"552.3"	"675.0"	"1118.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96A65"	"Exocyst complex component 4 OS=Homo sapiens OX=9606 GN=EXOC4 PE=1 SV=1"	"4"	"4"	"9"	"4"	"974"	"110.4"	"6.49"	"1263.79"	"15.52"	"4"	"4"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf04048"	"60412"	"ENSG00000131558"	"EXOC4"	"E9PED2; hsa:60412; Q541U8; Q96A65; Q9C0G4; Q9H9K0; Q9P102"	"Ciliary landscape"	"Insulin processing; Translocation of SLC2A4 (GLUT4) to the plasma membrane; VxPx cargo-targeting to cilium"	"4"	"0"	"34.3"	"64.8"	"63.6"	"34.2"	"56.0"	"28.9"	"66.7"	"58.2"	"125.6"	"199.9"	"246.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2S6"	"Translation machinery-associated protein 7 OS=Homo sapiens OX=9606 GN=TMA7 PE=1 SV=1"	"36"	"4"	"12"	"3"	"64"	"7.1"	"9.99"	"2413.07"	"15.50"	"4"	"2"	""	""	""	"Pf09072"	"51372"	"ENSG00000232112"	"TMA7"	"hsa:51372; Q9P052; Q9Y2S6"	""	""	"0"	"0"	"555.5"	"489.9"	"632.1"	"430.1"	"589.6"	"459.6"	"2161.7"	"1897.7"	"2077.8"	"2335.2"	"3249.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96I24"	"Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2"	"6"	"4"	"12"	"2"	"572"	"61.6"	"8.38"	"1674.14"	"15.48"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"translational apparatus;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00013"	"8939"	"ENSG00000107164"	"FUBP3"	"A3KFK8; A3KFL0; hsa:8939; Q92946; Q96I24; Q9BVB6"	""	""	"0"	"0"	"49.0"	"283.2"	"219.5"	"29.3"	"156.6"	"54.4"	"101.0"	"60.3"	"105.4"	"132.7"	"285.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P43243"	"Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2"	"7"	"5"	"10"	"5"	"847"	"94.6"	"6.25"	"1704.44"	"15.44"	"5"	"5"	"stress response;developmental processes;other biological processes"	"other membranes;nucleus"	"nucleic acid binding activity;other molecular function"	""	"9782"	"ENSG00000015479"	"MATR3"	"B7ZAV5; D3DQC3; hsa:9782; P43243; Q9UHW0; Q9UQ27"	""	""	"0"	"0"	"264.9"	"546.2"	"580.6"	"232.7"	"582.4"	"296.3"	"388.8"	"266.3"	"413.9"	"453.3"	"702.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00299"	"Chloride intracellular channel protein 1 OS=Homo sapiens OX=9606 GN=CLIC1 PE=1 SV=4"	"24"	"4"	"8"	"4"	"241"	"26.9"	"5.17"	"1613.06"	"15.39"	"4"	"4"	"transport;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;mitochondrion;nucleus;other cell component"	"transporter activity"	"Pf13409, Pf13410"	"1192"	"ENSG00000206394; ENSG00000213719; ENSG00000223639; ENSG00000226248; ENSG00000226417; ENSG00000226651; ENSG00000230685"	"CLIC1"	"hsa:1192; O00299; Q15089; Q502X1"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"86.1"	"388.3"	"339.4"	"62.7"	"334.6"	"118.7"	"163.2"	"116.0"	"190.6"	"273.9"	"461.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NVZ3"	"Adaptin ear-binding coat-associated protein 2 OS=Homo sapiens OX=9606 GN=NECAP2 PE=1 SV=1"	"10"	"2"	"7"	"2"	"263"	"28.3"	"8.38"	"1342.79"	"15.37"	"1"	"2"	"transport"	"plasma membrane;other membranes"	""	"Pf07933"	"55707"	"ENSG00000157191"	"NECAP2"	"B4DY19; E9PGQ8; hsa:55707; Q5VSU4; Q5VSU5; Q9H7L1; Q9H8L1; Q9NVZ3"	""	"Cargo recognition for clathrin-mediated endocytosis"	"2"	"0"	"55.0"	"101.5"	"106.8"	"53.3"	"117.2"	"66.0"	"139.4"	"196.7"	"612.3"	"1058.1"	"1600.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00139"	"Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3"	"7"	"5"	"9"	"5"	"706"	"79.9"	"6.68"	"1375.90"	"15.31"	"4"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225"	"3796"	"ENSG00000068796"	"KIF2A"	"A5YM42; A5YM54; B4DY54; D3DW97; E9PB70; hsa:3796; O00139; Q7Z5I3; Q8N5Q7"	""	"COPI-dependent Golgi-to-ER retrograde traffic; Separation of Sister Chromatids; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Kinesins; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"9"	"0"	"260.5"	"482.6"	"541.8"	"239.0"	"484.8"	"319.2"	"594.7"	"412.6"	"676.4"	"813.6"	"1149.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P15924"	"Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3"	"3"	"8"	"11"	"8"	"2871"	"331.6"	"6.81"	"1615.57"	"15.23"	"6"	"5"	"cell adhesion;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00681, Pf17902, Pf18373"	"1832"	"ENSG00000096696"	"DSP"	"B2RTT2; D7RX09; hsa:1832; O75993; P15924; Q14189; Q9UHN4"	"Arrhythmogenic right ventricular cardiomyopathy; Lung fibrosis; Epithelial to mesenchymal transition in colorectal cancer"	"Neutrophil degranulation; Formation of the cornified envelope; RND3 GTPase cycle; RND1 GTPase cycle; Apoptotic cleavage of cell adhesion  proteins"	"9"	"0"	"138.6"	"335.2"	"1221.9"	"101.7"	"242.0"	"137.9"	"328.4"	"256.4"	"345.6"	"480.4"	"592.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60660"	"Myosin light polypeptide 6 OS=Homo sapiens OX=9606 GN=MYL6 PE=1 SV=2"	"32"	"4"	"10"	"4"	"151"	"16.9"	"4.65"	"1793.32"	"15.12"	"4"	"4"	"other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	""	"4637"	"ENSG00000092841"	"MYL6"	"hsa:4637; P16475; P24572; P24573; P60660; Q12790; Q561V9; Q6IAZ0; Q6IPY5"	"Ciliary landscape"	"RHO GTPases activate CIT; EPHA-mediated growth cone collapse; Sema4D induced cell migration and growth-cone collapse; Smooth Muscle Contraction; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; RHO GTPases activate PAKs"	"8"	"0"	"151.5"	"409.5"	"486.6"	"123.2"	"391.5"	"186.8"	"393.4"	"265.9"	"407.4"	"549.8"	"918.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14258"	"E3 ubiquitin/ISG15 ligase TRIM25 OS=Homo sapiens OX=9606 GN=TRIM25 PE=1 SV=2"	"9"	"5"	"10"	"5"	"630"	"70.9"	"8.09"	"1843.92"	"15.10"	"5"	"5"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00622, Pf13445, Pf13765"	"7706"	"ENSG00000121060"	"TRIM25"	"hsa:7706; Q14258"	"Novel intracellular components of RIG-I-like receptor pathway; Cytosolic DNA-sensing pathway; SARS-CoV-2 innate immunity evasion and cell-specific immune response; 1p36 copy number variation syndrome"	"SARS-CoV-1 activates/modulates innate immune responses; Termination of translesion DNA synthesis; Interferon gamma signaling; ISG15 antiviral mechanism; SARS-CoV-2 activates/modulates innate and adaptive immune responses; TRAF6 mediated NF-kB activation; NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10; Negative regulators of DDX58/IFIH1 signaling; Ovarian tumor domain proteases; TRAF3-dependent IRF activation pathway; TRAF6 mediated IRF7 activation"	"16"	"0"	"207.7"	"434.9"	"444.5"	"186.6"	"439.8"	"239.8"	"464.9"	"317.0"	"514.4"	"706.8"	"1024.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UG63"	"ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2"	"13"	"7"	"12"	"7"	"623"	"71.2"	"7.37"	"1365.35"	"15.08"	"5"	"7"	""	""	"other molecular function"	"Pf00005, Pf12848"	"10061; 114483834"	"ENSG00000033050"	"ABCF2"	"hsa:10061; hsa:114483834; O60864; Q75MJ0; Q75MJ1; Q96TE8; Q9UG63"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"130.0"	"307.6"	"306.9"	"124.6"	"305.5"	"147.3"	"273.1"	"196.3"	"319.9"	"395.6"	"573.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P32322"	"Pyrroline-5-carboxylate reductase 1, mitochondrial OS=Homo sapiens OX=9606 GN=PYCR1 PE=1 SV=2"	"17"	"4"	"10"	"3"	"319"	"33.3"	"7.61"	"1692.81"	"15.07"	"3"	"3"	"other metabolic processes;stress response;other biological processes"	"mitochondrion"	"other molecular function"	"Pf03807, Pf14748"	"5831"	"ENSG00000183010"	"PYCR1"	"A6NFM2; B4DMU0; hsa:5831; P32322; Q6FHI4; Q96DI6; Q9HBQ4"	"Amino acid metabolism; Metabolic reprogramming in colon cancer"	"Glutamate and glutamine metabolism"	"3"	"0"	"289.4"	"368.6"	"448.0"	"208.6"	"410.2"	"268.1"	"584.8"	"401.2"	"581.2"	"645.0"	"901.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P42677"	"40S ribosomal protein S27 OS=Homo sapiens OX=9606 GN=RPS27 PE=1 SV=3"	"38"	"3"	"9"	"3"	"84"	"9.5"	"9.45"	"1163.20"	"15.05"	"3"	"3"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01667"	"6232"	"ENSG00000177954"	"RPS27"	"hsa:6232; P42677; Q5T4L6"	"Cytoplasmic ribosomal proteins; 11p11.2 copy number variation syndrome"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"26"	"0"	"304.9"	"662.8"	"614.0"	"320.5"	"642.1"	"333.4"	"693.0"	"560.6"	"692.4"	"919.4"	"1368.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22033"	"Methylmalonyl-CoA mutase, mitochondrial OS=Homo sapiens OX=9606 GN=MMUT PE=1 SV=4"	"8"	"5"	"10"	"5"	"750"	"83.1"	"6.93"	"1621.75"	"15.05"	"5"	"5"	"other metabolic processes;developmental processes;other biological processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf01642, Pf02310"	"4594"	"ENSG00000146085"	"MMUT"	"A8K953; hsa:4594; P22033; Q5SYZ3; Q96B11; Q9UD64"	"Vitamin B12 metabolism; Amino acid metabolism"	"Propionyl-CoA catabolism; Defective MMAA causes MMA, cblA type; Defective MUT causes MMAM; Cobalamin (Cbl) metabolism"	"6"	"0"	"60.7"	"124.9"	"138.8"	"58.4"	"138.3"	"67.8"	"121.7"	"163.6"	"247.4"	"364.0"	"794.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBN7"	"Histone deacetylase 6 OS=Homo sapiens OX=9606 GN=HDAC6 PE=1 SV=2"	"3"	"4"	"10"	"4"	"1215"	"131.3"	"5.30"	"1670.70"	"15.02"	"4"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00850, Pf02148"	"10013"	"ENSG00000094631"	"HDAC6"	"hsa:10013; O94975; Q6NT75; Q7L3E5; Q96CY0; Q9UBN7"	"Neural crest differentiation; Ectoderm differentiation; Ectoderm differentiation; Ethanol effects on histone modifications; 7q11.23 copy number variation syndrome"	"Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; NOTCH1 Intracellular Domain Regulates Transcription; Cilium Assembly; Aggrephagy; Late endosomal microautophagy; Transcriptional regulation by RUNX2; Notch-HLH transcription pathway; RUNX2 regulates osteoblast differentiation; Chaperone Mediated Autophagy; HSF1 activation"	"16"	"0"	"233.1"	"440.5"	"527.3"	"231.8"	"440.9"	"285.4"	"428.4"	"293.7"	"392.3"	"444.7"	"555.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61224"	"Ras-related protein Rap-1b OS=Homo sapiens OX=9606 GN=RAP1B PE=1 SV=1"	"20"	"4"	"8"	"4"	"184"	"20.8"	"5.78"	"1875.54"	"15.01"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00071"	"5908"	"ENSG00000127314"	"RAP1B"	"B2R5Z2; B4DQI8; B4DW74; B4DW94; hsa:5908; P09526; P61224; Q502X3; Q5TZR4; Q6DCA1; Q6LES0"	"Integrin-mediated cell adhesion; Thyroid stimulating hormone (TSH) signaling pathway; Androgen receptor network in prostate cancer; Corticotropin-releasing hormone signaling pathway; Common pathways underlying drug addiction; Focal adhesion; Hepatocyte growth factor receptor signaling; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Ras signaling"	"Neutrophil degranulation; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Signaling by BRAF and RAF1 fusions; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; Rap1 signalling; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; GRB2:SOS provides linkage to MAPK signaling for Integrins ; p130Cas linkage to MAPK signaling for integrins; MET activates RAP1 and RAC1"	"25"	"0"	"305.0"	"580.0"	"495.2"	"208.1"	"524.9"	"310.1"	"594.6"	"422.9"	"540.0"	"613.0"	"850.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15599"	"Na(+)/H(+) exchange regulatory cofactor NHE-RF2 OS=Homo sapiens OX=9606 GN=SLC9A3R2 PE=1 SV=2"	"11"	"3"	"6"	"3"	"337"	"37.4"	"7.93"	"1439.96"	"15.00"	"3"	"3"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00595, Pf09007"	"9351"	"ENSG00000065054"	"NHERF2"	"D3DU84; D3DU85; H3BSV6; hsa:9351; O00272; O00556; Q15599; Q3KQY7"	""	""	"0"	"0"	"71.4"	"150.7"	"152.4"	"85.1"	"174.5"	"100.6"	"171.1"	"143.7"	"348.9"	"516.7"	"790.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51398"	"28S ribosomal protein S29, mitochondrial OS=Homo sapiens OX=9606 GN=DAP3 PE=1 SV=1"	"11"	"4"	"9"	"4"	"398"	"45.5"	"8.88"	"1360.09"	"14.88"	"4"	"4"	"protein metabolism;other metabolic processes;signal transduction"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf10236"	"7818"	"ENSG00000132676"	"DAP3"	"B4DP59; B4DY62; E7EM60; hsa:7818; P51398; Q13044; Q68CT7; Q96Q20"	"CKAP4 signaling pathway map"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"4"	"0"	"233.0"	"463.9"	"485.1"	"231.9"	"470.1"	"315.4"	"410.6"	"283.0"	"421.7"	"534.4"	"724.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25205"	"DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3"	"9"	"5"	"9"	"5"	"808"	"90.9"	"5.77"	"1886.37"	"14.83"	"5"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf14551, Pf17207, Pf17855"	"4172"	"ENSG00000112118"	"MCM3"	"B4DWW4; hsa:4172; P25205; Q92660; Q9BTR3; Q9NUE7"	"Cell cycle; Retinoblastoma gene in cancer; Ciliary landscape; G1 to S cell cycle control; DNA replication; 10q11.21q11.23 copy number variation syndrome"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"12"	"0"	"77.9"	"238.7"	"222.1"	"61.8"	"203.0"	"85.3"	"153.3"	"121.0"	"171.4"	"280.0"	"415.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16658"	"Fascin OS=Homo sapiens OX=9606 GN=FSCN1 PE=1 SV=3"	"12"	"5"	"9"	"5"	"493"	"54.5"	"7.24"	"1790.82"	"14.75"	"5"	"4"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf06268"	"6624"	"ENSG00000075618"	"FSCN1"	"A6NI89; B2RE97; hsa:6624; Q16658; Q96IC5; Q96IH1; Q9BRF1"	"VEGFA-VEGFR2 signaling; Urotensin-II-mediated signaling pathway"	"Interleukin-4 and Interleukin-13 signaling"	"3"	"0"	"44.9"	"361.6"	"219.7"	"19.5"	"219.9"	"49.8"	"83.2"	"90.9"	"97.2"	"160.3"	"304.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96H20"	"Vacuolar-sorting protein SNF8 OS=Homo sapiens OX=9606 GN=SNF8 PE=1 SV=1"	"10"	"4"	"10"	"4"	"258"	"28.8"	"6.65"	"1602.67"	"14.70"	"4"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf04157"	"11267"	"ENSG00000159210"	"SNF8"	"hsa:11267; Q8IXY3; Q96H20; Q9UN50"	""	"Endosomal Sorting Complex Required For Transport (ESCRT); HCMV Late Events"	"2"	"0"	"145.3"	"206.2"	"246.1"	"130.2"	"275.2"	"188.0"	"690.9"	"1181.2"	"1900.4"	"2573.5"	"4514.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49959"	"Double-strand break repair protein MRE11 OS=Homo sapiens OX=9606 GN=MRE11 PE=1 SV=3"	"9"	"5"	"9"	"5"	"708"	"80.5"	"5.90"	"2001.34"	"14.67"	"5"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00149, Pf04152"	"4361"	"ENSG00000020922"	"MRE11"	"B3KTC7; hsa:4361; O43475; P49959"	"miRNA regulation of DNA damage response; Homologous recombination; DDX1 as a regulatory component of the Drosha microprocessor; ATM signaling in development and disease ; Breast cancer pathway; Joubert syndrome; DNA repair pathways, full network; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; Neurogenesis regulation in the olfactory epithelium; DNA damage response"	"Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Meiotic recombination; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Resolution of D-loop Structures through Holliday Junction Intermediates; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Cytosolic sensors of pathogen-associated DNA ; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; DNA Damage/Telomere Stress Induced Senescence; Nonhomologous End-Joining (NHEJ); HDR through MMEJ (alt-NHEJ); Sensing of DNA Double Strand Breaks; IRF3-mediated induction of type I IFN"	"32"	"0"	"92.4"	"171.9"	"197.2"	"94.3"	"190.3"	"102.0"	"213.4"	"181.8"	"268.8"	"332.8"	"489.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3U8"	"60S ribosomal protein L36 OS=Homo sapiens OX=9606 GN=RPL36 PE=1 SV=3"	"43"	"6"	"16"	"6"	"105"	"12.2"	"11.59"	"3527.89"	"14.67"	"6"	"3"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus"	"other molecular function"	"Pf01158"	"25873"	"ENSG00000130255"	"RPL36"	"B2R4Y1; D6W634; hsa:25873; Q6FIG1; Q9UQF6; Q9Y3U8"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Selenocysteine synthesis; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"702.2"	"1699.3"	"1556.8"	"651.4"	"1471.0"	"696.3"	"2260.9"	"2014.4"	"2384.5"	"3281.4"	"4631.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52907"	"F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3"	"15"	"3"	"7"	"3"	"286"	"32.9"	"5.69"	"1167.44"	"14.62"	"3"	"3"	"cell organization and biogenesis"	"non-structural extracellular;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf01267"	"829"	"ENSG00000116489"	"CAPZA1"	"hsa:829; P52907; Q53FQ6; Q6FHD5"	""	"MHC class II antigen presentation; COPI-mediated anterograde transport; Sensory processing of sound by inner hair cells of the cochlea; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-independent Golgi-to-ER retrograde traffic; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Factors involved in megakaryocyte development and platelet production; Advanced glycosylation endproduct receptor signaling"	"8"	"0"	"79.0"	"124.8"	"148.8"	"73.7"	"144.4"	"87.4"	"125.1"	"102.5"	"152.2"	"158.7"	"232.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P42765"	"3-ketoacyl-CoA thiolase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAA2 PE=1 SV=2"	"10"	"4"	"9"	"4"	"397"	"41.9"	"8.09"	"1226.05"	"14.54"	"3"	"4"	"cell organization and biogenesis;other metabolic processes;stress response;transport"	"mitochondrion"	"other molecular function"	"Pf00108, Pf02803"	"10449"	"ENSG00000167315"	"ACAA2"	"hsa:10449; P42765; Q9BUT6"	"Fatty acid biosynthesis; 10q11.21q11.23 copy number variation syndrome"	"Mitochondrial Fatty Acid Beta-Oxidation"	"3"	"0"	"126.6"	"286.6"	"325.3"	"119.3"	"254.7"	"131.3"	"353.6"	"336.8"	"416.8"	"800.4"	"1800.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95202"	"Mitochondrial proton/calcium exchanger protein OS=Homo sapiens OX=9606 GN=LETM1 PE=1 SV=1"	"6"	"5"	"9"	"5"	"739"	"83.3"	"6.70"	"1465.80"	"14.52"	"5"	"4"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;translation activity;other molecular function"	"Pf07766"	"3954"	"ENSG00000168924"	"LETM1"	"B4DED2; hsa:3954; O95202; Q9UF65"	""	"RHOG GTPase cycle; Mitochondrial calcium ion transport"	"2"	"0"	"349.8"	"823.7"	"823.3"	"270.9"	"770.8"	"350.1"	"577.3"	"436.6"	"585.1"	"778.1"	"1165.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15160"	"DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1"	"11"	"4"	"9"	"4"	"346"	"39.2"	"5.50"	"1298.70"	"14.50"	"3"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01000, Pf01193"	"9533"	"ENSG00000171453"	"POLR1C"	"hsa:9533; O15160; O75395; Q5JTE3"	"Pyrimidine metabolism; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"15"	"0"	"167.7"	"376.7"	"354.2"	"136.5"	"396.9"	"201.3"	"328.6"	"453.0"	"1105.7"	"1768.1"	"2261.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43583"	"Density-regulated protein OS=Homo sapiens OX=9606 GN=DENR PE=1 SV=2"	"19"	"3"	"8"	"3"	"198"	"22.1"	"5.30"	"1585.36"	"14.48"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	""	"nucleic acid binding activity"	"Pf01253"	"8562"	"ENSG00000139726"	"DENR"	"hsa:8562; O43583; Q9H3U6; Q9UKZ0"	""	""	"0"	"0"	"69.9"	"130.6"	"153.3"	"53.7"	"144.8"	"87.9"	"412.6"	"323.0"	"498.3"	"735.1"	"1314.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NPJ3"	"Acyl-coenzyme A thioesterase 13 OS=Homo sapiens OX=9606 GN=ACOT13 PE=1 SV=1"	"18"	"2"	"8"	"2"	"140"	"15.0"	"9.14"	"1497.42"	"14.44"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;mitochondrion"	"other molecular function"	"Pf03061"	"55856"	"ENSG00000112304"	"ACOT13"	"F5H2L4; hsa:55856; O95549; Q9NPJ3"	""	"Mitochondrial Fatty Acid Beta-Oxidation"	"1"	"0"	"67.1"	"94.7"	"124.2"	"56.6"	"101.5"	"77.8"	"160.8"	"129.2"	"216.4"	"287.7"	"583.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P43686"	"26S proteasome regulatory subunit 6B OS=Homo sapiens OX=9606 GN=PSMC4 PE=1 SV=2"	"8"	"2"	"6"	"2"	"418"	"47.3"	"5.21"	"1139.18"	"14.39"	"2"	"2"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf16450, Pf17862"	"5704"	"ENSG00000013275; ENSG00000281221"	"PSMC4"	"hsa:5704; P43686; Q96FV5; Q9UBM3; Q9UEX3"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Ciliary landscape; Alzheimer's disease"	"Neddylation; KEAP1-NFE2L2 pathway; Regulation of RAS by GAPs; Regulation of expression of SLITs and ROBOs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Interleukin-1 signaling; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"64"	"0"	"65.9"	"196.9"	"207.8"	"74.7"	"173.5"	"79.8"	"116.4"	"98.3"	"144.4"	"196.8"	"289.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P54727"	"UV excision repair protein RAD23 homolog B OS=Homo sapiens OX=9606 GN=RAD23B PE=1 SV=1"	"12"	"5"	"9"	"5"	"409"	"43.1"	"4.84"	"1516.89"	"14.30"	"4"	"5"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00240, Pf00627, Pf09280"	"5887"	"ENSG00000119318"	"RAD23B"	"B3KWK8; G5E9P0; hsa:5887; P54727; Q7Z5K8; Q8WUB0"	"Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"Formation of Incision Complex in GG-NER; Josephin domain DUBs; DNA Damage Recognition in GG-NER; N-glycan trimming in the ER and Calnexin/Calreticulin cycle"	"7"	"0"	"757.2"	"1391.2"	"1511.4"	"684.8"	"1524.9"	"921.2"	"841.1"	"667.6"	"990.9"	"1094.3"	"1832.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25787"	"Proteasome subunit alpha type-2 OS=Homo sapiens OX=9606 GN=PSMA2 PE=1 SV=2"	"24"	"4"	"8"	"4"	"234"	"25.9"	"7.43"	"1274.23"	"14.28"	"3"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	""	"Pf00227, Pf10584"	"5683"	"ENSG00000106588"	"PSMA2"	"hsa:5683; P25787; Q6ICS6; Q9BU45"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Antigen processing: Ubiquitination & Proteasome degradation; AUF1 (hnRNP D0) binds and destabilizes mRNA; MAPK6/MAPK4 signaling; Downstream TCR signaling; FCERI mediated NF-kB activation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"63"	"0"	"221.7"	"413.5"	"480.7"	"162.1"	"404.6"	"223.8"	"515.0"	"421.4"	"589.2"	"780.2"	"1320.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P21796"	"Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2"	"14"	"4"	"10"	"4"	"283"	"30.8"	"8.54"	"1715.82"	"14.28"	"4"	"4"	"cell-cell signaling;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;mitochondrion;other cell component"	"transporter activity;other molecular function"	"Pf01459"	"7416"	"ENSG00000213585"	"VDAC1"	"B3KVK4; D3DQ93; hsa:7416; P21796; Q5FVE7; Q9UIQ5; Q9UPL0"	"Alzheimer's disease and miRNA effects; Alzheimer's disease; Arsenic metabolism and reactive oxygen species generation; Cholesterol metabolism; Fatty Acids and Lipoproteins Transport in Hepatocytes"	"Ub-specific processing proteases; Pyruvate metabolism; Mitochondrial protein import; PINK1-PRKN Mediated Mitophagy; Mitochondrial calcium ion transport"	"10"	"0"	"238.7"	"1237.9"	"887.4"	"181.6"	"688.1"	"297.8"	"405.3"	"299.8"	"423.2"	"649.7"	"1170.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06493"	"Cyclin-dependent kinase 1 OS=Homo sapiens OX=9606 GN=CDK1 PE=1 SV=3"	"18"	"5"	"7"	"3"	"297"	"34.1"	"8.40"	"1262.53"	"14.21"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069"	"983"	"ENSG00000170312"	"CDK1"	"A8K7C4; C9J497; hsa:983; O60764; P06493"	"miRNA regulation of DNA damage response; Cell cycle; Microtubule cytoskeleton regulation; Spinal cord injury; Retinoblastoma gene in cancer; ATM signaling pathway; PPAR-alpha pathway; Nuclear receptors meta-pathway; ATM signaling in development and disease ; G1 to S cell cycle control; Cohesin complex - Cornelia de Lange syndrome; Urotensin-II-mediated signaling pathway; DNA damage response"	"Golgi Cisternae Pericentriolar Stack Reorganization; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; MAPK6/MAPK4 signaling; The role of GTSE1 in G2/M progression after G2 checkpoint; Resolution of Sister Chromatid Cohesion; Recruitment of NuMA to mitotic centrosomes; Nuclear Pore Complex (NPC) Disassembly; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Regulation of TP53 Degradation; APC/C:Cdc20 mediated degradation of Cyclin B; Phosphorylation of the APC/C; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Transcriptional regulation by RUNX2; Ovarian tumor domain proteases; MASTL Facilitates Mitotic Progression; E2F-enabled inhibition of pre-replication complex formation; MAPK3 (ERK1) activation; Condensation of Prophase Chromosomes; G1/S-Specific Transcription; Initiation of Nuclear Envelope (NE) Reformation; Condensation of Prometaphase Chromosomes; Activation of NIMA Kinases NEK9, NEK6, NEK7; G2/M DNA replication checkpoint; Depolymerization of the Nuclear Lamina; Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1; Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes; Phosphorylation of Emi1"	"49"	"1"	"194.6"	"580.7"	"494.5"	"136.5"	"387.4"	"197.1"	"574.3"	"537.1"	"714.2"	"891.9"	"1626.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62266"	"40S ribosomal protein S23 OS=Homo sapiens OX=9606 GN=RPS23 PE=1 SV=3"	"17"	"3"	"7"	"3"	"143"	"15.8"	"10.49"	"1204.27"	"14.20"	"2"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00164"	"6228"	"ENSG00000186468"	"RPS23"	"hsa:6228; P39028; P62266; Q6IB08"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"317.9"	"616.5"	"639.5"	"325.8"	"661.5"	"329.1"	"984.6"	"916.5"	"960.2"	"1269.2"	"2072.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P40925"	"Malate dehydrogenase, cytoplasmic OS=Homo sapiens OX=9606 GN=MDH1 PE=1 SV=4"	"21"	"7"	"11"	"7"	"334"	"36.4"	"7.36"	"1894.86"	"14.19"	"6"	"5"	"other metabolic processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00056, Pf02866"	"4190"	"ENSG00000014641"	"MDH1"	"B2R5V5; B4DUN2; B7Z3I7; F5H098; hsa:4190; P40925; Q6I9V0"	"Sterol regulatory element-binding proteins (SREBP) signaling; TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Clear cell renal cell carcinoma pathways; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; TCA cycle in senescence; Glycolysis and gluconeogenesis"	"Gluconeogenesis"	"8"	"0"	"340.0"	"2801.5"	"2181.7"	"146.3"	"2012.1"	"511.0"	"639.8"	"455.7"	"627.8"	"771.7"	"1945.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q3SYG4"	"Protein PTHB1 OS=Homo sapiens OX=9606 GN=BBS9 PE=1 SV=1"	"7"	"4"	"7"	"4"	"887"	"99.2"	"5.55"	"1039.30"	"14.11"	"3"	"4"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	""	"Pf14727, Pf14728"	"27241"	"ENSG00000122507"	"BBS9"	"E9PDC9; hsa:27241; P78514; Q3SYG4; Q7KYS6; Q7KYS7; Q8N570; Q99844; Q99854; Q9Y699; Q9Y6A0"	"Ciliary landscape; Genes related to primary cilium development (based on CRISPR); Joubert syndrome; Ciliopathies; Bardet-Biedl syndrome"	"BBSome-mediated cargo-targeting to cilium"	"6"	"0"	"39.2"	"93.0"	"90.1"	"34.8"	"84.0"	"41.4"	"92.7"	"128.2"	"302.3"	"456.8"	"647.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P59998"	"Actin-related protein 2/3 complex subunit 4 OS=Homo sapiens OX=9606 GN=ARPC4 PE=1 SV=3"	"28"	"5"	"8"	"5"	"168"	"19.7"	"8.43"	"1099.45"	"14.10"	"3"	"5"	"cell organization and biogenesis"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf05856"	"10093"	"ENSG00000241553"	"ARPC4"	"C9JWM7; E7ETI0; F6TTL5; hsa:10093; O15509; P59998; Q6P0W5; Q96QJ3"	"Pathogenic Escherichia coli infection"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Clathrin-mediated endocytosis; EPHB-mediated forward signaling"	"6"	"0"	"94.4"	"181.1"	"212.3"	"90.3"	"188.6"	"96.6"	"380.2"	"448.1"	"647.9"	"1257.1"	"2988.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15691"	"Microtubule-associated protein RP/EB family member 1 OS=Homo sapiens OX=9606 GN=MAPRE1 PE=1 SV=3"	"28"	"4"	"11"	"4"	"268"	"30.0"	"5.14"	"1603.69"	"14.05"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf03271"	"22919"	"ENSG00000101367"	"MAPRE1"	"B2R6I7; E1P5M8; hsa:22919; Q15691; Q3KQS8"	"Microtubule cytoskeleton regulation"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; The role of GTSE1 in G2/M progression after G2 checkpoint; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"15"	"0"	"70.9"	"213.4"	"196.8"	"76.2"	"178.7"	"97.6"	"167.2"	"156.4"	"197.4"	"238.2"	"399.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q02790"	"Peptidyl-prolyl cis-trans isomerase FKBP4 OS=Homo sapiens OX=9606 GN=FKBP4 PE=1 SV=3"	"14"	"6"	"10"	"6"	"459"	"51.8"	"5.43"	"1663.07"	"14.05"	"3"	"4"	"cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00254, Pf00515"	"2288"	"ENSG00000004478"	"FKBP4"	"D3DUQ1; hsa:2288; Q02790; Q9UCP1; Q9UCV7"	"Androgen receptor signaling pathway"	"Estrogen-dependent gene expression; Potential therapeutics for SARS; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Attenuation phase"	"6"	"0"	"204.6"	"942.4"	"820.8"	"114.6"	"713.7"	"247.1"	"272.3"	"198.7"	"308.3"	"418.5"	"751.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7L7X3"	"Serine/threonine-protein kinase TAO1 OS=Homo sapiens OX=9606 GN=TAOK1 PE=1 SV=1"	"4"	"3"	"7"	"2"	"1001"	"116.0"	"7.65"	"1164.60"	"14.01"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;cytoskeletal activity;kinase activity;other molecular function"	"Pf00069"	"57551"	"ENSG00000160551"	"TAOK1"	"A2RUT8; B7ZLV6; hsa:57551; Q7L7X3; Q96L75; Q9H2K7; Q9H7S5; Q9P2I6"	"Microtubule cytoskeleton regulation; MAPK signaling pathway"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"8"	"1"	"73.2"	"150.2"	"151.8"	"79.7"	"153.4"	"92.4"	"219.1"	"207.8"	"310.6"	"451.1"	"664.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P40939"	"Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2"	"7"	"5"	"9"	"5"	"763"	"82.9"	"9.04"	"1286.65"	"14.00"	"4"	"5"	"other metabolic processes;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf00378, Pf00725, Pf02737"	"3030"	"ENSG00000084754"	"HADHA"	"B2R7L4; B4DYP2; hsa:3030; P40939; Q16679; Q53T69; Q53TA2; Q96GT7; Q9UQC5"	"Fatty acid beta-oxidation; Mitochondrial long chain fatty acid beta-oxidation; Valproic acid pathway; Mitochondrial fatty acid oxidation disorders; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Acyl chain remodeling of CL; mitochondrial fatty acid beta-oxidation of unsaturated fatty acids; Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA; Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of myristoyl-CoA to lauroyl-CoA; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA; Beta oxidation of palmitoyl-CoA to myristoyl-CoA"	"13"	"0"	"113.2"	"436.9"	"356.6"	"83.0"	"276.2"	"113.1"	"150.2"	"105.2"	"164.1"	"241.2"	"420.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16836"	"Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=HADH PE=1 SV=3"	"16"	"5"	"9"	"5"	"314"	"34.3"	"8.85"	"1280.34"	"13.99"	"3"	"5"	"other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00725, Pf02737"	"3033"	"ENSG00000138796"	"HADH"	"hsa:3033; J3KQ17; O00324; O00397; O00753; Q16836; Q4W5B4"	"Fatty acid beta-oxidation; Fatty acid biosynthesis; Mitochondrial long chain fatty acid beta-oxidation; Amino acid metabolism; IL-18 signaling pathway; Mitochondrial fatty acid oxidation disorders"	"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA; Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of butanoyl-CoA to acetyl-CoA; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA"	"11"	"0"	"108.7"	"240.6"	"290.7"	"116.4"	"282.1"	"157.0"	"1036.2"	"902.6"	"1042.1"	"1649.7"	"3714.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N684"	"Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1"	"8"	"4"	"8"	"4"	"471"	"52.0"	"8.00"	"1527.57"	"13.98"	"4"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"79869"	"ENSG00000149532"	"CPSF7"	"B3KU04; C9K0Q4; hsa:79869; Q7Z3H9; Q8N684; Q9H025; Q9H9V1"	""	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs; RHOBTB1 GTPase cycle"	"5"	"0"	"89.3"	"207.2"	"176.0"	"70.6"	"184.8"	"87.3"	"242.3"	"240.7"	"404.4"	"577.6"	"763.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08758"	"Annexin A5 OS=Homo sapiens OX=9606 GN=ANXA5 PE=1 SV=2"	"22"	"6"	"11"	"6"	"320"	"35.9"	"5.05"	"1759.54"	"13.96"	"6"	"5"	"stress response;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00191"	"308"	"ENSG00000164111"	"ANXA5"	"D3DNW7; hsa:308; P08758; Q6FHB3; Q6FI16; Q8WV69; Q9UDH9"	"Apoptosis-related network due to altered Notch3 in ovarian cancer; Interactions between LOXL4 and oxidative stress pathway; Prostaglandin synthesis and regulation"	"Platelet degranulation"	"4"	"0"	"114.1"	"1046.5"	"964.1"	"56.2"	"746.4"	"195.2"	"291.2"	"221.6"	"338.9"	"390.2"	"817.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H3K6"	"BolA-like protein 2 OS=Homo sapiens OX=9606 GN=BOLA2 PE=1 SV=1"	"51"	"4"	"7"	"4"	"86"	"10.1"	"6.52"	"1185.19"	"13.94"	"3"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01722"	"552900; 654483"	"ENSG00000169627; ENSG00000183336"	"BOLA2; BOLA2B"	"A1L454; A7YDY3; hsa:552900; hsa:654483; Q9H3K6"	""	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	"1"	"0"	"219.5"	"723.4"	"749.6"	"148.6"	"579.7"	"235.6"	"317.3"	"233.7"	"381.5"	"515.2"	"964.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NV70"	"Exocyst complex component 1 OS=Homo sapiens OX=9606 GN=EXOC1 PE=1 SV=4"	"5"	"5"	"10"	"5"	"894"	"101.9"	"6.61"	"1762.25"	"13.93"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf09763, Pf15277"	"55763"	"ENSG00000090989"	"EXOC1"	"hsa:55763; Q504V4; Q8WUE7; Q96T15; Q9NV70; Q9NZE4"	"Ciliary landscape"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"4"	"0"	"196.1"	"473.6"	"472.6"	"193.2"	"433.3"	"227.2"	"477.1"	"525.3"	"1118.2"	"1926.1"	"2904.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q969Q0"	"60S ribosomal protein L36a-like OS=Homo sapiens OX=9606 GN=RPL36AL PE=1 SV=3"	"36"	"6"	"10"	"1"	"106"	"12.5"	"10.65"	"1138.90"	"13.92"	"4"	"6"	"protein metabolism;other metabolic processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;translational apparatus;nucleus"	"other molecular function"	"Pf00935"	"6166"	"ENSG00000165502"	"RPL36AL"	"hsa:6166; Q3B7A5; Q969Q0"	""	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"13"	"0"	"31.3"	"47.4"	"53.4"	"17.0"	"66.1"	"35.7"	"219.2"	"228.8"	"194.9"	"229.8"	"230.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75521"	"Enoyl-CoA delta isomerase 2, mitochondrial OS=Homo sapiens OX=9606 GN=ECI2 PE=1 SV=4"	"12"	"4"	"5"	"4"	"394"	"43.6"	"9.00"	"356.63"	"13.89"	"1"	"4"	"other metabolic processes"	"cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00378, Pf00887"	"10455"	"ENSG00000198721"	"ECI2"	"hsa:10455; O75521; Q5JYK5; Q5JYK7; Q7L124; Q8N0X0; Q9BUE9; Q9H0T9; Q9NQH1; Q9NYH7; Q9UN55"	""	""	"0"	"0"	"174.9"	"383.6"	"353.8"	"155.9"	"305.2"	"209.4"	"415.7"	"324.3"	"518.1"	"830.3"	"1554.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14174"	"Macrophage migration inhibitory factor OS=Homo sapiens OX=9606 GN=MIF PE=1 SV=4"	"21"	"3"	"10"	"3"	"115"	"12.5"	"7.88"	"1827.90"	"13.84"	"3"	"2"	"cell organization and biogenesis;other metabolic processes;stress response;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01187"	"4282"	"ENSG00000240972; ENSG00000276701"	"MIF"	"A5Z1R8; B2R4S3; hsa:4282; P14174; Q2V4Y5; Q6FHV0"	"Adipogenesis; Spinal cord injury"	"Neutrophil degranulation; Cell surface interactions at the vascular wall; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	"5"	"0"	"195.2"	"1209.6"	"947.4"	"101.0"	"779.5"	"251.2"	"359.6"	"277.5"	"380.1"	"516.6"	"953.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TBX8"	"Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma OS=Homo sapiens OX=9606 GN=PIP4K2C PE=1 SV=3"	"13"	"5"	"7"	"5"	"421"	"47.3"	"6.84"	"717.07"	"13.81"	"2"	"5"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf01504"	"79837"	"ENSG00000166908"	"PIP4K2C"	"B2RDL3; B4DM11; B4DY44; hsa:79837; Q8TBX8; Q9H6N2"	"Regulation of actin cytoskeleton"	"Synthesis of PIPs at the plasma membrane; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; PI5P Regulates TP53 Acetylation; Synthesis of PIPs in the nucleus"	"5"	"0"	"51.5"	"111.7"	"131.7"	"54.7"	"118.7"	"78.3"	"239.2"	"277.8"	"1270.9"	"2541.5"	"4441.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86VP6"	"Cullin-associated NEDD8-dissociated protein 1 OS=Homo sapiens OX=9606 GN=CAND1 PE=1 SV=2"	"3"	"3"	"10"	"3"	"1230"	"136.3"	"5.78"	"1509.69"	"13.74"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf08623"	"55832"	"ENSG00000111530"	"CAND1"	"B2RAU3; hsa:55832; O94918; Q6PIY4; Q86VP6; Q8NDJ4; Q96JZ9; Q96T19; Q9BTC4; Q9H0G2; Q9P0H7; Q9UF85"	"Endoderm differentiation"	"Neutrophil degranulation; Neddylation; Iron uptake and transport"	"4"	"0"	"79.6"	"259.0"	"230.2"	"79.2"	"193.6"	"104.9"	"174.2"	"145.3"	"215.1"	"335.6"	"621.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P34896"	"Serine hydroxymethyltransferase, cytosolic OS=Homo sapiens OX=9606 GN=SHMT1 PE=1 SV=1"	"5"	"2"	"8"	"1"	"483"	"53.0"	"7.71"	"1339.12"	"13.69"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00464"	"6470"	"ENSG00000176974; ENSG00000284320"	"SHMT1"	"B4DPM9; D3DXD0; hsa:6470; P34896; Q96HY0; Q9UMD1; Q9UMD2"	"Glycine metabolism; Folate metabolism; One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways; Clear cell renal cell carcinoma pathways; Male infertility; Neuroinflammation and glutamatergic signaling"	"Metabolism of folate and pterines; Carnitine synthesis"	"9"	"0"	"6.5"	"18.2"	"11.7"	"7.2"	"14.7"	"5.5"	"9.5"	"6.8"	"8.2"	"8.1"	"21.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4K4"	"Mitogen-activated protein kinase kinase kinase kinase 5 OS=Homo sapiens OX=9606 GN=MAP4K5 PE=1 SV=2"	"6"	"4"	"7"	"4"	"846"	"95.0"	"7.83"	"1825.15"	"13.65"	"4"	"3"	"protein metabolism;other metabolic processes;signal transduction"	"plasma membrane;other membranes;cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00780"	"11183"	"ENSG00000012983"	"MAP4K5"	"A0A0A0MQR1; hsa:11183; Q8IYF6; Q9Y4K4"	"Angiopoietin-like protein 8 regulatory pathway; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Insulin signaling"	""	"3"	"0"	"73.3"	"112.5"	"137.7"	"69.7"	"134.9"	"85.1"	"160.0"	"172.1"	"316.2"	"445.6"	"785.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13889"	"General transcription factor IIH subunit 3 OS=Homo sapiens OX=9606 GN=GTF2H3 PE=1 SV=2"	"12"	"3"	"8"	"3"	"308"	"34.4"	"7.02"	"1319.07"	"13.57"	"3"	"3"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf03850"	"2967"	"ENSG00000111358"	"GTF2H3"	"B2R819; B4DNZ6; hsa:2967; Q13889; Q7L0G0; Q96AT7"	"Eukaryotic transcription initiation; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; 11p11.2 copy number variation syndrome"	"NoRC negatively regulates rRNA expression; RNA Polymerase I Promoter Escape; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Dual Incision in GG-NER; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Transcription Termination"	"34"	"0"	"68.5"	"145.5"	"144.6"	"72.0"	"154.6"	"86.8"	"215.2"	"322.2"	"600.7"	"839.1"	"957.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BWS9"	"Chitinase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHID1 PE=1 SV=1"	"7"	"3"	"7"	"3"	"393"	"44.9"	"8.63"	"1045.93"	"13.54"	"2"	"3"	"other metabolic processes;stress response;other biological processes"	"non-structural extracellular;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00704"	"66005"	"ENSG00000177830"	"CHID1"	"B3KWB0; hsa:66005; Q8NBM9; Q96CZ3; Q96S93; Q96SK0; Q9BWS9; Q9BY52"	""	"Platelet degranulation"	"1"	"0"	"79.8"	"134.2"	"165.0"	"80.1"	"201.8"	"114.0"	"557.4"	"464.7"	"667.2"	"1092.9"	"2032.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55036"	"26S proteasome non-ATPase regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMD4 PE=1 SV=1"	"14"	"4"	"7"	"4"	"377"	"40.7"	"4.79"	"1281.24"	"13.51"	"3"	"4"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf02809, Pf13519"	"5710"	"ENSG00000159352"	"PSMD4"	"D3DV16; hsa:5710; P55036; Q5VWC5; Q9NS92"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; VEGFA-VEGFR2 signaling; Alzheimer's disease"	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A; MAPK6/MAPK4 signaling; The role of GTSE1 in G2/M progression after G2 checkpoint; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"64"	"0"	"123.6"	"331.6"	"318.2"	"101.8"	"273.8"	"131.1"	"195.1"	"163.1"	"255.0"	"371.7"	"601.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BUJ2"	"Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2"	"6"	"5"	"9"	"4"	"856"	"95.7"	"6.92"	"1324.76"	"13.45"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00622, Pf02037, Pf13671"	"11100"	"ENSG00000105323"	"HNRNPUL1"	"B3KMW7; hsa:11100; O76022; Q6ZSZ0; Q7L8P4; Q8N6Z4; Q96G37; Q9BUJ2; Q9HAL3; Q9UG75"	""	""	"0"	"0"	"220.5"	"456.9"	"465.5"	"170.7"	"408.9"	"219.3"	"385.3"	"304.8"	"403.8"	"479.0"	"771.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06753"	"Tropomyosin alpha-3 chain OS=Homo sapiens OX=9606 GN=TPM3 PE=1 SV=2"	"21"	"7"	"13"	"2"	"285"	"32.9"	"4.72"	"2167.01"	"13.43"	"7"	"6"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton"	"cytoskeletal activity"	"Pf00261"	"7170"	"ENSG00000143549"	"TPM3"	"D3DV71; hsa:7170; P06753; P12324; Q2QD06; Q5VU58; Q5VU63; Q5VU66; Q5VU71; Q5VU72; Q8TCG3; Q969Q2; Q9NQH8"	"Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4); Striated muscle contraction pathway; VEGFA-VEGFR2 signaling"	"Signaling by ALK fusions and activated point mutants; RHOV GTPase cycle; Smooth Muscle Contraction; Striated Muscle Contraction"	"7"	"5"	"287.8"	"1968.8"	"1694.1"	"196.2"	"1263.8"	"340.1"	"703.3"	"477.8"	"737.8"	"980.8"	"2061.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62891"	"60S ribosomal protein L39 OS=Homo sapiens OX=9606 GN=RPL39 PE=1 SV=2"	"20"	"1"	"8"	"1"	"51"	"6.4"	"12.56"	"1351.22"	"13.40"	"1"	"1"	"protein metabolism;other metabolic processes;stress response"	"non-structural extracellular;cytosol;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00832"	"6170"	"ENSG00000198918"	"RPL39"	"hsa:6170; P02404; P39025; P62891; Q9BYF2"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"106.2"	"175.4"	"205.8"	"94.7"	"211.9"	"105.5"	"276.5"	"176.3"	"277.0"	"293.8"	"490.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06746"	"DNA polymerase beta OS=Homo sapiens OX=9606 GN=POLB PE=1 SV=3"	"15"	"4"	"7"	"4"	"335"	"38.2"	"8.95"	"854.87"	"13.36"	"2"	"3"	"DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf10391, Pf14716, Pf14791, Pf14792"	"5423"	"ENSG00000070501"	"POLB"	"B2RC78; hsa:5423; P06746; Q3KP48; Q6FI34"	"Male infertility; Base excision repair; DNA repair pathways, full network"	"Ub-specific processing proteases; APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway; POLB-Dependent Long Patch Base Excision Repair; PCNA-Dependent Long Patch Base Excision Repair; Abasic sugar-phosphate removal via the single-nucleotide replacement pathway"	"10"	"0"	"62.6"	"111.6"	"125.3"	"49.7"	"118.8"	"67.5"	"172.7"	"150.9"	"339.8"	"865.4"	"2045.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19388"	"DNA-directed RNA polymerases I, II, and III subunit RPABC1 OS=Homo sapiens OX=9606 GN=POLR2E PE=1 SV=4"	"28"	"3"	"5"	"3"	"210"	"24.5"	"5.95"	"819.31"	"13.33"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01191, Pf03871"	"5434"	"ENSG00000099817"	"POLR2E"	"B2R6L4; D6W5Y1; hsa:5434; O43380; P19388; Q6PIH5; Q9BT06"	"Pyrimidine metabolism; Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"mRNA Splicing - Major Pathway; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Transcriptional regulation by small RNAs; B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; RNA Polymerase I Promoter Escape; Inhibition of DNA recombination at telomere; RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; Viral Messenger RNA Synthesis; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Transcription Termination; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM"	"57"	"0"	"32.9"	"102.4"	"109.2"	"27.7"	"95.8"	"45.0"	"101.2"	"122.5"	"231.0"	"337.5"	"517.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y490"	"Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3"	"2"	"5"	"9"	"5"	"2541"	"269.6"	"6.07"	"1082.37"	"13.28"	"4"	"5"	"cell adhesion;cell organization and biogenesis;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00373, Pf01608, Pf08913, Pf09141, Pf16511"	"7094"	"ENSG00000137076"	"TLN1"	"A6NMY0; hsa:7094; Q86YD0; Q9NZQ2; Q9UHH8; Q9UPX3; Q9Y490"	"Integrin-mediated cell adhesion; Primary focal segmental glomerulosclerosis (FSGS); Focal adhesion; TROP2 regulatory signaling"	"Platelet degranulation ; p130Cas linkage to MAPK signaling for integrins; Signaling by BRAF and RAF1 fusions; XBP1(S) activates chaperone genes; SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion; Smooth Muscle Contraction; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; GRB2:SOS provides linkage to MAPK signaling for Integrins"	"18"	"0"	"17.7"	"19.3"	"28.0"	"18.2"	"34.6"	"35.8"	"48.3"	"31.7"	"30.3"	"63.5"	"42.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UII2"	"ATPase inhibitor, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5IF1 PE=1 SV=1"	"25"	"4"	"10"	"4"	"106"	"12.2"	"9.35"	"1680.68"	"13.24"	"4"	"4"	"cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"mitochondrion;other cell component"	"enzyme regulator activity;other molecular function"	"Pf04568"	"93974"	"ENSG00000130770; ENSG00000285390"	"ATP5IF1"	"hsa:93974; Q5JXL8; Q6IAQ7; Q9BSL9; Q9UII2"	"Electron transport chain: OXPHOS system in mitochondria"	""	"1"	"0"	"368.1"	"726.7"	"781.6"	"264.4"	"679.1"	"318.6"	"1695.2"	"1518.1"	"2532.9"	"3674.5"	"5874.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75347"	"Tubulin-specific chaperone A OS=Homo sapiens OX=9606 GN=TBCA PE=1 SV=3"	"19"	"2"	"8"	"2"	"108"	"12.8"	"5.29"	"1573.01"	"13.23"	"2"	"2"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02970"	"6902"	"ENSG00000171530"	"TBCA"	"B4DT30; hsa:6902; O75347"	"VEGFA-VEGFR2 signaling"	"Post-chaperonin tubulin folding pathway"	"2"	"0"	"68.3"	"583.2"	"472.1"	"16.2"	"363.2"	"88.6"	"124.1"	"91.1"	"132.8"	"164.0"	"376.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y617"	"Phosphoserine aminotransferase OS=Homo sapiens OX=9606 GN=PSAT1 PE=1 SV=2"	"15"	"6"	"9"	"6"	"370"	"40.4"	"7.66"	"1096.72"	"13.20"	"4"	"5"	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00266"	"29968"	"ENSG00000135069"	"PSAT1"	"hsa:29968; Q5T7G5; Q5T7G6; Q96AW2; Q9BQ12; Q9Y617"	"Trans-sulfuration, one-carbon metabolism and related pathways; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Male infertility; Neuroinflammation and glutamatergic signaling; Amino acid metabolism in triple-negative breast cancer cells"	"Serine biosynthesis"	"7"	"0"	"115.0"	"948.4"	"739.4"	"93.2"	"667.4"	"179.3"	"269.5"	"195.8"	"348.5"	"396.5"	"816.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P10606"	"Cytochrome c oxidase subunit 5B, mitochondrial OS=Homo sapiens OX=9606 GN=COX5B PE=1 SV=2"	"35"	"5"	"9"	"5"	"129"	"13.7"	"8.81"	"1891.78"	"13.18"	"5"	"4"	"other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf01215"	"1329"	"ENSG00000135940"	"COX5B"	"hsa:1329; P10606; Q53YB7; Q96J18; Q99610"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex IV assembly"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"6"	"0"	"243.6"	"903.1"	"797.3"	"197.3"	"664.2"	"292.2"	"483.4"	"405.6"	"545.1"	"759.5"	"1355.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62318"	"Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1"	"31"	"3"	"9"	"3"	"126"	"13.9"	"10.32"	"1765.73"	"13.15"	"3"	"3"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01423"	"6634"	"ENSG00000100028"	"SNRPD3"	"B4DJP7; B5BU13; hsa:6634; P43331; P62318"	"mRNA processing"	"RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway; SARS-CoV-2 modulates host translation machinery; snRNP Assembly; mRNA Splicing - Minor Pathway; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"8"	"0"	"86.6"	"245.3"	"245.6"	"72.2"	"203.8"	"76.0"	"189.3"	"151.6"	"231.4"	"313.9"	"488.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25788"	"Proteasome subunit alpha type-3 OS=Homo sapiens OX=9606 GN=PSMA3 PE=1 SV=2"	"15"	"4"	"8"	"4"	"255"	"28.4"	"5.33"	"1558.45"	"13.14"	"4"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00227, Pf10584"	"5684"	"ENSG00000100567"	"PSMA3"	"B2RCK6; hsa:5684; P25788; Q86U83; Q8N1D8; Q9BS70"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Cross-presentation of soluble exogenous antigens (endosomes); Regulation of ornithine decarboxylase (ODC); Somitogenesis"	"62"	"0"	"417.5"	"567.1"	"692.9"	"331.2"	"670.1"	"455.0"	"942.4"	"686.1"	"892.2"	"1057.3"	"1752.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P26368"	"Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4"	"11"	"4"	"7"	"4"	"475"	"53.5"	"9.09"	"1100.45"	"13.10"	"3"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"11338"	"ENSG00000063244"	"U2AF2"	"hsa:11338; P26368; Q96HC5"	"mRNA processing"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway"	"5"	"0"	"74.5"	"180.1"	"179.0"	"79.1"	"173.8"	"119.3"	"231.1"	"150.0"	"239.8"	"261.4"	"386.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P29401"	"Transketolase OS=Homo sapiens OX=9606 GN=TKT PE=1 SV=3"	"8"	"4"	"8"	"4"	"623"	"67.8"	"7.66"	"1214.05"	"13.03"	"3"	"3"	"other metabolic processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle"	"other molecular function"	"Pf00456, Pf02779, Pf02780"	"7086"	"ENSG00000163931"	"TKT"	"A8K089; B4DE31; E7EPA7; hsa:7086; P29401; Q8TBA3; Q96HH3"	"Pentose phosphate metabolism; VEGFA-VEGFR2 signaling; Metabolic reprogramming in colon cancer; Thiamine metabolic pathways"	"NFE2L2 regulates pentose phosphate pathway genes; Pentose phosphate pathway; Insulin effects increased synthesis of Xylulose-5-Phosphate"	"7"	"0"	"45.6"	"113.2"	"139.2"	"33.3"	"123.1"	"60.3"	"213.0"	"173.9"	"228.2"	"429.8"	"1008.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61956"	"Small ubiquitin-related modifier 2 OS=Homo sapiens OX=9606 GN=SUMO2 PE=1 SV=3"	"23"	"2"	"6"	"2"	"95"	"10.9"	"5.50"	"1066.32"	"13.01"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf11976"	"6613"	"ENSG00000188612"	"SUMO2"	"B2R4I2; hsa:6613; P55855; P61956; Q32Q42; Q6IPZ6; Q96HK1"	""	"Formation of Incision Complex in GG-NER; SUMOylation of DNA damage response and repair proteins; Processing of DNA double-strand break ends; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; SUMOylation of transcription cofactors; SUMOylation of intracellular receptors; Vitamin D (calciferol) metabolism; SUMOylation of transcription factors; SUMO is conjugated to E1 (UBA2:SAE1); SUMO is transferred from E1 to E2 (UBE2I, UBC9); SUMO is proteolytically processed"	"14"	"0"	"89.9"	"571.8"	"478.6"	"74.2"	"419.8"	"129.1"	"180.3"	"131.4"	"205.4"	"398.2"	"1082.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y6W5"	"Wiskott-Aldrich syndrome protein family member 2 OS=Homo sapiens OX=9606 GN=WASF2 PE=1 SV=3"	"3"	"2"	"7"	"2"	"498"	"54.3"	"5.53"	"1465.96"	"12.99"	"2"	"2"	"cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02205"	"10163"	"ENSG00000158195"	"WASF2"	"B4DZN0; hsa:10163; O60794; Q9UDY7; Q9Y6W5"	"Regulation of actin cytoskeleton"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RAC1 GTPase cycle; RHO GTPases Activate WASPs and WAVEs; VEGFA-VEGFR2 Pathway; RAC2 GTPase cycle; RAC3 GTPase cycle"	"8"	"0"	"14.7"	"30.3"	"32.4"	"14.5"	"23.0"	"12.3"	"51.5"	"38.3"	"63.7"	"108.2"	"161.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P67775"	"Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform OS=Homo sapiens OX=9606 GN=PPP2CA PE=1 SV=1"	"16"	"3"	"5"	"3"	"309"	"35.6"	"5.54"	"670.20"	"12.89"	"2"	"3"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00149"	"5515"	"ENSG00000113575"	"PPP2CA"	"hsa:5515; P05323; P13197; P67775"	"Sphingolipid pathway; TNF-alpha signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Dopamine metabolism; Mesodermal commitment pathway; Mesodermal commitment pathway; Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Wnt signaling pathway and pluripotency; PI3K-Akt signaling pathway; Cancer immunotherapy by CTLA4 blockade; FGFR3 signaling in chondrocyte proliferation and terminal differentiation; 16p11.2 proximal deletion syndrome; Glycogen synthesis and degradation; Cohesin complex - Cornelia de Lange syndrome"	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; CTLA4 inhibitory signaling; Separation of Sister Chromatids; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Regulation of TP53 Degradation; Cyclin D associated events in G1; Disassembly of the destruction complex and recruitment of AXIN to the membrane; RAF activation; Cyclin A/B1/B2 associated events during G2/M transition; Beta-catenin phosphorylation cascade; Signaling by GSK3beta mutants; CTNNB1 S33 mutants aren't phosphorylated; CTNNB1 S37 mutants aren't phosphorylated; CTNNB1 S45 mutants aren't phosphorylated; CTNNB1 T41 mutants aren't phosphorylated; APC truncation mutants have impaired AXIN binding; AXIN missense mutants destabilize the destruction complex; Truncations of AMER1 destabilize the destruction complex; Spry regulation of FGF signaling; MASTL Facilitates Mitotic Progression; Regulation of glycolysis by fructose 2,6-bisphosphate metabolism; Initiation of Nuclear Envelope (NE) Reformation; Negative regulation of MAPK pathway; Platelet sensitization by LDL; Inhibition of replication initiation of damaged DNA by RB1/E2F1; DARPP-32 events; PP2A-mediated dephosphorylation of key metabolic factors; ERKs are inactivated"	"52"	"0"	"79.0"	"154.8"	"148.4"	"63.3"	"130.9"	"80.5"	"122.5"	"104.7"	"149.2"	"192.1"	"294.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31040"	"Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHA PE=1 SV=2"	"7"	"5"	"9"	"5"	"664"	"72.6"	"7.39"	"1262.17"	"12.87"	"4"	"5"	"other metabolic processes;developmental processes"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf00890, Pf02910"	"6389"	"ENSG00000073578"	"SDHA"	"A8K5J6; B4DJ60; E9PBJ5; hsa:6389; P31040; Q16395; Q59GW8; Q8IW48; Q9UMY5"	"Electron transport chain: OXPHOS system in mitochondria; TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Nonalcoholic fatty liver disease; Mitochondrial complex II assembly; Arsenic metabolism and reactive oxygen species generation; TCA cycle (aka Krebs or citric acid cycle)"	"Respiratory electron transport; Citric acid cycle (TCA cycle)"	"9"	"0"	"503.7"	"1006.6"	"1028.3"	"390.0"	"943.0"	"492.6"	"820.1"	"682.7"	"896.3"	"1009.7"	"1526.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKY7"	"Protein CDV3 homolog OS=Homo sapiens OX=9606 GN=CDV3 PE=1 SV=1"	"11"	"2"	"6"	"2"	"258"	"27.3"	"6.40"	"1846.75"	"12.86"	"2"	"2"	""	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf15359"	"55573"	"ENSG00000091527"	"CDV3"	"B3KUC2; hsa:55573; Q96IP9; Q9UKY7"	""	""	"0"	"0"	"86.4"	"414.3"	"342.2"	"89.0"	"300.4"	"131.6"	"189.7"	"137.9"	"207.0"	"256.7"	"492.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y295"	"Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1"	"16"	"5"	"9"	"5"	"367"	"40.5"	"8.90"	"1270.13"	"12.85"	"4"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01926, Pf02824, Pf16897"	"4733"	"ENSG00000185721"	"DRG1"	"B2RDS8; hsa:4733; Q6FGP8; Q8WW69; Q9UGF2; Q9Y295"	""	""	"0"	"0"	"133.7"	"307.4"	"315.8"	"128.5"	"282.2"	"168.0"	"331.2"	"275.4"	"390.6"	"514.8"	"724.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30405"	"Peptidyl-prolyl cis-trans isomerase F, mitochondrial OS=Homo sapiens OX=9606 GN=PPIF PE=1 SV=1"	"22"	"6"	"14"	"5"	"207"	"22.0"	"9.38"	"2384.68"	"12.77"	"5"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"other membranes;mitochondrion;other cell component"	"other molecular function"	"Pf00160"	"10105"	"ENSG00000108179"	"PPIF"	"hsa:10105; P30405; Q2YDB7; Q5W131"	"Alzheimer's disease and miRNA effects; Alzheimer's disease"	""	"2"	"1"	"607.1"	"1290.9"	"1622.6"	"558.7"	"1249.8"	"703.6"	"1257.8"	"919.6"	"1309.9"	"1730.8"	"3288.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H2U1"	"ATP-dependent DNA/RNA helicase DHX36 OS=Homo sapiens OX=9606 GN=DHX36 PE=1 SV=2"	"6"	"5"	"8"	"4"	"1008"	"114.7"	"7.68"	"1296.20"	"12.73"	"4"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"170506"	"ENSG00000174953"	"DHX36"	"B2RB00; hsa:170506; Q70JU3; Q8IYE5; Q9H2U1; Q9P240"	"VEGFA-VEGFR2 signaling"	"DEx/H-box helicases activate type I IFN and inflammatory cytokines production"	"2"	"1"	"189.4"	"288.9"	"316.3"	"163.1"	"325.0"	"178.9"	"424.2"	"325.4"	"466.1"	"695.2"	"1040.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y262"	"Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1"	"10"	"5"	"7"	"5"	"564"	"66.7"	"6.34"	"1043.77"	"12.73"	"3"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity"	"Pf10255"	"51386"	"ENSG00000100129"	"EIF3L"	"B2RDG6; B4DYB2; G8JLH4; hsa:51386; Q53HQ1; Q53HT4; Q5QTR1; Q5TI15; Q6ICD2; Q9Y262"	""	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition"	"6"	"0"	"197.3"	"416.6"	"413.0"	"201.4"	"431.4"	"283.0"	"352.2"	"279.1"	"402.3"	"549.5"	"758.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P16403"	"Histone H1.2 OS=Homo sapiens OX=9606 GN=H1-2 PE=1 SV=2"	"31"	"7"	"12"	"2"	"213"	"21.4"	"10.93"	"2755.48"	"12.73"	"7"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00538"	"3006"	"ENSG00000187837"	"H1-2"	"A8K4I2; hsa:3006; P16403"	""	"Apoptosis induced DNA fragmentation; Formation of Senescence-Associated Heterochromatin Foci (SAHF)"	"2"	"4"	"332.4"	"771.3"	"684.3"	"283.5"	"643.7"	"348.9"	"1076.6"	"1064.8"	"1223.2"	"1435.9"	"2140.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P10412"	"Histone H1.4 OS=Homo sapiens OX=9606 GN=H1-4 PE=1 SV=2"	"26"	"6"	"11"	"1"	"219"	"21.9"	"11.03"	"2460.97"	"12.73"	"6"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00538"	"3008"	"ENSG00000168298"	"H1-4"	"hsa:3008; P10412; Q4VB25"	"Pathways affected in adenoid cystic carcinoma"	"Apoptosis induced DNA fragmentation; Formation of Senescence-Associated Heterochromatin Foci (SAHF)"	"3"	"0"	"67.3"	"105.5"	"126.2"	"52.0"	"128.0"	"77.1"	"227.9"	"159.5"	"228.8"	"255.3"	"407.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P16402"	"Histone H1.3 OS=Homo sapiens OX=9606 GN=H1-3 PE=1 SV=2"	"26"	"6"	"11"	"1"	"221"	"22.3"	"11.02"	"2441.29"	"12.73"	"6"	"3"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00538"	"3007"	"ENSG00000124575"	"H1-3"	"B2R751; hsa:3007; P16402; Q2M2I2"	""	"Formation of Senescence-Associated Heterochromatin Foci (SAHF); Apoptosis induced DNA fragmentation"	"2"	"0"	"21.6"	"29.4"	"29.3"	"14.0"	"37.0"	"21.0"	"50.9"	"54.0"	"69.5"	"61.7"	"105.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00232"	"26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3"	"9"	"4"	"10"	"4"	"456"	"52.9"	"7.65"	"1544.13"	"12.65"	"4"	"4"	"protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	""	"Pf01399, Pf18098"	"5718"	"ENSG00000197170"	"PSMD12"	"A6NP15; hsa:5718; O00232; Q53HA2; Q6P053"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Ciliary landscape; Alzheimer's disease"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"65"	"0"	"208.3"	"542.0"	"460.0"	"194.2"	"427.6"	"233.5"	"222.8"	"182.9"	"219.6"	"341.8"	"523.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UJ83"	"2-hydroxyacyl-CoA lyase 1 OS=Homo sapiens OX=9606 GN=HACL1 PE=1 SV=2"	"8"	"4"	"7"	"4"	"578"	"63.7"	"7.36"	"1195.37"	"12.56"	"3"	"4"	"cell organization and biogenesis;other metabolic processes;transport"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00205, Pf02775, Pf02776"	"26061"	"ENSG00000131373"	"HACL1"	"B4DWI1; B4DXI5; E9PEN4; hsa:26061; Q9BV42; Q9P0A2; Q9UJ83"	""	"Peroxisomal protein import; Alpha-oxidation of phytanate"	"2"	"0"	"72.8"	"154.9"	"179.8"	"72.2"	"174.8"	"86.1"	"285.6"	"220.4"	"289.6"	"451.7"	"860.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y314"	"Nitric oxide synthase-interacting protein OS=Homo sapiens OX=9606 GN=NOSIP PE=1 SV=1"	"16"	"3"	"5"	"3"	"301"	"33.2"	"8.82"	"811.66"	"12.54"	"2"	"3"	"other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf15906"	"51070"	"ENSG00000142546"	"NOSIP"	"hsa:51070; Q96FD2; Q9Y314"	""	"NOSIP mediated eNOS trafficking"	"1"	"0"	"46.3"	"98.6"	"97.0"	"47.5"	"90.3"	"50.6"	"121.5"	"119.9"	"202.1"	"348.9"	"644.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86VM9"	"Zinc finger CCCH domain-containing protein 18 OS=Homo sapiens OX=9606 GN=ZC3H18 PE=1 SV=2"	"4"	"4"	"9"	"4"	"953"	"106.3"	"8.32"	"1548.71"	"12.53"	"4"	"3"	"other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf18044"	"124245"	"ENSG00000158545"	"ZC3H18"	"hsa:124245; Q86VM9; Q96DG4; Q96MP7"	""	""	"0"	"0"	"55.4"	"81.9"	"115.2"	"52.2"	"93.7"	"60.2"	"1057.1"	"792.8"	"966.8"	"1014.8"	"1330.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q709F0"	"Acyl-CoA dehydrogenase family member 11 OS=Homo sapiens OX=9606 GN=ACAD11 PE=1 SV=3"	"7"	"5"	"9"	"5"	"780"	"87.2"	"8.02"	"1584.12"	"12.53"	"5"	"4"	"other metabolic processes"	"other membranes;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00441, Pf01636, Pf02770, Pf02771"	"84129"	"ENSG00000240303"	"ACAD11"	"hsa:84129; Q08AF0; Q658N9; Q658Y2; Q6ZND2; Q709F0; Q8WUT6; Q9H9R3"	"p53 transcriptional gene network"	"Mitochondrial Fatty Acid Beta-Oxidation"	"2"	"0"	"165.9"	"376.7"	"417.2"	"164.5"	"347.7"	"173.8"	"412.3"	"433.0"	"826.6"	"1463.4"	"2282.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35998"	"26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3"	"18"	"7"	"12"	"7"	"433"	"48.6"	"5.95"	"2648.65"	"12.52"	"7"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf17862"	"5701"	"ENSG00000161057"	"PSMC2"	"A4D0Q1; B7Z5E2; hsa:5701; P35998; Q3LIA5; Q9UDI3"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"Neutrophil degranulation; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Separation of Sister Chromatids; ABC-family proteins mediated transport; Defective CFTR causes cystic fibrosis; UCH proteinases; Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of expression of SLITs and ROBOs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; MAPK6/MAPK4 signaling; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"64"	"0"	"156.9"	"419.5"	"380.9"	"150.8"	"326.2"	"161.9"	"253.4"	"246.0"	"299.5"	"382.5"	"579.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31942"	"Heterogeneous nuclear ribonucleoprotein H3 OS=Homo sapiens OX=9606 GN=HNRNPH3 PE=1 SV=2"	"12"	"3"	"8"	"3"	"346"	"36.9"	"6.87"	"1419.58"	"12.52"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf00076"	"3189"	"ENSG00000096746"	"HNRNPH3"	"A8K682; B3KRE1; hsa:3189; P31942; Q9BSX1; Q9NP53; Q9NP96; Q9NPA7; Q9NPI4; Q9UFU4; Q9Y4J5"	""	""	"0"	"0"	"24.1"	"89.9"	"82.9"	"36.3"	"101.0"	"48.1"	"65.3"	"60.6"	"89.7"	"134.5"	"195.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55010"	"Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2"	"13"	"6"	"10"	"6"	"431"	"49.2"	"5.58"	"1714.88"	"12.47"	"5"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf01873, Pf02020"	"1983"	"ENSG00000100664"	"EIF5"	"hsa:1983; P55010; Q53XB3; Q9H5N2; Q9UG48"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"4"	"0"	"173.2"	"311.1"	"385.7"	"165.4"	"367.5"	"221.9"	"910.2"	"701.8"	"965.4"	"1294.2"	"2230.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P20618"	"Proteasome subunit beta type-1 OS=Homo sapiens OX=9606 GN=PSMB1 PE=1 SV=2"	"14"	"2"	"6"	"2"	"241"	"26.5"	"8.13"	"1155.28"	"12.47"	"2"	"2"	"protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	""	"Pf00227"	"5689"	"ENSG00000008018"	"PSMB1"	"B5BU76; hsa:5689; P20618; Q9BWA8"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Neutrophil degranulation; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; MAPK6/MAPK4 signaling; The role of GTSE1 in G2/M progression after G2 checkpoint; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"63"	"0"	"95.9"	"163.0"	"167.8"	"78.7"	"169.3"	"117.4"	"217.6"	"166.3"	"215.6"	"264.5"	"435.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BTE3"	"Mini-chromosome maintenance complex-binding protein OS=Homo sapiens OX=9606 GN=MCMBP PE=1 SV=2"	"6"	"3"	"8"	"3"	"642"	"72.9"	"5.87"	"1531.89"	"12.45"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf09739"	"79892"	"ENSG00000197771"	"MCMBP"	"B3KSP7; hsa:79892; Q6IA56; Q9BTE3; Q9BVT9; Q9H916"	""	""	"0"	"0"	"255.6"	"348.1"	"338.0"	"175.8"	"315.1"	"205.1"	"272.0"	"237.7"	"304.9"	"320.8"	"437.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15293"	"Reticulocalbin-1 OS=Homo sapiens OX=9606 GN=RCN1 PE=1 SV=1"	"11"	"3"	"8"	"3"	"331"	"38.9"	"5.00"	"1695.20"	"12.40"	"3"	"3"	"developmental processes"	"ER/Golgi"	"other molecular function"	"Pf13202"	"5954"	"ENSG00000049449"	"RCN1"	"B7Z1M1; D3DR00; hsa:5954; Q15293"	"VEGFA-VEGFR2 signaling"	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation"	"3"	"0"	"171.2"	"403.8"	"453.3"	"136.1"	"368.3"	"165.9"	"231.0"	"201.2"	"317.3"	"394.8"	"688.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55060"	"Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3"	"5"	"5"	"9"	"5"	"971"	"110.3"	"5.77"	"1797.45"	"12.35"	"5"	"4"	"transport"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf03378, Pf03810, Pf08506"	"1434"	"ENSG00000124207"	"CSE1L"	"A3RLL6; B2R5T4; E1P5Y0; F8W904; hsa:1434; O75432; P55060; Q32M40; Q9H5B7; Q9NTS0; Q9UP98; Q9UP99; Q9UPA0"	""	""	"0"	"0"	"144.8"	"533.2"	"433.3"	"112.6"	"404.7"	"150.0"	"198.5"	"183.5"	"232.5"	"326.6"	"561.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P1N0"	"Coiled-coil and C2 domain-containing protein 1A OS=Homo sapiens OX=9606 GN=CC2D1A PE=1 SV=1"	"6"	"4"	"6"	"4"	"951"	"104.0"	"8.09"	"888.70"	"12.29"	"2"	"4"	"RNA metabolism OR transcription;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00168"	"54862"	"ENSG00000132024; ENSG00000288293"	"CC2D1A"	"hsa:54862; Q6P1N0; Q7Z435; Q86XV0; Q8NF89; Q9H603; Q9NXI1"	"Sudden infant death syndrome (SIDS) susceptibility pathways"	""	"1"	"0"	"73.7"	"135.1"	"121.8"	"68.0"	"151.4"	"83.4"	"154.4"	"119.2"	"169.1"	"228.4"	"270.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92616"	"eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6"	"2"	"4"	"9"	"4"	"2671"	"292.6"	"7.47"	"1574.49"	"12.26"	"4"	"3"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"88.1"	"310.9"	"240.5"	"80.9"	"216.8"	"106.8"	"157.0"	"105.7"	"176.2"	"238.1"	"404.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EK6"	"Glucosamine 6-phosphate N-acetyltransferase OS=Homo sapiens OX=9606 GN=GNPNAT1 PE=1 SV=1"	"22"	"3"	"9"	"3"	"184"	"20.7"	"7.99"	"1575.86"	"12.17"	"3"	"3"	"other metabolic processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle"	"other molecular function"	"Pf00583"	"64841"	"ENSG00000100522"	"GNPNAT1"	"hsa:64841; Q96EK6"	""	"Synthesis of UDP-N-acetyl-glucosamine"	"1"	"0"	"30.6"	"92.3"	"115.9"	"33.4"	"97.3"	"39.3"	"82.1"	"71.2"	"105.4"	"120.4"	"211.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P01116"	"GTPase KRas OS=Homo sapiens OX=9606 GN=KRAS PE=1 SV=1"	"27"	"4"	"8"	"4"	"189"	"21.6"	"6.77"	"1533.40"	"12.15"	"4"	"4"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00071"	"3845"	"ENSG00000133703"	"KRAS"	"A8K8Z5; B0LPF9; hsa:3845; P01116; P01118; Q96D10"	"IL-5 signaling pathway; Alzheimer's disease and miRNA effects; Glioblastoma signaling pathways; RalA downstream regulated genes; TNF-alpha signaling pathway; Oncostatin M signaling pathway; Aryl hydrocarbon receptor pathway; Bladder cancer; Extracellular vesicle-mediated signaling in recipient cells; RAC1/PAK1/p38/MMP2 pathway; G protein signaling pathways; BDNF-TrkB signaling; MAPK signaling pathway; PI3K-AKT-mTOR signaling pathway and therapeutic opportunities; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Endometrial cancer; PI3K-Akt signaling pathway; Chromosomal and microsatellite instability in colorectal cancer ; MAPK cascade; Ras signaling; Epithelial to mesenchymal transition in colorectal cancer; Non-small cell lung cancer; Breast cancer pathway; Pancreatic adenocarcinoma pathway; Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells; Thermogenesis; Non-genomic actions of 1,25 dihydroxyvitamin D3; EGF/EGFR signaling pathway; Relationship between inflammation, COX-2 and EGFR; Envelope proteins and their potential roles in EDMD physiopathology; Synaptic signaling pathways associated with autism spectrum disorder; Hippo-Merlin signaling dysregulation; Fragile X syndrome; Gastrin signaling pathway; Hepatitis B infection; Head and neck squamous cell carcinoma; Melanoma; EGFR tyrosine kinase inhibitor resistance; Kisspeptin/kisspeptin receptor system in the ovary; MAPK pathway in congenital thyroid cancer; Regulation of actin cytoskeleton; Alzheimer's disease; Autophagy in pancreatic ductal adenocarcinoma; JAK-STAT signaling in the regulation of Beta-cells; ErbB signaling pathway; DNA damage response (only ATM dependent); Serotonin receptor 2 and ELK-SRF/GATA4 signaling"	"Signaling by CSF3 (G-CSF); Signaling by CSF1 (M-CSF) in myeloid cells; RAS processing; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAS GAP mutants; Signaling by RAS GTPase mutants; RUNX3 regulates p14-ARF"	"57"	"0"	"158.6"	"267.2"	"247.6"	"126.7"	"264.3"	"161.4"	"276.7"	"217.9"	"368.7"	"457.8"	"717.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P40222"	"Alpha-taxilin OS=Homo sapiens OX=9606 GN=TXLNA PE=1 SV=3"	"12"	"4"	"7"	"4"	"546"	"61.9"	"6.52"	"1423.75"	"12.15"	"3"	"4"	"transport;other biological processes"	"non-structural extracellular;cytosol;other cell component"	"other molecular function"	"Pf09728"	"200081"	"ENSG00000084652"	"TXLNA"	"D3DPP6; hsa:200081; P40222; Q5TFJ6; Q66K62; Q86T54; Q86T85; Q86T86; Q86Y86; Q86YW3; Q8N2Y3"	""	"Other interleukin signaling"	"1"	"0"	"64.2"	"138.4"	"157.7"	"63.9"	"157.7"	"72.3"	"246.1"	"230.5"	"362.7"	"699.6"	"1001.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15058"	"Kinesin-like protein KIF14 OS=Homo sapiens OX=9606 GN=KIF14 PE=1 SV=1"	"2"	"4"	"10"	"4"	"1648"	"186.4"	"7.91"	"1491.55"	"12.14"	"4"	"4"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225, Pf00498, Pf16183"	"9928"	"ENSG00000118193"	"KIF14"	"hsa:9928; Q14CI8; Q15058; Q4G0A5; Q5T1W3"	""	"RND2 GTPase cycle; RND1 GTPase cycle; RHO GTPases activate CIT"	"3"	"0"	"187.0"	"374.1"	"403.2"	"176.5"	"398.9"	"217.4"	"438.2"	"579.0"	"1406.2"	"2295.2"	"3249.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09211"	"Glutathione S-transferase P OS=Homo sapiens OX=9606 GN=GSTP1 PE=1 SV=2"	"27"	"4"	"8"	"4"	"210"	"23.3"	"5.64"	"1660.73"	"12.14"	"4"	"2"	"cell cycle OR cell proliferation;other metabolic processes;stress response;developmental processes;other biological processes"	"non-structural extracellular;cytosol;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02798, Pf14497"	"2950"	"ENSG00000084207"	"GSTP1"	"hsa:2950; O00460; P09211; Q15690; Q5TZY3"	"Nuclear receptors meta-pathway; NRF2 pathway; Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling; Exercise-induced circadian regulation; Arachidonate epoxygenase / epoxide hydrolase; Metapathway biotransformation Phase I and II"	"Neutrophil degranulation; Paracetamol ADME; Detoxification of Reactive Oxygen Species; Glutathione conjugation"	"10"	"0"	"112.8"	"650.0"	"600.8"	"75.2"	"514.1"	"183.8"	"239.1"	"175.1"	"224.2"	"296.9"	"601.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P36957"	"Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLST PE=1 SV=4"	"5"	"2"	"6"	"2"	"453"	"48.7"	"8.95"	"1234.27"	"12.07"	"2"	"2"	"protein metabolism;other metabolic processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00198, Pf00364"	"1743"	"ENSG00000119689"	"DLST"	"B7Z5W8; E7ESY5; hsa:1743; P36957; Q7LDY7; Q9BQ32"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Metabolic reprogramming in colon cancer; 7q11.23 copy number variation syndrome; 1p36 copy number variation syndrome; 10q11.21q11.23 copy number variation syndrome; TCA cycle (aka Krebs or citric acid cycle)"	"Citric acid cycle (TCA cycle); Lysine catabolism; Glyoxylate metabolism and glycine degradation"	"10"	"0"	"150.6"	"307.9"	"328.1"	"114.6"	"293.7"	"141.7"	"302.7"	"214.7"	"337.6"	"420.8"	"622.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13242"	"Serine/arginine-rich splicing factor 9 OS=Homo sapiens OX=9606 GN=SRSF9 PE=1 SV=1"	"16"	"3"	"7"	"3"	"221"	"25.5"	"8.65"	"1104.94"	"12.04"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00076"	"8683"	"ENSG00000111786"	"SRSF9"	"hsa:8683; Q13242; Q52LD1"	"mRNA processing"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"6"	"0"	"287.8"	"473.5"	"536.6"	"288.2"	"513.4"	"327.4"	"501.3"	"337.4"	"455.5"	"448.2"	"634.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P54819"	"Adenylate kinase 2, mitochondrial OS=Homo sapiens OX=9606 GN=AK2 PE=1 SV=2"	"23"	"4"	"7"	"4"	"239"	"26.5"	"7.81"	"1889.19"	"11.98"	"4"	"3"	"other metabolic processes"	"cytoskeleton;mitochondrion;other cell component"	"kinase activity;other molecular function"	"Pf00406, Pf05191"	"204"	"ENSG00000004455"	"AK2"	"A8K6L1; B4DHH7; B4DL64; hsa:204; P54819; Q16856; Q5EB54; Q5TIF7; Q8TCY2; Q8TCY3"	""	"Interconversion of nucleotide di- and triphosphates"	"1"	"0"	"167.7"	"583.1"	"483.1"	"116.4"	"399.2"	"172.9"	"263.6"	"187.1"	"278.2"	"364.1"	"660.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14602"	"Eukaryotic translation initiation factor 1A, Y-chromosomal OS=Homo sapiens OX=9606 GN=EIF1AY PE=1 SV=4"	"22"	"4"	"6"	"4"	"144"	"16.4"	"5.24"	"1321.31"	"11.95"	"3"	"3"	"protein metabolism;other metabolic processes"	"other cell component"	"nucleic acid binding activity"	"Pf01176"	"9086"	"ENSG00000198692"	"EIF1AY"	"hsa:9086; O14602; Q9BS77"	"Translation factors"	""	"1"	"0"	"406.6"	"832.8"	"817.8"	"394.6"	"696.5"	"445.9"	"568.4"	"474.2"	"697.6"	"867.4"	"1426.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13136"	"Liprin-alpha-1 OS=Homo sapiens OX=9606 GN=PPFIA1 PE=1 SV=1"	"4"	"3"	"8"	"3"	"1202"	"135.7"	"6.29"	"1466.19"	"11.89"	"2"	"3"	"cell adhesion;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;other cell component"	""	"Pf00536, Pf07647"	"8500"	"ENSG00000131626"	"PPFIA1"	"A6NLE3; hsa:8500; Q13135; Q13136; Q14567; Q8N4I2"	""	"Glutamate Neurotransmitter Release Cycle; Serotonin Neurotransmitter Release Cycle; Norepinephrine Neurotransmitter Release Cycle; Dopamine Neurotransmitter Release Cycle; Acetylcholine Neurotransmitter Release Cycle; Receptor-type tyrosine-protein phosphatases"	"6"	"0"	"1339.4"	"1067.0"	"1274.9"	"979.9"	"1375.5"	"1196.3"	"1179.0"	"784.1"	"1165.7"	"1210.6"	"1532.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15942"	"Zyxin OS=Homo sapiens OX=9606 GN=ZYX PE=1 SV=1"	"8"	"3"	"6"	"3"	"572"	"61.2"	"6.67"	"1309.50"	"11.87"	"3"	"3"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00412"	"7791"	"ENSG00000159840; ENSG00000285443"	"ZYX"	"A4D2G6; B4DQX7; hsa:7791; Q15942; Q6I9S4"	"Integrin-mediated cell adhesion; Focal adhesion"	""	"2"	"0"	"148.2"	"245.9"	"269.7"	"119.9"	"275.4"	"125.9"	"276.8"	"204.4"	"252.8"	"307.8"	"443.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BTC0"	"Death-inducer obliterator 1 OS=Homo sapiens OX=9606 GN=DIDO1 PE=1 SV=5"	"2"	"3"	"5"	"3"	"2240"	"243.7"	"7.88"	"892.79"	"11.86"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes;signal transduction"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00628, Pf07500, Pf07744"	"11083"	"ENSG00000101191"	"DIDO1"	"A8MY65; B9EH82; E1P5I1; hsa:11083; O15043; Q3ZTL7; Q3ZTL8; Q4VXS1; Q4VXS2; Q4VXV8; Q4VXV9; Q96D72; Q9BQW0; Q9BTC0; Q9BW03; Q9H4G6; Q9H4G7; Q9NTU8; Q9NUM8; Q9UFB6"	""	""	"0"	"0"	"13.4"	"43.6"	"24.9"	"15.5"	"23.5"	"8.1"	"53.8"	"43.8"	"56.8"	"55.2"	"73.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P17480"	"Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF PE=1 SV=1"	"4"	"3"	"7"	"3"	"764"	"89.4"	"5.81"	"1477.60"	"11.80"	"3"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00505, Pf09011, Pf14887"	"7343"	"ENSG00000108312"	"UBTF"	"A8K6R8; hsa:7343; P17480"	"Ectoderm differentiation"	"NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; RNA Polymerase I Promoter Opening"	"6"	"0"	"75.8"	"150.3"	"189.7"	"71.2"	"165.6"	"85.3"	"256.3"	"220.4"	"361.7"	"636.9"	"1129.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P47914"	"60S ribosomal protein L29 OS=Homo sapiens OX=9606 GN=RPL29 PE=1 SV=2"	"18"	"3"	"7"	"3"	"159"	"17.7"	"11.66"	"1057.66"	"11.78"	"2"	"3"	"protein metabolism;other metabolic processes;developmental processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01779"	"6159"	"ENSG00000162244"	"RPL29"	"A8K0H3; B2R4M8; hsa:6159; P47914; Q6IPY3"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"339.9"	"461.6"	"514.1"	"284.6"	"581.9"	"390.6"	"1175.1"	"920.8"	"1123.6"	"1215.1"	"1546.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UN86"	"Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2"	"10"	"4"	"8"	"4"	"482"	"54.1"	"5.55"	"1320.66"	"11.74"	"4"	"4"	"cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf02136"	"9908"	"ENSG00000138757"	"G3BP2"	"A8K6X1; hsa:9908; O60606; O75149; Q9UN86; Q9UPA1"	""	"SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"1"	"0"	"147.2"	"379.2"	"359.7"	"131.4"	"338.8"	"156.8"	"305.1"	"258.9"	"317.9"	"395.8"	"613.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30153"	"Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4"	"7"	"5"	"10"	"5"	"589"	"65.3"	"5.11"	"2052.78"	"11.70"	"5"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02985"	"5518"	"ENSG00000105568"	"PPP2R1A"	"hsa:5518; P30153; Q13773; Q6ICQ3; Q96DH3"	"Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Wnt signaling pathway and pluripotency; PI3K-Akt signaling pathway; 16p11.2 proximal deletion syndrome; Glycogen synthesis and degradation; Cohesin complex - Cornelia de Lange syndrome"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Cyclin A/B1/B2 associated events during G2/M transition; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Spry regulation of FGF signaling; Negative regulation of MAPK pathway; ERKs are inactivated; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Regulation of TP53 Degradation; Cyclin D associated events in G1; Disassembly of the destruction complex and recruitment of AXIN to the membrane; RAF activation; Beta-catenin phosphorylation cascade; Signaling by GSK3beta mutants; CTNNB1 S33 mutants aren't phosphorylated; CTNNB1 S37 mutants aren't phosphorylated; CTNNB1 S45 mutants aren't phosphorylated; CTNNB1 T41 mutants aren't phosphorylated; APC truncation mutants have impaired AXIN binding; AXIN missense mutants destabilize the destruction complex; Truncations of AMER1 destabilize the destruction complex; MASTL Facilitates Mitotic Progression; Regulation of glycolysis by fructose 2,6-bisphosphate metabolism; Initiation of Nuclear Envelope (NE) Reformation; Platelet sensitization by LDL; CTLA4 inhibitory signaling; Inhibition of replication initiation of damaged DNA by RB1/E2F1; DARPP-32 events; PP2A-mediated dephosphorylation of key metabolic factors"	"49"	"0"	"148.6"	"466.5"	"463.6"	"143.2"	"432.9"	"205.2"	"289.5"	"247.2"	"355.5"	"452.6"	"728.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43768"	"Alpha-endosulfine OS=Homo sapiens OX=9606 GN=ENSA PE=1 SV=1"	"35"	"4"	"8"	"4"	"121"	"13.4"	"7.24"	"1436.72"	"11.69"	"4"	"4"	"cell cycle OR cell proliferation;other biological processes"	"nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf04667"	"2029"	"ENSG00000143420"	"ENSA"	"A8K1Z9; E9PB69; hsa:2029; O43768; Q5T5H2; Q68D48; Q6FHW0; Q6IAM4; Q6NUL2; Q6VUC6; Q6VUC7; Q6VUC8; Q6VUC9; Q6VUD0; Q6VUD1; Q9NRZ0"	""	"MASTL Facilitates Mitotic Progression"	"1"	"0"	"320.5"	"967.2"	"907.3"	"191.8"	"788.7"	"327.0"	"755.6"	"490.2"	"946.2"	"1461.0"	"2293.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UH65"	"Switch-associated protein 70 OS=Homo sapiens OX=9606 GN=SWAP70 PE=1 SV=1"	"7"	"4"	"7"	"4"	"585"	"69.0"	"5.87"	"1024.30"	"11.59"	"3"	"4"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00169"	"23075"	"ENSG00000133789"	"SWAP70"	"D3DQV1; hsa:23075; O75135; Q7LCY6; Q9P061; Q9P0Z8; Q9UH65"	""	"RAC1 GTPase cycle; RAC3 GTPase cycle; RAC2 GTPase cycle"	"3"	"0"	"127.2"	"258.7"	"286.2"	"122.8"	"263.2"	"158.5"	"260.3"	"242.5"	"673.9"	"1574.9"	"3239.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35580"	"Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3"	"3"	"5"	"7"	"2"	"1976"	"228.9"	"5.54"	"771.25"	"11.58"	"3"	"4"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00063, Pf00612, Pf01576, Pf02736"	"4628"	"ENSG00000133026"	"MYH10"	"B2RWP9; D3DTS1; F8VTL3; hsa:4628; P35580; Q12989; Q149N3; Q149N4; Q16087; Q4LE45; Q6PK16; Q9BWG0"	"Regulation of actin cytoskeleton"	"EPHA-mediated growth cone collapse; RHO GTPases activate PAKs; RHO GTPases activate CIT; Sema4D induced cell migration and growth-cone collapse; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs"	"7"	"0"	"49.4"	"110.9"	"147.4"	"34.0"	"113.3"	"45.7"	"101.0"	"91.1"	"114.0"	"175.1"	"288.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P016"	"Thymocyte nuclear protein 1 OS=Homo sapiens OX=9606 GN=THYN1 PE=1 SV=1"	"20"	"4"	"7"	"4"	"225"	"25.7"	"9.25"	"1050.13"	"11.56"	"3"	"4"	""	""	""	"Pf01878"	"29087"	"ENSG00000151500"	"THYN1"	"hsa:29087; Q567Q2; Q9H3L4; Q9HC20; Q9P016"	""	""	"0"	"0"	"123.0"	"253.4"	"252.3"	"120.9"	"224.0"	"117.4"	"319.1"	"294.7"	"385.8"	"449.0"	"680.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14635"	"G2/mitotic-specific cyclin-B1 OS=Homo sapiens OX=9606 GN=CCNB1 PE=1 SV=1"	"9"	"4"	"7"	"4"	"433"	"48.3"	"7.47"	"1204.08"	"11.56"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00134, Pf02984"	"891"	"ENSG00000134057"	"CCNB1"	"A8K066; hsa:891; P14635; Q5TZP9"	"AMP-activated protein kinase signaling; miRNA regulation of DNA damage response; Cell cycle; Retinoblastoma gene in cancer; ATM signaling pathway; G1 to S cell cycle control; GDNF signaling; DNA damage response"	"The role of GTSE1 in G2/M progression after G2 checkpoint; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Resolution of Sister Chromatid Cohesion; Nuclear Pore Complex (NPC) Disassembly; Regulation of PLK1 Activity at G2/M Transition; APC/C:Cdc20 mediated degradation of Cyclin B; Phosphorylation of the APC/C; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; Cyclin A/B1/B2 associated events during G2/M transition; Transcriptional regulation by RUNX2; MASTL Facilitates Mitotic Progression; E2F-enabled inhibition of pre-replication complex formation; Golgi Cisternae Pericentriolar Stack Reorganization; Condensation of Prophase Chromosomes; Initiation of Nuclear Envelope (NE) Reformation; Polo-like kinase mediated events; Condensation of Prometaphase Chromosomes; Activation of NIMA Kinases NEK9, NEK6, NEK7; G2/M DNA replication checkpoint; Depolymerization of the Nuclear Lamina; Phosphorylation of Emi1"	"31"	"0"	"122.2"	"201.3"	"219.6"	"98.0"	"212.8"	"154.0"	"835.9"	"521.6"	"809.4"	"1016.2"	"1146.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H444"	"Charged multivesicular body protein 4b OS=Homo sapiens OX=9606 GN=CHMP4B PE=1 SV=1"	"21"	"6"	"9"	"6"	"224"	"24.9"	"4.82"	"1751.20"	"11.53"	"5"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf03357"	"128866"	"ENSG00000101421"	"CHMP4B"	"E1P5N4; hsa:128866; Q53ZD6; Q9H444"	""	"Sealing of the nuclear envelope (NE) by ESCRT-III; HCMV Late Events; Budding and maturation of HIV virion; Endosomal Sorting Complex Required For Transport (ESCRT); Late endosomal microautophagy; Macroautophagy; Pyroptosis; Translation of Replicase and Assembly of the Replication Transcription Complex; Translation of Replicase and Assembly of the Replication Transcription Complex"	"9"	"0"	"603.1"	"1267.5"	"1292.2"	"496.3"	"1188.0"	"604.7"	"863.0"	"758.1"	"1135.4"	"1398.2"	"1819.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23919"	"Thymidylate kinase OS=Homo sapiens OX=9606 GN=DTYMK PE=1 SV=4"	"9"	"3"	"7"	"3"	"212"	"23.8"	"8.27"	"1035.78"	"11.52"	"2"	"3"	"other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf02223"	"1841"	"ENSG00000168393"	"DTYMK"	"B7ZW70; hsa:1841; P23919; Q6FGX1; Q9BUX4"	"Pyrimidine metabolism; 2q37 copy number variation syndrome"	"Interconversion of nucleotide di- and triphosphates"	"3"	"0"	"61.0"	"223.8"	"190.2"	"53.6"	"156.8"	"63.3"	"118.1"	"119.2"	"145.4"	"207.3"	"383.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UPT8"	"Zinc finger CCCH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=ZC3H4 PE=1 SV=3"	"5"	"3"	"4"	"3"	"1303"	"140.2"	"6.27"	"410.13"	"11.50"	"1"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00642, Pf14608, Pf18044"	"23211"	"ENSG00000130749"	"ZC3H4"	"hsa:23211; Q9UPT8; Q9Y420"	""	""	"0"	"0"	"39.9"	"53.7"	"44.3"	"34.2"	"49.4"	"35.1"	"62.3"	"53.1"	"71.6"	"68.8"	"66.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16630"	"Cleavage and polyadenylation specificity factor subunit 6 OS=Homo sapiens OX=9606 GN=CPSF6 PE=1 SV=2"	"11"	"4"	"6"	"4"	"551"	"59.2"	"7.15"	"633.50"	"11.49"	"2"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00076"	"11052"	"ENSG00000111605"	"CPSF6"	"A8K7K9; hsa:11052; Q16630; Q53ES1; Q9BSJ7; Q9BW18"	""	"Signaling by cytosolic FGFR1 fusion mutants; Signaling by FGFR1 in disease"	"2"	"0"	"123.9"	"270.6"	"242.2"	"109.1"	"237.2"	"138.1"	"253.3"	"212.5"	"302.4"	"389.9"	"509.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14192"	"Four and a half LIM domains protein 2 OS=Homo sapiens OX=9606 GN=FHL2 PE=1 SV=3"	"16"	"4"	"10"	"4"	"279"	"32.2"	"7.55"	"1210.41"	"11.48"	"2"	"4"	"RNA metabolism OR transcription;developmental processes;other biological processes"	"cytoskeleton;nucleus"	"other molecular function"	"Pf00412"	"2274"	"ENSG00000115641"	"FHL2"	"hsa:2274; Q13229; Q13644; Q14192; Q2I5I4; Q5TM15; Q9P294"	"Androgen receptor signaling pathway; RANKL/RANK signaling pathway; Ectoderm differentiation; VEGFA-VEGFR2 signaling; 11p11.2 copy number variation syndrome"	"PPARA activates gene expression"	"6"	"0"	"253.0"	"487.0"	"439.8"	"220.7"	"406.4"	"236.6"	"451.6"	"457.8"	"535.1"	"823.9"	"1060.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q00169"	"Phosphatidylinositol transfer protein alpha isoform OS=Homo sapiens OX=9606 GN=PITPNA PE=1 SV=2"	"16"	"3"	"5"	"2"	"270"	"31.8"	"6.55"	"680.57"	"11.46"	"2"	"3"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf02121"	"5306"	"ENSG00000174238"	"PITPNA"	"hsa:5306; Q00169"	""	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Role of second messengers in netrin-1 signaling"	"2"	"0"	"191.5"	"191.5"	"232.9"	"104.4"	"209.9"	"140.6"	"214.4"	"135.4"	"232.5"	"245.2"	"256.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22087"	"rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2"	"12"	"3"	"6"	"3"	"321"	"33.8"	"10.18"	"1387.70"	"11.46"	"3"	"3"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf01269"	"2091"	"ENSG00000105202; ENSG00000280548"	"FBL"	"B5BUE8; hsa:2091; O75259; P22087; Q6IAT5; Q9UPI6"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"43.7"	"96.0"	"99.9"	"36.6"	"93.1"	"44.2"	"117.4"	"115.4"	"251.0"	"322.9"	"353.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H0D6"	"5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1"	"4"	"4"	"8"	"4"	"950"	"108.5"	"7.47"	"1332.56"	"11.44"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03159, Pf17846"	"22803"	"ENSG00000088930"	"XRN2"	"hsa:22803; Q3L8N4; Q6KGZ9; Q9BQL1; Q9H0D6; Q9NTW0; Q9NXS6; Q9UL53"	"mRNA processing"	"Major pathway of rRNA processing in the nucleolus and cytosol; Association of TriC/CCT with target proteins during biosynthesis"	"3"	"0"	"137.5"	"300.5"	"320.1"	"120.0"	"309.3"	"152.5"	"304.8"	"257.9"	"355.4"	"443.3"	"571.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z739"	"YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1"	"7"	"4"	"7"	"3"	"585"	"63.8"	"9.04"	"1487.87"	"11.43"	"4"	"3"	"cell organization and biogenesis;other biological processes"	"cytosol;other cell component"	"translation activity;nucleic acid binding activity"	"Pf04146"	"253943"	"ENSG00000185728"	"YTHDF3"	"B3KXL4; hsa:253943; Q63Z37; Q659A3; Q7Z739"	""	""	"0"	"1"	"176.8"	"447.8"	"465.0"	"158.9"	"401.7"	"208.3"	"764.8"	"639.0"	"951.9"	"1337.9"	"2028.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q93009"	"Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2"	"7"	"6"	"11"	"6"	"1102"	"128.2"	"5.55"	"2097.03"	"11.43"	"6"	"5"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00443, Pf00917, Pf12436, Pf14533"	"7874"	"ENSG00000187555"	"USP7"	"A6NMY8; B7Z815; H0Y3G8; hsa:7874; Q93009"	"Nucleotide excision repair in xeroderma pigmentosum"	"Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Ub-specific processing proteases; Regulation of TP53 Degradation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Regulation of PTEN localization"	"9"	"0"	"202.7"	"383.7"	"353.2"	"176.3"	"362.2"	"239.6"	"349.6"	"283.1"	"396.9"	"440.6"	"613.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P28074"	"Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3"	"13"	"3"	"6"	"3"	"263"	"28.5"	"6.92"	"1303.12"	"11.43"	"3"	"3"	"protein metabolism;other metabolic processes;stress response"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00227"	"5693"	"ENSG00000100804"	"PSMB5"	"B2R4N9; B4DUM9; D3DS43; E9PAV2; hsa:5693; P28074; Q16242; Q6PEW2; Q7Z3B5; Q86T01; Q9TNN9"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Regulation of expression of SLITs and ROBOs; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; SCF(Skp2)-mediated degradation of p27/p21; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"62"	"0"	"116.4"	"256.7"	"263.3"	"114.3"	"300.6"	"143.0"	"239.5"	"204.6"	"280.3"	"418.5"	"678.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00764"	"Pyridoxal kinase OS=Homo sapiens OX=9606 GN=PDXK PE=1 SV=1"	"11"	"3"	"4"	"3"	"312"	"35.1"	"6.13"	"262.08"	"11.41"	"1"	"3"	"other metabolic processes"	"non-structural extracellular;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf08543"	"8566"	"ENSG00000160209"	"PDXK"	"hsa:8566; O00764; Q7Z2Y0; Q9BS02"	""	"Neutrophil degranulation; Vitamins B6 activation to pyridoxal phosphate"	"2"	"0"	"3.2"	"30.6"	"20.8"	"3.4"	"24.4"	"7.7"	"5.0"	"6.2"	"7.8"	"10.9"	"28.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94832"	"Unconventional myosin-Id OS=Homo sapiens OX=9606 GN=MYO1D PE=1 SV=2"	"5"	"5"	"9"	"5"	"1006"	"116.1"	"9.39"	"1434.94"	"11.39"	"5"	"4"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00063, Pf00612, Pf06017"	"4642"	"ENSG00000176658"	"MYO1D"	"A6H8V3; hsa:4642; O94832; Q8NHP9"	""	""	"0"	"0"	"60.2"	"146.9"	"161.6"	"54.6"	"133.7"	"63.2"	"178.4"	"227.5"	"627.9"	"1127.7"	"1617.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14444"	"Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2"	"6"	"4"	"8"	"4"	"709"	"78.3"	"5.25"	"1206.30"	"11.37"	"4"	"4"	"cell organization and biogenesis;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf12287, Pf18293"	"4076"	"ENSG00000135387"	"CAPRIN1"	"A6NMY7; D3DR06; hsa:4076; Q14444; Q15074; Q6IMN4; Q6IMN7; Q9BV09"	""	""	"0"	"0"	"172.9"	"386.7"	"366.2"	"169.5"	"322.6"	"204.4"	"1547.1"	"1145.4"	"1319.5"	"1499.8"	"1943.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13576"	"Ras GTPase-activating-like protein IQGAP2 OS=Homo sapiens OX=9606 GN=IQGAP2 PE=1 SV=4"	"4"	"6"	"9"	"5"	"1575"	"180.5"	"5.64"	"1465.81"	"11.34"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00307, Pf00612, Pf00616, Pf03836"	"10788"	"ENSG00000145703"	"IQGAP2"	"A8K4V1; B7Z8A4; hsa:10788; J3KR91; Q13576"	"Ciliary landscape; G13 signaling pathway"	"Neutrophil degranulation; RHO GTPases activate IQGAPs; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOG GTPase cycle"	"7"	"0"	"122.9"	"269.7"	"268.7"	"99.9"	"270.4"	"140.3"	"352.6"	"700.6"	"822.3"	"859.4"	"1225.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IWZ6"	"Bardet-Biedl syndrome 7 protein OS=Homo sapiens OX=9606 GN=BBS7 PE=1 SV=2"	"6"	"4"	"6"	"4"	"715"	"80.3"	"6.05"	"674.86"	"11.27"	"2"	"4"	"cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	""	"55212"	"ENSG00000138686"	"BBS7"	"hsa:55212; Q4W5P8; Q8IWZ6; Q8N581; Q9NVI4"	"Ciliary landscape; Genes related to primary cilium development (based on CRISPR); Joubert syndrome; Ciliopathies; Bardet-Biedl syndrome"	"BBSome-mediated cargo-targeting to cilium"	"6"	"0"	"34.7"	"67.1"	"69.5"	"33.9"	"70.5"	"54.7"	"123.4"	"259.9"	"680.7"	"958.5"	"1056.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P28066"	"Proteasome subunit alpha type-5 OS=Homo sapiens OX=9606 GN=PSMA5 PE=1 SV=3"	"17"	"3"	"6"	"3"	"241"	"26.4"	"4.79"	"1208.64"	"11.23"	"3"	"3"	"protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	""	"Pf00227, Pf10584"	"5686"	"ENSG00000143106"	"PSMA5"	"B2R8F6; B4E2V4; hsa:5686; P28066; Q3T1C1; Q6IBF7"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"UCH proteinases; Separation of Sister Chromatids; Neutrophil degranulation; Ub-specific processing proteases; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"63"	"0"	"77.3"	"195.0"	"215.9"	"86.9"	"189.7"	"98.3"	"201.6"	"167.1"	"207.5"	"281.0"	"480.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63167"	"Dynein light chain 1, cytoplasmic OS=Homo sapiens OX=9606 GN=DYNLL1 PE=1 SV=1"	"33"	"2"	"4"	"2"	"89"	"10.4"	"7.40"	"266.43"	"11.20"	"1"	"2"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01221"	"8655"	"ENSG00000088986"	"DYNLL1"	"hsa:8655; P63167; Q15701"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein; Genes related to primary cilium development (based on CRISPR); 3q29 copy number variation syndrome"	"MHC class II antigen presentation; COPI-mediated anterograde transport; Neutrophil degranulation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-independent Golgi-to-ER retrograde traffic; Intraflagellar transport; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Recruitment of NuMA to mitotic centrosomes; RHO GTPases Activate Formins; HCMV Early Events; Aggrephagy; EML4 and NUDC in mitotic spindle formation; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Macroautophagy; Activation of BIM and translocation to mitochondria"	"27"	"0"	"172.1"	"304.9"	"392.5"	"158.6"	"355.8"	"260.7"	"341.3"	"240.9"	"360.5"	"445.7"	"649.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75822"	"Eukaryotic translation initiation factor 3 subunit J OS=Homo sapiens OX=9606 GN=EIF3J PE=1 SV=2"	"15"	"5"	"8"	"5"	"258"	"29.0"	"4.83"	"1755.56"	"11.17"	"3"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf08597"	"8669"	"ENSG00000104131"	"EIF3J"	"B4DUI3; F5H425; hsa:8669; O75822; Q9BUD2; Q9H8Q2; Q9UI65"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"8"	"0"	"452.2"	"892.7"	"996.0"	"474.1"	"967.1"	"584.9"	"791.6"	"546.6"	"926.7"	"1097.9"	"1732.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NVI7"	"ATPase family AAA domain-containing protein 3A OS=Homo sapiens OX=9606 GN=ATAD3A PE=1 SV=2"	"8"	"5"	"7"	"1"	"634"	"71.3"	"8.98"	"875.00"	"11.16"	"3"	"4"	"cell organization and biogenesis;stress response;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf00004, Pf12037"	"55210"	"ENSG00000197785"	"ATAD3A"	"B3KPB3; D2K8Q1; G3V1I6; hsa:55210; Q5SV23; Q8N275; Q96A50; Q9NVI7"	"1p36 copy number variation syndrome"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q969S3"	"Zinc finger protein 622 OS=Homo sapiens OX=9606 GN=ZNF622 PE=1 SV=1"	"11"	"5"	"9"	"5"	"477"	"54.2"	"6.15"	"1720.86"	"11.15"	"3"	"3"	"signal transduction;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf12171, Pf12756"	"90441"	"ENSG00000173545"	"ZNF622"	"hsa:90441; Q969S3"	""	""	"0"	"0"	"156.8"	"293.7"	"262.2"	"139.6"	"270.3"	"139.2"	"419.4"	"364.7"	"518.5"	"642.5"	"833.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P36915"	"Guanine nucleotide-binding protein-like 1 OS=Homo sapiens OX=9606 GN=GNL1 PE=1 SV=2"	"7"	"3"	"6"	"3"	"607"	"68.6"	"5.80"	"1076.99"	"11.13"	"3"	"3"	"stress response;signal transduction;other biological processes"	"non-structural extracellular"	"other molecular function"	"Pf01926"	"2794"	"ENSG00000204590; ENSG00000206492; ENSG00000226882; ENSG00000228581; ENSG00000229470; ENSG00000232143; ENSG00000235986"	"GNL1"	"B0S838; hsa:2794; P36915; Q96CT5"	""	""	"0"	"0"	"48.6"	"112.1"	"111.9"	"41.3"	"108.1"	"65.5"	"91.2"	"65.3"	"94.8"	"109.6"	"157.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5JSZ5"	"Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2"	"2"	"4"	"7"	"3"	"2229"	"242.8"	"8.34"	"958.79"	"11.12"	"3"	"4"	"other biological processes"	""	""	"Pf07001"	"84726"	"ENSG00000288701"	"PRRC2B"	"hsa:84726; O60270; Q5JSZ5; Q5JSZ7; Q66VZ2; Q68CR0; Q96EI9; Q9H683"	""	""	"0"	"0"	"138.0"	"123.2"	"168.0"	"99.9"	"187.2"	"127.2"	"211.8"	"134.6"	"198.9"	"206.2"	"241.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14671"	"Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3"	"4"	"3"	"6"	"3"	"1186"	"126.4"	"6.84"	"1254.15"	"11.11"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00806"	"9698"	"ENSG00000134644"	"PUM1"	"A8K6W4; B4DG92; D3DPN3; E9PCJ0; hsa:9698; Q14671; Q53HH5; Q5VXY7; Q9HAN1"	""	"Golgi Associated Vesicle Biogenesis"	"1"	"0"	"77.3"	"175.1"	"159.7"	"60.9"	"144.1"	"65.3"	"110.6"	"109.5"	"147.6"	"201.8"	"299.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P12268"	"Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2"	"11"	"5"	"10"	"5"	"514"	"55.8"	"6.90"	"2923.93"	"11.10"	"5"	"3"	"cell cycle OR cell proliferation;other metabolic processes;developmental processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00478, Pf00571"	"3615"	"ENSG00000178035"	"IMPDH2"	"hsa:3615; P12268; Q6LEF3"	"Rett syndrome causing genes"	"Potential therapeutics for SARS; Neutrophil degranulation; Purine ribonucleoside monophosphate biosynthesis; Azathioprine ADME"	"5"	"0"	"125.6"	"899.4"	"676.0"	"60.9"	"523.0"	"135.9"	"244.4"	"195.1"	"266.9"	"365.2"	"762.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61586"	"Transforming protein RhoA OS=Homo sapiens OX=9606 GN=RHOA PE=1 SV=1"	"17"	"3"	"11"	"3"	"193"	"21.8"	"6.10"	"1734.76"	"11.09"	"3"	"3"	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00071"	"387"	"ENSG00000067560"	"RHOA"	"hsa:387; P06749; P61586; Q53HM4; Q5U024; Q9UDJ0; Q9UEJ4"	"Androgen receptor signaling pathway; Physiological and pathological hypertrophy of the heart; MicroRNAs in cardiomyocyte hypertrophy; Leptin signaling pathway; Pathogenic Escherichia coli infection; AGE/RAGE pathway; Corticotropin-releasing hormone signaling pathway; Spinal cord injury; Alpha 6 beta 4 signaling pathway; Focal adhesion; G protein signaling pathways; Wnt signaling pathway; Hypothetical craniofacial development pathway; Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; Wnt signaling pathway and pluripotency; Fibrin complement receptor 3 signaling pathway; Wnt signaling in kidney disease; Chromosomal and microsatellite instability in colorectal cancer ; Ebola virus infection in host; Ras signaling; Pancreatic adenocarcinoma pathway; Wnt signaling; Envelope proteins and their potential roles in EDMD physiopathology; Hippo signaling regulation pathways; Leukocyte-intrinsic Hippo pathway functions; Neural crest cell migration during development; Neural crest cell migration in cancer; Joubert syndrome; Gastrin signaling pathway; Netrin-UNC5B signaling pathway; mBDNF and proBDNF regulation of GABA neurotransmission; MAP3K1 role in promoting and blocking gonadal determination; Airway smooth muscle cell contraction; RAS and bradykinin pathways in COVID-19; Regulation of actin cytoskeleton; GDNF signaling; PtdIns(4,5)P2 in cytokinesis pathway; 2q11.2 copy number variation syndrome; 2q21.1 copy number variation syndrome; G13 signaling pathway; 8p23.1 copy number variation syndrome; DNA damage response (only ATM dependent); Serotonin HTR1 group and FOS pathway"	"Neutrophil degranulation; RHOC GTPase cycle; RHOA GTPase cycle; G alpha (12/13) signalling events; RHO GTPases Activate Formins; EPHB-mediated forward signaling; GPVI-mediated activation cascade; PI3K/AKT activation; VEGFA-VEGFR2 Pathway; ERBB2 Regulates Cell Motility; RHO GTPases activate CIT; G beta:gamma signalling through PI3Kgamma; PCP/CE pathway; RHO GTPases Activate Rhotekin and Rhophilins; EPHA-mediated growth cone collapse; Sema4D induced cell migration and growth-cone collapse; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; Sema4D mediated inhibition of cell attachment and migration; Ovarian tumor domain proteases; SLIT2:ROBO1 increases RHOA activity; PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases; TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition); Axonal growth stimulation; Axonal growth inhibition (RHOA activation); RHO GTPases activate KTN1"	"70"	"0"	"97.3"	"225.0"	"228.4"	"80.5"	"211.5"	"84.8"	"296.2"	"206.2"	"258.0"	"258.0"	"344.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NFJ9"	"Bardet-Biedl syndrome 1 protein OS=Homo sapiens OX=9606 GN=BBS1 PE=1 SV=1"	"9"	"3"	"6"	"3"	"593"	"65.0"	"7.93"	"1124.20"	"11.03"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf14779"	"582"	"ENSG00000174483"	"BBS1"	"hsa:582; Q32MM9; Q32MN0; Q8NFJ9; Q96SN4"	"Ciliary landscape; Genes related to primary cilium development (based on CRISPR); Joubert syndrome; Ciliopathies; Bardet-Biedl syndrome"	"BBSome-mediated cargo-targeting to cilium"	"6"	"0"	"51.5"	"83.5"	"104.9"	"52.7"	"125.0"	"66.7"	"100.8"	"101.5"	"188.2"	"269.7"	"335.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92665"	"28S ribosomal protein S31, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS31 PE=1 SV=3"	"14"	"5"	"7"	"5"	"395"	"45.3"	"9.29"	"996.04"	"11.03"	"3"	"4"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf15433"	"10240"	"ENSG00000102738"	"MRPS31"	"B2RCS3; hsa:10240; Q5VYC8; Q8WTV8; Q92665"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"148.8"	"332.1"	"316.3"	"141.3"	"310.9"	"151.3"	"321.3"	"264.9"	"491.8"	"681.0"	"1106.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P24941"	"Cyclin-dependent kinase 2 OS=Homo sapiens OX=9606 GN=CDK2 PE=1 SV=2"	"11"	"4"	"6"	"2"	"298"	"33.9"	"8.68"	"633.01"	"11.01"	"1"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"1017"	"ENSG00000123374"	"CDK2"	"A8K7C6; hsa:1017; O75100; P24941"	"miRNA regulation of DNA damage response; Cell cycle; Thyroid stimulating hormone (TSH) signaling pathway; Glioblastoma signaling pathways; Oncostatin M signaling pathway; Spinal cord injury; Retinoblastoma gene in cancer; Aryl hydrocarbon receptor pathway; Vitamin D receptor pathway; PI3K-Akt signaling pathway; G1 to S cell cycle control; Measles virus infection; Small cell lung cancer; DNA replication; p53 transcriptional gene network; Pleural mesothelioma; Sphingolipid metabolism in senescence; Urotensin-II-mediated signaling pathway; ID signaling pathway; TROP2 regulatory signaling; DNA damage response"	"TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; Regulation of TP53 Degradation; SCF(Skp2)-mediated degradation of p27/p21; Regulation of TP53 Activity through Phosphorylation; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; G2 Phase; Cyclin D associated events in G1; Defective binding of RB1 mutants to E2F1,(E2F2, E2F3); Telomere Extension By Telomerase; Regulation of APC/C activators between G1/S and early anaphase; Senescence-Associated Secretory Phenotype (SASP); Factors involved in megakaryocyte development and platelet production; Processing of DNA double-strand break ends; Cyclin A/B1/B2 associated events during G2/M transition; Meiotic recombination; DNA Damage/Telomere Stress Induced Senescence; Transcriptional regulation of granulopoiesis; G0 and Early G1; Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes; p53-Dependent G1 DNA Damage Response; PTK6 Regulates Cell Cycle"	"47"	"0"	"156.2"	"360.4"	"369.2"	"137.2"	"333.8"	"172.5"	"296.0"	"464.2"	"602.3"	"731.5"	"1568.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q2NL82"	"Pre-rRNA-processing protein TSR1 homolog OS=Homo sapiens OX=9606 GN=TSR1 PE=1 SV=1"	"6"	"4"	"7"	"4"	"804"	"91.8"	"7.42"	"1397.34"	"10.98"	"4"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04950, Pf08142"	"55720"	"ENSG00000167721"	"TSR1"	"hsa:55720; Q2NL82; Q8WUY5; Q9NVT0; Q9P2E6"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"143.1"	"189.0"	"242.9"	"130.6"	"246.7"	"180.5"	"415.2"	"298.4"	"491.4"	"539.2"	"658.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P37802"	"Transgelin-2 OS=Homo sapiens OX=9606 GN=TAGLN2 PE=1 SV=3"	"27"	"4"	"6"	"4"	"199"	"22.4"	"8.25"	"1248.63"	"10.97"	"3"	"3"	"cell organization and biogenesis;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton"	"cytoskeletal activity"	"Pf00307, Pf00402"	"8407"	"ENSG00000158710"	"TAGLN2"	"E9KL39; hsa:8407; P37802; Q5JRQ6; Q5JRQ7; Q6FGI1; Q9BUH5; Q9H4P0"	""	"Platelet degranulation"	"1"	"0"	"33.6"	"280.2"	"251.8"	"18.8"	"188.6"	"55.4"	"84.7"	"51.5"	"81.3"	"104.5"	"248.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05091"	"Aldehyde dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH2 PE=1 SV=2"	"6"	"3"	"6"	"3"	"517"	"56.3"	"7.05"	"1141.90"	"10.95"	"3"	"3"	"other metabolic processes;other biological processes"	"mitochondrion"	"other molecular function"	"Pf00171"	"217"	"ENSG00000111275"	"ALDH2"	"B4DW54; E7EUE5; hsa:217; P05091; Q03639; Q6IB13; Q6IV71"	"Fatty acid omega-oxidation; Ethanol effects on histone modifications; Tryptophan metabolism; Fluoroacetic acid toxicity"	"Smooth Muscle Contraction; Ethanol oxidation; Metabolism of serotonin"	"7"	"0"	"90.4"	"433.5"	"365.1"	"60.3"	"333.0"	"116.1"	"156.0"	"129.6"	"188.4"	"248.3"	"409.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09493"	"Tropomyosin alpha-1 chain OS=Homo sapiens OX=9606 GN=TPM1 PE=1 SV=2"	"18"	"6"	"11"	"1"	"284"	"32.7"	"4.74"	"2224.28"	"10.90"	"6"	"5"	"cell organization and biogenesis;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00261"	"7168"	"ENSG00000140416"	"TPM1"	"B7Z5T7; D9YZV2; D9YZV3; D9YZV8; hsa:7168; P09493; P09494; P10469; Q6DV89; Q6DV90; Q7Z6L8; Q86W64; Q96IK2; Q9UCI1; Q9UCI2; Q9UCY9; Q9Y427"	"Vitamin D receptor pathway; Striated muscle contraction pathway"	"Smooth Muscle Contraction; Striated Muscle Contraction"	"4"	"0"	"10.7"	"103.5"	"83.8"	"7.2"	"56.8"	"11.4"	"30.5"	"14.5"	"29.4"	"30.4"	"98.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P38117"	"Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3"	"18"	"5"	"10"	"5"	"255"	"27.8"	"8.10"	"1728.65"	"10.89"	"5"	"4"	"other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf01012"	"2109"	"ENSG00000105379"	"ETFB"	"A8K766; B3KNY2; hsa:2109; P38117; Q6IBH7; Q71RF6; Q9Y3S7"	""	"Respiratory electron transport; Protein methylation"	"2"	"0"	"99.7"	"488.6"	"361.5"	"53.1"	"308.9"	"108.5"	"153.2"	"141.5"	"189.0"	"241.7"	"438.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25398"	"40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3"	"29"	"5"	"9"	"5"	"132"	"14.5"	"7.21"	"1828.90"	"10.88"	"4"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01248"	"6206"	"ENSG00000112306"	"RPS12"	"hsa:6206; P25398; Q76M58"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"342.7"	"596.6"	"655.5"	"323.7"	"667.2"	"408.8"	"931.6"	"659.4"	"944.6"	"1068.3"	"1379.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5T9A4"	"ATPase family AAA domain-containing protein 3B OS=Homo sapiens OX=9606 GN=ATAD3B PE=1 SV=1"	"6"	"5"	"8"	"1"	"648"	"72.5"	"9.20"	"1148.46"	"10.87"	"4"	"4"	"cell organization and biogenesis"	"plasma membrane;other membranes;mitochondrion"	"other molecular function"	"Pf00004, Pf12037"	"83858"	"ENSG00000160072"	"ATAD3B"	"A8K3H1; hsa:83858; Q5T9A4; Q6ZRB5; Q9BUK4; Q9ULE7"	"1p36 copy number variation syndrome"	"Neutrophil degranulation"	"2"	"3"	"247.3"	"753.2"	"785.9"	"208.6"	"666.2"	"220.0"	"608.0"	"521.1"	"747.2"	"1009.0"	"1483.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11310"	"Medium-chain specific acyl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ACADM PE=1 SV=1"	"12"	"3"	"5"	"3"	"421"	"46.6"	"8.37"	"752.18"	"10.87"	"2"	"3"	"other metabolic processes;stress response;developmental processes;other biological processes"	"other membranes;mitochondrion;other cell component"	"other molecular function"	"Pf00441, Pf02770, Pf02771"	"34"	"ENSG00000117054"	"ACADM"	"hsa:34; P11310; Q5T4U4; Q9NYF1"	"Fatty acid beta-oxidation; PPAR-alpha pathway; Nuclear receptors meta-pathway; Mitochondrial long chain fatty acid beta-oxidation; Amino acid metabolism; PPAR signaling pathway; Mitochondrial fatty acid oxidation disorders; Female steroid hormones in cardiomyocyte energy metabolism; Sudden infant death syndrome (SIDS) susceptibility pathways"	"PPARA activates gene expression; mitochondrial fatty acid beta-oxidation of unsaturated fatty acids; Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA"	"13"	"0"	"107.9"	"410.4"	"407.6"	"97.0"	"335.4"	"158.3"	"334.1"	"248.3"	"329.8"	"395.7"	"703.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P01591"	"Immunoglobulin J chain OS=Homo sapiens OX=9606 GN=JCHAIN PE=1 SV=4"	"9"	"2"	"6"	"2"	"159"	"18.1"	"5.24"	"1101.37"	"10.85"	"2"	"2"	"cell organization and biogenesis;stress response;other biological processes"	"non-structural extracellular"	"signal transduction activity or receptor binding;other molecular function"	"Pf15097"	"3512"	"ENSG00000132465"	"JCHAIN"	"hsa:3512; P01591"	""	"Cell surface interactions at the vascular wall; Scavenging of heme from plasma"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P27694"	"Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2"	"13"	"6"	"8"	"6"	"616"	"68.1"	"7.21"	"1203.26"	"10.83"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01336, Pf04057, Pf08646, Pf16900"	"6117"	"ENSG00000132383"	"RPA1"	"A8K0Y9; hsa:6117; P27694; Q59ES9"	"Homologous recombination; Retinoblastoma gene in cancer; ATR signaling; G1 to S cell cycle control; DNA replication; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"SUMOylation of DNA damage response and repair proteins; PCNA-Dependent Long Patch Base Excision Repair; Fanconi Anemia Pathway; Regulation of HSF1-mediated heat shock response; Regulation of TP53 Activity through Phosphorylation; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Meiotic recombination; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; HSF1 activation; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; Dual Incision in GG-NER; Removal of the Flap Intermediate; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"39"	"0"	"328.8"	"795.1"	"694.9"	"260.0"	"671.4"	"365.8"	"428.4"	"277.7"	"431.1"	"588.8"	"870.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49406"	"39S ribosomal protein L19, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL19 PE=1 SV=2"	"14"	"4"	"7"	"4"	"292"	"33.5"	"9.50"	"887.43"	"10.83"	"3"	"4"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf01245"	"9801"	"ENSG00000115364"	"MRPL19"	"hsa:9801; P49406; Q53TX9; Q96Q52"	"Cytoplasmic ribosomal proteins"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"4"	"0"	"49.1"	"102.6"	"95.7"	"39.3"	"87.0"	"53.0"	"86.3"	"74.3"	"92.6"	"125.9"	"171.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06737"	"Glycogen phosphorylase, liver form OS=Homo sapiens OX=9606 GN=PYGL PE=1 SV=4"	"6"	"4"	"8"	"4"	"847"	"97.1"	"7.17"	"1116.91"	"10.78"	"4"	"4"	"other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;other cell component"	"other molecular function"	"Pf00343"	"5836"	"ENSG00000100504"	"PYGL"	"A6NDQ4; B4DUB7; F5H816; hsa:5836; O60567; O60752; O60913; P06737; Q501V9; Q641R5; Q96G82"	"TNF-alpha signaling pathway; Glycogen synthesis and degradation; Disorders of galactose metabolism"	"Neutrophil degranulation; Glycogen breakdown (glycogenolysis)"	"5"	"0"	"28.8"	"234.2"	"193.0"	"28.8"	"197.4"	"54.4"	"71.4"	"49.0"	"75.8"	"102.5"	"204.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30086"	"Phosphatidylethanolamine-binding protein 1 OS=Homo sapiens OX=9606 GN=PEBP1 PE=1 SV=3"	"24"	"4"	"7"	"4"	"187"	"21.0"	"7.53"	"1651.99"	"10.77"	"4"	"3"	"other biological processes"	"cytosol"	"enzyme regulator activity;other molecular function"	"Pf01161"	"5037"	"ENSG00000089220"	"PEBP1"	"B2R4S1; hsa:5037; P30086"	"Pancreatic adenocarcinoma pathway; EGF/EGFR signaling pathway"	"Negative regulation of MAPK pathway; Signaling by BRAF and RAF1 fusions; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants"	"9"	"0"	"201.7"	"1299.6"	"1176.6"	"127.3"	"1042.7"	"324.4"	"439.6"	"290.5"	"408.5"	"525.6"	"1169.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62495"	"Eukaryotic peptide chain release factor subunit 1 OS=Homo sapiens OX=9606 GN=ETF1 PE=1 SV=3"	"11"	"5"	"10"	"5"	"437"	"49.0"	"5.71"	"1692.64"	"10.73"	"5"	"4"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"enzyme regulator activity;translation activity;nucleic acid binding activity;other molecular function"	"Pf03463, Pf03464, Pf03465"	"2107"	"ENSG00000120705"	"ETF1"	"B2R6B4; D3DQC1; hsa:2107; P46055; P62495; Q5M7Z7; Q96CG1"	"Translation factors"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"5"	"0"	"263.4"	"588.1"	"568.3"	"257.4"	"532.1"	"310.0"	"594.4"	"440.0"	"615.4"	"861.1"	"1415.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4P3"	"Transducin beta-like protein 2 OS=Homo sapiens OX=9606 GN=TBL2 PE=1 SV=1"	"8"	"3"	"6"	"3"	"447"	"49.8"	"9.44"	"1301.69"	"10.69"	"3"	"3"	"stress response;signal transduction"	"other membranes;ER/Golgi"	"other molecular function"	"Pf00400"	"26608"	"ENSG00000106638"	"TBL2"	"hsa:26608; Q9UQE2; Q9Y4P3"	"7q11.23 copy number variation syndrome"	""	"1"	"0"	"81.9"	"146.8"	"149.7"	"69.4"	"151.3"	"82.1"	"113.8"	"82.9"	"113.7"	"185.6"	"303.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15424"	"Scaffold attachment factor B1 OS=Homo sapiens OX=9606 GN=SAFB PE=1 SV=4"	"3"	"3"	"8"	"3"	"915"	"102.6"	"5.47"	"1362.45"	"10.68"	"3"	"3"	"cell organization and biogenesis;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf02037"	"6294"	"ENSG00000160633"	"SAFB"	"A0AV56; B7Z5B6; B7ZLP6; F5H0H3; hsa:6294; O60406; Q15424; Q59HH8"	"Interleukin-1 (IL-1) structural pathway"	"SUMOylation of transcription cofactors"	"2"	"0"	"148.5"	"538.1"	"475.6"	"131.5"	"440.7"	"172.6"	"326.7"	"212.9"	"341.3"	"443.1"	"694.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13547"	"Histone deacetylase 1 OS=Homo sapiens OX=9606 GN=HDAC1 PE=1 SV=1"	"8"	"4"	"9"	"2"	"482"	"55.1"	"5.48"	"1794.87"	"10.66"	"4"	"3"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00850"	"3065"	"ENSG00000116478"	"HDAC1"	"hsa:3065; Q13547; Q92534"	"Androgen receptor signaling pathway; Energy metabolism; Cell cycle; TNF-related weak inducer of apoptosis (TWEAK) signaling pathway; Neural crest differentiation; Retinoblastoma gene in cancer; Notch signaling; Apoptosis-related network due to altered Notch3 in ovarian cancer; Initiation of transcription and translation elongation at the HIV-1 LTR; MECP2 and associated Rett syndrome; IL6 signaling pathway; Valproic acid pathway; VEGFA-VEGFR2 signaling; Ethanol effects on histone modifications; Rett syndrome causing genes; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; Ciliary landscape; Transcription co-factors SKI and SKIL protein partners; Overlap between signal transduction pathways contributing to LMNA laminopathies; Opioid receptor pathways; Notch signaling pathway; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Potential therapeutics for SARS; Estrogen-dependent gene expression; Formation of the beta-catenin:TCF transactivating complex; HDACs deacetylate histones; NoRC negatively regulates rRNA expression; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; SUMOylation of chromatin organization proteins; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes; SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Deactivation of the beta-catenin transactivating complex; Regulation of PTEN gene transcription; MECP2 regulates transcription of neuronal ligands; Factors involved in megakaryocyte development and platelet production; Downregulation of SMAD2/3:SMAD4 transcriptional activity; RNA Polymerase I Transcription Initiation; p75NTR negatively regulates cell cycle via SC1; NOTCH1 Intracellular Domain Regulates Transcription; Notch-HLH transcription pathway; Regulation of MECP2 expression and activity; STAT3 nuclear events downstream of ALK signaling; G1/S-Specific Transcription; Regulation of TP53 Activity through Acetylation; Transcription of E2F targets under negative control by DREAM complex; Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1; MECP2 regulates neuronal receptors and channels; Repression of WNT target genes; Loss of MECP2 binding ability to 5mC-DNA"	"53"	"2"	"335.2"	"614.0"	"696.2"	"287.2"	"643.0"	"419.8"	"623.8"	"404.4"	"671.0"	"700.1"	"1001.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99426"	"Tubulin-folding cofactor B OS=Homo sapiens OX=9606 GN=TBCB PE=1 SV=2"	"10"	"2"	"6"	"2"	"244"	"27.3"	"5.15"	"1313.34"	"10.65"	"2"	"2"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf01302, Pf14560"	"1155"	"ENSG00000105254"	"TBCB"	"hsa:1155; O00111; O00674; O14728; Q6FGY5; Q99426"	""	"Post-chaperonin tubulin folding pathway"	"1"	"0"	"88.5"	"378.2"	"340.3"	"69.9"	"277.0"	"103.8"	"146.6"	"100.5"	"159.5"	"203.6"	"346.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86X55"	"Histone-arginine methyltransferase CARM1 OS=Homo sapiens OX=9606 GN=CARM1 PE=1 SV=3"	"6"	"2"	"3"	"2"	"608"	"65.8"	"6.73"	"363.19"	"10.64"	"1"	"2"	"cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06325, Pf11531"	"10498"	"ENSG00000142453"	"CARM1"	"A6NN38; hsa:10498; Q86X55"	"Androgen receptor signaling pathway; Nitric oxide metabolism in cystic fibrosis"	"Estrogen-dependent gene expression; PPARA activates gene expression; RMTs methylate histone arginines; Transcriptional regulation of white adipocyte differentiation; Heme signaling; BMAL1:CLOCK,NPAS2 activates circadian gene expression; Transcriptional activation of mitochondrial biogenesis; Cytoprotection by HMOX1; Activation of gene expression by SREBF (SREBP); TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; RORA activates gene expression"	"15"	"0"	"49.7"	"89.8"	"93.6"	"44.5"	"104.6"	"62.8"	"89.7"	"73.8"	"95.7"	"123.8"	"173.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQ67"	"Glutamate-rich WD repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=GRWD1 PE=1 SV=1"	"5"	"2"	"6"	"2"	"446"	"49.4"	"4.92"	"1425.44"	"10.64"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400, Pf12265"	"83743"	"ENSG00000105447"	"GRWD1"	"A0MNN5; hsa:83743; Q8TF59; Q9BQ67"	""	""	"0"	"0"	"89.4"	"152.9"	"184.9"	"78.9"	"188.3"	"114.5"	"245.2"	"184.8"	"268.7"	"331.8"	"407.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P33991"	"DNA replication licensing factor MCM4 OS=Homo sapiens OX=9606 GN=MCM4 PE=1 SV=5"	"4"	"3"	"6"	"3"	"863"	"96.5"	"6.74"	"1014.51"	"10.60"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf14551, Pf17207, Pf17855"	"4173"	"ENSG00000104738"	"MCM4"	"hsa:4173; P33991; Q8NEH1; Q99658"	"Cell cycle; Gastric cancer network 1; Retinoblastoma gene in cancer; Ciliary landscape; G1 to S cell cycle control; DNA replication; 10q11.21q11.23 copy number variation syndrome"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"13"	"0"	"115.9"	"524.1"	"471.9"	"102.8"	"417.8"	"134.4"	"214.9"	"139.8"	"205.7"	"231.5"	"446.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23368"	"NAD-dependent malic enzyme, mitochondrial OS=Homo sapiens OX=9606 GN=ME2 PE=1 SV=1"	"7"	"3"	"7"	"3"	"584"	"65.4"	"7.61"	"995.86"	"10.59"	"2"	"3"	"other metabolic processes;other biological processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf00390, Pf03949"	"4200"	"ENSG00000082212"	"ME2"	"B2R8J2; hsa:4200; P23368; Q9BWL6; Q9BYG1; Q9H4B2"	"TCA cycle in senescence"	"Citric acid cycle (TCA cycle)"	"2"	"0"	"105.8"	"333.0"	"277.9"	"98.7"	"261.2"	"119.6"	"262.6"	"327.4"	"449.5"	"845.5"	"1569.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q02952"	"A-kinase anchor protein 12 OS=Homo sapiens OX=9606 GN=AKAP12 PE=1 SV=4"	"3"	"3"	"5"	"3"	"1782"	"191.4"	"4.41"	"801.94"	"10.56"	"2"	"3"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf03832, Pf10522"	"9590"	"ENSG00000131016"	"AKAP12"	"hsa:9590; O00310; O00498; Q02952; Q4LE68; Q5SZ80; Q5TGN1; Q68D82; Q99970"	"G protein signaling pathways"	"RHOD GTPase cycle; RHOF GTPase cycle"	"3"	"0"	"65.0"	"98.0"	"102.7"	"51.4"	"87.9"	"55.6"	"66.9"	"53.6"	"61.3"	"76.8"	"109.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14818"	"Proteasome subunit alpha type-7 OS=Homo sapiens OX=9606 GN=PSMA7 PE=1 SV=1"	"21"	"5"	"9"	"5"	"248"	"27.9"	"8.46"	"1414.69"	"10.53"	"5"	"4"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00227, Pf10584"	"5688"	"ENSG00000101182"	"PSMA7"	"B2R515; hsa:5688; O14818; Q5JXJ2; Q9BR53; Q9H4K5; Q9UEU8"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"62"	"0"	"297.8"	"711.4"	"776.7"	"263.8"	"671.2"	"316.0"	"637.4"	"551.6"	"703.7"	"1064.5"	"2003.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NFY9"	"Kelch repeat and BTB domain-containing protein 8 OS=Homo sapiens OX=9606 GN=KBTBD8 PE=1 SV=2"	"8"	"4"	"7"	"4"	"601"	"68.8"	"6.29"	"1306.87"	"10.52"	"4"	"3"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;other cell component"	""	"Pf00651, Pf01344, Pf07707"	"84541"	"ENSG00000163376"	"KBTBD8"	"B4DTW6; hsa:84541; Q8NFY9; Q96JI5"	""	"Antigen processing: Ubiquitination & Proteasome degradation; Neddylation"	"2"	"0"	"67.2"	"142.1"	"154.2"	"67.5"	"194.8"	"87.5"	"141.9"	"155.0"	"220.8"	"341.4"	"391.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P33993"	"DNA replication licensing factor MCM7 OS=Homo sapiens OX=9606 GN=MCM7 PE=1 SV=4"	"6"	"3"	"6"	"3"	"719"	"81.3"	"6.46"	"1188.18"	"10.50"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf14551, Pf17207, Pf17855"	"4176"	"ENSG00000166508"	"MCM7"	"A4D2A1; A4D2A2; E9PGN9; hsa:4176; P33993; Q15076; Q96D34; Q96GL1"	"miRNA regulation of DNA damage response; Cell cycle; Retinoblastoma gene in cancer; Ciliary landscape; G1 to S cell cycle control; DNA replication; 10q11.21q11.23 copy number variation syndrome"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"13"	"0"	"83.1"	"295.4"	"235.8"	"74.3"	"235.1"	"88.1"	"241.6"	"213.4"	"286.7"	"395.6"	"631.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43148"	"mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1"	"9"	"4"	"8"	"4"	"476"	"54.8"	"6.61"	"1210.42"	"10.49"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03291"	"8731"	"ENSG00000101654"	"RNMT"	"B0YJ90; D3DUJ5; hsa:8731; O43148; O94996; Q9UIJ9"	"mRNA processing"	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE"	"4"	"0"	"113.2"	"254.0"	"242.3"	"105.2"	"226.5"	"105.3"	"260.1"	"220.9"	"311.0"	"343.6"	"499.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49006"	"MARCKS-related protein OS=Homo sapiens OX=9606 GN=MARCKSL1 PE=1 SV=2"	"10"	"2"	"7"	"2"	"195"	"19.5"	"4.67"	"1207.36"	"10.41"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02063"	"65108"	"ENSG00000175130"	"MARCKSL1"	"D3DPQ0; hsa:65108; P49006; Q5TEE6; Q6NXS5"	""	""	"0"	"0"	"183.4"	"1239.6"	"959.7"	"113.8"	"806.8"	"260.1"	"456.0"	"298.6"	"512.9"	"633.5"	"1361.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q02809"	"Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 OS=Homo sapiens OX=9606 GN=PLOD1 PE=1 SV=2"	"5"	"3"	"5"	"3"	"727"	"83.5"	"6.95"	"763.93"	"10.37"	"2"	"3"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf03171"	"5351"	"ENSG00000083444"	"PLOD1"	"B4DR87; hsa:5351; Q02809; Q96AV9; Q9H132"	"Type I collagen synthesis in the context of osteogenesis imperfecta"	"Collagen biosynthesis and modifying enzymes"	"2"	"0"	"76.4"	"157.1"	"191.4"	"66.9"	"154.9"	"83.6"	"152.0"	"112.2"	"150.1"	"223.5"	"285.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60885"	"Bromodomain-containing protein 4 OS=Homo sapiens OX=9606 GN=BRD4 PE=1 SV=2"	"3"	"4"	"6"	"4"	"1362"	"152.1"	"9.19"	"745.00"	"10.31"	"2"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00439, Pf17035, Pf17105"	"23476"	"ENSG00000141867"	"BRD4"	"hsa:23476; O60433; O60885; Q4G0X8; Q86YS8; Q96PD3"	"VEGFA-VEGFR2 signaling; 7q11.23 copy number variation syndrome"	"Potential therapeutics for SARS"	"3"	"0"	"292.7"	"405.6"	"416.7"	"250.2"	"535.2"	"311.2"	"590.0"	"405.5"	"576.1"	"637.6"	"736.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P41567"	"Eukaryotic translation initiation factor 1 OS=Homo sapiens OX=9606 GN=EIF1 PE=1 SV=1"	"16"	"2"	"6"	"2"	"113"	"12.7"	"7.44"	"1186.52"	"10.29"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf01253"	"10209"	"ENSG00000173812"	"EIF1"	"hsa:10209; P41567; Q9UNQ9"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	""	"2"	"0"	"33.6"	"75.0"	"77.1"	"33.0"	"75.1"	"39.3"	"55.7"	"58.3"	"87.9"	"168.6"	"357.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9C005"	"Protein dpy-30 homolog OS=Homo sapiens OX=9606 GN=DPY30 PE=1 SV=1"	"22"	"2"	"6"	"2"	"99"	"11.2"	"4.88"	"1066.69"	"10.28"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport"	"ER/Golgi;nucleus"	"other molecular function"	"Pf05186"	"84661"	"ENSG00000162961"	"DPY30"	"D6W578; hsa:84661; Q9C005"	"Kleefstra syndrome"	"Activation of anterior HOX genes in hindbrain development during early embryogenesis; PKMTs methylate histone lysines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Formation of WDR5-containing histone-modifying complexes"	"5"	"0"	"246.2"	"511.8"	"508.1"	"189.8"	"511.1"	"245.8"	"485.3"	"349.0"	"483.6"	"603.3"	"864.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60568"	"Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 OS=Homo sapiens OX=9606 GN=PLOD3 PE=1 SV=1"	"7"	"3"	"6"	"3"	"738"	"84.7"	"6.05"	"1006.40"	"10.24"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"non-structural extracellular;extracellular matrix;other membranes;ER/Golgi"	"other molecular function"	"Pf03171"	"8985"	"ENSG00000106397"	"PLOD3"	"B2R6W6; hsa:8985; O60568; Q540C3"	"VEGFA-VEGFR2 signaling; IL-18 signaling pathway"	"Collagen biosynthesis and modifying enzymes"	"3"	"0"	"30.6"	"101.3"	"89.7"	"30.0"	"93.0"	"41.7"	"84.7"	"63.4"	"92.2"	"132.1"	"188.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15126"	"Phosphomevalonate kinase OS=Homo sapiens OX=9606 GN=PMVK PE=1 SV=3"	"27"	"5"	"9"	"5"	"192"	"22.0"	"5.73"	"1592.61"	"10.23"	"5"	"4"	"other metabolic processes;other biological processes"	"cytosol;other cytoplasmic organelle"	"kinase activity;other molecular function"	"Pf04275"	"10654"	"ENSG00000163344"	"PMVK"	"hsa:10654; Q15126; Q5TZW9"	"Cholesterol biosynthesis pathway; Mevalonate pathway; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Cholesterol synthesis disorders; Cholesterol metabolism; Enterocyte cholesterol metabolism"	"Activation of gene expression by SREBF (SREBP); Cholesterol biosynthesis"	"8"	"0"	"91.8"	"330.3"	"288.1"	"91.2"	"386.3"	"283.8"	"642.1"	"929.2"	"985.0"	"664.4"	"1214.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5JSH3"	"WD repeat-containing protein 44 OS=Homo sapiens OX=9606 GN=WDR44 PE=1 SV=1"	"5"	"5"	"7"	"5"	"913"	"101.3"	"5.45"	"1151.99"	"10.19"	"3"	"4"	""	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf00400"	"54521"	"ENSG00000131725"	"WDR44"	"B4DSE9; F8W913; hsa:54521; Q0JS52; Q0JTF3; Q5JSH2; Q5JSH3; Q6ZSC1; Q7Z365; Q7Z3P6; Q8NAU8; Q8NHU5; Q9NUV4"	"Ectoderm differentiation"	""	"1"	"0"	"103.4"	"242.0"	"243.5"	"111.9"	"243.1"	"126.6"	"348.8"	"443.7"	"698.4"	"1031.6"	"1627.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25789"	"Proteasome subunit alpha type-4 OS=Homo sapiens OX=9606 GN=PSMA4 PE=1 SV=1"	"13"	"4"	"8"	"4"	"261"	"29.5"	"7.72"	"1189.13"	"10.17"	"4"	"4"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf00227, Pf10584"	"5685"	"ENSG00000041357"	"PSMA4"	"D3DW86; hsa:5685; P25789; Q53XP2; Q567Q5; Q8TBD1"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Exercise-induced circadian regulation; Alzheimer's disease"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"63"	"0"	"328.6"	"682.5"	"1017.8"	"293.4"	"657.2"	"434.7"	"610.4"	"408.5"	"562.4"	"748.9"	"1327.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13283"	"Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1"	"9"	"3"	"4"	"3"	"466"	"52.1"	"5.52"	"285.17"	"10.15"	"1"	"3"	"cell organization and biogenesis;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00076, Pf02136"	"10146"	"ENSG00000145907"	"G3BP1"	"hsa:10146; Q13283; Q5HYE9"	""	"SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"1"	"0"	"58.6"	"180.1"	"162.4"	"62.2"	"179.0"	"69.6"	"311.8"	"231.0"	"329.6"	"443.4"	"552.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P1U1"	"Actin-related protein 3B OS=Homo sapiens OX=9606 GN=ACTR3B PE=2 SV=1"	"10"	"3"	"5"	"1"	"418"	"47.6"	"5.88"	"614.89"	"10.15"	"2"	"3"	""	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00022"	"57180"	"ENSG00000133627"	"ACTR3B"	"A8MTG1; B4DFW4; hsa:57180; Q7Z526; Q96BT2; Q9P1U1"	""	""	"0"	"0"	"15.8"	"41.4"	"31.5"	"13.7"	"31.6"	"15.6"	"42.2"	"29.8"	"44.3"	"70.9"	"108.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P67936"	"Tropomyosin alpha-4 chain OS=Homo sapiens OX=9606 GN=TPM4 PE=1 SV=3"	"15"	"5"	"9"	"1"	"248"	"28.5"	"4.69"	"1167.28"	"10.11"	"4"	"5"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton"	"cytoskeletal activity;other molecular function"	"Pf00261"	"7171"	"ENSG00000167460"	"TPM4"	"hsa:7171; P07226; P67936; Q15659; Q5U0D9; Q9BU85; Q9H8Q3; Q9UCS1; Q9UCS2; Q9UCS3; Q9UCS4"	"Striated muscle contraction pathway"	"RHOV GTPase cycle; Signaling by ALK fusions and activated point mutants; Smooth Muscle Contraction; Striated Muscle Contraction"	"5"	"0"	"34.6"	"99.0"	"86.7"	"28.8"	"96.3"	"39.4"	"73.9"	"54.6"	"91.2"	"99.9"	"149.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WU79"	"Stromal membrane-associated protein 2 OS=Homo sapiens OX=9606 GN=SMAP2 PE=1 SV=1"	"16"	"4"	"6"	"4"	"429"	"46.8"	"8.87"	"923.22"	"10.11"	"3"	"3"	""	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf01412"	"64744"	"ENSG00000084070"	"SMAP2"	"B2R7T1; B7Z5B5; B7Z8V2; D3DPV2; hsa:64744; Q5QPL2; Q8WU79; Q96C93; Q9NST2; Q9UJL8"	""	""	"0"	"0"	"107.2"	"137.2"	"145.9"	"91.8"	"186.8"	"100.8"	"194.1"	"164.3"	"224.3"	"252.5"	"334.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09936"	"Ubiquitin carboxyl-terminal hydrolase isozyme L1 OS=Homo sapiens OX=9606 GN=UCHL1 PE=1 SV=2"	"16"	"3"	"7"	"3"	"223"	"24.8"	"5.48"	"832.38"	"10.11"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01088"	"7345"	"ENSG00000154277"	"UCHL1"	"hsa:7345; P09936; Q4W5K6; Q71UM0"	"Proteasome degradation; Parkinson's disease pathway; Hepatitis C and hepatocellular carcinoma"	"UCH proteinases"	"4"	"0"	"110.1"	"352.5"	"308.2"	"72.2"	"348.0"	"142.5"	"225.6"	"140.9"	"198.5"	"235.0"	"319.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07711"	"Cathepsin L1 OS=Homo sapiens OX=9606 GN=CTSL PE=1 SV=2"	"11"	"2"	"3"	"2"	"333"	"37.5"	"5.45"	"329.71"	"10.09"	"1"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00112, Pf08246"	"1514"	"ENSG00000135047"	"CTSL"	"hsa:1514; P07711; Q6IAV1; Q96QJ0"	"Primary focal segmental glomerulosclerosis (FSGS); Ebola virus infection in host; Mitochondrial immune response to SARS-CoV-2"	"MHC class II antigen presentation; Collagen degradation; Assembly of collagen fibrils and other multimeric structures; Attachment and Entry; RUNX1 regulates transcription of genes involved in differentiation of keratinocytes; Attachment and Entry; Trafficking and processing of endosomal TLR; Endosomal/Vacuolar pathway"	"12"	"0"	"34.0"	"84.1"	"76.5"	"32.7"	"85.8"	"46.4"	"67.5"	"65.5"	"121.2"	"200.1"	"400.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y224"	"RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1"	"17"	"4"	"8"	"4"	"244"	"28.1"	"6.65"	"1300.83"	"10.07"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf10036"	"51637"	"ENSG00000087302"	"RTRAF"	"hsa:51637; Q9Y224"	""	"tRNA processing in the nucleus"	"1"	"0"	"238.4"	"518.9"	"570.4"	"196.6"	"443.0"	"290.5"	"738.8"	"499.3"	"744.1"	"957.9"	"1489.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WU90"	"Zinc finger CCCH domain-containing protein 15 OS=Homo sapiens OX=9606 GN=ZC3H15 PE=1 SV=1"	"9"	"3"	"5"	"3"	"426"	"48.6"	"5.31"	"844.00"	"10.06"	"2"	"3"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00642, Pf16543"	"55854"	"ENSG00000065548"	"ZC3H15"	"B4DMW2; D3DPG7; hsa:55854; Q5QTQ4; Q8WU90; Q8WZ06; Q9NUZ3; Q9NZ37; Q9P079"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"88.8"	"175.7"	"212.0"	"82.9"	"198.7"	"100.0"	"225.6"	"143.4"	"251.4"	"287.6"	"368.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P0K7"	"Ankycorbin OS=Homo sapiens OX=9606 GN=RAI14 PE=1 SV=2"	"4"	"4"	"6"	"3"	"980"	"110.0"	"6.21"	"1098.39"	"10.05"	"3"	"3"	"other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf00023, Pf12796"	"26064"	"ENSG00000039560"	"RAI14"	"E9PED3; hsa:26064; Q6V1W9; Q7Z5I4; Q7Z733; Q9P0K7; Q9P2L2; Q9Y3T5"	""	""	"0"	"0"	"52.6"	"165.6"	"160.4"	"73.8"	"150.5"	"79.6"	"120.3"	"96.0"	"144.2"	"196.1"	"304.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14247"	"Src substrate cortactin OS=Homo sapiens OX=9606 GN=CTTN PE=1 SV=2"	"7"	"3"	"6"	"3"	"550"	"61.5"	"5.40"	"1169.25"	"10.02"	"3"	"3"	"cell adhesion;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf02218, Pf14604"	"2017"	"ENSG00000085733; ENSG00000288401"	"CTTN"	"hsa:2017; Q14247; Q8N707; Q96H99"	"Pathogenic Escherichia coli infection; Hepatitis C and hepatocellular carcinoma"	"Clathrin-mediated endocytosis; RHO GTPases activate PAKs"	"4"	"0"	"330.6"	"572.2"	"566.7"	"231.6"	"567.2"	"325.2"	"426.2"	"310.6"	"503.6"	"570.3"	"762.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13995"	"Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD2 PE=1 SV=2"	"13"	"3"	"5"	"3"	"350"	"37.9"	"8.73"	"793.03"	"10.01"	"2"	"3"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00763, Pf02882"	"10797"	"ENSG00000065911"	"MTHFD2"	"hsa:10797; P13995; Q53G90; Q53GV5; Q53S36; Q7Z650"	"Folate metabolism; One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways"	"Metabolism of folate and pterines"	"4"	"0"	"158.3"	"424.1"	"401.0"	"160.2"	"359.6"	"170.1"	"326.1"	"278.1"	"360.3"	"438.3"	"665.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60841"	"Eukaryotic translation initiation factor 5B OS=Homo sapiens OX=9606 GN=EIF5B PE=1 SV=4"	"5"	"4"	"7"	"4"	"1220"	"138.7"	"5.49"	"1537.96"	"9.94"	"4"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03144, Pf11987"	"9669"	"ENSG00000158417"	"EIF5B"	"hsa:9669; O60841; O95805; Q53RV7; Q53SI8; Q9UF81; Q9UMN7"	"Translation factors; Ciliary landscape"	"GTP hydrolysis and joining of the 60S ribosomal subunit"	"3"	"0"	"60.6"	"110.0"	"135.1"	"76.6"	"129.5"	"68.3"	"184.7"	"130.2"	"197.5"	"264.2"	"366.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01085"	"Nucleolysin TIAR OS=Homo sapiens OX=9606 GN=TIAL1 PE=1 SV=1"	"8"	"3"	"6"	"2"	"375"	"41.6"	"7.74"	"1073.39"	"9.92"	"3"	"3"	"cell cycle OR cell proliferation;stress response;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"7073"	"ENSG00000151923"	"TIAL1"	"A8K3T0; A8K4L9; hsa:7073; Q01085"	""	"FGFR2 alternative splicing"	"1"	"1"	"175.1"	"346.1"	"336.5"	"158.2"	"353.0"	"200.5"	"341.7"	"264.2"	"370.5"	"593.3"	"647.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62244"	"40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2"	"32"	"5"	"11"	"5"	"130"	"14.8"	"10.13"	"1957.80"	"9.91"	"5"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00410"	"6210"	"ENSG00000134419"	"RPS15A"	"hsa:6210; P39027; P39031; P62244; Q3MHD9; Q8C023; Q9BV24"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Response of EIF2AK4 (GCN2) to amino acid deficiency; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"510.1"	"1189.1"	"1162.1"	"503.5"	"1113.5"	"545.8"	"859.0"	"713.2"	"916.6"	"1328.5"	"2037.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95819"	"Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens OX=9606 GN=MAP4K4 PE=1 SV=2"	"4"	"2"	"4"	"1"	"1239"	"142.0"	"7.46"	"235.85"	"9.90"	"1"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"other cell component"	"cytoskeletal activity;kinase activity;other molecular function"	"Pf00069, Pf00780"	"9448"	"ENSG00000071054"	"MAP4K4"	"E7ESS2; hsa:9448; O75172; O95819; Q9NST7"	"MAPK signaling pathway; Angiopoietin-like protein 8 regulatory pathway; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-YAP signaling; Insulin signaling; Pleural mesothelioma"	"Oxidative Stress Induced Senescence"	"7"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UDY4"	"DnaJ homolog subfamily B member 4 OS=Homo sapiens OX=9606 GN=DNAJB4 PE=1 SV=1"	"9"	"2"	"5"	"1"	"337"	"37.8"	"8.50"	"714.95"	"9.88"	"2"	"2"	"stress response;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus"	"other molecular function"	"Pf00226, Pf01556"	"11080"	"ENSG00000162616"	"DNAJB4"	"B2R824; hsa:11080; Q13431; Q9UDY4"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"2.3"	"9.7"	"9.0"	"0.0"	"5.3"	"2.4"	"15.7"	"12.6"	"19.7"	"38.4"	"45.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P48444"	"Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1"	"7"	"4"	"6"	"4"	"511"	"57.2"	"6.21"	"1236.70"	"9.88"	"3"	"3"	"transport;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi"	""	"Pf00928, Pf01217"	"372"	"ENSG00000095139"	"ARCN1"	"B4E1X2; E9PEU4; hsa:372; P48444; Q52M80"	"miR-517 relationship with ARCN1 and USP1"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport"	"3"	"0"	"165.6"	"401.5"	"366.5"	"104.8"	"306.6"	"156.7"	"303.2"	"246.3"	"317.7"	"377.6"	"681.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P17174"	"Aspartate aminotransferase, cytoplasmic OS=Homo sapiens OX=9606 GN=GOT1 PE=1 SV=3"	"9"	"2"	"3"	"2"	"413"	"46.2"	"7.01"	"666.96"	"9.87"	"1"	"2"	"other metabolic processes;signal transduction;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00155"	"2805"	"ENSG00000120053"	"GOT1"	"B2R6R7; B7Z7E9; hsa:2805; P17174; Q5VW80"	"Alanine and aspartate metabolism; Trans-sulfuration pathway; Amino acid metabolism; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; TCA cycle in senescence; Neuroinflammation and glutamatergic signaling; Glycolysis and gluconeogenesis"	"Gluconeogenesis; Aspartate and asparagine metabolism; Methionine salvage pathway"	"10"	"0"	"6.1"	"49.0"	"38.0"	"4.1"	"41.4"	"8.5"	"13.3"	"11.4"	"9.8"	"16.7"	"29.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14166"	"Tubulin--tyrosine ligase-like protein 12 OS=Homo sapiens OX=9606 GN=TTLL12 PE=1 SV=2"	"6"	"3"	"5"	"3"	"644"	"74.4"	"5.53"	"631.66"	"9.85"	"2"	"3"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03133"	"23170"	"ENSG00000100304"	"TTLL12"	"hsa:23170; Q14166; Q20WK5; Q9UGU3"	""	"Carboxyterminal post-translational modifications of tubulin"	"1"	"0"	"104.3"	"271.3"	"238.5"	"82.6"	"263.2"	"91.4"	"185.5"	"145.1"	"197.9"	"258.0"	"380.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13526"	"Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 OS=Homo sapiens OX=9606 GN=PIN1 PE=1 SV=1"	"23"	"3"	"6"	"3"	"163"	"18.2"	"8.82"	"1271.85"	"9.85"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00397, Pf00639"	"5300"	"ENSG00000127445"	"PIN1"	"A8K4V9; hsa:5300; Q13526; Q53X75"	"Novel intracellular components of RIG-I-like receptor pathway"	"Regulation of TP53 Activity through Phosphorylation; ISG15 antiviral mechanism; Negative regulators of DDX58/IFIH1 signaling; PI5P Regulates TP53 Acetylation; RHO GTPases Activate NADPH Oxidases"	"6"	"0"	"104.7"	"272.6"	"278.5"	"96.6"	"271.6"	"104.1"	"210.5"	"181.5"	"224.1"	"324.0"	"522.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43314"	"Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 OS=Homo sapiens OX=9606 GN=PPIP5K2 PE=1 SV=3"	"3"	"3"	"4"	"3"	"1243"	"140.3"	"8.22"	"331.94"	"9.84"	"1"	"3"	"other metabolic processes;other biological processes"	"cytosol"	"kinase activity;other molecular function"	"Pf00328, Pf18086"	"23262"	"ENSG00000145725"	"PPIP5K2"	"A1NI53; A6NGS8; hsa:23262; O43314; Q8TB50"	""	"Synthesis of pyrophosphates in the cytosol"	"1"	"0"	"69.2"	"129.7"	"117.8"	"60.7"	"120.2"	"72.3"	"309.5"	"260.3"	"360.7"	"495.9"	"711.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IY18"	"Structural maintenance of chromosomes protein 5 OS=Homo sapiens OX=9606 GN=SMC5 PE=1 SV=2"	"5"	"4"	"7"	"4"	"1101"	"128.7"	"8.38"	"1195.00"	"9.75"	"4"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02463"	"23137"	"ENSG00000198887"	"SMC5"	"A6NM81; hsa:23137; O60335; Q05D92; Q5VZ60; Q8IY18; Q96SB9"	""	"SUMOylation of DNA damage response and repair proteins"	"1"	"0"	"36.1"	"76.6"	"84.3"	"33.9"	"74.2"	"47.9"	"100.1"	"75.9"	"118.0"	"159.5"	"235.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y383"	"Putative RNA-binding protein Luc7-like 2 OS=Homo sapiens OX=9606 GN=LUC7L2 PE=1 SV=2"	"8"	"3"	"6"	"3"	"392"	"46.5"	"10.01"	"1147.38"	"9.72"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03194"	"51631"	"ENSG00000146963"	"LUC7L2"	"B7Z500; hsa:51631; Q8IUP9; Q9NVL3; Q9NVN7; Q9UQN1; Q9Y383"	""	""	"0"	"0"	"102.3"	"327.7"	"291.8"	"108.3"	"304.6"	"150.5"	"379.0"	"271.5"	"411.7"	"510.5"	"869.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P24666"	"Low molecular weight phosphotyrosine protein phosphatase OS=Homo sapiens OX=9606 GN=ACP1 PE=1 SV=3"	"14"	"3"	"7"	"3"	"158"	"18.0"	"6.74"	"1473.88"	"9.67"	"3"	"3"	"protein metabolism;other metabolic processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf01451"	"52"	"ENSG00000143727"	"ACP1"	"A8K1L9; B5MCC7; hsa:52; P24666; P24667; Q16035; Q16036; Q16725; Q3KQX8; Q53RU0"	"VEGFA-VEGFR2 signaling; 11p11.2 copy number variation syndrome"	""	"2"	"0"	"49.3"	"175.2"	"160.2"	"46.5"	"141.2"	"76.8"	"107.3"	"89.7"	"120.5"	"140.3"	"203.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15347"	"High mobility group protein B3 OS=Homo sapiens OX=9606 GN=HMGB3 PE=1 SV=4"	"28"	"6"	"9"	"5"	"200"	"23.0"	"8.37"	"2276.30"	"9.66"	"6"	"3"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00505, Pf09011"	"3149"	"ENSG00000029993"	"HMGB3"	"hsa:3149; O15347; O95556; Q6NS40"	""	""	"0"	"1"	"129.3"	"226.4"	"299.9"	"134.9"	"276.3"	"165.6"	"1099.2"	"725.7"	"1199.0"	"1534.9"	"2555.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9C0C2"	"182 kDa tankyrase-1-binding protein OS=Homo sapiens OX=9606 GN=TNKS1BP1 PE=1 SV=4"	"3"	"4"	"7"	"4"	"1729"	"181.7"	"4.86"	"1545.99"	"9.65"	"4"	"3"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf15327"	"85456"	"ENSG00000149115"	"TNKS1BP1"	"A7E2F8; hsa:85456; Q6PJ35; Q6ZV74; Q9C0C2"	"Ciliary landscape"	"Deadenylation of mRNA; TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"	"3"	"0"	"68.3"	"151.7"	"147.3"	"52.7"	"139.6"	"73.7"	"144.1"	"140.0"	"193.0"	"237.2"	"281.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15435"	"Protein phosphatase 1 regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PPP1R7 PE=1 SV=1"	"10"	"3"	"7"	"3"	"360"	"41.5"	"4.91"	"1436.62"	"9.63"	"3"	"3"	"other biological processes"	"other cell component"	"enzyme regulator activity"	"Pf14580"	"5510"	"ENSG00000115685"	"PPP1R7"	"B4DFD4; B5MCY6; hsa:5510; Q15435; Q9UQE5; Q9UQE6; Q9Y6K4"	"2q37 copy number variation syndrome"	""	"1"	"0"	"31.3"	"247.6"	"176.0"	"25.3"	"155.3"	"47.9"	"72.2"	"71.9"	"120.4"	"311.2"	"890.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49916"	"DNA ligase 3 OS=Homo sapiens OX=9606 GN=LIG3 PE=1 SV=2"	"3"	"3"	"5"	"3"	"1009"	"112.8"	"9.01"	"787.67"	"9.55"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00645, Pf01068, Pf04675, Pf04679, Pf16759"	"3980"	"ENSG00000005156"	"LIG3"	"E5KLB5; E5KLB6; hsa:3980; P49916; Q16714; Q6NVK3"	"Base excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; 17q12 copy number variation syndrome"	"Gap-filling DNA repair synthesis and ligation in TC-NER; Gap-filling DNA repair synthesis and ligation in GG-NER; APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway; HDR through MMEJ (alt-NHEJ); Resolution of AP sites via the single-nucleotide replacement pathway"	"9"	"0"	"90.8"	"212.0"	"186.6"	"83.1"	"172.8"	"94.5"	"223.7"	"182.4"	"268.5"	"402.6"	"750.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99459"	"Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2"	"8"	"5"	"8"	"5"	"802"	"92.2"	"8.18"	"1885.99"	"9.54"	"5"	"3"	"cell cycle OR cell proliferation;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf11831, Pf13921"	"988"	"ENSG00000096401"	"CDC5L"	"hsa:988; Q76N46; Q99459; Q99974"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"147.9"	"290.2"	"315.6"	"128.0"	"303.7"	"314.1"	"369.2"	"401.6"	"451.0"	"754.3"	"752.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61026"	"Ras-related protein Rab-10 OS=Homo sapiens OX=9606 GN=RAB10 PE=1 SV=1"	"17"	"3"	"6"	"2"	"200"	"22.5"	"8.38"	"1211.77"	"9.54"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00071"	"10890"	"ENSG00000084733"	"RAB10"	"D6W538; hsa:10890; O88386; P61026; Q6IA52; Q9D7X6; Q9H0T3"	"Focal adhesion: PI3K-Akt-mTOR-signaling pathway"	"RAB GEFs exchange GTP for GDP on RABs; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Neutrophil degranulation; RAB geranylgeranylation"	"5"	"0"	"22.1"	"116.4"	"91.4"	"13.6"	"81.6"	"26.9"	"48.0"	"40.0"	"52.3"	"68.2"	"103.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P98082"	"Disabled homolog 2 OS=Homo sapiens OX=9606 GN=DAB2 PE=1 SV=3"	"4"	"3"	"6"	"3"	"770"	"82.4"	"5.53"	"846.63"	"9.50"	"3"	"3"	"cell-cell signaling;cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00640"	"1601"	"ENSG00000153071"	"DAB2"	"A6NES5; hsa:1601; P98082; Q13598; Q9BTY0; Q9UK04"	"Endoderm differentiation"	"Cargo recognition for clathrin-mediated endocytosis; Formation of annular gap junctions"	"5"	"0"	"67.7"	"142.1"	"145.6"	"66.9"	"140.1"	"92.8"	"156.8"	"160.9"	"289.5"	"488.4"	"701.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60832"	"H/ACA ribonucleoprotein complex subunit DKC1 OS=Homo sapiens OX=9606 GN=DKC1 PE=1 SV=3"	"6"	"2"	"6"	"2"	"514"	"57.6"	"9.42"	"1065.27"	"9.49"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01472, Pf01509, Pf08068, Pf16198"	"1736"	"ENSG00000130826"	"DKC1"	"F5BSB3; hsa:1736; O43845; O60832; Q96G67; Q9Y505"	""	"rRNA modification in the nucleus and cytosol; Telomere Extension By Telomerase"	"2"	"0"	"12.3"	"29.1"	"37.4"	"16.6"	"35.3"	"13.7"	"35.1"	"31.8"	"46.3"	"66.0"	"88.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WWK9"	"Cytoskeleton-associated protein 2 OS=Homo sapiens OX=9606 GN=CKAP2 PE=1 SV=1"	"6"	"6"	"9"	"6"	"683"	"76.9"	"9.41"	"1846.36"	"9.48"	"6"	"3"	"cell cycle OR cell proliferation;other biological processes"	"cytoskeleton;other cell component"	""	"Pf15297"	"26586"	"ENSG00000136108"	"CKAP2"	"A2BDE0; A5YM58; B4DR35; E9PD90; hsa:26586; Q3KRA5; Q5VXB4; Q8IWV5; Q8IWV6; Q8WWK9; Q96FH9; Q9H012; Q9H0D0; Q9H988; Q9HC49; Q9NVG4"	""	""	"0"	"0"	"301.9"	"436.0"	"430.6"	"250.1"	"472.0"	"255.1"	"1568.1"	"1273.3"	"1570.7"	"1830.3"	"2215.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43427"	"Acidic fibroblast growth factor intracellular-binding protein OS=Homo sapiens OX=9606 GN=FIBP PE=1 SV=3"	"14"	"5"	"9"	"5"	"364"	"41.9"	"6.48"	"1435.78"	"9.48"	"5"	"4"	"signal transduction"	"other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf05427"	"9158"	"ENSG00000172500"	"FIBP"	"A8K0J7; hsa:9158; O43427; Q27Q85; Q6IBQ3; Q9HD65"	"Modulators of TCR signaling and T cell activation"	""	"1"	"0"	"95.3"	"229.5"	"240.1"	"110.4"	"262.6"	"129.5"	"291.5"	"355.9"	"689.8"	"1161.4"	"1843.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52815"	"39S ribosomal protein L12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL12 PE=1 SV=2"	"18"	"3"	"4"	"3"	"198"	"21.3"	"8.87"	"391.68"	"9.47"	"1"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00542, Pf16320"	"6182"	"ENSG00000262814"	"MRPL12"	"hsa:6182; P52815; Q969U0; Q9HCA2; Q9UQJ3"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"11.9"	"34.8"	"40.6"	"14.4"	"30.9"	"15.2"	"23.0"	"19.8"	"27.6"	"39.7"	"56.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14CX7"	"N-alpha-acetyltransferase 25, NatB auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA25 PE=1 SV=1"	"5"	"3"	"5"	"3"	"972"	"112.2"	"6.64"	"655.80"	"9.40"	"2"	"3"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;other cell component"	""	"Pf09797"	"80018"	"ENSG00000111300"	"NAA25"	"A0JLU7; hsa:80018; Q14CX7; Q6MZH1; Q7Z4N6; Q9H911"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49915"	"GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1"	"8"	"3"	"6"	"3"	"693"	"76.7"	"6.87"	"1143.45"	"9.35"	"3"	"3"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf00117, Pf00958, Pf02540"	"8833"	"ENSG00000163655"	"GMPS"	"A8K639; B4DXV7; F8W720; hsa:8833; P49915"	""	"Purine ribonucleoside monophosphate biosynthesis; Azathioprine ADME"	"2"	"0"	"13.0"	"77.2"	"62.1"	"11.6"	"51.2"	"25.9"	"18.2"	"13.2"	"18.2"	"25.5"	"57.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P78356"	"Phosphatidylinositol 5-phosphate 4-kinase type-2 beta OS=Homo sapiens OX=9606 GN=PIP4K2B PE=1 SV=1"	"12"	"3"	"6"	"2"	"416"	"47.3"	"7.33"	"1098.07"	"9.34"	"3"	"3"	"cell organization and biogenesis;other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle"	"kinase activity;other molecular function"	"Pf01504"	"8396"	"ENSG00000276293; ENSG00000277292"	"PIP4K2B"	"hsa:8396; P78356; Q5U0E8; Q8TBP2"	"Regulation of actin cytoskeleton; 17q12 copy number variation syndrome"	"Synthesis of PIPs at the plasma membrane; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; PI5P Regulates TP53 Acetylation; Synthesis of PIPs in the nucleus"	"6"	"1"	"38.8"	"77.6"	"141.8"	"34.8"	"98.9"	"44.7"	"88.4"	"99.8"	"211.0"	"319.6"	"591.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TAE8"	"Growth arrest and DNA damage-inducible proteins-interacting protein 1 OS=Homo sapiens OX=9606 GN=GADD45GIP1 PE=1 SV=1"	"14"	"2"	"6"	"2"	"222"	"25.4"	"10.02"	"918.00"	"9.33"	"2"	"2"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	""	"Pf10147"	"90480"	"ENSG00000179271"	"GADD45GIP1"	"hsa:90480; Q8IVM3; Q8TAE8; Q8TE51; Q969P9; Q9BSM6"	""	"Mitochondrial translation elongation; Mitochondrial translation initiation; Mitochondrial translation termination"	"3"	"0"	"35.0"	"79.8"	"106.1"	"44.5"	"80.2"	"38.5"	"89.9"	"73.8"	"129.2"	"217.8"	"289.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61163"	"Alpha-centractin OS=Homo sapiens OX=9606 GN=ACTR1A PE=1 SV=1"	"11"	"3"	"5"	"3"	"376"	"42.6"	"6.64"	"778.18"	"9.33"	"2"	"3"	"transport"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00022"	"10121"	"ENSG00000138107"	"ACTR1A"	"B2R6B0; hsa:10121; P42024; P61163"	""	"COPI-mediated anterograde transport; MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-independent Golgi-to-ER retrograde traffic; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"11"	"0"	"182.7"	"438.6"	"391.1"	"149.7"	"367.3"	"214.4"	"266.6"	"186.2"	"301.9"	"339.1"	"618.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BXC9"	"Bardet-Biedl syndrome 2 protein OS=Homo sapiens OX=9606 GN=BBS2 PE=1 SV=1"	"4"	"3"	"6"	"3"	"721"	"79.8"	"6.15"	"1143.16"	"9.33"	"3"	"3"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"44.0"	"103.1"	"113.7"	"45.5"	"106.2"	"61.3"	"133.5"	"174.4"	"390.7"	"638.2"	"941.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22570"	"NADPH:adrenodoxin oxidoreductase, mitochondrial OS=Homo sapiens OX=9606 GN=FDXR PE=1 SV=3"	"10"	"3"	"4"	"3"	"491"	"53.8"	"8.44"	"367.09"	"9.31"	"1"	"3"	"other metabolic processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf07992"	"2232"	"ENSG00000161513"	"FDXR"	"B4DDI7; B4DHX5; B4DQQ4; B4DX24; B7Z7G2; E7EQC1; hsa:2232; P22570; Q13716; Q4PJI0; Q9BU12"	"Iron-sulfur cluster biogenesis"	"Endogenous sterols; Pregnenolone biosynthesis; Defective CYP11A1 causes AICSR; Electron transport from NADPH to Ferredoxin"	"5"	"0"	"60.2"	"123.7"	"132.2"	"43.7"	"127.6"	"65.1"	"98.7"	"88.7"	"151.6"	"272.2"	"763.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51572"	"B-cell receptor-associated protein 31 OS=Homo sapiens OX=9606 GN=BCAP31 PE=1 SV=3"	"15"	"4"	"7"	"4"	"246"	"28.0"	"8.44"	"1548.89"	"9.30"	"4"	"3"	"cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf05529, Pf18035"	"10134"	"ENSG00000185825"	"BCAP31"	"B3KQ79; D3DWV5; hsa:10134; P51572; Q13836; Q96CF0"	""	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC; RHOA GTPase cycle; Apoptotic cleavage of cellular proteins"	"4"	"0"	"409.6"	"1117.8"	"1059.8"	"336.8"	"939.8"	"445.1"	"690.3"	"531.8"	"852.0"	"1139.5"	"1812.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NYL9"	"Tropomodulin-3 OS=Homo sapiens OX=9606 GN=TMOD3 PE=1 SV=1"	"9"	"2"	"4"	"2"	"352"	"39.6"	"5.19"	"872.77"	"9.27"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton"	"cytoskeletal activity"	"Pf03250"	"29766"	"ENSG00000138594"	"TMOD3"	"B2R6G7; hsa:29766; Q9NT43; Q9NYL9; Q9NZR0"	"VEGFA-VEGFR2 signaling"	"RND3 GTPase cycle; Striated Muscle Contraction; RHOBTB2 GTPase cycle"	"4"	"0"	"154.7"	"273.5"	"256.5"	"132.9"	"272.3"	"156.3"	"211.7"	"176.1"	"258.9"	"262.3"	"386.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15120"	"[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial OS=Homo sapiens OX=9606 GN=PDK3 PE=1 SV=1"	"8"	"3"	"6"	"3"	"406"	"46.9"	"8.37"	"1051.95"	"9.27"	"3"	"3"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"mitochondrion;nucleus"	"kinase activity;other molecular function"	"Pf02518, Pf10436"	"5165"	"ENSG00000067992"	"PDK3"	"B4DXG6; hsa:5165; Q15120"	""	"Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid"	"2"	"0"	"149.5"	"256.3"	"288.7"	"158.6"	"305.2"	"186.3"	"477.2"	"400.5"	"647.9"	"956.6"	"1524.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55769"	"NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3"	"22"	"2"	"3"	"2"	"128"	"14.2"	"8.46"	"273.83"	"9.25"	"1"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01248"	"4809"	"ENSG00000100138"	"SNU13"	"hsa:4809; P55769"	"mRNA processing"	"mRNA Splicing - Major Pathway; Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"4"	"0"	"85.7"	"168.4"	"164.9"	"75.3"	"148.7"	"102.3"	"150.7"	"150.4"	"248.0"	"517.2"	"1038.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61964"	"WD repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=WDR5 PE=1 SV=1"	"11"	"3"	"6"	"3"	"334"	"36.6"	"8.27"	"849.42"	"9.24"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00400"	"11091"	"ENSG00000196363"	"WDR5"	"hsa:11091; P61964; Q91VA5; Q9NWX7; Q9UGP9"	"Pleural mesothelioma; Kleefstra syndrome"	"Neddylation; Formation of WDR5-containing histone-modifying complexes; Activation of anterior HOX genes in hindbrain development during early embryogenesis; RMTs methylate histone arginines; PKMTs methylate histone lysines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; HATs acetylate histones; Cardiogenesis"	"10"	"0"	"38.3"	"69.7"	"90.0"	"41.0"	"92.1"	"57.5"	"125.3"	"98.1"	"128.4"	"158.3"	"222.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q06787"	"Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1"	"5"	"3"	"5"	"3"	"632"	"71.1"	"7.42"	"647.15"	"9.24"	"2"	"3"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"cytoskeletal activity;translation activity;nucleic acid binding activity;other molecular function"	"Pf00013, Pf05641, Pf12235, Pf16098, Pf17904, Pf18336"	"2332"	"ENSG00000102081"	"FMR1"	"A6NNH4; D3DWT0; D3DWT1; D3DWT2; G8JL90; hsa:2332; Q06787; Q16578; Q5PQZ6; Q99054"	"Ovarian infertility; Serotonin and anxiety; Fragile X syndrome; Disruption of postsynaptic signaling by CNV; 15q11.2 copy number variation syndrome; Primary ovarian insufficiency"	""	"6"	"0"	"172.8"	"393.6"	"372.1"	"141.0"	"361.8"	"164.9"	"398.5"	"301.6"	"418.2"	"495.9"	"749.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q00535"	"Cyclin-dependent-like kinase 5 OS=Homo sapiens OX=9606 GN=CDK5 PE=1 SV=3"	"12"	"3"	"5"	"2"	"292"	"33.3"	"7.66"	"551.08"	"9.23"	"2"	"3"	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;kinase activity;other molecular function"	"Pf00069"	"1020"	"ENSG00000164885"	"CDK5"	"A1XKG3; hsa:1020; Q00535"	"miRNA regulation of DNA damage response; Nicotine effect on dopaminergic neurons; Alzheimer's disease and miRNA effects; Brain-derived neurotrophic factor (BDNF) signaling pathway; ATM signaling in development and disease ; Alzheimer's disease; Neurogenesis regulation in the olfactory epithelium; DNA damage response"	"DARPP-32 events; NPAS4 regulates expression of target genes; NGF-stimulated transcription; Regulation of TP53 Activity through Phosphorylation; Factors involved in megakaryocyte development and platelet production; CRMPs in Sema3A signaling; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models; Activated NTRK2 signals through CDK5"	"16"	"0"	"26.6"	"76.9"	"75.5"	"32.3"	"75.6"	"34.3"	"105.6"	"124.9"	"227.5"	"305.4"	"422.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14257"	"Reticulocalbin-2 OS=Homo sapiens OX=9606 GN=RCN2 PE=1 SV=1"	"9"	"2"	"4"	"2"	"317"	"36.9"	"4.40"	"1136.23"	"9.23"	"2"	"2"	""	"ER/Golgi;nucleus"	"other molecular function"	"Pf13202"	"5955"	"ENSG00000117906"	"RCN2"	"A8MTG6; F8WCY5; hsa:5955; Q14257; Q53XN8"	""	""	"0"	"0"	"51.3"	"129.2"	"132.3"	"40.1"	"106.2"	"62.7"	"192.9"	"148.6"	"225.2"	"251.3"	"425.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15843"	"NEDD8 OS=Homo sapiens OX=9606 GN=NEDD8 PE=1 SV=1"	"25"	"3"	"4"	"3"	"81"	"9.1"	"8.43"	"598.73"	"9.23"	"1"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00240"	"4738"	"ENSG00000129559; ENSG00000285246"	"NEDD8"	"hsa:4738; Q15843; Q3SXN8; Q6LES6"	"EGF/EGFR signaling pathway; 2q37 copy number variation syndrome"	"UCH proteinases; Neddylation; Cargo recognition for clathrin-mediated endocytosis; Iron uptake and transport; TGF-beta receptor signaling activates SMADs"	"7"	"0"	"174.0"	"955.9"	"929.4"	"110.8"	"785.2"	"234.5"	"327.2"	"222.8"	"337.4"	"368.4"	"798.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13643"	"Four and a half LIM domains protein 3 OS=Homo sapiens OX=9606 GN=FHL3 PE=1 SV=4"	"10"	"3"	"6"	"3"	"280"	"31.2"	"6.20"	"1027.07"	"9.23"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other biological processes"	"cytoskeleton;nucleus"	"cytoskeletal activity;other molecular function"	"Pf00412"	"2275"	"ENSG00000183386"	"FHL3"	"D3DPT6; hsa:2275; Q13643; Q6I9T0; Q9BVA2"	""	""	"0"	"0"	"214.5"	"348.3"	"364.1"	"165.4"	"334.8"	"227.0"	"290.0"	"231.8"	"306.7"	"467.9"	"643.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60547"	"GDP-mannose 4,6 dehydratase OS=Homo sapiens OX=9606 GN=GMDS PE=1 SV=1"	"16"	"4"	"6"	"4"	"372"	"41.9"	"7.31"	"878.85"	"9.21"	"3"	"3"	"other metabolic processes;signal transduction"	"cytosol;other cell component"	"other molecular function"	"Pf16363"	"2762"	"ENSG00000112699"	"GMDS"	"E9PI88; hsa:2762; O60547; O75357; Q5T954; Q6FH09; Q9UGZ3; Q9UJK9"	""	"GDP-fucose biosynthesis"	"1"	"0"	"164.7"	"307.0"	"281.2"	"132.0"	"268.4"	"142.9"	"237.8"	"190.1"	"238.8"	"329.0"	"489.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H0C8"	"Integrin-linked kinase-associated serine/threonine phosphatase 2C OS=Homo sapiens OX=9606 GN=ILKAP PE=1 SV=1"	"5"	"2"	"5"	"2"	"392"	"42.9"	"7.09"	"722.48"	"9.20"	"2"	"2"	"protein metabolism;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf00481"	"80895"	"ENSG00000132323"	"ILKAP"	"B3KM39; hsa:80895; Q9H0C8"	"2q37 copy number variation syndrome"	""	"1"	"0"	"56.4"	"211.8"	"193.5"	"50.7"	"157.1"	"66.8"	"228.5"	"177.6"	"252.3"	"446.5"	"788.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13200"	"26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3"	"3"	"2"	"5"	"2"	"908"	"100.1"	"5.20"	"758.11"	"9.19"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf01851, Pf17781, Pf18051"	"5708"	"ENSG00000175166"	"PSMD2"	"B4DX07; B4DXY1; E7EW34; E9PCS3; hsa:5708; Q12932; Q13200; Q15321; Q53XQ4; Q96I12"	"Proteasome degradation; Alzheimer's disease and miRNA effects; TNF-alpha signaling pathway; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"Antigen processing: Ubiquitination & Proteasome degradation; AUF1 (hnRNP D0) binds and destabilizes mRNA; MAPK6/MAPK4 signaling; Downstream TCR signaling; FCERI mediated NF-kB activation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"65"	"0"	"102.8"	"258.0"	"268.2"	"108.0"	"230.0"	"116.1"	"147.3"	"133.1"	"249.1"	"321.2"	"518.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q53GS9"	"U4/U6.U5 tri-snRNP-associated protein 2 OS=Homo sapiens OX=9606 GN=USP39 PE=1 SV=2"	"7"	"3"	"5"	"3"	"565"	"65.3"	"8.91"	"756.46"	"9.19"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00443, Pf02148"	"10713"	"ENSG00000168883"	"USP39"	"A8K086; B3KM40; B4DHT4; D6W5L4; G5E9H0; hsa:10713; Q53GS9; Q6NX47; Q96RK9; Q9BV89; Q9H381; Q9P050; Q9Y310"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"54.4"	"114.3"	"130.3"	"47.7"	"116.0"	"66.2"	"188.5"	"141.6"	"209.8"	"263.4"	"389.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15173"	"Membrane-associated progesterone receptor component 2 OS=Homo sapiens OX=9606 GN=PGRMC2 PE=1 SV=1"	"8"	"2"	"6"	"1"	"223"	"23.8"	"4.88"	"972.45"	"9.18"	"2"	"2"	"transport;signal transduction;other biological processes"	"ER/Golgi;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf00173"	"10424"	"ENSG00000164040"	"PGRMC2"	"hsa:10424; O15173; Q569H1"	"Ciliary landscape"	"RHOA GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOD GTPase cycle"	"6"	"0"	"38.3"	"152.6"	"132.7"	"26.8"	"116.2"	"47.2"	"71.9"	"67.4"	"85.0"	"145.4"	"235.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05198"	"Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3"	"12"	"3"	"5"	"3"	"315"	"36.1"	"5.08"	"699.49"	"9.17"	"2"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf00575, Pf07541"	"1965"	"ENSG00000134001"	"EIF2S1"	"hsa:1965; P05198"	"Translation factors; Alzheimer's disease and miRNA effects; Brain-derived neurotrophic factor (BDNF) signaling pathway; Ebola virus infection in host; Nonalcoholic fatty liver disease; Measles virus infection; Unfolded protein response; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell; Alzheimer's disease"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; ABC-family proteins mediated transport; Response of EIF2AK1 (HRI) to heme deficiency; PERK regulates gene expression; Recycling of eIF2:GDP; Response of EIF2AK4 (GCN2) to amino acid deficiency"	"19"	"0"	"40.7"	"70.6"	"76.4"	"39.1"	"80.5"	"51.9"	"104.8"	"80.5"	"124.6"	"226.2"	"369.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95218"	"Zinc finger Ran-binding domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ZRANB2 PE=1 SV=2"	"9"	"3"	"6"	"3"	"330"	"37.4"	"10.01"	"1126.26"	"9.17"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00641"	"9406"	"ENSG00000132485"	"ZRANB2"	"D3DQ75; hsa:9406; O95218; Q53GS3; Q59F92; Q5VV33; Q5VV34; Q8IXN6; Q9UP63"	""	""	"0"	"0"	"237.7"	"579.9"	"581.3"	"178.1"	"532.3"	"270.4"	"909.3"	"545.5"	"676.5"	"780.0"	"1210.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BSJ8"	"Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1"	"3"	"2"	"4"	"2"	"1104"	"122.8"	"5.83"	"904.48"	"9.14"	"2"	"2"	"cell organization and biogenesis;transport"	"plasma membrane;other membranes;ER/Golgi"	"transporter activity;other molecular function"	"Pf00168, Pf17047"	"23344"	"ENSG00000139641"	"ESYT1"	"A0FGR7; A8K2S2; hsa:23344; O94848; Q6PJN4; Q9BSJ8; Q9H6J1; Q9H6W2; Q9Y416"	""	"RAC1 GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOD GTPase cycle; Glycosphingolipid metabolism; RHOF GTPase cycle"	"7"	"0"	"29.3"	"46.3"	"53.5"	"29.8"	"60.0"	"34.0"	"55.9"	"48.7"	"69.2"	"98.5"	"110.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P20962"	"Parathymosin OS=Homo sapiens OX=9606 GN=PTMS PE=1 SV=2"	"23"	"2"	"6"	"2"	"102"	"11.5"	"4.16"	"1224.16"	"9.11"	"2"	"2"	"DNA metabolism;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf03247"	"5763"	"ENSG00000159335"	"PTMS"	"hsa:5763; P20962"	"IL-18 signaling pathway"	""	"1"	"0"	"92.5"	"551.1"	"527.5"	"38.0"	"424.5"	"128.3"	"205.3"	"121.0"	"163.2"	"178.9"	"447.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62633"	"Cellular nucleic acid-binding protein OS=Homo sapiens OX=9606 GN=CNBP PE=1 SV=1"	"16"	"2"	"2"	"2"	"177"	"19.5"	"7.71"	""	"9.10"	""	"2"	"DNA metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00098"	"7555"	"ENSG00000169714"	"CNBP"	"A8K7V4; B2RAV9; B4DP17; D3DNB9; D3DNC0; D3DNC1; E9PDR7; hsa:7555; P20694; P62633; Q4JGY0; Q4JGY1; Q5QJR0; Q5U0E9; Q6PJI7; Q96NV3"	""	"SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"1"	"0"	"98.2"	"304.2"	"228.7"	"63.7"	"245.2"	"95.5"	"149.8"	"124.7"	"169.4"	"178.9"	"324.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P015"	"39S ribosomal protein L15, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL15 PE=1 SV=1"	"13"	"3"	"6"	"3"	"296"	"33.4"	"10.01"	"1002.03"	"9.10"	"3"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00828"	"29088"	"ENSG00000137547"	"MRPL15"	"hsa:29088; Q96Q54; Q9H0Y1; Q9P015"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"118.0"	"242.8"	"257.4"	"105.4"	"230.9"	"147.9"	"162.4"	"128.0"	"173.3"	"214.0"	"374.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75962"	"Triple functional domain protein OS=Homo sapiens OX=9606 GN=TRIO PE=1 SV=2"	"1"	"2"	"4"	"2"	"3097"	"346.7"	"6.37"	"800.31"	"9.09"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00018, Pf00069, Pf00169, Pf00435, Pf00621, Pf00650, Pf07679, Pf16609"	"7204"	"ENSG00000038382"	"TRIO"	"D3DTD1; hsa:7204; O75962; Q13458; Q59EQ7; Q6PJC9; Q6ZN05; Q8IWK8"	"Microtubule cytoskeleton regulation; Neural crest cell migration during development; Neural crest cell migration in cancer"	"RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; NRAGE signals death through JNK; G alpha (12/13) signalling events; RHOG GTPase cycle; G alpha (q) signalling events; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOJ GTPase cycle; DCC mediated attractive signaling"	"14"	"0"	"22.6"	"56.8"	"51.9"	"28.2"	"58.3"	"26.7"	"94.5"	"137.4"	"280.4"	"344.5"	"389.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NYB9"	"Abl interactor 2 OS=Homo sapiens OX=9606 GN=ABI2 PE=1 SV=1"	"6"	"3"	"5"	"1"	"513"	"55.6"	"6.16"	"683.38"	"9.08"	"2"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf07815, Pf14604"	"10152"	"ENSG00000138443"	"ABI2"	"B4DSN1; hsa:10152; Q13147; Q13249; Q13801; Q9BV70; Q9NYB9"	"Regulation of actin cytoskeleton"	"RAC1 GTPase cycle; RAC3 GTPase cycle; RAC2 GTPase cycle; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; VEGFA-VEGFR2 Pathway"	"8"	"0"	"25.6"	"56.9"	"47.5"	"22.1"	"50.3"	"28.4"	"80.0"	"61.3"	"102.9"	"164.7"	"223.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35249"	"Replication factor C subunit 4 OS=Homo sapiens OX=9606 GN=RFC4 PE=1 SV=2"	"12"	"3"	"5"	"3"	"363"	"39.7"	"8.02"	"739.91"	"9.08"	"2"	"3"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00004, Pf08542"	"5984"	"ENSG00000163918"	"RFC4"	"B4DM41; D3DNV2; hsa:5984; P35249; Q6FHX7"	"Gastric cancer network 2; Retinoblastoma gene in cancer; DNA replication; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"Activation of ATR in response to replication stress; Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Polymerase switching on the C-strand of the telomere; Polymerase switching; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER"	"28"	"0"	"132.6"	"253.3"	"265.1"	"95.7"	"251.4"	"145.6"	"297.2"	"252.8"	"406.8"	"567.7"	"840.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52292"	"Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1"	"8"	"3"	"6"	"3"	"529"	"57.8"	"5.40"	"923.84"	"9.07"	"3"	"3"	"DNA metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00514, Pf01749, Pf16186"	"3838"	"ENSG00000182481"	"KPNA2"	"B9EJD6; hsa:3838; P52292; Q53YE3; Q6NVW7; Q9BRU5"	""	"ISG15 antiviral mechanism; NS1 Mediated Effects on Host Pathways; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Estrogen-dependent gene expression; SARS-CoV-1 activates/modulates innate immune responses; Sensing of DNA Double Strand Breaks; CaMK IV-mediated phosphorylation of CREB; CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde"	"8"	"0"	"72.1"	"225.5"	"217.6"	"58.6"	"158.6"	"78.3"	"159.5"	"123.3"	"189.8"	"251.8"	"318.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15020"	"Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1"	"5"	"5"	"8"	"5"	"963"	"109.9"	"5.57"	"1497.00"	"9.07"	"5"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00076, Pf05391, Pf16605"	"9733"	"ENSG00000075856"	"SART3"	"A8K2E4; B7ZKM0; hsa:9733; Q15020; Q2M2H0; Q58F06; Q8IUS1; Q96J95"	""	""	"0"	"0"	"355.1"	"686.2"	"827.7"	"310.4"	"646.9"	"404.7"	"779.8"	"652.2"	"915.3"	"1002.4"	"1375.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BVP2"	"Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2"	"11"	"4"	"6"	"4"	"549"	"62.0"	"9.16"	"827.36"	"9.06"	"3"	"3"	"cell cycle OR cell proliferation;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01926, Pf08701"	"26354"	"ENSG00000163938"	"GNL3"	"B2RDC1; hsa:26354; Q5PU80; Q96SV6; Q96SV7; Q9BVP2; Q9UJY0"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"26.5"	"67.9"	"68.5"	"23.9"	"60.3"	"31.1"	"55.3"	"37.9"	"45.5"	"68.1"	"101.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35659"	"Protein DEK OS=Homo sapiens OX=9606 GN=DEK PE=1 SV=1"	"8"	"3"	"6"	"3"	"375"	"42.6"	"8.56"	"1011.79"	"9.03"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytoskeleton;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf08766"	"7913"	"ENSG00000124795"	"DEK"	"B2R6K6; B4DN37; hsa:7913; P35659; Q5TGV4; Q5TGV5"	"IL-18 signaling pathway"	"B-WICH complex positively regulates rRNA expression; Transcriptional regulation of granulopoiesis; Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors"	"4"	"0"	"133.5"	"329.9"	"320.9"	"109.1"	"301.9"	"150.0"	"376.0"	"277.9"	"428.8"	"547.3"	"918.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y266"	"Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1"	"12"	"4"	"7"	"4"	"331"	"38.2"	"5.38"	"1465.72"	"9.01"	"4"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf04969, Pf14050, Pf16273"	"10726"	"ENSG00000090273"	"NUDC"	"hsa:10726; Q5QP31; Q5QP35; Q9H0N2; Q9Y266; Q9Y2B6"	"Ciliary landscape"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; RND2 GTPase cycle; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"8"	"0"	"269.4"	"1098.2"	"951.7"	"212.8"	"822.4"	"332.0"	"483.1"	"343.8"	"468.8"	"574.9"	"999.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P48047"	"ATP synthase subunit O, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PO PE=1 SV=1"	"13"	"3"	"6"	"3"	"213"	"23.3"	"9.96"	"1040.30"	"9.01"	"3"	"3"	"other metabolic processes;transport"	"plasma membrane;other membranes;mitochondrion"	"transporter activity"	"Pf00213"	"539"	"ENSG00000241837"	"ATP5PO"	"B2R4E2; hsa:539; P48047; Q5U042; Q6IBI2"	"Electron transport chain: OXPHOS system in mitochondria; 7q11.23 copy number variation syndrome; Oxidative phosphorylation"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"5"	"0"	"263.7"	"702.5"	"707.9"	"241.4"	"619.9"	"301.5"	"442.6"	"374.8"	"615.3"	"728.3"	"1287.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NYR9"	"NF-kappa-B inhibitor-interacting Ras-like protein 2 OS=Homo sapiens OX=9606 GN=NKIRAS2 PE=1 SV=1"	"15"	"3"	"4"	"3"	"191"	"21.5"	"8.05"	"339.61"	"9.00"	"1"	"3"	"stress response;developmental processes;signal transduction;other biological processes"	"other cell component"	"other molecular function"	"Pf00071"	"28511"	"ENSG00000168256"	"NKIRAS2"	"A6NCZ5; B3KNN0; B4DNM3; hsa:28511; Q6PK52; Q96KC7; Q9NSX1; Q9NYR9"	""	"RIP-mediated NFkB activation via ZBP1; TAK1-dependent IKK and NF-kappa-B activation  ; TRAF6 mediated NF-kB activation"	"3"	"0"	"58.8"	"147.3"	"141.0"	"67.7"	"130.8"	"57.2"	"143.6"	"148.1"	"414.7"	"671.4"	"777.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P84101"	"Small EDRK-rich factor 2 OS=Homo sapiens OX=9606 GN=SERF2 PE=1 SV=1"	"17"	"2"	"6"	"2"	"59"	"6.9"	"10.45"	"1150.52"	"8.98"	"2"	"2"	"other biological processes"	"cytosol;nucleus"	""	"Pf04419"	"10169"	"ENSG00000140264"	"SERF2"	"A6NL45; B5MCG1; B9A026; hsa:10169; O75918; O88891; P84101; Q9BZH7"	""	""	"0"	"0"	"413.8"	"321.5"	"328.1"	"318.8"	"473.8"	"348.9"	"905.2"	"619.3"	"851.2"	"1028.2"	"1395.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61513"	"60S ribosomal protein L37a OS=Homo sapiens OX=9606 GN=RPL37A PE=1 SV=2"	"42"	"3"	"5"	"3"	"92"	"10.3"	"10.43"	"685.92"	"8.98"	"2"	"2"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01780"	"6168"	"ENSG00000197756"	"RPL37A"	"hsa:6168; P12751; P61513; Q6FGF5"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; SRP-dependent cotranslational protein targeting to membrane; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"85.2"	"249.3"	"165.2"	"96.2"	"172.5"	"101.1"	"249.9"	"242.2"	"268.6"	"344.3"	"473.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19525"	"Interferon-induced, double-stranded RNA-activated protein kinase OS=Homo sapiens OX=9606 GN=EIF2AK2 PE=1 SV=2"	"4"	"2"	"6"	"2"	"551"	"62.1"	"8.40"	"1023.10"	"8.96"	"2"	"2"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;kinase activity;other molecular function"	"Pf00035, Pf00069"	"5610"	"ENSG00000055332"	"EIF2AK2"	"A8K3P0; D6W584; E9PC80; hsa:5610; P19525; Q52M43; Q7Z6F6; Q9UIR4"	"Translation factors; Alzheimer's disease and miRNA effects; Ebola virus infection in host; Measles virus infection; Type I interferon induction and signaling during SARS-CoV-2 infection; Host-pathogen interaction of human coronaviruses - interferon induction; Alzheimer's disease; Roles of ceramides in development of insulin resistance; Type II interferon signaling"	"ISG15 antiviral mechanism; Interferon alpha/beta signaling; Inhibition of PKR"	"12"	"0"	"68.8"	"191.6"	"190.3"	"76.1"	"141.4"	"81.1"	"215.0"	"157.0"	"375.6"	"540.7"	"757.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08133"	"Annexin A6 OS=Homo sapiens OX=9606 GN=ANXA6 PE=1 SV=3"	"5"	"3"	"6"	"3"	"673"	"75.8"	"5.60"	"1000.43"	"8.95"	"3"	"3"	"cell organization and biogenesis;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;mitochondrion;other cytoplasmic organelle;other cell component"	"transporter activity;cytoskeletal activity;other molecular function"	"Pf00191"	"309"	"ENSG00000197043"	"ANXA6"	"B7Z8A7; D3DQH4; E9PGK1; hsa:309; P08133; Q6ZT79"	"Calcium regulation in cardiac cells; Prostaglandin synthesis and regulation"	"Smooth Muscle Contraction"	"3"	"0"	"25.2"	"85.2"	"106.1"	"26.9"	"69.3"	"43.2"	"68.0"	"57.2"	"88.7"	"137.4"	"341.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01968"	"Inositol polyphosphate 5-phosphatase OCRL OS=Homo sapiens OX=9606 GN=OCRL PE=1 SV=3"	"4"	"3"	"6"	"3"	"901"	"104.1"	"6.55"	"1000.67"	"8.90"	"3"	"3"	"cell organization and biogenesis;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00620, Pf03372, Pf16726"	"4952"	"ENSG00000122126"	"OCRL"	"A6NKI1; A8KAP2; B7ZLX2; hsa:4952; O60800; Q01968; Q15684; Q15774; Q4VY09; Q4VY10; Q5JQF1; Q5JQF2; Q9UJG5; Q9UMA5"	"VEGFA-VEGFR2 signaling; Ciliopathies; Bardet-Biedl syndrome"	"Clathrin-mediated endocytosis; RAC3 GTPase cycle; RHOJ GTPase cycle; Golgi Associated Vesicle Biogenesis; Synthesis of PIPs at the plasma membrane; Synthesis of PIPs at the Golgi membrane; Synthesis of IP2, IP, and Ins in the cytosol; Synthesis of IP3 and IP4 in the cytosol"	"11"	"0"	"85.5"	"164.2"	"186.0"	"80.7"	"186.2"	"98.0"	"254.7"	"267.8"	"475.7"	"881.8"	"1581.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BUQ8"	"Probable ATP-dependent RNA helicase DDX23 OS=Homo sapiens OX=9606 GN=DDX23 PE=1 SV=3"	"5"	"4"	"6"	"4"	"820"	"95.5"	"9.55"	"574.77"	"8.90"	"2"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271"	"9416"	"ENSG00000174243"	"DDX23"	"B2R600; B4DH15; hsa:9416; O43188; Q9BUQ8"	""	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"2"	"0"	"81.5"	"304.1"	"286.1"	"74.4"	"267.2"	"103.7"	"233.1"	"192.7"	"257.5"	"393.6"	"610.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P84243"	"Histone H3.3 OS=Homo sapiens OX=9606 GN=H3-3A PE=1 SV=2"	"18"	"3"	"5"	"3"	"136"	"15.3"	"11.27"	"543.23"	"8.87"	"2"	"3"	"cell organization and biogenesis;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125"	"3020; 3021"	"ENSG00000132475; ENSG00000163041"	"H3-3A; H3-3B"	"hsa:3020; hsa:3021; P06351; P33155; P84243; Q5VV55; Q5VV56; Q66I33; Q9V3W4"	"Gastric cancer network 1; Histone modifications; Tumor suppressor activity of SMARCB1; Ciliary landscape; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; DYRK1A involvement regarding cell proliferation in brain development"	"Factors involved in megakaryocyte development and platelet production; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Formation of the beta-catenin:TCF transactivating complex; Transcriptional regulation by small RNAs; B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; RNA Polymerase I Promoter Escape; Inhibition of DNA recombination at telomere; Amyloid fiber formation; Oxidative Stress Induced Senescence; Pre-NOTCH Transcription and Translation; Senescence-Associated Secretory Phenotype (SASP); RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Meiotic recombination; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Condensation of Prophase Chromosomes; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis"	"32"	"0"	"115.7"	"334.9"	"371.5"	"86.5"	"228.1"	"105.6"	"139.1"	"130.9"	"165.4"	"233.0"	"316.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"E9PAV3"	"Nascent polypeptide-associated complex subunit alpha, muscle-specific form OS=Homo sapiens OX=9606 GN=NACA PE=1 SV=1"	"1"	"3"	"7"	"3"	"2078"	"205.3"	"9.58"	"1281.08"	"8.85"	"3"	"2"	"transport"	"translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01849, Pf19026"	""	"ENSG00000196531"	"NACA"	"E9PAV3"	""	""	"0"	"0"	"20.2"	"53.8"	"61.4"	"20.2"	"61.5"	"31.0"	"40.6"	"32.3"	"43.8"	"79.4"	"76.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12904"	"Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 OS=Homo sapiens OX=9606 GN=AIMP1 PE=1 SV=2"	"11"	"3"	"6"	"3"	"312"	"34.3"	"8.43"	"858.85"	"8.84"	"3"	"3"	"cell-cell signaling;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf01588"	"9255"	"ENSG00000164022"	"AIMP1"	"B3KTR2; B4E1S7; hsa:9255; Q12904; Q6FG28; Q96CQ9"	"Ciliary landscape"	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"3"	"0"	"132.1"	"356.3"	"352.7"	"108.0"	"318.9"	"152.9"	"291.3"	"243.3"	"367.7"	"556.2"	"1135.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P00390"	"Glutathione reductase, mitochondrial OS=Homo sapiens OX=9606 GN=GSR PE=1 SV=2"	"7"	"3"	"6"	"3"	"522"	"56.2"	"8.50"	"887.40"	"8.82"	"3"	"3"	"other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion"	"other molecular function"	"Pf00070, Pf02852"	"2936"	"ENSG00000104687"	"GSR"	"C8KIL8; C8KIL9; C8KIM0; D3DSV3; hsa:2936; P00390; Q7Z5C9; Q9NP63"	"Glutathione metabolism; Selenium micronutrient network; Trans-sulfuration, one-carbon metabolism and related pathways; Nuclear receptors meta-pathway; NRF2 pathway; Amino acid metabolism; Oxidative stress response; Vitamin D-sensitive calcium signaling in depression; Sulfation biotransformation reaction; Metapathway biotransformation Phase I and II"	""	"10"	"0"	"22.8"	"106.4"	"92.9"	"26.5"	"89.0"	"25.9"	"44.4"	"48.5"	"86.8"	"123.0"	"200.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95168"	"NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 OS=Homo sapiens OX=9606 GN=NDUFB4 PE=1 SV=3"	"32"	"3"	"6"	"3"	"129"	"15.2"	"9.85"	"963.75"	"8.81"	"3"	"3"	"cell organization and biogenesis;other metabolic processes;stress response;transport"	"other membranes;mitochondrion;nucleus"	"transporter activity"	"Pf07225"	"4710"	"ENSG00000065518"	"NDUFB4"	"B2RUY3; B9EJC7; hsa:4710; O95168"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"120.8"	"331.2"	"300.1"	"101.7"	"282.8"	"128.7"	"207.4"	"174.8"	"307.6"	"464.4"	"806.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43813"	"Glutathione S-transferase LANCL1 OS=Homo sapiens OX=9606 GN=LANCL1 PE=1 SV=1"	"9"	"3"	"6"	"3"	"399"	"45.3"	"7.75"	"1045.92"	"8.80"	"3"	"3"	"other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf05147"	"10314"	"ENSG00000115365"	"LANCL1"	"hsa:10314; O43813"	""	""	"0"	"0"	"88.6"	"136.9"	"157.3"	"87.0"	"129.0"	"87.2"	"243.5"	"207.6"	"244.2"	"294.8"	"396.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08579"	"U2 small nuclear ribonucleoprotein B'' OS=Homo sapiens OX=9606 GN=SNRPB2 PE=1 SV=1"	"12"	"3"	"6"	"2"	"225"	"25.5"	"9.72"	"969.78"	"8.79"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6629"	"ENSG00000125870"	"SNRPB2"	"B2R7J3; D3DW21; hsa:6629; P08579; Q9UJD4"	"mRNA processing; Ciliary landscape"	"mRNA Splicing - Major Pathway"	"3"	"0"	"182.8"	"245.6"	"294.4"	"144.7"	"304.2"	"186.5"	"306.2"	"189.1"	"318.2"	"355.9"	"484.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05114"	"Non-histone chromosomal protein HMG-14 OS=Homo sapiens OX=9606 GN=HMGN1 PE=1 SV=3"	"31"	"3"	"6"	"3"	"100"	"10.7"	"9.60"	"804.29"	"8.78"	"3"	"3"	"cell organization and biogenesis;DNA metabolism;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01101"	"3150"	"ENSG00000205581"	"HMGN1"	"hsa:3150; P05114; Q3KQR8"	"ATM signaling in development and disease ; p38 MAPK signaling pathway; Pleural mesothelioma; Nucleotide excision repair in xeroderma pigmentosum"	"Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	"8"	"0"	"170.3"	"310.2"	"298.7"	"118.6"	"269.7"	"164.6"	"411.7"	"276.4"	"426.4"	"484.1"	"751.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99615"	"DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2"	"6"	"3"	"6"	"3"	"494"	"56.4"	"6.96"	"957.24"	"8.78"	"3"	"3"	"other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00226, Pf13181, Pf13414, Pf13432"	"7266"	"ENSG00000168259"	"DNAJC7"	"hsa:7266; Q7Z784; Q99615"	"Constitutive androstane receptor pathway; Pregnane X receptor pathway; Nuclear receptors meta-pathway"	"Regulation of HSF1-mediated heat shock response"	"4"	"0"	"99.5"	"210.5"	"365.5"	"165.1"	"331.0"	"235.6"	"445.0"	"350.2"	"388.8"	"576.8"	"808.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04908"	"Histone H2A type 1-B/E OS=Homo sapiens OX=9606 GN=H2AC4 PE=1 SV=2"	"22"	"2"	"6"	"2"	"130"	"14.1"	"11.05"	"927.47"	"8.77"	"2"	"2"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125, Pf16211"	"3012; 8335"	"ENSG00000277075; ENSG00000278463"	"H2AC4; H2AC8"	"hsa:3012; hsa:8335; P04908; P28001; Q76P63"	"Proteasome degradation"	"Deposition of new CENPA-containing nucleosomes at the centromere; B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; Amyloid fiber formation; Meiotic synapsis; HCMV Late Events; UCH proteinases; Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; HCMV Early Events; Transcriptional regulation by small RNAs; Formation of the beta-catenin:TCF transactivating complex; Oxidative Stress Induced Senescence; HDACs deacetylate histones; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Metalloprotease DUBs; Pre-NOTCH Transcription and Translation; Senescence-Associated Secretory Phenotype (SASP); RMTs methylate histone arginines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; HATs acetylate histones; RNA Polymerase I Promoter Escape; Meiotic recombination; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Packaging Of Telomere Ends; Condensation of Prophase Chromosomes; DNA Damage/Telomere Stress Induced Senescence; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis"	"42"	"0"	"126.0"	"383.7"	"453.1"	"95.9"	"278.6"	"137.6"	"287.2"	"233.5"	"409.8"	"481.5"	"746.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6UX04"	"Spliceosome-associated protein CWC27 homolog OS=Homo sapiens OX=9606 GN=CWC27 PE=1 SV=1"	"6"	"3"	"6"	"3"	"472"	"53.8"	"5.80"	"1035.87"	"8.77"	"3"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	"Pf00160"	"10283"	"ENSG00000153015"	"CWC27"	"hsa:10283; O60529; O60530; Q6UX04; Q96EM3"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"107.7"	"133.8"	"141.5"	"75.5"	"178.6"	"111.3"	"183.7"	"113.8"	"184.5"	"205.9"	"245.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13523"	"Serine/threonine-protein kinase PRP4 homolog OS=Homo sapiens OX=9606 GN=PRPF4B PE=1 SV=3"	"2"	"2"	"6"	"2"	"1007"	"116.9"	"10.26"	"995.13"	"8.73"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"8899"	"ENSG00000112739"	"PRPF4B"	"A8K5C9; hsa:8899; Q13523; Q5D0F6; Q5TAY8; Q8IVC3; Q8TDP2; Q96QT7; Q9UEE6"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"4.1"	"32.0"	"39.6"	"10.7"	"24.6"	"13.9"	"29.0"	"23.6"	"47.5"	"76.0"	"94.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P42766"	"60S ribosomal protein L35 OS=Homo sapiens OX=9606 GN=RPL35 PE=1 SV=2"	"32"	"4"	"6"	"3"	"123"	"14.5"	"11.05"	"978.91"	"8.73"	"3"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00831"	"11224"	"ENSG00000136942"	"RPL35"	"A8K4V7; hsa:11224; P42766; Q4VBY5; Q5JTN5; Q6IBC7; Q96QJ7; Q9BYF4"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"117.6"	"296.0"	"278.4"	"106.4"	"272.6"	"131.1"	"342.8"	"306.9"	"332.0"	"434.8"	"586.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15436"	"Protein transport protein Sec23A OS=Homo sapiens OX=9606 GN=SEC23A PE=1 SV=2"	"5"	"3"	"7"	"2"	"765"	"86.1"	"7.08"	"1469.48"	"8.69"	"3"	"3"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00626, Pf04810, Pf04811, Pf04815, Pf08033"	"10484"	"ENSG00000100934"	"SEC23A"	"B2R5P4; B3KXI2; hsa:10484; Q15436; Q8NE16"	"Sterol regulatory element-binding proteins (SREBP) signaling"	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC; MHC class II antigen presentation; SARS-CoV-2 activates/modulates innate and adaptive immune responses; COPII-mediated vesicle transport; Cargo concentration in the ER; Regulation of cholesterol biosynthesis by SREBP (SREBF)"	"7"	"1"	"31.5"	"69.0"	"76.7"	"22.3"	"74.3"	"33.1"	"156.0"	"125.7"	"157.9"	"214.3"	"284.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92769"	"Histone deacetylase 2 OS=Homo sapiens OX=9606 GN=HDAC2 PE=1 SV=2"	"7"	"3"	"7"	"1"	"488"	"55.3"	"5.91"	"1157.65"	"8.66"	"2"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00850"	"3066"	"ENSG00000196591"	"HDAC2"	"B3KRS5; B4DL58; E1P561; hsa:3066; Q5SRI8; Q5SZ86; Q8NEH4; Q92769"	"Cell cycle; Neural crest differentiation; Notch signaling; Initiation of transcription and translation elongation at the HIV-1 LTR; Ethanol effects on histone modifications; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; Ciliary landscape; 7q11.23 copy number variation syndrome; SARS-CoV-2 innate immunity evasion and cell-specific immune response; Notch signaling pathway"	"HDACs deacetylate histones; NoRC negatively regulates rRNA expression; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; SUMOylation of chromatin organization proteins; Factors involved in megakaryocyte development and platelet production; Potential therapeutics for SARS; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes; Regulation of PTEN gene transcription; RNA Polymerase I Transcription Initiation; p75NTR negatively regulates cell cycle via SC1; NOTCH1 Intracellular Domain Regulates Transcription; Notch-HLH transcription pathway; Regulation of MECP2 expression and activity; STAT3 nuclear events downstream of ALK signaling; Regulation of TP53 Activity through Acetylation; EGR2 and SOX10-mediated initiation of Schwann cell myelination; MECP2 regulates neuronal receptors and channels"	"29"	"0"	"53.2"	"92.4"	"108.2"	"58.6"	"123.7"	"80.7"	"157.8"	"65.2"	"130.9"	"139.6"	"145.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30085"	"UMP-CMP kinase OS=Homo sapiens OX=9606 GN=CMPK1 PE=1 SV=3"	"10"	"2"	"5"	"2"	"196"	"22.2"	"5.57"	"712.77"	"8.66"	"1"	"2"	"other metabolic processes"	"cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00406"	"51727"	"ENSG00000162368"	"CMPK1"	"B2R6S5; B4DPU7; E9PGI8; hsa:51727; P30085; Q53GB7; Q5SVZ0; Q96C07; Q9UBQ8; Q9UIA2"	"Pyrimidine metabolism"	"Interconversion of nucleotide di- and triphosphates"	"2"	"0"	"58.3"	"314.3"	"275.6"	"38.4"	"220.6"	"84.3"	"109.2"	"98.6"	"115.7"	"179.3"	"275.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H4G4"	"Golgi-associated plant pathogenesis-related protein 1 OS=Homo sapiens OX=9606 GN=GLIPR2 PE=1 SV=3"	"8"	"1"	"4"	"1"	"154"	"17.2"	"9.41"	"921.00"	"8.66"	"1"	"1"	"other biological processes"	"non-structural extracellular;other membranes;ER/Golgi"	"other molecular function"	"Pf00188"	"152007"	"ENSG00000122694"	"GLIPR2"	"hsa:152007; Q5VZR1; Q8N2S6; Q8WWC9; Q8WX36; Q9H4G4"	""	""	"0"	"0"	"61.2"	"88.5"	"87.4"	"69.4"	"109.5"	"70.0"	"146.9"	"164.6"	"363.7"	"599.8"	"906.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19784"	"Casein kinase II subunit alpha' OS=Homo sapiens OX=9606 GN=CSNK2A2 PE=1 SV=1"	"9"	"3"	"6"	"3"	"350"	"41.2"	"8.56"	"817.50"	"8.65"	"3"	"3"	"cell-cell signaling;cell cycle OR cell proliferation;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"1459"	"ENSG00000070770"	"CSNK2A2"	"hsa:1459; P19784"	"Alzheimer's disease and miRNA effects; Allograft rejection; lncRNA in canonical Wnt signaling and colorectal cancer; Breast cancer pathway; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Measles virus infection; Pleural mesothelioma; Alzheimer's disease"	"Regulation of PTEN stability and activity; KEAP1-NFE2L2 pathway; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Regulation of TP53 Activity through Phosphorylation; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; WNT mediated activation of DVL; Signal transduction by L1; Receptor Mediated Mitophagy; Condensation of Prometaphase Chromosomes; Synthesis of PC"	"19"	"0"	"68.9"	"254.9"	"238.7"	"77.0"	"213.5"	"83.6"	"291.1"	"262.3"	"343.2"	"493.2"	"853.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14654"	"Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1"	"3"	"3"	"5"	"3"	"1257"	"133.7"	"8.44"	"498.47"	"8.64"	"2"	"3"	"signal transduction"	"plasma membrane;other membranes;cytosol"	"signal transduction activity or receptor binding;other molecular function"	"Pf02174"	"8471"	"ENSG00000133124"	"IRS4"	"hsa:8471; O14654"	"Alzheimer's disease and miRNA effects; Adipogenesis; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Leptin-insulin signaling overlap; Insulin signaling; Alzheimer's disease"	"IRS-related events triggered by IGF1R"	"8"	"0"	"216.7"	"482.7"	"402.2"	"162.4"	"400.1"	"187.8"	"495.1"	"401.6"	"556.8"	"718.0"	"1082.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31939"	"Bifunctional purine biosynthesis protein PURH OS=Homo sapiens OX=9606 GN=ATIC PE=1 SV=3"	"9"	"4"	"6"	"4"	"592"	"64.6"	"6.71"	"867.79"	"8.60"	"3"	"3"	"other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol"	"other molecular function"	"Pf01808, Pf02142"	"471"	"ENSG00000138363"	"ATIC"	"A8K202; E9PBU3; hsa:471; P31939; Q13856; Q53S28"	"One-carbon metabolism"	"Signaling by ALK fusions and activated point mutants; Purine ribonucleoside monophosphate biosynthesis"	"3"	"0"	"49.1"	"286.9"	"215.3"	"48.4"	"218.7"	"72.7"	"112.0"	"93.7"	"125.6"	"177.1"	"321.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P33240"	"Cleavage stimulation factor subunit 2 OS=Homo sapiens OX=9606 GN=CSTF2 PE=1 SV=1"	"7"	"4"	"7"	"4"	"577"	"60.9"	"6.83"	"1303.16"	"8.60"	"4"	"3"	"other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf14304, Pf14327"	"1478"	"ENSG00000101811"	"CSTF2"	"hsa:1478; P33240; Q5H951; Q6LA74; Q8N502"	"mRNA processing"	"tRNA processing in the nucleus; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"6"	"0"	"202.0"	"344.0"	"387.5"	"141.2"	"387.9"	"203.4"	"413.3"	"307.6"	"479.6"	"633.7"	"846.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQ39"	"ATP-dependent RNA helicase DDX50 OS=Homo sapiens OX=9606 GN=DDX50 PE=1 SV=1"	"5"	"3"	"5"	"2"	"737"	"82.5"	"9.17"	"1159.28"	"8.59"	"3"	"2"	""	"plasma membrane;other membranes;nucleus"	"other molecular function"	"Pf00270, Pf00271, Pf08152"	"79009"	"ENSG00000107625"	"DDX50"	"hsa:79009; Q5VX37; Q8WV76; Q9BQ39; Q9BWI8"	""	""	"0"	"0"	"35.8"	"113.2"	"83.9"	"33.8"	"66.2"	"29.7"	"68.2"	"56.8"	"68.1"	"104.5"	"155.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16531"	"DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1"	"6"	"5"	"7"	"5"	"1140"	"126.9"	"5.26"	"1029.00"	"8.57"	"4"	"3"	"cell-cell signaling;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03178, Pf10433"	"1642"	"ENSG00000167986"	"DDB1"	"A6NG77; B2R648; B4DG00; hsa:1642; O15176; Q13289; Q16531; Q58F96"	"Hippo-Merlin signaling dysregulation; Hepatitis B infection; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"Neddylation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; DNA Damage Recognition in GG-NER; Dual Incision in GG-NER"	"14"	"0"	"147.5"	"365.0"	"319.0"	"107.5"	"309.4"	"139.9"	"320.2"	"251.2"	"354.2"	"442.0"	"658.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82970"	"High mobility group nucleosome-binding domain-containing protein 5 OS=Homo sapiens OX=9606 GN=HMGN5 PE=1 SV=1"	"14"	"3"	"6"	"3"	"282"	"31.5"	"4.55"	"986.91"	"8.56"	"3"	"3"	"cell organization and biogenesis;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01101"	"79366"	"ENSG00000198157"	"HMGN5"	"hsa:79366; P82970; Q5JSL1"	""	""	"0"	"0"	"76.2"	"501.3"	"409.2"	"72.8"	"385.3"	"108.6"	"238.0"	"147.9"	"210.2"	"190.3"	"389.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14739"	"Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2"	"5"	"3"	"6"	"3"	"615"	"70.7"	"9.36"	"1008.01"	"8.56"	"3"	"3"	"other metabolic processes;other biological processes"	"other membranes;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01222, Pf09465"	"3930"	"ENSG00000143815"	"LBR"	"B2R5P3; hsa:3930; Q14739; Q14740; Q53GU7; Q59FE6"	"Gastric cancer network 2; ATM signaling in development and disease ; Envelope proteins and their potential roles in EDMD physiopathology; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Cholesterol biosynthesis with skeletal dysplasias; Cholesterol synthesis disorders; Cholesterol metabolism; Enterocyte cholesterol metabolism"	"RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; Initiation of Nuclear Envelope (NE) Reformation; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOD GTPase cycle; RHOC GTPase cycle; Regulation of MECP2 expression and activity; Cholesterol biosynthesis"	"19"	"0"	"117.3"	"496.1"	"447.9"	"77.3"	"315.2"	"124.7"	"282.5"	"207.3"	"377.0"	"403.2"	"718.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82664"	"28S ribosomal protein S10, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS10 PE=1 SV=2"	"16"	"2"	"4"	"2"	"201"	"23.0"	"8.00"	"996.52"	"8.56"	"2"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	""	"Pf00338"	"55173"	"ENSG00000048544"	"MRPS10"	"B2RE89; hsa:55173; P82664; Q9H3E5; Q9NVR3"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"14.1"	"34.8"	"27.0"	"11.2"	"25.2"	"17.8"	"15.8"	"16.2"	"16.7"	"23.0"	"42.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49588"	"Alanine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=AARS1 PE=1 SV=2"	"3"	"3"	"6"	"3"	"968"	"106.7"	"5.53"	"968.00"	"8.55"	"3"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;mitochondrion;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01411, Pf02272, Pf07973"	"16"	"ENSG00000090861"	"AARS1"	"A6NF14; B4DR45; hsa:16; P49588; Q53GV7; Q96FA0"	"IL-18 signaling pathway"	"Cytosolic tRNA aminoacylation"	"2"	"0"	"175.5"	"1293.2"	"987.0"	"96.2"	"858.7"	"247.3"	"305.7"	"216.3"	"294.1"	"367.9"	"825.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6Y7W6"	"GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1"	"2"	"2"	"4"	"2"	"1299"	"150.0"	"5.54"	"1055.83"	"8.55"	"2"	"2"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf02213"	"26058"	"ENSG00000204120"	"GIGYF2"	"A6H8W4; B9EG55; E9PBB0; hsa:26058; O75137; Q6Y7W6; Q7Z2Z8; Q7Z3I2; Q96HU4; Q9NV82"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"58.4"	"117.1"	"114.6"	"44.9"	"100.3"	"70.7"	"93.4"	"83.7"	"124.9"	"125.8"	"179.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HD34"	"LYR motif-containing protein 4 OS=Homo sapiens OX=9606 GN=LYRM4 PE=1 SV=1"	"15"	"2"	"3"	"2"	"91"	"10.8"	"10.73"	"296.33"	"8.52"	"1"	"2"	"cell organization and biogenesis;other metabolic processes"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf05347"	"57128"	"ENSG00000214113"	"LYRM4"	"A8K543; hsa:57128; Q5XKP1; Q9HD34"	"Iron-sulfur cluster biogenesis"	"Mitochondrial iron-sulfur cluster biogenesis"	"2"	"0"	"27.2"	"68.2"	"73.2"	"35.4"	"68.3"	"34.8"	"83.4"	"120.3"	"304.9"	"348.6"	"707.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16698"	"2,4-dienoyl-CoA reductase, mitochondrial OS=Homo sapiens OX=9606 GN=DECR1 PE=1 SV=1"	"10"	"3"	"5"	"3"	"335"	"36.0"	"9.28"	"976.91"	"8.49"	"3"	"2"	"other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf13561"	"1666"	"ENSG00000104325"	"DECR1"	"B7Z6B8; hsa:1666; Q16698; Q2M304; Q93085"	"Fatty acid beta-oxidation; Fatty acid biosynthesis; VEGFA-VEGFR2 signaling"	"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids"	"4"	"0"	"132.6"	"249.7"	"275.4"	"127.0"	"277.1"	"172.8"	"512.4"	"368.8"	"488.7"	"538.8"	"766.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16795"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFA9 PE=1 SV=2"	"5"	"1"	"4"	"1"	"377"	"42.5"	"9.80"	"926.68"	"8.48"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf01370"	"4704"	"ENSG00000139180"	"NDUFA9"	"hsa:4704; Q14076; Q16795; Q2NKX0"	"Electron transport chain: OXPHOS system in mitochondria; Ciliary landscape; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"6"	"0"	"4.4"	"15.2"	"16.0"	"4.3"	"10.3"	"7.8"	"8.4"	"7.3"	"13.1"	"22.7"	"25.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00303"	"Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1"	"10"	"3"	"6"	"3"	"357"	"37.5"	"5.45"	"937.91"	"8.48"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01398, Pf13012"	"8665"	"ENSG00000175390"	"EIF3F"	"A8K0S2; hsa:8665; O00303; Q6IB45; Q8N978"	"Translation factors; VEGFA-VEGFR2 signaling; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"9"	"0"	"147.2"	"261.0"	"253.9"	"130.0"	"247.9"	"172.8"	"245.2"	"177.1"	"241.7"	"293.9"	"413.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NQW7"	"Xaa-Pro aminopeptidase 1 OS=Homo sapiens OX=9606 GN=XPNPEP1 PE=1 SV=3"	"5"	"3"	"6"	"3"	"623"	"69.9"	"5.67"	"1028.48"	"8.47"	"3"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00557, Pf01321, Pf16188, Pf16189"	"7511"	"ENSG00000108039"	"XPNPEP1"	"A8K071; G5E9Y2; G8JLB2; hsa:7511; O15250; Q53EX6; Q8N3Q0; Q96D23; Q9NQW7"	""	""	"0"	"0"	"98.8"	"299.2"	"278.3"	"101.8"	"383.7"	"377.6"	"559.1"	"414.2"	"482.6"	"439.6"	"510.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49720"	"Proteasome subunit beta type-3 OS=Homo sapiens OX=9606 GN=PSMB3 PE=1 SV=2"	"20"	"3"	"6"	"3"	"205"	"22.9"	"6.55"	"1075.30"	"8.45"	"3"	"3"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf00227"	"5691"	"ENSG00000275903; ENSG00000277791"	"PSMB3"	"hsa:5691; P31147; P49720; Q0P6J7; Q96E27"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Regulation of expression of SLITs and ROBOs; The role of GTSE1 in G2/M progression after G2 checkpoint; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; SCF(Skp2)-mediated degradation of p27/p21; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"62"	"0"	"73.2"	"78.1"	"113.0"	"65.6"	"97.4"	"89.8"	"131.1"	"79.8"	"110.4"	"143.3"	"193.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EP5"	"DAZ-associated protein 1 OS=Homo sapiens OX=9606 GN=DAZAP1 PE=1 SV=1"	"10"	"3"	"5"	"3"	"407"	"43.4"	"8.56"	"650.14"	"8.42"	"2"	"3"	"cell cycle OR cell proliferation;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"26528"	"ENSG00000071626"	"DAZAP1"	"hsa:26528; Q96EP5; Q96MJ3; Q9NRR9"	""	""	"0"	"0"	"221.4"	"371.1"	"356.4"	"181.8"	"340.9"	"237.6"	"428.7"	"381.8"	"453.4"	"541.0"	"698.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P45973"	"Chromobox protein homolog 5 OS=Homo sapiens OX=9606 GN=CBX5 PE=1 SV=1"	"18"	"3"	"6"	"3"	"191"	"22.2"	"5.86"	"1131.14"	"8.40"	"3"	"3"	"cell organization and biogenesis;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00385, Pf01393"	"23468"	"ENSG00000094916"	"CBX5"	"B2R8T9; hsa:23468; P45973"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; 22q11.2 copy number variation syndrome"	"Factors involved in megakaryocyte development and platelet production; SUMOylation of chromatin organization proteins; Transcriptional Regulation by E2F6"	"5"	"0"	"82.8"	"215.6"	"233.2"	"73.3"	"206.4"	"138.0"	"275.4"	"160.8"	"208.3"	"256.7"	"380.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A0AVT1"	"Ubiquitin-like modifier-activating enzyme 6 OS=Homo sapiens OX=9606 GN=UBA6 PE=1 SV=1"	"3"	"3"	"6"	"3"	"1052"	"117.9"	"6.14"	"909.52"	"8.39"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00899, Pf09358, Pf10585, Pf16190, Pf16191"	"55236"	"ENSG00000033178"	"UBA6"	"A0AVT1; A6N8M7; B2RAV3; hsa:55236; Q4W5K0; Q6UV21; Q86T78; Q86TC7; Q8N5T3; Q8N9E4; Q9H3T7; Q9NVC9"	""	"Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Antigen processing: Ubiquitination & Proteasome degradation"	"2"	"0"	"102.9"	"280.0"	"257.4"	"97.2"	"236.9"	"120.3"	"142.9"	"118.7"	"160.3"	"226.0"	"360.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5A9"	"YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2"	"5"	"3"	"6"	"2"	"579"	"62.3"	"8.79"	"1006.33"	"8.39"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity"	"Pf04146"	"51441"	"ENSG00000198492"	"YTHDF2"	"A6NKG4; A8K966; B4E1G7; D3DPM8; hsa:51441; Q5VSZ9; Q8TDH0; Q9BUJ5; Q9Y5A9"	""	""	"0"	"0"	"41.7"	"67.6"	"92.0"	"41.9"	"86.3"	"61.9"	"163.0"	"111.8"	"176.4"	"222.5"	"314.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WXX5"	"DnaJ homolog subfamily C member 9 OS=Homo sapiens OX=9606 GN=DNAJC9 PE=1 SV=1"	"20"	"5"	"8"	"5"	"260"	"29.9"	"5.73"	"1694.15"	"8.39"	"5"	"3"	"cell organization and biogenesis;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00226"	"23234"	"ENSG00000213551"	"DNAJC9"	"B2RMW6; hsa:23234; Q8WXX5"	""	""	"0"	"0"	"109.4"	"250.9"	"240.9"	"85.4"	"230.7"	"114.5"	"227.2"	"193.1"	"274.3"	"338.4"	"492.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P48729"	"Casein kinase I isoform alpha OS=Homo sapiens OX=9606 GN=CSNK1A1 PE=1 SV=2"	"9"	"2"	"3"	"2"	"337"	"38.9"	"9.57"	"249.94"	"8.39"	"1"	"2"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"1452"	"ENSG00000113712"	"CSNK1A1"	"D3DQG0; D3DQG1; hsa:1452; P48729; Q4JJA0; Q5U046; Q5U047; Q6FGA2; Q71TU5; Q96HD2; Q9UDK3"	"Alzheimer's disease and miRNA effects; T cell receptor and co-stimulatory signaling; Complement system; Wnt signaling pathway; Wnt/beta-catenin signaling pathway in leukemia; Regulation of Wnt / B-catenin signaling by small molecule compounds; Chromosomal and microsatellite instability in colorectal cancer ; Hedgehog signaling pathway; lncRNA in canonical Wnt signaling and colorectal cancer; Breast cancer pathway; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Influence of laminopathies on Wnt signaling; Overlap between signal transduction pathways contributing to LMNA laminopathies; Pleural mesothelioma; Alzheimer's disease; DYRK1A involvement regarding cell proliferation in brain development"	"Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Activation of SMO; Disassembly of the destruction complex and recruitment of AXIN to the membrane; Beta-catenin phosphorylation cascade; Signaling by GSK3beta mutants; CTNNB1 S33 mutants aren't phosphorylated; CTNNB1 S37 mutants aren't phosphorylated; CTNNB1 S45 mutants aren't phosphorylated; CTNNB1 T41 mutants aren't phosphorylated; APC truncation mutants have impaired AXIN binding; AXIN missense mutants destabilize the destruction complex; Truncations of AMER1 destabilize the destruction complex; Maturation of nucleoprotein"	"32"	"0"	"35.3"	"56.9"	"58.9"	"28.7"	"60.8"	"33.2"	"57.1"	"46.9"	"76.8"	"103.8"	"132.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09661"	"U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2"	"14"	"4"	"6"	"4"	"255"	"28.4"	"8.62"	"914.22"	"8.39"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf14580"	"6627"	"ENSG00000131876"	"SNRPA1"	"B2R5I6; hsa:6627; P09661; Q8TBD2"	"mRNA processing"	"mRNA Splicing - Major Pathway; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	"3"	"0"	"91.9"	"265.0"	"259.4"	"99.9"	"233.1"	"97.5"	"214.1"	"195.4"	"294.3"	"407.2"	"703.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P48735"	"Isocitrate dehydrogenase [NADP], mitochondrial OS=Homo sapiens OX=9606 GN=IDH2 PE=1 SV=2"	"9"	"4"	"7"	"4"	"452"	"50.9"	"8.69"	"1130.02"	"8.36"	"4"	"3"	"other metabolic processes"	"cytosol;mitochondrion;other cytoplasmic organelle"	"other molecular function"	"Pf00180"	"3418"	"ENSG00000182054"	"IDH2"	"B2R6L6; B4DFL2; hsa:3418; P48735; Q96GT3"	"VEGFA-VEGFR2 signaling; Metabolic reprogramming in colon cancer; Cerebral organic acidurias, including diseases; TCA cycle (aka Krebs or citric acid cycle)"	"Transcriptional activation of mitochondrial biogenesis; Citric acid cycle (TCA cycle)"	"6"	"0"	"146.8"	"313.4"	"268.7"	"100.1"	"260.7"	"111.0"	"278.9"	"213.8"	"263.2"	"309.2"	"541.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q02218"	"2-oxoglutarate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=OGDH PE=1 SV=3"	"3"	"3"	"6"	"3"	"1023"	"115.9"	"6.86"	"946.20"	"8.34"	"3"	"3"	"protein metabolism;other metabolic processes;developmental processes"	"other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00676, Pf02779, Pf16078, Pf16870"	"4967"	"ENSG00000105953"	"OGDH"	"B4E2U9; D3DVL0; E9PBM1; hsa:4967; Q02218; Q96DD3; Q9UDX0"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Thiamine metabolic pathways; 7q11.23 copy number variation syndrome; TCA cycle (aka Krebs or citric acid cycle)"	"Lysine catabolism; Glyoxylate metabolism and glycine degradation; Citric acid cycle (TCA cycle)"	"8"	"0"	"67.6"	"190.1"	"187.3"	"72.5"	"183.1"	"85.5"	"159.0"	"139.5"	"161.5"	"263.5"	"336.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75122"	"CLIP-associating protein 2 OS=Homo sapiens OX=9606 GN=CLASP2 PE=1 SV=3"	"3"	"4"	"7"	"3"	"1294"	"141.0"	"8.40"	"1176.98"	"8.32"	"4"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf12348"	"23122"	"ENSG00000163539"	"CLASP2"	"B2RTR1; F5H604; hsa:23122; O75122; Q7L8F6; Q8N6R6; Q9BQT3; Q9BQT4; Q9H7A3; Q9NSZ2"	"7q11.23 copy number variation syndrome"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Role of ABL in ROBO-SLIT signaling"	"8"	"0"	"66.5"	"163.9"	"138.9"	"62.3"	"132.2"	"67.2"	"174.6"	"139.5"	"173.6"	"227.1"	"305.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92522"	"Histone H1.10 OS=Homo sapiens OX=9606 GN=H1-10 PE=1 SV=1"	"12"	"2"	"4"	"2"	"213"	"22.5"	"10.76"	"948.59"	"8.32"	"2"	"2"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00538"	"8971"	"ENSG00000184897"	"H1-10"	"hsa:8971; Q92522"	""	""	"0"	"0"	"76.4"	"137.3"	"144.4"	"62.7"	"149.8"	"84.5"	"179.5"	"160.0"	"205.1"	"275.2"	"350.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49736"	"DNA replication licensing factor MCM2 OS=Homo sapiens OX=9606 GN=MCM2 PE=1 SV=4"	"5"	"4"	"7"	"4"	"904"	"101.8"	"5.52"	"1265.27"	"8.30"	"4"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf12619, Pf14551, Pf17207, Pf17855"	"4171"	"ENSG00000073111"	"MCM2"	"hsa:4171; P49736; Q14577; Q15023; Q8N2V1; Q969W7; Q96AE1; Q9BRM7"	"Cell cycle; Ciliary landscape; G1 to S cell cycle control; DNA replication; 1p36 copy number variation syndrome; 10q11.21q11.23 copy number variation syndrome"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"12"	"0"	"171.6"	"664.2"	"542.8"	"133.6"	"483.3"	"189.3"	"289.4"	"232.3"	"310.9"	"388.5"	"788.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15427"	"Splicing factor 3B subunit 4 OS=Homo sapiens OX=9606 GN=SF3B4 PE=1 SV=1"	"6"	"2"	"5"	"2"	"424"	"44.4"	"8.56"	"639.00"	"8.29"	"1"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00076"	"10262"	"ENSG00000143368"	"SF3B4"	"hsa:10262; Q15427; Q5SZ63"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"3"	"0"	"163.4"	"309.5"	"305.2"	"178.9"	"307.7"	"204.3"	"404.0"	"301.1"	"412.7"	"438.0"	"522.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96CX2"	"BTB/POZ domain-containing protein KCTD12 OS=Homo sapiens OX=9606 GN=KCTD12 PE=1 SV=1"	"9"	"2"	"4"	"2"	"325"	"35.7"	"5.64"	"812.73"	"8.29"	"2"	"2"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf02214"	"115207"	"ENSG00000178695"	"KCTD12"	"hsa:115207; Q96CX2"	""	""	"0"	"0"	"51.7"	"98.1"	"95.6"	"42.5"	"120.0"	"60.2"	"99.1"	"83.1"	"100.0"	"146.4"	"176.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63173"	"60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2"	"47"	"5"	"12"	"4"	"70"	"8.2"	"10.10"	"2268.18"	"8.28"	"5"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01781"	"6169"	"ENSG00000172809"	"RPL38"	"B2R5A8; hsa:6169; P23411; P63173"	"Mesodermal commitment pathway; Mesodermal commitment pathway; Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"16"	"1"	"299.3"	"366.8"	"427.7"	"247.8"	"427.6"	"269.6"	"997.9"	"711.5"	"980.4"	"1225.1"	"1536.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16637"	"Survival motor neuron protein OS=Homo sapiens OX=9606 GN=SMN1 PE=1 SV=1"	"13"	"3"	"5"	"3"	"294"	"31.8"	"6.55"	"636.49"	"8.28"	"2"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06003"	"6606; 6607"	"ENSG00000172062; ENSG00000205571; ENSG00000273772; ENSG00000275349; ENSG00000277773"	"SMN1; SMN2"	"A8K0V4; hsa:6606; hsa:6607; Q13119; Q16637; Q549U5; Q96J51"	"11p11.2 copy number variation syndrome"	"SARS-CoV-2 modulates host translation machinery; snRNP Assembly"	"3"	"0"	"210.7"	"339.6"	"397.3"	"147.1"	"400.6"	"224.2"	"308.6"	"209.6"	"330.2"	"382.0"	"618.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12874"	"Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1"	"5"	"3"	"7"	"2"	"501"	"58.8"	"5.38"	"1179.07"	"8.27"	"3"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf11931, Pf12108, Pf13297, Pf16837"	"10946"	"ENSG00000183431"	"SF3A3"	"D3DPT5; hsa:10946; Q12874; Q15460; Q5VT87"	"Exercise-induced circadian regulation; mRNA processing"	"mRNA Splicing - Major Pathway"	"3"	"1"	"269.4"	"542.1"	"555.8"	"253.5"	"511.6"	"299.3"	"572.2"	"373.0"	"585.0"	"716.8"	"934.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P36959"	"GMP reductase 1 OS=Homo sapiens OX=9606 GN=GMPR PE=1 SV=1"	"9"	"2"	"3"	"1"	"345"	"37.4"	"7.06"	""	"8.27"	""	"2"	"other metabolic processes;stress response"	"cytosol;other cell component"	"other molecular function"	"Pf00478"	"2766"	"ENSG00000137198"	"GMPR"	"hsa:2766; P36959; Q96HQ6"	""	"Purine salvage"	"1"	"0"	"0.0"	"0.0"	"2.2"	"0.0"	"0.0"	"0.0"	"2.5"	"0.0"	"9.0"	"27.7"	"94.1"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q29RF7"	"Sister chromatid cohesion protein PDS5 homolog A OS=Homo sapiens OX=9606 GN=PDS5A PE=1 SV=1"	"3"	"3"	"5"	"3"	"1337"	"150.7"	"7.91"	"529.66"	"8.25"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	""	"Pf20168"	"23244"	"ENSG00000121892"	"PDS5A"	"hsa:23244; Q29RF7; Q2TTR5; Q68DF7; Q8N7J4; Q8NG14; Q9Y4D4"	"Cohesin complex - Cornelia de Lange syndrome"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"5"	"0"	"119.7"	"306.7"	"239.2"	"96.0"	"239.2"	"109.3"	"193.9"	"158.8"	"214.8"	"297.8"	"502.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09497"	"Clathrin light chain B OS=Homo sapiens OX=9606 GN=CLTB PE=1 SV=1"	"11"	"3"	"5"	"3"	"229"	"25.2"	"4.64"	"587.84"	"8.22"	"2"	"3"	"transport"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf01086"	"1212"	"ENSG00000175416"	"CLTB"	"hsa:1212; P09497; Q53Y37; Q6FHW1"	"Ebola virus infection in host; Fragile X syndrome"	"Lysosome Vesicle Biogenesis; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; Formation of annular gap junctions"	"10"	"0"	"161.2"	"368.0"	"374.6"	"162.3"	"402.2"	"191.0"	"300.2"	"229.0"	"352.4"	"495.8"	"721.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q00325"	"Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=2"	"10"	"4"	"7"	"4"	"362"	"40.1"	"9.38"	"1085.99"	"8.21"	"4"	"3"	"transport"	"plasma membrane;other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00153"	"5250"	"ENSG00000075415"	"SLC25A3"	"B3KS34; hsa:5250; Q00325; Q7Z7N7; Q96A03"	""	""	"0"	"0"	"233.1"	"677.1"	"593.8"	"221.1"	"551.3"	"297.3"	"382.4"	"307.8"	"449.5"	"581.6"	"952.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBS4"	"DnaJ homolog subfamily B member 11 OS=Homo sapiens OX=9606 GN=DNAJB11 PE=1 SV=1"	"12"	"3"	"4"	"3"	"358"	"40.5"	"6.18"	"914.64"	"8.20"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"non-structural extracellular;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00226, Pf01556"	"51726"	"ENSG00000090520"	"DNAJB11"	"hsa:51726; Q542Y5; Q542Y9; Q6IAQ8; Q96JC6; Q9UBS4"	"Photodynamic therapy-induced unfolded protein response"	"XBP1(S) activates chaperone genes"	"2"	"0"	"129.7"	"193.1"	"226.7"	"132.5"	"215.9"	"167.0"	"96.9"	"67.4"	"119.7"	"131.3"	"199.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50454"	"Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2"	"8"	"2"	"3"	"2"	"418"	"46.4"	"8.69"	"463.20"	"8.18"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"non-structural extracellular;other membranes;ER/Golgi"	"enzyme regulator activity;other molecular function"	"Pf00079"	"871"	"ENSG00000149257"	"SERPINH1"	"B3KVJ3; hsa:871; P29043; P50454; Q5XPB4; Q6NSJ6; Q8IY96; Q9NP88"	"Endochondral ossification; Type I collagen synthesis in the context of osteogenesis imperfecta; Endochondral ossification with skeletal dysplasias; 15q13.3 copy number variation syndrome"	"Collagen biosynthesis and modifying enzymes"	"5"	"0"	"33.7"	"94.6"	"91.9"	"38.6"	"89.7"	"44.7"	"84.6"	"66.5"	"92.8"	"138.9"	"202.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15437"	"Protein transport protein Sec23B OS=Homo sapiens OX=9606 GN=SEC23B PE=1 SV=2"	"3"	"2"	"8"	"1"	"767"	"86.4"	"6.89"	"1773.67"	"8.17"	"2"	"2"	"cell organization and biogenesis;transport"	"other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00626, Pf04810, Pf04811, Pf04815, Pf08033"	"10483"	"ENSG00000101310"	"SEC23B"	"D3DW33; hsa:10483; Q15437; Q503A9; Q5W183; Q9BS15; Q9BSI2; Q9H1D7"	"Sterol regulatory element-binding proteins (SREBP) signaling"	""	"1"	"0"	"6.7"	"22.7"	"22.9"	"7.9"	"27.1"	"13.0"	"47.5"	"33.1"	"38.2"	"60.2"	"76.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49756"	"RNA-binding protein 25 OS=Homo sapiens OX=9606 GN=RBM25 PE=1 SV=3"	"4"	"2"	"4"	"2"	"843"	"100.1"	"6.32"	"907.92"	"8.17"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf01480"	"58517"	"ENSG00000119707"	"RBM25"	"A0PJL9; B2RNA8; B3KT03; hsa:58517; P49756; Q2TA72; Q5XJ17; Q6P665; Q9H6A1; Q9UEQ5; Q9UIE9"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"5.2"	"24.1"	"25.2"	"2.9"	"17.4"	"5.2"	"19.2"	"17.1"	"33.6"	"62.1"	"94.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P32780"	"General transcription factor IIH subunit 1 OS=Homo sapiens OX=9606 GN=GTF2H1 PE=1 SV=1"	"6"	"3"	"7"	"3"	"548"	"62.0"	"8.66"	"1221.72"	"8.15"	"3"	"2"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus"	"other molecular function"	"Pf03909, Pf08567"	"2965"	"ENSG00000110768; ENSG00000288114"	"GTF2H1"	"B3KXE0; D3DQY2; hsa:2965; P32780; Q6I9Y7; Q9H5K5; Q9NQD9"	"Eukaryotic transcription initiation; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Dual Incision in GG-NER"	"33"	"0"	"100.6"	"326.7"	"310.2"	"88.0"	"259.5"	"131.7"	"307.5"	"558.3"	"1239.0"	"1528.0"	"1935.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7RTV0"	"PHD finger-like domain-containing protein 5A OS=Homo sapiens OX=9606 GN=PHF5A PE=1 SV=1"	"25"	"3"	"5"	"3"	"110"	"12.4"	"8.41"	"594.42"	"8.15"	"2"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03660"	"84844"	"ENSG00000100410"	"PHF5A"	"hsa:84844; Q7RTV0; Q9UH06"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"193.3"	"382.1"	"384.0"	"166.7"	"392.9"	"222.3"	"465.2"	"357.3"	"493.8"	"572.3"	"775.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14136"	"Glial fibrillary acidic protein OS=Homo sapiens OX=9606 GN=GFAP PE=1 SV=1"	"8"	"3"	"5"	"1"	"432"	"49.9"	"5.52"	"607.57"	"8.13"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00038, Pf04732"	"2670"	"ENSG00000131095"	"GFAP"	"A7REI1; B2RD44; D3DX59; E9PAX3; hsa:2670; P14136; Q53H98; Q5D055; Q6ZQS3; Q7Z5J6; Q7Z5J7; Q96KS4; Q96P18; Q9UFD0"	"Neural crest differentiation; Spinal cord injury; Neuroinflammation and glutamatergic signaling"	"Chaperone Mediated Autophagy; Nuclear signaling by ERBB4"	"5"	"0"	"10.7"	"26.3"	"19.1"	"47.6"	"23.7"	"10.7"	"20.4"	"23.6"	"28.4"	"41.6"	"68.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92759"	"General transcription factor IIH subunit 4 OS=Homo sapiens OX=9606 GN=GTF2H4 PE=1 SV=1"	"7"	"3"	"5"	"3"	"462"	"52.2"	"9.04"	"524.39"	"8.10"	"2"	"3"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03849, Pf18307"	"2968"	"ENSG00000213780; ENSG00000221974; ENSG00000226384; ENSG00000233149; ENSG00000234370; ENSG00000236895"	"GTF2H4"	"B4DTJ5; hsa:2968; Q76KU4; Q92759"	"Eukaryotic transcription initiation; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; 11p11.2 copy number variation syndrome"	"RNA Polymerase I Transcription Initiation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Dual Incision in GG-NER; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; Formation of the Early Elongation Complex; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"34"	"0"	"57.8"	"117.3"	"126.5"	"44.4"	"121.8"	"71.9"	"161.2"	"262.2"	"481.4"	"854.3"	"986.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06280"	"Alpha-galactosidase A OS=Homo sapiens OX=9606 GN=GLA PE=1 SV=1"	"9"	"3"	"5"	"3"	"429"	"48.7"	"5.60"	"681.47"	"8.08"	"2"	"3"	"other metabolic processes;other biological processes"	"non-structural extracellular;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf16499, Pf17450"	"2717"	"ENSG00000102393"	"GLA"	"hsa:2717; P06280; Q6LER7"	"Degradation pathway of sphingolipids, including diseases; Ciliary landscape"	"Neutrophil degranulation; Glycosphingolipid metabolism"	"4"	"0"	"37.4"	"221.9"	"182.1"	"36.9"	"167.7"	"50.0"	"90.0"	"74.7"	"90.0"	"129.0"	"217.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UPY8"	"Microtubule-associated protein RP/EB family member 3 OS=Homo sapiens OX=9606 GN=MAPRE3 PE=1 SV=1"	"10"	"2"	"3"	"2"	"281"	"32.0"	"5.54"	"519.64"	"8.07"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf03271"	"22924"	"ENSG00000084764"	"MAPRE3"	"B7WPK5; hsa:22924; O00265; Q6FHB0; Q6FI15; Q9BZP7; Q9BZP8; Q9UPY8"	""	""	"0"	"0"	"22.1"	"54.0"	"70.4"	"24.8"	"70.7"	"27.9"	"101.5"	"86.4"	"227.5"	"404.1"	"572.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14868"	"Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2"	"6"	"3"	"6"	"3"	"501"	"57.1"	"6.55"	"1068.65"	"8.07"	"3"	"3"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00152, Pf01336"	"1615"	"ENSG00000115866"	"DARS1"	"A8K3J2; D3DP77; hsa:1615; P14868; Q2TNI3; Q32Q69; Q53HV4; Q53YC5; Q68CR9; Q9BW52"	"Alanine and aspartate metabolism"	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"3"	"0"	"81.0"	"427.1"	"370.7"	"79.3"	"272.7"	"102.9"	"212.9"	"170.1"	"239.6"	"374.3"	"749.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14839"	"Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2"	"1"	"3"	"5"	"3"	"1912"	"217.9"	"5.86"	"558.77"	"8.05"	"2"	"3"	"cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf00385, Pf00628, Pf06461, Pf06465, Pf08073, Pf08074"	"1108"	"ENSG00000111642"	"CHD4"	"hsa:1108; Q14839; Q8IXZ5"	"Rett syndrome causing genes; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"RNA Polymerase I Transcription Initiation; Potential therapeutics for SARS; HDACs deacetylate histones; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of PTEN gene transcription; Regulation of TP53 Activity through Acetylation; NGF-stimulated transcription"	"9"	"0"	"102.0"	"310.3"	"306.6"	"106.4"	"278.0"	"126.3"	"305.9"	"200.2"	"291.7"	"439.4"	"754.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14974"	"Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2"	"3"	"2"	"4"	"2"	"876"	"97.1"	"4.78"	"341.26"	"8.02"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;signal transduction;other biological processes"	"non-structural extracellular;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00514, Pf03810"	"3837"	"ENSG00000108424"	"KPNB1"	"B7ZAV6; D3DTT3; hsa:3837; Q14637; Q14974; Q53XN2; Q96J27"	"Sterol regulatory element-binding proteins (SREBP) signaling; 22q11.2 copy number variation syndrome"	"Neutrophil degranulation; Assembly of the ORC complex at the origin of replication; Apoptosis induced DNA fragmentation; ISG15 antiviral mechanism; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Nuclear import of Rev protein; Postmitotic nuclear pore complex (NPC) reformation; Interferon alpha/beta signaling; Regulation of cholesterol biosynthesis by SREBP (SREBF); SARS-CoV-1 activates/modulates innate immune responses; Initiation of Nuclear Envelope (NE) Reformation; Inhibition of nitric oxide production"	"15"	"0"	"76.8"	"430.4"	"349.3"	"32.0"	"283.2"	"106.6"	"115.8"	"91.1"	"128.0"	"188.0"	"419.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01082"	"Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2"	"1"	"3"	"5"	"3"	"2364"	"274.4"	"5.57"	"700.07"	"8.02"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00169, Pf00307, Pf00435"	"6711"	"ENSG00000115306"	"SPTBN1"	"B2RP63; hsa:6711; O60837; Q01082; Q16057; Q53R99; Q59ER3; Q8IX99"	"Sudden infant death syndrome (SIDS) susceptibility pathways"	"RHOV GTPase cycle; RHOU GTPase cycle; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; COPI-mediated anterograde transport; Nephrin family interactions; RAF/MAP kinase cascade; NCAM signaling for neurite out-growth; Interaction between L1 and Ankyrins; Signaling by FLT3 fusion proteins"	"11"	"0"	"54.5"	"114.5"	"133.5"	"46.1"	"112.1"	"58.6"	"120.7"	"106.1"	"134.9"	"176.6"	"260.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQP7"	"Mitochondrial genome maintenance exonuclease 1 OS=Homo sapiens OX=9606 GN=MGME1 PE=1 SV=1"	"10"	"2"	"3"	"2"	"344"	"39.4"	"7.68"	"532.38"	"8.00"	"1"	"2"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response"	"mitochondrion"	"other molecular function"	"Pf12705"	"92667"	"ENSG00000125871"	"MGME1"	"B2RDG5; D3DW29; hsa:92667; Q96SW3; Q9BQP7"	"Primary ovarian insufficiency"	""	"1"	"0"	"15.3"	"38.2"	"35.6"	"7.5"	"29.9"	"17.8"	"32.8"	"27.9"	"42.3"	"58.1"	"93.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NYB0"	"Telomeric repeat-binding factor 2-interacting protein 1 OS=Homo sapiens OX=9606 GN=TERF2IP PE=1 SV=1"	"9"	"2"	"4"	"2"	"399"	"44.2"	"4.73"	"720.12"	"7.99"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf08914, Pf11626, Pf16589"	"54386"	"ENSG00000166848"	"TERF2IP"	"B4DQN4; hsa:54386; Q4W4Y2; Q8WYZ3; Q9NWR2; Q9NYB0"	"Splicing factor NOVA regulated synaptic proteins; SARS-CoV-2 mitochondrial chronic oxidative stress and endothelial dysfunction"	"Polymerase switching on the C-strand of the telomere; Meiotic synapsis; Telomere Extension By Telomerase; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; Packaging Of Telomere Ends; DNA Damage/Telomere Stress Induced Senescence; Telomere C-strand synthesis initiation; Removal of the Flap Intermediate from the C-strand"	"16"	"0"	"34.5"	"45.5"	"64.8"	"29.0"	"47.8"	"31.2"	"59.8"	"43.9"	"57.4"	"65.3"	"82.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13561"	"Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4"	"7"	"2"	"4"	"2"	"401"	"44.2"	"5.21"	"833.80"	"7.98"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf04912"	"10540"	"ENSG00000175203"	"DCTN2"	"B2RBK5; hsa:10540; Q13561; Q86YN2; Q9BW17"	""	"MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Recruitment of NuMA to mitotic centrosomes; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"11"	"0"	"87.2"	"274.3"	"232.9"	"73.2"	"184.8"	"81.0"	"106.4"	"77.0"	"118.3"	"162.0"	"266.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82663"	"28S ribosomal protein S25, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS25 PE=1 SV=1"	"20"	"3"	"5"	"3"	"173"	"20.1"	"8.82"	"532.85"	"7.94"	"2"	"3"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf05047"	"64432"	"ENSG00000131368"	"MRPS25"	"B4DFJ5; B4DQG6; hsa:64432; P82663; Q9H7P5"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"14.9"	"33.9"	"31.2"	"12.9"	"26.3"	"24.7"	"18.3"	"4.9"	"15.0"	"20.0"	"24.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13247"	"Serine/arginine-rich splicing factor 6 OS=Homo sapiens OX=9606 GN=SRSF6 PE=1 SV=2"	"7"	"3"	"6"	"2"	"344"	"39.6"	"11.43"	"849.09"	"7.92"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076"	"6431"	"ENSG00000124193"	"SRSF6"	"B7Z6J3; E1P5W6; hsa:6431; Q13244; Q13245; Q13247; Q96J06; Q9UJB8; Q9Y3N7"	"mRNA processing"	"RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing"	"7"	"1"	"202.2"	"584.2"	"552.7"	"164.9"	"529.8"	"242.1"	"692.7"	"509.2"	"622.8"	"755.9"	"1120.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14315"	"Filamin-C OS=Homo sapiens OX=9606 GN=FLNC PE=1 SV=3"	"1"	"2"	"4"	"1"	"2725"	"290.8"	"5.97"	"279.68"	"7.91"	"1"	"2"	"cell organization and biogenesis"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00630"	"2318"	"ENSG00000128591"	"FLNC"	"B2ZZ88; hsa:2318; O95303; Q07985; Q14315; Q9NS12; Q9NYE5; Q9UMR8; Q9Y503"	"Focal adhesion; MAPK signaling pathway; Ebola virus infection in host"	"Cell-extracellular matrix interactions"	"4"	"0"	"6.8"	"33.1"	"26.7"	"6.9"	"26.0"	"7.7"	"20.4"	"16.3"	"22.5"	"29.0"	"47.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IVS2"	"Malonyl-CoA-acyl carrier protein transacylase, mitochondrial OS=Homo sapiens OX=9606 GN=MCAT PE=1 SV=2"	"8"	"2"	"3"	"2"	"390"	"42.9"	"8.72"	"283.97"	"7.91"	"1"	"2"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00698"	"27349"	"ENSG00000100294"	"MCAT"	"B0QY72; hsa:27349; O95510; O95511; Q8IVS2"	"Mitochondrial fatty acid synthesis pathway"	"Mitochondrial Fatty Acid Beta-Oxidation"	"2"	"0"	"37.3"	"83.9"	"81.7"	"32.7"	"83.2"	"50.9"	"158.7"	"126.5"	"221.4"	"373.3"	"602.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63208"	"S-phase kinase-associated protein 1 OS=Homo sapiens OX=9606 GN=SKP1 PE=1 SV=2"	"19"	"2"	"4"	"2"	"163"	"18.6"	"4.54"	"807.19"	"7.90"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf01466, Pf03931"	"6500"	"ENSG00000113558"	"SKP1"	"D3DQ97; D3DQ98; hsa:6500; P34991; P63208; Q8TAY2"	"Cell cycle; TNF-alpha signaling pathway; Breast cancer pathway; Small cell lung cancer; Notch signaling pathway"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; SCF-beta-TrCP mediated degradation of Emi1; Vpu mediated degradation of CD4; Degradation of beta-catenin by the destruction complex; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; NIK-->noncanonical NF-kB signaling; Orc1 removal from chromatin; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Neddylation; SCF(Skp2)-mediated degradation of p27/p21; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Regulation of PLK1 Activity at G2/M Transition; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Circadian Clock; Cyclin D associated events in G1; Regulation of BACH1 activity; MAP3K8 (TPL2)-dependent MAPK1/3 activation; NOTCH1 Intracellular Domain Regulates Transcription; Prolactin receptor signaling; Iron uptake and transport; Nuclear events stimulated by ALK signaling in cancer; Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling"	"38"	"0"	"51.4"	"154.5"	"151.6"	"58.2"	"133.6"	"64.9"	"111.7"	"82.8"	"140.4"	"149.0"	"217.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31930"	"Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3"	"4"	"2"	"5"	"2"	"480"	"52.6"	"6.37"	"669.89"	"7.85"	"1"	"2"	"other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00675, Pf05193"	"7384"	"ENSG00000010256"	"UQCRC1"	"B2R7R8; hsa:7384; P31930; Q96DD2"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex III assembly"	"Respiratory electron transport"	"4"	"0"	"141.0"	"593.8"	"456.6"	"120.3"	"486.4"	"181.4"	"303.0"	"249.9"	"335.2"	"540.8"	"818.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75396"	"Vesicle-trafficking protein SEC22b OS=Homo sapiens OX=9606 GN=SEC22B PE=1 SV=4"	"10"	"1"	"2"	"1"	"215"	"24.6"	"6.92"	""	"7.82"	""	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"6.3"	"50.6"	"36.6"	"7.3"	"35.9"	"10.2"	"10.8"	"12.1"	"14.0"	"16.6"	"31.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P43155"	"Carnitine O-acetyltransferase OS=Homo sapiens OX=9606 GN=CRAT PE=1 SV=5"	"3"	"2"	"5"	"2"	"626"	"70.8"	"8.44"	"1151.50"	"7.82"	"2"	"1"	"other metabolic processes"	"other membranes;cytosol;mitochondrion;ER/Golgi;other cytoplasmic organelle"	"other molecular function"	"Pf00755"	"1384"	"ENSG00000095321"	"CRAT"	"P43155; Q5T952; Q9BW16"	"Fatty acid beta-oxidation"	"Peroxisomal protein import; Beta-oxidation of pristanoyl-CoA"	"3"	"0"	"85.1"	"162.3"	"174.6"	"64.9"	"170.5"	"83.2"	"315.0"	"305.0"	"408.6"	"727.1"	"1421.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15369"	"Elongin-C OS=Homo sapiens OX=9606 GN=ELOC PE=1 SV=1"	"29"	"2"	"4"	"2"	"112"	"12.5"	"4.78"	"684.63"	"7.81"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf03931"	"6921"	"ENSG00000154582"	"ELOC"	"E5RGD9; hsa:6921; Q15369; Q567Q6"	"Dual hijack model of Vif in HIV infection; VEGFA-VEGFR2 signaling; Type 2 papillary renal cell carcinoma; Hijack of ubiquitination by SARS-CoV-2; 11p11.2 copy number variation syndrome"	"Regulation of expression of SLITs and ROBOs; Antigen processing: Ubiquitination & Proteasome degradation; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Vif-mediated degradation of APOBEC3G; Neddylation; Inactivation of CSF3 (G-CSF) signaling; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes"	"22"	"0"	"12.9"	"48.1"	"44.6"	"14.8"	"40.8"	"26.1"	"35.9"	"26.5"	"39.1"	"51.5"	"74.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14566"	"DNA replication licensing factor MCM6 OS=Homo sapiens OX=9606 GN=MCM6 PE=1 SV=1"	"2"	"2"	"4"	"2"	"821"	"92.8"	"5.41"	"854.63"	"7.79"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf14551, Pf17207, Pf17855, Pf18263"	"4175"	"ENSG00000076003"	"MCM6"	"B2R6H2; hsa:4175; Q13504; Q14566; Q99859"	"Cell cycle; Retinoblastoma gene in cancer; Ciliary landscape; G1 to S cell cycle control; DNA replication; 10q11.21q11.23 copy number variation syndrome"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"12"	"0"	"175.3"	"614.1"	"534.1"	"131.5"	"516.2"	"184.0"	"291.9"	"218.9"	"283.4"	"320.4"	"563.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P10768"	"S-formylglutathione hydrolase OS=Homo sapiens OX=9606 GN=ESD PE=1 SV=2"	"12"	"3"	"4"	"3"	"282"	"31.4"	"7.02"	"560.90"	"7.79"	"2"	"2"	"other metabolic processes"	"cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00756"	"2098"	"ENSG00000139684"	"ESD"	"hsa:2098; P10768; Q5TBU8; Q5TBV0; Q5TBV2; Q9BVJ2"	"Phase I biotransformations, non P450"	"Glutathione conjugation"	"2"	"0"	"65.9"	"393.3"	"300.6"	"51.4"	"280.4"	"98.3"	"162.9"	"115.0"	"154.9"	"213.3"	"365.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P98179"	"RNA-binding protein 3 OS=Homo sapiens OX=9606 GN=RBM3 PE=1 SV=1"	"10"	"1"	"4"	"1"	"157"	"17.2"	"8.91"	"767.27"	"7.79"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"translation activity"	"Pf00076"	"5935"	"ENSG00000102317"	"RBM3"	"hsa:5935; P98179"	""	""	"0"	"0"	"161.6"	"252.2"	"160.7"	"118.5"	"137.7"	"102.6"	"256.1"	"268.8"	"296.0"	"346.9"	"546.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15021"	"Condensin complex subunit 1 OS=Homo sapiens OX=9606 GN=NCAPD2 PE=1 SV=3"	"2"	"3"	"4"	"3"	"1401"	"157.1"	"6.61"	"313.94"	"7.79"	"1"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf12717, Pf12922"	"9918"	"ENSG00000010292"	"NCAPD2"	"D3DUR4; hsa:9918; Q15021; Q8N6U3"	""	"Condensation of Prometaphase Chromosomes"	"1"	"0"	"86.9"	"179.0"	"156.9"	"82.9"	"182.7"	"134.6"	"172.6"	"136.0"	"184.7"	"281.5"	"374.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IXB1"	"DnaJ homolog subfamily C member 10 OS=Homo sapiens OX=9606 GN=DNAJC10 PE=1 SV=2"	"3"	"2"	"4"	"2"	"793"	"91.0"	"7.18"	"810.71"	"7.79"	"2"	"2"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"ER/Golgi"	"other molecular function"	"Pf00085, Pf00226"	"54431"	"ENSG00000077232"	"DNAJC10"	"hsa:54431; Q17RJ6; Q3B7W8; Q4ZG06; Q53QT7; Q6UWZ6; Q86T61; Q8IXB1; Q8NC82; Q8TD87; Q96K38; Q96K44; Q96K54; Q9NSY6"	""	""	"0"	"0"	"94.7"	"104.3"	"134.8"	"90.5"	"163.6"	"121.3"	"254.0"	"158.6"	"247.1"	"337.0"	"427.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P27797"	"Calreticulin OS=Homo sapiens OX=9606 GN=CALR PE=1 SV=1"	"13"	"5"	"6"	"5"	"417"	"48.1"	"4.44"	"996.99"	"7.79"	"4"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;extracellular matrix;plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00262"	"811"	"ENSG00000179218"	"CALR"	"hsa:811; P27797; Q6IAT4; Q9UDG2"	"Androgen receptor signaling pathway; Complement system; Photodynamic therapy-induced unfolded protein response; VEGFA-VEGFR2 signaling; GDNF signaling; Calcium regulation in cardiac cells"	"ER-Phagosome pathway; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Scavenging by Class A Receptors; Assembly of Viral Components at the Budding Site; Scavenging by Class F Receptors; ATF6 (ATF6-alpha) activates chaperone genes; Calnexin/calreticulin cycle"	"13"	"0"	"302.6"	"1455.4"	"1276.7"	"204.2"	"1246.4"	"406.4"	"558.9"	"399.1"	"497.5"	"581.9"	"1275.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07741"	"Adenine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=APRT PE=1 SV=2"	"11"	"1"	"4"	"1"	"180"	"19.6"	"6.02"	"854.46"	"7.79"	"1"	"1"	"other metabolic processes;transport;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00156"	"353"	"ENSG00000198931"	"APRT"	"G5E9J2; hsa:353; P07741; Q3KP55; Q68DF9"	""	"Neutrophil degranulation; Purine salvage; Defective APRT disrupts adenine salvage"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQG0"	"Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2"	"2"	"2"	"5"	"2"	"1328"	"148.8"	"9.28"	"813.88"	"7.78"	"2"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04931"	"10514"	"ENSG00000132382"	"MYBBP1A"	"hsa:10514; Q86VM3; Q9BQG0; Q9BW49; Q9P0V5; Q9UF99"	"Energy metabolism"	"B-WICH complex positively regulates rRNA expression"	"2"	"0"	"8.2"	"21.9"	"23.2"	"11.0"	"16.4"	"5.3"	"23.2"	"18.2"	"26.1"	"24.9"	"53.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62304"	"Small nuclear ribonucleoprotein E OS=Homo sapiens OX=9606 GN=SNRPE PE=1 SV=1"	"25"	"2"	"4"	"2"	"92"	"10.8"	"9.44"	"352.48"	"7.77"	"1"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01423"	"6635"	"ENSG00000182004"	"SNRPE"	"B2R5B9; hsa:6635; P08578; P62304; Q15498; Q5BKT2"	"mRNA processing"	"mRNA Splicing - Major Pathway; SARS-CoV-2 modulates host translation machinery; snRNP Assembly; RNA Polymerase II Transcription Termination; mRNA Splicing - Minor Pathway; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"8"	"0"	"38.3"	"100.7"	"94.2"	"41.2"	"78.4"	"37.6"	"89.3"	"72.0"	"110.2"	"152.7"	"207.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z6Z7"	"E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3"	"1"	"2"	"2"	"2"	"4374"	"481.6"	"5.22"	""	"7.76"	""	"2"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00627, Pf00632, Pf02825, Pf06012, Pf06025, Pf14377"	"10075"	"ENSG00000086758"	"HUWE1"	"hsa:10075; O15029; Q4G2Z2; Q5H961; Q6P4D0; Q7Z6Z7; Q8NG67; Q9BUI0; Q9HCJ4; Q9NSL6; Q9P0A9"	""	"Antigen processing: Ubiquitination & Proteasome degradation; Neutrophil degranulation"	"2"	"0"	"5.2"	"20.9"	"15.7"	"11.4"	"16.5"	"5.4"	"19.6"	"10.4"	"19.9"	"24.5"	"24.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49755"	"Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2"	"16"	"3"	"6"	"3"	"219"	"25.0"	"7.44"	"1084.84"	"7.75"	"3"	"3"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"transporter activity;other molecular function"	"Pf01105"	"10972"	"ENSG00000170348"	"TMED10"	"B2R605; hsa:10972; P49755; Q15602; Q16536; Q86TC2; Q86TS5"	"mRNA processing"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport; COPII-mediated vesicle transport; Cargo concentration in the ER"	"5"	"0"	"20.6"	"103.1"	"86.8"	"20.9"	"72.7"	"23.8"	"39.5"	"37.7"	"44.3"	"74.6"	"128.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UPY6"	"Wiskott-Aldrich syndrome protein family member 3 OS=Homo sapiens OX=9606 GN=WASF3 PE=1 SV=2"	"5"	"2"	"4"	"2"	"502"	"55.3"	"6.43"	"891.77"	"7.75"	"2"	"2"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02205"	"10810"	"ENSG00000132970"	"WASF3"	"hsa:10810; O94974; Q86VQ2; Q9UPY6"	""	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; VEGFA-VEGFR2 Pathway; RAC1 GTPase cycle"	"5"	"0"	"20.0"	"24.6"	"36.6"	"19.8"	"38.6"	"34.2"	"52.3"	"38.0"	"55.8"	"68.3"	"78.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01518"	"Adenylyl cyclase-associated protein 1 OS=Homo sapiens OX=9606 GN=CAP1 PE=1 SV=5"	"12"	"4"	"5"	"4"	"475"	"51.9"	"8.06"	"1174.42"	"7.75"	"3"	"2"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01213, Pf08603"	"10487"	"ENSG00000131236"	"CAP1"	"hsa:10487; Q01518; Q53HR7; Q5T0S1; Q5T0S2; Q6I9U6"	"Angiopoietin-like protein 8 regulatory pathway; Insulin signaling; Complement system in neuronal development and plasticity; Opioid receptor pathways"	"Neutrophil degranulation; Platelet degranulation ; Role of ABL in ROBO-SLIT signaling"	"7"	"0"	"121.5"	"287.0"	"285.6"	"84.8"	"291.2"	"127.5"	"251.8"	"179.7"	"223.5"	"297.1"	"473.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NQ50"	"39S ribosomal protein L40, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL40 PE=1 SV=1"	"14"	"2"	"4"	"2"	"206"	"24.5"	"9.63"	"824.75"	"7.74"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	""	"Pf09812"	"64976"	"ENSG00000185608"	"MRPL40"	"B3KVZ7; hsa:64976; O95134; Q9NQ50"	"22q11.2 copy number variation syndrome"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"4"	"0"	"44.0"	"118.9"	"117.2"	"49.0"	"117.0"	"60.5"	"111.8"	"83.9"	"122.7"	"184.8"	"272.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14744"	"Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4"	"4"	"3"	"5"	"3"	"637"	"72.6"	"6.29"	"573.19"	"7.71"	"2"	"3"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05185, Pf17285, Pf17286"	"10419"	"ENSG00000100462"	"PRMT5"	"A8MTP3; A8MZ91; B4DX49; B4DY30; B5BU10; D3DS33; E2QRE7; hsa:10419; O14744; Q6IBR1; Q9UKH1"	"Transcription co-factors SKI and SKIL protein partners; Nitric oxide metabolism in cystic fibrosis"	"RMTs methylate histone arginines; snRNP Assembly; Regulation of TP53 Activity through Methylation"	"5"	"0"	"266.7"	"752.9"	"714.8"	"242.6"	"596.6"	"270.2"	"483.5"	"360.6"	"470.6"	"638.3"	"1081.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14554"	"Protein disulfide-isomerase A5 OS=Homo sapiens OX=9606 GN=PDIA5 PE=1 SV=1"	"7"	"3"	"4"	"3"	"519"	"59.6"	"7.91"	"460.21"	"7.69"	"1"	"3"	"other metabolic processes;other biological processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf00085"	"10954"	"ENSG00000065485"	"PDIA5"	"D3DN95; hsa:10954; Q14554; Q9BV43"	""	"XBP1(S) activates chaperone genes"	"1"	"0"	"41.3"	"63.2"	"77.9"	"29.6"	"65.7"	"58.4"	"80.3"	"80.1"	"188.4"	"452.7"	"776.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q08945"	"FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1"	"3"	"2"	"6"	"2"	"709"	"81.0"	"6.87"	"914.05"	"7.69"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00505, Pf03531, Pf08512, Pf17292"	"6749"	"ENSG00000149136"	"SSRP1"	"hsa:6749; Q08945; Q5BJG8"	""	"Regulation of TP53 Activity through Phosphorylation; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes"	"12"	"0"	"179.3"	"390.3"	"403.6"	"154.6"	"386.8"	"212.2"	"779.6"	"453.3"	"660.8"	"854.0"	"1522.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TAM2"	"Tetratricopeptide repeat protein 8 OS=Homo sapiens OX=9606 GN=TTC8 PE=1 SV=2"	"6"	"2"	"4"	"2"	"541"	"61.5"	"6.80"	"584.78"	"7.69"	"2"	"2"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf13176, Pf13432"	"123016"	"ENSG00000165533"	"TTC8"	"A6NFG2; B3KWA5; hsa:123016; Q67B97; Q86SY0; Q86TV9; Q86U26; Q8NDH9; Q8TAM2; Q96DG8"	"Ciliary landscape; Genes related to primary cilium development (based on CRISPR); Joubert syndrome; Ciliopathies; Bardet-Biedl syndrome"	"BBSome-mediated cargo-targeting to cilium"	"6"	"0"	"44.2"	"98.4"	"98.1"	"35.6"	"99.8"	"45.6"	"137.3"	"147.3"	"294.7"	"384.6"	"525.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UEE9"	"Craniofacial development protein 1 OS=Homo sapiens OX=9606 GN=CFDP1 PE=1 SV=1"	"14"	"3"	"5"	"3"	"299"	"33.6"	"4.81"	"1203.56"	"7.67"	"2"	"2"	"cell adhesion;cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	""	"Pf07572"	"10428"	"ENSG00000153774"	"CFDP1"	"hsa:10428; O00393; O00404; Q9UEE9; Q9UEF0; Q9UEF1; Q9UEF8"	""	""	"0"	"0"	"141.1"	"353.2"	"338.8"	"93.8"	"306.6"	"156.3"	"314.9"	"172.2"	"251.2"	"311.3"	"455.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NYU2"	"UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3"	"2"	"3"	"5"	"3"	"1555"	"177.1"	"5.63"	"660.75"	"7.63"	"2"	"3"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"ER/Golgi;other cell component"	"other molecular function"	"Pf06427, Pf18400, Pf18401, Pf18402, Pf18403, Pf18404"	"56886"	"ENSG00000136731"	"UGGT1"	"hsa:56886; Q53QP2; Q53SL3; Q8IW30; Q9H8I4; Q9NYU2"	"IL-18 signaling pathway"	"ER Quality Control Compartment (ERQC)"	"2"	"0"	"230.6"	"377.3"	"407.6"	"201.1"	"409.0"	"249.6"	"406.4"	"315.8"	"431.5"	"514.9"	"646.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04181"	"Ornithine aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OAT PE=1 SV=1"	"9"	"2"	"3"	"2"	"439"	"48.5"	"7.03"	"522.87"	"7.63"	"1"	"2"	"other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00202"	"4942"	"ENSG00000065154"	"OAT"	"D3DRF0; hsa:4942; P04181; Q16068; Q16069; Q68CS0; Q6IAV9; Q9UD03"	"Amino acid metabolism; 22q11.2 copy number variation syndrome; Creatine pathway"	"Glutamate and glutamine metabolism"	"4"	"0"	"17.6"	"217.9"	"133.0"	"18.0"	"125.7"	"27.0"	"22.8"	"15.2"	"17.5"	"26.5"	"84.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94761"	"ATP-dependent DNA helicase Q4 OS=Homo sapiens OX=9606 GN=RECQL4 PE=1 SV=2"	"1"	"2"	"3"	"2"	"1208"	"133.0"	"8.09"	"580.20"	"7.58"	"1"	"2"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf11719"	"9401"	"ENSG00000160957"	"RECQL4"	"A0A087WZ30; hsa:9401; O94761; Q3Y424; Q96DW2; Q96F55"	"Primary ovarian insufficiency"	""	"1"	"0"	"4.5"	"10.1"	"9.7"	"2.4"	"11.9"	"4.6"	"15.5"	"13.1"	"15.6"	"14.7"	"21.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4Z0"	"U6 snRNA-associated Sm-like protein LSm4 OS=Homo sapiens OX=9606 GN=LSM4 PE=1 SV=1"	"24"	"4"	"7"	"4"	"139"	"15.3"	"9.99"	"1411.45"	"7.57"	"4"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01423"	"25804"	"ENSG00000130520"	"LSM4"	"hsa:25804; Q9Y4Z0"	"Ciliary landscape"	"mRNA Splicing - Major Pathway; mRNA decay by 5' to 3' exoribonuclease"	"3"	"0"	"102.0"	"278.1"	"985.9"	"81.8"	"187.2"	"106.8"	"216.2"	"178.7"	"241.7"	"305.9"	"437.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30041"	"Peroxiredoxin-6 OS=Homo sapiens OX=9606 GN=PRDX6 PE=1 SV=3"	"16"	"4"	"6"	"4"	"224"	"25.0"	"6.38"	"983.07"	"7.55"	"3"	"3"	"other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00578, Pf10417"	"9588"	"ENSG00000117592"	"PRDX6"	"A8JZY7; hsa:9588; P30041; P32077; Q5TAH4; Q5ZEZ8"	"Nuclear receptors meta-pathway; NRF2 pathway; VEGFA-VEGFR2 signaling"	"Neutrophil degranulation; Detoxification of Reactive Oxygen Species"	"5"	"0"	"307.1"	"2009.7"	"1603.9"	"156.4"	"1287.9"	"367.5"	"651.6"	"481.3"	"652.8"	"722.1"	"1688.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P0L0"	"Vesicle-associated membrane protein-associated protein A OS=Homo sapiens OX=9606 GN=VAPA PE=1 SV=3"	"4"	"1"	"3"	"1"	"249"	"27.9"	"8.62"	"286.31"	"7.54"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00635"	"9218"	"ENSG00000101558"	"VAPA"	"A6NDZ0; D3DUI3; hsa:9218; O75453; Q5U0E7; Q9P0L0; Q9UBZ2"	"Exercise-induced circadian regulation; Cholesterol metabolism"	"Neutrophil degranulation; Insertion of tail-anchored proteins into the endoplasmic reticulum membrane; Sphingolipid de novo biosynthesis"	"5"	"0"	"158.9"	"470.6"	"515.4"	"152.0"	"462.3"	"208.8"	"257.4"	"185.5"	"331.4"	"393.1"	"767.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31689"	"DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2"	"6"	"1"	"2"	"1"	"397"	"44.8"	"7.08"	""	"7.47"	""	"1"	"stress response;transport;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00226, Pf00684, Pf01556"	"3301"	"ENSG00000086061"	"DNAJA1"	"hsa:3301; P31689; Q5T7Q0; Q86TL9"	"VEGFA-VEGFR2 signaling; Exercise-induced circadian regulation"	"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P45974"	"Ubiquitin carboxyl-terminal hydrolase 5 OS=Homo sapiens OX=9606 GN=USP5 PE=1 SV=2"	"6"	"5"	"8"	"5"	"858"	"95.7"	"5.03"	"1860.15"	"7.46"	"5"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle"	"other molecular function"	"Pf00443, Pf00627, Pf02148, Pf17807"	"8078"	"ENSG00000111667"	"USP5"	"D3DUS7; D3DUS8; hsa:8078; P45974; Q96J22"	"IL-18 signaling pathway"	"Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Ub-specific processing proteases"	"3"	"0"	"263.3"	"703.7"	"713.3"	"237.7"	"702.0"	"279.3"	"432.4"	"377.5"	"506.0"	"676.5"	"960.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49792"	"E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2"	"1"	"3"	"5"	"2"	"3224"	"358.0"	"6.20"	"599.37"	"7.45"	"2"	"3"	"protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00160, Pf00638, Pf00641, Pf12185"	"5903"	"ENSG00000153201"	"RANBP2"	"hsa:5903; P49792; Q13074; Q15280; Q53TE2; Q59FH7"	""	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; HCMV Late Events; HCMV Early Events; Transcriptional regulation by small RNAs; tRNA processing in the nucleus; Rev-mediated nuclear export of HIV RNA; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); SARS-CoV-2 activates/modulates innate and adaptive immune responses; Signaling by ALK fusions and activated point mutants"	"35"	"0"	"16.4"	"63.9"	"56.2"	"21.1"	"53.2"	"22.4"	"35.5"	"32.1"	"61.5"	"96.5"	"121.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBQ5"	"Eukaryotic translation initiation factor 3 subunit K OS=Homo sapiens OX=9606 GN=EIF3K PE=1 SV=1"	"17"	"3"	"4"	"3"	"218"	"25.0"	"4.93"	"747.35"	"7.44"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf10075"	"27335"	"ENSG00000178982; ENSG00000282986"	"EIF3K"	"A8K0I9; B7ZAM9; hsa:27335; Q96IQ0; Q9UBQ5; Q9Y6D1"	""	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"6"	"0"	"188.5"	"432.1"	"460.9"	"179.8"	"403.6"	"199.9"	"397.0"	"329.9"	"487.1"	"572.5"	"841.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P00491"	"Purine nucleoside phosphorylase OS=Homo sapiens OX=9606 GN=PNP PE=1 SV=2"	"11"	"2"	"4"	"2"	"289"	"32.1"	"6.95"	"665.09"	"7.42"	"2"	"2"	"other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf01048"	"4860"	"ENSG00000198805"	"PNP"	"B2R8S5; D3DS00; hsa:4860; P00491; Q15160; Q5PZ03"	"VEGFA-VEGFR2 signaling"	"Neutrophil degranulation; Purine catabolism; Ribavirin ADME; Purine salvage; Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine"	"6"	"0"	"17.6"	"54.4"	"56.0"	"18.8"	"45.9"	"18.3"	"41.4"	"36.4"	"44.2"	"62.4"	"92.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N163"	"Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2"	"3"	"2"	"4"	"2"	"923"	"102.8"	"5.22"	"716.19"	"7.42"	"2"	"2"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytoskeleton;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf14443, Pf14444, Pf19256, Pf19257"	"57805"	"ENSG00000158941"	"CCAR2"	"A6NL03; B2RB79; D3DSR6; hsa:57805; Q6P0Q9; Q8N163; Q8N3G7; Q8N8M1; Q8TF34; Q9H9Q9; Q9HD12; Q9NT55"	""	"Regulation of HSF1-mediated heat shock response"	"1"	"0"	"34.3"	"53.9"	"57.6"	"29.6"	"54.4"	"38.0"	"86.7"	"68.8"	"110.2"	"172.5"	"211.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09012"	"U1 small nuclear ribonucleoprotein A OS=Homo sapiens OX=9606 GN=SNRPA PE=1 SV=3"	"9"	"3"	"5"	"2"	"282"	"31.3"	"9.83"	"641.14"	"7.42"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6626"	"ENSG00000077312"	"SNRPA"	"hsa:6626; P09012"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"1"	"264.7"	"651.5"	"620.6"	"208.6"	"559.8"	"264.0"	"698.4"	"526.4"	"866.1"	"1203.6"	"1704.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6GYQ0"	"Ral GTPase-activating protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=RALGAPA1 PE=1 SV=1"	"2"	"3"	"4"	"3"	"2036"	"229.7"	"6.19"	"365.40"	"7.41"	"1"	"3"	"other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02145, Pf20412"	"253959"	"ENSG00000174373"	"RALGAPA1"	"A6NMA4; B9EK38; C5NU19; hsa:253959; O94960; Q6GYP9; Q6GYQ0; Q6ZT23; Q86YF3; Q86YF5; Q8ND69"	""	"RHOH GTPase cycle"	"1"	"0"	"49.9"	"89.9"	"112.4"	"55.6"	"106.8"	"71.7"	"128.3"	"108.0"	"361.6"	"585.7"	"631.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92890"	"Ubiquitin recognition factor in ER-associated degradation protein 1 OS=Homo sapiens OX=9606 GN=UFD1 PE=1 SV=3"	"8"	"2"	"4"	"2"	"307"	"34.5"	"6.70"	"764.37"	"7.40"	"2"	"2"	"protein metabolism;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf03152"	"7353"	"ENSG00000070010"	"UFD1"	"A8MW31; hsa:7353; Q92890; Q9Y5N0"	"22q11.2 copy number variation syndrome"	"Ub-specific processing proteases; Neddylation; KEAP1-NFE2L2 pathway; Translesion Synthesis by POLH"	"5"	"0"	"72.1"	"138.7"	"142.5"	"81.9"	"131.3"	"81.4"	"145.6"	"124.9"	"181.8"	"180.3"	"224.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P0C7P4"	"Putative cytochrome b-c1 complex subunit Rieske-like protein 1 OS=Homo sapiens OX=9606 GN=UQCRFS1P1 PE=5 SV=1"	"8"	"3"	"4"	"3"	"283"	"30.8"	"8.87"	"324.24"	"7.38"	"1"	"3"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00355, Pf02921, Pf09165"	""	""	"UQCRFS1P1"	"P0C7P4"	""	""	"0"	"0"	"656.6"	"1077.4"	"903.2"	"396.1"	"829.3"	"453.8"	"698.3"	"635.1"	"975.3"	"1279.0"	"1615.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P21953"	"2-oxoisovalerate dehydrogenase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=BCKDHB PE=1 SV=2"	"10"	"3"	"5"	"3"	"392"	"43.1"	"6.29"	"1170.57"	"7.34"	"3"	"2"	"other metabolic processes;other biological processes"	"mitochondrion;nucleus"	"other molecular function"	"Pf02779, Pf02780"	"594"	"ENSG00000083123"	"BCKDHB"	"hsa:594; P21953; Q5T2J3; Q9BQL0"	"Primary ovarian insufficiency"	"Glyoxylate metabolism and glycine degradation; Branched-chain amino acid catabolism"	"3"	"0"	"133.3"	"377.7"	"394.0"	"149.5"	"352.2"	"153.7"	"312.1"	"235.9"	"287.8"	"408.4"	"564.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UFW8"	"CGG triplet repeat-binding protein 1 OS=Homo sapiens OX=9606 GN=CGGBP1 PE=1 SV=2"	"12"	"2"	"4"	"2"	"167"	"18.8"	"8.95"	"611.31"	"7.31"	"2"	"2"	"cell organization and biogenesis;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	""	"8545"	"ENSG00000163320"	"CGGBP1"	"D3DU38; hsa:8545; O15183; Q9UFW8"	""	""	"0"	"0"	"82.7"	"120.3"	"110.1"	"70.6"	"139.1"	"83.3"	"213.2"	"132.1"	"198.0"	"235.6"	"358.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NRX1"	"RNA-binding protein PNO1 OS=Homo sapiens OX=9606 GN=PNO1 PE=1 SV=1"	"7"	"1"	"4"	"1"	"252"	"27.9"	"9.73"	"911.71"	"7.30"	"1"	"1"	"other biological processes"	"cytosol;nucleus;other cell component"	""	""	"56902"	"ENSG00000115946"	"PNO1"	"A8K6Q0; hsa:56902; Q53G13; Q8WVB8; Q9NRX1"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13098"	"COP9 signalosome complex subunit 1 OS=Homo sapiens OX=9606 GN=GPS1 PE=1 SV=4"	"5"	"2"	"4"	"2"	"491"	"55.5"	"6.74"	"893.12"	"7.29"	"2"	"2"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf01399, Pf10602"	"2873"	"ENSG00000169727"	"GPS1"	"hsa:2873; Q13098; Q8NA10; Q9BWL1"	""	"Neddylation; RHOBTB1 GTPase cycle; Cargo recognition for clathrin-mediated endocytosis; Formation of TC-NER Pre-Incision Complex; DNA Damage Recognition in GG-NER"	"5"	"0"	"90.1"	"254.3"	"263.4"	"85.6"	"256.3"	"107.1"	"159.9"	"100.0"	"137.2"	"184.2"	"318.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13868"	"Exosome complex component RRP4 OS=Homo sapiens OX=9606 GN=EXOSC2 PE=1 SV=2"	"9"	"2"	"4"	"2"	"293"	"32.8"	"7.50"	"722.35"	"7.28"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf14382, Pf15985"	"23404"	"ENSG00000130713"	"EXOSC2"	"A3KFL3; A3KFL4; B4DKK6; hsa:23404; Q13868; Q9NUY4"	"Ciliary landscape"	"Major pathway of rRNA processing in the nucleolus and cytosol; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	"7"	"0"	"76.6"	"206.0"	"214.1"	"71.5"	"181.0"	"79.5"	"182.6"	"127.1"	"182.6"	"231.0"	"358.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75400"	"Pre-mRNA-processing factor 40 homolog A OS=Homo sapiens OX=9606 GN=PRPF40A PE=1 SV=2"	"3"	"2"	"3"	"2"	"957"	"108.7"	"7.56"	"466.84"	"7.27"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	"Pf00397, Pf01846"	"55660"	"ENSG00000196504"	"PRPF40A"	"hsa:55660; O43856; O75400; O75404; Q8TBQ1; Q9H782; Q9NWU9; Q9P0Q2; Q9Y5A8"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"70.3"	"139.3"	"131.3"	"58.2"	"147.1"	"82.0"	"133.3"	"84.8"	"136.8"	"166.5"	"211.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P1J9"	"Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1"	"6"	"4"	"7"	"4"	"531"	"60.5"	"9.61"	"1136.98"	"7.26"	"4"	"3"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf05179, Pf16050"	"79577"	"ENSG00000134371"	"CDC73"	"A6NLZ8; B2RBR2; hsa:79577; Q6P1J9; Q6PK51; Q96A07; Q9H245; Q9H5L7"	"Endoderm differentiation"	"Hedgehog 'on' state; E3 ubiquitin ligases ubiquitinate target proteins; Formation of the beta-catenin:TCF transactivating complex; Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events"	"7"	"0"	"118.2"	"190.3"	"211.2"	"122.5"	"232.0"	"125.7"	"717.3"	"564.4"	"730.8"	"909.9"	"1167.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P1N9"	"Putative deoxyribonuclease TATDN1 OS=Homo sapiens OX=9606 GN=TATDN1 PE=1 SV=2"	"8"	"2"	"2"	"2"	"297"	"33.6"	"6.96"	""	"7.25"	""	"2"	"DNA metabolism"	"nucleus"	"other molecular function"	"Pf01026"	"83940"	"ENSG00000147687"	"TATDN1"	"B2R5J0; hsa:83940; Q6P1N9; Q8TD02; Q9BY40"	""	""	"0"	"0"	"54.0"	"128.6"	"126.5"	"54.7"	"155.9"	"77.9"	"114.6"	"110.6"	"160.9"	"396.0"	"1006.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07919"	"Cytochrome b-c1 complex subunit 6, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRH PE=1 SV=2"	"14"	"2"	"5"	"2"	"91"	"10.7"	"4.44"	"485.79"	"7.22"	"2"	"2"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf02320"	"7388"	"ENSG00000173660"	"UQCRH"	"B2R4V9; D3DQ18; hsa:7388; P07919; Q5TDF6; Q6LDB8; Q9BQ91"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex III assembly"	"Respiratory electron transport"	"4"	"0"	"490.1"	"1084.6"	"1013.1"	"304.4"	"899.6"	"443.5"	"610.1"	"437.8"	"638.4"	"798.3"	"1374.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15212"	"Prefoldin subunit 6 OS=Homo sapiens OX=9606 GN=PFDN6 PE=1 SV=1"	"22"	"3"	"7"	"3"	"129"	"14.6"	"8.88"	"1249.75"	"7.20"	"3"	"2"	"cell organization and biogenesis;other biological processes"	"other cell component"	"other molecular function"	"Pf01920"	"10471"	"ENSG00000204220; ENSG00000206283; ENSG00000224782; ENSG00000235692; ENSG00000237335"	"PFDN6"	"hsa:10471; O15212"	"Cellular proteostasis"	"Prefoldin mediated transfer of substrate  to CCT/TriC"	"2"	"0"	"53.3"	"191.3"	"168.5"	"37.3"	"127.6"	"51.4"	"106.5"	"81.2"	"117.2"	"155.4"	"321.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKD2"	"mRNA turnover protein 4 homolog OS=Homo sapiens OX=9606 GN=MRTO4 PE=1 SV=2"	"14"	"2"	"3"	"2"	"239"	"27.5"	"8.29"	"338.78"	"7.19"	"1"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf00466, Pf17777"	"51154"	"ENSG00000053372"	"MRTO4"	"B3KNB3; hsa:51154; Q5TG55; Q96SS6; Q9BPV9; Q9UKD2"	""	""	"0"	"0"	"49.4"	"95.8"	"114.5"	"56.8"	"100.3"	"58.5"	"130.3"	"83.3"	"120.0"	"133.2"	"217.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P48426"	"Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha OS=Homo sapiens OX=9606 GN=PIP4K2A PE=1 SV=2"	"8"	"2"	"4"	"1"	"406"	"46.2"	"6.99"	"780.94"	"7.19"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf01504"	"5305"	"ENSG00000150867"	"PIP4K2A"	"B0YJ66; B4DGX2; D3DRV1; hsa:5305; P48426; P53807; Q5VUX3"	"Regulation of actin cytoskeleton; G13 signaling pathway"	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Synthesis of PIPs at the plasma membrane; PI5P Regulates TP53 Acetylation; Synthesis of PIPs in the nucleus"	"6"	"0"	"32.3"	"64.1"	"59.6"	"24.4"	"52.7"	"33.3"	"46.9"	"60.3"	"90.2"	"210.4"	"406.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NYJ1"	"Cytochrome c oxidase assembly factor 4 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=COA4 PE=1 SV=2"	"20"	"2"	"5"	"2"	"87"	"10.1"	"6.04"	"954.23"	"7.17"	"2"	"1"	"cell organization and biogenesis"	"mitochondrion"	""	""	"51287"	"ENSG00000181924"	"COA4"	"B2RAA0; hsa:51287; Q69YU4; Q9NYJ1"	""	"Mitochondrial protein import"	"1"	"0"	"31.2"	"75.2"	"83.7"	"29.2"	"91.1"	"50.5"	"82.2"	"48.0"	"87.5"	"103.6"	"124.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NP97"	"Dynein light chain roadblock-type 1 OS=Homo sapiens OX=9606 GN=DYNLRB1 PE=1 SV=3"	"35"	"3"	"7"	"3"	"96"	"10.9"	"7.25"	"1578.73"	"7.16"	"2"	"2"	"other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03259"	"83658"	"ENSG00000125971"	"DYNLRB1"	"B1AKR5; hsa:83658; Q5TC72; Q96IV3; Q9NP97; Q9NQM2"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein; 3q29 copy number variation syndrome"	"Intraflagellar transport"	"4"	"0"	"256.8"	"460.4"	"557.7"	"253.8"	"486.5"	"325.3"	"517.2"	"373.3"	"554.9"	"611.0"	"893.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14874"	"[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial OS=Homo sapiens OX=9606 GN=BCKDK PE=1 SV=2"	"8"	"2"	"3"	"2"	"412"	"46.3"	"8.82"	"389.62"	"7.16"	"1"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"mitochondrion"	"kinase activity;other molecular function"	"Pf02518, Pf10436"	"10295"	"ENSG00000103507"	"BCKDK"	"A8MY43; hsa:10295; O14874; Q6FGL4; Q96G95; Q96IN5"	"Thiamine metabolic pathways"	"Branched-chain amino acid catabolism"	"2"	"0"	"21.1"	"59.4"	"56.4"	"21.4"	"56.9"	"26.4"	"146.1"	"116.2"	"128.3"	"151.0"	"169.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08621"	"U1 small nuclear ribonucleoprotein 70 kDa OS=Homo sapiens OX=9606 GN=SNRNP70 PE=1 SV=2"	"6"	"3"	"5"	"3"	"437"	"51.5"	"9.94"	"1120.50"	"7.14"	"3"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf12220"	"6625"	"ENSG00000104852"	"SNRNP70"	"B3KUA3; hsa:6625; P08621; P78493; P78494; Q15364; Q15686; Q15687; Q15689; Q99377; Q9UE45; Q9UE46; Q9UE47; Q9UE48; Q9UFQ6"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"126.7"	"257.4"	"253.2"	"112.3"	"243.9"	"132.0"	"319.6"	"266.2"	"407.3"	"551.5"	"855.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3D9"	"28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2"	"9"	"2"	"6"	"2"	"190"	"21.8"	"8.90"	"887.83"	"7.08"	"2"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf10484"	"51649"	"ENSG00000181610"	"MRPS23"	"B2R6V3; hsa:51649; Q96Q24; Q9BWH8; Q9P053; Q9Y3D9"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"147.6"	"328.8"	"316.9"	"144.5"	"312.2"	"172.3"	"270.4"	"192.8"	"293.5"	"382.6"	"563.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92974"	"Rho guanine nucleotide exchange factor 2 OS=Homo sapiens OX=9606 GN=ARHGEF2 PE=1 SV=4"	"2"	"2"	"4"	"2"	"986"	"111.5"	"7.27"	"949.41"	"7.08"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00621, Pf17838"	"9181"	"ENSG00000116584"	"ARHGEF2"	"D3DVA6; hsa:9181; O75142; Q15079; Q5VY92; Q8TDA3; Q8WUG4; Q92974; Q9H023"	"Pathogenic Escherichia coli infection"	"RHOA GTPase cycle; NRAGE signals death through JNK; G alpha (12/13) signalling events; RHOB GTPase cycle"	"5"	"0"	"77.4"	"123.7"	"138.4"	"61.4"	"131.3"	"80.8"	"237.9"	"174.9"	"267.7"	"307.5"	"387.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NR31"	"GTP-binding protein SAR1a OS=Homo sapiens OX=9606 GN=SAR1A PE=1 SV=1"	"8"	"1"	"4"	"1"	"198"	"22.4"	"6.68"	"852.03"	"7.08"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf00025"	"56681"	"ENSG00000079332"	"SAR1A"	"B4DQ19; hsa:56681; Q9NR31"	"Sterol regulatory element-binding proteins (SREBP) signaling"	""	"1"	"0"	"131.7"	"171.9"	"185.3"	"88.6"	"156.3"	"105.3"	"100.0"	"72.1"	"107.7"	"123.5"	"134.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86WR7"	"Proline and serine-rich protein 2 OS=Homo sapiens OX=9606 GN=PROSER2 PE=1 SV=2"	"7"	"2"	"4"	"2"	"435"	"45.8"	"7.20"	"830.12"	"7.07"	"2"	"2"	""	""	""	"Pf15385"	"254427"	"ENSG00000148426"	"PROSER2"	"D3DRR8; hsa:254427; Q5W0J9; Q5W0K0; Q5W0K1; Q5W0K2; Q6PJC8; Q86WR7; Q8N317"	""	""	"0"	"0"	"17.4"	"23.9"	"39.4"	"21.2"	"29.8"	"18.5"	"68.6"	"49.0"	"61.5"	"59.2"	"88.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14320"	"Protein FAM50A OS=Homo sapiens OX=9606 GN=FAM50A PE=1 SV=2"	"6"	"2"	"5"	"2"	"339"	"40.2"	"6.83"	"902.32"	"7.05"	"2"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	"Pf04921"	"9130"	"ENSG00000071859"	"FAM50A"	"A8KAQ4; B2R997; hsa:9130; Q14320; Q5HY37; Q6PJH5"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"126.4"	"296.4"	"265.4"	"114.5"	"294.3"	"131.9"	"230.3"	"174.4"	"282.6"	"381.2"	"635.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H993"	"Damage-control phosphatase ARMT1 OS=Homo sapiens OX=9606 GN=ARMT1 PE=1 SV=1"	"6"	"2"	"3"	"2"	"441"	"51.1"	"5.76"	"323.64"	"7.03"	"1"	"2"	"other metabolic processes;stress response"	""	"other molecular function"	"Pf01937"	"79624"	"ENSG00000146476"	"ARMT1"	"hsa:79624; Q96FC6; Q9H993; Q9UFY5"	""	""	"0"	"0"	"28.2"	"79.1"	"80.9"	"38.0"	"71.8"	"37.6"	"52.8"	"69.9"	"153.8"	"252.7"	"417.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P158"	"Putative ATP-dependent RNA helicase DHX57 OS=Homo sapiens OX=9606 GN=DHX57 PE=1 SV=2"	"2"	"2"	"4"	"1"	"1386"	"155.5"	"7.71"	"704.76"	"7.02"	"2"	"2"	""	""	"other molecular function"	"Pf00270, Pf00271, Pf04408, Pf05773, Pf07717, Pf18044"	"90957"	"ENSG00000163214"	"DHX57"	"A2RRC7; hsa:90957; Q53SI4; Q6P158; Q6P9G1; Q7Z6H3; Q8NG17; Q96M33"	""	""	"0"	"0"	"28.3"	"42.4"	"43.4"	"21.2"	"54.0"	"30.2"	"41.9"	"42.4"	"65.5"	"67.4"	"93.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P43250"	"G protein-coupled receptor kinase 6 OS=Homo sapiens OX=9606 GN=GRK6 PE=1 SV=2"	"5"	"2"	"4"	"2"	"576"	"65.9"	"8.00"	"749.73"	"7.01"	"2"	"2"	"cell-cell signaling;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00615"	"2870"	"ENSG00000198055"	"GRK6"	"hsa:2870; O60541; P43250; Q13652"	"Follicle stimulating hormone (FSH) signaling pathway; Corticotropin-releasing hormone signaling pathway; Myometrial relaxation and contraction pathways; Chemokine signaling pathway; Calcium regulation in cardiac cells"	"G alpha (s) signalling events"	"6"	"0"	"25.3"	"40.8"	"52.9"	"20.6"	"40.9"	"24.9"	"67.4"	"80.0"	"187.5"	"346.3"	"529.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13084"	"39S ribosomal protein L28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL28 PE=1 SV=4"	"16"	"3"	"4"	"3"	"256"	"30.1"	"8.29"	"654.91"	"7.00"	"2"	"2"	"protein metabolism;other metabolic processes"	"other membranes;cytosol;mitochondrion;translational apparatus"	"other molecular function"	"Pf00830"	"10573"	"ENSG00000086504"	"MRPL28"	"B2RCM4; D3DU46; hsa:10573; Q13084; Q4TT39; Q96S26; Q9BQD8; Q9BR04"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"117.2"	"385.1"	"331.0"	"102.8"	"284.9"	"132.6"	"181.3"	"167.4"	"243.8"	"297.8"	"540.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46976"	"Glycogenin-1 OS=Homo sapiens OX=9606 GN=GYG1 PE=1 SV=4"	"6"	"2"	"4"	"2"	"350"	"39.4"	"5.53"	"870.31"	"6.99"	"2"	"2"	"other metabolic processes"	"non-structural extracellular;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01501"	"2992"	"ENSG00000163754"	"GYG1"	"D3DNH0; D3DNH1; D3DNH2; hsa:2992; P46976; Q6FHZ1; Q9UNV0"	"Insulin signaling; Glycogen synthesis and degradation; Disorders of galactose metabolism"	"Neutrophil degranulation; Glycogen synthesis; Glycogen breakdown (glycogenolysis); Myoclonic epilepsy of Lafora; Glycogen storage disease type II (GAA); Glycogen storage disease type XV (GYG1); Glycogen storage disease type 0 (muscle GYS1)"	"10"	"0"	"104.8"	"210.0"	"232.3"	"130.0"	"222.4"	"125.1"	"165.0"	"148.4"	"178.3"	"220.7"	"330.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12931"	"Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3"	"4"	"2"	"4"	"1"	"704"	"80.1"	"8.21"	"823.27"	"6.99"	"2"	"2"	"other biological processes"	"other membranes;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00183, Pf02518"	"10131"	"ENSG00000126602"	"TRAP1"	"B4DR68; D3DUC8; F5H897; hsa:10131; O43642; O75235; Q12931; Q9UHL5"	"TNF-alpha signaling pathway; Clock-controlled autophagy in bone metabolism"	"Respiratory electron transport"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2G9"	"Protein strawberry notch homolog 2 OS=Homo sapiens OX=9606 GN=SBNO2 PE=2 SV=3"	"2"	"3"	"4"	"3"	"1366"	"150.2"	"6.52"	"237.00"	"6.99"	"1"	"3"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf13871, Pf13872"	"22904"	"ENSG00000064932; ENSG00000278788"	"SBNO2"	"A8K8P2; B3KWJ1; hsa:22904; O75257; Q3KQX0; Q8TEM0; Q9Y2G9"	""	""	"0"	"0"	"142.6"	"583.6"	"452.3"	"93.1"	"432.8"	"137.2"	"215.7"	"199.2"	"387.8"	"495.3"	"732.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NT62"	"Ubiquitin-like-conjugating enzyme ATG3 OS=Homo sapiens OX=9606 GN=ATG3 PE=1 SV=1"	"4"	"1"	"4"	"1"	"314"	"35.8"	"4.74"	"673.82"	"6.99"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf03987"	"64422"	"ENSG00000144848"	"ATG3"	"hsa:64422; Q6PKC5; Q9H6L9; Q9NT62"	"Nanoparticle triggered autophagic cell death; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Autophagy; Clock-controlled autophagy in bone metabolism"	"Macroautophagy"	"5"	"0"	"43.9"	"144.7"	"137.6"	"39.3"	"117.3"	"67.6"	"62.2"	"49.5"	"67.8"	"99.0"	"136.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NZJ9"	"Diphosphoinositol polyphosphate phosphohydrolase 2 OS=Homo sapiens OX=9606 GN=NUDT4 PE=1 SV=2"	"11"	"2"	"4"	"2"	"180"	"20.3"	"6.35"	"823.94"	"6.97"	"2"	"2"	"other metabolic processes;signal transduction"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00293"	"11163"	"ENSG00000173598"	"NUDT4"	"B7Z916; hsa:11163; Q4AEJ6; Q53EZ2; Q68DD7; Q9NPC5; Q9NS30; Q9NZJ9; Q9NZK0; Q9NZK1"	""	"Synthesis of pyrophosphates in the cytosol"	"1"	"0"	"26.4"	"100.8"	"88.3"	"24.5"	"92.6"	"51.3"	"115.0"	"139.3"	"310.4"	"516.5"	"799.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P45880"	"Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2"	"9"	"3"	"6"	"3"	"294"	"31.5"	"7.56"	"858.21"	"6.95"	"3"	"3"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"other membranes;cytoskeleton;mitochondrion;other cell component"	"transporter activity;other molecular function"	"Pf01459"	"7417"	"ENSG00000165637"	"VDAC2"	"hsa:7417; P45880; Q5VWK1; Q5VWK3; Q6IB40; Q7L3J5; Q9BWK8; Q9Y5I6"	"Alzheimer's disease and miRNA effects; Ferroptosis; Alzheimer's disease"	"Ub-specific processing proteases; Mitochondrial calcium ion transport"	"5"	"0"	"62.8"	"292.1"	"232.5"	"44.9"	"187.5"	"75.6"	"100.4"	"78.6"	"97.6"	"154.0"	"276.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2W2"	"WW domain-binding protein 11 OS=Homo sapiens OX=9606 GN=WBP11 PE=1 SV=1"	"4"	"2"	"4"	"2"	"641"	"70.0"	"8.38"	"729.72"	"6.94"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09429"	"51729"	"ENSG00000084463"	"WBP11"	"hsa:51729; Q96AY8; Q9Y2W2"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"57.7"	"101.3"	"111.8"	"54.0"	"118.7"	"71.4"	"111.3"	"93.3"	"117.8"	"182.5"	"183.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96RF0"	"Sorting nexin-18 OS=Homo sapiens OX=9606 GN=SNX18 PE=1 SV=2"	"5"	"4"	"6"	"4"	"628"	"68.9"	"5.68"	"1213.09"	"6.89"	"4"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00787, Pf10456, Pf14604"	"112574"	"ENSG00000178996"	"SNX18"	"B4E2B3; H7BXX3; hsa:112574; Q05BB3; Q0VG02; Q96RF0"	""	"Clathrin-mediated endocytosis"	"1"	"0"	"77.6"	"145.7"	"168.0"	"68.5"	"167.3"	"94.1"	"323.4"	"496.6"	"1365.9"	"2208.7"	"3221.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P15121"	"Aldo-keto reductase family 1 member B1 OS=Homo sapiens OX=9606 GN=AKR1B1 PE=1 SV=3"	"8"	"3"	"5"	"2"	"316"	"35.8"	"6.98"	"569.44"	"6.85"	"2"	"3"	"other metabolic processes;stress response;developmental processes;other biological processes"	"non-structural extracellular;cytosol;nucleus"	"other molecular function"	"Pf00248"	"231"	"ENSG00000085662"	"AKR1B1"	"B2R8N3; hsa:231; P15121; Q5U031; Q6FGA4; Q6ICP2; Q9BS21; Q9UCI9"	"Eicosanoid metabolism via cyclooxygenases (COX); Disorders of galactose metabolism ; Polyol pathway; Metapathway biotransformation Phase I and II"	"Pregnenolone biosynthesis; Fructose biosynthesis"	"6"	"1"	"161.4"	"1107.4"	"946.0"	"76.0"	"830.3"	"221.1"	"305.1"	"218.3"	"304.4"	"364.0"	"952.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49721"	"Proteasome subunit beta type-2 OS=Homo sapiens OX=9606 GN=PSMB2 PE=1 SV=1"	"9"	"2"	"4"	"2"	"201"	"22.8"	"7.02"	"571.15"	"6.84"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf00227"	"5690"	"ENSG00000126067"	"PSMB2"	"D3DPS0; hsa:5690; P31145; P49721; Q9BWZ9"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Separation of Sister Chromatids; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"62"	"0"	"87.2"	"161.8"	"186.3"	"74.9"	"198.9"	"110.0"	"219.5"	"181.3"	"234.3"	"355.7"	"516.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52298"	"Nuclear cap-binding protein subunit 2 OS=Homo sapiens OX=9606 GN=NCBP2 PE=1 SV=1"	"19"	"2"	"3"	"2"	"156"	"18.0"	"8.21"	"298.84"	"6.83"	"1"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"22916"	"ENSG00000114503"	"NCBP2"	"B2RE91; B4DMK7; E9PAR5; hsa:22916; P52298; Q14924; Q2TS50"	"mRNA processing; 3q29 copy number variation syndrome"	"mRNA Splicing - Major Pathway; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; snRNP Assembly; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Abortive elongation of HIV-1 transcript in the absence of Tat; RNA Polymerase II Pre-transcription Events; RNA polymerase II transcribes snRNA genes; mRNA Capping; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Signaling by FGFR2 IIIa TM; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"29"	"0"	"36.1"	"64.9"	"72.6"	"30.2"	"81.7"	"31.6"	"68.6"	"63.9"	"64.8"	"79.2"	"106.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O76021"	"Ribosomal L1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RSL1D1 PE=1 SV=3"	"8"	"2"	"4"	"2"	"490"	"54.9"	"10.13"	"800.62"	"6.82"	"2"	"2"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00687"	"26156"	"ENSG00000171490"	"RSL1D1"	"B4DJ58; D3DUG7; hsa:26156; O76021; Q2M1T7; Q6PL22; Q8IWS7; Q8WUZ1; Q9HDA9; Q9Y3Z9"	""	""	"0"	"0"	"11.4"	"29.5"	"37.5"	"12.1"	"26.7"	"16.9"	"36.8"	"31.2"	"46.0"	"63.2"	"72.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P53597"	"Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLG1 PE=1 SV=4"	"9"	"2"	"3"	"2"	"346"	"36.2"	"8.79"	"396.89"	"6.81"	"1"	"2"	"other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf00549, Pf02629"	"8802"	"ENSG00000163541"	"SUCLG1"	"hsa:8802; P53597; Q9BWB0; Q9UNP6"	"Amino acid metabolism; TCA cycle (aka Krebs or citric acid cycle)"	"Citric acid cycle (TCA cycle)"	"3"	"0"	"43.3"	"127.0"	"121.5"	"36.7"	"105.7"	"52.8"	"86.2"	"75.0"	"108.5"	"134.2"	"216.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P80303"	"Nucleobindin-2 OS=Homo sapiens OX=9606 GN=NUCB2 PE=1 SV=3"	"7"	"2"	"4"	"2"	"420"	"50.2"	"5.12"	"702.18"	"6.80"	"2"	"2"	"signal transduction"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf13499"	"4925"	"ENSG00000070081"	"NUCB2"	"A8K642; D3DQX5; hsa:4925; P80303; Q8NFT5; V9HW75"	""	""	"0"	"0"	"29.5"	"78.2"	"94.1"	"30.0"	"83.4"	"37.4"	"55.2"	"40.2"	"62.3"	"79.3"	"120.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23526"	"Adenosylhomocysteinase OS=Homo sapiens OX=9606 GN=AHCY PE=1 SV=4"	"8"	"3"	"5"	"3"	"432"	"47.7"	"6.34"	"733.35"	"6.79"	"2"	"3"	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00670, Pf05221"	"191"	"ENSG00000101444"	"AHCY"	"A8K307; B3KUN3; E1P5P2; F5H737; hsa:191; P23526; Q96A36"	"Folate metabolism; Trans-sulfuration pathway; One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways; Methionine de novo and salvage pathway; Ethanol effects on histone modifications"	"Methylation; Sulfur amino acid metabolism; Metabolism of ingested SeMet, Sec, MeSec into H2Se; Defective AHCY causes HMAHCHD"	"10"	"0"	"90.3"	"581.1"	"430.5"	"32.7"	"406.1"	"106.4"	"181.1"	"150.0"	"198.3"	"281.8"	"534.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96Q05"	"Trafficking protein particle complex subunit 9 OS=Homo sapiens OX=9606 GN=TRAPPC9 PE=1 SV=2"	"2"	"2"	"4"	"2"	"1148"	"128.4"	"6.62"	"748.61"	"6.79"	"2"	"2"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf08626"	"83696"	"ENSG00000167632"	"TRAPPC9"	"hsa:83696; Q4VTT3; Q658K7; Q6P149; Q6ZQT3; Q7L5C4; Q86Y21; Q96Q05; Q96SL2; Q9BQA2"	""	"COPII-mediated vesicle transport; RAB GEFs exchange GTP for GDP on RABs"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60763"	"General vesicular transport factor p115 OS=Homo sapiens OX=9606 GN=USO1 PE=1 SV=2"	"3"	"2"	"4"	"2"	"962"	"107.8"	"4.91"	"627.49"	"6.76"	"2"	"2"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	""	"Pf04869, Pf04871, Pf18770"	"8615"	"ENSG00000138768"	"USO1"	"B2RAQ0; hsa:8615; O60763; Q6PK63; Q86TB8; Q8N592"	""	"COPI-mediated anterograde transport; COPII-mediated vesicle transport; Golgi Cisternae Pericentriolar Stack Reorganization"	"3"	"0"	"37.7"	"35.9"	"47.8"	"32.7"	"67.3"	"43.6"	"72.1"	"38.4"	"63.0"	"57.9"	"83.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96NC0"	"Zinc finger matrin-type protein 2 OS=Homo sapiens OX=9606 GN=ZMAT2 PE=1 SV=1"	"19"	"5"	"8"	"5"	"199"	"23.6"	"9.01"	"1277.58"	"6.74"	"5"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf12171"	"153527"	"ENSG00000146007"	"ZMAT2"	"hsa:153527; Q96NC0"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"386.3"	"616.0"	"672.1"	"324.0"	"651.2"	"366.8"	"867.3"	"603.4"	"950.1"	"1258.1"	"1914.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P84103"	"Serine/arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1"	"28"	"4"	"5"	"4"	"164"	"19.3"	"11.65"	"567.72"	"6.73"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6428"	"ENSG00000112081"	"SRSF3"	"B4E241; hsa:6428; O08831; P23152; P84103; Q5R3K0"	"mRNA processing"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"6"	"0"	"227.4"	"671.4"	"653.2"	"171.1"	"607.6"	"226.8"	"735.8"	"545.2"	"624.2"	"906.1"	"1392.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EI5"	"Transcription elongation factor A protein-like 4 OS=Homo sapiens OX=9606 GN=TCEAL4 PE=1 SV=2"	"9"	"2"	"4"	"2"	"215"	"24.6"	"5.20"	"735.92"	"6.73"	"2"	"2"	""	"nucleus"	""	"Pf04538"	"79921"	"ENSG00000133142"	"TCEAL4"	"hsa:79921; Q8WY12; Q96EI5; Q9H2H1; Q9H775"	""	""	"0"	"0"	"95.0"	"59.2"	"79.1"	"71.0"	"128.8"	"115.2"	"102.3"	"64.6"	"105.3"	"92.4"	"106.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NW08"	"DNA-directed RNA polymerase III subunit RPC2 OS=Homo sapiens OX=9606 GN=POLR3B PE=1 SV=2"	"2"	"2"	"3"	"2"	"1133"	"127.7"	"8.50"	""	"6.73"	""	"2"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00562, Pf04560, Pf04561, Pf04563, Pf04565, Pf04566, Pf04567"	"55703"	"ENSG00000013503"	"POLR3B"	"A8K6H0; B3KV73; F5H1E6; hsa:55703; Q9NW08; Q9NW59"	"Pyrimidine metabolism; Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation"	"10"	"0"	"118.5"	"292.1"	"1866.6"	"140.0"	"162.5"	"142.1"	"241.7"	"247.6"	"474.0"	"494.6"	"261.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UJZ1"	"Stomatin-like protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=STOML2 PE=1 SV=1"	"7"	"2"	"4"	"2"	"356"	"38.5"	"7.39"	"717.36"	"6.71"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;mitochondrion"	"signal transduction activity or receptor binding;other molecular function"	"Pf01145, Pf16200"	"30968"	"ENSG00000165283"	"STOML2"	"B4E1K7; D3DRN3; hsa:30968; O60376; Q53G29; Q96FY2; Q9P042; Q9UJZ1"	""	"Processing of SMDT1"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBL3"	"Set1/Ash2 histone methyltransferase complex subunit ASH2 OS=Homo sapiens OX=9606 GN=ASH2L PE=1 SV=1"	"5"	"2"	"4"	"2"	"628"	"68.7"	"5.69"	"759.33"	"6.70"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00622"	"9070"	"ENSG00000129691"	"ASH2L"	"A8K7C3; D3DSW9; hsa:9070; O60659; O60660; Q96B62; Q9UBL3"	"Kleefstra syndrome"	"Deactivation of the beta-catenin transactivating complex; Formation of the beta-catenin:TCF transactivating complex; Activation of anterior HOX genes in hindbrain development during early embryogenesis; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Formation of WDR5-containing histone-modifying complexes; PKMTs methylate histone lysines"	"7"	"0"	"21.0"	"37.9"	"39.4"	"20.3"	"41.2"	"22.9"	"42.5"	"33.2"	"48.6"	"53.1"	"77.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H9A6"	"Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1"	"4"	"3"	"5"	"3"	"602"	"68.2"	"6.43"	"536.25"	"6.66"	"2"	"3"	""	""	""	"Pf00560, Pf13855"	"55631"	"ENSG00000066557"	"LRRC40"	"hsa:55631; Q9BTR7; Q9H9A6; Q9NSK1; Q9NXC1"	""	""	"0"	"0"	"31.6"	"281.6"	"175.4"	"11.8"	"138.0"	"35.9"	"65.7"	"57.2"	"71.3"	"110.2"	"224.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UHB6"	"LIM domain and actin-binding protein 1 OS=Homo sapiens OX=9606 GN=LIMA1 PE=1 SV=1"	"3"	"2"	"3"	"2"	"759"	"85.2"	"6.84"	"407.96"	"6.66"	"1"	"2"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412"	"51474"	"ENSG00000050405"	"LIMA1"	"B2RB09; hsa:51474; Q2TAN7; Q59FE8; Q9BVF2; Q9H8J1; Q9HBN5; Q9NX96; Q9NXC3; Q9NXU6; Q9P0H8; Q9UHB5; Q9UHB6"	""	""	"0"	"0"	"86.6"	"111.6"	"131.3"	"71.8"	"115.7"	"84.8"	"100.6"	"63.4"	"89.1"	"86.5"	"103.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35610"	"Sterol O-acyltransferase 1 OS=Homo sapiens OX=9606 GN=SOAT1 PE=1 SV=3"	"3"	"1"	"4"	"1"	"550"	"64.7"	"8.94"	"721.61"	"6.65"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf03062"	"6646"	"ENSG00000057252"	"SOAT1"	"A6NC40; A8K3P4; A9Z1V7; B4DU95; hsa:6646; P35610; Q5T0X4; Q8N1E4"	"Statin inhibition of cholesterol production; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Cholesterol metabolism"	"LDL clearance"	"4"	"0"	"21.1"	"44.3"	"54.4"	"23.4"	"46.2"	"26.6"	"40.0"	"28.5"	"36.4"	"50.1"	"65.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A5YKK6"	"CCR4-NOT transcription complex subunit 1 OS=Homo sapiens OX=9606 GN=CNOT1 PE=1 SV=2"	"1"	"2"	"4"	"2"	"2376"	"266.8"	"7.11"	"553.61"	"6.64"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf04054, Pf12842, Pf16415, Pf16417, Pf16418"	"23019"	"ENSG00000125107"	"CNOT1"	"A5YKK6; hsa:23019; Q68DX7; Q7Z3K2; Q8IWB8; Q8TB53; Q9BVZ6; Q9UFR8; Q9UI27; Q9Y2L0"	"Ciliary landscape"	"Deadenylation of mRNA; TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"	"3"	"0"	"69.9"	"185.1"	"195.1"	"74.5"	"171.5"	"85.9"	"135.9"	"121.0"	"173.1"	"248.6"	"365.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49773"	"Histidine triad nucleotide-binding protein 1 OS=Homo sapiens OX=9606 GN=HINT1 PE=1 SV=2"	"11"	"1"	"4"	"1"	"126"	"13.8"	"6.95"	"806.02"	"6.62"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf01230"	"3094"	"ENSG00000169567"	"HINT1"	"hsa:3094; P49773; Q9H5W8"	""	""	"0"	"0"	"52.4"	"300.5"	"222.3"	"36.9"	"192.3"	"75.8"	"106.9"	"81.7"	"115.4"	"129.4"	"258.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99700"	"Ataxin-2 OS=Homo sapiens OX=9606 GN=ATXN2 PE=1 SV=2"	"2"	"2"	"4"	"1"	"1313"	"140.2"	"9.57"	"663.04"	"6.60"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity"	"Pf06741, Pf07145, Pf14438"	"6311"	"ENSG00000204842"	"ATXN2"	"A6NLD4; hsa:6311; Q24JQ7; Q6ZQZ7; Q99493; Q99700"	"Parkinson's disease pathway; EGF/EGFR signaling pathway"	""	"2"	"0"	"28.1"	"72.7"	"74.2"	"30.8"	"74.2"	"30.0"	"67.7"	"55.6"	"84.8"	"116.0"	"153.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y678"	"Coatomer subunit gamma-1 OS=Homo sapiens OX=9606 GN=COPG1 PE=1 SV=1"	"2"	"2"	"6"	"1"	"874"	"97.7"	"5.47"	"842.21"	"6.60"	"2"	"2"	"transport;other biological processes"	"other membranes;cytosol;ER/Golgi"	"other molecular function"	"Pf01602, Pf08752, Pf16381"	"22820"	"ENSG00000181789"	"COPG1"	"A8K6M8; B3KMF6; hsa:22820; Q54AC4; Q9Y678"	"VEGFA-VEGFR2 signaling"	"COPI-mediated anterograde transport; COPI-dependent Golgi-to-ER retrograde traffic"	"3"	"1"	"129.8"	"405.5"	"332.0"	"84.5"	"308.9"	"136.0"	"188.7"	"149.9"	"225.5"	"293.5"	"490.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30566"	"Adenylosuccinate lyase OS=Homo sapiens OX=9606 GN=ADSL PE=1 SV=2"	"5"	"2"	"4"	"2"	"484"	"54.9"	"7.11"	"677.01"	"6.58"	"2"	"2"	"other metabolic processes;stress response;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00206, Pf10397"	"158"	"ENSG00000239900"	"ADSL"	"B0QY76; hsa:158; O75495; P30566; Q5TI34"	""	"Purine ribonucleoside monophosphate biosynthesis"	"1"	"0"	"109.0"	"255.7"	"236.5"	"95.4"	"249.3"	"107.9"	"170.7"	"158.2"	"211.1"	"289.9"	"393.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13807"	"Glycogen [starch] synthase, muscle OS=Homo sapiens OX=9606 GN=GYS1 PE=1 SV=2"	"3"	"2"	"4"	"2"	"737"	"83.7"	"6.18"	"705.10"	"6.57"	"2"	"2"	"other metabolic processes;developmental processes"	"cytosol;other cell component"	"other molecular function"	"Pf05693"	"2997"	"ENSG00000104812"	"GYS1"	"hsa:2997; P13807; Q9BTT9"	"AMP-activated protein kinase signaling; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Insulin signaling; Glycogen synthesis and degradation; Disorders of galactose metabolism ; 2q37 copy number variation syndrome"	"Glycogen synthesis; Myoclonic epilepsy of Lafora; Glycogen storage disease type XV (GYG1); Glycogen storage disease type 0 (muscle GYS1)"	"12"	"0"	"79.4"	"155.7"	"183.8"	"90.2"	"194.3"	"98.5"	"138.1"	"110.7"	"145.4"	"177.0"	"244.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BYD1"	"39S ribosomal protein L13, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL13 PE=1 SV=1"	"17"	"2"	"4"	"2"	"178"	"20.7"	"9.16"	"723.00"	"6.55"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00572"	"28998"	"ENSG00000172172"	"MRPL13"	"B2R4R8; hsa:28998; Q9BYD1; Q9UI04"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"19.3"	"40.1"	"34.5"	"23.0"	"43.1"	"20.5"	"32.8"	"31.7"	"36.8"	"60.5"	"93.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61962"	"DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1"	"6"	"2"	"5"	"2"	"342"	"38.9"	"5.52"	"971.84"	"6.54"	"2"	"2"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00400"	"10238"	"ENSG00000136485"	"DCAF7"	"B4E039; D3DU14; hsa:10238; O15491; P61962; Q9DAE4"	"Ciliary landscape; DYRK1A involvement regarding cell proliferation in brain development"	"Neddylation; Association of TriC/CCT with target proteins during biosynthesis"	"4"	"0"	"136.5"	"263.7"	"264.5"	"124.1"	"283.9"	"170.1"	"276.5"	"218.5"	"301.6"	"378.9"	"441.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13620"	"Cullin-4B OS=Homo sapiens OX=9606 GN=CUL4B PE=1 SV=4"	"1"	"1"	"4"	"1"	"913"	"103.9"	"7.37"	"629.34"	"6.54"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00888, Pf10557"	"8450"	"ENSG00000158290"	"CUL4B"	"B1APK5; B3KVX4; B7Z5K8; hsa:8450; Q13620; Q6PIE4; Q6UP07; Q7Z673; Q9BY37; Q9UEB7; Q9UED7"	"Mesodermal commitment pathway; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"Formation of Incision Complex in GG-NER; DNA Damage Recognition in GG-NER; Neddylation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Recognition of DNA damage by PCNA-containing replication complex; Dual Incision in GG-NER"	"13"	"0"	"10.3"	"58.3"	"43.6"	"8.4"	"36.3"	"18.0"	"18.8"	"19.2"	"34.4"	"39.1"	"72.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30520"	"Adenylosuccinate synthetase isozyme 2 OS=Homo sapiens OX=9606 GN=ADSS2 PE=1 SV=3"	"5"	"2"	"4"	"2"	"456"	"50.1"	"6.55"	"607.43"	"6.52"	"2"	"2"	"other metabolic processes;other biological processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00709"	"159"	"ENSG00000035687"	"ADSS2"	"B1AQM5; hsa:159; P30520; Q96EG7"	""	"Purine ribonucleoside monophosphate biosynthesis"	"1"	"0"	"40.9"	"152.8"	"146.6"	"29.0"	"149.3"	"59.1"	"96.6"	"87.8"	"92.2"	"133.2"	"208.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UPT5"	"Exocyst complex component 7 OS=Homo sapiens OX=9606 GN=EXOC7 PE=1 SV=3"	"4"	"2"	"4"	"2"	"735"	"83.3"	"6.79"	"683.83"	"6.52"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf03081"	"23265"	"ENSG00000182473"	"EXOC7"	"B5MC69; B8XXP2; hsa:23265; Q8ND93; Q8WV91; Q96FF0; Q9H8C3; Q9H9X3; Q9HA32; Q9UPT5"	"Angiopoietin-like protein 8 regulatory pathway; Ciliary landscape"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"5"	"0"	"7.2"	"14.1"	"20.2"	"5.4"	"8.6"	"8.4"	"16.1"	"12.3"	"23.5"	"50.1"	"88.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92747"	"Actin-related protein 2/3 complex subunit 1A OS=Homo sapiens OX=9606 GN=ARPC1A PE=2 SV=2"	"7"	"3"	"4"	"3"	"370"	"41.5"	"8.18"	"627.84"	"6.50"	"2"	"2"	"cell organization and biogenesis"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf00400"	"10552"	"ENSG00000241685"	"ARPC1A"	"A4D276; B4DLQ7; D6W5S1; hsa:10552; Q7Z5U8; Q86WU5; Q8IXQ0; Q92747"	"Pathogenic Escherichia coli infection"	"Clathrin-mediated endocytosis; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; EPHB-mediated forward signaling"	"6"	"0"	"115.6"	"199.6"	"239.2"	"114.9"	"221.7"	"127.9"	"308.2"	"348.4"	"494.3"	"968.2"	"2267.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16543"	"Hsp90 co-chaperone Cdc37 OS=Homo sapiens OX=9606 GN=CDC37 PE=1 SV=1"	"11"	"3"	"6"	"3"	"378"	"44.4"	"5.25"	"932.52"	"6.47"	"3"	"3"	"stress response;transport;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity;other molecular function"	"Pf03234, Pf08564, Pf08565"	"11140"	"ENSG00000105401"	"CDC37"	"hsa:11140; Q16543; Q53YA2"	"TNF-alpha signaling pathway; Aryl hydrocarbon receptor pathway; Aryl hydrocarbon receptor pathway; Nuclear receptors meta-pathway; Interactions between LOXL4 and oxidative stress pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway"	"RHOBTB2 GTPase cycle; Signaling by ERBB2 KD Mutants; Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; Constitutive Signaling by EGFRvIII; Signaling by ERBB2 ECD mutants; Regulation of necroptotic cell death; Downregulation of ERBB2 signaling; Signaling by ERBB2 TMD/JMD mutants; Constitutive Signaling by Overexpressed ERBB2; Drug-mediated inhibition of ERBB2 signaling; Resistance of ERBB2 KD mutants to trastuzumab; Resistance of ERBB2 KD mutants to sapitinib; Resistance of ERBB2 KD mutants to tesevatinib; Resistance of ERBB2 KD mutants to neratinib; Resistance of ERBB2 KD mutants to osimertinib; Resistance of ERBB2 KD mutants to afatinib; Resistance of ERBB2 KD mutants to AEE788; Resistance of ERBB2 KD mutants to lapatinib; Drug resistance in ERBB2 TMD/JMD mutants"	"27"	"0"	"71.6"	"243.1"	"236.4"	"61.6"	"217.9"	"88.4"	"115.3"	"87.2"	"136.0"	"166.6"	"277.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75792"	"Ribonuclease H2 subunit A OS=Homo sapiens OX=9606 GN=RNASEH2A PE=1 SV=2"	"10"	"2"	"4"	"2"	"299"	"33.4"	"5.25"	"749.04"	"6.47"	"2"	"2"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01351"	"10535"	"ENSG00000104889"	"RNASEH2A"	"B2RCY1; hsa:10535; O75792; Q96F11"	""	""	"0"	"0"	"13.5"	"54.1"	"59.5"	"14.6"	"41.3"	"25.0"	"33.1"	"33.4"	"52.3"	"62.2"	"71.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H9J2"	"39S ribosomal protein L44, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL44 PE=1 SV=1"	"8"	"3"	"5"	"3"	"332"	"37.5"	"8.40"	"1055.21"	"6.47"	"3"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"plasma membrane;other membranes;mitochondrion;translational apparatus;nucleus"	"nucleic acid binding activity;other molecular function"	""	"65080"	"ENSG00000135900"	"MRPL44"	"hsa:65080; Q53S16; Q6IA62; Q9H821; Q9H9J2"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"176.0"	"473.3"	"467.6"	"146.7"	"388.8"	"223.5"	"301.4"	"226.2"	"317.4"	"423.8"	"695.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60610"	"Protein diaphanous homolog 1 OS=Homo sapiens OX=9606 GN=DIAPH1 PE=1 SV=2"	"2"	"2"	"4"	"2"	"1272"	"141.3"	"5.41"	"641.52"	"6.44"	"2"	"2"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf02181, Pf06346, Pf06367, Pf06371"	"1729"	"ENSG00000131504"	"DIAPH1"	"A6NF18; B7ZKW2; E9PEZ2; hsa:1729; O60610; Q17RN4; Q59FH8; Q9UC76"	"Microtubule cytoskeleton regulation; AGE/RAGE pathway; Focal adhesion; Type 2 papillary renal cell carcinoma; Regulation of actin cytoskeleton; G13 signaling pathway"	"RHOC GTPase cycle; RHOA GTPase cycle; RHO GTPases Activate Formins; RHOB GTPase cycle; RHOD GTPase cycle; RHOF GTPase cycle; Neutrophil degranulation; ERBB2 Regulates Cell Motility"	"14"	"0"	"44.5"	"107.1"	"107.8"	"34.1"	"93.4"	"40.0"	"105.9"	"104.0"	"127.6"	"202.2"	"252.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14927"	"Cytochrome b-c1 complex subunit 7 OS=Homo sapiens OX=9606 GN=UQCRB PE=1 SV=2"	"18"	"2"	"4"	"2"	"111"	"13.5"	"8.78"	"705.49"	"6.42"	"2"	"2"	"other metabolic processes;transport"	"other membranes;mitochondrion"	""	"Pf02271"	"7381"	"ENSG00000156467"	"UQCRB"	"E5RJU0; hsa:7381; P14927; Q6FGD1"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex III assembly; 11p11.2 copy number variation syndrome"	"Respiratory electron transport"	"5"	"0"	"67.6"	"354.6"	"298.9"	"52.9"	"266.3"	"69.4"	"514.6"	"467.5"	"639.8"	"1034.8"	"1574.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NXW9"	"Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 OS=Homo sapiens OX=9606 GN=ALKBH4 PE=1 SV=1"	"8"	"2"	"4"	"2"	"302"	"33.8"	"6.67"	"745.60"	"6.42"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"cytoskeletal activity;other molecular function"	""	"54784"	"ENSG00000160993"	"ALKBH4"	"hsa:54784; Q53H92; Q9H6A4; Q9NXW9"	""	""	"0"	"0"	"14.7"	"35.4"	"30.1"	"10.9"	"35.6"	"18.6"	"23.8"	"34.6"	"56.2"	"113.7"	"190.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P28072"	"Proteasome subunit beta type-6 OS=Homo sapiens OX=9606 GN=PSMB6 PE=1 SV=4"	"13"	"3"	"4"	"3"	"239"	"25.3"	"4.92"	"649.48"	"6.40"	"2"	"2"	"protein metabolism;other metabolic processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00227"	"5694"	"ENSG00000142507"	"PSMB6"	"hsa:5694; P28072; Q96J55"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A; MAPK6/MAPK4 signaling; The role of GTSE1 in G2/M progression after G2 checkpoint; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"62"	"0"	"202.9"	"349.3"	"365.6"	"157.9"	"328.9"	"184.0"	"599.7"	"478.9"	"638.3"	"860.9"	"1359.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HB21"	"Pleckstrin homology domain-containing family A member 1 OS=Homo sapiens OX=9606 GN=PLEKHA1 PE=1 SV=2"	"5"	"2"	"4"	"2"	"404"	"45.5"	"8.56"	"774.67"	"6.40"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00169"	"59338"	"ENSG00000107679"	"PLEKHA1"	"B3KQ55; D3DRE2; hsa:59338; Q9BVK0; Q9HB21"	""	"Synthesis of PIPs at the plasma membrane"	"1"	"0"	"9.4"	"25.3"	"25.3"	"12.0"	"19.7"	"10.2"	"34.5"	"55.2"	"172.2"	"336.2"	"544.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q4G0J3"	"La-related protein 7 OS=Homo sapiens OX=9606 GN=LARP7 PE=1 SV=1"	"3"	"2"	"3"	"2"	"582"	"66.9"	"9.55"	"521.74"	"6.40"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf05383, Pf08777"	"51574"	"ENSG00000174720"	"LARP7"	"B2ZHN6; hsa:51574; Q3B7A9; Q4G0J3; Q9P1S7; Q9Y3Z8"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"85.0"	"110.3"	"151.8"	"54.1"	"166.9"	"91.9"	"118.9"	"88.2"	"129.2"	"146.7"	"212.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14579"	"Coatomer subunit epsilon OS=Homo sapiens OX=9606 GN=COPE PE=1 SV=3"	"10"	"2"	"3"	"2"	"308"	"34.5"	"5.12"	"319.14"	"6.39"	"1"	"2"	"transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus"	"other molecular function"	"Pf04733"	"11316"	"ENSG00000105669"	"COPE"	"A6NE29; A6NKA3; hsa:11316; O14579; O76097; Q6IBB8; Q9UGP6"	""	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport"	"2"	"0"	"44.8"	"64.7"	"83.1"	"39.7"	"73.4"	"54.8"	"78.0"	"58.7"	"115.6"	"116.9"	"133.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P587"	"Acylpyruvase FAHD1, mitochondrial OS=Homo sapiens OX=9606 GN=FAHD1 PE=1 SV=2"	"10"	"2"	"4"	"2"	"224"	"24.8"	"7.39"	"786.69"	"6.38"	"2"	"2"	"other metabolic processes"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf01557"	"81889"	"ENSG00000180185"	"FAHD1"	"B1AK40; B1AK41; hsa:81889; Q6FIC7; Q6P587; Q96RY1; Q9H0N6"	""	"Citric acid cycle (TCA cycle)"	"1"	"0"	"80.0"	"132.6"	"148.6"	"67.1"	"148.1"	"87.9"	"194.8"	"186.5"	"252.4"	"350.9"	"602.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30040"	"Endoplasmic reticulum resident protein 29 OS=Homo sapiens OX=9606 GN=ERP29 PE=1 SV=4"	"8"	"2"	"4"	"2"	"261"	"29.0"	"7.31"	"757.64"	"6.38"	"2"	"2"	"transport;other biological processes"	"ER/Golgi;other cell component"	"other molecular function"	"Pf07749, Pf07912"	"10961"	"ENSG00000089248"	"ERP29"	"C9J183; hsa:10961; P30040; Q3MJC3; Q6FHT4"	""	""	"0"	"0"	"93.2"	"324.5"	"265.5"	"69.1"	"237.8"	"109.4"	"157.7"	"135.3"	"168.2"	"200.6"	"361.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TDN4"	"CDK5 and ABL1 enzyme substrate 1 OS=Homo sapiens OX=9606 GN=CABLES1 PE=1 SV=2"	"6"	"3"	"6"	"3"	"633"	"67.6"	"9.17"	"1006.92"	"6.38"	"3"	"3"	"cell cycle OR cell proliferation;developmental processes;other biological processes"	"cytosol;nucleus"	""	"Pf00134"	"91768"	"ENSG00000134508"	"CABLES1"	"B4DK60; hsa:91768; Q8N3Y8; Q8NA22; Q8TDN4; Q9BTG1"	""	"Factors involved in megakaryocyte development and platelet production; Cyclin E associated events during G1/S transition ; Cyclin A:Cdk2-associated events at S phase entry"	"3"	"0"	"46.3"	"96.9"	"110.5"	"47.1"	"113.0"	"59.7"	"148.4"	"192.3"	"398.5"	"596.0"	"862.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25325"	"3-mercaptopyruvate sulfurtransferase OS=Homo sapiens OX=9606 GN=MPST PE=1 SV=3"	"9"	"3"	"5"	"2"	"297"	"33.2"	"6.60"	"1028.32"	"6.38"	"3"	"2"	"other metabolic processes;developmental processes;other biological processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00581"	"4357"	"ENSG00000128309"	"MPST"	"A8MZ34; B3KP52; hsa:4357; J3KPV7; O75750; P25325; Q6FHN9"	"Trans-sulfuration pathway; Amino acid metabolism"	"Degradation of cysteine and homocysteine"	"3"	"0"	"41.2"	"267.1"	"233.5"	"24.9"	"179.0"	"66.7"	"95.7"	"73.0"	"104.7"	"118.9"	"238.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBU9"	"Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1"	"4"	"2"	"3"	"2"	"619"	"70.1"	"8.51"	"364.61"	"6.36"	"1"	"2"	"other metabolic processes;transport"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf02136, Pf03943, Pf09162"	"10482"	"ENSG00000162231"	"NXF1"	"B4E269; hsa:10482; Q99799; Q9UBU9; Q9UQL2"	"mRNA processing"	"Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript"	"5"	"0"	"7.3"	"29.4"	"22.7"	"9.4"	"19.4"	"11.8"	"28.5"	"14.3"	"25.2"	"34.0"	"49.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86YP4"	"Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1"	"3"	"2"	"4"	"2"	"633"	"68.0"	"9.94"	"799.34"	"6.36"	"2"	"2"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00320, Pf16563"	"54815"	"ENSG00000167491"	"GATAD2A"	"B5MC40; hsa:54815; Q7L3J2; Q86YP4; Q96F28; Q9NPU2; Q9NXS1"	""	"Potential therapeutics for SARS; Regulation of PTEN gene transcription; HDACs deacetylate histones; RNA Polymerase I Transcription Initiation; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of TP53 Activity through Acetylation"	"6"	"0"	"34.7"	"104.1"	"86.2"	"30.5"	"81.3"	"41.4"	"177.9"	"146.7"	"193.7"	"229.7"	"357.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BWT3"	"Poly(A) polymerase gamma OS=Homo sapiens OX=9606 GN=PAPOLG PE=1 SV=2"	"5"	"3"	"4"	"3"	"736"	"82.8"	"9.14"	"576.67"	"6.35"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01909, Pf04926, Pf04928"	"64895"	"ENSG00000115421"	"PAPOLG"	"B2RBH4; hsa:64895; Q59G05; Q969N1; Q9BWT3; Q9H8L2; Q9HAD0"	""	""	"0"	"0"	"47.7"	"74.9"	"88.1"	"45.4"	"118.0"	"59.3"	"122.6"	"121.6"	"213.5"	"352.8"	"502.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NC96"	"Adaptin ear-binding coat-associated protein 1 OS=Homo sapiens OX=9606 GN=NECAP1 PE=1 SV=2"	"9"	"2"	"4"	"2"	"275"	"29.7"	"6.80"	"771.82"	"6.34"	"2"	"2"	"transport"	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf07933"	"25977"	"ENSG00000089818"	"NECAP1"	"hsa:25977; Q2NL73; Q5XG95; Q6NWY6; Q8N153; Q8NC96; Q8NCB0; Q9BU52; Q9Y407"	""	"Golgi Associated Vesicle Biogenesis; Cargo recognition for clathrin-mediated endocytosis"	"3"	"0"	"69.2"	"109.2"	"96.7"	"51.0"	"128.3"	"81.6"	"128.5"	"171.5"	"354.7"	"543.4"	"791.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35244"	"Replication protein A 14 kDa subunit OS=Homo sapiens OX=9606 GN=RPA3 PE=1 SV=1"	"22"	"2"	"4"	"2"	"121"	"13.6"	"5.08"	"659.81"	"6.33"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf08661"	"6119"	"ENSG00000106399"	"RPA3"	"hsa:6119; P35244; Q549U6"	"Retinoblastoma gene in cancer; G1 to S cell cycle control; DNA replication; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"HSF1 activation; Fanconi Anemia Pathway; Regulation of HSF1-mediated heat shock response; Regulation of TP53 Activity through Phosphorylation; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Meiotic recombination; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Removal of the Flap Intermediate; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"36"	"0"	"33.2"	"63.9"	"74.9"	"33.3"	"76.0"	"43.6"	"53.0"	"39.7"	"62.6"	"69.3"	"96.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P42771"	"Cyclin-dependent kinase inhibitor 2A OS=Homo sapiens OX=9606 GN=CDKN2A PE=1 SV=2"	"19"	"2"	"4"	"2"	"156"	"16.5"	"5.81"	"641.45"	"6.33"	"2"	"2"	"cell cycle OR cell proliferation;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	""	"1029"	"ENSG00000147889"	"CDKN2A"	"A5X2G7; D3DRK1; G3XAG3; hsa:1029; O95440; P42771; Q15191; Q5VVJ5; Q96B52; Q9NP05"	"TP53 network; Cell cycle; Glioblastoma signaling pathways; Apoptosis; Bladder cancer; Vitamin D receptor pathway; Tumor suppressor activity of SMARCB1; Non-small cell lung cancer; Pancreatic adenocarcinoma pathway; G1 to S cell cycle control; Fragile X syndrome; Gastrin signaling pathway; Head and neck squamous cell carcinoma; Melanoma; Pleural mesothelioma; TROP2 regulatory signaling"	"Cyclin D associated events in G1; Oxidative Stress Induced Senescence; Oncogene Induced Senescence; Senescence-Associated Secretory Phenotype (SASP); Transcriptional Regulation by VENTX; Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4; Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6; Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4; Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6"	"25"	"0"	"90.3"	"146.5"	"150.5"	"58.2"	"131.0"	"93.0"	"139.8"	"106.5"	"172.0"	"199.7"	"259.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4W6"	"AFG3-like protein 2 OS=Homo sapiens OX=9606 GN=AFG3L2 PE=1 SV=2"	"3"	"3"	"5"	"2"	"797"	"88.5"	"8.66"	"1115.09"	"6.31"	"3"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf00004, Pf01434, Pf06480, Pf17862"	"10939"	"ENSG00000141385"	"AFG3L2"	"hsa:10939; Q6P1L0; Q9Y4W6"	"Ciliary landscape"	"Processing of SMDT1"	"2"	"1"	"132.5"	"219.4"	"256.1"	"104.0"	"246.7"	"139.4"	"247.7"	"154.7"	"247.9"	"301.5"	"435.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HC35"	"Echinoderm microtubule-associated protein-like 4 OS=Homo sapiens OX=9606 GN=EML4 PE=1 SV=3"	"3"	"2"	"3"	"2"	"981"	"108.8"	"6.40"	"311.33"	"6.30"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400, Pf03451, Pf07714"	"27436"	"ENSG00000143924"	"EML4"	"A6H8Y6; A6P4T4; A6P4V4; B2RBK3; B2RTW7; B5MCW9; hsa:27436; Q3SWW0; Q53R29; Q53TW8; Q6PJ45; Q9HC35; Q9NV40"	"Non-small cell lung cancer"	"EML4 and NUDC in mitotic spindle formation; ALK mutants bind TKIs; Nuclear events stimulated by ALK signaling in cancer"	"5"	"0"	"6.8"	"43.8"	"42.0"	"9.4"	"31.9"	"13.3"	"33.4"	"29.2"	"32.3"	"59.0"	"83.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96KR1"	"Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2"	"3"	"3"	"4"	"3"	"1074"	"116.9"	"9.04"	"646.46"	"6.29"	"2"	"2"	""	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf07528, Pf12874"	"51663"	"ENSG00000056097"	"ZFR"	"B2RNR5; hsa:51663; Q05C08; Q3B7X5; Q6P5A3; Q86UA0; Q96KR1; Q9H6V4; Q9NTI1; Q9Y687"	"Exercise-induced circadian regulation"	""	"1"	"0"	"152.4"	"213.6"	"230.6"	"133.6"	"240.9"	"165.8"	"789.7"	"635.8"	"758.7"	"878.5"	"1058.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BUK0"	"Coiled-coil-helix-coiled-coil-helix domain-containing protein 7 OS=Homo sapiens OX=9606 GN=CHCHD7 PE=1 SV=1"	"21"	"1"	"2"	"1"	"85"	"10.1"	"8.82"	"535.05"	"6.29"	"1"	"1"	"cell organization and biogenesis"	"mitochondrion"	""	""	"79145"	"ENSG00000170791"	"CHCHD7"	"A8K223; E9PBH3; hsa:79145; J3KNE9; Q7Z588; Q9BUK0"	""	"Mitochondrial protein import"	"1"	"0"	"19.7"	"29.2"	"38.5"	"25.6"	"30.4"	"18.1"	"50.9"	"44.9"	"57.8"	"81.1"	"96.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01081"	"Splicing factor U2AF 35 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF1 PE=1 SV=3"	"10"	"2"	"3"	"2"	"240"	"27.9"	"8.81"	"321.11"	"6.27"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00642"	"102724594; 7307"	"ENSG00000160201"	"U2AF1"	"hsa:102724594; hsa:7307; Q01081; Q701P4; Q71RF1"	"mRNA processing"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript"	"5"	"0"	"125.3"	"176.5"	"232.6"	"108.4"	"262.9"	"181.0"	"545.6"	"273.9"	"412.4"	"444.5"	"541.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43707"	"Alpha-actinin-4 OS=Homo sapiens OX=9606 GN=ACTN4 PE=1 SV=2"	"3"	"2"	"4"	"2"	"911"	"104.8"	"5.44"	"609.20"	"6.27"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;stress response;transport;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00307, Pf00435, Pf08726"	"81"	"ENSG00000130402; ENSG00000282844"	"ACTN4"	"A4K467; D6PXK4; hsa:81; O43707; O76048"	"Arrhythmogenic right ventricular cardiomyopathy; Primary focal segmental glomerulosclerosis (FSGS); Focal adhesion; Striated muscle contraction pathway; Ebola virus infection in host; Nephrotic syndrome; Alstrom syndrome"	"Platelet degranulation ; Nephrin family interactions"	"9"	"0"	"59.4"	"137.7"	"138.7"	"44.0"	"168.7"	"64.4"	"109.7"	"71.8"	"88.2"	"151.4"	"198.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13825"	"Methylglutaconyl-CoA hydratase, mitochondrial OS=Homo sapiens OX=9606 GN=AUH PE=1 SV=1"	"9"	"3"	"4"	"3"	"339"	"35.6"	"9.48"	"532.16"	"6.26"	"2"	"2"	"other metabolic processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00378"	"549"	"ENSG00000148090"	"AUH"	"B1ALV7; B1ALV8; hsa:549; Q13825; Q8WUE4"	"Amino acid metabolism"	"Branched-chain amino acid catabolism"	"2"	"0"	"66.8"	"157.2"	"182.7"	"57.2"	"158.9"	"83.5"	"180.6"	"152.7"	"197.1"	"388.7"	"822.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q53EL6"	"Programmed cell death protein 4 OS=Homo sapiens OX=9606 GN=PDCD4 PE=1 SV=2"	"7"	"3"	"5"	"3"	"469"	"51.7"	"5.21"	"1052.80"	"6.26"	"3"	"2"	"developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf02847"	"27250"	"ENSG00000150593"	"PDCD4"	"B2RCV4; B5ME91; hsa:27250; O15501; Q53EL6; Q5VZS6; Q6PJI5; Q8TAR5; Q99834"	"Translation inhibitors in chronically activated PDGFRA cells; A network map of Macrophage-stimulating protein (MSP) signaling; Interferon type I signaling pathways"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	"4"	"0"	"103.7"	"362.7"	"357.7"	"112.5"	"267.6"	"135.3"	"267.5"	"212.4"	"295.4"	"377.6"	"567.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8ND56"	"Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3"	"9"	"3"	"6"	"3"	"463"	"50.5"	"9.52"	"864.58"	"6.24"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;signal transduction;other biological processes"	"cytosol;cytoskeleton;other cell component"	"nucleic acid binding activity"	"Pf09532, Pf12701"	"26065"	"ENSG00000257103; ENSG00000262860"	"LSM14A"	"B4DTG6; hsa:26065; Q76LX7; Q8ND56; Q96AR3; Q96K73; Q96SN5; Q9UFR3"	""	""	"0"	"0"	"159.1"	"256.9"	"296.7"	"128.1"	"274.3"	"202.8"	"329.4"	"227.8"	"362.0"	"360.3"	"462.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08243"	"Asparagine synthetase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=ASNS PE=1 SV=4"	"4"	"3"	"5"	"3"	"561"	"64.3"	"6.86"	"834.84"	"6.23"	"3"	"2"	"other metabolic processes;stress response;other biological processes"	"cytosol"	"other molecular function"	"Pf00733, Pf13537"	"440"	"ENSG00000070669"	"ASNS"	"A4D1I8; B4DXZ1; B7ZAA9; D6W5R3; E9PCI3; E9PCX6; hsa:440; P08184; P08243; Q15666; Q549T9; Q96HD0"	"Photodynamic therapy-induced unfolded protein response; Amino acid metabolism"	"Aspartate and asparagine metabolism; Response of EIF2AK1 (HRI) to heme deficiency; ATF4 activates genes in response to endoplasmic reticulum  stress; Response of EIF2AK4 (GCN2) to amino acid deficiency"	"6"	"0"	"210.7"	"1520.4"	"1111.7"	"132.8"	"970.1"	"304.3"	"379.6"	"273.8"	"347.1"	"443.1"	"1042.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q06124"	"Tyrosine-protein phosphatase non-receptor type 11 OS=Homo sapiens OX=9606 GN=PTPN11 PE=1 SV=3"	"5"	"2"	"4"	"2"	"593"	"68.0"	"7.30"	"697.34"	"6.23"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00017, Pf00102"	"5781"	"ENSG00000179295"	"PTPN11"	"A8K1D9; hsa:5781; Q06124; Q96HD7"	"IL-5 signaling pathway; Heart development; IL-1 signaling pathway; Leptin signaling pathway; Prolactin signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; Pilocytic astrocytoma; Androgen receptor network in prostate cancer; B cell receptor signaling pathway; Interleukin-11 signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Alpha 6 beta 4 signaling pathway; IL-3 signaling pathway; Kit receptor signaling pathway; Hepatocyte growth factor receptor signaling; RAC1/PAK1/p38/MMP2 pathway; IL6 signaling pathway; Hepatitis C and hepatocellular carcinoma; VEGFA-VEGFR2 signaling; Embryonic stem cell pluripotency pathways; IL-4 signaling pathway; Ras signaling; EGF/EGFR signaling pathway; Fragile X syndrome; Cancer immunotherapy by CTLA4 blockade; Cancer immunotherapy by PD-1 blockade; Gastrin signaling pathway; Netrin-UNC5B signaling pathway; Insulin signaling; IL-2 signaling pathway; Angiotensin II receptor type 1 pathway; Kallmann syndrome; Orexin receptor pathway; GDNF signaling; Interferon type I signaling pathways; Type II interferon signaling; T-cell receptor signaling pathway"	"PIP3 activates AKT signaling; GPVI-mediated activation cascade; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Platelet sensitization by LDL; CTLA4 inhibitory signaling; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Interleukin-3, Interleukin-5 and GM-CSF signaling; PD-1 signaling; Activation of IRF3, IRF7 mediated by TBK1, IKBKE; Signal regulatory protein family interactions; Constitutive Signaling by Aberrant PI3K in Cancer; RET signaling; PI3K Cascade; Signaling by SCF-KIT; Downstream signal transduction; Tie2 Signaling; Interleukin-6 signaling; Signaling by Leptin; Regulation of IFNG signaling; Regulation of IFNA/IFNB signaling; Signaling by CSF3 (G-CSF); GAB1 signalosome; Signaling by CSF1 (M-CSF) in myeloid cells; PI-3K cascade:FGFR1; FRS-mediated FGFR1 signaling; PI-3K cascade:FGFR2; FRS-mediated FGFR2 signaling; FRS-mediated FGFR3 signaling; PI-3K cascade:FGFR3; FRS-mediated FGFR4 signaling; PI-3K cascade:FGFR4; Activated NTRK2 signals through FRS2 and FRS3; Spry regulation of FGF signaling; MAPK3 (ERK1) activation; MAPK1 (ERK2) activation; Prolactin receptor signaling; Interleukin-20 family signaling; Netrin mediated repulsion signals; Interleukin-37 signaling; PECAM1 interactions; MET activates PTPN11; STAT5 activation downstream of FLT3 ITD mutants; Regulation of RUNX1 Expression and Activity; STAT5 Activation"	"90"	"0"	"39.2"	"178.0"	"145.6"	"39.8"	"132.6"	"51.0"	"93.1"	"84.4"	"121.6"	"203.5"	"399.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NP81"	"Serine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=SARS2 PE=1 SV=1"	"6"	"2"	"4"	"2"	"518"	"58.2"	"8.13"	"714.94"	"6.23"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00587"	"54938"	"ENSG00000104835; ENSG00000283104"	"SARS2"	"A6NHW7; B4DE10; hsa:54938; Q9BVP3; Q9NP81"	""	"Mitochondrial tRNA aminoacylation"	"1"	"0"	"15.6"	"37.0"	"45.9"	"14.5"	"38.5"	"15.3"	"31.2"	"26.6"	"39.0"	"55.2"	"61.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"E9PRG8"	"Uncharacterized protein C11orf98 OS=Homo sapiens OX=9606 GN=C11orf98 PE=4 SV=2"	"17"	"2"	"4"	"2"	"123"	"14.2"	"11.53"	"608.74"	"6.22"	"2"	"2"	""	""	""	"Pf17719"	"102288414"	"ENSG00000278615"	"C11orf98"	"A0A0B4J220; E9PRG8; hsa:102288414"	""	""	"0"	"0"	"73.6"	"110.6"	"140.9"	"72.8"	"139.9"	"84.2"	"217.8"	"197.7"	"243.1"	"318.8"	"441.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WVV9"	"Heterogeneous nuclear ribonucleoprotein L-like OS=Homo sapiens OX=9606 GN=HNRNPLL PE=1 SV=1"	"7"	"3"	"5"	"2"	"542"	"60.0"	"7.72"	"689.45"	"6.21"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf11835, Pf13893"	"92906"	"ENSG00000143889"	"HNRNPLL"	"hsa:92906; Q53T80; Q5JB51; Q5JB52; Q659B9; Q8IVH5; Q8IVH6; Q8WVV9; Q96HR5"	""	""	"0"	"0"	"13.4"	"15.7"	"8.3"	"8.7"	"15.3"	"12.4"	"16.5"	"11.0"	"17.4"	"15.1"	"19.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BXP5"	"Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1"	"3"	"2"	"3"	"2"	"876"	"100.6"	"5.96"	"372.83"	"6.20"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04959, Pf12066"	"51593"	"ENSG00000087087"	"SRRT"	"A4D2E5; A4D2E6; A6NK22; B4DJL4; B4DZA6; hsa:51593; O95808; Q32MI4; Q6NT74; Q8TDQ5; Q9BWP6; Q9BXP4; Q9BXP5; Q9Y4S4"	""	"mRNA Splicing - Major Pathway; RNA polymerase II transcribes snRNA genes"	"2"	"0"	"133.1"	"261.1"	"293.7"	"115.1"	"246.6"	"143.6"	"316.0"	"219.4"	"345.1"	"378.3"	"531.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HD33"	"39S ribosomal protein L47, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL47 PE=1 SV=2"	"7"	"2"	"4"	"2"	"250"	"29.4"	"10.37"	"651.39"	"6.18"	"2"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf06984"	"57129"	"ENSG00000136522"	"MRPL47"	"hsa:57129; Q6XRG1; Q8N5D1; Q9HD33"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"134.6"	"308.6"	"293.8"	"117.4"	"245.6"	"135.8"	"162.8"	"135.6"	"202.9"	"243.6"	"358.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60828"	"Polyglutamine-binding protein 1 OS=Homo sapiens OX=9606 GN=PQBP1 PE=1 SV=1"	"7"	"2"	"4"	"2"	"265"	"30.5"	"6.33"	"675.23"	"6.17"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	""	"10084"	"ENSG00000102103"	"PQBP1"	"C9JQA1; hsa:10084; O60828; Q4VY25; Q4VY26; Q4VY27; Q4VY29; Q4VY30; Q4VY34; Q4VY35; Q4VY36; Q4VY37; Q4VY38; Q9GZP2; Q9GZU4; Q9GZZ4"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"116.3"	"186.5"	"196.3"	"91.9"	"229.8"	"120.8"	"206.9"	"163.9"	"241.0"	"306.5"	"394.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99436"	"Proteasome subunit beta type-7 OS=Homo sapiens OX=9606 GN=PSMB7 PE=1 SV=1"	"7"	"2"	"4"	"2"	"277"	"29.9"	"7.68"	"730.12"	"6.17"	"2"	"2"	"protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00227, Pf12465"	"5695"	"ENSG00000136930"	"PSMB7"	"B4E0P1; hsa:5695; Q5TBG6; Q96AG8; Q99436; Q9BWA7"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Antigen processing: Ubiquitination & Proteasome degradation; AUF1 (hnRNP D0) binds and destabilizes mRNA; MAPK6/MAPK4 signaling; Downstream TCR signaling; FCERI mediated NF-kB activation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"63"	"0"	"275.0"	"389.7"	"479.2"	"227.1"	"433.7"	"268.1"	"664.3"	"554.5"	"646.8"	"798.3"	"1277.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43852"	"Calumenin OS=Homo sapiens OX=9606 GN=CALU PE=1 SV=2"	"10"	"3"	"4"	"3"	"315"	"37.1"	"4.64"	"648.53"	"6.15"	"2"	"2"	""	"non-structural extracellular;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf13833"	"813"	"ENSG00000128595"	"CALU"	"B3KPG9; D6QS48; D6QS49; D6QS50; D6QS51; D6QS52; D6QS53; D6QS54; D6QS55; D6QS56; D6QS57; D6QS58; D6QS59; F5H1Q9; F5H879; hsa:813; O43852; O60456; Q6FHB9; Q96RL3; Q9NR43"	"NOTCH1 regulation of endothelial cell calcification; VEGFA-VEGFR2 signaling"	"Platelet degranulation ; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation"	"5"	"0"	"136.9"	"246.2"	"278.3"	"117.4"	"290.3"	"182.8"	"257.3"	"184.9"	"259.5"	"349.4"	"515.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95817"	"BAG family molecular chaperone regulator 3 OS=Homo sapiens OX=9606 GN=BAG3 PE=1 SV=3"	"4"	"2"	"3"	"2"	"575"	"61.6"	"6.95"	"393.23"	"6.15"	"1"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00397, Pf02179"	"9531"	"ENSG00000151929"	"BAG3"	"A8K5L8; hsa:9531; O95817; Q3B763; Q9NT20; Q9P120"	"Cell interactions of the pancreatic cancer microenvironment"	"Regulation of HSF1-mediated heat shock response"	"2"	"0"	"10.7"	"44.7"	"36.1"	"6.8"	"31.3"	"5.6"	"25.4"	"18.1"	"27.7"	"29.1"	"53.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BPX5"	"Actin-related protein 2/3 complex subunit 5-like protein OS=Homo sapiens OX=9606 GN=ARPC5L PE=1 SV=1"	"8"	"1"	"4"	"1"	"153"	"16.9"	"6.60"	"673.13"	"6.12"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf04699"	"81873"	"ENSG00000136950"	"ARPC5L"	"hsa:81873; Q7Z523; Q9BPX5"	"Pathogenic Escherichia coli infection; VEGFA-VEGFR2 signaling"	""	"2"	"0"	"12.0"	"30.0"	"38.6"	"16.7"	"33.8"	"17.3"	"50.7"	"60.2"	"86.8"	"134.6"	"251.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P15311"	"Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4"	"3"	"2"	"3"	"2"	"586"	"69.4"	"6.27"	"391.45"	"6.11"	"1"	"2"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf00769, Pf09379, Pf09380, Pf20492"	"7430"	"ENSG00000092820"	"EZR"	"E1P5A8; hsa:7430; P15311; P23714; Q4VX75; Q96CU8; Q9NSJ4"	"Pathogenic Escherichia coli infection; AGE/RAGE pathway; VEGFA-VEGFR2 signaling; 16p11.2 proximal deletion syndrome; CCL18 signaling pathway; Regulation of actin cytoskeleton; GDNF signaling"	"Recycling pathway of L1; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Netrin-1 signaling"	"11"	"0"	"103.7"	"178.7"	"224.3"	"107.9"	"251.2"	"136.4"	"452.3"	"355.5"	"476.5"	"628.6"	"1114.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12797"	"Aspartyl/asparaginyl beta-hydroxylase OS=Homo sapiens OX=9606 GN=ASPH PE=1 SV=3"	"3"	"2"	"4"	"2"	"758"	"85.8"	"5.01"	"721.95"	"6.10"	"2"	"2"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi"	"other molecular function"	"Pf05118, Pf05279, Pf13432"	"444"	"ENSG00000198363"	"ASPH"	"A0A0A0MSK8; A6NDF4; A6NHI2; B4DIC9; B4E2K4; B7ZM95; E5RGP5; F5H667; hsa:444; Q12797; Q6NXR7; Q8TB28; Q9H291; Q9H2C4; Q9NRI0; Q9NRI1; Q9Y4J0"	""	"Stimuli-sensing channels; Ion homeostasis"	"2"	"0"	"19.8"	"80.8"	"71.7"	"22.6"	"67.8"	"22.3"	"67.8"	"63.3"	"93.3"	"164.6"	"362.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HC38"	"Glyoxalase domain-containing protein 4 OS=Homo sapiens OX=9606 GN=GLOD4 PE=1 SV=1"	"8"	"2"	"4"	"2"	"313"	"34.8"	"5.60"	"641.06"	"6.09"	"2"	"2"	""	"mitochondrion"	""	""	"51031"	"ENSG00000167699"	"GLOD4"	"D3DTG9; D3DTH1; hsa:51031; Q96B89; Q9H3J8; Q9HC37; Q9HC38; Q9NVN1"	""	""	"0"	"0"	"5.7"	"36.8"	"21.8"	"3.0"	"29.5"	"13.4"	"12.4"	"9.4"	"11.7"	"15.6"	"28.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15226"	"NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2"	"4"	"3"	"5"	"3"	"690"	"77.6"	"8.79"	"991.43"	"6.08"	"3"	"2"	"RNA metabolism OR transcription;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01424, Pf01585"	"55922"	"ENSG00000186416"	"NKRF"	"G3V1N1; hsa:55922; O15226; Q4VC41; Q9UJ91"	"Pathogenesis of SARS-CoV-2 mediated by nsp9-nsp10 complex; Network map of SARS-CoV-2 signaling pathway"	""	"2"	"0"	"53.2"	"127.2"	"137.2"	"57.7"	"127.2"	"70.3"	"118.7"	"86.6"	"156.7"	"177.6"	"243.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P38606"	"V-type proton ATPase catalytic subunit A OS=Homo sapiens OX=9606 GN=ATP6V1A PE=1 SV=2"	"4"	"2"	"4"	"2"	"617"	"68.3"	"5.52"	"741.78"	"6.08"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf00006, Pf02874, Pf16886"	"523"	"ENSG00000114573"	"ATP6V1A"	"B2RBR8; B7Z1R5; D3DN75; hsa:523; P38606; Q53YD9; Q96DY6; Q9UHY3"	"Proximal tubule transport"	"Amino acids regulate mTORC1; ROS and RNS production in phagocytes; Insulin receptor recycling; Transferrin endocytosis and recycling; Ion channel transport"	"6"	"0"	"33.0"	"96.2"	"98.7"	"27.5"	"85.3"	"44.6"	"71.8"	"56.3"	"74.5"	"100.8"	"142.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13984"	"General transcription factor IIF subunit 2 OS=Homo sapiens OX=9606 GN=GTF2F2 PE=1 SV=2"	"10"	"2"	"4"	"2"	"249"	"28.4"	"9.23"	"712.94"	"6.07"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf02270, Pf17683"	"2963"	"ENSG00000188342"	"GTF2F2"	"A6NNS5; hsa:2963; P13984; Q5W0H3"	"Eukaryotic transcription initiation"	"mRNA Splicing - Major Pathway; Viral Messenger RNA Synthesis; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Estrogen-dependent gene expression; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM"	"33"	"0"	"13.8"	"38.8"	"35.6"	"8.2"	"33.8"	"14.6"	"48.0"	"45.7"	"57.6"	"65.9"	"115.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H939"	"Proline-serine-threonine phosphatase-interacting protein 2 OS=Homo sapiens OX=9606 GN=PSTPIP2 PE=1 SV=4"	"4"	"1"	"4"	"1"	"334"	"38.8"	"8.48"	"579.64"	"6.07"	"1"	"1"	"cell organization and biogenesis"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf00611"	"9050"	"ENSG00000152229"	"PSTPIP2"	"hsa:9050; Q9H939"	""	""	"0"	"0"	"25.9"	"27.4"	"27.4"	"18.2"	"39.9"	"38.1"	"75.8"	"46.0"	"102.2"	"142.5"	"183.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60613"	"Selenoprotein F OS=Homo sapiens OX=9606 GN=SELENOF PE=1 SV=4"	"18"	"2"	"4"	"2"	"165"	"18.1"	"5.03"	"634.47"	"6.06"	"2"	"2"	"cell organization and biogenesis;other biological processes"	"ER/Golgi"	"other molecular function"	"Pf08806"	"9403"	"ENSG00000183291"	"SELENOF"	"A0A0B4J1S4; hsa:9403; O60613; Q4GZG7; Q8WU00; Q9BS64; Q9GZW0; Q9NR01"	"Selenium metabolism / selenoproteins; Selenium micronutrient network"	""	"2"	"0"	"26.4"	"67.5"	"70.3"	"27.3"	"59.3"	"37.1"	"66.2"	"53.6"	"73.9"	"134.6"	"204.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BWU0"	"Kanadaptin OS=Homo sapiens OX=9606 GN=SLC4A1AP PE=1 SV=1"	"7"	"3"	"3"	"3"	"796"	"88.8"	"5.19"	"396.18"	"6.04"	"1"	"2"	""	"plasma membrane;other membranes;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00498"	"22950"	"ENSG00000163798"	"SLC4A1AP"	"A6NJ39; hsa:22950; Q4KMT1; Q4KMX0; Q7Z5Q9; Q9BWU0; Q9NVN2"	""	""	"0"	"0"	"34.4"	"52.0"	"71.1"	"43.6"	"71.8"	"33.5"	"85.7"	"54.2"	"97.5"	"136.5"	"139.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z2W4"	"Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3"	"2"	"2"	"4"	"2"	"902"	"101.4"	"8.40"	"566.77"	"6.03"	"2"	"2"	"stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00644, Pf02825, Pf18606, Pf18633"	"56829"	"ENSG00000105939"	"ZC3HAV1"	"A4D1R2; A4D1S4; hsa:56829; Q7Z2W4; Q8IW57; Q8TAJ3; Q96N79; Q9H8R9; Q9P0Y7"	""	"Signaling by BRAF and RAF1 fusions"	"1"	"0"	"84.6"	"155.3"	"171.5"	"82.7"	"183.1"	"97.5"	"214.7"	"147.5"	"189.7"	"235.7"	"327.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96RK4"	"Bardet-Biedl syndrome 4 protein OS=Homo sapiens OX=9606 GN=BBS4 PE=1 SV=2"	"7"	"3"	"5"	"3"	"519"	"58.2"	"7.31"	"1016.79"	"6.01"	"3"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf13181, Pf13414"	"585"	"ENSG00000140463"	"BBS4"	"B4E178; hsa:585; Q53DZ5; Q8NHU9; Q96H45; Q96RK4"	"Prader-Willi and Angelman syndrome; Ciliary landscape; Genes related to primary cilium development (based on CRISPR); Joubert syndrome; Ciliopathies; Bardet-Biedl syndrome"	"BBSome-mediated cargo-targeting to cilium"	"7"	"0"	"33.8"	"81.1"	"76.3"	"34.2"	"99.2"	"61.6"	"114.4"	"152.3"	"327.1"	"439.4"	"602.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P00568"	"Adenylate kinase isoenzyme 1 OS=Homo sapiens OX=9606 GN=AK1 PE=1 SV=3"	"14"	"2"	"2"	"2"	"194"	"21.6"	"8.63"	""	"5.99"	""	"2"	"other metabolic processes"	"cytosol;cytoskeleton;other cell component"	"kinase activity;other molecular function"	"Pf00406"	"203"	"ENSG00000106992"	"AK1"	"hsa:203; P00568; Q9BVK9; Q9UQC7"	""	"Interconversion of nucleotide di- and triphosphates"	"1"	"0"	"12.9"	"33.0"	"38.7"	"13.3"	"38.1"	"15.5"	"21.9"	"13.1"	"28.9"	"27.7"	"32.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BR76"	"Coronin-1B OS=Homo sapiens OX=9606 GN=CORO1B PE=1 SV=1"	"4"	"2"	"4"	"2"	"489"	"54.2"	"5.88"	"645.22"	"5.99"	"2"	"2"	"cell organization and biogenesis;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400, Pf08953, Pf16300"	"57175"	"ENSG00000172725"	"CORO1B"	"B2RD45; hsa:57175; Q9BR76"	""	""	"0"	"0"	"88.3"	"175.4"	"185.4"	"82.4"	"163.4"	"88.3"	"187.7"	"154.4"	"205.5"	"276.2"	"455.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13888"	"General transcription factor IIH subunit 2 OS=Homo sapiens OX=9606 GN=GTF2H2 PE=1 SV=1"	"5"	"2"	"5"	"2"	"395"	"44.4"	"6.76"	"837.43"	"5.99"	"2"	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"nucleus"	"other molecular function"	"Pf04056, Pf07975"	"2966"	"ENSG00000145736; ENSG00000275045; ENSG00000276910"	"GTF2H2"	"hsa:2966; Q13888; Q15570; Q15571; Q9BS41"	"Eukaryotic transcription initiation; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Dual Incision in GG-NER"	"33"	"0"	"106.5"	"188.5"	"211.2"	"89.8"	"202.8"	"120.6"	"213.5"	"311.4"	"574.8"	"973.9"	"1246.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WVM8"	"Sec1 family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SCFD1 PE=1 SV=4"	"4"	"2"	"4"	"2"	"642"	"72.3"	"6.27"	"705.53"	"5.97"	"2"	"2"	"stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi"	"other molecular function"	"Pf00995"	"23256"	"ENSG00000092108"	"SCFD1"	"A8K2Z5; B7Z4U7; B7Z594; hsa:23256; O60754; O94990; Q7Z529; Q8WVM8; Q9BZI3; Q9UNL3; Q9Y6A8"	""	"RHOA GTPase cycle; COPII-mediated vesicle transport"	"2"	"0"	"21.9"	"60.2"	"67.0"	"25.2"	"54.9"	"32.1"	"40.6"	"30.7"	"59.9"	"94.6"	"149.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99570"	"Phosphoinositide 3-kinase regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PIK3R4 PE=1 SV=3"	"2"	"2"	"4"	"2"	"1358"	"153.0"	"7.17"	"773.71"	"5.96"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00400"	"30849"	"ENSG00000196455"	"PIK3R4"	"hsa:30849; Q2TBF4; Q99570"	"Alzheimer's disease and miRNA effects; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Neural crest cell migration during development; Neural crest cell migration in cancer; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Osteoblast differentiation and related diseases; Ciliopathies; Insulin signaling; Autophagy; Regulation of actin cytoskeleton; Alzheimer's disease; DNA damage response (only ATM dependent)"	"SARS-CoV-2 activates/modulates innate and adaptive immune responses; Synthesis of PIPs at the Golgi membrane; Synthesis of PIPs at the early endosome membrane; Synthesis of PIPs at the late endosome membrane; PI3K Cascade; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Macroautophagy; Translation of Replicase and Assembly of the Replication Transcription Complex; Translation of Replicase and Assembly of the Replication Transcription Complex; RHO GTPases Activate NADPH Oxidases; Toll Like Receptor 9 (TLR9) Cascade"	"24"	"0"	"22.1"	"45.1"	"53.7"	"21.0"	"44.5"	"27.6"	"56.7"	"56.0"	"63.4"	"93.9"	"125.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92558"	"Wiskott-Aldrich syndrome protein family member 1 OS=Homo sapiens OX=9606 GN=WASF1 PE=1 SV=1"	"4"	"2"	"4"	"2"	"559"	"61.6"	"6.46"	"464.58"	"5.93"	"1"	"2"	"cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02205"	"8936"	"ENSG00000112290"	"WASF1"	"E1P5F2; hsa:8936; Q5SZK7; Q92558"	"VEGFA-VEGFR2 signaling; Regulation of actin cytoskeleton"	"VEGFA-VEGFR2 Pathway; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RAC1 GTPase cycle; RHO GTPases Activate WASPs and WAVEs; RAC3 GTPase cycle"	"8"	"0"	"88.7"	"193.9"	"215.4"	"79.8"	"194.9"	"107.9"	"200.1"	"143.1"	"256.6"	"318.2"	"459.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14854"	"Cytochrome c oxidase subunit 6B1 OS=Homo sapiens OX=9606 GN=COX6B1 PE=1 SV=2"	"17"	"1"	"4"	"1"	"86"	"10.2"	"7.05"	"700.27"	"5.93"	"1"	"1"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf02297"	"1340"	"ENSG00000126267"	"COX6B1"	"B2R5C9; hsa:1340; P14854; Q6IBL4"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex IV assembly"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"6"	"0"	"56.6"	"95.8"	"95.8"	"46.9"	"114.6"	"64.1"	"95.8"	"63.7"	"92.0"	"105.5"	"144.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51149"	"Ras-related protein Rab-7a OS=Homo sapiens OX=9606 GN=RAB7A PE=1 SV=1"	"10"	"2"	"4"	"2"	"207"	"23.5"	"6.70"	"765.05"	"5.93"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00071"	"7879"	"ENSG00000075785"	"RAB7A"	"A8K3V6; hsa:7879; P51149; Q9NWJ0; Q9UPB0"	"Ebola virus infection in host; Autosomal recessive osteopetrosis pathways; Intracellular trafficking proteins involved in CMT neuropathy"	"RAC1 GTPase cycle; RHOG GTPase cycle; Prevention of phagosomal-lysosomal fusion; CDC42 GTPase cycle; RHOQ GTPase cycle; RAB GEFs exchange GTP for GDP on RABs; RAB geranylgeranylation; MHC class II antigen presentation; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOD GTPase cycle; RHOJ GTPase cycle; RHOF GTPase cycle; Neutrophil degranulation; Suppression of autophagy; RHOH GTPase cycle; TBC/RABGAPs"	"20"	"0"	"86.5"	"328.7"	"276.9"	"51.7"	"178.6"	"89.6"	"125.3"	"94.9"	"145.0"	"197.9"	"349.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P01034"	"Cystatin-C OS=Homo sapiens OX=9606 GN=CST3 PE=1 SV=1"	"12"	"1"	"2"	"1"	"146"	"15.8"	"8.75"	"721.95"	"5.93"	"1"	"1"	"cell organization and biogenesis;stress response;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00031"	"1471"	"ENSG00000101439"	"CST3"	"B2R5J9; D3DW42; hsa:1471; P01034; Q6FGW9"	""	"Neutrophil degranulation; Amyloid fiber formation; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation"	"4"	"0"	"31.5"	"56.3"	"58.2"	"33.0"	"54.0"	"32.1"	"56.8"	"57.1"	"105.5"	"179.0"	"277.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95785"	"Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2"	"2"	"2"	"3"	"2"	"1651"	"178.6"	"6.86"	"296.96"	"5.92"	"1"	"2"	"RNA metabolism OR transcription;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	""	"58525"	"ENSG00000011451"	"WIZ"	"B3KVH1; B7ZM82; hsa:58525; M0QY21; O95785; Q4G0E0; Q6P6B0; Q6ZN24; Q7LDY6; Q7LDZ1; Q96IG5; Q96SQ6; Q9BUR8; Q9NPT1"	""	""	"0"	"0"	"3.6"	"12.8"	"13.3"	"3.9"	"13.1"	"6.1"	"9.4"	"11.0"	"9.5"	"17.9"	"23.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P18206"	"Vinculin OS=Homo sapiens OX=9606 GN=VCL PE=1 SV=4"	"2"	"2"	"4"	"2"	"1134"	"123.7"	"5.66"	"555.80"	"5.92"	"2"	"2"	"cell adhesion;cell organization and biogenesis;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01044"	"7414"	"ENSG00000035403"	"VCL"	"hsa:7414; P18206; Q16450; Q5SWX2; Q7Z3B8; Q8IXU7"	"Integrin-mediated cell adhesion; Primary focal segmental glomerulosclerosis (FSGS); Focal adhesion; VEGFA-VEGFR2 signaling; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Melanoma; Regulation of actin cytoskeleton"	"Platelet degranulation ; Neutrophil degranulation; Signaling by BRAF and RAF1 fusions; Signaling by ALK fusions and activated point mutants; Smooth Muscle Contraction; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants"	"18"	"0"	"26.9"	"192.9"	"144.0"	"17.8"	"128.5"	"35.6"	"69.7"	"58.2"	"87.0"	"99.1"	"184.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16822"	"Phosphoenolpyruvate carboxykinase [GTP], mitochondrial OS=Homo sapiens OX=9606 GN=PCK2 PE=1 SV=4"	"4"	"2"	"4"	"2"	"640"	"70.7"	"7.62"	"626.77"	"5.92"	"2"	"2"	"other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf00821, Pf17297"	"5106"	"ENSG00000100889; ENSG00000285241"	"PCK2"	"B4DW73; hsa:5106; O43253; Q16822; Q86U01; Q9BV62"	"Adipogenesis; Transcription factor regulation in adipogenesis; PPAR signaling pathway; PI3K-Akt signaling pathway; Krebs cycle disorders; DNA damage response (only ATM dependent)"	"Gluconeogenesis"	"7"	"0"	"5.4"	"38.0"	"24.5"	"3.9"	"23.4"	"8.4"	"11.8"	"8.2"	"13.0"	"17.4"	"33.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15334"	"Lethal(2) giant larvae protein homolog 1 OS=Homo sapiens OX=9606 GN=LLGL1 PE=1 SV=3"	"2"	"2"	"3"	"2"	"1064"	"115.3"	"6.29"	"381.17"	"5.91"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00400, Pf08366"	"3996"	"ENSG00000131899; ENSG00000284137"	"LLGL1"	"A7MBM7; hsa:3996; O00188; Q15334; Q58F11; Q86UK6"	""	""	"0"	"0"	"43.4"	"76.4"	"81.6"	"39.9"	"102.4"	"62.4"	"102.6"	"104.9"	"224.1"	"295.7"	"326.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01780"	"Exosome component 10 OS=Homo sapiens OX=9606 GN=EXOSC10 PE=1 SV=2"	"2"	"2"	"4"	"2"	"885"	"100.8"	"8.46"	"619.87"	"5.90"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00570, Pf01612, Pf08066"	"5394"	"ENSG00000171824"	"EXOSC10"	"B1AKQ0; B1AKQ1; hsa:5394; Q01780; Q15158"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"89.6"	"137.7"	"160.6"	"85.4"	"162.4"	"97.6"	"153.4"	"119.8"	"177.8"	"222.0"	"310.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQA1"	"Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1"	"4"	"1"	"4"	"1"	"342"	"36.7"	"5.17"	"539.97"	"5.90"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400"	"79084"	"ENSG00000116455"	"WDR77"	"B3KMW6; B4DP38; hsa:79084; Q3LID2; Q53FU2; Q6JZZ5; Q96GK4; Q9BQA1; Q9BWY3"	""	"RMTs methylate histone arginines; snRNP Assembly"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q00059"	"Transcription factor A, mitochondrial OS=Homo sapiens OX=9606 GN=TFAM PE=1 SV=1"	"7"	"2"	"4"	"2"	"246"	"29.1"	"9.72"	"672.61"	"5.88"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;mitochondrion;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00505, Pf09011"	"7019"	"ENSG00000108064"	"TFAM"	"A8MRB2; A9QXC6; B5BU05; hsa:7019; Q00059; Q5U0C6"	"Energy metabolism; NAD metabolism, sirtuins and aging; VEGFA-VEGFR2 signaling; Mitochondrial gene expression; Orexin receptor pathway; Sildenafil treatment"	"Mitochondrial transcription initiation; Transcriptional activation of mitochondrial biogenesis"	"8"	"0"	"101.1"	"343.6"	"301.4"	"100.3"	"279.0"	"131.3"	"365.5"	"269.1"	"433.2"	"538.4"	"814.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O96019"	"Actin-like protein 6A OS=Homo sapiens OX=9606 GN=ACTL6A PE=1 SV=1"	"6"	"2"	"4"	"2"	"429"	"47.4"	"5.60"	"642.64"	"5.86"	"2"	"2"	"cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00022"	"86"	"ENSG00000136518"	"ACTL6A"	"B3KMN1; D3DNR9; hsa:86; O96019; Q8TAE5; Q9BVS8; Q9H0W6"	"Androgen receptor network in prostate cancer; Gastric cancer network 1; Tumor suppressor activity of SMARCB1; Thermogenesis; Kleefstra syndrome"	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; RMTs methylate histone arginines; UCH proteinases; HATs acetylate histones; DNA Damage Recognition in GG-NER"	"10"	"0"	"67.9"	"71.6"	"76.7"	"60.5"	"82.4"	"85.4"	"78.3"	"52.0"	"78.0"	"54.1"	"77.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UJV9"	"Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2"	"3"	"2"	"4"	"2"	"622"	"69.8"	"6.84"	"636.21"	"5.85"	"2"	"2"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00270, Pf00271"	"51428"	"ENSG00000183258"	"DDX41"	"B2RDC8; hsa:51428; Q96BK6; Q96K05; Q9NT96; Q9NW04; Q9UJV9"	""	"mRNA Splicing - Major Pathway; Regulation of innate immune responses to cytosolic DNA; IRF3-mediated induction of type I IFN"	"4"	"0"	"82.6"	"191.0"	"224.0"	"88.1"	"190.0"	"106.8"	"263.2"	"213.6"	"264.7"	"401.6"	"583.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08237"	"ATP-dependent 6-phosphofructokinase, muscle type OS=Homo sapiens OX=9606 GN=PFKM PE=1 SV=2"	"3"	"2"	"3"	"2"	"780"	"85.1"	"7.99"	"261.31"	"5.84"	"1"	"2"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus"	"kinase activity;other molecular function"	"Pf00365"	"5213"	"ENSG00000152556"	"PFKM"	"hsa:5213; J3KNX3; P08237; Q16814; Q16815; Q6ZTT1"	"Clear cell renal cell carcinoma pathways; Aerobic glycolysis; Insulin signaling; Glycolysis and gluconeogenesis"	"Glycolysis"	"5"	"0"	"22.9"	"82.2"	"75.1"	"23.0"	"59.1"	"33.2"	"58.1"	"50.5"	"69.9"	"116.2"	"186.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NZM3"	"Intersectin-2 OS=Homo sapiens OX=9606 GN=ITSN2 PE=1 SV=3"	"1"	"2"	"4"	"2"	"1697"	"193.3"	"8.12"	"684.12"	"5.82"	"2"	"2"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00018, Pf00168, Pf00621, Pf07653, Pf12763, Pf14604, Pf16652"	"50618"	"ENSG00000198399"	"ITSN2"	"hsa:50618; O95062; Q15812; Q9HAK4; Q9NXE6; Q9NYG0; Q9NZM2; Q9NZM3; Q9ULG4"	""	"Cargo recognition for clathrin-mediated endocytosis; RHOU GTPase cycle"	"3"	"0"	"10.0"	"23.9"	"26.7"	"11.2"	"25.3"	"15.0"	"45.4"	"58.9"	"128.0"	"152.9"	"259.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13148"	"TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1"	"5"	"2"	"3"	"2"	"414"	"44.7"	"6.19"	"423.50"	"5.79"	"1"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf18694"	"23435"	"ENSG00000120948"	"TARDBP"	"A4GUK4; A4GUK5; A4GUK6; B2R629; B4DJ45; E2PU12; hsa:23435; Q13148; Q53H27; Q6FI92; Q96DJ0"	"MECP2 and associated Rett syndrome"	""	"1"	"0"	"63.9"	"213.3"	"226.3"	"85.9"	"236.5"	"104.7"	"153.9"	"97.4"	"171.8"	"204.0"	"293.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86U42"	"Polyadenylate-binding protein 2 OS=Homo sapiens OX=9606 GN=PABPN1 PE=1 SV=3"	"9"	"3"	"5"	"3"	"306"	"32.7"	"5.06"	"1150.45"	"5.79"	"3"	"2"	"RNA metabolism OR transcription;other metabolic processes;transport;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"8106"	"ENSG00000100836"	"PABPN1"	"D3DS49; hsa:8106; O43484; Q86U42"	"mRNA processing"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs; Inhibition of Host mRNA Processing and RNA Silencing"	"6"	"0"	"213.8"	"501.7"	"505.2"	"183.4"	"421.3"	"229.1"	"289.6"	"208.4"	"345.8"	"446.2"	"683.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q00796"	"Sorbitol dehydrogenase OS=Homo sapiens OX=9606 GN=SORD PE=1 SV=4"	"7"	"2"	"4"	"2"	"357"	"38.3"	"7.97"	"613.22"	"5.78"	"2"	"2"	"other metabolic processes;stress response;other biological processes"	"non-structural extracellular;other membranes;cytosol;cytoskeleton;mitochondrion"	"other molecular function"	"Pf00107, Pf08240"	"6652"	"ENSG00000140263"	"SORD"	"B2R655; B7Z3A6; hsa:6652; J3JZZ5; Q00796; Q16682; Q9UMD6"	"Disorders of fructose metabolism; Polyol pathway"	"Formation of xylulose-5-phosphate; Fructose biosynthesis"	"4"	"0"	"103.8"	"294.0"	"297.9"	"81.7"	"258.0"	"99.9"	"209.6"	"160.5"	"219.5"	"309.8"	"660.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19623"	"Spermidine synthase OS=Homo sapiens OX=9606 GN=SRM PE=1 SV=1"	"8"	"2"	"4"	"2"	"302"	"33.8"	"5.49"	"684.62"	"5.76"	"2"	"2"	"other metabolic processes;other biological processes"	"cytosol"	"other molecular function"	"Pf01564, Pf17284"	"6723"	"ENSG00000116649"	"SRM"	"B1AKP9; hsa:6723; P19623; Q15511"	"Methionine de novo and salvage pathway; Amino acid metabolism"	"Metabolism of polyamines"	"3"	"0"	"21.1"	"95.4"	"75.2"	"10.6"	"70.9"	"29.6"	"34.5"	"30.2"	"38.7"	"54.9"	"96.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TDP1"	"Ribonuclease H2 subunit C OS=Homo sapiens OX=9606 GN=RNASEH2C PE=1 SV=1"	"13"	"2"	"4"	"2"	"164"	"17.8"	"5.03"	"572.31"	"5.75"	"2"	"2"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response"	"nucleus;other cell component"	""	"Pf08615"	"84153"	"ENSG00000172922"	"RNASEH2C"	"hsa:84153; Q8TDP1; Q9H7F5"	""	""	"0"	"0"	"111.6"	"292.7"	"262.4"	"74.0"	"289.4"	"98.5"	"201.8"	"162.1"	"234.2"	"326.0"	"424.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O76003"	"Glutaredoxin-3 OS=Homo sapiens OX=9606 GN=GLRX3 PE=1 SV=2"	"7"	"2"	"4"	"2"	"335"	"37.4"	"5.39"	"581.32"	"5.75"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00085, Pf00462"	"10539"	"ENSG00000108010"	"GLRX3"	"B3KMP7; B3KMQ5; D3DRG2; hsa:10539; O76003; Q5JV01; Q96CE0; Q9P1B0; Q9P1B1"	""	"Iron uptake and transport"	"1"	"0"	"44.9"	"99.3"	"103.1"	"48.8"	"72.1"	"51.9"	"54.0"	"50.5"	"66.9"	"82.6"	"97.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5K6"	"CD2-associated protein OS=Homo sapiens OX=9606 GN=CD2AP PE=1 SV=1"	"5"	"3"	"5"	"3"	"639"	"71.4"	"6.40"	"664.47"	"5.73"	"2"	"3"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00018, Pf14604"	"23607"	"ENSG00000198087"	"CD2AP"	"A6NL34; hsa:23607; Q5VYA3; Q9UG97; Q9Y5K6"	"Primary focal segmental glomerulosclerosis (FSGS); Nephrotic syndrome; Genes controlling nephrogenesis; GDNF signaling"	"Nephrin family interactions"	"5"	"0"	"67.4"	"139.3"	"139.1"	"56.9"	"150.7"	"71.0"	"189.9"	"144.6"	"201.3"	"247.1"	"341.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N6M0"	"Deubiquitinase OTUD6B OS=Homo sapiens OX=9606 GN=OTUD6B PE=1 SV=1"	"12"	"2"	"3"	"2"	"293"	"33.8"	"6.05"	"247.00"	"5.72"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	""	"other molecular function"	"Pf02338"	"51633"	"ENSG00000155100"	"OTUD6B"	"A8K6I1; B4DEY0; hsa:51633; Q8N6M0; Q9NTA4; Q9Y387"	""	""	"0"	"0"	"26.1"	"42.3"	"38.6"	"21.3"	"56.2"	"42.3"	"63.9"	"39.5"	"43.9"	"97.3"	"77.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBF2"	"Coatomer subunit gamma-2 OS=Homo sapiens OX=9606 GN=COPG2 PE=1 SV=1"	"3"	"2"	"4"	"1"	"871"	"97.6"	"5.81"	"668.12"	"5.71"	"2"	"2"	"transport"	"other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf01602, Pf08752, Pf16381"	"26958"	"ENSG00000158623"	"COPG2"	"A6NH74; hsa:26958; Q2NLA0; Q54AC3; Q8WVW8; Q9UBF2"	""	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport"	"2"	"0"	"33.8"	"71.3"	"68.8"	"25.7"	"70.0"	"35.8"	"51.4"	"38.8"	"52.4"	"85.7"	"91.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15717"	"ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2"	"7"	"2"	"4"	"2"	"326"	"36.1"	"9.17"	"711.61"	"5.70"	"2"	"2"	"cell organization and biogenesis;transport;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"1994"	"ENSG00000066044"	"ELAVL1"	"B4DVB8; hsa:1994; Q15717; Q53XN6; Q9BTT1"	"AMP-activated protein kinase signaling; Endoderm differentiation; Pre-implantation embryo; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Gastrin signaling pathway; IL-18 signaling pathway; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; 1p36 copy number variation syndrome"	"HuR (ELAVL1) binds and stabilizes mRNA"	"10"	"0"	"111.6"	"316.6"	"300.7"	"105.3"	"243.7"	"102.8"	"154.7"	"117.7"	"204.6"	"191.6"	"318.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z392"	"Trafficking protein particle complex subunit 11 OS=Homo sapiens OX=9606 GN=TRAPPC11 PE=1 SV=2"	"3"	"3"	"6"	"3"	"1133"	"128.8"	"7.14"	"1544.01"	"5.67"	"3"	"2"	"cell organization and biogenesis;transport;other biological processes"	"cytosol;ER/Golgi;other cell component"	""	"Pf11817, Pf12742"	"60684"	"ENSG00000168538"	"TRAPPC11"	"A4QPB8; B2RCD6; hsa:60684; Q5U5I7; Q6FI73; Q7Z392; Q86T25; Q9H0L1; Q9H5K9; Q9H8Q1; Q9H9I7"	"Genes related to primary cilium development (based on CRISPR)"	"RAB GEFs exchange GTP for GDP on RABs"	"2"	"0"	"35.6"	"57.5"	"57.6"	"21.9"	"60.6"	"37.2"	"97.3"	"86.4"	"159.0"	"236.3"	"418.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WUD4"	"Coiled-coil domain-containing protein 12 OS=Homo sapiens OX=9606 GN=CCDC12 PE=1 SV=1"	"11"	"2"	"4"	"2"	"166"	"19.2"	"7.34"	"774.08"	"5.67"	"2"	"2"	""	"nucleus"	""	"Pf08315"	"151903"	"ENSG00000160799"	"CCDC12"	"hsa:151903; Q8N8I4; Q8WUD4"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"147.6"	"120.3"	"204.1"	"114.4"	"220.9"	"147.0"	"354.7"	"177.0"	"304.4"	"290.3"	"317.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BXF6"	"Rab11 family-interacting protein 5 OS=Homo sapiens OX=9606 GN=RAB11FIP5 PE=1 SV=1"	"3"	"2"	"4"	"2"	"653"	"70.4"	"9.23"	"623.03"	"5.67"	"2"	"2"	"cell-cell signaling;transport;other biological processes"	"other membranes;cytoskeleton;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00168, Pf09457"	"26056"	"ENSG00000135631"	"RAB11FIP5"	"hsa:26056; O94939; Q9BXF6; Q9P0M1"	""	""	"0"	"0"	"63.2"	"104.8"	"103.0"	"54.1"	"114.2"	"78.8"	"235.2"	"414.1"	"807.4"	"1121.6"	"1420.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15067"	"Peroxisomal acyl-coenzyme A oxidase 1 OS=Homo sapiens OX=9606 GN=ACOX1 PE=1 SV=3"	"6"	"2"	"3"	"2"	"660"	"74.4"	"8.16"	"316.92"	"5.66"	"1"	"2"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle"	"other molecular function"	"Pf01756, Pf02770, Pf14749"	"51"	"ENSG00000161533"	"ACOX1"	"A8K6X8; A8KAA0; B4DK61; F5GYQ8; hsa:51; Q12863; Q15067; Q15068; Q15101; Q16131; Q7Z3W5; Q9UD31"	"Estrogen receptor pathway; Nuclear receptors meta-pathway; PPAR signaling pathway; Eicosanoid metabolism via cyclooxygenases (COX); Eicosanoid metabolism via lipooxygenases (LOX); Omega-3 / omega-6 fatty acid synthesis"	"TYSND1 cleaves peroxisomal proteins"	"8"	"0"	"14.7"	"36.9"	"30.4"	"13.6"	"34.5"	"18.5"	"32.6"	"31.1"	"35.3"	"38.9"	"63.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01469"	"Fatty acid-binding protein 5 OS=Homo sapiens OX=9606 GN=FABP5 PE=1 SV=3"	"17"	"2"	"3"	"2"	"135"	"15.2"	"7.01"	"283.93"	"5.66"	"1"	"2"	"other metabolic processes;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf00061"	"2171"	"ENSG00000164687"	"FABP5"	"B2R4K0; hsa:2171; Q01469"	"PPAR signaling pathway; Fatty acid transporters"	"Neutrophil degranulation; Triglyceride catabolism; Signaling by Retinoic Acid"	"5"	"0"	"54.6"	"283.7"	"420.2"	"33.2"	"144.5"	"66.2"	"188.4"	"145.9"	"299.4"	"332.8"	"494.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BTZ2"	"Dehydrogenase/reductase SDR family member 4 OS=Homo sapiens OX=9606 GN=DHRS4 PE=1 SV=3"	"5"	"1"	"4"	"1"	"278"	"29.5"	"8.56"	"714.77"	"5.65"	"1"	"1"	"other metabolic processes;other biological processes"	"other membranes;cytosol;mitochondrion;ER/Golgi;nucleus;other cytoplasmic organelle"	"other molecular function"	"Pf13561"	"10901"	"ENSG00000157326; ENSG00000284807"	"DHRS4"	"B2RB10; B7WNS9; D3YTB8; E2QRL8; hsa:10901; O95162; Q20CR0; Q2LC19; Q2LE81; Q58IU4; Q6E0Y1; Q6UWU3; Q71UQ6; Q8TD03; Q9BTZ2; Q9H3N5; Q9NV08"	""	"Peroxisomal protein import; RA biosynthesis pathway"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IXQ4"	"GPALPP motifs-containing protein 1 OS=Homo sapiens OX=9606 GN=GPALPP1 PE=1 SV=1"	"6"	"2"	"4"	"2"	"340"	"38.1"	"5.41"	"614.19"	"5.64"	"2"	"2"	""	""	""	"Pf12572"	"55425"	"ENSG00000133114"	"GPALPP1"	"A8K8X8; hsa:55425; Q05BX8; Q05D87; Q5T3Z3; Q5T3Z5; Q8IXQ4; Q9C0F9; Q9H2R0; Q9P0W6"	""	""	"0"	"0"	"112.2"	"167.5"	"185.1"	"107.2"	"214.1"	"132.0"	"426.5"	"250.7"	"389.6"	"413.2"	"586.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2S7"	"Polymerase delta-interacting protein 2 OS=Homo sapiens OX=9606 GN=POLDIP2 PE=1 SV=1"	"6"	"2"	"4"	"2"	"368"	"42.0"	"8.63"	"668.42"	"5.63"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytoskeleton;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity"	"Pf04379, Pf08755"	"26073"	"ENSG00000004142"	"POLDIP2"	"B2R846; hsa:26073; Q96JE4; Q9Y2S7"	""	""	"0"	"0"	"79.8"	"158.4"	"130.5"	"55.4"	"128.8"	"71.8"	"101.1"	"86.6"	"112.0"	"120.2"	"166.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UNH7"	"Sorting nexin-6 OS=Homo sapiens OX=9606 GN=SNX6 PE=1 SV=1"	"5"	"2"	"4"	"2"	"406"	"46.6"	"6.16"	"655.28"	"5.63"	"2"	"2"	"transport;other biological processes"	"other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00787, Pf09325"	"58533"	"ENSG00000129515"	"SNX6"	"C0H5W9; hsa:58533; Q9UNH7; Q9Y449"	""	""	"0"	"0"	"19.5"	"55.9"	"52.2"	"17.1"	"47.9"	"20.3"	"54.9"	"43.7"	"50.8"	"68.8"	"109.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UN37"	"Vacuolar protein sorting-associated protein 4A OS=Homo sapiens OX=9606 GN=VPS4A PE=1 SV=1"	"8"	"3"	"5"	"3"	"437"	"48.9"	"7.80"	"907.24"	"5.62"	"3"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00004, Pf04212, Pf09336, Pf17862"	"27183"	"ENSG00000132612"	"VPS4A"	"B2RCB7; hsa:27183; Q8TF07; Q9UI03; Q9UN37; Q9Y582"	"Ebola virus infection in host; Ciliary landscape"	"Budding and maturation of HIV virion; Endosomal Sorting Complex Required For Transport (ESCRT); HCMV Late Events; Sealing of the nuclear envelope (NE) by ESCRT-III"	"6"	"0"	"46.1"	"227.6"	"181.8"	"30.2"	"115.2"	"57.5"	"62.1"	"49.5"	"68.2"	"89.0"	"178.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04632"	"Calpain small subunit 1 OS=Homo sapiens OX=9606 GN=CAPNS1 PE=1 SV=1"	"15"	"2"	"3"	"2"	"268"	"28.3"	"5.20"	"332.47"	"5.62"	"1"	"2"	"protein metabolism;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	""	"826"	"ENSG00000126247"	"CAPNS1"	"A8K0P1; hsa:826; P04632; Q8WTX3; Q96EW0"	"Integrin-mediated cell adhesion"	"Formation of the cornified envelope; Degradation of the extracellular matrix; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61006"	"Ras-related protein Rab-8A OS=Homo sapiens OX=9606 GN=RAB8A PE=1 SV=1"	"9"	"2"	"4"	"1"	"207"	"23.7"	"9.07"	"637.18"	"5.58"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00071"	"4218"	"ENSG00000167461"	"RAB8A"	"B4DEK7; hsa:4218; P24407; P61006; Q6FHV5"	"Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Ciliary landscape; Joubert syndrome; 10q11.21q11.23 copy number variation syndrome"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; RAB geranylgeranylation; RAB GEFs exchange GTP for GDP on RABs; Regulation of PLK1 Activity at G2/M Transition; Anchoring of the basal body to the plasma membrane; VxPx cargo-targeting to cilium; TBC/RABGAPs"	"11"	"0"	"71.6"	"267.1"	"220.6"	"58.0"	"188.9"	"94.6"	"138.8"	"123.0"	"206.2"	"279.0"	"411.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z478"	"ATP-dependent RNA helicase DHX29 OS=Homo sapiens OX=9606 GN=DHX29 PE=1 SV=2"	"4"	"4"	"7"	"4"	"1369"	"155.1"	"8.09"	"1274.37"	"5.56"	"4"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"54505"	"ENSG00000067248"	"DHX29"	"hsa:54505; O75549; Q63HN0; Q63HN3; Q7Z478; Q8IWW2; Q8N3A1; Q9UMH2"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"72.8"	"132.1"	"121.6"	"62.3"	"125.9"	"56.7"	"226.3"	"165.7"	"255.6"	"305.0"	"465.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15003"	"Condensin complex subunit 2 OS=Homo sapiens OX=9606 GN=NCAPH PE=1 SV=3"	"6"	"4"	"6"	"4"	"741"	"82.5"	"5.06"	"1148.08"	"5.56"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf05786"	"23397"	"ENSG00000121152"	"NCAPH"	"B4E189; hsa:23397; Q15003; Q8TB87"	"2q11.2 copy number variation syndrome"	"Condensation of Prometaphase Chromosomes"	"2"	"0"	"38.7"	"90.1"	"98.0"	"32.8"	"103.0"	"72.0"	"106.2"	"84.3"	"118.5"	"146.0"	"202.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N8S7"	"Protein enabled homolog OS=Homo sapiens OX=9606 GN=ENAH PE=1 SV=2"	"4"	"2"	"3"	"2"	"591"	"66.5"	"6.93"	"846.80"	"5.53"	"2"	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00568, Pf08776"	"55740"	"ENSG00000154380"	"ENAH"	"D0PQI2; hsa:55740; Q502W5; Q5T5M7; Q5VTQ9; Q5VTR0; Q8N8S7; Q9NVF3; Q9UFB8"	"Regulation of actin cytoskeleton"	"Generation of second messenger molecules; Signaling by ROBO receptors"	"3"	"0"	"100.6"	"327.7"	"347.8"	"88.9"	"301.3"	"125.1"	"250.2"	"130.7"	"253.6"	"299.0"	"461.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UHB9"	"Signal recognition particle subunit SRP68 OS=Homo sapiens OX=9606 GN=SRP68 PE=1 SV=2"	"6"	"3"	"5"	"3"	"627"	"70.7"	"8.56"	"566.41"	"5.53"	"2"	"3"	"transport;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf16969"	"6730"	"ENSG00000167881"	"SRP68"	"B3KUU5; B3KWY7; G3V1U4; hsa:6730; Q8NCJ4; Q8WUK2; Q9UHB9"	""	"SRP-dependent cotranslational protein targeting to membrane"	"1"	"0"	"103.7"	"289.0"	"269.3"	"85.2"	"241.0"	"113.9"	"233.6"	"179.1"	"254.5"	"359.8"	"527.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13596"	"Sorting nexin-1 OS=Homo sapiens OX=9606 GN=SNX1 PE=1 SV=3"	"4"	"2"	"3"	"2"	"522"	"59.0"	"5.15"	"283.66"	"5.52"	"1"	"2"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00787, Pf03700, Pf09325"	"6642"	"ENSG00000028528"	"SNX1"	"A6NM19; A8K6T7; H0Y2M5; hsa:6642; O60750; O60751; Q13596; Q6ZRJ8"	""	""	"0"	"0"	"17.2"	"57.9"	"47.3"	"20.0"	"37.1"	"22.9"	"48.2"	"36.2"	"52.4"	"67.0"	"90.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92900"	"Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2"	"2"	"2"	"4"	"2"	"1129"	"124.3"	"6.61"	"756.27"	"5.52"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09416, Pf13086, Pf13087, Pf18141"	"5976"	"ENSG00000005007"	"UPF1"	"hsa:5976; O00239; O43343; Q86Z25; Q92842; Q92900"	"Pathophysiological roles of DUX4 in FSHD1"	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"3"	"0"	"66.4"	"189.8"	"158.8"	"51.8"	"142.7"	"78.5"	"156.3"	"120.7"	"176.6"	"234.5"	"346.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11766"	"Alcohol dehydrogenase class-3 OS=Homo sapiens OX=9606 GN=ADH5 PE=1 SV=4"	"6"	"3"	"5"	"3"	"374"	"39.7"	"7.49"	"980.80"	"5.52"	"3"	"2"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf00107, Pf08240"	"128"	"ENSG00000197894"	"ADH5"	"hsa:128; P11766; Q6FHR2"	"Folate-alcohol and cancer pathway hypotheses; Amino acid metabolism"	"Ethanol oxidation"	"3"	"0"	"186.6"	"1321.2"	"1107.7"	"91.6"	"907.7"	"264.8"	"339.4"	"232.1"	"306.0"	"422.8"	"938.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60231"	"Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2"	"3"	"2"	"4"	"2"	"1041"	"119.2"	"6.80"	"559.08"	"5.51"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"8449"	"ENSG00000204560; ENSG00000206486; ENSG00000226171; ENSG00000231377; ENSG00000233049; ENSG00000233418; ENSG00000233561"	"DHX16"	"hsa:8449; O60231; O60322; Q5JP45; Q969X7; Q96QC1"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"19.0"	"47.3"	"45.0"	"18.6"	"40.8"	"17.4"	"42.8"	"30.4"	"45.8"	"55.7"	"79.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14684"	"Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3"	"3"	"2"	"4"	"2"	"758"	"84.4"	"9.76"	"593.50"	"5.50"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf05997"	"23076"	"ENSG00000160208"	"RRP1B"	"hsa:23076; Q14684; Q8TBZ4"	""	""	"0"	"0"	"98.7"	"133.6"	"130.5"	"81.5"	"127.7"	"79.6"	"363.1"	"276.3"	"361.2"	"380.9"	"517.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13616"	"Cullin-1 OS=Homo sapiens OX=9606 GN=CUL1 PE=1 SV=2"	"2"	"2"	"3"	"2"	"776"	"89.6"	"8.00"	"296.06"	"5.50"	"1"	"2"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00888, Pf10557"	"8454"	"ENSG00000055130"	"CUL1"	"D3DWG3; hsa:8454; O60719; Q08AL6; Q13616; Q8IYW1"	"Cell cycle; TNF-alpha signaling pathway; Parkin-ubiquitin proteasomal system pathway; Apoptosis-related network due to altered Notch3 in ovarian cancer; Glucocorticoid receptor pathway; Nuclear receptors meta-pathway; Pleural mesothelioma; Notch signaling pathway"	"Neddylation; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; SCF-beta-TrCP mediated degradation of Emi1; Degradation of beta-catenin by the destruction complex; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; NIK-->noncanonical NF-kB signaling; Orc1 removal from chromatin; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; SCF(Skp2)-mediated degradation of p27/p21; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Regulation of PLK1 Activity at G2/M Transition; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Circadian Clock; Cyclin D associated events in G1; Regulation of BACH1 activity; MAP3K8 (TPL2)-dependent MAPK1/3 activation; NOTCH1 Intracellular Domain Regulates Transcription; Prolactin receptor signaling; Iron uptake and transport; Nuclear events stimulated by ALK signaling in cancer; Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling"	"40"	"0"	"116.7"	"300.7"	"284.0"	"102.0"	"257.2"	"140.8"	"286.2"	"272.1"	"331.6"	"537.4"	"1282.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7KZ85"	"Transcription elongation factor SPT6 OS=Homo sapiens OX=9606 GN=SUPT6H PE=1 SV=2"	"2"	"2"	"3"	"2"	"1726"	"198.9"	"4.91"	"317.03"	"5.49"	"1"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00575, Pf14632, Pf14633, Pf14635, Pf14639, Pf14641, Pf17674"	"6830"	"ENSG00000109111"	"SUPT6H"	"A7E2B4; hsa:6830; Q15737; Q6GMQ4; Q7KYW9; Q7KZ85; Q7LDK4; Q8N526; Q92775; Q96AH3; Q9BTH9; Q9BTI2"	""	"Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P39656"	"Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4"	"4"	"2"	"3"	"2"	"456"	"50.8"	"6.55"	"322.24"	"5.48"	"1"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity"	"Pf03345"	"1650"	"ENSG00000244038"	"DDOST"	"B2RDQ4; B4DJE3; B4DLI2; hsa:1650; O43244; P39656; Q5VWA5; Q8NI93; Q9BUI2"	"AGE/RAGE pathway; N-glycan biosynthesis"	"Neutrophil degranulation; SRP-dependent cotranslational protein targeting to membrane; Advanced glycosylation endproduct receptor signaling; Asparagine N-linked glycosylation; Maturation of spike protein"	"7"	"0"	"91.7"	"304.5"	"277.0"	"96.9"	"245.1"	"112.7"	"155.1"	"126.4"	"172.5"	"293.1"	"498.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92796"	"Disks large homolog 3 OS=Homo sapiens OX=9606 GN=DLG3 PE=1 SV=2"	"3"	"2"	"3"	"2"	"817"	"90.3"	"7.03"	"758.02"	"5.48"	"2"	"1"	"cell-cell signaling;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00018, Pf00595, Pf00625, Pf10600"	"1741"	"ENSG00000082458"	"DLG3"	"B4E0H1; D3DVU5; hsa:1741; Q5JUW6; Q5JUW7; Q92796; Q9ULI8"	""	"Assembly and cell surface presentation of NMDA receptors; RAF/MAP kinase cascade; Neurexins and neuroligins; Ras activation upon Ca2+ influx through NMDA receptor; Unblocking of NMDA receptors, glutamate binding and activation; Synaptic adhesion-like molecules; Negative regulation of NMDA receptor-mediated neuronal transmission; Long-term potentiation; NrCAM interactions; Activation of Ca-permeable Kainate Receptor"	"10"	"0"	"63.7"	"128.6"	"129.4"	"54.9"	"117.7"	"82.4"	"106.0"	"98.4"	"179.9"	"468.2"	"777.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NTM9"	"Copper homeostasis protein cutC homolog OS=Homo sapiens OX=9606 GN=CUTC PE=1 SV=1"	"13"	"3"	"5"	"3"	"273"	"29.3"	"8.18"	"809.22"	"5.47"	"3"	"2"	"cell organization and biogenesis;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf03932"	"51076"	"ENSG00000119929"	"CUTC"	"hsa:51076; Q5TCZ8; Q9NTM9; Q9Y321"	""	"Ion transport by P-type ATPases"	"1"	"0"	"62.6"	"141.7"	"151.4"	"61.5"	"129.3"	"81.0"	"240.0"	"165.3"	"239.2"	"304.0"	"434.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43809"	"Cleavage and polyadenylation specificity factor subunit 5 OS=Homo sapiens OX=9606 GN=NUDT21 PE=1 SV=1"	"7"	"2"	"4"	"2"	"227"	"26.2"	"8.82"	"615.57"	"5.46"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13869"	"11051"	"ENSG00000167005"	"NUDT21"	"hsa:11051; O43809; Q6IB85; Q6NE84"	"mRNA processing"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"5"	"0"	"249.4"	"489.7"	"454.9"	"201.2"	"397.4"	"229.7"	"569.4"	"485.7"	"723.5"	"740.3"	"959.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H2K8"	"Serine/threonine-protein kinase TAO3 OS=Homo sapiens OX=9606 GN=TAOK3 PE=1 SV=2"	"2"	"2"	"4"	"1"	"898"	"105.3"	"7.30"	"617.61"	"5.45"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069"	"51347"	"ENSG00000135090"	"TAOK3"	"hsa:51347; Q658N1; Q8IUM4; Q9H2K8; Q9HC79; Q9NZM9; Q9UHG7"	"MAPK signaling pathway"	"RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle"	"4"	"0"	"16.1"	"29.4"	"29.7"	"16.4"	"28.1"	"16.6"	"45.5"	"37.9"	"65.3"	"168.3"	"338.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13861"	"cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2"	"4"	"2"	"3"	"2"	"404"	"45.5"	"5.07"	"381.81"	"5.45"	"1"	"2"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00027, Pf02197"	"5576"	"ENSG00000114302"	"PRKAR2A"	"hsa:5576; P13861; Q16823; Q9BUB1"	"Myometrial relaxation and contraction pathways; G protein signaling pathways; Lipid metabolism pathway; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; GDNF signaling; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Factors involved in megakaryocyte development and platelet production; FCGR3A-mediated IL10 synthesis; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Vasopressin regulates renal water homeostasis via Aquaporins; PKA activation; PKA activation in glucagon signalling; Hedgehog 'off' state; DARPP-32 events; CREB1 phosphorylation through the activation of Adenylate Cyclase; ROBO receptors bind AKAP5"	"20"	"0"	"56.8"	"335.1"	"264.7"	"66.9"	"198.9"	"75.3"	"123.2"	"106.4"	"134.9"	"240.0"	"455.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15555"	"Microtubule-associated protein RP/EB family member 2 OS=Homo sapiens OX=9606 GN=MAPRE2 PE=1 SV=1"	"12"	"2"	"3"	"2"	"327"	"37.0"	"5.57"	"284.88"	"5.45"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf03271"	"10982"	"ENSG00000166974"	"MAPRE2"	"B2RE21; B3KR39; B4DJV4; B7Z2L3; E9PHR3; F5H1V8; G5E9I6; hsa:10982; Q15555; Q9UQ33"	"Ciliary landscape"	""	"1"	"0"	"48.6"	"129.9"	"131.7"	"41.3"	"133.6"	"63.3"	"91.7"	"63.1"	"208.9"	"240.6"	"309.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WWY3"	"U4/U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2"	"5"	"3"	"4"	"3"	"499"	"55.4"	"5.78"	"663.74"	"5.45"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01798, Pf09785"	"26121"	"ENSG00000105618; ENSG00000274144; ENSG00000274651; ENSG00000274894; ENSG00000275117; ENSG00000275885; ENSG00000276421; ENSG00000277154; ENSG00000277707; ENSG00000277953"	"PRPF31"	"E7ESA8; F1T0A4; F1T0A5; hsa:26121; Q17RB4; Q8N7F9; Q8WWY3; Q9H271; Q9Y439"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"196.1"	"296.6"	"293.6"	"167.2"	"307.7"	"175.3"	"676.3"	"473.2"	"701.1"	"762.0"	"1067.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99575"	"Ribonucleases P/MRP protein subunit POP1 OS=Homo sapiens OX=9606 GN=POP1 PE=1 SV=2"	"3"	"2"	"3"	"2"	"1024"	"114.6"	"9.22"	"268.49"	"5.45"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06978, Pf08170"	"10940"	"ENSG00000104356"	"POP1"	"A8K5W9; hsa:10940; Q15037; Q99575"	""	"tRNA processing in the nucleus"	"1"	"0"	"42.4"	"96.5"	"87.2"	"36.6"	"83.2"	"38.2"	"74.5"	"66.8"	"78.3"	"125.3"	"179.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5L4"	"Mitochondrial import inner membrane translocase subunit Tim13 OS=Homo sapiens OX=9606 GN=TIMM13 PE=1 SV=1"	"12"	"1"	"4"	"1"	"95"	"10.5"	"8.18"	"513.50"	"5.43"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf02953"	"26517"	"ENSG00000099800"	"TIMM13"	"hsa:26517; P62206; Q9UHL8; Q9WTL1; Q9Y5L4"	""	"Mitochondrial protein import"	"1"	"0"	"8.7"	"35.2"	"35.8"	"15.2"	"29.2"	"15.1"	"38.6"	"46.6"	"80.6"	"165.3"	"383.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BYD6"	"39S ribosomal protein L1, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL1 PE=1 SV=2"	"14"	"3"	"4"	"3"	"325"	"36.9"	"8.78"	"821.17"	"5.43"	"2"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00687"	"65008"	"ENSG00000169288"	"MRPL1"	"A6NG03; hsa:65008; Q4W5B8; Q6IAG4; Q96BW3; Q9BYD6; Q9H793; Q9NRL5"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"67.2"	"122.8"	"111.3"	"64.6"	"138.8"	"78.5"	"151.3"	"96.9"	"154.9"	"186.0"	"318.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WYA6"	"Beta-catenin-like protein 1 OS=Homo sapiens OX=9606 GN=CTNNBL1 PE=1 SV=1"	"3"	"2"	"4"	"2"	"563"	"65.1"	"5.05"	"583.78"	"5.41"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf08216"	"56259"	"ENSG00000132792"	"CTNNBL1"	"B4DE16; hsa:56259; Q0VAL9; Q0VAM0; Q53HI8; Q5JWZ2; Q5JWZ3; Q5JWZ7; Q5JWZ8; Q8N454; Q8NCL2; Q8TBD6; Q8WYA6; Q96KD2; Q9H7A5; Q9NQF9; Q9NTX0; Q9Y3M7"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"55.1"	"146.7"	"134.3"	"48.0"	"131.7"	"68.6"	"204.3"	"165.2"	"274.8"	"369.1"	"484.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14980"	"Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1"	"2"	"2"	"4"	"2"	"1071"	"123.3"	"6.06"	"676.05"	"5.40"	"2"	"2"	"other metabolic processes;transport;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03810, Pf08389, Pf08767, Pf18777, Pf18784, Pf18787"	"7514"	"ENSG00000082898"	"XPO1"	"A6NL14; A8K1K5; D6W5E2; hsa:7514; O14980; Q63HP8; Q68CP3; Q99433"	"eIF5A regulation in response to inhibition of the nuclear export system; 22q11.2 copy number variation syndrome"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; MAPK6/MAPK4 signaling; NPAS4 regulates expression of target genes; Rev-mediated nuclear export of HIV RNA; NEP/NS2 Interacts with the Cellular Export Machinery; Heme signaling; Deactivation of the beta-catenin transactivating complex; Estrogen-dependent nuclear events downstream of ESR-membrane signaling; Downregulation of TGF-beta receptor signaling; HuR (ELAVL1) binds and stabilizes mRNA; Cyclin A/B1/B2 associated events during G2/M transition"	"18"	"0"	"22.2"	"123.9"	"102.1"	"25.8"	"70.5"	"32.9"	"31.7"	"17.6"	"28.3"	"31.5"	"74.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UI30"	"Multifunctional methyltransferase subunit TRM112-like protein OS=Homo sapiens OX=9606 GN=TRMT112 PE=1 SV=1"	"27"	"2"	"3"	"2"	"125"	"14.2"	"5.26"	"445.46"	"5.40"	"1"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf03966"	"51504"	"ENSG00000173113"	"TRMT112"	"B2R539; hsa:51504; J3KNG5; Q3MHC7; Q8N2Z4; Q9UI30"	""	"Eukaryotic Translation Termination; rRNA modification in the nucleus and cytosol; tRNA modification in the nucleus and cytosol; Methylation"	"4"	"0"	"28.6"	"77.0"	"69.6"	"22.4"	"64.0"	"30.1"	"39.6"	"36.9"	"49.6"	"66.8"	"109.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2R9"	"28S ribosomal protein S7, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS7 PE=1 SV=2"	"9"	"2"	"4"	"2"	"242"	"28.1"	"9.99"	"538.84"	"5.39"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00177"	"51081"	"ENSG00000125445"	"MRPS7"	"B2R9N5; hsa:51081; Q53GD6; Q9Y2R9"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"13.8"	"33.6"	"32.7"	"14.9"	"33.9"	"18.1"	"23.1"	"19.0"	"25.0"	"34.8"	"48.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50213"	"Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3A PE=1 SV=1"	"4"	"2"	"4"	"2"	"366"	"39.6"	"6.92"	"531.72"	"5.39"	"2"	"2"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00180"	"3419"	"ENSG00000166411"	"IDH3A"	"D3DW83; hsa:3419; P50213; Q9H3X0"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Metabolic reprogramming in colon cancer; TCA cycle (aka Krebs or citric acid cycle)"	"Citric acid cycle (TCA cycle)"	"4"	"0"	"115.6"	"327.9"	"292.9"	"94.6"	"284.3"	"101.8"	"198.3"	"156.6"	"248.4"	"248.1"	"428.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61970"	"Nuclear transport factor 2 OS=Homo sapiens OX=9606 GN=NUTF2 PE=1 SV=1"	"19"	"2"	"4"	"2"	"127"	"14.5"	"5.38"	"607.60"	"5.38"	"2"	"2"	"transport;other biological processes"	"other membranes;cytosol;nucleus"	"other molecular function"	"Pf02136"	"10204"	"ENSG00000102898"	"NUTF2"	"B2R4G7; hsa:10204; P13662; P61970; Q6IB67"	""	""	"0"	"0"	"92.1"	"759.5"	"630.8"	"52.4"	"511.1"	"171.8"	"159.3"	"111.2"	"161.7"	"209.8"	"564.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H9B4"	"Sideroflexin-1 OS=Homo sapiens OX=9606 GN=SFXN1 PE=1 SV=4"	"6"	"2"	"4"	"2"	"322"	"35.6"	"9.07"	"585.08"	"5.38"	"2"	"2"	"other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity"	"Pf03820"	"94081"	"ENSG00000164466"	"SFXN1"	"B3KPW3; D3DQN2; hsa:94081; Q9H9B4; Q9HA53"	""	""	"0"	"0"	"68.4"	"322.5"	"259.4"	"50.4"	"212.1"	"71.2"	"152.7"	"115.9"	"246.7"	"252.9"	"404.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q08752"	"Peptidyl-prolyl cis-trans isomerase D OS=Homo sapiens OX=9606 GN=PPID PE=1 SV=3"	"7"	"3"	"5"	"2"	"370"	"40.7"	"7.21"	"965.37"	"5.35"	"3"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00160, Pf13176"	"5481"	"ENSG00000171497"	"PPID"	"B2R9V2; hsa:5481; Q08752"	"Alzheimer's disease and miRNA effects; NO/cGMP/PKG mediated neuroprotection; Alzheimer's disease"	"ESR-mediated signaling"	"4"	"0"	"85.5"	"304.8"	"263.0"	"54.7"	"231.2"	"101.1"	"180.4"	"189.7"	"223.7"	"313.6"	"486.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23258"	"Tubulin gamma-1 chain OS=Homo sapiens OX=9606 GN=TUBG1 PE=1 SV=2"	"8"	"3"	"6"	"3"	"451"	"51.1"	"6.14"	"1321.79"	"5.35"	"3"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis"	"cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00091, Pf03953"	"7283"	"ENSG00000131462"	"TUBG1"	"hsa:7283; P23258; Q53X79; Q9BW59"	"Alstrom syndrome"	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"8"	"0"	"30.0"	"83.3"	"82.7"	"38.0"	"73.4"	"33.8"	"116.0"	"123.0"	"219.2"	"452.3"	"932.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07339"	"Cathepsin D OS=Homo sapiens OX=9606 GN=CTSD PE=1 SV=1"	"2"	"1"	"4"	"1"	"412"	"44.5"	"6.54"	"883.86"	"5.33"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"other membranes;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00026, Pf07966"	"1509"	"ENSG00000117984"	"CTSD"	"hsa:1509; P07339; Q6IB57"	"Prolactin signaling pathway"	"MHC class II antigen presentation; Collagen degradation; Neutrophil degranulation; Estrogen-dependent gene expression; Insulin receptor recycling; Metabolism of Angiotensinogen to Angiotensins"	"7"	"0"	"67.5"	"137.4"	"150.4"	"41.3"	"106.5"	"65.2"	"87.2"	"63.3"	"83.9"	"95.3"	"153.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75414"	"Nucleoside diphosphate kinase 6 OS=Homo sapiens OX=9606 GN=NME6 PE=1 SV=3"	"12"	"2"	"4"	"2"	"186"	"21.1"	"8.32"	"523.75"	"5.31"	"2"	"2"	"other metabolic processes;other biological processes"	"mitochondrion"	"kinase activity;other molecular function"	"Pf00334"	"10201"	"ENSG00000172113"	"NME6"	"B4DGW7; B4DM99; hsa:10201; O75414; Q53HM5; Q96E73; Q9BQ63"	"Pyrimidine metabolism"	""	"1"	"0"	"58.5"	"136.9"	"112.3"	"54.0"	"114.6"	"51.1"	"140.8"	"143.5"	"196.9"	"282.1"	"371.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01433"	"AMP deaminase 2 OS=Homo sapiens OX=9606 GN=AMPD2 PE=1 SV=2"	"1"	"1"	"4"	"1"	"879"	"100.6"	"6.93"	"582.29"	"5.30"	"1"	"1"	"other metabolic processes;other biological processes"	"cytosol"	"other molecular function"	"Pf19326"	"271"	"ENSG00000116337"	"AMPD2"	"B4DK50; B4DZI5; E9PNG0; hsa:271; Q01433; Q14856; Q14857; Q16686; Q16687; Q16688; Q16729; Q5T693; Q5T695; Q96IA1; Q9UDX8; Q9UDX9; Q9UMU4"	""	"Purine salvage"	"1"	"0"	"52.2"	"150.9"	"141.6"	"59.8"	"132.5"	"72.1"	"144.2"	"191.1"	"266.9"	"417.7"	"535.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N1F7"	"Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2"	"2"	"2"	"3"	"2"	"819"	"93.4"	"5.72"	"260.91"	"5.28"	"1"	"2"	"cell organization and biogenesis;other metabolic processes;transport;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus"	"other molecular function"	"Pf04097"	"9688"	"ENSG00000102900"	"NUP93"	"B3KPQ8; hsa:9688; Q14705; Q8N1F7"	""	"SUMOylation of DNA replication proteins; Regulation of HSF1-mediated heat shock response; HCMV Early Events; Transport of Mature mRNA derived from an Intron-Containing Transcript; HCMV Late Events; Transcriptional regulation by small RNAs; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Postmitotic nuclear pore complex (NPC) reformation"	"29"	"0"	"80.5"	"186.3"	"165.2"	"49.4"	"166.2"	"79.7"	"109.5"	"95.0"	"151.1"	"201.2"	"324.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P26196"	"Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2"	"6"	"3"	"6"	"3"	"483"	"54.4"	"8.66"	"1282.72"	"5.28"	"3"	"2"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"1656"	"ENSG00000110367"	"DDX6"	"hsa:1656; P26196; Q5D048"	""	"mRNA decay by 5' to 3' exoribonuclease"	"1"	"0"	"277.9"	"556.9"	"616.4"	"246.7"	"596.9"	"344.9"	"742.1"	"468.1"	"697.2"	"827.6"	"1263.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82673"	"28S ribosomal protein S35, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS35 PE=1 SV=1"	"3"	"1"	"4"	"1"	"323"	"36.8"	"8.24"	"638.27"	"5.27"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf10213"	"60488"	"ENSG00000061794"	"MRPS35"	"hsa:60488; P82673; Q32LZ1; Q6P4C6; Q7L1M6; Q8NBP4; Q96AI0; Q9H044; Q9HC14; Q9P1R5"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"20.1"	"40.6"	"50.1"	"24.0"	"57.5"	"23.6"	"29.5"	"24.9"	"34.4"	"46.5"	"55.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95793"	"Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2"	"5"	"3"	"5"	"3"	"577"	"63.1"	"9.44"	"871.25"	"5.27"	"3"	"2"	"cell organization and biogenesis;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00035, Pf16482"	"6780"	"ENSG00000124214"	"STAU1"	"A8K9Z4; E1P5Y1; E1P608; hsa:6780; O95793; Q5JW29; Q6GTM4; Q9H5B4; Q9H5B5; Q9Y3Q2"	""	""	"0"	"0"	"19.1"	"44.1"	"53.1"	"12.2"	"58.7"	"27.9"	"52.2"	"38.1"	"56.5"	"85.8"	"103.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46087"	"Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NOP2 PE=1 SV=2"	"2"	"2"	"4"	"2"	"812"	"89.2"	"9.23"	"603.84"	"5.26"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf01189, Pf08062, Pf17125"	"4839"	"ENSG00000111641"	"NOP2"	"A1A4Z3; B3KPD6; hsa:4839; P46087; Q05BA7; Q0P5S5; Q3KQS4; Q58F30"	"Imatinib and chronic myeloid leukemia"	"rRNA modification in the nucleus and cytosol; TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"	"3"	"0"	"112.6"	"85.2"	"110.6"	"72.0"	"144.4"	"93.8"	"310.5"	"162.0"	"272.9"	"315.1"	"542.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UQ35"	"Serine/arginine repetitive matrix protein 2 OS=Homo sapiens OX=9606 GN=SRRM2 PE=1 SV=2"	"1"	"2"	"3"	"2"	"2752"	"299.4"	"12.06"	"420.26"	"5.25"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf08312"	"23524"	"ENSG00000167978"	"SRRM2"	"A6NKB9; D3DU97; hsa:23524; O15038; O94803; Q6NSL3; Q6PIM3; Q6PK40; Q8IW17; Q96GY7; Q9P0G1; Q9UHA8; Q9UQ35; Q9UQ36; Q9UQ37; Q9UQ38; Q9UQ40"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"17.0"	"31.0"	"37.3"	"12.2"	"39.7"	"17.6"	"246.7"	"164.3"	"182.7"	"223.1"	"327.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P29372"	"DNA-3-methyladenine glycosylase OS=Homo sapiens OX=9606 GN=MPG PE=1 SV=3"	"8"	"2"	"4"	"2"	"298"	"32.8"	"9.57"	"595.70"	"5.24"	"2"	"2"	"DNA metabolism;other metabolic processes;stress response"	"cytosol;mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf02245"	"4350"	"ENSG00000103152"	"MPG"	"G5E9E2; hsa:4350; P29372; Q13770; Q15275; Q15961; Q5J9I4; Q96BZ6; Q96S33; Q9NNX5"	"Base excision repair; DNA repair pathways, full network"	"Recognition and association of DNA glycosylase with site containing an affected purine; Cleavage of the damaged purine; Displacement of DNA glycosylase by APEX1"	"5"	"0"	"43.9"	"104.9"	"98.0"	"41.6"	"91.3"	"50.2"	"156.0"	"111.3"	"166.1"	"236.2"	"365.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P23378"	"Glycine dehydrogenase (decarboxylating), mitochondrial OS=Homo sapiens OX=9606 GN=GLDC PE=1 SV=2"	"1"	"1"	"2"	"1"	"1020"	"112.7"	"7.11"	"544.14"	"5.24"	"1"	"1"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01212, Pf02347"	"2731"	"ENSG00000178445"	"GLDC"	"hsa:2731; P23378; Q2M2F8"	""	"Glycine degradation"	"1"	"0"	"18.3"	"60.5"	"65.3"	"24.8"	"56.9"	"22.5"	"69.2"	"71.2"	"137.9"	"273.3"	"530.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P54886"	"Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2"	"3"	"2"	"4"	"2"	"795"	"87.2"	"7.12"	"584.01"	"5.24"	"2"	"2"	"other metabolic processes"	"other membranes;mitochondrion"	"kinase activity;other molecular function"	"Pf00171, Pf00696"	"5832"	"ENSG00000059573"	"ALDH18A1"	"B2R5Q4; B7Z350; B7Z5X8; B7ZLP1; D3DR44; hsa:5832; O95952; P54886; Q3KQU2; Q5T566; Q5T567; Q9UM72"	"Amino acid metabolism"	""	"1"	"0"	"42.0"	"98.8"	"97.8"	"29.3"	"87.7"	"38.4"	"62.1"	"46.4"	"73.9"	"99.5"	"163.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43290"	"U4/U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1"	"4"	"3"	"5"	"3"	"800"	"90.2"	"6.13"	"953.32"	"5.23"	"3"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	""	"Pf03343, Pf19252"	"9092"	"ENSG00000175467"	"SART1"	"A6NDN1; hsa:9092; O43290; Q53GB5"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"121.2"	"297.1"	"272.7"	"98.5"	"256.4"	"143.5"	"245.3"	"186.5"	"316.5"	"396.7"	"574.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14689"	"Disco-interacting protein 2 homolog A OS=Homo sapiens OX=9606 GN=DIP2A PE=1 SV=2"	"2"	"2"	"3"	"1"	"1571"	"170.3"	"8.03"	"266.93"	"5.23"	"1"	"2"	"cell organization and biogenesis;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;mitochondrion;other cell component"	"other molecular function"	"Pf00501, Pf06464"	"23181"	"ENSG00000160305"	"DIP2A"	"A6P4T3; B4E0F0; E7EMA5; hsa:23181; Q14689; Q8IVA3; Q8N4S2; Q8TD89; Q96ML9"	"Mesodermal commitment pathway"	""	"1"	"0"	"8.1"	"22.2"	"22.1"	"5.6"	"18.1"	"8.3"	"22.7"	"15.8"	"22.1"	"32.6"	"37.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60783"	"28S ribosomal protein S14, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS14 PE=1 SV=1"	"12"	"1"	"2"	"1"	"128"	"15.1"	"11.41"	"430.77"	"5.21"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf00253"	"63931"	"ENSG00000120333"	"MRPS14"	"hsa:63931; O60783; Q5R358"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"13.3"	"32.0"	"30.4"	"11.2"	"32.1"	"16.3"	"28.2"	"23.0"	"38.9"	"63.1"	"72.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96GC5"	"39S ribosomal protein L48, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL48 PE=1 SV=2"	"11"	"2"	"4"	"2"	"212"	"23.9"	"8.98"	"653.30"	"5.21"	"2"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	""	"Pf00338"	"51642"	"ENSG00000175581"	"MRPL48"	"B4DN34; hsa:51642; Q49AK7; Q4U2Q4; Q96GC5; Q9P091; Q9Y5J0"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"96.7"	"206.4"	"226.6"	"95.4"	"171.4"	"112.0"	"158.1"	"138.7"	"207.6"	"292.5"	"505.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9GZS1"	"DNA-directed RNA polymerase I subunit RPA49 OS=Homo sapiens OX=9606 GN=POLR1E PE=1 SV=3"	"5"	"2"	"3"	"2"	"419"	"47.2"	"8.94"	"256.67"	"5.21"	"1"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf06870"	"64425"	"ENSG00000137054"	"POLR1E"	"hsa:64425; Q5VZT3; Q8NBA9; Q96L20; Q9GZS1"	"Pyrimidine metabolism; Eukaryotic transcription initiation; 2q13 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Initiation; RNA Polymerase I Transcription Termination"	"8"	"0"	"14.6"	"62.2"	"56.6"	"19.6"	"46.5"	"23.7"	"76.1"	"95.8"	"248.3"	"640.0"	"1194.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92878"	"DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1"	"2"	"2"	"4"	"2"	"1312"	"153.8"	"6.89"	"596.72"	"5.20"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04423, Pf13476, Pf13558"	"10111"	"ENSG00000113522"	"RAD50"	"B9EGF5; hsa:10111; O43254; Q6GMT7; Q6P5X3; Q92878; Q9UP86"	"miRNA regulation of DNA damage response; Homologous recombination; DDX1 as a regulatory component of the Drosha microprocessor; ATM signaling in development and disease ; Breast cancer pathway; Joubert syndrome; DNA repair pathways, full network; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; DNA damage response"	"Sensing of DNA Double Strand Breaks; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Resolution of D-loop Structures through Holliday Junction Intermediates; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; Meiotic recombination; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; DNA Damage/Telomere Stress Induced Senescence; Nonhomologous End-Joining (NHEJ); HDR through MMEJ (alt-NHEJ)"	"29"	"0"	"8.9"	"32.0"	"25.6"	"8.0"	"23.3"	"10.3"	"34.1"	"16.9"	"41.1"	"60.9"	"119.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46060"	"Ran GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RANGAP1 PE=1 SV=1"	"3"	"2"	"3"	"2"	"587"	"63.5"	"4.68"	"401.71"	"5.19"	"1"	"2"	"protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf07834, Pf13516"	"5905"	"ENSG00000100401"	"RANGAP1"	"hsa:5905; P46060; Q96JJ2"	"22q11.2 copy number variation syndrome; IL-18 signaling pathway"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Rev-mediated nuclear export of HIV RNA; SUMOylation of DNA replication proteins; Postmitotic nuclear pore complex (NPC) reformation; SUMOylation of nuclear envelope proteins"	"12"	"0"	"31.2"	"239.4"	"136.0"	"16.8"	"118.6"	"44.9"	"37.6"	"48.1"	"46.2"	"91.6"	"170.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P26640"	"Valine--tRNA ligase OS=Homo sapiens OX=9606 GN=VARS1 PE=1 SV=4"	"1"	"2"	"4"	"2"	"1264"	"140.4"	"7.59"	"540.99"	"5.19"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol"	"other molecular function"	"Pf00043, Pf00133, Pf08264"	"7407"	"ENSG00000096171; ENSG00000204394; ENSG00000224264; ENSG00000226589; ENSG00000231116"	"VARS1"	"B0V1N1; B4DZ61; hsa:7407; P26640; Q5JQ90; Q96E77; Q9UQM2"	"Amino acid metabolism"	"Cytosolic tRNA aminoacylation"	"2"	"0"	"85.4"	"203.1"	"206.5"	"76.4"	"161.2"	"109.0"	"116.9"	"102.6"	"146.1"	"186.5"	"312.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BRA2"	"Thioredoxin domain-containing protein 17 OS=Homo sapiens OX=9606 GN=TXNDC17 PE=1 SV=1"	"15"	"2"	"3"	"2"	"123"	"13.9"	"5.52"	"344.97"	"5.18"	"1"	"2"	"signal transduction;other biological processes"	"cytosol"	"other molecular function"	"Pf06110"	"84817"	"ENSG00000129235"	"TXNDC17"	"A8K7E8; hsa:84817; Q9BRA2"	""	""	"0"	"0"	"38.6"	"349.9"	"332.7"	"26.1"	"254.9"	"78.0"	"172.8"	"87.3"	"134.6"	"163.2"	"276.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13243"	"Serine/arginine-rich splicing factor 5 OS=Homo sapiens OX=9606 GN=SRSF5 PE=1 SV=1"	"6"	"2"	"4"	"1"	"272"	"31.2"	"11.59"	"581.70"	"5.18"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00076"	"6430"	"ENSG00000100650"	"SRSF5"	"hsa:6430; O14797; Q13243; Q16662; Q49AD6; Q6FGE0"	"mRNA processing"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"6"	"0"	"46.7"	"137.3"	"168.9"	"46.7"	"154.8"	"62.4"	"169.5"	"116.9"	"189.5"	"223.4"	"363.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q02413"	"Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"1049"	"113.7"	"5.03"	"458.77"	"5.18"	"1"	"1"	"cell adhesion;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00028, Pf01049"	"1828"	"ENSG00000134760"	"DSG1"	"B7Z845; hsa:1828; Q02413"	""	"Neutrophil degranulation; Formation of the cornified envelope; RND3 GTPase cycle; Apoptotic cleavage of cell adhesion  proteins; RND2 GTPase cycle"	"6"	"0"	"12.3"	"27.3"	"95.4"	"14.3"	"17.6"	"12.7"	"24.6"	"25.0"	"35.5"	"43.6"	"39.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92572"	"AP-3 complex subunit sigma-1 OS=Homo sapiens OX=9606 GN=AP3S1 PE=1 SV=1"	"11"	"2"	"4"	"2"	"193"	"21.7"	"5.39"	"673.57"	"5.18"	"2"	"2"	"cell organization and biogenesis;transport;signal transduction"	"other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf01217"	"1176"	"ENSG00000177879"	"AP3S1"	"hsa:1176; O00647; O00676; O00721; O00727; Q53XL4; Q6ICQ2; Q92572"	""	"Golgi Associated Vesicle Biogenesis"	"1"	"0"	"66.5"	"152.3"	"156.8"	"66.0"	"147.2"	"99.1"	"228.9"	"160.3"	"221.9"	"327.6"	"487.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O96000"	"NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 OS=Homo sapiens OX=9606 GN=NDUFB10 PE=1 SV=3"	"14"	"2"	"3"	"2"	"172"	"20.8"	"8.48"	"270.21"	"5.17"	"1"	"2"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf10249"	"4716"	"ENSG00000140990"	"NDUFB10"	"hsa:4716; O96000; Q96II6"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Modulators of TCR signaling and T cell activation; Oxidative phosphorylation"	"Complex I biogenesis"	"6"	"0"	"19.2"	"118.8"	"93.0"	"21.6"	"68.7"	"36.2"	"59.3"	"46.3"	"69.3"	"94.1"	"163.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30084"	"Enoyl-CoA hydratase, mitochondrial OS=Homo sapiens OX=9606 GN=ECHS1 PE=1 SV=4"	"6"	"1"	"2"	"1"	"290"	"31.4"	"8.07"	"528.28"	"5.17"	"1"	"1"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00378"	"1892"	"ENSG00000127884"	"ECHS1"	"hsa:1892; O00739; P30084; Q5VWY1; Q96H54"	"Fatty acid beta-oxidation; Fatty acid biosynthesis; Ciliary landscape; Tryptophan metabolism"	"Branched-chain amino acid catabolism; Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA; Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of butanoyl-CoA to acetyl-CoA; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA"	"10"	"0"	"3.6"	"30.8"	"44.3"	"6.6"	"31.2"	"9.6"	"62.9"	"47.4"	"53.2"	"51.0"	"125.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96AC1"	"Fermitin family homolog 2 OS=Homo sapiens OX=9606 GN=FERMT2 PE=1 SV=1"	"5"	"2"	"4"	"2"	"680"	"77.8"	"6.70"	"315.00"	"5.17"	"1"	"2"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00169, Pf00373, Pf18124"	"10979"	"ENSG00000073712"	"FERMT2"	"B5TJY2; hsa:10979; Q14840; Q86TY7; Q96AC1"	""	"RAC1 GTPase cycle; RAC3 GTPase cycle; Cell-extracellular matrix interactions"	"3"	"0"	"10.3"	"31.9"	"28.7"	"12.1"	"28.8"	"12.1"	"18.2"	"25.2"	"31.2"	"42.8"	"60.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82921"	"28S ribosomal protein S21, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS21 PE=1 SV=3"	"14"	"1"	"3"	"1"	"87"	"10.7"	"9.92"	"326.46"	"5.15"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf01165"	"54460"	"ENSG00000266472"	"MRPS21"	"A0A075B746; hsa:54460; P82921; Q5TB11; Q9BST6"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"26.0"	"68.6"	"65.6"	"23.5"	"65.7"	"33.5"	"42.6"	"31.7"	"50.7"	"73.1"	"95.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WUM4"	"Programmed cell death 6-interacting protein OS=Homo sapiens OX=9606 GN=PDCD6IP PE=1 SV=1"	"1"	"1"	"4"	"1"	"868"	"96.0"	"6.52"	"825.57"	"5.15"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"non-structural extracellular;plasma membrane;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf03097, Pf13949"	"10015"	"ENSG00000170248"	"PDCD6IP"	"C5MQH7; E9PFU1; hsa:10015; Q6NUS1; Q8WUM4; Q9BX86; Q9NUN0; Q9P2H2; Q9UKL5"	"Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells"	"Budding and maturation of HIV virion; Regulation of necroptotic cell death; Uptake and function of anthrax toxins"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P56381"	"ATP synthase subunit epsilon, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1E PE=1 SV=2"	"29"	"2"	"4"	"2"	"51"	"5.8"	"9.92"	"581.72"	"5.14"	"2"	"2"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf04627"	"514"	"ENSG00000124172"	"ATP5F1E"	"B2RDD0; E1P5H6; hsa:514; P56381; Q53XU6"	"Electron transport chain: OXPHOS system in mitochondria; 7q11.23 copy number variation syndrome; Oxidative phosphorylation"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"5"	"0"	"161.6"	"434.5"	"447.5"	"116.3"	"372.0"	"138.1"	"372.1"	"318.8"	"418.1"	"510.2"	"887.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H0W8"	"Protein SMG9 OS=Homo sapiens OX=9606 GN=SMG9 PE=1 SV=1"	"3"	"1"	"2"	"1"	"520"	"57.6"	"7.01"	"528.01"	"5.14"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes"	"cytosol"	"other molecular function"	"Pf10220"	"56006"	"ENSG00000105771"	"SMG9"	"hsa:56006; O60429; Q9H0W8; Q9H9A9"	""	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	"1"	"0"	"22.4"	"32.0"	"28.8"	"18.5"	"35.4"	"24.4"	"45.4"	"35.0"	"43.1"	"61.7"	"81.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IXI1"	"Mitochondrial Rho GTPase 2 OS=Homo sapiens OX=9606 GN=RHOT2 PE=1 SV=2"	"4"	"2"	"4"	"2"	"618"	"68.1"	"5.86"	"696.63"	"5.13"	"2"	"2"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf00071, Pf08355, Pf08356"	"89941"	"ENSG00000140983"	"RHOT2"	"A2IDC2; hsa:89941; Q8IXI1; Q8NF53; Q96C13; Q96S17; Q9BT60; Q9H7M8"	""	"RHOT2 GTPase cycle"	"1"	"0"	"13.9"	"35.2"	"31.4"	"5.2"	"27.5"	"9.3"	"17.1"	"14.1"	"19.8"	"24.1"	"41.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UNM6"	"26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2"	"5"	"2"	"2"	"2"	"376"	"42.9"	"5.81"	""	"5.12"	""	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf01399"	"5719"	"ENSG00000185627"	"PSMD13"	"B3KT15; hsa:5719; O75831; Q53XU2; Q9UNM6; Q9UNV3"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Ciliary landscape; Alzheimer's disease"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"65"	"0"	"124.8"	"289.7"	"280.0"	"104.6"	"271.5"	"147.2"	"159.4"	"129.6"	"197.4"	"260.6"	"395.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BTL3"	"RNA guanine-N7 methyltransferase activating subunit OS=Homo sapiens OX=9606 GN=RAMAC PE=1 SV=1"	"13"	"1"	"2"	"1"	"118"	"14.4"	"8.94"	"708.49"	"5.12"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf15320"	"83640"	"ENSG00000169612"	"RAMAC"	"hsa:83640; Q2M1J8; Q9BTL3"	""	""	"0"	"0"	"22.5"	"44.6"	"40.6"	"23.6"	"43.1"	"25.6"	"48.4"	"38.7"	"61.8"	"61.7"	"68.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H0S4"	"Probable ATP-dependent RNA helicase DDX47 OS=Homo sapiens OX=9606 GN=DDX47 PE=1 SV=1"	"7"	"2"	"4"	"2"	"455"	"50.6"	"9.10"	"618.93"	"5.12"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;signal transduction"	"nucleus"	"other molecular function"	"Pf00270, Pf00271"	"51202"	"ENSG00000213782"	"DDX47"	"B3KXP4; G5E955; hsa:51202; Q96GM0; Q96NV8; Q9H0S4; Q9UI98"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"3.9"	"16.0"	"18.6"	"5.0"	"14.4"	"6.2"	"21.3"	"16.2"	"25.9"	"33.4"	"45.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NZL9"	"Methionine adenosyltransferase 2 subunit beta OS=Homo sapiens OX=9606 GN=MAT2B PE=1 SV=1"	"4"	"1"	"4"	"1"	"334"	"37.5"	"7.36"	"814.99"	"5.12"	"1"	"1"	"other metabolic processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf04321"	"27430"	"ENSG00000038274"	"MAT2B"	"B2R5Y6; hsa:27430; Q1WAI7; Q27J92; Q3LIE8; Q567T7; Q6NYC7; Q9BS89; Q9H3E1; Q9NZL9; Q9UJ54"	"Trans-sulfuration pathway; One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways; Methionine de novo and salvage pathway; Methylation pathways"	"Ub-specific processing proteases; Methylation"	"7"	"0"	"91.3"	"320.0"	"267.7"	"70.1"	"244.2"	"107.7"	"153.0"	"120.1"	"157.3"	"177.0"	"303.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NR12"	"PDZ and LIM domain protein 7 OS=Homo sapiens OX=9606 GN=PDLIM7 PE=1 SV=1"	"6"	"3"	"5"	"3"	"457"	"49.8"	"8.41"	"775.91"	"5.12"	"3"	"2"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412, Pf00595"	"9260"	"ENSG00000196923"	"PDLIM7"	"hsa:9260; Q14250; Q5XG82; Q6NVZ5; Q96C91; Q9BXB8; Q9BXB9; Q9NR12"	"Ebstein-Barr virus LMP1 signaling; GDNF signaling"	"RET signaling"	"3"	"0"	"181.7"	"306.4"	"272.4"	"119.1"	"250.4"	"149.7"	"252.2"	"197.4"	"257.0"	"349.1"	"556.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BWD1"	"Acetyl-CoA acetyltransferase, cytosolic OS=Homo sapiens OX=9606 GN=ACAT2 PE=1 SV=2"	"6"	"3"	"4"	"3"	"397"	"41.3"	"6.92"	"541.39"	"5.11"	"2"	"2"	"other metabolic processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00108, Pf02803"	"39"	"ENSG00000120437"	"ACAT2"	"B7Z233; E1P5B1; hsa:39; Q16146; Q5TCL7; Q8TDM4; Q9BWD1"	"Mevalonate pathway; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Cholesterol metabolism; Cholesterol biosynthesis pathway in hepatocytes; Enterocyte cholesterol metabolism"	"Cholesterol biosynthesis"	"6"	"0"	"56.0"	"433.5"	"346.2"	"42.5"	"270.9"	"81.2"	"129.7"	"104.9"	"128.1"	"176.0"	"414.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5V0"	"Zinc finger protein 706 OS=Homo sapiens OX=9606 GN=ZNF706 PE=1 SV=1"	"24"	"2"	"3"	"2"	"76"	"8.5"	"10.01"	"246.51"	"5.10"	"1"	"2"	"other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf04419, Pf12874"	"51123"	"ENSG00000120963"	"ZNF706"	"A8K362; hsa:51123; Q9Y5V0"	""	"Generic Transcription Pathway"	"1"	"0"	"194.3"	"209.2"	"251.2"	"145.6"	"262.7"	"167.9"	"456.6"	"323.1"	"575.6"	"740.3"	"1325.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A3KMH1"	"von Willebrand factor A domain-containing protein 8 OS=Homo sapiens OX=9606 GN=VWA8 PE=1 SV=2"	"1"	"2"	"4"	"2"	"1905"	"214.7"	"7.40"	"589.48"	"5.09"	"2"	"2"	""	"mitochondrion;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf07728"	"23078"	"ENSG00000102763"	"VWA8"	"A3KMH1; hsa:23078; O60310; Q5JTP6; Q5VW08; Q7Z6I9; Q86YC9; Q8N3E4"	""	""	"0"	"0"	"20.7"	"50.2"	"62.7"	"24.9"	"54.8"	"22.9"	"72.7"	"55.0"	"97.6"	"107.4"	"173.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75874"	"Isocitrate dehydrogenase [NADP] cytoplasmic OS=Homo sapiens OX=9606 GN=IDH1 PE=1 SV=2"	"4"	"2"	"4"	"2"	"414"	"46.6"	"7.01"	"561.04"	"5.09"	"2"	"2"	"other metabolic processes;stress response;developmental processes;other biological processes"	"non-structural extracellular;cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00180"	"3417"	"ENSG00000138413"	"IDH1"	"hsa:3417; O75874; Q567U4; Q6FHQ6; Q7Z3V0; Q93090; Q9NTJ9; Q9UKW8"	"Glutathione metabolism; TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism"	"Peroxisomal protein import; Neutrophil degranulation; Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate; NADPH regeneration; NFE2L2 regulating TCA cycle genes"	"8"	"0"	"28.4"	"325.2"	"222.0"	"7.1"	"153.4"	"39.8"	"52.1"	"50.1"	"60.7"	"83.0"	"186.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96HS1"	"Serine/threonine-protein phosphatase PGAM5, mitochondrial OS=Homo sapiens OX=9606 GN=PGAM5 PE=1 SV=2"	"6"	"2"	"4"	"2"	"289"	"32.0"	"8.68"	"585.67"	"5.08"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion"	"enzyme regulator activity;other molecular function"	"Pf00300"	"192111"	"ENSG00000247077"	"PGAM5"	"A9LN06; C9IZY7; hsa:192111; Q96HS1; Q96JB0"	"NRF2-ARE regulation"	""	"1"	"0"	"93.7"	"401.6"	"329.8"	"94.7"	"256.6"	"117.2"	"199.5"	"209.0"	"272.1"	"404.5"	"705.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62805"	"Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2"	"19"	"2"	"4"	"2"	"103"	"11.4"	"11.36"	"590.87"	"5.08"	"2"	"2"	"cell organization and biogenesis;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf15511"	"121504; 554313; 8294; 8359; 8360; 8361; 8362; 8363; 8364; 8365; 8366; 8367; 8368; 8370"	"ENSG00000158406; ENSG00000197061; ENSG00000197238; ENSG00000197837; ENSG00000270276; ENSG00000270882; ENSG00000273542; ENSG00000274618; ENSG00000275126; ENSG00000276180; ENSG00000276966; ENSG00000277157; ENSG00000278637; ENSG00000278705"	"H4C1; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9"	"A2VCL0; hsa:121504; hsa:554313; hsa:8294; hsa:8359; hsa:8360; hsa:8361; hsa:8362; hsa:8363; hsa:8364; hsa:8365; hsa:8366; hsa:8367; hsa:8368; hsa:8370; P02304; P02305; P62805; Q6DRA9; Q6FGB8; Q6NWP7"	"Gastric cancer network 1; Histone modifications; 22q11.2 copy number variation syndrome; Male infertility; 11p11.2 copy number variation syndrome ; Type II interferon signaling"	"Meiotic synapsis; Estrogen-dependent gene expression; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; Meiotic recombination; SUMOylation of chromatin organization proteins; HCMV Late Events; Amyloid fiber formation; RUNX1 regulates transcription of genes involved in differentiation of HSCs; HCMV Early Events; Transcriptional regulation by small RNAs; Deposition of new CENPA-containing nucleosomes at the centromere; B-WICH complex positively regulates rRNA expression; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Formation of the beta-catenin:TCF transactivating complex; Oxidative Stress Induced Senescence; HDACs deacetylate histones; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Pre-NOTCH Transcription and Translation; Senescence-Associated Secretory Phenotype (SASP); RMTs methylate histone arginines; HDMs demethylate histones; PKMTs methylate histone lysines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; HATs acetylate histones; RNA Polymerase I Promoter Escape; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Packaging Of Telomere Ends; Condensation of Prophase Chromosomes; DNA Damage/Telomere Stress Induced Senescence; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; Nonhomologous End-Joining (NHEJ); RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis"	"51"	"0"	"49.6"	"198.4"	"205.3"	"47.1"	"140.6"	"58.3"	"102.0"	"87.2"	"126.1"	"168.4"	"242.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N7H5"	"RNA polymerase II-associated factor 1 homolog OS=Homo sapiens OX=9606 GN=PAF1 PE=1 SV=2"	"3"	"2"	"4"	"2"	"531"	"59.9"	"4.63"	"554.43"	"5.07"	"2"	"2"	"cell-cell signaling;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf03985"	"54623"	"ENSG00000006712"	"PAF1"	"hsa:54623; M0QX35; O75239; Q8N7H5; Q9H166; Q9NUU9"	"Endoderm differentiation"	"E3 ubiquitin ligases ubiquitinate target proteins; Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events"	"5"	"0"	"154.0"	"140.7"	"215.4"	"145.5"	"237.6"	"202.9"	"349.9"	"244.2"	"363.9"	"347.8"	"439.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WXC6"	"COP9 signalosome complex subunit 9 OS=Homo sapiens OX=9606 GN=COPS9 PE=1 SV=3"	"35"	"1"	"2"	"1"	"57"	"6.2"	"3.83"	"463.93"	"5.07"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	""	"Pf15004"	"150678"	"ENSG00000172428"	"COPS9"	"hsa:150678; Q8N110; Q8WXC6"	"2q37 copy number variation syndrome"	""	"1"	"0"	"7.6"	"13.2"	"14.2"	"6.4"	"13.4"	"6.9"	"13.8"	"12.6"	"13.2"	"22.7"	"23.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75940"	"Survival of motor neuron-related-splicing factor 30 OS=Homo sapiens OX=9606 GN=SMNDC1 PE=1 SV=1"	"13"	"3"	"5"	"3"	"238"	"26.7"	"7.24"	"953.05"	"5.06"	"3"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf06003"	"10285"	"ENSG00000119953"	"SMNDC1"	"B2RA27; D3DRB1; hsa:10285; O75940; Q5T3K6"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"163.8"	"250.2"	"274.1"	"140.8"	"248.5"	"144.6"	"443.8"	"288.5"	"502.8"	"581.0"	"770.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05556"	"Integrin beta-1 OS=Homo sapiens OX=9606 GN=ITGB1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"798"	"88.4"	"5.39"	"523.22"	"5.06"	"1"	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00362, Pf07965, Pf07974, Pf08725, Pf17205, Pf18372"	"3688"	"ENSG00000150093"	"ITGB1"	"A8K6N2; D3DRX9; D3DRY3; D3DRY4; D3DRY5; hsa:3688; P05556; P78466; P78467; Q13089; Q13090; Q13091; Q13212; Q14622; Q14647; Q29RW2; Q7Z3V1; Q8WUM6"	"Integrin-mediated cell adhesion; Prolactin signaling pathway; Neural crest differentiation; Arrhythmogenic right ventricular cardiomyopathy; Pathogenic Escherichia coli infection; Primary focal segmental glomerulosclerosis (FSGS); Mammary gland development pathway - Embryonic development (Stage 1 of 4); Focal adhesion; Hepatocyte growth factor receptor signaling; RAC1/PAK1/p38/MMP2 pathway; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; VEGFA-VEGFR2 signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Ebola virus infection in host; Cells and molecules involved in local acute inflammatory response ; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Small cell lung cancer; Gastrin signaling pathway; Genes controlling nephrogenesis; Development of ureteric collection system; Pleural mesothelioma; CCL18 signaling pathway; GDNF signaling; TROP2 regulatory signaling; 11p11.2 copy number variation syndrome ; A network map of Macrophage-stimulating protein (MSP) signaling"	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell; Potential therapeutics for SARS; RAC1 GTPase cycle; RHOG GTPase cycle; RHO GTPases Activate Formins; HCMV Early Events; RAC2 GTPase cycle; RAC3 GTPase cycle; Integrin cell surface interactions; ECM proteoglycans; GPER1 signaling; CHL1 interactions; Interleukin-4 and Interleukin-13 signaling; Signal transduction by L1; Syndecan interactions; Other semaphorin interactions; Laminin interactions; MET activates PTK2 signaling; Basigin interactions; Platelet Adhesion to exposed collagen; Molecules associated with elastic fibres; TGF-beta receptor signaling activates SMADs; Fibronectin matrix formation; Localization of the PINCH-ILK-PARVIN complex to focal adhesions; MET interacts with TNS proteins"	"54"	"0"	"21.8"	"56.7"	"41.9"	"15.8"	"47.8"	"19.1"	"35.2"	"27.2"	"45.9"	"65.4"	"104.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P78346"	"Ribonuclease P protein subunit p30 OS=Homo sapiens OX=9606 GN=RPP30 PE=1 SV=1"	"9"	"2"	"3"	"2"	"268"	"29.3"	"8.91"	"276.94"	"5.06"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01876"	"10556"	"ENSG00000148688"	"RPP30"	"B2R799; E9PB02; hsa:10556; P78346"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; tRNA processing in the nucleus"	"2"	"0"	"13.3"	"42.6"	"42.1"	"11.3"	"31.4"	"14.7"	"35.6"	"27.0"	"34.4"	"57.3"	"84.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UJU6"	"Drebrin-like protein OS=Homo sapiens OX=9606 GN=DBNL PE=1 SV=1"	"5"	"1"	"2"	"1"	"430"	"48.2"	"5.05"	"493.62"	"5.06"	"1"	"1"	"cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00241, Pf14604"	"28988"	"ENSG00000136279"	"DBNL"	"A4D2I9; B4DDP6; B4DEM2; C9J7P1; hsa:28988; P84070; Q6IAI8; Q96F30; Q96K74; Q9HBN8; Q9NR72; Q9UJU6"	"T-cell receptor signaling pathway"	"Neutrophil degranulation; Neurexins and neuroligins; Caspase-mediated cleavage of cytoskeletal proteins"	"4"	"0"	"18.7"	"78.3"	"82.2"	"21.8"	"74.6"	"31.5"	"56.8"	"41.8"	"57.5"	"72.9"	"112.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12972"	"Nuclear inhibitor of protein phosphatase 1 OS=Homo sapiens OX=9606 GN=PPP1R8 PE=1 SV=2"	"6"	"1"	"1"	"1"	"351"	"38.5"	"7.37"	""	"5.05"	""	"1"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00498"	"5511"	"ENSG00000117751"	"PPP1R8"	"hsa:5511; Q12972; Q5TEJ2; Q5TEJ4; Q5TIF2; Q6PKF6; Q9UBH1; Q9UBZ0"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"15.4"	"33.9"	"38.1"	"18.1"	"27.1"	"14.6"	"22.3"	"20.4"	"26.6"	"30.6"	"47.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13330"	"Metastasis-associated protein MTA1 OS=Homo sapiens OX=9606 GN=MTA1 PE=1 SV=2"	"4"	"2"	"4"	"2"	"715"	"80.7"	"9.26"	"554.63"	"5.05"	"2"	"2"	"cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00249, Pf00320, Pf01426, Pf01448, Pf17226"	"9112"	"ENSG00000182979"	"MTA1"	"A5PLK4; hsa:9112; Q13330; Q86SW2; Q8NFI8; Q96GI8"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"Potential therapeutics for SARS; Regulation of PTEN gene transcription; HDACs deacetylate histones; RNA Polymerase I Transcription Initiation; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; SUMOylation of transcription factors"	"7"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94905"	"Erlin-2 OS=Homo sapiens OX=9606 GN=ERLIN2 PE=1 SV=1"	"5"	"2"	"3"	"2"	"339"	"37.8"	"5.62"	"311.71"	"5.04"	"1"	"2"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf01145"	"11160"	"ENSG00000147475"	"ERLIN2"	"A0JLQ1; A8K5S9; B4DM38; D3DSW0; hsa:11160; O94905; Q6NW21; Q86VS6; Q86W49"	""	"ABC-family proteins mediated transport; Defective CFTR causes cystic fibrosis; Signaling by FGFR1 in disease; Signaling by plasma membrane FGFR1 fusions"	"4"	"0"	"109.7"	"337.2"	"307.3"	"100.6"	"233.8"	"126.9"	"120.6"	"105.3"	"151.6"	"252.0"	"414.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NX24"	"H/ACA ribonucleoprotein complex subunit 2 OS=Homo sapiens OX=9606 GN=NHP2 PE=1 SV=1"	"12"	"1"	"2"	"1"	"153"	"17.2"	"8.22"	"611.04"	"4.99"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf01248"	"55651"	"ENSG00000145912"	"NHP2"	"A6NKY8; hsa:55651; Q9NX24; Q9P095"	""	"rRNA modification in the nucleus and cytosol; Telomere Extension By Telomerase"	"2"	"0"	"13.5"	"25.6"	"27.2"	"11.6"	"34.7"	"18.1"	"43.4"	"39.6"	"95.8"	"152.4"	"207.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P53985"	"Monocarboxylate transporter 1 OS=Homo sapiens OX=9606 GN=SLC16A1 PE=1 SV=3"	"4"	"1"	"2"	"1"	"500"	"53.9"	"8.66"	"652.47"	"4.97"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"transporter activity;other molecular function"	"Pf07690"	"6566"	"ENSG00000155380; ENSG00000281917"	"SLC16A1"	"hsa:6566; P53985; Q49A45; Q5T8R6; Q9NSJ9"	"Photodynamic therapy-induced HIF-1 survival signaling; Fragile X syndrome; Glucose metabolism in triple-negative breast cancer cells"	"Basigin interactions; Pyruvate metabolism; Aspirin ADME; Proton-coupled monocarboxylate transport; Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT)"	"8"	"0"	"69.3"	"124.5"	"150.1"	"67.7"	"141.8"	"76.9"	"127.1"	"81.9"	"141.8"	"173.1"	"240.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96KP4"	"Cytosolic non-specific dipeptidase OS=Homo sapiens OX=9606 GN=CNDP2 PE=1 SV=2"	"4"	"1"	"2"	"1"	"475"	"52.8"	"5.97"	"729.72"	"4.96"	"1"	"1"	"protein metabolism"	"cytosol;nucleus"	"other molecular function"	"Pf01546, Pf07687"	"55748"	"ENSG00000133313"	"CNDP2"	"B3KUG4; hsa:55748; Q8WY59; Q96KP4; Q9BQ94; Q9NVB4; V9HWE5"	""	"Glutathione synthesis and recycling; Paracetamol ADME"	"2"	"0"	"8.4"	"51.6"	"44.3"	"4.3"	"36.3"	"9.7"	"13.5"	"4.2"	"16.2"	"15.7"	"40.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BRX8"	"Peroxiredoxin-like 2A OS=Homo sapiens OX=9606 GN=PRXL2A PE=1 SV=3"	"5"	"1"	"4"	"1"	"229"	"25.7"	"8.84"	"550.32"	"4.96"	"1"	"1"	"other biological processes"	"non-structural extracellular;other cell component"	"other molecular function"	"Pf13911"	"84293"	"ENSG00000122378"	"PRXL2A"	"B2RD81; hsa:84293; Q6UW08; Q8N2K3; Q8NBK9; Q96JR0; Q9BRX8"	""	""	"0"	"0"	"5.5"	"21.2"	"24.1"	"6.2"	"18.7"	"9.0"	"9.1"	"8.6"	"20.9"	"31.5"	"36.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5D862"	"Filaggrin-2 OS=Homo sapiens OX=9606 GN=FLG2 PE=1 SV=1"	"2"	"2"	"2"	"2"	"2391"	"247.9"	"8.31"	""	"4.96"	""	"2"	"cell adhesion;other biological processes"	"non-structural extracellular;plasma membrane;other cell component"	"other molecular function"	"Pf01023"	"388698"	"ENSG00000143520"	"FLG2"	"hsa:388698; Q5D862; Q9H4U1"	""	"Neutrophil degranulation"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31153"	"S-adenosylmethionine synthase isoform type-2 OS=Homo sapiens OX=9606 GN=MAT2A PE=1 SV=1"	"2"	"1"	"4"	"1"	"395"	"43.6"	"6.48"	"530.59"	"4.95"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00438, Pf02772, Pf02773"	"4144"	"ENSG00000168906"	"MAT2A"	"A8K511; B4DN45; D6W5L1; hsa:4144; P31153; Q53SP5"	"Trans-sulfuration, one-carbon metabolism and related pathways; Methionine de novo and salvage pathway; Methylation pathways"	"Methylation"	"4"	"0"	"201.3"	"830.7"	"688.5"	"145.2"	"627.9"	"220.8"	"328.6"	"310.1"	"363.7"	"400.4"	"800.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NVM6"	"DnaJ homolog subfamily C member 17 OS=Homo sapiens OX=9606 GN=DNAJC17 PE=1 SV=1"	"10"	"2"	"3"	"2"	"304"	"34.7"	"8.53"	"729.37"	"4.94"	"2"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf00226"	"55192"	"ENSG00000104129"	"DNAJC17"	"hsa:55192; Q9NVM6"	""	""	"0"	"0"	"2.6"	"4.2"	"6.2"	"2.0"	"4.4"	"3.5"	"7.3"	"7.6"	"21.0"	"36.9"	"103.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z460"	"CLIP-associating protein 1 OS=Homo sapiens OX=9606 GN=CLASP1 PE=1 SV=1"	"1"	"2"	"4"	"1"	"1538"	"169.3"	"9.03"	"534.27"	"4.94"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02985, Pf12348"	"23332"	"ENSG00000074054"	"CLASP1"	"A2RU21; B7ZLX3; F5GWS0; hsa:23332; O75118; Q2KHQ9; Q5H9P0; Q7Z460; Q8N5B8; Q9BQT5"	"Microtubule cytoskeleton regulation; Splicing factor NOVA regulated synaptic proteins; 7q11.23 copy number variation syndrome"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Role of ABL in ROBO-SLIT signaling"	"17"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IWF6"	"Protein DENND6A OS=Homo sapiens OX=9606 GN=DENND6A PE=1 SV=1"	"2"	"1"	"2"	"1"	"608"	"69.5"	"8.27"	"552.42"	"4.94"	"1"	"1"	"other biological processes"	"cytosol;other cytoplasmic organelle;other cell component"	"enzyme regulator activity"	"Pf08616, Pf09794"	"201627"	"ENSG00000174839"	"DENND6A"	"hsa:201627; Q7Z5T4; Q8IWF6; Q8N235; Q8TEG8"	""	"RAB GEFs exchange GTP for GDP on RABs"	"1"	"0"	"9.2"	"21.0"	"18.2"	"5.9"	"13.6"	"4.3"	"18.9"	"13.3"	"21.4"	"32.8"	"56.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55786"	"Puromycin-sensitive aminopeptidase OS=Homo sapiens OX=9606 GN=NPEPPS PE=1 SV=2"	"2"	"2"	"4"	"2"	"919"	"103.2"	"5.72"	"628.33"	"4.94"	"2"	"2"	"protein metabolism;other metabolic processes;stress response"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01433, Pf11838, Pf17900"	"9520"	"ENSG00000141279"	"NPEPPS"	"B7Z463; hsa:9520; P55786; Q6P145; Q9NP16; Q9UEM2"	""	"Antigen processing: Ubiquitination & Proteasome degradation"	"1"	"0"	"33.1"	"160.6"	"142.8"	"25.9"	"129.1"	"41.6"	"72.2"	"54.9"	"84.6"	"130.3"	"214.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96GQ7"	"Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2"	"6"	"4"	"7"	"4"	"796"	"89.8"	"9.28"	"1060.49"	"4.93"	"4"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271"	"55661"	""	"DDX27"	"A0AVB6; B7ZLY1; hsa:55661; Q5VXM7; Q8WYG4; Q969N7; Q96F57; Q96GQ7; Q96L97; Q9BWY9; Q9BXF0; Q9H990; Q9NWU3; Q9P0C2; Q9UGD6"	""	""	"0"	"0"	"12.8"	"24.0"	"30.9"	"7.4"	"23.2"	"13.8"	"22.3"	"16.8"	"21.9"	"33.5"	"49.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q641Q2"	"WASH complex subunit 2A OS=Homo sapiens OX=9606 GN=WASHC2A PE=1 SV=3"	"3"	"2"	"2"	"2"	"1341"	"147.1"	"4.81"	""	"4.93"	""	"2"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf15255"	"387680"	"ENSG00000099290"	"WASHC2A"	"A2A3S2; A2A3U6; hsa:387680; Q5SNT6; Q641Q2; Q6DHY0"	"10q11.21q11.23 copy number variation syndrome"	""	"1"	"0"	"8.5"	"13.6"	"10.9"	"5.1"	"13.6"	"7.5"	"10.4"	"9.2"	"10.5"	"15.1"	"20.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82914"	"28S ribosomal protein S15, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS15 PE=1 SV=1"	"7"	"2"	"3"	"2"	"257"	"29.8"	"10.48"	"271.80"	"4.93"	"1"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf00312"	"64960"	"ENSG00000116898"	"MRPS15"	"B2RD82; hsa:64960; P82914; Q9H2K1"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"123.2"	"332.1"	"295.9"	"127.3"	"275.4"	"138.7"	"190.8"	"165.0"	"233.5"	"325.6"	"567.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31944"	"Caspase-14 OS=Homo sapiens OX=9606 GN=CASP14 PE=1 SV=2"	"10"	"2"	"4"	"2"	"242"	"27.7"	"5.58"	"706.08"	"4.92"	"2"	"2"	"protein metabolism;other biological processes"	"plasma membrane;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00656"	"23581"	"ENSG00000105141"	"CASP14"	"hsa:23581; O95823; P31944; Q3SYC9"	"Vitamin D receptor pathway"	"Formation of the cornified envelope"	"2"	"0"	"16.3"	"42.4"	"52.2"	"14.4"	"39.9"	"23.2"	"57.0"	"53.4"	"64.9"	"96.4"	"118.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19367"	"Hexokinase-1 OS=Homo sapiens OX=9606 GN=HK1 PE=1 SV=3"	"2"	"2"	"4"	"2"	"917"	"102.4"	"6.80"	"527.54"	"4.91"	"2"	"2"	"other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;mitochondrion"	"kinase activity;other molecular function"	"Pf00349, Pf03727"	"3098"	"ENSG00000156515"	"HK1"	"E9PCK0; hsa:3098; O43443; O43444; O75574; P19367; Q5VTC3; Q96HC8; Q9NNZ4; Q9NNZ5"	"Cori cycle; Photodynamic therapy-induced HIF-1 survival signaling; Clear cell renal cell carcinoma pathways; Aerobic glycolysis; Disorders of fructose metabolism; Glucose metabolism in triple-negative breast cancer cells; Glycolysis and gluconeogenesis; UDP-derived sugars synthesis in fibroblasts; Glucuronidation"	"Glycolysis; Defective HK1 causes hexokinase deficiency (HK deficiency)"	"11"	"0"	"11.5"	"26.4"	"22.3"	"9.2"	"14.2"	"11.7"	"20.2"	"13.0"	"18.3"	"19.2"	"29.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P17858"	"ATP-dependent 6-phosphofructokinase, liver type OS=Homo sapiens OX=9606 GN=PFKL PE=1 SV=6"	"1"	"1"	"2"	"1"	"780"	"85.0"	"7.50"	"377.06"	"4.91"	"1"	"1"	"other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00365"	"5211"	"ENSG00000141959"	"PFKL"	"hsa:5211; P17858; Q96A64; Q96IH4; Q9BR91"	"Photodynamic therapy-induced HIF-1 survival signaling; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Insulin signaling; Disorders of fructose metabolism; Glycolysis and gluconeogenesis"	"Neutrophil degranulation; Glycolysis"	"8"	"0"	"40.0"	"132.9"	"104.0"	"21.2"	"96.6"	"37.2"	"49.2"	"46.2"	"63.2"	"87.7"	"151.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N9N8"	"Probable RNA-binding protein EIF1AD OS=Homo sapiens OX=9606 GN=EIF1AD PE=1 SV=1"	"10"	"1"	"2"	"1"	"165"	"19.0"	"5.21"	"409.37"	"4.91"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01176"	"84285"	"ENSG00000175376"	"EIF1AD"	"B2R4N5; hsa:84285; Q8N9N8; Q9BSC1"	""	""	"0"	"0"	"24.0"	"26.4"	"31.3"	"13.9"	"28.8"	"20.9"	"26.1"	"28.7"	"31.8"	"30.8"	"45.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P20585"	"DNA mismatch repair protein Msh3 OS=Homo sapiens OX=9606 GN=MSH3 PE=1 SV=4"	"4"	"3"	"4"	"3"	"1137"	"127.3"	"8.02"	"654.77"	"4.90"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00488, Pf01624, Pf05188, Pf05192"	"4437"	"ENSG00000113318"	"MSH3"	"A1L480; A1L482; A6NMM6; hsa:4437; P20585; Q6PJT5; Q86UQ6; Q92867"	"Chromosomal and microsatellite instability in colorectal cancer ; DNA repair pathways, full network"	"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta); Defective Mismatch Repair Associated With MSH3; Defective Mismatch Repair Associated With MSH2"	"5"	"0"	"19.3"	"39.6"	"31.9"	"19.3"	"35.5"	"14.4"	"40.4"	"27.1"	"35.6"	"51.1"	"80.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P0CG12"	"Decreased expression in renal and prostate cancer protein OS=Homo sapiens OX=9606 GN=DERPC PE=1 SV=1"	"5"	"2"	"3"	"2"	"524"	"51.4"	"12.41"	"329.54"	"4.89"	"1"	"2"	""	"nucleus"	""	""	""	"ENSG00000286140"	"DERPC"	"A8MYX8; P0CG12; Q71E72; Q8NDH8; Q8WV66; Q9NX73"	""	""	"0"	"0"	"16.5"	"21.1"	"21.6"	"15.2"	"30.2"	"21.8"	"29.8"	"35.2"	"40.8"	"50.4"	"65.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BRL6"	"Serine/arginine-rich splicing factor 8 OS=Homo sapiens OX=9606 GN=SRSF8 PE=1 SV=1"	"5"	"2"	"4"	"2"	"282"	"32.3"	"11.72"	"503.69"	"4.89"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	""	"Pf00076"	"10929"	"ENSG00000263465"	"SRSF8"	"B2R6B8; hsa:10929; Q6PF01; Q96TA3; Q9BRL6"	""	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"2"	"0"	"203.5"	"537.1"	"526.9"	"173.1"	"520.5"	"224.2"	"620.5"	"396.4"	"525.3"	"681.1"	"1147.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IY63"	"Angiomotin-like protein 1 OS=Homo sapiens OX=9606 GN=AMOTL1 PE=1 SV=1"	"2"	"2"	"2"	"1"	"956"	"106.5"	"7.11"	""	"4.88"	""	"2"	"cell-cell signaling;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf12240"	"154810"	"ENSG00000166025"	"AMOTL1"	"hsa:154810; Q63HK7; Q8IY63; Q8NDN0; Q8TEN8; Q8WXD1; Q96CM5"	""	"Signaling by Hippo"	"1"	"0"	"5.1"	"9.4"	"13.8"	"8.6"	"10.8"	"6.0"	"11.9"	"10.9"	"19.8"	"24.0"	"30.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NI27"	"THO complex subunit 2 OS=Homo sapiens OX=9606 GN=THOC2 PE=1 SV=2"	"1"	"2"	"4"	"2"	"1593"	"182.7"	"8.44"	"643.69"	"4.88"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf11262, Pf11732, Pf16134"	"57187"	"ENSG00000125676"	"THOC2"	"A6NM50; hsa:57187; Q5JZ12; Q6IN92; Q8NI27; Q9H8I6"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"3"	"0"	"182.4"	"261.1"	"295.2"	"134.1"	"293.0"	"182.6"	"498.6"	"298.0"	"483.8"	"584.4"	"823.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61758"	"Prefoldin subunit 3 OS=Homo sapiens OX=9606 GN=VBP1 PE=1 SV=4"	"9"	"2"	"4"	"2"	"197"	"22.6"	"7.11"	"545.62"	"4.87"	"2"	"2"	"cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02996"	"7411"	"ENSG00000155959"	"VBP1"	"B2R8L5; B4DWR3; F5H2A7; hsa:7411; O55228; P61758; Q15765; Q5JT81; Q86X96"	"Cellular proteostasis"	"Prefoldin mediated transfer of substrate  to CCT/TriC"	"2"	"0"	"113.1"	"449.2"	"396.2"	"96.0"	"330.8"	"122.0"	"171.6"	"141.1"	"214.9"	"280.8"	"521.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7RTP6"	"[F-actin]-monooxygenase MICAL3 OS=Homo sapiens OX=9606 GN=MICAL3 PE=1 SV=2"	"1"	"3"	"5"	"3"	"2002"	"224.2"	"5.55"	"750.39"	"4.86"	"3"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00412, Pf01494, Pf12130"	"57553"	"ENSG00000243156"	"MICAL3"	"B2RXJ5; E9PEF0; hsa:57553; O94909; Q5U4P4; Q6ICK4; Q7RTP6; Q96DF2; Q9P2I3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P19404"	"NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV2 PE=1 SV=2"	"8"	"1"	"2"	"1"	"249"	"27.4"	"8.06"	"394.98"	"4.85"	"1"	"1"	"other metabolic processes;transport;developmental processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf01257"	"4729"	"ENSG00000178127"	"NDUFV2"	"hsa:4729; P19404; Q9BV41"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"12.7"	"46.2"	"42.5"	"11.9"	"39.5"	"15.9"	"39.3"	"25.2"	"53.7"	"49.9"	"96.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96BZ8"	"Leukocyte receptor cluster member 1 OS=Homo sapiens OX=9606 GN=LENG1 PE=1 SV=1"	"6"	"1"	"2"	"1"	"264"	"30.5"	"9.69"	"509.87"	"4.84"	"1"	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"19.4"	"30.7"	"30.8"	"15.4"	"26.1"	"20.4"	"65.7"	"48.0"	"63.5"	"93.0"	"98.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N806"	"Putative E3 ubiquitin-protein ligase UBR7 OS=Homo sapiens OX=9606 GN=UBR7 PE=1 SV=2"	"5"	"2"	"4"	"2"	"425"	"48.0"	"4.81"	"660.14"	"4.84"	"2"	"2"	"protein metabolism;other metabolic processes"	""	"other molecular function"	"Pf02207"	"55148"	"ENSG00000012963; ENSG00000278787"	"UBR7"	"hsa:55148; Q86U21; Q86UA9; Q8N806; Q96BY0; Q9NVV6"	""	""	"0"	"0"	"144.6"	"260.5"	"251.4"	"104.2"	"245.7"	"132.1"	"182.7"	"170.2"	"205.4"	"238.7"	"286.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04844"	"Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Homo sapiens OX=9606 GN=RPN2 PE=1 SV=3"	"3"	"1"	"2"	"1"	"631"	"69.2"	"5.69"	"504.06"	"4.82"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;ER/Golgi;nucleus;other cytoplasmic organelle"	"translation activity"	"Pf05817"	"6185"	"ENSG00000118705"	"RPN2"	"hsa:6185; P04844; Q5JYR6; Q6IBA5; Q96E21; Q9BUQ3; Q9UBE1"	"Proteasome degradation; N-glycan biosynthesis"	"SRP-dependent cotranslational protein targeting to membrane; Asparagine N-linked glycosylation; Maturation of spike protein"	"5"	"0"	"24.7"	"97.5"	"76.1"	"20.2"	"64.9"	"27.0"	"37.3"	"38.2"	"44.4"	"77.1"	"138.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2Q9"	"28S ribosomal protein S28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS28 PE=1 SV=1"	"10"	"2"	"4"	"2"	"187"	"20.8"	"9.10"	"528.01"	"4.82"	"2"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	""	"Pf10246"	"28957"	"ENSG00000147586"	"MRPS28"	"B2RDZ7; hsa:28957; Q96Q21; Q9Y2Q9"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"94.9"	"220.8"	"223.2"	"82.6"	"208.3"	"93.6"	"210.0"	"166.8"	"238.3"	"334.9"	"447.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WUA2"	"Peptidyl-prolyl cis-trans isomerase-like 4 OS=Homo sapiens OX=9606 GN=PPIL4 PE=1 SV=1"	"4"	"2"	"4"	"2"	"492"	"57.2"	"5.92"	"705.20"	"4.82"	"2"	"2"	"protein metabolism;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf00076, Pf00160"	"85313"	"ENSG00000131013"	"PPIL4"	"B2RD34; hsa:85313; Q7Z3Q5; Q8WUA2"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"56.5"	"126.1"	"145.7"	"52.3"	"129.8"	"65.0"	"147.4"	"123.4"	"214.3"	"281.2"	"411.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14531"	"Dihydropyrimidinase-related protein 4 OS=Homo sapiens OX=9606 GN=DPYSL4 PE=1 SV=2"	"3"	"2"	"3"	"2"	"572"	"61.8"	"7.09"	"387.98"	"4.81"	"1"	"2"	"developmental processes"	"cytosol"	"cytoskeletal activity;other molecular function"	"Pf01979"	"10570"	"ENSG00000151640"	"DPYSL4"	"B2RMQ1; D3DRG5; hsa:10570; O00240; O14531; Q5T0Q7"	""	"CRMPs in Sema3A signaling"	"1"	"0"	"27.2"	"170.5"	"115.7"	"15.2"	"102.9"	"20.7"	"47.0"	"38.5"	"53.8"	"84.3"	"171.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14241"	"Elongin-A OS=Homo sapiens OX=9606 GN=ELOA PE=1 SV=2"	"2"	"2"	"4"	"2"	"798"	"89.9"	"9.57"	"621.08"	"4.80"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf06881, Pf08711"	"6924"	"ENSG00000011007"	"ELOA"	"B2R7Q8; hsa:6924; Q14241; Q8IXH1"	"VEGFA-VEGFR2 signaling"	"TP53 Regulates Transcription of DNA Repair Genes; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events"	"12"	"0"	"113.5"	"236.5"	"226.2"	"95.3"	"221.8"	"112.9"	"291.4"	"324.9"	"686.1"	"1193.5"	"1906.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62820"	"Ras-related protein Rab-1A OS=Homo sapiens OX=9606 GN=RAB1A PE=1 SV=3"	"13"	"3"	"5"	"2"	"205"	"22.7"	"6.21"	"1006.58"	"4.80"	"3"	"2"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;other metabolic processes;stress response;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00071"	"5861"	"ENSG00000138069"	"RAB1A"	"hsa:5861; P11476; P62820; Q6FIE7; Q96N61; Q9Y3T2"	""	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport; RAB GEFs exchange GTP for GDP on RABs; RAB geranylgeranylation; COPII-mediated vesicle transport; Golgi Cisternae Pericentriolar Stack Reorganization"	"6"	"1"	"141.6"	"450.6"	"393.6"	"104.7"	"348.6"	"169.0"	"212.1"	"160.5"	"229.6"	"281.7"	"486.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00273"	"DNA fragmentation factor subunit alpha OS=Homo sapiens OX=9606 GN=DFFA PE=1 SV=1"	"6"	"2"	"3"	"2"	"331"	"36.5"	"4.79"	"242.47"	"4.79"	"1"	"2"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02017, Pf09033"	"1676"	"ENSG00000160049"	"DFFA"	"hsa:1676; O00273; Q5T6G5; Q5T6G6; Q96I97; Q9Y6C6"	"Apoptosis; Fas ligand pathway and stress induction of heat shock proteins; Acute viral myocarditis"	"Apoptosis induced DNA fragmentation"	"4"	"0"	"72.6"	"135.0"	"143.5"	"53.4"	"157.1"	"71.1"	"87.5"	"67.5"	"77.9"	"104.9"	"168.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NR09"	"Baculoviral IAP repeat-containing protein 6 OS=Homo sapiens OX=9606 GN=BIRC6 PE=1 SV=2"	"0"	"2"	"3"	"2"	"4857"	"529.9"	"6.05"	"268.89"	"4.79"	"1"	"2"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"4.1"	"14.7"	"16.0"	"4.2"	"15.5"	"7.5"	"8.3"	"8.2"	"9.7"	"18.8"	"19.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00746"	"Nucleoside diphosphate kinase, mitochondrial OS=Homo sapiens OX=9606 GN=NME4 PE=1 SV=1"	"9"	"1"	"2"	"1"	"187"	"20.6"	"10.29"	"438.15"	"4.76"	"1"	"1"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"kinase activity;other molecular function"	"Pf00334"	"4833"	"ENSG00000103202"	"NME4"	"A2IDD0; hsa:4833; O00746; Q5U0M9"	"Pyrimidine metabolism"	"Interconversion of nucleotide di- and triphosphates"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BYG3"	"MKI67 FHA domain-interacting nucleolar phosphoprotein OS=Homo sapiens OX=9606 GN=NIFK PE=1 SV=1"	"6"	"1"	"3"	"1"	"293"	"34.2"	"9.88"	"737.68"	"4.76"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf12196"	"84365"	"ENSG00000155438"	"NIFK"	"A8K788; hsa:84365; Q8TB66; Q96ED4; Q9BYG3"	""	""	"0"	"0"	"13.8"	"24.1"	"21.9"	"9.8"	"26.8"	"13.8"	"25.9"	"21.4"	"34.7"	"44.7"	"58.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05386"	"60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1"	"34"	"3"	"6"	"2"	"114"	"11.5"	"4.32"	"1772.96"	"4.75"	"3"	"1"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00428"	"6176"	"ENSG00000137818"	"RPLP1"	"A6NIB2; hsa:6176; P05386"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"212.4"	"689.0"	"756.1"	"260.7"	"635.2"	"335.8"	"880.5"	"609.8"	"919.6"	"969.6"	"1448.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y6B6"	"GTP-binding protein SAR1b OS=Homo sapiens OX=9606 GN=SAR1B PE=1 SV=1"	"8"	"1"	"2"	"1"	"198"	"22.4"	"6.11"	"488.72"	"4.74"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;ER/Golgi"	"other molecular function"	"Pf00025"	"51128"	"ENSG00000152700"	"SAR1B"	"D3DQA4; hsa:51128; Q567T4; Q9Y6B6"	"Sterol regulatory element-binding proteins (SREBP) signaling; Cholesterol metabolism; Enterocyte cholesterol metabolism"	"MHC class II antigen presentation; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; COPII-mediated vesicle transport; Cargo concentration in the ER; Regulation of cholesterol biosynthesis by SREBP (SREBF); Chylomicron assembly"	"10"	"0"	"50.6"	"59.9"	"63.4"	"31.0"	"54.8"	"45.8"	"32.4"	"32.4"	"34.0"	"49.1"	"42.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q02978"	"Mitochondrial 2-oxoglutarate/malate carrier protein OS=Homo sapiens OX=9606 GN=SLC25A11 PE=1 SV=3"	"5"	"1"	"2"	"1"	"314"	"34.0"	"9.91"	"492.89"	"4.74"	"1"	"1"	"other metabolic processes;transport"	"plasma membrane;other membranes;mitochondrion"	"transporter activity"	"Pf00153"	"8402"	"ENSG00000108528"	"SLC25A11"	"F5GY65; hsa:8402; O75537; Q02978; Q969P7"	"VEGFA-VEGFR2 signaling"	"Gluconeogenesis"	"2"	"0"	"49.2"	"152.8"	"133.2"	"45.1"	"127.5"	"55.0"	"85.8"	"59.8"	"74.8"	"116.6"	"151.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15532"	"Protein SSXT OS=Homo sapiens OX=9606 GN=SS18 PE=1 SV=3"	"3"	"1"	"2"	"1"	"418"	"45.9"	"6.46"	"518.18"	"4.73"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf05030"	"6760"	"ENSG00000141380"	"SS18"	"B0YJ95; hsa:6760; Q15532; Q16404; Q4VAX1; Q9BXC6"	""	""	"0"	"0"	"25.7"	"41.9"	"51.3"	"30.8"	"46.9"	"21.8"	"60.5"	"53.4"	"58.9"	"68.8"	"100.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UK76"	"Jupiter microtubule associated homolog 1 OS=Homo sapiens OX=9606 GN=JPT1 PE=1 SV=3"	"10"	"1"	"2"	"1"	"154"	"16.0"	"5.60"	"524.28"	"4.72"	"1"	"1"	""	"other membranes;nucleus;other cell component"	""	"Pf17054"	"51155"	"ENSG00000189159"	"JPT1"	"B2R6K3; hsa:51155; Q53FG7; Q7Z2D2; Q7Z2F0; Q9UK76"	""	""	"0"	"0"	"23.0"	"214.9"	"179.7"	"30.8"	"160.1"	"49.5"	"54.1"	"35.6"	"49.2"	"51.7"	"119.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14324"	"Farnesyl pyrophosphate synthase OS=Homo sapiens OX=9606 GN=FDPS PE=1 SV=4"	"5"	"2"	"4"	"2"	"419"	"48.2"	"6.15"	"555.74"	"4.72"	"2"	"2"	"other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00348"	"2224"	"ENSG00000160752"	"FDPS"	"D3DV91; E9PCI9; hsa:2224; P14324; Q96G29"	"Cholesterol biosynthesis pathway; Sterol regulatory element-binding proteins (SREBP) signaling; Mevalonate pathway; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Cholesterol synthesis disorders; Cholesterol metabolism; Enterocyte cholesterol metabolism"	"Activation of gene expression by SREBF (SREBP); Cholesterol biosynthesis"	"9"	"0"	"6.1"	"119.3"	"67.2"	"2.4"	"52.3"	"10.3"	"21.3"	"16.0"	"15.1"	"24.8"	"69.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NP79"	"Vacuolar protein sorting-associated protein VTA1 homolog OS=Homo sapiens OX=9606 GN=VTA1 PE=1 SV=1"	"9"	"2"	"3"	"2"	"307"	"33.9"	"6.29"	"742.12"	"4.72"	"2"	"1"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	""	"Pf04652, Pf18097"	"51534"	"ENSG00000009844"	"VTA1"	"B4DW55; E1P594; E7ETQ7; hsa:51534; Q5TGM1; Q6IAE8; Q9H0R2; Q9H3K9; Q9NP79; Q9P0Q0"	""	"Endosomal Sorting Complex Required For Transport (ESCRT); Budding and maturation of HIV virion"	"2"	"0"	"74.6"	"227.0"	"196.4"	"66.4"	"198.0"	"86.9"	"144.0"	"109.4"	"147.4"	"205.7"	"329.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P20073"	"Annexin A7 OS=Homo sapiens OX=9606 GN=ANXA7 PE=1 SV=3"	"3"	"2"	"3"	"2"	"488"	"52.7"	"5.68"	"279.36"	"4.71"	"1"	"2"	"other metabolic processes;other biological processes"	"other membranes;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00191"	"310"	"ENSG00000138279"	"ANXA7"	"hsa:310; P20073; Q5F2H3; Q5T0M6; Q5T0M7"	"11p11.2 copy number variation syndrome"	""	"1"	"0"	"37.1"	"104.3"	"102.0"	"28.3"	"98.8"	"50.0"	"85.5"	"64.7"	"78.8"	"119.9"	"132.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BYI3"	"Hyccin OS=Homo sapiens OX=9606 GN=FAM126A PE=1 SV=2"	"4"	"2"	"4"	"2"	"521"	"57.6"	"8.16"	"510.77"	"4.70"	"2"	"2"	"other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf09790"	"84668"	"ENSG00000122591"	"HYCC1"	"A0A024RA06; A4D145; B8ZZJ1; hsa:84668; Q6N010; Q75MR4; Q7LDZ4; Q96MX1; Q96NQ6; Q9BYI3"	""	""	"0"	"0"	"8.4"	"16.3"	"15.9"	"7.6"	"16.5"	"5.8"	"12.1"	"13.5"	"42.9"	"66.4"	"76.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P15927"	"Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2 PE=1 SV=1"	"8"	"1"	"1"	"1"	"270"	"29.2"	"6.15"	""	"4.68"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf08784"	"6118"	"ENSG00000117748"	"RPA2"	"hsa:6118; P15927; Q52II0; Q5TEI9; Q5TEJ5"	"miRNA regulation of DNA damage response; Retinoblastoma gene in cancer; G1 to S cell cycle control; DNA replication; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair; DNA damage response"	"Fanconi Anemia Pathway; Regulation of HSF1-mediated heat shock response; Regulation of TP53 Activity through Phosphorylation; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Meiotic recombination; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; HSF1 activation; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Removal of the Flap Intermediate; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"38"	"0"	"6.0"	"23.1"	"21.9"	"6.0"	"17.3"	"7.8"	"13.7"	"8.9"	"11.8"	"11.8"	"26.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94874"	"E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2"	"3"	"2"	"4"	"2"	"794"	"89.5"	"6.79"	"576.69"	"4.67"	"2"	"2"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf09743"	"23376"	"ENSG00000014123"	"UFL1"	"A0PJ53; B4DJ57; C0H5X5; hsa:23376; O94874; Q8N765; Q9NTQ0"	""	"Antigen processing: Ubiquitination & Proteasome degradation"	"1"	"0"	"23.8"	"70.7"	"68.0"	"14.7"	"52.1"	"24.3"	"55.3"	"46.2"	"57.8"	"95.9"	"168.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95825"	"Quinone oxidoreductase-like protein 1 OS=Homo sapiens OX=9606 GN=CRYZL1 PE=1 SV=2"	"9"	"2"	"3"	"2"	"349"	"38.7"	"5.78"	"252.87"	"4.62"	"1"	"2"	"other metabolic processes"	""	"other molecular function"	""	"9946"	"ENSG00000205758"	"CRYZL1"	"B2RDX1; B3KQ77; hsa:9946; O95825; Q96DY0; Q9NVY7"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WXH0"	"Nesprin-2 OS=Homo sapiens OX=9606 GN=SYNE2 PE=1 SV=3"	"0"	"2"	"3"	"1"	"6885"	"795.9"	"5.36"	"250.45"	"4.62"	"1"	"2"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00435, Pf10541"	"23224"	"ENSG00000054654"	"SYNE2"	"B4DND7; B4DPR6; hsa:23224; I6XXQ5; Q540G1; Q86YP9; Q8N1S3; Q8NF49; Q8TER7; Q8WWW3; Q8WWW4; Q8WWW5; Q8WXH0; Q8WXH1; Q9NU50; Q9UFQ4; Q9Y2L4; Q9Y4R1"	"Ovarian infertility; Rett syndrome causing genes; Envelope proteins and their potential roles in EDMD physiopathology"	"Meiotic synapsis"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55809"	"Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial OS=Homo sapiens OX=9606 GN=OXCT1 PE=1 SV=1"	"4"	"1"	"1"	"1"	"520"	"56.1"	"7.46"	""	"4.61"	""	"1"	"other metabolic processes;stress response;developmental processes;other biological processes"	"mitochondrion"	"other molecular function"	"Pf01144"	"5019"	"ENSG00000083720"	"OXCT1"	"B2R5V2; B7Z528; hsa:5019; P55809"	""	"Utilization of Ketone Bodies"	"1"	"0"	"16.3"	"30.5"	"30.6"	"11.8"	"26.3"	"14.9"	"22.0"	"16.6"	"27.1"	"34.0"	"40.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96GM8"	"Target of EGR1 protein 1 OS=Homo sapiens OX=9606 GN=TOE1 PE=1 SV=1"	"4"	"2"	"3"	"2"	"510"	"56.5"	"7.18"	"277.20"	"4.60"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00642, Pf04857"	"114034"	"ENSG00000132773"	"TOE1"	"B4DEM6; hsa:114034; Q6IA35; Q8IWN5; Q96GM8; Q9H846"	""	""	"0"	"0"	"11.4"	"32.3"	"26.1"	"10.1"	"27.3"	"15.0"	"24.7"	"20.9"	"21.4"	"29.4"	"42.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P68402"	"Platelet-activating factor acetylhydrolase IB subunit beta OS=Homo sapiens OX=9606 GN=PAFAH1B2 PE=1 SV=1"	"7"	"2"	"4"	"2"	"229"	"25.6"	"5.92"	"532.55"	"4.59"	"2"	"2"	"other metabolic processes;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf13472"	"5049"	"ENSG00000168092"	"PAFAH1B2"	"A8DPS5; A8DPS6; A8DPS7; E9PEJ5; E9PLP3; hsa:5049; O00687; P68402; Q29459; Q6IBR6"	""	"COPI-independent Golgi-to-ER retrograde traffic; Neutrophil degranulation"	"2"	"0"	"59.6"	"354.3"	"347.4"	"28.3"	"327.1"	"93.0"	"115.0"	"69.7"	"115.0"	"138.3"	"275.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86X10"	"Ral GTPase-activating protein subunit beta OS=Homo sapiens OX=9606 GN=RALGAPB PE=1 SV=1"	"1"	"1"	"2"	"1"	"1494"	"166.7"	"6.79"	"494.07"	"4.58"	"1"	"1"	"other biological processes"	""	"enzyme regulator activity;other molecular function"	"Pf20412"	"57148"	"ENSG00000170471"	"RALGAPB"	"A2A2E8; A2A2E9; hsa:57148; Q5TG31; Q86X10; Q8N3D1; Q8WWC0; Q9H3X8; Q9UJR1; Q9ULK1; Q9Y3G9"	""	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"	"1"	"0"	"7.9"	"22.4"	"19.0"	"11.8"	"24.3"	"11.5"	"30.2"	"29.2"	"142.6"	"195.2"	"226.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H3P7"	"Golgi resident protein GCP60 OS=Homo sapiens OX=9606 GN=ACBD3 PE=1 SV=4"	"3"	"1"	"2"	"1"	"528"	"60.6"	"5.06"	"452.22"	"4.57"	"1"	"1"	"other metabolic processes"	"other membranes;mitochondrion;ER/Golgi"	"other molecular function"	"Pf00887, Pf13897"	"64746"	"ENSG00000182827"	"ACBD3"	"B2RB29; hsa:64746; Q5VTJ0; Q6P9F1; Q8IZC5; Q8N4D6; Q9H3P7; Q9H6U3"	""	"Golgi Associated Vesicle Biogenesis"	"1"	"0"	"71.3"	"150.6"	"143.1"	"61.4"	"137.9"	"68.1"	"89.4"	"64.1"	"103.7"	"136.4"	"182.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43432"	"Eukaryotic translation initiation factor 4 gamma 3 OS=Homo sapiens OX=9606 GN=EIF4G3 PE=1 SV=2"	"1"	"2"	"4"	"1"	"1585"	"176.5"	"5.38"	"550.14"	"4.56"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf02020, Pf02847, Pf02854"	"8672"	"ENSG00000075151"	"EIF4G3"	"B9EGQ7; hsa:8672; O43432; Q15597; Q504Z1; Q5SWC3; Q8NEN1"	"Translation factors; Translation inhibitors in chronically activated PDGFRA cells"	"ISG15 antiviral mechanism"	"3"	"0"	"76.7"	"123.1"	"137.2"	"57.0"	"143.0"	"64.9"	"182.1"	"123.3"	"169.6"	"202.5"	"309.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IWZ3"	"Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1"	"1"	"4"	"5"	"3"	"2542"	"269.3"	"5.73"	"837.07"	"4.56"	"3"	"2"	"stress response"	"other cell component"	""	"Pf00013, Pf12796"	"404734; 54882"	"ENSG00000131503"	"ANKHD1"	"A6NH85; hsa:404734; hsa:54882; Q149P2; Q8IWZ2; Q8IWZ3; Q8WY90; Q96G77; Q96GK0; Q9H2U0; Q9HA95; Q9NWG4; Q9UPR7"	""	""	"0"	"0"	"41.6"	"47.7"	"68.4"	"31.0"	"78.1"	"56.2"	"63.8"	"38.8"	"69.0"	"94.9"	"127.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N414"	"PiggyBac transposable element-derived protein 5 OS=Homo sapiens OX=9606 GN=PGBD5 PE=1 SV=4"	"3"	"1"	"2"	"1"	"524"	"58.4"	"8.85"	"398.68"	"4.54"	"1"	"1"	"DNA metabolism;other metabolic processes"	"nucleus"	"other molecular function"	"Pf13843"	"79605"	"ENSG00000177614"	"PGBD5"	"A0A0A0MS21; A0PJF3; B4DM72; B7Z9K3; B9EK58; hsa:79605; Q5SR37; Q6PJN2; Q8N414; U3REJ1"	"Clear cell renal cell carcinoma pathways"	""	"1"	"0"	"9.9"	"7.4"	"9.3"	"9.1"	"15.4"	"6.0"	"21.6"	"35.7"	"43.7"	"74.0"	"30.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13051"	"Uracil-DNA glycosylase OS=Homo sapiens OX=9606 GN=UNG PE=1 SV=2"	"7"	"1"	"1"	"1"	"313"	"34.6"	"9.32"	""	"4.54"	""	"1"	"DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"mitochondrion;nucleus"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf03167"	"7374"	"ENSG00000076248"	"UNG"	"A8K5M6; B2R8Y1; hsa:7374; O00637; O00719; P13051; Q93028"	"Base excision repair; DNA repair pathways, full network"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3D2"	"Methionine-R-sulfoxide reductase B2, mitochondrial OS=Homo sapiens OX=9606 GN=MSRB2 PE=1 SV=2"	"5"	"1"	"2"	"1"	"182"	"19.5"	"8.63"	"383.16"	"4.53"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response"	"cytosol;mitochondrion;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01641"	"22921"	"ENSG00000148450"	"MSRB2"	"hsa:22921; Q17R44; Q4G1C7; Q9Y3D2; Q9Y5W6"	"Sulindac metabolic pathway; Methionine de novo and salvage pathway"	"Protein repair"	"3"	"0"	"59.8"	"93.8"	"79.6"	"32.6"	"78.6"	"47.5"	"72.7"	"69.4"	"88.0"	"103.9"	"158.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75179"	"Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3"	"1"	"2"	"4"	"1"	"2603"	"274.1"	"6.52"	"544.07"	"4.52"	"2"	"2"	"stress response;developmental processes;other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf00013, Pf12796"	"26057"	"ENSG00000132466"	"ANKRD17"	"E7EUV3; G5E964; hsa:26057; O75179; Q6PJ85; Q6PK85; Q6PKA2; Q86XI3; Q8NDR5; Q96I86; Q9H288; Q9H6J9"	""	""	"0"	"0"	"3.2"	"14.3"	"16.6"	"2.6"	"11.3"	"2.4"	"14.5"	"12.7"	"28.4"	"33.2"	"55.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EV2"	"RNA-binding protein 33 OS=Homo sapiens OX=9606 GN=RBM33 PE=1 SV=3"	"2"	"1"	"2"	"1"	"1170"	"129.9"	"6.93"	"634.68"	"4.51"	"1"	"1"	""	""	""	""	"155435"	"ENSG00000184863"	"RBM33"	"A4D244; B5MC24; hsa:155435; Q52LF5; Q75LN9; Q75ML5; Q96EV2; Q9NSV0"	""	""	"0"	"0"	"33.5"	"57.2"	"67.1"	"27.8"	"63.4"	"38.8"	"124.3"	"85.8"	"130.1"	"136.5"	"168.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15758"	"Neutral amino acid transporter B(0) OS=Homo sapiens OX=9606 GN=SLC1A5 PE=1 SV=2"	"4"	"1"	"2"	"1"	"541"	"56.6"	"5.48"	"500.43"	"4.50"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;other cell component"	"transporter activity;other molecular function"	"Pf00375"	"6510"	"ENSG00000105281"	"SLC1A5"	"A8K9H5; B4DR77; B4DWS4; B7ZB81; D0EYG6; E9PC01; hsa:6510; O95720; Q15758; Q96RL9; Q9BWQ3; Q9UNP2"	"TYROBP causal network in microglia; mRNA, protein, and metabolite inducation pathway by cyclosporin A; Metabolic reprogramming in colon cancer; Ferroptosis; Amino acid metabolism in triple-negative breast cancer cells"	"RHOH GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RAC3 GTPase cycle; RHOJ GTPase cycle; Amino acid transport across the plasma membrane"	"11"	"0"	"16.4"	"60.8"	"66.5"	"12.9"	"51.4"	"21.4"	"31.8"	"24.4"	"38.9"	"55.5"	"77.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96A72"	"Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1"	"14"	"2"	"3"	"2"	"148"	"17.3"	"6.39"	"239.90"	"4.48"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf02792"	"55110"	"ENSG00000111196"	"MAGOHB"	"hsa:55110; Q96A72"	""	"Regulation of expression of SLITs and ROBOs; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	"6"	"0"	"19.5"	"73.9"	"72.0"	"23.3"	"67.6"	"26.6"	"39.8"	"33.9"	"49.6"	"77.1"	"106.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60953"	"Cell division control protein 42 homolog OS=Homo sapiens OX=9606 GN=CDC42 PE=1 SV=2"	"6"	"1"	"2"	"1"	"191"	"21.2"	"6.55"	"547.47"	"4.47"	"1"	"1"	"cell-cell signaling;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00071"	"998"	"ENSG00000070831"	"CDC42"	"hsa:998; P21181; P25763; P60953; Q7L8R5; Q9UDI2"	"Androgen receptor signaling pathway; Target of rapamycin signaling; Integrin-mediated cell adhesion; RANKL/RANK signaling pathway; Leptin signaling pathway; Microtubule cytoskeleton regulation; Metastatic brain tumor; Pathogenic Escherichia coli infection; RalA downstream regulated genes; B cell receptor signaling pathway; AGE/RAGE pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Spinal cord injury; Focal adhesion; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Oxidative damage response; p38 MAPK signaling pathway; Ebola virus infection in host; Ras signaling; Pancreatic adenocarcinoma pathway; EGF/EGFR signaling pathway; Nonalcoholic fatty liver disease; Hippo signaling regulation pathways; 22q11.2 copy number variation syndrome; Gastrin signaling pathway; Regulation of actin cytoskeleton; G13 signaling pathway; Genetic causes of porto-sinusoidal vascular disease; T-cell receptor signaling pathway; DNA damage response (only ATM dependent)"	"RAC1 GTPase cycle; RHOG GTPase cycle; MAPK6/MAPK4 signaling; EGFR downregulation; CDC42 GTPase cycle; RHOQ GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOJ GTPase cycle; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; RHO GTPases activate IQGAPs; RHO GTPases Activate Formins; EPHB-mediated forward signaling; VEGFA-VEGFR2 Pathway; Factors involved in megakaryocyte development and platelet production; RHOV GTPase cycle; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; RHOU GTPase cycle; DCC mediated attractive signaling; GPVI-mediated activation cascade; Myogenesis; G beta:gamma signalling through CDC42; RHO GTPases activate PAKs; Inactivation of CDC42 and RAC1; CD28 dependent Vav1 pathway; RHO GTPases activate KTN1"	"60"	"0"	"94.9"	"287.2"	"306.2"	"62.5"	"269.0"	"114.5"	"216.4"	"219.4"	"377.2"	"410.3"	"779.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99873"	"Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3"	"4"	"1"	"2"	"1"	"371"	"42.4"	"5.35"	"342.20"	"4.45"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13649"	"3276"	"ENSG00000126457"	"PRMT1"	"A0A087X1W2; B4E3C3; G5E9B6; H7C2I1; hsa:3276; Q15529; Q2VP93; Q6LEU5; Q8WUW5; Q99872; Q99873; Q99874; Q9NZ04; Q9NZ05; Q9NZ06"	"Energy metabolism; mRNA processing; Nitric oxide metabolism in cystic fibrosis; 16p11.2 distal deletion syndrome; Interferon type I signaling pathways"	"Extra-nuclear estrogen signaling; Estrogen-dependent gene expression; RMTs methylate histone arginines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Maturation of nucleoprotein"	"11"	"0"	"26.9"	"78.5"	"74.4"	"21.4"	"63.7"	"30.6"	"46.7"	"29.6"	"48.3"	"54.5"	"104.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94776"	"Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"668"	"75.0"	"9.66"	"409.35"	"4.44"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00320, Pf01426, Pf01448, Pf17226"	"9219"	"ENSG00000149480"	"MTA2"	"hsa:9219; O94776; Q68DB1; Q9UQB5"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"Potential therapeutics for SARS; Regulation of PTEN gene transcription; HDACs deacetylate histones; RNA Polymerase I Transcription Initiation; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of TP53 Activity through Acetylation"	"7"	"0"	"43.6"	"126.4"	"124.8"	"41.5"	"95.2"	"54.6"	"77.7"	"56.3"	"92.6"	"112.9"	"158.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96DR8"	"Mucin-like protein 1 OS=Homo sapiens OX=9606 GN=MUCL1 PE=1 SV=1"	"18"	"2"	"3"	"2"	"90"	"9.0"	"4.64"	"259.15"	"4.42"	"1"	"2"	""	"non-structural extracellular;plasma membrane;other membranes;ER/Golgi"	""	""	"118430"	"ENSG00000172551"	"MUCL1"	"hsa:118430; Q0VG95; Q32ZB5; Q96DR8"	""	"Dectin-2 family; Termination of O-glycan biosynthesis; Defective GALNT3 causes HFTC; Defective C1GALT1C1 causes TNPS; Defective GALNT12 causes CRCS1"	"6"	"0"	"247.6"	"249.3"	"285.7"	"168.5"	"254.8"	"168.1"	"628.1"	"466.5"	"622.7"	"673.0"	"782.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"C9JLW8"	"Mapk-regulated corepressor-interacting protein 1 OS=Homo sapiens OX=9606 GN=MCRIP1 PE=1 SV=1"	"11"	"1"	"2"	"1"	"97"	"10.9"	"9.41"	"385.85"	"4.40"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	""	"Pf14799"	"348262"	"ENSG00000225663; ENSG00000288213"	"MCRIP1"	"C9JLW8; hsa:348262; Q6ZUL0"	""	""	"0"	"0"	"20.6"	"51.7"	"63.3"	"29.8"	"67.7"	"22.4"	"62.3"	"45.7"	"68.6"	"65.0"	"76.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07108"	"Acyl-CoA-binding protein OS=Homo sapiens OX=9606 GN=DBI PE=1 SV=2"	"23"	"1"	"2"	"1"	"87"	"10.0"	"6.57"	"498.36"	"4.39"	"1"	"1"	"other metabolic processes;other biological processes"	"ER/Golgi;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00887"	"1622"	"ENSG00000155368"	"DBI"	"B8ZWD2; B8ZWD6; B8ZWD7; hsa:1622; P07108; P08869; Q4VWZ6; Q53SQ7; Q6IB48; Q9UCI8"	"Sterol regulatory element-binding proteins (SREBP) signaling; PPAR-alpha pathway; Nuclear receptors meta-pathway; PPAR signaling pathway; Fatty acid transporters"	"Mitochondrial Fatty Acid Beta-Oxidation"	"6"	"0"	"9.2"	"153.0"	"137.7"	"6.9"	"133.2"	"36.3"	"28.1"	"19.6"	"24.6"	"28.3"	"95.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NQI0"	"Probable ATP-dependent RNA helicase DDX4 OS=Homo sapiens OX=9606 GN=DDX4 PE=1 SV=2"	"3"	"2"	"3"	"1"	"724"	"79.3"	"5.87"	"238.88"	"4.39"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"54514"	"ENSG00000152670"	"DDX4"	"A8K8Q2; B3KSF4; D6RDK4; E9PCD8; hsa:54514; Q5M7Z3; Q86VX0; Q9NQI0; Q9NT92; Q9NYB1"	"Male infertility"	"RND3 GTPase cycle; PIWI-interacting RNA (piRNA) biogenesis"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13405"	"39S ribosomal protein L49, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL49 PE=1 SV=1"	"11"	"2"	"3"	"2"	"166"	"19.2"	"9.45"	"258.50"	"4.38"	"1"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf05046"	"740"	"ENSG00000149792"	"MRPL49"	"B2R4G6; hsa:740; Q13405"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"4.1"	"21.7"	"20.7"	"6.1"	"15.7"	"9.3"	"15.0"	"8.4"	"15.9"	"32.5"	"33.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96CN7"	"Isochorismatase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ISOC1 PE=1 SV=3"	"5"	"1"	"2"	"1"	"298"	"32.2"	"7.39"	"382.70"	"4.37"	"1"	"1"	""	"other cytoplasmic organelle;other cell component"	""	"Pf00857"	"51015"	"ENSG00000066583"	"ISOC1"	"hsa:51015; Q7Z770; Q96CN7"	""	""	"0"	"0"	"27.8"	"117.0"	"104.2"	"30.0"	"112.3"	"42.3"	"62.6"	"46.1"	"58.9"	"63.9"	"132.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BRT2"	"Ubiquinol-cytochrome-c reductase complex assembly factor 2 OS=Homo sapiens OX=9606 GN=UQCC2 PE=1 SV=1"	"10"	"1"	"2"	"1"	"126"	"14.9"	"7.37"	"344.02"	"4.35"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"other membranes;mitochondrion;nucleus"	""	"Pf20180"	"84300"	"ENSG00000137288"	"UQCC2"	"B2R4I0; hsa:84300; Q9BRT2"	"Mitochondrial complex III assembly"	""	"1"	"0"	"11.8"	"40.7"	"36.1"	"9.6"	"32.4"	"13.4"	"25.8"	"42.2"	"62.9"	"92.4"	"198.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12765"	"Secernin-1 OS=Homo sapiens OX=9606 GN=SCRN1 PE=1 SV=2"	"3"	"1"	"3"	"1"	"414"	"46.4"	"4.75"	"490.29"	"4.35"	"1"	"1"	"protein metabolism;transport;other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf03577"	"9805"	"ENSG00000136193"	"SCRN1"	"A8K0E9; B4DHM0; B4DIP5; C9JPG0; hsa:9805; Q12765; Q25QX7; Q8IWD1"	""	""	"0"	"0"	"22.7"	"127.8"	"125.9"	"18.4"	"108.7"	"35.0"	"47.2"	"28.8"	"42.8"	"56.0"	"125.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BV81"	"ER membrane protein complex subunit 6 OS=Homo sapiens OX=9606 GN=EMC6 PE=1 SV=1"	"12"	"1"	"2"	"1"	"110"	"12.0"	"10.07"	"420.12"	"4.35"	"1"	"1"	"cell organization and biogenesis;other metabolic processes"	"other membranes;ER/Golgi"	""	"Pf07019"	"83460"	"ENSG00000127774"	"EMC6"	"hsa:83460; Q9BV81"	""	""	"0"	"0"	"6.0"	"17.1"	"13.7"	"7.2"	"10.6"	"6.0"	"11.2"	"13.9"	"12.6"	"20.5"	"34.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75934"	"Pre-mRNA-splicing factor SPF27 OS=Homo sapiens OX=9606 GN=BCAS2 PE=1 SV=1"	"6"	"1"	"2"	"1"	"225"	"26.1"	"5.66"	"429.42"	"4.33"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytoskeleton;nucleus;other cell component"	""	"Pf05700"	"10286"	"ENSG00000116752"	"BCAS2"	"hsa:10286; O75934; Q6FGS0"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"22.8"	"60.5"	"59.9"	"30.6"	"55.4"	"26.6"	"79.9"	"99.9"	"99.9"	"123.3"	"237.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14696"	"LRP chaperone MESD OS=Homo sapiens OX=9606 GN=MESD PE=1 SV=2"	"10"	"2"	"4"	"2"	"234"	"26.1"	"7.78"	"606.75"	"4.33"	"2"	"2"	"cell-cell signaling;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi"	"signal transduction activity or receptor binding;other molecular function"	"Pf10185"	"23184"	"ENSG00000117899"	"MESD"	"B4DW84; D3DW96; hsa:23184; Q14696; Q969U1"	""	""	"0"	"0"	"50.3"	"66.7"	"68.6"	"30.4"	"66.0"	"45.2"	"71.1"	"43.3"	"75.1"	"71.7"	"84.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N3I7"	"Bardet-Biedl syndrome 5 protein OS=Homo sapiens OX=9606 GN=BBS5 PE=1 SV=1"	"5"	"1"	"2"	"1"	"341"	"38.7"	"5.60"	"375.58"	"4.33"	"1"	"1"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf07289"	"129880"	"ENSG00000163093"	"BBS5"	"D3DPC3; hsa:129880; Q6PKN0; Q8N3I7"	"Ciliary landscape; Genes related to primary cilium development (based on CRISPR); Joubert syndrome; Ciliopathies; Bardet-Biedl syndrome"	"BBSome-mediated cargo-targeting to cilium"	"6"	"0"	"19.2"	"31.5"	"39.9"	"18.7"	"33.2"	"22.3"	"41.7"	"34.8"	"57.2"	"72.3"	"95.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P00918"	"Carbonic anhydrase 2 OS=Homo sapiens OX=9606 GN=CA2 PE=1 SV=2"	"6"	"1"	"2"	"1"	"260"	"29.2"	"7.40"	"523.92"	"4.33"	"1"	"1"	"transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00194"	"760"	"ENSG00000104267"	"CA2"	"B2R7G8; hsa:760; P00918; Q6FI12; Q96ET9"	"Proximal tubule transport"	"Reversible hydration of carbon dioxide; Erythrocytes take up carbon dioxide and release oxygen; Erythrocytes take up oxygen and release carbon dioxide"	"4"	"0"	"13.5"	"57.3"	"58.6"	"9.3"	"49.4"	"21.6"	"25.0"	"22.9"	"28.8"	"35.8"	"54.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43615"	"Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2"	"6"	"2"	"3"	"2"	"452"	"51.3"	"8.32"	"252.76"	"4.32"	"1"	"2"	"cell organization and biogenesis;transport"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf04280"	"10469"	"ENSG00000104980"	"TIMM44"	"A8K0R9; D6W664; hsa:10469; O43615; Q8N193"	""	"Mitochondrial protein import"	"1"	"0"	"3.3"	"16.6"	"12.0"	"3.0"	"8.7"	"8.0"	"10.9"	"10.4"	"11.4"	"18.9"	"24.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43824"	"Putative GTP-binding protein 6 OS=Homo sapiens OX=9606 GN=GTPBP6 PE=2 SV=4"	"3"	"1"	"2"	"1"	"516"	"56.9"	"9.42"	"415.77"	"4.31"	"1"	"1"	""	"other cell component"	"translation activity;other molecular function"	"Pf01926, Pf13167, Pf16360"	"8225"	"ENSG00000178605"	"GTPBP6"	"H0Y2S1; hsa:8225; O43824; Q53F77; Q5HYX8"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P18887"	"DNA repair protein XRCC1 OS=Homo sapiens OX=9606 GN=XRCC1 PE=1 SV=2"	"5"	"2"	"4"	"2"	"633"	"69.4"	"6.39"	"800.99"	"4.31"	"2"	"2"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"70.4"	"130.7"	"134.8"	"50.4"	"138.6"	"67.5"	"277.8"	"210.4"	"293.3"	"290.6"	"377.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P00441"	"Superoxide dismutase [Cu-Zn] OS=Homo sapiens OX=9606 GN=SOD1 PE=1 SV=2"	"13"	"2"	"3"	"2"	"154"	"15.9"	"6.13"	"714.93"	"4.29"	"2"	"1"	"cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"non-structural extracellular;cytosol;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00080"	"6647"	"ENSG00000142168"	"SOD1"	"A6NHJ0; D3DSE4; hsa:6647; P00441; Q16669; Q16711; Q16838; Q16839; Q16840; Q6NR85"	"Selenium micronutrient network; Vitamin B12 metabolism; Folate metabolism; AGE/RAGE pathway; Dopamine metabolism; Amyotrophic lateral sclerosis (ALS); Trans-sulfuration, one-carbon metabolism and related pathways; Copper homeostasis; Physico-chemical features and toxicity-associated pathways; Oxidative stress response; Extracellular vesicles in the crosstalk of cardiac cells; Arsenic metabolism and reactive oxygen species generation"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Platelet degranulation ; Detoxification of Reactive Oxygen Species"	"15"	"0"	"179.6"	"1042.0"	"890.3"	"142.0"	"792.2"	"267.8"	"500.3"	"364.7"	"466.9"	"570.3"	"1188.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99986"	"Serine/threonine-protein kinase VRK1 OS=Homo sapiens OX=9606 GN=VRK1 PE=1 SV=1"	"4"	"1"	"2"	"1"	"396"	"45.4"	"8.91"	"357.53"	"4.27"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;ER/Golgi;nucleus"	"kinase activity;other molecular function"	"Pf00069"	"7443"	"ENSG00000100749"	"VRK1"	"hsa:7443; Q3SYL2; Q99986"	""	"Initiation of Nuclear Envelope (NE) Reformation; Nuclear Envelope Breakdown"	"2"	"0"	"11.1"	"22.9"	"25.9"	"8.5"	"18.1"	"11.1"	"43.2"	"30.1"	"49.2"	"92.5"	"173.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04792"	"Heat shock protein beta-1 OS=Homo sapiens OX=9606 GN=HSPB1 PE=1 SV=2"	"8"	"1"	"2"	"1"	"205"	"22.8"	"6.40"	"379.92"	"4.24"	"1"	"1"	"stress response;transport;signal transduction;other biological processes"	"plasma membrane;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00011"	"3315"	"ENSG00000106211"	"HSPB1"	"B2R4N8; hsa:3315; P04792; Q6FI47; Q96C20; Q96EI7; Q9UC31; Q9UC34; Q9UC35; Q9UC36"	"Apoptosis-related network due to altered Notch3 in ovarian cancer; Fas ligand pathway and stress induction of heat shock proteins; MAPK signaling pathway; ATM signaling in development and disease ; VEGFA-VEGFR2 signaling; p38 MAPK signaling pathway; Extracellular vesicles in the crosstalk of cardiac cells; Ferroptosis; IL-18 signaling pathway; Intracellular trafficking proteins involved in CMT neuropathy; GDNF signaling; A network map of Macrophage-stimulating protein (MSP) signaling"	"AUF1 (hnRNP D0) binds and destabilizes mRNA; MAPK6/MAPK4 signaling; Extra-nuclear estrogen signaling; VEGFA-VEGFR2 Pathway"	"16"	"0"	"15.0"	"30.1"	"38.4"	"11.1"	"32.4"	"15.5"	"30.4"	"29.6"	"42.1"	"54.6"	"56.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBW8"	"COP9 signalosome complex subunit 7a OS=Homo sapiens OX=9606 GN=COPS7A PE=1 SV=1"	"5"	"1"	"2"	"1"	"275"	"30.3"	"8.22"	"454.91"	"4.24"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf01399, Pf18392"	"50813"	"ENSG00000111652"	"COPS7A"	"A8K9A6; hsa:50813; Q9NVX3; Q9UBW8; Q9UJW4"	"Ciliary landscape"	"Cargo recognition for clathrin-mediated endocytosis; Formation of TC-NER Pre-Incision Complex; Neddylation; DNA Damage Recognition in GG-NER"	"5"	"0"	"14.9"	"50.7"	"40.0"	"17.5"	"37.2"	"15.7"	"30.0"	"28.5"	"41.5"	"59.4"	"67.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49821"	"NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV1 PE=1 SV=4"	"4"	"2"	"3"	"2"	"464"	"50.8"	"8.21"	"272.47"	"4.23"	"1"	"2"	"other metabolic processes;transport"	"other membranes;cytosol;mitochondrion"	"transporter activity;other molecular function"	"Pf01512, Pf10531, Pf10589"	"4723"	"ENSG00000167792"	"NDUFV1"	"hsa:4723; O60924; O60940; P49821; Q16104; Q6IBR3; Q96BF8; Q96HS7"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14733"	"Dual specificity mitogen-activated protein kinase kinase 7 OS=Homo sapiens OX=9606 GN=MAP2K7 PE=1 SV=2"	"4"	"1"	"2"	"1"	"419"	"47.5"	"9.16"	"322.38"	"4.22"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"5609"	"ENSG00000076984"	"MAP2K7"	"B2R9S5; D6W659; hsa:5609; O14648; O14733; O14816; O60452; O60453; Q1PG43; Q8IY10"	"MicroRNAs in cardiomyocyte hypertrophy; IL-1 signaling pathway; RANKL/RANK signaling pathway; Alzheimer's disease and miRNA effects; Glioblastoma signaling pathways; TNF-alpha signaling pathway; Interleukin-1 (IL-1) structural pathway; Cardiac hypertrophic response; MAPK signaling pathway; ERK pathway in Huntington's disease; T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; MAPK cascade; Translation inhibitors in chronically activated PDGFRA cells; Hepatitis B infection; IL-18 signaling pathway; Insulin signaling; Host-pathogen interaction of human coronaviruses - MAPK signaling; Pleural mesothelioma; Alzheimer's disease; ErbB signaling pathway; Toll-like receptor signaling pathway"	"FCERI mediated MAPK activation; Oxidative Stress Induced Senescence; JNK (c-Jun kinases) phosphorylation and  activation mediated by activated human TAK1; Uptake and function of anthrax toxins"	"27"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N5N7"	"39S ribosomal protein L50, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL50 PE=1 SV=2"	"13"	"1"	"2"	"1"	"158"	"18.3"	"7.88"	"325.37"	"4.21"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;cytosol;mitochondrion;translational apparatus"	""	"Pf10501"	"54534"	"ENSG00000136897"	"MRPL50"	"B7Z358; hsa:54534; Q5T7E0; Q8N5N7; Q9NX15"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TEA8"	"D-aminoacyl-tRNA deacylase 1 OS=Homo sapiens OX=9606 GN=DTD1 PE=1 SV=2"	"8"	"1"	"2"	"1"	"209"	"23.4"	"8.24"	"422.70"	"4.21"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02580"	"92675"	"ENSG00000125821"	"DTD1"	"A8K5X5; D3DW37; hsa:92675; Q496D1; Q5W184; Q8TEA8; Q8WXU8; Q9BW67; Q9H464; Q9H474"	""	""	"0"	"0"	"11.6"	"15.6"	"16.7"	"10.6"	"14.2"	"9.9"	"29.9"	"19.9"	"32.8"	"33.7"	"48.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15514"	"DNA-directed RNA polymerase II subunit RPB4 OS=Homo sapiens OX=9606 GN=POLR2D PE=1 SV=1"	"11"	"1"	"1"	"1"	"142"	"16.3"	"4.79"	""	"4.17"	""	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf03874"	"5433"	"ENSG00000144231"	"POLR2D"	"hsa:5433; O15514; Q52LT4"	"Pyrimidine metabolism"	"Transcriptional regulation by small RNAs; Viral Messenger RNA Synthesis; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; mRNA Splicing - Major Pathway; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"42"	"0"	"18.7"	"54.7"	"53.4"	"20.9"	"46.6"	"25.1"	"45.1"	"41.2"	"58.0"	"76.7"	"116.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96T60"	"Bifunctional polynucleotide phosphatase/kinase OS=Homo sapiens OX=9606 GN=PNKP PE=1 SV=1"	"3"	"1"	"2"	"1"	"521"	"57.0"	"8.46"	"512.94"	"4.17"	"1"	"1"	"DNA metabolism;other metabolic processes;stress response;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf08645, Pf13671, Pf17913"	"11284"	"ENSG00000039650"	"PNKP"	"hsa:11284; Q96T60; Q9BUL2; Q9P1V2; Q9UKU8; Q9UNF8; Q9UNI0"	"Base excision repair; DNA repair pathways, full network"	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P57060"	"RWD domain-containing protein 2B OS=Homo sapiens OX=9606 GN=RWDD2B PE=1 SV=1"	"5"	"1"	"1"	"1"	"319"	"36.3"	"5.87"	""	"4.15"	""	"1"	""	""	""	"Pf05773, Pf06544"	"10069"	"ENSG00000156253"	"RWDD2B"	"hsa:10069; P57060"	""	""	"0"	"0"	"0.0"	"2.0"	"3.4"	"2.2"	"2.9"	"0.0"	"2.4"	"3.8"	"7.9"	"28.0"	"72.0"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P41214"	"Eukaryotic translation initiation factor 2D OS=Homo sapiens OX=9606 GN=EIF2D PE=1 SV=3"	"5"	"2"	"2"	"2"	"584"	"64.7"	"7.65"	"254.76"	"4.15"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01253, Pf17832"	"1939"	"ENSG00000143486"	"EIF2D"	"hsa:1939; P41214; Q5SY40; Q8IXV3; Q96DG3; Q96TG7; Q9NR27; Q9NSN0; Q9NV18; Q9NZ21"	""	""	"0"	"0"	"28.7"	"59.4"	"58.7"	"23.1"	"46.8"	"23.8"	"58.4"	"32.8"	"60.5"	"97.3"	"133.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NQA3"	"WAS protein family homolog 6 OS=Homo sapiens OX=9606 GN=WASH6P PE=1 SV=3"	"5"	"2"	"3"	"2"	"447"	"48.0"	"5.67"	"694.81"	"4.14"	"2"	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"cytoskeletal activity"	"Pf11945"	""	""	"WASH6P"	"A6NGF1; Q8N305; Q9NQA3"	""	""	"0"	"0"	"34.2"	"56.3"	"76.3"	"27.5"	"54.1"	"40.7"	"100.5"	"48.5"	"119.5"	"111.5"	"175.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00257"	"E3 SUMO-protein ligase CBX4 OS=Homo sapiens OX=9606 GN=CBX4 PE=1 SV=3"	"4"	"1"	"2"	"1"	"560"	"61.3"	"9.36"	"351.41"	"4.12"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00385, Pf17218"	"8535"	"ENSG00000141582"	"CBX4"	"B1PJR7; hsa:8535; O00257; Q6TPI8; Q96C04"	""	"SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Oxidative Stress Induced Senescence; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Regulation of PTEN gene transcription"	"8"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43670"	"BUB3-interacting and GLEBS motif-containing protein ZNF207 OS=Homo sapiens OX=9606 GN=ZNF207 PE=1 SV=1"	"3"	"1"	"2"	"1"	"478"	"50.7"	"9.10"	"460.29"	"4.09"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	""	"7756"	"ENSG00000010244"	"ZNF207"	"A8K6Y6; E1P660; E1P661; E1P662; hsa:7756; O43670; Q53XS9; Q96HW5; Q9BUQ7"	""	""	"0"	"0"	"29.1"	"44.3"	"42.4"	"30.0"	"49.7"	"31.2"	"52.0"	"64.8"	"119.4"	"105.4"	"202.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P54105"	"Methylosome subunit pICln OS=Homo sapiens OX=9606 GN=CLNS1A PE=1 SV=1"	"5"	"1"	"2"	"1"	"237"	"26.2"	"4.11"	"483.52"	"4.08"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	""	"Pf03517"	"1207"	"ENSG00000074201"	"CLNS1A"	"B2RCS9; hsa:1207; P54105; Q0VDK6; Q9NRD2; Q9NRD3"	""	"snRNP Assembly"	"1"	"0"	"48.6"	"202.3"	"157.0"	"23.1"	"119.0"	"39.6"	"84.6"	"74.2"	"101.0"	"112.3"	"205.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95400"	"CD2 antigen cytoplasmic tail-binding protein 2 OS=Homo sapiens OX=9606 GN=CD2BP2 PE=1 SV=1"	"10"	"2"	"4"	"2"	"341"	"37.6"	"4.61"	"1235.60"	"4.07"	"2"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf02213"	"10421"	"ENSG00000169217"	"CD2BP2"	"B2RDX2; hsa:10421; O95400; Q9ULP2"	"mRNA processing; Ciliary landscape"	""	"2"	"0"	"93.6"	"138.1"	"164.2"	"81.3"	"142.4"	"100.3"	"261.8"	"184.2"	"287.4"	"350.9"	"431.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92734"	"Protein TFG OS=Homo sapiens OX=9606 GN=TFG PE=1 SV=2"	"4"	"1"	"2"	"1"	"400"	"43.4"	"5.10"	"491.20"	"4.06"	"1"	"1"	"cell organization and biogenesis;transport"	"cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00564"	"10342"	"ENSG00000114354"	"TFG"	"D3DN49; G5E9V1; hsa:10342; K0J5S8; K0J6K2; Q15656; Q92734; Q969I2"	""	"Signaling by ALK fusions and activated point mutants; COPII-mediated vesicle transport"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9BXS6"	"Nucleolar and spindle-associated protein 1 OS=Homo sapiens OX=9606 GN=NUSAP1 PE=1 SV=1"	"3"	"1"	"2"	"1"	"441"	"49.4"	"9.91"	"384.18"	"4.04"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity"	"Pf16006"	"51203"	"ENSG00000137804"	"NUSAP1"	"B4DDF1; E7ERR5; hsa:51203; J3KN21; Q53GW2; Q8TBT4; Q96E58; Q96FJ1; Q9BXS6; Q9GZM9; Q9NZ85; Q9UI70"	""	""	"0"	"0"	"26.7"	"45.7"	"65.3"	"22.4"	"48.2"	"28.8"	"60.9"	"41.9"	"64.8"	"90.1"	"153.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P26583"	"High mobility group protein B2 OS=Homo sapiens OX=9606 GN=HMGB2 PE=1 SV=2"	"15"	"3"	"4"	"2"	"209"	"24.0"	"7.81"	"1369.35"	"4.01"	"3"	"1"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00505, Pf09011"	"3148"	"ENSG00000164104"	"HMGB2"	"B2R4K8; D3DP37; hsa:3148; P26583; Q5U072"	"Retinoblastoma gene in cancer; Ectoderm differentiation; Ectoderm differentiation"	"Apoptosis induced DNA fragmentation"	"4"	"0"	"31.3"	"48.0"	"67.4"	"21.7"	"55.0"	"33.1"	"200.7"	"163.7"	"208.7"	"239.8"	"360.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04080"	"Cystatin-B OS=Homo sapiens OX=9606 GN=CSTB PE=1 SV=2"	"12"	"1"	"1"	"1"	"98"	"11.1"	"7.56"	""	"4.00"	""	"1"	"other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00031"	"1476"	"ENSG00000160213"	"CSTB"	"hsa:1476; P04080"	""	"Neutrophil degranulation"	"1"	"0"	"30.0"	"101.3"	"90.5"	"21.4"	"69.6"	"35.0"	"50.8"	"46.9"	"90.2"	"169.0"	"433.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31350"	"Ribonucleoside-diphosphate reductase subunit M2 OS=Homo sapiens OX=9606 GN=RRM2 PE=1 SV=1"	"5"	"1"	"2"	"1"	"389"	"44.8"	"5.38"	"303.06"	"4.00"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00268"	"6241"	"ENSG00000171848"	"RRM2"	"B2R9B5; hsa:6241; J3KP43; P31350; Q5WRU7"	"Fluoropyrimidine activity; Retinoblastoma gene in cancer; Hepatitis C and hepatocellular carcinoma; Pyrimidine metabolism; Orexin receptor pathway"	"Transcriptional Regulation by E2F6; Interconversion of nucleotide di- and triphosphates; G1/S-Specific Transcription"	"8"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14497"	"AT-rich interactive domain-containing protein 1A OS=Homo sapiens OX=9606 GN=ARID1A PE=1 SV=3"	"1"	"1"	"1"	"1"	"2285"	"241.9"	"6.70"	""	"3.99"	""	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01388, Pf12031"	"8289"	"ENSG00000117713"	"ARID1A"	"D3DPL1; hsa:8289; O14497; Q53FK9; Q5T0W1; Q5T0W2; Q5T0W3; Q8NFD6; Q96T89; Q9BY33; Q9HBJ5; Q9UPZ1"	"Androgen receptor network in prostate cancer; Pathways affected in adenoid cystic carcinoma; Tumor suppressor activity of SMARCB1; Thermogenesis; Kleefstra syndrome"	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; RMTs methylate histone arginines"	"7"	"0"	"20.3"	"27.6"	"22.0"	"15.1"	"20.7"	"15.2"	"31.5"	"32.8"	"39.8"	"35.6"	"40.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WUR7"	"UPF0235 protein C15orf40 OS=Homo sapiens OX=9606 GN=C15orf40 PE=1 SV=2"	"8"	"1"	"2"	"1"	"153"	"16.3"	"9.83"	"337.33"	"3.99"	"1"	"1"	""	"other cell component"	""	"Pf02594"	"123207"	"ENSG00000169609"	"C15orf40"	"A6NIC9; B2R5E7; F5GX92; F8WD31; G5EA00; hsa:123207; Q8WUR7"	""	""	"0"	"0"	"20.4"	"44.8"	"51.8"	"21.4"	"54.4"	"28.2"	"110.0"	"97.5"	"143.6"	"211.1"	"396.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75368"	"SH3 domain-binding glutamic acid-rich-like protein OS=Homo sapiens OX=9606 GN=SH3BGRL PE=1 SV=1"	"9"	"1"	"2"	"1"	"114"	"12.8"	"5.25"	"423.09"	"3.99"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf04908"	"6451"	"ENSG00000131171"	"SH3BGRL"	"hsa:6451; O75368; Q3SYL1; Q5JT50; Q6FIE8; Q9H0N8"	""	""	"0"	"0"	"43.0"	"354.3"	"332.3"	"24.9"	"293.8"	"83.6"	"110.2"	"74.1"	"102.2"	"110.6"	"226.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96GA3"	"Protein LTV1 homolog OS=Homo sapiens OX=9606 GN=LTV1 PE=1 SV=1"	"3"	"1"	"2"	"1"	"475"	"54.8"	"4.91"	"505.73"	"3.98"	"1"	"1"	"transport;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf04180"	"84946"	"ENSG00000135521"	"LTV1"	"hsa:84946; Q96GA3; Q96JX8"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"16.6"	"37.7"	"32.4"	"16.7"	"37.2"	"18.5"	"30.0"	"21.8"	"40.9"	"39.1"	"42.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NRP0"	"Oligosaccharyltransferase complex subunit OSTC OS=Homo sapiens OX=9606 GN=OSTC PE=1 SV=1"	"8"	"1"	"2"	"1"	"149"	"16.8"	"9.13"	"351.22"	"3.97"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;ER/Golgi"	""	"Pf04756"	"58505"	"ENSG00000198856"	"OSTC"	"A8MYS2; B2R5H1; D6RH22; hsa:58505; Q9NRP0; Q9P075; Q9P1R4"	""	""	"0"	"0"	"17.9"	"82.6"	"69.2"	"15.1"	"71.2"	"20.4"	"36.0"	"29.0"	"40.5"	"52.4"	"85.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UQ13"	"Leucine-rich repeat protein SHOC-2 OS=Homo sapiens OX=9606 GN=SHOC2 PE=1 SV=2"	"2"	"1"	"2"	"1"	"582"	"64.8"	"8.46"	"314.87"	"3.97"	"1"	"1"	"signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf13855"	"8036"	"ENSG00000108061"	"SHOC2"	"A8K9W8; B3KR23; hsa:8036; O76063; Q5VZS8; Q5VZS9; Q9UQ13"	"Ras signaling; 22q11.2 copy number variation syndrome; Autophagy in pancreatic ductal adenocarcinoma"	"RAF activation; SHOC2 M1731 mutant abolishes MRAS complex function; Gain-of-function MRAS complexes activate RAF signaling"	"6"	"0"	"16.8"	"41.3"	"43.1"	"16.8"	"42.9"	"26.4"	"48.1"	"30.3"	"42.2"	"96.4"	"107.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A0A0B4J2D5"	"Glutamine amidotransferase-like class 1 domain-containing protein 3B, mitochondrial OS=Homo sapiens OX=9606 GN=GATD3B PE=1 SV=1"	"4"	"1"	"2"	"1"	"268"	"28.1"	"8.27"	"384.07"	"3.96"	"1"	"1"	""	"mitochondrion"	""	""	"8209"	""	"GATD3B"	"A0A0B4J2D5; A6NFJ6; A6NJY7; hsa:8209; O00650; O00660; O15011; O15012; P30042; P55346; P78474; Q92505; Q92507"	"Gastric cancer network 1"	""	"1"	"0"	"31.3"	"93.0"	"96.3"	"39.7"	"92.8"	"45.3"	"80.7"	"67.4"	"89.5"	"122.6"	"143.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30876"	"DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1"	"1"	"1"	"2"	"1"	"1174"	"133.8"	"6.87"	"460.89"	"3.96"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00562, Pf04560, Pf04561, Pf04563, Pf04565, Pf04566, Pf04567"	"5431"	"ENSG00000047315"	"POLR2B"	"A8K1A8; hsa:5431; P30876; Q8IZ61"	"Pyrimidine metabolism; Eukaryotic transcription initiation"	"Processing of Capped Intron-Containing Pre-mRNA; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; mRNA Splicing - Major Pathway; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"43"	"0"	"26.5"	"32.2"	"38.5"	"21.5"	"34.4"	"24.9"	"31.1"	"17.2"	"30.1"	"32.4"	"37.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99447"	"Ethanolamine-phosphate cytidylyltransferase OS=Homo sapiens OX=9606 GN=PCYT2 PE=1 SV=1"	"3"	"1"	"2"	"1"	"389"	"43.8"	"6.92"	"362.46"	"3.95"	"1"	"1"	"other metabolic processes"	"other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf01467"	"5833"	"ENSG00000185813"	"PCYT2"	"B7Z7A5; B7ZAS0; F5H8B1; hsa:5833; Q6IBM3; Q96G08; Q99447"	"Trans-sulfuration, one-carbon metabolism and related pathways; Kennedy pathway from sphingolipids; Glycerolipids and glycerophospholipids"	"Synthesis of PE"	"4"	"0"	"7.0"	"21.7"	"23.0"	"4.4"	"17.9"	"7.8"	"11.5"	"7.8"	"16.3"	"27.8"	"30.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14139"	"Ubiquitin conjugation factor E4 A OS=Homo sapiens OX=9606 GN=UBE4A PE=1 SV=2"	"1"	"1"	"2"	"1"	"1066"	"122.5"	"5.24"	"432.59"	"3.93"	"1"	"1"	"protein metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf04564, Pf10408"	"9354"	"ENSG00000110344"	"UBE4A"	"B0YJB6; hsa:9354; Q14139; Q2M1H0; Q6P5T4; Q7Z639"	""	"Antigen processing: Ubiquitination & Proteasome degradation"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3Y2"	"Chromatin target of PRMT1 protein OS=Homo sapiens OX=9606 GN=CHTOP PE=1 SV=2"	"5"	"1"	"2"	"1"	"248"	"26.4"	"12.23"	"346.12"	"3.93"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf13865"	"26097"	"ENSG00000160679"	"CHTOP"	"D3DV55; hsa:26097; Q0VAQ8; Q2VPI9; Q5T7Y8; Q5T7Y9; Q5T7Z0; Q6NSM4; Q6PB28; Q8WYT9; Q9BUC5; Q9H034; Q9H2L0; Q9Y3Y2"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"3"	"0"	"31.1"	"33.1"	"45.6"	"27.4"	"58.0"	"34.8"	"59.9"	"36.9"	"52.1"	"61.9"	"74.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A6NJ78"	"12S rRNA N4-methylcytidine (m4C) methyltransferase OS=Homo sapiens OX=9606 GN=METTL15 PE=1 SV=1"	"4"	"1"	"2"	"1"	"407"	"46.1"	"8.62"	"377.63"	"3.93"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf01795"	"196074"	"ENSG00000169519"	"METTL15"	"A6NJ78; A8MRS5; B7WNU2; hsa:196074; Q3MHD3; Q8N601; Q8NBA7"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q06330"	"Recombining binding protein suppressor of hairless OS=Homo sapiens OX=9606 GN=RBPJ PE=1 SV=3"	"3"	"1"	"2"	"1"	"500"	"55.6"	"7.18"	"377.30"	"3.93"	"1"	"1"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09270, Pf09271, Pf20144"	"3516"	"ENSG00000168214"	"RBPJ"	"B4DY22; hsa:3516; Q06330; Q5XKH9; Q6P1N3"	"Neural crest differentiation; Notch signaling; Canonical and non-canonical Notch signaling; PTF1A related regulatory pathway; Epithelial to mesenchymal transition in colorectal cancer; Osteoblast differentiation and related diseases; Genetic causes of porto-sinusoidal vascular disease; 11p11.2 copy number variation syndrome ; Notch signaling pathway"	"Somitogenesis; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; NOTCH1 Intracellular Domain Regulates Transcription; Formation of paraxial mesoderm; Pre-NOTCH Transcription and Translation; Notch-HLH transcription pathway; NOTCH3 Intracellular Domain Regulates Transcription; Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells; NOTCH2 intracellular domain regulates transcription; NOTCH4 Intracellular Domain Regulates Transcription; RUNX3 regulates NOTCH signaling"	"21"	"0"	"6.2"	"9.6"	"8.9"	"5.6"	"12.6"	"3.0"	"15.1"	"19.8"	"26.9"	"48.6"	"121.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09132"	"Signal recognition particle 19 kDa protein OS=Homo sapiens OX=9606 GN=SRP19 PE=1 SV=3"	"10"	"1"	"2"	"1"	"144"	"16.1"	"9.85"	"362.04"	"3.92"	"1"	"1"	"cell organization and biogenesis;transport"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01922"	"6728"	"ENSG00000153037"	"SRP19"	"B2R4E9; D6RCQ5; hsa:6728; P09132; Q05D77; Q96FG6"	""	"SRP-dependent cotranslational protein targeting to membrane"	"1"	"0"	"47.9"	"68.3"	"88.4"	"45.0"	"90.3"	"45.4"	"102.6"	"55.8"	"90.7"	"106.4"	"155.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96AY3"	"Peptidyl-prolyl cis-trans isomerase FKBP10 OS=Homo sapiens OX=9606 GN=FKBP10 PE=1 SV=1"	"2"	"1"	"2"	"1"	"582"	"64.2"	"5.62"	"407.17"	"3.92"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes"	"other membranes;mitochondrion;ER/Golgi"	"other molecular function"	"Pf00254, Pf13202"	"60681"	"ENSG00000141756"	"FKBP10"	"hsa:60681; Q7Z3R4; Q96AY3; Q9H3N3; Q9H6J3; Q9H6N5; Q9UF89"	"Type I collagen synthesis in the context of osteogenesis imperfecta"	""	"1"	"0"	"20.9"	"128.4"	"106.8"	"20.8"	"90.4"	"32.6"	"32.4"	"23.0"	"26.0"	"37.7"	"77.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16527"	"Cysteine and glycine-rich protein 2 OS=Homo sapiens OX=9606 GN=CSRP2 PE=1 SV=3"	"7"	"1"	"2"	"1"	"193"	"20.9"	"8.62"	"461.88"	"3.92"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412"	"1466"	"ENSG00000175183"	"CSRP2"	"hsa:1466; Q16527; Q93030"	"Mesodermal commitment pathway; VEGFA-VEGFR2 signaling; H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity"	""	"3"	"0"	"16.7"	"24.8"	"29.8"	"13.4"	"35.9"	"23.8"	"39.4"	"30.9"	"38.2"	"51.4"	"54.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00267"	"Transcription elongation factor SPT5 OS=Homo sapiens OX=9606 GN=SUPT5H PE=1 SV=1"	"1"	"1"	"2"	"1"	"1087"	"120.9"	"5.06"	"420.02"	"3.91"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00467, Pf03439, Pf11942"	"6829"	"ENSG00000196235"	"SUPT5H"	"hsa:6829; O00267; O43279; Q59G52; Q99639"	"Initiation of transcription and translation elongation at the HIV-1 LTR; mRNA processing"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE"	"20"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NP92"	"39S ribosomal protein S30, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS30 PE=1 SV=2"	"3"	"1"	"2"	"1"	"439"	"50.3"	"7.97"	"436.60"	"3.89"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf07147"	"10884"	"ENSG00000112996"	"MRPS30"	"hsa:10884; Q96I91; Q96Q19; Q9H0P8; Q9NP92; Q9NSF9; Q9NZ76"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"103.3"	"250.2"	"216.1"	"100.4"	"215.2"	"99.7"	"158.7"	"119.4"	"156.5"	"200.8"	"346.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12996"	"Cleavage stimulation factor subunit 3 OS=Homo sapiens OX=9606 GN=CSTF3 PE=1 SV=1"	"3"	"1"	"2"	"1"	"717"	"82.9"	"8.12"	"329.14"	"3.89"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf05843"	"1479"	"ENSG00000176102"	"CSTF3"	"A8K471; D3DR04; E9PB40; hsa:1479; Q12996; Q32P22; Q96FQ8; Q96QD6; Q96QK4"	"mRNA processing"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"5"	"0"	"6.3"	"15.1"	"25.9"	"10.9"	"26.8"	"11.9"	"26.5"	"18.2"	"32.0"	"43.9"	"42.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86WJ1"	"Chromodomain-helicase-DNA-binding protein 1-like OS=Homo sapiens OX=9606 GN=CHD1L PE=1 SV=3"	"2"	"1"	"2"	"1"	"897"	"100.9"	"6.90"	"492.28"	"3.86"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00176, Pf00271"	"9557"	"ENSG00000131778"	"CHD1L"	"A5YM64; B4DDE1; B5MDZ7; hsa:9557; Q53EZ3; Q5VXX7; Q6DD94; Q6PK83; Q86WJ1; Q86XH3; Q96HF7; Q96SP3; Q9BVJ1; Q9NVV8"	"1q21.1 copy number variation syndrome; Nucleotide excision repair in xeroderma pigmentosum"	"Formation of Incision Complex in GG-NER; Dual Incision in GG-NER"	"4"	"0"	"18.9"	"48.1"	"48.3"	"16.7"	"45.2"	"21.9"	"43.5"	"31.1"	"49.9"	"66.2"	"80.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95983"	"Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1"	"12"	"3"	"4"	"3"	"291"	"32.8"	"5.34"	"1068.48"	"3.84"	"3"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01429, Pf14048, Pf16564"	"53615"	"ENSG00000071655"	"MBD3"	"A8K4B7; D6W5Z2; hsa:53615; O95983; Q6PIL9; Q6PJZ9; Q86XF4"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"Potential therapeutics for SARS; Regulation of PTEN gene transcription; HDACs deacetylate histones; RNA Polymerase I Transcription Initiation; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of TP53 Activity through Acetylation"	"7"	"0"	"157.3"	"446.2"	"377.0"	"167.2"	"376.6"	"181.5"	"309.3"	"260.0"	"344.2"	"415.5"	"630.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82932"	"28S ribosomal protein S6, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS6 PE=1 SV=3"	"10"	"1"	"3"	"1"	"125"	"14.2"	"9.26"	"732.50"	"3.84"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf01250"	"64968"	"ENSG00000243927"	"MRPS6"	"B2R573; hsa:64968; P82932; Q96Q64; Q9BSK8; Q9BW89"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"59.4"	"208.4"	"163.9"	"84.0"	"130.2"	"90.5"	"86.1"	"66.1"	"72.9"	"92.3"	"156.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6SPF0"	"Atherin OS=Homo sapiens OX=9606 GN=SAMD1 PE=1 SV=1"	"4"	"1"	"1"	"1"	"538"	"56.0"	"7.58"	""	"3.84"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"other molecular function"	"Pf00536"	"90378"	"ENSG00000288488"	"SAMD1"	"hsa:90378; Q6P0R3; Q6PIS7; Q6SPF0; Q96IM4"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86UP2"	"Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1"	"2"	"3"	"4"	"3"	"1357"	"156.2"	"5.64"	"960.90"	"3.83"	"3"	"1"	"transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi"	"cytoskeletal activity"	"Pf05104"	"3895"	"ENSG00000126777"	"KTN1"	"B4DZ88; hsa:3895; Q13999; Q14707; Q15387; Q17RZ5; Q5GGW3; Q86UP2; Q86W57"	"Glucocorticoid receptor pathway; Nuclear receptors meta-pathway"	"RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RND2 GTPase cycle; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; RND3 GTPase cycle; RHOG GTPase cycle; RHO GTPases activate KTN1"	"11"	"0"	"61.3"	"214.2"	"202.5"	"68.4"	"175.1"	"83.7"	"153.9"	"109.3"	"197.8"	"242.3"	"419.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95163"	"Elongator complex protein 1 OS=Homo sapiens OX=9606 GN=ELP1 PE=1 SV=3"	"1"	"1"	"2"	"1"	"1332"	"150.2"	"5.94"	"488.52"	"3.83"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04762"	"8518"	"ENSG00000070061"	"ELP1"	"hsa:8518; O95163; Q5JSV2; Q9H327; Q9UG87"	""	"HATs acetylate histones"	"1"	"0"	"35.9"	"51.0"	"50.0"	"28.5"	"54.8"	"32.3"	"41.8"	"32.5"	"52.9"	"63.1"	"72.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y676"	"28S ribosomal protein S18b, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS18B PE=1 SV=1"	"9"	"1"	"1"	"1"	"258"	"29.4"	"9.38"	""	"3.82"	""	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01084"	"28973"	"ENSG00000203624; ENSG00000204568; ENSG00000223775; ENSG00000226111; ENSG00000227420; ENSG00000229861; ENSG00000233813"	"MRPS18B"	"A6NDQ0; hsa:28973; Q659G4; Q9BS27; Q9Y676"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"11.5"	"28.8"	"30.9"	"12.4"	"26.7"	"11.7"	"29.9"	"24.8"	"34.3"	"39.4"	"50.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13625"	"Apoptosis-stimulating of p53 protein 2 OS=Homo sapiens OX=9606 GN=TP53BP2 PE=1 SV=2"	"2"	"1"	"1"	"1"	"1128"	"125.5"	"6.07"	""	"3.81"	""	"1"	"cell cycle OR cell proliferation;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00018, Pf00023"	"7159"	"ENSG00000143514"	"TP53BP2"	"B4DG66; hsa:7159; Q12892; Q13625; Q86X75; Q96KQ3"	""	"TP53 Regulates Transcription of Death Receptors and Ligands; Activation of PUMA and translocation to mitochondria; TP53 Regulates Transcription of Genes Involved in Cytochrome C Release; TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain; Regulation of TP53 Activity through Association with Co-factors"	"5"	"0"	"8.9"	"20.5"	"20.4"	"12.0"	"23.6"	"8.2"	"23.7"	"14.9"	"23.5"	"28.1"	"39.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00203"	"AP-3 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP3B1 PE=1 SV=3"	"2"	"2"	"3"	"2"	"1094"	"121.2"	"6.04"	"382.77"	"3.81"	"1"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01602, Pf14796, Pf14797"	"8546"	"ENSG00000132842"	"AP3B1"	"E5RJ68; hsa:8546; O00203; O00580; Q7Z393; Q9HD66"	""	"Golgi Associated Vesicle Biogenesis; Signaling by BRAF and RAF1 fusions"	"2"	"0"	"10.5"	"21.5"	"25.4"	"3.4"	"21.4"	"7.0"	"26.7"	"20.4"	"43.4"	"52.0"	"86.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15143"	"Actin-related protein 2/3 complex subunit 1B OS=Homo sapiens OX=9606 GN=ARPC1B PE=1 SV=3"	"4"	"1"	"2"	"1"	"372"	"40.9"	"8.35"	"490.53"	"3.80"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400"	"10095"	"ENSG00000130429"	"ARPC1B"	"hsa:10095; O15143; Q9BU00"	"Pathogenic Escherichia coli infection; Microglia pathogen phagocytosis pathway"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; EPHB-mediated forward signaling"	"6"	"0"	"29.5"	"31.3"	"46.6"	"29.6"	"46.2"	"28.2"	"171.0"	"189.0"	"223.9"	"424.3"	"924.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NTK5"	"Obg-like ATPase 1 OS=Homo sapiens OX=9606 GN=OLA1 PE=1 SV=2"	"3"	"1"	"2"	"1"	"396"	"44.7"	"7.81"	"278.52"	"3.79"	"1"	"1"	"other metabolic processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cell component"	"translation activity;other molecular function"	"Pf01926, Pf06071"	"29789"	"ENSG00000138430"	"OLA1"	"D7EHM2; hsa:29789; Q5BJD7; Q8NCI8; Q96CU1; Q96SV2; Q9NTK5; Q9P1D3; Q9UNY9; Q9Y6G4"	""	"Platelet degranulation"	"1"	"0"	"34.7"	"128.2"	"135.0"	"28.0"	"109.8"	"39.6"	"68.3"	"56.1"	"60.5"	"80.4"	"153.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q4KMP7"	"TBC1 domain family member 10B OS=Homo sapiens OX=9606 GN=TBC1D10B PE=1 SV=3"	"3"	"1"	"3"	"1"	"808"	"87.1"	"9.19"	""	"3.79"	""	"1"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol"	"enzyme regulator activity"	"Pf00566"	"26000"	"ENSG00000169221"	"TBC1D10B"	"B9A6L0; hsa:26000; Q4KMP7; Q6IN54; Q6P530; Q71RG7; Q86VC5; Q9H8Z2; Q9NUN6; Q9UFP2"	""	"TBC/RABGAPs"	"1"	"0"	"4.3"	"7.6"	"28.6"	"0.0"	"10.5"	"3.5"	"8.3"	"9.7"	"10.5"	"13.3"	"18.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BU23"	"Lipase maturation factor 2 OS=Homo sapiens OX=9606 GN=LMF2 PE=1 SV=2"	"3"	"1"	"1"	"1"	"707"	"79.6"	"10.10"	""	"3.78"	""	"1"	"protein metabolism;other metabolic processes"	"other membranes;ER/Golgi"	""	"Pf06762"	"91289"	"ENSG00000100258"	"LMF2"	"A6NEZ0; hsa:91289; Q13392; Q6ZNR2; Q8WU74; Q96C62; Q9BU23"	""	"Assembly of active LPL and LIPC lipase complexes"	"1"	"0"	"5.0"	"26.4"	"14.0"	"7.6"	"12.8"	"14.1"	"17.1"	"20.6"	"19.3"	"15.7"	"20.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13480"	"GRB2-associated-binding protein 1 OS=Homo sapiens OX=9606 GN=GAB1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"694"	"76.6"	"5.96"	"465.66"	"3.78"	"1"	"1"	"developmental processes;signal transduction;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00169"	"2549"	"ENSG00000109458"	"GAB1"	"A8K152; hsa:2549; Q13480; Q4W5G2; Q6P1W2"	"Glioblastoma signaling pathways; Androgen receptor network in prostate cancer; B cell receptor signaling pathway; Alpha 6 beta 4 signaling pathway; Hepatocyte growth factor receptor signaling; IL6 signaling pathway; BDNF-TrkB signaling; VEGFA-VEGFR2 signaling; Embryonic stem cell pluripotency pathways; Ras signaling; EGF/EGFR signaling pathway; Fragile X syndrome; Head and neck squamous cell carcinoma; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; GDNF signaling; A network map of Macrophage-stimulating protein (MSP) signaling; ErbB signaling pathway"	"RET signaling; PIP3 activates AKT signaling; Constitutive Signaling by Aberrant PI3K in Cancer; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; MET activates RAP1 and RAC1; Erythropoietin activates Phosphoinositide-3-kinase (PI3K); PI3K Cascade; PI3K events in ERBB2 signaling; Signaling by ERBB2 KD Mutants; GAB1 signalosome; Signaling by FGFR1 in disease; PI-3K cascade:FGFR1; PI-3K cascade:FGFR2; Signaling by FGFR2 in disease; PI-3K cascade:FGFR3; PI-3K cascade:FGFR4; Signaling by FGFR3 in disease; Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; Constitutive Signaling by EGFRvIII; Signaling by ERBB2 ECD mutants; Signaling by FGFR4 in disease; MET activates PI3K/AKT signaling; MET activates PTPN11; MET receptor recycling; Activated NTRK2 signals through PI3K"	"43"	"0"	"9.5"	"7.4"	"8.7"	"6.3"	"6.2"	"7.1"	"14.3"	"16.6"	"30.4"	"35.7"	"57.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BV20"	"Methylthioribose-1-phosphate isomerase OS=Homo sapiens OX=9606 GN=MRI1 PE=1 SV=1"	"4"	"1"	"2"	"1"	"369"	"39.1"	"6.30"	"432.92"	"3.78"	"1"	"1"	"other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01008"	"84245"	"ENSG00000037757"	"MRI1"	"hsa:84245; Q8NDC9; Q9BV20"	"Methionine de novo and salvage pathway"	"Methionine salvage pathway"	"2"	"0"	"11.6"	"82.1"	"61.0"	"3.4"	"56.4"	"16.2"	"22.3"	"16.4"	"19.3"	"23.0"	"40.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43237"	"Cytoplasmic dynein 1 light intermediate chain 2 OS=Homo sapiens OX=9606 GN=DYNC1LI2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"492"	"54.1"	"6.38"	"322.60"	"3.76"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf05783"	"1783"	"ENSG00000135720"	"DYNC1LI2"	"A8K6V1; B4DZP4; hsa:1783; O43237; Q8TAT3"	"Intraflagellar transport proteins binding to dynein"	"COPI-mediated anterograde transport; Separation of Sister Chromatids; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; RHO GTPases Activate Formins; COPI-independent Golgi-to-ER retrograde traffic; HCMV Early Events; Aggrephagy; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"13"	"0"	"9.8"	"16.8"	"27.4"	"5.1"	"23.3"	"5.2"	"22.3"	"11.7"	"22.9"	"22.0"	"35.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00429"	"Dynamin-1-like protein OS=Homo sapiens OX=9606 GN=DNM1L PE=1 SV=2"	"2"	"1"	"2"	"1"	"736"	"81.8"	"6.81"	"435.31"	"3.76"	"1"	"1"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00350, Pf01031, Pf02212"	"10059"	"ENSG00000087470"	"DNM1L"	"A8K4X9; B4DGC9; B4DSU8; G8JLD5; hsa:10059; J3KPI2; O00429; O14541; O60709; Q59GN9; Q7L6B3; Q8TBT7; Q9BWM1; Q9Y5J2"	"Synaptic vesicle pathway; CAMKK2 pathway; 10q11.21q11.23 copy number variation syndrome"	"Apoptotic execution phase"	"4"	"0"	"14.2"	"53.9"	"43.9"	"11.5"	"35.8"	"11.6"	"20.5"	"24.5"	"38.7"	"43.4"	"61.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BXJ9"	"N-alpha-acetyltransferase 15, NatA auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA15 PE=1 SV=1"	"1"	"1"	"2"	"1"	"866"	"101.2"	"7.42"	"419.76"	"3.76"	"1"	"1"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity"	"Pf12569, Pf13181"	"80155"	"ENSG00000164134"	"NAA15"	"D3DNY6; hsa:80155; Q52LG9; Q8IWH4; Q8NEV2; Q9BXJ9; Q9H8P6"	""	""	"0"	"0"	"10.8"	"13.6"	"11.7"	"8.3"	"22.6"	"13.0"	"26.1"	"20.6"	"22.1"	"30.3"	"50.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BXK1"	"Krueppel-like factor 16 OS=Homo sapiens OX=9606 GN=KLF16 PE=1 SV=1"	"7"	"1"	"2"	"1"	"252"	"25.4"	"9.88"	"419.19"	"3.76"	"1"	"1"	"RNA metabolism OR transcription;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00096"	"83855"	"ENSG00000129911"	"KLF16"	"hsa:83855; Q9BXK1"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35080"	"Profilin-2 OS=Homo sapiens OX=9606 GN=PFN2 PE=1 SV=3"	"10"	"1"	"2"	"1"	"140"	"15.0"	"6.99"	"366.63"	"3.76"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00235"	"5217"	"ENSG00000070087"	"PFN2"	"B2R4C8; D3DNI4; hsa:5217; P35080; Q4VBQ4; Q8WVF9; Q9HBK2"	"Physico-chemical features and toxicity-associated pathways"	"RHO GTPases Activate Formins; Signaling by ROBO receptors"	"3"	"0"	"29.6"	"56.5"	"52.8"	"23.7"	"73.3"	"34.2"	"47.7"	"41.8"	"61.7"	"91.1"	"136.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N3U4"	"Cohesin subunit SA-2 OS=Homo sapiens OX=9606 GN=STAG2 PE=1 SV=3"	"1"	"1"	"2"	"1"	"1231"	"141.2"	"5.43"	"413.65"	"3.75"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf08514"	"10735"	"ENSG00000101972"	"STAG2"	"B1AMT5; D3DTF5; hsa:10735; O00540; Q5JTI6; Q68DE9; Q8N3U4; Q9H1N8"	"Cell cycle; Cohesin complex - Cornelia de Lange syndrome"	"Separation of Sister Chromatids; Meiotic synapsis; Estrogen-dependent gene expression; Resolution of Sister Chromatid Cohesion; SUMOylation of DNA damage response and repair proteins; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"9"	"0"	"6.7"	"13.0"	"15.9"	"5.2"	"16.5"	"12.9"	"12.7"	"6.8"	"10.5"	"14.9"	"18.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92793"	"CREB-binding protein OS=Homo sapiens OX=9606 GN=CREBBP PE=1 SV=3"	"1"	"1"	"2"	"1"	"2442"	"265.2"	"8.53"	"345.45"	"3.75"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00439, Pf00569, Pf02135, Pf02172, Pf06001, Pf08214, Pf09030"	"1387"	"ENSG00000005339"	"CREBBP"	"D3DUC9; hsa:1387; O00147; Q16376; Q4LE28; Q92793"	"Androgen receptor signaling pathway; Angiogenesis; TNF-alpha signaling pathway; Notch signaling; Initiation of transcription and translation elongation at the HIV-1 LTR; IL6 signaling pathway; Pathways affected in adenoid cystic carcinoma; Hematopoietic stem cell gene regulation by GABP alpha/beta complex; VEGFA-VEGFR2 signaling; Wnt signaling pathway and pluripotency; Clear cell renal cell carcinoma pathways; Ebola virus infection in host; Type 2 papillary renal cell carcinoma; Ciliary landscape; Hepatitis B infection; Male infertility; TGF-beta receptor signaling in skeletal dysplasias; Overlap between signal transduction pathways contributing to LMNA laminopathies; 15q13.3 copy number variation syndrome; Urotensin-II-mediated signaling pathway; TGF-beta receptor signaling; Sudden infant death syndrome (SIDS) susceptibility pathways"	"SUMOylation of transcription cofactors; Formation of paraxial mesoderm; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Pre-NOTCH Transcription and Translation; NOTCH1 Intracellular Domain Regulates Transcription; Notch-HLH transcription pathway; NOTCH3 Intracellular Domain Regulates Transcription; Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells; NOTCH4 Intracellular Domain Regulates Transcription; RUNX3 regulates NOTCH signaling; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Activation of the TFAP2 (AP-2) family of transcription factors; PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; NPAS4 regulates expression of target genes; Heme signaling; Formation of the beta-catenin:TCF transactivating complex; BMAL1:CLOCK,NPAS2 activates circadian gene expression; Transcriptional activation of mitochondrial biogenesis; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Cytoprotection by HMOX1; Activation of gene expression by SREBF (SREBP); NFE2L2 regulating anti-oxidant/detoxification enzymes; HATs acetylate histones; TP53 Regulates Transcription of Genes Involved in Cytochrome C Release; Nuclear events mediated by NFE2L2; NFE2L2 regulates pentose phosphate pathway genes; FOXO-mediated transcription of cell death genes; Regulation of FOXO transcriptional activity by acetylation; RORA activates gene expression; Attenuation phase; CD209 (DC-SIGN) signaling; TRAF3-dependent IRF activation pathway; TRAF6 mediated IRF7 activation; Regulation of gene expression by Hypoxia-inducible Factor; RUNX1 regulates transcription of genes involved in differentiation of myeloid cells; LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production"	"63"	"0"	"5.9"	"26.8"	"22.2"	"8.3"	"19.6"	"9.7"	"37.2"	"18.2"	"31.7"	"39.6"	"57.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P36551"	"Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3"	"4"	"1"	"2"	"1"	"454"	"50.1"	"8.25"	"276.87"	"3.73"	"1"	"1"	"other metabolic processes;other biological processes"	"other membranes;cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf01218"	"1371"	"ENSG00000080819"	"CPOX"	"A8K275; B4DSD5; hsa:1371; P36551; Q14060; Q53F08; Q8IZ45; Q96AF3"	"Hemesynthesis defects and porphyrias; Heme biosynthesis"	"Heme biosynthesis"	"3"	"0"	"4.4"	"38.4"	"27.2"	"4.2"	"22.7"	"7.3"	"8.4"	"7.5"	"12.8"	"19.1"	"51.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35250"	"Replication factor C subunit 2 OS=Homo sapiens OX=9606 GN=RFC2 PE=1 SV=3"	"5"	"1"	"2"	"1"	"354"	"39.1"	"6.44"	"431.01"	"3.71"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00004, Pf08542"	"5982"	"ENSG00000049541"	"RFC2"	"B5BU07; D3DXG3; hsa:5982; P32846; P35250; Q9BU93"	"DNA replication; Nucleotide excision repair; 7q11.23 copy number variation syndrome; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"Regulation of TP53 Activity through Phosphorylation; Activation of ATR in response to replication stress; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Polymerase switching on the C-strand of the telomere; Polymerase switching; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER"	"27"	"0"	"19.2"	"43.1"	"48.7"	"23.0"	"39.7"	"28.5"	"39.9"	"32.6"	"41.5"	"70.0"	"103.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P68400"	"Casein kinase II subunit alpha OS=Homo sapiens OX=9606 GN=CSNK2A1 PE=1 SV=1"	"5"	"1"	"2"	"1"	"391"	"45.1"	"7.74"	"355.26"	"3.70"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"1457"	"ENSG00000101266"	"CSNK2A1"	"B4DYS6; D3DVV8; hsa:1457; P19138; P20426; P68400; Q14013; Q5U065"	"Alzheimer's disease and miRNA effects; TNF-alpha signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; lncRNA in canonical Wnt signaling and colorectal cancer; Breast cancer pathway; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Translation inhibitors in chronically activated PDGFRA cells; Measles virus infection; Pleural mesothelioma; Alzheimer's disease"	"Regulation of PTEN stability and activity; KEAP1-NFE2L2 pathway; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Regulation of TP53 Activity through Phosphorylation; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; WNT mediated activation of DVL; Signal transduction by L1; Receptor Mediated Mitophagy; Condensation of Prometaphase Chromosomes; Synthesis of PC"	"21"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13685"	"Angio-associated migratory cell protein OS=Homo sapiens OX=9606 GN=AAMP PE=1 SV=2"	"3"	"1"	"1"	"1"	"434"	"46.7"	"4.42"	""	"3.70"	""	"1"	"developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00400"	"14"	"ENSG00000127837"	"AAMP"	"hsa:14; Q13685; Q8WUJ9; Q96H92"	"Nucleotide-binding oligomerization domain (NOD) pathway"	"Thromboxane signalling through TP receptor; Signaling by EGFR; NOD1/2 Signaling Pathway; Signaling by VEGF"	"5"	"0"	"7.5"	"12.2"	"20.3"	"5.9"	"9.2"	"8.5"	"10.9"	"4.8"	"13.1"	"9.5"	"16.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z7A4"	"PX domain-containing protein kinase-like protein OS=Homo sapiens OX=9606 GN=PXK PE=1 SV=1"	"3"	"1"	"2"	"1"	"578"	"64.9"	"9.35"	"332.11"	"3.70"	"1"	"1"	"stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00787, Pf02205"	"54899"	"ENSG00000168297"	"PXK"	"hsa:54899; Q3BCH4; Q3BCH5; Q3BCH6; Q3BDW1; Q45L83; Q59EX3; Q6PK17; Q6ZN39; Q7Z7A4; Q96CA3; Q96R07; Q9NXB8"	""	""	"0"	"0"	"5.5"	"16.2"	"12.8"	"7.0"	"10.3"	"8.3"	"14.1"	"8.6"	"15.7"	"24.1"	"28.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A6NMY6"	"Putative annexin A2-like protein OS=Homo sapiens OX=9606 GN=ANXA2P2 PE=5 SV=2"	"4"	"1"	"2"	"1"	"339"	"38.6"	"6.95"	"397.09"	"3.67"	"1"	"1"	"transport"	"non-structural extracellular;extracellular matrix;plasma membrane;other membranes;nucleus;other cell component"	"transporter activity;enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00191"	""	""	"ANXA2P2"	"A6NMY6"	""	""	"0"	"0"	"19.6"	"42.6"	"129.2"	"32.3"	"51.1"	"43.1"	"94.2"	"82.8"	"100.7"	"145.1"	"184.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00116"	"Alkyldihydroxyacetonephosphate synthase, peroxisomal OS=Homo sapiens OX=9606 GN=AGPS PE=1 SV=1"	"4"	"2"	"4"	"2"	"658"	"72.9"	"7.34"	"658.83"	"3.66"	"2"	"2"	"other metabolic processes"	"cytosol;other cytoplasmic organelle"	"other molecular function"	"Pf01565, Pf02913"	"8540"	"ENSG00000018510"	"AGPS"	"A5D8U9; hsa:8540; O00116; Q2TU35"	"Triacylglyceride synthesis"	"Plasmalogen biosynthesis; TYSND1 cleaves peroxisomal proteins"	"4"	"0"	"39.9"	"119.2"	"106.1"	"42.3"	"115.3"	"57.9"	"66.1"	"47.8"	"81.9"	"122.7"	"214.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UIM3"	"FK506-binding protein-like OS=Homo sapiens OX=9606 GN=FKBPL PE=1 SV=1"	"3"	"1"	"2"	"1"	"349"	"38.2"	"5.50"	"453.72"	"3.66"	"1"	"1"	"other biological processes"	"non-structural extracellular;cytosol"	""	"Pf00515"	"63943"	"ENSG00000204315; ENSG00000223666; ENSG00000224200; ENSG00000230907"	"FKBPL"	"A8K5V3; B0UYX8; hsa:63943; Q9H5G3; Q9UIM3"	""	"The role of GTSE1 in G2/M progression after G2 checkpoint"	"1"	"0"	"4.0"	"13.5"	"11.0"	"5.2"	"11.5"	"5.0"	"12.7"	"18.5"	"17.4"	"22.1"	"26.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P54578"	"Ubiquitin carboxyl-terminal hydrolase 14 OS=Homo sapiens OX=9606 GN=USP14 PE=1 SV=3"	"3"	"1"	"2"	"1"	"494"	"56.0"	"5.30"	"308.43"	"3.66"	"1"	"1"	"cell-cell signaling;protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00443"	"9097"	"ENSG00000101557"	"USP14"	"B7Z4N8; hsa:9097; J3QRZ5; P54578; Q53XY5"	""	"Ub-specific processing proteases; Regulation of NF-kappa B signaling"	"2"	"0"	"24.3"	"50.5"	"57.7"	"20.5"	"54.5"	"29.8"	"32.1"	"23.6"	"33.9"	"38.1"	"59.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62877"	"E3 ubiquitin-protein ligase RBX1 OS=Homo sapiens OX=9606 GN=RBX1 PE=1 SV=1"	"13"	"1"	"2"	"1"	"108"	"12.3"	"6.96"	"457.23"	"3.66"	"1"	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf12678"	"9978"	"ENSG00000100387"	"RBX1"	"B2RDY1; hsa:9978; P62877; Q8N6Z8; Q9D1S2; Q9WUK9; Q9Y254"	"Cell cycle; Dual hijack model of Vif in HIV infection; Type 2 papillary renal cell carcinoma; NRF2-ARE regulation; Hippo-Merlin signaling dysregulation; 22q11.2 copy number variation syndrome; Nucleotide excision repair; Hijack of ubiquitination by SARS-CoV-2; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; 1p36 copy number variation syndrome"	"Potential therapeutics for SARS; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; Dual Incision in GG-NER; Regulation of expression of SLITs and ROBOs; Antigen processing: Ubiquitination & Proteasome degradation; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Degradation of DVL; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; Orc1 removal from chromatin; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Neddylation; Interleukin-1 signaling; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Regulation of BACH1 activity; NOTCH1 Intracellular Domain Regulates Transcription; Formation of TC-NER Pre-Incision Complex; Prolactin receptor signaling; DNA Damage Recognition in GG-NER; Nuclear events stimulated by ALK signaling in cancer; Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling"	"46"	"0"	"47.0"	"96.3"	"97.0"	"30.7"	"121.0"	"45.3"	"100.9"	"81.1"	"125.8"	"166.3"	"276.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75947"	"ATP synthase subunit d, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PD PE=1 SV=3"	"11"	"1"	"2"	"1"	"161"	"18.5"	"5.30"	"353.47"	"3.64"	"1"	"1"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf05873"	"10476"	"ENSG00000167863"	"ATP5PD"	"B2R5L6; hsa:10476; O75947; Q9H3J4"	"Electron transport chain: OXPHOS system in mitochondria; Oxidative phosphorylation"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"4"	"0"	"14.8"	"52.8"	"44.7"	"13.7"	"43.6"	"21.5"	"35.2"	"37.3"	"37.4"	"53.0"	"78.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UQN3"	"Charged multivesicular body protein 2b OS=Homo sapiens OX=9606 GN=CHMP2B PE=1 SV=1"	"5"	"1"	"2"	"1"	"213"	"23.9"	"8.76"	"370.85"	"3.64"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf03357"	"25978"	"ENSG00000083937"	"CHMP2B"	"B4DJG8; hsa:25978; Q53HC7; Q9UQN3; Q9Y4U6"	""	"Budding and maturation of HIV virion; Endosomal Sorting Complex Required For Transport (ESCRT); HCMV Late Events; Sealing of the nuclear envelope (NE) by ESCRT-III; Late endosomal microautophagy; Macroautophagy; Pyroptosis; Translation of Replicase and Assembly of the Replication Transcription Complex; Translation of Replicase and Assembly of the Replication Transcription Complex"	"9"	"0"	"99.7"	"141.1"	"130.3"	"85.9"	"148.0"	"82.5"	"195.9"	"165.0"	"198.9"	"244.0"	"311.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15831"	"Serine/threonine-protein kinase STK11 OS=Homo sapiens OX=9606 GN=STK11 PE=1 SV=1"	"4"	"1"	"2"	"1"	"433"	"48.6"	"7.43"	"390.67"	"3.63"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069"	"6794"	"ENSG00000118046"	"STK11"	"B2RBX7; E7EW76; hsa:6794; Q15831"	"AMP-activated protein kinase signaling; mir-124 predicted interactions with cell cycle and differentiation ; ATM signaling in development and disease ; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Head and neck squamous cell carcinoma; Female steroid hormones in cardiomyocyte energy metabolism"	"Regulation of TP53 Activity through Phosphorylation; Energy dependent regulation of mTOR by LKB1-AMPK; FOXO-mediated transcription of cell death genes; AMPK inhibits chREBP transcriptional activation activity"	"12"	"0"	"3.2"	"12.0"	"10.9"	"6.3"	"12.7"	"9.1"	"11.6"	"19.2"	"25.5"	"36.5"	"50.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P0DI83"	"Ras-related protein Rab-34, isoform NARR OS=Homo sapiens OX=9606 GN=RAB34 PE=1 SV=1"	"9"	"1"	"2"	"1"	"198"	"21.1"	"12.16"	"559.97"	"3.63"	"1"	"1"	""	"nucleus"	""	""	"83871"	"ENSG00000109113"	"RAB34"	"P0DI83"	""	""	"0"	"0"	"5.3"	"13.6"	"12.7"	"8.7"	"10.3"	"5.8"	"39.0"	"24.8"	"39.5"	"34.4"	"49.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P48556"	"26S proteasome non-ATPase regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMD8 PE=1 SV=2"	"4"	"1"	"2"	"1"	"350"	"39.6"	"9.70"	"391.38"	"3.62"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf10075"	"5714"	"ENSG00000099341"	"PSMD8"	"B4DX18; hsa:5714; P48556; Q6P1L7"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Ciliary landscape; Alzheimer's disease"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Regulation of RAS by GAPs; Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Regulation of expression of SLITs and ROBOs; Degradation of beta-catenin by the destruction complex; Ub-specific processing proteases; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"64"	"0"	"13.8"	"32.2"	"28.2"	"10.7"	"21.8"	"20.4"	"22.2"	"16.7"	"19.8"	"26.9"	"34.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NEB9"	"Phosphatidylinositol 3-kinase catalytic subunit type 3 OS=Homo sapiens OX=9606 GN=PIK3C3 PE=1 SV=1"	"2"	"1"	"2"	"1"	"887"	"101.5"	"6.81"	"456.46"	"3.62"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf00454, Pf00613, Pf00792"	"5289"	"ENSG00000078142"	"PIK3C3"	"hsa:5289; Q15134; Q8NEB9"	"AMP-activated protein kinase signaling; Alzheimer's disease and miRNA effects; Angiopoietin-like protein 8 regulatory pathway; Microglia pathogen phagocytosis pathway; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Osteoblast differentiation and related diseases; Insulin signaling; Autophagy; Regulation of actin cytoskeleton; Alzheimer's disease; Clock-controlled autophagy in bone metabolism; DNA damage response (only ATM dependent)"	"SARS-CoV-2 activates/modulates innate and adaptive immune responses; Synthesis of PIPs at the Golgi membrane; Synthesis of PIPs at the early endosome membrane; Synthesis of PIPs at the late endosome membrane; PI3K Cascade; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Macroautophagy; Translation of Replicase and Assembly of the Replication Transcription Complex; Translation of Replicase and Assembly of the Replication Transcription Complex; RHO GTPases Activate NADPH Oxidases; Toll Like Receptor 9 (TLR9) Cascade"	"23"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96MW1"	"Coiled-coil domain-containing protein 43 OS=Homo sapiens OX=9606 GN=CCDC43 PE=1 SV=2"	"7"	"1"	"2"	"1"	"224"	"25.2"	"4.92"	"271.68"	"3.61"	"1"	"1"	""	"cytosol"	""	""	"124808"	"ENSG00000180329"	"CCDC43"	"C9JVK9; hsa:124808; Q96MW1"	""	""	"0"	"0"	"4.6"	"8.6"	"17.4"	"4.0"	"16.2"	"9.5"	"8.9"	"5.5"	"18.7"	"22.2"	"20.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13496"	"Myotubularin OS=Homo sapiens OX=9606 GN=MTM1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"603"	"69.9"	"8.18"	"283.78"	"3.60"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf02893, Pf06602"	"4534"	"ENSG00000171100"	"MTM1"	"A6NDB1; B7Z491; F2Z330; hsa:4534; Q13496; Q8NEL1"	""	"Synthesis of PIPs at the plasma membrane; Synthesis of PIPs at the early endosome membrane; Synthesis of PIPs at the late endosome membrane"	"3"	"0"	"9.7"	"19.7"	"18.6"	"11.9"	"18.4"	"11.6"	"29.1"	"26.3"	"48.8"	"74.6"	"99.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14795"	"Protein unc-13 homolog B OS=Homo sapiens OX=9606 GN=UNC13B PE=1 SV=2"	"1"	"1"	"2"	"1"	"1591"	"180.6"	"5.99"	"344.97"	"3.60"	"1"	"1"	"cell-cell signaling;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00130, Pf00168, Pf06292"	"10497"	"ENSG00000198722"	"UNC13B"	"hsa:10497; O14795; Q2NKJ5; Q5VYM8"	"Synaptic vesicle pathway; 16p11.2 proximal deletion syndrome; Monoamine transport"	"Glutamate Neurotransmitter Release Cycle; Serotonin Neurotransmitter Release Cycle; Norepinephrine Neurotransmitter Release Cycle; Dopamine Neurotransmitter Release Cycle; Acetylcholine Neurotransmitter Release Cycle"	"8"	"0"	"7.8"	"21.3"	"18.8"	"7.6"	"17.3"	"9.2"	"15.6"	"19.3"	"34.2"	"51.1"	"90.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BYD2"	"39S ribosomal protein L9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL9 PE=1 SV=2"	"6"	"1"	"2"	"1"	"267"	"30.2"	"10.08"	"424.85"	"3.59"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf01281"	"65005"	"ENSG00000143436"	"MRPL9"	"B2RD99; hsa:65005; Q5SZR2; Q9BSW8; Q9BYD2"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"19.1"	"61.1"	"56.1"	"20.7"	"46.5"	"19.9"	"36.3"	"31.3"	"52.3"	"58.3"	"95.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15067"	"Phosphoribosylformylglycinamidine synthase OS=Homo sapiens OX=9606 GN=PFAS PE=1 SV=4"	"1"	"1"	"2"	"1"	"1338"	"144.6"	"5.76"	"300.18"	"3.59"	"1"	"1"	"other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf02769, Pf13507, Pf18072, Pf18076"	"5198"	"ENSG00000178921"	"PFAS"	"A6H8V8; hsa:5198; O15067"	""	"Purine ribonucleoside monophosphate biosynthesis"	"1"	"0"	"51.9"	"154.6"	"142.7"	"37.2"	"134.6"	"52.8"	"96.7"	"96.0"	"159.8"	"209.1"	"265.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75717"	"WD repeat and HMG-box DNA-binding protein 1 OS=Homo sapiens OX=9606 GN=WDHD1 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1129"	"125.9"	"5.62"	"469.22"	"3.58"	"1"	"1"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400, Pf12341, Pf12894"	"11169"	"ENSG00000198554"	"WDHD1"	"C9JW18; F6W0U7; hsa:11169; O75717"	"Mesodermal commitment pathway"	""	"1"	"0"	"21.1"	"37.8"	"41.0"	"19.4"	"42.9"	"25.2"	"46.3"	"31.8"	"51.9"	"60.9"	"87.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96ST2"	"Protein IWS1 homolog OS=Homo sapiens OX=9606 GN=IWS1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"819"	"91.9"	"4.69"	"384.91"	"3.58"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus"	""	"Pf08711"	"55677"	"ENSG00000163166"	"IWS1"	"hsa:55677; Q2TB65; Q6P157; Q8N3E8; Q96MI7; Q96ST2; Q9NV97; Q9NWH8"	""	"Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events"	"3"	"0"	"5.3"	"15.7"	"12.8"	"2.6"	"12.1"	"4.8"	"12.9"	"8.5"	"14.9"	"22.0"	"30.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35754"	"Glutaredoxin-1 OS=Homo sapiens OX=9606 GN=GLRX PE=1 SV=2"	"20"	"1"	"1"	"1"	"106"	"11.8"	"8.09"	""	"3.58"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf00462"	"2745"	"ENSG00000173221"	"GLRX"	"B2R4L2; hsa:2745; P35754; Q3KQS1; Q6ICT1"	"One-carbon metabolism"	"Interconversion of nucleotide di- and triphosphates"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5TDH0"	"Protein DDI1 homolog 2 OS=Homo sapiens OX=9606 GN=DDI2 PE=1 SV=1"	"4"	"1"	"2"	"1"	"399"	"44.5"	"5.05"	"263.90"	"3.58"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00240, Pf09668"	"84301"	"ENSG00000197312"	"DDI2"	"A8KAE1; hsa:84301; Q5TDH0; Q7RTZ0; Q9BRT1"	""	""	"0"	"0"	"24.8"	"76.3"	"78.6"	"20.4"	"60.1"	"26.1"	"44.9"	"41.1"	"52.3"	"69.6"	"112.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14617"	"AP-3 complex subunit delta-1 OS=Homo sapiens OX=9606 GN=AP3D1 PE=1 SV=1"	"2"	"2"	"3"	"2"	"1153"	"130.1"	"8.48"	"946.05"	"3.58"	"2"	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf01602, Pf06375"	"8943"	"ENSG00000065000"	"AP3D1"	"hsa:8943; O00202; O14617; O75262; Q59HF5; Q96G11; Q9H3C6"	""	""	"0"	"0"	"57.7"	"73.3"	"87.7"	"39.3"	"81.8"	"53.9"	"147.6"	"117.6"	"214.6"	"277.7"	"345.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14406"	"Cytochrome c oxidase subunit 7A2, mitochondrial OS=Homo sapiens OX=9606 GN=COX7A2 PE=1 SV=1"	"23"	"2"	"3"	"2"	"83"	"9.4"	"9.76"	"339.74"	"3.57"	"1"	"2"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf02238"	"1347"	"ENSG00000112695"	"COX7A2"	"B2R5E1; hsa:1347; P14406; Q3MIH5; Q5TF59; Q6FGI2"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex IV assembly"	""	"3"	"0"	"170.8"	"270.4"	"345.5"	"108.5"	"348.1"	"210.5"	"229.1"	"145.9"	"220.4"	"263.0"	"414.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15050"	"Ribosome biogenesis regulatory protein homolog OS=Homo sapiens OX=9606 GN=RRS1 PE=1 SV=2"	"3"	"1"	"2"	"1"	"365"	"41.2"	"10.70"	"379.50"	"3.57"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity"	"Pf04939"	"23212"	"ENSG00000179041"	"RRS1"	"hsa:23212; Q15050; Q9BUX8"	""	""	"0"	"0"	"34.1"	"80.4"	"103.8"	"46.3"	"88.9"	"42.2"	"124.9"	"62.7"	"123.0"	"109.0"	"157.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31151"	"Protein S100-A7 OS=Homo sapiens OX=9606 GN=S100A7 PE=1 SV=4"	"23"	"2"	"3"	"2"	"101"	"11.5"	"6.77"	"735.02"	"3.57"	"2"	"1"	"stress response;developmental processes;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01023"	"6278"	"ENSG00000143556"	"S100A7"	"hsa:6278; P31151; Q5SY67; Q6FGE3; Q9H1E2"	""	"Neutrophil degranulation; Metal sequestration by antimicrobial proteins"	"2"	"0"	"5.4"	"15.2"	"25.7"	"7.3"	"14.5"	"10.1"	"47.9"	"42.5"	"51.1"	"53.2"	"58.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00291"	"Huntingtin-interacting protein 1 OS=Homo sapiens OX=9606 GN=HIP1 PE=1 SV=5"	"1"	"1"	"2"	"1"	"1037"	"116.1"	"5.30"	"359.71"	"3.57"	"1"	"1"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf01608, Pf07651, Pf16515"	"3092"	"ENSG00000127946"	"HIP1"	"B4E3I7; E7ES17; hsa:3092; O00291; O00328; Q2TB58; Q8TDL4; V5LU97"	"DYRK1A involvement regarding cell proliferation in brain development"	"Clathrin-mediated endocytosis; ALK mutants bind TKIs; Signaling by ALK fusions and activated point mutants"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BT25"	"HAUS augmin-like complex subunit 8 OS=Homo sapiens OX=9606 GN=HAUS8 PE=1 SV=3"	"4"	"1"	"2"	"1"	"410"	"44.8"	"7.06"	"449.80"	"3.56"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	""	"93323"	"ENSG00000131351"	"HAUS8"	"B4DJA7; C9JBZ4; hsa:93323; Q49AC4; Q86WF0; Q96FX3; Q9BT25"	""	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"7"	"0"	"16.0"	"14.0"	"14.6"	"10.5"	"16.2"	"10.3"	"34.4"	"31.3"	"42.9"	"52.1"	"69.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N0X4"	"Citramalyl-CoA lyase, mitochondrial OS=Homo sapiens OX=9606 GN=CLYBL PE=1 SV=2"	"4"	"1"	"1"	"1"	"340"	"37.3"	"8.73"	""	"3.56"	""	"1"	"cell organization and biogenesis;other biological processes"	"mitochondrion"	"other molecular function"	"Pf03328"	"171425"	"ENSG00000125246"	"CLYBL"	"hsa:171425; Q5W0F7; Q8N0X4; Q8TDH8"	""	""	"0"	"0"	"17.7"	"65.1"	"70.8"	"28.8"	"62.5"	"29.2"	"50.3"	"44.7"	"88.7"	"160.6"	"316.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15042"	"U2 snRNP-associated SURP motif-containing protein OS=Homo sapiens OX=9606 GN=U2SURP PE=1 SV=2"	"3"	"2"	"3"	"2"	"1029"	"118.2"	"8.47"	"755.21"	"3.56"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf00076, Pf01805, Pf04818, Pf08312"	"23350"	"ENSG00000163714"	"U2SURP"	"A0PJ60; hsa:23350; O15042; Q0D2M1; Q2NKQ7; Q9BR70"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"72.9"	"82.4"	"103.8"	"49.6"	"108.7"	"68.1"	"143.0"	"91.1"	"163.0"	"180.5"	"202.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NPA0"	"ER membrane protein complex subunit 7 OS=Homo sapiens OX=9606 GN=EMC7 PE=1 SV=1"	"5"	"1"	"2"	"1"	"242"	"26.5"	"9.25"	"244.05"	"3.55"	"1"	"1"	"cell organization and biogenesis"	"other membranes;ER/Golgi"	"other molecular function"	"Pf09430"	"56851"	"ENSG00000134153"	"EMC7"	"B2RC00; hsa:56851; Q96ED5; Q9NPA0"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BZF9"	"Uveal autoantigen with coiled-coil domains and ankyrin repeats OS=Homo sapiens OX=9606 GN=UACA PE=1 SV=2"	"1"	"1"	"2"	"1"	"1416"	"162.4"	"7.03"	"351.98"	"3.55"	"1"	"1"	"other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus"	"cytoskeletal activity"	"Pf12796"	"55075"	"ENSG00000137831"	"UACA"	"G3XAG2; hsa:55075; Q14DD3; Q8N3B8; Q96NH6; Q9BZF9; Q9HCL1; Q9NWC6"	""	"Regulation of the apoptosome activity; RHOH GTPase cycle"	"2"	"0"	"5.1"	"13.2"	"12.8"	"2.9"	"11.7"	"6.1"	"16.4"	"34.9"	"81.3"	"151.0"	"242.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92738"	"USP6 N-terminal-like protein OS=Homo sapiens OX=9606 GN=USP6NL PE=1 SV=3"	"3"	"2"	"3"	"2"	"828"	"94.0"	"9.07"	"771.68"	"3.55"	"2"	"1"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00566"	"9712"	"ENSG00000148429"	"USP6NL"	"A8KA79; hsa:9712; Q15400; Q5VV10; Q7L0K9; Q92738"	"EGF/EGFR signaling pathway"	"Retrograde transport at the Trans-Golgi-Network"	"2"	"0"	"33.3"	"34.7"	"43.5"	"24.9"	"57.3"	"40.2"	"112.9"	"114.0"	"173.7"	"213.6"	"288.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BW71"	"HIRA-interacting protein 3 OS=Homo sapiens OX=9606 GN=HIRIP3 PE=1 SV=3"	"3"	"1"	"2"	"1"	"556"	"61.9"	"8.54"	"432.09"	"3.54"	"1"	"1"	"cell organization and biogenesis"	"nucleus"	""	"Pf09649"	"8479"	"ENSG00000149929"	"HIRIP3"	"H3BSR3; hsa:8479; O75707; O75708; Q9BW71"	"22q11.2 copy number variation syndrome; 16p11.2 proximal deletion syndrome"	""	"2"	"0"	"4.8"	"9.4"	"8.2"	"3.6"	"8.9"	"5.6"	"13.9"	"11.7"	"18.8"	"14.6"	"19.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99453"	"Paired mesoderm homeobox protein 2B OS=Homo sapiens OX=9606 GN=PHOX2B PE=1 SV=2"	"3"	"1"	"2"	"1"	"314"	"31.6"	"8.84"	"431.99"	"3.54"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00046"	"8929"	"ENSG00000109132"	"PHOX2B"	"hsa:8929; Q6PJD9; Q99453"	"Neural crest differentiation; Sudden infant death syndrome (SIDS) susceptibility pathways"	""	"2"	"0"	"4.2"	"17.8"	"14.3"	"5.1"	"17.6"	"6.2"	"39.6"	"31.4"	"42.7"	"41.4"	"67.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6IBS0"	"Twinfilin-2 OS=Homo sapiens OX=9606 GN=TWF2 PE=1 SV=2"	"4"	"1"	"2"	"1"	"349"	"39.5"	"6.84"	"305.25"	"3.53"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00241"	"11344"	"ENSG00000247596"	"TWF2"	"hsa:11344; Q6IBS0; Q9Y3F5"	""	"Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P5R6"	"60S ribosomal protein L22-like 1 OS=Homo sapiens OX=9606 GN=RPL22L1 PE=1 SV=2"	"10"	"1"	"2"	"1"	"122"	"14.6"	"9.38"	"241.68"	"3.52"	"1"	"1"	"protein metabolism;other metabolic processes"	"translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01776"	"200916"	"ENSG00000163584"	"RPL22L1"	"hsa:200916; Q32Q77; Q6P5R6"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"13"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IY67"	"Ribonucleoprotein PTB-binding 1 OS=Homo sapiens OX=9606 GN=RAVER1 PE=1 SV=1"	"2"	"1"	"2"	"1"	"606"	"63.8"	"8.48"	"465.60"	"3.52"	"1"	"1"	""	"nucleus;other cell component"	""	"Pf00076"	"125950"	""	"RAVER1"	"A6NMU4; hsa:125950; Q8IY60; Q8IY67; Q8TF24"	""	""	"0"	"0"	"18.9"	"39.9"	"34.3"	"11.0"	"34.4"	"23.4"	"24.1"	"22.3"	"32.7"	"35.7"	"55.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50579"	"Methionine aminopeptidase 2 OS=Homo sapiens OX=9606 GN=METAP2 PE=1 SV=1"	"7"	"2"	"2"	"2"	"478"	"52.9"	"5.82"	"283.58"	"3.52"	"1"	"1"	"protein metabolism;other metabolic processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00557"	"10988"	"ENSG00000111142"	"METAP2"	"B2RDI8; B4DUX5; G3XA91; hsa:10988; P50579; Q8NB11"	""	"Inactivation, recovery and regulation of the phototransduction cascade"	"1"	"0"	"21.6"	"40.2"	"43.9"	"22.5"	"44.9"	"23.7"	"56.5"	"56.4"	"84.7"	"86.6"	"122.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60925"	"Prefoldin subunit 1 OS=Homo sapiens OX=9606 GN=PFDN1 PE=1 SV=2"	"9"	"1"	"2"	"1"	"122"	"14.2"	"6.81"	"421.78"	"3.51"	"1"	"1"	"other biological processes"	"other cell component"	"other molecular function"	"Pf01920"	"5201"	"ENSG00000113068"	"PFDN1"	"B2RD02; hsa:5201; O60925; Q53F95; Q96EX6"	"Cellular proteostasis; 11p11.2 copy number variation syndrome"	"Prefoldin mediated transfer of substrate  to CCT/TriC"	"3"	"0"	"84.5"	"290.4"	"241.4"	"54.6"	"207.4"	"88.7"	"120.9"	"88.3"	"120.1"	"159.3"	"242.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NUQ3"	"Gamma-taxilin OS=Homo sapiens OX=9606 GN=TXLNG PE=1 SV=2"	"2"	"1"	"2"	"1"	"528"	"60.5"	"7.52"	"299.81"	"3.51"	"1"	"1"	"cell cycle OR cell proliferation;other biological processes"	"other membranes;cytosol;nucleus"	"other molecular function"	"Pf09728"	"55787"	"ENSG00000086712"	"TXLNG"	"hsa:55787; Q2KQ75; Q5JNZ7; Q9NUQ3; Q9P0X1"	""	""	"0"	"0"	"4.9"	"12.8"	"16.8"	"4.1"	"12.3"	"4.4"	"10.3"	"9.6"	"20.4"	"48.0"	"99.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UHD1"	"Cysteine and histidine-rich domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHORDC1 PE=1 SV=2"	"5"	"1"	"2"	"1"	"332"	"37.5"	"7.87"	"355.88"	"3.50"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	""	"other molecular function"	"Pf04968, Pf04969"	"26973"	"ENSG00000110172; ENSG00000285023"	"CHORDC1"	"B2R6P8; hsa:26973; Q6IN49; Q8WVL9; Q9H3D6; Q9UHD1"	""	""	"0"	"0"	"21.6"	"120.2"	"128.2"	"14.3"	"109.4"	"32.8"	"58.0"	"34.6"	"62.9"	"95.7"	"175.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z4H3"	"5'-deoxynucleotidase HDDC2 OS=Homo sapiens OX=9606 GN=HDDC2 PE=1 SV=1"	"8"	"1"	"2"	"1"	"204"	"23.4"	"5.49"	"445.62"	"3.50"	"1"	"1"	""	""	"other molecular function"	"Pf13023"	"51020"	"ENSG00000111906"	"HDDC2"	"hsa:51020; Q5TDQ4; Q6NZ49; Q7Z4H3; Q9BTT2; Q9BV31; Q9Y3D1"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5VUA4"	"Zinc finger protein 318 OS=Homo sapiens OX=9606 GN=ZNF318 PE=1 SV=2"	"1"	"2"	"3"	"2"	"2279"	"251.0"	"7.20"	"618.59"	"3.49"	"2"	"1"	"cell cycle OR cell proliferation;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	""	"24149"	"ENSG00000171467"	"ZNF318"	"hsa:24149; O94796; Q4G0E4; Q5VUA4; Q8NEM6; Q9UNU8; Q9Y2W9"	"Androgen receptor signaling pathway"	""	"1"	"0"	"8.2"	"14.7"	"21.8"	"8.7"	"15.9"	"13.3"	"23.1"	"20.2"	"27.4"	"40.2"	"50.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y530"	"ADP-ribose glycohydrolase OARD1 OS=Homo sapiens OX=9606 GN=OARD1 PE=1 SV=2"	"8"	"1"	"2"	"1"	"152"	"17.0"	"8.31"	"262.75"	"3.48"	"1"	"1"	"protein metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf01661"	"221443"	"ENSG00000124596"	"OARD1"	"A6NEK4; A8K4H4; hsa:221443; Q96F23; Q9Y530"	""	""	"0"	"0"	"28.4"	"48.6"	"46.2"	"28.1"	"51.7"	"27.4"	"54.9"	"46.7"	"64.3"	"79.3"	"119.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NB90"	"ATPase family protein 2 homolog OS=Homo sapiens OX=9606 GN=SPATA5 PE=1 SV=3"	"2"	"2"	"3"	"1"	"893"	"97.8"	"5.66"	"295.11"	"3.48"	"1"	"2"	"developmental processes;other biological processes"	"cytoskeleton;mitochondrion;other cell component"	"other molecular function"	"Pf00004, Pf17862"	"166378"	"ENSG00000145375"	"AFG2A"	"C9JT97; hsa:166378; Q86XW1; Q8NB90; Q8NI20; Q8TDL7"	""	""	"0"	"0"	"75.2"	"137.8"	"192.1"	"99.7"	"212.5"	"193.7"	"203.3"	"129.7"	"166.5"	"181.1"	"241.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12979"	"Active breakpoint cluster region-related protein OS=Homo sapiens OX=9606 GN=ABR PE=1 SV=2"	"2"	"1"	"2"	"1"	"859"	"97.5"	"6.55"	"294.11"	"3.47"	"1"	"1"	"signal transduction;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity"	"Pf00168, Pf00169, Pf00620, Pf00621"	"29"	"ENSG00000159842; ENSG00000276016; ENSG00000278741"	"ABR"	"B3KW89; B7Z6H7; D3DTH3; D3DTH4; F5H3S2; F5H8B3; hsa:29; Q12979; Q13693; Q13694"	""	"RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RAC3 GTPase cycle; NRAGE signals death through JNK; G alpha (12/13) signalling events; RHOC GTPase cycle; RAC2 GTPase cycle; RHOB GTPase cycle"	"9"	"0"	"18.7"	"49.4"	"46.5"	"22.0"	"49.0"	"26.3"	"45.5"	"52.8"	"101.8"	"141.9"	"210.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y371"	"Endophilin-B1 OS=Homo sapiens OX=9606 GN=SH3GLB1 PE=1 SV=1"	"6"	"1"	"1"	"1"	"365"	"40.8"	"6.04"	""	"3.47"	""	"1"	"cell organization and biogenesis;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf03114, Pf14604"	"51100"	"ENSG00000097033"	"SH3GLB1"	"B4E182; hsa:51100; Q5H8U5; Q9H3Z0; Q9NR47; Q9NYA9; Q9Y371"	"Nanoparticle triggered autophagic cell death"	""	"1"	"0"	"0.0"	"20.7"	"16.3"	"1.2"	"9.6"	"0.0"	"8.6"	"5.2"	"8.1"	"15.4"	"26.8"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61081"	"NEDD8-conjugating enzyme Ubc12 OS=Homo sapiens OX=9606 GN=UBE2M PE=1 SV=1"	"6"	"1"	"2"	"1"	"183"	"20.9"	"7.69"	"291.39"	"3.47"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00179"	"9040"	"ENSG00000130725"	"UBE2M"	"hsa:9040; O76069; P61081; Q8VC50"	""	"Antigen processing: Ubiquitination & Proteasome degradation; Dectin-1 mediated noncanonical NF-kB signaling; NIK-->noncanonical NF-kB signaling; Neddylation; TGF-beta receptor signaling activates SMADs"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00193"	"Small acidic protein OS=Homo sapiens OX=9606 GN=SMAP PE=1 SV=1"	"4"	"1"	"2"	"1"	"183"	"20.3"	"4.72"	"347.77"	"3.46"	"1"	"1"	""	""	""	"Pf15477"	"10944"	"ENSG00000110696"	"SMAP"	"B2RD28; hsa:10944; O00193"	""	""	"0"	"0"	"176.7"	"540.3"	"480.7"	"107.1"	"456.2"	"461.0"	"494.1"	"298.0"	"363.4"	"458.4"	"721.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9GZT9"	"Egl nine homolog 1 OS=Homo sapiens OX=9606 GN=EGLN1 PE=1 SV=1"	"3"	"1"	"2"	"1"	"426"	"46.0"	"8.53"	"303.37"	"3.46"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01753, Pf13640"	"54583"	"ENSG00000135766"	"EGLN1"	"hsa:54583; Q8N3M8; Q9BZS8; Q9BZT0; Q9GZT9"	"Photodynamic therapy-induced HIF-1 survival signaling; Type 2 papillary renal cell carcinoma; Markers of kidney cell lineage"	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"	"4"	"0"	"16.8"	"56.6"	"50.1"	"10.8"	"48.3"	"21.1"	"60.4"	"36.9"	"48.4"	"59.1"	"84.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05204"	"Non-histone chromosomal protein HMG-17 OS=Homo sapiens OX=9606 GN=HMGN2 PE=1 SV=3"	"24"	"2"	"3"	"2"	"90"	"9.4"	"9.99"	"576.99"	"3.46"	"2"	"1"	"cell organization and biogenesis;stress response;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01101"	"3151"	"ENSG00000198830"	"HMGN2"	"hsa:3151; P05204; Q0VGD5; Q6FGI5; Q96C64"	""	""	"0"	"0"	"150.1"	"198.9"	"238.6"	"89.7"	"289.3"	"138.9"	"487.1"	"264.4"	"450.8"	"773.4"	"873.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14135"	"Transcription cofactor vestigial-like protein 4 OS=Homo sapiens OX=9606 GN=VGLL4 PE=1 SV=4"	"6"	"1"	"2"	"1"	"290"	"30.9"	"8.22"	"352.24"	"3.45"	"1"	"1"	"other biological processes"	"nucleus"	"other molecular function"	"Pf15245"	"9686"	"ENSG00000144560"	"VGLL4"	"B4DTS7; hsa:9686; J3KN68; Q14135; Q7L5V0; Q9BQ78"	"Hippo-Merlin signaling dysregulation; Pleural mesothelioma"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13640"	"Metallothionein-1G OS=Homo sapiens OX=9606 GN=MT1G PE=1 SV=2"	"19"	"1"	"1"	"1"	"62"	"6.1"	"7.96"	""	"3.45"	""	"1"	"other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00131"	"4495"	"ENSG00000125144"	"MT1G"	"hsa:4495; P13640; P80296"	"Copper homeostasis; Zinc homeostasis"	"Metallothioneins bind metals"	"3"	"0"	"31.2"	"81.1"	"86.2"	"31.1"	"94.5"	"36.2"	"57.3"	"40.0"	"67.7"	"70.3"	"120.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NFW8"	"N-acylneuraminate cytidylyltransferase OS=Homo sapiens OX=9606 GN=CMAS PE=1 SV=2"	"3"	"1"	"2"	"1"	"434"	"48.3"	"7.93"	"370.01"	"3.44"	"1"	"1"	"other metabolic processes"	"nucleus"	"other molecular function"	"Pf02348"	"55907"	"ENSG00000111726"	"CMAS"	"hsa:55907; Q8NFW8; Q96AX5; Q9NQZ0"	""	"Sialic acid metabolism"	"1"	"0"	"9.8"	"5.6"	"30.7"	"7.5"	"25.1"	"25.1"	"51.3"	"24.2"	"23.4"	"47.9"	"44.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4B6"	"DDB1- and CUL4-associated factor 1 OS=Homo sapiens OX=9606 GN=DCAF1 PE=1 SV=3"	"1"	"1"	"2"	"1"	"1507"	"168.9"	"5.06"	"308.40"	"3.44"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	""	"9730"	"ENSG00000145041"	"DCAF1"	"hsa:9730; Q2YD74; Q8TBD9; Q9HCA1; Q9UG37; Q9Y4B6"	"Hippo-Merlin signaling dysregulation"	"Antigen processing: Ubiquitination & Proteasome degradation"	"2"	"0"	"12.0"	"22.1"	"20.0"	"8.3"	"28.2"	"17.1"	"20.2"	"18.0"	"23.9"	"36.3"	"32.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UNS2"	"COP9 signalosome complex subunit 3 OS=Homo sapiens OX=9606 GN=COPS3 PE=1 SV=3"	"4"	"1"	"4"	"1"	"423"	"47.8"	"6.65"	"946.65"	"3.43"	"1"	"1"	"protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf01399"	"8533"	"ENSG00000141030"	"COPS3"	"B2R683; B4DY81; hsa:8533; O43191; Q7LDR6; Q9UNS2"	"Ciliary landscape"	"Neddylation; Cargo recognition for clathrin-mediated endocytosis; Formation of TC-NER Pre-Incision Complex; DNA Damage Recognition in GG-NER"	"5"	"0"	"25.6"	"52.1"	"53.9"	"20.8"	"51.7"	"21.0"	"36.8"	"19.5"	"41.0"	"50.8"	"73.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61289"	"Proteasome activator complex subunit 3 OS=Homo sapiens OX=9606 GN=PSME3 PE=1 SV=1"	"6"	"1"	"2"	"1"	"254"	"29.5"	"5.95"	"418.11"	"3.43"	"1"	"1"	"cell cycle OR cell proliferation;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02251, Pf02252"	"10197"	"ENSG00000131467"	"PSME3"	"A8K9A3; hsa:10197; O35563; P61289; P97373; Q12920; Q13172; Q9BQD9"	"Proteasome degradation"	"Regulation of expression of SLITs and ROBOs; ER-Phagosome pathway; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"60"	"0"	"20.1"	"90.5"	"80.6"	"21.0"	"46.3"	"24.7"	"41.3"	"27.0"	"42.2"	"63.3"	"158.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P10644"	"cAMP-dependent protein kinase type I-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR1A PE=1 SV=1"	"5"	"1"	"1"	"1"	"381"	"43.0"	"5.35"	""	"3.42"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00027, Pf02197"	"5573"	"ENSG00000108946"	"PRKAR1A"	"hsa:5573; K7ER48; P10644; Q567S7"	"Mesodermal commitment pathway; Myometrial relaxation and contraction pathways; Mesodermal commitment pathway; G protein signaling pathways; Cannabinoid receptor signaling; Lipid metabolism pathway; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; Fragile X syndrome; Cardiomyocyte signaling pathways converging on Titin; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Hedgehog 'off' state; FCGR3A-mediated IL10 synthesis; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production; ALK mutants bind TKIs; Signaling by ALK fusions and activated point mutants; Factors involved in megakaryocyte development and platelet production; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Vasopressin regulates renal water homeostasis via Aquaporins; PKA activation; PKA activation in glucagon signalling; DARPP-32 events; CREB1 phosphorylation through the activation of Adenylate Cyclase"	"25"	"0"	"10.3"	"31.4"	"31.1"	"9.3"	"28.6"	"14.5"	"18.6"	"16.0"	"25.6"	"30.8"	"32.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13554"	"Calcium/calmodulin-dependent protein kinase type II subunit beta OS=Homo sapiens OX=9606 GN=CAMK2B PE=1 SV=3"	"3"	"1"	"2"	"1"	"666"	"72.6"	"7.27"	"380.42"	"3.42"	"1"	"1"	"protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;kinase activity;other molecular function"	"Pf00069, Pf08332"	"816"	"ENSG00000058404"	"CAMK2B"	"A4D2K0; A4D2K1; A4D2K2; A4D2K3; A4D2K4; A4D2K5; A4D2K6; hsa:816; O95437; O95438; O95599; Q13554; Q9UGH7; Q9UGH8; Q9UGH9; Q9UNX0; Q9UNX7; Q9UP00; Q9Y5N4; Q9Y6F4"	"Primary focal segmental glomerulosclerosis (FSGS); Myometrial relaxation and contraction pathways; Serotonin and anxiety; NO/cGMP/PKG mediated neuroprotection; Wnt signaling; Non-genomic actions of 1,25 dihydroxyvitamin D3; Synaptic signaling pathways associated with autism spectrum disorder; Fragile X syndrome; Disruption of postsynaptic signaling by CNV; Neuroinflammation and glutamatergic signaling; GDNF signaling; Hippocampal synaptogenesis and neurogenesis; Calcium regulation in cardiac cells; ErbB signaling pathway"	"Signaling by BRAF and RAF1 fusions; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; Assembly and cell surface presentation of NMDA receptors; Ion homeostasis; Ion transport by P-type ATPases; Interferon gamma signaling; RAF activation; Ras activation upon Ca2+ influx through NMDA receptor; Regulation of MECP2 expression and activity; Unblocking of NMDA receptors, glutamate binding and activation; Negative regulation of NMDA receptor-mediated neuronal transmission; Long-term potentiation; Trafficking of AMPA receptors; Phase 0 - rapid depolarisation; HSF1-dependent transactivation; CaMK IV-mediated phosphorylation of CREB; CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde"	"35"	"0"	"3.3"	"14.6"	"15.4"	"6.6"	"14.6"	"6.3"	"11.9"	"9.8"	"9.9"	"18.0"	"26.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q08257"	"Quinone oxidoreductase OS=Homo sapiens OX=9606 GN=CRYZ PE=1 SV=1"	"6"	"2"	"3"	"2"	"329"	"35.2"	"8.44"	"642.70"	"3.42"	"2"	"1"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"cytosol"	"nucleic acid binding activity;other molecular function"	"Pf08240, Pf13602"	"1429"	"ENSG00000116791"	"CRYZ"	"A6NN60; D3DQ76; hsa:1429; Q08257; Q53FT0; Q59EU7; Q5HYE7; Q6NSK9"	""	""	"0"	"0"	"66.6"	"163.1"	"157.9"	"54.5"	"141.7"	"68.8"	"152.1"	"109.3"	"145.5"	"179.8"	"274.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5HYI8"	"Rab-like protein 3 OS=Homo sapiens OX=9606 GN=RABL3 PE=1 SV=1"	"5"	"1"	"2"	"1"	"236"	"26.4"	"7.11"	"304.85"	"3.42"	"1"	"1"	"transport;other biological processes"	"other cell component"	"other molecular function"	"Pf08477"	"285282"	"ENSG00000144840"	"RABL3"	"hsa:285282; Q5HYI8; Q8WUD3"	""	""	"0"	"0"	"10.0"	"37.2"	"32.9"	"13.5"	"29.7"	"13.0"	"38.6"	"29.1"	"42.6"	"56.9"	"93.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q00403"	"Transcription initiation factor IIB OS=Homo sapiens OX=9606 GN=GTF2B PE=1 SV=1"	"5"	"1"	"2"	"1"	"316"	"34.8"	"8.35"	"409.39"	"3.41"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00382, Pf08271"	"2959"	"ENSG00000137947"	"GTF2B"	"A8K1A7; hsa:2959; Q00403; Q5JS30"	"Eukaryotic transcription initiation"	"RNA Polymerase II Pre-transcription Events; RNA polymerase II transcribes snRNA genes; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation"	"10"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P53618"	"Coatomer subunit beta OS=Homo sapiens OX=9606 GN=COPB1 PE=1 SV=3"	"2"	"1"	"2"	"1"	"953"	"107.1"	"6.05"	"374.87"	"3.41"	"1"	"1"	"transport"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf01602, Pf07718, Pf14806"	"1315"	"ENSG00000129083"	"COPB1"	"D3DQX0; hsa:1315; P53618; Q6GTT7; Q9NTK2; Q9UNW7"	""	"Neutrophil degranulation; COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport"	"3"	"0"	"27.0"	"70.9"	"72.4"	"31.7"	"78.2"	"30.7"	"52.6"	"37.5"	"58.4"	"77.5"	"105.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NQP4"	"Prefoldin subunit 4 OS=Homo sapiens OX=9606 GN=PFDN4 PE=1 SV=1"	"11"	"1"	"2"	"1"	"134"	"15.3"	"4.53"	"387.23"	"3.41"	"1"	"1"	"other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01920"	"5203"	"ENSG00000101132"	"PFDN4"	"hsa:5203; Q5TD11; Q92779; Q9NQP4"	"Cellular proteostasis"	"Prefoldin mediated transfer of substrate  to CCT/TriC"	"2"	"0"	"64.2"	"126.8"	"132.3"	"55.2"	"119.5"	"64.0"	"98.7"	"72.5"	"101.4"	"100.1"	"158.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P56385"	"ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2"	"17"	"2"	"3"	"2"	"69"	"7.9"	"9.35"	"738.45"	"3.39"	"2"	"1"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf05680"	"521"	"ENSG00000169020"	"ATP5ME"	"hsa:521; P56385; Q0D2L9"	"Electron transport chain: OXPHOS system in mitochondria; Oxidative phosphorylation"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"4"	"0"	"54.4"	"88.9"	"93.5"	"44.1"	"113.2"	"65.9"	"146.3"	"123.6"	"151.1"	"218.8"	"271.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96E11"	"Ribosome-recycling factor, mitochondrial OS=Homo sapiens OX=9606 GN=MRRF PE=1 SV=1"	"4"	"1"	"2"	"1"	"262"	"29.3"	"9.79"	"335.71"	"3.38"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"mitochondrion"	"translation activity"	"Pf01765"	"92399"	"ENSG00000148187"	"MRRF"	"A8K6D8; A8K6Z4; B7Z4X5; B7Z6P7; hsa:92399; Q5RKT1; Q5T7T0; Q5T7T1; Q5T7T2; Q5T7T3; Q5T7T4; Q5T7T5; Q96E11"	""	"Mitochondrial translation termination"	"1"	"0"	"40.1"	"98.2"	"93.3"	"30.6"	"83.8"	"39.4"	"210.4"	"163.8"	"265.5"	"613.9"	"1616.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQ69"	"ADP-ribose glycohydrolase MACROD1 OS=Homo sapiens OX=9606 GN=MACROD1 PE=1 SV=2"	"3"	"1"	"2"	"1"	"325"	"35.5"	"9.51"	"442.12"	"3.37"	"1"	"1"	"protein metabolism;other metabolic processes;stress response"	"nucleus"	"other molecular function"	"Pf01661"	"28992"	"ENSG00000133315"	"MACROD1"	"hsa:28992; Q9BQ69; Q9UH96"	""	""	"0"	"0"	"24.5"	"47.2"	"38.4"	"23.7"	"38.2"	"24.8"	"92.1"	"74.1"	"104.1"	"176.4"	"312.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKL0"	"REST corepressor 1 OS=Homo sapiens OX=9606 GN=RCOR1 PE=1 SV=2"	"3"	"1"	"2"	"1"	"485"	"53.3"	"7.03"	"382.39"	"3.37"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00249, Pf01448"	"23186"	"ENSG00000089902"	"RCOR1"	"hsa:23186; J3KN32; Q15044; Q6P2I9; Q86VG5; Q9UKL0"	""	"Factors involved in megakaryocyte development and platelet production; Potential therapeutics for SARS; Regulation of PTEN gene transcription; HDACs deacetylate histones"	"4"	"0"	"18.7"	"34.6"	"36.6"	"14.2"	"35.0"	"18.3"	"40.9"	"24.4"	"42.1"	"74.2"	"104.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35613"	"Basigin OS=Homo sapiens OX=9606 GN=BSG PE=1 SV=2"	"8"	"3"	"4"	"3"	"385"	"42.2"	"5.66"	"866.66"	"3.36"	"3"	"1"	"developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf13927"	"682"	"ENSG00000172270"	"BSG"	"A6NJW1; D3YLG5; hsa:682; P35613; Q7Z796; Q8IZL7"	"Matrix metalloproteinases; VEGFA-VEGFR2 signaling; IL-18 signaling pathway"	"Degradation of the extracellular matrix; Integrin cell surface interactions; Pyruvate metabolism; Aspirin ADME; Basigin interactions; Proton-coupled monocarboxylate transport; Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT)"	"10"	"0"	"178.0"	"598.8"	"518.0"	"132.0"	"435.5"	"200.6"	"267.0"	"191.1"	"298.3"	"388.8"	"643.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q4G0A6"	"Probable ubiquitin carboxyl-terminal hydrolase MINDY-4 OS=Homo sapiens OX=9606 GN=MINDY4 PE=1 SV=2"	"1"	"1"	"2"	"1"	"757"	"84.3"	"6.90"	"351.70"	"3.36"	"1"	"1"	"protein metabolism;other metabolic processes"	""	"other molecular function"	"Pf13898"	"84182"	"ENSG00000106125"	"MINDY4"	"hsa:84182; Q4G0A6; Q71AZ7; Q9H6D2"	""	""	"0"	"0"	"0.0"	"5.9"	"4.6"	"2.5"	"7.5"	"5.3"	"9.0"	"22.9"	"34.7"	"58.1"	"78.7"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NR45"	"Sialic acid synthase OS=Homo sapiens OX=9606 GN=NANS PE=1 SV=2"	"4"	"1"	"2"	"1"	"359"	"40.3"	"6.74"	"326.73"	"3.35"	"1"	"1"	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf03102"	"54187"	"ENSG00000095380"	"NANS"	"B2RE98; hsa:54187; Q8WUV9; Q9BWS6; Q9NR45; Q9NVD4"	""	"Sialic acid metabolism"	"1"	"0"	"18.1"	"94.0"	"91.2"	"19.2"	"60.8"	"28.8"	"54.5"	"43.0"	"56.3"	"50.6"	"117.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15075"	"Early endosome antigen 1 OS=Homo sapiens OX=9606 GN=EEA1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1411"	"162.4"	"5.68"	"295.12"	"3.35"	"1"	"1"	"cell-cell signaling;cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01363"	"8411"	"ENSG00000102189"	"EEA1"	"hsa:8411; Q14221; Q15075"	"VEGFA-VEGFR2 signaling"	"Toll Like Receptor 9 (TLR9) Cascade"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60510"	"Serine/threonine-protein phosphatase 4 catalytic subunit OS=Homo sapiens OX=9606 GN=PPP4C PE=1 SV=1"	"4"	"1"	"2"	"1"	"307"	"35.1"	"5.06"	"273.43"	"3.35"	"1"	"1"	"DNA metabolism;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00149"	"5531"	"ENSG00000149923"	"PPP4C"	"hsa:5531; P33172; P60510"	"16p11.2 proximal deletion syndrome"	"Processing of DNA double-strand break ends"	"2"	"0"	"16.0"	"38.3"	"42.6"	"15.8"	"32.6"	"22.4"	"36.8"	"23.5"	"41.6"	"53.6"	"79.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NP61"	"ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1"	"2"	"1"	"2"	"1"	"516"	"56.9"	"7.36"	"488.29"	"3.34"	"1"	"1"	"cell organization and biogenesis;transport"	"other membranes;cytosol;ER/Golgi"	"enzyme regulator activity;other molecular function"	"Pf01412"	"26286"	"ENSG00000242247"	"ARFGAP3"	"E9PB03; hsa:26286; Q9BSC6; Q9H9J0; Q9NP61; Q9NT10; Q9NUP5; Q9Y4V3; Q9Y4V4"	"Ciliary landscape"	"CDC42 GTPase cycle; COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport; RHOG GTPase cycle"	"5"	"0"	"26.7"	"64.1"	"57.2"	"31.3"	"59.9"	"35.7"	"58.3"	"49.9"	"65.8"	"84.0"	"116.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15907"	"Ras-related protein Rab-11B OS=Homo sapiens OX=9606 GN=RAB11B PE=1 SV=4"	"8"	"2"	"3"	"2"	"218"	"24.5"	"5.94"	"669.34"	"3.34"	"2"	"1"	"cell-cell signaling;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00071"	"9230"	"ENSG00000185236"	"RAB11B"	"A5YM50; B2R7I4; B4DMK0; D6W671; hsa:9230; Q15907; Q2YDT2; Q5U0I1; Q6FHR0; Q6FI42; Q8NI07"	"Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Intracellular trafficking proteins involved in CMT neuropathy"	"RAB geranylgeranylation; TBC/RABGAPs"	"4"	"0"	"115.5"	"347.0"	"280.2"	"79.3"	"258.0"	"107.7"	"105.4"	"96.1"	"139.6"	"168.2"	"290.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51665"	"26S proteasome non-ATPase regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMD7 PE=1 SV=2"	"3"	"1"	"2"	"1"	"324"	"37.0"	"6.77"	"281.60"	"3.34"	"1"	"1"	"protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf01398, Pf13012"	"5713"	"ENSG00000103035"	"PSMD7"	"D3DWS9; hsa:5713; P51665; Q6PKI2; Q96E97"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Ciliary landscape; Alzheimer's disease"	"Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Neutrophil degranulation; ER-Phagosome pathway; Regulation of expression of SLITs and ROBOs; Orc1 removal from chromatin; Assembly of the pre-replicative complex; Degradation of GLI1 by the proteasome; Hedgehog 'on' state; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"65"	"0"	"10.4"	"30.2"	"22.1"	"5.2"	"21.3"	"11.1"	"10.0"	"9.8"	"11.2"	"20.3"	"32.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14126"	"Desmoglein-2 OS=Homo sapiens OX=9606 GN=DSG2 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1118"	"122.2"	"5.24"	"371.93"	"3.33"	"1"	"1"	"cell adhesion;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00028"	"1829"	"ENSG00000046604"	"DSG2"	"hsa:1829; Q14126; Q4KKU6"	"Arrhythmogenic right ventricular cardiomyopathy; GDNF signaling"	"Formation of the cornified envelope; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; Apoptotic cleavage of cell adhesion  proteins"	"8"	"0"	"16.9"	"26.1"	"22.5"	"6.3"	"18.9"	"17.2"	"19.2"	"18.0"	"25.9"	"31.9"	"33.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P63151"	"Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R2A PE=1 SV=1"	"2"	"1"	"2"	"1"	"447"	"51.7"	"6.20"	"334.04"	"3.33"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity"	""	"5520"	"ENSG00000221914"	"PPP2R2A"	"B2RBU8; B4E1T7; hsa:5520; P50409; P63151; Q00007"	"Wnt signaling pathway and pluripotency; PI3K-Akt signaling pathway; Glycogen synthesis and degradation"	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Cyclin D associated events in G1; Cyclin A/B1/B2 associated events during G2/M transition; Initiation of Nuclear Envelope (NE) Reformation"	"7"	"0"	"13.5"	"45.7"	"35.8"	"9.2"	"30.8"	"7.4"	"20.8"	"19.9"	"29.8"	"43.5"	"86.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00471"	"Exocyst complex component 5 OS=Homo sapiens OX=9606 GN=EXOC5 PE=1 SV=1"	"2"	"1"	"2"	"1"	"708"	"81.8"	"6.71"	"394.24"	"3.33"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf07393"	"10640"	"ENSG00000070367"	"EXOC5"	"B2R6C5; hsa:10640; O00471; Q8IW24"	"Ciliary landscape"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EL3"	"39S ribosomal protein L53, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL53 PE=1 SV=1"	"13"	"1"	"2"	"1"	"112"	"12.1"	"8.76"	"454.86"	"3.32"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	""	"Pf10780"	"116540"	"ENSG00000204822"	"MRPL53"	"hsa:116540; Q96EL3"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"56.6"	"102.4"	"103.0"	"49.0"	"104.4"	"57.2"	"66.2"	"33.9"	"63.5"	"97.5"	"127.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49790"	"Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1475"	"153.8"	"8.73"	"398.07"	"3.32"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00641, Pf08604, Pf10599"	"9972"	"ENSG00000124789"	"NUP153"	"B4DIK2; E7EPX5; F6QR24; hsa:9972; P49790; Q4LE47; Q5T9I7; Q7Z743"	""	"Nuclear import of Rev protein; HCMV Late Events; HCMV Early Events; Transcriptional regulation by small RNAs; SUMOylation of DNA replication proteins; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"28"	"0"	"20.4"	"29.7"	"29.0"	"14.6"	"25.4"	"13.2"	"132.2"	"88.3"	"114.4"	"122.5"	"176.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12846"	"Syntaxin-4 OS=Homo sapiens OX=9606 GN=STX4 PE=1 SV=2"	"4"	"1"	"2"	"1"	"297"	"34.2"	"6.28"	"332.59"	"3.32"	"1"	"1"	"cell organization and biogenesis;stress response;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00804, Pf05739"	"6810"	"ENSG00000103496"	"STX4"	"A8MXY0; hsa:6810; Q12846; Q15525; Q6FHE8"	"Insulin signaling"	"ER-Phagosome pathway; Translocation of SLC2A4 (GLUT4) to the plasma membrane; trans-Golgi Network Vesicle Budding; Disinhibition of SNARE formation; Other interleukin signaling"	"6"	"0"	"6.8"	"22.6"	"17.6"	"5.5"	"19.6"	"4.8"	"12.2"	"9.2"	"9.4"	"14.4"	"29.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12849"	"G-rich sequence factor 1 OS=Homo sapiens OX=9606 GN=GRSF1 PE=1 SV=3"	"4"	"2"	"3"	"2"	"480"	"53.1"	"6.19"	"618.47"	"3.31"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"2926"	"ENSG00000132463"	"GRSF1"	"B3KPW0; hsa:2926; Q12849; Q4W5S5; Q6ZST3; Q8IWD6; Q8NBD2"	"VEGFA-VEGFR2 signaling"	"Viral mRNA Translation"	"2"	"0"	"82.2"	"294.8"	"302.1"	"78.2"	"231.7"	"104.0"	"143.4"	"105.9"	"189.6"	"227.5"	"363.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96J01"	"THO complex subunit 3 OS=Homo sapiens OX=9606 GN=THOC3 PE=1 SV=1"	"3"	"1"	"2"	"1"	"351"	"38.7"	"6.09"	"427.26"	"3.31"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00400, Pf08662, Pf12894"	"84321"	"ENSG00000051596"	"THOC3"	"hsa:84321; Q6NZ53; Q96J01"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"3"	"0"	"46.0"	"92.3"	"117.5"	"32.3"	"113.8"	"59.0"	"72.3"	"56.4"	"89.0"	"114.9"	"185.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43865"	"S-adenosylhomocysteine hydrolase-like protein 1 OS=Homo sapiens OX=9606 GN=AHCYL1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"530"	"58.9"	"6.89"	"314.86"	"3.31"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00670, Pf05221"	"10768"	"ENSG00000168710"	"AHCYL1"	"B4E168; hsa:10768; O43865; Q2TAJ6; Q502W8; Q5VSM0; Q6P171; Q96PK4; Q9UG84"	"Trans-sulfuration, one-carbon metabolism and related pathways"	"Role of phospholipids in phagocytosis; FCERI mediated Ca+2 mobilization; FCGR3A-mediated IL10 synthesis; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Ion homeostasis; Regulation of insulin secretion; VEGFR2 mediated cell proliferation; PLC beta mediated events; DAG and IP3 signaling; CLEC7A (Dectin-1) induces NFAT activation"	"11"	"0"	"6.4"	"25.8"	"26.9"	"13.3"	"29.4"	"16.3"	"45.5"	"24.5"	"35.5"	"40.8"	"77.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UK45"	"U6 snRNA-associated Sm-like protein LSm7 OS=Homo sapiens OX=9606 GN=LSM7 PE=1 SV=1"	"33"	"2"	"2"	"2"	"103"	"11.6"	"5.27"	"269.15"	"3.30"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01423"	"51690"	"ENSG00000130332"	"LSM7"	"hsa:51690; Q9UK45"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA decay by 5' to 3' exoribonuclease"	"3"	"0"	"67.9"	"277.7"	"250.2"	"40.4"	"209.0"	"64.6"	"126.7"	"90.2"	"135.5"	"181.7"	"358.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43395"	"U4/U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2"	"2"	"1"	"2"	"1"	"683"	"77.5"	"9.50"	"337.56"	"3.30"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf01480, Pf06544, Pf08572"	"9129"	"ENSG00000117360"	"PRPF3"	"B4DSY9; hsa:9129; O43395; O43446; Q5VT54"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"7.4"	"24.4"	"15.0"	"10.7"	"18.3"	"10.1"	"7.1"	"11.0"	"26.9"	"36.0"	"53.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EY7"	"Pentatricopeptide repeat domain-containing protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=PTCD3 PE=1 SV=3"	"5"	"2"	"3"	"2"	"689"	"78.5"	"6.42"	"646.13"	"3.30"	"2"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;translational apparatus;nucleus"	"translation activity;nucleic acid binding activity"	"Pf13041, Pf13812"	"55037"	"ENSG00000132300"	"PTCD3"	"A6NHD2; D6W5M1; hsa:55037; Q597H0; Q658Y9; Q96EY7; Q9BUZ8; Q9NWL0"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"9.1"	"19.7"	"20.5"	"6.3"	"22.8"	"10.5"	"19.4"	"9.4"	"19.4"	"34.3"	"53.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14203"	"Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3"	"1"	"1"	"2"	"1"	"1278"	"141.6"	"5.81"	"314.38"	"3.30"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01302, Pf12455"	"1639"	"ENSG00000204843"	"DCTN1"	"A8MY36; B4DM45; E9PFS5; E9PGE1; G5E9H4; hsa:1639; O95296; Q14203; Q6IQ37; Q9BRM9; Q9UIU1; Q9UIU2"	""	"MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Signaling by ALK fusions and activated point mutants; XBP1(S) activates chaperone genes"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5Z4"	"Heme-binding protein 2 OS=Homo sapiens OX=9606 GN=HEBP2 PE=1 SV=1"	"6"	"1"	"2"	"1"	"205"	"22.9"	"4.63"	"290.46"	"3.29"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"non-structural extracellular;mitochondrion;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf04832"	"23593"	"ENSG00000051620"	"HEBP2"	"hsa:23593; Q96P57; Q9Y5Z4"	""	"Neutrophil degranulation"	"1"	"0"	"9.3"	"116.5"	"73.4"	"2.4"	"60.6"	"13.3"	"18.3"	"12.8"	"17.6"	"18.6"	"65.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15057"	"Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ACAP2 PE=1 SV=3"	"1"	"1"	"2"	"1"	"778"	"88.0"	"6.80"	"334.86"	"3.29"	"1"	"1"	"transport;other biological processes"	"other membranes;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf01412, Pf12796, Pf16746"	"23527"	"ENSG00000114331"	"ACAP2"	"A8K2V4; hsa:23527; Q15057; Q8N5Z8; Q9UQR3"	""	""	"0"	"0"	"23.2"	"54.0"	"59.6"	"22.1"	"61.5"	"29.0"	"63.7"	"58.8"	"116.9"	"235.7"	"381.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NRN9"	"rRNA N6-adenosine-methyltransferase METTL5 OS=Homo sapiens OX=9606 GN=METTL5 PE=1 SV=1"	"7"	"1"	"2"	"1"	"209"	"23.7"	"6.68"	"335.98"	"3.27"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05175"	"29081"	"ENSG00000138382"	"METTL5"	"D3DPC9; hsa:29081; Q9NRN9; Q9NVX1"	""	""	"0"	"0"	"9.1"	"22.0"	"19.9"	"7.3"	"18.2"	"11.6"	"20.7"	"12.6"	"15.8"	"25.4"	"48.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P16219"	"Short-chain specific acyl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ACADS PE=1 SV=1"	"3"	"1"	"2"	"1"	"412"	"44.3"	"7.99"	"312.60"	"3.27"	"1"	"1"	"other metabolic processes"	"cytoskeleton;mitochondrion;nucleus"	"other molecular function"	"Pf00441, Pf02770, Pf02771"	"35"	"ENSG00000122971"	"ACADS"	"hsa:35; P16219; P78331"	"Fatty acid beta-oxidation; Mitochondrial long chain fatty acid beta-oxidation; IL-18 signaling pathway; Mitochondrial fatty acid oxidation disorders"	"Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of butanoyl-CoA to acetyl-CoA"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z4G4"	"tRNA (guanine(10)-N2)-methyltransferase homolog OS=Homo sapiens OX=9606 GN=TRMT11 PE=1 SV=1"	"3"	"1"	"2"	"1"	"463"	"53.4"	"7.78"	"468.19"	"3.26"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01170"	"60487"	"ENSG00000066651"	"TRMT11"	"E1P570; hsa:60487; Q5JY11; Q6PGQ5; Q7Z4G4; Q9HC13"	""	"tRNA modification in the nucleus and cytosol"	"1"	"0"	"8.5"	"20.8"	"21.0"	"6.9"	"19.7"	"8.7"	"15.3"	"10.4"	"15.6"	"15.6"	"23.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z4Q2"	"HEAT repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=HEATR3 PE=1 SV=2"	"2"	"1"	"2"	"1"	"680"	"74.5"	"5.11"	"308.20"	"3.25"	"1"	"1"	"transport;other biological processes"	""	"other molecular function"	"Pf13513"	"55027"	"ENSG00000155393"	"HEATR3"	"A8K1N4; hsa:55027; Q7Z4Q2; Q8N525; Q8WV56; Q96CC9; Q9NWN7"	""	""	"0"	"0"	"7.4"	"15.0"	"14.1"	"6.4"	"15.5"	"8.5"	"17.2"	"8.2"	"14.8"	"20.1"	"25.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P40616"	"ADP-ribosylation factor-like protein 1 OS=Homo sapiens OX=9606 GN=ARL1 PE=1 SV=1"	"9"	"1"	"3"	"1"	"181"	"20.4"	"5.72"	"750.81"	"3.24"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00025"	"400"	"ENSG00000120805"	"ARL1"	"B4DWW1; hsa:400; P40616; P80417; Q53XB1"	""	"Retrograde transport at the Trans-Golgi-Network"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16186"	"Proteasomal ubiquitin receptor ADRM1 OS=Homo sapiens OX=9606 GN=ADRM1 PE=1 SV=2"	"3"	"1"	"2"	"1"	"407"	"42.1"	"5.07"	"513.32"	"3.24"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf04683, Pf16550"	"11047"	"ENSG00000130706"	"ADRM1"	"A0PKB1; hsa:11047; Q16186; Q96FJ7; Q9H1P2"	"Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Ub-specific processing proteases; UCH proteinases"	"4"	"0"	"54.5"	"188.7"	"192.8"	"48.8"	"120.1"	"65.3"	"76.3"	"57.3"	"96.0"	"115.4"	"201.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14331"	"Protein FRG1 OS=Homo sapiens OX=9606 GN=FRG1 PE=1 SV=1"	"5"	"1"	"2"	"1"	"258"	"29.2"	"9.01"	"542.26"	"3.22"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus"	"cytoskeletal activity"	"Pf06229"	"2483"	"ENSG00000109536; ENSG00000275145; ENSG00000283153; ENSG00000283630"	"FRG1"	"A8K775; hsa:2483; Q14331"	""	""	"0"	"0"	"33.1"	"60.1"	"72.7"	"29.1"	"52.3"	"31.2"	"66.3"	"65.2"	"126.3"	"206.9"	"397.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5TFE4"	"5'-nucleotidase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=NT5DC1 PE=1 SV=1"	"3"	"1"	"2"	"1"	"455"	"51.8"	"6.35"	"344.25"	"3.22"	"1"	"1"	""	""	"other molecular function"	"Pf05761"	"221294"	"ENSG00000178425"	"NT5DC1"	"B2RND9; B3KR35; hsa:221294; Q5TFE4; Q6XYD5"	""	""	"0"	"0"	"22.7"	"88.0"	"62.4"	"11.8"	"63.3"	"19.6"	"29.6"	"32.4"	"33.9"	"38.2"	"69.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQ24"	"Zinc finger FYVE domain-containing protein 21 OS=Homo sapiens OX=9606 GN=ZFYVE21 PE=1 SV=1"	"7"	"1"	"2"	"1"	"234"	"26.5"	"8.41"	"361.30"	"3.22"	"1"	"1"	""	"other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01363, Pf16696"	"79038"	"ENSG00000100711"	"ZFYVE21"	"A8K3A4; hsa:79038; Q86T05; Q96LT1; Q9BQ24"	""	""	"0"	"0"	"3.6"	"12.0"	"11.1"	"3.8"	"9.7"	"8.0"	"11.9"	"12.7"	"21.3"	"28.6"	"52.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P00387"	"NADH-cytochrome b5 reductase 3 OS=Homo sapiens OX=9606 GN=CYB5R3 PE=1 SV=3"	"4"	"1"	"2"	"1"	"301"	"34.2"	"7.59"	"348.49"	"3.22"	"1"	"1"	"other metabolic processes;other biological processes"	"non-structural extracellular;other membranes;cytosol;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00175, Pf00970"	"1727"	"ENSG00000100243"	"CYB5R3"	"B1AHF2; B7Z7L3; hsa:1727; O75675; P00387; Q8TDL8; Q8WTS8; Q9UEN4; Q9UEN5; Q9UL55; Q9UL56"	"Oxidation by cytochrome P450"	"Phase I - Functionalization of compounds; Neutrophil degranulation; Vitamin C (ascorbate) metabolism"	"4"	"0"	"13.7"	"69.2"	"58.4"	"13.3"	"46.1"	"17.1"	"31.7"	"20.6"	"42.5"	"68.4"	"138.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5TBB1"	"Ribonuclease H2 subunit B OS=Homo sapiens OX=9606 GN=RNASEH2B PE=1 SV=1"	"6"	"2"	"3"	"2"	"312"	"35.1"	"9.13"	"789.37"	"3.22"	"2"	"1"	"cell cycle OR cell proliferation;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	""	"Pf09468, Pf17745"	"79621"	"ENSG00000136104"	"RNASEH2B"	"G3XAJ1; hsa:79621; Q05DR2; Q5TBB1; Q6PK48; Q9HAF7"	""	""	"0"	"0"	"24.4"	"70.7"	"65.9"	"24.2"	"52.8"	"30.1"	"100.9"	"83.2"	"127.8"	"133.4"	"175.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UJS0"	"Calcium-binding mitochondrial carrier protein Aralar2 OS=Homo sapiens OX=9606 GN=SLC25A13 PE=1 SV=2"	"3"	"1"	"3"	"1"	"675"	"74.1"	"8.62"	"739.96"	"3.21"	"1"	"1"	"other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00153"	"10165"	"ENSG00000004864"	"SLC25A13"	"hsa:10165; O14566; O14575; Q546F9; Q9NZW1; Q9UJS0; Q9UNI7"	""	"Gluconeogenesis; Mitochondrial protein import; Aspartate and asparagine metabolism"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IYB5"	"Stromal membrane-associated protein 1 OS=Homo sapiens OX=9606 GN=SMAP1 PE=1 SV=2"	"4"	"2"	"3"	"2"	"467"	"50.4"	"8.75"	"589.25"	"3.20"	"2"	"1"	"other biological processes"	"plasma membrane;other membranes;other cell component"	"enzyme regulator activity;other molecular function"	"Pf01412"	"60682"	"ENSG00000112305"	"SMAP1"	"hsa:60682; Q53H70; Q5SYQ2; Q6PK24; Q8IYB5; Q8NDH4; Q96L38; Q96L39; Q9H8X4"	""	""	"0"	"0"	"156.5"	"175.9"	"195.8"	"109.4"	"209.9"	"140.1"	"254.4"	"151.8"	"229.5"	"216.0"	"291.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q03252"	"Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4"	"1"	"1"	"2"	"1"	"620"	"69.9"	"5.59"	"268.06"	"3.20"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytoskeleton;nucleus"	"cytoskeletal activity;other molecular function"	"Pf00038, Pf00932"	"84823"	"ENSG00000176619"	"LMNB2"	"hsa:84823; O75292; Q03252; Q14734; Q96DF6"	"Gastric cancer network 2; Fas ligand pathway and stress induction of heat shock proteins; IL-18 signaling pathway; Familial partial lipodystrophy; Progeria-associated lipodystrophy; Acquired partial lipodystrophy / Barraquer-Simons syndrome"	""	"6"	"0"	"4.9"	"30.8"	"30.6"	"5.2"	"22.4"	"11.5"	"15.6"	"13.9"	"27.2"	"40.0"	"52.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UL25"	"Ras-related protein Rab-21 OS=Homo sapiens OX=9606 GN=RAB21 PE=1 SV=3"	"5"	"1"	"2"	"1"	"225"	"24.3"	"7.94"	"370.02"	"3.20"	"1"	"1"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00071"	"23011"	"ENSG00000080371"	"RAB21"	"hsa:23011; Q14466; Q569H3; Q9UL25"	"Ciliary landscape"	"RAB GEFs exchange GTP for GDP on RABs; RAB geranylgeranylation"	"3"	"0"	"20.3"	"64.4"	"57.3"	"18.0"	"54.2"	"26.4"	"38.4"	"30.8"	"35.0"	"47.2"	"74.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15446"	"DNA-directed RNA polymerase I subunit RPA34 OS=Homo sapiens OX=9606 GN=CD3EAP PE=1 SV=1"	"2"	"1"	"2"	"1"	"510"	"55.0"	"8.51"	"302.09"	"3.20"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;signal transduction"	"cytosol;mitochondrion;nucleus;other cell component"	""	"Pf08208"	"10849"	"ENSG00000117877"	"POLR1G"	"hsa:10849; O15446; Q32N11; Q7Z5U2; Q9UPF6"	"2q13 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"6"	"0"	"7.4"	"16.8"	"15.9"	"7.6"	"16.2"	"16.0"	"20.4"	"27.7"	"90.8"	"121.0"	"154.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13144"	"Translation initiation factor eIF-2B subunit epsilon OS=Homo sapiens OX=9606 GN=EIF2B5 PE=1 SV=3"	"2"	"1"	"2"	"1"	"721"	"80.3"	"5.08"	"365.54"	"3.20"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf02020"	"8893"	"ENSG00000145191"	"EIF2B5"	"hsa:8893; Q13144; Q541Z1; Q96D04"	"Translation factors; MicroRNAs in cardiomyocyte hypertrophy; DYRK1A involvement regarding cell proliferation in brain development; Primary ovarian insufficiency"	"Recycling of eIF2:GDP"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00541"	"Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1"	"2"	"1"	"2"	"1"	"588"	"68.0"	"7.33"	"345.75"	"3.19"	"1"	"1"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf06732, Pf16589"	"23481"	"ENSG00000100029"	"PES1"	"hsa:23481; O00541; Q6IC29"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"21.3"	"47.1"	"52.9"	"9.9"	"39.3"	"21.8"	"41.5"	"30.6"	"46.0"	"50.4"	"91.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94760"	"N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 OS=Homo sapiens OX=9606 GN=DDAH1 PE=1 SV=3"	"5"	"1"	"1"	"1"	"285"	"31.1"	"5.81"	""	"3.19"	""	"1"	"other metabolic processes;signal transduction;other biological processes"	"cytosol"	"other molecular function"	"Pf02274"	"23576"	"ENSG00000153904"	"DDAH1"	"hsa:23576; O94760; Q5HYC8; Q86XK5"	"Mesodermal commitment pathway; Nitric oxide metabolism in cystic fibrosis"	"eNOS activation"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96I25"	"Splicing factor 45 OS=Homo sapiens OX=9606 GN=RBM17 PE=1 SV=1"	"4"	"1"	"2"	"1"	"401"	"44.9"	"5.97"	"336.38"	"3.19"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf01585"	"84991"	"ENSG00000134453"	"RBM17"	"hsa:84991; Q96GY6; Q96I25"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96FZ2"	"Abasic site processing protein HMCES OS=Homo sapiens OX=9606 GN=HMCES PE=1 SV=1"	"3"	"1"	"2"	"1"	"354"	"40.5"	"8.15"	"326.47"	"3.19"	"1"	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02586"	"56941"	"ENSG00000183624"	"HMCES"	"A6NJR9; hsa:56941; Q96FZ2; Q96G34; Q9NRP3"	""	""	"0"	"0"	"11.4"	"32.7"	"29.3"	"15.1"	"27.5"	"12.7"	"29.8"	"27.6"	"33.2"	"37.7"	"56.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49903"	"Selenide, water dikinase 1 OS=Homo sapiens OX=9606 GN=SEPHS1 PE=1 SV=2"	"5"	"1"	"1"	"1"	"392"	"42.9"	"5.97"	""	"3.18"	""	"1"	"protein metabolism;other metabolic processes"	"plasma membrane;other membranes;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00586, Pf02769"	"22929"	"ENSG00000086475"	"SEPHS1"	"B4DWK0; D3DRS9; D6PSQ9; hsa:22929; P49903; Q5T5U8; Q5T5U9; Q9BVT4"	""	""	"0"	"0"	"15.9"	"55.0"	"50.2"	"19.2"	"49.0"	"16.8"	"38.1"	"20.1"	"37.4"	"46.7"	"71.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14919"	"Dr1-associated corepressor OS=Homo sapiens OX=9606 GN=DRAP1 PE=1 SV=3"	"5"	"1"	"2"	"1"	"205"	"22.3"	"5.17"	"349.59"	"3.18"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00808"	"10589"	"ENSG00000175550"	"DRAP1"	"hsa:10589; Q13448; Q14919"	""	"Signaling by NODAL; Signaling by Activin"	"2"	"0"	"37.1"	"145.3"	"111.5"	"27.9"	"85.1"	"41.2"	"65.0"	"42.4"	"61.1"	"82.2"	"157.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13674"	"Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2"	"3"	"1"	"2"	"1"	"534"	"61.0"	"6.01"	"331.92"	"3.18"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"ER/Golgi;other cell component"	"other molecular function"	"Pf08336, Pf13640"	"5033"	"ENSG00000122884"	"P4HA1"	"C9JL12; hsa:5033; P13674; Q15082; Q15083; Q5VSQ5"	"Type I collagen synthesis in the context of osteogenesis imperfecta"	"Collagen biosynthesis and modifying enzymes"	"2"	"0"	"14.2"	"44.2"	"40.3"	"14.0"	"41.0"	"18.3"	"29.2"	"24.4"	"47.1"	"47.7"	"73.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12824"	"SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 OS=Homo sapiens OX=9606 GN=SMARCB1 PE=1 SV=2"	"4"	"1"	"2"	"1"	"385"	"44.1"	"6.23"	"351.25"	"3.17"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04855"	"6598"	"ENSG00000099956; ENSG00000275837"	"SMARCB1"	"hsa:6598; O75784; O95474; Q12824; Q17S11; Q38GA1; Q76N08; Q9UBH2"	"Tumor suppressor activity of SMARCB1; Thermogenesis; Modulators of TCR signaling and T cell activation; DYRK1A involvement regarding cell proliferation in brain development; Kleefstra syndrome"	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; RMTs methylate histone arginines"	"7"	"0"	"20.6"	"36.3"	"40.6"	"17.4"	"37.2"	"25.2"	"51.6"	"44.1"	"59.4"	"69.2"	"94.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NF91"	"Nesprin-1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=4"	"0"	"2"	"2"	"1"	"8797"	"1010.5"	"5.53"	"252.75"	"3.16"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00435, Pf10541"	"23345"	"ENSG00000131018"	"SYNE1"	"B3W695; E7EQI5; H0Y4C0; hsa:23345; O94890; Q3ZCV0; Q5JV19; Q5JV22; Q8N9P7; Q8NF91; Q8TCP1; Q8WWW6; Q8WWW7; Q8WXF6; Q96N17; Q9C0A7; Q9H525; Q9H526; Q9NS36; Q9NU50; Q9UJ06; Q9UJ07; Q9ULF8"	"Envelope proteins and their potential roles in EDMD physiopathology"	"Meiotic synapsis"	"2"	"0"	"10.5"	"58.5"	"39.7"	"7.3"	"45.2"	"15.4"	"18.3"	"13.4"	"25.6"	"39.6"	"128.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00401"	"Neural Wiskott-Aldrich syndrome protein OS=Homo sapiens OX=9606 GN=WASL PE=1 SV=2"	"2"	"1"	"2"	"1"	"505"	"54.8"	"7.93"	"364.21"	"3.15"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity"	"Pf00568, Pf00786, Pf02205"	"8976"	"ENSG00000106299"	"WASL"	"A1JUI9; hsa:8976; O00401; Q7Z746"	"Pathogenic Escherichia coli infection; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; Chemokine signaling pathway; G13 signaling pathway"	"Clathrin-mediated endocytosis; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RHO GTPases Activate WASPs and WAVEs; RHOJ GTPase cycle; RHOV GTPase cycle; NOSTRIN mediated eNOS trafficking; Nephrin family interactions; EPHB-mediated forward signaling; DCC mediated attractive signaling"	"17"	"0"	"48.3"	"97.4"	"108.5"	"43.0"	"85.2"	"55.9"	"107.4"	"100.0"	"150.4"	"215.6"	"358.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q93084"	"Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 OS=Homo sapiens OX=9606 GN=ATP2A3 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1043"	"113.9"	"5.57"	"270.13"	"3.15"	"1"	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"71.8"	"225.3"	"194.3"	"66.7"	"183.4"	"87.5"	"119.0"	"81.8"	"120.6"	"184.1"	"289.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14859"	"POU domain, class 2, transcription factor 1 OS=Homo sapiens OX=9606 GN=POU2F1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"743"	"76.4"	"6.81"	"421.52"	"3.15"	"1"	"1"	"RNA metabolism OR transcription;other biological processes"	"ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00046, Pf00157, Pf19536"	"5451"	"ENSG00000143190"	"POU2F1"	"B1AL91; B1AL93; B4E029; hsa:5451; J3KP77; P14859; Q5TBT7; Q6PK46; Q8NEU9; Q9BPV1"	"Integrated cancer pathway"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 3 Promoter; RNA polymerase II transcribes snRNA genes; Estrogen-dependent gene expression; Interleukin-4 and Interleukin-13 signaling"	"6"	"0"	"8.7"	"30.5"	"25.2"	"4.7"	"23.1"	"11.9"	"16.2"	"12.0"	"23.4"	"28.8"	"37.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NWU1"	"3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial OS=Homo sapiens OX=9606 GN=OXSM PE=1 SV=1"	"3"	"1"	"2"	"1"	"459"	"48.8"	"7.66"	"339.08"	"3.14"	"1"	"1"	"other metabolic processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf00109, Pf02801"	"54995"	"ENSG00000151093"	"OXSM"	"hsa:54995; Q9NWU1"	"Mitochondrial fatty acid synthesis pathway"	""	"1"	"0"	"10.8"	"26.0"	"27.0"	"6.7"	"26.4"	"9.1"	"12.2"	"15.3"	"30.2"	"59.5"	"125.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31025"	"Lipocalin-1 OS=Homo sapiens OX=9606 GN=LCN1 PE=1 SV=1"	"6"	"1"	"2"	"1"	"176"	"19.2"	"5.58"	"380.38"	"3.14"	"1"	"1"	"protein metabolism;other biological processes"	"non-structural extracellular"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00061"	"3933"	"ENSG00000160349"	"LCN1"	"hsa:3933; P31025; Q5T8A1"	""	"Transport of fatty acids"	"1"	"0"	"48.9"	"90.1"	"93.5"	"34.6"	"81.8"	"44.4"	"99.0"	"81.1"	"103.4"	"121.6"	"180.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P17096"	"High mobility group protein HMG-I/HMG-Y OS=Homo sapiens OX=9606 GN=HMGA1 PE=1 SV=3"	"23"	"2"	"4"	"2"	"107"	"11.7"	"10.32"	"1545.29"	"3.14"	"2"	"1"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	""	"3159"	"ENSG00000137309"	"HMGA1"	"hsa:3159; P10910; P17096; Q5T6U9; Q9UKB0"	"Adipogenesis; Pre-implantation embryo; Male infertility; 7q11.23 copy number variation syndrome; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Orexin receptor pathway"	"Vpr-mediated nuclear import of PICs; 2-LTR circle formation; Integration of viral DNA into host genomic DNA; Autointegration results in viral DNA circles; APOBEC3G mediated resistance to HIV-1 infection; Formation of Senescence-Associated Heterochromatin Foci (SAHF)"	"13"	"0"	"112.9"	"182.8"	"200.0"	"96.3"	"177.1"	"113.4"	"342.4"	"260.0"	"365.3"	"428.5"	"623.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86TU7"	"Actin-histidine N-methyltransferase OS=Homo sapiens OX=9606 GN=SETD3 PE=1 SV=1"	"2"	"1"	"2"	"1"	"594"	"67.2"	"5.96"	"357.48"	"3.13"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00856, Pf09273"	"84193"	"ENSG00000183576"	"SETD3"	"A0PJU3; A5PLP0; B4DZE8; hsa:84193; Q0VAQ2; Q659C0; Q86TU7; Q86TU8; Q96GY9; Q9H5U5"	"Histone modifications"	"PKMTs methylate histone lysines"	"2"	"0"	"7.0"	"19.6"	"20.9"	"8.8"	"16.9"	"9.5"	"55.7"	"41.0"	"54.0"	"72.6"	"137.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96FW1"	"Ubiquitin thioesterase OTUB1 OS=Homo sapiens OX=9606 GN=OTUB1 PE=1 SV=2"	"4"	"1"	"2"	"1"	"271"	"31.3"	"4.94"	"367.17"	"3.12"	"1"	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf10275"	"55611"	"ENSG00000167770"	"OTUB1"	"hsa:55611; Q32Q78; Q96FW1; Q96II3; Q9NXQ4; Q9P0B8"	""	"Ub-specific processing proteases; Ovarian tumor domain proteases"	"2"	"0"	"27.2"	"114.3"	"101.3"	"19.2"	"90.1"	"29.4"	"43.3"	"32.3"	"46.1"	"61.6"	"88.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NVP1"	"ATP-dependent RNA helicase DDX18 OS=Homo sapiens OX=9606 GN=DDX18 PE=1 SV=2"	"2"	"1"	"2"	"1"	"670"	"75.4"	"9.50"	"496.57"	"3.12"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271, Pf13959"	"8886"	"ENSG00000088205"	"DDX18"	"hsa:8886; Q6GTZ9; Q6IAU4; Q92732; Q9BQB7; Q9NVP1"	""	""	"0"	"0"	"21.5"	"31.4"	"43.6"	"22.0"	"41.2"	"30.4"	"73.9"	"59.7"	"94.6"	"85.8"	"121.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75663"	"TIP41-like protein OS=Homo sapiens OX=9606 GN=TIPRL PE=1 SV=2"	"3"	"1"	"2"	"1"	"272"	"31.4"	"5.91"	"388.58"	"3.11"	"1"	"1"	"stress response;signal transduction;other biological processes"	"cytosol"	""	"Pf04176"	"261726"	"ENSG00000143155"	"TIPRL"	"B2R8V3; hsa:261726; O75663; Q5HYB2; Q8IZ86"	"Ciliary landscape"	""	"1"	"0"	"95.6"	"269.7"	"259.6"	"79.8"	"233.1"	"125.0"	"163.5"	"136.6"	"187.1"	"210.0"	"346.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99536"	"Synaptic vesicle membrane protein VAT-1 homolog OS=Homo sapiens OX=9606 GN=VAT1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"393"	"41.9"	"6.29"	"288.85"	"3.10"	"1"	"1"	"other biological processes"	"non-structural extracellular;other membranes;mitochondrion;other cytoplasmic organelle"	"other molecular function"	"Pf08240, Pf13602"	"10493"	"ENSG00000108828"	"VAT1"	"A8K345; B0AZP7; B4DPX4; hsa:10493; Q13035; Q5BKZ7; Q96A39; Q99536; Q9BUT8"	""	"Neutrophil degranulation"	"1"	"0"	"43.2"	"150.1"	"159.9"	"47.1"	"148.6"	"52.1"	"88.9"	"61.6"	"98.2"	"125.2"	"215.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96TA2"	"ATP-dependent zinc metalloprotease YME1L1 OS=Homo sapiens OX=9606 GN=YME1L1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"773"	"86.4"	"8.76"	"287.73"	"3.10"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf00004, Pf01434, Pf17862"	"10730"	"ENSG00000136758"	"YME1L1"	"B4DNM1; D3DRV8; D3DRV9; hsa:10730; Q5T8D9; Q96TA2; Q9H1Q0; Q9UMR9"	""	"Processing of SMDT1"	"1"	"0"	"13.2"	"32.0"	"23.3"	"9.4"	"20.3"	"14.9"	"29.9"	"13.2"	"24.5"	"31.7"	"49.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96MX6"	"WD repeat-containing protein 92 OS=Homo sapiens OX=9606 GN=WDR92 PE=1 SV=1"	"4"	"2"	"3"	"2"	"357"	"39.7"	"8.09"	"541.78"	"3.10"	"2"	"1"	"cell organization and biogenesis;other biological processes"	"other cell component"	"other molecular function"	"Pf00400"	"116143"	"ENSG00000243667"	"DNAAF10"	"hsa:116143; Q96CR6; Q96MX6"	""	""	"0"	"0"	"86.0"	"197.1"	"197.1"	"87.6"	"198.4"	"103.2"	"234.2"	"209.3"	"270.9"	"344.1"	"523.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BS26"	"Endoplasmic reticulum resident protein 44 OS=Homo sapiens OX=9606 GN=ERP44 PE=1 SV=1"	"4"	"1"	"2"	"1"	"406"	"46.9"	"5.26"	"281.30"	"3.10"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf00085, Pf13848"	"23071"	"ENSG00000023318"	"ERP44"	"hsa:23071; O60319; Q4VXC1; Q5VWZ7; Q6UW14; Q8WX67; Q9BS26"	""	"Neutrophil degranulation"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52701"	"DNA mismatch repair protein Msh6 OS=Homo sapiens OX=9606 GN=MSH6 PE=1 SV=2"	"1"	"2"	"3"	"2"	"1360"	"152.7"	"6.90"	"546.77"	"3.09"	"2"	"1"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00488, Pf00855, Pf01624, Pf05188, Pf05190, Pf05192"	"2956"	"ENSG00000116062"	"MSH6"	"B4DF41; B4E3I4; F5H2F9; hsa:2956; O43706; O43917; P52701; Q8TCX4; Q9BTB5"	"Glioblastoma signaling pathways; Retinoblastoma gene in cancer; Chromosomal and microsatellite instability in colorectal cancer ; DNA repair pathways, full network; DNA mismatch repair"	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Defective Mismatch Repair Associated With MSH2; Defective Mismatch Repair Associated With MSH6"	"8"	"0"	"86.0"	"226.7"	"200.6"	"63.8"	"161.4"	"93.0"	"149.4"	"128.7"	"163.2"	"240.4"	"380.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P52294"	"Importin subunit alpha-5 OS=Homo sapiens OX=9606 GN=KPNA1 PE=1 SV=3"	"2"	"1"	"1"	"1"	"538"	"60.2"	"5.01"	""	"3.09"	""	"1"	"cell-cell signaling;cell cycle OR cell proliferation;transport;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00514, Pf01749, Pf16186"	"3836"	"ENSG00000114030"	"KPNA1"	"D3DN93; hsa:3836; P52294; Q6IBQ9; Q9BQ56"	"Ebola virus infection in host"	"Assembly of the ORC complex at the origin of replication; ISG15 antiviral mechanism; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Vpr-mediated nuclear import of PICs; Apoptosis induced DNA fragmentation; Interferon alpha/beta signaling; Integration of provirus; Inhibition of nitric oxide production"	"10"	"0"	"76.9"	"142.4"	"127.2"	"74.4"	"186.9"	"114.2"	"182.0"	"161.8"	"186.9"	"243.4"	"340.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30626"	"Sorcin OS=Homo sapiens OX=9606 GN=SRI PE=1 SV=1"	"6"	"1"	"2"	"1"	"198"	"21.7"	"5.59"	"284.17"	"3.08"	"1"	"1"	"transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf13405, Pf13833"	"6717"	"ENSG00000075142"	"SRI"	"A8MTH6; B4DKK2; D6W5Q0; hsa:6717; P30626"	""	"Stimuli-sensing channels; Ion homeostasis; Ion transport by P-type ATPases; Reduction of cytosolic Ca++ levels; Sodium/Calcium exchangers"	"5"	"0"	"5.7"	"33.3"	"32.0"	"6.0"	"17.9"	"7.8"	"6.6"	"10.7"	"12.6"	"13.5"	"22.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N5K1"	"CDGSH iron-sulfur domain-containing protein 2 OS=Homo sapiens OX=9606 GN=CISD2 PE=1 SV=1"	"10"	"1"	"2"	"1"	"135"	"15.3"	"9.61"	"400.35"	"3.07"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"other membranes;mitochondrion;ER/Golgi;other cell component"	"other molecular function"	"Pf09360, Pf10660"	"493856"	"ENSG00000145354"	"CISD2"	"hsa:493856; Q7Z3D5; Q8N5K1"	""	""	"0"	"0"	"9.2"	"19.4"	"23.9"	"7.8"	"27.4"	"8.8"	"17.6"	"10.9"	"16.0"	"25.0"	"40.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H7E9"	"UPF0488 protein C8orf33 OS=Homo sapiens OX=9606 GN=C8orf33 PE=1 SV=1"	"7"	"1"	"2"	"1"	"229"	"25.0"	"9.95"	"292.75"	"3.07"	"1"	"1"	""	""	""	"Pf15393"	"65265"	"ENSG00000182307"	"C8orf33"	"A6NGC0; hsa:65265; Q96BT8; Q9H7E9"	""	""	"0"	"0"	"17.5"	"35.5"	"41.4"	"21.2"	"41.6"	"24.8"	"44.5"	"39.3"	"43.9"	"60.9"	"90.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NBJ5"	"Procollagen galactosyltransferase 1 OS=Homo sapiens OX=9606 GN=COLGALT1 PE=1 SV=1"	"2"	"1"	"2"	"1"	"622"	"71.6"	"7.31"	"361.03"	"3.07"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"ER/Golgi"	"other molecular function"	"Pf01755, Pf13704"	"79709"	"ENSG00000130309"	"COLGALT1"	"hsa:79709; Q8NBJ5; Q8NC64"	"Type I collagen synthesis in the context of osteogenesis imperfecta"	"Collagen biosynthesis and modifying enzymes"	"2"	"0"	"48.6"	"112.8"	"108.3"	"41.3"	"115.3"	"51.0"	"104.3"	"101.1"	"125.6"	"168.5"	"256.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UNZ2"	"NSFL1 cofactor p47 OS=Homo sapiens OX=9606 GN=NSFL1C PE=1 SV=2"	"3"	"1"	"2"	"1"	"370"	"40.5"	"5.10"	"325.93"	"3.07"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00789, Pf08059, Pf14555"	"55968"	"ENSG00000088833"	"NSFL1C"	"A2A2L1; B2RD74; hsa:55968; Q5JXA4; Q5JXA5; Q7Z533; Q9H102; Q9NVL9; Q9UI06; Q9UNZ2"	"Alstrom syndrome"	"RHOH GTPase cycle"	"2"	"0"	"28.1"	"61.7"	"59.5"	"21.1"	"62.6"	"27.7"	"44.8"	"34.9"	"45.9"	"51.0"	"75.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75531"	"Barrier-to-autointegration factor OS=Homo sapiens OX=9606 GN=BANF1 PE=1 SV=1"	"13"	"1"	"2"	"1"	"89"	"10.1"	"6.09"	"397.37"	"3.07"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02961"	"8815"	"ENSG00000175334"	"BANF1"	"hsa:8815; O60558; O75531; Q6FGG7"	"Envelope proteins and their potential roles in EDMD physiopathology; Familial partial lipodystrophy; Progeria-associated lipodystrophy"	"Vpr-mediated nuclear import of PICs; 2-LTR circle formation; Integration of viral DNA into host genomic DNA; Autointegration results in viral DNA circles; APOBEC3G mediated resistance to HIV-1 infection; Nuclear Envelope Breakdown; Initiation of Nuclear Envelope (NE) Reformation"	"11"	"0"	"17.6"	"79.6"	"61.9"	"8.7"	"51.6"	"23.9"	"45.4"	"35.0"	"45.7"	"81.7"	"99.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04179"	"Superoxide dismutase [Mn], mitochondrial OS=Homo sapiens OX=9606 GN=SOD2 PE=1 SV=3"	"6"	"1"	"2"	"1"	"222"	"24.7"	"8.25"	"424.12"	"3.07"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00081, Pf02777"	"6648"	"ENSG00000291237"	"SOD2"	"B2R7R1; B3KUK2; B4DL20; B4E3K9; E1P5A9; hsa:6648; P04179; P78434; Q16792; Q5TCM1; Q96EE6; Q9P2Z3"	"Selenium micronutrient network; Vitamin B12 metabolism; Folate metabolism; VEGFA-VEGFR2 signaling; Oxidative stress response"	"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Detoxification of Reactive Oxygen Species; Transcriptional activation of mitochondrial biogenesis; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"	"10"	"0"	"30.3"	"129.2"	"116.0"	"25.7"	"99.8"	"34.8"	"59.5"	"50.5"	"58.6"	"89.4"	"168.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75448"	"Mediator of RNA polymerase II transcription subunit 24 OS=Homo sapiens OX=9606 GN=MED24 PE=1 SV=1"	"2"	"1"	"2"	"1"	"989"	"110.2"	"6.95"	"343.72"	"3.06"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf11277"	"9862"	"ENSG00000008838"	"MED24"	"A8K4S5; B3KMR9; hsa:9862; O75448; Q14143; Q9NNY5"	""	"PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; Generic Transcription Pathway"	"3"	"0"	"10.9"	"12.2"	"20.1"	"5.7"	"20.3"	"8.6"	"12.9"	"10.2"	"17.1"	"26.8"	"30.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P2E9"	"Enhancer of mRNA-decapping protein 4 OS=Homo sapiens OX=9606 GN=EDC4 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1401"	"151.6"	"5.86"	"269.08"	"3.06"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf16529"	"23644"	"ENSG00000038358"	"EDC4"	"A6NGM1; A8K4T4; hsa:23644; Q13025; Q13826; Q6P2E9; Q6ZR12; Q7Z6H7"	""	"mRNA decay by 5' to 3' exoribonuclease"	"1"	"0"	"19.1"	"49.6"	"49.7"	"22.2"	"57.0"	"33.1"	"44.1"	"36.6"	"41.5"	"70.7"	"90.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P16278"	"Beta-galactosidase OS=Homo sapiens OX=9606 GN=GLB1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"677"	"76.0"	"6.57"	"300.96"	"3.06"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01301, Pf13364"	"2720"	"ENSG00000170266"	"GLB1"	"B2R7H8; B7Z6B0; hsa:2720; P16278; P16279"	"Ectoderm differentiation; Degradation pathway of sphingolipids, including diseases; Ciliary landscape; Glycosaminoglycan degradation; Sphingolipid metabolism in senescence"	"Neutrophil degranulation; Glycosphingolipid metabolism; HS-GAG degradation; Sialic acid metabolism; Keratan sulfate degradation; Defective NEU1 causes sialidosis; MPS IV - Morquio syndrome B"	"12"	"0"	"13.6"	"34.3"	"35.3"	"10.6"	"31.7"	"22.6"	"18.2"	"11.8"	"16.9"	"25.7"	"38.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BZZ5"	"Apoptosis inhibitor 5 OS=Homo sapiens OX=9606 GN=API5 PE=1 SV=3"	"4"	"2"	"3"	"2"	"524"	"59.0"	"7.34"	"570.75"	"3.06"	"2"	"1"	"other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf05918"	"8539"	"ENSG00000166181"	"API5"	"B4DGR0; B4DRJ2; B4E283; D3DR21; G3V1C3; hsa:8539; O15441; Q9BZZ5; Q9Y4J7"	""	""	"0"	"0"	"58.5"	"168.1"	"171.6"	"48.2"	"153.1"	"73.0"	"133.9"	"95.4"	"124.7"	"191.0"	"285.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6ZXV5"	"Protein O-mannosyl-transferase TMTC3 OS=Homo sapiens OX=9606 GN=TMTC3 PE=1 SV=2"	"1"	"1"	"1"	"1"	"915"	"103.9"	"8.87"	""	"3.06"	""	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf08409, Pf13174, Pf13181, Pf13431"	"160418"	"ENSG00000139324"	"TMTC3"	"hsa:160418; Q5CZ86; Q5H9T6; Q68DQ6; Q68DX0; Q6ZXV5; Q7Z332; Q8NC50"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H7C9"	"Mth938 domain-containing protein OS=Homo sapiens OX=9606 GN=AAMDC PE=1 SV=1"	"9"	"1"	"2"	"1"	"122"	"13.3"	"8.46"	"349.46"	"3.06"	"1"	"1"	"other biological processes"	"other cell component"	""	"Pf04430"	"28971"	"ENSG00000087884"	"AAMDC"	"hsa:28971; Q96AQ4; Q9H7C9; Q9Y6B1"	""	""	"0"	"0"	"88.6"	"140.4"	"146.8"	"78.2"	"133.4"	"78.7"	"114.7"	"85.6"	"118.6"	"131.3"	"228.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62314"	"Small nuclear ribonucleoprotein Sm D1 OS=Homo sapiens OX=9606 GN=SNRPD1 PE=1 SV=1"	"17"	"1"	"2"	"1"	"119"	"13.3"	"11.56"	"243.12"	"3.06"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01423"	"6632"	"ENSG00000167088"	"SNRPD1"	"B5BTZ1; hsa:6632; P13641; P62314"	"mRNA processing"	"mRNA Splicing - Major Pathway; SARS-CoV-2 modulates host translation machinery; snRNP Assembly; mRNA Splicing - Minor Pathway"	"5"	"0"	"2.2"	"22.0"	"10.3"	"4.1"	"4.5"	"3.4"	"10.8"	"20.2"	"18.6"	"23.9"	"31.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q02880"	"DNA topoisomerase 2-beta OS=Homo sapiens OX=9606 GN=TOP2B PE=1 SV=3"	"2"	"3"	"5"	"3"	"1626"	"183.2"	"8.00"	"940.10"	"3.05"	"3"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00204, Pf00521, Pf01751, Pf02518, Pf08070, Pf16898"	"7155"	"ENSG00000077097"	"TOP2B"	"hsa:7155; Q02880; Q13600; Q9UMG8; Q9UQP8"	""	"SUMOylation of DNA replication proteins"	"1"	"0"	"107.1"	"186.4"	"195.8"	"75.9"	"179.0"	"99.3"	"176.1"	"134.8"	"194.0"	"210.9"	"314.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55199"	"RNA polymerase II elongation factor ELL OS=Homo sapiens OX=9606 GN=ELL PE=1 SV=1"	"5"	"2"	"3"	"2"	"621"	"68.2"	"9.33"	"721.29"	"3.05"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf07303, Pf10390"	"8178"	"ENSG00000105656"	"ELL"	"hsa:8178; P55199"	"Interactome of polycomb repressive complex 2 (PRC2)"	"Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; RNA polymerase II transcribes snRNA genes; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; TP53 Regulates Transcription of DNA Repair Genes; Transcription-Coupled Nucleotide Excision Repair (TC-NER)"	"14"	"0"	"3.0"	"6.2"	"3.7"	"2.7"	"6.6"	"2.0"	"16.5"	"10.7"	"12.0"	"21.0"	"33.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5M8"	"Signal recognition particle receptor subunit beta OS=Homo sapiens OX=9606 GN=SRPRB PE=1 SV=3"	"4"	"1"	"1"	"1"	"271"	"29.7"	"9.04"	""	"3.04"	""	"1"	"cell organization and biogenesis;transport"	"other membranes;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf09439"	"58477"	"ENSG00000144867"	"SRPRB"	"hsa:58477; Q6P595; Q8N2D8; Q9Y5M8"	""	"SRP-dependent cotranslational protein targeting to membrane; XBP1(S) activates chaperone genes"	"2"	"0"	"27.5"	"76.1"	"67.9"	"32.6"	"73.7"	"37.2"	"59.8"	"45.4"	"56.6"	"77.7"	"114.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BV57"	"1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase OS=Homo sapiens OX=9606 GN=ADI1 PE=1 SV=1"	"12"	"2"	"3"	"2"	"179"	"21.5"	"5.68"	"641.03"	"3.04"	"2"	"1"	"other metabolic processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf03079"	"55256"	"ENSG00000182551"	"ADI1"	"D6W4Y3; hsa:55256; Q53HW3; Q53QD3; Q57YV7; Q68CK2; Q6ZSF7; Q7Z512; Q96P85; Q9BV57; Q9NV57"	"Methionine de novo and salvage pathway"	"Methionine salvage pathway"	"2"	"0"	"128.0"	"365.1"	"370.6"	"86.3"	"305.0"	"132.5"	"201.0"	"153.2"	"207.7"	"277.8"	"458.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92504"	"Zinc transporter SLC39A7 OS=Homo sapiens OX=9606 GN=SLC39A7 PE=1 SV=2"	"3"	"1"	"2"	"1"	"469"	"50.1"	"6.87"	"354.94"	"3.04"	"1"	"1"	"transport;other biological processes"	"other membranes;ER/Golgi;nucleus"	"transporter activity"	"Pf02535"	"7922"	"ENSG00000112473; ENSG00000206288; ENSG00000224399; ENSG00000226614; ENSG00000227402; ENSG00000229802"	"SLC39A7"	"B0UXF6; hsa:7922; Q5STP8; Q92504; Q9UIQ0"	"Nuclear receptors meta-pathway; NRF2 pathway; Zinc homeostasis"	"Zinc influx into cells by the SLC39 gene family"	"4"	"0"	"76.0"	"130.5"	"144.4"	"70.4"	"174.4"	"110.2"	"127.3"	"66.4"	"131.7"	"178.0"	"199.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51965"	"Ubiquitin-conjugating enzyme E2 E1 OS=Homo sapiens OX=9606 GN=UBE2E1 PE=1 SV=1"	"9"	"1"	"1"	"1"	"193"	"21.4"	"8.53"	""	"3.03"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00179"	"7324"	"ENSG00000170142"	"UBE2E1"	"B2RBX4; C9J8K2; hsa:7324; K4DI90; P51965"	"Photodynamic therapy-induced unfolded protein response; 7q11.23 copy number variation syndrome"	"Assembly of the pre-replicative complex; Separation of Sister Chromatids; E3 ubiquitin ligases ubiquitinate target proteins; Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Antigen processing: Ubiquitination & Proteasome degradation; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; CDK-mediated phosphorylation and removal of Cdc6; ISG15 antiviral mechanism; Autodegradation of Cdh1 by Cdh1:APC/C; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of Cyclin B; Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase; Regulation of APC/C activators between G1/S and early anaphase; Phosphorylation of the APC/C; APC-Cdc20 mediated degradation of Nek2A; Senescence-Associated Secretory Phenotype (SASP); Transcriptional Regulation by VENTX; Aberrant regulation of mitotic exit in cancer due to RB1 defects"	"23"	"0"	"21.0"	"49.5"	"68.8"	"22.1"	"58.1"	"26.4"	"69.0"	"38.5"	"55.4"	"80.0"	"104.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P15170"	"Eukaryotic peptide chain release factor GTP-binding subunit ERF3A OS=Homo sapiens OX=9606 GN=GSPT1 PE=1 SV=1"	"3"	"1"	"2"	"1"	"499"	"55.7"	"5.62"	"379.11"	"3.03"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03143, Pf03144"	"2935"	"ENSG00000103342"	"GSPT1"	"hsa:2935; J3KQG6; P15170; Q96GF2"	""	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"4"	"0"	"28.1"	"111.6"	"108.4"	"24.7"	"88.9"	"32.6"	"118.2"	"88.4"	"124.1"	"228.7"	"434.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TCJ2"	"Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B OS=Homo sapiens OX=9606 GN=STT3B PE=1 SV=1"	"2"	"2"	"2"	"2"	"826"	"93.6"	"8.91"	"256.04"	"3.03"	"1"	"1"	"protein metabolism;other metabolic processes;stress response"	"other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf02516"	"201595"	"ENSG00000163527"	"STT3B"	"hsa:201595; Q8TCJ2; Q96JZ4; Q96KY7"	"N-glycan biosynthesis"	""	"1"	"0"	"197.8"	"424.7"	"405.4"	"175.1"	"390.9"	"209.8"	"292.7"	"238.1"	"352.0"	"499.9"	"774.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62995"	"Transformer-2 protein homolog beta OS=Homo sapiens OX=9606 GN=TRA2B PE=1 SV=1"	"3"	"1"	"1"	"1"	"288"	"33.6"	"11.25"	""	"3.03"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6434"	"ENSG00000136527"	"TRA2B"	"B4DVK2; D3DNU3; hsa:6434; O15449; P62995; Q15815; Q64283"	"mRNA processing"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle"	"5"	"0"	"19.3"	"66.2"	"44.0"	"21.1"	"54.7"	"20.3"	"60.3"	"59.1"	"75.0"	"83.8"	"137.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00165"	"HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2"	"4"	"1"	"2"	"1"	"279"	"31.6"	"4.92"	"362.90"	"3.02"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"other molecular function"	""	"10456"	"ENSG00000143575"	"HAX1"	"A8W4W9; A8W4X0; B4DUJ7; hsa:10456; O00165; Q5VYD5; Q5VYD7; Q96AU4; Q9BS80"	"Primary ovarian insufficiency"	""	"1"	"0"	"42.9"	"143.4"	"130.8"	"37.2"	"120.8"	"55.1"	"88.0"	"67.4"	"95.9"	"137.5"	"220.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35237"	"Serpin B6 OS=Homo sapiens OX=9606 GN=SERPINB6 PE=1 SV=3"	"4"	"1"	"2"	"1"	"376"	"42.6"	"5.27"	"364.38"	"3.01"	"1"	"1"	"stress response;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00079"	"5269"	"ENSG00000124570"	"SERPINB6"	"B2RBA8; hsa:5269; P35237; Q59F97; Q5TD06; Q7Z2Y7; Q96J44; Q9UDI7"	"Ectoderm differentiation"	"Neutrophil degranulation; Dissolution of Fibrin Clot"	"3"	"0"	"26.1"	"66.7"	"81.0"	"23.7"	"55.9"	"31.2"	"50.5"	"32.5"	"56.3"	"57.2"	"87.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P1F3"	"Costars family protein ABRACL OS=Homo sapiens OX=9606 GN=ABRACL PE=1 SV=1"	"16"	"1"	"2"	"1"	"81"	"9.1"	"6.29"	"323.05"	"3.01"	"1"	"1"	"other biological processes"	""	""	"Pf14705"	"58527"	"ENSG00000146386"	"ABRACL"	"hsa:58527; Q5SZC8; Q9P0A1; Q9P1F3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92530"	"Proteasome inhibitor PI31 subunit OS=Homo sapiens OX=9606 GN=PSMF1 PE=1 SV=2"	"8"	"1"	"1"	"1"	"271"	"29.8"	"5.74"	""	"3.00"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf08577, Pf11566"	"9491"	"ENSG00000125818"	"PSMF1"	"A0AVQ9; D3DVW3; hsa:9491; Q92530; Q9H4I1"	""	"Regulation of expression of SLITs and ROBOs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"59"	"0"	"18.9"	"51.1"	"46.8"	"13.3"	"41.8"	"19.4"	"24.7"	"19.8"	"29.0"	"38.1"	"88.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15054"	"DNA polymerase delta subunit 3 OS=Homo sapiens OX=9606 GN=POLD3 PE=1 SV=2"	"3"	"1"	"2"	"1"	"466"	"51.4"	"9.35"	"330.71"	"3.00"	"1"	"1"	"DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf09507"	"10714"	"ENSG00000077514"	"POLD3"	"B7ZAI6; hsa:10714; Q15054; Q32MZ9; Q32N00"	"Homologous recombination; Retinoblastoma gene in cancer; Pyrimidine metabolism; DNA replication; Base excision repair; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"HDR through Homologous Recombination (HRR); Termination of translesion DNA synthesis; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Polymerase switching on the C-strand of the telomere; Polymerase switching; Removal of the Flap Intermediate; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"26"	"0"	"26.9"	"44.4"	"43.2"	"20.6"	"51.2"	"21.8"	"45.1"	"39.8"	"65.5"	"66.5"	"74.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00483"	"Cytochrome c oxidase subunit NDUFA4 OS=Homo sapiens OX=9606 GN=NDUFA4 PE=1 SV=1"	"12"	"1"	"2"	"1"	"81"	"9.4"	"9.38"	"297.57"	"3.00"	"1"	"1"	"other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf06522"	"4697"	"ENSG00000189043"	"NDUFA4"	"A4D109; hsa:4697; O00483; Q6FHN5"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex IV assembly; Oxidative phosphorylation"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"7"	"0"	"42.7"	"125.3"	"116.3"	"36.1"	"117.7"	"52.1"	"82.5"	"62.9"	"79.8"	"118.6"	"165.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q04727"	"Transducin-like enhancer protein 4 OS=Homo sapiens OX=9606 GN=TLE4 PE=1 SV=3"	"1"	"1"	"2"	"1"	"773"	"83.7"	"7.50"	"404.66"	"3.00"	"1"	"1"	"cell-cell signaling;RNA metabolism OR transcription;signal transduction;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00400, Pf03920"	"7091"	"ENSG00000106829"	"TLE4"	"F8W6T6; hsa:7091; Q04727; Q3ZCS1; Q5T1Y2; Q6PCB3; Q9BZ07; Q9BZ08; Q9BZ09; Q9NSL3; Q9ULF9"	""	"Formation of the beta-catenin:TCF transactivating complex; Deactivation of the beta-catenin transactivating complex; NOTCH1 Intracellular Domain Regulates Transcription; Repression of WNT target genes"	"4"	"0"	"66.2"	"159.5"	"132.4"	"34.0"	"117.2"	"53.9"	"77.3"	"62.5"	"87.5"	"106.2"	"165.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30049"	"ATP synthase subunit delta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1D PE=1 SV=2"	"5"	"1"	"2"	"1"	"168"	"17.5"	"5.49"	"374.08"	"2.99"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity"	"Pf02823"	"513"	"ENSG00000099624"	"ATP5F1D"	"D6W5Y3; hsa:513; P30049; Q6FG90"	"Electron transport chain: OXPHOS system in mitochondria; 7q11.23 copy number variation syndrome; Oxidative phosphorylation"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"5"	"0"	"25.2"	"114.2"	"123.0"	"25.2"	"91.5"	"29.4"	"72.3"	"62.1"	"134.5"	"155.6"	"264.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14209"	"CD99 antigen OS=Homo sapiens OX=9606 GN=CD99 PE=1 SV=1"	"8"	"1"	"2"	"1"	"185"	"18.8"	"4.75"	"354.62"	"2.99"	"1"	"1"	"cell adhesion;other biological processes"	"plasma membrane;other membranes;other cell component"	""	"Pf12301"	"4267"	"ENSG00000002586"	"CD99"	"A6NIW1; hsa:4267; O00518; P14209; Q6ICV7"	""	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell; Cell surface interactions at the vascular wall"	"2"	"0"	"25.1"	"20.3"	"30.4"	"28.2"	"33.1"	"31.4"	"29.3"	"17.6"	"29.1"	"33.8"	"30.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5H9R7"	"Serine/threonine-protein phosphatase 6 regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PPP6R3 PE=1 SV=2"	"1"	"1"	"1"	"1"	"873"	"97.6"	"4.60"	""	"2.99"	""	"1"	"other biological processes"	"plasma membrane;other membranes;cytosol;nucleus"	"enzyme regulator activity;other molecular function"	"Pf04499"	"55291"	"ENSG00000110075"	"PPP6R3"	"hsa:55291; Q3B7I1; Q3I4Y0; Q3KR35; Q5H9R7; Q68CR3; Q7L4R8; Q8N3B2; Q96MB2; Q9H2K5; Q9H2K6; Q9HCL4; Q9NUY3"	""	"Telomere Extension By Telomerase; COPII-mediated vesicle transport"	"2"	"0"	"52.7"	"167.0"	"214.0"	"55.2"	"244.7"	"57.3"	"220.6"	"173.8"	"235.5"	"320.9"	"391.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13693"	"Translationally-controlled tumor protein OS=Homo sapiens OX=9606 GN=TPT1 PE=1 SV=1"	"9"	"1"	"2"	"1"	"172"	"19.6"	"4.93"	"346.92"	"2.99"	"1"	"1"	"transport;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00838"	"7178"	"ENSG00000133112"	"TPT1"	"B2R7E5; hsa:7178; P13693; Q6YLS2; Q7Z4J4; Q8TBK7; Q96EE2; Q9UC70"	""	""	"0"	"0"	"4.7"	"18.7"	"17.3"	"4.6"	"25.5"	"11.7"	"13.0"	"9.1"	"12.4"	"14.3"	"29.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96JP5"	"E3 ubiquitin-protein ligase ZFP91 OS=Homo sapiens OX=9606 GN=ZFP91 PE=1 SV=1"	"2"	"1"	"2"	"1"	"570"	"63.4"	"7.36"	"462.92"	"2.98"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"nucleus"	"other molecular function"	"Pf00096"	"80829"	"ENSG00000186660"	"ZFP91"	"A6NHC4; A8MSG7; hsa:80829; Q86V47; Q96JP4; Q96JP5; Q96QA3"	""	""	"0"	"0"	"7.7"	"35.9"	"27.0"	"4.8"	"16.8"	"10.6"	"24.1"	"20.1"	"20.4"	"28.5"	"36.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92905"	"COP9 signalosome complex subunit 5 OS=Homo sapiens OX=9606 GN=COPS5 PE=1 SV=4"	"2"	"1"	"2"	"1"	"334"	"37.6"	"6.54"	"260.79"	"2.98"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01398, Pf18323"	"10987"	"ENSG00000121022"	"COPS5"	"hsa:10987; O15386; Q6AW95; Q86WQ4; Q92905; Q9BQ17"	""	"Formation of TC-NER Pre-Incision Complex; Cargo recognition for clathrin-mediated endocytosis; Neddylation; DNA Damage Recognition in GG-NER"	"4"	"0"	"42.3"	"90.6"	"105.3"	"38.4"	"103.0"	"48.3"	"87.0"	"67.4"	"88.2"	"119.8"	"151.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96HU8"	"GTP-binding protein Di-Ras2 OS=Homo sapiens OX=9606 GN=DIRAS2 PE=1 SV=1"	"6"	"1"	"2"	"1"	"199"	"22.5"	"8.76"	"350.59"	"2.98"	"1"	"1"	"signal transduction"	"plasma membrane;other membranes"	"other molecular function"	"Pf00071"	"54769"	"ENSG00000165023"	"DIRAS2"	"B3KVM2; hsa:54769; Q96HU8"	""	""	"0"	"0"	"79.1"	"107.0"	"133.3"	"78.0"	"135.1"	"91.8"	"146.6"	"98.9"	"132.0"	"163.2"	"242.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13907"	"Isopentenyl-diphosphate Delta-isomerase 1 OS=Homo sapiens OX=9606 GN=IDI1 PE=1 SV=2"	"4"	"1"	"2"	"1"	"227"	"26.3"	"6.34"	"373.13"	"2.98"	"1"	"1"	"other metabolic processes"	"cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00293"	"3422"	"ENSG00000067064"	"IDI1"	"B4E155; hsa:3422; Q13907; Q32Q13; Q53GQ6; Q86U81; Q8WUX8; Q96IZ4; Q9BQ74"	"Target of rapamycin signaling; Cholesterol biosynthesis pathway; Sterol regulatory element-binding proteins (SREBP) signaling; Exercise-induced circadian regulation; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Cholesterol synthesis disorders; Cholesterol metabolism; Cholesterol biosynthesis pathway in hepatocytes; Enterocyte cholesterol metabolism"	"Activation of gene expression by SREBF (SREBP); Cholesterol biosynthesis"	"11"	"0"	"17.8"	"80.9"	"73.4"	"14.6"	"61.2"	"28.6"	"37.7"	"32.8"	"37.2"	"54.8"	"69.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBT2"	"SUMO-activating enzyme subunit 2 OS=Homo sapiens OX=9606 GN=UBA2 PE=1 SV=2"	"2"	"1"	"2"	"1"	"640"	"71.2"	"5.29"	"308.85"	"2.98"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00899, Pf14732, Pf16195"	"10054"	"ENSG00000126261"	"UBA2"	"B3KWB9; hsa:10054; O95605; Q59H87; Q6IBP6; Q9NTJ1; Q9UBT2; Q9UED2"	""	"SUMO is conjugated to E1 (UBA2:SAE1); SUMO is transferred from E1 to E2 (UBE2I, UBC9)"	"2"	"0"	"21.4"	"67.9"	"74.2"	"15.6"	"55.7"	"20.4"	"35.1"	"26.5"	"34.6"	"42.9"	"71.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13490"	"Baculoviral IAP repeat-containing protein 2 OS=Homo sapiens OX=9606 GN=BIRC2 PE=1 SV=2"	"1"	"1"	"2"	"1"	"618"	"69.9"	"6.70"	"331.82"	"2.97"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00619, Pf00653, Pf13920"	"329"	"ENSG00000110330"	"BIRC2"	"B4E026; hsa:329; Q13490; Q16516; Q4TTG0"	"TNF-related weak inducer of apoptosis (TWEAK) signaling pathway; TNF-alpha signaling pathway; Apoptosis; Glucocorticoid receptor pathway; Nuclear receptors meta-pathway; Focal adhesion; Photodynamic therapy-induced NF-kB survival signaling; Small cell lung cancer; Gastrin signaling pathway; Head and neck squamous cell carcinoma; 11p11.2 copy number variation syndrome"	"Ub-specific processing proteases; Regulation of TNFR1 signaling; TNFR1-induced NF-kappa-B signaling pathway; IKK complex recruitment mediated by RIP1; Regulation of necroptotic cell death; TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway; NOD1/2 Signaling Pathway; TICAM1, RIP1-mediated IKK complex recruitment; TNFR1-induced proapoptotic signaling; Apoptotic cleavage of cellular proteins"	"23"	"0"	"17.0"	"34.3"	"27.3"	"19.3"	"27.1"	"21.8"	"22.0"	"20.2"	"21.4"	"27.9"	"36.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P0M9"	"39S ribosomal protein L27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL27 PE=1 SV=1"	"7"	"1"	"2"	"1"	"148"	"16.1"	"10.42"	"381.11"	"2.97"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf01016"	"51264"	"ENSG00000108826"	"MRPL27"	"B2RE14; hsa:51264; Q9P0M9"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"29.2"	"56.7"	"70.8"	"27.2"	"57.4"	"31.8"	"51.8"	"44.2"	"63.4"	"90.3"	"162.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BUT1"	"3-hydroxybutyrate dehydrogenase type 2 OS=Homo sapiens OX=9606 GN=BDH2 PE=1 SV=2"	"3"	"1"	"2"	"1"	"245"	"26.7"	"7.65"	"308.46"	"2.97"	"1"	"1"	"other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf13561"	"56898"	"ENSG00000164039"	"BDH2"	"A8K295; B4DUF6; hsa:56898; Q503A0; Q6IA46; Q6UWD3; Q9BUT1; Q9H8S8; Q9NRX8"	""	"Synthesis of Ketone Bodies"	"1"	"0"	"81.8"	"273.1"	"516.7"	"88.8"	"214.6"	"116.1"	"238.1"	"207.2"	"251.6"	"349.1"	"534.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"B2RBV5"	"Putative MORF4 family-associated protein 1-like protein UPP OS=Homo sapiens OX=9606 PE=1 SV=1"	"9"	"1"	"2"	"1"	"119"	"13.4"	"8.22"	"336.46"	"2.96"	"1"	"1"	"other biological processes"	""	""	"Pf15155"	""	""	"MRFAP1L2"	"B2RBV5"	""	""	"0"	"0"	"4.2"	"10.2"	"13.3"	"2.5"	"9.1"	"5.4"	"15.5"	"15.4"	"18.9"	"34.7"	"58.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12756"	"Kinesin-like protein KIF1A OS=Homo sapiens OX=9606 GN=KIF1A PE=1 SV=2"	"1"	"1"	"2"	"1"	"1690"	"190.9"	"6.21"	"345.71"	"2.95"	"1"	"1"	"transport;other biological processes"	"other membranes;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00169, Pf00225, Pf00498, Pf12423, Pf12473, Pf16183"	"547"	"ENSG00000130294"	"KIF1A"	"B0I1S5; F5H045; hsa:547; O95068; Q12756; Q13355; Q14752; Q2NKJ6; Q4LE42; Q53T78; Q59GH1; Q63Z40; Q6P1R9; Q7KZ57"	"2q37 copy number variation syndrome"	"COPI-dependent Golgi-to-ER retrograde traffic; Kinesins"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49458"	"Signal recognition particle 9 kDa protein OS=Homo sapiens OX=9606 GN=SRP9 PE=1 SV=2"	"13"	"1"	"1"	"1"	"86"	"10.1"	"7.97"	""	"2.95"	""	"1"	"transport;other biological processes"	"other membranes;cytosol;ER/Golgi;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf05486"	"6726"	"ENSG00000143742"	"SRP9"	"A8K0N0; hsa:6726; P49458; Q6NVX0; Q8WTW0"	""	"SRP-dependent cotranslational protein targeting to membrane"	"1"	"0"	"15.3"	"36.2"	"33.0"	"14.2"	"28.9"	"15.3"	"32.8"	"37.4"	"72.2"	"151.3"	"407.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3D7"	"Mitochondrial import inner membrane translocase subunit TIM16 OS=Homo sapiens OX=9606 GN=PAM16 PE=1 SV=2"	"9"	"1"	"2"	"1"	"125"	"13.8"	"9.70"	"237.24"	"2.95"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion;other cell component"	""	"Pf03656"	"51025"	"ENSG00000217930; ENSG00000282228"	"PAM16"	"hsa:51025; Q6I9Z3; Q9H5X3; Q9Y3D7"	""	"Mitochondrial protein import"	"1"	"0"	"22.0"	"35.2"	"37.9"	"15.5"	"30.4"	"21.4"	"28.4"	"19.1"	"34.8"	"38.1"	"64.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WUH6"	"Transmembrane protein 263 OS=Homo sapiens OX=9606 GN=TMEM263 PE=1 SV=1"	"9"	"1"	"2"	"1"	"116"	"11.7"	"9.32"	"415.07"	"2.95"	"1"	"1"	""	"other membranes"	""	"Pf15475"	"90488"	"ENSG00000151135"	"TMEM263"	"B3KMN9; hsa:90488; Q8WUH6"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14019"	"Coactosin-like protein OS=Homo sapiens OX=9606 GN=COTL1 PE=1 SV=3"	"6"	"1"	"2"	"1"	"142"	"15.9"	"5.67"	"304.10"	"2.95"	"1"	"1"	"cell organization and biogenesis;stress response"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00241"	"23406"	"ENSG00000103187"	"COTL1"	"B2RDU3; D3DUL9; hsa:23406; Q14019; Q86XM5"	""	"Neutrophil degranulation"	"1"	"0"	"45.6"	"268.9"	"229.7"	"37.3"	"208.1"	"67.4"	"141.6"	"94.9"	"149.5"	"139.8"	"269.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82675"	"28S ribosomal protein S5, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS5 PE=1 SV=2"	"3"	"1"	"2"	"1"	"430"	"48.0"	"9.92"	"404.45"	"2.94"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00333, Pf03719"	"64969"	"ENSG00000144029"	"MRPS5"	"hsa:64969; P82675; Q4ZFY5; Q96LJ6; Q9BWI4; Q9BYC4"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"28.4"	"25.2"	"23.3"	"25.7"	"30.0"	"30.2"	"32.5"	"19.6"	"32.4"	"24.7"	"39.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96PU8"	"Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1"	"3"	"1"	"2"	"1"	"341"	"37.6"	"8.56"	"295.76"	"2.94"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf16544, Pf16551"	"9444"	"ENSG00000112531"	"QKI"	"hsa:9444; Q2I375; Q5MJQ1; Q969L9; Q96EJ3; Q96KA3; Q96PU6; Q96PU7; Q96PU8; Q9P0X6; Q9P0X7; Q9P0X8; Q9P0X9; Q9P0Y0; Q9P0Y1"	"VEGFA-VEGFR2 signaling; Exercise-induced circadian regulation"	"Signaling by BRAF and RAF1 fusions"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IUF8"	"Ribosomal oxygenase 2 OS=Homo sapiens OX=9606 GN=RIOX2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"465"	"52.8"	"6.70"	"353.60"	"2.94"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf08007, Pf20514"	"84864"	"ENSG00000170854"	"RIOX2"	"D3DN35; hsa:84864; Q6AHW4; Q6SKS0; Q8IU69; Q8IUF6; Q8IUF7; Q8IUF8; Q96C17; Q96KB0"	""	"HDMs demethylate histones"	"1"	"0"	"14.5"	"31.5"	"33.3"	"11.2"	"31.0"	"15.2"	"37.0"	"32.2"	"49.3"	"101.2"	"190.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6L8Q7"	"2',5'-phosphodiesterase 12 OS=Homo sapiens OX=9606 GN=PDE12 PE=1 SV=2"	"4"	"2"	"2"	"2"	"609"	"67.3"	"6.57"	"249.79"	"2.93"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf03372"	"201626"	"ENSG00000174840"	"PDE12"	"B4DTU8; hsa:201626; Q6L8Q7; Q8IYU3; Q8NDU2; Q8TE78"	"Phosphodiesterases in neuronal function"	"OAS antiviral response"	"2"	"0"	"90.9"	"79.3"	"102.1"	"72.5"	"115.7"	"104.0"	"105.0"	"67.7"	"120.7"	"158.2"	"277.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00151"	"PDZ and LIM domain protein 1 OS=Homo sapiens OX=9606 GN=PDLIM1 PE=1 SV=4"	"6"	"2"	"3"	"2"	"329"	"36.0"	"7.02"	"345.47"	"2.93"	"1"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;stress response;developmental processes;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412, Pf00595, Pf15936"	"9124"	"ENSG00000107438"	"PDLIM1"	"B2RBS6; hsa:9124; O00151; Q5VZH5; Q9BPZ9"	""	""	"0"	"0"	"57.2"	"227.0"	"190.3"	"29.5"	"176.8"	"57.0"	"75.3"	"51.6"	"72.7"	"84.5"	"169.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UPN9"	"E3 ubiquitin-protein ligase TRIM33 OS=Homo sapiens OX=9606 GN=TRIM33 PE=1 SV=3"	"1"	"1"	"1"	"1"	"1127"	"122.5"	"6.67"	""	"2.93"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00439, Pf00628, Pf00643, Pf13445"	"51592"	"ENSG00000197323"	"TRIM33"	"hsa:51592; O95855; Q5TG72; Q5TG73; Q5TG74; Q9C017; Q9UJ79; Q9UPN9"	"Ectoderm differentiation"	"Downregulation of SMAD2/3:SMAD4 transcriptional activity; Germ layer formation at gastrulation"	"3"	"0"	"9.7"	"18.2"	"22.8"	"7.5"	"14.5"	"11.0"	"16.1"	"15.3"	"14.7"	"24.0"	"29.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96IZ0"	"PRKC apoptosis WT1 regulator protein OS=Homo sapiens OX=9606 GN=PAWR PE=1 SV=1"	"4"	"1"	"2"	"1"	"340"	"36.5"	"5.41"	"439.87"	"2.93"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	""	"5074"	"ENSG00000177425"	"PAWR"	"hsa:5074; O75796; Q6FHY9; Q8N700; Q96IZ0"	""	""	"0"	"0"	"13.2"	"22.9"	"25.2"	"9.5"	"23.7"	"13.8"	"17.2"	"10.1"	"15.1"	"15.4"	"26.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q05823"	"2-5A-dependent ribonuclease OS=Homo sapiens OX=9606 GN=RNASEL PE=1 SV=2"	"2"	"1"	"2"	"1"	"741"	"83.5"	"6.65"	"317.40"	"2.92"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00023, Pf00069, Pf06479"	"6041"	"ENSG00000135828"	"RNASEL"	"hsa:6041; Q05823; Q5W0L2; Q6AI46"	""	"OAS antiviral response; Interferon alpha/beta signaling"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43765"	"Small glutamine-rich tetratricopeptide repeat-containing protein alpha OS=Homo sapiens OX=9606 GN=SGTA PE=1 SV=1"	"4"	"1"	"2"	"1"	"313"	"34.0"	"4.87"	"329.69"	"2.92"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00515, Pf13181, Pf16546"	"6449"	"ENSG00000104969"	"SGTA"	"D6W610; hsa:6449; O43765; Q6FIA9; Q9BTZ9"	""	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"	"1"	"0"	"4.6"	"67.1"	"52.9"	"0.2"	"40.9"	"12.3"	"9.9"	"8.1"	"14.7"	"17.7"	"34.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H8E8"	"Cysteine-rich protein 2-binding protein OS=Homo sapiens OX=9606 GN=KAT14 PE=1 SV=3"	"2"	"1"	"2"	"1"	"782"	"88.8"	"6.57"	"392.72"	"2.91"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf13673"	"57325"	"ENSG00000149474"	"KAT14"	"A2A2I5; hsa:57325; Q96GW6; Q96IH3; Q9H8E8; Q9HBF0; Q9UIY5"	""	"HATs acetylate histones; Formation of WDR5-containing histone-modifying complexes"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9UH03"	"Neuronal-specific septin-3 OS=Homo sapiens OX=9606 GN=SEPTIN3 PE=1 SV=3"	"4"	"1"	"2"	"1"	"358"	"40.7"	"7.20"	"352.93"	"2.91"	"1"	"1"	"cell cycle OR cell proliferation"	"cytoskeleton;other cell component"	"other molecular function"	"Pf00735"	"55964"	"ENSG00000100167"	"SEPTIN3"	"B1AHR0; hsa:55964; Q2NKJ7; Q59GF7; Q6IBZ6; Q8N3P3; Q9HD35; Q9UH03"	""	""	"0"	"0"	"9.8"	"16.8"	"17.0"	"8.5"	"18.1"	"8.9"	"17.5"	"18.1"	"30.8"	"39.8"	"62.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22307"	"Non-specific lipid-transfer protein OS=Homo sapiens OX=9606 GN=SCP2 PE=1 SV=2"	"2"	"1"	"2"	"1"	"547"	"59.0"	"6.89"	"288.53"	"2.91"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"cytosol;mitochondrion;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;transporter activity;other molecular function"	"Pf00108, Pf02036, Pf02803"	"6342"	"ENSG00000116171"	"SCP2"	"A6NM69; B4DGJ9; B4DHP6; C9JC79; D3DQ37; E1B6W5; F2Z3J1; hsa:6342; P22307; Q15432; Q16622; Q5VVZ1; Q6NXF4; Q99430"	"PPAR-alpha pathway; Nuclear receptors meta-pathway; Mitochondrial long chain fatty acid beta-oxidation; PPAR signaling pathway; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Mitochondrial fatty acid oxidation disorders; DNA damage response (only ATM dependent)"	"TYSND1 cleaves peroxisomal proteins; alpha-linolenic acid (ALA) metabolism"	"10"	"0"	"12.1"	"54.7"	"40.8"	"14.4"	"38.5"	"16.6"	"28.4"	"23.2"	"26.1"	"45.9"	"68.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75386"	"Tubby-related protein 3 OS=Homo sapiens OX=9606 GN=TULP3 PE=1 SV=2"	"8"	"2"	"2"	"2"	"442"	"49.6"	"7.74"	""	"2.91"	""	"2"	"developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01167, Pf16322"	"7289"	"ENSG00000078246"	"TULP3"	"B3KNB7; B7Z6A2; D3DUQ4; F8WBZ9; hsa:7289; O75386; Q8N5B0"	"H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity; Genes related to primary cilium development (based on CRISPR)"	"Hedgehog 'off' state"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q53ET0"	"CREB-regulated transcription coactivator 2 OS=Homo sapiens OX=9606 GN=CRTC2 PE=1 SV=2"	"2"	"1"	"2"	"1"	"693"	"73.3"	"7.11"	"304.31"	"2.91"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf12884, Pf12885, Pf12886"	"200186"	"ENSG00000160741"	"CRTC2"	"hsa:200186; Q53ET0; Q6UUV8; Q7Z3X7; Q8N332"	"AMP-activated protein kinase signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway"	"Circadian Clock; Heme signaling; Transcriptional activation of mitochondrial biogenesis"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6N069"	"N-alpha-acetyltransferase 16, NatA auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA16 PE=1 SV=2"	"1"	"1"	"1"	"1"	"864"	"101.4"	"7.87"	""	"2.90"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity"	"Pf07719, Pf12569"	"79612"	"ENSG00000172766"	"NAA16"	"B0QZ59; hsa:79612; Q5VSP9; Q6N069; Q6P2D5; Q8N5J3; Q8N870"	""	""	"0"	"0"	"0.0"	"3.1"	"3.5"	"0.0"	"2.8"	"0.0"	"11.7"	"7.0"	"24.9"	"34.5"	"95.0"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16134"	"Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial OS=Homo sapiens OX=9606 GN=ETFDH PE=1 SV=2"	"3"	"1"	"1"	"1"	"617"	"68.5"	"7.55"	""	"2.90"	""	"1"	"other metabolic processes;stress response"	"other membranes;mitochondrion"	"other molecular function"	"Pf01946, Pf05187"	"2110"	"ENSG00000171503"	"ETFDH"	"B4E3R9; hsa:2110; J3KND9; Q16134; Q7Z347"	"Riboflavin and CoQ disorders"	"Respiratory electron transport"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WVD3"	"E3 ubiquitin-protein ligase RNF138 OS=Homo sapiens OX=9606 GN=RNF138 PE=1 SV=1"	"4"	"1"	"2"	"1"	"245"	"28.2"	"6.93"	"341.11"	"2.89"	"1"	"1"	"cell-cell signaling;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05605, Pf13923, Pf18574"	"51444"	"ENSG00000134758"	"RNF138"	"B2RE17; hsa:51444; Q8WVD3; Q9H8K2; Q9UF87; Q9UKI6"	""	"Antigen processing: Ubiquitination & Proteasome degradation"	"1"	"0"	"35.3"	"60.5"	"63.1"	"31.8"	"60.5"	"28.0"	"77.0"	"153.8"	"371.4"	"536.1"	"573.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UI10"	"Translation initiation factor eIF-2B subunit delta OS=Homo sapiens OX=9606 GN=EIF2B4 PE=1 SV=2"	"2"	"1"	"2"	"1"	"523"	"57.5"	"9.38"	"381.99"	"2.89"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01008"	"8890"	"ENSG00000115211"	"EIF2B4"	"hsa:8890; Q53RY7; Q5BJF4; Q9BUV9; Q9UBG4; Q9UI10; Q9UIQ9; Q9UJ95"	"Translation factors; Primary ovarian insufficiency"	"Recycling of eIF2:GDP"	"3"	"0"	"6.8"	"45.0"	"33.1"	"8.1"	"22.8"	"11.6"	"10.4"	"9.8"	"13.4"	"19.2"	"40.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01484"	"Ankyrin-2 OS=Homo sapiens OX=9606 GN=ANK2 PE=1 SV=4"	"0"	"2"	"3"	"1"	"3957"	"433.4"	"5.14"	"665.35"	"2.89"	"2"	"1"	"cell-cell signaling;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00023, Pf00531, Pf00791, Pf12796, Pf17809"	"287"	"ENSG00000145362"	"ANK2"	"hsa:287; Q01484; Q01485; Q08AC7; Q08AC8; Q7Z3L5"	""	"COPI-mediated anterograde transport; Interaction between L1 and Ankyrins"	"2"	"0"	"14.0"	"23.0"	"18.6"	"6.6"	"13.1"	"8.6"	"41.0"	"34.7"	"63.8"	"72.8"	"92.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6Y288"	"Beta-1,3-glucosyltransferase OS=Homo sapiens OX=9606 GN=B3GLCT PE=1 SV=2"	"3"	"1"	"2"	"1"	"498"	"56.5"	"7.50"	"314.54"	"2.89"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf02434"	"145173"	"ENSG00000187676"	"B3GLCT"	"A8K5F8; hsa:145173; Q5W0H2; Q6NUI3; Q6Y288"	""	"Defective B3GALTL causes PpS; O-glycosylation of TSR domain-containing proteins"	"2"	"0"	"12.1"	"20.9"	"26.6"	"4.5"	"21.7"	"11.4"	"14.0"	"13.4"	"21.5"	"26.2"	"41.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TEM1"	"Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3"	"1"	"1"	"2"	"1"	"1887"	"205.0"	"6.81"	"343.75"	"2.89"	"1"	"1"	"transport"	"other membranes;ER/Golgi;nucleus"	""	"Pf02368"	"23225"	"ENSG00000132182"	"NUP210"	"A6NN56; hsa:23225; O94980; Q6NXG6; Q8NBJ1; Q8TEM1; Q9H6C8; Q9UFP3"	""	"ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; snRNP Assembly; Transport of Mature mRNA derived from an Intron-Containing Transcript; HCMV Late Events; HCMV Early Events; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"28"	"0"	"7.4"	"13.5"	"16.7"	"5.7"	"11.1"	"5.9"	"6.3"	"4.2"	"6.5"	"11.9"	"26.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96SB4"	"SRSF protein kinase 1 OS=Homo sapiens OX=9606 GN=SRPK1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"655"	"74.3"	"6.16"	"389.06"	"2.89"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"6732"	"ENSG00000096063"	"SRPK1"	"B4DS61; hsa:6732; Q12890; Q5R364; Q5R365; Q8IY12; Q96SB4"	"VEGFA-VEGFR2 signaling; mRNA processing"	"Maturation of nucleoprotein"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6YN16"	"Hydroxysteroid dehydrogenase-like protein 2 OS=Homo sapiens OX=9606 GN=HSDL2 PE=1 SV=1"	"4"	"1"	"2"	"1"	"418"	"45.4"	"7.99"	"316.34"	"2.88"	"1"	"1"	""	"mitochondrion;other cytoplasmic organelle"	"other molecular function"	"Pf00106, Pf02036"	"84263"	"ENSG00000119471"	"HSDL2"	"A8K1L4; A8K8X1; A8MSV3; hsa:84263; Q658M8; Q6YN16; Q9BT58"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16891"	"MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1"	"1"	"1"	"2"	"1"	"758"	"83.6"	"6.48"	"349.40"	"2.88"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"other membranes;mitochondrion"	""	"Pf09731"	"10989"	"ENSG00000132305"	"IMMT"	"B1H0U5; B2R5N6; hsa:10989; Q14539; Q15092; Q16891; Q68D41; Q69HW5; Q6IBL0; Q7Z3X1; Q8TAJ5; Q9P0V2"	""	"Cristae formation"	"1"	"0"	"18.9"	"53.5"	"46.6"	"17.2"	"54.2"	"20.9"	"38.0"	"32.5"	"45.1"	"46.5"	"85.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6NZY4"	"Zinc finger CCHC domain-containing protein 8 OS=Homo sapiens OX=9606 GN=ZCCHC8 PE=1 SV=2"	"3"	"1"	"2"	"1"	"707"	"78.5"	"4.87"	"399.48"	"2.88"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00098, Pf04046"	"55596"	"ENSG00000033030"	"ZCCHC8"	"hsa:55596; Q6NZY4; Q7L2P6; Q8N2K5; Q96SK7; Q9NSS2; Q9NSS3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7L804"	"Rab11 family-interacting protein 2 OS=Homo sapiens OX=9606 GN=RAB11FIP2 PE=1 SV=1"	"6"	"2"	"3"	"2"	"512"	"58.2"	"9.32"	"833.08"	"2.88"	"2"	"1"	"cell-cell signaling;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00168, Pf09457"	"22841"	"ENSG00000107560"	"RAB11FIP2"	"A6NEI4; hsa:22841; Q3I768; Q7L804; Q9Y2F0"	""	"Vasopressin regulates renal water homeostasis via Aquaporins"	"1"	"0"	"51.3"	"98.3"	"97.1"	"74.0"	"105.4"	"66.6"	"129.1"	"112.6"	"173.9"	"297.1"	"435.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WUY1"	"Protein THEM6 OS=Homo sapiens OX=9606 GN=THEM6 PE=1 SV=2"	"8"	"1"	"2"	"1"	"208"	"23.9"	"9.55"	"309.03"	"2.87"	"1"	"1"	""	"non-structural extracellular"	""	"Pf13279"	"51337"	"ENSG00000130193"	"THEM6"	"B2RDN6; hsa:51337; Q8NBN2; Q8WUY1; Q9NYI2"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBF8"	"Phosphatidylinositol 4-kinase beta OS=Homo sapiens OX=9606 GN=PI4KB PE=1 SV=1"	"1"	"1"	"2"	"1"	"816"	"91.3"	"6.25"	"311.45"	"2.87"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport;signal transduction"	"other membranes;cytosol;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf00454"	"5298"	"ENSG00000143393"	"PI4KB"	"B4DGI2; hsa:5298; O15096; P78405; Q5VWB9; Q5VWC0; Q5VWC1; Q9BWR6; Q9UBF8"	""	"Synthesis of PIPs at the Golgi membrane"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H4B0"	"Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OSGEPL1 PE=2 SV=2"	"4"	"2"	"3"	"2"	"414"	"45.1"	"8.56"	"555.34"	"2.87"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00814"	"64172"	"ENSG00000128694"	"OSGEPL1"	"hsa:64172; Q96EV9; Q96NH5; Q9H4B0"	""	""	"0"	"0"	"105.4"	"167.4"	"195.2"	"89.0"	"202.3"	"138.2"	"301.1"	"352.6"	"645.5"	"646.5"	"706.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9GZY8"	"Mitochondrial fission factor OS=Homo sapiens OX=9606 GN=MFF PE=1 SV=1"	"8"	"1"	"1"	"1"	"342"	"38.4"	"8.95"	""	"2.87"	""	"1"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"other membranes;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf05644"	"56947"	"ENSG00000168958"	"MFF"	"hsa:56947; Q567U1; Q658R6; Q9BVZ1; Q9GZY8; Q9H690; Q9NRG8"	"10q11.21q11.23 copy number variation syndrome"	""	"1"	"0"	"3.8"	"20.7"	"14.2"	"6.3"	"11.7"	"7.3"	"9.0"	"10.0"	"15.2"	"17.5"	"28.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5Q9"	"General transcription factor 3C polypeptide 3 OS=Homo sapiens OX=9606 GN=GTF3C3 PE=1 SV=1"	"3"	"2"	"3"	"2"	"886"	"101.2"	"5.07"	"684.53"	"2.87"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13181"	"9330"	"ENSG00000119041"	"GTF3C3"	"hsa:9330; Q4ZG48; Q86XJ8; Q8WX84; Q96B44; Q9H5I8; Q9NT97; Q9Y5Q9"	""	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter"	"3"	"0"	"49.6"	"93.6"	"98.6"	"44.2"	"118.4"	"55.2"	"100.0"	"69.8"	"100.9"	"90.5"	"127.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15904"	"V-type proton ATPase subunit S1 OS=Homo sapiens OX=9606 GN=ATP6AP1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"470"	"52.0"	"6.14"	"384.04"	"2.87"	"1"	"1"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"other membranes;ER/Golgi;other cytoplasmic organelle"	"other molecular function"	"Pf05827, Pf20520"	"537"	"ENSG00000071553"	"ATP6AP1"	"A6ZKI4; hsa:537; Q15904; Q8NBT4; Q9H0C7"	"Hepatitis B infection; Oxidative phosphorylation"	"RHOA GTPase cycle; Insulin receptor recycling; Transferrin endocytosis and recycling; Ion channel transport"	"6"	"0"	"7.0"	"35.1"	"28.4"	"6.9"	"26.7"	"11.3"	"12.5"	"7.9"	"14.8"	"20.8"	"31.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75688"	"Protein phosphatase 1B OS=Homo sapiens OX=9606 GN=PPM1B PE=1 SV=1"	"2"	"1"	"2"	"1"	"479"	"52.6"	"5.05"	"344.84"	"2.87"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;cytosol;nucleus"	"other molecular function"	"Pf00481, Pf07830"	"5495"	"ENSG00000138032"	"PPM1B"	"hsa:5495; O75688; Q461Q2; Q4J6C1; Q4J6C2; Q658R4; Q96ER6; Q9HAY8"	"MAPK signaling pathway"	"ISG15 antiviral mechanism; ALK mutants bind TKIs; Signaling by ALK fusions and activated point mutants"	"4"	"0"	"90.3"	"97.1"	"98.8"	"39.1"	"89.5"	"45.4"	"62.9"	"50.2"	"60.4"	"75.6"	"98.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z6E9"	"E3 ubiquitin-protein ligase RBBP6 OS=Homo sapiens OX=9606 GN=RBBP6 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1792"	"201.4"	"9.64"	"341.59"	"2.86"	"1"	"1"	"protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf04564, Pf08783, Pf13696"	"5930"	"ENSG00000122257"	"RBBP6"	"hsa:5930; Q147T5; Q15290; Q6DKH4; Q6P4C2; Q6YNC9; Q7Z6E8; Q7Z6E9; Q8N0V2; Q96PH3; Q9H3I8; Q9H5M5; Q9NPX4"	""	"RHOBTB1 GTPase cycle; Antigen processing: Ubiquitination & Proteasome degradation"	"2"	"0"	"3.3"	"11.6"	"11.2"	"3.9"	"11.0"	"6.0"	"12.0"	"10.2"	"22.8"	"26.2"	"27.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q06323"	"Proteasome activator complex subunit 1 OS=Homo sapiens OX=9606 GN=PSME1 PE=1 SV=1"	"5"	"1"	"2"	"1"	"249"	"28.7"	"6.02"	"345.56"	"2.86"	"1"	"1"	"other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf02251, Pf02252"	"5720"	"ENSG00000092010; ENSG00000284916"	"PSME1"	"A6NJG9; H0YNE3; hsa:5720; Q06323; Q6IBM2; Q9UEF4"	"Proteasome degradation"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"60"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96P47"	"Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 OS=Homo sapiens OX=9606 GN=AGAP3 PE=1 SV=2"	"1"	"1"	"2"	"1"	"875"	"95.0"	"7.97"	"264.74"	"2.85"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00071, Pf01412, Pf12796"	"116988"	"ENSG00000133612"	"AGAP3"	"B3KNZ8; E9PAL8; hsa:116988; Q59EN0; Q96P47; Q96RK3"	""	""	"0"	"0"	"48.3"	"94.3"	"84.7"	"43.9"	"111.9"	"63.5"	"141.1"	"233.5"	"371.7"	"547.7"	"727.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TBC4"	"NEDD8-activating enzyme E1 catalytic subunit OS=Homo sapiens OX=9606 GN=UBA3 PE=1 SV=2"	"2"	"1"	"2"	"1"	"463"	"51.8"	"5.45"	"307.11"	"2.85"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00899, Pf08825"	"9039"	"ENSG00000144744"	"UBA3"	"A6NLB5; A8K027; hsa:9039; O76088; Q8TBC4; Q9NTU3"	"Hijack of ubiquitination by SARS-CoV-2"	"Antigen processing: Ubiquitination & Proteasome degradation; Dectin-1 mediated noncanonical NF-kB signaling; NIK-->noncanonical NF-kB signaling; Neddylation"	"5"	"0"	"4.8"	"40.8"	"32.8"	"2.0"	"29.4"	"8.8"	"8.9"	"4.8"	"7.5"	"11.2"	"24.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13601"	"KRR1 small subunit processome component homolog OS=Homo sapiens OX=9606 GN=KRR1 PE=1 SV=4"	"2"	"1"	"2"	"1"	"381"	"43.6"	"9.77"	"313.21"	"2.85"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf17903"	"11103"	"ENSG00000111615"	"KRR1"	"A0FIK6; A0JLP0; B2R989; E7EUQ0; hsa:11103; Q13601; Q8NEA8; Q8TC37; Q96AT5"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"83.6"	"262.9"	"262.4"	"89.8"	"232.8"	"94.3"	"235.9"	"173.8"	"279.4"	"410.9"	"652.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q17R31"	"Putative deoxyribonuclease TATDN3 OS=Homo sapiens OX=9606 GN=TATDN3 PE=1 SV=1"	"7"	"1"	"2"	"1"	"274"	"30.3"	"7.15"	"274.44"	"2.85"	"1"	"1"	""	"nucleus"	"other molecular function"	"Pf01026"	"128387"	"ENSG00000203705"	"TATDN3"	"A6NGS3; B7Z1C1; B7Z978; B7ZLQ6; E9PJE5; E9PNH3; G3V151; hsa:128387; Q17R31; Q4G0L1"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NZZ3"	"Charged multivesicular body protein 5 OS=Homo sapiens OX=9606 GN=CHMP5 PE=1 SV=1"	"7"	"1"	"2"	"1"	"219"	"24.6"	"4.83"	"291.42"	"2.84"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	""	"Pf03357"	"51510"	"ENSG00000086065"	"CHMP5"	"B2RD95; B4DIR6; hsa:51510; Q5VXW2; Q96AV2; Q9HB68; Q9NYS4; Q9NZZ3; Q9Y323"	"Ferroptosis"	"Budding and maturation of HIV virion; Endosomal Sorting Complex Required For Transport (ESCRT)"	"3"	"0"	"53.9"	"59.4"	"61.5"	"32.9"	"80.3"	"47.1"	"78.2"	"61.5"	"60.8"	"93.1"	"109.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6IAA8"	"Ragulator complex protein LAMTOR1 OS=Homo sapiens OX=9606 GN=LAMTOR1 PE=1 SV=2"	"7"	"1"	"2"	"1"	"161"	"17.7"	"5.15"	"294.96"	"2.84"	"1"	"1"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;other cytoplasmic organelle"	"other molecular function"	"Pf15454"	"55004"	"ENSG00000149357"	"LAMTOR1"	"hsa:55004; Q6IAA8; Q8WZ09; Q9NWT0"	"Perturbations to host-cell autophagy, induced by SARS-CoV-2 proteins"	"Regulation of PTEN gene transcription; mTORC1-mediated signalling; Neutrophil degranulation; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RHOG GTPase cycle; Amino acids regulate mTORC1; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOJ GTPase cycle; TP53 Regulates Metabolic Genes; Macroautophagy; Energy dependent regulation of mTOR by LKB1-AMPK; RHOH GTPase cycle"	"17"	"0"	"23.4"	"39.0"	"42.9"	"20.9"	"45.2"	"26.6"	"40.3"	"34.8"	"35.6"	"65.7"	"55.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NX55"	"Huntingtin-interacting protein K OS=Homo sapiens OX=9606 GN=HYPK PE=1 SV=2"	"6"	"1"	"2"	"1"	"129"	"14.7"	"4.93"	"332.85"	"2.84"	"1"	"1"	"other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf04419, Pf19026"	"100137436; 101127706; 104002286; 104679625; 105491324; 105549422; 105588143; 108521295; 25764; 713266"	"ENSCATG00000038565; ENSGGOG00000014809; ENSMFAG00000057677; ENSMLEG00000000898; ENSMMUG00000022768; ENSMNEG00000018318; ENSPANG00000018102; ENSPPAG00000034659; ENSPTEG00000009792; ENSPTEG00000019135; ENSPTRG00000038721; ENSRBIG00000028237; ENSRROG00000039445; ENSTGEG00000007663"	"HYPK; LOC113219833"	"A0A024R5Q1; A0A1D5R5K3; A0A2I2YQJ1; A0A2J8NTT0; A0A2K5N035; A0A2K5TR12; A0A2K5XAQ0; A0A2K6AXP0; A0A2K6KBN5; A0A2K6QRU2; A0A2R9B6N1; A0A663DGD1; A0A6D2Y1W8; A0A8C9GZF6; A0A8D2ERJ4; A0A8J8XMG0; A9X1C4; F7GC11; G7MX15; G7PB77; H2Q9B3; hsa:25764; mcc:713266; mleu:105549422; mni:105491324; panu:100137436; ptr:104002286; rbb:108521295; rro:104679625"	""	""	"0"	"0"	"39.7"	"77.5"	"78.3"	"35.2"	"77.7"	"35.5"	"177.6"	"154.7"	"210.5"	"286.9"	"513.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NUQ8"	"ATP-binding cassette sub-family F member 3 OS=Homo sapiens OX=9606 GN=ABCF3 PE=1 SV=2"	"2"	"1"	"2"	"1"	"709"	"79.7"	"6.34"	"413.43"	"2.83"	"1"	"1"	"stress response"	""	"other molecular function"	"Pf00005, Pf12848"	"55324"	"ENSG00000161204"	"ABCF3"	"A8K241; hsa:55324; Q86UA2; Q8NAN1; Q96GS8; Q9H7A8; Q9NUQ8"	""	""	"0"	"0"	"4.4"	"22.9"	"14.9"	"6.1"	"12.3"	"5.8"	"11.4"	"8.6"	"13.5"	"20.0"	"25.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2U8"	"Inner nuclear membrane protein Man1 OS=Homo sapiens OX=9606 GN=LEMD3 PE=1 SV=2"	"1"	"1"	"2"	"1"	"911"	"99.9"	"7.55"	"413.32"	"2.83"	"1"	"1"	"other biological processes"	"other membranes;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03020, Pf09402"	"23592"	"ENSG00000174106"	"LEMD3"	"hsa:23592; Q9NT47; Q9NYA5; Q9Y2U8"	"Envelope proteins and their potential roles in EDMD physiopathology"	"RND3 GTPase cycle; RND2 GTPase cycle; RAC1 GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOD GTPase cycle; RND1 GTPase cycle; Initiation of Nuclear Envelope (NE) Reformation; Depolymerization of the Nuclear Lamina"	"12"	"0"	"14.8"	"58.2"	"58.5"	"19.4"	"49.7"	"18.3"	"37.8"	"40.4"	"77.7"	"126.2"	"205.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15428"	"Splicing factor 3A subunit 2 OS=Homo sapiens OX=9606 GN=SF3A2 PE=1 SV=2"	"2"	"1"	"2"	"1"	"464"	"49.2"	"9.64"	"358.16"	"2.82"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf12874, Pf16835"	"8175"	"ENSG00000104897"	"SF3A2"	"B2RBU1; D6W605; hsa:8175; O75245; Q15428"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"49.0"	"86.1"	"106.2"	"43.6"	"82.8"	"49.2"	"138.0"	"100.5"	"141.6"	"153.3"	"170.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09669"	"Cytochrome c oxidase subunit 6C OS=Homo sapiens OX=9606 GN=COX6C PE=1 SV=2"	"11"	"1"	"2"	"1"	"75"	"8.8"	"10.39"	"307.14"	"2.82"	"1"	"1"	"other metabolic processes"	"other membranes;mitochondrion"	""	"Pf02937"	"1345"	"ENSG00000164919"	"COX6C"	"B2R4D7; hsa:1345; P09669"	"Electron transport chain: OXPHOS system in mitochondria; Ciliary landscape; Nonalcoholic fatty liver disease; Mitochondrial complex IV assembly"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"7"	"0"	"115.1"	"486.5"	"415.1"	"73.8"	"328.6"	"129.3"	"173.0"	"157.0"	"226.1"	"277.1"	"558.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16629"	"Serine/arginine-rich splicing factor 7 OS=Homo sapiens OX=9606 GN=SRSF7 PE=1 SV=1"	"4"	"1"	"2"	"1"	"238"	"27.4"	"11.82"	"325.00"	"2.82"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6432"	"ENSG00000115875"	"SRSF7"	"B4DLU6; G5E9M3; hsa:6432; Q16629; Q564D3"	"mRNA processing"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"7"	"0"	"83.5"	"369.1"	"273.6"	"58.3"	"228.8"	"83.1"	"191.9"	"185.7"	"247.6"	"338.2"	"611.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P18754"	"Regulator of chromosome condensation OS=Homo sapiens OX=9606 GN=RCC1 PE=1 SV=1"	"4"	"2"	"3"	"2"	"421"	"44.9"	"7.52"	"621.29"	"2.81"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00415"	"1104"	"ENSG00000180198"	"RCC1"	"hsa:1104; P18754; Q16269; Q6NT97"	"22q11.2 copy number variation syndrome"	"Rev-mediated nuclear export of HIV RNA; Nuclear import of Rev protein; Postmitotic nuclear pore complex (NPC) reformation"	"4"	"0"	"33.2"	"130.4"	"120.8"	"24.6"	"93.1"	"35.3"	"102.9"	"88.1"	"129.8"	"197.1"	"337.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H6S0"	"3'-5' RNA helicase YTHDC2 OS=Homo sapiens OX=9606 GN=YTHDC2 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1430"	"160.1"	"8.40"	"273.21"	"2.81"	"1"	"1"	"cell cycle OR cell proliferation;other biological processes"	"ER/Golgi;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf01424, Pf04146, Pf04408, Pf07717"	"64848"	"ENSG00000047188"	"YTHDC2"	"B2RP66; hsa:64848; Q9H6S0"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96B26"	"Exosome complex component RRP43 OS=Homo sapiens OX=9606 GN=EXOSC8 PE=1 SV=1"	"4"	"1"	"2"	"1"	"276"	"30.0"	"5.30"	"270.71"	"2.81"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01138, Pf03725"	"11340"	"ENSG00000120699"	"EXOSC8"	"hsa:11340; O43480; Q5TBA5; Q96B26"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	"6"	"0"	"4.4"	"24.3"	"16.3"	"6.9"	"15.2"	"6.9"	"12.7"	"7.4"	"18.4"	"15.7"	"28.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5T5C0"	"Syntaxin-binding protein 5 OS=Homo sapiens OX=9606 GN=STXBP5 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1151"	"127.5"	"7.28"	"238.01"	"2.81"	"1"	"1"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00400, Pf08366, Pf08596"	"134957"	"ENSG00000164506"	"STXBP5"	"hsa:134957; Q14DF3; Q5T5C0; Q5T5C1; Q5T5C2; Q8NBG8; Q96NG9"	""	""	"0"	"0"	"3.4"	"5.7"	"4.1"	"2.1"	"6.1"	"6.0"	"3.4"	"4.1"	"21.1"	"24.8"	"55.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61011"	"Signal recognition particle 54 kDa protein OS=Homo sapiens OX=9606 GN=SRP54 PE=1 SV=1"	"2"	"1"	"2"	"1"	"504"	"55.7"	"8.75"	"310.77"	"2.80"	"1"	"1"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00448, Pf02881, Pf02978"	"6729"	"ENSG00000100883"	"SRP54"	"B2R759; B4DUW6; hsa:6729; P13624; P61011"	"VEGFA-VEGFR2 signaling; mRNA processing"	"SRP-dependent cotranslational protein targeting to membrane"	"3"	"0"	"13.4"	"37.7"	"40.2"	"11.4"	"33.5"	"16.7"	"33.9"	"31.1"	"48.6"	"59.4"	"91.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5VUJ6"	"Leucine-rich repeat and calponin homology domain-containing protein 2 OS=Homo sapiens OX=9606 GN=LRCH2 PE=1 SV=2"	"2"	"1"	"2"	"1"	"765"	"84.5"	"6.55"	"337.24"	"2.80"	"1"	"1"	""	""	""	"Pf00307, Pf13855"	"57631"	"ENSG00000130224"	"LRCH2"	"F5H2T1; hsa:57631; Q08AD5; Q5VUJ6; Q9HA88; Q9P233"	""	""	"0"	"0"	"11.4"	"32.7"	"32.6"	"13.7"	"32.2"	"18.6"	"36.9"	"29.6"	"44.1"	"68.6"	"84.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQ52"	"Zinc phosphodiesterase ELAC protein 2 OS=Homo sapiens OX=9606 GN=ELAC2 PE=1 SV=2"	"3"	"2"	"3"	"2"	"826"	"92.2"	"7.90"	"534.11"	"2.80"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf12706, Pf13691"	"60528"	"ENSG00000006744"	"ELAC2"	"B4DPL9; hsa:60528; Q6IA94; Q9BQ52; Q9HAS8; Q9HAS9; Q9NVT1"	""	"tRNA processing in the nucleus; tRNA processing in the mitochondrion; rRNA processing in the mitochondrion; tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis"	"4"	"0"	"47.6"	"205.1"	"172.9"	"46.7"	"170.7"	"68.5"	"76.4"	"68.0"	"118.6"	"214.8"	"423.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06850"	"Corticoliberin OS=Homo sapiens OX=9606 GN=CRH PE=1 SV=1"	"7"	"1"	"1"	"1"	"196"	"21.4"	"9.96"	""	"2.79"	""	"1"	"cell-cell signaling;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;other cell component"	"signal transduction activity or receptor binding"	"Pf00473"	"1392"	"ENSG00000147571"	"CRH"	"B3KQS4; hsa:1392; P06850"	"Corticotropin-releasing hormone signaling pathway; Myometrial relaxation and contraction pathways; Serotonin and anxiety-related events; Serotonin and anxiety; Orexin receptor pathway"	"G alpha (s) signalling events; Class B/2 (Secretin family receptors); MECP2 regulates transcription of neuronal ligands"	"8"	"0"	"111.5"	"72.5"	"88.5"	"73.8"	"94.4"	"83.3"	"101.9"	"63.8"	"94.9"	"108.1"	"141.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75312"	"Zinc finger protein ZPR1 OS=Homo sapiens OX=9606 GN=ZPR1 PE=1 SV=1"	"3"	"1"	"2"	"1"	"459"	"50.9"	"4.73"	"298.11"	"2.79"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf03367"	"8882"	"ENSG00000109917"	"ZPR1"	"hsa:8882; O75312; Q2TAA0"	""	""	"0"	"0"	"2.8"	"25.3"	"22.3"	"4.3"	"18.1"	"5.6"	"19.3"	"14.7"	"16.6"	"26.3"	"39.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99614"	"Tetratricopeptide repeat protein 1 OS=Homo sapiens OX=9606 GN=TTC1 PE=1 SV=1"	"11"	"2"	"3"	"2"	"292"	"33.5"	"4.84"	"835.42"	"2.79"	"2"	"1"	"other biological processes"	"cytosol"	"other molecular function"	"Pf00515, Pf13181"	"7265"	"ENSG00000113312"	"TTC1"	"B2RCT2; D3DQJ8; hsa:7265; Q99614; Q9BVT3"	""	""	"0"	"0"	"13.6"	"39.5"	"35.4"	"8.0"	"31.0"	"10.5"	"14.9"	"9.9"	"19.7"	"21.1"	"37.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62273"	"40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2"	"25"	"3"	"3"	"3"	"56"	"6.7"	"10.13"	"504.33"	"2.79"	"2"	"1"	"protein metabolism;other metabolic processes"	"other membranes;cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00253"	"6235"	"ENSG00000213741"	"RPS29"	"A8MZ73; hsa:6235; P30054; P62273"	"Cytoplasmic ribosomal proteins; 11p11.2 copy number variation syndrome"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"20"	"0"	"263.6"	"528.0"	"529.0"	"260.7"	"558.7"	"276.9"	"618.3"	"433.3"	"684.4"	"951.7"	"1622.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2Q5"	"Ragulator complex protein LAMTOR2 OS=Homo sapiens OX=9606 GN=LAMTOR2 PE=1 SV=1"	"14"	"1"	"1"	"1"	"125"	"13.5"	"5.40"	""	"2.78"	""	"1"	"signal transduction;other biological processes"	"plasma membrane;other membranes;other cytoplasmic organelle"	"enzyme regulator activity;other molecular function"	"Pf03259"	"28956"	"ENSG00000116586"	"LAMTOR2"	"hsa:28956; Q5VY97; Q5VY98; Q5VY99; Q9Y2Q5"	""	"Neutrophil degranulation; MAP2K and MAPK activation; Regulation of PTEN gene transcription; Amino acids regulate mTORC1; mTORC1-mediated signalling; TP53 Regulates Metabolic Genes; Macroautophagy; Energy dependent regulation of mTOR by LKB1-AMPK"	"9"	"0"	"11.5"	"20.7"	"20.5"	"9.1"	"22.8"	"11.4"	"19.5"	"11.8"	"18.9"	"26.8"	"39.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60502"	"Protein O-GlcNAcase OS=Homo sapiens OX=9606 GN=OGA PE=1 SV=2"	"1"	"1"	"2"	"1"	"916"	"102.8"	"4.91"	"273.21"	"2.78"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf07555"	"10724"	"ENSG00000198408"	"OGA"	"B7WPB9; D3DR79; E9PGF9; hsa:10724; O60502; O75166; Q86WV0; Q8IV98; Q9BVA5; Q9HAR0"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3Z3"	"Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 OS=Homo sapiens OX=9606 GN=SAMHD1 PE=1 SV=2"	"5"	"3"	"4"	"3"	"626"	"72.2"	"7.14"	"883.93"	"2.78"	"3"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01966, Pf07647"	"25939"	"ENSG00000101347"	"SAMHD1"	"B4E2A5; E1P5V2; hsa:25939; Q5JXG8; Q8N491; Q9H004; Q9H005; Q9H3U9; Q9Y3Z3"	""	"Interferon alpha/beta signaling; Nucleotide catabolism"	"2"	"0"	"6.8"	"25.7"	"26.2"	"5.5"	"22.7"	"9.0"	"8.8"	"8.9"	"12.9"	"19.4"	"40.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55039"	"Developmentally-regulated GTP-binding protein 2 OS=Homo sapiens OX=9606 GN=DRG2 PE=1 SV=1"	"3"	"1"	"2"	"1"	"364"	"40.7"	"8.88"	"238.53"	"2.77"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01926, Pf02824, Pf16897"	"1819"	"ENSG00000108591"	"DRG2"	"B2R8G5; hsa:1819; P55039; Q53Y50; Q9BWB2"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62306"	"Small nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=SNRPF PE=1 SV=1"	"15"	"1"	"2"	"1"	"86"	"9.7"	"4.67"	"390.61"	"2.77"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01423"	"6636"	"ENSG00000139343"	"SNRPF"	"A2VCR2; B2R498; hsa:6636; P62306; Q15356; Q6IBQ1; Q6P4I0"	"mRNA processing"	"snRNP Assembly; RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway; SARS-CoV-2 modulates host translation machinery; mRNA Splicing - Minor Pathway; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"8"	"0"	"10.8"	"14.1"	"18.9"	"11.4"	"16.9"	"11.4"	"22.2"	"16.7"	"20.9"	"27.8"	"30.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKX7"	"Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2"	"2"	"1"	"2"	"1"	"468"	"50.1"	"7.06"	"273.56"	"2.77"	"1"	"1"	"transport"	"other membranes;nucleus"	""	"Pf00638, Pf08911"	"10762"	"ENSG00000093000"	"NUP50"	"B1AHA4; B2RB15; hsa:10762; O75644; Q8N6V5; Q9NPM9; Q9NPR6; Q9P1K5; Q9UKX7"	""	"Rev-mediated nuclear export of HIV RNA; SUMOylation of DNA replication proteins; Regulation of HSF1-mediated heat shock response; ISG15 antiviral mechanism; HCMV Early Events; HCMV Late Events; Transcriptional regulation by small RNAs; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"28"	"0"	"7.0"	"17.4"	"28.7"	"8.9"	"21.1"	"11.4"	"11.5"	"8.2"	"16.1"	"17.1"	"28.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49757"	"Protein numb homolog OS=Homo sapiens OX=9606 GN=NUMB PE=1 SV=2"	"2"	"1"	"2"	"1"	"651"	"70.8"	"8.51"	"323.55"	"2.77"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00640, Pf06311"	"8650"	"ENSG00000133961"	"NUMB"	"B1P2N5; B1P2N6; B1P2N7; B1P2N8; B1P2N9; B4E2B1; hsa:8650; P49757; Q6NUQ7; Q86SY1; Q8WW73; Q9UBG1; Q9UEQ4; Q9UKE8; Q9UKE9; Q9UKF0; Q9UQJ4"	"Notch signaling; VEGFA-VEGFR2 signaling; Head and neck squamous cell carcinoma; Neurogenesis regulation in the olfactory epithelium; TROP2 regulatory signaling; Notch signaling pathway"	"Recycling pathway of L1; Degradation of GLI1 by the proteasome; Hedgehog 'on' state; Activated NOTCH1 Transmits Signal to the Nucleus"	"10"	"0"	"17.6"	"44.3"	"46.4"	"20.0"	"44.7"	"26.8"	"48.8"	"51.2"	"83.2"	"122.8"	"197.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43709"	"Probable 18S rRNA (guanine-N(7))-methyltransferase OS=Homo sapiens OX=9606 GN=BUD23 PE=1 SV=2"	"6"	"2"	"3"	"2"	"281"	"31.9"	"8.73"	"541.89"	"2.77"	"2"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf08241, Pf12589"	"114049"	"ENSG00000071462"	"BUD23"	"A8K501; C9K060; hsa:114049; O43709; Q96P12; Q9BQ58; Q9HBP9"	"7q11.23 copy number variation syndrome"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"3"	"0"	"103.6"	"157.3"	"151.2"	"81.5"	"134.2"	"83.1"	"251.0"	"244.0"	"302.1"	"429.5"	"473.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92556"	"Engulfment and cell motility protein 1 OS=Homo sapiens OX=9606 GN=ELMO1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"727"	"83.8"	"6.28"	"245.60"	"2.76"	"1"	"1"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf04727, Pf11841, Pf16457"	"9844"	"ENSG00000155849"	"ELMO1"	"A4D1X6; hsa:9844; Q29R79; Q6ZTJ0; Q92556; Q96PB0; Q9H0I1"	"Chemokine signaling pathway; CCL18 signaling pathway"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; VEGFA-VEGFR2 Pathway; PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases; Nef and signal transduction"	"7"	"0"	"5.1"	"19.3"	"20.3"	"7.3"	"15.8"	"9.3"	"7.9"	"15.0"	"15.4"	"20.9"	"39.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62312"	"U6 snRNA-associated Sm-like protein LSm6 OS=Homo sapiens OX=9606 GN=LSM6 PE=1 SV=1"	"13"	"1"	"2"	"1"	"80"	"9.1"	"9.58"	"331.56"	"2.76"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01423"	"11157"	"ENSG00000164167"	"LSM6"	"hsa:11157; P62312; Q4W5J5; Q9Y4Y8"	""	"mRNA Splicing - Major Pathway; mRNA decay by 5' to 3' exoribonuclease"	"2"	"0"	"53.4"	"152.5"	"136.1"	"31.2"	"120.4"	"46.4"	"74.6"	"55.1"	"94.4"	"90.4"	"183.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H1E5"	"Thioredoxin-related transmembrane protein 4 OS=Homo sapiens OX=9606 GN=TMX4 PE=1 SV=1"	"4"	"1"	"2"	"1"	"349"	"38.9"	"4.37"	"266.34"	"2.76"	"1"	"1"	""	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf00085"	"56255"	"ENSG00000125827"	"TMX4"	"hsa:56255; Q8N4P7; Q8NCC1; Q9H1E5; Q9UJA1; Q9ULQ8"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95292"	"Vesicle-associated membrane protein-associated protein B/C OS=Homo sapiens OX=9606 GN=VAPB PE=1 SV=3"	"3"	"1"	"2"	"1"	"243"	"27.2"	"7.30"	"335.17"	"2.76"	"1"	"1"	"cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00635"	"9217"	"ENSG00000124164"	"VAPB"	"A2A2F2; hsa:9217; O95292; O95293; Q9P0H0"	"Ciliary landscape"	"RHOC GTPase cycle; RHOA GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RHOD GTPase cycle; Sphingolipid de novo biosynthesis"	"7"	"0"	"69.3"	"279.2"	"236.8"	"50.9"	"202.6"	"77.0"	"123.3"	"113.0"	"149.1"	"215.5"	"455.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13155"	"Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 OS=Homo sapiens OX=9606 GN=AIMP2 PE=1 SV=2"	"4"	"1"	"2"	"1"	"320"	"35.3"	"8.22"	"323.49"	"2.76"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf14497, Pf16780, Pf18569"	"7965"	"ENSG00000106305"	"AIMP2"	"F8W950; hsa:7965; Q13155; Q75MR1; Q96CZ5; Q9P1L2"	"Osteoclast signaling; Transcriptional activation by NRF2 in response to phytochemicals; NRF2-ARE regulation"	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UGN5"	"Poly [ADP-ribose] polymerase 2 OS=Homo sapiens OX=9606 GN=PARP2 PE=1 SV=2"	"1"	"1"	"2"	"1"	"583"	"66.2"	"8.88"	"336.49"	"2.75"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00644, Pf02877, Pf05406"	"10038"	"ENSG00000129484"	"PARP2"	"hsa:10038; Q8TEU4; Q9NUV2; Q9UGN5; Q9UMR4; Q9Y6C8"	"NAD+ biosynthetic pathways; Base excision repair; Peroxiredoxin 2 induced ovarian failure; DNA repair pathways, full network; 10q11.21q11.23 copy number variation syndrome"	"Dual Incision in GG-NER; Formation of Incision Complex in GG-NER; DNA Damage Recognition in GG-NER; HDR through MMEJ (alt-NHEJ); POLB-Dependent Long Patch Base Excision Repair"	"10"	"0"	"45.5"	"82.2"	"85.5"	"40.7"	"88.0"	"46.6"	"106.7"	"87.7"	"406.8"	"652.9"	"880.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3B4"	"Splicing factor 3B subunit 6 OS=Homo sapiens OX=9606 GN=SF3B6 PE=1 SV=1"	"10"	"1"	"1"	"1"	"125"	"14.6"	"9.38"	""	"2.75"	""	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076"	"51639"	"ENSG00000115128"	"SF3B6"	"hsa:51639; Q53TM1; Q9Y3B4"	""	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"2"	"0"	"6.8"	"32.6"	"25.8"	"10.0"	"30.1"	"10.2"	"23.6"	"21.9"	"29.6"	"41.2"	"78.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BUL8"	"Programmed cell death protein 10 OS=Homo sapiens OX=9606 GN=PDCD10 PE=1 SV=1"	"5"	"1"	"2"	"1"	"212"	"24.7"	"8.19"	"301.77"	"2.75"	"1"	"1"	"cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf06840"	"11235"	"ENSG00000114209"	"PDCD10"	"A8K515; D3DNN5; hsa:11235; O14811; Q9BUL8"	""	""	"0"	"0"	"61.1"	"242.6"	"194.5"	"44.6"	"176.4"	"55.7"	"133.2"	"124.3"	"161.7"	"240.1"	"394.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15102"	"Platelet-activating factor acetylhydrolase IB subunit gamma OS=Homo sapiens OX=9606 GN=PAFAH1B3 PE=1 SV=1"	"4"	"1"	"2"	"1"	"231"	"25.7"	"6.84"	"293.54"	"2.74"	"1"	"1"	"other metabolic processes;developmental processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf13472"	"5050"	"ENSG00000079462"	"PAFAH1B3"	"hsa:5050; Q15102; Q53X88"	""	"COPI-independent Golgi-to-ER retrograde traffic"	"1"	"0"	"18.2"	"159.5"	"133.9"	"10.8"	"101.6"	"26.9"	"55.2"	"37.7"	"55.6"	"80.3"	"137.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75915"	"PRA1 family protein 3 OS=Homo sapiens OX=9606 GN=ARL6IP5 PE=1 SV=1"	"11"	"1"	"2"	"1"	"188"	"21.6"	"9.77"	"352.84"	"2.74"	"1"	"1"	"other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi"	""	"Pf03208"	"10550"	"ENSG00000144746"	"ARL6IP5"	"B2R6V5; hsa:10550; O75915; Q53ES3; Q5KU08"	""	"Glutamate Neurotransmitter Release Cycle"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30048"	"Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3"	"5"	"1"	"2"	"1"	"256"	"27.7"	"7.78"	"270.73"	"2.73"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00578, Pf10417"	"10935"	"ENSG00000165672"	"PRDX3"	"B2R7Z0; D3DRC9; E9PH29; hsa:10935; P30048; P35690; Q0D2H1; Q13776; Q5T5V2; Q96HK4"	"Selenium micronutrient network"	"Detoxification of Reactive Oxygen Species"	"2"	"0"	"6.6"	"94.6"	"63.2"	"1.6"	"32.5"	"11.4"	"20.9"	"14.4"	"19.2"	"28.4"	"67.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95861"	"3'(2'),5'-bisphosphate nucleotidase 1 OS=Homo sapiens OX=9606 GN=BPNT1 PE=1 SV=1"	"7"	"1"	"1"	"1"	"308"	"33.4"	"5.69"	""	"2.73"	""	"1"	"other metabolic processes;developmental processes"	"cytosol"	"other molecular function"	"Pf00459"	"10380"	"ENSG00000162813"	"BPNT1"	"A8K7C8; B4DPS5; B4DUS9; D3DTA9; hsa:10380; O95861; Q8WVL5; Q9UGJ3"	""	"Cytosolic sulfonation of small molecules"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P28331"	"NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS1 PE=1 SV=3"	"1"	"1"	"2"	"1"	"727"	"79.4"	"6.23"	"283.50"	"2.73"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00384, Pf09326, Pf10588, Pf13510"	"4719"	"ENSG00000023228; ENSG00000283447"	"NDUFS1"	"B4DIN9; B4DJA0; B4DPG1; B4DUC1; E7ENF3; hsa:4719; P28331; Q53TR8; Q8N1C4; Q8TCC9"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"35.7"	"110.4"	"106.6"	"38.1"	"78.8"	"28.8"	"65.5"	"50.5"	"75.6"	"123.3"	"201.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NVC6"	"Mediator of RNA polymerase II transcription subunit 17 OS=Homo sapiens OX=9606 GN=MED17 PE=1 SV=2"	"2"	"1"	"2"	"1"	"651"	"72.8"	"7.44"	"256.34"	"2.73"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf10156"	"9440"	"ENSG00000042429"	"MED17"	"B3KN07; hsa:9440; Q9HA81; Q9NVC6; Q9UNP7; Q9Y2W0; Q9Y660"	""	"PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; Generic Transcription Pathway"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EY8"	"Corrinoid adenosyltransferase OS=Homo sapiens OX=9606 GN=MMAB PE=1 SV=1"	"4"	"1"	"2"	"1"	"250"	"27.4"	"8.60"	"356.26"	"2.72"	"1"	"1"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf01923"	"326625"	"ENSG00000139428"	"MMAB"	"C5HU05; hsa:326625; Q96EY8; Q9BSH0"	"Vitamin B12 metabolism"	"Cobalamin (Cbl) metabolism; Defective MMAB causes MMA, cblB type"	"3"	"0"	"46.1"	"158.6"	"145.1"	"38.9"	"116.9"	"57.4"	"92.8"	"82.1"	"109.3"	"145.8"	"225.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P41227"	"N-alpha-acetyltransferase 10 OS=Homo sapiens OX=9606 GN=NAA10 PE=1 SV=1"	"6"	"1"	"2"	"1"	"235"	"26.4"	"5.64"	"409.81"	"2.72"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00583"	"8260"	"ENSG00000102030"	"NAA10"	"A6NM98; hsa:8260; P41227"	""	""	"0"	"0"	"7.5"	"8.8"	"12.4"	"2.5"	"14.9"	"5.3"	"49.1"	"32.6"	"40.9"	"58.6"	"94.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15349"	"Ribosomal protein S6 kinase alpha-2 OS=Homo sapiens OX=9606 GN=RPS6KA2 PE=1 SV=2"	"4"	"2"	"3"	"2"	"733"	"83.2"	"8.68"	"338.27"	"2.72"	"1"	"2"	"cell-cell signaling;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00433"	"6196"	"ENSG00000071242"	"RPS6KA2"	"B3KTK9; hsa:6196; Q15349; Q15419; Q59GJ3; Q5TI68; Q96J38; Q9UJN5"	"Prolactin signaling pathway; Angiopoietin-like protein 8 regulatory pathway; Thermogenesis; EGF/EGFR signaling pathway; Translation inhibitors in chronically activated PDGFRA cells; Cytoplasmic ribosomal proteins; Insulin signaling; Host-pathogen interaction of human coronaviruses - MAPK signaling"	"Senescence-Associated Secretory Phenotype (SASP); Recycling pathway of L1; RSK activation; ERK/MAPK targets; CREB phosphorylation; Gastrin-CREB signalling pathway via PKC and MAPK"	"15"	"0"	"58.2"	"98.2"	"107.4"	"46.1"	"101.5"	"73.5"	"102.8"	"59.7"	"107.7"	"136.6"	"183.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96CS3"	"FAS-associated factor 2 OS=Homo sapiens OX=9606 GN=FAF2 PE=1 SV=2"	"4"	"2"	"3"	"2"	"445"	"52.6"	"5.62"	"525.84"	"2.71"	"2"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport"	"non-structural extracellular;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00789, Pf14555"	"23197"	"ENSG00000113194"	"FAF2"	"hsa:23197; O94963; Q8IUF2; Q96CS3; Q9BRP2; Q9BVM7"	""	"Neutrophil degranulation; RHOA GTPase cycle"	"2"	"0"	"49.5"	"179.8"	"154.2"	"47.2"	"142.6"	"75.8"	"84.3"	"61.3"	"93.1"	"134.3"	"215.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92614"	"Unconventional myosin-XVIIIa OS=Homo sapiens OX=9606 GN=MYO18A PE=1 SV=3"	"1"	"1"	"2"	"1"	"2054"	"233.0"	"6.30"	"473.73"	"2.71"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00063, Pf01576, Pf17820"	"399687"	"ENSG00000196535"	"MYO18A"	"hsa:399687; Q5H9U3; Q5QD01; Q5W9F9; Q5W9G1; Q8IXP8; Q92614"	""	"Signaling by cytosolic FGFR1 fusion mutants; Signaling by FGFR1 in disease; Signaling by FLT3 fusion proteins"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96NB3"	"Zinc finger protein 830 OS=Homo sapiens OX=9606 GN=ZNF830 PE=1 SV=2"	"5"	"1"	"1"	"1"	"372"	"42.0"	"5.31"	""	"2.71"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf12874"	"91603"	"ENSG00000198783"	"ZNF830"	"hsa:91603; Q96F60; Q96GZ5; Q96NB3; Q9BU38"	"17q12 copy number variation syndrome"	"mRNA Splicing - Major Pathway; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of TC-NER Pre-Incision Complex"	"6"	"0"	"10.5"	"23.5"	"24.6"	"12.5"	"29.9"	"11.4"	"22.3"	"15.4"	"35.1"	"35.3"	"51.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49642"	"DNA primase small subunit OS=Homo sapiens OX=9606 GN=PRIM1 PE=1 SV=1"	"4"	"2"	"3"	"2"	"420"	"49.9"	"8.21"	"559.54"	"2.71"	"2"	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf01896"	"5557"	"ENSG00000198056"	"PRIM1"	"hsa:5557; P49642"	"Retinoblastoma gene in cancer; Pyrimidine metabolism; G1 to S cell cycle control; DNA replication"	"Polymerase switching on the C-strand of the telomere; Polymerase switching; Removal of the Flap Intermediate; Activation of the pre-replicative complex; Defective pyroptosis; Inhibition of replication initiation of damaged DNA by RB1/E2F1; Telomere C-strand synthesis initiation; DNA replication initiation"	"13"	"0"	"83.5"	"147.5"	"154.1"	"65.6"	"170.3"	"97.3"	"139.1"	"87.9"	"159.0"	"162.6"	"230.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NR56"	"Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"388"	"41.8"	"8.90"	"281.57"	"2.70"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00642, Pf14608"	"4154"	"ENSG00000152601"	"MBNL1"	"E9PBW7; hsa:4154; O43311; O43797; Q86UV8; Q86UV9; Q96P92; Q96RE3; Q9NR56"	"Adipogenesis"	""	"1"	"0"	"26.3"	"54.8"	"57.5"	"29.8"	"47.5"	"27.8"	"66.1"	"48.4"	"58.4"	"93.9"	"122.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O96013"	"Serine/threonine-protein kinase PAK 4 OS=Homo sapiens OX=9606 GN=PAK4 PE=1 SV=1"	"2"	"1"	"2"	"1"	"591"	"64.0"	"9.73"	"254.73"	"2.70"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;ER/Golgi;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00786"	"10298"	"ENSG00000130669"	"PAK4"	"B4DGG6; hsa:10298; O96013; Q8N4E1; Q8NCH5; Q8NDE3; Q9BU33; Q9ULS8"	"Integrin-mediated cell adhesion; Focal adhesion; Ras signaling; Pancreatic adenocarcinoma pathway; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-Merlin signaling dysregulation; Neural crest cell migration during development; Neural crest cell migration in cancer; 22q11.2 copy number variation syndrome; Pleural mesothelioma; Regulation of actin cytoskeleton; TROP2 regulatory signaling; ErbB signaling pathway"	"RHOG GTPase cycle; RAC2 GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RAC3 GTPase cycle; RHOJ GTPase cycle; RHOV GTPase cycle; RHOU GTPase cycle; Activation of RAC1; RHOH GTPase cycle"	"24"	"0"	"20.8"	"56.4"	"57.2"	"24.4"	"60.5"	"33.7"	"72.1"	"61.0"	"73.5"	"116.6"	"118.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BVS5"	"tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=TRMT61B PE=1 SV=2"	"3"	"1"	"2"	"1"	"477"	"52.9"	"6.62"	"321.45"	"2.70"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf08704"	"55006"	"ENSG00000171103"	"TRMT61B"	"hsa:55006; Q9BVS5; Q9H0Q9; Q9NWS7"	""	"tRNA modification in the mitochondrion"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6ZV50"	"DNA-binding protein RFX8 OS=Homo sapiens OX=9606 GN=RFX8 PE=2 SV=2"	"2"	"1"	"1"	"1"	"586"	"66.2"	"6.09"	""	"2.70"	""	"1"	"RNA metabolism OR transcription;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02257"	"731220"	"ENSG00000196460"	"RFX8"	"B4DQ32; hsa:731220; Q6ZV50"	""	""	"0"	"0"	"77.4"	"54.9"	"83.5"	"57.7"	"100.7"	"74.1"	"361.5"	"221.7"	"358.4"	"311.2"	"458.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HBK9"	"Arsenite methyltransferase OS=Homo sapiens OX=9606 GN=AS3MT PE=1 SV=3"	"3"	"1"	"2"	"1"	"375"	"41.7"	"6.20"	"265.32"	"2.70"	"1"	"1"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf13847"	"57412"	"ENSG00000214435"	"AS3MT"	"A6NP79; hsa:57412; Q0VDK3; Q0VDK4; Q5PZ02; Q9HBK9"	"Arsenic metabolism and reactive oxygen species generation"	"Methylation"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H6K5"	"Proline-rich protein 36 OS=Homo sapiens OX=9606 GN=PRR36 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1346"	"132.7"	"10.48"	"322.16"	"2.69"	"1"	"1"	""	""	""	"Pf15363"	"80164"	"ENSG00000183248"	"PRR36"	"A0A087WZ52; hsa:80164; Q9H3X1; Q9H6K5"	""	""	"0"	"0"	"11.0"	"23.9"	"19.2"	"9.2"	"17.7"	"6.9"	"63.4"	"58.0"	"61.6"	"62.3"	"88.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WX93"	"Palladin OS=Homo sapiens OX=9606 GN=PALLD PE=1 SV=3"	"1"	"1"	"2"	"1"	"1383"	"150.5"	"7.09"	"288.71"	"2.69"	"1"	"1"	"cell adhesion;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf07679"	"23022"	"ENSG00000129116"	"PALLD"	"B3KTG2; B5MD56; B7ZMM5; hsa:23022; Q7L3E0; Q7Z3W0; Q86WE8; Q8N1M2; Q8WX93; Q9UGA0; Q9UQF5; Q9Y2J6; Q9Y3E9"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6ZSZ5"	"Rho guanine nucleotide exchange factor 18 OS=Homo sapiens OX=9606 GN=ARHGEF18 PE=1 SV=4"	"2"	"1"	"1"	"1"	"1361"	"151.5"	"6.33"	""	"2.69"	""	"1"	"cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00621, Pf17838"	"23370"	"ENSG00000104880"	"ARHGEF18"	"A8MV62; B5ME81; hsa:23370; I3L1I5; O60274; Q6DD92; Q6ZSZ5"	""	"G alpha (12/13) signalling events; RHOA GTPase cycle; RAC1 GTPase cycle; NRAGE signals death through JNK; TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94842"	"TOX high mobility group box family member 4 OS=Homo sapiens OX=9606 GN=TOX4 PE=1 SV=1"	"2"	"1"	"2"	"1"	"621"	"66.2"	"5.06"	"288.30"	"2.68"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00505"	"9878"	"ENSG00000092203"	"TOX4"	"B4DPY8; B4DSM0; E7EV69; hsa:9878; O94842"	""	""	"0"	"0"	"14.1"	"25.3"	"27.6"	"13.8"	"23.9"	"13.4"	"27.1"	"15.9"	"21.6"	"30.4"	"44.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96PV7"	"Protein FAM193B OS=Homo sapiens OX=9606 GN=FAM193B PE=1 SV=3"	"1"	"1"	"2"	"1"	"902"	"96.5"	"7.90"	"248.83"	"2.68"	"1"	"1"	""	"nucleus;other cell component"	""	"Pf15914"	"54540"	"ENSG00000146067"	"FAM193B"	"E9PET5; Q96PV7; Q9NW00"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12802"	"A-kinase anchor protein 13 OS=Homo sapiens OX=9606 GN=AKAP13 PE=1 SV=2"	"0"	"1"	"2"	"1"	"2813"	"307.4"	"5.24"	"327.11"	"2.67"	"1"	"1"	"transport;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf00621, Pf10522"	"11214"	"ENSG00000170776"	"AKAP13"	"hsa:11214; Q12802; Q14572; Q59FP6; Q86W90; Q8WXQ6; Q96JP6; Q96P79; Q9Y5T0; Q9Y5T6"	"Glucocorticoid receptor pathway; Nuclear receptors meta-pathway; G protein signaling pathways"	"RHOC GTPase cycle; RHOA GTPase cycle; NRAGE signals death through JNK; G alpha (12/13) signalling events; RHOB GTPase cycle"	"8"	"0"	"17.4"	"20.9"	"32.4"	"15.0"	"24.1"	"17.0"	"49.7"	"38.2"	"46.1"	"60.0"	"70.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46937"	"Transcriptional coactivator YAP1 OS=Homo sapiens OX=9606 GN=YAP1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"504"	"54.4"	"5.17"	"319.57"	"2.67"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;stress response;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00397"	"10413"	"ENSG00000137693"	"YAP1"	"B4DTY1; B7ZA01; E3WEB5; E3WEB6; E9PRV2; F5H202; hsa:10413; K0KQ18; K0KYZ8; K0L195; K0L1G3; P46937; Q7Z574; Q8IUY9"	"Mesodermal commitment pathway; Mesodermal commitment pathway; RAC1/PAK1/p38/MMP2 pathway; miR-509-3p alteration of YAP1/ECM axis; Ciliary landscape; Leukocyte-intrinsic Hippo pathway functions; Netrin-UNC5B signaling pathway; Galanin receptor pathway; Pleural mesothelioma"	"RUNX2 regulates osteoblast differentiation; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Formation of axial mesoderm; Nuclear signaling by ERBB4; Signaling by Hippo; YAP1- and WWTR1 (TAZ)-stimulated gene expression; EGR2 and SOX10-mediated initiation of Schwann cell myelination; RUNX3 regulates YAP1-mediated transcription"	"17"	"0"	"113.7"	"138.4"	"152.1"	"81.5"	"135.9"	"109.4"	"134.1"	"94.6"	"135.9"	"157.2"	"203.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKA9"	"Polypyrimidine tract-binding protein 2 OS=Homo sapiens OX=9606 GN=PTBP2 PE=1 SV=1"	"5"	"2"	"5"	"1"	"531"	"57.5"	"8.66"	"1406.24"	"2.67"	"2"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf11835, Pf13893"	"58155"	"ENSG00000117569"	"PTBP2"	"hsa:58155; Q8N0Z1; Q8N160; Q8NFB0; Q8NFB1; Q969N9; Q96Q76; Q9UKA9"	"Genes targeted by miRNAs in adipocytes; mRNA processing"	""	"2"	"0"	"2.9"	"15.2"	"10.3"	"3.0"	"11.3"	"7.5"	"14.4"	"7.8"	"10.6"	"17.2"	"24.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15198"	"Mothers against decapentaplegic homolog 9 OS=Homo sapiens OX=9606 GN=SMAD9 PE=1 SV=1"	"3"	"1"	"2"	"1"	"467"	"52.5"	"7.77"	"408.69"	"2.67"	"1"	"1"	"RNA metabolism OR transcription;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03165, Pf03166"	"4093"	"ENSG00000120693"	"SMAD9"	"A2A2Y6; hsa:4093; O14989; O15198; Q5TBA1"	"Differentiation of white and brown adipocyte; BMP2-WNT4-FOXO1 pathway in primary endometrial stromal cell differentiation; Embryonic stem cell pluripotency pathways; Neovascularisation processes; Osteoblast differentiation and related diseases; TGF-beta receptor signaling in skeletal dysplasias; Clock-controlled autophagy in bone metabolism; A network map of Macrophage-stimulating protein (MSP) signaling; TGF-beta receptor signaling"	"Signaling by BMP"	"10"	"0"	"17.4"	"29.8"	"36.5"	"15.2"	"30.6"	"17.9"	"36.6"	"43.1"	"109.1"	"171.5"	"224.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46108"	"Adapter molecule crk OS=Homo sapiens OX=9606 GN=CRK PE=1 SV=2"	"5"	"1"	"2"	"1"	"304"	"33.8"	"5.55"	"289.92"	"2.67"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00017, Pf00018, Pf07653"	"1398"	"ENSG00000167193"	"CRK"	"A8MWE8; B0LPE8; D3DTH6; hsa:1398; P46108; Q96GA9; Q96HJ0"	"Integrin-mediated cell adhesion; Androgen receptor network in prostate cancer; B cell receptor signaling pathway; Kit receptor signaling pathway; Focal adhesion; Hepatocyte growth factor receptor signaling; RAC1/PAK1/p38/MMP2 pathway; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Chemokine signaling pathway; Rett syndrome causing genes; EGF/EGFR signaling pathway; Gastrin signaling pathway; Insulin signaling; Regulation of actin cytoskeleton; GDNF signaling; Interferon type I signaling pathways; ErbB signaling pathway; T-cell receptor signaling pathway"	"FCGR3A-mediated phagocytosis; Regulation of signaling by CBL; Regulation of actin dynamics for phagocytic cup formation; Downstream signal transduction; VEGFA-VEGFR2 Pathway; PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases; ARMS-mediated activation; p130Cas linkage to MAPK signaling for integrins; MET activates RAP1 and RAC1; MET receptor recycling"	"30"	"0"	"20.4"	"39.2"	"37.7"	"16.3"	"39.3"	"18.9"	"40.5"	"45.4"	"51.9"	"57.5"	"90.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UNF0"	"Protein kinase C and casein kinase substrate in neurons protein 2 OS=Homo sapiens OX=9606 GN=PACSIN2 PE=1 SV=2"	"2"	"1"	"2"	"1"	"486"	"55.7"	"5.20"	"304.84"	"2.67"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00018, Pf00611"	"11252"	"ENSG00000100266"	"PACSIN2"	"hsa:11252; O95921; Q96HV9; Q9H0D3; Q9NPN1; Q9UNF0; Q9Y4V2"	""	"Clathrin-mediated endocytosis"	"1"	"0"	"51.7"	"110.1"	"105.1"	"52.6"	"121.5"	"74.8"	"123.0"	"94.2"	"183.4"	"322.3"	"573.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2L5"	"Trafficking protein particle complex subunit 8 OS=Homo sapiens OX=9606 GN=TRAPPC8 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1435"	"160.9"	"6.87"	"285.89"	"2.67"	"1"	"1"	"cell organization and biogenesis;transport"	"cytosol;ER/Golgi;other cell component"	""	"Pf12739"	"22878"	"ENSG00000153339"	"TRAPPC8"	"A0JP15; B3KME5; hsa:22878; Q9H0L2; Q9Y2L5"	""	"RAB GEFs exchange GTP for GDP on RABs"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A1A4S6"	"Rho GTPase-activating protein 10 OS=Homo sapiens OX=9606 GN=ARHGAP10 PE=1 SV=1"	"1"	"1"	"1"	"1"	"786"	"89.3"	"7.18"	""	"2.66"	""	"1"	"cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"enzyme regulator activity"	"Pf00169, Pf00620, Pf14604, Pf16746"	"79658"	"ENSG00000071205"	"ARHGAP10"	"A1A4S6; A1L0S5; hsa:79658; Q2VPC4; Q2VPC5; Q96EV3; Q96S75"	"Ectoderm differentiation; Ectoderm differentiation"	"Regulation of PAK-2p34 activity by PS-GAP/RHG10; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle"	"6"	"0"	"4.4"	"10.1"	"11.9"	"4.2"	"13.2"	"6.0"	"18.2"	"19.2"	"69.4"	"142.3"	"192.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKV3"	"Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2"	"2"	"2"	"2"	"2"	"1341"	"151.8"	"6.43"	"340.16"	"2.66"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02037, Pf16294"	"22985"	"ENSG00000100813"	"ACIN1"	"B2RTT4; D3DS45; hsa:22985; O75158; Q9UG91; Q9UKV1; Q9UKV2; Q9UKV3"	""	"mRNA Splicing - Major Pathway; Apoptotic cleavage of cellular proteins"	"2"	"0"	"30.1"	"102.3"	"76.6"	"22.5"	"72.6"	"26.5"	"49.5"	"41.9"	"62.9"	"69.4"	"144.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82930"	"28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2"	"4"	"1"	"2"	"1"	"218"	"25.6"	"9.98"	"336.75"	"2.66"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf16053"	"65993"	"ENSG00000074071"	"MRPS34"	"hsa:65993; P82930; Q9BVI7"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"54.4"	"116.0"	"119.6"	"40.6"	"112.5"	"56.3"	"91.4"	"70.2"	"97.6"	"128.3"	"155.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NZI7"	"Upstream-binding protein 1 OS=Homo sapiens OX=9606 GN=UBP1 PE=1 SV=1"	"4"	"2"	"3"	"2"	"540"	"60.5"	"6.35"	"275.07"	"2.65"	"1"	"2"	"RNA metabolism OR transcription;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04516, Pf18016"	"7342"	"ENSG00000153560"	"UBP1"	"hsa:7342; Q68CT0; Q86Y57; Q9H8V0; Q9NZI7; Q9UD76; Q9UD78"	""	""	"0"	"0"	"29.0"	"48.3"	"53.1"	"23.0"	"56.0"	"28.7"	"73.4"	"86.1"	"182.7"	"254.0"	"411.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4L1"	"Hypoxia up-regulated protein 1 OS=Homo sapiens OX=9606 GN=HYOU1 PE=1 SV=1"	"2"	"2"	"3"	"2"	"999"	"111.3"	"5.22"	"556.23"	"2.65"	"2"	"1"	"stress response;transport;other biological processes"	"non-structural extracellular;ER/Golgi;other cell component"	"other molecular function"	"Pf00012"	"10525"	"ENSG00000149428; ENSG00000280682"	"HYOU1"	"A8C1Z0; B7Z909; hsa:10525; Q2I204; Q53H25; Q9Y4L1"	"VEGFA-VEGFR2 signaling; 11p11.2 copy number variation syndrome"	"XBP1(S) activates chaperone genes; Scavenging by Class F Receptors"	"4"	"0"	"98.8"	"509.4"	"403.2"	"72.1"	"337.7"	"121.5"	"185.3"	"130.0"	"204.0"	"280.2"	"473.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5RKV6"	"Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1"	"3"	"1"	"2"	"1"	"272"	"28.2"	"6.28"	"307.81"	"2.65"	"1"	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	""	"Pf01138"	"118460"	"ENSG00000223496"	"EXOSC6"	"hsa:118460; Q5RKV6"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	"6"	"0"	"86.7"	"156.8"	"154.2"	"79.0"	"167.0"	"102.7"	"161.6"	"129.9"	"179.0"	"214.9"	"292.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UNQ2"	"Probable dimethyladenosine transferase OS=Homo sapiens OX=9606 GN=DIMT1 PE=1 SV=1"	"3"	"1"	"2"	"1"	"313"	"35.2"	"9.99"	"292.19"	"2.64"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00398"	"27292"	"ENSG00000086189"	"DIMT1"	"hsa:27292; O76025; Q9BU77; Q9UES1; Q9UNQ2"	""	"rRNA modification in the nucleus and cytosol"	"1"	"0"	"36.9"	"99.0"	"111.0"	"45.4"	"107.9"	"48.7"	"113.1"	"91.0"	"145.6"	"167.1"	"216.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P02788"	"Lactotransferrin OS=Homo sapiens OX=9606 GN=LTF PE=1 SV=6"	"2"	"1"	"4"	"1"	"710"	"78.1"	"8.12"	"699.64"	"2.64"	"1"	"1"	"protein metabolism;stress response;transport;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00405"	"4057"	"ENSG00000012223"	"LTF"	"A8K9U8; B2MV13; B7Z4X2; E7EQH5; hsa:4057; O00756; P02788; Q16780; Q16785; Q16786; Q16789; Q5DSM0; Q8IU92; Q8IZH6; Q8TCD2; Q96KZ4; Q96KZ5; Q9H1Z3; Q9UCY5"	"Male infertility"	"Neutrophil degranulation; Amyloid fiber formation; Mtb iron assimilation by chelation; Metal sequestration by antimicrobial proteins"	"6"	"0"	"27.3"	"52.6"	"58.7"	"28.6"	"64.9"	"41.1"	"53.4"	"52.7"	"657.2"	"106.9"	"119.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q05519"	"Serine/arginine-rich splicing factor 11 OS=Homo sapiens OX=9606 GN=SRSF11 PE=1 SV=1"	"2"	"1"	"2"	"1"	"484"	"53.5"	"10.52"	"369.95"	"2.64"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00076"	"9295"	"ENSG00000116754"	"SRSF11"	"hsa:9295; Q05519; Q5T758; Q8IWE6"	""	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript"	"5"	"0"	"30.4"	"172.9"	"194.6"	"32.3"	"157.1"	"40.3"	"97.7"	"76.4"	"120.9"	"188.2"	"258.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15031"	"Probable leucine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=LARS2 PE=1 SV=2"	"1"	"1"	"2"	"1"	"903"	"101.9"	"8.22"	"339.50"	"2.64"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00133, Pf08264"	"23395"	"ENSG00000011376"	"LARS2"	"hsa:23395; Q15031"	"Amino acid metabolism; IL-18 signaling pathway; Primary ovarian insufficiency"	"Mitochondrial tRNA aminoacylation"	"4"	"0"	"50.9"	"148.0"	"145.4"	"32.2"	"108.6"	"51.8"	"155.1"	"111.6"	"182.7"	"216.3"	"353.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60343"	"TBC1 domain family member 4 OS=Homo sapiens OX=9606 GN=TBC1D4 PE=1 SV=2"	"2"	"2"	"3"	"2"	"1298"	"146.5"	"7.01"	"660.33"	"2.64"	"2"	"1"	"transport;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity"	"Pf00566, Pf00640, Pf11830"	"9882"	"ENSG00000136111"	"TBC1D4"	"A7E2X8; B4DU25; B4E235; B6ETN8; B6ETN9; hsa:9882; O60343; Q5W0B9; Q68D14"	"Ciliary landscape; Thyroid hormones production and peripheral downstream signaling effects; Insulin signaling"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"	"4"	"0"	"83.2"	"315.2"	"289.7"	"64.2"	"255.6"	"121.8"	"133.0"	"80.7"	"149.0"	"167.7"	"300.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WUF5"	"RelA-associated inhibitor OS=Homo sapiens OX=9606 GN=PPP1R13L PE=1 SV=4"	"1"	"1"	"2"	"1"	"828"	"89.0"	"6.81"	"282.21"	"2.64"	"1"	"1"	"RNA metabolism OR transcription;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf12796, Pf14604"	"10848"	"ENSG00000104881"	"PPP1R13L"	"hsa:10848; Q2PNZ9; Q5DU71; Q5I1X4; Q6P1R7; Q6PKF8; Q8WUF5; Q9Y290"	"IL-18 signaling pathway"	"Regulation of TP53 Activity through Association with Co-factors"	"2"	"0"	"7.5"	"16.8"	"12.8"	"10.8"	"16.3"	"7.7"	"26.7"	"26.5"	"26.1"	"28.7"	"35.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKE5"	"TRAF2 and NCK-interacting protein kinase OS=Homo sapiens OX=9606 GN=TNIK PE=1 SV=1"	"2"	"2"	"3"	"1"	"1360"	"154.8"	"7.17"	"519.68"	"2.64"	"2"	"1"	"cell-cell signaling;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00780"	"23043"	"ENSG00000154310"	"TNIK"	"A7E2A3; A8K4U1; D3DNQ6; hsa:23043; O60298; Q8WUY7; Q9UKD8; Q9UKD9; Q9UKE0; Q9UKE1; Q9UKE2; Q9UKE3; Q9UKE4; Q9UKE5"	"Hippo-YAP signaling; Pleural mesothelioma"	"Oxidative Stress Induced Senescence"	"3"	"0"	"21.4"	"78.8"	"87.0"	"32.5"	"70.1"	"28.0"	"111.8"	"182.4"	"212.9"	"203.4"	"278.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBE0"	"SUMO-activating enzyme subunit 1 OS=Homo sapiens OX=9606 GN=SAE1 PE=1 SV=1"	"3"	"1"	"2"	"1"	"346"	"38.4"	"5.30"	"260.86"	"2.64"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00899"	"10055"	"ENSG00000142230"	"SAE1"	"B2RDP5; B3KMQ2; F5GXX7; G3XAK6; hsa:10055; O95717; Q9P020; Q9UBE0"	""	"SUMO is conjugated to E1 (UBA2:SAE1); SUMO is transferred from E1 to E2 (UBE2I, UBC9)"	"2"	"0"	"10.3"	"123.3"	"88.0"	"9.2"	"100.4"	"16.7"	"28.2"	"22.0"	"25.0"	"33.9"	"82.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q93096"	"Protein tyrosine phosphatase type IVA 1 OS=Homo sapiens OX=9606 GN=PTP4A1 PE=1 SV=2"	"11"	"2"	"3"	"2"	"173"	"19.8"	"8.97"	"693.89"	"2.63"	"2"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00782"	"7803"	"ENSG00000112245"	"PTP4A1"	"B2R6C8; hsa:7803; O00648; Q49A54; Q93096"	""	""	"0"	"0"	"79.9"	"191.9"	"176.5"	"54.7"	"161.4"	"81.3"	"129.1"	"89.8"	"136.8"	"202.6"	"345.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P02808"	"Statherin OS=Homo sapiens OX=9606 GN=STATH PE=1 SV=2"	"48"	"1"	"1"	"1"	"62"	"7.3"	"8.47"	""	"2.63"	""	"1"	"stress response;transport;other biological processes"	"non-structural extracellular"	"extracellular structural activity;bone, tooth or skin structural activity;other molecular function"	"Pf03875"	"6779"	"ENSG00000126549; ENSG00000282891"	"STATH"	"A6NKE9; B2R4F8; hsa:6779; P02808"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31483"	"Nucleolysin TIA-1 isoform p40 OS=Homo sapiens OX=9606 GN=TIA1 PE=1 SV=3"	"6"	"2"	"3"	"1"	"386"	"42.9"	"7.74"	"783.88"	"2.63"	"2"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"7072"	"ENSG00000116001"	"TIA1"	"hsa:7072; P31483; Q53SS9; Q96B58"	""	"FGFR2 alternative splicing"	"1"	"0"	"24.7"	"28.2"	"31.7"	"29.8"	"44.6"	"25.2"	"40.0"	"43.4"	"42.7"	"48.0"	"63.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92925"	"SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 OS=Homo sapiens OX=9606 GN=SMARCD2 PE=1 SV=3"	"2"	"1"	"2"	"1"	"531"	"58.9"	"9.64"	"260.21"	"2.63"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf02201"	"6603"	"ENSG00000108604"	"SMARCD2"	"A5PLL5; A6NNQ7; B4DV56; B4E1R6; hsa:6603; Q7L2I6; Q92925; Q9UHZ1"	"Androgen receptor network in prostate cancer; Tumor suppressor activity of SMARCB1; Thermogenesis; Kleefstra syndrome"	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; RMTs methylate histone arginines"	"6"	"0"	"5.2"	"14.5"	"12.9"	"4.2"	"15.7"	"4.6"	"10.2"	"9.4"	"9.9"	"19.2"	"19.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H2U2"	"Inorganic pyrophosphatase 2, mitochondrial OS=Homo sapiens OX=9606 GN=PPA2 PE=1 SV=2"	"2"	"1"	"2"	"1"	"334"	"37.9"	"7.39"	"343.23"	"2.63"	"1"	"1"	"other metabolic processes;other biological processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf00719"	"27068"	"ENSG00000138777"	"PPA2"	"B4DLP7; F8WDN9; hsa:27068; I6L9B6; Q4W5E9; Q6PG51; Q8TBW0; Q96E55; Q9H0T0; Q9H2U2; Q9NX37; Q9P033; Q9ULX0"	""	"Mitochondrial tRNA aminoacylation; Pyrophosphate hydrolysis"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P31949"	"Protein S100-A11 OS=Homo sapiens OX=9606 GN=S100A11 PE=1 SV=2"	"10"	"1"	"2"	"1"	"105"	"11.7"	"7.12"	"289.33"	"2.63"	"1"	"1"	"signal transduction;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00036, Pf01023"	"6282"	"ENSG00000163191"	"S100A11"	"hsa:6282; P31949; Q5VTK0"	""	"Neutrophil degranulation"	"1"	"0"	"4.0"	"28.7"	"25.8"	"3.5"	"18.7"	"8.0"	"12.3"	"7.8"	"10.2"	"15.0"	"24.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z7F7"	"39S ribosomal protein L55, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL55 PE=1 SV=1"	"6"	"1"	"2"	"1"	"128"	"15.1"	"11.15"	"374.60"	"2.62"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;other cell component"	"other molecular function"	"Pf09776"	"128308"	"ENSG00000162910"	"MRPL55"	"hsa:128308; Q5TBY3; Q5TBY6; Q6UWI8; Q7Z7F7"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"78.0"	"230.6"	"185.5"	"74.3"	"142.6"	"82.6"	"96.6"	"85.4"	"146.1"	"197.3"	"319.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92879"	"CUGBP Elav-like family member 1 OS=Homo sapiens OX=9606 GN=CELF1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"486"	"52.0"	"8.46"	"364.11"	"2.62"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"10658"	"ENSG00000149187"	"CELF1"	"B4E2U5; D3DQS0; F8W940; hsa:10658; Q4LE52; Q92879; Q9NP83; Q9NR06"	"Adipogenesis; mRNA processing"	""	"2"	"0"	"35.8"	"126.8"	"114.3"	"23.7"	"100.2"	"37.2"	"54.3"	"45.1"	"66.7"	"98.8"	"142.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P17655"	"Calpain-2 catalytic subunit OS=Homo sapiens OX=9606 GN=CAPN2 PE=1 SV=6"	"1"	"1"	"2"	"1"	"700"	"79.9"	"4.98"	"306.73"	"2.62"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00648, Pf01067, Pf13833"	"824"	"ENSG00000162909"	"CAPN2"	"A6NDG7; B7ZA96; E7ES58; hsa:824; P17655; Q16738; Q6PJT3; Q8WU26; Q9HBB1"	"Integrin-mediated cell adhesion; Alzheimer's disease and miRNA effects; Focal adhesion; VEGFA-VEGFR2 signaling; Alzheimer's disease"	"Degradation of the extracellular matrix; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"	"7"	"0"	"147.0"	"317.4"	"283.1"	"120.5"	"251.9"	"168.1"	"201.8"	"183.3"	"277.0"	"329.0"	"548.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13045"	"Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2"	"1"	"1"	"2"	"1"	"1269"	"144.7"	"6.05"	"258.07"	"2.62"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00626, Pf12799, Pf13855"	"2314"	"ENSG00000177731; ENSG00000284571"	"FLII"	"B4DIL0; F5H407; hsa:2314; J3QLG3; Q13045"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"9.2"	"41.2"	"35.1"	"9.5"	"32.8"	"11.9"	"19.7"	"12.9"	"26.1"	"29.3"	"45.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TF72"	"Protein Shroom3 OS=Homo sapiens OX=9606 GN=SHROOM3 PE=1 SV=2"	"0"	"1"	"2"	"1"	"1996"	"216.7"	"7.80"	"240.53"	"2.62"	"1"	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf00595, Pf08687, Pf08688"	"57619"	"ENSG00000138771"	"SHROOM3"	"hsa:57619; Q5QTQ3; Q6ZRW3; Q8TF72; Q96IR9; Q9P247"	""	""	"0"	"0"	"241.9"	"253.4"	"342.9"	"200.2"	"316.2"	"241.9"	"417.3"	"273.0"	"362.4"	"347.3"	"459.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14676"	"Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3"	"1"	"1"	"1"	"1"	"2089"	"226.5"	"5.47"	""	"2.62"	""	"1"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	""	"Pf00498, Pf16770"	"9656"	"ENSG00000137337; ENSG00000206481; ENSG00000224587; ENSG00000225589; ENSG00000228575; ENSG00000231135; ENSG00000234012; ENSG00000237095"	"MDC1"	"A2AB04; A2BF04; A2RRA8; A7YY86; B0S8A2; hsa:9656; Q0EFC2; Q14676; Q2L6H7; Q2TAZ4; Q5JP55; Q5JP56; Q5ST83; Q68CQ3; Q86Z06; Q96QC2"	"ATM signaling in development and disease ; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; NIPBL role in DNA damage - Cornelia de Lange syndrome"	"Processing of DNA double-strand break ends; SUMOylation of DNA damage response and repair proteins; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; TP53 Regulates Transcription of DNA Repair Genes; G2/M DNA damage checkpoint; Nonhomologous End-Joining (NHEJ)"	"9"	"0"	"21.3"	"15.6"	"26.7"	"14.6"	"30.2"	"21.6"	"33.2"	"19.9"	"33.1"	"32.4"	"30.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P47755"	"F-actin-capping protein subunit alpha-2 OS=Homo sapiens OX=9606 GN=CAPZA2 PE=1 SV=3"	"6"	"1"	"2"	"1"	"286"	"32.9"	"5.85"	"287.46"	"2.61"	"1"	"1"	"cell organization and biogenesis"	"non-structural extracellular;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf01267"	"830"	"ENSG00000198898"	"CAPZA2"	"B4DG50; hsa:830; P47755"	""	"MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Sensory processing of sound by inner hair cells of the cochlea; Factors involved in megakaryocyte development and platelet production; Advanced glycosylation endproduct receptor signaling"	"7"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75689"	"Arf-GAP with dual PH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ADAP1 PE=1 SV=2"	"5"	"2"	"3"	"2"	"374"	"43.4"	"8.97"	"541.47"	"2.61"	"2"	"1"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf01412"	"11033"	"ENSG00000105963"	"ADAP1"	"A4D2Q2; B3KRZ4; B4DVA6; F6XZ68; H7C2Q4; hsa:11033; O75689"	""	"Nuclear signaling by ERBB4"	"1"	"0"	"37.8"	"53.8"	"66.1"	"28.7"	"77.3"	"46.0"	"80.8"	"54.0"	"86.4"	"166.8"	"349.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30044"	"Peroxiredoxin-5, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX5 PE=1 SV=4"	"12"	"2"	"3"	"2"	"214"	"22.1"	"8.70"	"694.42"	"2.61"	"2"	"1"	"other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf08534"	"25824"	"ENSG00000126432"	"PRDX5"	"A6NC19; A6NG06; B7ZLJ4; B7ZVW3; hsa:25824; P30044; Q14CK0; Q6IAF2; Q9UBU5; Q9UJU4; Q9UKX4"	"Selenium micronutrient network"	""	"1"	"0"	"39.3"	"319.5"	"265.2"	"36.3"	"257.2"	"78.7"	"90.3"	"50.2"	"96.5"	"110.2"	"226.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBQ0"	"Vacuolar protein sorting-associated protein 29 OS=Homo sapiens OX=9606 GN=VPS29 PE=1 SV=1"	"4"	"1"	"2"	"1"	"182"	"20.5"	"6.79"	"275.56"	"2.61"	"1"	"1"	"transport"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf12850"	"51699"	"ENSG00000111237"	"VPS29"	"hsa:51699; Q502Y5; Q6FIF8; Q6IAH3; Q9H0W0; Q9NRP1; Q9NRU7; Q9UBQ0"	""	"WNT ligand biogenesis and trafficking"	"1"	"0"	"74.1"	"167.7"	"185.8"	"58.7"	"180.6"	"81.4"	"146.5"	"99.7"	"165.5"	"188.6"	"301.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P00403"	"Cytochrome c oxidase subunit 2 OS=Homo sapiens OX=9606 GN=MT-CO2 PE=1 SV=1"	"13"	"2"	"3"	"2"	"227"	"25.5"	"4.82"	"497.87"	"2.61"	"2"	"1"	"other metabolic processes;stress response;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00116, Pf02790"	"4513"	"ENSG00000198712"	"MT-CO2"	"hsa:4513; P00403; Q37526"	"Electron transport chain: OXPHOS system in mitochondria; Endothelin pathways; EGF/EGFR signaling pathway; Nonalcoholic fatty liver disease; Neuroinflammation; Mitochondrial complex IV assembly; CCL18 signaling pathway"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"10"	"0"	"20.0"	"52.9"	"56.3"	"16.6"	"60.3"	"25.1"	"39.5"	"28.4"	"39.1"	"61.1"	"69.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6MZP7"	"Protein lin-54 homolog OS=Homo sapiens OX=9606 GN=LIN54 PE=1 SV=3"	"2"	"1"	"2"	"1"	"749"	"79.4"	"9.01"	"297.20"	"2.60"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03638"	"132660"	"ENSG00000189308"	"LIN54"	"hsa:132660; Q32M68; Q32M69; Q6MZP7; Q6N071; Q76B60"	"DYRK1A involvement regarding cell proliferation in brain development"	"G1/S-Specific Transcription; Polo-like kinase mediated events; Cyclin E associated events during G1/S transition ; Transcription of E2F targets under negative control by DREAM complex; Cyclin A:Cdk2-associated events at S phase entry; Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"	"8"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9ULX6"	"A-kinase anchor protein 8-like OS=Homo sapiens OX=9606 GN=AKAP8L PE=1 SV=4"	"2"	"1"	"2"	"1"	"646"	"71.6"	"5.05"	"326.12"	"2.60"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04988"	"26993"	"ENSG00000011243"	"AKAP8L"	"B4DJ74; B5BU90; hsa:26993; O94792; Q96J58; Q9NRQ0; Q9UGM0; Q9ULX6"	""	"Formation of WDR5-containing histone-modifying complexes"	"1"	"0"	"12.4"	"26.9"	"27.9"	"13.1"	"26.4"	"12.3"	"19.1"	"15.9"	"22.7"	"36.8"	"51.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00422"	"Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1"	"5"	"1"	"2"	"1"	"153"	"17.6"	"9.35"	"289.34"	"2.59"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf06487"	"10284"	"ENSG00000150459"	"SAP18"	"B2R494; hsa:10284; O00422; Q2TTR4; Q6IAW9; Q8N606; Q9UF14; X6RAL5"	"Hedgehog signaling pathway"	"Potential therapeutics for SARS; HDACs deacetylate histones; NoRC negatively regulates rRNA expression; mRNA Splicing - Major Pathway"	"5"	"0"	"57.8"	"244.4"	"236.0"	"49.9"	"175.0"	"70.3"	"119.8"	"99.0"	"168.3"	"235.0"	"427.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6NSI4"	"RPA-related protein RADX OS=Homo sapiens OX=9606 GN=RADX PE=1 SV=2"	"2"	"1"	"2"	"1"	"855"	"97.5"	"8.41"	"304.47"	"2.59"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf17659"	"55086"	"ENSG00000147231"	"RADX"	"H7BY89; hsa:55086; Q4G0L7; Q5JQS1; Q5JRF9; Q6NSI4; Q6PHY5; Q6PII9; Q6PJU8; Q9H7W5; Q9NWA6"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2R5"	"28S ribosomal protein S17, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS17 PE=1 SV=1"	"8"	"1"	"1"	"1"	"130"	"14.5"	"9.85"	""	"2.59"	""	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity"	"Pf00366"	"51373"	"ENSG00000239789"	"MRPS17"	"hsa:51373; Q86X15; Q9Y2R5"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"33.6"	"60.5"	"71.7"	"30.8"	"75.2"	"33.8"	"72.5"	"65.6"	"85.2"	"111.6"	"147.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95299"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFA10 PE=1 SV=1"	"6"	"2"	"3"	"2"	"355"	"40.7"	"8.48"	"659.53"	"2.59"	"2"	"1"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion;other cell component"	"transporter activity"	"Pf01712"	"4705"	"ENSG00000130414"	"NDUFA10"	"hsa:4705; O95299; Q8WXC9"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; 2q37 copy number variation syndrome; Oxidative phosphorylation"	"Complex I biogenesis"	"6"	"0"	"37.8"	"102.1"	"106.3"	"45.4"	"93.2"	"51.4"	"90.7"	"70.5"	"110.6"	"144.3"	"222.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96G46"	"tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like OS=Homo sapiens OX=9606 GN=DUS3L PE=1 SV=2"	"2"	"1"	"1"	"1"	"650"	"72.5"	"8.05"	""	"2.59"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	""	"other molecular function"	"Pf01207, Pf18044"	"56931"	"ENSG00000141994"	"DUS3L"	"hsa:56931; Q96G46; Q96HM5; Q9BSU4; Q9H877; Q9NPR1"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13823"	"Nucleolar GTP-binding protein 2 OS=Homo sapiens OX=9606 GN=GNL2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"731"	"83.6"	"9.25"	"333.36"	"2.59"	"1"	"1"	"other biological processes"	"nucleus"	"other molecular function"	"Pf01926, Pf08153"	"29889"	"ENSG00000134697"	"GNL2"	"hsa:29889; Q13823; Q9BWN7"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09001"	"39S ribosomal protein L3, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL3 PE=1 SV=1"	"2"	"1"	"2"	"1"	"348"	"38.6"	"9.48"	"282.81"	"2.59"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00297"	"11222"	"ENSG00000114686"	"MRPL3"	"hsa:11222; P09001; Q6IBT2"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"57.5"	"168.9"	"145.3"	"58.3"	"117.2"	"63.9"	"67.2"	"51.6"	"91.8"	"102.9"	"179.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q63HR2"	"Tensin-2 OS=Homo sapiens OX=9606 GN=TNS2 PE=1 SV=2"	"1"	"1"	"1"	"1"	"1409"	"152.5"	"8.35"	""	"2.59"	""	"1"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00017, Pf08416, Pf10409"	"23371"	"ENSG00000111077"	"TNS2"	"A2VDF2; A2VDF3; A2VDI8; A5PKY4; hsa:23371; Q2NL80; Q63HR2; Q76MW6; Q7Z5T9; Q8NFF9; Q8NFG0; Q96P25; Q9NT29; Q9UPS7"	""	""	"0"	"0"	"24.9"	"47.7"	"49.7"	"17.6"	"46.6"	"24.3"	"36.4"	"32.3"	"46.1"	"96.6"	"164.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NZB2"	"Constitutive coactivator of PPAR-gamma-like protein 1 OS=Homo sapiens OX=9606 GN=FAM120A PE=1 SV=2"	"1"	"1"	"2"	"1"	"1118"	"121.8"	"8.88"	"270.11"	"2.59"	"1"	"1"	""	"plasma membrane;other membranes;cytosol;nucleus"	""	""	"23196"	"ENSG00000048828"	"FAM120A"	"A6NGU0; C4AMC6; hsa:23196; O60649; Q14688; Q4VXF4; Q4VXF5; Q4VXG2; Q86V69; Q96I21; Q9NZB1; Q9NZB2"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"45.0"	"94.5"	"91.1"	"39.2"	"93.7"	"56.7"	"81.0"	"69.8"	"93.1"	"116.9"	"137.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5J9"	"Mitochondrial import inner membrane translocase subunit Tim8 B OS=Homo sapiens OX=9606 GN=TIMM8B PE=1 SV=1"	"8"	"1"	"2"	"1"	"83"	"9.3"	"5.12"	"283.44"	"2.59"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf02953"	"26521"	"ENSG00000150779"	"TIMM8B"	"B0YJA5; hsa:26521; Q3KQS9; Q9UN04; Q9Y5J9"	""	"Mitochondrial protein import"	"1"	"0"	"28.5"	"106.9"	"131.5"	"33.6"	"109.2"	"47.4"	"122.6"	"86.0"	"168.4"	"255.1"	"496.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14976"	"Cyclin-G-associated kinase OS=Homo sapiens OX=9606 GN=GAK PE=1 SV=2"	"1"	"1"	"1"	"1"	"1311"	"143.1"	"5.73"	""	"2.58"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;ER/Golgi;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf10409"	"2580"	"ENSG00000178950"	"GAK"	"hsa:2580; O14976; Q5U4P5; Q9BVY6"	""	"Golgi Associated Vesicle Biogenesis; Clathrin-mediated endocytosis"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BPX6"	"Calcium uptake protein 1, mitochondrial OS=Homo sapiens OX=9606 GN=MICU1 PE=1 SV=1"	"3"	"1"	"2"	"1"	"476"	"54.3"	"8.41"	"237.49"	"2.58"	"1"	"1"	"cell organization and biogenesis;stress response;transport;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf13202"	"10367"	"ENSG00000107745"	"MICU1"	"A8MV96; B3KN20; B4DJH9; B4DPI1; B5MBY3; D3YTJ3; hsa:10367; O75785; Q9BPX6; Q9H9N6; Q9UFX0"	""	"Processing of SMDT1"	"2"	"0"	"20.4"	"23.2"	"26.6"	"18.3"	"27.7"	"21.7"	"36.7"	"26.1"	"40.9"	"50.1"	"50.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99816"	"Tumor susceptibility gene 101 protein OS=Homo sapiens OX=9606 GN=TSG101 PE=1 SV=2"	"3"	"1"	"2"	"1"	"390"	"43.9"	"6.46"	"312.16"	"2.58"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05743, Pf09454"	"7251"	"ENSG00000074319"	"TSG101"	"hsa:7251; Q99816; Q9BUM5"	"Ebola virus infection in host; 7q11.23 copy number variation syndrome"	"HCMV Late Events; Budding and maturation of HIV virion; Endosomal Sorting Complex Required For Transport (ESCRT); Late endosomal microautophagy; Membrane binding and targetting of GAG proteins"	"7"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00487"	"26S proteasome non-ATPase regulatory subunit 14 OS=Homo sapiens OX=9606 GN=PSMD14 PE=1 SV=1"	"7"	"3"	"5"	"3"	"310"	"34.6"	"6.52"	"837.62"	"2.58"	"3"	"2"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf01398, Pf13012"	"10213"	"ENSG00000115233"	"PSMD14"	"B3KNW2; hsa:10213; O00176; O00487"	"Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"Antigen processing: Ubiquitination & Proteasome degradation; FCERI mediated NF-kB activation; Downstream TCR signaling; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Metalloprotease DUBs"	"64"	"0"	"435.6"	"721.7"	"820.4"	"347.3"	"783.0"	"500.0"	"541.7"	"370.5"	"546.4"	"634.0"	"1026.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NFH3"	"Nucleoporin Nup43 OS=Homo sapiens OX=9606 GN=NUP43 PE=1 SV=1"	"3"	"1"	"2"	"1"	"380"	"42.1"	"5.63"	"289.05"	"2.58"	"1"	"1"	"cell cycle OR cell proliferation;transport;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf00400"	"348995"	"ENSG00000120253"	"NUP43"	"B4E2F0; hsa:348995; Q8NFH3; Q9H8S0"	""	"Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Regulation of HSF1-mediated heat shock response; ISG15 antiviral mechanism; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Vpr-mediated nuclear import of PICs; SUMOylation of DNA damage response and repair proteins; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; RHO GTPases Activate Formins; Transport of Mature mRNA derived from an Intron-Containing Transcript; tRNA processing in the nucleus; HCMV Late Events; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; HCMV Early Events; EML4 and NUDC in mitotic spindle formation; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; snRNP Assembly; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); SARS-CoV-2 activates/modulates innate and adaptive immune responses; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Postmitotic nuclear pore complex (NPC) reformation"	"35"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NQT8"	"Kinesin-like protein KIF13B OS=Homo sapiens OX=9606 GN=KIF13B PE=1 SV=2"	"1"	"1"	"1"	"1"	"1826"	"202.7"	"5.88"	""	"2.57"	""	"1"	"transport;signal transduction;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225, Pf00498, Pf01302, Pf12423, Pf12473, Pf16183"	"23303"	"ENSG00000197892"	"KIF13B"	"B4DGY5; B5MC45; F8VPJ2; hsa:23303; O75134; Q9BYJ6; Q9NQT8"	""	"COPI-dependent Golgi-to-ER retrograde traffic; Kinesins"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P43034"	"Platelet-activating factor acetylhydrolase IB subunit alpha OS=Homo sapiens OX=9606 GN=PAFAH1B1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"410"	"46.6"	"7.37"	"287.83"	"2.57"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400, Pf08513"	"5048"	"ENSG00000007168"	"PAFAH1B1"	"B2R7Q7; hsa:5048; P43034; Q8WZ88; Q8WZ89"	"Wnt signaling pathway and pluripotency; Ciliary landscape; Neurogenesis regulation in the olfactory epithelium"	"Resolution of Sister Chromatid Cohesion; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Separation of Sister Chromatids; RHO GTPases Activate Formins; COPI-independent Golgi-to-ER retrograde traffic; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"17"	"0"	"45.0"	"198.4"	"150.1"	"33.7"	"129.1"	"37.5"	"103.0"	"95.2"	"124.9"	"189.4"	"362.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UK33"	"Zinc finger protein 580 OS=Homo sapiens OX=9606 GN=ZNF580 PE=1 SV=1"	"10"	"1"	"2"	"1"	"172"	"18.7"	"10.08"	"290.87"	"2.57"	"1"	"1"	"RNA metabolism OR transcription;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00096"	"51157"	"ENSG00000213015"	"ZNF580"	"B2RC05; hsa:51157; Q9NPP7; Q9UK33"	""	""	"0"	"0"	"14.2"	"24.8"	"37.9"	"16.1"	"30.4"	"13.4"	"23.9"	"23.0"	"44.9"	"55.9"	"61.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NB49"	"Phospholipid-transporting ATPase IG OS=Homo sapiens OX=9606 GN=ATP11C PE=1 SV=3"	"1"	"1"	"2"	"1"	"1132"	"129.4"	"6.67"	"247.89"	"2.56"	"1"	"1"	"cell organization and biogenesis;transport"	"plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf00122, Pf13246, Pf16209, Pf16212"	"286410"	"ENSG00000101974"	"ATP11C"	"hsa:286410; Q5JT69; Q5JT70; Q5JT71; Q5JT72; Q5JT73; Q6ZND5; Q6ZU50; Q6ZUP7; Q70IJ9; Q70IK0; Q8NB49; Q8WX24"	"Complement system in neuronal development and plasticity"	"Ion transport by P-type ATPases"	"2"	"0"	"0.0"	"15.1"	"13.8"	"6.4"	"12.0"	"6.4"	"10.6"	"4.5"	"10.9"	"15.2"	"31.9"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6ZW49"	"PAX-interacting protein 1 OS=Homo sapiens OX=9606 GN=PAXIP1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1069"	"121.3"	"6.70"	"299.17"	"2.56"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	""	"Pf00533, Pf12738"	"22976"	"ENSG00000157212"	"PAXIP1"	"hsa:22976; O15404; Q6N099; Q6ZW49; Q6ZWH9; Q7Z315; Q86UN0; Q8N4P9; Q96HP2"	"16p11.2 proximal deletion syndrome; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; Kleefstra syndrome"	"Nonhomologous End-Joining (NHEJ); Activation of anterior HOX genes in hindbrain development during early embryogenesis; Formation of WDR5-containing histone-modifying complexes"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UHR5"	"SAP30-binding protein OS=Homo sapiens OX=9606 GN=SAP30BP PE=1 SV=1"	"4"	"1"	"2"	"1"	"308"	"33.9"	"4.84"	"270.29"	"2.56"	"1"	"1"	"other biological processes"	"cytoskeleton;nucleus"	""	"Pf07818"	"29115"	"ENSG00000161526"	"SAP30BP"	"B3KML7; hsa:29115; Q8N1R5; Q8TDR8; Q96D27; Q9UHR5"	""	"NoRC negatively regulates rRNA expression"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43143"	"Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2"	"1"	"1"	"1"	"1"	"795"	"90.9"	"7.46"	""	"2.56"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"1665"	"ENSG00000109606"	"DHX15"	"hsa:1665; O43143; Q9NQT7"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"17.5"	"41.2"	"36.2"	"14.6"	"35.9"	"20.7"	"26.3"	"15.2"	"24.8"	"42.4"	"58.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92783"	"Signal transducing adapter molecule 1 OS=Homo sapiens OX=9606 GN=STAM PE=1 SV=3"	"1"	"1"	"2"	"1"	"540"	"59.1"	"4.82"	"312.86"	"2.56"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;signal transduction;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00018, Pf00790, Pf02809"	"8027"	"ENSG00000136738"	"STAM"	"B0YJ99; D3DRU5; hsa:8027; Q8N6D9; Q92783"	"Vitamin D receptor pathway; VEGFA-VEGFR2 signaling; EGF/EGFR signaling pathway"	"Cargo recognition for clathrin-mediated endocytosis; RHOU GTPase cycle; Endosomal Sorting Complex Required For Transport (ESCRT); Metalloprotease DUBs; EGFR downregulation; Negative regulation of MET activity; InlB-mediated entry of Listeria monocytogenes into host cell"	"11"	"0"	"19.1"	"74.8"	"63.8"	"12.3"	"50.8"	"22.7"	"20.7"	"18.8"	"23.1"	"34.0"	"49.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60264"	"SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1"	"1"	"1"	"1"	"1"	"1052"	"121.8"	"8.09"	""	"2.56"	""	"1"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf09110, Pf09111"	"8467"	"ENSG00000153147"	"SMARCA5"	"hsa:8467; O60264"	""	"Deposition of new CENPA-containing nucleosomes at the centromere; B-WICH complex positively regulates rRNA expression; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; NoRC negatively regulates rRNA expression"	"4"	"0"	"13.5"	"47.2"	"42.3"	"16.9"	"40.6"	"18.3"	"35.2"	"25.1"	"40.0"	"47.8"	"69.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96KC8"	"DnaJ homolog subfamily C member 1 OS=Homo sapiens OX=9606 GN=DNAJC1 PE=1 SV=1"	"2"	"1"	"2"	"1"	"554"	"63.8"	"8.63"	"253.63"	"2.56"	"1"	"1"	"other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00226, Pf00249"	"64215"	"ENSG00000136770"	"DNAJC1"	"B0YIZ8; hsa:64215; Q5VX89; Q96KC8; Q9H6B8"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5T440"	"Putative transferase CAF17, mitochondrial OS=Homo sapiens OX=9606 GN=IBA57 PE=1 SV=1"	"3"	"1"	"1"	"1"	"356"	"38.1"	"9.83"	""	"2.55"	""	"1"	"cell organization and biogenesis;other metabolic processes"	"mitochondrion"	"other molecular function"	""	"200205"	"ENSG00000181873"	"IBA57"	"hsa:200205; Q5T440"	""	""	"0"	"0"	"91.7"	"69.4"	"110.2"	"38.8"	"113.7"	"61.6"	"131.3"	"100.5"	"112.1"	"195.7"	"202.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92947"	"Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1"	"3"	"1"	"2"	"1"	"438"	"48.1"	"8.06"	"302.86"	"2.55"	"1"	"1"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00441, Pf02770, Pf02771"	"2639"	"ENSG00000105607"	"GCDH"	"A8K2Z2; hsa:2639; O14719; Q92947"	"Fatty acid beta-oxidation; Tryptophan metabolism"	"Lysine catabolism"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14757"	"Serine/threonine-protein kinase Chk1 OS=Homo sapiens OX=9606 GN=CHEK1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"476"	"54.4"	"8.25"	"360.08"	"2.55"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"1111"	"ENSG00000149554"	"CHEK1"	"A8K934; B4DDD0; B4DSK3; B5BTY6; F5H7S4; H2BI51; hsa:1111; O14757"	"miRNA regulation of DNA damage response; Cell cycle; Retinoblastoma gene in cancer; ATR signaling; ATM signaling in development and disease ; DNA repair pathways, full network; TROP2 regulatory signaling; DNA damage response"	"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; TP53 Regulates Transcription of DNA Repair Genes; Regulation of TP53 Activity through Phosphorylation; Activation of ATR in response to replication stress; Transcriptional Regulation by E2F6; Signaling by SCF-KIT; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex"	"18"	"0"	"12.8"	"19.7"	"20.8"	"11.5"	"17.6"	"12.6"	"41.0"	"24.8"	"36.2"	"46.2"	"84.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13804"	"Electron transfer flavoprotein subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ETFA PE=1 SV=1"	"4"	"1"	"2"	"1"	"333"	"35.1"	"8.38"	"313.42"	"2.55"	"1"	"1"	"other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf00766, Pf01012"	"2108"	"ENSG00000140374"	"ETFA"	"B4DT43; hsa:2108; P13804; Q53XN3"	""	"Respiratory electron transport"	"1"	"0"	"7.9"	"40.2"	"30.1"	"5.1"	"24.9"	"8.8"	"16.3"	"10.3"	"12.8"	"26.3"	"30.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NFX7"	"Syntaxin-binding protein 6 OS=Homo sapiens OX=9606 GN=STXBP6 PE=1 SV=2"	"4"	"1"	"2"	"1"	"210"	"23.5"	"9.04"	"254.03"	"2.55"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;other cell component"	""	"Pf00957, Pf15277"	"29091"	"ENSG00000168952"	"STXBP6"	"D3DS78; hsa:29091; Q8N3H1; Q8N8D5; Q8NFX7; Q96GF3; Q9P008"	""	""	"0"	"0"	"103.3"	"131.9"	"167.3"	"85.2"	"151.6"	"94.0"	"167.0"	"122.7"	"197.9"	"299.1"	"481.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H7B4"	"Histone-lysine N-methyltransferase SMYD3 OS=Homo sapiens OX=9606 GN=SMYD3 PE=1 SV=4"	"4"	"2"	"3"	"1"	"428"	"49.1"	"7.25"	"509.04"	"2.54"	"2"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00856, Pf01753"	"64754"	"ENSG00000185420"	"SMYD3"	"A8K0P0; B1AN38; hsa:64754; Q86TL8; Q8N5Z6; Q96AI5; Q9H7B4"	"Histone modifications"	"PKMTs methylate histone lysines"	"2"	"0"	"23.2"	"44.2"	"51.6"	"20.9"	"47.2"	"30.7"	"51.6"	"45.4"	"64.9"	"143.8"	"273.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30622"	"CAP-Gly domain-containing linker protein 1 OS=Homo sapiens OX=9606 GN=CLIP1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1438"	"162.1"	"5.36"	"251.45"	"2.54"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01302, Pf16641"	"6249"	"ENSG00000130779"	"CLIP1"	"A0AVD3; hsa:6249; P30622; Q17RS4; Q29RG0"	"Microtubule cytoskeleton regulation"	"RHO GTPases Activate Formins; Resolution of Sister Chromatid Cohesion; Separation of Sister Chromatids; RHO GTPases activate IQGAPs; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"8"	"0"	"4.0"	"14.4"	"16.0"	"4.1"	"7.5"	"4.6"	"13.5"	"8.7"	"11.4"	"9.8"	"24.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86Y07"	"Serine/threonine-protein kinase VRK2 OS=Homo sapiens OX=9606 GN=VRK2 PE=1 SV=3"	"2"	"1"	"2"	"1"	"508"	"58.1"	"8.84"	"371.03"	"2.54"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"other membranes;mitochondrion;ER/Golgi;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"7444"	"ENSG00000028116"	"VRK2"	"B4DKL0; D6W5D4; D6W5D6; hsa:7444; Q49AK9; Q53EU9; Q53S39; Q53S77; Q53TU1; Q86Y07; Q86Y08; Q86Y09; Q86Y10; Q86Y11; Q86Y12; Q8IXI5; Q99987"	""	"RAC1 GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOD GTPase cycle"	"5"	"0"	"12.2"	"28.8"	"27.6"	"10.5"	"27.4"	"15.1"	"29.8"	"30.5"	"40.3"	"61.6"	"121.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UMY4"	"Sorting nexin-12 OS=Homo sapiens OX=9606 GN=SNX12 PE=1 SV=4"	"6"	"1"	"2"	"1"	"162"	"18.9"	"8.44"	"247.97"	"2.54"	"1"	"1"	"transport;other biological processes"	"other membranes;other cytoplasmic organelle"	"other molecular function"	"Pf00787"	"29934"	"ENSG00000147164"	"SNX12"	"F8W8K5; hsa:29934; Q8WUG9; Q9UMY4"	""	""	"0"	"0"	"33.0"	"94.2"	"94.7"	"27.2"	"70.8"	"36.7"	"65.0"	"56.9"	"85.8"	"122.4"	"168.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6NVY1"	"3-hydroxyisobutyryl-CoA hydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=HIBCH PE=1 SV=2"	"7"	"2"	"3"	"2"	"386"	"43.5"	"8.19"	"548.61"	"2.54"	"2"	"1"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf16113"	"26275"	"ENSG00000198130"	"HIBCH"	"D3DPI4; hsa:26275; Q53GA8; Q53GF2; Q53RF7; Q53TC6; Q6NVY1; Q92931; Q9BS94"	"Amino acid metabolism"	"Branched-chain amino acid catabolism"	"2"	"0"	"10.1"	"19.5"	"21.7"	"6.7"	"23.6"	"10.9"	"18.9"	"13.7"	"12.7"	"25.3"	"31.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NAN2"	"Mitoguardin 1 OS=Homo sapiens OX=9606 GN=MIGA1 PE=1 SV=1"	"3"	"1"	"1"	"1"	"632"	"71.0"	"5.63"	""	"2.54"	""	"1"	"cell organization and biogenesis"	"plasma membrane;other membranes;mitochondrion"	"other molecular function"	"Pf10265"	"374986"	"ENSG00000180488"	"MIGA1"	"hsa:374986; Q6MZG0; Q8NAN2"	""	"Synthesis of PA"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14929"	"Histone acetyltransferase type B catalytic subunit OS=Homo sapiens OX=9606 GN=HAT1 PE=1 SV=1"	"1"	"1"	"1"	"1"	"419"	"49.5"	"5.69"	""	"2.54"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf10394"	"100598934; 100970485; 102127119; 103217315; 104673520; 105548069; 105579802; 695933"	"ENSCATG00000044185; ENSCSAG00000014790; ENSMFAG00000044656; ENSMLEG00000030988; ENSMMUG00000007313; ENSNLEG00000031960; ENSPPAG00000043422; ENSPPYG00000012932; ENSPTEG00000037699; ENSPTRG00000012637; ENSRROG00000043073; ENSTGEG00000018560"	"HAT1"	"A0A0D9RQL6; A0A2I3GP06; A0A2J8PQW8; A0A2J8VQX1; A0A2K5P0H4; A0A2K5VNP4; A0A2K5YDV9; A0A2K6REU7; A0A2R9CI71; A0A663DCK2; A0A6D2WXR9; A0A8C9IWX6; A0A8D2FM88; A0A8J8XV08; A0A8J8YED4; caty:105579802; csab:103217315; F7GNR2; F7GNT9; G7N8B0; G7PKT8; H2P7T9; H2QIZ3; mcc:695933; mcf:102127119; mleu:105548069; nle:100598934; pps:100970485; rro:104673520"	""	""	"0"	"0"	"82.3"	"279.7"	"254.5"	"98.4"	"241.8"	"116.8"	"163.4"	"136.2"	"157.9"	"192.8"	"329.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95379"	"Tumor necrosis factor alpha-induced protein 8 OS=Homo sapiens OX=9606 GN=TNFAIP8 PE=1 SV=1"	"5"	"1"	"2"	"1"	"198"	"23.0"	"7.93"	"271.83"	"2.53"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"enzyme regulator activity"	"Pf05527"	"25816"	"ENSG00000145779"	"TNFAIP8"	"B3KMH1; B3KMI2; B7Z713; hsa:25816; O95379; Q9P1Q1; Q9UER5; Q9UP47"	""	"PI Metabolism"	"1"	"0"	"22.1"	"43.9"	"42.3"	"18.9"	"54.2"	"27.7"	"66.1"	"105.9"	"216.4"	"264.9"	"305.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14527"	"Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2"	"2"	"2"	"4"	"2"	"1009"	"113.9"	"8.60"	"1030.73"	"2.53"	"2"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf08797, Pf13923"	"6596"	"ENSG00000071794"	"HLTF"	"D3DNH3; hsa:6596; Q14527; Q14536; Q16051; Q7KYJ6; Q86YA5; Q92652; Q96KM9"	"Retinoblastoma gene in cancer"	"E3 ubiquitin ligases ubiquitinate target proteins"	"2"	"0"	"63.3"	"81.9"	"98.2"	"41.5"	"102.2"	"56.6"	"105.1"	"65.6"	"93.9"	"138.9"	"204.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P28482"	"Mitogen-activated protein kinase 1 OS=Homo sapiens OX=9606 GN=MAPK1 PE=1 SV=3"	"4"	"2"	"3"	"2"	"360"	"41.4"	"6.98"	"576.12"	"2.53"	"2"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00069"	"5594"	"ENSG00000100030"	"MAPK1"	"A8CZ64; hsa:5594; P28482"	"IL-5 signaling pathway; Osteopontin signaling; Physiological and pathological hypertrophy of the heart; Angiogenesis; MicroRNAs in cardiomyocyte hypertrophy; Type II diabetes mellitus; Heart development; Integrin-mediated cell adhesion; IL-1 signaling pathway; Thyroxine (thyroid hormone) production; RANKL/RANK signaling pathway; Thyroid stimulating hormone (TSH) signaling pathway; Leptin signaling pathway; Follicle stimulating hormone (FSH) signaling pathway; TNF-related weak inducer of apoptosis (TWEAK) signaling pathway; Prolactin signaling pathway; IL-7 signaling pathway; Alzheimer's disease and miRNA effects; IL-17 signaling pathway; Endothelin pathways; IL-9 signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; Glioblastoma signaling pathways; Androgen receptor network in prostate cancer; B cell receptor signaling pathway; TNF-alpha signaling pathway; AGE/RAGE pathway; Interleukin-11 signaling pathway; Corticotropin-releasing hormone signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Spinal cord injury; Alpha 6 beta 4 signaling pathway; PDGF pathway; Aryl hydrocarbon receptor pathway; S1P receptor signal transduction; Ebstein-Barr virus LMP1 signaling; Common pathways underlying drug addiction; Interleukin-1 (IL-1) structural pathway; Cardiac hypertrophic response; Bladder cancer; IL-3 signaling pathway; Apoptosis-related network due to altered Notch3 in ovarian cancer; TCA cycle nutrient use and invasiveness of ovarian cancer; Kit receptor signaling pathway; Focal adhesion; Hepatocyte growth factor receptor signaling; MFAP5-mediated ovarian cancer cell motility and invasiveness; RAC1/PAK1/p38/MMP2 pathway; Wnt signaling pathway; IL6 signaling pathway; Hypothesized pathways in pathogenesis of cardiovascular disease; BDNF-TrkB signaling; Physico-chemical features and toxicity-associated pathways; MAPK signaling pathway; MAPK and NFkB signaling pathways inhibited by Yersinia YopJ; ERK pathway in Huntington's disease; Toll-like receptor signaling related to MyD88; TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition; 4-hydroxytamoxifen, dexamethasone, and retinoic acids regulation of p27 expression; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Chemokine signaling pathway; Embryonic stem cell pluripotency pathways; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; IL-4 signaling pathway; Prion disease pathway; Endometrial cancer; PI3K-Akt signaling pathway; Chromosomal and microsatellite instability in colorectal cancer ; Ebola virus infection in host; MAPK cascade; Ras signaling; Epithelial to mesenchymal transition in colorectal cancer; Non-small cell lung cancer; Breast cancer pathway; Pancreatic adenocarcinoma pathway; Acute viral myocarditis; Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells; Neovascularisation processes; Non-genomic actions of 1,25 dihydroxyvitamin D3; EGF/EGFR signaling pathway; Bile acids synthesis and enterohepatic circulation ; Resistin as a regulator of inflammation; Relationship between inflammation, COX-2 and EGFR; Envelope proteins and their potential roles in EDMD physiopathology; Regulatory circuits of the STAT3 signaling pathway; Synaptic signaling pathways associated with autism spectrum disorder; Fragile X syndrome; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Translation inhibitors in chronically activated PDGFRA cells; Gastrin signaling pathway; Hepatitis B infection; Melanoma; Netrin-UNC5B signaling pathway; IL-18 signaling pathway; FGFR3 signaling in chondrocyte proliferation and terminal differentiation; Osteoblast differentiation and related diseases; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; Regucalcin in proximal tubule epithelial kidney cells; Kisspeptin/kisspeptin receptor system in the ovary; MAP3K1 role in promoting and blocking gonadal determination; CAMKK2 pathway; Disruption of postsynaptic signaling by CNV; Host-pathogen interaction of human coronaviruses - MAPK signaling; IL-2 signaling pathway; RAS and bradykinin pathways in COVID-19; Angiotensin II receptor type 1 pathway; Kallmann syndrome; Neuroinflammation and glutamatergic signaling; Pleural mesothelioma; Orexin receptor pathway; CCL18 signaling pathway; Regulation of actin cytoskeleton; Sphingolipid metabolism in senescence; Alzheimer's disease; Th17 cell differentiation pathway; GDNF signaling; 2q11.2 copy number variation syndrome; 2q13 copy number variation syndrome; Hippocampal synaptogenesis and neurogenesis; Comprehensive IL-17A signaling; Genetic causes of porto-sinusoidal vascular disease; Female steroid hormones in cardiomyocyte energy metabolism; Cardiomyocyte signaling pathways converging on Titin; IL-26 signaling pathways; A network map of Macrophage-stimulating protein (MSP) signaling; Role of hypoxia, angiogenesis, and FGF pathway in OA chondrocyte hypertrophy; EPO receptor signaling; ErbB signaling pathway; T-cell receptor signaling pathway; DNA damage response (only ATM dependent); Estrogen signaling pathway; Vitamin A and carotenoid metabolism; Toll-like receptor signaling pathway"	"Neutrophil degranulation; NPAS4 regulates expression of target genes; Estrogen-dependent nuclear events downstream of ESR-membrane signaling; Oxidative Stress Induced Senescence; Senescence-Associated Secretory Phenotype (SASP); Recycling pathway of L1; Downregulation of SMAD2/3:SMAD4 transcriptional activity; Regulation of HSF1-mediated heat shock response; Regulation of actin dynamics for phagocytic cup formation; FCERI mediated MAPK activation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Signaling by BRAF and RAF1 fusions; Thrombin signalling through proteinase activated receptors (PARs); SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Regulation of PTEN gene transcription; Signaling by NODAL; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Interferon gamma signaling; Oncogene Induced Senescence; Growth hormone receptor signaling; Regulation of the apoptosome activity; Signal transduction by L1; NCAM signaling for neurite out-growth; RUNX2 regulates osteoblast differentiation; RSK activation; Estrogen-stimulated signaling through PRKCZ; Spry regulation of FGF signaling; Suppression of apoptosis; MAPK1 (ERK2) activation; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; IFNG signaling activates MAPKs; Golgi Cisternae Pericentriolar Stack Reorganization; Signaling by Activin; Activation of the AP-1 family of transcription factors; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; Frs2-mediated activation; Signal attenuation; Gastrin-CREB signalling pathway via PKC and MAPK; Nuclear events stimulated by ALK signaling in cancer; ESR-mediated signaling; Negative feedback regulation of MAPK pathway; Advanced glycosylation endproduct receptor signaling; RHO GTPases Activate NADPH Oxidases; ERKs are inactivated; Signaling by MAP2K mutants; phospho-PLA2 pathway; Signaling by MAPK mutants"	"197"	"0"	"166.1"	"584.5"	"503.5"	"152.8"	"405.7"	"191.4"	"452.0"	"385.9"	"492.0"	"742.6"	"1224.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5TCZ1"	"SH3 and PX domain-containing protein 2A OS=Homo sapiens OX=9606 GN=SH3PXD2A PE=1 SV=1"	"1"	"1"	"1"	"1"	"1133"	"125.2"	"8.90"	""	"2.53"	""	"1"	"other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00018, Pf00787"	"9644"	"ENSG00000107957"	"SH3PXD2A"	"D3DR98; hsa:9644; O43302; Q5TCZ1; Q5TCZ2; Q5TDQ8"	""	"CDC42 GTPase cycle; Invadopodia formation"	"2"	"0"	"23.7"	"53.4"	"61.4"	"29.3"	"55.6"	"25.6"	"51.1"	"39.3"	"57.0"	"77.1"	"95.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BTD8"	"RNA-binding protein 42 OS=Homo sapiens OX=9606 GN=RBM42 PE=1 SV=1"	"2"	"1"	"2"	"1"	"480"	"50.4"	"9.63"	"263.17"	"2.53"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"79171"	"ENSG00000126254"	"RBM42"	"hsa:79171; O00320; Q8N5R7; Q9BTD8; Q9BU66"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15014"	"Mortality factor 4-like protein 2 OS=Homo sapiens OX=9606 GN=MORF4L2 PE=1 SV=1"	"3"	"1"	"2"	"1"	"288"	"32.3"	"9.72"	"249.44"	"2.53"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	""	"Pf05712"	"9643"	"ENSG00000123562"	"MORF4L2"	"B3KP92; D3DXA5; hsa:9643; Q15014; Q567V0; Q8J026"	""	"HATs acetylate histones"	"1"	"0"	"54.4"	"110.8"	"119.3"	"51.3"	"113.9"	"61.3"	"176.9"	"134.1"	"235.6"	"214.7"	"316.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UMX5"	"Neudesin OS=Homo sapiens OX=9606 GN=NENF PE=1 SV=1"	"6"	"1"	"2"	"1"	"172"	"18.8"	"5.69"	"294.83"	"2.53"	"1"	"1"	"signal transduction;other biological processes"	"non-structural extracellular;other membranes;mitochondrion;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00173"	"29937"	"ENSG00000117691"	"NENF"	"A1KYQ8; hsa:29937; Q53FZ6; Q5TM90; Q9UMX5"	""	""	"0"	"0"	"2.3"	"34.1"	"27.6"	"0.0"	"17.4"	"2.9"	"4.6"	"4.2"	"5.0"	"8.0"	"22.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P56537"	"Eukaryotic translation initiation factor 6 OS=Homo sapiens OX=9606 GN=EIF6 PE=1 SV=1"	"4"	"1"	"1"	"1"	"245"	"26.6"	"4.68"	""	"2.52"	""	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf01912"	"3692"	"ENSG00000242372"	"EIF6"	"B7ZBG9; hsa:3692; P56537; Q6IBN8; Q96TD5"	"Translation factors; Genetic causes of porto-sinusoidal vascular disease"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P43490"	"Nicotinamide phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=NAMPT PE=1 SV=1"	"1"	"1"	"2"	"1"	"491"	"55.5"	"7.15"	"268.99"	"2.52"	"1"	"1"	"cell-cell signaling;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf04095, Pf18127"	"10135"	"ENSG00000105835"	"NAMPT"	"A4D0Q9; A4D0R0; hsa:10135; P43490; Q3KQV0; Q8WW95"	"Adipogenesis; NAD metabolism, sirtuins and aging; NAD+ metabolism; NAD+ biosynthetic pathways; Caloric restriction and aging; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence"	"NPAS4 regulates expression of target genes; BMAL1:CLOCK,NPAS2 activates circadian gene expression; Nicotinamide salvaging"	"9"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N9I9"	"Probable E3 ubiquitin-protein ligase DTX3 OS=Homo sapiens OX=9606 GN=DTX3 PE=1 SV=2"	"3"	"1"	"1"	"1"	"347"	"38.0"	"8.73"	""	"2.52"	""	"1"	"protein metabolism;other metabolic processes;signal transduction"	"other cell component"	"other molecular function"	"Pf13923, Pf18102"	"196403"	"ENSG00000178498"	"DTX3"	"hsa:196403; Q53ZZ2; Q8N9I9; Q8NAU6; Q8NDS8"	"Notch signaling"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15234"	"Protein CASC3 OS=Homo sapiens OX=9606 GN=CASC3 PE=1 SV=2"	"2"	"1"	"2"	"1"	"703"	"76.2"	"6.48"	"270.83"	"2.52"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09405"	"22794"	"ENSG00000108349"	"CASC3"	"A8K8R0; hsa:22794; O15234"	""	"Regulation of expression of SLITs and ROBOs; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96KQ4"	"Apoptosis-stimulating of p53 protein 1 OS=Homo sapiens OX=9606 GN=PPP1R13B PE=1 SV=3"	"1"	"1"	"2"	"1"	"1090"	"119.5"	"6.76"	"296.58"	"2.52"	"1"	"1"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00018, Pf00023"	"23368"	"ENSG00000088808"	"PPP1R13B"	"B2RMX5; hsa:23368; O94870; Q96KQ4"	""	"TP53 Regulates Transcription of Death Receptors and Ligands; Activation of PUMA and translocation to mitochondria; TP53 Regulates Transcription of Genes Involved in Cytochrome C Release; TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain; Regulation of TP53 Activity through Association with Co-factors"	"5"	"0"	"11.5"	"31.0"	"34.3"	"16.9"	"29.5"	"14.9"	"46.0"	"29.2"	"36.4"	"48.7"	"56.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NUW8"	"Tyrosyl-DNA phosphodiesterase 1 OS=Homo sapiens OX=9606 GN=TDP1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"608"	"68.4"	"7.65"	"252.23"	"2.52"	"1"	"1"	"DNA metabolism;other metabolic processes;stress response"	"plasma membrane;other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06087"	"55775"	"ENSG00000042088"	"TDP1"	"hsa:55775; Q2HXX4; Q86TV8; Q96BK7; Q9NUW8; Q9NZM7; Q9NZM8"	""	"Nonhomologous End-Joining (NHEJ)"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00505"	"Importin subunit alpha-4 OS=Homo sapiens OX=9606 GN=KPNA3 PE=1 SV=2"	"2"	"1"	"2"	"1"	"521"	"57.8"	"4.94"	"244.17"	"2.51"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00514, Pf01749, Pf16186"	"3839"	"ENSG00000102753"	"KPNA3"	"hsa:3839; O00191; O00505; O43195; Q5JVM9; Q8IYQ9; Q96AA7"	""	"ISG15 antiviral mechanism; NS1 Mediated Effects on Host Pathways"	"2"	"0"	"11.7"	"27.4"	"30.6"	"9.7"	"30.8"	"13.0"	"18.6"	"13.0"	"15.5"	"34.8"	"54.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16514"	"Transcription initiation factor TFIID subunit 12 OS=Homo sapiens OX=9606 GN=TAF12 PE=1 SV=1"	"7"	"1"	"1"	"1"	"161"	"17.9"	"7.99"	""	"2.51"	""	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03847"	"6883"	"ENSG00000120656"	"TAF12"	"D3DPM5; hsa:6883; Q15775; Q16514; Q5T077"	"Eukaryotic transcription initiation"	"HATs acetylate histones; RNA Polymerase II Pre-transcription Events; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; Regulation of TP53 Activity through Phosphorylation; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation"	"11"	"0"	"3.7"	"8.2"	"11.2"	"7.9"	"9.2"	"6.0"	"12.2"	"7.7"	"9.0"	"19.7"	"19.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N9N7"	"Leucine-rich repeat-containing protein 57 OS=Homo sapiens OX=9606 GN=LRRC57 PE=1 SV=1"	"5"	"1"	"2"	"1"	"239"	"26.7"	"8.43"	"235.69"	"2.51"	"1"	"1"	""	"other membranes"	""	"Pf13855"	"255252"	"ENSG00000180979"	"LRRC57"	"hsa:255252; Q7Z2Z6; Q8N1T6; Q8N9N7"	""	""	"0"	"0"	"13.4"	"32.9"	"28.9"	"11.4"	"31.1"	"18.7"	"30.3"	"26.1"	"31.4"	"36.8"	"45.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H9T3"	"Elongator complex protein 3 OS=Homo sapiens OX=9606 GN=ELP3 PE=1 SV=2"	"2"	"1"	"2"	"1"	"547"	"62.2"	"8.88"	"270.23"	"2.51"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00583, Pf04055, Pf16199"	"55140"	"ENSG00000134014"	"ELP3"	"B4DE19; B4DIG1; E2QRI5; hsa:55140; Q53G84; Q6AWB0; Q9BVF7; Q9H9T3; Q9NVZ1"	"Ethanol effects on histone modifications"	"HATs acetylate histones"	"2"	"0"	"11.1"	"28.2"	"27.3"	"11.1"	"18.6"	"8.4"	"15.3"	"6.1"	"13.3"	"21.0"	"34.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P16383"	"GC-rich sequence DNA-binding factor 2 OS=Homo sapiens OX=9606 GN=GCFC2 PE=1 SV=2"	"1"	"1"	"2"	"1"	"781"	"89.3"	"5.99"	"302.22"	"2.50"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity"	"Pf07842"	"6936"	"ENSG00000005436"	"GCFC2"	"A4UHQ8; A4UHQ9; hsa:6936; O95032; P16383; Q53TY0; Q6P2F2"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"12.4"	"44.1"	"39.2"	"8.6"	"37.2"	"13.2"	"34.5"	"23.3"	"29.5"	"35.5"	"65.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92733"	"Proline-rich protein PRCC OS=Homo sapiens OX=9606 GN=PRCC PE=1 SV=1"	"5"	"3"	"3"	"3"	"491"	"52.4"	"5.10"	"665.16"	"2.50"	"2"	"1"	"cell cycle OR cell proliferation;other biological processes"	"nucleus"	""	"Pf10253"	"5546"	"ENSG00000143294"	"PRCC"	"A8K1F7; hsa:5546; O00665; O00724; Q5SZ06; Q92733"	"Type 2 papillary renal cell carcinoma; IL-18 signaling pathway"	"mRNA Splicing - Major Pathway"	"3"	"0"	"237.8"	"287.7"	"309.0"	"200.2"	"330.1"	"238.2"	"510.1"	"366.2"	"532.7"	"575.5"	"717.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q969T9"	"WW domain-binding protein 2 OS=Homo sapiens OX=9606 GN=WBP2 PE=1 SV=1"	"7"	"2"	"3"	"2"	"261"	"28.1"	"5.91"	"578.24"	"2.50"	"2"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02893"	"23558"	"ENSG00000132471"	"WBP2"	"B4DFG2; hsa:23558; O95638; Q969T9"	""	""	"0"	"0"	"153.0"	"183.2"	"171.9"	"95.0"	"187.7"	"126.6"	"112.8"	"87.1"	"143.2"	"153.9"	"206.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14980"	"Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2"	"1"	"1"	"1"	"1"	"2115"	"238.1"	"5.78"	""	"2.50"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	""	"4926"	"ENSG00000137497"	"NUMA1"	"H0YH75; hsa:4926; Q14980; Q14981; Q9BTE9"	"Ectoderm differentiation; Ectoderm differentiation; 8p23.1 copy number variation syndrome"	"Recruitment of NuMA to mitotic centrosomes; Mitotic Prophase"	"5"	"0"	"47.0"	"129.8"	"156.2"	"45.8"	"140.1"	"65.6"	"84.2"	"63.7"	"99.5"	"139.3"	"203.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15118"	"[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial OS=Homo sapiens OX=9606 GN=PDK1 PE=1 SV=1"	"3"	"1"	"2"	"1"	"436"	"49.2"	"8.81"	"313.19"	"2.50"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"mitochondrion"	"kinase activity;other molecular function"	"Pf02518, Pf10436"	"5163"	"ENSG00000152256"	"PDK1"	"B2R6T1; B7Z937; D3DPD8; E9PD65; hsa:5163; Q15118; Q308M4"	"T cell receptor and co-stimulatory signaling; PI3K-AKT-mTOR signaling pathway and therapeutic opportunities; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection; Non-small cell lung cancer; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Aspirin and miRNAs; PKC-gamma calcium signaling pathway in ataxia; Kisspeptin/kisspeptin receptor system in the ovary; TCA cycle in senescence; Pleural mesothelioma; Orexin receptor pathway; Resolvin E1 and resolvin D1 signaling pathways promoting inflammation resolution; Glucose metabolism in triple-negative breast cancer cells; EPO receptor signaling; DNA damage response (only ATM dependent)"	"Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid"	"19"	"0"	"34.5"	"54.6"	"48.5"	"24.6"	"49.5"	"33.2"	"72.2"	"58.4"	"82.8"	"109.0"	"162.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P1Q0"	"LETM1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=LETMD1 PE=1 SV=1"	"3"	"1"	"2"	"1"	"360"	"41.8"	"10.32"	"269.98"	"2.50"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"other membranes;mitochondrion;nucleus"	"enzyme regulator activity;translation activity;other molecular function"	"Pf07766"	"25875"	"ENSG00000050426"	"LETMD1"	"A6NER7; B3KXK7; hsa:25875; Q6P1Q0; Q6X2E4; Q6X2E5; Q7L2G9; Q7L690; Q8WXW6; Q96PK7; Q9BY59; Q9Y3X3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y6K0"	"Choline/ethanolaminephosphotransferase 1 OS=Homo sapiens OX=9606 GN=CEPT1 PE=1 SV=1"	"3"	"1"	"1"	"1"	"416"	"46.5"	"8.21"	""	"2.50"	""	"1"	"other metabolic processes"	"other membranes;ER/Golgi;nucleus"	"other molecular function"	"Pf01066"	"10390"	"ENSG00000134255"	"CEPT1"	"hsa:10390; Q69YJ9; Q9P0Y8; Q9Y6K0"	"Trans-sulfuration, one-carbon metabolism and related pathways; Kennedy pathway from sphingolipids"	"Synthesis of PC; Synthesis of PE"	"4"	"0"	"19.4"	"25.1"	"33.0"	"17.4"	"47.0"	"27.9"	"44.3"	"26.3"	"33.1"	"76.9"	"41.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75592"	"E3 ubiquitin-protein ligase MYCBP2 OS=Homo sapiens OX=9606 GN=MYCBP2 PE=1 SV=4"	"0"	"1"	"2"	"1"	"4678"	"513.3"	"7.02"	"346.51"	"2.50"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00415, Pf03256, Pf08005, Pf08239, Pf13540, Pf13639"	"23077"	"ENSG00000005810"	"MYCBP2"	"A6NJC6; hsa:23077; O75592; Q5JSX8; Q5VZN6; Q6PIB6; Q9UQ11; Q9Y6E4"	"3q29 copy number variation syndrome"	""	"1"	"0"	"11.7"	"18.9"	"19.5"	"9.4"	"17.7"	"10.0"	"7.5"	"12.5"	"11.4"	"20.2"	"35.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P42696"	"RNA-binding protein 34 OS=Homo sapiens OX=9606 GN=RBM34 PE=1 SV=2"	"5"	"1"	"1"	"1"	"430"	"48.5"	"10.11"	""	"2.49"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"23029"	"ENSG00000188739"	"RBM34"	"A8K8J7; hsa:23029; P42696; Q8N2Z8; Q9H5A1"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P17612"	"cAMP-dependent protein kinase catalytic subunit alpha OS=Homo sapiens OX=9606 GN=PRKACA PE=1 SV=2"	"3"	"1"	"2"	"1"	"351"	"40.6"	"8.79"	"310.53"	"2.49"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069"	"5566"	"ENSG00000072062; ENSG00000288516"	"PRKACA"	"hsa:5566; P17612; Q32P54; Q9H2Y0; Q9NRB4; Q9NRH9"	"Nicotine effect on dopaminergic neurons; Sterol regulatory element-binding proteins (SREBP) signaling; Follicle stimulating hormone (FSH) signaling pathway; Microtubule cytoskeleton regulation; Dopamine metabolism; Common pathways underlying drug addiction; Complement system; Mesodermal commitment pathway; IL-3 signaling pathway; Myometrial relaxation and contraction pathways; Mesodermal commitment pathway; G protein signaling pathways; MAPK signaling pathway; Cannabinoid receptor signaling; Lipid metabolism pathway; Phosphodiesterases in neuronal function; Ras signaling; Hedgehog signaling pathway; Thermogenesis; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Gastrin signaling pathway; Endochondral ossification; Endochondral ossification with skeletal dysplasias; GPR143 in melanocytes and retinal pigment epithelium cells; Neuroinflammation and glutamatergic signaling; GDNF signaling; Urotensin-II-mediated signaling pathway; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways; Estrogen signaling pathway"	"Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; MAPK6/MAPK4 signaling; Regulation of PLK1 Activity at G2/M Transition; FCGR3A-mediated IL10 synthesis; Triglyceride catabolism; Recruitment of NuMA to mitotic centrosomes; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production; Ion homeostasis; Interleukin-3, Interleukin-5 and GM-CSF signaling; RET signaling; VEGFA-VEGFR2 Pathway; Factors involved in megakaryocyte development and platelet production; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Vasopressin regulates renal water homeostasis via Aquaporins; Regulation of MECP2 expression and activity; PKA activation; PKA activation in glucagon signalling; Regulation of glycolysis by fructose 2,6-bisphosphate metabolism; CD209 (DC-SIGN) signaling; Rap1 signalling; HDL assembly; DARPP-32 events; CREB1 phosphorylation through the activation of Adenylate Cyclase; Loss of phosphorylation of MECP2 at T308; ROBO receptors bind AKAP5; PKA-mediated phosphorylation of key metabolic factors"	"70"	"0"	"90.6"	"201.5"	"202.7"	"77.7"	"178.0"	"96.3"	"199.4"	"162.9"	"205.3"	"264.5"	"405.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96DV4"	"39S ribosomal protein L38, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL38 PE=1 SV=2"	"2"	"1"	"2"	"1"	"380"	"44.6"	"7.53"	"312.50"	"2.49"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	""	"Pf01161"	"64978"	"ENSG00000204316"	"MRPL38"	"B3KN96; hsa:64978; Q96DV4; Q96Q66; Q9P0B9"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"46.5"	"164.2"	"120.3"	"28.1"	"101.1"	"39.3"	"52.9"	"41.5"	"40.6"	"80.2"	"130.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60604"	"Ubiquitin-conjugating enzyme E2 G2 OS=Homo sapiens OX=9606 GN=UBE2G2 PE=1 SV=1"	"15"	"1"	"1"	"1"	"165"	"18.6"	"4.70"	""	"2.49"	""	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"ER/Golgi;other cell component"	"other molecular function"	"Pf00179"	"7327"	"ENSG00000184787"	"UBE2G2"	"A6NMQ7; A8K3L4; D3DSL7; hsa:7327; P56554; P60604"	"Parkin-ubiquitin proteasomal system pathway; Parkinson's disease pathway"	"Antigen processing: Ubiquitination & Proteasome degradation; Synthesis of active ubiquitin: roles of E1 and E2 enzymes"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75909"	"Cyclin-K OS=Homo sapiens OX=9606 GN=CCNK PE=1 SV=2"	"3"	"1"	"2"	"1"	"580"	"64.2"	"8.41"	"310.81"	"2.49"	"1"	"1"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00134"	"8812"	"ENSG00000090061"	"CCNK"	"hsa:8812; O75909; Q59FT6; Q86U16; Q96B63; Q9NNY9"	"Male infertility"	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes"	"10"	"0"	"6.9"	"9.4"	"13.8"	"7.6"	"10.6"	"7.0"	"16.8"	"6.1"	"12.2"	"17.5"	"23.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09496"	"Clathrin light chain A OS=Homo sapiens OX=9606 GN=CLTA PE=1 SV=1"	"8"	"3"	"4"	"3"	"248"	"27.1"	"4.51"	"851.84"	"2.49"	"3"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01086"	"1211"	"ENSG00000122705"	"CLTA"	"A8K4W3; B4DIN1; F5H6N3; hsa:1211; P09496; Q2XPN5; Q53XZ1"	"Synaptic vesicle pathway; Ebola virus infection in host; Fragile X syndrome"	"MHC class II antigen presentation; Recycling pathway of L1; Lysosome Vesicle Biogenesis; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; LDL clearance; Retrograde neurotrophin signalling; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; VLDLR internalisation and degradation; Entry of Influenza Virion into Host Cell via Endocytosis; Formation of annular gap junctions"	"17"	"0"	"360.0"	"1108.0"	"1087.2"	"318.5"	"975.2"	"402.6"	"567.1"	"446.9"	"742.7"	"929.8"	"1434.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBU8"	"Mortality factor 4-like protein 1 OS=Homo sapiens OX=9606 GN=MORF4L1 PE=1 SV=2"	"3"	"1"	"2"	"1"	"362"	"41.4"	"9.28"	"247.57"	"2.49"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf05712, Pf11717"	"10933"	"ENSG00000185787"	"MORF4L1"	"B4DKN6; B7Z6R1; D3DW88; hsa:10933; O95899; Q5QTS1; Q6NVX8; Q86YT7; Q9HBP6; Q9NSW5; Q9UBU8"	"Pathways affected in adenoid cystic carcinoma"	"HATs acetylate histones"	"2"	"0"	"21.5"	"33.8"	"42.3"	"29.1"	"47.0"	"31.5"	"62.6"	"54.1"	"69.0"	"96.4"	"90.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00170"	"AH receptor-interacting protein OS=Homo sapiens OX=9606 GN=AIP PE=1 SV=2"	"5"	"1"	"2"	"1"	"330"	"37.6"	"6.29"	"257.10"	"2.49"	"1"	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13404"	"Ubiquitin-conjugating enzyme E2 variant 1 OS=Homo sapiens OX=9606 GN=UBE2V1 PE=1 SV=2"	"7"	"1"	"2"	"1"	"147"	"16.5"	"7.93"	"277.41"	"2.48"	"1"	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf00179"	"387522; 7335"	"ENSG00000244687"	"UBE2V1"	"E1P629; hsa:387522; hsa:7335; Q13403; Q13404; Q13532; Q5TGE0; Q5TGE3; Q96H34; Q9GZT0; Q9GZW1; Q9H4J3; Q9H4J4; Q9UKL1; Q9UM48; Q9UM49; Q9UM50"	"IL-1 signaling pathway; Interleukin-1 induced activation of NF-kB; MYD88 distinct input-output pathway"	"SARS-CoV-2 activates/modulates innate and adaptive immune responses; Antigen processing: Ubiquitination & Proteasome degradation; FCERI mediated NF-kB activation; Downstream TCR signaling; CLEC7A (Dectin-1) signaling; Aggrephagy; IKK complex recruitment mediated by RIP1; JNK (c-Jun kinases) phosphorylation and  activation mediated by activated human TAK1; NOD1/2 Signaling Pathway; TICAM1, RIP1-mediated IKK complex recruitment; TAK1-dependent IKK and NF-kappa-B activation  ; IRAK1 recruits IKK complex; IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation; activated TAK1 mediates p38 MAPK activation; TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling"	"19"	"0"	"25.4"	"52.8"	"60.4"	"17.2"	"65.2"	"24.4"	"55.3"	"40.6"	"50.8"	"74.6"	"88.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IVD9"	"NudC domain-containing protein 3 OS=Homo sapiens OX=9606 GN=NUDCD3 PE=1 SV=3"	"4"	"1"	"1"	"1"	"361"	"40.8"	"5.25"	""	"2.48"	""	"1"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"other molecular function"	"Pf04969, Pf14050"	"23386"	"ENSG00000015676"	"NUDCD3"	"hsa:23386; Q8IVD9; Q9BTI3; Q9H7W9; Q9UPT4"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H5Y7"	"SLIT and NTRK-like protein 6 OS=Homo sapiens OX=9606 GN=SLITRK6 PE=2 SV=3"	"2"	"1"	"1"	"1"	"841"	"95.0"	"6.52"	""	"2.47"	""	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;other cell component"	""	"Pf13855"	"84189"	"ENSG00000184564"	"SLITRK6"	"A8K9S8; hsa:84189; Q495Q0; Q6AW93; Q9H5Y7; Q9HAA8; Q9NT60"	""	"Receptor-type tyrosine-protein phosphatases"	"1"	"0"	"87.6"	"248.8"	"224.6"	"71.4"	"171.6"	"86.6"	"122.3"	"101.5"	"156.3"	"191.8"	"239.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35914"	"Hydroxymethylglutaryl-CoA lyase, mitochondrial OS=Homo sapiens OX=9606 GN=HMGCL PE=1 SV=2"	"3"	"1"	"1"	"1"	"325"	"34.3"	"8.54"	""	"2.47"	""	"1"	"cell organization and biogenesis;other metabolic processes"	"cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00682"	"3155"	"ENSG00000117305"	"HMGCL"	"B4DUP4; B7UCC6; D3Y5K7; hsa:3155; P35914; Q6IBC0; Q96FP8"	"Amino acid metabolism"	"Peroxisomal protein import; Synthesis of Ketone Bodies"	"3"	"0"	"5.3"	"18.8"	"17.9"	"11.8"	"18.4"	"8.7"	"12.2"	"8.1"	"8.9"	"11.1"	"16.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14160"	"Protein scribble homolog OS=Homo sapiens OX=9606 GN=SCRIB PE=1 SV=4"	"1"	"1"	"2"	"1"	"1630"	"174.8"	"5.07"	"356.21"	"2.47"	"1"	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"15.4"	"46.1"	"36.7"	"8.7"	"33.1"	"9.7"	"21.6"	"18.3"	"34.3"	"43.2"	"51.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5VT66"	"Mitochondrial amidoxime-reducing component 1 OS=Homo sapiens OX=9606 GN=MTARC1 PE=1 SV=1"	"2"	"1"	"2"	"1"	"337"	"37.5"	"8.88"	"252.36"	"2.46"	"1"	"1"	"other metabolic processes;stress response;other biological processes"	"other membranes;mitochondrion;other cell component"	"other molecular function"	"Pf03473, Pf03476"	"64757"	"ENSG00000186205"	"MTARC1"	"A8K447; B2D078; hsa:64757; Q5VT66; Q5VVS9; Q5VVT0; Q5VVT1; Q8N9P5; Q96FN8; Q9H6C7"	""	"Phase I - Functionalization of compounds"	"1"	"0"	"25.1"	"101.0"	"80.1"	"21.3"	"72.7"	"32.9"	"44.1"	"36.4"	"46.8"	"80.0"	"136.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BVG4"	"Protein PBDC1 OS=Homo sapiens OX=9606 GN=PBDC1 PE=1 SV=1"	"5"	"1"	"2"	"1"	"233"	"26.0"	"4.79"	"268.37"	"2.46"	"1"	"1"	""	""	""	"Pf04669"	"51260"	"ENSG00000102390"	"PBDC1"	"hsa:51260; Q9BVG4"	""	""	"0"	"0"	"2.3"	"20.3"	"20.4"	"4.6"	"16.0"	"7.1"	"11.3"	"12.4"	"19.2"	"18.9"	"28.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WUW1"	"Protein BRICK1 OS=Homo sapiens OX=9606 GN=BRK1 PE=1 SV=1"	"9"	"1"	"2"	"1"	"75"	"8.7"	"5.45"	"283.83"	"2.46"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	""	"55845"	"ENSG00000254999"	"BRK1"	"B2R5E2; hsa:55845; Q8WUW1; Q9P082"	"Regulation of actin cytoskeleton"	"RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; VEGFA-VEGFR2 Pathway"	"8"	"0"	"99.6"	"170.4"	"155.6"	"90.3"	"158.3"	"96.0"	"272.8"	"215.4"	"288.3"	"585.9"	"889.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95294"	"RasGAP-activating-like protein 1 OS=Homo sapiens OX=9606 GN=RASAL1 PE=1 SV=3"	"1"	"1"	"1"	"1"	"804"	"90.0"	"6.51"	""	"2.46"	""	"1"	"signal transduction;other biological processes"	"cytosol"	"enzyme regulator activity;other molecular function"	"Pf00168, Pf00169, Pf00616, Pf00779"	"8437"	"ENSG00000111344"	"RASAL1"	"B7ZKM4; C9JFK5; F8VQX1; hsa:8437; O95294; Q52M03; Q59H24; Q96CC7"	"Ras signaling"	"Regulation of RAS by GAPs"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75165"	"DnaJ homolog subfamily C member 13 OS=Homo sapiens OX=9606 GN=DNAJC13 PE=1 SV=5"	"1"	"1"	"2"	"1"	"2243"	"254.3"	"6.74"	"349.44"	"2.46"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	""	"Pf00226, Pf14237, Pf19432"	"23317"	"ENSG00000138246"	"DNAJC13"	"hsa:23317; O75165; Q3L0T1; Q6PI82; Q6UJ77; Q6ZSW1; Q6ZUT5; Q86XG3; Q96DC1; Q9BWK9"	""	"Neutrophil degranulation"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9C037"	"E3 ubiquitin-protein ligase TRIM4 OS=Homo sapiens OX=9606 GN=TRIM4 PE=1 SV=2"	"2"	"1"	"4"	"1"	"500"	"57.4"	"8.10"	""	"2.46"	""	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00622, Pf00643, Pf15227"	"89122"	"ENSG00000146833"	"TRIM4"	"A4D298; hsa:89122; Q75MK1; Q96F06; Q9C036; Q9C037"	""	"Antigen processing: Ubiquitination & Proteasome degradation; SARS-CoV-2 activates/modulates innate and adaptive immune responses; TRAF6 mediated NF-kB activation; NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10; Negative regulators of DDX58/IFIH1 signaling; Ovarian tumor domain proteases; TRAF3-dependent IRF activation pathway; TRAF6 mediated IRF7 activation"	"9"	"0"	"60.5"	"223.0"	"177.6"	"54.1"	"127.9"	"61.1"	"113.7"	"114.9"	"145.5"	"208.6"	"447.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P48201"	"ATP synthase F(0) complex subunit C3, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5MC3 PE=1 SV=1"	"5"	"1"	"2"	"1"	"142"	"14.7"	"9.45"	"310.53"	"2.45"	"1"	"1"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00137"	"518"	"ENSG00000154518"	"ATP5MC3"	"B2R4Z0; D3DPF0; hsa:518; P48201; Q4ZFX7"	"Electron transport chain: OXPHOS system in mitochondria; 7q11.23 copy number variation syndrome; Oxidative phosphorylation"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"5"	"0"	"52.1"	"167.3"	"185.5"	"53.1"	"148.3"	"85.4"	"268.7"	"556.7"	"661.5"	"568.8"	"981.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99829"	"Copine-1 OS=Homo sapiens OX=9606 GN=CPNE1 PE=1 SV=1"	"2"	"1"	"2"	"1"	"537"	"59.0"	"5.83"	"288.51"	"2.45"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00168, Pf07002"	"8904"	"ENSG00000214078"	"CPNE1"	"E1P5Q4; hsa:8904; Q6IBL3; Q99829; Q9H243; Q9NTZ7"	""	"Neutrophil degranulation; Glycerophospholipid biosynthesis"	"2"	"0"	"3.9"	"40.9"	"25.5"	"2.9"	"20.1"	"4.2"	"4.8"	"6.7"	"10.5"	"9.7"	"22.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60493"	"Sorting nexin-3 OS=Homo sapiens OX=9606 GN=SNX3 PE=1 SV=3"	"6"	"1"	"2"	"1"	"162"	"18.8"	"8.66"	"268.68"	"2.45"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00787"	"8724"	"ENSG00000112335"	"SNX3"	"A8K0B1; E1P5E4; E1P5E5; hsa:8724; O60493; O60718; Q4TT29; Q4TT31; Q5JXJ7; Q5JXJ8; Q96AP9; Q9C0J5; Q9NU45"	""	"Ub-specific processing proteases; WNT ligand biogenesis and trafficking"	"2"	"0"	"38.7"	"128.0"	"107.4"	"38.7"	"91.4"	"48.5"	"80.4"	"61.5"	"92.5"	"119.9"	"206.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N1B4"	"Vacuolar protein sorting-associated protein 52 homolog OS=Homo sapiens OX=9606 GN=VPS52 PE=1 SV=1"	"2"	"1"	"2"	"1"	"723"	"82.2"	"5.99"	"277.78"	"2.44"	"1"	"1"	"transport;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf04129"	"6293"	"ENSG00000206286; ENSG00000223501; ENSG00000224455; ENSG00000225590; ENSG00000228425; ENSG00000236014"	"VPS52"	"A2BF38; B0UZZ4; B4DNI9; hsa:6293; Q53GR4; Q5JPA0; Q5SQW1; Q8IUN6; Q8N1B4; Q9NPT5"	""	"Retrograde transport at the Trans-Golgi-Network"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75569"	"Interferon-inducible double-stranded RNA-dependent protein kinase activator A OS=Homo sapiens OX=9606 GN=PRKRA PE=1 SV=1"	"3"	"1"	"2"	"1"	"313"	"34.4"	"8.41"	"240.81"	"2.44"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00035"	"8575"	"ENSG00000180228"	"PRKRA"	"A8K3I6; hsa:8575; O75569; Q53G24; Q6X7T5; Q8NDK4"	"VEGFA-VEGFR2 signaling; Ebola virus infection in host"	"MicroRNA (miRNA) biogenesis; Small interfering RNA (siRNA) biogenesis"	"4"	"0"	"0.0"	"12.9"	"12.0"	"2.9"	"11.3"	"5.6"	"13.3"	"10.5"	"15.8"	"15.6"	"31.8"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75150"	"E3 ubiquitin-protein ligase BRE1B OS=Homo sapiens OX=9606 GN=RNF40 PE=1 SV=5"	"1"	"1"	"2"	"1"	"1001"	"113.6"	"6.29"	"283.90"	"2.44"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00097"	"9810"	"ENSG00000103549"	"RNF40"	"A0A024QZG0; hsa:9810; O75150; Q6AHZ6; Q6N005; Q7L3T6; Q8N615; Q96T18; Q9BSV9; Q9HC82"	"ATM signaling in development and disease"	"E3 ubiquitin ligases ubiquitinate target proteins"	"2"	"0"	"27.2"	"66.1"	"69.6"	"21.7"	"65.6"	"32.6"	"56.3"	"43.9"	"88.5"	"142.4"	"211.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BY42"	"Replication termination factor 2 OS=Homo sapiens OX=9606 GN=RTF2 PE=1 SV=3"	"3"	"1"	"2"	"1"	"306"	"33.9"	"8.59"	"257.26"	"2.44"	"1"	"1"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf04641"	"51507"	"ENSG00000022277"	"RTF2"	"E1P5Z9; hsa:51507; Q9BY42; Q9BYL7; Q9HCV9; Q9NX29; Q9NZZ8; Q9P002; Q9UHW3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NWB7"	"Intraflagellar transport protein 57 homolog OS=Homo sapiens OX=9606 GN=IFT57 PE=1 SV=1"	"3"	"1"	"2"	"1"	"429"	"49.1"	"4.98"	"250.49"	"2.44"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"cytoskeleton;ER/Golgi;other cell component"	"nucleic acid binding activity"	"Pf10498"	"55081"	"ENSG00000114446"	"IFT57"	"hsa:55081; Q96DA9; Q9NWB7"	"Ciliary landscape; Genes related to primary cilium development (based on CRISPR); Ciliopathies; Bardet-Biedl syndrome"	"Intraflagellar transport; Hedgehog 'off' state"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62875"	"DNA-directed RNA polymerases I, II, and III subunit RPABC5 OS=Homo sapiens OX=9606 GN=POLR2L PE=1 SV=1"	"13"	"1"	"1"	"1"	"67"	"7.6"	"7.77"	""	"2.44"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01194"	"5441"	"ENSG00000177700"	"POLR2L"	"hsa:5441; P52436; P62875; Q6FHX3"	"Pyrimidine metabolism; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; B-WICH complex positively regulates rRNA expression; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; mRNA Splicing - Major Pathway; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"56"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y305"	"Acyl-coenzyme A thioesterase 9, mitochondrial OS=Homo sapiens OX=9606 GN=ACOT9 PE=1 SV=2"	"2"	"1"	"1"	"1"	"439"	"49.9"	"8.60"	""	"2.44"	""	"1"	"other metabolic processes"	"mitochondrion"	"other molecular function"	""	"23597"	"ENSG00000123130"	"ACOT9"	"B3KNC9; B7ZM94; hsa:23597; Q9Y305"	"VEGFA-VEGFR2 signaling"	"Mitochondrial Fatty Acid Beta-Oxidation"	"2"	"0"	"12.9"	"27.6"	"22.5"	"10.4"	"20.8"	"12.1"	"28.0"	"21.0"	"27.3"	"34.3"	"57.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92973"	"Transportin-1 OS=Homo sapiens OX=9606 GN=TNPO1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"898"	"102.3"	"4.98"	"307.53"	"2.43"	"1"	"1"	"transport"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf03810, Pf13513"	"3842"	"ENSG00000083312"	"TNPO1"	"B4DVC6; hsa:3842; Q92957; Q92973; Q92975"	"22q11.2 copy number variation syndrome"	"Postmitotic nuclear pore complex (NPC) reformation; Intraflagellar transport; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"	"4"	"0"	"35.6"	"168.8"	"136.3"	"19.2"	"112.6"	"43.4"	"62.2"	"53.8"	"68.7"	"111.2"	"215.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P43405"	"Tyrosine-protein kinase SYK OS=Homo sapiens OX=9606 GN=SYK PE=1 SV=1"	"2"	"1"	"1"	"1"	"635"	"72.0"	"8.25"	""	"2.43"	""	"1"	"cell adhesion;cell-cell signaling;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;kinase activity;other molecular function"	"Pf00017, Pf07714"	"6850"	"ENSG00000165025"	"SYK"	"hsa:6850; P43405"	"IL-5 signaling pathway; RANKL/RANK signaling pathway; B cell receptor signaling pathway; IL-3 signaling pathway; Microglia pathogen phagocytosis pathway; Fibrin complement receptor 3 signaling pathway; PI3K-Akt signaling pathway; IL-2 signaling pathway; Extrafollicular and follicular B cell activation by SARS-CoV-2"	"Potential therapeutics for SARS; FCGR activation; FCGR3A-mediated IL10 synthesis; FCGR3A-mediated phagocytosis; Regulation of signaling by CBL; Role of LAT2/NTAL/LAB on calcium mobilization; FCERI mediated MAPK activation; FCERI mediated Ca+2 mobilization; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; GPVI-mediated activation cascade; Inactivation of CSF3 (G-CSF) signaling; Dectin-2 family; CLEC7A (Dectin-1) signaling; Regulation of actin dynamics for phagocytic cup formation; Role of phospholipids in phagocytosis; DAP12 signaling; Integrin signaling; Interleukin-2 signaling; FLT3 signaling through SRC family kinases"	"30"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q2KHT3"	"Protein CLEC16A OS=Homo sapiens OX=9606 GN=CLEC16A PE=1 SV=2"	"1"	"1"	"1"	"1"	"1053"	"117.6"	"5.86"	""	"2.43"	""	"1"	"other metabolic processes;stress response;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf09758, Pf19439"	"23274"	"ENSG00000038532"	"CLEC16A"	"hsa:23274; O15058; Q2KHT3; Q6ZTB2"	"Vitamin D receptor pathway"	""	"1"	"0"	"155.5"	"174.3"	"358.2"	"125.7"	"219.6"	"162.2"	"239.0"	"158.6"	"210.6"	"252.2"	"491.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P50402"	"Emerin OS=Homo sapiens OX=9606 GN=EMD PE=1 SV=1"	"5"	"1"	"2"	"1"	"254"	"29.0"	"5.50"	"315.99"	"2.43"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity"	"Pf03020"	"2010"	"ENSG00000102119"	"EMD"	"hsa:2010; P50402; Q6FI02"	"Arrhythmogenic right ventricular cardiomyopathy; Envelope proteins and their potential roles in EDMD physiopathology; Influence of laminopathies on Wnt signaling"	"RAC1 GTPase cycle; Initiation of Nuclear Envelope (NE) Reformation; Depolymerization of the Nuclear Lamina; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOD GTPase cycle; Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"	"12"	"0"	"14.2"	"30.0"	"38.4"	"17.6"	"37.4"	"21.2"	"24.0"	"13.3"	"26.0"	"26.0"	"37.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60306"	"RNA helicase aquarius OS=Homo sapiens OX=9606 GN=AQR PE=1 SV=4"	"1"	"1"	"1"	"1"	"1485"	"171.2"	"6.37"	""	"2.43"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf13086, Pf13087, Pf16399"	"9716"	"ENSG00000021776"	"AQR"	"A0JP17; A5YKK3; hsa:9716; O60306; Q2YDX9; Q6IRU8; Q6PIC8"	""	"mRNA Splicing - Major Pathway; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	"5"	"0"	"8.9"	"20.2"	"21.0"	"8.5"	"20.6"	"8.5"	"16.9"	"9.4"	"18.0"	"19.0"	"25.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A5PLN9"	"Trafficking protein particle complex subunit 13 OS=Homo sapiens OX=9606 GN=TRAPPC13 PE=1 SV=2"	"4"	"1"	"2"	"1"	"417"	"46.5"	"5.60"	"240.95"	"2.43"	"1"	"1"	"cell organization and biogenesis;transport"	"cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf06159"	"80006"	"ENSG00000113597"	"TRAPPC13"	"A5PLN9; hsa:80006; Q17RZ9; Q49A23; Q4JHG0; Q6MZG4; Q8TCM2; Q9H8I3"	""	"RAB GEFs exchange GTP for GDP on RABs"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P48382"	"DNA-binding protein RFX5 OS=Homo sapiens OX=9606 GN=RFX5 PE=1 SV=1"	"3"	"1"	"1"	"1"	"616"	"65.3"	"9.29"	""	"2.43"	""	"1"	"RNA metabolism OR transcription;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02257, Pf14621, Pf18326"	"5993"	"ENSG00000143390"	"RFX5"	"B7Z848; D3DV19; E9PFU4; hsa:5993; P48382; Q5VWC3"	"Prion disease pathway; IL-18 signaling pathway"	""	"2"	"0"	"20.4"	"23.6"	"30.5"	"21.5"	"36.7"	"23.0"	"37.5"	"30.1"	"39.3"	"42.9"	"48.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TED0"	"U3 small nucleolar RNA-associated protein 15 homolog OS=Homo sapiens OX=9606 GN=UTP15 PE=1 SV=3"	"3"	"1"	"2"	"1"	"518"	"58.4"	"9.11"	"255.86"	"2.43"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"ER/Golgi;nucleus;other cell component"	""	"Pf00400, Pf09384"	"84135"	"ENSG00000164338"	"UTP15"	"B4DU75; B4DXK8; hsa:84135; Q6IA60; Q8TED0; Q96E08; Q9H9F8"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9ULR3"	"Protein phosphatase 1H OS=Homo sapiens OX=9606 GN=PPM1H PE=1 SV=2"	"2"	"1"	"2"	"1"	"514"	"56.4"	"6.60"	"260.14"	"2.42"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00481"	"57460"	"ENSG00000111110"	"PPM1H"	"B1Q2A9; B2RXG4; hsa:57460; Q6PI86; Q9ULR3"	""	""	"0"	"0"	"13.4"	"38.9"	"26.3"	"13.8"	"21.7"	"11.9"	"18.0"	"21.2"	"22.5"	"19.2"	"31.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82933"	"28S ribosomal protein S9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS9 PE=1 SV=2"	"3"	"1"	"2"	"1"	"396"	"45.8"	"9.51"	"236.87"	"2.42"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf00380"	"64965"	"ENSG00000135972"	"MRPS9"	"hsa:64965; P82933; Q6PG40"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"39.4"	"95.7"	"99.2"	"40.4"	"102.5"	"56.1"	"78.1"	"50.7"	"77.4"	"101.1"	"149.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96DE0"	"U8 snoRNA-decapping enzyme OS=Homo sapiens OX=9606 GN=NUDT16 PE=1 SV=2"	"8"	"1"	"2"	"1"	"195"	"21.3"	"6.89"	"266.87"	"2.42"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00293"	"131870"	"ENSG00000198585"	"NUDT16"	"B4E3B4; E9PED4; F5GYJ1; hsa:131870; Q96DE0; Q96N82"	""	"Phosphate bond hydrolysis by NUDT proteins"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14578"	"Citron Rho-interacting kinase OS=Homo sapiens OX=9606 GN=CIT PE=1 SV=2"	"1"	"1"	"2"	"1"	"2027"	"231.3"	"6.57"	"305.01"	"2.42"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069, Pf00169, Pf00780"	"11113"	"ENSG00000122966"	"CIT"	"hsa:11113; O14578; Q2M5E1; Q6XUH8; Q86UQ9; Q9UPZ7"	"Pleural mesothelioma; G13 signaling pathway"	"RHOC GTPase cycle; RHOA GTPase cycle; RAC1 GTPase cycle; RHOB GTPase cycle; RHO GTPases activate CIT"	"7"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55957"	"BH3-interacting domain death agonist OS=Homo sapiens OX=9606 GN=BID PE=1 SV=1"	"6"	"1"	"2"	"1"	"195"	"22.0"	"5.44"	"270.11"	"2.42"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"other membranes;cytosol;mitochondrion"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf06393"	"637"	"ENSG00000015475"	"BID"	"hsa:637; P55957; Q549M7; Q71T04; Q7Z4M9; Q8IY86"	"miRNA regulation of DNA damage response; TP53 network; Alzheimer's disease and miRNA effects; TNF-alpha signaling pathway; Amyotrophic lateral sclerosis (ALS); Nanomaterial induced apoptosis; Apoptosis; Photodynamic therapy-induced HIF-1 survival signaling; Apoptosis modulation by HSP70; Regulation of apoptosis by parathyroid hormone-related protein; miRNA regulation of p53 pathway in prostate cancer; Non-small cell lung cancer; Nonalcoholic fatty liver disease; Measles virus infection; Small cell lung cancer; Hepatitis B infection; IL-18 signaling pathway; Host-pathogen interaction of human coronaviruses - apoptosis; Unfolded protein response; Complement system in neuronal development and plasticity; Network map of SARS-CoV-2 signaling pathway; Alzheimer's disease; DNA damage response"	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release; BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members; Activation, myristolyation of BID and translocation to mitochondria; Activation of BAD and translocation to mitochondria ; Activation and oligomerization of BAK protein; Activation, translocation and oligomerization of BAX"	"29"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NWH9"	"SAFB-like transcription modulator OS=Homo sapiens OX=9606 GN=SLTM PE=1 SV=2"	"1"	"1"	"2"	"1"	"1034"	"117.1"	"7.87"	"335.28"	"2.42"	"1"	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf02037"	"79811"	"ENSG00000137776"	"SLTM"	"A8K5V8; B2RTX3; hsa:79811; Q2VPK7; Q52MB3; Q658J7; Q6ZNF2; Q86TK6; Q9H7C3; Q9H8U9; Q9NWH9"	""	""	"0"	"0"	"11.3"	"22.7"	"21.3"	"12.8"	"19.7"	"12.1"	"41.9"	"31.7"	"38.7"	"40.7"	"54.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15498"	"Synaptobrevin homolog YKT6 OS=Homo sapiens OX=9606 GN=YKT6 PE=1 SV=1"	"4"	"1"	"2"	"1"	"198"	"22.4"	"6.92"	"286.70"	"2.42"	"1"	"1"	"cell organization and biogenesis;transport"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00957, Pf13774"	"10652"	"ENSG00000106636"	"YKT6"	"B4DR94; hsa:10652; O15498; Q53F01; Q6FGU9; Q6IB15"	""	"RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOG GTPase cycle; COPI-mediated anterograde transport; RAC3 GTPase cycle; Intra-Golgi traffic; COPII-mediated vesicle transport"	"8"	"0"	"98.6"	"175.9"	"204.1"	"104.5"	"169.0"	"115.4"	"151.4"	"120.8"	"175.1"	"202.3"	"284.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P09488"	"Glutathione S-transferase Mu 1 OS=Homo sapiens OX=9606 GN=GSTM1 PE=1 SV=3"	"6"	"1"	"1"	"1"	"218"	"25.7"	"6.70"	""	"2.42"	""	"1"	"other metabolic processes;stress response"	"cytosol;other cell component"	"other molecular function"	"Pf02798, Pf14497"	"2944"	"ENSG00000134184"	"GSTM1"	"hsa:2944; P09488; Q5GHG0; Q6FH88; Q8TC98; Q9UC96"	"Glutathione metabolism; Nuclear receptors meta-pathway; NRF2 pathway; Benzene metabolism; Estrogen metabolism; Aflatoxin B1 metabolism; Metapathway biotransformation Phase I and II"	"Paracetamol ADME; Glutathione conjugation; Azathioprine ADME"	"10"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P0V9"	"Septin-10 OS=Homo sapiens OX=9606 GN=SEPTIN10 PE=1 SV=2"	"2"	"1"	"1"	"1"	"454"	"52.6"	"6.80"	""	"2.41"	""	"1"	"cell cycle OR cell proliferation"	"cytoskeleton;other cell component"	"other molecular function"	"Pf00735"	"151011"	"ENSG00000186522"	"SEPTIN10"	"B3KRQ9; hsa:151011; Q86VP5; Q9HAH6; Q9P0V9"	""	""	"0"	"0"	"15.2"	"25.0"	"33.1"	"12.1"	"31.0"	"16.1"	"45.4"	"27.3"	"51.5"	"54.3"	"90.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13042"	"Cell division cycle protein 16 homolog OS=Homo sapiens OX=9606 GN=CDC16 PE=1 SV=2"	"3"	"1"	"2"	"1"	"620"	"71.6"	"5.85"	"236.38"	"2.41"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	""	"Pf12895, Pf13424"	"8881"	"ENSG00000130177"	"CDC16"	"A2A365; hsa:8881; Q13042; Q5T8C8; Q7Z651; Q96AE6; Q9Y564"	"Cell cycle"	"Assembly of the pre-replicative complex; Separation of Sister Chromatids; Antigen processing: Ubiquitination & Proteasome degradation; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; CDK-mediated phosphorylation and removal of Cdc6; Autodegradation of Cdh1 by Cdh1:APC/C; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of Cyclin B; Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase; Regulation of APC/C activators between G1/S and early anaphase; Phosphorylation of the APC/C; APC-Cdc20 mediated degradation of Nek2A; Senescence-Associated Secretory Phenotype (SASP); Transcriptional Regulation by VENTX; Aberrant regulation of mitotic exit in cancer due to RB1 defects"	"19"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96RN5"	"Mediator of RNA polymerase II transcription subunit 15 OS=Homo sapiens OX=9606 GN=MED15 PE=1 SV=2"	"2"	"1"	"2"	"1"	"788"	"86.7"	"9.42"	"254.73"	"2.41"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf09606"	"51586"	"ENSG00000099917"	"MED15"	"D3DX31; D3DX32; hsa:51586; O15413; Q6IC31; Q8NF16; Q96CT0; Q96IH7; Q96RN5; Q9P1T3"	"Sterol regulatory element-binding proteins (SREBP) signaling; SREBF and miR33 in cholesterol and lipid homeostasis; 22q11.2 copy number variation syndrome"	"PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; Generic Transcription Pathway"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q8NEZ5"	"F-box only protein 22 OS=Homo sapiens OX=9606 GN=FBXO22 PE=1 SV=1"	"2"	"1"	"1"	"1"	"403"	"44.5"	"7.03"	""	"2.40"	""	"1"	"protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"cytosol;cytoskeleton;nucleus"	"other molecular function"	"Pf00646, Pf10442"	"26263"	"ENSG00000167196"	"FBXO22"	"hsa:26263; Q0D2P8; Q6PIL5; Q8IXW3; Q8NEZ5; Q9H824; Q9UKC0"	""	"Antigen processing: Ubiquitination & Proteasome degradation; Neddylation"	"2"	"0"	"8.8"	"75.3"	"59.9"	"10.2"	"44.3"	"11.6"	"21.6"	"22.7"	"36.3"	"61.1"	"99.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P20248"	"Cyclin-A2 OS=Homo sapiens OX=9606 GN=CCNA2 PE=1 SV=2"	"2"	"1"	"2"	"1"	"432"	"48.5"	"6.54"	"318.50"	"2.40"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00134, Pf02984, Pf16500"	"890"	"ENSG00000145386"	"CCNA2"	"A8K7B6; hsa:890; P20248; Q2M3U6; Q4W5P4; Q6LER8"	"AMP-activated protein kinase signaling; Cell cycle; Retinoblastoma gene in cancer; IL-18 signaling pathway"	"TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; Regulation of TP53 Degradation; SCF(Skp2)-mediated degradation of p27/p21; Regulation of TP53 Activity through Phosphorylation; G2 Phase; Telomere Extension By Telomerase; Regulation of APC/C activators between G1/S and early anaphase; Senescence-Associated Secretory Phenotype (SASP); Processing of DNA double-strand break ends; DNA Damage/Telomere Stress Induced Senescence; p53-Dependent G1 DNA Damage Response; Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1; Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes"	"24"	"0"	"31.1"	"47.4"	"43.2"	"20.0"	"39.8"	"24.3"	"99.4"	"98.9"	"114.1"	"131.3"	"217.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BRJ2"	"39S ribosomal protein L45, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL45 PE=1 SV=2"	"3"	"1"	"1"	"1"	"306"	"35.3"	"9.03"	""	"2.40"	""	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	""	"Pf04280"	""	"ENSG00000277936"	"MRPL45"	"A1L436; Q6ZMJ5; Q9BRJ2"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WVT3"	"Trafficking protein particle complex subunit 12 OS=Homo sapiens OX=9606 GN=TRAPPC12 PE=1 SV=3"	"1"	"1"	"2"	"1"	"735"	"79.3"	"4.91"	"251.78"	"2.40"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	""	"Pf14559"	"51112"	"ENSG00000171853"	"TRAPPC12"	"B3KV01; D6W4Y2; hsa:51112; Q8WVT3; Q8WVW1; Q9Y395"	""	"RAB GEFs exchange GTP for GDP on RABs"	"1"	"0"	"16.9"	"21.2"	"26.5"	"6.5"	"22.3"	"9.6"	"31.7"	"26.9"	"42.2"	"55.8"	"100.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49137"	"MAP kinase-activated protein kinase 2 OS=Homo sapiens OX=9606 GN=MAPKAPK2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"400"	"45.5"	"8.68"	"338.79"	"2.40"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"9261"	"ENSG00000162889"	"MAPKAPK2"	"hsa:9261; P49137; Q5SY30; Q5SY41; Q8IYD6"	"IL-1 signaling pathway; Microtubule cytoskeleton regulation; Interleukin-1 (IL-1) structural pathway; Fas ligand pathway and stress induction of heat shock proteins; MAPK signaling pathway; VEGFA-VEGFR2 signaling; p38 MAPK signaling pathway; Pleural mesothelioma; Serotonin HTR1 group and FOS pathway; Serotonin receptor 2 and ELK-SRF/GATA4 signaling; Serotonin receptor 4/6/7 and NR3C signaling"	"Oxidative Stress Induced Senescence; Regulation of TNFR1 signaling; activated TAK1 mediates p38 MAPK activation; VEGFA-VEGFR2 Pathway; Regulation of HSF1-mediated heat shock response; p38MAPK events; CREB phosphorylation; Synthesis of Leukotrienes (LT) and Eoxins (EX); Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"	"21"	"0"	"55.6"	"142.6"	"138.1"	"44.4"	"125.4"	"72.5"	"106.5"	"77.4"	"114.5"	"141.5"	"209.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q969E8"	"Pre-rRNA-processing protein TSR2 homolog OS=Homo sapiens OX=9606 GN=TSR2 PE=1 SV=1"	"4"	"1"	"2"	"1"	"191"	"20.9"	"4.39"	"288.17"	"2.40"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf10273"	"90121"	"ENSG00000158526"	"TSR2"	"hsa:90121; Q969E8"	""	""	"0"	"0"	"53.2"	"196.1"	"189.1"	"39.3"	"159.0"	"86.7"	"104.8"	"75.9"	"99.9"	"110.3"	"220.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P0DN79"	"Cystathionine beta-synthase-like protein OS=Homo sapiens OX=9606 GN=CBSL PE=1 SV=1"	"5"	"2"	"2"	"2"	"551"	"60.5"	"6.65"	"493.30"	"2.40"	"1"	"1"	"DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00291, Pf00571"	"102724560; 875"	"ENSG00000160200"	"CBS"	"B2R993; D3DSK4; hsa:102724560; hsa:875; P35520; Q99425; Q9BWC5"	"Selenium micronutrient network; Vitamin B12 metabolism; Folate-alcohol and cancer pathway hypotheses; Folate metabolism; Trans-sulfuration pathway; Trans-sulfuration, one-carbon metabolism and related pathways; Vitamin D receptor pathway; Amino acid metabolism; Methionine metabolism leading to sulfur amino acids and related disorders; Ferroptosis; Ciliary landscape"	"Metabolism of ingested SeMet, Sec, MeSec into H2Se; Cysteine formation from homocysteine"	"13"	"0"	"64.7"	"226.3"	"191.6"	"55.3"	"187.9"	"79.4"	"108.8"	"100.6"	"133.2"	"190.5"	"280.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TDN6"	"Ribosome biogenesis protein BRX1 homolog OS=Homo sapiens OX=9606 GN=BRIX1 PE=1 SV=2"	"4"	"1"	"2"	"1"	"353"	"41.4"	"9.92"	"363.27"	"2.40"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf04427"	"55299"	"ENSG00000113460"	"BRIX1"	"A8K0P5; hsa:55299; Q3ZTT4; Q8N453; Q8TDN6; Q96DH1"	"Gastric cancer network 2"	""	"1"	"0"	"12.6"	"25.4"	"24.3"	"11.1"	"19.4"	"14.9"	"19.7"	"17.4"	"20.4"	"26.9"	"43.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P18031"	"Tyrosine-protein phosphatase non-receptor type 1 OS=Homo sapiens OX=9606 GN=PTPN1 PE=1 SV=1"	"3"	"1"	"1"	"1"	"435"	"49.9"	"6.27"	""	"2.39"	""	"1"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"other membranes;cytosol;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00102"	"5770"	"ENSG00000196396"	"PTPN1"	"hsa:5770; P18031; Q5TGD8; Q9BQV9; Q9NQQ4"	"Leptin signaling pathway; Prolactin signaling pathway; Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4); VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Insulin signaling"	"Growth hormone receptor signaling; Regulation of IFNG signaling; Regulation of IFNA/IFNB signaling; Negative regulation of MET activity; Insulin receptor recycling; Integrin signaling; MECP2 regulates neuronal receptors and channels; PTK6 Down-Regulation"	"14"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61599"	"N-alpha-acetyltransferase 20 OS=Homo sapiens OX=9606 GN=NAA20 PE=1 SV=1"	"8"	"1"	"2"	"1"	"178"	"20.4"	"5.03"	"282.48"	"2.39"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00583"	"51126"	"ENSG00000173418"	"NAA20"	"A6NHA3; B2R4G4; hsa:51126; P61599; Q5TFT7; Q9D7H8; Q9H0Y4; Q9NQH6; Q9Y6D2"	"Metapathway biotransformation Phase I and II"	""	"1"	"0"	"14.0"	"40.9"	"42.7"	"19.3"	"37.0"	"17.5"	"28.6"	"21.6"	"27.1"	"52.1"	"106.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z4V5"	"Hepatoma-derived growth factor-related protein 2 OS=Homo sapiens OX=9606 GN=HDGFL2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"671"	"74.3"	"7.49"	"279.98"	"2.39"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00855, Pf11467"	"84717"	"ENSG00000167674"	"HDGFL2"	"hsa:84717; I3L080; K7EQZ6; Q7Z4V5; Q96GI5; Q9BW08"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60981"	"Destrin OS=Homo sapiens OX=9606 GN=DSTN PE=1 SV=3"	"15"	"3"	"5"	"2"	"165"	"18.5"	"7.85"	"1124.15"	"2.39"	"3"	"1"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf00241"	"11034"	"ENSG00000125868"	"DSTN"	"B2R6N2; B4DYA6; hsa:11034; P18282; P60981; Q5W166; Q6IAW2"	"Androgen receptor signaling pathway"	""	"1"	"0"	"67.1"	"453.7"	"348.4"	"43.5"	"294.5"	"92.7"	"139.6"	"98.2"	"156.1"	"232.6"	"504.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P28838"	"Cytosol aminopeptidase OS=Homo sapiens OX=9606 GN=LAP3 PE=1 SV=3"	"2"	"1"	"2"	"1"	"519"	"56.1"	"7.93"	"283.93"	"2.39"	"1"	"1"	"protein metabolism"	"other cell component"	"other molecular function"	"Pf00883, Pf02789"	"51056"	"ENSG00000002549"	"LAP3"	"B3KMQ3; hsa:51056; P28838; Q6IAM6; Q6P0L6; Q9UQE3"	""	""	"0"	"0"	"193.7"	"638.4"	"554.7"	"136.0"	"557.7"	"199.1"	"265.4"	"169.9"	"240.2"	"233.9"	"473.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95759"	"TBC1 domain family member 8 OS=Homo sapiens OX=9606 GN=TBC1D8 PE=1 SV=3"	"1"	"1"	"1"	"1"	"1140"	"130.8"	"5.52"	""	"2.39"	""	"1"	"other biological processes"	"other membranes"	"enzyme regulator activity"	"Pf00566, Pf02893"	"11138"	"ENSG00000204634"	"TBC1D8"	"A6NDL4; A8K9W1; B9A6K4; hsa:11138; O95759; Q53SQ4; Q9UQ32"	""	""	"0"	"0"	"3.5"	"11.2"	"9.8"	"3.4"	"11.1"	"5.6"	"26.2"	"73.7"	"312.2"	"543.5"	"997.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96EY4"	"Translation machinery-associated protein 16 OS=Homo sapiens OX=9606 GN=TMA16 PE=1 SV=2"	"6"	"1"	"1"	"1"	"203"	"23.8"	"9.26"	""	"2.39"	""	"1"	"other biological processes"	"nucleus"	"other molecular function"	"Pf11176"	"55319"	"ENSG00000198498"	"TMA16"	"hsa:55319; Q0P6E4; Q0P6J1; Q96EY4; Q9NUR7"	""	""	"0"	"0"	"10.3"	"15.7"	"14.5"	"5.0"	"15.7"	"9.6"	"15.6"	"14.9"	"18.9"	"31.9"	"42.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WV22"	"Non-structural maintenance of chromosomes element 1 homolog OS=Homo sapiens OX=9606 GN=NSMCE1 PE=1 SV=5"	"2"	"1"	"1"	"1"	"266"	"30.8"	"7.47"	""	"2.38"	""	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf07574, Pf08746"	"197370"	"ENSG00000169189"	"NSMCE1"	"D3DWF6; hsa:197370; Q8WV22; Q9P045; Q9P049"	""	"SUMOylation of DNA damage response and repair proteins"	"1"	"0"	"87.1"	"129.9"	"142.0"	"67.1"	"139.2"	"98.2"	"244.1"	"182.3"	"371.7"	"557.4"	"778.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60739"	"Eukaryotic translation initiation factor 1b OS=Homo sapiens OX=9606 GN=EIF1B PE=1 SV=2"	"12"	"1"	"2"	"1"	"113"	"12.8"	"7.37"	"286.58"	"2.38"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"translational apparatus"	"translation activity;nucleic acid binding activity"	"Pf01253"	"10289"	"ENSG00000114784"	"EIF1B"	"hsa:10289; O60739; Q9UQF8"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86WR0"	"Coiled-coil domain-containing protein 25 OS=Homo sapiens OX=9606 GN=CCDC25 PE=1 SV=2"	"5"	"1"	"2"	"1"	"208"	"24.5"	"6.80"	"276.75"	"2.38"	"1"	"1"	"other biological processes"	"plasma membrane;other membranes;other cell component"	"nucleic acid binding activity"	"Pf05670"	"55246"	"ENSG00000147419"	"CCDC25"	"hsa:55246; Q0P663; Q86WR0; Q96SI2; Q9NV98"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q3KQU3"	"MAP7 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=MAP7D1 PE=1 SV=1"	"1"	"1"	"1"	"1"	"841"	"92.8"	"10.11"	""	"2.38"	""	"1"	"cell organization and biogenesis"	"cytoskeleton;other cell component"	""	"Pf05672"	"55700"	"ENSG00000116871"	"MAP7D1"	"D3DPS4; hsa:55700; Q3KQU3; Q7L8J5; Q8N905; Q8TAK0; Q9HBQ2; Q9NW29; Q9ULN3"	""	""	"0"	"0"	"5.1"	"11.4"	"12.9"	"6.2"	"9.0"	"5.8"	"12.0"	"12.9"	"13.9"	"12.6"	"14.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WXI9"	"Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1"	"2"	"1"	"1"	"1"	"593"	"65.2"	"9.70"	""	"2.38"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00320, Pf16563"	"57459"	"ENSG00000143614; ENSG00000261992"	"GATAD2B"	"D3DUZ2; hsa:57459; Q5VUR2; Q7LG68; Q8WXI9; Q9ULS0"	""	"Potential therapeutics for SARS; Regulation of PTEN gene transcription; HDACs deacetylate histones; RNA Polymerase I Transcription Initiation; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of TP53 Activity through Acetylation"	"6"	"0"	"11.7"	"26.4"	"31.0"	"17.3"	"29.8"	"19.8"	"39.6"	"27.6"	"45.8"	"64.4"	"98.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61927"	"60S ribosomal protein L37 OS=Homo sapiens OX=9606 GN=RPL37 PE=1 SV=2"	"29"	"4"	"6"	"4"	"97"	"11.1"	"11.74"	"1086.03"	"2.37"	"4"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf01907"	"6167"	"ENSG00000145592"	"RPL37"	"B2R4H2; hsa:6167; P02403; P61927; Q6IBB4; Q99883"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis"	"14"	"0"	"701.0"	"1193.7"	"1266.9"	"523.0"	"1217.3"	"664.9"	"2762.2"	"2120.1"	"2468.3"	"3068.6"	"4267.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y294"	"Histone chaperone ASF1A OS=Homo sapiens OX=9606 GN=ASF1A PE=1 SV=1"	"4"	"1"	"1"	"1"	"204"	"23.0"	"4.41"	""	"2.37"	""	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf04729"	"25842"	"ENSG00000111875"	"ASF1A"	"hsa:25842; Q6IA08; Q9P014; Q9Y294"	"22q11.2 copy number variation syndrome"	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"	"2"	"0"	"63.8"	"131.5"	"154.8"	"64.9"	"165.5"	"87.3"	"117.0"	"76.2"	"123.5"	"129.1"	"166.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P289"	"Serine/threonine-protein kinase 26 OS=Homo sapiens OX=9606 GN=STK26 PE=1 SV=2"	"4"	"2"	"3"	"2"	"416"	"46.5"	"5.29"	"518.61"	"2.37"	"2"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"51765"	"ENSG00000134602"	"STK26"	"B2RAU2; hsa:51765; Q3ZB77; Q8NC04; Q9BXC3; Q9BXC4; Q9P289"	""	"Apoptotic cleavage of cellular proteins"	"1"	"0"	"114.6"	"361.2"	"296.6"	"77.0"	"234.0"	"117.6"	"217.2"	"165.9"	"257.5"	"323.1"	"568.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75955"	"Flotillin-1 OS=Homo sapiens OX=9606 GN=FLOT1 PE=1 SV=3"	"4"	"1"	"2"	"1"	"427"	"47.3"	"7.49"	"304.40"	"2.37"	"1"	"1"	"cell organization and biogenesis;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01145"	"10211"	"ENSG00000137312; ENSG00000206379; ENSG00000206480; ENSG00000230143; ENSG00000232280"	"FLOT1"	"B4DVY7; hsa:10211; O75955; Q969J8; Q9UHW1; Q9UNV8"	"Angiopoietin-like protein 8 regulatory pathway; Insulin signaling"	"RHOC GTPase cycle; RHOA GTPase cycle; RHOB GTPase cycle; Regulation of necroptotic cell death; Synaptic adhesion-like molecules"	"8"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96RP9"	"Elongation factor G, mitochondrial OS=Homo sapiens OX=9606 GN=GFM1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"751"	"83.4"	"7.01"	"237.09"	"2.37"	"1"	"1"	"protein metabolism;other metabolic processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf00679, Pf03144, Pf03764, Pf14492"	"85476"	"ENSG00000168827"	"GFM1"	"A6NCI9; B2RCB9; B3KRW1; hsa:85476; Q6GTN2; Q96RP9; Q96T39"	""	"Mitochondrial translation elongation"	"1"	"0"	"7.3"	"46.8"	"31.8"	"9.7"	"32.4"	"13.3"	"20.7"	"16.7"	"20.3"	"30.4"	"60.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96D71"	"RalBP1-associated Eps domain-containing protein 1 OS=Homo sapiens OX=9606 GN=REPS1 PE=1 SV=3"	"1"	"1"	"2"	"1"	"796"	"86.6"	"5.69"	"307.43"	"2.36"	"1"	"1"	"transport"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf12763"	"85021"	"ENSG00000135597"	"REPS1"	"B7ZBZ8; B7ZBZ9; B7ZC00; hsa:85021; J3KP76; Q5JWJ5; Q5JWJ6; Q5JWJ7; Q8NDR7; Q8WU62; Q96D71; Q9BXY9"	""	"Cargo recognition for clathrin-mediated endocytosis"	"2"	"0"	"7.2"	"19.5"	"27.1"	"7.8"	"39.7"	"8.8"	"22.0"	"11.7"	"15.7"	"14.4"	"21.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43617"	"Trafficking protein particle complex subunit 3 OS=Homo sapiens OX=9606 GN=TRAPPC3 PE=1 SV=1"	"4"	"1"	"2"	"1"	"180"	"20.3"	"4.96"	"280.72"	"2.36"	"1"	"1"	"cell organization and biogenesis;transport"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf04051"	"27095"	"ENSG00000054116"	"TRAPPC3"	"A6NDN0; B2RDN2; D3DPS2; hsa:27095; O43617"	""	"COPII-mediated vesicle transport; RAB GEFs exchange GTP for GDP on RABs"	"2"	"0"	"28.0"	"74.5"	"60.4"	"28.5"	"48.9"	"26.1"	"64.9"	"56.8"	"72.5"	"147.2"	"229.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43252"	"Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 OS=Homo sapiens OX=9606 GN=PAPSS1 PE=1 SV=2"	"2"	"1"	"1"	"1"	"624"	"70.8"	"6.86"	""	"2.36"	""	"1"	"other metabolic processes;developmental processes"	"cytosol"	"kinase activity;other molecular function"	"Pf01583, Pf01747, Pf14306"	"9061"	"ENSG00000138801"	"PAPSS1"	"hsa:9061; O43252; O43841; O75332; Q6IAX6; Q96FB1; Q96TF4; Q9P1P9; Q9UE98"	"Sulfation biotransformation reaction"	"Signaling by BRAF and RAF1 fusions; Transport and synthesis of PAPS; Metabolism of ingested H2SeO4 and H2SeO3 into H2Se"	"4"	"0"	"10.1"	"26.9"	"28.3"	"5.8"	"23.4"	"14.0"	"26.2"	"17.3"	"27.0"	"45.8"	"59.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62328"	"Thymosin beta-4 OS=Homo sapiens OX=9606 GN=TMSB4X PE=1 SV=2"	"16"	"1"	"2"	"1"	"44"	"5.1"	"5.06"	"313.11"	"2.36"	"1"	"1"	"cell organization and biogenesis;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01290"	"7114"	"ENSG00000205542"	"TMSB4X"	"hsa:7114; P01253; P01254; P62328; Q546P5; Q63576; Q9UE55"	"Genes targeted by miRNAs in adipocytes; VEGFA-VEGFR2 signaling; IL-18 signaling pathway; Regulation of actin cytoskeleton"	"Platelet degranulation"	"5"	"0"	"52.8"	"620.9"	"571.6"	"15.7"	"464.0"	"115.5"	"174.0"	"102.4"	"151.0"	"164.2"	"450.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14735"	"Insulin-degrading enzyme OS=Homo sapiens OX=9606 GN=IDE PE=1 SV=4"	"2"	"2"	"3"	"2"	"1019"	"117.9"	"6.61"	"235.45"	"2.36"	"1"	"2"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00675, Pf05193, Pf16187"	"3416"	"ENSG00000119912"	"IDE"	"B2R721; B7ZAU2; D3DR35; hsa:3416; P14735; Q5T5N2"	"Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Ub-specific processing proteases; Peroxisomal protein import; Insulin receptor recycling"	"5"	"0"	"130.2"	"249.7"	"242.6"	"99.5"	"231.8"	"128.4"	"165.9"	"126.2"	"187.4"	"206.0"	"354.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4X0"	"AMME syndrome candidate gene 1 protein OS=Homo sapiens OX=9606 GN=AMMECR1 PE=1 SV=1"	"4"	"1"	"2"	"1"	"333"	"35.4"	"8.63"	"279.56"	"2.35"	"1"	"1"	""	"mitochondrion;nucleus"	""	"Pf01871"	"9949"	"ENSG00000101935"	"AMMECR1"	"hsa:9949; Q5JYV9; Q6P9D8; Q8WX22; Q9UIQ8; Q9Y4X0"	""	""	"0"	"0"	"3.9"	"10.4"	"10.6"	"3.2"	"8.0"	"5.0"	"10.9"	"11.5"	"28.1"	"19.8"	"19.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y696"	"Chloride intracellular channel protein 4 OS=Homo sapiens OX=9606 GN=CLIC4 PE=1 SV=4"	"7"	"1"	"1"	"1"	"253"	"28.8"	"5.59"	""	"2.35"	""	"1"	"transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"transporter activity"	"Pf13410"	"25932"	"ENSG00000169504"	"CLIC4"	"hsa:25932; Q9UFW9; Q9UQJ6; Q9Y696"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BX68"	"Histidine triad nucleotide-binding protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=HINT2 PE=1 SV=1"	"9"	"1"	"2"	"1"	"163"	"17.2"	"9.16"	"337.54"	"2.35"	"1"	"1"	"other metabolic processes;other biological processes"	"other membranes;mitochondrion;other cell component"	"other molecular function"	"Pf01230"	"84681"	"ENSG00000137133"	"HINT2"	"hsa:84681; Q5TCW3; Q9BX68"	""	"RHOD GTPase cycle"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96T58"	"Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1"	"0"	"2"	"2"	"1"	"3664"	"402.0"	"7.64"	"253.44"	"2.35"	"1"	"1"	"RNA metabolism OR transcription;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf07744"	"23013"	"ENSG00000065526"	"SPEN"	"hsa:23013; Q96T58; Q9H9A8; Q9NWH5; Q9UQ01; Q9Y556"	"Notch signaling pathway"	"RHOBTB1 GTPase cycle"	"2"	"0"	"5.8"	"16.0"	"11.9"	"7.2"	"12.6"	"5.6"	"13.4"	"13.5"	"15.6"	"18.3"	"30.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WW12"	"PEST proteolytic signal-containing nuclear protein OS=Homo sapiens OX=9606 GN=PCNP PE=1 SV=2"	"10"	"2"	"3"	"2"	"178"	"18.9"	"7.49"	"591.46"	"2.34"	"2"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes"	"nucleus"	""	"Pf15473"	"57092"	"ENSG00000081154"	"PCNP"	"B2RBE7; D3DN52; hsa:57092; Q53GF3; Q6AI44; Q8WW12; Q96CU3; Q9NS81"	""	""	"0"	"0"	"177.9"	"573.7"	"563.7"	"90.7"	"480.9"	"189.4"	"290.1"	"166.4"	"264.1"	"289.1"	"506.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00330"	"Pyruvate dehydrogenase protein X component, mitochondrial OS=Homo sapiens OX=9606 GN=PDHX PE=1 SV=3"	"1"	"1"	"2"	"1"	"501"	"54.1"	"8.66"	"286.43"	"2.34"	"1"	"1"	"other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf00198, Pf00364, Pf02817"	"8050"	"ENSG00000110435"	"PDHX"	"B4DW62; D3DR11; E9PB14; E9PBP7; hsa:8050; O00330; O60221; Q96FV8; Q99783"	"Amino acid metabolism"	"Glyoxylate metabolism and glycine degradation; Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid"	"5"	"0"	"111.2"	"256.0"	"264.5"	"114.0"	"212.8"	"183.6"	"76.2"	"57.7"	"93.9"	"122.0"	"213.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P40938"	"Replication factor C subunit 3 OS=Homo sapiens OX=9606 GN=RFC3 PE=1 SV=2"	"3"	"1"	"2"	"1"	"356"	"40.5"	"8.34"	"251.98"	"2.34"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13177"	"5983"	"ENSG00000133119"	"RFC3"	"C9JU95; hsa:5983; O15252; P40938; Q5W0E8"	"Gastric cancer network 2; Retinoblastoma gene in cancer; DNA replication; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"PCNA-Dependent Long Patch Base Excision Repair; Regulation of TP53 Activity through Phosphorylation; Activation of ATR in response to replication stress; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; Recognition of DNA damage by PCNA-containing replication complex; Dual Incision in GG-NER; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER; Polymerase switching on the C-strand of the telomere; Polymerase switching"	"28"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y6D9"	"Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2"	"1"	"1"	"1"	"1"	"718"	"83.0"	"5.92"	""	"2.34"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf05557"	"8379"	"ENSG00000002822"	"MAD1L1"	"B3KR41; hsa:8379; Q13312; Q75MI0; Q86UM4; Q9UNH0; Q9Y6D9"	"Cell cycle; Regulation of sister chromatid separation at the metaphase-anaphase transition; Pleural mesothelioma; CCL18 signaling pathway"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"10"	"0"	"51.1"	"162.3"	"217.3"	"50.5"	"152.6"	"56.0"	"160.0"	"138.0"	"192.5"	"265.0"	"381.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60884"	"DnaJ homolog subfamily A member 2 OS=Homo sapiens OX=9606 GN=DNAJA2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"412"	"45.7"	"6.48"	"250.76"	"2.34"	"1"	"1"	"stress response;other biological processes"	"other membranes;cytosol;other cell component"	"other molecular function"	"Pf00226, Pf00684, Pf01556"	"10294"	"ENSG00000069345"	"DNAJA2"	"B2R7L7; hsa:10294; O14711; O60884"	""	"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand"	"1"	"0"	"69.3"	"178.2"	"158.8"	"62.6"	"144.3"	"81.0"	"115.7"	"101.5"	"140.5"	"177.6"	"294.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q969I3"	"Glycine N-acyltransferase-like protein 1 OS=Homo sapiens OX=9606 GN=GLYATL1 PE=1 SV=1"	"2"	"1"	"1"	"1"	"302"	"35.1"	"6.87"	""	"2.33"	""	"1"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf06021, Pf08444"	"92292"	"ENSG00000166840"	"GLYATL1"	"A6NDT0; hsa:92292; Q7Z510; Q8NAW8; Q969I3"	"Amino acid conjugation of benzoic acid; Metapathway biotransformation Phase I and II"	"Aspirin ADME; Conjugation of salicylate with glycine; Conjugation of benzoate with glycine"	"5"	"0"	"61.7"	"142.7"	"131.2"	"69.2"	"114.0"	"70.2"	"146.6"	"113.9"	"165.2"	"217.4"	"372.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60733"	"85/88 kDa calcium-independent phospholipase A2 OS=Homo sapiens OX=9606 GN=PLA2G6 PE=1 SV=2"	"1"	"1"	"1"	"1"	"806"	"89.8"	"7.27"	""	"2.33"	""	"1"	"other metabolic processes;stress response;transport;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;other cell component"	"other molecular function"	"Pf00023, Pf01734"	"8398"	"ENSG00000184381"	"PLA2G6"	"A8K597; B0QYE8; hsa:8398; O60733; O75645; Q8N452; Q9UG29; Q9UIT0; Q9Y671"	"Spinal cord injury; Ras signaling; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Eicosanoid metabolism via cyclooxygenases (COX); Omega-3 / omega-6 fatty acid synthesis; Lipid metabolism in senescent cells"	"Role of phospholipids in phagocytosis; COPI-independent Golgi-to-ER retrograde traffic; Acyl chain remodelling of PC; Acyl chain remodelling of PE; Acyl chain remodeling of CL"	"11"	"0"	"123.4"	"268.0"	"309.6"	"136.9"	"280.8"	"151.6"	"202.9"	"148.8"	"191.8"	"283.7"	"715.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13619"	"Cullin-4A OS=Homo sapiens OX=9606 GN=CUL4A PE=1 SV=3"	"1"	"1"	"2"	"1"	"759"	"87.6"	"8.13"	"315.04"	"2.33"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00888, Pf10557"	"8451"	"ENSG00000139842"	"CUL4A"	"A2A2W2; hsa:8451; O75834; Q13619; Q589T6; Q5TC62; Q6UP08; Q9UP17"	"Hippo-Merlin signaling dysregulation; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"Neddylation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; DNA Damage Recognition in GG-NER; Dual Incision in GG-NER"	"13"	"0"	"13.8"	"38.7"	"33.4"	"16.7"	"41.0"	"15.5"	"33.5"	"23.5"	"35.3"	"40.6"	"77.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HC84"	"Mucin-5B OS=Homo sapiens OX=9606 GN=MUC5B PE=1 SV=3"	"0"	"1"	"2"	"1"	"5762"	"596.0"	"6.64"	"244.12"	"2.32"	"1"	"1"	""	"extracellular matrix;plasma membrane;other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf00094, Pf01826, Pf08742, Pf13330"	"727897"	"ENSG00000117983"	"MUC5B"	"hsa:727897; O00447; O00573; O14985; O15494; O95291; O95451; Q14881; Q7M4S5; Q99552; Q9HC84; Q9UE28"	"Lung fibrosis"	"Dectin-2 family; Termination of O-glycan biosynthesis; Defective GALNT3 causes HFTC; Defective C1GALT1C1 causes TNPS; Defective GALNT12 causes CRCS1"	"7"	"0"	"38.2"	"50.1"	"61.2"	"27.7"	"49.8"	"26.8"	"49.1"	"43.3"	"66.5"	"99.8"	"123.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NG48"	"Protein Lines homolog 1 OS=Homo sapiens OX=9606 GN=LINS1 PE=1 SV=2"	"1"	"1"	"1"	"1"	"757"	"85.8"	"6.52"	""	"2.32"	""	"1"	"other biological processes"	""	""	"Pf14694, Pf14695"	"55180"	"ENSG00000140471"	"LINS1"	"hsa:55180; Q8NG48; Q96FW2; Q9NVQ3"	""	""	"0"	"0"	"50.9"	"141.0"	"124.2"	"60.5"	"119.8"	"53.5"	"129.7"	"114.3"	"160.3"	"192.5"	"279.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13443"	"Disintegrin and metalloproteinase domain-containing protein 9 OS=Homo sapiens OX=9606 GN=ADAM9 PE=1 SV=1"	"1"	"1"	"2"	"1"	"819"	"90.5"	"7.52"	"255.92"	"2.32"	"1"	"1"	"cell adhesion;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00200, Pf01421, Pf01562, Pf08516"	"8754"	"ENSG00000168615"	"ADAM9"	"B7ZLN7; hsa:8754; Q10718; Q13443; Q8NFM6"	"Copper homeostasis; VEGFA-VEGFR2 signaling"	"Collagen degradation"	"3"	"0"	"0.0"	"8.3"	"8.3"	"0.0"	"9.4"	"2.8"	"27.6"	"21.2"	"27.7"	"34.1"	"47.9"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86V48"	"Leucine zipper protein 1 OS=Homo sapiens OX=9606 GN=LUZP1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1076"	"120.2"	"8.50"	"241.76"	"2.32"	"1"	"1"	"developmental processes"	"cytoskeleton;nucleus;other cell component"	""	""	"7798"	"ENSG00000169641"	"LUZP1"	"hsa:7798; Q5TH93; Q86V48; Q8N4X3; Q8TEH1"	"Orexin receptor pathway"	""	"1"	"0"	"6.4"	"14.0"	"9.3"	"6.4"	"11.1"	"7.9"	"15.1"	"10.7"	"17.0"	"17.6"	"16.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5S2"	"Serine/threonine-protein kinase MRCK beta OS=Homo sapiens OX=9606 GN=CDC42BPB PE=1 SV=2"	"1"	"2"	"3"	"2"	"1711"	"194.2"	"6.37"	"515.32"	"2.32"	"2"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00130, Pf00780, Pf08826, Pf15796"	"9578"	"ENSG00000198752"	"CDC42BPB"	"A9JR72; hsa:9578; Q2L7A5; Q86TJ1; Q9ULU5; Q9Y5S2"	"VEGFA-VEGFR2 signaling"	"CDC42 GTPase cycle; RHOQ GTPase cycle; RHOJ GTPase cycle"	"4"	"0"	"26.4"	"46.8"	"55.5"	"16.9"	"58.2"	"37.3"	"67.0"	"61.5"	"102.5"	"224.6"	"241.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q56P03"	"E2F-associated phosphoprotein OS=Homo sapiens OX=9606 GN=EAPP PE=1 SV=4"	"4"	"1"	"1"	"1"	"285"	"32.7"	"5.12"	""	"2.32"	""	"1"	"other biological processes"	"nucleus;other cell component"	""	"Pf10238"	"55837"	"ENSG00000129518"	"EAPP"	"hsa:55837; Q56P03; Q9BVF4; Q9NWV5; Q9NZ86"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6NYC1"	"Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 OS=Homo sapiens OX=9606 GN=JMJD6 PE=1 SV=1"	"3"	"1"	"2"	"1"	"403"	"46.4"	"8.69"	"288.53"	"2.32"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02373"	"23210"	"ENSG00000070495"	"JMJD6"	"B3KMN8; B4DGX1; hsa:23210; Q6NYC1; Q86VY0; Q8IUM5; Q9Y4E2"	""	"HDMs demethylate histones"	"1"	"0"	"5.0"	"23.3"	"19.9"	"7.0"	"20.9"	"8.6"	"66.4"	"27.5"	"26.6"	"35.2"	"55.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86SX6"	"Glutaredoxin-related protein 5, mitochondrial OS=Homo sapiens OX=9606 GN=GLRX5 PE=1 SV=2"	"4"	"1"	"2"	"1"	"157"	"16.6"	"6.79"	"255.19"	"2.31"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00462"	"51218"	"ENSG00000182512"	"GLRX5"	"hsa:51218; Q0X088; Q3YML0; Q86SX6; Q86WY3; Q8IZ54"	"Iron-sulfur cluster biogenesis"	"Mitochondrial iron-sulfur cluster biogenesis"	"2"	"0"	"105.7"	"238.9"	"223.9"	"92.8"	"186.3"	"143.3"	"127.7"	"118.6"	"158.8"	"186.4"	"299.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BPZ3"	"Polyadenylate-binding protein-interacting protein 2 OS=Homo sapiens OX=9606 GN=PAIP2 PE=1 SV=1"	"6"	"1"	"2"	"1"	"127"	"15.0"	"4.12"	"251.30"	"2.31"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other cell component"	"nucleic acid binding activity;other molecular function"	"Pf07145"	"51247"	"ENSG00000120727"	"PAIP2"	"B2RBI1; D3DQC6; hsa:51247; Q49A06; Q9BPZ3; Q9H0Y5; Q9P0Q8"	""	""	"0"	"0"	"112.6"	"221.0"	"230.0"	"98.8"	"247.6"	"129.0"	"222.1"	"174.6"	"220.6"	"267.7"	"341.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BVC6"	"Transmembrane protein 109 OS=Homo sapiens OX=9606 GN=TMEM109 PE=1 SV=1"	"5"	"1"	"2"	"1"	"243"	"26.2"	"10.48"	"375.95"	"2.31"	"1"	"1"	"stress response;transport;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus"	"transporter activity"	"Pf14965"	"79073"	"ENSG00000110108"	"TMEM109"	"hsa:79073; Q9BVC6"	""	""	"0"	"0"	"36.2"	"116.4"	"123.4"	"34.0"	"95.0"	"46.4"	"58.4"	"55.0"	"86.8"	"132.1"	"177.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60716"	"Catenin delta-1 OS=Homo sapiens OX=9606 GN=CTNND1 PE=1 SV=1"	"1"	"1"	"2"	"1"	"968"	"108.1"	"6.23"	"254.69"	"2.31"	"1"	"1"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00514"	"1500"	"ENSG00000198561"	"CTNND1"	"A8K939; hsa:1500; O15088; O60713; O60714; O60715; O60716; O60935; Q6DHZ7; Q6RBX8; Q9UP71; Q9UP72; Q9UP73"	"VEGFA-VEGFR2 signaling; Wnt signaling pathway and pluripotency"	"VEGFR2 mediated vascular permeability; Adherens junctions interactions; InlA-mediated entry of Listeria monocytogenes into host cells; Regulation of CDH11 function; Regulation of CDH19 Expression and Function; CDH11 homotypic and heterotypic interactions"	"8"	"0"	"94.7"	"255.3"	"241.7"	"91.0"	"196.5"	"124.1"	"191.4"	"131.8"	"208.2"	"334.0"	"605.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQ75"	"Protein CMSS1 OS=Homo sapiens OX=9606 GN=CMSS1 PE=1 SV=2"	"3"	"1"	"2"	"1"	"279"	"31.9"	"9.19"	"255.74"	"2.31"	"1"	"1"	""	""	""	"Pf14617"	"84319"	"ENSG00000184220"	"CMSS1"	"A8K5S7; B4DUM1; E9PHS3; hsa:84319; Q9BQ75"	""	""	"0"	"0"	"87.2"	"165.3"	"181.0"	"80.3"	"179.4"	"89.5"	"171.0"	"108.0"	"163.0"	"265.5"	"362.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16850"	"Lanosterol 14-alpha demethylase OS=Homo sapiens OX=9606 GN=CYP51A1 PE=1 SV=3"	"2"	"1"	"2"	"1"	"503"	"56.8"	"8.53"	"280.48"	"2.31"	"1"	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"21.5"	"86.1"	"87.0"	"18.2"	"55.6"	"26.8"	"45.1"	"41.6"	"52.8"	"70.5"	"127.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92552"	"28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3"	"5"	"2"	"3"	"2"	"414"	"47.6"	"6.18"	"747.61"	"2.31"	"2"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf10037"	"23107"	"ENSG00000113048"	"MRPS27"	"B4DRT2; hsa:23107; Q6P1S1; Q92552"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"36.8"	"130.5"	"107.0"	"44.7"	"110.1"	"53.2"	"84.1"	"58.5"	"93.3"	"140.7"	"214.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HD67"	"Unconventional myosin-X OS=Homo sapiens OX=9606 GN=MYO10 PE=1 SV=3"	"0"	"1"	"2"	"1"	"2058"	"237.2"	"6.21"	"286.19"	"2.30"	"1"	"1"	"transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00063, Pf00169, Pf00373, Pf00612, Pf00784, Pf00788, Pf16735, Pf18597"	"4651"	"ENSG00000145555"	"MYO10"	"A7E2D1; hsa:4651; O94893; Q8IVX5; Q9HD67; Q9NYM7; Q9P110; Q9P111; Q9UHF6"	""	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; Netrin-1 signaling"	"3"	"0"	"115.8"	"244.2"	"290.6"	"92.0"	"250.2"	"160.5"	"215.1"	"128.2"	"223.9"	"240.1"	"384.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NRY4"	"Rho GTPase-activating protein 35 OS=Homo sapiens OX=9606 GN=ARHGAP35 PE=1 SV=3"	"1"	"1"	"1"	"1"	"1499"	"170.4"	"6.64"	""	"2.30"	""	"1"	"cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00071, Pf00620, Pf01846, Pf16512, Pf19518"	"2909"	"ENSG00000160007"	"ARHGAP35"	"A7E2A4; hsa:2909; Q14452; Q9C0E1; Q9NRY4"	"Focal adhesion; Regulation of actin cytoskeleton"	"RND3 GTPase cycle; RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOJ GTPase cycle; RND2 GTPase cycle; RHOB GTPase cycle; RHOD GTPase cycle; RND1 GTPase cycle; Sema4D mediated inhibition of cell attachment and migration; PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"	"18"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99798"	"Aconitate hydratase, mitochondrial OS=Homo sapiens OX=9606 GN=ACO2 PE=1 SV=2"	"1"	"1"	"2"	"1"	"780"	"85.4"	"7.61"	"262.48"	"2.30"	"1"	"1"	"other metabolic processes;stress response;developmental processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf00330, Pf00694"	"50"	"ENSG00000100412"	"ACO2"	"hsa:50; O75809; Q5JZ41; Q6FHX0; Q8TAQ6; Q99798"	"Amino acid metabolism; Metabolic reprogramming in colon cancer; Fluoroacetic acid toxicity; TCA cycle (aka Krebs or citric acid cycle)"	"Mitochondrial protein import; Citric acid cycle (TCA cycle)"	"6"	"0"	"14.2"	"96.5"	"74.0"	"7.1"	"68.1"	"21.7"	"26.2"	"20.8"	"23.7"	"35.4"	"65.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P2B7"	"Cilia- and flagella-associated protein 97 OS=Homo sapiens OX=9606 GN=CFAP97 PE=1 SV=2"	"2"	"1"	"1"	"1"	"532"	"59.4"	"9.06"	""	"2.30"	""	"1"	"other biological processes"	""	""	"Pf13879"	"57587"	"ENSG00000164323"	"CFAP97"	"B3KRP7; D3DP60; hsa:57587; Q05CU1; Q4W5M4; Q8N6E7; Q9P2B7; Q9UF45"	""	""	"0"	"0"	"62.4"	"78.1"	"68.9"	"41.7"	"100.2"	"54.7"	"92.9"	"79.3"	"113.8"	"152.0"	"199.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5T4S7"	"E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens OX=9606 GN=UBR4 PE=1 SV=1"	"0"	"1"	"2"	"1"	"5183"	"573.5"	"6.04"	"291.35"	"2.30"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus"	"other molecular function"	"Pf02207, Pf13764, Pf19423"	"23352"	"ENSG00000127481"	"UBR4"	"A8MPT2; A8MQ33; A8MQB1; hsa:23352; O60646; O75050; Q4QRK5; Q5T4S7; Q5T4S8; Q5T4S9; Q5TBN8; Q5TBP2; Q6DKH8; Q6P4A4; Q7L8P7; Q8IXJ4; Q8TDN5; Q8WV67; Q9HA46; Q9P2N9; Q9UG82"	""	"Antigen processing: Ubiquitination & Proteasome degradation; Neutrophil degranulation"	"2"	"0"	"5.3"	"9.4"	"11.3"	"6.3"	"11.1"	"5.0"	"13.6"	"8.5"	"11.5"	"19.7"	"16.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43660"	"Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1"	"2"	"1"	"2"	"1"	"514"	"57.2"	"9.17"	"289.67"	"2.30"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;nucleus;other cell component"	""	"Pf00400"	"5356"	"ENSG00000171566"	"PLRG1"	"B3KMK4; hsa:5356; O43660; Q3KQY5; Q8WUD8"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"67.7"	"165.6"	"286.1"	"85.0"	"167.2"	"104.5"	"299.8"	"205.6"	"253.5"	"377.2"	"524.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96S15"	"GATOR complex protein WDR24 OS=Homo sapiens OX=9606 GN=WDR24 PE=1 SV=2"	"1"	"1"	"2"	"1"	"790"	"88.2"	"6.52"	"365.43"	"2.30"	"1"	"1"	"other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	""	"Pf00400"	"84219"	"ENSG00000127580"	"WDR24"	"A2IDB8; D3DU59; hsa:84219; Q96GC7; Q96S15; Q9H0B7"	""	"Amino acids regulate mTORC1"	"1"	"0"	"10.7"	"21.6"	"21.8"	"6.8"	"16.8"	"10.0"	"22.2"	"16.6"	"31.9"	"48.8"	"64.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13573"	"SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1"	"4"	"3"	"4"	"3"	"536"	"61.5"	"9.52"	"818.50"	"2.29"	"3"	"1"	"RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus"	"signal transduction activity or receptor binding;other molecular function"	"Pf02731"	"22938"	"ENSG00000100603"	"SNW1"	"A8K8A9; hsa:22938; Q13483; Q13573; Q32N03; Q5D0D6"	"Novel intracellular components of RIG-I-like receptor pathway; Splicing factor NOVA regulated synaptic proteins; Notch signaling pathway"	"mRNA Splicing - Major Pathway; Formation of paraxial mesoderm; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Pre-NOTCH Transcription and Translation; Downregulation of SMAD2/3:SMAD4 transcriptional activity; NOTCH1 Intracellular Domain Regulates Transcription; Notch-HLH transcription pathway; NOTCH3 Intracellular Domain Regulates Transcription; Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells; NOTCH4 Intracellular Domain Regulates Transcription; RUNX3 regulates NOTCH signaling"	"15"	"0"	"173.5"	"371.8"	"363.8"	"153.0"	"286.0"	"180.0"	"423.7"	"342.4"	"493.2"	"643.1"	"917.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43847"	"Nardilysin OS=Homo sapiens OX=9606 GN=NRDC PE=1 SV=3"	"1"	"1"	"2"	"1"	"1151"	"131.6"	"4.98"	"301.26"	"2.29"	"1"	"1"	"protein metabolism;other biological processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00675, Pf05193, Pf16187"	"4898"	"ENSG00000078618"	"NRDC"	"A6NI41; hsa:4898; O15241; O15242; O43847; Q5VUL0; Q96HB2; Q9NU57"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3C4"	"EKC/KEOPS complex subunit TPRKB OS=Homo sapiens OX=9606 GN=TPRKB PE=1 SV=1"	"4"	"1"	"2"	"1"	"175"	"19.6"	"6.79"	"312.56"	"2.29"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf08617"	"51002"	"ENSG00000144034"	"TPRKB"	"D6W5H6; hsa:51002; Q8IWR6; Q8IWR7; Q9H3K4; Q9Y3C4"	""	"tRNA modification in the nucleus and cytosol"	"1"	"0"	"14.2"	"48.6"	"42.0"	"15.0"	"36.0"	"15.5"	"45.3"	"30.6"	"38.0"	"57.5"	"82.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NDI1"	"EH domain-binding protein 1 OS=Homo sapiens OX=9606 GN=EHBP1 PE=1 SV=3"	"1"	"1"	"2"	"1"	"1231"	"139.9"	"5.35"	"319.57"	"2.29"	"1"	"1"	"transport"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle"	""	"Pf00307, Pf10358, Pf12130"	"23301"	"ENSG00000115504"	"EHBP1"	"hsa:23301; O94977; Q53TG7; Q53TV6; Q580X2; Q6NX72; Q6PIT3; Q6QNV2; Q8NDI1; Q9NWI9"	"Ciliary landscape"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N3C0"	"Activating signal cointegrator 1 complex subunit 3 OS=Homo sapiens OX=9606 GN=ASCC3 PE=1 SV=3"	"0"	"1"	"1"	"1"	"2202"	"251.3"	"7.09"	""	"2.28"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271, Pf02889"	"10973"	"ENSG00000112249"	"ASCC3"	"E7EW23; hsa:10973; O43738; Q4G1A0; Q5VTN2; Q8N3C0; Q9H1I9; Q9H5A2; Q9NTR0"	"Mesodermal commitment pathway; VEGFA-VEGFR2 signaling"	"ALKBH3 mediated reversal of alkylation damage"	"3"	"0"	"16.6"	"33.2"	"31.1"	"16.0"	"38.6"	"19.0"	"27.4"	"21.8"	"38.8"	"47.8"	"88.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07384"	"Calpain-1 catalytic subunit OS=Homo sapiens OX=9606 GN=CAPN1 PE=1 SV=1"	"1"	"1"	"2"	"1"	"714"	"81.8"	"5.67"	"297.88"	"2.28"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00648, Pf01067, Pf13833"	"823"	"ENSG00000014216"	"CAPN1"	"hsa:823; P07384; Q2TTR0; Q6DHV4"	"Integrin-mediated cell adhesion; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Formation of the cornified envelope; Degradation of the extracellular matrix; Neutrophil degranulation; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"	"7"	"0"	"61.9"	"144.8"	"403.0"	"56.1"	"153.2"	"67.8"	"131.5"	"127.7"	"177.5"	"249.1"	"281.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05089"	"Arginase-1 OS=Homo sapiens OX=9606 GN=ARG1 PE=1 SV=2"	"6"	"1"	"1"	"1"	"322"	"34.7"	"7.21"	""	"2.28"	""	"1"	"other metabolic processes;stress response;developmental processes;other biological processes"	"non-structural extracellular;other membranes;cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00491"	"383"	"ENSG00000118520"	"ARG1"	"A6NEA0; hsa:383; P05089; Q5JWT5; Q5JWT6; Q8TE72; Q9BS50"	"Spinal cord injury; Amino acid metabolism; IL-18 signaling pathway"	"Neutrophil degranulation; Urea cycle"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N4T8"	"Carbonyl reductase family member 4 OS=Homo sapiens OX=9606 GN=CBR4 PE=1 SV=3"	"3"	"1"	"2"	"1"	"237"	"25.3"	"9.33"	"293.73"	"2.28"	"1"	"1"	"cell organization and biogenesis;other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf13561"	"84869"	"ENSG00000145439"	"CBR4"	"hsa:84869; Q8N4T8; Q8WTW8; Q96K93"	""	"Fatty acyl-CoA biosynthesis"	"1"	"0"	"16.6"	"32.7"	"26.3"	"10.7"	"25.0"	"12.7"	"132.0"	"136.2"	"184.2"	"280.9"	"428.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61201"	"COP9 signalosome complex subunit 2 OS=Homo sapiens OX=9606 GN=COPS2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"443"	"51.6"	"5.53"	"279.03"	"2.27"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01399"	"9318"	"ENSG00000166200"	"COPS2"	"hsa:9318; O88950; P61201; Q15647; Q6FGP4; Q9BY54; Q9R249; Q9UNI2; Q9UNQ5"	"Ciliary landscape"	"Neddylation; Cargo recognition for clathrin-mediated endocytosis; Formation of TC-NER Pre-Incision Complex; RHOBTB1 GTPase cycle; DNA Damage Recognition in GG-NER"	"6"	"0"	"53.3"	"142.7"	"155.3"	"51.4"	"170.5"	"81.4"	"106.0"	"67.6"	"115.1"	"133.7"	"205.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07954"	"Fumarate hydratase, mitochondrial OS=Homo sapiens OX=9606 GN=FH PE=1 SV=3"	"2"	"1"	"2"	"1"	"510"	"54.6"	"8.76"	"238.44"	"2.27"	"1"	"1"	"DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00206, Pf10415"	"2271"	"ENSG00000091483"	"FH"	"B1ANK7; hsa:2271; P07954"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Krebs cycle disorders; Type 2 papillary renal cell carcinoma; Metabolic reprogramming in colon cancer; TCA cycle in senescence; TCA cycle (aka Krebs or citric acid cycle)"	"Citric acid cycle (TCA cycle)"	"8"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BRX5"	"DNA replication complex GINS protein PSF3 OS=Homo sapiens OX=9606 GN=GINS3 PE=1 SV=1"	"4"	"1"	"2"	"1"	"216"	"24.5"	"5.34"	"237.62"	"2.27"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"nucleus"	""	"Pf05916"	"64785"	"ENSG00000181938"	"GINS3"	"B2RDP3; E9PB21; hsa:64785; Q9BRX5; Q9H870"	""	"Unwinding of DNA"	"1"	"0"	"28.2"	"146.3"	"108.7"	"27.3"	"99.8"	"37.6"	"45.3"	"33.2"	"40.3"	"57.0"	"125.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13423"	"NAD(P) transhydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=NNT PE=1 SV=3"	"1"	"1"	"2"	"1"	"1086"	"113.8"	"8.09"	"288.06"	"2.27"	"1"	"1"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf01262, Pf02233, Pf05222, Pf12769"	"23530"	"ENSG00000112992"	"NNT"	"hsa:23530; Q13423; Q16796; Q2TB60; Q8N3V4"	""	"Citric acid cycle (TCA cycle)"	"1"	"0"	"38.4"	"109.4"	"111.5"	"37.4"	"96.4"	"47.5"	"62.5"	"58.4"	"73.8"	"110.2"	"172.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95298"	"NADH dehydrogenase [ubiquinone] 1 subunit C2 OS=Homo sapiens OX=9606 GN=NDUFC2 PE=1 SV=1"	"6"	"1"	"1"	"1"	"119"	"14.2"	"8.98"	""	"2.27"	""	"1"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;mitochondrion;other cytoplasmic organelle;other cell component"	"transporter activity"	"Pf06374"	"4718"	"ENSG00000151366"	"NDUFC2"	"E9PNU8; E9PRB2; hsa:4718; O95298; Q549M5; Q6FIH8; Q9UBJ9"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Neutrophil degranulation; Complex I biogenesis"	"6"	"0"	"63.8"	"288.9"	"229.1"	"76.8"	"224.1"	"84.4"	"115.3"	"80.5"	"122.7"	"171.6"	"270.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKV5"	"E3 ubiquitin-protein ligase AMFR OS=Homo sapiens OX=9606 GN=AMFR PE=1 SV=2"	"2"	"1"	"1"	"1"	"643"	"72.9"	"6.39"	""	"2.26"	""	"1"	"cell-cell signaling;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf02845, Pf13639, Pf18442"	"267"	"ENSG00000159461"	"AMFR"	"hsa:267; P26442; Q8IZ70; Q9UKV5"	"Sterol regulatory element-binding proteins (SREBP) signaling"	"ER Quality Control Compartment (ERQC); N-glycan trimming in the ER and Calnexin/Calreticulin cycle"	"3"	"0"	"8.7"	"12.6"	"11.0"	"10.1"	"12.7"	"11.4"	"12.2"	"15.2"	"25.5"	"26.9"	"36.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96NW4"	"Ankyrin repeat domain-containing protein 27 OS=Homo sapiens OX=9606 GN=ANKRD27 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1050"	"116.9"	"6.87"	"275.05"	"2.26"	"1"	"1"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02204, Pf12796"	"84079"	"ENSG00000105186"	"ANKRD27"	"hsa:84079; Q71MF5; Q86UC3; Q8ND80; Q96NW4; Q9H0I4"	""	"RAB GEFs exchange GTP for GDP on RABs"	"1"	"0"	"15.8"	"63.5"	"55.8"	"20.9"	"44.8"	"24.1"	"51.9"	"42.1"	"44.3"	"61.3"	"93.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N543"	"Prolyl 3-hydroxylase OGFOD1 OS=Homo sapiens OX=9606 GN=OGFOD1 PE=1 SV=1"	"1"	"1"	"1"	"1"	"542"	"63.2"	"5.11"	""	"2.26"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf10637, Pf13661"	"55239"	"ENSG00000087263"	"OGFOD1"	"H3BUQ2; hsa:55239; Q8N543; Q9H7U5; Q9H9J9; Q9HA87; Q9HCG0; Q9NVB6"	""	""	"0"	"0"	"43.9"	"109.3"	"97.0"	"44.6"	"104.2"	"49.2"	"90.5"	"95.3"	"196.2"	"245.8"	"344.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NUQ2"	"1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon OS=Homo sapiens OX=9606 GN=AGPAT5 PE=1 SV=3"	"2"	"1"	"1"	"1"	"364"	"42.0"	"9.10"	""	"2.26"	""	"1"	"other metabolic processes;other biological processes"	"other membranes;mitochondrion;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf01553, Pf16076"	"55326"	"ENSG00000155189; ENSG00000284980"	"AGPAT5"	"hsa:55326; Q8IZ47; Q9BQG4; Q9NUQ2"	"Triacylglyceride synthesis"	"Synthesis of PA"	"2"	"0"	"108.9"	"143.8"	"171.7"	"103.3"	"150.1"	"128.5"	"140.6"	"101.7"	"148.2"	"171.6"	"216.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96MG7"	"Non-structural maintenance of chromosomes element 3 homolog OS=Homo sapiens OX=9606 GN=NSMCE3 PE=1 SV=1"	"4"	"1"	"2"	"1"	"304"	"34.3"	"9.28"	"319.43"	"2.26"	"1"	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf01454"	"56160"	"ENSG00000185115; ENSG00000282130"	"NSMCE3"	"hsa:56160; Q8IW16; Q8TEI6; Q96MG7; Q9H214"	""	"SUMOylation of DNA damage response and repair proteins"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NRZ9"	"Lymphoid-specific helicase OS=Homo sapiens OX=9606 GN=HELLS PE=1 SV=1"	"2"	"2"	"2"	"2"	"838"	"97.0"	"7.93"	"281.87"	"2.26"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00176, Pf00271"	"3070"	"ENSG00000119969"	"HELLS"	"B2RB41; hsa:3070; Q3LID1; Q6I7N7; Q76H76; Q76H77; Q76H78; Q76H79; Q76H80; Q76H81; Q7Z397; Q7Z5X2; Q8N6P4; Q9H4P5; Q9NRZ9"	"Apoptosis; Apoptosis-related network due to altered Notch3 in ovarian cancer"	""	"2"	"0"	"85.3"	"184.3"	"165.4"	"79.8"	"177.0"	"90.2"	"174.7"	"146.1"	"214.9"	"287.8"	"449.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5JVS0"	"Intracellular hyaluronan-binding protein 4 OS=Homo sapiens OX=9606 GN=HABP4 PE=1 SV=1"	"2"	"1"	"2"	"1"	"413"	"45.8"	"7.46"	"277.39"	"2.25"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"non-structural extracellular;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04774, Pf16174"	"22927"	"ENSG00000130956"	"HABP4"	"hsa:22927; O75804; Q5JVS0; Q8WV33; Q9NYJ2"	""	"Platelet degranulation"	"1"	"0"	"93.1"	"250.6"	"194.9"	"67.5"	"197.9"	"92.9"	"164.2"	"132.1"	"195.7"	"200.3"	"318.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12899"	"Tripartite motif-containing protein 26 OS=Homo sapiens OX=9606 GN=TRIM26 PE=1 SV=1"	"5"	"2"	"3"	"2"	"539"	"62.1"	"5.03"	"525.44"	"2.25"	"2"	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00622, Pf00643, Pf13765, Pf15227"	"7726"	"ENSG00000137313; ENSG00000226060; ENSG00000228881; ENSG00000230230; ENSG00000231002; ENSG00000231641; ENSG00000234046; ENSG00000234127"	"TRIM26"	"A6NG96; hsa:7726; Q12899; Q5SRL2"	""	"Interferon gamma signaling"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBM7"	"7-dehydrocholesterol reductase OS=Homo sapiens OX=9606 GN=DHCR7 PE=1 SV=1"	"2"	"1"	"2"	"1"	"475"	"54.5"	"8.70"	"237.73"	"2.24"	"1"	"1"	"other metabolic processes;other biological processes"	"other membranes;ER/Golgi;nucleus"	"other molecular function"	"Pf01222"	"1717"	"ENSG00000172893"	"DHCR7"	"B2R6Z2; hsa:1717; O60492; O60717; Q9UBM7"	"Vitamin D metabolism; Cholesterol biosynthesis pathway; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Cholesterol biosynthesis with skeletal dysplasias; Cholesterol synthesis disorders; Cholesterol metabolism; Enterocyte cholesterol metabolism"	"Activation of gene expression by SREBF (SREBP); Cholesterol biosynthesis via desmosterol; Cholesterol biosynthesis via lathosterol"	"10"	"0"	"101.8"	"237.7"	"236.5"	"90.1"	"226.1"	"101.6"	"195.5"	"149.6"	"220.8"	"311.2"	"449.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92506"	"Estradiol 17-beta-dehydrogenase 8 OS=Homo sapiens OX=9606 GN=HSD17B8 PE=1 SV=2"	"3"	"1"	"2"	"1"	"261"	"27.0"	"6.54"	"291.09"	"2.24"	"1"	"1"	"cell organization and biogenesis;other metabolic processes"	"plasma membrane;other membranes;mitochondrion;other cell component"	"other molecular function"	"Pf13561"	"7923"	"ENSG00000112474; ENSG00000204228; ENSG00000225312; ENSG00000228357; ENSG00000228712; ENSG00000232357"	"HSD17B8"	"A6NLX7; hsa:7923; Q5STP7; Q92506; Q9UIQ1"	""	"Fatty acyl-CoA biosynthesis"	"1"	"0"	"28.5"	"47.0"	"61.0"	"20.0"	"77.2"	"36.5"	"128.1"	"105.3"	"150.6"	"199.2"	"294.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13535"	"Serine/threonine-protein kinase ATR OS=Homo sapiens OX=9606 GN=ATR PE=1 SV=3"	"1"	"1"	"1"	"1"	"2644"	"301.2"	"7.43"	""	"2.24"	""	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00454, Pf02259, Pf02260, Pf08064"	"545"	"ENSG00000175054"	"ATR"	"hsa:545; Q13535; Q59HB2; Q7KYL3; Q93051; Q9BXK4"	"miRNA regulation of DNA damage response; Cell cycle; ATR signaling; ATM signaling in development and disease ; Breast cancer pathway; DNA repair pathways, full network; NIPBL role in DNA damage - Cornelia de Lange syndrome; DNA damage response"	"Meiotic synapsis; Fanconi Anemia Pathway; Regulation of HSF1-mediated heat shock response; TP53 Regulates Transcription of DNA Repair Genes; Regulation of TP53 Activity through Phosphorylation; Activation of ATR in response to replication stress; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51"	"19"	"0"	"27.1"	"48.9"	"56.0"	"21.2"	"52.3"	"36.0"	"100.5"	"67.9"	"102.7"	"93.0"	"140.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H3U1"	"Protein unc-45 homolog A OS=Homo sapiens OX=9606 GN=UNC45A PE=1 SV=1"	"1"	"1"	"2"	"1"	"944"	"103.0"	"6.07"	"263.41"	"2.24"	"1"	"1"	"other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf11701, Pf13181, Pf13432"	"55898"	"ENSG00000140553"	"UNC45A"	"A8K6F7; hsa:55898; Q7L3Y6; Q9H3U1; Q9H3U8; Q9NSE8; Q9NSE9"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NRX2"	"39S ribosomal protein L17, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL17 PE=1 SV=1"	"5"	"1"	"3"	"1"	"175"	"20.0"	"10.11"	"496.35"	"2.24"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf01196"	"63875"	"ENSG00000158042"	"MRPL17"	"D3DQU3; hsa:63875; Q6IAH8; Q96Q53; Q9C066; Q9NRX2"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"69.3"	"183.0"	"186.4"	"61.0"	"152.0"	"83.5"	"116.3"	"102.8"	"163.8"	"246.1"	"379.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N122"	"Regulatory-associated protein of mTOR OS=Homo sapiens OX=9606 GN=RPTOR PE=1 SV=1"	"1"	"1"	"1"	"1"	"1335"	"148.9"	"6.89"	""	"2.24"	""	"1"	"cell organization and biogenesis;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00400, Pf02985, Pf14538"	"57521"	"ENSG00000141564"	"RPTOR"	"B2RN36; C6KEF2; F5H7J5; hsa:57521; Q8N122; Q8N4V9; Q8TB32; Q9P2P3"	"AMP-activated protein kinase signaling; Target of rapamycin signaling; PI3K-AKT-mTOR signaling pathway and therapeutic opportunities; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Clear cell renal cell carcinoma pathways; PI3K-Akt signaling pathway; Thermogenesis; Synaptic signaling pathways associated with autism spectrum disorder; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Head and neck squamous cell carcinoma; Thyroid hormones production and peripheral downstream signaling effects; IL-18 signaling pathway; CAMKK2 pathway; Autophagy; p53 transcriptional gene network; Pleural mesothelioma; Network map of SARS-CoV-2 signaling pathway; GDNF signaling; DYRK1A involvement regarding cell proliferation in brain development; JAK-STAT signaling in the regulation of Beta-cells; Interferon type I signaling pathways"	"Regulation of PTEN gene transcription; TP53 Regulates Metabolic Genes; Amino acids regulate mTORC1; mTORC1-mediated signalling; Macroautophagy; Energy dependent regulation of mTOR by LKB1-AMPK; HSF1-dependent transactivation"	"33"	"0"	"4.7"	"14.8"	"13.9"	"4.8"	"8.4"	"5.0"	"11.6"	"10.3"	"13.9"	"17.8"	"23.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"G2XKQ0"	"Small ubiquitin-related modifier 5 OS=Homo sapiens OX=9606 GN=SUMO1P1 PE=1 SV=2"	"7"	"1"	"1"	"1"	"101"	"11.5"	"5.52"	""	"2.24"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"nucleus"	"other molecular function"	"Pf11976"	""	""	"SUMO1P1"	"G2XKQ0"	""	""	"0"	"0"	"63.9"	"364.5"	"276.9"	"38.3"	"256.8"	"92.3"	"134.1"	"98.7"	"142.7"	"195.2"	"385.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P43897"	"Elongation factor Ts, mitochondrial OS=Homo sapiens OX=9606 GN=TSFM PE=1 SV=2"	"2"	"1"	"2"	"1"	"325"	"35.4"	"8.38"	"309.43"	"2.24"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"mitochondrion;nucleus"	"nucleic acid binding activity"	"Pf00889"	"10102"	"ENSG00000123297"	"TSFM"	"B4E391; F5H2T7; hsa:10102; P43897; Q561V7; Q8TBC2; Q9UQK0"	""	"Mitochondrial translation elongation"	"1"	"0"	"52.6"	"124.4"	"112.4"	"43.1"	"107.8"	"61.1"	"90.5"	"61.0"	"94.2"	"97.1"	"159.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H3G5"	"Probable serine carboxypeptidase CPVL OS=Homo sapiens OX=9606 GN=CPVL PE=1 SV=2"	"4"	"2"	"3"	"2"	"476"	"54.1"	"5.62"	"494.54"	"2.24"	"2"	"1"	"protein metabolism"	""	"other molecular function"	"Pf00450"	"54504"	"ENSG00000106066"	"CPVL"	"A4D1A4; hsa:54504; Q6UX20; Q8NBL7; Q96AR7; Q9H3G5; Q9HB41"	""	""	"0"	"0"	"27.4"	"52.1"	"63.3"	"23.4"	"59.7"	"29.1"	"60.1"	"51.5"	"78.6"	"103.5"	"184.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P38935"	"DNA-binding protein SMUBP-2 OS=Homo sapiens OX=9606 GN=IGHMBP2 PE=1 SV=3"	"1"	"1"	"1"	"1"	"993"	"109.1"	"8.97"	""	"2.24"	""	"1"	"cell organization and biogenesis;RNA metabolism OR transcription"	"nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf01424, Pf01428, Pf13086, Pf13087"	"3508"	"ENSG00000132740"	"IGHMBP2"	"A0PJD2; hsa:3508; P38935; Q00443; Q14177"	""	""	"0"	"0"	"3.0"	"8.7"	"10.1"	"4.2"	"6.9"	"3.1"	"12.9"	"9.6"	"17.0"	"30.8"	"47.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NVH6"	"Trimethyllysine dioxygenase, mitochondrial OS=Homo sapiens OX=9606 GN=TMLHE PE=1 SV=1"	"2"	"1"	"1"	"1"	"421"	"49.5"	"7.72"	""	"2.23"	""	"1"	"other metabolic processes;other biological processes"	"mitochondrion"	"other molecular function"	"Pf02668, Pf06155"	"55217"	"ENSG00000185973"	"TMLHE"	"A8K6M9; B4E3R3; hsa:55217; Q5TZB5; Q6IA90; Q8TBT0; Q9NVH6"	""	"Carnitine synthesis"	"1"	"0"	"33.5"	"62.0"	"67.3"	"31.9"	"73.4"	"42.1"	"76.4"	"49.1"	"81.6"	"155.2"	"175.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BYT8"	"Neurolysin, mitochondrial OS=Homo sapiens OX=9606 GN=NLN PE=1 SV=1"	"2"	"1"	"1"	"1"	"704"	"80.6"	"6.64"	""	"2.23"	""	"1"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;mitochondrion"	"other molecular function"	"Pf01432"	"57486"	"ENSG00000123213"	"NLN"	"hsa:57486; Q9BYT8; Q9ULJ4"	""	"Peptide ligand-binding receptors"	"1"	"0"	"6.9"	"41.4"	"38.3"	"5.6"	"24.9"	"10.4"	"19.9"	"16.9"	"23.6"	"40.9"	"46.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UPU5"	"Ubiquitin carboxyl-terminal hydrolase 24 OS=Homo sapiens OX=9606 GN=USP24 PE=1 SV=3"	"0"	"1"	"1"	"1"	"2620"	"294.2"	"6.14"	""	"2.23"	""	"1"	"protein metabolism;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf00443, Pf12030"	"23358"	"ENSG00000162402"	"USP24"	"hsa:23358; Q6ZSY2; Q8N2Y4; Q9NXD1; Q9UPU5"	""	"Ub-specific processing proteases"	"1"	"0"	"26.2"	"61.0"	"58.4"	"32.0"	"61.2"	"30.9"	"70.9"	"61.0"	"84.2"	"79.1"	"109.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NBF2"	"NHL repeat-containing protein 2 OS=Homo sapiens OX=9606 GN=NHLRC2 PE=1 SV=1"	"1"	"1"	"2"	"1"	"726"	"79.4"	"5.55"	"270.08"	"2.23"	"1"	"1"	""	"non-structural extracellular;cytosol;other cell component"	""	"Pf01436, Pf13905"	"374354"	"ENSG00000196865"	"NHLRC2"	"hsa:374354; Q8N1H1; Q8N5A6; Q8NBF2"	""	"Platelet degranulation"	"1"	"0"	"10.2"	"65.1"	"52.6"	"5.6"	"52.7"	"12.9"	"22.6"	"14.2"	"27.0"	"32.7"	"62.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00154"	"Cytosolic acyl coenzyme A thioester hydrolase OS=Homo sapiens OX=9606 GN=ACOT7 PE=1 SV=3"	"3"	"1"	"2"	"1"	"380"	"41.8"	"8.54"	"236.94"	"2.23"	"1"	"1"	"other metabolic processes"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf03061"	"11332"	"ENSG00000097021"	"ACOT7"	"A8K0K7; A8K232; A8K6B8; A8K837; B3KQ12; hsa:11332; O00154; O43703; Q53Y78; Q5JYL2; Q5JYL3; Q5JYL4; Q5JYL5; Q5JYL6; Q5TGR4; Q9UJM9; Q9Y539; Q9Y540"	""	"Mitochondrial Fatty Acid Beta-Oxidation"	"1"	"0"	"5.8"	"29.7"	"23.1"	"3.6"	"18.6"	"6.5"	"9.1"	"9.9"	"9.1"	"18.5"	"27.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4E8"	"Ubiquitin carboxyl-terminal hydrolase 15 OS=Homo sapiens OX=9606 GN=USP15 PE=1 SV=3"	"2"	"2"	"3"	"2"	"981"	"112.3"	"5.22"	"535.08"	"2.22"	"2"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00443, Pf06337, Pf14533, Pf14836"	"9958"	"ENSG00000135655"	"USP15"	"hsa:9958; Q08AL5; Q9H8G9; Q9HCA6; Q9UNP0; Q9Y4E8; Q9Y5B5"	""	"Ub-specific processing proteases; UCH proteinases; Downregulation of TGF-beta receptor signaling"	"3"	"0"	"67.0"	"134.4"	"134.5"	"55.0"	"133.9"	"68.5"	"91.4"	"95.7"	"109.3"	"152.7"	"219.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11413"	"Glucose-6-phosphate 1-dehydrogenase OS=Homo sapiens OX=9606 GN=G6PD PE=1 SV=4"	"2"	"1"	"1"	"1"	"515"	"59.2"	"6.84"	""	"2.22"	""	"1"	"other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00479, Pf02781"	"2539"	"ENSG00000160211"	"G6PD"	"D3DWX9; hsa:2539; P11413; Q16000; Q16765; Q8IU70; Q8IU88; Q8IUA6; Q96PQ2"	"Glutathione metabolism; Pentose phosphate metabolism; Cori cycle; Vitamin D receptor pathway; Nuclear receptors meta-pathway; NRF2 pathway; ATM signaling in development and disease ; Metabolic reprogramming in colon cancer; Vitamin D-sensitive calcium signaling in depression; Pentose phosphate pathway in senescent cells; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Glycolysis in senescence; Sulfation biotransformation reaction"	"TP53 Regulates Metabolic Genes; NFE2L2 regulates pentose phosphate pathway genes; Pentose phosphate pathway"	"16"	"0"	"19.0"	"19.2"	"23.3"	"18.2"	"19.6"	"22.8"	"24.0"	"22.5"	"40.1"	"50.9"	"75.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43598"	"2'-deoxynucleoside 5'-phosphate N-hydrolase 1 OS=Homo sapiens OX=9606 GN=DNPH1 PE=1 SV=1"	"3"	"1"	"1"	"1"	"174"	"19.1"	"5.05"	""	"2.22"	""	"1"	"other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf05014"	"10591"	"ENSG00000112667"	"DNPH1"	"B2LUJ9; hsa:10591; O43598"	""	"Purine catabolism"	"1"	"0"	"24.1"	"264.7"	"217.0"	"21.4"	"147.3"	"47.3"	"70.6"	"58.6"	"71.5"	"78.4"	"154.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q659A1"	"Little elongation complex subunit 2 OS=Homo sapiens OX=9606 GN=ICE2 PE=1 SV=2"	"1"	"1"	"1"	"1"	"982"	"109.9"	"7.09"	""	"2.22"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf10505"	"79664"	"ENSG00000128915"	"ICE2"	"B2RU08; hsa:79664; Q05CT1; Q3B7W6; Q63HP4; Q658Q0; Q659A1; Q68CN8; Q6IPW7; Q6UX23; Q71H65; Q96CY5; Q9HAA2"	""	"RNA polymerase II transcribes snRNA genes"	"1"	"0"	"94.7"	"179.4"	"177.0"	"96.9"	"167.9"	"90.4"	"449.5"	"366.0"	"471.5"	"471.5"	"635.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95373"	"Importin-7 OS=Homo sapiens OX=9606 GN=IPO7 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1038"	"119.4"	"4.82"	"247.23"	"2.22"	"1"	"1"	"stress response;transport;other biological processes"	"cytosol;nucleus"	"enzyme regulator activity;other molecular function"	"Pf03810, Pf08506"	"10527"	"ENSG00000205339"	"IPO7"	"A6NNM5; B2R786; hsa:10527; O95373; Q1RMF7; Q9H177; Q9NTE3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15434"	"RNA-binding motif, single-stranded-interacting protein 2 OS=Homo sapiens OX=9606 GN=RBMS2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"407"	"43.9"	"9.07"	"333.94"	"2.22"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"5939"	"ENSG00000076067"	"RBMS2"	"hsa:5939; Q15434"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q16555"	"Dihydropyrimidinase-related protein 2 OS=Homo sapiens OX=9606 GN=DPYSL2 PE=1 SV=1"	"2"	"1"	"1"	"1"	"572"	"62.3"	"6.38"	""	"2.21"	""	"1"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton"	"other molecular function"	"Pf01979"	"1808"	"ENSG00000092964"	"DPYSL2"	"A8K5H2; B4DR31; D3DSS7; hsa:1808; O00424; Q16555"	"Microtubule cytoskeleton regulation; Brain-derived neurotrophic factor (BDNF) signaling pathway"	"CRMPs in Sema3A signaling; Recycling pathway of L1"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q147X3"	"N-alpha-acetyltransferase 30 OS=Homo sapiens OX=9606 GN=NAA30 PE=1 SV=1"	"2"	"1"	"2"	"1"	"362"	"39.3"	"5.52"	"259.19"	"2.21"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00583"	"122830"	"ENSG00000139977"	"NAA30"	"hsa:122830; Q0IIN2; Q147X3"	"Metapathway biotransformation Phase I and II"	"Retrograde transport at the Trans-Golgi-Network"	"2"	"0"	"16.2"	"34.6"	"42.7"	"18.1"	"31.3"	"21.2"	"47.1"	"40.3"	"65.2"	"92.6"	"147.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q67FW5"	"UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1 OS=Homo sapiens OX=9606 GN=B3GNTL1 PE=2 SV=2"	"2"	"1"	"1"	"1"	"361"	"40.7"	"7.40"	""	"2.21"	""	"1"	""	""	"other molecular function"	"Pf00535"	"146712"	"ENSG00000175711; ENSG00000277033"	"B3GNTL1"	"hsa:146712; Q67FW5; Q6GV30; Q8WUT3"	""	"O-linked glycosylation of mucins"	"1"	"0"	"15.9"	"22.9"	"17.4"	"11.1"	"21.7"	"15.1"	"32.2"	"66.4"	"317.6"	"831.1"	"1316.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q4LDG9"	"Dynein light chain 1, axonemal OS=Homo sapiens OX=9606 GN=DNAL1 PE=1 SV=1"	"4"	"1"	"2"	"1"	"190"	"21.5"	"6.10"	"267.09"	"2.21"	"1"	"1"	"cell organization and biogenesis"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	""	"83544"	"ENSG00000119661"	"DNAL1"	"B2RD38; hsa:83544; Q4LDG9; Q5JPB7; Q9BS43"	"Ciliopathies"	""	"1"	"0"	"144.0"	"210.1"	"198.0"	"113.1"	"187.3"	"126.7"	"215.1"	"187.8"	"233.9"	"299.2"	"372.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75083"	"WD repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=WDR1 PE=1 SV=4"	"2"	"1"	"1"	"1"	"606"	"66.2"	"6.65"	""	"2.20"	""	"1"	"cell organization and biogenesis;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf00400"	"9948"	"ENSG00000071127"	"WDR1"	"A8K6E9; A8MPU4; hsa:9948; O75083; O75313; Q8N6E5; Q9UG05; Q9UG78; Q9UQE0"	"Hypertrophy model"	"Platelet degranulation"	"2"	"0"	"3.9"	"18.8"	"7.8"	"4.1"	"13.1"	"4.2"	"7.2"	"8.4"	"7.5"	"15.8"	"24.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P49591"	"Serine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=SARS1 PE=1 SV=3"	"12"	"5"	"6"	"5"	"514"	"58.7"	"6.43"	"1451.19"	"2.20"	"4"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00587, Pf02403"	"6301"	"ENSG00000031698"	"SARS1"	"B2R6Y9; hsa:6301; P49591; Q5T5C8; Q9NSE3"	"VEGFA-VEGFR2 signaling"	"Cytosolic tRNA aminoacylation; Selenocysteine synthesis"	"3"	"0"	"81.7"	"398.6"	"332.1"	"38.7"	"279.4"	"78.5"	"126.2"	"101.4"	"144.7"	"215.3"	"426.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P86790"	"Vacuolar fusion protein CCZ1 homolog B OS=Homo sapiens OX=9606 GN=CCZ1B PE=1 SV=1"	"3"	"1"	"2"	"1"	"482"	"55.8"	"6.48"	"280.03"	"2.20"	"1"	"1"	"transport"	"other membranes;other cytoplasmic organelle;other cell component"	""	"Pf19031, Pf19032, Pf19033"	"221960; 51622"	"ENSG00000146574"	"CCZ1B"	"A2RU45; hsa:221960; hsa:51622; O95766; P86790; Q9UG65; Q9Y359"	""	"RAB GEFs exchange GTP for GDP on RABs"	"1"	"0"	"7.6"	"30.8"	"40.2"	"12.4"	"27.3"	"11.9"	"31.8"	"20.6"	"33.3"	"49.3"	"87.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P1L8"	"39S ribosomal protein L14, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL14 PE=1 SV=1"	"6"	"1"	"1"	"1"	"145"	"15.9"	"10.24"	""	"2.20"	""	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00238"	"64928"	"ENSG00000180992"	"MRPL14"	"B2R575; hsa:64928; Q6P1L8; Q96Q72"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"14.2"	"33.2"	"27.3"	"11.1"	"30.4"	"17.2"	"26.0"	"27.8"	"33.9"	"43.4"	"49.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y613"	"FH1/FH2 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=FHOD1 PE=1 SV=3"	"1"	"1"	"2"	"1"	"1164"	"126.5"	"6.39"	"272.82"	"2.20"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02181, Pf18382"	"29109"	"ENSG00000135723"	"FHOD1"	"hsa:29109; Q59F76; Q6Y1F2; Q76MS8; Q8N521; Q9Y613"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12894"	"Interferon-related developmental regulator 2 OS=Homo sapiens OX=9606 GN=IFRD2 PE=1 SV=3"	"2"	"1"	"2"	"1"	"506"	"54.8"	"7.94"	"239.39"	"2.20"	"1"	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"4.0"	"14.8"	"17.3"	"6.7"	"12.2"	"8.6"	"16.8"	"9.8"	"17.8"	"24.2"	"36.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UPP2"	"IQ motif and SEC7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=IQSEC3 PE=2 SV=3"	"1"	"1"	"2"	"1"	"1182"	"127.5"	"6.51"	"252.78"	"2.20"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf01369, Pf16453"	"440073"	"ENSG00000120645; ENSG00000262607"	"IQSEC3"	"A6NIF2; A6NKV9; hsa:440073; Q8TB43; Q9UPP2"	""	"NPAS4 regulates expression of target genes"	"1"	"0"	"12.7"	"23.9"	"23.3"	"9.0"	"15.0"	"8.5"	"67.0"	"57.0"	"86.0"	"131.7"	"243.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P000"	"COMM domain-containing protein 9 OS=Homo sapiens OX=9606 GN=COMMD9 PE=1 SV=2"	"6"	"1"	"1"	"1"	"198"	"21.8"	"5.88"	""	"2.20"	""	"1"	"transport;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;nucleus;other cell component"	""	"Pf07258"	"29099"	"ENSG00000110442"	"COMMD9"	"E9PAN2; hsa:29099; Q96FI2; Q9H0R0; Q9P000"	""	"Neutrophil degranulation; Neddylation"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15004"	"PCNA-associated factor OS=Homo sapiens OX=9606 GN=PCLAF PE=1 SV=1"	"8"	"1"	"2"	"1"	"111"	"12.0"	"9.83"	"256.56"	"2.20"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf15715"	"9768"	"ENSG00000166803"	"PCLAF"	"A6NNU5; A8K3Y3; G9G694; G9G696; hsa:9768; Q15004"	""	"Termination of translesion DNA synthesis"	"1"	"0"	"3.9"	"9.9"	"6.9"	"3.7"	"4.7"	"2.3"	"20.9"	"24.4"	"26.5"	"37.5"	"63.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NVA1"	"Ubiquinol-cytochrome-c reductase complex assembly factor 1 OS=Homo sapiens OX=9606 GN=UQCC1 PE=1 SV=3"	"4"	"1"	"2"	"1"	"299"	"34.6"	"8.91"	"237.11"	"2.19"	"1"	"1"	"cell organization and biogenesis"	"other membranes;mitochondrion;other cell component"	""	"Pf03981"	"55245"	"ENSG00000101019"	"UQCC1"	"B1AKV5; hsa:55245; Q0VF37; Q5T348; Q5T351; Q5T353; Q86YU3; Q86YU4; Q96H66; Q9H438; Q9H452; Q9H9K8; Q9H9R5; Q9NVA1"	"Ciliary landscape; Mitochondrial complex III assembly"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P11233"	"Ras-related protein Ral-A OS=Homo sapiens OX=9606 GN=RALA PE=1 SV=1"	"3"	"1"	"1"	"1"	"206"	"23.6"	"7.11"	""	"2.19"	""	"1"	"cell cycle OR cell proliferation;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;mitochondrion;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00071"	"5898"	"ENSG00000006451"	"RALA"	"A4D1W3; hsa:5898; P11233"	"RalA downstream regulated genes; Chromosomal and microsatellite instability in colorectal cancer ; Ras signaling; Pancreatic adenocarcinoma pathway; EGF/EGFR signaling pathway"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Translocation of SLC2A4 (GLUT4) to the plasma membrane; p38MAPK events"	"8"	"0"	"20.2"	"64.7"	"83.9"	"22.5"	"40.4"	"22.4"	"46.2"	"42.5"	"49.6"	"71.6"	"108.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P35240"	"Merlin OS=Homo sapiens OX=9606 GN=NF2 PE=1 SV=1"	"2"	"1"	"1"	"1"	"595"	"69.6"	"6.47"	""	"2.19"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity"	"Pf00373, Pf00769, Pf09379, Pf09380, Pf20492"	"4771"	"ENSG00000186575"	"NF2"	"hsa:4771; O95683; P35240; Q8WUJ2; Q969N0; Q969Q3; Q96T30; Q96T31; Q96T32; Q96T33; Q9BTW3; Q9UNG9; Q9UNH3; Q9UNH4"	"Ectoderm differentiation; Ectoderm differentiation; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-YAP signaling; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; 3q29 copy number variation syndrome; Pleural mesothelioma"	"Regulation of actin dynamics for phagocytic cup formation; RHO GTPases activate PAKs"	"10"	"0"	"7.1"	"7.0"	"11.2"	"3.6"	"4.7"	"4.1"	"9.4"	"9.8"	"15.1"	"20.8"	"49.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P10619"	"Lysosomal protective protein OS=Homo sapiens OX=9606 GN=CTSA PE=1 SV=2"	"2"	"1"	"2"	"1"	"480"	"54.4"	"6.61"	"297.40"	"2.19"	"1"	"1"	"protein metabolism;transport;other biological processes"	"non-structural extracellular;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00450"	"5476"	"ENSG00000064601"	"CTSA"	"B2R798; hsa:5476; P10619; Q561W6; Q5JZH1; Q96KJ2; Q9BR08; Q9BW68"	"Ciliary landscape"	"MHC class II antigen presentation; Neutrophil degranulation; Glycosphingolipid metabolism; Sialic acid metabolism; Defective NEU1 causes sialidosis"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P25490"	"Transcriptional repressor protein YY1 OS=Homo sapiens OX=9606 GN=YY1 PE=1 SV=2"	"6"	"2"	"3"	"2"	"414"	"44.7"	"6.25"	"762.81"	"2.19"	"2"	"1"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00096"	"7528"	"ENSG00000100811"	"YY1"	"hsa:7528; P25490; Q14935"	"Sterol regulatory element-binding proteins (SREBP) signaling; Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4); Pleural mesothelioma"	"Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; UCH proteinases; DNA Damage Recognition in GG-NER; TFAP2 (AP-2) family regulates transcription of growth factors and their receptors"	"8"	"0"	"128.7"	"200.4"	"230.0"	"88.7"	"212.5"	"100.6"	"320.3"	"240.3"	"492.7"	"748.4"	"913.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BT78"	"COP9 signalosome complex subunit 4 OS=Homo sapiens OX=9606 GN=COPS4 PE=1 SV=1"	"3"	"1"	"2"	"1"	"406"	"46.2"	"5.83"	"236.72"	"2.19"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf01399, Pf18420"	"51138"	"ENSG00000138663"	"COPS4"	"B3KN88; B3KST5; hsa:51138; Q561W7; Q9BT78; Q9NW31; Q9Y677"	"Ciliary landscape"	"Cargo recognition for clathrin-mediated endocytosis; Neddylation; Formation of TC-NER Pre-Incision Complex; DNA Damage Recognition in GG-NER; RHOBTB1 GTPase cycle"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UHG3"	"Prenylcysteine oxidase 1 OS=Homo sapiens OX=9606 GN=PCYOX1 PE=1 SV=3"	"2"	"1"	"2"	"1"	"505"	"56.6"	"6.18"	"239.63"	"2.19"	"1"	"1"	"protein metabolism;other metabolic processes;transport"	"non-structural extracellular;plasma membrane;other membranes;other cytoplasmic organelle"	"other molecular function"	"Pf07156, Pf13450"	"51449"	"ENSG00000116005"	"PCYOX1"	"B2RB14; B7Z9P8; hsa:51449; O94982; Q8N4N5; Q96QM8; Q9UHG3"	""	""	"0"	"0"	"6.9"	"19.7"	"19.0"	"5.3"	"13.5"	"8.0"	"10.3"	"6.0"	"7.5"	"18.6"	"20.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H1A4"	"Anaphase-promoting complex subunit 1 OS=Homo sapiens OX=9606 GN=ANAPC1 PE=1 SV=1"	"1"	"2"	"3"	"2"	"1944"	"216.4"	"6.30"	"257.33"	"2.19"	"1"	"2"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf12859, Pf18122, Pf19521, Pf20518"	"64682"	"ENSG00000153107"	"ANAPC1"	"hsa:64682; Q2M3H8; Q9BSE6; Q9H1A4; Q9H8D0"	"Cell cycle; 2q13 copy number variation syndrome"	"Senescence-Associated Secretory Phenotype (SASP); Separation of Sister Chromatids; Antigen processing: Ubiquitination & Proteasome degradation; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; CDK-mediated phosphorylation and removal of Cdc6; Autodegradation of Cdh1 by Cdh1:APC/C; Assembly of the pre-replicative complex; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of Cyclin B; Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase; Regulation of APC/C activators between G1/S and early anaphase; Phosphorylation of the APC/C; APC-Cdc20 mediated degradation of Nek2A; Transcriptional Regulation by VENTX; Aberrant regulation of mitotic exit in cancer due to RB1 defects"	"20"	"0"	"8.8"	"19.3"	"17.1"	"4.8"	"21.8"	"7.3"	"17.6"	"12.6"	"16.7"	"24.8"	"39.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P46379"	"Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1132"	"119.3"	"5.60"	"272.99"	"2.19"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;other membranes;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;translation activity;other molecular function"	"Pf00240, Pf12057"	"7917"	"ENSG00000096155; ENSG00000204463; ENSG00000227761; ENSG00000228760; ENSG00000229524; ENSG00000233348; ENSG00000234651"	"BAG6"	"A2ADJ7; A3KQ42; A3KQ44; A6NGY6; A6PWF7; B0UX84; B4DZ12; B4E3V4; E7EMZ4; F8VXY4; hsa:7917; O95874; P46379; Q5HYL9; Q5SQ35; Q5SQ36; Q5SQ37; Q5SQ41; Q5SRP8; Q5SRP9; Q5STC1; Q5STX1; Q5STX3; Q96SA6; Q9BCN4"	""	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NW64"	"Pre-mRNA-splicing factor RBM22 OS=Homo sapiens OX=9606 GN=RBM22 PE=1 SV=1"	"4"	"1"	"2"	"1"	"420"	"46.9"	"8.54"	"324.58"	"2.19"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"55696"	"ENSG00000086589"	"RBM22"	"A6NDM5; B4DLI9; hsa:55696; O95607; Q9NW64"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"15.6"	"52.0"	"41.5"	"13.9"	"36.0"	"14.6"	"33.7"	"25.6"	"52.0"	"71.0"	"84.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5T653"	"39S ribosomal protein L2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL2 PE=1 SV=2"	"5"	"1"	"1"	"1"	"305"	"33.3"	"11.30"	""	"2.18"	""	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf00181, Pf03947"	"51069"	"ENSG00000112651"	"MRPL2"	"B2RC56; hsa:51069; Q5T653; Q8WUL1; Q96Q56; Q9Y311"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"n/a"	"n/a"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y296"	"Trafficking protein particle complex subunit 4 OS=Homo sapiens OX=9606 GN=TRAPPC4 PE=1 SV=1"	"4"	"1"	"2"	"1"	"219"	"24.3"	"6.21"	"276.98"	"2.18"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf04099"	"51399"	"ENSG00000196655; ENSG00000280495"	"TRAPPC4"	"A8K3A5; B4DME1; hsa:51399; Q9Y296"	""	"RAB GEFs exchange GTP for GDP on RABs; COPII-mediated vesicle transport; Syndecan interactions"	"3"	"0"	"13.6"	"38.0"	"33.9"	"13.5"	"29.5"	"13.1"	"30.7"	"33.0"	"46.3"	"62.2"	"108.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96ES7"	"SAGA-associated factor 29 OS=Homo sapiens OX=9606 GN=SGF29 PE=1 SV=1"	"4"	"1"	"2"	"1"	"293"	"33.2"	"8.10"	"241.75"	"2.18"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf07039"	"112869"	"ENSG00000176476"	"SGF29"	"hsa:112869; Q96ES7; Q96MF5"	""	"HATs acetylate histones; Formation of WDR5-containing histone-modifying complexes"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q04721"	"Neurogenic locus notch homolog protein 2 OS=Homo sapiens OX=9606 GN=NOTCH2 PE=1 SV=3"	"1"	"1"	"2"	"1"	"2471"	"265.2"	"5.14"	"236.03"	"2.18"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00008, Pf00066, Pf06816, Pf07645, Pf07684, Pf12661, Pf12796"	"4853"	"ENSG00000134250"	"NOTCH2"	"hsa:4853; Q04721; Q5T3X7; Q99734; Q9H240"	"Neural crest differentiation; Notch signaling; Canonical and non-canonical Notch signaling; OSX and miRNAs in tooth development; Epithelial to mesenchymal transition in colorectal cancer; Breast cancer pathway; Head and neck squamous cell carcinoma; Osteoblast differentiation and related diseases; Genes controlling nephrogenesis; Primary ovarian insufficiency; Notch signaling pathway"	"NOTCH2 Activation and Transmission of Signal to the Nucleus; Pre-NOTCH Processing in Golgi; Pre-NOTCH Transcription and Translation; Notch-HLH transcription pathway; NOTCH2 intracellular domain regulates transcription; NOTCH4 Intracellular Domain Regulates Transcription; Pre-NOTCH Processing in the Endoplasmic Reticulum; Defective LFNG causes SCDO3"	"19"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P78559"	"Microtubule-associated protein 1A OS=Homo sapiens OX=9606 GN=MAP1A PE=1 SV=6"	"1"	"2"	"3"	"1"	"2803"	"305.3"	"4.92"	"257.26"	"2.18"	"1"	"2"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	""	"4130"	"ENSG00000166963"	"MAP1A"	"hsa:4130; O95643; P78559; Q12973; Q15882; Q9UJT4"	""	""	"0"	"0"	"12.2"	"25.0"	"25.3"	"7.9"	"15.1"	"10.7"	"22.6"	"11.5"	"21.1"	"17.9"	"23.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NEZ3"	"WD repeat-containing protein 19 OS=Homo sapiens OX=9606 GN=WDR19 PE=1 SV=2"	"1"	"1"	"1"	"1"	"1342"	"151.5"	"6.35"	""	"2.18"	""	"1"	"cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"cytoskeleton;other cell component"	""	"Pf15911"	"57728"	"ENSG00000157796"	"WDR19"	"B5MEF2; hsa:57728; Q8N5B4; Q8NEZ3; Q9H5S0; Q9HCD4"	"Intraflagellar transport proteins binding to dynein; Genes related to primary cilium development (based on CRISPR); Ciliopathies; Bardet-Biedl syndrome"	"Intraflagellar transport; Hedgehog 'off' state"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IWX8"	"Calcium homeostasis endoplasmic reticulum protein OS=Homo sapiens OX=9606 GN=CHERP PE=1 SV=3"	"1"	"1"	"2"	"1"	"916"	"103.6"	"9.04"	"251.69"	"2.18"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf01585, Pf01805, Pf04818"	"10523"	"ENSG00000085872"	"CHERP"	"hsa:10523; O00302; Q4G0Y5; Q8IWX8; Q8WU30; Q99492"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"169.2"	"189.6"	"192.1"	"149.0"	"235.3"	"177.4"	"203.7"	"158.8"	"239.8"	"262.6"	"317.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86W56"	"Poly(ADP-ribose) glycohydrolase OS=Homo sapiens OX=9606 GN=PARG PE=1 SV=1"	"3"	"2"	"2"	"2"	"976"	"111.0"	"6.43"	"237.70"	"2.18"	"1"	"1"	"DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf05028"	"670; 8505"	"ENSG00000227345"	"PARG"	"A5YBK3; B2RC24; B4DIU5; B4DYR4; hsa:8505; I6RUV3; Q6E4P6; Q6E4P7; Q7Z742; Q86W56; Q9Y4W7"	"10q11.21q11.23 copy number variation syndrome"	"POLB-Dependent Long Patch Base Excision Repair"	"2"	"0"	"12.0"	"35.6"	"33.0"	"13.8"	"26.8"	"7.9"	"24.2"	"29.0"	"34.3"	"48.8"	"98.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13615"	"Myotubularin-related protein 3 OS=Homo sapiens OX=9606 GN=MTMR3 PE=1 SV=3"	"1"	"1"	"1"	"1"	"1198"	"133.5"	"5.80"	""	"2.17"	""	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;other cell component"	"other molecular function"	"Pf01363, Pf06602"	"8897"	"ENSG00000100330"	"MTMR3"	"A5PL26; A7MD32; hsa:8897; Q13615; Q9NYN5; Q9NYN6; Q9UDX6; Q9UEG3"	""	"Synthesis of PIPs at the plasma membrane; Macroautophagy"	"2"	"0"	"28.9"	"40.5"	"41.0"	"18.3"	"36.9"	"22.2"	"39.2"	"34.8"	"45.1"	"49.1"	"54.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IXM3"	"39S ribosomal protein L41, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL41 PE=1 SV=1"	"12"	"2"	"2"	"2"	"137"	"15.4"	"9.57"	"308.69"	"2.17"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus;other cell component"	"other molecular function"	"Pf09809"	"64975"	"ENSG00000182154"	"MRPL41"	"hsa:64975; Q8IXM3; Q96Q49"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"95.9"	"192.4"	"169.0"	"82.2"	"180.2"	"93.6"	"137.8"	"113.5"	"130.3"	"201.3"	"286.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9C0D5"	"Protein TANC1 OS=Homo sapiens OX=9606 GN=TANC1 PE=1 SV=3"	"0"	"1"	"1"	"1"	"1861"	"202.1"	"8.32"	""	"2.17"	""	"1"	"cell organization and biogenesis;other biological processes"	"other cell component"	""	"Pf00023, Pf12796"	"85461"	"ENSG00000115183"	"TANC1"	"C9JD88; hsa:85461; Q49AI8; Q9C0D5"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62854"	"40S ribosomal protein S26 OS=Homo sapiens OX=9606 GN=RPS26 PE=1 SV=3"	"8"	"1"	"1"	"1"	"115"	"13.0"	"11.00"	""	"2.17"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01283"	"6231"	"ENSG00000197728"	"RPS26"	"hsa:6231; P02383; P62854; P70394; Q06722; Q3MHD8; Q6IRY4"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Peptide chain elongation; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9NVN8"	"Guanine nucleotide-binding protein-like 3-like protein OS=Homo sapiens OX=9606 GN=GNL3L PE=1 SV=1"	"1"	"1"	"1"	"1"	"582"	"65.5"	"8.44"	""	"2.17"	""	"1"	"other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf01926"	"54552"	"ENSG00000130119"	"GNL3L"	"hsa:54552; Q9NVN8"	""	""	"0"	"0"	"117.3"	"288.9"	"371.0"	"221.0"	"353.8"	"218.0"	"321.3"	"223.4"	"316.9"	"411.4"	"606.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14244"	"Ensconsin OS=Homo sapiens OX=9606 GN=MAP7 PE=1 SV=1"	"1"	"1"	"1"	"1"	"749"	"84.0"	"9.61"	""	"2.16"	""	"1"	"cell organization and biogenesis;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf05672"	"9053"	"ENSG00000135525"	"MAP7"	"B7Z290; B7Z400; B7Z5S7; B7Z9U7; C9JPS0; E9PCP3; F5H1E2; hsa:9053; Q14244; Q7Z6S0; Q8TAU5; Q9NY82; Q9NY83"	""	""	"0"	"0"	"34.0"	"105.6"	"97.8"	"39.5"	"90.4"	"44.5"	"162.2"	"128.7"	"172.4"	"247.8"	"277.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NS40"	"Potassium voltage-gated channel subfamily H member 7 OS=Homo sapiens OX=9606 GN=KCNH7 PE=2 SV=2"	"1"	"1"	"1"	"1"	"1196"	"134.9"	"7.65"	""	"2.16"	""	"1"	"transport;other biological processes"	"plasma membrane;other membranes"	"transporter activity;other molecular function"	"Pf00027, Pf00520, Pf13426"	"90134"	"ENSG00000184611"	"KCNH7"	"hsa:90134; Q53QU4; Q53TB7; Q53TP9; Q8IV15; Q9NS40"	""	"Voltage gated Potassium channels"	"1"	"0"	"90.3"	"287.8"	"86.0"	"60.1"	"58.6"	"44.9"	"155.2"	"477.4"	"252.3"	"314.9"	"615.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96P16"	"Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1"	"4"	"1"	"2"	"1"	"312"	"35.7"	"7.55"	"253.96"	"2.16"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf04818, Pf16566"	"55197"	"ENSG00000141425"	"RPRD1A"	"A8KA42; B2RBA3; hsa:55197; Q7Z5G8; Q96FY9; Q96P16; Q9NVL4"	""	"RNA polymerase II transcribes snRNA genes"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y608"	"Leucine-rich repeat flightless-interacting protein 2 OS=Homo sapiens OX=9606 GN=LRRFIP2 PE=1 SV=1"	"2"	"1"	"1"	"1"	"721"	"82.1"	"6.95"	""	"2.16"	""	"1"	"cell-cell signaling;signal transduction;other biological processes"	""	"other molecular function"	"Pf09738"	"9209"	"ENSG00000093167"	"LRRFIP2"	"A8K649; A8MXR0; B4DY63; hsa:9209; Q68CV3; Q9NXH5; Q9Y608"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P26885"	"Peptidyl-prolyl cis-trans isomerase FKBP2 OS=Homo sapiens OX=9606 GN=FKBP2 PE=1 SV=2"	"8"	"1"	"2"	"1"	"142"	"15.6"	"9.13"	"347.23"	"2.16"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf00254"	"2286"	"ENSG00000173486"	"FKBP2"	"hsa:2286; P26885; Q5BJH9; Q9BTS7"	"Complement system"	""	"1"	"0"	"21.6"	"69.5"	"66.7"	"20.8"	"53.6"	"21.7"	"43.0"	"39.4"	"64.5"	"80.9"	"148.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NSE4"	"Isoleucine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=IARS2 PE=1 SV=2"	"1"	"1"	"1"	"1"	"1012"	"113.7"	"7.20"	""	"2.16"	""	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00133, Pf06827, Pf08264"	"55699"	"ENSG00000067704"	"IARS2"	"B2RPG8; hsa:55699; Q1M2P9; Q6PI85; Q7L439; Q86WU9; Q96D91; Q9H9Q8; Q9NSE4; Q9NW42"	""	"Mitochondrial tRNA aminoacylation"	"1"	"0"	"4.6"	"43.3"	"31.7"	"3.7"	"36.6"	"7.4"	"7.8"	"8.3"	"9.6"	"17.5"	"41.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P60763"	"Ras-related C3 botulinum toxin substrate 3 OS=Homo sapiens OX=9606 GN=RAC3 PE=1 SV=1"	"3"	"1"	"1"	"1"	"192"	"21.4"	"8.15"	""	"2.16"	""	"1"	"cell-cell signaling;cell organization and biogenesis;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf00071"	"5881"	"ENSG00000169750"	"RAC3"	"hsa:5881; O14658; P60763; Q5U0M8"	"Integrin-mediated cell adhesion; RalA downstream regulated genes; Focal adhesion; MAPK signaling pathway; Microglia pathogen phagocytosis pathway; Chromosomal and microsatellite instability in colorectal cancer ; Ras signaling; Pancreatic adenocarcinoma pathway; Acute viral myocarditis; Regulation of actin cytoskeleton"	"RAC3 GTPase cycle; PCP/CE pathway"	"12"	"0"	"48.3"	"257.6"	"173.1"	"31.8"	"174.7"	"70.6"	"99.2"	"96.0"	"95.8"	"131.4"	"213.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43396"	"Thioredoxin-like protein 1 OS=Homo sapiens OX=9606 GN=TXNL1 PE=1 SV=3"	"4"	"1"	"2"	"1"	"289"	"32.2"	"4.96"	"240.83"	"2.16"	"1"	"1"	""	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00085, Pf06201"	"9352"	"ENSG00000091164"	"TXNL1"	"hsa:9352; O43396"	""	"RND2 GTPase cycle; RHOV GTPase cycle; RHOU GTPase cycle; RND3 GTPase cycle; RND1 GTPase cycle; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle"	"7"	"0"	"7.8"	"23.6"	"23.6"	"8.8"	"18.3"	"13.3"	"18.2"	"20.3"	"21.4"	"25.0"	"29.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P33316"	"Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=DUT PE=1 SV=4"	"5"	"1"	"1"	"1"	"252"	"26.5"	"9.36"	""	"2.16"	""	"1"	"DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;mitochondrion;nucleus"	"signal transduction activity or receptor binding;other molecular function"	"Pf00692"	"1854"	"ENSG00000128951"	"DUT"	"A8K650; B4DPR5; hsa:1854; O14785; P33316; Q16708; Q16860; Q6FHN1; Q6NSA3; Q96Q81"	"Pyrimidine metabolism"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P17568"	"NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 OS=Homo sapiens OX=9606 GN=NDUFB7 PE=1 SV=4"	"4"	"1"	"1"	"1"	"137"	"16.4"	"8.92"	""	"2.16"	""	"1"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf05676"	"4713"	"ENSG00000099795"	"NDUFB7"	"hsa:4713; P17568; Q6ICN9; Q9UI16"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"39.4"	"100.1"	"87.9"	"39.7"	"81.0"	"55.8"	"93.0"	"64.1"	"118.5"	"194.0"	"285.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WYQ5"	"Microprocessor complex subunit DGCR8 OS=Homo sapiens OX=9606 GN=DGCR8 PE=1 SV=1"	"1"	"1"	"1"	"1"	"773"	"86.0"	"5.95"	""	"2.15"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00035"	"54487"	"ENSG00000128191"	"DGCR8"	"B2R8G1; hsa:54487; Q6DCB2; Q6MZE9; Q6Y2L0; Q8WYQ5; Q96G39; Q96GP8; Q9H6L8; Q9H6T7; Q9NRW2"	"miRNA biogenesis; exRNA mechanism of action and biogenesis; DDX1 as a regulatory component of the Drosha microprocessor; 22q11.2 copy number variation syndrome"	"Transcriptional Regulation by MECP2; MicroRNA (miRNA) biogenesis"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86VH2"	"Kinesin-like protein KIF27 OS=Homo sapiens OX=9606 GN=KIF27 PE=1 SV=1"	"0"	"1"	"2"	"1"	"1401"	"160.2"	"7.28"	"239.89"	"2.15"	"1"	"1"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"non-structural extracellular;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225"	"55582"	"ENSG00000165115"	"KIF27"	"B2RTR8; hsa:55582; Q5T6W0; Q86VH0; Q86VH1; Q86VH2; Q9UF54"	""	"COPI-dependent Golgi-to-ER retrograde traffic; Kinesins"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H6T3"	"RNA polymerase II-associated protein 3 OS=Homo sapiens OX=9606 GN=RPAP3 PE=1 SV=2"	"2"	"1"	"3"	"1"	"665"	"75.7"	"6.84"	"240.92"	"2.15"	"1"	"1"	"other biological processes"	"cytosol;other cell component"	""	"Pf00515, Pf13176, Pf13181, Pf13877"	"79657"	"ENSG00000005175"	"RPAP3"	"B4DRW9; hsa:79657; Q6PHR5; Q9H6T3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BT40"	"Inositol polyphosphate 5-phosphatase K OS=Homo sapiens OX=9606 GN=INPP5K PE=1 SV=3"	"3"	"1"	"1"	"1"	"448"	"51.1"	"6.54"	""	"2.15"	""	"1"	"cell organization and biogenesis;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf03372, Pf17751"	"51763"	"ENSG00000132376"	"INPP5K"	"B2R6I2; B2R750; D3DTH8; hsa:51763; Q15733; Q9BT40; Q9NPJ5; Q9P2R5"	"Notch signaling; VEGFA-VEGFR2 signaling; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"Synthesis of PIPs at the plasma membrane"	"4"	"0"	"24.3"	"64.2"	"55.8"	"23.3"	"55.9"	"32.4"	"82.2"	"92.4"	"92.5"	"146.7"	"148.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y6B7"	"AP-4 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP4B1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"739"	"83.2"	"5.86"	"253.66"	"2.15"	"1"	"1"	"transport;other biological processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle"	"other molecular function"	"Pf01602, Pf09066"	"10717"	"ENSG00000134262"	"AP4B1"	"B7Z4X3; hsa:10717; Q59EJ4; Q96CL6; Q9Y6B7"	""	"Lysosome Vesicle Biogenesis; Golgi Associated Vesicle Biogenesis"	"2"	"0"	"275.6"	"326.3"	"437.5"	"287.8"	"404.5"	"380.3"	"176.4"	"91.9"	"157.0"	"246.2"	"489.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15357"	"Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 OS=Homo sapiens OX=9606 GN=INPPL1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1258"	"138.5"	"6.54"	"332.66"	"2.15"	"1"	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00017, Pf00536, Pf03372"	"3636"	"ENSG00000165458"	"INPPL1"	"B2RTX5; hsa:3636; O15357; Q13577; Q13578"	"EGF/EGFR signaling pathway; Insulin signaling"	"Synthesis of PIPs at the plasma membrane; Interleukin receptor SHC signaling; Synthesis of IP3 and IP4 in the cytosol; Signaling by CSF1 (M-CSF) in myeloid cells"	"6"	"0"	"5.0"	"34.4"	"26.0"	"7.9"	"27.7"	"6.5"	"18.5"	"11.6"	"13.1"	"26.5"	"58.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14677"	"Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1"	"2"	"1"	"1"	"1"	"625"	"68.2"	"6.42"	""	"2.15"	""	"1"	"transport"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01417"	"9685"	"ENSG00000113282"	"CLINT1"	"B7Z6F8; D3DQJ6; hsa:9685; Q14677; Q8NAF1; Q96E05"	""	"Golgi Associated Vesicle Biogenesis"	"1"	"0"	"63.1"	"326.8"	"265.2"	"59.8"	"246.2"	"74.3"	"79.6"	"67.2"	"116.1"	"170.8"	"294.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43913"	"Origin recognition complex subunit 5 OS=Homo sapiens OX=9606 GN=ORC5 PE=1 SV=1"	"2"	"1"	"1"	"1"	"435"	"50.3"	"7.74"	""	"2.14"	""	"1"	"DNA metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13191, Pf14630"	"5001"	"ENSG00000164815"	"ORC5"	"A4D0P8; hsa:5001; O43913; O60590; O95268"	"Cell cycle; G1 to S cell cycle control; DNA replication"	"Orc1 removal from chromatin; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; E2F-enabled inhibition of pre-replication complex formation; Assembly of the ORC complex at the origin of replication; CDC6 association with the ORC:origin complex"	"10"	"0"	"143.3"	"162.3"	"180.9"	"136.7"	"176.8"	"119.4"	"216.2"	"182.0"	"223.0"	"266.0"	"341.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13356"	"RING-type E3 ubiquitin-protein ligase PPIL2 OS=Homo sapiens OX=9606 GN=PPIL2 PE=1 SV=1"	"2"	"1"	"1"	"1"	"520"	"58.8"	"8.78"	""	"2.14"	""	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00160"	"23759"	"ENSG00000100023"	"PPIL2"	"hsa:23759; Q13356; Q13357; Q8TAH2; Q9BWR8"	""	"mRNA Splicing - Major Pathway; Basigin interactions"	"2"	"0"	"6.4"	"7.9"	"9.7"	"8.4"	"9.3"	"6.3"	"19.7"	"18.1"	"23.4"	"27.1"	"31.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q03113"	"Guanine nucleotide-binding protein subunit alpha-12 OS=Homo sapiens OX=9606 GN=GNA12 PE=1 SV=4"	"2"	"1"	"1"	"1"	"381"	"44.3"	"9.83"	""	"2.14"	""	"1"	"stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00503"	"2768"	"ENSG00000146535"	"GNA12"	"A4D204; B3KXS2; B7Z3F7; hsa:2768; Q03113; Q2T9L1; Q5PPR5; Q86UM8; Q8TD71; Q9UDU9"	"Thyroid stimulating hormone (TSH) signaling pathway; G protein signaling pathways; MAPK signaling pathway; Opioid receptor pathways; Regulation of actin cytoskeleton"	"G alpha (12/13) signalling events; Thrombin signalling through proteinase activated receptors (PARs)"	"7"	"0"	"16.5"	"46.4"	"30.9"	"14.6"	"28.0"	"13.9"	"33.3"	"29.4"	"40.9"	"60.2"	"76.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UKX2"	"Myosin-2 OS=Homo sapiens OX=9606 GN=MYH2 PE=1 SV=1"	"1"	"1"	"1"	"1"	"1941"	"222.9"	"5.82"	""	"2.14"	""	"1"	"other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00063, Pf01576, Pf02736"	"4620"	"ENSG00000125414"	"MYH2"	"A0AVL4; hsa:4620; Q14322; Q16229; Q567P6; Q86T56; Q9UKX2"	""	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis"	"2"	"0"	"6.2"	"11.8"	"13.7"	"9.1"	"16.8"	"8.6"	"9.3"	"6.1"	"24.3"	"41.9"	"55.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P06730"	"Eukaryotic translation initiation factor 4E OS=Homo sapiens OX=9606 GN=EIF4E PE=1 SV=2"	"3"	"1"	"2"	"1"	"217"	"25.1"	"6.15"	"310.52"	"2.14"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01652"	"1977"	"ENSG00000151247"	"EIF4E"	"B7Z6V1; D6RCQ6; hsa:1977; P06730; Q96E95"	"Translation factors; Leptin signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Interleukin-1 (IL-1) structural pathway; Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4); Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; 4-hydroxytamoxifen, dexamethasone, and retinoic acids regulation of p27 expression; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Head and neck squamous cell carcinoma; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; Host-pathogen interaction of human coronaviruses - MAPK signaling; Hypertrophy model; Interferon type I signaling pathways"	"Deadenylation of mRNA; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; mTORC1-mediated signalling"	"30"	"0"	"120.6"	"286.4"	"239.7"	"94.5"	"224.8"	"118.3"	"172.8"	"133.1"	"184.6"	"237.1"	"530.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14923"	"Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3"	"3"	"3"	"4"	"3"	"745"	"81.7"	"6.14"	"746.16"	"2.14"	"3"	"1"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;RNA metabolism OR transcription;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00514"	"3728"	"ENSG00000173801"	"JUP"	"hsa:3728; P14923; Q15093; Q15151; Q7L3S5; Q86W21; Q9BWC4; Q9HCX9"	"Arrhythmogenic right ventricular cardiomyopathy; Corticotropin-releasing hormone signaling pathway; Ectoderm differentiation; Ectoderm differentiation; Epithelial to mesenchymal transition in colorectal cancer; Opioid receptor pathways"	"Neutrophil degranulation; Formation of the cornified envelope; RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RHOQ GTPase cycle; RHOB GTPase cycle; RHOJ GTPase cycle; VEGFR2 mediated vascular permeability; Adherens junctions interactions; Regulation of CDH11 function; Regulation of CDH19 Expression and Function; CDH11 homotypic and heterotypic interactions; RHOH GTPase cycle"	"21"	"0"	"16.0"	"54.0"	"221.0"	"15.9"	"14.5"	"21.3"	"30.9"	"36.9"	"42.5"	"43.8"	"42.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P56134"	"ATP synthase subunit f, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5MF PE=1 SV=3"	"12"	"1"	"2"	"1"	"94"	"10.9"	"9.67"	"295.71"	"2.14"	"1"	"1"	"other metabolic processes;transport"	"other membranes;mitochondrion;nucleus"	""	"Pf10206"	"9551"	"ENSG00000241468"	"ATP5MF"	"C9J8H9; F8W7V3; hsa:9551; O76079; P56134; Q6IBB3; Q96L83; Q9BTI8"	"Electron transport chain: OXPHOS system in mitochondria; Oxidative phosphorylation"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"4"	"0"	"15.5"	"55.5"	"54.0"	"11.3"	"49.3"	"22.0"	"32.1"	"24.2"	"39.5"	"54.1"	"78.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H2D6"	"TRIO and F-actin-binding protein OS=Homo sapiens OX=9606 GN=TRIOBP PE=1 SV=3"	"0"	"1"	"1"	"1"	"2365"	"261.2"	"8.48"	""	"2.14"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00169"	"11078"	"ENSG00000100106"	"TRIOBP"	"B1AHD4; B1AHD7; F2Z2W0; F8W6V6; hsa:11078; O94797; Q2PZW8; Q2Q3Z9; Q2Q400; Q5R3M6; Q96DW1; Q9BT77; Q9BTL7; Q9BY98; Q9H2D6; Q9Y3L4"	""	""	"0"	"0"	"95.7"	"185.0"	"187.8"	"67.3"	"165.8"	"103.4"	"227.8"	"161.3"	"239.6"	"310.9"	"479.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y4C2"	"TRPM8 channel-associated factor 1 OS=Homo sapiens OX=9606 GN=TCAF1 PE=1 SV=3"	"1"	"1"	"1"	"1"	"921"	"102.1"	"6.54"	""	"2.14"	""	"1"	"other biological processes"	"plasma membrane;other membranes"	"other molecular function"	"Pf13402, Pf17291"	"9747"	"ENSG00000198420"	"TCAF1"	"A8K6E0; hsa:9747; Q75KM8; Q75KM9; Q7L665; Q9BW63; Q9Y4C2"	""	""	"0"	"0"	"12.0"	"26.1"	"31.3"	"10.0"	"24.9"	"13.9"	"29.9"	"27.6"	"35.4"	"49.2"	"78.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95985"	"DNA topoisomerase 3-beta-1 OS=Homo sapiens OX=9606 GN=TOP3B PE=1 SV=1"	"1"	"1"	"1"	"1"	"862"	"96.6"	"8.12"	""	"2.14"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01131, Pf01751"	"8940"	"ENSG00000100038"	"TOP3B"	"A0M8Q3; hsa:8940; O95985; Q9BUP5"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8WZA0"	"Protein LZIC OS=Homo sapiens OX=9606 GN=LZIC PE=1 SV=1"	"6"	"1"	"1"	"1"	"190"	"21.5"	"4.94"	""	"2.14"	""	"1"	"other biological processes"	""	"other molecular function"	"Pf06384"	"84328"	"ENSG00000162441"	"LZIC"	"B2R6F0; B4E2N0; hsa:84328; Q8WZA0; Q96IU1"	""	""	"0"	"0"	"6.6"	"16.6"	"13.2"	"2.0"	"13.9"	"6.4"	"10.0"	"6.6"	"11.6"	"16.5"	"22.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O96008"	"Mitochondrial import receptor subunit TOM40 homolog OS=Homo sapiens OX=9606 GN=TOMM40 PE=1 SV=1"	"3"	"1"	"2"	"1"	"361"	"37.9"	"7.25"	"249.88"	"2.14"	"1"	"1"	"cell organization and biogenesis;transport"	"other membranes;cytosol;mitochondrion;other cell component"	"transporter activity"	"Pf01459"	"10452"	"ENSG00000130204"	"TOMM40"	"A0A024R0P9; hsa:10452; O96008; Q86VW4; Q8WY09; Q8WY10; Q8WY11; Q9BR95"	"IL-18 signaling pathway"	"Mitochondrial protein import; PINK1-PRKN Mediated Mitophagy"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14C86"	"GTPase-activating protein and VPS9 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=GAPVD1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1478"	"164.9"	"5.22"	"240.27"	"2.13"	"1"	"1"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00616, Pf02204, Pf18151"	"26130"	"ENSG00000165219"	"GAPVD1"	"A8MYK3; B0QZ62; B0QZ63; B0QZ64; hsa:26130; Q14C76; Q14C86; Q2Q1W1; Q8ND92; Q8WU86; Q96CZ4; Q9NXQ1; Q9P207; Q9Y4N0"	""	"RAB GEFs exchange GTP for GDP on RABs; Clathrin-mediated endocytosis"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A6NC98"	"Coiled-coil domain-containing protein 88B OS=Homo sapiens OX=9606 GN=CCDC88B PE=1 SV=1"	"1"	"1"	"2"	"1"	"1476"	"164.7"	"5.11"	""	"2.13"	""	"1"	"cell organization and biogenesis;stress response;transport;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf19047"	"283234"	"ENSG00000168071"	"CCDC88B"	"A5D8Y5; A6NC98; B5MDM2; hsa:283234; Q05BL2; Q6RUV3; Q8N1Q6; Q8NF44; Q9H0H1"	""	""	"0"	"0"	"8.5"	"23.1"	"22.6"	"6.7"	"25.9"	"14.8"	"16.5"	"6.0"	"11.9"	"22.0"	"31.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08195"	"4F2 cell-surface antigen heavy chain OS=Homo sapiens OX=9606 GN=SLC3A2 PE=1 SV=3"	"2"	"1"	"1"	"1"	"630"	"68.0"	"5.01"	""	"2.13"	""	"1"	"other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;nucleus;other cytoplasmic organelle;other cell component"	"transporter activity;nucleic acid binding activity"	"Pf00128, Pf16028"	"6520"	"ENSG00000168003"	"SLC3A2"	"hsa:6520; J3KPF3; P08195; Q13543"	"mRNA, protein, and metabolite inducation pathway by cyclosporin A; Ferroptosis; Proximal tubule transport; Pleural mesothelioma"	"Tryptophan catabolism; Basigin interactions; Amino acid transport across the plasma membrane; Defective SLC7A7 causes lysinuric protein intolerance (LPI)"	"8"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NX63"	"MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1"	"5"	"1"	"1"	"1"	"227"	"26.1"	"8.28"	""	"2.12"	""	"1"	"cell organization and biogenesis"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf05300"	"54927"	"ENSG00000106554"	"CHCHD3"	"hsa:54927; Q9NX63"	""	"Cristae formation; Mitochondrial protein import"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UF33"	"Ephrin type-A receptor 6 OS=Homo sapiens OX=9606 GN=EPHA6 PE=2 SV=3"	"1"	"1"	"1"	"1"	"1036"	"116.3"	"6.98"	""	"2.12"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction"	"plasma membrane;other membranes;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00041, Pf00536, Pf01404, Pf07699, Pf07714, Pf14575"	"285220"	"ENSG00000080224"	"EPHA6"	"D6RAL5; hsa:285220; Q9UF33"	""	"EPH-ephrin mediated repulsion of cells; EPHA-mediated growth cone collapse"	"3"	"0"	"80.4"	"83.4"	"97.6"	"75.7"	"104.7"	"81.3"	"109.8"	"91.6"	"107.7"	"148.9"	"141.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q01954"	"Zinc finger protein basonuclin-1 OS=Homo sapiens OX=9606 GN=BNC1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"994"	"110.9"	"7.36"	""	"2.12"	""	"1"	"RNA metabolism OR transcription;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00096, Pf12874"	"646"	"ENSG00000169594"	"BNC1"	"hsa:646; Q01954; Q15840"	"Primary ovarian insufficiency"	""	"1"	"0"	"143.2"	"316.7"	"403.9"	"163.2"	"357.9"	"188.0"	"232.9"	"138.4"	"228.2"	"230.6"	"331.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14498"	"RNA-binding protein 39 OS=Homo sapiens OX=9606 GN=RBM39 PE=1 SV=2"	"2"	"1"	"1"	"1"	"530"	"59.3"	"10.10"	""	"2.12"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00076, Pf15519"	"9584"	"ENSG00000131051"	"RBM39"	"A2RRD3; A5D8W2; B0BLV3; E1P5S0; E1P5S1; hsa:9584; Q14498; Q14499"	"VEGFA-VEGFR2 signaling; mRNA processing"	"mRNA Splicing - Major Pathway"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43665"	"Regulator of G-protein signaling 10 OS=Homo sapiens OX=9606 GN=RGS10 PE=1 SV=3"	"6"	"1"	"2"	"1"	"181"	"21.2"	"7.49"	"240.22"	"2.12"	"1"	"1"	"cell-cell signaling;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00615"	"6001"	"ENSG00000148908"	"RGS10"	"A8K408; B1AMR8; hsa:6001; O43665; Q6IAZ6; Q96GN0"	"Mesodermal commitment pathway; Myometrial relaxation and contraction pathways; Calcium regulation in cardiac cells"	"G alpha (i) signalling events"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92574"	"Hamartin OS=Homo sapiens OX=9606 GN=TSC1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"1164"	"129.7"	"6.47"	"320.61"	"2.11"	"1"	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf04388"	"7248"	"ENSG00000165699"	"TSC1"	"B7Z897; hsa:7248; Q5VVN5; Q92574"	"AMP-activated protein kinase signaling; Target of rapamycin signaling; Glioblastoma signaling pathways; Nanoparticle triggered autophagic cell death; Wnt signaling pathway; BDNF-TrkB signaling; 4-hydroxytamoxifen, dexamethasone, and retinoic acids regulation of p27 expression; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Clear cell renal cell carcinoma pathways; PI3K/AKT/mTOR - vitamin D3 signaling; PI3K-Akt signaling pathway; Thermogenesis; Synaptic signaling pathways associated with autism spectrum disorder; Fragile X syndrome; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Head and neck squamous cell carcinoma; Thyroid hormones production and peripheral downstream signaling effects; Insulin signaling; CAMKK2 pathway; Pleural mesothelioma; DYRK1A involvement regarding cell proliferation in brain development"	"TP53 Regulates Metabolic Genes; Macroautophagy; Energy dependent regulation of mTOR by LKB1-AMPK; TBC/RABGAPs; Inhibition of TSC complex formation by PKB"	"27"	"0"	"12.9"	"34.5"	"41.5"	"10.9"	"30.2"	"16.4"	"21.0"	"11.3"	"22.7"	"28.3"	"36.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96RP7"	"Galactose-3-O-sulfotransferase 4 OS=Homo sapiens OX=9606 GN=GAL3ST4 PE=1 SV=1"	"5"	"1"	"1"	"1"	"486"	"54.1"	"10.18"	""	"2.11"	""	"1"	"cell-cell signaling;protein metabolism;other metabolic processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf06990"	"79690"	"ENSG00000197093"	"GAL3ST4"	"A4D2A8; B4DWL8; D6W5U5; hsa:79690; Q8N3P7; Q8WZ17; Q96E33; Q96RP7; Q9HA78"	"TYROBP causal network in microglia; Metapathway biotransformation Phase I and II"	""	"2"	"0"	"253.0"	"187.9"	"228.3"	"214.7"	"257.7"	"287.8"	"407.6"	"327.1"	"356.4"	"376.0"	"402.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NHP8"	"Putative phospholipase B-like 2 OS=Homo sapiens OX=9606 GN=PLBD2 PE=1 SV=2"	"3"	"1"	"1"	"1"	"589"	"65.4"	"6.80"	""	"2.11"	""	"1"	"other metabolic processes"	"non-structural extracellular;other cytoplasmic organelle"	"other molecular function"	"Pf04916"	"196463"	"ENSG00000151176"	"PLBD2"	"F5H5E2; hsa:196463; Q8NHP8"	""	""	"0"	"0"	"121.4"	"119.9"	"135.9"	"98.1"	"121.0"	"101.4"	"212.7"	"177.8"	"223.9"	"262.6"	"305.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NS86"	"LanC-like protein 2 OS=Homo sapiens OX=9606 GN=LANCL2 PE=1 SV=1"	"2"	"1"	"2"	"1"	"450"	"50.8"	"7.43"	"252.34"	"2.10"	"1"	"1"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus"	"other molecular function"	"Pf05147"	"55915"	"ENSG00000132434"	"LANCL2"	"B2R8D4; hsa:55915; Q6NSL4; Q8TCQ3; Q9BSR1; Q9NS86"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75438"	"NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 OS=Homo sapiens OX=9606 GN=NDUFB1 PE=1 SV=1"	"19"	"1"	"1"	"1"	"58"	"7.0"	"8.92"	""	"2.10"	""	"1"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion;nucleus"	"transporter activity"	"Pf08040"	"4707"	"ENSG00000183648"	"NDUFB1"	"A0AV68; hsa:4707; O75438"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q09161"	"Nuclear cap-binding protein subunit 1 OS=Homo sapiens OX=9606 GN=NCBP1 PE=1 SV=1"	"1"	"1"	"2"	"1"	"790"	"91.8"	"6.43"	"292.19"	"2.10"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02854, Pf09088, Pf09090"	"4686"	"ENSG00000136937"	"NCBP1"	"B2R718; hsa:4686; Q09161; Q59G76; Q5T1V0; Q5T7X2"	"mRNA processing; 3q29 copy number variation syndrome"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Abortive elongation of HIV-1 transcript in the absence of Tat; RNA Polymerase II Pre-transcription Events; RNA polymerase II transcribes snRNA genes; mRNA Capping; mRNA Splicing - Major Pathway; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Signaling by FGFR2 IIIa TM; Regulation of expression of SLITs and ROBOs; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; snRNP Assembly; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Processing of Intronless Pre-mRNAs; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"29"	"0"	"13.3"	"39.4"	"42.3"	"19.9"	"35.8"	"21.7"	"29.7"	"25.1"	"37.4"	"48.4"	"64.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60299"	"Leucine zipper putative tumor suppressor 3 OS=Homo sapiens OX=9606 GN=LZTS3 PE=2 SV=1"	"1"	"1"	"1"	"1"	"673"	"71.7"	"7.64"	""	"2.10"	""	"1"	"other biological processes"	"cytoskeleton;other cell component"	""	"Pf06818"	"9762"	"ENSG00000088899"	"LZTS3"	"A2A2Q7; D3DVX6; hsa:9762; O60299; Q8IXX8"	""	""	"0"	"0"	"33.7"	"95.4"	"91.0"	"34.2"	"87.9"	"43.5"	"70.9"	"58.9"	"79.2"	"85.2"	"119.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UN81"	"LINE-1 retrotransposable element ORF1 protein OS=Homo sapiens OX=9606 GN=L1RE1 PE=1 SV=1"	"3"	"1"	"1"	"1"	"338"	"40.0"	"9.51"	""	"2.09"	""	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02994, Pf17489, Pf17490"	""	""	"L1RE1"	"Q15605; Q9UN81"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q07889"	"Son of sevenless homolog 1 OS=Homo sapiens OX=9606 GN=SOS1 PE=1 SV=1"	"1"	"2"	"2"	"2"	"1333"	"152.4"	"6.84"	"243.66"	"2.09"	"1"	"1"	"cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00169, Pf00617, Pf00618, Pf00621"	"6654"	"ENSG00000115904"	"SOS1"	"A8K2G3; B4DXG2; hsa:6654; Q07889"	"IL-5 signaling pathway; Integrin-mediated cell adhesion; Leptin signaling pathway; Prolactin signaling pathway; Pilocytic astrocytoma; Androgen receptor network in prostate cancer; B cell receptor signaling pathway; TNF-alpha signaling pathway; Oncostatin M signaling pathway; Alpha 6 beta 4 signaling pathway; IL-3 signaling pathway; Kit receptor signaling pathway; Focal adhesion; Hepatocyte growth factor receptor signaling; RAC1/PAK1/p38/MMP2 pathway; IL6 signaling pathway; Hepatitis C and hepatocellular carcinoma; BDNF-TrkB signaling; Physico-chemical features and toxicity-associated pathways; MAPK signaling pathway; T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection; Angiopoietin-like protein 8 regulatory pathway; Chemokine signaling pathway; Embryonic stem cell pluripotency pathways; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; IL-4 signaling pathway; Endometrial cancer; PI3K-Akt signaling pathway; MAPK cascade; Ras signaling; Epithelial to mesenchymal transition in colorectal cancer; Non-small cell lung cancer; Breast cancer pathway; Acute viral myocarditis; Thermogenesis; EGF/EGFR signaling pathway; Envelope proteins and their potential roles in EDMD physiopathology; Fragile X syndrome; Gastrin signaling pathway; Hepatitis B infection; Melanoma; Thyroid hormones production and peripheral downstream signaling effects; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; IL-2 signaling pathway; MAPK pathway in congenital thyroid cancer; Pleural mesothelioma; Regulation of actin cytoskeleton; EPO receptor signaling; ErbB signaling pathway; T-cell receptor signaling pathway; DNA damage response (only ATM dependent)"	"RAC1 GTPase cycle; Role of LAT2/NTAL/LAB on calcium mobilization; RET signaling; Downstream signal transduction; Tie2 Signaling; Signaling by CSF1 (M-CSF) in myeloid cells; FRS-mediated FGFR1 signaling; FRS-mediated FGFR2 signaling; FRS-mediated FGFR3 signaling; FRS-mediated FGFR4 signaling; FLT3 Signaling; Activated NTRK2 signals through FRS2 and FRS3; Signaling by FLT3 ITD and TKD mutants; FCERI mediated MAPK activation; FCERI mediated Ca+2 mobilization; Potential therapeutics for SARS; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; NRAGE signals death through JNK; G alpha (12/13) signalling events; Interleukin receptor SHC signaling; RAF/MAP kinase cascade; DAP12 signaling; Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants; Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants; Signaling by PDGFRA extracellular domain mutants; Regulation of KIT signaling; SHC1 events in ERBB2 signaling; SHC1 events in ERBB4 signaling; GRB2 events in ERBB2 signaling; Signaling by ERBB2 KD Mutants; Signaling by ERBB2 TMD/JMD mutants; GRB2 events in EGFR signaling; SHC1 events in EGFR signaling; NCAM signaling for neurite out-growth; Signaling by FGFR1 in disease; SHC-mediated cascade:FGFR1; SHC-mediated cascade:FGFR2; Signaling by FGFR2 in disease; SHC-mediated cascade:FGFR3; SHC-mediated cascade:FGFR4; Signaling by FGFR3 in disease; Activation of RAC1; Erythropoietin activates RAS; Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; EGFR Transactivation by Gastrin; Constitutive Signaling by EGFRvIII; Signaling by ERBB2 ECD mutants; SOS-mediated signalling; Signalling to RAS; SHC-related events triggered by IGF1R; Signaling by FGFR4 in disease; MET activates RAS signaling; Activated NTRK2 signals through RAS; Activated NTRK3 signals through RAS; Constitutive Signaling by Overexpressed ERBB2; Signaling by FLT3 fusion proteins; Signal attenuation; GRB2:SOS provides linkage to MAPK signaling for Integrins ; Interleukin-15 signaling"	"113"	"0"	"74.2"	"226.3"	"214.8"	"87.9"	"187.7"	"91.6"	"163.8"	"159.4"	"307.2"	"516.2"	"880.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5VV42"	"Threonylcarbamoyladenosine tRNA methylthiotransferase OS=Homo sapiens OX=9606 GN=CDKAL1 PE=1 SV=1"	"2"	"1"	"1"	"1"	"579"	"65.1"	"7.46"	""	"2.09"	""	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf00919, Pf01938, Pf04055"	"54901"	"ENSG00000145996"	"CDKAL1"	"A8K6S0; hsa:54901; Q5VV42; Q6P385; Q6ZR27; Q9NXB3"	"Vitamin D receptor pathway"	"tRNA modification in the nucleus and cytosol"	"2"	"0"	"4.6"	"17.7"	"16.1"	"3.4"	"14.6"	"4.6"	"12.2"	"10.2"	"11.4"	"21.4"	"32.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQE4"	"Selenoprotein S OS=Homo sapiens OX=9606 GN=SELENOS PE=1 SV=3"	"6"	"1"	"1"	"1"	"189"	"21.2"	"9.70"	""	"2.09"	""	"1"	"protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytoskeleton;ER/Golgi"	"other molecular function"	"Pf06936"	"55829"	"ENSG00000131871"	"SELENOS"	"hsa:55829; Q3B771; Q9BQE4; Q9P0I6"	"Selenium micronutrient network"	"E3 ubiquitin ligases ubiquitinate target proteins"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P24539"	"ATP synthase F(0) complex subunit B1, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PB PE=1 SV=2"	"5"	"1"	"1"	"1"	"256"	"28.9"	"9.36"	""	"2.09"	""	"1"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf05405"	"515"	"ENSG00000116459"	"ATP5PB"	"hsa:515; P24539; Q9BQ68; Q9BRU8"	"Electron transport chain: OXPHOS system in mitochondria; 7q11.23 copy number variation syndrome; Oxidative phosphorylation"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"5"	"0"	"38.4"	"43.6"	"114.1"	"29.3"	"31.9"	"32.7"	"57.9"	"50.0"	"63.3"	"66.7"	"85.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NPB8"	"Glycerophosphocholine phosphodiesterase GPCPD1 OS=Homo sapiens OX=9606 GN=GPCPD1 PE=1 SV=2"	"3"	"1"	"1"	"1"	"672"	"76.0"	"5.53"	""	"2.09"	""	"1"	"other metabolic processes;other biological processes"	"cytosol"	"other molecular function"	"Pf00686, Pf03009"	"56261"	"ENSG00000125772"	"GPCPD1"	"D3DW06; hsa:56261; Q9BQL8; Q9NPB8; Q9NUX0"	""	"Hydrolysis of LPC; Hydrolysis of LPE"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N392"	"Rho GTPase-activating protein 18 OS=Homo sapiens OX=9606 GN=ARHGAP18 PE=1 SV=3"	"2"	"1"	"1"	"1"	"663"	"74.9"	"6.44"	""	"2.08"	""	"1"	"cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity"	"Pf00620"	"93663"	"ENSG00000146376"	"ARHGAP18"	"E1P575; hsa:93663; Q58EZ3; Q6P679; Q6PJD7; Q8N392; Q96S64"	""	"RHOA GTPase cycle; RHOC GTPase cycle"	"2"	"0"	"3.5"	"18.0"	"18.3"	"6.0"	"15.6"	"5.4"	"16.6"	"8.1"	"16.4"	"37.3"	"54.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UJX4"	"Anaphase-promoting complex subunit 5 OS=Homo sapiens OX=9606 GN=ANAPC5 PE=1 SV=2"	"2"	"1"	"1"	"1"	"755"	"85.0"	"6.87"	""	"2.08"	""	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus"	"other molecular function"	"Pf12862"	"51433"	"ENSG00000089053"	"ANAPC5"	"E9PFB2; hsa:51433; Q8N4H7; Q9BQD4; Q9UJX4"	"Cell cycle"	"Separation of Sister Chromatids; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; CDK-mediated phosphorylation and removal of Cdc6; Regulation of APC/C activators between G1/S and early anaphase; Senescence-Associated Secretory Phenotype (SASP); Antigen processing: Ubiquitination & Proteasome degradation; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Autodegradation of Cdh1 by Cdh1:APC/C; Assembly of the pre-replicative complex; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of Cyclin B; Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase; Phosphorylation of the APC/C; APC-Cdc20 mediated degradation of Nek2A; Transcriptional Regulation by VENTX; Aberrant regulation of mitotic exit in cancer due to RB1 defects"	"19"	"0"	"181.6"	"393.7"	"438.8"	"184.2"	"395.4"	"224.2"	"479.9"	"313.8"	"527.3"	"548.4"	"801.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A6PVS8"	"Leucine-rich repeat and IQ domain-containing protein 3 OS=Homo sapiens OX=9606 GN=LRRIQ3 PE=1 SV=1"	"2"	"1"	"1"	"1"	"624"	"73.6"	"9.72"	""	"2.08"	""	"1"	""	""	""	"Pf12799"	"127255"	"ENSG00000162620"	"LRRIQ3"	"A6PVS8; A6PVS9; hsa:127255; Q6P5P7; Q6ZMV4; Q8WUE0"	""	""	"0"	"0"	"174.0"	"150.0"	"179.3"	"138.9"	"195.7"	"158.5"	"256.2"	"233.8"	"272.2"	"334.1"	"392.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96SN8"	"CDK5 regulatory subunit-associated protein 2 OS=Homo sapiens OX=9606 GN=CDK5RAP2 PE=1 SV=5"	"0"	"1"	"1"	"1"	"1893"	"214.9"	"5.58"	""	"2.08"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf07989"	"55755"	"ENSG00000136861"	"CDK5RAP2"	"hsa:55755; Q5JV18; Q7Z3L4; Q7Z3U1; Q7Z7I6; Q96SN8; Q9BSW0; Q9H6J6; Q9HCD9; Q9NV90; Q9UIW9"	""	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"7"	"0"	"63.9"	"180.5"	"172.5"	"57.3"	"139.7"	"63.8"	"106.8"	"89.5"	"113.3"	"197.8"	"340.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NTI5"	"Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens OX=9606 GN=PDS5B PE=1 SV=1"	"1"	"1"	"1"	"1"	"1447"	"164.6"	"8.47"	""	"2.08"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf20168"	"23047"	"ENSG00000083642"	"PDS5B"	"hsa:23047; Q5R3S3; Q5W0K8; Q6NSC3; Q8IXT6; Q9H5N8; Q9NTI5; Q9Y2I5; Q9Y451"	"Cohesin complex - Cornelia de Lange syndrome"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2H6"	"Fibronectin type-III domain-containing protein 3A OS=Homo sapiens OX=9606 GN=FNDC3A PE=1 SV=4"	"1"	"1"	"2"	"1"	"1198"	"131.8"	"6.71"	"255.33"	"2.08"	"1"	"1"	"cell adhesion;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi;other cell component"	""	"Pf00041"	"22862"	"ENSG00000102531"	"FNDC3A"	"B4DYG1; hsa:22862; Q5HYC9; Q5JVF8; Q5JVF9; Q6EVH3; Q6EVH4; Q6N020; Q6P9D5; Q6ZME4; Q9H1W1; Q9Y2H6"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q4V328"	"GRIP1-associated protein 1 OS=Homo sapiens OX=9606 GN=GRIPAP1 PE=1 SV=2"	"1"	"1"	"1"	"1"	"841"	"95.9"	"5.11"	""	"2.08"	""	"1"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	""	"56850"	"ENSG00000068400"	"GRIPAP1"	"A6NL78; hsa:56850; Q3MJ75; Q4V327; Q4V328; Q4V330; Q5HYG1; Q6N046; Q96DH8; Q9NQ43; Q9ULQ3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95721"	"Synaptosomal-associated protein 29 OS=Homo sapiens OX=9606 GN=SNAP29 PE=1 SV=1"	"4"	"1"	"2"	"1"	"258"	"29.0"	"5.81"	"250.57"	"2.08"	"1"	"1"	"cell-cell signaling;cell organization and biogenesis;other metabolic processes;transport"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	""	"9342"	"ENSG00000099940"	"SNAP29"	"hsa:9342; O95721"	"Ciliary landscape; 22q11.2 copy number variation syndrome"	"Neutrophil degranulation; Intra-Golgi traffic"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92766"	"Ras-responsive element-binding protein 1 OS=Homo sapiens OX=9606 GN=RREB1 PE=1 SV=3"	"1"	"1"	"1"	"1"	"1687"	"181.3"	"6.98"	""	"2.07"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00096, Pf13909, Pf13912"	"6239"	"ENSG00000124782"	"RREB1"	"A2RRF5; E2GM80; E2GM81; hsa:6239; O75567; O75568; Q5VYB2; Q6BEP5; Q6BEP6; Q6BEP8; Q86SU2; Q92766; Q9Y474"	""	""	"0"	"0"	"45.4"	"104.6"	"100.2"	"43.2"	"86.5"	"47.6"	"106.0"	"87.2"	"106.2"	"117.5"	"140.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NTX5"	"Ethylmalonyl-CoA decarboxylase OS=Homo sapiens OX=9606 GN=ECHDC1 PE=1 SV=2"	"4"	"1"	"1"	"1"	"307"	"33.7"	"8.21"	""	"2.07"	""	"1"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf00378"	"55862"	"ENSG00000093144"	"ECHDC1"	"A6NFJ5; B7Z8S0; E9PEN7; E9PR31; F8W851; hsa:55862; Q5TEF6; Q5TEF7; Q5TEG0; Q5TEG4; Q9NTX5; Q9NZ30; V9HW18"	"Fatty acid biosynthesis"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UPN6"	"SR-related and CTD-associated factor 8 OS=Homo sapiens OX=9606 GN=SCAF8 PE=1 SV=1"	"1"	"1"	"1"	"1"	"1271"	"140.4"	"8.29"	""	"2.07"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf04818"	"22828"	"ENSG00000213079"	"SCAF8"	"B7Z888; hsa:22828; Q5TBU6; Q6NSK3; Q9BQN8; Q9BX43; Q9UPN6"	""	""	"0"	"0"	"38.0"	"95.2"	"90.0"	"28.8"	"85.7"	"38.5"	"100.1"	"80.7"	"107.0"	"139.0"	"155.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NC60"	"Nitric oxide-associated protein 1 OS=Homo sapiens OX=9606 GN=NOA1 PE=1 SV=2"	"1"	"1"	"2"	"1"	"698"	"78.4"	"8.66"	"261.97"	"2.07"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf01926"	"84273"	"ENSG00000084092"	"NOA1"	"hsa:84273; Q8N7L6; Q8NC60; Q9BSQ9"	""	""	"0"	"0"	"7.3"	"15.8"	"9.1"	"2.5"	"9.0"	"9.1"	"9.6"	"7.9"	"11.1"	"11.6"	"19.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NCM8"	"Cytoplasmic dynein 2 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC2H1 PE=1 SV=4"	"0"	"1"	"1"	"1"	"4307"	"492.3"	"6.54"	""	"2.07"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03028, Pf08385, Pf08393, Pf12774, Pf12775, Pf12777, Pf12780, Pf12781, Pf18198, Pf18199"	"79659"	"ENSG00000187240"	"DYNC2H1"	"hsa:79659; O00432; Q16693; Q3C1U8; Q4AC93; Q6ZMX7; Q6ZUM6; Q7Z363; Q8N977; Q8NCM8; Q92815; Q9HAE4"	"Intraflagellar transport proteins binding to dynein; Genes related to primary cilium development (based on CRISPR); Ciliopathies; 3q29 copy number variation syndrome; Bardet-Biedl syndrome"	"Hedgehog 'off' state; Intraflagellar transport"	"7"	"0"	"6.1"	"14.4"	"12.9"	"5.5"	"9.3"	"4.6"	"12.1"	"17.3"	"14.3"	"20.0"	"33.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O76094"	"Signal recognition particle subunit SRP72 OS=Homo sapiens OX=9606 GN=SRP72 PE=1 SV=3"	"2"	"1"	"2"	"1"	"671"	"74.6"	"9.26"	"293.60"	"2.07"	"1"	"1"	"transport"	"cytosol;ER/Golgi;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf08492, Pf13181, Pf17004"	"6731"	"ENSG00000174780"	"SRP72"	"G5E9Z8; hsa:6731; O76094; Q7Z3C0"	""	"SRP-dependent cotranslational protein targeting to membrane"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96HC4"	"PDZ and LIM domain protein 5 OS=Homo sapiens OX=9606 GN=PDLIM5 PE=1 SV=5"	"2"	"1"	"1"	"1"	"596"	"63.9"	"8.21"	""	"2.06"	""	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412, Pf00595, Pf15936"	"10611"	"ENSG00000163110"	"PDLIM5"	"A8K6F9; D6RB78; E9PBF5; hsa:10611; O60705; Q56VN4; Q5UW38; Q8WVK0; Q96HC4"	"Extracellular vesicles in the crosstalk of cardiac cells"	"Neurexins and neuroligins"	"2"	"0"	"55.6"	"139.5"	"133.9"	"59.3"	"124.0"	"69.3"	"121.8"	"98.6"	"106.3"	"165.3"	"259.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P42575"	"Caspase-2 OS=Homo sapiens OX=9606 GN=CASP2 PE=1 SV=2"	"3"	"1"	"1"	"1"	"452"	"50.7"	"6.81"	""	"2.06"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00619, Pf00656"	"835"	"ENSG00000106144"	"CASP2"	"A8K5F9; D3DXD6; E9PDN0; hsa:835; P42575; P42576; Q59F21; Q7KZL6; Q86UJ3; Q9BUP7; Q9BZK9; Q9BZL0"	"Apoptosis modulation and signaling; Parkinson's disease pathway; Apoptosis; Apoptosis modulation by HSP70; Acute viral myocarditis"	"TP53 Regulates Transcription of Caspase Activators and Caspases; NOD1/2 Signaling Pathway; NADE modulates death signalling"	"8"	"0"	"99.8"	"260.9"	"500.2"	"81.8"	"606.2"	"175.9"	"139.6"	"54.8"	"113.0"	"111.8"	"144.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TBB5"	"Kelch domain-containing protein 4 OS=Homo sapiens OX=9606 GN=KLHDC4 PE=1 SV=1"	"2"	"1"	"2"	"1"	"520"	"57.9"	"5.72"	"259.03"	"2.06"	"1"	"1"	""	""	""	"Pf07646, Pf13418, Pf13854, Pf13964"	"54758"	"ENSG00000104731"	"KLHDC4"	"D3DUN3; D3DUN4; D3DUN5; hsa:54758; Q8TBB5; Q96F29; Q9BVN3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IWV7"	"E3 ubiquitin-protein ligase UBR1 OS=Homo sapiens OX=9606 GN=UBR1 PE=1 SV=1"	"1"	"1"	"2"	"1"	"1749"	"200.1"	"6.01"	"257.23"	"2.06"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf02207, Pf02617, Pf18995"	"197131"	"ENSG00000159459"	"UBR1"	"hsa:197131; O60708; O75492; Q14D45; Q68DN9; Q8IWV7; Q8IWY6; Q96JY4"	""	"Antigen processing: Ubiquitination & Proteasome degradation"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7L0J3"	"Synaptic vesicle glycoprotein 2A OS=Homo sapiens OX=9606 GN=SV2A PE=1 SV=1"	"2"	"1"	"1"	"1"	"742"	"82.6"	"5.57"	""	"2.06"	""	"1"	"cell-cell signaling;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"transporter activity;other molecular function"	"Pf00083, Pf07690"	"9900"	"ENSG00000159164"	"SV2A"	"D3DUZ7; hsa:9900; O94841; Q5QNX8; Q7L0J3; Q7Z3L6; Q8NBJ6; Q9BVZ9"	""	"Toxicity of botulinum toxin type A (botA); Toxicity of botulinum toxin type D (botD); Toxicity of botulinum toxin type F (botF); Toxicity of botulinum toxin type E (botE)"	"4"	"0"	"6.8"	"13.3"	"10.6"	"8.0"	"13.1"	"4.5"	"9.4"	"6.3"	"11.1"	"15.6"	"12.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13017"	"Rho GTPase-activating protein 5 OS=Homo sapiens OX=9606 GN=ARHGAP5 PE=1 SV=2"	"1"	"1"	"1"	"1"	"1502"	"172.4"	"6.62"	""	"2.06"	""	"1"	"cell adhesion;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00071, Pf00620, Pf01846, Pf16512, Pf19518"	"394"	"ENSG00000100852"	"ARHGAP5"	"A1L375; A1L376; A8KAA1; D3DS89; D3DS90; hsa:394; Q05BE8; Q05BU8; Q13017; Q59ER0; Q6DHZ3"	"Focal adhesion"	"RHOC GTPase cycle; RND2 GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RHOG GTPase cycle; RAC3 GTPase cycle; RHOB GTPase cycle; RHOD GTPase cycle; RHOJ GTPase cycle; RHOF GTPase cycle; RND3 GTPase cycle; RND1 GTPase cycle"	"15"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96FV9"	"THO complex subunit 1 OS=Homo sapiens OX=9606 GN=THOC1 PE=1 SV=1"	"2"	"1"	"1"	"1"	"657"	"75.6"	"4.98"	""	"2.06"	""	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;transport;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00531, Pf11957"	"9984"	"ENSG00000079134"	"THOC1"	"B2RBP6; hsa:9984; Q15219; Q64I72; Q64I73; Q96FV9"	""	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60284"	"Suppression of tumorigenicity 18 protein OS=Homo sapiens OX=9606 GN=ST18 PE=1 SV=1"	"1"	"1"	"1"	"1"	"1047"	"115.1"	"6.06"	""	"2.05"	""	"1"	"RNA metabolism OR transcription;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01530, Pf08474"	"9705"	"ENSG00000147488"	"ST18"	"hsa:9705; O60284; Q17RY1"	""	""	"0"	"0"	"27.8"	"85.6"	"75.4"	"30.4"	"63.8"	"37.5"	"99.5"	"125.0"	"252.6"	"424.7"	"587.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95104"	"SR-related and CTD-associated factor 4 OS=Homo sapiens OX=9606 GN=SCAF4 PE=1 SV=3"	"1"	"1"	"2"	"1"	"1147"	"125.8"	"9.55"	"242.67"	"2.05"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf04818"	"57466"	"ENSG00000156304"	"SCAF4"	"C9JLZ0; hsa:57466; O95104; Q0P5W8; Q6P1M5; Q8N3I8; Q9UFM1; Q9ULP8"	""	""	"0"	"0"	"15.7"	"94.8"	"64.7"	"7.9"	"65.2"	"22.8"	"42.9"	"27.9"	"53.6"	"57.4"	"99.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6IN85"	"Serine/threonine-protein phosphatase 4 regulatory subunit 3A OS=Homo sapiens OX=9606 GN=PPP4R3A PE=1 SV=1"	"1"	"1"	"2"	"1"	"833"	"95.3"	"4.94"	"256.03"	"2.05"	"1"	"1"	"protein metabolism;other metabolic processes;stress response"	"cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity"	"Pf04802"	"55671"	"ENSG00000100796"	"PPP4R3A"	"hsa:55671; Q69YK6; Q6IN85; Q86U23; Q86YI7; Q8IVG1; Q9H3F1; Q9H7U8; Q9NV01; Q9NWP1"	"16p11.2 proximal deletion syndrome"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P07311"	"Acylphosphatase-1 OS=Homo sapiens OX=9606 GN=ACYP1 PE=1 SV=2"	"17"	"2"	"2"	"2"	"99"	"11.3"	"9.31"	"264.63"	"2.04"	"1"	"1"	"other metabolic processes"	""	"other molecular function"	"Pf00708"	"97"	"ENSG00000119640"	"ACYP1"	"A6NDV8; B2R590; hsa:97; P07311"	""	""	"0"	"0"	"122.0"	"206.2"	"222.2"	"99.0"	"223.5"	"135.5"	"216.8"	"144.6"	"230.9"	"314.9"	"513.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P14550"	"Aldo-keto reductase family 1 member A1 OS=Homo sapiens OX=9606 GN=AKR1A1 PE=1 SV=3"	"6"	"2"	"2"	"1"	"325"	"36.6"	"6.79"	""	"2.04"	""	"2"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00248"	"10327"	"ENSG00000117448"	"AKR1A1"	"A8KAL8; D3DQ04; hsa:10327; P14550; Q6IAZ4"	"Benzo(a)pyrene metabolism; Metapathway biotransformation Phase I and II"	"Glutathione conjugation; Formation of xylulose-5-phosphate"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IVF4"	"Dynein heavy chain 10, axonemal OS=Homo sapiens OX=9606 GN=DNAH10 PE=1 SV=4"	"0"	"1"	"1"	"1"	"4471"	"514.5"	"5.88"	""	"2.04"	""	"1"	"other biological processes"	"cytoskeleton"	"cytoskeletal activity;other molecular function"	"Pf03028, Pf08385, Pf08393, Pf12774, Pf12775, Pf12777, Pf12780, Pf12781, Pf17852, Pf17857, Pf18198, Pf18199"	"196385"	"ENSG00000197653"	"DNAH10"	"C9JMF5; hsa:196385; O95495; Q6ZUC9; Q6ZUP6; Q8IVF4; Q8N761"	""	""	"0"	"0"	"75.1"	"147.9"	"153.4"	"61.4"	"138.1"	"61.4"	"168.9"	"117.4"	"185.7"	"181.5"	"307.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15294"	"UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Homo sapiens OX=9606 GN=OGT PE=1 SV=3"	"2"	"2"	"2"	"2"	"1046"	"116.9"	"6.70"	"255.06"	"2.04"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00515, Pf13181, Pf13414, Pf13424, Pf13844"	"8473"	"ENSG00000147162"	"OGT"	"hsa:8473; O15294; Q7Z3K0; Q8WWM8; Q96CC1; Q9UG57"	"Ectoderm differentiation; Ectoderm differentiation; Pleural mesothelioma"	"UCH proteinases; Formation of WDR5-containing histone-modifying complexes; Regulation of necroptotic cell death; HATs acetylate histones"	"8"	"0"	"54.7"	"94.5"	"94.8"	"31.7"	"82.5"	"64.3"	"46.9"	"42.8"	"63.5"	"72.7"	"86.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P21695"	"Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic OS=Homo sapiens OX=9606 GN=GPD1 PE=1 SV=4"	"4"	"1"	"1"	"1"	"349"	"37.5"	"6.18"	""	"2.03"	""	"1"	"other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf01210, Pf07479"	"2819"	"ENSG00000167588"	"GPD1"	"F8W1L5; hsa:2819; P21695; Q8N1B0"	"HIF1A and PPARG regulation of glycolysis; Triacylglyceride synthesis"	"Synthesis of PA"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H1I8"	"Activating signal cointegrator 1 complex subunit 2 OS=Homo sapiens OX=9606 GN=ASCC2 PE=1 SV=3"	"1"	"1"	"1"	"1"	"757"	"86.3"	"5.16"	""	"2.03"	""	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02845"	"84164"	"ENSG00000100325"	"ASCC2"	"B7Z8E0; F5H6J9; hsa:84164; Q4TT54; Q8TAZ0; Q9H1I8; Q9H711; Q9H9D6"	""	"ALKBH3 mediated reversal of alkylation damage"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P086"	"Mediator of RNA polymerase II transcription subunit 11 OS=Homo sapiens OX=9606 GN=MED11 PE=1 SV=2"	"16"	"1"	"2"	"1"	"117"	"13.1"	"5.96"	"273.67"	"2.03"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf10280"	"400569"	"ENSG00000161920"	"MED11"	"hsa:400569; Q6NS89; Q9P086"	""	"PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q5T447"	"E3 ubiquitin-protein ligase HECTD3 OS=Homo sapiens OX=9606 GN=HECTD3 PE=1 SV=1"	"2"	"1"	"2"	"1"	"861"	"97.1"	"5.64"	"245.68"	"2.03"	"1"	"1"	"protein metabolism;other metabolic processes"	"other cell component"	"other molecular function"	"Pf00632, Pf03256"	"79654"	"ENSG00000126107"	"HECTD3"	"B3KPV7; B3KRH4; hsa:79654; Q5T447; Q5T448; Q9H783"	""	"Antigen processing: Ubiquitination & Proteasome degradation"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"P21359"	"Neurofibromin OS=Homo sapiens OX=9606 GN=NF1 PE=1 SV=2"	"0"	"1"	"1"	"1"	"2839"	"319.2"	"7.39"	""	"2.03"	""	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00616, Pf13716"	"4763"	"ENSG00000196712"	"NF1"	"hsa:4763; O00662; P21359; Q14284; Q14930; Q14931; Q9UMK3"	"Pilocytic astrocytoma; Glioblastoma signaling pathways; Aryl hydrocarbon receptor pathway; MECP2 and associated Rett syndrome; MAPK signaling pathway; Ras signaling; Transcription co-factors SKI and SKIL protein partners; Synaptic signaling pathways associated with autism spectrum disorder; Fragile X syndrome; Melanoma; EGFR tyrosine kinase inhibitor resistance"	"Regulation of RAS by GAPs; RAS signaling downstream of NF1 loss-of-function variants"	"13"	"0"	"8.6"	"29.0"	"28.9"	"8.1"	"27.1"	"11.6"	"20.4"	"9.9"	"28.1"	"37.4"	"66.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NZC9"	"SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 OS=Homo sapiens OX=9606 GN=SMARCAL1 PE=1 SV=1"	"1"	"1"	"2"	"1"	"954"	"105.9"	"9.06"	"257.33"	"2.03"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf07443"	"50485"	"ENSG00000138375"	"SMARCAL1"	"A6NEH0; hsa:50485; Q53R00; Q96AY1; Q9NXQ5; Q9NZC9; Q9UFH3; Q9UI93"	"Primary focal segmental glomerulosclerosis (FSGS); Nephrotic syndrome"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5VWK0"	"Neuroblastoma breakpoint family member 6 OS=Homo sapiens OX=9606 GN=NBPF6 PE=2 SV=2"	"2"	"1"	"1"	"1"	"638"	"72.2"	"4.93"	""	"2.02"	""	"1"	""	"other cell component"	""	"Pf06758"	"653149"	"ENSG00000186086"	"NBPF6"	"A4QN25; hsa:653149; Q5VWK0"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BVJ6"	"U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1"	"1"	"1"	"1"	"1"	"771"	"87.9"	"7.87"	""	"2.02"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf04615"	"10813"	"ENSG00000156697"	"UTP14A"	"A8K7A3; A8MVQ1; B4DQ08; E9PEL7; hsa:10813; Q5JYF1; Q9BVJ6"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8IVL6"	"Prolyl 3-hydroxylase 3 OS=Homo sapiens OX=9606 GN=P3H3 PE=1 SV=1"	"3"	"1"	"1"	"1"	"736"	"81.8"	"6.32"	""	"2.02"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"ER/Golgi;other cell component"	"other molecular function"	"Pf13640"	"10536"	"ENSG00000110811"	"P3H3"	"hsa:10536; Q13512; Q15740; Q66K32; Q6NX61; Q7L2T1; Q8IVL6"	""	"Collagen biosynthesis and modifying enzymes"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H4M9"	"EH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=EHD1 PE=1 SV=2"	"2"	"1"	"2"	"1"	"534"	"60.6"	"6.83"	"286.60"	"2.02"	"1"	"1"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00350, Pf12763, Pf16880, Pf18150"	"10938"	"ENSG00000110047"	"EHD1"	"hsa:10938; O14611; Q2M3Q4; Q9H4M9; Q9UNR3"	"Insulin signaling"	"Factors involved in megakaryocyte development and platelet production"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P13489"	"Ribonuclease inhibitor OS=Homo sapiens OX=9606 GN=RNH1 PE=1 SV=2"	"3"	"1"	"1"	"1"	"461"	"49.9"	"4.82"	""	"2.00"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf13516, Pf18779"	"6050"	"ENSG00000023191; ENSG00000276230"	"RNH1"	"hsa:6050; P13489; Q8IZK8; Q96FD7; Q9BQ80; Q9UDK6"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O14802"	"DNA-directed RNA polymerase III subunit RPC1 OS=Homo sapiens OX=9606 GN=POLR3A PE=1 SV=2"	"1"	"1"	"2"	"1"	"1390"	"155.5"	"8.48"	"382.78"	"0.00"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00623, Pf04983, Pf04997, Pf04998, Pf05000"	"11128"	"ENSG00000148606"	"POLR3A"	"hsa:11128; O14802; Q8IW34; Q8TCW5"	"Pyrimidine metabolism; Cytosolic DNA-sensing pathway"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation"	"9"	"0"	"6.5"	"11.7"	"14.1"	"5.5"	"18.9"	"6.2"	"7.5"	"4.8"	"5.9"	"13.3"	"19.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51571"	"Translocon-associated protein subunit delta OS=Homo sapiens OX=9606 GN=SSR4 PE=1 SV=1"	"7"	"1"	"2"	"1"	"173"	"19.0"	"6.15"	"374.16"	"0.00"	"1"	"1"	""	"other membranes;ER/Golgi;other cell component"	""	"Pf05404"	"6748"	"ENSG00000180879"	"SSR4"	"A8K378; hsa:6748; P51571; Q53XY1"	"VEGFA-VEGFR2 signaling"	"SRP-dependent cotranslational protein targeting to membrane"	"2"	"0"	"16.5"	"48.3"	"42.9"	"9.3"	"41.7"	"21.5"	"25.4"	"19.2"	"27.7"	"31.4"	"48.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBP0"	"Spastin OS=Homo sapiens OX=9606 GN=SPAST PE=1 SV=1"	"2"	"1"	"2"	"1"	"616"	"67.2"	"9.64"	"313.61"	"0.00"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00004, Pf09336, Pf17862"	"6683"	"ENSG00000021574"	"SPAST"	"A7E2A7; hsa:6683; Q9UBP0; Q9UPR9"	""	"Sealing of the nuclear envelope (NE) by ESCRT-III"	"1"	"0"	"14.7"	"31.4"	"38.9"	"16.0"	"37.2"	"14.1"	"63.5"	"40.2"	"72.5"	"82.5"	"146.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BQ70"	"Transcription factor 25 OS=Homo sapiens OX=9606 GN=TCF25 PE=1 SV=1"	"3"	"1"	"2"	"1"	"676"	"76.6"	"6.35"	"307.29"	"0.00"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04910"	"22980"	"ENSG00000141002"	"TCF25"	"hsa:22980; Q2MK75; Q9BQ70; Q9UPV3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q9H3Q1"	"Cdc42 effector protein 4 OS=Homo sapiens OX=9606 GN=CDC42EP4 PE=1 SV=1"	"3"	"1"	"2"	"1"	"356"	"38.0"	"5.19"	"300.51"	"0.00"	"1"	"1"	"cell organization and biogenesis;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00786, Pf14957"	"23580"	"ENSG00000179604"	"CDC42EP4"	"B3KUS7; hsa:23580; O95828; Q96FT3; Q9H3Q1"	""	"CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RAC2 GTPase cycle"	"4"	"0"	"8.3"	"10.1"	"11.2"	"6.5"	"10.0"	"10.2"	"8.7"	"9.3"	"14.3"	"10.7"	"16.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H425"	"Uncharacterized protein C1orf198 OS=Homo sapiens OX=9606 GN=C1orf198 PE=1 SV=1"	"4"	"1"	"2"	"1"	"327"	"36.3"	"5.72"	"256.40"	"0.00"	"1"	"1"	""	"cytosol"	""	"Pf15797"	"84886"	"ENSG00000119280"	"C1orf198"	"A8K8R8; B3KTW1; G5EA08; hsa:84886; Q9H425"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z2Z2"	"Elongation factor-like GTPase 1 OS=Homo sapiens OX=9606 GN=EFL1 PE=1 SV=2"	"2"	"2"	"2"	"2"	"1120"	"125.4"	"5.91"	"235.70"	"0.00"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00009, Pf00679, Pf14492"	"79631"	"ENSG00000140598"	"EFL1"	"A6NKY5; B7Z6I0; hsa:79631; Q7Z2Z2; Q9H8Z6"	"Genetic causes of porto-sinusoidal vascular disease"	""	"1"	"0"	"7.5"	"30.7"	"21.9"	"3.1"	"27.2"	"10.7"	"13.7"	"15.0"	"17.5"	"23.7"	"36.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12800"	"Alpha-globin transcription factor CP2 OS=Homo sapiens OX=9606 GN=TFCP2 PE=1 SV=2"	"3"	"1"	"1"	"1"	"502"	"57.2"	"5.80"	""	"0.00"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04516, Pf18016"	"7024"	"ENSG00000135457"	"TFCP2"	"A8K5E9; hsa:7024; Q12800; Q12801; Q9UD75; Q9UD77"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NQX3"	"Gephyrin OS=Homo sapiens OX=9606 GN=GPHN PE=1 SV=1"	"1"	"1"	"1"	"1"	"736"	"79.7"	"5.43"	""	"0.00"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00994, Pf03453, Pf03454"	"10243"	"ENSG00000171723"	"GPHN"	"hsa:10243; Q96KU4; Q9H4E9; Q9NQX3; Q9P2G2"	"Splicing factor NOVA regulated synaptic proteins; GABA receptor signaling; Fragile X syndrome"	"Molybdenum cofactor biosynthesis"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99720"	"Sigma non-opioid intracellular receptor 1 OS=Homo sapiens OX=9606 GN=SIGMAR1 PE=1 SV=1"	"22"	"1"	"1"	"1"	"223"	"25.1"	"5.96"	""	"0.00"	""	"1"	"cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf04622"	"10280"	"ENSG00000147955"	"SIGMAR1"	"D3DRM7; hsa:10280; O00673; O00725; Q0Z9W6; Q153Z1; Q2TSD1; Q53GN2; Q7Z653; Q8N7H3; Q99720; Q9NYX0"	""	"Potential therapeutics for SARS"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14694"	"Ubiquitin carboxyl-terminal hydrolase 10 OS=Homo sapiens OX=9606 GN=USP10 PE=1 SV=2"	"1"	"1"	"1"	"1"	"798"	"87.1"	"5.31"	""	"0.00"	""	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00443, Pf07145"	"9100"	"ENSG00000103194"	"USP10"	"B2RDJ8; B4DS84; hsa:9100; Q14694; Q9BWG7; Q9NSL7"	"VEGFA-VEGFR2 signaling"	"Ub-specific processing proteases; Termination of translesion DNA synthesis"	"3"	"0"	"12.4"	"23.3"	"27.7"	"5.2"	"27.6"	"7.8"	"15.3"	"8.9"	"13.2"	"26.9"	"36.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5H7"	"Protocadherin alpha-5 OS=Homo sapiens OX=9606 GN=PCDHA5 PE=2 SV=1"	"2"	"1"	"1"	"1"	"936"	"102.0"	"5.43"	""	"0.00"	""	"1"	"cell adhesion;developmental processes"	"plasma membrane;other membranes"	"other molecular function"	"Pf00028, Pf08266, Pf15974"	"56143"	"ENSG00000204965"	"PCDHA5"	"hsa:56143; O75284; Q8N4R3; Q9Y5H7"	""	""	"0"	"0"	"112.5"	"248.1"	"267.0"	"112.8"	"257.2"	"137.2"	"156.5"	"115.6"	"171.6"	"230.3"	"242.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P00451"	"Coagulation factor VIII OS=Homo sapiens OX=9606 GN=F8 PE=1 SV=1"	"0"	"1"	"1"	"1"	"2351"	"266.8"	"7.36"	""	"0.00"	""	"1"	"protein metabolism;other metabolic processes;stress response"	"non-structural extracellular;plasma membrane;other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf00394, Pf00754, Pf07731, Pf07732"	"2157"	"ENSG00000185010"	"F8"	"hsa:2157; P00451; Q14286; Q5HY69"	"Blood clotting cascade; Complement and coagulation cascades"	"Platelet degranulation ; COPII-mediated vesicle transport; Cargo concentration in the ER; Gamma carboxylation, hypusine formation and arylsulfatase activation; Defective F8 sulfation at Y1699; Intrinsic Pathway of Fibrin Clot Formation; Common Pathway of Fibrin Clot Formation; Defective factor IX causes thrombophilia; Defective F8 accelerates dissociation of the A2 domain; Defective F8 cleavage by thrombin; Defective F8 binding to von Willebrand factor; Defective F8 binding to the cell membrane; Defective cofactor function of FVIIIa variant; Defective F8 secretion; Defective F9 variant does not activate FX"	"17"	"0"	"42.7"	"47.4"	"64.1"	"46.3"	"75.2"	"47.8"	"127.4"	"118.5"	"189.7"	"289.0"	"515.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86WG5"	"Myotubularin-related protein 13 OS=Homo sapiens OX=9606 GN=SBF2 PE=1 SV=1"	"1"	"1"	"1"	"1"	"1849"	"208.3"	"7.06"	""	"0.00"	""	"1"	"other metabolic processes;developmental processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf02141, Pf02893, Pf03456, Pf06602, Pf12335"	"81846"	"ENSG00000133812"	"SBF2"	"hsa:81846; Q3MJF0; Q68DQ3; Q6P459; Q6PJD1; Q7Z325; Q7Z621; Q86VE2; Q86WG5; Q96FE2; Q9C097"	"Intracellular trafficking proteins involved in CMT neuropathy"	"Synthesis of PIPs at the plasma membrane; RAB GEFs exchange GTP for GDP on RABs"	"3"	"0"	"3.2"	"5.9"	"9.2"	"5.1"	"8.3"	"3.9"	"7.5"	"11.4"	"17.7"	"25.9"	"44.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z3B3"	"KAT8 regulatory NSL complex subunit 1 OS=Homo sapiens OX=9606 GN=KANSL1 PE=1 SV=2"	"1"	"1"	"1"	"1"	"1105"	"121.0"	"8.81"	""	"0.00"	""	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"148.7"	"206.0"	"220.9"	"113.9"	"263.8"	"148.6"	"400.2"	"278.3"	"402.7"	"466.2"	"621.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NCU4"	"Coiled-coil domain-containing protein 191 OS=Homo sapiens OX=9606 GN=CCDC191 PE=2 SV=1"	"1"	"1"	"1"	"1"	"936"	"110.5"	"9.60"	""	"0.00"	""	"1"	""	""	"other molecular function"	""	"57577"	"ENSG00000163617"	"CCDC191"	"B4DYL1; hsa:57577; Q8NCU4; Q9P2E0"	""	""	"0"	"0"	"62.6"	"411.8"	"347.6"	"49.5"	"308.4"	"84.2"	"97.9"	"69.3"	"98.6"	"128.8"	"252.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P22105"	"Tenascin-X OS=Homo sapiens OX=9606 GN=TNXB PE=1 SV=5"	"1"	"1"	"1"	"1"	"4244"	"458.1"	"5.17"	""	"0.00"	""	"1"	"cell adhesion;cell organization and biogenesis;other metabolic processes;developmental processes;other biological processes"	"extracellular matrix"	"signal transduction activity or receptor binding;extracellular structural activity;other molecular function"	"Pf00041, Pf00147, Pf07974, Pf18720"	"7148"	"ENSG00000168477; ENSG00000229353; ENSG00000236236"	"TNXB"	"hsa:7148; P22105; P78530; P78531; Q08424; Q08AM0; Q08AM1; Q59GU7; Q5SQD3; Q5ST74; Q7L8Q4; Q8N4R1; Q9NPK9; Q9UC10; Q9UC11; Q9UC12; Q9UC13; Q9UMG7"	"miRNA targets in ECM and membrane receptors; Focal adhesion; VEGFA-VEGFR2 signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway"	"ECM proteoglycans"	"6"	"0"	"0.0"	"11.0"	"18.5"	"6.5"	"10.2"	"0.0"	"12.7"	"7.2"	"13.8"	"16.1"	"16.8"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O95425"	"Supervillin OS=Homo sapiens OX=9606 GN=SVIL PE=1 SV=2"	"1"	"1"	"1"	"1"	"2214"	"247.6"	"6.98"	""	"0.00"	""	"1"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00626, Pf02209"	"6840"	"ENSG00000197321"	"SVIL"	"D3DRW9; hsa:6840; M1J557; O60611; O60612; O95425; Q5VZK5; Q5VZK6; Q9H1R7"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7LBC6"	"Lysine-specific demethylase 3B OS=Homo sapiens OX=9606 GN=KDM3B PE=1 SV=2"	"1"	"1"	"1"	"1"	"1761"	"191.5"	"7.18"	""	"0.00"	""	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02373"	"51780"	"ENSG00000120733"	"KDM3B"	"A6H8X7; hsa:51780; Q7LBC6; Q9BVH6; Q9BW93; Q9BZ52; Q9NYF4; Q9UPS0"	"Thermogenesis"	"HDMs demethylate histones"	"2"	"0"	"141.2"	"136.5"	"111.2"	"70.8"	"141.1"	"112.1"	"21.4"	"11.1"	"22.8"	"21.4"	"22.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51956"	"Serine/threonine-protein kinase Nek3 OS=Homo sapiens OX=9606 GN=NEK3 PE=1 SV=2"	"2"	"1"	"1"	"1"	"506"	"57.7"	"7.17"	""	"0.00"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"4752"	"ENSG00000136098"	"NEK3"	"A8K2J4; hsa:4752; P51956; Q5TAP2; Q8J023; Q8WUN5"	"Prolactin signaling pathway"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99962"	"Endophilin-A1 OS=Homo sapiens OX=9606 GN=SH3GL2 PE=1 SV=1"	"4"	"1"	"1"	"1"	"352"	"39.9"	"5.45"	""	"0.00"	""	"1"	"cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf03114, Pf07653"	"6456"	"ENSG00000107295"	"SH3GL2"	"B2R618; hsa:6456; Q99962; Q9NQK5"	"EGF/EGFR signaling pathway"	"Recycling pathway of L1; MHC class II antigen presentation; Lysosome Vesicle Biogenesis; Golgi Associated Vesicle Biogenesis; Cargo recognition for clathrin-mediated endocytosis; EGFR downregulation; Negative regulation of MET activity; InlB-mediated entry of Listeria monocytogenes into host cell; Retrograde neurotrophin signalling"	"11"	"0"	"17.1"	"30.8"	"20.4"	"9.3"	"11.8"	"9.1"	"31.4"	"49.0"	"41.8"	"69.5"	"90.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75880"	"Protein SCO1 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=SCO1 PE=1 SV=1"	"6"	"1"	"2"	"1"	"301"	"33.8"	"8.88"	""	"0.00"	""	"1"	"cell organization and biogenesis;other biological processes"	"other membranes;cytoskeleton;mitochondrion"	"other molecular function"	"Pf02630"	"6341"	"ENSG00000133028"	"SCO1"	"B2RDM0; hsa:6341; O75880"	"Electron transport chain: OXPHOS system in mitochondria; Copper homeostasis"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"5"	"0"	"180.2"	"358.8"	"427.0"	"205.6"	"479.4"	"250.8"	"520.1"	"241.0"	"389.2"	"428.1"	"379.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96HY6"	"DDRGK domain-containing protein 1 OS=Homo sapiens OX=9606 GN=DDRGK1 PE=1 SV=2"	"6"	"1"	"1"	"1"	"314"	"35.6"	"5.12"	""	"0.00"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"other membranes;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf09756"	"65992"	"ENSG00000198171"	"DDRGK1"	"A6NIU5; C9JSZ5; hsa:65992; Q96HY6; Q9BW47"	""	"RHOA GTPase cycle"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"A6NNM8"	"Tubulin polyglutamylase TTLL13P OS=Homo sapiens OX=9606 GN=TTLL13P PE=1 SV=2"	"1"	"1"	"1"	"1"	"815"	"93.6"	"8.91"	""	"0.00"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03133"	""	"ENSG00000213471"	"TTLL13"	"A6NNM8"	""	"Carboxyterminal post-translational modifications of tubulin"	"1"	"0"	"63.8"	"204.1"	"202.1"	"64.6"	"183.6"	"113.7"	"148.1"	"118.8"	"188.6"	"207.7"	"284.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96RU2"	"Ubiquitin carboxyl-terminal hydrolase 28 OS=Homo sapiens OX=9606 GN=USP28 PE=1 SV=1"	"1"	"1"	"1"	"1"	"1077"	"122.4"	"5.20"	""	"0.00"	""	"1"	"cell cycle OR cell proliferation;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00443"	"57646"	"ENSG00000048028"	"USP28"	"B0YJC0; B0YJC1; hsa:57646; Q6NZX9; Q96RU2; Q9P213"	""	"Ub-specific processing proteases"	"1"	"0"	"200.1"	"274.3"	"104.6"	"119.1"	"76.5"	"61.6"	"346.1"	"1094.9"	"591.3"	"741.9"	"1513.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H0W5"	"Coiled-coil domain-containing protein 8 OS=Homo sapiens OX=9606 GN=CCDC8 PE=1 SV=2"	"4"	"1"	"1"	"1"	"538"	"59.3"	"8.63"	""	"0.00"	""	"1"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	""	"Pf14893"	"83987"	"ENSG00000169515"	"CCDC8"	"hsa:83987; Q8TB26; Q9H0W5"	""	"Neddylation"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q86UW6"	"NEDD4-binding protein 2 OS=Homo sapiens OX=9606 GN=N4BP2 PE=1 SV=2"	"2"	"1"	"1"	"1"	"1770"	"198.7"	"5.21"	""	"0.00"	""	"1"	"DNA metabolism"	"cytosol"	"kinase activity;other molecular function"	"Pf01713, Pf08590, Pf13671"	"55728"	"ENSG00000078177"	"N4BP2"	"A0AVR3; hsa:55728; Q86UW6; Q9NVK2; Q9P2D4"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5VZE5"	"N-alpha-acetyltransferase 35, NatC auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA35 PE=1 SV=1"	"2"	"1"	"1"	"1"	"725"	"83.6"	"7.05"	""	"0.00"	""	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	""	"Pf04112"	"60560"	"ENSG00000135040"	"NAA35"	"hsa:60560; Q5VZE5; Q5VZE6; Q9H631; Q9H703"	""	"Retrograde transport at the Trans-Golgi-Network"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9GZR7"	"ATP-dependent RNA helicase DDX24 OS=Homo sapiens OX=9606 GN=DDX24 PE=1 SV=1"	"2"	"1"	"1"	"1"	"859"	"96.3"	"9.06"	""	"0.00"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00270, Pf00271"	"57062"	"ENSG00000089737; ENSG00000273761"	"DDX24"	"E7EMJ4; hsa:57062; Q4V9L5; Q9GZR7"	""	""	"0"	"0"	"17.7"	"27.7"	"34.1"	"20.3"	"33.1"	"24.9"	"24.7"	"21.2"	"36.6"	"36.5"	"41.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q3V6T2"	"Girdin OS=Homo sapiens OX=9606 GN=CCDC88A PE=1 SV=2"	"1"	"1"	"1"	"1"	"1871"	"215.9"	"6.21"	""	"0.00"	""	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf19047"	"55704"	"ENSG00000115355"	"CCDC88A"	"A1IGE7; B7ZM78; C9JG83; hsa:55704; Q3V6T2; Q53SF1; Q581G3; Q5HYD0; Q7Z339; Q7Z3C5"	"Mesodermal commitment pathway"	"RND3 GTPase cycle; RND1 GTPase cycle"	"3"	"0"	"29.5"	"54.4"	"59.4"	"24.8"	"54.6"	"37.4"	"104.0"	"79.2"	"97.6"	"107.0"	"132.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99102"	"Mucin-4 OS=Homo sapiens OX=9606 GN=MUC4 PE=1 SV=4"	"2"	"1"	"1"	"1"	"2169"	"231.4"	"6.27"	""	"0.00"	""	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"8.2"	"18.0"	"11.7"	"8.2"	"11.4"	"6.7"	"31.3"	"26.2"	"30.8"	"33.7"	"45.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P0DKV0"	"Putative spermatogenesis-associated protein 31C1 OS=Homo sapiens OX=9606 GN=SPATA31C1 PE=5 SV=1"	"2"	"1"	"1"	"1"	"1188"	"130.4"	"9.42"	""	"0.00"	""	"1"	"other biological processes"	"other membranes"	""	"Pf14650, Pf15371"	"441452"	""	"SPATA31C1"	"hsa:441452; P0DKV0"	""	""	"0"	"0"	"16.1"	"36.4"	"71.4"	"27.0"	"71.8"	"43.8"	"82.2"	"36.8"	"67.4"	"55.7"	"39.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BUK6"	"Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1"	"2"	"1"	"1"	"1"	"570"	"61.8"	"6.11"	""	"0.00"	""	"1"	"cell organization and biogenesis"	"other membranes;cytosol;mitochondrion;other cell component"	""	"Pf10644, Pf14881"	"55154"	"ENSG00000125459"	"MSTO1"	"hsa:55154; Q53GR8; Q5CZ69; Q5T717; Q68CT6; Q7LBZ8; Q7Z3M7; Q7Z558; Q8TE05; Q9BUK6; Q9NQX2; Q9NVU4"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P08572"	"Collagen alpha-2(IV) chain OS=Homo sapiens OX=9606 GN=COL4A2 PE=1 SV=4"	"2"	"1"	"1"	"1"	"1712"	"167.4"	"8.66"	""	"0.00"	""	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;extracellular matrix;ER/Golgi"	"extracellular structural activity"	"Pf01391, Pf01413"	"1284"	"ENSG00000134871"	"COL4A2"	"hsa:1284; P08572; Q14052; Q548C3; Q5VZA9; Q66K23"	"miRNA targets in ECM and membrane receptors; Focal adhesion; Hepatitis C and hepatocellular carcinoma; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Epithelial to mesenchymal transition in colorectal cancer; Small cell lung cancer; Pleural mesothelioma"	"Collagen degradation; Signaling by PDGF; Integrin cell surface interactions; ECM proteoglycans; NCAM1 interactions; Collagen chain trimerization; Non-integrin membrane-ECM interactions; Laminin interactions; Anchoring fibril formation; Crosslinking of collagen fibrils; Scavenging by Class A Receptors"	"22"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q06265"	"Exosome complex component RRP45 OS=Homo sapiens OX=9606 GN=EXOSC9 PE=1 SV=3"	"2"	"1"	"1"	"1"	"439"	"48.9"	"5.29"	""	"0.00"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01138, Pf03725"	"5393"	"ENSG00000123737"	"EXOSC9"	"hsa:5393; Q06265; Q12883; Q4W5P5; Q86Y41; Q86Y48"	"Ciliary landscape"	"Major pathway of rRNA processing in the nucleolus and cytosol; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	"7"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P18054"	"Polyunsaturated fatty acid lipoxygenase ALOX12 OS=Homo sapiens OX=9606 GN=ALOX12 PE=1 SV=4"	"3"	"1"	"1"	"1"	"663"	"75.6"	"6.21"	""	"0.00"	""	"1"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00305, Pf01477"	"239"	"ENSG00000108839"	"ALOX12"	"hsa:239; O95569; P18054; Q6ISF8; Q9UQM4"	"Eicosanoid metabolism via lipooxygenases (LOX); Prostaglandin and leukotriene metabolism in senescence ; Prostaglandin and leukotriene metabolism in senescence"	"Synthesis of 12-eicosatetraenoic acid derivatives; Synthesis of Lipoxins (LX); Biosynthesis of DPAn-3-derived maresins; Biosynthesis of DHA-derived SPMs; Biosynthesis of DPAn-6 SPMs; Synthesis of Hepoxilins (HX) and Trioxilins (TrX)"	"9"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13564"	"NEDD8-activating enzyme E1 regulatory subunit OS=Homo sapiens OX=9606 GN=NAE1 PE=1 SV=1"	"2"	"1"	"1"	"1"	"534"	"60.2"	"5.40"	""	"0.00"	""	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00899"	"8883"	"ENSG00000159593"	"NAE1"	"A6NCK0; A6NFN4; A8MU28; B2R700; B3KUP9; hsa:8883; Q13564"	"Alzheimer's disease and miRNA effects; Hijack of ubiquitination by SARS-CoV-2; Alzheimer's disease"	"Neddylation"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96K19"	"E3 ubiquitin-protein ligase RNF170 OS=Homo sapiens OX=9606 GN=RNF170 PE=1 SV=2"	"7"	"1"	"1"	"1"	"258"	"29.8"	"5.58"	""	"0.00"	""	"1"	"protein metabolism;other metabolic processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf00097, Pf06803"	"81790"	"ENSG00000120925"	"RNF170"	"D3DSY6; E9PIL4; hsa:81790; Q7Z483; Q86YC0; Q8IXR7; Q8N2B5; Q8N5G9; Q8NG30; Q96K19; Q9H0V6"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"IsMasterProtein"	"Q96RY7"	"Intraflagellar transport protein 140 homolog OS=Homo sapiens OX=9606 GN=IFT140 PE=1 SV=1"	"1"	"1"	"1"	"1"	"1462"	"165.1"	"6.04"	""	"0.00"	""	"1"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"cytoskeleton;other cell component"	""	""	"9742"	"ENSG00000187535"	"IFT140"	"A2A2A8; D3DU75; hsa:9742; O60332; Q96RY7; Q9UG52"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein; Genes related to primary cilium development (based on CRISPR); Ciliopathies; Bardet-Biedl syndrome"	"Intraflagellar transport; Hedgehog 'off' state"	"7"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"n/a"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99963"	"Endophilin-A3 OS=Homo sapiens OX=9606 GN=SH3GL3 PE=1 SV=1"	"4"	"1"	"1"	"1"	"347"	"39.3"	"5.38"	""	"0.00"	""	"1"	"cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"other membranes;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00018, Pf03114"	"6457"	"ENSG00000140600"	"SH3GL3"	"hsa:6457; O43553; O43554; Q99963"	"EGF/EGFR signaling pathway; Fragile X syndrome"	"Cargo recognition for clathrin-mediated endocytosis; NGF-stimulated transcription; EGFR downregulation; Negative regulation of MET activity; InlB-mediated entry of Listeria monocytogenes into host cell"	"8"	"0"	"107.2"	"179.6"	"198.6"	"85.5"	"183.5"	"103.3"	"175.7"	"107.7"	"175.2"	"183.4"	"281.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HCD6"	"Protein TANC2 OS=Homo sapiens OX=9606 GN=TANC2 PE=1 SV=3"	"1"	"1"	"1"	"1"	"1990"	"219.5"	"8.07"	""	"0.00"	""	"1"	"transport;other biological processes"	"other cell component"	""	"Pf12796, Pf13181"	"26115"	"ENSG00000170921"	"TANC2"	"hsa:26115; Q9HAC3; Q9HCD6; Q9NW88; Q9NXY9; Q9ULS2"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P33527"	"Multidrug resistance-associated protein 1 OS=Homo sapiens OX=9606 GN=ABCC1 PE=1 SV=3"	"1"	"1"	"1"	"1"	"1531"	"171.5"	"7.11"	""	"0.00"	""	"1"	"cell organization and biogenesis;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes"	"transporter activity;other molecular function"	"Pf00005, Pf00664"	"4363"	"ENSG00000103222; ENSG00000278183"	"ABCC1"	"A3RJX2; C9JPJ4; hsa:4363; O14819; O43333; P33527; P78419; Q59GI9; Q9UQ97; Q9UQ99; Q9UQA0"	"Irinotecan pathway; Leukotriene metabolic pathway; TROP2 regulatory signaling"	"ABC-family proteins mediated transport; Paracetamol ADME; Cytoprotection by HMOX1; Transport of RCbl within the body; Heme degradation; Synthesis of Leukotrienes (LT) and Eoxins (EX)"	"9"	"0"	"11.3"	"29.1"	"29.7"	"15.0"	"26.7"	"11.9"	"29.4"	"31.0"	"60.0"	"108.4"	"188.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P26572"	"Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase OS=Homo sapiens OX=9606 GN=MGAT1 PE=1 SV=2"	"2"	"1"	"1"	"1"	"445"	"50.8"	"9.16"	""	"0.00"	""	"1"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf03071"	"4245"	"ENSG00000131446"	"MGAT1"	"A8K404; B3KRU8; D3DWR1; hsa:4245; P26572; Q6IBE3"	"N-glycan biosynthesis; Cholesterol metabolism; Enterocyte cholesterol metabolism"	"Maturation of spike protein; Maturation of spike protein; N-glycan trimming and elongation in the cis-Golgi"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H814"	"Phosphorylated adapter RNA export protein OS=Homo sapiens OX=9606 GN=PHAX PE=1 SV=1"	"3"	"1"	"1"	"1"	"394"	"44.4"	"5.40"	""	"0.00"	""	"1"	"transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf10258"	"51808"	"ENSG00000164902"	"PHAX"	"hsa:51808; Q9H814; Q9H8W1"	""	"RNA polymerase II transcribes snRNA genes; snRNP Assembly"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q00013"	"55 kDa erythrocyte membrane protein OS=Homo sapiens OX=9606 GN=MPP1 PE=1 SV=2"	"3"	"1"	"1"	"1"	"466"	"52.3"	"7.37"	""	"0.00"	""	"1"	"other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;kinase activity"	"Pf00018, Pf00595, Pf00625"	"4354"	"ENSG00000130830"	"MPP1"	"B4DZV5; G3XAI1; hsa:4354; Q00013; Q2TSB6; Q5J7V5"	"MECP2 and associated Rett syndrome"	"Sensory processing of sound by outer hair cells of the cochlea"	"2"	"0"	"14.5"	"41.9"	"35.7"	"17.1"	"38.8"	"23.8"	"31.3"	"27.1"	"35.6"	"46.0"	"58.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q0VG06"	"Fanconi anemia core complex-associated protein 100 OS=Homo sapiens OX=9606 GN=FAAP100 PE=1 SV=3"	"2"	"1"	"1"	"1"	"881"	"93.4"	"5.29"	""	"0.00"	""	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf15146"	"80233"	"ENSG00000185504"	"FAAP100"	"A6NNM1; hsa:80233; Q0VG06; Q8N3F7; Q9BV13; Q9H6K7; Q9H7E8"	"DNA repair pathways, full network"	"Fanconi Anemia Pathway"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P78316"	"Nucleolar protein 14 OS=Homo sapiens OX=9606 GN=NOP14 PE=1 SV=3"	"1"	"1"	"1"	"1"	"857"	"97.6"	"7.58"	""	"0.00"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04147"	"8602"	"ENSG00000087269"	"NOP14"	"D3DVR6; hsa:8602; P78316; Q7LGI5; Q7Z6K0; Q8TBR6"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"12.3"	"11.3"	"14.8"	"9.2"	"20.4"	"23.0"	"27.1"	"10.6"	"20.6"	"18.1"	"17.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96Q06"	"Perilipin-4 OS=Homo sapiens OX=9606 GN=PLIN4 PE=1 SV=2"	"1"	"1"	"1"	"1"	"1357"	"134.3"	"8.73"	""	"0.00"	""	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"28.5"	"43.4"	"57.8"	"34.7"	"62.9"	"43.8"	"51.3"	"28.5"	"42.0"	"59.6"	"60.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NYF8"	"Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2"	"1"	"1"	"1"	"1"	"920"	"106.1"	"9.98"	""	"0.00"	""	"1"	"RNA metabolism OR transcription;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf15440"	"9774"	"ENSG00000029363"	"BCLAF1"	"A2RU75; B7ZM58; E1P586; hsa:9774; Q14673; Q86WU6; Q86WY0; Q9NYF8"	"Interactome of polycomb repressive complex 2 (PRC2)"	""	"1"	"0"	"27.2"	"119.5"	"107.2"	"13.4"	"94.2"	"25.7"	"86.9"	"46.9"	"101.3"	"140.6"	"315.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96M96"	"FYVE, RhoGEF and PH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=FGD4 PE=1 SV=2"	"1"	"1"	"1"	"1"	"766"	"86.6"	"6.13"	""	"0.00"	""	"1"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00169, Pf00621, Pf01363"	"121512"	"ENSG00000139132"	"FGD4"	"hsa:121512; Q6ULS2; Q8TCP6; Q96M96"	"Glucocorticoid receptor pathway; Nuclear receptors meta-pathway; Intracellular trafficking proteins involved in CMT neuropathy"	"CDC42 GTPase cycle; NRAGE signals death through JNK; G alpha (12/13) signalling events"	"6"	"0"	"20.4"	"78.2"	"71.0"	"15.7"	"54.2"	"23.9"	"24.9"	"22.6"	"30.3"	"38.9"	"71.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P02768"	"Serum albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2"	"3"	"2"	"4"	"2"	"609"	"69.3"	"6.28"	"851.90"	""	"2"	""	"stress response;other biological processes"	"non-structural extracellular;ER/Golgi;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00273"	"213"	"ENSG00000163631"	"ALB"	"E7ESS9; hsa:213; O95574; P02768; P04277; Q13140; Q645G4; Q68DN5; Q6UXK4; Q86YG0; Q8IUK7; Q9P157; Q9P1I7; Q9UHS3; Q9UJZ0"	"Selenium micronutrient network; Vitamin B12 metabolism; Folate metabolism; Complement system; VEGFA-VEGFR2 signaling"	"Cytoprotection by HMOX1; Scavenging of heme from plasma; Platelet degranulation ; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Aspirin ADME; Ciprofloxacin ADME; Recycling of bile acids and salts; Prednisone ADME; Heme degradation; HDL remodeling; Heme biosynthesis"	"17"	"0"	"26.9"	"115.5"	"142.6"	"21.7"	"72.0"	"32.5"	"55.0"	"51.0"	"370.6"	"84.6"	"163.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q12789"	"General transcription factor 3C polypeptide 1 OS=Homo sapiens OX=9606 GN=GTF3C1 PE=1 SV=4"	"1"	"2"	"2"	"2"	"2109"	"238.7"	"7.30"	"745.80"	""	"2"	""	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04182"	"2975"	"ENSG00000077235"	"GTF3C1"	"B2RP21; hsa:2975; Q12789; Q12838; Q6DKN9; Q9Y4W9"	""	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UQ84"	"Exonuclease 1 OS=Homo sapiens OX=9606 GN=EXO1 PE=1 SV=2"	"3"	"2"	"2"	"2"	"846"	"94.0"	"8.31"	"672.90"	""	"2"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00752, Pf00867"	"9156"	"ENSG00000174371"	"EXO1"	"hsa:9156; O60545; O75214; O75466; Q5T396; Q96IJ1; Q9UG38; Q9UNW0; Q9UQ84"	"DNA repair pathways, full network; DNA mismatch repair; Primary ovarian insufficiency"	"Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; Resolution of D-loop Structures through Holliday Junction Intermediates; Presynaptic phase of homologous DNA pairing and strand exchange; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"19"	"0"	"7.2"	"15.7"	"11.5"	"4.9"	"11.8"	"4.8"	"17.4"	"11.3"	"21.3"	"23.4"	"24.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99627"	"COP9 signalosome complex subunit 8 OS=Homo sapiens OX=9606 GN=COPS8 PE=1 SV=1"	"6"	"1"	"1"	"1"	"209"	"23.2"	"5.38"	"626.56"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf10075"	"10920"	"ENSG00000198612"	"COPS8"	"A8K1H6; hsa:10920; Q53QS9; Q99627"	"Ciliary landscape; 2q37 copy number variation syndrome"	"DNA Damage Recognition in GG-NER; Cargo recognition for clathrin-mediated endocytosis; Neddylation; Formation of TC-NER Pre-Incision Complex"	"6"	"0"	"31.6"	"110.3"	"106.7"	"41.1"	"99.8"	"36.7"	"89.5"	"57.8"	"100.4"	"102.1"	"176.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13185"	"Chromobox protein homolog 3 OS=Homo sapiens OX=9606 GN=CBX3 PE=1 SV=4"	"8"	"1"	"1"	"1"	"183"	"20.8"	"5.33"	"613.34"	""	"1"	""	"cell organization and biogenesis;stress response;other biological processes"	"other membranes;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00385, Pf01393"	"11335"	"ENSG00000122565"	"CBX3"	"hsa:11335; Q13185; Q96CD7; Q99409; Q9BVS3; Q9P0Z6"	"Exercise-induced circadian regulation; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; NIPBL role in DNA damage - Cornelia de Lange syndrome"	"RNA Polymerase I Promoter Escape; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Transcriptional Regulation by E2F6"	"6"	"0"	"28.6"	"109.5"	"95.3"	"29.4"	"99.9"	"32.6"	"78.7"	"56.4"	"74.5"	"87.7"	"138.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y2J2"	"Band 4.1-like protein 3 OS=Homo sapiens OX=9606 GN=EPB41L3 PE=1 SV=2"	"2"	"2"	"2"	"1"	"1087"	"120.6"	"5.19"	"601.44"	""	"2"	""	"cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf04382, Pf05902, Pf08736, Pf09379, Pf09380"	"23136"	"ENSG00000082397"	"EPB41L3"	"B7Z4I5; F5GX05; hsa:23136; O95713; Q9BRP5; Q9Y2J2"	"Splicing factor NOVA regulated synaptic proteins"	"Neurexins and neuroligins; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea"	"4"	"0"	"16.2"	"35.5"	"48.0"	"16.7"	"39.3"	"18.4"	"36.7"	"19.7"	"105.1"	"167.6"	"181.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60934"	"Nibrin OS=Homo sapiens OX=9606 GN=NBN PE=1 SV=1"	"2"	"1"	"1"	"1"	"754"	"84.9"	"6.90"	"584.21"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00498, Pf08599, Pf16508"	"4683"	"ENSG00000104320"	"NBN"	"B2R626; B2RNC5; hsa:4683; O60672; O60934; Q32NF7; Q53FM6; Q63HR6; Q7LDM2"	"miRNA regulation of DNA damage response; Homologous recombination; DDX1 as a regulatory component of the Drosha microprocessor; ATM signaling in development and disease ; Breast cancer pathway; DNA repair pathways, full network; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; Primary ovarian insufficiency; DNA damage response"	"Resolution of D-loop Structures through Holliday Junction Intermediates; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; Meiotic recombination; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; DNA Damage/Telomere Stress Induced Senescence; Nonhomologous End-Joining (NHEJ); HDR through MMEJ (alt-NHEJ); Sensing of DNA Double Strand Breaks"	"29"	"0"	"3.1"	"8.2"	"9.0"	"4.3"	"9.7"	"2.0"	"10.4"	"7.6"	"12.0"	"38.0"	"100.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92686"	"Neurogranin OS=Homo sapiens OX=9606 GN=NRGN PE=1 SV=1"	"19"	"1"	"1"	"1"	"78"	"7.6"	"7.87"	"572.71"	""	"1"	""	"developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00612"	"4900"	"ENSG00000154146"	"NRGN"	"hsa:4900; Q92686"	""	"Long-term potentiation"	"1"	"0"	"22.0"	"79.5"	"67.9"	"13.4"	"62.6"	"22.3"	"41.7"	"42.1"	"67.8"	"105.7"	"211.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P82912"	"28S ribosomal protein S11, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS11 PE=1 SV=2"	"9"	"1"	"1"	"1"	"194"	"20.6"	"10.81"	"567.03"	""	"1"	""	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00411"	"64963"	"ENSG00000181991"	"MRPS11"	"B2RD52; hsa:64963; P82912; Q969D7; Q96GI3; Q9BYC3"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"6.7"	"16.4"	"10.5"	"7.1"	"14.7"	"9.5"	"5.3"	"1.7"	"6.9"	"11.5"	"25.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P20290"	"Transcription factor BTF3 OS=Homo sapiens OX=9606 GN=BTF3 PE=1 SV=1"	"3"	"2"	"2"	"2"	"206"	"22.2"	"9.38"	"545.72"	""	"2"	""	"transport;developmental processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	""	"Pf01849"	"689"	"ENSG00000145741"	"BTF3"	"A8K510; hsa:689; P20290; Q13893; Q76M56"	"Orexin receptor pathway"	""	"1"	"0"	"174.5"	"350.3"	"407.8"	"119.5"	"377.2"	"194.8"	"320.7"	"210.4"	"314.1"	"330.7"	"661.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96G03"	"Phosphoglucomutase-2 OS=Homo sapiens OX=9606 GN=PGM2 PE=1 SV=4"	"1"	"1"	"2"	"1"	"612"	"68.2"	"6.73"	"534.36"	""	"1"	""	"other metabolic processes"	"non-structural extracellular;cytosol;other cell component"	"other molecular function"	"Pf00408, Pf02878, Pf02879, Pf02880"	"55276"	"ENSG00000169299"	"PGM2"	"B4E0G8; hsa:55276; Q53FP5; Q5QTR0; Q96G03; Q9H0P9; Q9NV22"	"Clear cell renal cell carcinoma pathways; Glucuronidation"	"Neutrophil degranulation; Pentose phosphate pathway"	"4"	"0"	"12.2"	"129.6"	"84.9"	"2.0"	"83.0"	"17.8"	"18.5"	"15.1"	"18.3"	"28.0"	"70.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UNZ5"	"Leydig cell tumor 10 kDa protein homolog OS=Homo sapiens OX=9606 GN=C19orf53 PE=1 SV=1"	"10"	"1"	"1"	"1"	"99"	"10.6"	"11.55"	"521.38"	""	"1"	""	""	""	""	"Pf09495"	"28974"	"ENSG00000104979"	"C19orf53"	"B2R4J9; hsa:28974; Q9UNZ5"	""	""	"0"	"0"	"4.5"	"6.9"	"8.8"	"2.4"	"8.7"	"4.3"	"63.1"	"39.7"	"56.6"	"63.6"	"93.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P56181"	"NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV3 PE=1 SV=2"	"15"	"1"	"1"	"1"	"108"	"11.9"	"9.70"	"518.97"	""	"1"	""	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf15880"	"4731"	"ENSG00000160194"	"NDUFV3"	"A8K0M1; hsa:4731; J3KNX7; P56181; Q6FGD3; Q8WU60; Q9HCR5"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"28.8"	"61.0"	"52.7"	"22.5"	"52.1"	"32.9"	"63.3"	"44.3"	"69.9"	"71.6"	"120.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75323"	"Protein NipSnap homolog 2 OS=Homo sapiens OX=9606 GN=NIPSNAP2 PE=1 SV=1"	"5"	"2"	"2"	"2"	"286"	"33.7"	"9.36"	"513.08"	""	"2"	""	"cell organization and biogenesis;other metabolic processes;other biological processes"	"other membranes;mitochondrion"	""	"Pf07978"	"2631"	"ENSG00000146729"	"NIPSNAP2"	"C9IYJ3; hsa:2631; O43801; O75323; Q53X96"	""	"RHOJ GTPase cycle; RHOH GTPase cycle"	"2"	"0"	"156.8"	"441.4"	"410.4"	"138.7"	"368.0"	"203.7"	"315.1"	"223.0"	"373.8"	"472.7"	"784.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14571"	"Inositol 1,4,5-trisphosphate receptor type 2 OS=Homo sapiens OX=9606 GN=ITPR2 PE=1 SV=2"	"0"	"2"	"2"	"1"	"2701"	"307.9"	"6.43"	"510.94"	""	"2"	""	"stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf00520, Pf01365, Pf02815, Pf08454, Pf08709"	"3709"	"ENSG00000123104"	"ITPR2"	"hsa:3709; O94773; Q14571"	"Alzheimer's disease and miRNA effects; Myometrial relaxation and contraction pathways; Vitamin D-sensitive calcium signaling in depression; Thyroid hormones production and peripheral downstream signaling effects; Alzheimer's disease; GDNF signaling; Calcium regulation in cardiac cells"	"Role of phospholipids in phagocytosis; FCERI mediated Ca+2 mobilization; FCGR3A-mediated IL10 synthesis; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Ion homeostasis; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Ca2+ pathway; VEGFR2 mediated cell proliferation; Elevation of cytosolic Ca2+ levels; PLC beta mediated events; DAG and IP3 signaling; CLEC7A (Dectin-1) induces NFAT activation; Effects of PIP2 hydrolysis"	"21"	"0"	"111.2"	"214.8"	"221.0"	"94.8"	"184.1"	"106.8"	"354.1"	"265.9"	"368.9"	"388.9"	"652.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P98175"	"RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3"	"1"	"1"	"1"	"1"	"930"	"103.5"	"5.97"	"484.99"	""	"1"	""	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00641, Pf01585, Pf17780"	"8241"	"ENSG00000182872"	"RBM10"	"A0A0A0MR66; C4AM81; hsa:8241; P98175; Q14136; Q5JRR2; Q9BTE4; Q9BTX0; Q9NTB1"	""	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43663"	"Protein regulator of cytokinesis 1 OS=Homo sapiens OX=9606 GN=PRC1 PE=1 SV=2"	"2"	"1"	"1"	"1"	"620"	"71.6"	"6.68"	"482.28"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03999"	"9055"	"ENSG00000198901"	"PRC1"	"A6NC44; B4DLR1; H9KV59; hsa:9055; O43663; Q9BSB6"	""	"RHO GTPases activate CIT"	"1"	"0"	"6.2"	"7.9"	"12.6"	"5.9"	"10.2"	"4.2"	"27.9"	"22.1"	"31.6"	"35.4"	"64.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P021"	"Cysteine-rich PDZ-binding protein OS=Homo sapiens OX=9606 GN=CRIPT PE=1 SV=1"	"12"	"1"	"2"	"1"	"101"	"11.2"	"9.47"	"477.59"	""	"1"	""	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf10235"	"9419"	"ENSG00000119878"	"CRIPT"	"hsa:9419; Q9P021"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UNE7"	"E3 ubiquitin-protein ligase CHIP OS=Homo sapiens OX=9606 GN=STUB1 PE=1 SV=2"	"4"	"1"	"1"	"1"	"303"	"34.8"	"5.87"	"476.27"	""	"1"	""	"protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf04564, Pf12895, Pf18391"	"10273"	"ENSG00000103266"	"STUB1"	"A2IDB9; hsa:10273; O60526; Q969U2; Q9HBT1; Q9UNE7"	"Androgen receptor signaling pathway; Parkin-ubiquitin proteasomal system pathway"	"Antigen processing: Ubiquitination & Proteasome degradation; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Regulation of necroptotic cell death; Downregulation of ERBB2 signaling; Regulation of TNFR1 signaling; Downregulation of TGF-beta receptor signaling"	"10"	"0"	"8.8"	"96.5"	"60.8"	"6.0"	"57.4"	"11.9"	"39.9"	"44.0"	"53.2"	"72.0"	"148.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00442"	"RNA 3'-terminal phosphate cyclase OS=Homo sapiens OX=9606 GN=RTCA PE=1 SV=1"	"3"	"1"	"1"	"1"	"366"	"39.3"	"7.85"	"475.66"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf01137, Pf05189"	"8634"	"ENSG00000137996"	"RTCA"	"hsa:8634; O00442; Q5VVL5; Q5VVL6; Q96E99"	""	""	"0"	"0"	"40.7"	"143.1"	"149.0"	"41.3"	"151.1"	"76.8"	"82.0"	"57.4"	"91.5"	"108.3"	"233.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q14061"	"Cytochrome c oxidase copper chaperone OS=Homo sapiens OX=9606 GN=COX17 PE=1 SV=2"	"25"	"1"	"1"	"1"	"63"	"6.9"	"7.24"	"447.12"	""	"1"	""	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"mitochondrion;other cell component"	"enzyme regulator activity;other molecular function"	"Pf05051"	"10063"	"ENSG00000138495"	"COX17"	"B2R5D2; D3DN84; hsa:10063; Q14061; Q3MHD6"	"Electron transport chain: OXPHOS system in mitochondria; Copper homeostasis; IL-18 signaling pathway; Mitochondrial complex IV assembly"	"Mitochondrial protein import"	"5"	"0"	"47.7"	"78.2"	"103.6"	"35.3"	"102.3"	"59.9"	"47.9"	"26.2"	"49.6"	"42.7"	"76.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q71RC2"	"La-related protein 4 OS=Homo sapiens OX=9606 GN=LARP4 PE=1 SV=3"	"2"	"1"	"1"	"1"	"724"	"80.5"	"6.61"	"439.35"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity"	"Pf05383"	"113251"	"ENSG00000161813"	"LARP4"	"A8K6T1; E9PDG5; G3XAA8; G5E976; hsa:113251; Q5CZ97; Q6ZV14; Q71RC2; Q96NF9"	""	""	"0"	"0"	"2.7"	"18.2"	"20.0"	"2.7"	"14.8"	"4.6"	"6.4"	"9.4"	"9.7"	"8.4"	"23.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15059"	"Bromodomain-containing protein 3 OS=Homo sapiens OX=9606 GN=BRD3 PE=1 SV=1"	"2"	"1"	"1"	"1"	"726"	"79.5"	"9.36"	"424.95"	""	"1"	""	"cell organization and biogenesis;other biological processes"	"nucleus"	"other molecular function"	"Pf00439, Pf17035"	"8019"	"ENSG00000169925"	"BRD3"	"B1APD9; hsa:8019; Q15059; Q4G5Y3; Q5T1R7; Q8N5M3; Q92645"	""	""	"0"	"0"	"0.0"	"5.3"	"7.4"	"0.0"	"5.9"	"0.0"	"14.3"	"10.3"	"11.7"	"24.4"	"34.3"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55084"	"Trifunctional enzyme subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=HADHB PE=1 SV=3"	"3"	"1"	"1"	"1"	"474"	"51.3"	"9.41"	"409.76"	""	"1"	""	"other metabolic processes;other biological processes"	"other membranes;mitochondrion;ER/Golgi"	"nucleic acid binding activity;other molecular function"	"Pf00108, Pf02803"	"3032"	"ENSG00000138029"	"HADHB"	"B2RB16; B4E2W0; hsa:3032; O14969; P55084; Q53TA6; Q96C77; Q9H3F5; Q9T2V8"	"Fatty acid beta-oxidation; Valproic acid pathway; Female steroid hormones in cardiomyocyte energy metabolism; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Acyl chain remodeling of CL; mitochondrial fatty acid beta-oxidation of unsaturated fatty acids; Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA; Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of myristoyl-CoA to lauroyl-CoA; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA; Beta oxidation of palmitoyl-CoA to myristoyl-CoA"	"12"	"0"	"8.5"	"16.5"	"19.3"	"7.5"	"15.6"	"11.9"	"13.9"	"12.1"	"17.1"	"24.1"	"21.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15650"	"Activating signal cointegrator 1 OS=Homo sapiens OX=9606 GN=TRIP4 PE=1 SV=4"	"3"	"1"	"1"	"1"	"581"	"66.1"	"7.85"	"390.84"	""	"1"	""	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf04266, Pf06221"	"9325"	"ENSG00000103671"	"TRIP4"	"B2RAS0; hsa:9325; Q15650; Q96ED7; Q9UKH0"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"12.3"	"21.7"	"23.5"	"11.1"	"25.2"	"17.0"	"19.9"	"17.4"	"24.6"	"41.4"	"73.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6PJT7"	"Zinc finger CCCH domain-containing protein 14 OS=Homo sapiens OX=9606 GN=ZC3H14 PE=1 SV=1"	"2"	"1"	"1"	"1"	"736"	"82.8"	"7.31"	"389.96"	""	"1"	""	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf14608"	"79882"	"ENSG00000100722"	"ZC3H14"	"A8MY46; B4DXU8; B4DZW7; B4E2H4; G3V5R4; hsa:79882; Q6MZU4; Q6PJ32; Q6PJT7; Q6PUI6; Q6PUI8; Q86TQ5; Q86TW0; Q86TW1; Q8NCT6; Q8NCZ3; Q8TDE2; Q9HAC9; Q9Y5A0"	""	""	"0"	"0"	"13.9"	"23.7"	"19.6"	"7.3"	"17.5"	"14.4"	"17.2"	"12.5"	"24.2"	"30.8"	"30.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BWJ5"	"Splicing factor 3B subunit 5 OS=Homo sapiens OX=9606 GN=SF3B5 PE=1 SV=1"	"17"	"1"	"1"	"1"	"86"	"10.1"	"6.35"	"385.82"	""	"1"	""	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf07189"	"83443"	"ENSG00000169976"	"SF3B5"	"B2R568; hsa:83443; Q7RTV1; Q9BWJ5"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"3"	"0"	"25.7"	"36.9"	"40.4"	"15.7"	"41.3"	"27.9"	"45.4"	"33.7"	"53.4"	"46.4"	"69.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15631"	"Translin OS=Homo sapiens OX=9606 GN=TSN PE=1 SV=1"	"5"	"1"	"1"	"1"	"228"	"26.2"	"6.44"	"380.31"	""	"1"	""	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01997"	"7247"	"ENSG00000211460"	"TSN"	"B7Z3X8; hsa:7247; Q15631; Q5U0K7"	""	"Small interfering RNA (siRNA) biogenesis"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y3A3"	"MOB-like protein phocein OS=Homo sapiens OX=9606 GN=MOB4 PE=1 SV=1"	"4"	"1"	"1"	"1"	"225"	"26.0"	"5.78"	"380.28"	""	"1"	""	""	"other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf03637"	"25843"	"ENSG00000115540"	"MOB4"	"B4DML0; hsa:25843; Q53SE0; Q7Z4Y6; Q9H2P3; Q9H5J1; Q9Y3A3; Q9Y4T8"	""	""	"0"	"0"	"7.7"	"53.7"	"49.7"	"9.6"	"33.5"	"12.4"	"25.8"	"23.1"	"32.3"	"73.0"	"136.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P62072"	"Mitochondrial import inner membrane translocase subunit Tim10 OS=Homo sapiens OX=9606 GN=TIMM10 PE=1 SV=1"	"16"	"1"	"1"	"1"	"90"	"10.3"	"6.29"	"373.09"	""	"1"	""	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf02953"	"26519"	"ENSG00000134809"	"TIMM10"	"A8K136; hsa:26519; P62072; Q9WV99; Q9WVA0; Q9Y5J8"	""	"Mitochondrial protein import"	"1"	"0"	"5.0"	"15.9"	"9.1"	"2.1"	"11.2"	"7.4"	"14.3"	"9.4"	"14.1"	"14.5"	"22.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P29144"	"Tripeptidyl-peptidase 2 OS=Homo sapiens OX=9606 GN=TPP2 PE=1 SV=4"	"1"	"1"	"1"	"1"	"1249"	"138.3"	"6.32"	"367.70"	""	"1"	""	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00082, Pf12580"	"7174"	"ENSG00000134900"	"TPP2"	"hsa:7174; P29144; Q5VZU8"	""	"Antigen processing: Ubiquitination & Proteasome degradation"	"1"	"0"	"12.4"	"52.2"	"45.6"	"17.8"	"51.8"	"10.7"	"27.1"	"28.6"	"42.4"	"50.8"	"86.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y6Y8"	"SEC23-interacting protein OS=Homo sapiens OX=9606 GN=SEC23IP PE=1 SV=1"	"1"	"1"	"1"	"1"	"1000"	"111.0"	"5.54"	"360.88"	""	"1"	""	"cell organization and biogenesis;transport"	"other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00536, Pf02862"	"11196"	"ENSG00000107651"	"SEC23IP"	"D3DRD2; hsa:11196; Q8IXH5; Q9BUK5; Q9Y6Y8"	""	"COPII-mediated vesicle transport"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NXX6"	"Non-structural maintenance of chromosomes element 4 homolog A OS=Homo sapiens OX=9606 GN=NSMCE4A PE=1 SV=2"	"2"	"1"	"1"	"1"	"385"	"44.3"	"5.38"	"359.31"	""	"1"	""	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	""	"Pf08743, Pf15412"	"54780"	"ENSG00000107672"	"NSMCE4A"	"hsa:54780; Q5SQQ5; Q6P673; Q8WY66; Q9BS90; Q9NXX6"	""	"SUMOylation of DNA damage response and repair proteins"	"1"	"0"	"34.1"	"63.2"	"70.7"	"32.4"	"51.2"	"43.8"	"112.1"	"87.0"	"130.6"	"164.5"	"217.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75489"	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS3 PE=1 SV=1"	"6"	"1"	"1"	"1"	"264"	"30.2"	"7.50"	"356.46"	""	"1"	""	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion;nucleus"	"transporter activity;other molecular function"	"Pf00329"	"4722"	"ENSG00000213619; ENSG00000285387"	"NDUFS3"	"B2R9J1; B4DFM8; hsa:4722; O75489; Q9UNQ8"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"RHOG GTPase cycle; Complex I biogenesis"	"6"	"0"	"4.4"	"9.9"	"14.4"	"0.0"	"9.7"	"3.3"	"5.6"	"9.3"	"15.1"	"17.1"	"28.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NUL3"	"Double-stranded RNA-binding protein Staufen homolog 2 OS=Homo sapiens OX=9606 GN=STAU2 PE=1 SV=2"	"2"	"1"	"1"	"1"	"570"	"62.6"	"9.61"	"348.43"	""	"1"	""	"stress response;transport;developmental processes;other biological processes"	"other membranes;cytoskeleton;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;translation activity;nucleic acid binding activity;other molecular function"	"Pf00035, Pf16482"	"27067"	"ENSG00000040341"	"STAU2"	"A0A0A0MTC5; B7Z1I6; B7Z292; B7Z8B4; E7ER74; E9PEI3; E9PF26; E9PF50; hsa:27067; Q6AHY7; Q96HM0; Q96HM1; Q9NUL3; Q9NVI5; Q9UGG6"	""	""	"0"	"0"	"4.8"	"12.2"	"11.8"	"6.0"	"10.3"	"4.9"	"13.2"	"8.3"	"10.3"	"14.7"	"23.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q92882"	"Osteoclast-stimulating factor 1 OS=Homo sapiens OX=9606 GN=OSTF1 PE=1 SV=2"	"6"	"1"	"1"	"1"	"214"	"23.8"	"5.68"	"344.10"	""	"1"	""	"signal transduction;other biological processes"	"other cell component"	"other molecular function"	"Pf00018, Pf12796"	"26578"	"ENSG00000134996"	"OSTF1"	"hsa:26578; Q5W126; Q92882; Q96IJ4"	""	"Neutrophil degranulation"	"1"	"0"	"3.1"	"21.5"	"15.5"	"2.6"	"20.1"	"4.5"	"6.7"	"9.1"	"11.3"	"12.3"	"17.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96B01"	"RAD51-associated protein 1 OS=Homo sapiens OX=9606 GN=RAD51AP1 PE=1 SV=1"	"3"	"1"	"1"	"1"	"352"	"38.4"	"9.11"	"342.73"	""	"1"	""	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf15696"	"10635"	"ENSG00000111247"	"RAD51AP1"	"A8K7D3; hsa:10635; O43403; Q7Z779; Q96B01"	""	"Resolution of D-loop Structures through Holliday Junction Intermediates; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Homologous DNA Pairing and Strand Exchange; Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2"	"8"	"0"	"7.8"	"27.0"	"19.7"	"6.4"	"27.6"	"6.7"	"46.6"	"45.3"	"53.4"	"82.5"	"118.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NRG9"	"Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1"	"2"	"1"	"1"	"1"	"546"	"59.5"	"7.50"	"325.23"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus"	""	"Pf00400"	"8086"	"ENSG00000094914"	"AAAS"	"hsa:8086; Q5JB47; Q9NRG9; Q9NWI6; Q9UG19"	""	"RHOA GTPase cycle; ISG15 antiviral mechanism; SARS-CoV-2 activates/modulates innate and adaptive immune responses; tRNA processing in the nucleus; SUMOylation of chromatin organization proteins; Transport of Mature mRNA derived from an Intron-Containing Transcript; HCMV Late Events; HCMV Early Events; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"	"29"	"0"	"9.8"	"41.8"	"38.2"	"6.7"	"35.5"	"13.6"	"18.8"	"18.0"	"27.2"	"35.2"	"69.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N983"	"39S ribosomal protein L43, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL43 PE=1 SV=1"	"5"	"1"	"1"	"1"	"215"	"23.4"	"8.65"	"320.58"	""	"1"	""	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf05047"	"84545"	"ENSG00000055950"	"MRPL43"	"B1AL06; B1AL07; B1AL09; B1AL10; C9J5Q3; D3DR71; hsa:84545; Q5JW06; Q7Z719; Q7Z7H6; Q86XN1; Q8N983; Q9BYC7"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"41.7"	"187.3"	"172.8"	"33.6"	"140.0"	"53.6"	"96.0"	"90.6"	"114.7"	"156.2"	"295.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75832"	"26S proteasome non-ATPase regulatory subunit 10 OS=Homo sapiens OX=9606 GN=PSMD10 PE=1 SV=1"	"4"	"1"	"1"	"1"	"226"	"24.4"	"6.10"	"320.31"	""	"1"	""	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf12796"	"5716"	"ENSG00000101843"	"PSMD10"	"hsa:5716; O75832; Q5U0B2; Q8IZK9"	"Proteasome degradation; Parkin-ubiquitin proteasomal system pathway"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"61"	"0"	"45.7"	"197.9"	"155.8"	"29.3"	"131.8"	"63.7"	"62.1"	"56.3"	"69.7"	"89.8"	"167.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6P161"	"39S ribosomal protein L54, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL54 PE=1 SV=1"	"7"	"1"	"1"	"1"	"138"	"15.8"	"9.60"	"310.50"	""	"1"	""	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf08561"	"116541"	"ENSG00000183617"	"MRPL54"	"hsa:116541; Q6P161"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"34.2"	"106.1"	"112.1"	"34.1"	"87.6"	"43.8"	"82.0"	"76.6"	"106.0"	"135.0"	"195.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9ULX3"	"RNA-binding protein NOB1 OS=Homo sapiens OX=9606 GN=NOB1 PE=1 SV=1"	"4"	"1"	"1"	"1"	"412"	"46.6"	"7.18"	"301.67"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf08772, Pf15017, Pf17146"	"28987"	"ENSG00000141101"	"NOB1"	"hsa:28987; Q7L6B7; Q7M4M4; Q7Z4B5; Q9NWB0; Q9ULX3"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"8.4"	"19.1"	"16.2"	"8.8"	"18.7"	"8.4"	"17.2"	"13.6"	"21.1"	"22.9"	"32.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75127"	"Pentatricopeptide repeat-containing protein 1, mitochondrial OS=Homo sapiens OX=9606 GN=PTCD1 PE=1 SV=2"	"2"	"1"	"1"	"1"	"700"	"78.8"	"8.59"	"301.29"	""	"1"	""	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"nucleic acid binding activity"	"Pf01535"	"26024"	"ENSG00000106246"	"PTCD1"	"hsa:26024; O75127; Q3ZB78; Q66K60; Q9UDV2"	""	""	"0"	"0"	"12.3"	"22.4"	"23.8"	"15.8"	"29.7"	"15.4"	"24.4"	"11.7"	"19.3"	"19.4"	"29.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P61019"	"Ras-related protein Rab-2A OS=Homo sapiens OX=9606 GN=RAB2A PE=1 SV=1"	"4"	"1"	"1"	"1"	"212"	"23.5"	"6.54"	"298.36"	""	"1"	""	"cell organization and biogenesis;transport"	"other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00071"	"5862"	"ENSG00000104388"	"RAB2A"	"B2R5W8; B4DMQ5; hsa:5862; P08886; P61019"	"Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Ciliary landscape"	"RAB geranylgeranylation; Golgi Cisternae Pericentriolar Stack Reorganization"	"4"	"0"	"35.1"	"245.4"	"191.7"	"28.8"	"154.5"	"50.5"	"76.7"	"66.1"	"127.3"	"141.8"	"275.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86XI2"	"Condensin-2 complex subunit G2 OS=Homo sapiens OX=9606 GN=NCAPG2 PE=1 SV=1"	"1"	"1"	"1"	"1"	"1143"	"130.9"	"6.87"	"289.12"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf12422"	"54892"	"ENSG00000146918"	"NCAPG2"	"A4D228; hsa:54892; Q7Z3J9; Q86XI2; Q8WUG8; Q9BRX6; Q9H8S2; Q9H9K6"	"Mesodermal commitment pathway"	"Condensation of Prophase Chromosomes"	"2"	"0"	"49.8"	"77.4"	"85.8"	"43.3"	"100.0"	"50.3"	"93.7"	"76.6"	"121.8"	"164.2"	"290.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15008"	"26S proteasome non-ATPase regulatory subunit 6 OS=Homo sapiens OX=9606 GN=PSMD6 PE=1 SV=1"	"2"	"1"	"1"	"1"	"389"	"45.5"	"5.62"	"287.32"	""	"1"	""	"protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	""	"Pf01399, Pf10602"	"9861"	"ENSG00000163636"	"PSMD6"	"A8K2E0; E9PHI9; hsa:9861; Q15008; Q6UV22"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"AUF1 (hnRNP D0) binds and destabilizes mRNA; Regulation of expression of SLITs and ROBOs; ABC-family proteins mediated transport; Neutrophil degranulation; Ub-specific processing proteases; Separation of Sister Chromatids; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"64"	"0"	"132.1"	"361.0"	"343.7"	"129.7"	"295.7"	"139.1"	"203.8"	"159.6"	"263.2"	"296.8"	"568.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H6R0"	"ATP-dependent RNA helicase DHX33 OS=Homo sapiens OX=9606 GN=DHX33 PE=1 SV=2"	"2"	"1"	"1"	"1"	"707"	"78.8"	"8.91"	"286.51"	""	"1"	""	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"56919"	"ENSG00000005100"	"DHX33"	"B4DHF9; hsa:56919; Q4G149; Q5CZ73; Q9H5M9; Q9H6R0"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96I99"	"Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLG2 PE=1 SV=2"	"2"	"1"	"1"	"1"	"432"	"46.5"	"6.39"	"286.08"	""	"1"	""	"other metabolic processes"	"plasma membrane;other membranes;mitochondrion;other cell component"	"other molecular function"	"Pf00549, Pf08442"	"8801"	"ENSG00000172340"	"SUCLG2"	"C9JVT2; hsa:8801; O95195; Q6NUH7; Q86VX8; Q8WUQ1; Q96I99"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Metabolic reprogramming in colon cancer; TCA cycle (aka Krebs or citric acid cycle)"	"Citric acid cycle (TCA cycle)"	"4"	"0"	"20.4"	"159.0"	"123.1"	"10.1"	"87.0"	"28.4"	"40.2"	"34.5"	"27.2"	"46.8"	"115.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P26038"	"Moesin OS=Homo sapiens OX=9606 GN=MSN PE=1 SV=3"	"2"	"1"	"1"	"1"	"577"	"67.8"	"6.40"	"285.59"	""	"1"	""	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00373, Pf00769, Pf09379, Pf09380, Pf20492"	"4478"	"ENSG00000147065"	"MSN"	"hsa:4478; P26038"	"Glial cell differentiation; AGE/RAGE pathway; Measles virus infection; 16p11.2 proximal deletion syndrome; Regulation of actin cytoskeleton"	"Recycling pathway of L1; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Signaling by ALK fusions and activated point mutants"	"10"	"0"	"14.1"	"17.9"	"23.9"	"12.2"	"26.0"	"15.5"	"37.6"	"33.2"	"55.3"	"84.2"	"131.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P05109"	"Protein S100-A8 OS=Homo sapiens OX=9606 GN=S100A8 PE=1 SV=1"	"8"	"1"	"1"	"1"	"93"	"10.8"	"7.03"	"281.87"	""	"1"	""	"cell adhesion;cell-cell signaling;protein metabolism;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf01023"	"6279"	"ENSG00000143546"	"S100A8"	"A8K5L3; D3DV37; hsa:6279; P05109; Q5SY70; Q9UC84; Q9UC92; Q9UCJ0; Q9UCM6"	"Vitamin D receptor pathway"	"Neutrophil degranulation; ER-Phagosome pathway; MyD88:MAL(TIRAP) cascade initiated on plasma membrane; MyD88 deficiency (TLR2/4); IRAK4 deficiency (TLR2/4); Regulation of TLR by endogenous ligand; Metal sequestration by antimicrobial proteins; RHO GTPases Activate NADPH Oxidases"	"9"	"0"	"81.4"	"218.3"	"374.2"	"53.1"	"122.6"	"64.4"	"138.4"	"117.7"	"158.8"	"159.7"	"192.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9Y5P6"	"Mannose-1-phosphate guanyltransferase beta OS=Homo sapiens OX=9606 GN=GMPPB PE=1 SV=2"	"3"	"1"	"1"	"1"	"360"	"39.8"	"6.61"	"279.07"	""	"1"	""	"protein metabolism;other metabolic processes"	"other cell component"	"other molecular function"	"Pf00132, Pf00483"	"29925"	"ENSG00000173540"	"GMPPB"	"A8K6N5; hsa:29925; Q9H7U3; Q9Y5P6"	"N-glycan biosynthesis"	"Synthesis of GDP-mannose"	"2"	"0"	"15.7"	"47.9"	"38.6"	"17.8"	"38.7"	"13.4"	"28.5"	"20.8"	"31.5"	"37.5"	"63.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BT43"	"DNA-directed RNA polymerase III subunit RPC7-like OS=Homo sapiens OX=9606 GN=POLR3GL PE=1 SV=1"	"3"	"1"	"1"	"1"	"218"	"25.3"	"4.54"	"278.95"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	""	"Pf11705"	"84265"	"ENSG00000121851"	"POLR3GL"	"B1MVG5; hsa:84265; Q9BT43"	"Pyrimidine metabolism; Cytosolic DNA-sensing pathway"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation"	"9"	"0"	"14.8"	"44.8"	"58.2"	"12.2"	"42.6"	"14.6"	"38.2"	"27.3"	"52.5"	"76.7"	"121.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z6R9"	"Transcription factor AP-2-delta OS=Homo sapiens OX=9606 GN=TFAP2D PE=1 SV=1"	"2"	"1"	"1"	"1"	"452"	"49.5"	"8.16"	"278.09"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03299"	"83741"	"ENSG00000008197"	"TFAP2D"	"hsa:83741; Q7Z6R9; Q8IWX0"	"Ciliary landscape"	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors; Activation of the TFAP2 (AP-2) family of transcription factors"	"3"	"0"	"195.7"	"317.9"	"905.9"	"128.1"	"131.7"	"151.9"	"238.8"	"346.6"	"588.4"	"503.4"	"424.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9ULD2"	"Microtubule-associated tumor suppressor 1 OS=Homo sapiens OX=9606 GN=MTUS1 PE=1 SV=2"	"1"	"1"	"1"	"1"	"1270"	"141.3"	"7.50"	"277.87"	""	"1"	""	"other biological processes"	"plasma membrane;other membranes;cytoskeleton;mitochondrion;ER/Golgi;nucleus"	"cytoskeletal activity"	""	"57509"	"ENSG00000129422"	"MTUS1"	"A8K135; B2RBJ6; B3KWJ9; B4DH03; B9EGA1; D3DSP8; hsa:57509; Q63HJ6; Q659F4; Q6PK49; Q6URW7; Q8N4M6; Q8WTT9; Q9H7T2; Q9ULD2"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55145"	"Mesencephalic astrocyte-derived neurotrophic factor OS=Homo sapiens OX=9606 GN=MANF PE=1 SV=3"	"4"	"1"	"1"	"1"	"182"	"20.7"	"8.69"	"276.47"	""	"1"	""	"cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf10208, Pf20145"	"7873"	"ENSG00000145050"	"MANF"	"hsa:7873; P55145; Q14CX4; Q86U67; Q96IS4"	"Orexin receptor pathway"	"Platelet degranulation"	"2"	"0"	"0.0"	"12.5"	"9.5"	"5.3"	"5.7"	"6.8"	"8.4"	"18.6"	"16.2"	"27.5"	"43.7"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60341"	"Lysine-specific histone demethylase 1A OS=Homo sapiens OX=9606 GN=KDM1A PE=1 SV=2"	"2"	"1"	"1"	"1"	"852"	"92.8"	"6.52"	"274.60"	""	"1"	""	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01593, Pf04433"	"23028"	"ENSG00000004487"	"KDM1A"	"A8MWP9; hsa:23028; O60341; Q5TH94; Q5TH95; Q86VT7; Q8IXK4; Q8NDP6; Q8TAZ3; Q96AW4"	"Androgen receptor signaling pathway; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; Thermogenesis; Vitamin D-sensitive calcium signaling in depression; Thyroid hormones production and peripheral downstream signaling effects; Neurogenesis regulation in the olfactory epithelium"	"Estrogen-dependent gene expression; Potential therapeutics for SARS; Regulation of PTEN gene transcription; HDACs deacetylate histones; Factors involved in megakaryocyte development and platelet production; HDMs demethylate histones; NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3"	"14"	"0"	"23.9"	"95.4"	"93.4"	"17.9"	"65.8"	"29.5"	"45.4"	"34.0"	"51.1"	"57.5"	"116.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NEK5"	"Zinc finger protein 548 OS=Homo sapiens OX=9606 GN=ZNF548 PE=1 SV=2"	"1"	"1"	"1"	"1"	"533"	"62.7"	"8.03"	"274.09"	""	"1"	""	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00096, Pf01352"	"147694"	"ENSG00000188785"	"ZNF548"	"hsa:147694; Q8NEK5; Q96M05"	""	"Generic Transcription Pathway"	"1"	"0"	"174.1"	"306.5"	"559.5"	"136.4"	"300.9"	"176.2"	"341.4"	"266.6"	"362.5"	"384.6"	"596.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NCW5"	"NAD(P)H-hydrate epimerase OS=Homo sapiens OX=9606 GN=NAXE PE=1 SV=2"	"3"	"1"	"1"	"1"	"288"	"31.7"	"7.66"	"273.15"	""	"1"	""	"cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"non-structural extracellular;mitochondrion;other cell component"	"other molecular function"	"Pf03853"	"128240"	"ENSG00000163382"	"NAXE"	"B4DGY3; hsa:128240; Q496C6; Q5T3I2; Q8NCW5"	""	"Nicotinamide salvaging"	"1"	"0"	"67.6"	"319.2"	"271.6"	"32.7"	"233.6"	"82.2"	"119.2"	"95.3"	"114.3"	"178.3"	"324.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13308"	"Inactive tyrosine-protein kinase 7 OS=Homo sapiens OX=9606 GN=PTK7 PE=1 SV=2"	"1"	"1"	"1"	"1"	"1070"	"118.3"	"7.09"	"272.44"	""	"1"	""	"cell adhesion;cell-cell signaling;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"kinase activity;other molecular function"	"Pf07679, Pf07714, Pf13927"	"5754"	"ENSG00000112655"	"PTK7"	"A8K974; B7Z477; E9PFZ5; hsa:5754; Q13308; Q13417; Q5T650; Q6IQ54; Q8NFA5; Q8NFA6; Q8NFA7; Q8NFA8"	""	""	"0"	"0"	"3.5"	"20.6"	"15.6"	"1.5"	"13.6"	"2.8"	"8.9"	"7.3"	"9.1"	"8.0"	"23.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75534"	"Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2"	"1"	"1"	"1"	"1"	"798"	"88.8"	"6.25"	"271.64"	""	"1"	""	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"nucleic acid binding activity"	"Pf00313, Pf12901"	"7812"	"ENSG00000009307"	"CSDE1"	"A8K281; E9PGZ0; G5E9Q2; hsa:7812; O75534; O94961; Q5TF04; Q5TF05; Q68DF1; Q68DI9; Q9Y2S4"	""	""	"0"	"0"	"36.8"	"194.3"	"162.4"	"30.2"	"127.1"	"51.4"	"103.3"	"96.7"	"140.6"	"252.1"	"508.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00423"	"Echinoderm microtubule-associated protein-like 1 OS=Homo sapiens OX=9606 GN=EML1 PE=1 SV=3"	"1"	"1"	"1"	"1"	"815"	"89.8"	"7.06"	"268.33"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400, Pf03451"	"2009"	"ENSG00000066629"	"EML1"	"hsa:2009; O00423; Q86U15; Q8N536; Q8N5C4; Q8WWL6"	""	""	"0"	"0"	"49.0"	"70.2"	"86.1"	"49.9"	"80.7"	"61.2"	"86.7"	"87.2"	"127.2"	"198.8"	"277.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TDD1"	"ATP-dependent RNA helicase DDX54 OS=Homo sapiens OX=9606 GN=DDX54 PE=1 SV=2"	"1"	"1"	"1"	"1"	"881"	"98.5"	"10.02"	"266.64"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes;signal transduction"	"ER/Golgi;nucleus"	"signal transduction activity or receptor binding;other molecular function"	"Pf00270, Pf00271, Pf08147"	"79039"	"ENSG00000123064"	"DDX54"	"hsa:79039; Q86YT8; Q8TDD1; Q9BRZ1"	""	""	"0"	"0"	"3.8"	"8.6"	"12.7"	"4.2"	"8.9"	"10.8"	"12.8"	"8.2"	"11.2"	"17.1"	"23.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75391"	"Sperm-associated antigen 7 OS=Homo sapiens OX=9606 GN=SPAG7 PE=1 SV=2"	"3"	"1"	"1"	"1"	"227"	"26.0"	"7.91"	"266.21"	""	"1"	""	""	"nucleus"	"nucleic acid binding activity"	"Pf01424"	"9552"	"ENSG00000091640"	"SPAG7"	"hsa:9552; O75391; Q96EU5"	""	""	"0"	"0"	"126.5"	"188.2"	"219.4"	"113.4"	"200.7"	"137.1"	"229.2"	"132.2"	"237.2"	"286.9"	"454.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P30519"	"Heme oxygenase 2 OS=Homo sapiens OX=9606 GN=HMOX2 PE=1 SV=2"	"3"	"1"	"1"	"1"	"316"	"36.0"	"5.41"	"264.87"	""	"1"	""	"other metabolic processes;stress response"	"plasma membrane;other membranes;ER/Golgi"	"other molecular function"	"Pf01126"	"3163"	"ENSG00000103415; ENSG00000277424"	"HMOX2"	"A8MT35; D3DUD5; hsa:3163; I3L430; O60605; P30519"	""	"Neutrophil degranulation; Cytoprotection by HMOX1; RHOA GTPase cycle; Iron uptake and transport; Heme degradation"	"5"	"0"	"22.1"	"62.9"	"54.5"	"20.8"	"65.3"	"17.7"	"31.3"	"18.7"	"25.0"	"25.2"	"70.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NX07"	"tRNA selenocysteine 1-associated protein 1 OS=Homo sapiens OX=9606 GN=TRNAU1AP PE=1 SV=1"	"2"	"1"	"1"	"1"	"287"	"32.5"	"4.74"	"264.50"	""	"1"	""	"protein metabolism;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf17654"	"54952"	"ENSG00000180098"	"TRNAU1AP"	"hsa:54952; Q86SU7; Q9NX07"	""	""	"0"	"0"	"12.3"	"33.5"	"27.9"	"10.7"	"22.7"	"13.4"	"15.7"	"19.7"	"18.4"	"22.9"	"32.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H2P0"	"Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1"	"1"	"1"	"1"	"1"	"1102"	"123.5"	"7.34"	"262.46"	""	"1"	""	"cell organization and biogenesis;RNA metabolism OR transcription;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00046, Pf19627"	"23394"	"ENSG00000101126"	"ADNP"	"E1P5Y2; hsa:23394; O94881; Q5BKU2; Q9H2P0; Q9UG34"	""	""	"0"	"0"	"62.1"	"115.7"	"113.9"	"39.7"	"116.5"	"54.8"	"231.6"	"323.3"	"714.9"	"1087.2"	"1905.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60524"	"Nuclear export mediator factor NEMF OS=Homo sapiens OX=9606 GN=NEMF PE=1 SV=4"	"1"	"1"	"1"	"1"	"1076"	"122.9"	"6.35"	"260.68"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport"	"cytosol;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf05670, Pf05833, Pf11923"	"9147"	"ENSG00000165525"	"NEMF"	"A0JLQ3; B3KSK1; B4DDL3; B4DHA9; B4E3F3; hsa:9147; O60524; Q32Q66; Q8WW70; Q9NWG1"	""	""	"0"	"0"	"7.0"	"27.2"	"43.6"	"6.5"	"43.3"	"10.3"	"41.0"	"24.6"	"30.4"	"36.7"	"44.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P2D0"	"Inhibitor of Bruton tyrosine kinase OS=Homo sapiens OX=9606 GN=IBTK PE=1 SV=3"	"1"	"1"	"1"	"1"	"1353"	"150.4"	"7.71"	"259.22"	""	"1"	""	"transport;other biological processes"	"other membranes;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00415, Pf00651, Pf12796"	"25998"	"ENSG00000005700; ENSG00000283068"	"IBTK"	"hsa:25998; Q2QKU2; Q2QKU3; Q2QKU4; Q5TFD7; Q5TFD9; Q8IUQ9; Q8IUY7; Q8TAI4; Q9HBI8; Q9P2D0; Q9Y3T8"	"Genetic causes of porto-sinusoidal vascular disease"	""	"1"	"0"	"3.3"	"9.0"	"8.6"	"3.1"	"12.0"	"5.0"	"23.5"	"15.7"	"24.8"	"47.9"	"70.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5VSY0"	"G kinase-anchoring protein 1 OS=Homo sapiens OX=9606 GN=GKAP1 PE=1 SV=2"	"2"	"1"	"1"	"1"	"366"	"42.1"	"8.82"	"256.70"	""	"1"	""	"signal transduction;other biological processes"	"ER/Golgi"	"other molecular function"	""	"80318"	"ENSG00000165113"	"GKAP1"	"hsa:80318; Q5VSY0; Q96LI0; Q9BYI1; Q9BYI2; Q9H225"	""	""	"0"	"0"	"14.5"	"31.0"	"27.2"	"7.3"	"18.8"	"11.9"	"19.0"	"21.6"	"29.1"	"46.4"	"74.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q969H8"	"Myeloid-derived growth factor OS=Homo sapiens OX=9606 GN=MYDGF PE=1 SV=1"	"3"	"1"	"1"	"1"	"173"	"18.8"	"6.68"	"256.46"	""	"1"	""	"developmental processes;other biological processes"	"non-structural extracellular;ER/Golgi"	""	"Pf10572"	"56005"	"ENSG00000074842"	"MYDGF"	"D6W628; hsa:56005; O75256; O75272; Q969H8; Q9BTK7; Q9NP69"	""	"XBP1(S) activates chaperone genes"	"1"	"0"	"29.6"	"503.9"	"364.3"	"0.0"	"262.1"	"44.6"	"100.6"	"68.6"	"87.4"	"128.1"	"341.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HCY8"	"Protein S100-A14 OS=Homo sapiens OX=9606 GN=S100A14 PE=1 SV=1"	"7"	"1"	"1"	"1"	"104"	"11.7"	"5.24"	"256.38"	""	"1"	""	"stress response;signal transduction;other biological processes"	"non-structural extracellular;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01023"	"57402"	"ENSG00000189334"	"S100A14"	"hsa:57402; Q5RHT0; Q9HCY8"	""	""	"0"	"0"	"89.6"	"146.0"	"172.6"	"78.2"	"143.4"	"89.8"	"146.3"	"147.2"	"191.8"	"212.8"	"280.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H4A4"	"Aminopeptidase B OS=Homo sapiens OX=9606 GN=RNPEP PE=1 SV=2"	"2"	"1"	"1"	"1"	"650"	"72.5"	"5.74"	"256.08"	""	"1"	""	"protein metabolism"	"non-structural extracellular;plasma membrane;other membranes"	"other molecular function"	"Pf01433, Pf09127, Pf17900"	"6051"	"ENSG00000176393"	"RNPEP"	"hsa:6051; Q9BVM9; Q9H1D4; Q9H4A4; Q9NPT7"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86UK0"	"ATP-binding cassette sub-family A member 12 OS=Homo sapiens OX=9606 GN=ABCA12 PE=1 SV=3"	"0"	"1"	"1"	"1"	"2595"	"293.0"	"7.75"	"255.52"	""	"1"	""	"cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;transporter activity;other molecular function"	"Pf00005, Pf12698"	"26154"	"ENSG00000144452"	"ABCA12"	"hsa:26154; Q53QE2; Q53S55; Q86UK0; Q8IZW6; Q96JT3; Q9Y4M5"	""	"ABC transporters in lipid homeostasis; Defective ABCA12 causes ARCI4B"	"2"	"0"	"42.0"	"181.9"	"165.3"	"33.4"	"116.4"	"44.3"	"113.3"	"98.5"	"158.0"	"198.2"	"331.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96A33"	"Coiled-coil domain-containing protein 47 OS=Homo sapiens OX=9606 GN=CCDC47 PE=1 SV=1"	"1"	"1"	"1"	"1"	"483"	"55.8"	"4.87"	"255.33"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;other cell component"	"translation activity;other molecular function"	"Pf07946"	"57003"	"ENSG00000108588"	"CCDC47"	"B2RAS8; D3DU20; hsa:57003; Q96A33; Q96D00; Q96JZ7; Q9H3E4; Q9NRG3"	""	""	"0"	"0"	"62.1"	"121.6"	"127.3"	"55.4"	"127.6"	"56.3"	"121.0"	"88.3"	"126.7"	"176.0"	"304.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BWF3"	"RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1"	"2"	"1"	"1"	"1"	"364"	"40.3"	"7.08"	"255.12"	""	"1"	""	"cell-cell signaling;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00098"	"5936"	"ENSG00000173933"	"RBM4"	"B3KUN0; B4E1U0; E7EQS3; hsa:5936; O02916; Q4VC48; Q6P1P2; Q8WU85; Q9BWF3"	""	"Circadian Clock"	"1"	"0"	"27.8"	"90.6"	"84.0"	"34.6"	"92.8"	"43.1"	"61.0"	"51.7"	"74.2"	"96.0"	"151.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O75170"	"Serine/threonine-protein phosphatase 6 regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PPP6R2 PE=1 SV=2"	"1"	"1"	"1"	"1"	"966"	"104.9"	"4.87"	"255.06"	""	"1"	""	"other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf04499"	"9701"	"ENSG00000100239"	"PPP6R2"	"A6PVG3; B7Z7T3; hsa:9701; O75170; Q5U5P3; Q7Z2L2; Q7Z5G5; Q7Z731; Q9UGB9"	""	""	"0"	"0"	"4.1"	"20.6"	"18.8"	"2.5"	"14.3"	"5.2"	"8.8"	"9.2"	"9.6"	"14.1"	"21.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NYC9"	"Dynein heavy chain 9, axonemal OS=Homo sapiens OX=9606 GN=DNAH9 PE=1 SV=3"	"0"	"1"	"1"	"1"	"4486"	"511.6"	"5.91"	"255.04"	""	"1"	""	"cell organization and biogenesis;transport;other biological processes"	"non-structural extracellular;cytoskeleton"	"cytoskeletal activity;other molecular function"	"Pf03028, Pf08385, Pf08393, Pf12774, Pf12775, Pf12777, Pf12780, Pf12781, Pf17852, Pf17857, Pf18198, Pf18199"	"1770"	"ENSG00000007174"	"DNAH9"	"A2VCQ8; hsa:1770; O15064; O95494; Q9NQ28; Q9NYC9"	""	""	"0"	"0"	"89.5"	"353.2"	"288.8"	"102.4"	"238.4"	"100.9"	"82.3"	"43.6"	"57.8"	"117.1"	"254.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15398"	"Disks large-associated protein 5 OS=Homo sapiens OX=9606 GN=DLGAP5 PE=1 SV=2"	"1"	"1"	"1"	"1"	"846"	"95.1"	"9.00"	"254.65"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf03359"	"9787"	"ENSG00000126787"	"DLGAP5"	"A8MTM6; B4DRM8; hsa:9787; Q15398; Q86T11; Q8NG58"	"Complement system in neuronal development and plasticity"	"NOTCH3 Intracellular Domain Regulates Transcription"	"2"	"0"	"30.5"	"78.9"	"85.1"	"30.8"	"84.3"	"41.3"	"73.3"	"56.1"	"89.8"	"125.0"	"178.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P04637"	"Cellular tumor antigen p53 OS=Homo sapiens OX=9606 GN=TP53 PE=1 SV=4"	"2"	"1"	"1"	"1"	"393"	"43.6"	"6.79"	"254.39"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00870, Pf07710, Pf08563, Pf18521"	"7157"	"ENSG00000141510"	"TP53"	"hsa:7157; P04637; Q15086; Q15087; Q15088; Q16535; Q16807; Q16808; Q16809; Q16810; Q16811; Q16848; Q2XN98; Q3LRW1; Q3LRW2; Q3LRW3; Q3LRW4; Q3LRW5; Q86UG1; Q8J016; Q99659; Q9BTM4; Q9HAQ8; Q9NP68; Q9NPJ2; Q9NZD0; Q9UBI2; Q9UQ61"	"AMP-activated protein kinase signaling; miRNA regulation of DNA damage response; miRNAs involved in DNA damage response; Fluoropyrimidine activity; TP53 network; Folate metabolism; Apoptosis modulation and signaling; Cell cycle; Metastatic brain tumor; Glioblastoma signaling pathways; Gastric cancer network 2; Oncostatin M signaling pathway; Spinal cord injury; Retinoblastoma gene in cancer; Amyotrophic lateral sclerosis (ALS); ATM signaling pathway; Apoptosis; Mammary gland development pathway - Involution (Stage 4 of 4); Bladder cancer; Copper homeostasis; RAC1/PAK1/p38/MMP2 pathway; Photodynamic therapy-induced HIF-1 survival signaling; Hepatitis C and hepatocellular carcinoma; Pathways affected in adenoid cystic carcinoma; lncRNA-mediated mechanisms of therapeutic resistance; MAPK signaling pathway; miRNA regulation of p53 pathway in prostate cancer; Wnt signaling pathway and pluripotency; Endometrial cancer; PI3K-Akt signaling pathway; Caloric restriction and aging; Chromosomal and microsatellite instability in colorectal cancer ; Epithelial to mesenchymal transition in colorectal cancer; Non-small cell lung cancer; Breast cancer pathway; Pancreatic adenocarcinoma pathway; Ultraconserved region 339 modulation of tumor suppressor microRNAs in cancer; Ferroptosis; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; MicroRNA network associated with chronic lymphocytic leukemia; G1 to S cell cycle control; Measles virus infection; 22q11.2 copy number variation syndrome; Small cell lung cancer; Head and neck squamous cell carcinoma; Melanoma; Thyroid hormones production and peripheral downstream signaling effects; Netrin-UNC5B signaling pathway; IL-18 signaling pathway; Unfolded protein response; 16p11.2 proximal deletion syndrome; Pentose phosphate pathway in senescent cells; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Glycolysis in senescence; TCA cycle in senescence; Pleural mesothelioma; Lipid metabolism in senescent cells; DYRK1A involvement regarding cell proliferation in brain development; 2q37 copy number variation syndrome; Autophagy in pancreatic ductal adenocarcinoma; 11p11.2 copy number variation syndrome ; A network map of Macrophage-stimulating protein (MSP) signaling; ErbB signaling pathway; DNA damage response; DNA damage response (only ATM dependent)"	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; TP53 Regulates Transcription of DNA Repair Genes; Regulation of PTEN gene transcription; Factors involved in megakaryocyte development and platelet production; TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest; Autodegradation of the E3 ubiquitin ligase COP1; Ub-specific processing proteases; The role of GTSE1 in G2/M progression after G2 checkpoint; TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain; Regulation of TP53 Degradation; TP53 Regulates Transcription of Death Receptors and Ligands; Oxidative Stress Induced Senescence; Regulation of TP53 Activity through Phosphorylation; TP53 Regulates Metabolic Genes; Association of TriC/CCT with target proteins during biosynthesis; Interleukin-4 and Interleukin-13 signaling; Pre-NOTCH Transcription and Translation; Oncogene Induced Senescence; Transcriptional Regulation by VENTX; TP53 Regulates Transcription of Caspase Activators and Caspases; Regulation of TP53 Activity through Methylation; G2/M DNA damage checkpoint; Regulation of NF-kappa B signaling; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Activation of PUMA and translocation to mitochondria; TP53 Regulates Transcription of Genes Involved in Cytochrome C Release; TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain; Regulation of TP53 Activity through Association with Co-factors; Ovarian tumor domain proteases; Pyroptosis; SUMOylation of transcription factors; Regulation of TP53 Expression; RUNX3 regulates CDKN1A transcription; Activation of NOXA and translocation to mitochondria; Formation of Senescence-Associated Heterochromatin Foci (SAHF); PI5P Regulates TP53 Acetylation; Transcriptional  activation of  cell cycle inhibitor p21 ; Loss of function of TP53 in cancer due to loss of tetramerization ability"	"107"	"0"	"34.6"	"97.5"	"80.5"	"25.0"	"72.5"	"40.0"	"64.6"	"66.6"	"80.9"	"112.9"	"143.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51970"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 OS=Homo sapiens OX=9606 GN=NDUFA8 PE=1 SV=3"	"3"	"1"	"1"	"1"	"172"	"20.1"	"7.65"	"254.01"	""	"1"	""	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf06747"	"4702"	"ENSG00000119421"	"NDUFA8"	"B1AM93; hsa:4702; P51970; Q9Y6N0"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"40.0"	"98.6"	"80.2"	"26.8"	"81.9"	"45.7"	"59.0"	"44.7"	"72.5"	"90.3"	"156.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z5R6"	"Amyloid beta A4 precursor protein-binding family B member 1-interacting protein OS=Homo sapiens OX=9606 GN=APBB1IP PE=1 SV=1"	"1"	"1"	"1"	"1"	"666"	"73.1"	"5.59"	"254.01"	""	"1"	""	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	""	"Pf00169, Pf00788"	"54518"	"ENSG00000077420"	"APBB1IP"	"hsa:54518; Q7Z5R6; Q8IWS8; Q8IYL7; Q8IZZ7"	"TYROBP causal network in microglia"	"Signaling by BRAF and RAF1 fusions; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; GRB2:SOS provides linkage to MAPK signaling for Integrins ; p130Cas linkage to MAPK signaling for integrins"	"11"	"0"	"248.4"	"263.0"	"345.9"	"218.8"	"357.4"	"248.4"	"219.7"	"136.0"	"201.6"	"267.0"	"312.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O60244"	"Mediator of RNA polymerase II transcription subunit 14 OS=Homo sapiens OX=9606 GN=MED14 PE=1 SV=2"	"0"	"1"	"1"	"1"	"1454"	"160.5"	"8.73"	"253.97"	""	"1"	""	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf08638"	"9282"	"ENSG00000180182"	"MED14"	"hsa:9282; O60244; Q4KMR7; Q9UNB3"	"Vitamin D in inflammatory diseases"	"PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; Generic Transcription Pathway"	"4"	"0"	"22.4"	"99.1"	"89.3"	"16.8"	"72.1"	"30.9"	"36.6"	"24.0"	"37.4"	"49.3"	"95.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8NHZ8"	"Anaphase-promoting complex subunit CDC26 OS=Homo sapiens OX=9606 GN=CDC26 PE=1 SV=1"	"14"	"1"	"1"	"1"	"85"	"9.8"	"6.81"	"252.82"	""	"1"	""	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus"	""	"Pf10471"	"246184"	"ENSG00000176386"	"CDC26"	"hsa:246184; Q8NHZ8"	""	"Assembly of the pre-replicative complex; Separation of Sister Chromatids; Antigen processing: Ubiquitination & Proteasome degradation; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; CDK-mediated phosphorylation and removal of Cdc6; Autodegradation of Cdh1 by Cdh1:APC/C; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of Cyclin B; Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase; Regulation of APC/C activators between G1/S and early anaphase; Phosphorylation of the APC/C; APC-Cdc20 mediated degradation of Nek2A; Senescence-Associated Secretory Phenotype (SASP); Transcriptional Regulation by VENTX; Aberrant regulation of mitotic exit in cancer due to RB1 defects"	"18"	"0"	"15.5"	"28.6"	"39.9"	"13.8"	"37.8"	"21.2"	"26.0"	"25.9"	"30.6"	"47.4"	"60.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9P032"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 OS=Homo sapiens OX=9606 GN=NDUFAF4 PE=1 SV=1"	"3"	"1"	"1"	"1"	"175"	"20.3"	"8.82"	"252.72"	""	"1"	""	"cell organization and biogenesis;stress response;other biological processes"	"other membranes;cytosol;mitochondrion"	"other molecular function"	"Pf06784"	"29078"	"ENSG00000123545"	"NDUFAF4"	"B2R4J5; hsa:29078; Q9P032"	""	"Complex I biogenesis"	"1"	"0"	"18.6"	"101.4"	"81.9"	"16.1"	"68.8"	"29.7"	"30.4"	"26.2"	"39.5"	"46.3"	"83.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7L8A9"	"Tubulinyl-Tyr carboxypeptidase 1 OS=Homo sapiens OX=9606 GN=VASH1 PE=1 SV=1"	"3"	"1"	"1"	"1"	"365"	"40.9"	"9.48"	"252.61"	""	"1"	""	"cell cycle OR cell proliferation;protein metabolism;stress response;developmental processes;other biological processes"	"non-structural extracellular;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf14822"	"22846"	"ENSG00000071246"	"VASH1"	"hsa:22846; Q7L8A9; Q96H02; Q9UBF4; Q9Y629"	""	"Carboxyterminal post-translational modifications of tubulin"	"1"	"0"	"36.7"	"110.2"	"105.7"	"50.0"	"100.0"	"50.4"	"154.2"	"122.1"	"192.2"	"256.6"	"434.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00410"	"Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4"	"1"	"1"	"1"	"1"	"1097"	"123.6"	"4.94"	"252.54"	""	"1"	""	"transport;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02985, Pf18808, Pf18816, Pf18829"	"3843"	"ENSG00000065150"	"IPO5"	"B4DZA0; hsa:3843; O00410; O15257; Q5T578; Q86XC7"	""	"vRNP Assembly"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86XA9"	"HEAT repeat-containing protein 5A OS=Homo sapiens OX=9606 GN=HEATR5A PE=1 SV=2"	"0"	"1"	"1"	"1"	"2040"	"221.9"	"6.58"	"252.52"	""	"1"	""	"transport;other biological processes"	"cytosol;other cell component"	""	"Pf20210"	"25938"	"ENSG00000129493"	"HEATR5A"	"hsa:25938; Q68DD8; Q6P3S5; Q6P5R9; Q86XA9; Q9H8D7; Q9NXB7; Q9P2N0; Q9UFQ3"	""	""	"0"	"0"	"18.6"	"58.0"	"47.9"	"13.2"	"34.7"	"21.5"	"38.9"	"28.2"	"27.0"	"43.6"	"75.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7Z2T5"	"TRMT1-like protein OS=Homo sapiens OX=9606 GN=TRMT1L PE=1 SV=2"	"1"	"1"	"1"	"1"	"733"	"81.7"	"7.88"	"252.18"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf02005"	"81627"	"ENSG00000121486"	"TRMT1L"	"hsa:81627; Q5TEN0; Q6ZMX0; Q7Z2T5; Q8IWH5; Q8NC68; Q9BZQ1"	""	""	"0"	"0"	"87.8"	"176.3"	"174.4"	"72.8"	"176.3"	"99.2"	"211.3"	"143.7"	"209.7"	"218.4"	"322.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q3ZCQ8"	"Mitochondrial import inner membrane translocase subunit TIM50 OS=Homo sapiens OX=9606 GN=TIMM50 PE=1 SV=2"	"2"	"1"	"1"	"1"	"353"	"39.6"	"8.37"	"252.03"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;signal transduction"	"other membranes;mitochondrion;nucleus"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf03031"	"92609"	"ENSG00000105197"	"TIMM50"	"hsa:92609; Q330K1; Q3ZCQ8; Q6QA00; Q96FJ5; Q96GY2; Q9H370"	""	"Mitochondrial protein import"	"1"	"0"	"68.7"	"309.5"	"268.0"	"54.4"	"215.4"	"64.5"	"124.8"	"103.1"	"148.8"	"219.9"	"360.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O00443"	"Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens OX=9606 GN=PIK3C2A PE=1 SV=2"	"0"	"1"	"1"	"1"	"1686"	"190.6"	"8.02"	"251.86"	""	"1"	""	"cell organization and biogenesis;other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00168, Pf00454, Pf00613, Pf00787, Pf00792, Pf00794"	"5286"	"ENSG00000011405"	"PIK3C2A"	"B0LPH2; B4E2G4; hsa:5286; O00443; Q14CQ9"	"Glioblastoma signaling pathways; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Microglia pathogen phagocytosis pathway; Osteoblast differentiation and related diseases; Insulin signaling; Regulation of actin cytoskeleton; DNA damage response (only ATM dependent)"	"Golgi Associated Vesicle Biogenesis; Clathrin-mediated endocytosis; Synthesis of PIPs at the plasma membrane; Synthesis of PIPs at the Golgi membrane; Synthesis of PIPs at the early endosome membrane; Synthesis of PIPs at the late endosome membrane"	"14"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96C19"	"EF-hand domain-containing protein D2 OS=Homo sapiens OX=9606 GN=EFHD2 PE=1 SV=1"	"3"	"1"	"1"	"1"	"240"	"26.7"	"5.20"	"251.76"	""	"1"	""	""	"other membranes"	"other molecular function"	"Pf13499"	"79180"	"ENSG00000142634"	"EFHD2"	"hsa:79180; Q5JYW9; Q96C19"	""	"RHOD GTPase cycle"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96RS6"	"NudC domain-containing protein 1 OS=Homo sapiens OX=9606 GN=NUDCD1 PE=1 SV=2"	"1"	"1"	"1"	"1"	"583"	"66.7"	"5.11"	"251.70"	""	"1"	""	"other biological processes"	"cytosol;nucleus"	""	"Pf04969"	"84955"	"ENSG00000120526"	"NUDCD1"	"B4DVX6; hsa:84955; Q4G130; Q8NDQ5; Q8NG18; Q96RS6; Q96SI4; Q9BVR5"	""	""	"0"	"0"	"23.7"	"115.6"	"97.1"	"13.3"	"83.9"	"24.8"	"42.9"	"32.8"	"58.2"	"68.7"	"123.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q7L1Q6"	"Basic leucine zipper and W2 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=BZW1 PE=1 SV=1"	"1"	"1"	"1"	"1"	"419"	"48.0"	"5.92"	"251.31"	""	"1"	""	"other biological processes"	"other cell component"	""	"Pf02020"	"9689"	"ENSG00000082153"	"BZW1"	"B4DLZ8; B4DWF7; hsa:9689; Q14281; Q15394; Q7L1Q6; Q9BUY0"	""	""	"0"	"0"	"21.4"	"206.6"	"143.2"	"10.7"	"87.9"	"31.6"	"43.1"	"27.9"	"35.7"	"50.1"	"84.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q3B7T1"	"Erythroid differentiation-related factor 1 OS=Homo sapiens OX=9606 GN=EDRF1 PE=1 SV=1"	"0"	"1"	"1"	"1"	"1238"	"138.4"	"6.33"	"251.30"	""	"1"	""	"other biological processes"	"nucleus"	""	""	"26098"	"ENSG00000107938"	"EDRF1"	"B2RC65; hsa:26098; Q3B7T1; Q3KR40; Q4G190; Q5VZQ4; Q8IZ74; Q9Y3W4"	""	""	"0"	"0"	"17.3"	"50.0"	"34.7"	"14.0"	"31.0"	"20.1"	"34.7"	"36.1"	"48.5"	"52.1"	"74.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P27708"	"CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3"	"0"	"1"	"1"	"1"	"2225"	"242.8"	"6.46"	"250.62"	""	"1"	""	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00117, Pf00185, Pf00988, Pf01979, Pf02142, Pf02729, Pf02786, Pf02787"	"790"	"ENSG00000084774"	"CAD"	"D6W552; hsa:790; P27708; Q6P0Q0; Q96CK3"	"Endothelin pathways; Amino acid metabolism; Pyrimidine metabolism"	"Pyrimidine biosynthesis"	"4"	"0"	"7.3"	"21.3"	"21.2"	"4.9"	"22.7"	"9.0"	"11.8"	"8.2"	"12.8"	"16.5"	"22.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9BZH6"	"WD repeat-containing protein 11 OS=Homo sapiens OX=9606 GN=WDR11 PE=1 SV=1"	"1"	"1"	"1"	"1"	"1224"	"136.6"	"6.92"	"250.41"	""	"1"	""	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	""	""	"55717"	"ENSG00000120008"	"WDR11"	"hsa:55717; Q5VWA1; Q9BZH6; Q9P2J6"	""	"RHOH GTPase cycle"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96IY1"	"Kinetochore-associated protein NSL1 homolog OS=Homo sapiens OX=9606 GN=NSL1 PE=1 SV=3"	"4"	"1"	"2"	"1"	"281"	"32.1"	"6.79"	"249.55"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf08641"	"25936"	"ENSG00000117697"	"NSL1"	"E7ETD5; hsa:25936; Q5SY75; Q96IY1; Q9H2M5; Q9NRN8; Q9Y415"	""	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"6"	"0"	"31.8"	"85.6"	"130.6"	"14.2"	"75.2"	"34.5"	"132.7"	"98.6"	"208.1"	"345.3"	"1398.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UBC2"	"Epidermal growth factor receptor substrate 15-like 1 OS=Homo sapiens OX=9606 GN=EPS15L1 PE=1 SV=1"	"1"	"1"	"1"	"1"	"864"	"94.2"	"5.11"	"248.84"	""	"1"	""	"transport"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf12763"	"58513"	"ENSG00000127527"	"EPS15L1"	"A2RRF3; A5PL29; B4DKA3; hsa:58513; Q9UBC2"	"EGF/EGFR signaling pathway"	"Cargo recognition for clathrin-mediated endocytosis; EGFR downregulation"	"4"	"0"	"25.9"	"13.6"	"16.1"	"26.5"	"24.9"	"37.5"	"23.9"	"16.7"	"26.3"	"9.2"	"2.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O15084"	"Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A OS=Homo sapiens OX=9606 GN=ANKRD28 PE=1 SV=5"	"1"	"1"	"1"	"1"	"1053"	"112.9"	"6.25"	"248.76"	""	"1"	""	""	"cytosol;nucleus"	""	"Pf00023, Pf13637"	"23243"	"ENSG00000206560"	"ANKRD28"	"B4DES5; hsa:23243; O15084; Q1WWL4; Q29RW6; Q3B857; Q6ULS0; Q6ZT57"	""	"Telomere Extension By Telomerase; COPII-mediated vesicle transport"	"2"	"0"	"10.5"	"15.0"	"18.8"	"6.9"	"13.7"	"8.8"	"13.0"	"3.8"	"8.4"	"9.8"	"11.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P36871"	"Phosphoglucomutase-1 OS=Homo sapiens OX=9606 GN=PGM1 PE=1 SV=3"	"1"	"1"	"1"	"1"	"562"	"61.4"	"6.76"	"247.93"	""	"1"	""	"other metabolic processes"	"non-structural extracellular;cytosol;other cell component"	"other molecular function"	"Pf02878, Pf02879, Pf02880"	"5236"	"ENSG00000079739"	"PGM1"	"B2R5N9; B4DPV0; hsa:5236; P36871; Q16105; Q16106; Q5BKZ9; Q6NW22; Q86U74; Q96J40; Q9NTY4"	"Ectoderm differentiation; Clear cell renal cell carcinoma pathways; Glycogen synthesis and degradation; Opioid receptor pathways; Disorders of galactose metabolism ; Disorders of fructose metabolism; UDP-derived sugars synthesis in fibroblasts; Glucuronidation"	"Neutrophil degranulation; Glycogen synthesis; Glycogen breakdown (glycogenolysis); Galactose catabolism; Defective PGM1 causes PGM1-CDG"	"13"	"0"	"70.7"	"385.9"	"292.3"	"32.9"	"245.0"	"73.3"	"127.0"	"89.5"	"140.5"	"150.5"	"306.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TAX7"	"Mucin-7 OS=Homo sapiens OX=9606 GN=MUC7 PE=1 SV=2"	"2"	"1"	"1"	"1"	"377"	"39.1"	"8.78"	"247.75"	""	"1"	""	"stress response;other biological processes"	"plasma membrane;other membranes;ER/Golgi"	""	""	"4589"	"ENSG00000171195"	"MUC7"	"hsa:4589; Q8TAX7; Q9UCD7; Q9UCD8"	""	"Dectin-2 family; Termination of O-glycan biosynthesis; Defective GALNT3 causes HFTC; Defective C1GALT1C1 causes TNPS; Defective GALNT12 causes CRCS1"	"6"	"0"	"10.2"	"45.9"	"57.0"	"6.1"	"40.1"	"19.6"	"22.4"	"18.2"	"787.9"	"50.1"	"45.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P51649"	"Succinate-semialdehyde dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH5A1 PE=1 SV=2"	"2"	"1"	"1"	"1"	"535"	"57.2"	"8.28"	"246.75"	""	"1"	""	"other metabolic processes;developmental processes"	"mitochondrion"	"other molecular function"	"Pf00171"	"7915"	"ENSG00000112294"	"ALDH5A1"	"B2RD26; G5E949; hsa:7915; P51649; Q546H9; Q8N3W6"	"Fragile X syndrome"	"Degradation of GABA"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96SU4"	"Oxysterol-binding protein-related protein 9 OS=Homo sapiens OX=9606 GN=OSBPL9 PE=1 SV=2"	"1"	"1"	"1"	"1"	"736"	"83.1"	"6.18"	"246.41"	""	"1"	""	"other metabolic processes;transport"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf00169, Pf01237"	"114883"	"ENSG00000117859"	"OSBPL9"	"B1AKJ8; B3KPQ4; D3DQ31; hsa:114883; Q5TFC0; Q6IA67; Q86YQ3; Q8NB17; Q8TAS8; Q96SK4; Q96SU4; Q9H9X2"	""	"Synthesis of bile acids and bile salts"	"1"	"0"	"13.4"	"40.9"	"35.7"	"9.3"	"23.4"	"10.3"	"19.5"	"14.9"	"18.5"	"26.0"	"48.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96C24"	"Synaptotagmin-like protein 4 OS=Homo sapiens OX=9606 GN=SYTL4 PE=1 SV=2"	"2"	"1"	"2"	"1"	"671"	"76.0"	"8.98"	"246.28"	""	"1"	""	"cell-cell signaling;cell organization and biogenesis;stress response;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle"	"signal transduction activity or receptor binding;other molecular function"	"Pf00168, Pf02318"	"94121"	"ENSG00000102362"	"SYTL4"	"hsa:94121; Q5H9J3; Q5JPG8; Q8N9P4; Q96C24; Q9H4R0; Q9H4R1"	"Deregulation of Rab and Rab effector genes in bladder cancer"	"Platelet degranulation"	"2"	"0"	"50.9"	"43.7"	"54.3"	"40.8"	"43.5"	"56.4"	"160.3"	"84.7"	"110.2"	"126.4"	"142.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9UL03"	"Integrator complex subunit 6 OS=Homo sapiens OX=9606 GN=INTS6 PE=1 SV=1"	"1"	"1"	"1"	"1"	"887"	"100.3"	"8.62"	"246.21"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus"	"other molecular function"	"Pf13519, Pf15300"	"26512"	"ENSG00000102786"	"INTS6"	"hsa:26512; Q0P664; Q6PJP4; Q9UFK0; Q9UL03; Q9Y5M9"	""	"RNA polymerase II transcribes snRNA genes"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q6KC79"	"Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2"	"1"	"1"	"1"	"1"	"2804"	"315.9"	"7.91"	"243.48"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf12765, Pf12830"	"25836"	"ENSG00000164190"	"NIPBL"	"hsa:25836; Q6KC79; Q6KCD6; Q6N080; Q6ZT92; Q7Z2E6; Q8N4M5; Q9Y6Y3; Q9Y6Y4"	"Cohesin complex - Cornelia de Lange syndrome; NIPBL role in DNA damage - Cornelia de Lange syndrome"	"Cohesin Loading onto Chromatin"	"3"	"0"	"62.9"	"51.5"	"69.9"	"41.8"	"63.5"	"59.2"	"89.8"	"55.0"	"71.2"	"79.0"	"116.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q96JB2"	"Conserved oligomeric Golgi complex subunit 3 OS=Homo sapiens OX=9606 GN=COG3 PE=1 SV=3"	"1"	"1"	"1"	"1"	"828"	"94.0"	"5.57"	"242.82"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi"	""	"Pf04136"	"83548"	"ENSG00000136152"	"COG3"	"B2RAW5; hsa:83548; Q5VT70; Q8IXX4; Q96JB2; Q9BZ92"	""	"COPI-mediated anterograde transport; Intra-Golgi traffic; Retrograde transport at the Trans-Golgi-Network"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"A6NCE7"	"Microtubule-associated proteins 1A/1B light chain 3 beta 2 OS=Homo sapiens OX=9606 GN=MAP1LC3B2 PE=2 SV=1"	"6"	"1"	"1"	"1"	"125"	"14.6"	"8.68"	"242.65"	""	"1"	""	"cell organization and biogenesis;other metabolic processes;stress response"	"other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02991"	"643246"	"ENSG00000258102"	"MAP1LC3B2"	"A6NCE7; hsa:643246"	""	""	"0"	"0"	"76.6"	"109.6"	"112.9"	"74.4"	"135.6"	"79.5"	"134.4"	"122.9"	"141.0"	"185.4"	"311.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O94826"	"Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1"	"1"	"1"	"1"	"1"	"608"	"67.4"	"7.12"	"242.58"	""	"1"	""	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00515, Pf13181"	"9868"	"ENSG00000154174"	"TOMM70"	"D3DN48; hsa:9868; O94826"	"Mitochondrial immune response to SARS-CoV-2; SARS-CoV-2 B.1.1.7 variant antagonises innate immune activation; SARS-CoV-2 mitochondrial chronic oxidative stress and endothelial dysfunction"	"Ub-specific processing proteases; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Mitochondrial protein import; DDX58/IFIH1-mediated induction of interferon-alpha/beta; SARS-CoV-1 activates/modulates innate immune responses; PINK1-PRKN Mediated Mitophagy"	"9"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P21579"	"Synaptotagmin-1 OS=Homo sapiens OX=9606 GN=SYT1 PE=1 SV=1"	"2"	"1"	"1"	"1"	"422"	"47.5"	"8.12"	"242.38"	""	"1"	""	"cell-cell signaling;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00168"	"6857"	"ENSG00000067715"	"SYT1"	"hsa:6857; P21579; Q6AI31"	"Synaptic vesicle pathway"	"Glutamate Neurotransmitter Release Cycle; Neurexins and neuroligins; Cargo recognition for clathrin-mediated endocytosis; Serotonin Neurotransmitter Release Cycle; Norepinephrine Neurotransmitter Release Cycle; Dopamine Neurotransmitter Release Cycle; Acetylcholine Neurotransmitter Release Cycle; GABA synthesis, release, reuptake and degradation; Toxicity of botulinum toxin type B (botB); Toxicity of botulinum toxin type G (botG)"	"12"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86YB8"	"ERO1-like protein beta OS=Homo sapiens OX=9606 GN=ERO1B PE=1 SV=2"	"2"	"1"	"1"	"1"	"467"	"53.5"	"7.99"	"242.34"	""	"1"	""	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf04137"	"56605"	"ENSG00000086619"	"ERO1B"	"B4DF57; hsa:56605; Q5T1H4; Q86YB8; Q8IZ11; Q9NR62"	""	"Insulin processing"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86YR7"	"Probable guanine nucleotide exchange factor MCF2L2 OS=Homo sapiens OX=9606 GN=MCF2L2 PE=2 SV=3"	"1"	"1"	"1"	"1"	"1114"	"126.9"	"6.42"	"241.68"	""	"1"	""	"other biological processes"	"other cell component"	"enzyme regulator activity"	"Pf00621, Pf13716"	"23101"	"ENSG00000053524"	"MCF2L2"	"hsa:23101; O94942; Q6P2B8; Q6ZVJ5; Q86YR7; Q8N318"	""	""	"0"	"0"	"8.0"	"16.0"	"11.6"	"7.0"	"10.9"	"2.9"	"37.9"	"108.0"	"100.1"	"61.1"	"65.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43920"	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 OS=Homo sapiens OX=9606 GN=NDUFS5 PE=1 SV=3"	"7"	"1"	"1"	"1"	"106"	"12.5"	"9.14"	"241.07"	""	"1"	""	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf10200"	"4725"	"ENSG00000168653"	"NDUFS5"	"hsa:4725; O43920"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"28.5"	"88.6"	"85.4"	"22.4"	"72.2"	"34.1"	"125.9"	"110.1"	"156.1"	"275.3"	"386.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q5VIR6"	"Vacuolar protein sorting-associated protein 53 homolog OS=Homo sapiens OX=9606 GN=VPS53 PE=1 SV=1"	"1"	"1"	"1"	"1"	"699"	"79.6"	"6.02"	"240.14"	""	"1"	""	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"11.2"	"45.7"	"34.6"	"14.8"	"34.1"	"21.0"	"24.1"	"19.7"	"27.4"	"39.2"	"57.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HAU5"	"Regulator of nonsense transcripts 2 OS=Homo sapiens OX=9606 GN=UPF2 PE=1 SV=1"	"1"	"1"	"1"	"1"	"1272"	"147.7"	"5.69"	"238.79"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02854, Pf04050"	"26019"	"ENSG00000151461"	"UPF2"	"A6NLJ5; D3DRS0; hsa:26019; Q14BM1; Q5W0J4; Q8N8U1; Q9H1J2; Q9HAU5; Q9NWL1; Q9P2D9; Q9Y4M9"	""	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	"2"	"0"	"4.6"	"20.4"	"17.6"	"5.5"	"11.5"	"7.1"	"15.3"	"12.7"	"20.9"	"22.0"	"37.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"P55081"	"Microfibrillar-associated protein 1 OS=Homo sapiens OX=9606 GN=MFAP1 PE=1 SV=2"	"4"	"1"	"1"	"1"	"439"	"51.9"	"4.98"	"237.95"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"extracellular matrix;cytoskeleton;nucleus"	""	"Pf06991"	"4236"	"ENSG00000140259"	"MFAP1"	"hsa:4236; P55081; Q86TG6"	"Canonical and non-canonical Notch signaling; Ciliary landscape"	"mRNA Splicing - Major Pathway"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8TAV0"	"Protein FAM76A OS=Homo sapiens OX=9606 GN=FAM76A PE=2 SV=1"	"2"	"1"	"1"	"1"	"307"	"35.0"	"9.19"	"237.88"	""	"1"	""	""	"nucleus"	""	"Pf16046"	"199870"	"ENSG00000009780"	"FAM76A"	"B4DWT3; hsa:199870; O95565; O95566; Q8N7J5; Q8TAV0"	""	""	"0"	"0"	"66.2"	"216.8"	"209.8"	"56.1"	"186.9"	"83.2"	"167.2"	"104.2"	"153.2"	"204.9"	"366.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9HAS0"	"Protein Njmu-R1 OS=Homo sapiens OX=9606 GN=C17orf75 PE=1 SV=2"	"4"	"1"	"1"	"1"	"396"	"44.6"	"5.03"	"237.37"	""	"1"	""	"cell organization and biogenesis;transport"	"ER/Golgi;other cell component"	""	"Pf15053"	"64149"	"ENSG00000108666"	"C17orf75"	"hsa:64149; Q7Z2H4; Q9HAS0"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q4U2R6"	"39S ribosomal protein L51, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL51 PE=1 SV=1"	"9"	"1"	"1"	"1"	"128"	"15.1"	"11.27"	"237.21"	""	"1"	""	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf10244"	"51258"	"ENSG00000111639"	"MRPL51"	"hsa:51258; Q4U2R6; Q96Q57; Q9BQ36; Q9P0N7"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"4.4"	"18.6"	"20.0"	"8.6"	"14.6"	"8.5"	"6.1"	"5.8"	"2.4"	"9.5"	"16.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43909"	"Exostosin-like 3 OS=Homo sapiens OX=9606 GN=EXTL3 PE=1 SV=1"	"1"	"1"	"1"	"1"	"919"	"104.7"	"6.51"	"237.19"	""	"1"	""	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus"	"other molecular function"	"Pf03016, Pf09258"	"2137"	"ENSG00000012232"	"EXTL3"	"D3DST8; hsa:2137; O00225; O43909; Q53XT3"	"Proteoglycan biosynthesis"	"XBP1(S) activates chaperone genes"	"2"	"0"	"6.4"	"18.3"	"19.8"	"4.4"	"13.7"	"5.5"	"12.5"	"13.1"	"30.6"	"34.9"	"62.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9NRW3"	"DNA dC->dU-editing enzyme APOBEC-3C OS=Homo sapiens OX=9606 GN=APOBEC3C PE=1 SV=2"	"3"	"1"	"1"	"1"	"190"	"22.8"	"7.59"	"237.11"	""	"1"	""	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf18782"	"27350"	"ENSG00000244509"	"APOBEC3C"	"B2R884; hsa:27350; Q5JZ92; Q7Z2N7; Q96F12; Q9NRW3"	""	"Formation of the Editosome"	"2"	"0"	"29.4"	"42.6"	"42.9"	"17.4"	"44.2"	"24.8"	"60.4"	"37.6"	"49.8"	"59.3"	"95.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q13217"	"DnaJ homolog subfamily C member 3 OS=Homo sapiens OX=9606 GN=DNAJC3 PE=1 SV=1"	"1"	"1"	"1"	"1"	"504"	"57.5"	"6.15"	"236.85"	""	"1"	""	"protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00226, Pf00515, Pf13181, Pf13432"	"5611"	"ENSG00000102580"	"DNAJC3"	"hsa:5611; Q13217; Q86WT9; Q8N4N2"	"Photodynamic therapy-induced unfolded protein response"	"Neutrophil degranulation; Viral mRNA Translation; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; XBP1(S) activates chaperone genes"	"6"	"0"	"27.6"	"52.2"	"51.1"	"14.8"	"37.4"	"24.9"	"90.7"	"84.4"	"127.8"	"210.9"	"429.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q99747"	"Gamma-soluble NSF attachment protein OS=Homo sapiens OX=9606 GN=NAPG PE=1 SV=1"	"2"	"1"	"1"	"1"	"312"	"34.7"	"5.41"	"236.78"	""	"1"	""	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion;ER/Golgi"	"other molecular function"	"Pf14938"	"8774"	"ENSG00000134265"	"NAPG"	"B4DFC9; hsa:8774; Q99747; Q9BUV1"	""	"COPI-mediated anterograde transport; Retrograde transport at the Trans-Golgi-Network; COPI-dependent Golgi-to-ER retrograde traffic; Intra-Golgi traffic; COPII-mediated vesicle transport"	"5"	"0"	"15.4"	"54.8"	"49.7"	"20.9"	"42.1"	"26.6"	"37.3"	"34.3"	"47.6"	"56.1"	"94.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q86Y56"	"Dynein assembly factor 5, axonemal OS=Homo sapiens OX=9606 GN=DNAAF5 PE=1 SV=4"	"1"	"1"	"1"	"1"	"855"	"93.5"	"6.42"	"236.07"	""	"1"	""	"cell organization and biogenesis;other biological processes"	"other cell component"	"other molecular function"	""	"54919"	"ENSG00000164818"	"DNAAF5"	"hsa:54919; Q69YL1; Q86Y56; Q96FI9; Q9NX75"	"Ciliopathies"	""	"1"	"0"	"30.3"	"128.6"	"102.1"	"21.1"	"86.5"	"29.5"	"44.9"	"41.2"	"52.5"	"72.5"	"120.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"O43633"	"Charged multivesicular body protein 2a OS=Homo sapiens OX=9606 GN=CHMP2A PE=1 SV=1"	"4"	"1"	"2"	"1"	"222"	"25.1"	"5.97"	"236.05"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf03357"	"27243"	"ENSG00000130724"	"CHMP2A"	"B2R4W6; hsa:27243; O43633; Q3ZTT0"	""	"Budding and maturation of HIV virion; Endosomal Sorting Complex Required For Transport (ESCRT); HCMV Late Events; Late endosomal microautophagy; Sealing of the nuclear envelope (NE) by ESCRT-III; Lysosome Vesicle Biogenesis; Macroautophagy; Pyroptosis; Translation of Replicase and Assembly of the Replication Transcription Complex; Translation of Replicase and Assembly of the Replication Transcription Complex"	"10"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q8N1G2"	"Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 OS=Homo sapiens OX=9606 GN=CMTR1 PE=1 SV=1"	"2"	"1"	"1"	"1"	"835"	"95.3"	"7.05"	"235.55"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01585, Pf01728"	"23070"	"ENSG00000137200"	"CMTR1"	"A8K949; hsa:23070; Q14670; Q8N1G2; Q96FJ9"	""	""	"0"	"0"	"3.0"	"13.1"	"13.7"	"1.4"	"9.7"	"8.9"	"11.3"	"9.1"	"16.3"	"17.4"	"33.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q9H6Y2"	"WD repeat-containing protein 55 OS=Homo sapiens OX=9606 GN=WDR55 PE=1 SV=2"	"2"	"1"	"1"	"1"	"383"	"42.0"	"4.92"	"235.51"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf00400, Pf12894"	"54853"	"ENSG00000120314"	"WDR55"	"hsa:54853; Q9H6Y2; Q9NXK4"	""	""	"0"	"0"	"17.4"	"55.3"	"47.5"	"13.7"	"40.8"	"24.9"	"55.1"	"58.7"	"55.8"	"70.7"	"107.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"IsMasterProtein"	"Q15695"	"Putative U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1 OS=Homo sapiens OX=9606 GN=ZRSR2P1 PE=5 SV=2"	"1"	"1"	"1"	"1"	"479"	"57.6"	"9.36"	"235.24"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00642"	""	""	"ZRSR2P1"	"B2R901; Q13570; Q15695; Q2M3R8"	""	""	"0"	"0"	"86.9"	"96.9"	"109.9"	"80.1"	"88.8"	"77.5"	"83.2"	"57.3"	"73.6"	"75.5"	"105.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""